Podcasts about hba1c

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Welcome back to our weekend Cabral HouseCall shows!   This is where we answer our community's wellness, weight loss, and anti-aging questions to help people get back on track!   Check out today's questions:    Kay: Hi Dr. Cabral, Thanks for your very informative and interesting podcasts. How would you advise a post-menopausal 60 y.o family member if they tested low in ferritin (39.4 ng/mL)? I've read that this biomarker shows how much energy your body's cells have and low levels would result in symptoms like fatigue, low energy/easily tired and excessive hair shedding. This family member suffers from these symptoms. Other biomarkers revealed low AM cortisol and low LDL-C/ApoB ratio (1.1) and low basal metabolic rate of 1143 kcals/day. Although her TSH tested normal (1.3 uIU/mL), she's been on levothyroxine 75 mcg to manage hypothyroid. Her high-sensitivity CRP was not optimal at 1.49 mg/L and she has a family history of heart disease. What would you recommend for this family member? Thanks      Earl: I am currently on 20 mg of lisinopril daily. Also, my GFR is 62. Would either of these be a concern when considering creatine?       Alesi: Dr.Cabral, can you please explain Alpha-gal syndrom? Why does it happen, how to confirm it by testing and how would you approach it? Is it treatable? Thank you      Peter: Hello, Dr.Cabral. I am an integrative health practitioner and would like to thank you for helping me understand the underlying causes of human imbalances. There is one thing that makes no sense to me though…regarding IgG testing, why would you recommend to test every year? Why doesn't suffice to test once and simply stay away from intolerant food items? Why would these intolerances change? Also, in my country there are IgG4 vs IgG1-3 testing options, what are the differences? Thank you very much for your time and knowledge you share with us.       Dipali: Hi I want to start 7 days detox plan, I already did your minerals and heavy metal test, I got my results back. My question is I am taking berberine, oregano oil and magnesium citrate,( I am prediabetic my Hba1c is 6.2)do I need to stop before starting detox method. Thanks       Thank you for tuning into today's Cabral HouseCall and be sure to check back tomorrow where we answer more of our community's questions!      - - - Show Notes and Resources: StephenCabral.com/3774 - - - Get a FREE Copy of Dr. Cabral's Book: The Rain Barrel Effect - - - Join the Community & Get Your Questions Answered: CabralSupportGroup.com - - - Dr. Cabral's Most Popular At-Home Lab Tests: > Complete Minerals & Metals Test (Test for mineral imbalances & heavy metal toxicity) - - - > Complete Candida, Metabolic & Vitamins Test (Test for 75 biomarkers including yeast & bacterial gut overgrowth, as well as vitamin levels) - - - > Complete Stress, Mood & Metabolism Test (Discover your complete thyroid, adrenal, hormone, vitamin D & insulin levels) - - - > Complete Food Sensitivity Test (Find out your hidden food sensitivities) - - - > Complete Omega-3 & Inflammation Test (Discover your levels of inflammation related to your omega-6 to omega-3 levels) - - - Get Your Question Answered On An Upcoming HouseCall: StephenCabral.com/askcabral - - - Would You Take 30 Seconds To Rate & Review The Cabral Concept? The best way to help me spread our mission of true natural health is to pass on the good word, and I read and appreciate every review!  

Doctor Mau Informa ®️ #drmauinforma Cuando discutimos la diabetes tipo 2 y la prediabetes, nuestro enfoque se centra casi exclusivamente en restringir los carbohidratos y perder peso. Sin embargo, los datos de los ensayos clínicos más recientes revelan un punto ciego enorme en nuestros paradigmas de atención: el músculo esquelético es nuestro órgano de eliminación de glucosa más grande, e ignorarlo acelera el envejecimiento metabólico. En este episodio, desglosamos las pautas clínicas y los datos de ensayos más recientes que demuestran por qué el entrenamiento de hipertrofia mecánica funciona como una poderosa intervención no farmacológica para el control del azúcar en sangre, incluso para personas con un peso normal. En este episodio aprenderás: → Por qué la diabetes tipo 2 actúa como un factor de riesgo independiente para la sarcopenia acelerada y el declive de la función muscular. → Los datos moleculares que demuestran que el entrenamiento de resistencia mejora la HbA1c en aproximadamente un 0.57% y la glucosa en ayunas en ~7 mg/dL. → Por qué el entrenamiento de hipertrofia es significativamente superior al entrenamiento de resistencia a la fatiga para la inflamación sistémica y la retención de masa magra. → Los sorprendentes resultados del ensayo Kobayashi: por qué el entrenamiento de fuerza venció al cardio en la diabetes tipo 2 de peso normal. → Los parámetros de programación exactos de la Asociación Americana de Diabetes y el ACSM necesarios para optimizar la eliminación metabólica en la práctica.

In case you missed it, this is a replayed moment from last year and one of the most viewed podcast episodes I've ever shared specifically for hygienists. And honestly, this topic is more important than ever because efficient perio charting in Dentrix directly impacts diagnosis, patient care, insurance documentation, and clinical consistency.

In this conversation, Dr. Reza Ardalan sits down with Dr. Hugh Coyne, a London-based family medicine practitioner and the son of a pediatric dentist, who built Coyne Medical with his wife and clinical partner Dr. Lucy Coyne specifically to practice the kind of preventive medicine the NHS 10-minute appointment window does not allow. His training at Imperial College London and postgraduate work in obstetrics and gynecology, pediatric health, and sports medicine give him a panoramic view of the screening opportunities most dentists are sitting on without realizing it. Dr. Coyne walks through the short blood panel he would build into every dental practice: HbA1c for diabetes risk that directly changes wound healing and periodontal outcomes, highly sensitive CRP for the kind of cardiovascular inflammation a UK Biobank study of over 400,000 people linked to a 61% higher risk of cardiovascular death, vitamin D with the K2 pairing that keeps calcium out of arterial walls, renal function, and a full blood count. From there, Dr. Coyne and Dr. Ardalan move into the oral microbiome shift from pathogen elimination to ecosystem restoration, the role of P. gingivalis in rheumatoid arthritis through citrullinated protein antibodies, and the cardiometabolic markers most patients never get tested for, including apolipoprotein B and lipoprotein(a). The third act covers GLP-1 medications, the Gila monster origin story, the medieval cautionary tale of Sancho the Fat, and the dental-chair implications most patients will never volunteer on a health history form. In this Episode:  The short blood panel any dental practice can start with: HbA1c, highly sensitive CRP, vitamin D, renal function, and a full blood count Why vitamin D supplementation without vitamin K2 may direct calcium into the wrong tissues, including arterial walls How a UK Biobank study of more than 400,000 people linked elevated hs-CRP to a 61% higher risk of cardiovascular death in patients otherwise considered well What the 87% of patients open to in-chair screening tells you about how to introduce blood testing in your practice without losing trust The rule of halves for blood pressure, and why a 158 reading caught on a second visit can be profoundly consequential for a patient's long-term survival How the oral microbiome model has shifted from pathogen elimination to ecosystem restoration, and what that changes about prevention Why P. gingivalis turns up in rheumatoid arthritis tissue, and how oral pathogens correlate with colorectal, pancreatic, and esophageal cancers The bachelor-party analogy for apolipoprotein B and lipoprotein(a), and why every dentist should know their own Lp(a) number What every dental practice needs to know before sedating a patient on a GLP-1 medication   Dr. Hugh Coyne is a London-based GP and the co-founder, with his wife Dr. Lucy Coyne, of Coyne Medical, a family medicine practice focused on preventive care and the early detection of disease. Dr. Hugh Coyne trained at Imperial College London with postgraduate degrees in obstetrics and gynecology, pediatric health, and sports medicine, and is a featured speaker at the Wellness Dental Forum 2026. Find him on Instagram and TikTok at @drhughcoyne and the clinic at @coyne_medical. Want to go deeper on the oral–systemic connection? Dentistry & Whole-Body Health is a 3-part live CE series on reading the medical signals hiding in your patients' bloodwork — and knowing what to do with them. Session 1:  Hidden Signals · Saturday, November 7, 2026 The bloodwork your patients already have, read through a dentist's lens. HbA1c, hs-CRP, vitamin D, CBC — and when to monitor, pause, or refer. Session 2: Cardiovascular Clues · Saturday, November 21, 2026 The lipid markers most panels skip (ApoB, Lp(a)) and the oral–heart connection behind them. Yes — this is the bachelor-party one. Session 3: The New Weight Loss Era · Saturday, December 5, 2026 What GLP-1s are quietly doing to how your patients eat, metabolize, and heal — and the chairside adjustments that come with it. All 3-hour sessions run 8 AM PT / 11 AM ET / 4 PM UK, with 30-day recording access if you can't make it live. 9 AGD-PACE-approved CE credits across the series. Nothing here asks you to become a doctor — it gives you the medical layer that's already shaping your outcomes. Enrollment opens soon: $1,497 → Or try a single session — $625 More details coming soon!

Witam Państwa, nazywam się Jarosław Drożdż, pracuję w Centralnym Szpitalu Klinicznym Uniwersytetu Medycznego w Łodzi, skąd nagrywam podcast Kardio Know-How. W tym odcinku omawiam kolejną część badań opublikowanych podczas kongresu ACC 2026. Już za tydzień w Gdańsku odbędzie się największy doroczny kongres Europejskiego Towarzystwa Nadciśnienia Tętniczego ESH, co jest ogromnym sukcesem prof. Krzysztofa Narkiewicza i całego środowiska polskich hipertensjologów, a jednym z głównych tematów pozostaje nadal niedostatecznie skuteczne leczenie nadciśnienia tętniczego mimo dostępności nowoczesnych terapii SPC i jasno określonych celów terapeutycznych. Analizując tegoroczny kongres ACC pod kątem nadciśnienia tętniczego, szczególną uwagę zwróciłem na badanie MOMENTUM prowadzone przez Deepaka Bhata, dotyczące hiperkortyzolemii jako potencjalnie bardzo częstej przyczyny wtórnego nadciśnienia tętniczego. Kortyzol, będący hormonem stresu produkowanym przez korę nadnerczy, poprzez aktywację układu RAA, retencję sodu, wzrost aktywności układu współczulnego i zaburzenia funkcji śródbłonka może prowadzić do nadciśnienia, niewydolności serca, udarów i zawałów serca. W badaniu wykazano, że ponad 27% pacjentów leczonych trzema lub czterema lekami hipotensyjnymi spełnia kryteria hiperkortyzolemii, a część z nich ma dodatkowo guzy nadnerczy, co sugeruje, że problem ten może być znacznie częstszy niż dotąd sądziliśmy. Co ważne, pacjentów tych praktycznie nie da się odróżnić klinicznie od pozostałych chorych z nadciśnieniem, choć częściej mają gorszą funkcję nerek, wyższy poziom glikemii oraz większe ryzyko migotania przedsionków, choroby wieńcowej i niewydolności serca. Wyniki badania opublikowano w JACC: https://www.jacc.org/doi/10.1016/j.jacadv.2026.102596 i mogą one stać się początkiem rozwoju nowych terapii ukierunkowanych na zaburzenia osi kortyzolowej. Drugim ciekawym doniesieniem było badanie KARDINAL dotyczące leku Tonlamarsen — oligonukleotydu antysensowego podawanego podskórnie raz w miesiącu, który hamuje produkcję angiotensynogenu wątrobowego i pozwala obniżyć ciśnienie tętnicze średnio o około 10 mmHg. Wyniki te opublikowano w JACC: https://www.jacc.org/doi/10.1016/j.jacc.2026.03.034 i pokazują, że przyszłość leczenia nadciśnienia może należeć do terapii iniekcyjnych działających miesiącami zamiast codziennego przyjmowania tabletek. Trzecim niezwykle ważnym wątkiem była koncepcja GoFreshRx, przypominająca, że skuteczna walka z nadciśnieniem nie polega wyłącznie na farmakoterapii, ale również na zmianie środowiska żywieniowego i ograniczaniu dostępności produktów prowadzących do otyłości oraz chorób sercowo-naczyniowych. W prezentacjach przypomniano dwa ważne artykuły z NEJM pokazujące, że poprawa jakości dostępnej żywności może obniżać ciśnienie tętnicze, BMI, cholesterol LDL oraz HbA1c w całych populacjach: https://www.nejm.org/doi/full/10.1056/NEJMoa2105675 oraz https://www.nejm.org/doi/full/10.1056/NEJMoa1800389. Nadal jednak uważam, że podstawą skutecznego leczenia nadciśnienia pozostają szybkie decyzje terapeutyczne podejmowane już przez pierwszego lekarza, stosowanie leków złożonych SPC, utrzymywanie prawidłowej masy ciała przez całe dorosłe życie oraz regularna aktywność fizyczna, bo bez tego nawet najbardziej nowoczesne terapie nie odwrócą skutków współczesnego stylu życia. Szczegółowy TRANSKRYPT do odcinka.Podcast jest przeznaczony wyłącznie dla osób z profesjonalnym wykształceniem medycznym.

Fast jeder zweite Erwachsene in westlichen Industrienationen ist bereits insulinresistent – oft ohne es zu wissen. In dieser Folge sprechen wir darüber, warum HbA1c und Nüchternglukose häufig erst spät auffällig werden und warum Nüchterninsulin und HOMA-Index wichtige Marker für eine frühe Einschätzung des Zuckerstoffwechsels sein können.

PCOS may officially be getting a new name — PMOS (Polyendocrine Metabolic Ovarian Syndrome) — and honestly? It's about time.In this episode of The Balanced Body Podcast, Hormone Nutritionist Monika Eva breaks down what this major shift means for women struggling with stubborn weight gain, fatigue, insulin resistance, irregular cycles, fertility challenges, inflammation, cravings, burnout, and hormone imbalance.For years, women have been told PCOS was “just an ovarian issue.” Meanwhile, functional practitioners have long understood that this goes far deeper than the ovaries alone.This episode dives into:Why the PMOS name change mattersThe emotional reality of being dismissed or gaslit by “normal labs”Why weight loss resistance is often a metabolic and inflammatory issueThe connection between cortisol, insulin resistance, gut health, inflammation, detoxification, and hormone balanceWhy so many women feel exhausted, swollen, puffy, anxious, and stuck despite doing “everything right”Why symptoms matter — even if you don't officially meet PCOS criteriaThe truth about GLP-1 medications and why weight loss alone does not equal healingFunctional testing options like the DUTCH Test, GI-MAP, HTMA, fasting insulin, HbA1c, CRP, and moreIf you've ever felt frustrated by your body, dismissed by doctors, or confused about why your metabolism, hormones, energy, and weight feel so hard to manage… this episode is for you.Because this was never just about ovaries.It's about your whole body.If this episode resonated with you, send Monika a DM on Instagram with the word “PMOS” and let her know your biggest takeaway. If you're ready to investigate the root causes behind your symptoms and finally understand what your body has been trying to tell you, Monika would be honoured to support you inside The Balanced Body Method. Start with the Weight Loss & Energy Blocker Assessment here.Follow Monika on Instagram:@monikaevaLearn more about working with Monika:Monika Eva Official WebsiteThanks for listening. Please rate & review so we can reach more women with this very important information. Share with a friend whom you know would benefit from listening to The Balanced Body Podcast.Follow your host, Monika Eva, on IG here: https://www.instagram.com/monikaeevaTake my FREE Weight Loss & Energy Blocker Assessment to find out what's blocking you from releasing the weight & being energized here:https://www.monikaeva.com/whatsblockingyouLearn more about working with Monika here:https://www.monikaeva.com

Send us Fan MailIn this week's Friday Five, I'm breaking down some of the standard blood markers I commonly look at in clinic when somebody is dealing with autoimmune disease, inflammation, fatigue, or hair loss — including alopecia.One of the biggest misconceptions I see is that “normal” blood tests automatically mean everything is functioning optimally. But in reality, many people continue to struggle with symptoms despite being told their results are fine.In this episode, I explain why interpretation matters just as much as the numbers themselves, and why looking at patterns across the body can often reveal far more than one isolated marker.I discuss:• Ferritin, transferrin and the wider iron picture• Why ferritin alone may not tell the full story in inflammatory conditions• Thyroid markers beyond TSH, including Free T3, Free T4 and thyroid antibodies• The role of thyroid hormone conversion in energy, metabolism and hair health• Vitamin D and immune regulation• Zinc and its role in immune resilience, skin and hair health• White blood cells, neutrophils and lymphocyte patterns in autoimmune disease• What triglycerides can tell us about metabolism, blood sugar regulation and inflammation• Why markers like serum B12 or HbA1c may not always reflect the full picture• The importance of interpreting symptoms alongside laboratory testingThis episode is not about becoming fearful of blood tests or obsessing over numbers. It's about understanding the body more deeply and recognising that subtle shifts in markers can sometimes provide important clues long before symptoms become more significant.If you've ever been told “everything looks normal” but still feel that something is off, this episode is for you.

If you've been dealing with fatigue, weight gain, brain fog - and you're convinced that your thyroid is the problem…you might be starting in the wrong place. In this episode, I break down why the thyroid is sometimes not the first domino to fall, and why jumping straight to thyroid medication can sometimes backfire. We're talking about the real upstream drivers: high HbA1c and insulin resistance mismanaged HRT (especially in perimenopause/menopause) low iron and poor thyroid conversion Because if those are off, your thyroid is trying to function in chaos, and no amount of "perfect dosing" will fix that. If you've been chasing thyroid answers and not getting results, this episode will connect the dots and give you a smarter order of operations. Get my FREE Thyroid Video Series + Guide HERE

Stuart Tomc, a globally recognized leader in Omega 3 science, discussed his journey in the nutrition industry, emphasizing the shift from guess-based supplementation to test-based precision nutrition. He highlighted the importance of maintaining a balance between Omega 6 and Omega 3, ideally a 1:1 ratio, for optimal health. Tomc introduced Zinzino's Omega 3 blood spot test, which has tested 1.7 million people globally, revealing significant imbalances. He explained Zinzino's Balance Oil, which includes polyphenols for stability and efficacy, For the transcript and full story go to: https://www.drmanonbolliger.com/stuart-tomc  Highlights from today's episode include:  Stuart says Test, don't guess: Omega‑6:3 balance in red blood cells is the key inflammatory "vital sign" – you can take fish oil and still be completely out of the safe zone. Stuart explains fish oil ≠ fish: Most refined fish oils are "naked," stripped of protective polyphenols, so they don't behave like real food; Balance Oil restores that missing polyphenol protection. Manon states health sovereignty: People should be the CEOs of their own health—using at‑home tests to know their status and keeping (or firing) practitioners based on results. ABOUT STUART TOMC: Stuart Tomc is a globally recognized leader in omega-3 science with 30+ years in the nutrition industry and over $1 billion in supplement sales influenced worldwide. He has appeared in 6,000+ media interviews and served as Global Educator for Nordic Naturals, training teams at Whole Foods Market, Sprouts Farmers Market, The Vitamin Shoppe, and GNC, as well as independent retailers and healthcare professionals around the world. Today, Stuart is helping lead the shift from guess-based supplementation to test-based precision nutrition. Start testing. Stop guessing. We measure the AA/EPA ratio, Omega-3 Index, Gut Health Index, Vitamin D, and HbA1c — with more AI-driven tests on the way. Stuart teaches that kitchen table medicine — testing at home with high-quality products delivered to your door — is the future of the supplement industry, and he mentors partners building scalable, subscription-based businesses rooted in real data, real results, and real retention Core purpose/passion: Moving the dial on public health globally Website |     ABOUT MANON BOLLIGER, RBHT, FCAH: As a retired Naturopath 1992-2021, I saw an average of 150 patients per week and have helped people ranging from rural farmers in Nova Scotia to stressed out CEOs in Toronto to tri-athletes here in Vancouver. My resolve to educate, empower and engage people to take charge of their own health is evident in my best-selling books:  'What Patients Don't Say if Doctors Don't Ask: The Mindful Patient-Doctor Relationship' and 'A Healer in Every Household: Simple Solutions for Stress'. and What if Your Body is Smarter than You Think?  I am the Founder & CEO of The Bowen College Inc. which teaches BowenFirst™ Therapy and holds transformational workshops to achieve these goals. So, when I share with you that LISTENing to Your body is a game changer in the healing process, I am speaking from expertise and direct experience". Mission: A Healer in Every Household! For more great information to go to her weekly blog:  http://bowencollege.com/blog.  For tips on health & healing go to: https://www.drmanonbolliger.com/tips Follow: Manon Bolliger website  | Linktr.ee | Rumble | Gettr  | Facebook | Instagram | YouTube | Twitter | LinkedIn | Follow: Bowen College Inc. | Facebook | Instagram  | LinkedIn | YouTube | Twitter | Rumble | Locals ABOUT THE HEALERS CAFE: Manon's show is the #1 show for medical practitioners and holistic healers to have heart to heart conversations about their day to day lives. Subscribe and review on your favourite platform: iTunes | Google Play | Spotify | Libsyn | iHeartRadio | Gaana | The Healers Cafe | Radio.com | Medioq | Audacy | Follow The Healers Café on FB: https://www.facebook.com/thehealerscafe   Remember to subscribe if you like our videos. Click the bell if you want to be one of the first people notified of a new release. * De-Registered, revoked & retired naturopathic physician after 30 years of practice in healthcare. Now resourceful & resolved to share with you all the tools to take care of your health & vitality!  

Nesta edição, analisamos estratégias para enfrentar doenças silenciosas e simplificar o cuidado crónico. Começamos pelo alerta sobre a doença renal crônica no Brasil, que pode afetar 500 mil pacientes nos próximos cinco anos, destacando a urgência de exames simples como creatinina e albuminúria. Detalhamos os benefícios da monitorização contínua de glicose (CGM) no Diabetes Tipo 2, que permite ajustes comportamentais e melhoria na HbA1c sem novos fármacos. Por fim, abordamos no Radar a eficácia da polipílula tripla na prevenção de AVC recorrente, uma estratégia que privilegia a adesão e a segurança em pacientes complexos. Afya News. Informação médica confiável e atualizada no seu tempo.Fontes do episódio aqui:⁠https://portal.afya.com.br/podcasts/afya-news/01-05-2026

The National Health Laboratory Service has launched South Africa's first National Diabetes Dashboard. The HbA1c dashboard gives a near real-time national view of diabetes control using lab data updated within 48 hours. It comes as diabetes remains a leading cause of death in the country. We spoke to Dr. Siyabonga Khoza, Head of Academic Department at the National Health Laboratory Service (NHLS), Head of the Department of Chemical Pathology at the University of the Witwatersrand

What if illness was optional?Naveen Jain has built seven companies. He was on top of the world running Moon Express, the first private company ever granted permission to leave Earth orbit, with a $2.6 billion NASA contract to mine the moon, when his father was diagnosed with stage 4 pancreatic cancer and given three months to live.He got exactly that.That moment broke something open. Naveen walked away from space and started asking a different question: if we can land on the moon, why are we still finding cancer by a dentist running a finger across someone's gum?In this episode, Naveen sits down with Jessica to share the framework behind every company he builds: why this, why now, why me.That framework led him from helium-3 mining to founding Viome, the company now running 1.5 million tests, sitting on 400 quadrillion biological data points, and holding FDA Breakthrough Device designation for detecting stage 1 oral and throat cancer with 95% specificity.A stage 1 pancreatic cancer test launches in the next three months.Jessica and Naveen go deep on:The three questions every founder must answer before starting anythingWhy DNA testing companies are asking the wrong question, and what RNA reveals insteadThe 100 trillion microbes producing 99.9% of the genes expressed in your bodyHow a classified Los Alamos biological defense project became the foundation of ViomeWhy cancer immunotherapy works for 1/3 of patients, and what changes when you fix the gutThe double-blind data: HbA1c down 0.42 in 90 days, IBS reversal in 64% of patients, anxiety down 50%Building a culture where loyalty shifts from the founder to the missionWhy Naveen, at 66, still believes he owes a debt to his fellow humansThe advice he'd give every leader: dream so big people think you're crazyA masterclass in first-principles thinking, mission-driven leadership, and the radical idea that chronic disease isn't a feature of aging.It's a signal we've been ignoring.Truth Works is hosted by Jessica Neal, former Netflix CHRO, here to interrogate what actually works in leadership and life.If this conversation shifted how you think about your health, your work, or what you're capable of building, share it with someone who needs to hear it.

Fatty liver and insulin resistance form a dangerous loop driving diabetes, dementia, and colon cancer. Learn what causes this cycle, what happens when it keeps running, and how diet, fasting, the Mediterranean diet, and targeted supplements can break it for good. FEATURED PRODUCT The Good Poops Protocol — combining Liver Boost, Gut Powder, and Berberine Plus — directly targets both sides of the fatty liver and insulin resistance loop discussed in this episode. Liver Boost supports your liver's ability to process fats and manage detoxification, Berberine Plus has been shown to improve insulin sensitivity and lower pro-inflammatory cytokines, and Gut Powder addresses the digestive consequences — bloating, constipation, and gut dysfunction — that compound when this loop goes unchecked. Together, these three work on the liver, the blood sugar, and the gut simultaneously, which is exactly what this episode makes clear you need.

Jeremy Malecha is the founder of Biocanic, a tech-enabled platform built specifically for functional, integrative, and longevity medicine practitioners. In this episode, Jeremy pulls back the curtain on one of the most exciting intersections in modern health: artificial intelligence meets real-world patient data. He shares how his team ran a linear regression between Oura sleep scores and gut microbiome markers — and predicted his own sleep score to within a single point. The conversation digs into why more data doesn't automatically lead to better health outcomes, how Biocanic's Nexus analytics layer helps practitioners objectively demonstrate results (think VO2 max improvements, reduced toxin burden, improved HbA1c), and why the future of functional medicine is about synthesizing data down — not piling it higher. Freddie and Jeremy also explore the massive opportunity for solo FDN practitioners and large integrative clinics alike, covering real-world use cases from ketogenic mental health programs to integrative oncology and EBOO therapy. They get into the cost of the platform (starting at $75/month), lab integrations across 350+ providers including GI Map, Dutch, and Quest, and what it looks like when a clinic goes from siloed chaos to a single, unified health record. Whether you're navigating your own healing journey or running a clinic that wants to prove its outcomes and scale its impact, this conversation will change how you think about personalized medicine, AI in healthcare, and the future of the patient-practitioner relationship.   Episode Highlights [00:00] – Why healthcare is splitting into emergency care vs personalized optimization [03:17] – What Jeremy does building software for integrative and functional practitioners [04:25] – The data overload problem wearables, labs, and too much information [06:51] – Using AI to uncover correlations between biomarkers and real outcomes [09:07] – The future of predicting health outcomes with fewer tests [11:20] – Why more data alone doesn't improve health [13:39] – Moving from testimonials to measurable outcomes in medicine [18:12] – How practitioners can prove results and stand out in a crowded space [20:35] – The post-pandemic shift toward taking ownership of your health [22:57] – Why AI can't replace human connection in healing [25:35] – Disrupting healthcare from the outside not within [30:29] – The importance of proper training in functional medicine [33:23] – Measuring effectiveness of therapies like detox and advanced modalities [37:33] – Why foundational habits still matter more than tools [45:02] – Why Biocanic avoids insurance and focuses on concierge care [47:58] – The future of patient-owned health data [54:14] – Integrative oncology and rebuilding the body after cancer [59:11] – Jeremy's personal health stack sauna, detox, and reducing carbs   Links & Resources The Biological Blueprint Program: https://www.beautifullybroken.world/ Biocanic: https://www.biocanic.com/request-a-demo/?am_id=frederick2598 Use code 10OFFTODAY for $10 off a month Get Silver Biotics: bit.ly/3JnxyDD — 30% off with Code: BEAUTIFULLYBROKEN CONNECT WITH FREDDIEWork with Me: https://www.beautifullybroken.world/biological-blueprintWebsite and Store: (http://www.beautifullybroken.world) Instagram: (https://www.instagram.com/freddie.kimmelYouTube: https://www.youtube.com/@beautifullybrokenworld Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Nurse Doza doesn't always eat lunch — but he never skips protein and animal fat. In this episode, he breaks down why he reaches for clean, 100% grass-fed beef jerky as his go-to midday snack, how the ingredients in Lineage Provisions meat sticks — grass-fed beef, organic apple cider vinegar, and salt — actively support blood sugar, reduce inflammation, and help with weight management. Because what you snack on matters more than you think. Featured Partner: Lineage Provisions Lineage Provisions delivers exactly what Nurse Doza looks for in a snack: 100% grass-fed beef made with just three clean ingredients — grass-fed beef, organic apple cider vinegar, and salt. No fillers, no seed oils, no inflammatory junk that undoes the work you're already putting into your health. Their grass-fed beef jerky and liver meat sticks are the snack Nurse Doza trusts when he skips lunch and still needs to keep his blood sugar stable, energy up, and inflammation down. If you vote with your dollar, vote for ingredients that actually work for your body.

Nesta edição, analisamos estratégias para enfrentar doenças silenciosas e simplificar o cuidado crónico. Começamos pelo alerta sobre a doença renal crônica no Brasil, que pode afetar 500 mil pacientes nos próximos cinco anos, destacando a urgência de exames simples como creatinina e albuminúria. Detalhamos os benefícios da monitorização contínua de glicose (CGM) no Diabetes Tipo 2, que permite ajustes comportamentais e melhoria na HbA1c sem novos fármacos. Por fim, abordamos no Radar a eficácia da polipílula tripla na prevenção de AVC recorrente, uma estratégia que privilegia a adesão e a segurança em pacientes complexos. Afya News. Informação médica confiável e atualizada no seu tempo.Fontes do episódio aqui:⁠https://portal.afya.com.br/podcasts/afya-news/01-05-2026

Ever wished continuous glucose data didn't require needles, adhesives, or a prescription? We sit down with Sabih Chaudhry, PhD, founder of AFON Technology, to unpack GlucoWare—a wrist-worn, noninvasive glucose wearable that uses low-power RF signals to read blood in near real time. Instead of piercing the skin, the device couples with your wrist, wakes every five minutes, pings a tiny signal, processes the reflection in under 200 milliseconds, and sends the data to your phone before going back to sleep. The result: familiar CGM-style insights without the interstitial lag, skin-tone limitations, or daily hassles.We explore the journey from a rough “antenna and saline” lab hack to a robust, manufacturable design tested in environmental chambers and on robotic arms. Sabih explains how the team tackled motion noise, temperature swings, and material choices, all while building for scale and regulatory approval. We compare RF spectroscopy to optical approaches, discuss accuracy targets, and outline a roadmap aimed at non–insulin-dependent type 2 users first, with CE marking in sight and the FDA pathway running in parallel. Along the way, we dig into fundraising lessons, the choice to work with high-net-worth investors, and the newly inked partnership with a global manufacturer.Beyond the tech, the conversation lands on impact. A painless, over-the-counter path to real-time glucose could help more people see spikes after meals, personalize diet and exercise, and improve time-in-range—key steps toward lowering HbA1c and reducing complications that strain health systems. The design leans fashion-forward to remove stigma, while the app mirrors clinical conventions so clinicians and users can speak the same language. Looking ahead, AFON's modular electronics hint at future biomarkers—lactate, ketones, alcohol—and a smaller form factor suitable for kids, all pointing toward a smarter, more humane wearables era.If you care about metabolic health, diabetes innovation, or the next leap in consumer-friendly biosensing, this one's worth your queue. Subscribe, share with a friend who watches their glucose, and leave a review telling us what biomarker you want measured next.https://afontechnology.com/New episodes every Tuesday & Thursday. Subscribe so you don't miss one.Continue this conversation on Substack: https://robertlufkinmd.substack.comLies I Taught In Medical School — Free sample chapter: https://www.robertlufkinmd.com/lies/Web: https://www.robertlufkinmd.comYouTube: https://www.youtube.com/robertlufkinmdX: https://x.com/robertlufkinmdInstagram: https://www.instagram.com/robertlufkinmd/TikTok: https://www.tiktok.com/@robertlufkinLinkedIn: https://www.linkedin.com/in/robertlufkinmd/

Welcome to Ozempic Weightloss Unlocked, where we dive into the latest news on Ozempic from medical breakthroughs to real-life health impacts.Semaglutide, the active ingredient in Ozempic, is showing surprising mental health perks. A large study by researchers from the University of Eastern Finland, Karolinska Institutet, and Griffith University, published in The Lancet Psychiatry, found users had 42 percent fewer psychiatric hospital visits and 44 percent lower depression risk during treatment. Anxiety dropped 38 percent, substance use disorders fell 47 percent, and suicidal behavior risks decreased too. Science Daily reports these benefits may stem from lifestyle changes or direct brain effects.On the innovation front, Eli Lilly's oral pill orforglipron outperformed oral semaglutide in a 52-week phase three trial with 1698 adults with type two diabetes. Science Alert details how orforglipron cut blood sugar more, dropping HbA1c by 1.71 to 1.91 percent versus 1.47 percent, and spurred greater weight loss of 6.1 to 8.2 kilograms compared to 5.3 kilograms. Though more side effects like nausea led to higher dropouts, it's a promising needle-free rival.Stopping Ozempic? A Cleveland Clinic study of nearly eight thousand patients in Diabetes, Obesity and Metabolism challenges rebound fears. Those treated for obesity lost 8.4 percent body weight before stopping and regained just 0.5 percent after one year. Many restarted meds, switched treatments, or adopted lifestyle changes, with 45 percent maintaining or losing more weight.Heart and kidney wins continue: Johns Hopkins Public Health notes GLP-one drugs cut five-year risks of heart attacks and end-stage kidney disease by 15 percent in type one diabetes patients.Exercise matters too. Outside Online highlights a study where aerobic activity preserved muscle during 29-pound average losses on GLP-ones.Long-term, these drugs boost metabolic health, reduce inflammation, and may extend longevity via sustained weight loss, per Health Central and experts like James Hill from the University of Alabama.Real users report two-thirds fewer cravings, per 2026 data from engineering Cambridge.Thanks for tuning in, listeners. Subscribe for more updates. This has been a Quiet Please production, for more check out quietplease.ai. Some great Deals https://amzn.to/49SJ3QsFor more check out http://www.quietplease.aiThis content was created in partnership and with the help of Artificial Intelligence AI

Jay: After a diagnosis of Stage III kidney disease in 2018, I committed to a whole-food, plant-predominant diet, which includes seafood two to three times a week. The results were encouraging, as my kidney function and lipid profile improved dramatically. The switch also resulted in a 25-pound weight loss. When Rondi began intermittent fasting in 2020, I saw her positive results and began eating in an 18-6 or 19-5 window. I lost another 10 pounds and experienced an improvement in my HbA1c; I was no longer pre-diabetic. Three years ago, I transitioned to a one-meal-a-day regimen to get our eating schedules more in synch. Unless dining out with friends, we eat once each day at about 4 pm. My kidney filtration rate and creatinine reading have actually improved, which surprised my primary care doctor at my most recent annual physical. My nephrologist, who is also an IF devotee, took me off high blood pressure medicine six months ago, another very positive step. Intermittent fasting has improved my health in numerous measurable ways, and I will keep this eating pattern for the rest of my life. Rondi: In 2020, after a lifetime of working hard to keep my weight within the normal range, I discovered intermittent fasting. I quickly transitioned into a one-meal-a-day lifestyle. That meal normally consists of seafood, green vegetables, and usually a small dessert. Gradually, over several years, my weight came down to 135 pounds. My heaviest weight was 192, so my total weight loss was 57 pounds. I still have to watch my carb intake. Intermittent fasting changed my life, and I will be an OMAD-er for the rest of my life. Graeme's Links to connect with me directly.Please  Come and Join Our Patreon Community At the Link Belowwww.patreon.com/thefastinghighway.Sign up for a month or stay for a year, check it out, and get all the content. Your first step to excellent support and accountability is right here. I don't know of any hands-on support online for the cost that's as good as our Patreon members' community, and I urge you to check it out. All it's going to cost you is five dollars to access our whole library, including a free copy of my audiobook The Fasting Highway, join our Zoom talk with me directly, and meet other fasters sharing the same wins and struggles as you.To Book a Zoom Call With Graeme One-on-One, Please Go Here www.thefastinghighway.com Click on Get help, get coaching to work with me one-on-one.To Read My Book, The Fasting Highway, go to Amazon or any good book seller. To Listen to My Audio Book Apple Books or many Audio Book Platforms Free on Joining The Patreon Community To be a guest on the show, please go to www.thefastinghighway.com, click on listen to the podcast, and follow the "how to be a guest" prompt.To find everything in one place go to the website www.thefastinghighway.comDisclaimer - All views are those of the host and guest and should not be taken as medical advice. Please consult your doctor before starting any health plan.

Ever been told your blood tests are “normal”, but you’re still exhausted, flat, foggy, struggling with weight changes, or just not feeling like yourself? In this episode of The Nutrition Couch, Leanne and Susie unpack the difference between normal and optimal blood test results, and why women need to look beyond a quick “everything’s fine” from the doctor. They break down the key markers worth tracking over time, including glucose, HbA1c, ferritin, vitamin D, cholesterol, thyroid, and estrogen, especially for women in their 30s, 40s and beyond. They also dive into a new warning linked with GLP-1 medications, including how appetite suppression can reduce diet quality and increase the risk of nutrient deficiencies if you are not actively protecting your intake. Plus, they review a high-protein granola topper and answer a listener question on the healthiest takeaway options. In this episode, we cover: Why normal blood tests are not always optimal The blood markers women should track over time Low ferritin, fatigue, brain fog and poor exercise tolerance Glucose, HbA1c and the early signs of insulin resistance Vitamin D, cholesterol, thyroid and estrogen changes to watch Why women in perimenopause and menopause need to pay closer attention The new GLP-1 nutrient deficiency concern Why eating less can still mean poor nutrition Product review: Coastal Crunch Protein Crunch Listener question: the healthiest takeaway choices If you’ve ever felt dismissed by “normal” results, this episode will help you ask better questions and understand what to look at more closely.See omnystudio.com/listener for privacy information.

Dr. Marbas outlines essential lab tests and special panels for vegans, including CBC, B12, vitamin D, omega-3s, iron, and inflammation markers. #VeganHealth #PreventiveLabs #NutritionTracking #WellnessCheck

In this episode of the *Innovations and Clinical Implementation* podcast recorded at LongevityFest, hosts Tom Blue and Chris D'Adamo discuss the rapid evolution of epigenetic testing with Ryan Smith. Ryan Smith is the founder and global head of research and development at TruDiagnostic, a CLIA-certified lab and health data company that has built one of the world's largest private epigenetic databases to advance the measurement of biological aging. The discussion traces the 140% year-over-year growth in consumer interest regarding biological age and explores how TruDiagnostic utilizes AI to interpret over 1.3 million DNA methylation sites to validate longevity interventions in clinical trials. Smith previews the upcoming release of "methylation risk scores" that can predict the onset of diseases like COPD and Lyme disease, and details the development of "Epigenetic Biomarker Proxies" (EBPs) intended to eventually replace traditional labs by deriving thousands of metrics—such as HbA1c, CRP, and environmental toxins—from a single finger stick.   For access to episode resources, click HERE.

Novo Nordisk's new drug CagriSema has outperformed Ozempic in a recent Phase III trial for type 2 diabetes patients, according to Clinical Trials Arena. In the REIMAGINE 2 study, CagriSema reduced HbA1c levels by 1.91 percentage points and achieved 14.2 percent weight loss after 68 weeks, compared to 1.76 percentage points and 10.2 percent with Ozempic. No weight loss plateau occurred with CagriSema, and 43 percent of patients lost at least 15 percent of their body weight. Martin Holst Lange, Novo Nordisk's executive vice president and chief scientific officer, stated that combining semaglutide and cagrilintide delivers superior blood glucose control and weight reduction.Researchers are urging a more holistic approach to weight loss amid the Ozempic era, as reported by Medical Xpress on February 3. Experts like Martin Binks and Raedeh Basiri from George Mason University note that GLP-1 drugs such as Ozempic cause rapid weight loss but can lead to nutrient deficiencies, muscle loss, and struggles without proper nutrition, exercise, and psychological support. Many patients receive only prescriptions without multidisciplinary care, and access remains limited by cost and insurance gaps. Binks predicts broader availability with upcoming pill forms.A study highlighted by Science Daily on January 29 warns of rapid weight regain after stopping drugs like Ozempic, with people regaining about 0.4 kilograms per month, often faster than with diet and exercise alone. Heart health and diabetes risk improvements also reverse quickly, emphasizing the need for long-term strategies beyond medication.Oprah Winfrey has shared her experiences with GLP-1 medications, similar to Ozempic, in recent interviews covered by AOL and other outlets. At 71, she regrets not using them sooner, saying they silenced the food noise in her head and helped her view obesity as a disease, not a personal failure. She gained 20 pounds after stopping briefly but now sees these drugs as a lifelong tool, like blood pressure medication, and encourages others without shame.These developments show evolving options and cautions in weight loss treatments. Listeners, thanks for tuning in, please subscribe, and remember, this episode was brought to you by Quiet Please podcast networks. For more content like this, please go to Quiet Please dot Ai. Come back next week for more.Some great Deals https://amzn.to/49SJ3QsFor more check out http://www.quietplease.aiThis content was created in partnership and with the help of Artificial Intelligence AI

In this episode, Dr. Jessica Shepard, board-certified OB/GYN and Chief Medical Officer of Hers, shares that the FDA just removed the black box warning on hormone replacement therapy after 23 years. We discuss what actually happened with the WHI study that created all the fear around estrogen and breast cancer, and why the research never actually supported that narrative.Dr. Shepard explains why you shouldn't wait until menopause to start the HRT conversation and how starting in your perimenopausal years can make all the difference for long-term health. Dr. Shepard shares the essential labs she runs on patients including ApoB, HbA1c, and thyroid optimization, plus the longevity metrics women should be tracking.We also get into supplement recommendations including why she recommends 10 grams of creatine daily, the role of inflammation in aging, and how estrogen is naturally anti-inflammatory which is why women see increased cardiovascular risk and metabolic dysfunction after menopause.Kayla's social + website:Instagram:  kaylabarnesTikTok:  femalelongevityTwitter: https://x.com/femalelongevityWebsite: https://www.kaylabarnes.comSpotify: https://open.spotify.com/show/4OLWWn2...Apple: https://podcasts.apple.com/us/podcast...Follow Her Female Protocol: https://www.protocol.kaylabarnes.comDr. Jessica Shepherd's social + website:Website: https://www.jessicashepherdmd.com/Instagram: https://www.instagram.com/jessicashepherdmd/Transform Your Health: https://eudemonia.net/?utm_source=podcast&utm_medium=kayla-podcast&utm_campaign=jessica-shepherd

Dr. Marcus Pinto joins us to break down how to evaluate new numbness, tingling, and foot pain with simple bedside tests that separate true neuropathy from common mimics. Practical steps, key red flags, and a high-yield lab strategy give primary care and non-neuro clinicians a clear path forward.• distinguishing positive vs negative symptoms• using location and constancy to sort causes• recognizing stocking–glove vs focal patterns• bedside “eyes closed” test for persistence• neuropathic pain descriptors vs mechanical pain• autonomic clues: gastroparesis and orthostatic hypotension• gait, heel–toe walking, and reflex triage• light touch, pinprick, temperature, and vibration methods• when vibration beats proprioception• ulcers as a marker of severity and healing issues• chronicity clues: atrophy, high arches, hammered toes• targeted labs: CBC, CMP, HbA1c, lipids, B12, B1, B6, copper, zinc• when to order EMG and what to avoid• metabolic health and neuropathy progressionFind our work at theneurotransmitters.com and on X at neuro_podcastSend us a textUnderstanding Hypophosphatemia: Recognition, Diagnosis, and TreatmentEndocrine experts distinguish Hypophosphatemia from osteoporosis & osteomalaciaListen on: Apple Podcasts SpotifySupport the show Check out our website at www.theneurotransmitters.com to sign up for emails, classes, and quizzes! Would you like to be a guest or suggest a topic? Email us at contact@theneurotransmitters.com Follow our podcast channel on

Metabolic health impacts far more than weight — it influences your hormones, inflammation levels, energy, and long-term risk for chronic disease. In this episode of Get Well Better by The Lanby, Taylor Fazio, Wellness Advisor, breaks down what metabolic health really means, why most Americans are metabolically unhealthy, and the everyday habits that can dramatically improve insulin sensitivity and overall health.On this “One Take on One Take” episode:Tip 1: Optimize nutrition by prioritizing fiber, reducing ultra-processed foods, and building balanced meals to support stable blood sugar and reduce inflammation.Tip 2: Build movement into your day — especially strength training — since muscle is one of the most important sites for glucose storage and insulin sensitivity.Tip 3: Use data to personalize your health journey: track key labs (fasting insulin, glucose, HbA1c) and consider a CGM to understand your unique glucose response and improve metabolic flexibility.

Leg weakness, burning when walking, wobbling knees, or foot pain are not signs of aging. They are often early warnings of insulin resistance and metabolic dysfunction, which silently damages muscle, nerves, and circulation long before diabetes is diagnosed. Your legs are meant to be the body's largest blood sugar sponge. When insulin resistance develops, glucose cannot enter muscle cells efficiently, leading to muscle fatigue, inflammation, fat infiltration, nerve damage, and poor circulation. Common warning signs include: Heavy or tired legs while walking Burning or cramping muscles Balance issues and slower gait Difficulty standing from a chair Tingling, numbness, or cold feet Key labs that reveal the problem: Fasting insulin (optimal: 3–6) HbA1c (optimal: 5.2% or lower) Fasting glucose (70–90 mg/dL) Triglycerides under 100 HDL over 60 Triglyceride-to-HDL ratio under 1.5 The 7-step protocol to restore leg strength: Stop eating at least 3 hours before bed Strength train legs twice per week Eat 30–40g of high-quality protein per meal Lower carbs, eliminate snacking, and walk after meals Walk daily to improve circulation Support nerves with sleep, B vitamins, grounding, and red light therapy Prioritize deep, consistent sleep Ben emphasizes that leg strength is metabolic protection, not vanity, and that fixing insulin resistance can rapidly restore strength, balance, and energy.

What if the most powerful health checkup you ever had happened at your kitchen table, not a clinic? We sit down with Dr. Natasha Milinkovic, a UK physician who moved from the front lines of vascular surgery and emergency medicine to the leading edge of preventive care, to explore how lab‑grade at‑home blood testing and intelligent coaching can change outcomes before a crisis hits.We start with the problem he saw repeatedly: people arriving late with preventable chronic disease. That urgency drives a practical roadmap for what to measure and why. You'll hear a clear breakdown of high‑value biomarkers—HbA1c for glucose trends, ApoB and the ApoB to ApoA1 ratio for cardiovascular risk, and thyroid markers for therapy tuning—and why total cholesterol alone often misleads. Tosh explains how accuracy is maintained through CLIA‑accredited labs and transparent methods, addressing trust in a post‑Theranos world. We also dig into biological age: how markers like hs‑CRP, HbA1c, and sex hormones push it up or down, and the specific lifestyle levers that can nudge it younger over the next 90 days.Then we open the hood on Sai, an AI longevity expert trained on a clinician‑curated knowledge base. Instead of scraping the noisy web, Sai reads your longitudinal labs, medications, and context to deliver personalized, evidence‑based guidance. Think trend detection for creeping glucose, stubborn ApoB, or hidden inflammation—and concrete next steps that you can take today. Looking ahead, Tosh shares what's next: home hardware that brings instant panels into your routine and a vision of predictive health where alerts trigger action long before symptoms do.If you want to cut through hype, track the markers that matter, and pair credible data with smart coaching, this conversation will give you the playbook. Subscribe, share with a friend who's optimizing their health, and leave a review with the one biomarker you plan to track this year.Note: I am an advisor to Siphox but I only advise those companies whose products I would use for myself and family.https://siphoxhealth.com/lufkinFASTING CHALLENGE: https://robert-lufkin.mykajabi.com/fast?ref=RLLies I Taught In Medical School : Free sample chapter- https://www.robertlufkinmd.com/lies/Complete Metabolic Heart Scan (LUFKIN20 for 20% off) https://www.innerscopic.com/Fasting Mimicking Diet (20% off) https://prolonlife.com/Lufkin At home blood testing (20% off) https://siphoxhealth.com/lufkin Web: https://robertlufkinmd.com/X: https://x.com/robertlufkinmdYoutube: https://www.youtube.com/robertLufkinmdSubstack: https://robertlufkinmd.substack.com Instagram: https://www.instagram.com/robertlufkinmd/LinkedIn: https://www.linkedin.com/in/robertlufkinmd/TikTok: https://www.tiktok.com/@robertlufkinThreads: https://www.threads.net/@robertlufkinmdFacebook: ...

This episode covers: • Trump Drug Pricing Deals and Access to Longevity Medications New drug-pricing agreements announced under President Donald Trump aim to lower the cost of high-priced prescription drugs through negotiated rebates and pricing pressure on major pharmaceutical companies. Early reporting suggests these changes could affect cardiometabolic and longevity-relevant medications, including GLP-1 diabetes and obesity drugs. Dave explains why the real question is not headline savings, but whether lower prices actually reach patients at the pharmacy counter. He breaks down how affordability shapes real-world access, adherence, and long-term prevention strategies, and why policy decisions can matter more than new mechanisms when it comes to sustainable longevity care. Source: https://longevity.technology/news/trump-sets-new-drug-pricing-deals-with-big-pharma/ • 5:2 Intermittent Fasting Outperforms Daily Dieting on Metabolic Health A controlled study compared three popular strategies in people with obesity and type 2 diabetes: 5:2 intermittent fasting, time-restricted eating, and continuous daily calorie restriction. All approaches improved weight and HbA1c, but the 5:2 protocol produced larger reductions in fasting glucose, triglycerides, and insulin resistance. Dave explains why periodic restriction can outperform constant dieting, how to structure fasting days without tanking performance, and how to pair intermittent fasting with CGM data and training schedules for better metabolic flexibility and long-term health. Source: https://www.sciencedaily.com/releases/2025/07/250715043351.htm Full paper: https://www.nature.com/articles/s41598-025-32673-9 • Cocoa's Theobromine Linked to Slower Epigenetic Aging New research highlighted by Aging-US suggests that theobromine, a bioactive compound found in cocoa, is associated with epigenetic markers of slower biological aging. Dave breaks down what epigenetic aging clocks actually measure, why this finding adds credibility to cocoa's cardiometabolic benefits, and why most chocolate products cancel out the upside with sugar and ultra-processing. He explains how to think about food-derived bioactives without turning them into hype-driven anti-aging shortcuts. Source: https://www.aging-us.com/news-room/theobromine-from-cocoa-linked-to-slower-biological-aging • Organ-Specific Biological Age Clocks Predict Disease Risk More Accurately A large Nature study built biological aging clocks for individual organs using blood-based proteomics, showing that organ-specific aging predicts disease and mortality better than a single “bio age” number. Dave explains why you can be biologically young overall but still have an aging brain, arteries, or kidneys, and how this reframes longevity from generic anti-aging to targeted organ protection. He explores how sleep, blood pressure, glucose control, and exercise map differently to different organs, and why precision aging metrics are the future of prevention. Source: https://www.nature.com/articles/s43587-025-01016-8 • Copper Peptides and the Rise of Skin Longevity Copper peptides like GHK-Cu are moving from niche skincare into serious longevity conversations. Human data show strong effects on collagen synthesis, barrier repair, and wound healing, in some cases outperforming traditional retinoids. Dave explains why skin is not just cosmetic but a key immune and environmental interface, how copper peptides fit into repair-focused protocols, and why cycling repair and stress mirrors smarter approaches to training and recovery across the body. Source: https://www.vogue.com/article/copper-peptides Auro Wellness Copper Peptide with Discount (click on skincare and scroll to Copper Peptide): https://aurowellness.com/pages/dave All source links provided for direct access to the original research and reporting. This episode is designed for biohackers, longevity seekers, and high-performance listeners who want practical strategies grounded in real science and real-world constraints. Dave Asprey translates emerging research, policy shifts, and clinical data into actionable upgrades for metabolism, fasting, biological age tracking, skin health, and long-term prevention. New episodes every Tuesday, Thursday, Friday, and Sunday. Keywords: Trump drug pricing deals, prescription drug affordability, GLP-1 access, cardiometabolic medications, longevity policy, intermittent fasting 5:2, intermittent energy restriction, time restricted eating study, insulin sensitivity improvement, metabolic flexibility fasting, theobromine cocoa aging, epigenetic aging markers, biological age clocks, organ specific aging, proteomics longevity research, brain age dementia risk, vascular aging, copper peptides GHK-Cu, skin longevity protocols, collagen synthesis skincare, evidence-based biohacking news, longevity science updates Thank you to our sponsors! - HeartMath | Go to https://www.heartmath.com/dave to save 15% off. -Generation Lab | Go to http://generationlab.com/, use code Dave20 for $20 off, and see what your body's really doing behind the surface. Resources: • Subscribe to my weekly newsletter: https://substack.daveasprey.com/welcome • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 - Trailer0:19 - Story 1: Trump's Drug Price Deals 2:33 - Story 2: Fasting Reality Check 4:35 - Story 3: Chocolate and Biological Age 6:11 - Substack Update7:30 - Story 4: Organ-Specific Aging 9:05 - Story 5: Copper Peptides for Skin 11:02 - Weekly Wrap-Up See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

This conversation covers a range of topics related to health, nutrition, and dietary practices, focusing on hydration, sodium intake, autoimmune conditions, and the implications of various diets such as keto and carnivore. The speakers discuss the importance of protein, the role of metabolic flexibility, and the nuances of interpreting health metrics like HbA1c and CAC scores. They also emphasise community engagement and the value of educational resources for a better understanding of the dietary impacts on health.Chapters00:00 Q&A and Practical Advice01:38 The Sodium Paradox: Understanding Sodium Intake and Health04:40 Dietary Strategies for Autoimmune Conditions07:40 Exploring the Benefits of Carnivore Diets09:41 Understanding HbA1c and Its Implications13:23 Nutritional Protocols and Their Efficacy15:55 Metabolic Flexibility: The Body's Energy Regulation17:47 Cortisol and Leptin: Hormonal Balance in Health19:04 The Role of Protein in Diets22:26 Evaluating CAC Scores and Dietary Impact25:35 Community Engagement and Learning Opportunities

This episode covers: • FDA Loosens Supplement Warning Labels The FDA is considering a rule change that would allow supplement companies to include the DSHEA disclaimer only once per package rather than next to every claim. Dave explains why fewer visible warnings could make marketing look more like medical claims, and why biohackers should treat labels as advertising rather than evidence. He shares how to protect yourself now: add one variable at a time, run baseline labs, and rely on data instead of packaging. Source: https://www.nbcnews.com/health/health-news/fda-supplements-warning-label-rule-change-rfk-jr-rcna249321 • Quantum Sensors for Early Heart Attack Detection Mayo Clinic is testing a contactless heart-monitoring system called CardiAQ using quantum magnetic sensors and AI noise filtering. The device reads subtle electromagnetic signatures from the heart and compares them to invasive angiography. Dave breaks down why earlier detection of ischemia could shift heart care from reactive treatment to proactive screening — and why building baseline metrics like VO₂max, blood pressure and HRV today will pay off when next-gen diagnostics arrive. Source: https://www.sandboxaq.com/press/sandboxaq-collaborates-with-mayo-clinic-on-novel-cardiac-diagnostics • Sauna Detox for MicroplasticsEmerging research shows that sweating meaningfully removes plastic-related chemicals like BPA and phthalate metabolites from the body, often more efficiently than blood or urine alone. Sauna use amplifies this effect by increasing circulation, mobilizing stored toxins from tissues, and accelerating sweat-based excretion. When you combine regular heat exposure with reduced environmental plastic contact, you create a powerful detox strategy that targets a chemical burden once thought unavoidable. Dave breaks down how sauna protocols can support toxin elimination, improve cardiovascular resilience, strengthen autonomic balance, and help counteract the metabolic and hormonal disruptions linked to microplastics in modern life.Source: https://superage.com/can-you-sweat-out-microplastics-in-the-sauna/ • Psychedelics and Longevity Biomarkers Bryan Johnson treated a guided psilocybin experience as a structured longevity experiment, collecting nearly 250 biomarkers including CGM, stress markers, HRV and Kernel brain imaging. The experiment revealed a surprising metabolic change: mean glucose dropped 8 percent, variability fell 11 percent, and estimated HbA1c moved from 4.7 to 4.4 — similar to months of metformin but after a single session. Dave explores the emerging idea that neuroplastic events might influence glucose regulation through brain-pancreas signaling, while emphasizing the need for supervised, legal use and proper clinical trials. Source: https://www.businessinsider.com/bryan-johnson-trip-on-mushrooms-five-hours-live-2025-12 • A Mitochondrial Protein that Extends Mouse Lifespan Researchers boosted the mitochondrial protein COX7RP and extended mouse lifespan by ~6.6 percent while improving insulin sensitivity, lipid handling, endurance and liver fat metabolism. COX7RP supports formation of mitochondrial “supercomplexes,” improving respiratory efficiency and ATP generation. Dave explains how this reinforces lifestyle levers — strength training, aerobic capacity, stabilizing blood sugar — as tools that likely preserve supercomplex architecture and mitochondrial resilience. Source: https://www.eurekalert.org/news-releases/1109082 All source links provided for direct access to the original research and reporting. This episode is designed for biohackers, longevity seekers and high-performance listeners who want practical strategies rooted in cutting-edge science. Dave Asprey translates emerging research into actionable upgrades for your biology — from metabolism and mitochondria to nervous system health, detox, and prevention. New episodes every Tuesday, Thursday, Friday, and Sunday. Keywords: FDA supplement rule change, supplement warning labels, DSHEA disclaimer removal, supplement regulation risks, quantum cardiac scanner, Mayo Clinic heart attack detection, AI heart monitoring, early ischemia detection technology, sauna detox evidence, sweating out toxins research, BPA phthalate sweat studies, microplastics sauna myth, Bryan Johnson psilocybin experiment, psychedelic longevity research, psychedelic metabolic reset, glucose control psychedelics, HbA1c psilocybin results, continuous glucose monitor insights, mitochondria lifespan research, COX7RP protein aging study, mitochondrial supercomplex benefits, ATP energy output aging, metabolic flexibility longevity, biohacking news update, anti-aging science breakthroughs, evidence-based longevity tools, biological age biomarkers Thank you to our sponsors! -BEYOND Conference 2026 | Register now at https://beyondconference.com/ -BodyGuardz | Visit https://www.bodyguardz.com/ and use code DAVE for 25% off. Resources: • Subscribe to my weekly newsletter: https://substack.daveasprey.com/welcome • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 - Intro 0:18 - Story 1: FDA Supplement Label Changes 1:43 - Story 2: CardiAQ Heart Scanner 2:59 - Story 3: Saunas and Microplastics 4:58 - Story 4: Psychedelics and Blood Sugar 8:22 - Story 5: Mitochondrial Longevity Research 10:29 - Weekly Wrap-Up See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In this powerful and paradigm-shifting conversation, Darin Olien sits down with Dr. Mindy Pelz to dismantle everything we've been told about menopause, hormones, aging, and women's power. This is not a conversation about "fixing" women — it's about understanding a profound neurological, biological, and evolutionary transition that has been misunderstood, pathologized, and silenced for decades. Together, they explore why menopause is not the end of vitality, but the beginning of leadership, clarity, and sovereignty — and why reclaiming this transition could fundamentally reshape families, culture, and the future of women's health.     What You'll Learn (with Full Timecodes) 00:00:00 – Welcome to SuperLife: Why this episode matters for everyone, not just women 00:01:05 – The hidden cost of modern living: Plastics, endocrine disruption, and invisible hormonal stress 00:02:47 – Introducing Dr. Mindy Pelz: Why this conversation goes deeper than anything online 00:03:17 – Why women were excluded from medical research for decades 00:05:26 – The shocking pattern Dr. Pelz saw in women in their 40s: When life looks perfect but feels unbearable 00:06:41 – The suicide and divorce statistics no one talks about 00:07:27 – Why menopause exists at all: The evolutionary mystery 00:08:55 – The Grandmother Hypothesis: Why post-menopausal women kept humanity alive 00:10:08 – The brain shift that makes women stop people-pleasing 00:11:31 – Aging, fear, and the cultural erasure of women's wisdom 00:13:10 – The female brain before vs. after menopause 00:15:13 – Darin's reflection on his mother and invisible female labor 00:16:06 – Why community, safety, and oxytocin matter more than willpower 00:18:00 – Carol Gilligan's research: When girls stop knowing what they want 00:19:32 – Menopause as an awakening — not a breakdown 00:21:24 – Why men must be part of this conversation 00:22:26 – Leadership, aging, and reclaiming relevance 00:24:18 – Family dynamics when identity shifts 00:25:33 – The problem with outsourcing menopause to hormone therapy alone 00:27:00 – How to communicate needs without blame or collapse 00:30:07 – Metabolic health, insulin resistance, and early menopause 00:31:16 – The one blood marker every woman over 40 must track (HbA1c) 00:34:45 – The Hormonal Hierarchy explained: Cortisol, insulin, sex hormones, oxytocin 00:37:44 – Menopause as a cultural rite of passage we never created 00:39:31 – Dementia, Alzheimer's, and the glucose-starved brain 00:40:23 – Why fasting is neuroprotective for women 00:42:35 – How fasting helps menopausal belly weight 00:44:36 – Why shame keeps women disconnected from their power 00:45:34 – Why puberty and menopause are happening earlier 00:46:21 – Big Pharma, fear narratives, and the HRT conversation 00:48:35 – Empowerment vs. outsourcing health 00:50:11 – Why society fears powerful, post-menopausal women 00:52:11 – Dr. Pelz's personal breaking point and nervous system reset 00:55:33 – Redefining work, marriage, and self-permission 00:58:37 – Resentment as a diagnostic tool 01:01:15 – Neuroplasticity, obstacles, and the hero's journey 01:03:16 – Why going through discomfort rewires the brain 01:04:23 – Integration: Menopause as rebirth, leadership, and collective healing 01:12:25 – Closing reflections and final takeaways     Thank You to Our Sponsors: Therasage: Go to www.therasage.com and use code DARIN at checkout for 15% off Bite Toothpaste: Go to trybite.com/DARIN20 or use code DARIN20 for 20% off your first order Caldera Lab: Experience the clinically proven benefits of Caldera Lab's clean skincare regimen and enjoy 20% off your order by visiting calderalab.com/darin and using code DARIN at checkout.     Join the SuperLife Community Get Darin's deeper wellness breakdowns — beyond social media restrictions: Weekly voice notes Ingredient deep dives Wellness challenges Energy + consciousness tools Community accountability Extended episodes Join for $7.49/month → https://patreon.com/darinolien     Find More From Dr. Mindy Pelz: Website: drmindypelz.com Instagram: @dr.mindypelz Follow her YouTube Channel Podcast: The Resetter Podcast Order her new book: Age Like a Girl     Find More from Darin Olien: Instagram: @darinolien Podcast: SuperLife Website: https://superlife.com Book: Fatal Conveniences     Key Takeaway: Menopause isn't a failure of the female body — it's the moment a woman's brain rewires for truth, leadership, and independence. When we stop trying to fix women and start understanding this transition, we don't just heal individuals — we change families, cultures, and the future.  

Program notes:0:37 Breast density knowledge outcomes1:37 Breast density notification and education2:37 Can't assess the import individually3:30 CV outcomes with tirzepatide4:30 HbA1c 8.45:30 GLP-1s have many benefits6:30 No difference in adverse events7:10 Covid vaccination in pregnancy8:10 20K women included9:10 Initial benefit is it durable?9:30 Complex regional pain syndrome treatment10:30 Using bisphosphonates for treatment11:33 Even light contact causes severe pain12:28 End

A long-term analysis of major prediabetes trials found that achieving remission or returning glucose levels to normal was associated with over a 50% reduction in cardiovascular death or heart failure, with durable benefits decades later; delaying diabetes without remission did not show similar benefit. A randomized trial in critically ill adults found no difference in 28-day mortality between ketamine and etomidate for intubation, though ketamine increased the risk of cardiovascular collapse. Finally, molecular data showed indoor tanning causes widespread DNA mutations linked to melanoma, reinforcing its carcinogenic risk.

View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter's Weekly Newsletter In this "Ask Me Anything" (AMA) episode, Peter tackles a wide-ranging set of listener questions spanning lifespan interventions, exercise, cardiovascular risk reduction, time-restricted eating, blood pressure management, hormone therapy, diagnostics, and more. Peter reveals the single most important lever for extending healthspan and lifespan, and explains how he motivates midlife patients using the Centenarian Decathlon framework. He discusses the importance of addressing high apoB and cholesterol even in metabolically healthy individuals with calcium scores of zero, how to manage high blood pressure, and how to accurately evaluate metabolic health beyond HbA1c. Additional topics include time-restricted eating, practical considerations around ultra-processed foods, nuanced approaches to HRT for women and TRT for men, and why early and expanded screening for chronic disease—colonoscopy, PSA, coronary imaging, low-dose CT—can be lifesaving. He also offers insights into treating prediabetes, crafting exercise programs for those short on time, and safely incorporating high-intensity training in older adults. If you're not a subscriber and are listening on a podcast player, you'll only be able to hear a preview of the AMA. If you're a subscriber, you can now listen to this full episode on your private RSS feed or our website at the AMA #78 show notes page. If you are not a subscriber, you can learn more about the subscriber benefits here. We discuss: Introducing a wide-ranging AMA: practical perspectives on lifespan interventions, metabolic health, diet, hormones, diagnostics, and more [2:45]; Why exercise is the most powerful single intervention for lifespan and healthspan [4:15]; How Peter motivates midlife patients to prioritize exercise [6:00]; Why lifespan and healthspan should not be treated as competing priorities and how choosing sustainable interventions benefits both [9:30]; Why high apoB deserves treatment even in a metabolically healthy patient with a CAC score of zero [14:00]; Managing hypertension: ideal targets for blood pressure, lifestyle levers, and why early pharmacology matters [18:15]; Assessing metabolic health beyond HbA1c: fasting insulin, triglycerides, lactate, zone 2, and more [23:30]; How to avoid common self-sabotaging patterns by choosing sustainable habits over extreme health interventions [26:00]; Time-restricted eating: minimal effect beyond calorie control, implications for protein intake, and practical considerations for implementing it [28:00]; Ultra-processed foods: definitions, real-world risks, and practical guidelines for smarter consumption [30:30]; How women should prepare for menopause and think about hormone replacement therapy: early planning, symptom awareness, and guidance on HRT [36:45]; Testosterone replacement for aging men: indications, benefits, and safe clinical management [39:45]; Why Peter recommends earlier and more aggressive screening tests than guidelines suggest: colonoscopies, coronary imaging, PSA, Lp(a), and low-dose CT scans, and more [43:30]; Full-body MRI screening: benefits, limitations, potential false positives, and the importance of physician oversight [47:15]; Prediabetes: individualized treatment strategies using tailored combinations of nutrition, sleep, and training interventions [51:00]; Time-efficient training plans for people with only 30 minutes per day to exercise [53:00]; How to safely introduce high-intensity exercise for older adults [55:00]; Timed dead hangs and ripping phone books: a playful look at Peter's early attempts to impress his wife [57:15]; Peter's carve out: The Four Kings documentary about a golden era of boxing [1:01:15]; and More. Connect With Peter on Twitter, Instagram, Facebook and YouTube

What if you thought you were doing the right things and invincible, and then…a heart attack happens? That's exactly what my guest Cindy experienced. She had been trying to eat ‘clean keto' and was feeling she had more energy with weight loss, and then a heart attack came out of the blue. That's how her life as she knew it, changed when she came out of the surgery room and was prescribed 5 meds.   Join me in this episode as we hear of Cindy's plant-based diet journey, the changes she experienced and her key piece of takeaway advice for those wanting to start or continue eating plant-based. The best part? I followed up with Cindy and two years later eating plant-based, she has come off of nearly all her meds and her HbA1c level is even lower!     Contact -> healthnow@plantnourished.com Learn -> www.plantnourished.com Join -> Plant-Powered Life Transformation Course: www.plantnourished.com/ppltcourse Connect with Community -> www.facebook.com/groups/beginnerplantbaseddietsuccess Get Free 15-Minute Strategy Call -> www.plantnourished.com/strategycall Free Resource -> Quick Start Grocery Guide for Plant-Based Essentials: www.plantnourished.com/groceryguide     Have a question about plant-based diets that you would like answered on the Plant Based Eating Made Easy Podcast? Send it by email (healthnow@plantnourished.com) or submit it by a voice message here: www.speakpipe.com/plantnourished       [Plantbased Eating, Plant Based, Heart Attack, Blood Sugars, Blood Glucose Control, Prediabetes, Diabetes, Keto, Plantbased Transition, Heart Health, Heart Disease, Weight Loss, Whole Foods, Lose Weight, Drop Pounds]

Topics We Cover: 00:00 – New data from Harvard/Mass General may classify nearly 70% of adults as having obesity 03:00 – A new oral triple agonist shows record-setting absorption rates 07:00 – Fractal Health's Revita procedure: weight maintenance after stopping GLP-1s 12:00 – Zepbound vial prices drop (full breakdown by dose) 16:00 – Dave's personal experience switching off Mounjaro and intense hunger return 22:00 – Novo Nordisk's EVOKE/EVOKE+ Alzheimer's trial: what the data really means 29:00 – Why GLP-1 neurological research is just getting started 33:00 – Updates on access, partners, and major news coming soon for Medicare patients If you're on Wegovy, Mounjaro, Zepbound, Saxenda, Trulicity, or compounded versions, this episode gives you the insight and context you need to have more competent and confident conversations with your doctor. Bullet Point Summary of the Podcast Episode New Obesity Measurement Data (Harvard/Mass General Study) Harvard and Mass General propose adding waist circumference to BMI to better diagnose obesity. Traditional BMI misses key factors like muscle mass and body composition. Using the updated measure, Americans classified as obese jumps from ~43% to almost 69%. This means 7 out of 10 U.S. adults would now qualify as having the disease of obesity. Dave notes this validates many people who “feel” metabolically unwell despite a “normal” BMI. Reinforces his claim that “most people should be talking to their doctors about GLP-1s.” New Oral Triple Agonist (Ascletis – ASC41/ASC? Molecule) From Ascletis (A-S-C-L-E-T-I-S), developing an oral triple agonist targeting: GLP-1 GIP Glucagon Similar in mechanism to retatrutide, expected around 2027. Preclinical (animal) data show stunning results: Oral bioavailability of 4.2% 9× higher than tirzepatide 30× higher than oral semaglutide 6× higher than oral retatrutide 57× greater drug exposure than oral retatrutide Half-life ~56 hours Stronger receptor activation than retatrutide in vitro Suggests potential for the first powerful oral triple agonist—worth watching. ️ 3. Discussion of the Gray Market / TikTok Experience Dave briefly recounts losing his TikTok account and landing in an algorithm filled with teenagers promoting gray-market “retatrutide.” Expresses concern over unregulated peptide sales, especially to minors. Fractal Health's New Data – Weight Maintenance After Stopping GLP-1s New results from the Reveal One study (Fractal Health). Participants: lost 24% of body weight on GLP-1s → stopped injections → got one Revita procedure. At 6 months post-GLP-1 discontinuation: Weight changed only 1.5% (vs. ~10% regain in typical off-drug trials) HbA1c barely shifted Safety profile clean Suggests possible long-term weight maintenance without injections through gut mucosal re-lining. Dave describes his own recent attempt to switch drugs and significant hunger return. Food Noise & Biologic Hunger Dave discusses how stopping Mounjaro caused terrifying, primal hunger. Describes the distinction between: Food noise (brain-based thoughts) Hunger signals (biological/animalistic) Reinforces why many patients cannot maintain weight loss without support. Zepbound (Tirzepatide) Cash-Pay Price Reductions Eli Lilly drops cash-pay vial pricing: 2.5 mg: $349 → $299 5 mg: $499 → $399 7.5–15 mg: $499 → $449 Community feedback (informal poll): Most say still too high to leave compounded versions. Many would switch to branded if price hit $200–$300. Dave notes the Most Favored Nations agreement will push GLP-1 prices toward $250/month within 24 months. Alzheimer's Study (Novo Nordisk – EVOKE & EVOKE+) Oral semaglutide (Rybelsus, 14 mg) did not slow Alzheimer's clinical progression. Biomarkers improved but daily function and cognitive decline did not improve vs placebo. Important context: Oral Rybelsus is a weak form of semaglutide; stronger versions (like Wegovy 2.4 mg or upcoming high-dose oral Wegovy) not tested. Weight loss is not desirable in Alzheimer's patients, influencing drug selection. Dave emphasizes: This was a nearly $700M trial and an act of scientific courage. This is NOT the end of GLP-1 Alzheimer's research. Future molecules may target neurological pathways without suppressing appetite. Mentions Lilly's brenipatide, a GIP receptor agonist being developed for: Addiction Opioid dependency Possibly asthma ️ 8. Access, Cost, and Patient Empowerment Highlights Shed as a partner offering telehealth GLP-1 access. Notes many patients hide GLP-1 use from their primary care doctors. Reinforces OTP's mission: better, more honest conversations with clinicians. Shapa (Numberless Scale) & Dave's Personal Update Dave explains how the Shapa numberless scale helped him stay engaged during weight fluctuations. Finds stepping on “zones” (green/gray/blue) less emotionally damaging than numbers. Closing Notes Promises upcoming Eli Lilly savings card update. Encourages subscribing, liking, and enabling notifications for algorithm visibility. Thanks OTP community for amplifying patient-centric obesity medicine news. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

In this episode, Ben Azadi breaks down five science-backed metabolic drinks that naturally reduce arterial plaque, boost nitric oxide, lower inflammation, and support metabolic health — without medications or side effects. You'll learn: • Why arterial inflammation — not cholesterol — is the real silent killer• How pomegranate juice reversed arterial plaque by 30% in human studies• The surprising cardiovascular benefits of high-quality coffee with butter, olive oil, and salt• Why raw cacao improves arterial flexibility by up to 400% (Harvard study)• How apple cider vinegar and cinnamon lower fasting glucose, HbA1c, and triglycerides• The anti-inflammatory power of turmeric + black pepper and how it calms the arteries Ben also explains:• Which drink is best for diabetics• How to rotate the drinks weekly for maximum benefit• What markers to test before and after 30 days to measure progress (ApoB, CRP, fasting insulin, triglycerides, HDL, CAC score, and more) Plus, he shares a free guide revealing the five vegetables silently inflaming your gut and slowing your metabolism — and what to eat instead. A simple daily cup could dramatically upgrade your cardiovascular and metabolic health. FREE GUIDE: 5 Vegetables You Must Avoid To Lose Weight & Belly Fat - https://bit.ly/48CIprn

Episode 207: Understanding Hypertension and Diabetes (Pidjin English)Written by Michael Ozoemena, MD.You are listening to Rio Bravo qWeek Podcast, your weekly dose of knowledge brought to you by the Rio Bravo Family Medicine Residency Program from Bakersfield, California, a UCLA-affiliated program sponsored by Clinica Sierra Vista, Let Us Be Your Healthcare Home. This podcast was created for educational purposes only. Visit your primary care provider for additional medical advice.HypertensionSegment 1: What Is Hypertension?HOST:Let's start with the basics. Blood pressure is the force of blood pushing against the walls of your arteries. Think of it like water running through a garden hose—if the pressure stays too high for too long, that hose starts to wear out.Hypertension, or high blood pressure, means this pressure is consistently elevated. It is measured using two numbers:Systolic: the pressure when the heart beatsDiastolic: the pressure when the heart relaxesNormally reading is around 120/80 mmHg. Hypertension is defined by the American College of Cardiology/American Heart Association (ACC/AHA) as 130/80 mmHg or higher.The American Academy of Family Physicians (AAFP) defines hypertension as persistent elevation of systolic and/or diastolic blood pressure, with the diagnostic threshold for office-based measurement set at 140/90 mm Hg or higher.Segment 2: Why Should We Care?HOST:Hypertension is known as “the silent killer” because most people have no symptoms. Even without symptoms, it steadily increases the risk of:Heart attackStrokeKidney diseaseThink of high blood pressure as a constant stress test on your blood vessels. The longer it goes uncontrolled, the higher the chance of complications.Segment 3: What Causes High Blood Pressure?HOST:Hypertension usually doesn't have a single cause. It often results from a combination of genetic factors, lifestyle, and underlying medical conditions.Modifiable FactorsHigh-salt diet and low potassium intakePhysical inactivityTobacco useExcessive alcohol intakeOverweight or obesityChronic stressPoor sleep or sleep apneaNon-Modifiable FactorsFamily history of hypertensionBlack race (higher prevalence and severity)Age over 65Hypertension may also be secondary to other conditions, such as kidney disease, thyroid disorders, adrenal conditions, or medications like NSAIDs or steroids.Segment 4: How Is It Diagnosed?HOST:Diagnosis requires multiple elevated blood pressure readings taken on different occasions. This includes office readings, home blood pressure monitoring, or ambulatory blood pressure monitoring.If you haven't had your blood pressure checked recently, this is your reminder. It's simple—and it could save your life.Segment 5: Treatment and ManagementHOST:Lifestyle changes are often the first line of treatment:Reduce salt intakeEat more fruits, vegetables, and whole grainsAim for 150 minutes of moderate exercise per weekManage stressMaintain a healthy weightGet enough sleepLimit alcoholQuit smokingIf these steps aren't enough, medications may be necessary. These include:Diuretics, ACE inhibitors, ARBs, Calcium channel blockers, Beta-blockersYour healthcare provider will choose the best medication based on your health profile.Segment 6: What You Can Do TodayHOST:Here are three simple, actionable steps you can take right now:Check your blood pressure—at a clinic, pharmacy, or at home.Pay attention to your salt intake—much of it is hidden in processed foods.Move more—even a 20-minute daily walk can help reduce blood pressure over time.Small steps can lead to big, lasting improvements.SummaryHypertension may be silent but understanding it gives you power. Early action can add healthy years to your life. Take charge of your blood pressure today.Diabetes1. Wetin Diabetes Be and Wetin E Go Do to Person Body?Q: Wetin diabetes mean?A: Diabetes na sickness wey make sugar (glucose) for person blood too high. E happen because the body no fit produce insulin well, or the insulin wey e get no dey work as e suppose.Q: Wetin go happen if diabetes no dey treated well?A: If diabetes no dey treated well, e fit damage the blood vessels, nerves, kidneys, eyes, and even the heart.2. Wetin Cause Diabetes and Why Black People Suffer Pass?Q: Wetin cause diabetes?A: E no be one thing wey cause diabetes. E dey happen because of mix of gene, lifestyle, environment, and society factors.Q: Why Black/African Americans get diabetes more?A: Black people for America get diabetes more because of long-standing inequality, stress, low access to healthcare, and the kind environment wey many of them dey live in. These things dey make Black people more at risk.3. Diabetes Rates for America and Black People?Q: How many people get diabetes for America?A: For America today, over 38 million people get diabetes, and the number dey rise every year.Q: Why Black people dey suffer diabetes more than White people?A: About 12% of Black adults get diabetes, compared to just 7% for White adults. Black people also dey get the sickness earlier and e dey more severe.4. Signs and Symptoms of Diabetes?Q: Wetin be the early signs of diabetes?A: The early signs no too strong, but when e show, e fit include:Too much urine (polyuria)Thirst (polydipsia)Hunger, tiredness, and blurred visionWounds no dey heal fastTingling for hand or legSometimes weight loss5. How Doctor Go Diagnose Diabetes?Q: How doctor fit confirm say person get diabetes?A: Doctor go do some lab tests to confirm:Fasting Plasma Glucose (FPG): 126 mg/dL (7.0 mmol/L) or higherHbA1c: 6.5% or higher2-hour Oral Glucose Tolerance Test (OGTT): 200 mg/dL (11.1 mmol/L) or higher after person drink glucose.Random Blood Glucose: 200 mg/dL (11.1 mmol/L) or higher plus classic symptoms like too much urination, thirst, or weight loss.Q: Wetin happen if HbA1c test no match the person?A: If HbA1c result no match person symptoms, doctor fit repeat test or try other tests like FPG or OGTT.6. Wetin Screening and Early Diagnosis Fit Do?Q: Why screening for diabetes dey important?A: Screening dey important because early detection fit prevent serious complications from diabetes.Q: How often person go do diabetes test?A: Adults wey get overweight or obesity, between 35–70 years, suppose do diabetes screening every three years. But because Black adults get higher risk, doctors dey start screening earlier and more often.7. How Person Fit Manage Diabetes?Q: Wetin be the best way to manage diabetes?A: The two main ways to manage diabetes be:Lifestyle changes: Eat better food (vegetables, fruits, whole grain, beans, fish, chicken) and exercise regularly.Medicine: If person sugar still high, doctor fit give drugs like metformin, SGLT-2 inhibitors, or GLP-1 receptor agonists.Q: Wetin be SGLT-2 inhibitors and GLP-1 drugs?A: SGLT-2 inhibitors dey help with kidney and heart problems, while GLP-1 drugs dey help with weight loss and prevent stroke.Q: Wetin be first-line treatment for diabetes?A: First-line treatment for diabetes be metformin, unless person no fit tolerate am.Q: How much exercise a person suppose do?A: Person suppose do at least 150 minutes of moderate exercise per week. This fit include things like brisk walking, swimming, or cycling. E also good to add muscle-strength training two or three times weekly to help control sugar.Q: When insulin therapy go be needed?A: Insulin therapy go be needed if person A1c is higher than 10%, or if person dey hospitalized and their glucose dey above the 140-180 range. This go help bring the blood sugar down quickly.8. Wetin Be the Complications of Diabetes?Q: Wetin fit happen if diabetes no dey well-managed?A: Complications fit include kidney disease, blindness, nerve damage, leg ulcers, heart attack, stroke, and emotional issues like depression.Q: Why Black adults get more complications?A: Black people get higher risk of these complications because of inequality, stress, and poor access to healthcare.9. Wetin Dey Affect Access to Diabetes Treatment?Q: Wetin make Black people struggle to get treatment for diabetes?A: Many Black people no dey get new effective treatments like GLP-1 and SGLT-2 inhibitors because of price, insurance issues, and lack of access. COVID-19 also worsen things.Q: Wetin government and doctors fit do?A: Policymakers dey work on improving access to drugs, better community programs, and screening for social issues wey fit affect diabetes care.10. ConclusionQ: Wetin be the solution to reduce diabetes impact?A: The solution go need medical treatment, early screening, lifestyle support, and policy changes. With proper treatment and community support, e possible to reduce the impact of diabetes, especially for Black communities.Even without trying, every night you go to bed a little wiser. Thanks for listening to Rio Bravo qWeek Podcast. We want to hear from you, send us an email at RioBravoqWeek@clinicasierravista.org, or visit our website riobravofmrp.org/qweek. See you next week! _____________________References: Whelton PK, Carey RM. Overview of hypertension in adults. UpToDate. 2024.Carey RM, Moran AE. Evaluation of hypertension. UpToDate. 2024.Mann SJ, Forman JP. Lifestyle modification in the management of hypertension. UpToDate. 2024.Giles TD, Weber MA. Initial pharmacologic therapy of hypertension. UpToDate. 2024.American Heart Association. Understanding Blood Pressure Readings. Accessed 2025.American Heart Association. AHA Dietary and Lifestyle Recommendations. Accessed 2025.Theme song, Works All The Time by Dominik Schwarzer, YouTube ID: CUBDNERZU8HXUHBS, purchased from https://www.premiumbeat.com/.

This week on Fat Science, Dr. Emily Cooper, Mark Wright, and Andrea Taylor field your most urgent metabolic health questions—exploring care advocacy, novel drug use, lab results, and how to filter fact from fiction in the TikTok age. Dr. Cooper offers clinical clarity, real-world perspective, and actionable hope—with an emphasis on what truly matters for your long-term health and energy.Hear from listeners experiencing real breakthroughs (and challenges) with GLP-1s, get tips for navigating confusing cholesterol results, and learn why self-advocacy and good science matter more than credentials or hype. This is not a quick-fix episode; it's real metabolic medicine, mythbusting, and grounded encouragement for your health journey.Key Questions AnsweredWhat labs and scores best assess your true metabolic risk—and how do you make sense of fasting glucose, glucose-insulin ratio (GIR), and FIB-4?How can you find a medical provider who'll actually give you the time and attention metabolic care requires?Why do GLP-1s benefit more than weight loss alone? Listeners report help with sleep apnea, inflammation, and food noise—what does the science say?How should you reintroduce carbs after restriction, and what's the safest way to monitor (beyond A1C)?What's up with rising cholesterol on Zepbound, and when do you worry?Does serotonin syndrome relate to GLP-1s? (Short answer: No—Dr. Cooper explains why.)What are the dangers of “GLP-1 microdosing” as pushed by social media, and what happens when influencers overstep good science?Key TakeawaysCare that cares: The best doctor isn't always the most credentialed—find someone, MD, NP, or PA, who takes your questions seriously and goes deeper than the surface. Labs that matter: Fasting glucose, insulin, GIR, HbA1c, plus advanced lipid testing (CardioIQ, NMR) are critical for uncovering hidden risk—not just chasing numbers. GLP-1s act broadly: Listeners see gains in sleep, inflammation, and appetite regulation. These benefits are real, not just anecdotal, and Dr. Cooper shares the clinical rationale. Smart fueling, even on GLP-1s: If you lack hunger cues, “mechanical eating” prevents under-fueling and cellular stress—especially important for maintaining muscle and metabolism. Rethinking “microdosing”: TikTok trends are not medical advice—microdosing with black-market GLP-1s is unproven, poorly regulated, and potentially unsafe. Rely on trusted, legal medication sources only. Dr. Cooper's Actionable TipsRequest a full panel for metabolic health: ask your provider about fasting insulin, GIR, HbA1c, lipids, and FIB-4—even if you haven't been flagged as “at risk”. For those on GLP-1s: Don't skip meals; create a schedule with protein and fiber to avoid muscle loss and ensure micronutrient intake. Experiencing cholesterol shifts on medication? Ask for a breakdown (HDL, LDL, particle size) and consider advanced panels (CardioIQ, NMR) to better understand your risk. If reintroducing carbs after restriction, pair them with protein or fat and test glucose/insulin at intervals post-meal to personalize your plan. Avoid unregulated “microdosing” and buy only from reputable, FDA-approved outlets—protect your long-term health over quick fixes. Notable Quote“The most important thing is somebody who cares, not necessarily their degrees.”— Dr. Emily CooperLinks & ResourcesPodcast Home: Fat Science Podcast WebsiteSubmit a Show Question: questions@fatsciencepodcast.com or dr.c@fatsciencepodcast.comDr. Emily Cooper on LinkedInMark Wright on LinkedInAndrea Taylor on InstagramAdvanced cholesterol testing: CardioIQ at Quest, NMR at LabCorpFat Science is your source for breaking diet myths and advancing the science of true metabolic health. No diets, no agendas—just science that makes you feel better. The show is informational only and does not constitute medical advice. 

Why You Should Listen:  In this episode, you will learn about the vast role that nitric oxide plays in supporting health and strategies to increase nitric oxide. About My Guest: My guest for this episode is Beth Shirley.  Beth Shirley, RPh, CCN, developed an expertise as a compounding pharmacist and board-certified clinical nutritionist during a career spanning over 40 years.  She has been a pioneer at the cutting edge of the evolution of what has now come to be known as "Integrative Pharmacy", the junction between traditional pharmacy and the clinical use of nutritional supplementation.  Since 2009, Beth has spent time working with some of the leading thought leaders in the world of nitric oxide research and through this has developed an in-depth knowledge of the topic and its potential applications in patient care.  In addition, she has worked closely with the scientific community and cutting-edge companies working on innovative nutritional ingredients and approaches for their use in a variety of life's challenges. In fact, Beth has formulated a product that was awarded the first patent on a supplement to "increase sexual desire and pleasure".  She currently is the Director of Education and Research for Approved Medical Solutions, the distributor of her oxalate-free nitrate product and her Libby line of women's wellness products. Key Takeaways: What is nitric oxide (NO)? What functions does NO play in the body? What causes NO to be low? How can NO be supported with diet? Does NO level play a role in COVID? What is the connection between NO and methylation? Does NO have a role in the management of infections? What are the two pathways through which NO is created in the body? What is the connection between glyphosate and NO? How can any potential downsides of increasing NO be minimized? What is the role of NO in systemic inflammation? How does NO impact glucose, insulin, HbA1c, metabolic syndrome, and diabetes? What role does NO play in cardiovascular disease? Does NO impact MCAS and histamine? Can NO have a beneficial effect on intestinal hyperpermeability or on the microbiome? Does NO impact detoxification? Can methylene blue be used with NO? Connect With My Guest:  LinkedIn Related Resources: To view details about the products discussed in this episode, visit Approved Medical Solutions. Nitric Oxide (N-O) Libby Line To purchase products discussed in this episode, you must first create an account.  Use Referral Code BETTERHEALTH to create your account. Once registered, you will receive 10% off on all orders and an additional 5% off on your first order using discount code BETTERHEALTH. Interview Date: October 30, 2025 Transcript: To review a transcript of this show, visit https://BetterHealthGuy.com/Episode224. Support the Show: To support the show and Buy Me a Coffee, visit https://betterhealthguy.link/BuyMeACoffee. Additional Information: To learn more, visit https://BetterHealthGuy.com. Follow Me on Social Media: Facebook - https://facebook.com/betterhealthguy Instagram - https://instagram.com/betterhealthguy X - https://twitter.com/betterhealthguy TikTok - https://tiktok.com/@betterhealthguy Disclosure: BetterHealthGuy.com is an affiliate of Approved Medical Solutions. Disclaimer:  The content of this show is for informational purposes only and is not intended to diagnose, treat, or cure any illness or medical condition. Nothing in today's discussion is meant to serve as medical advice or as information to facilitate self-treatment. As always, please discuss any potential health-related decisions with your own personal medical authority. 

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If you want to improve your energy and long-term health, start by understanding how your body uses glucose.In this episode of A Whole New Level, Dr. Benjamin Bikman, scientist and author of Why We Get Sick, joins Mike Haney to unpack the science of glucose metabolism and insulin resistance—and why blood sugar isn't the whole story.Dr. Bikman explains how insulin regulates energy balance, why HbA1c is only part of the picture, and how chronic high insulin can silently drive weight gain, fatigue, and metabolic disease. He also shares practical ways to lower insulin naturally through diet, exercise, and daily habits.They discuss:Why insulin, not glucose, is the root of metabolic dysfunctionWhat HbA1c and fasting glucose really tell youThe early signs of insulin resistance most people missHow muscle tissue protects against high glucose and insulinWhy low-carb and intermittent fasting aren't one-size-fits-allPractical nutrition and movement strategies for better metabolic flexibilitySign Up to Get Your Free Ultimate Guide to Glucose: https://levels.link/wnl

n the News.. COVID-19 & T1D, Ozempic Pill Progress, Faster Insulin, “Beyond Misconceptions,” and More It's In the News.. a look at the top headlines and stories in the diabetes community. This week's top stories: A new study looks at the link between COVID-19 and very young children, Lilly moves ahead with their Ozempic oral pill, ultra-rapid insulin clears another hurdle, Beyond Type 1 launches a new campaign and more! Find out more about Moms' Night Out  Please visit our Sponsors & Partners - they help make the show possible! Learn more about Gvoke Glucagon Gvoke HypoPen® (glucagon injection): Glucagon Injection For Very Low Blood Sugar (gvokeglucagon.com) Omnipod - Simplify Life Learn about Dexcom   Check out VIVI Cap to protect your insulin from extreme temperatures The best way to keep up with Stacey and the show is by signing up for our weekly newsletter: Sign up for our newsletter here Here's where to find us: Facebook (Group) Facebook (Page) Instagram Twitter Check out Stacey's books! Learn more about everything at our home page www.diabetes-connections.com  Reach out with questions or comments: info@diabetes-connections.com Episode transcription with links: Hello and welcome to Diabetes Connections In the News! I'm Stacey Simms and every other Friday I bring you a short episode with the top diabetes stories and headlines happening now. XX https://www.scientificamerican.com/article/advances-in-type-1-diabetes-science-and-tech/ This article is part of “Innovations In: Type 1 Diabetes,” an editorially independent special report that was produced with financial support from Vertex. XX More evidence linking COVID 19 to type 1 diabetes.. but still exactly why is a mystery. During the COVID-19 pandemic, there was an unexpected increase in the number of cases of type 1 diabetes in Sweden, particularly among children under 5 and young adult men. The infection accelerated the onset of diabetes among children between the ages of 5 and 9. The researchers looked at data from a 17-year period on the incidence of type 1 diabetes among all people under the age of 30 in Sweden. In addition, they compared the risk of developing diabetes among 720,000 individuals with positive COVID-19 tests against a control group of 3.5 million people. The findings are published in the journal Diabetologia. The number of diabetes cases increased by 12% in 2021 and 9% in 2022 compared with previous years. In 2023, the number of cases was back to a normal level. Despite this, the researchers cannot distinguish a clear connection between COVID-19 infection and diabetes, except for children between 5 and 9 years old. They had an increased risk of type 1 diabetes about one month after a COVID-19 infection even though their total risk did not increase. "However, it's clear that the COVID-19 vaccine can be ruled out as a cause of the increase in diabetes cases. The recommendation for the age group where we saw the strongest increase was not to get vaccinated. In addition, other studies on adults have shown that vaccination reduces the risk of developing type 1 diabetes after a COVID infection." https://medicalxpress.com/news/2025-10-diabetes-young-people-pandemic.html XX A new gene therapy approach aimed at protecting people with type 1 diabetes from developing diabetic kidney disease—a serious and common complication of the condition, has shown promising results in a University of Bristol study. Findings from this new study, published in Molecular Therapy, demonstrated a 64% reduction in a damage indicator for kidney disease, paving the way for a potential new treatment. The study, explored the potential of delivering a protein called VEGF-C directly into kidney cells. Previous studies have shown VEGFC could protect against kidney disease as it helps keep blood vessels in the kidney filter healthy, repairing early signs of diabetes-related kidney damage. https://medicalxpress.com/news/2025-10-gene-therapy-kidney-disease-diabetes.html XX The FDA has agreed to consider Afrezza inhaled insulin for children and teens. The company said in August that it submitted a supplemental Biologics License Application (sBLA) for Afrezza in the pediatric population and it's been assigned a decision deadline date of the end of May, 2026. Afrezza first recieved FDA approval for adults (age 18 and up) in June 2014 https://www.drugdeliverybusiness.com/fda-accepts-application-mannkind-inhaled-insulin-kids/ Update on inhaled insulin for kids.. in the open-label, randomized, phase 3 INHALE-1 clinical trial Afrezza demonstrated safe and effective replacement for rapid-acting meal insulin in children with type 1 diabetes (T1D and demonstrates comparable glycemic control to injected rapid-acting insulin. The INHALE-1 clinical trial assessed the safety and efficacy of Afrezza among children and adolescents with T1D, including a total of 230 patients aged 4 to 17 years. Researchers used basal injected insulin and randomly assigned inhaled insulin or rapid-acting analogue for meals, evaluating the change in hemoglobin A1c levels at 26 weeks. After completing 26 weeks of randomly assigned treatment with either Afrezza or rapid-acting insulin injections combined with basal insulin, participants continued receiving the inhaled insulin until week 52 for an extension phase to evaluate the safety and effectiveness of Afrezza with continued use.1,2 https://www.pharmacytimes.com/view/inhaled-insulin-demonstrates-comparable-safety-lung-function-and-efficacy-to-injectable-insulin-in-type-1-diabetes XX Eli Lilly released the results of two new Phase 3 trials of an experimental GLP-1 pill that the company says could become a “foundational treatment” for type 2 diabetes. The Indianapolis-based drugmaker plans to submit global regulatory applications for orforglipron in the treatment of type 2 diabetes next year. The company said it will seek approval of the drug as an obesity medication by the end of 2025. Lilly is trying to build on the success of its Mounjaro/Zepbound franchise by offering patients a pill instead of an injection. But the company is trailing behind rival Novo Nordisk in developing an oral alternative, and data released so far has raised some skepticism among investors. A study released in August showed that orforglipron could help patients lose an average of about 12% of their body weight. Wall Street had been expecting more; Lilly's injectable drug Zepbound produced weight loss of as much as 21%, and Novo Nordisk has achieved 15% weight loss percentages for both oral and injectable versions of its Wegovy medication.   https://www.fiercebiotech.com/biotech/eli-lillys-orforglipron-bests-farxiga-padding-oral-glp-1-case-pair-phase-3-diabetes-wins   XX XX UF Health Cancer Center researchers have found a surprising culprit behind common health problems such as obesity, diabetes and fatty liver disease: silent genetic glitches in the blood system that occur naturally as people age. The findings, published in the Journal of Clinical Investigation, mean that in the future, simple blood tests could be developed to identify people most at risk early on, helping prevent chronic illnesses and cancer through strategies like diet or lifestyle changes. As people age, stem cells in the bone marrow that produce blood cells gradually accumulate mutations in their DNA. Most mutations don't cause any issues, but sometimes blood stem cells with a mutation can start crowding out their peers. Called clonal hematopoiesis, this condition affects about 10% of older people and is associated with an increased risk of blood cancers like leukemia. It's also linked to a higher risk of obesity and diabetes. But the prevailing thinking was that obesity and related conditions promoted blood cell changes, not the other way around. The new study reverses that. The implications could be far-reaching, particularly as obesity has now overtaken smoking as the most significant and preventable risk factor for cancer. The team is studying how the mutations drive disease. Next, they plan to test how drugs like those commonly used to treat diabetes and new popular weight loss drugs might help reverse or prevent diseases caused by blood cell changes. https://medicalxpress.com/news/2025-10-hidden-blood-mutations-obesity-diabetes.html XX A new ultra rapid insulin continues to move forward. A phase 3 clinical trial of BioChaperone Lispro (liss-pro) conducted in China found it safe and effective compared with Humalog along with a significant reduction of the rise of blood glucose after a test meal.     These results complete and confirm the positive outcomes previously obtained with THDB0206 injection in people with Type 2 Diabetes It combines Adocia's proprietary BioChaperone® technology with insulin lispro, the active ingredient in the standard of care, Humalog® (Eli Lilly).   This innovative formulation acts significantly faster https://pharmatimes.com/news/ultra-rapid-insulin-shows-promise-in-phase-3-trial-for-type-1-diabetes/   Poor blood sugar control in adolescent patients with type 1 diabetes (T1D) may be associated with a higher risk of neuropathy in adulthood, according to recent research from the University of Michigan.1 The study included children diagnosed with T1D between 1990-1992 who were recruited into the Cognition and Longitudinal Assessment of Risk Factors over 30 Years cohort study in Australia. Investigators collected HbA1c from medical records, and microvascular complications were assessed through self-reports, clinical screenings, retinal photographs, and urinary albumin-creatinine testing.3   A total of 30 children were recruited from the original cohort with a mean diagnosis age of 2.9 years. After an average of 29.7 years (standard deviation [SD]: 3.9 years), 33% of participants (n = 13) developed neuropathy, 63% (n = 19) developed diabetes-related eye disease, and 10% (n = 3) developed neuropathy.3 Mean HbA1c estimates during adolescence (9% [74.9 mmol/mol]; 95% CI, 8.6-9.3 [70.5-78.1]) were substantially higher than childhood (8.2% [66.1 mmol/mol]; 95% CI, 7.8-8.5 [61.7-69.4]; P

It's In the News.. a look at the top headlines and stories in the diabetes community. This week's top stories: Sanofi lowers prices, oral pill for T1D prevention studied, updates from Medtronic, Tandem, and Sequel Med Tech, falsely lower A1Cs (and why that happens), Biolinq gets FDA okay for micro-needle CGM and more! Find out more about Moms' Night Out  Please visit our Sponsors & Partners - they help make the show possible! Learn more about Gvoke Glucagon Gvoke HypoPen® (glucagon injection): Glucagon Injection For Very Low Blood Sugar (gvokeglucagon.com) Omnipod - Simplify Life Learn about Dexcom   Check out VIVI Cap to protect your insulin from extreme temperatures The best way to keep up with Stacey and the show is by signing up for our weekly newsletter: Sign up for our newsletter here Here's where to find us: Facebook (Group) Facebook (Page) Instagram Twitter Check out Stacey's books! Learn more about everything at our home page www.diabetes-connections.com  Reach out with questions or comments: info@diabetes-connections.com Episode transcription with links:   Hello and welcome to Diabetes Connections In the News! I'm Stacey Simms and every other Friday I bring you a short episode with the top diabetes stories and headlines happening now. XX French drugmaker Sanofi says it would offer a month's supply of any of its insulin products for $35 to all patients in the U.S. with a valid prescription, regardless of insurance status. The program, originally meant for uninsured diabetes patients, would now include those with commercial insurance or Medicare, the drugmaker said. Patients will be able to purchase any combination, type, and quantity of Sanofi insulins with a valid prescription for the fixed monthly price of $35, starting January 1. Lilly and Novo also have similar programs through which they offer insulin products for $35 a month for U.S. patients regardless of whether the patients have insurance. There is no law at work here – the only legislation that has changed the price of insulin came with the Inflation Reduction Act in 2022 with the Medicare cap. Helping lower the cost here, biosimilars hitting the market and the huge profitability for GLP-1 drugs for Novo and Lilly https://www.reuters.com/business/healthcare-pharmaceuticals/sanofi-offer-all-insulin-products-35-per-month-us-2025-09-26/ XX A pill typically prescribed for rheumatoid arthritis and alopecia might help slow the progression of type 1 diabetes, a new study says. Baricitinib (bare-uh-SIT-nib) safely preserved the body's own insulin production in people newly diagnosed with type 1 diabetes.. and their diabetes started progressing once they stopped taking baricitinib, results show. They produced less insulin and had less stable blood sugar levels.   Baricitinib works by quelling signals in the body that spur on the immune system, and is already approved for treating autoimmune conditions such as rheumatoid arthritis, ulcerative colitis and alopecia, researchers said.   “Among the promising agents shown to preserve beta cell function in type 1 diabetes, baricitinib stands out because it can be taken orally, is well tolerated, including by young children, and is clearly efficacious,” Waibel said. “We are hopeful that larger phase III trials with baricitinib are going to commence soon, in people with recently diagnosed type 1 diabetes as well as in earlier stages to delay insulin dependence,” she added. “If these trials are successful, the drug could be approved for type 1 diabetes treatment within five years.”   Findings presented at medical meetings should be considered preliminary until published in a peer-reviewed journal.   https://www.usnews.com/news/health-news/articles/2025-09-23/pill-effective-in-slowing-type-1-diabetes-progression XX An existing transplant drug has shown promise in slowing the progression of type 1 diabetes in newly diagnosed young people, potentially paving the way for the first therapy that modifies the disease after diagnosis. The Drug, called ATG, is currently used together with other medicines to prevent and treat the body from rejecting a kidney transplant. It can also be used to treat rejection following transplantation of other organs, such as hearts, gastrointestinal organs, or lungs. The researchers studied 117 people aged five to 25, who'd been diagnosed with type 1 diabetes within the past three to nine weeks. The participants were from 14 centers across eight European countries and were randomized to be given different doses of ATG (0.1, 0.5, 1.5, or 2.5 mg/kg) or a placebo. ATG was given as a two-day intravenous (IV) infusion. The main goal was to see how well the pancreas could still make insulin after 12 months, measured by C-peptide levels during a special meal test. C-peptide is released into the blood along with insulin by the pancreas.   The findings are promising, showing that ATG, even at a relatively low dose, can slow the loss of insulin-producing cells in young people newly diagnosed with type 1 diabetes. The lower dose also caused fewer side effects, making it a more practical option. https://newatlas.com/disease/antithymocyte-globulin-newly-diagnosed-type-1-diabetes/     XX The FDA has delayed its feedback on Lexicon Pharmaceuticals' application to bring Zynquista (sotagliflozin) to people with type 1 diabetes. The agency had planned to respond this month but will now wait until the fourth quarter after reviewing new data from ongoing studies. Zynquista, an oral drug meant to be used with insulin, has already been approved for heart failure (marketed as Inpefa). But in type 1 diabetes, it faces safety concerns: last year an FDA advisory committee voted 11–3 that its benefits don't outweigh the increased risk of diabetic ketoacidosis (DKA). The FDA later issued a complete response letter rejecting the drug. Lexicon is still pushing forward, hoping its additional submissions will strengthen Zynquista's case for type 1 diabetes approval. https://www.biospace.com/fda/after-fda-rejection-lexicons-type-1-diabetes-drug-hit-with-another-regulatory-delay     XX A common but often undiagnosed genetic condition may be causing delays in type 2 diabetes diagnoses and increasing the risk of serious complications for thousands of Black and South Asian men in the UK—and potentially millions worldwide. A new study found around one in seven Black and one in 63 South Asian men in the UK carry a genetic variant known as G6PD deficiency. Men with G6PD deficiency are, on average, diagnosed with type 2 diabetes four years later than those without the gene variant. But despite this, fewer than one in 50 have been diagnosed with the condition.   G6PD deficiency does not cause diabetes, but it makes the widely used HbA1c blood test—which diagnoses and monitors diabetes—appear artificially low. This can mislead doctors and patients, resulting in delayed diabetes diagnosis and treatment.   The study found men with G6PD deficiency are at a 37% higher risk of developing diabetes-related microvascular complications, such as eye, kidney, and nerve damage, compared to other men with diabetes.   "This study highlights important evidence that must be used to tackle these health inequalities and improve outcomes for Black communities. Preventative measures are now needed to ensure that Black people, especially men, are not underdiagnosed or diagnosed too late." https://medicalxpress.com/news/2025-09-hidden-genetic-delay-diabetes-diagnosis.html XX Novo Nordisk today announced the resubmission of its Biologics License Application (BLA) to the US Food and Drug Administration (FDA) for Awiqli® (insulin icodec) injection, a once-weekly basal insulin treatment for adults living with type 2 diabetes. If approved, Awiqli® would become the first once-weekly basal insulin available in the United States, providing an alternative to daily basal insulin injections for adults living with type 2 diabetes.   The resubmission is based on results from the ONWARDS type 2 diabetes phase 3a program for once-weekly Awiqli® which is comprised of five randomized, active-controlled, treat-to-target clinical trials in approximately 4,000 adults with type 2 diabetes. The clinical program evaluated Awiqli® vs. daily basal insulin and the primary endpoint in these trials was change in A1C from baseline.1-5 Awiqli® is approved in the EU, along with 12 additional countries. In addition, regulatory filings have been completed in several other countries, with further regulatory decisions expected in 2025. XX Interesting news from Sequel Med Tech – they've signed an agreement with Arecor to pair the twiist pump with AT278 an ultra-concentrated (500U/mL), ultra-rapid insulin in development. They also have a deal with Medtronic to develop insulin for new pumps. This insulin isn't yet approved, it's 5 times stronger than standard fast acting  it's hoped that a clinical study will begin next year. Arecor says its insulin could potentially be the only option capable of enabling and catalyzing the next generation of longer-wear and miniaturized automated insulin delivery systems.   https://www.drugdeliverybusiness.com/sequel-arecor-develop-rapid-insulin-twiist/ XX Tandem Diabetes Care announes its t:slim X2™ insulin pump with Control-IQ+ automated insulin delivery (AID) technology is now cleared for use with Eli Lilly and Company's Lyumjev® (insulin lispro-aabc injection) ultra-rapid acting insulin in the United States (U.S.).   – The t:slim X2 insulin pump with Control-IQ+ technology is now cleared for use with Lyumjev for people with type 1 diabetes ages 2 and above and all adults with type 2 diabetes. The companies are continuing to work toward securing Lyumjev compatibility for the Tandem Mobi pump. https://hitconsultant.net/2025/09/29/tandem-diabetes-cares-tslim-x2-pump-cleared-for-use-with-lillys-ultra-rapid-lyumjev-insulin/ XX You can now place your order for the MiniMed™ 780G system with the Instinct sensor, made by Abbott. And if you are already a MiniMed 780G user, you can place an upgrade order today. ​This is a 15 day wear sensor, with no transmitter or overtape required. It looks the same at other Abbot sensors such as the Libre but is proprietary to Medtronic. Shipments are scheduled to start in November.   ​ https://www.drugdeliverybusiness.com/medtronic-launches-minimed-780g-instinct-abbott/   XX The global type 1 diabetes (T1D) burden continues to increase rapidly driven by rising cases, ageing populations, improved diagnosis and falling death rates. ,   The study estimates that T1D will affect 9.5 million people globally in 2025 (up by 13% since 2021), and this number is predicted to rise to 14.7 million in 2040. However, due to lack of diagnosis and challenges in collecting sufficient data, the actual number of individuals living with T1D is likely much higher, researchers say.   In fact, they estimate that there are an additional 4.1 million 'missing people' who would have been alive in 2025 if they hadn't died prematurely from poor T1D care, including an estimated 669,000 who were not diagnosed. This is particularly true in India, where an estimated 159,000 people thought to have died from missed diagnoses. The study predicts that 513,000 new cases of T1D will be diagnosed worldwide in 2025, of which 43% (222,000) will be people younger than 20 years old. Finland is projected to have the highest incidence of T1D in children aged 0-14 years in 2025 at around 64 cases per 100,000. The substantial increases in T1D forecasts between 2025 and 2040 underscore the urgent need for action. As co-author Renza Scibilia from Breakthrough T1D explains, "Early diagnosis, access to insulin and diabetes supplies, and proper healthcare can bring enormous benefits, with the potential to save millions of lives in the coming decades by ensuring universal access to insulin and improving the rate of diagnosis in all countries."   The authors note some important limitations to their estimates, including that while the analysis uses the best available data, predictions are constrained by the lack of accurate data in most countries-highlighting the urgent need for increased surveillance and research. They also note that data on misdiagnosis and adult populations remain limited, and the analysis assumes constant age-specific incidence and mortality over time. Furthermore, incidence data from the COVID-19 period were excluded from part of the modelling to avoid bias. Future updates are expected to improve as new data become available and applied. https://www.news-medical.net/news/20250919/New-study-warns-of-millions-of-undiagnosed-and-missing-people-with-type-1-diabetes.aspx XX A new study has found that semaglutide — the active ingredient found in some GLP-1 medications prescribed for diabetes and to aid weight loss — may help protect the eyes from diabetic retinopathy. Researchers estimate that as much as 40% of all people with diabetes also have diabetic retinopathy — a potentially blinding eye condition caused by blood vessel damage in the eye's retina. There is currently no cure for diabetic retinopathy. The condition is often managed through injections of anti-VEGF medications into the eye, surgery, and blood sugar monitoring and control. For this lab-based study, researchers used samples of human retinal endothelial cells that were treated with different concentrations of semaglutide. The cells were then placed in a solution with both a high glucose level and high level of oxidative stress — where there is an imbalance of antioxidants and free radicals — for 24 hours.   Past studies show that oxidative stress plays a role in the formation of diabetic retinopathy.   At the study's conclusion, researchers found that the retinal cells treated with semaglutide were twice as likely to survive than cells that were untreated. Additionally, the treated cells were found to have larger stores of energy.   Scientists also found that three markers of diabetic retinopathy were decreased in the semaglutide-treated retinal cells. First, the levels of apoptosis — a form of cell death — decreased from about 50% in untreated cells to about 10% in semaglutide-treated cells. The production of the free radical mitochondrial superoxide decreased from about 90% to about 10% in the treated retinal cells.   Researchers also found the amount of advanced glycation end-products — harmful compounds that can collect in people with diabetes and are known to cause oxidative stress — also decreased substantially.   Lastly, scientists reported that the genes involved in the production of antioxidants were more active in the semaglutide-treated cells when compared to untreated cells. Researchers believe this is a sign that semaglutide may help repair damage to the retinal cells.   “Our study did not find that these drugs harmed the retinal cells in any way — instead, it suggests that GLP1-receptor agonists protect against diabetic retinopathy, particularly in the early stages,” Ioanna Anastasiou, PhD, molecular biologist and postdoctoral researcher at the National and Kapodistrian University in Greece, and lead author of this study, said in a press release.   “Excitingly, these drugs may be able to repair damage that has already been done and so improve sight. Clinical trials are now needed to confirm these protective effects in patients and explore whether GLP-1 receptor agonists can slow, or even halt, the progression of this vision-robbing condition.” https://www.medicalnewstoday.com/articles/ozempic-semaglutide-may-help-protect-against-diabetes-related-blindness-retinopathy   XX Biolinq has received De Novo Classification from the U.S. Food and Drug Administration for its lead product, Biolinq Shine, a patch on the forearm that provides real-time glucose feedback through a primary color-coded LED display, visible with or without a phone. This one is tricky – it's called a needle free CGM but it also says it uses micro needles. By the way, De Novo isn't exactly the same as what we think of for FDA approval for medical devices. It's not as rigorous but it's a streamlined route for novel, low to moderate risk devices with no existing equivalent. We'll see how this one turns out. https://www.hmenews.com/article/biolinq-s-multi-function-biosensor-receives-fda-de-novo-classification

Thank you for joining us for our 2nd Cabral HouseCall of the weekend! I'm looking forward to sharing with you some of our community's questions that have come in over the past few weeks…   Chrissy: Hi dr Cabral Is it ok to that estrogel and progesterone for menopause if you have lymphoedema ? Or will it make it worse .. kind regards Chrissy                                                                                                                                                    Kay: Hi Dr. Cabral- What are your thoughts on Metformin combined w Naltrexone topiramate and Vit B12 for Tx of PCOS? My 31 y.o. daughter has tried over the last few years to manage her PCOS w traditional Chinese herbs, acupuncture, yoga & pilates which have only given her limited success. Her HbA1c were in the pre-diabetic range. She lives in the NYC area w a demanding job. Now, working w a Functional Med provider, her tests showed high levels of cortisol throughout the day & hormonal imbalances. Weekend hikes & being near nature on occasion have helped her stress levels as shown by her Oura ring data. After about a month of the Rx regimen, she has noticed an improvement in her HbA1c and has hired a personal trainer. For true, sustainable wellness, what do you recommend?                                       Becky: Hi Dr. Cabral! Thank you for ALL that you do and thank you for using your story to help heal others! I am an IHP2 and need advice. I am working with a client, she is in her mid 30s and she has had horrific breath and overall dryness of her entire body since a child. Her dad and siblings have the same issues along with her oldest daughter. She has tried EVERY imaginable product to fix her breath with zero success. She has done the 21 day detox, & is finishing up the CBO Protocol with H.Pylori & will be starting the Finisher. She did a HTMA last year with someone else but nothing alarming. She is hopeless that her breath can't be fixed. What is your suggestion as to what direction we should go next? She does not drink filtered water, is on birth control & an anti depressant. THANKS!!!!            Kayley: I am 24 yrs old 5'2" 123lbs. I have diagnosed Rheumatoid Arthritis that has severely impacted my life. I currently take Methotrexate, Plaquenil, Folic Acid, and Folinic Acid. I am struggling with debilitating fatigue, and my IBS has recently flared up. Is there anything you would suggest doing to improve energy levels?                               Amanda: Does chiropractic treatment benefit children diagnosed with ADHD?     Thank you for tuning into this weekend's Cabral HouseCalls and be sure to check back tomorrow for our Mindset & Motivation Monday show to get your week started off right! - - - Show Notes and Resources: StephenCabral.com/3509 - - - Get a FREE Copy of Dr. Cabral's Book: The Rain Barrel Effect - - - Join the Community & Get Your Questions Answered: CabralSupportGroup.com - - - Dr. Cabral's Most Popular At-Home Lab Tests: > Complete Minerals & Metals Test (Test for mineral imbalances & heavy metal toxicity) - - - > Complete Candida, Metabolic & Vitamins Test (Test for 75 biomarkers including yeast & bacterial gut overgrowth, as well as vitamin levels) - - - > Complete Stress, Mood & Metabolism Test (Discover your complete thyroid, adrenal, hormone, vitamin D & insulin levels) - - - > Complete Food Sensitivity Test (Find out your hidden food sensitivities) - - - > Complete Omega-3 & Inflammation Test (Discover your levels of inflammation related to your omega-6 to omega-3 levels) - - - Get Your Question Answered On An Upcoming HouseCall: StephenCabral.com/askcabral - - - Would You Take 30 Seconds To Rate & Review The Cabral Concept? The best way to help me spread our mission of true natural health is to pass on the good word, and I read and appreciate every review!  

Thank you for joining us for our 2nd Cabral HouseCall of the weekend! I'm looking forward to sharing with you some of our community's questions that have come in over the past few weeks…   Suzanne: Thank you for your time in advance. In late 2021, my husband was diagnosed with Stage IV prostate cancer. He underwent six rounds of chemo along with Eligard injections. After his last scans, whole body and bone, we were told the cancer is "stabilized". He is currently on 300 mg of Nubeqa 2x a day (down from 4 x because I asked about it) and Lupron injections every 3 months. We have consciously changed our diet (no added sugar, no alcohol, no processed foods) and he is doing pretty well, although, he does fatigue and sweat easily. My question is whether you believe that taking a couple of your home tests would be beneficial for him? I worry about these powerful drugs he is being given and have noticed a reluctance from the doctor about reducing his drugs any further. Thank you again!                                                Sheena: Hi Dr C! Hope you and your team are well. I recently went for blood work. I fasted for 14 hours and was wondering what your thoughts are specifically regarding my Lipid Panel and Iron Panel. My triglycerides is 1.83, Total 4.05, HDL 1.72 and LDL 1.63 (all mmol/L). For iron my levels are 37 umol/L, iron binding 0.70 umol/L, and ferritin 44 ugL. My Dr says she's concerned with my triglycerides. How can I lower it? And shes concerned with my ferritin and iron levels so shes sending me for a Hemochromatosis blood test to see why the levels are off. (My fasting glucose is 4.9, hbA1c is 5.2, TSH is 1.04 and Auto CBC is 3.8). Would love your thoughts and any food and supplementation recommendations would be appreciated! Love you and all the best to everyone on their health journey!                                                            Madhia: Hello My Dr is giving me a hard time to prescribe MRI for my breast exam. Do you have any Dr you can recommend that would help me in greater Los Angeles area?                                                                                                 Margie: My son, who is 46 years old has had Alpha-Gal for approximately 10 years. Now his wife has also been diagnosed with it. I am aware it is caused by a tick bite. He constantly has mass cell inflammation including breathing and allergy issues. Could you please explain specifically how this disease affects the body's immune system and which of your protocols should be used to bring the body back into balance. Will that particular protocol bring the body back into balance enough so that it will relieve the mass cell inflammation and they can return to eating mammal meat?                                                     Jackie: Hi Dr. Cabral thank you for all that you do. You have made a tremendous impact in my and my clients lives. My husband has just finally been diagnosed after 10 years of misdiagnosis with neurogenic TOS. We have a great rehab team working on the biomechanics and we are exploring Big 5 root causes. I was wondering what natural pain management methods you would recommend during the process pain is 10/10 and conventional medicines wants to basically kill the nerve or put him on Lyrica which neither are an option for us. We are exploring accupuncture, grounding and adrenal sooth/inflammasoothe/cbd protocol. Any other alternative inflammation reduction techniques or devices you would recommend? Could you do a podcast on natural pain management strategies for people with chronic pain?          Thank you for tuning into this weekend's Cabral HouseCalls and be sure to check back tomorrow for our Mindset & Motivation Monday show to get your week started off right! - - - Show Notes and Resources: StephenCabral.com/3495 - - - Get a FREE Copy of Dr. Cabral's Book: The Rain Barrel Effect - - - Join the Community & Get Your Questions Answered: CabralSupportGroup.com - - - Dr. Cabral's Most Popular At-Home Lab Tests: > Complete Minerals & Metals Test (Test for mineral imbalances & heavy metal toxicity) - - - > Complete Candida, Metabolic & Vitamins Test (Test for 75 biomarkers including yeast & bacterial gut overgrowth, as well as vitamin levels) - - - > Complete Stress, Mood & Metabolism Test (Discover your complete thyroid, adrenal, hormone, vitamin D & insulin levels) - - - > Complete Food Sensitivity Test (Find out your hidden food sensitivities) - - - > Complete Omega-3 & Inflammation Test (Discover your levels of inflammation related to your omega-6 to omega-3 levels) - - - Get Your Question Answered On An Upcoming HouseCall: StephenCabral.com/askcabral - - - Would You Take 30 Seconds To Rate & Review The Cabral Concept? The best way to help me spread our mission of true natural health is to pass on the good word, and I read and appreciate every review!  

Ever wondered why a molecule as simple as hydrogen could influence everything from Parkinson's to metabolic syndrome? We explored how molecular hydrogen selectively targets only the most harmful free radicals while leaving beneficial ones alone, making it fundamentally different from every other antioxidant supplement gathering dust in your cabinet.The six-month metabolic syndrome study particularly caught my attention: participants drinking hydrogen water saw improvements in glucose levels, HbA1c, inflammation markers, and even lost weight – with no diet changes or exercise requirements.Tyler breaks down why those expensive alkaline water machines aren't doing what you think (spoiler: it's not about pH), why hydrogen inhalation requires serious safety considerations, and exactly how to dose hydrogen water for maximum benefit.And on top of all this, we tackle why this primordial molecule – literally present since the beginning of the universe – seems almost designed to work with human biology, and why megadoses of vitamins C and E can actually harm exercise performance while hydrogen acts as a fine-tuning modulator.Timestamps:0:00 Hydrogen's effects on major diseases2:45 Six-month metabolic syndrome study results5:15 Hydrogen only targets toxic radicals6:08 Divine properties of hydrogen molecule10:12 Basic chemistry of oxidation and reduction15:30 Dangers of excessive antioxidants23:45 How hydrogen modulates antioxidant systems47:20 Hydrogen production in your gut56:30 Inhaled vs drinking hydrogen water61:15 Explosive dangers of hydrogen inhalation71:30 Therapeutic dosing for hydrogen water85:45 Debunking alkaline and structured water94:30 Tyler's elite athletic performance secretsDisclaimer:Dr. Paul Saladino received his medical degree from the University of Arizona Medical School. His use of "doctor" or "Dr." in relation to himself solely refers to that degree. Dr. Saladino is a licensed physician in California, but he no longer practices in any state and does not see patients so he can focus on educating people full time.This video is for general informational purposes only. It should not be used to self-diagnose and it is not a substitute for a medical exam, cure, treatment, diagnosis, or prescription. It does not create a doctor-patient relationship between Dr. Saladino and you. Always consult your physician before making any health decisions.