Podcasts about hba1c

It's In the News.. a look at the top headlines and stories in the diabetes community. This week's top stories: Eli Lilly will start a lcinical trial for tirzepatide for people with type 1 diabetes, more details on Dexcom's 15 day G7 sensor, Ozepmic pill form tested, type 5 diabetes identified and more! Find out more about Moms' Night Out  Please visit our Sponsors & Partners - they help make the show possible! Learn more about Gvoke Glucagon Gvoke HypoPen® (glucagon injection): Glucagon Injection For Very Low Blood Sugar (gvokeglucagon.com) Omnipod - Simplify Life Learn about Dexcom   Check out VIVI Cap to protect your insulin from extreme temperatures The best way to keep up with Stacey and the show is by signing up for our weekly newsletter: Sign up for our newsletter here Here's where to find us: Facebook (Group) Facebook (Page) Instagram Twitter Check out Stacey's books! Learn more about everything at our home page www.diabetes-connections.com  Reach out with questions or comments: info@diabetes-connections.com Episode transcription with links:   Hello and welcome to Diabetes Connections In the News! I'm Stacey Simms and every other Friday I bring you a short episode with the top diabetes stories and headlines happening now. XX Our top story this week.. Eli Lilly takes the first steps toward getting tirzepatide approved for people with type 1 diabetes. Tirzepatide is sold under the brand names Mounjaro for type 2 and Zepbound for obesity. The main purpose of this study is to find out how well and how safely tirzepatide works in adults who have type 1 diabetes and obesity or are overweight. Participation in the study will last about 49 weeks. Official Title A Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study Evaluating the Efficacy and Safety of Tirzepatide Once Weekly Compared to Placebo in Adult Participants With Type 1 Diabetes and Obesity or Overweight This is a big deal because, even though many people with type 1 are able to get a prescription for tirzepatide, it's not approved for T1D and so insurers won't usually cover it.   https://clinicaltrials.gov/study/NCT06914895 XX The use of drugs like Ozempic, Wegovy and Zepbound in people with type 1 diabetes has risen sharply over the past decade, a new study finds, even though there's little information on the drugs' safety and effectiveness for the condition. The family of medications called GLP-1 receptor agonists includes drugs like Wegovy, Zepbound, Ozempic, Mounjaro and Victoza. But the clinical trials of these medications specifically excluded people with type 1 diabetes, who are dependent on the hormone insulin to survive because they can't make enough of their own. Drugmakers feared that using the GLP-1 medications with insulin might raise the chance of dangerously low blood sugar events, or hypoglycemia, and were unwilling to take the risk of studying them in people with type 1.   For the study, which was published last month in the journal Diabetes, Obesity, and Metabolism, researchers at Johns Hopkins University reviewed the medical records of more than 200,000 people with type 1 diabetes from 2008 to 2023. They grouped the data in three-year periods, starting with October 2008 to September 2011 and ending with October 2020 to September 2023. GLP-1 medication use spiked, as well. Among adults with the highest category of obesity, about 4% used GLP-1 medications in 2008, and 33% did by 2023 – an 800% increase. But these are anecdotal reports and may not reflect instances in which people have side effects or complications like low blood sugar, which can be life-threatening. But Shin says what's really needed is information from randomized, double-blinded studies, in which participants are followed forward in time and given either a drug or a placebo. https://www.cnn.com/2025/04/09/health/glp-1-type-1-diabetes-study/index.html   XX Later this month the FDA will conduct a final meeting regarding a new, investigational compound (sotagliflozin) soda-GLIFF-a-zin that has been shown to Improve QoL and Reduce Long-term Complications for people with type 1 diabetes (T1D). The patient advocacy group Taking Control of Your Diabetes (TCOYD.org) is working to inform the T1D community about sotagliflozin - and to encourage people to sign a Change.org petition directed towards FDA.  Last fall, the FDA declined to approve sotagliflozin due to concerns about a potential increased risk of diabetic ketoacidosis (DKA), despite this being a condition that people with T1D on insulin face and manage daily. While TCOYD respects FDA's caution, the group stands by T1D patients and their physicians who, as a team, balance risks and benefits every day. https://tcoyd.org/petition/ XX Dexcom receives FDA approval for it's G7 with 15 day wear. We have an interview with Chief Operating Officer Jake Leach coming up on Tuesday – we talk about the planned roll out of this sensor, what else has changed, and the fine print in the press release – it says    “A study was conducted to assess the sensor life where 73.9% of sensors lasted the full 15 days. When using the product per package labeling, approximately 26% of sensors may not last for the full 15 days.   https://investors.dexcom.com/news/news-details/2025/Dexcom-G7-15-Day-Receives-FDA-Clearance-the-Longest-Lasting-Wearable-and-Most-Accurate-CGM-System/default.aspx?utm_source=www.diabetech.info&utm_medium=referral&utm_campaign=dexcom-g7-15-day-sensor-gets-fda-cleared-but-will-it-actually-last-that-long   XX Glucotrack is joining something called  FORGETDIABETES bionic pancreas initiative, - this is an European Union project that aims to develop a long-term automated insulin delivery system for type 1 diabetes patients. Glucotrack's Continuous Blood Glucose Monitor (CBGM) will be integrated into the system to provide real-time glucose readings. The initiative's goal is to create a bionic invisible pancreas that eliminates the need for therapeutic actions and reduces psychological burden.   The architecture of BIP encompasses a ground-breaking, lifelong lasting implanted ip glucose nanosensor; a radically novel ip hormone delivery pump, with unique non-invasive hormone refill with a magnetic docking pill and non-invasive wireless battery recharge; an intelligent closed-loop hormone dosing algorithm, optimized for ip sensing and delivery, individualized, adaptive and equipped with advanced self-diagnostic algorithms.     Pump refilling through a weekly oral recyclable drug pill will free T1D subjects from the burden of pain and awkward daily measurement and treatment actions. Wireless power transfer and data transmission to cloud-based data management system round-up to a revolutionary treatment device for this incurable chronic disease. key feature of BIP is to be fully-implantable and life-long lasting thanks to novel biocompatible and immune-optimized coatings guaranteeing long-term safety and stability https://www.stocktitan.net/news/GCTK/glucotrack-to-participate-in-forgetdiabetes-a-prominent-european-cjjldjb0dq7h.html XX A newly recognised form of diabetes, called Type 5, was announced this week at the World Congress of Diabetes 2025. A global task force will investigate this less-understood condition, which differs from Type 1 and Type 2 diabetes. Type 5 diabetes affects people who are underweight, lack a family history of diabetes and do not show the typical symptoms of Type 1 or Type 2 diabetes. The condition was first observed in the 1960s and referred to as J-type diabetes, after being detected in Jamaica. It was classified by the World Health Organisation in 1985, but removed in 1998 due to lack of physiological evidence. At the time, experts believed it to be a misdiagnosed case of Type 1 or 2 diabetes. New research has since confirmed that Type 5 is different. https://economictimes.indiatimes.com/news/new-updates/a-new-type-of-diabetes-has-been-found-by-scientists-and-it-doesnt-show-the-typical-symptoms-of-type-1-or-type-2/articleshow/120276658.cms?from=mdr   XX Oral semaglutide cuts major heart risks in people with type 2 diabetes by 14%, offering a powerful pill-based option. A new clinical trial, co-led by endocrinologist and diabetes specialist John Buse, MD, PhD, and interventional cardiologist Matthew Cavender, MD, MPH, at the UNC School of Medicine, has demonstrated that the oral form of semaglutide significantly lowers the risk of cardiovascular events in individuals with type 2 diabetes, atherosclerotic cardiovascular disease, and/or chronic kidney disease. Results from the rather large, international trial were published in the New England Journal of Medicine and presented at the American College of Cardiology's Annual Scientific Session & Expo in Chicago, Illinois.     The effect of oral semaglutide on cardiovascular outcomes was consistent with other clinical trials involving injectable semaglutide, but more trials are needed to determine if one method may be more effective than the other at reducing major cardiovascular events. https://scitechdaily.com/new-pill-form-of-semaglutide-shows-major-benefits-for-people-with-diabetes/ XX April 14 (UPI) -- The U.S. Food and Drug Administration on Monday warned consumers and pharmacies that fake versions of Ozempic, a drug to treat Type 2 diabetes, have been found in the United States. Novo Nordisk, the Danish-headquartered manufacturer, informed the FDA on April 3 that counterfeit 1-milligram injections of semaglutide were being distributed outside its authorized supply chain. The FDA and Novo Nordisk are testing the fake products to identify whether they're safe. Patients are asked to obtain Ozempic with a valid prescription through state-licensed pharmacies and check the product for any signs of counterfeiting. People in possession of the fake product are urged to call Novo Nordisk customer care at 800-727-6500 Monday through Friday from 8:30 a.m. to 6 p.m. EDT and report it to the FDA's criminal activity division's website. Side effects can be reported to FDA's MedWatch Safety Information and Adverse Event Reporting Program (800-FDA-1088 or www.fda.gov/medwatch) as well as to Novo Nordisk, at 800-727-6500. https://www.upi.com/Health_News/2025/04/14/FDA-fake-Ozempic-drugs-Novo-Nordisk/6841744666854/ XX Can a digital lifestyle modification program reduce diabetes risk? A new study shows that the lifestyle intervention significantly reduced 10-year diabetes risk among prediabetics by nearly 46% and increased the diabetes remission rate, highlighting the importance of lifestyle changes. However, the study was not a randomized trial, and participation in the lifestyle intervention was voluntary, which may introduce selection bias. The study evaluated 133,764 adults, categorizing them as diabetic (7.5%), prediabetic (36.2%), and healthy (56.3%), based on fasting glucose and HbA1c levels. https://www.news-medical.net/news/20250414/Digital-lifestyle-program-cuts-diabetes-risk-by-4625-in-prediabetics-study-of-130k2b-adults-reveals.aspx XX Chrissy Teigan is speaking out about her son's type 1 diagnosis – teaming up with Sanofi to encourage people to screen early for Type 1 diabetes.   Teigen got a crash course in the risks of undiagnosed Type 1 diabetes when her 6-year-old son, Miles, was hospitalized with complications of the autoimmune disease last year. The family knew nothing about Type 1 diabetes when Miles was diagnosed during an unexpected medical emergency, Teigen said in a Tuesday announcement. “We were confused and scared when Miles was first diagnosed,” she said in a statement. “There is no doubt in my mind that knowing in advance would have made a positive impact for Miles, me, and our entire family. I want everyone to hear me when I say: stay proactive and talk to your doctor about getting yourself or your loved ones screened for type 1 diabetes today!”   Teigen shared her family's story in a two-minute video on ScreenForType1.com, a Sanofi website that discusses how to get screened for the condition. Miles' diagnosis made Teigen feel like she “went from a mom to a doctor overnight,” she said. That experience is why Teigen said she is “begging you: Do this one thing, and screen yourself and your family for Type 1 diabetes.” https://www.fiercepharma.com/marketing/sanofi-signs-chrissy-teigen-diabetes-screening-campaign XX Dr. Richard Bernstein – best known for his advocacy around low carb diets for people with diabetes – died this week at the age of 90. Born in 1934 in Brooklyn, New York, he was diagnosed with type 1 at age 12. In the 1970s he adapted a blood glucose monitor for home use and helped pioneer home glucose monitoring. He published multiple books on Diabetes including the #1 selling Diabetes book on Amazon.Com “Dr. Bernstein's Diabetes Solution: A Complete Guide to Achieving Normal Blood Sugars” and “Diabetes Type II: Living a Long, Healthy Life Through Blood Sugar Normalization”.  He practiced and saw patients right up until his death.

Pfizer ends danuglipron clinical program for obesity; FDA warns about counterfeit Ozempic; daily pill shows promise in reducing HbA1c; mavacamten misses in nonobstructive HCM trial and the FDA clears smart belt device reduce fall injury.

In this episode, Tara breaks down why blood work is one of the most powerful tools for navigating your health — especially in perimenopause and midlife. She explains how conventional medicine often relies on lab ranges based on unhealthy population averages, which can leave many women feeling dismissed even when they don't feel well. Instead, Tara advocates for interpreting labs through a functional, optimal range lens, offering a clearer, more personalized picture of what's really happening in your body. She dives into the most important blood markers to monitor annually to protect against risks like dementia, heart disease, osteoporosis, and type 2 diabetes — including fasting insulin, glucose, HBA1C, glycomark, cholesterol ratios, and liver health indicators. Tara also highlights the nuances of thyroid and iron metabolism in midlife, why oversimplified interpretations can lead to missed diagnoses, and how comprehensive reviews can uncover root causes behind symptoms like fatigue, weight gain, and brain fog. This episode is packed with empowering, actionable information to help you advocate for better care, understand your body's signals, and make informed, proactive choices for your health.   What You'll Learn in This Episode: Comprehensive Blood Work Reviews - Discover the difference between a standard blood test review and a deep dive into the nuances of your results. Interpreting Lab Reference Ranges - Learn why the traditional lab ranges might not always reflect the healthiest standards. Key Metabolic Markers - Understand which markers are essential to monitor for optimal metabolic health and why they're critical as we age. Iron and Vitamin D Insights - Find out why relying solely on ferritin for iron levels and high doses of vitamin D might not be the best approach. Thyroid Health Nuances - Explore the complexities behind thyroid markers and why a comprehensive test is more telling.   Your health didn't decline overnight—it took decades of stress, diet choices, and life events to get to this point. True healing requires commitment, patience, and consistency. The women who succeed are the ones who stay the course, even when progress feels slow. If you're ready to commit to deep, lasting change, BOOK A CONSULT WITH TARA HERE.   You may also enjoy these episodes: Episode 123: Caution should be taken when supplementing vitamin D, iron & selenium. Do not DIY these supplements! Episode 22: All about cholesterol, (& how it doesn't cause heart disease).   Mentioned in this episode: EQUIP PRIME PROTEIN – Click HERE to grab yours and use my code: TARA20 to get 20% off HRT Made Simple™ - Learn how to confidently speak to your doctor about the benefits of hormone replacement therapy so you can set yourself up for symptom-free, unmedicated years to come without feeling confused, dismissed, or leaving the medical office minus your HRT script. Hair Loss Solutions Made Simple™ – This course will teach you the best natural, highly effective, and safe solutions for your hair loss so you can stop it, reverse it, and regrow healthy hair without turning to medications. The Hormone Balance Solution™ – My signature 6-month comprehensive hormonal health program for women in midlife who want to get solid answers to their hormonal health issues once and for all so they can kick the weight gain, moodiness, gut problems, skin issues, period problems, fatigue, overwhelm, insomnia, hair/eyebrow loss, and other symptoms in order to get back to the woman they once were. [FREE] The Ultimate Midlife Perimenopause Handbook - Grab my free guide and RECLAIM your confidence, your mood, your waistline and energy without turning to medications or restrictive diets (or spending a fortune on testing you don't need!).  

Diabetes Wake-Up Call: The Silent EpidemicIn this episode of Fat Science, Dr. Emily Cooper, Andrea Taylor and Mark Wright take on a troubling statistic—half of American adults are either diabetic or prediabetic, and for those with prediabetes, 8 in 10 don't know it. Think about your own family. The odds are one in two of your loved ones are at risk.The good news is diagnosing diabetes is easy, and in many cases it's reversible. Dr. Cooper breaks down the tests you should get, the numbers to look for and the top treatments. Taking control of your diabetes risk just could save your life. Key Takeaways:Diabetes affects nearly half of the U.S. population, with approximately 80% of prediabetes cases undiagnosed.Type 1 diabetes requires lifelong insulin therapy, while type 2 is often linked to genetic predisposition and lifestyle, with potential for reversal.Regular screening for glucose (blood sugar) and HbA1c levels (your long-term blood sugar average) is crucial for early detection of prediabetes and diabetes, applicable to both adults and children from age 10.Managing diabetes involves a comprehensive approach, including diet, exercise, lifestyle modifications, and medications like metformin and GLP1's.Medications are not a failure but a crucial tool in preventing severe complications and maintaining a high quality of life.Resources:Connect with Dr. Emily Cooper on LinkedIn.Connect with Mark Wright on LinkedIn.Connect with Andrea Taylor on Instagram.Fat Science is a podcast on a mission to explain where our fat really comes from and why it won't go and stay away. We are committed to creating a world where people are empowered with accurate information about metabolism and recognize that fat isn't a failure. This podcast is for informational purposes only and is not intended to replace professional medical advice.If you have a question for Dr. Cooper, send an email to dr.c@fatsciencepodcast.com. If you have a show idea, feedback, or just want to connect, you can also reach us us at info@diabesityinstitute.org.

Guest: Greg Good, the CEO and Founder of FarmaSea and Sea Veg Whole Food Seaweed supplement.Sea vegetables are packed with protein, iodine, fiber and vitamins A, B, C and E in amounts that are 10 to 20 times higher than land vegetables, while some sea vegetables contain more calcium than milk. Sea lettuce has 25 times the iron found in beef. Which is great for people who can't have beef or prefer not to.An 8-week study of 60 Japanese people revealed that fucoxanthin, a substance in brown seaweed, may help improve blood sugar control.Another substance in seaweed called alginate prevented blood sugar spikes in animals after they were fed a high-sugar meal. It's thought that alginate may reduce the absorption of sugar into the bloodstream.A 2023 meta-analysis Trusted Source found that brown seaweed consumption significantly improved blood glucose, glycated hemoglobin (HbA1c), and Homeostatic Model Assessment of Insulin Resistance (HOMA-IR).Anyone who wants help to feel more natural energy, take a preventative approach to their health, manage the effects of aging, and look to bridge the nutritional gaps currently they're not getting in their daily diet. Check out Superfoodofthesea.com or at 855-627-9929 to ensure that you get the high quality of pure Sea Veg products.Forever Young Listeners for a limited time, you can get 3 bottles of the (90) original Sea veg for $60. Just use the code FY3460 (This is for first time orders only).

The SOUL trial

See all the Healthcasts at https://www.biobalancehealth.com/healthcast-blog If you are receiving testosterone or estradiol hormone pellet therapy, BioBalance Health wants to know if you have any of the following medical conditions that may require you to take antibiotics before any medical or dental procedure that breaks the skin, including pellet insertions and dental cleanings. BioBalance Health is dedicated to providing safe and effective hormone replacement with pellets for both men and women, and we want to ensure your health and safety throughout the process. We use sterile procedure guidelines, but certain conditions still require antibiotics to prevent local infections.   Conditions That May Require Pre-Procedure Antibiotics: If You Have Had a Joint Replacement.Some orthopedic surgeons recommend that patients take antibiotics before dental procedures to prevent infection in the joint that was replaced, while others may not. It is important that you follow the advice of YOUR orthopedic surgeon regarding antibiotics before any procedure. If your orthopedic surgeon has advised you to take antibiotics, please let us know. We can provide you with an antibiotic injection or a prescription to take the day of your pellet insertion that will prevent infection. If You Have Uncontrolled Type 1 or Type 2 Diabetes. If your blood sugar is not well-controlled, you may need antibiotics before your pellet insertion to prevent infection of the pellet insertion area. If you are treated and keep your sugars in good control you may not need antibiotics, however if your diabetes is in poor control, you are more likely to get an infection. It is important that you take antibiotics before your pellet insertion. The following blood sugar levels are considered indicators of poor diabetes control: HbA1c > 9.0 Fasting blood sugar > 150 mg/dL If your blood sugar exceeds these levels, or if your primary care doctor has recommended that you take antibiotics before dental cleanings or procedures, you should also take antibiotics before your pellet insertion to reduce the risk of infection.  If You Have an Autoimmune Disease and are on Immunosuppressive Treatment. If you are receiving treatment for an autoimmune condition that suppresses your immune system, you may be at higher risk for infection at the insertion site. In this case, you will need to take antibiotics before each pellet insertion. If your Rheumatologist does not believe antibiotics are necessary for you, you may proceed without them.  If You Are Receiving Cancer Treatment. Certain cancer treatments, especially those that suppress white blood cell production, can compromise your immune system. If you are undergoing such treatment, you should take antibiotics before or with your pellet insertion to prevent infection.   In Summary: If a doctor has advised you to take antibiotics for procedures, such as dental cleanings, you should also take antibiotics before your pellet insertion. Please inform us of any conditions or treatments that may require this precaution, and we will ensure you are properly prepared for your procedure.

See all the Healthcasts at https://www.biobalancehealth.com/healthcast-blog Last time we reviewed why interpreting your lab may lead you to the wrong diagnosis and treatment.  Today we continue our review of each lab panel and why the reference ranges on your lab results may not be the “Healthy Normal Range” that you should compare your results to. Lab reference ranges are established with a one-size-fits-all mentality, ignoring the numerous variables that influence blood results. Have you ever tried on a “one-size-fits-all “ANYTHING? Those clothes may fit 20% of the population but for the rest of us, the garment doesn't fit our width, weight or height! All one-size-fits-all lab reference ranges are much the same.  For example, the standardized “reference ranges” in the US serve as a one-size-fits-all “ideal range” applied to everyone, despite genetic differences, varying latitudes, and the diverse diets that characterize the American multiethnic population. This presents the first problem with using a single range for all people: variations among individuals based on differing genetic needs.  The second issue is that the ranges on the lab report indicate the minimum levels necessary for survival, not necessarily the healthiest blood levels for most individuals. Another example of one size doesn't fit all is the reference range for women's hormones. A range is displayed for cycling women, but there is no healthy range for menopausal women.  Does the range displayed refer to menopausal women with HRT, or menopausal women without HRT to treat their menopausal symptoms? Is the range based on what is healthy, or what is average? We aren't sure. Labs don't ask patients questions that could help interpret lab values. Therefore, they cannot provide a truly diagnostic reference range for any illness. They only consider gender and age, as reference ranges are solely adjusted for these two factors.  A doctor must interpret individual lab results alongside a patient's medical and surgical history, including established diseases, medications, supplements, hormonal treatments, and past lab values. For instance, laboratory companies should offer reference ranges based on whether a patient is menopausal, a woman is undergoing ERT, a man is receiving testosterone, a patient is on thyroid medication, a person is being treated for diabetes, or the diabetic tests are performed to diagnose diabetes.   Some Reference Ranges are Based on comparing results to Misleading formulas The best example of this issue is the Lipid Panel. Doctors use this panel to determine a person's risk for heart attacks caused by atherosclerosis. Most doctors don't know the formula for determining Total Cholesterol. This test doesn't predict heart disease in most patients, as the formula used to arrive at that number is not indicative of the disease. However, doctors have been advised that when   total cholesterol levels are high, a patient should start taking a statin, a drug that reduces blood cholesterol and sometimes lowers the rate of heart attacks in certain individuals, though it is rarely predictive in 50% of the population. The problem with the lipid panel is twofold: the LDL level indicates future atherosclerosis in only about 50% of the population and is not a specific test for future heart disease risk. Total cholesterol is even less predictive of heart disease because it stems from a flawed formula. Doctors interpret a high Total Cholesterol level as an indication that a patient may be at increased risk for heart disease in the future. When I test patients with elevated Total Cholesterol or high levels of LDL using a Cardiac Calcium Scan to measure plaque, only half of them actually produce plaque, and consequently, are not at risk for atherosclerotic heart disease. I believe that the Total Cholesterol number is derived from an inaccurate formula for determining a person's risk of future heart disease. The Total Cholesterol number is calculated using a flawed equation. The equation is as follows:         LDL + 1/5 Triglycerides+ HDL = Total Cholesterol Total Cholesterol = LDL (bad cholesterol) + 1/5 Triglycerides (high risk factor) + HDL (good cholesterol) Let's examine this formula simply like this:   Bad + Bad + Good does not equal Bad. Due to this incorrect formula, thousands, if not millions, of patients have been prescribed statin drugs for a lifetime without justification!  Statins carry risks. The list of side effects is extensive and includes muscle deterioration and statin-associated dementia. Unfortunately, most people who experience statin side effects are women. Women tend to have higher HDL levels than men. Additionally, they typically do not have atherosclerotic plaque until menopause and usually do not develop it after menopause if they undergo estrogen replacement therapy! This gender issue is just one of the problems with laboratory reference ranges that are not adjusted for sex. The total cholesterol values were developed solely from the blood levels of men, who typically have lower HDL levels. Women were excluded from the tests conducted to create this blood panel. For women, I dispel the myth that high total cholesterol predicts heart disease by recommending a Cardiac Calcium Scan to check for plaque. If a woman has no plaque by the age of 50 and is taking estrogen, she is unlikely to develop plaque in the future.  I still test them every 2-3 years to ensure that no metabolic changes have altered their risk, but I don't put much faith in the unreliable cholesterol blood panel. There is another blood test that has deceptive reference ranges: IGF-1 How about the GH-IGF-1 test, the test for Growth Hormone?  IGF-1 is a metabolite of GH that we can measure to determine how much the patient produces.  This hormone aids in healing and replenishing aging cells in patients after their growth is complete.  The healthy normal range with which I was trained, (150-350 MIU), has been changed to an age-adjusted normal that compares a person to others in her age category who had their blood drawn the previous year.  What is wrong with this? Growth hormone (GH) decreases with age and contributes to the declining health people experience as they grow older. Similarly, IGF-1 diminishes with age and illness, which means that the “reference range” essentially reflects that you are “average for the sick individuals who visit Quest to have their IGF-1 levels checked. ” IGF-1 levels can be enhanced through weight loss, testosterone replacement, and an increase in muscle mass. The current reference range does not indicate health or illness; it merely shows whether you fall within the average for your age group. This non-scientific method of determining “health” is widespread in contemporary medicine. By comparing aging individuals to others within the same age group, for hormones that decline with age, based on samples from sick patients who visit a specific lab in the past year, these labs label patients as “healthy” even when they are as ill as other individuals their age who go to that lab! This practice constitutes age discrimination! Regarding hormones, the levels we maintained during our fertile and youthful years correspond to the blood levels indicative of health in all individuals ages. For example: People who check their IGF-1 (Growth Hormone) levels and see a low “52 ng/ml” might feel satisfied that they are within the standard range (50-280 ng/ml). However, they may not realize that this range applies to older, unhealthy individuals, not to healthy young ones (150-350 ng/ml).  This is just one example of the issues that arise when non-medical individuals, who do not monitor these tests regularly, draw conclusions from the numbers.   Some illnesses require more than one blood test for diagnosis If you consider only one of the three tests for diabetes or prediabetes (Fasting Blood Sugar, HbA1c, and Insulin), you cannot self-diagnose as diabetic, prediabetic, insulin resistance or healthy.  Diabetes is a disease that has coincided with the rising number of obese individuals.  Both conditions affect nearly 50% of the American population. Blood tests cannot be interpreted accurately unless a patient has fasted for 12 hours; all three tests should be evaluated. When diagnosing diabetes and insulin resistance, we perform three tests to assess whether a patient has insulin resistance, prediabetes, or diabetes. These tests guide our diagnosis and inform the treatment we provide based on their results. Fasting insulin is a highly misleading test. Over 15 years ago, a significant study was conducted that was believed to change the reference ranges for fasting insulin.  The new range set for normal fasting insulin was less than 10 mIU/ml. By publishing the reference range less than 18 mIU/ml, they miss diagnosing many patients with insulin resistance HBA1C is a test that gives a value of average blood sugar over three months. The results are often used alone to determine prediabetes and diabetes; however, considering all three aspects makes the diagnosis and treatment plan more specific for the patient. FBS (fasting blood sugar) is the third diabetes test. It is generally used as a screening test that prompts the ordering of the other two blood tests; however, some patients exhibit symptoms of diabetes and insulin resistance without having elevated fasting insulin levels. Many medications can raise diabetic test values, causing a patient to seem diabetic when they are actually experiencing a side effect of the drug.  One such medication is Atorvastatin.  The solution is not treating diabetes but rather adjusting the medication.  Hormone tests are especially challenging to interpret, Especially when testing free Testosterone in women Here are the problems with the free Testosterone test itself: Women have extremely low levels of free testosterone and testosterone compared to men. I have been informed by Quest that women's free testosterone levels are not reliable with current methods because they are not always reproducible when a test is conducted twice on the same day. This leads me to believe that hormone levels do not always reflect the actual blood levels of free testosterone and estradiol. The levels of testosterone in women are based on menopausal levels of T. Women have long been thought to not produce testosterone, so the “normal” levels are quite low, and 0 used to be considered normal- until one day I managed to persuade a medical director at Quest to increase it to 0.2! Women's testosterone is influenced by their production of E2 and E1, which inactivate free T. Women vary in how their cells respond to testosterone and estradiol. Receptor sites and their genetic acceptance of hormones can mean that the same blood level of testosterone in both sexes does not produce the same effects in all patients. Some women (and men) are resistant to E2 and T, or to one of the two. This indicates that the hormone-free T level may be optimal for one woman while being ineffective in alleviating any low T symptoms for another. The latter individual is T resistant, and we currently have no means outside of research labs to determine which women are sensitive and which are resistant. This requires that doctors and NPs look beyond typical reference ranges to effectively manage E2 and T replacement for women. Lastly some labs use the total testosterone level through a formula determine the free T. This carries inherent risks of reporting the wrong active level of testosterone. Total and free testosterone blood levels for men, are derived from results of older men, rather than from the blood levels that indicate health and the levels at which men experience no symptoms. This leads men to believe they are normal, even though they are symptomatic, and they can't get treatment. There is no time to discuss the reference ranges for LH, FSH, Estradiol, and Estrone; these topics will be addressed in a future blog. I hope I have encouraged you to review your blood work with your doctor or Nurse Practitioner, and not to act as your own doctor by interpreting your blood tests.

Let's be real—entrepreneurs love the grind. Late nights, early mornings, endless coffee, and pushing the limits to build the dream. But here's the catch: if your heart isn't in peak condition, all that hustle could be cutting your time short.So, how do you level up your business without sacrificing your health?In this episode of The Happy Hustle Podcast, I sat down with Dr. Stefan Waller, a cardiologist turned health coach, to break down real strategies for optimizing heart health—without the fluff. We're talking about preventing heart disease before it even starts, simple nutrition hacks, and the key health metrics every entrepreneur should track.Dr. Waller emphasizes the importance of knowing your numbers. If you don't track your business finances, you'll go broke, right? Same thing with your health—if you don't track your key metrics, your body might be running on borrowed time.Here are two critical numbers you should be checking regularly:1️⃣ LDL Cholesterol (The Silent Killer)

Episode Summary: When it comes to fat loss, there is no one-size-fits-all approach to carbohydrates. In this episode, we dive into how to personalize your carbohydrate intake based on key factors such as your baseline diet, body composition, activity level, and even your unique blood sugar response. By understanding how your body processes carbs, you can fine-tune your intake for sustainable fat loss and optimal energy levels. Before we get started, grab your copy of my new Fat Loss E-Book! Here's the link. And, head over to my new YouTube channel to subscribe and turn on notifications before the new Carb Series kicks off next week.  What You'll Learn in This Episode: ✔ How to assess your baseline carbohydrate intake before making adjustments ✔ Why muscle mass and body fat percentage impact carb tolerance ✔ The role of activity level in determining your optimal carb intake ✔ How health goals (fat loss, performance, hormone balance) influence carb strategy ✔ Why food sensitivities and individual blood sugar responses matter ✔ Practical strategies for tracking and adjusting your carb intake Key Factors to Consider When Personalizing Carb Intake 1. Your Baseline – Where Are You Starting? Before making changes, assess your current carbohydrate intake. Track what you eat for a few days and consider factors like: Blood sugar response (using a glucometer or continuous glucose monitor) Insulin sensitivity (fasting glucose, HbA1c levels) Energy levels and hunger cues

Welcome to HCPLive's 5 Stories in Under 5—your quick, must-know recap of the top 5 healthcare stories from the past week, all in under 5 minutes. Stay informed, stay ahead, and let's dive into the latest updates impacting clinicians and healthcare providers like you! Interested in a more traditional, text rundown? Check out the HCPFive! New ACP Guidelines Recommend Adding Triptan to NSAID or Acetaminophen for Migraines The American College of Physicians now recommends adding a triptan to NSAIDs or acetaminophen for moderate to severe acute migraines and urges clinicians to initiate combination therapy early. Automated Insulin Delivery Effectively Lowers HbA1c in Type 2 Diabetes  Tandem Diabetes Care's Control-IQ+ automated insulin delivery system led to greater HbA1c reduction than continuous glucose monitoring alone in adults with insulin-requiring type 2 diabetes. FDA Approves Guselkumab (Tremfya) For Crohn's Disease  The FDA approved guselkumab for moderately to severely active Crohn's disease based on phase 3 trial data demonstrating superior efficacy over ustekinumab on endoscopic endpoints. FDA Approves Oral Iptacopan (Fabhalta) as First C3 Glomerulopathy Therapy  The FDA approved iptacopan as the first therapy for C3 glomerulopathy, with phase 3 data showing significant proteinuria reduction and sustained efficacy at 12 months. FDA Approves Vutrisiran (AMVUTTRA) for ATTR-CM  The FDA expanded vutrisiran's approval for cardiomyopathy in transthyretin-mediated amyloidosis, making it the first RNAi therapeutic to reduce cardiovascular mortality and hospitalizations in ATTR-CM.

 In this Episode we shared why Sea vegetables are the most nutritionally dense plants on the planet and the most abundant source of vitamins and minerals in the plant kingdom.  We  highlighted Anti-aging, Energy, and daily nutrition.Guest: Greg Good, the CEO and Founder of FarmaSea and Sea Veg Whole Food Seaweed supplement.Sea vegetables are packed with protein, iodine, fiber and vitamins A, B, C and E in amounts that are 10 to 20 times higher than land vegetables, while some sea vegetables contain more calcium than milk. Sea lettuce has 25 times the iron found in beef. Which is great for people who can't have beef or prefer not to.An 8-week study of 60 Japanese people revealed that fucoxanthin, a substance in brown seaweed, may help improve blood sugar control.Another substance in seaweed called alginate prevented blood sugar spikes in animals after they were fed a high-sugar meal. It's thought that alginate may reduce the absorption of sugar into the bloodstream.A 2023 meta-analysis Trusted Source found that brown seaweed consumption significantly improved blood glucose, glycated hemoglobin (HbA1c), and Homeostatic Model Assessment of Insulin Resistance (HOMA-IR).Anyone who wants help to feel more natural energy, take a preventative approach to their health, manage the effects of aging, and look to bridge the nutritional gaps currently they're not getting in their daily diet. Check out Superfoodofthesea.com or at 855-627-9929 to ensure that you get the high quality of pure Sea Veg products. Forever Young Listeners for a limited time, you can get 3 bottles of the (90) original Sea veg for $60. Just use the code FY3460 (This is for first time orders only).

It's In the News.. a look at the top headlines and stories in the diabetes community. This week's top stories: New drug is looked at for T1D prevention, a new stem cell method is tested for beta cell transplanation without immunosuppresion drugs, the FDA okays the first fast-acting biosimilar insulin, Lilly lowers price of Zepbound, and more! Find out more about Moms' Night Out  Please visit our Sponsors & Partners - they help make the show possible! Learn more about Gvoke Glucagon Gvoke HypoPen® (glucagon injection): Glucagon Injection For Very Low Blood Sugar (gvokeglucagon.com) Omnipod - Simplify Life Learn about Dexcom  Edgepark Medical Supplies Check out VIVI Cap to protect your insulin from extreme temperatures Learn more about AG1 from Athletic Greens  Drive research that matters through the T1D Exchange The best way to keep up with Stacey and the show is by signing up for our weekly newsletter: Sign up for our newsletter here Here's where to find us: Facebook (Group) Facebook (Page) Instagram Twitter Check out Stacey's books! Learn more about everything at our home page www.diabetes-connections.com  Reach out with questions or comments: info@diabetes-connections.com Episode transcription with links:   Hello and welcome to Diabetes Connections In the News! I'm Stacey Simms and every other Friday I bring you a short episode with the top diabetes stories and headlines happening now. XX New research in type 1 diabetes prevention launches. Nektar Therapeutics and TrialNet will evaluate a drug currently used for exzema for patients with new onset stage 3 type 1 diabetes The drug is RezPeg – that's a shortened version of the name (rezpegaldesleukin)   This will be a study of about 70 adults and children and will launch this year. The new study will use a mixed meal tolerance test (MMTT) to measure the efficacy of rezpegaldesleukin or placebo for preserving C-peptide area under the curve over a 12-month duration comprised of a 6-month treatment period and a 6-month follow-up. Secondary objectives include pharmacokinetics, pharmacodynamics, and additional disease assessments including HbA1c levels and patient insulin requirements. Rezpegaldesleukin is being developed as a self-administered injection for a number of autoimmune and inflammatory diseases. https://www.prnewswire.com/news-releases/nektar-announces-clinical-trial-agreement-to-evaluate-rezpegaldesleukin-in-patients-with-new-onset-type-1-diabetes-mellitus-302383052.html XX NLS Pharmaceutics (NLSP) and Kadimastem announced successful completion of a pre-IND meeting with the FDA for iTOL-102, a potential diabetes treatment. iTOL-102 combines Kadimastem's IsletRx cells (stem cell-derived pancreatic islets) with iTolerance's immunomodulator iTOL-100, aiming to cure Type 1 Diabetes without requiring life-long immune suppression. The treatment was evaluated at the Diabetes Research Institute at the University of Miami School of Medicine, where it demonstrated functional insulin release and disease reversal in animal models. Based on FDA feedback, the companies are updating plans for safety toxicology studies and First-in-Human clinical trials. IsletRx is a clinical-grade product comprising human pancreatic islet-like cells capable of secreting insulin, offering a scalable source of insulin-producing cells to address donor islet shortages. The technology can detect glucose levels and produce required amounts of insulin and glucagon.   XX FDA has signed off on a rapid-acting insulin biosimilar for the first time. The agency has given a thumbs up to Sanofi's Merilog (insulin-aspart-szjj) as the first biosimilar to Novo Nordisk's NovoLog for patients with diabetes. Merilog will be provided by prefilled pen in a 3 mL dose or in a multiple-dose 10 mL vial. It is for adults and pediatric patients age 6 and older.     NovoLog and Novo Nordisk's other rapid-acting insulin follow-on Fiasp are among the drugs subject to government price negotiations under the Inflation Reduction Act. The new prices will be enacted at the start of next year. In July 2021, the FDA approved Biocon and Viatris' Semglee (insulin glargine-yfgn) as the first biosimilar to Lantus. Five months later, the U.S. regulator endorsed Eli Lilly's version of the drug, called Rezvoglar (insulin glargine-aglr). https://www.fiercepharma.com/pharma/fda-signs-sanofis-biosimilar-first-novo-nordisks-rapid-acting-novolog XX Eli Lilly said Tuesday that it will offer more doses of its obesity drug Zepbound in vials and lower the prices of the doses it already sells, as the pharma giant seeks to draw patients away from cheap, compounded copies of weight loss medications. The company launched 7.5 mg and 10 mg vials of tirzepatide, sold under the brand name Zepbound, which typically cost $599 and $699, respectively. However, they are now available for $499 per month for patients paying without insurance. This applies to the first fill and all refills that are delivered every 45 days. Additionally, the company lowered the prices of the 2.5 mg and 5 mg vials to $349 and $499 per month, respectively. The company, which has seen a significant boost in profits from Zepbound and Mounjaro – essentially the same drug with different FDA-approved uses – announced that the new vials and pricing are exclusively available through the company's self-pay pharmacy, LillyDirect Self Pay Pharmacy Solutions. https://www.bloomberg.com/news/articles/2025-02-25/zepbound-cost-for-vials-cut-to-battle-cheaper-copycats XX Medicare spending on 10 diabetes drugs, including popular GLP-1s, more than quadrupled over a five-year period and could reach $102 billion next year, an analysis by Health and Human Services' inspector general found. The findings also come as the Trump administration weighs the fate of a Biden administration proposal that would require Medicare and Medicaid to cover GLP-1s for weight loss. The biggest spikes in usage were for Rybelsus, Novo Nordisk's once-daily GLP-1 tablet, and for the company's weekly injectable Ozempic, whose spending about doubled every year under review. https://www.axios.com/2025/02/25/medicare-spending-surge-diabetes-drugs XX Tandem Diabetes Care has secured a new FDA clearance for its insulin dose-calculating algorithm, opening up Control IQ for use in adults with Type 2 diabetes. The expanded label was based on data from a pivotal, randomized trial of more than 300 people with Type 2 diabetes, comparing its use to manual multiple daily injections. Tandem said it plans to present the study's results at the annual Advanced Technologies & Treatments for Diabetes meeting scheduled for next month in Amsterdam. https://www.fiercebiotech.com/medtech/tandem-diabetes-care-insulin-dosing-algorithm-nets-fda-clearance-type-2-diabetes XX Drugs approved for diabetes and obesity might be useful for the treatment of cognitive and mental health disorders, according to a new paper published in Nature Mental Health.   The study reviewed and integrated data from both preclinical and clinical studies to gather evidence on the possible effects of these drugs GLP1s and semaglutide  in conditions such as dementia, substance use disorders, psychotic disorders, mood and anxiety disorders, and eating disorders.     The study found promising but still preliminary evidence that GLP-1RAs could be beneficial over a range of cognitive and mental health disorders. These drugs have shown potential in improving cognition, reducing addictive behavior, and alleviating depression and anxiety. More data from robustly designed studies (i.e., randomized controlled trials) are needed to better understand GLP-1RAs' prospective efficacy and safety profile, especially with long-term use. https://medicalxpress.com/news/2025-02-diabetes-drugs-mental-health-treatment.html XX The FDA  issued draft guidance that includes recommendations to support the development and marketing of safe and effective AI-enabled The guidance, if finalized, would be the first guidance to provide comprehensive recommendations for AI-enabled devices throughout the total product lifecycle, providing developers with an accessible set of considerations that tie together design, development, maintenance, and documentation recommendations to help ensure the safety and effectiveness of AI-enabled devices. FDA is requesting public comment on this draft guidance by April 7. The agency also released draft guidance for the use of AI to support regulatory decision-making for drug and biological products. https://www.mddionline.com/artificial-intelligence/fda-issues-draft-guidance-for-ai-enabled-devices-seeks-public-feedback XX Congrats to Mila Clarke who some of you may know better as Hangry Woman on social. She has developed a great app called Glucose Guide and the Nutrition Assistant portion of that app went live this week. Glucose Guide is a web and mobile app that offers diabetes meal tracking, coaching, resources, recipes and community to those looking for help managing diabetes. MEAL AND BLOOD SUGAR TRACKING FEATURES.

In this episode of Diabetes Dialogue: Technology, Therapeutics, & Real-World Perspectives, hosts Diana Isaacs, PharmD, an endocrine clinical pharmacist, director of Education and Training in Diabetes Technology, and codirector of Endocrine Disorders in Pregnancy at the Cleveland Clinic, and Natalie Bellini, DNP, program director of Diabetes Technology at University Hospitals Diabetes and Metabolic Care Center, discuss a pair of recently published studies examining the use of diabetes technology in adults with type 2 diabetes. SECURE-T2D A single-arm prospective study conducted at 21 US clinical centers, SECURE-T2D assessed the impact of automated insulin delivery (AID) on glycemic control in adults with type 2 diabetes using insulin for at least 3 months. The study enrolled 305 participants (mean age, 57 years; 57% female), with a diverse racial and ethnic representation, including 24% Black and 22% Hispanic or Latino. Following a 14-day standard therapy phase, participants used the Omnipod 5 AID system for 13 weeks. HbA1c decreased from 8.2% (SD, 1.3) at baseline to 7.4% (SD, 0.9) (mean difference, -0.8 percentage points; 95% CI, -1.0 to -0.7; P

Join us for a fascinating conversation with Dr. Eric Westman, a leading expert in the field of ketogenic diets. With over 25 years of experience, Dr. Westman shares his insights on the power of ketogenic approaches, including his experience using them to improve the health and weight of his own patients for nearly 3 decades. We delve into the science behind these diets, exploring their benefits and potential drawbacks. Dr. Westman also clarifies the connection between carnivore diets and ketogenic diets, offering his perspective and insights. Whether you're curious about keto, considering a carnivore lifestyle, or simply looking to improve your health, this episode is packed with valuable information you won't want to miss! Professor Eric Westman Links: Dr. Westman free diabetes LAB workshop: February 10:

In this Q&A episode, I'm answering some of the most common questions that land in my DMs! From the best ways to support your baby's gut health after a C-section to natural strategies for lowering HbA1c and optimizing metabolic health, I'm covering it all. Plus, I dive into the hot topic of sauna use during pregnancy—what's safe, what's not, and my personal experience. Want your question answered in a future episode? Send me a DM on Instagram!   I TALK ABOUT:  04:00 – Supporting my baby's gut health after a C-section 07:30 – Debunking myths about vaginal seeding and vaginal swabbing for C-section babies 14:00 – The importance of immediate skin-to-skin contact after birth 18:00 – Tiny Health's at-home microbiome test for babies and moms (code: BIOHACKINGBRITTANY) 20:00 – The best probiotics for newborn gut health (Evivo, BioGaia) 23:00 – Introducing prebiotic and probiotic-rich foods when starting solids 26:00 – How to lower HbA1c naturally through nutrition and movement 32:00 – The best supplements for optimizing insulin sensitivity 35:00 – Why sleep and stress management are key to metabolic health 37:00 – Sauna use during pregnancy 42:00 – My personal experience with sauna use while pregnant   SPONSORS: Protect your reproductive health with Leela Quantum Tech's EMF-blocking underwear. Use code: BIOHACKINGBRITTANY for an extra 10% discount on all of their products!   RESOURCES: Optimize your preconception health by joining my Baby Steps Course today! Optimize your preconception health and fertility through my free hormone balancing, fertility boosting chocolate recipe! Download it now! My Amazon storefront LET'S CONNECT: Instagram, TikTok, Facebook Shop my favorite health products Listen on Spotify, Apple Podcasts, YouTube Music

In this Episode we will share why Sea vegetables are the most nutritionally dense plants on the planet and the most abundant source of vitamins and minerals in the plant kingdom.  We will highlight Energy, and daily nutrition.To help us do the heavy lifting we have invited Greg Good, the CEO and Founder of FarmaSea and Sea Veg Whole Food Seaweed supplement.Sea vegetables are packed with protein, iodine, fiber and vitamins A, B, C and E in amounts that are 10 to 20 times higher than land vegetables, while some sea vegetables contain more calcium than milk. Sea lettuce has 25 times the iron found in beef. Which is great for people who can't have beef or prefer not to.An 8-week study of 60 Japanese people revealed that fucoxanthin, a substance in brown seaweed, may help improve blood sugar control.Another substance in seaweed called alginate prevented blood sugar spikes in animals after they were fed a high-sugar meal. It's thought that alginate may reduce the absorption of sugar into the bloodstream.A 2023 meta-analysis Trusted Source found that brown seaweed consumption significantly improved blood glucose, glycated hemoglobin (HbA1c), and Homeostatic Model Assessment of Insulin Resistance (HOMA-IR).Anyone who wants help to feel more natural energy, take a preventative approach to their health, manage the effects of aging, and look to bridge the nutritional gaps currently they're not getting in their daily diet. Check out Superfoodofthesea.com or at 855-627-9929 to ensure that you get the high quality of pure Sea Veg products.For Forever Young Listeners for a limited time, you can get 3 bottles of the (90) original Sea veg for $60. Just use the code FY3460 (This is for first time orders only).

This week on Fuel for the Sole, we discuss a new research paper about heavy metals found in protein powders, and answer a bunch of listener questions, including:  If athletes have higher HbA1c than the general public  Which electrolytes you should be taking  The importance of third party testing  How to fuel on the bike  A whole lot more!  Want to be featured on the show? Email us at⁠ fuelforthesolepodcast@gmail.com⁠.  This episode is fueled by ASICS and RNWY! Head over to⁠ ASICS.com⁠ and sign up for a OneASICS account. It's completely free and when you sign up you will receive 10% off your first purchase. You also gain access to exclusive colorways on ASICS.com, free standard shipping, special birthday month discounts and more. We've been using RNWY Collagen and loving it. Head over to ⁠https://rnwy.life/⁠ and use code FEATHERS15 for 15% off your purchase. 

Chlorhexidine and Diabetes: Effects of Mouthwash on Periodontal Pathogens and HbA1c Levels By Today's RDH Research Original article published on Today's RDH: https://www.todaysrdh.com/chlorhexidine-and-diabetes-effects-of-mouthwash-on-periodontal-pathogens-and-hba1c-levels/ Need CE? Start earning CE credits today at ⁠⁠⁠⁠https://rdh.tv/ce⁠⁠⁠⁠  Get daily dental hygiene articles at ⁠⁠⁠⁠https://www.todaysrdh.com⁠⁠⁠⁠ Follow Today's RDH on Facebook: ⁠⁠⁠⁠https://www.facebook.com/TodaysRDH/⁠⁠⁠⁠ Follow Kara RDH on Facebook: ⁠⁠⁠⁠https://www.facebook.com/DentalHygieneKaraRDH/⁠⁠⁠⁠ Follow Kara RDH on Instagram: ⁠⁠⁠⁠https://www.instagram.com/kara_rdh/

Ads for Ozempic, Wegovy, and Zepbound are all over our televisions (at least here in the US). But are these injectables really the key to losing weight and keeping it off? In this episode, I'm digging into all of the science surrounding these popular weight-loss drugs, including - the differences between each of them - how they work (and don't work) - the unwanted side effects that come from using these medications - natural ways to increase your body's production of GLP-1 ... and more! --- Show Notes: References: Coursework from Master's in Human Nutrition & Functional Medicine Program at the University of Western States Efficacy and safety of GLP-1 receptor agonists versus SGLT-2 inhibitors in overweight/obese patients with or without diabetes mellitus: a systematic review and network meta-analysis Weight regain and cardiometabolic effects after withdrawal of semaglutide: The STEP 1 trial extension Weight Loss Medications: GLP-1 Agonists and How They Work How Much Does Ozempic Cost? With & Without Insurance Zepbound vs. Ozempic: 5 Differences Between These Weekly Injections What Are Incretin Mimetics, and How Do They Affect Weight Loss, Blood Sugar, and Type 2 Diabetes? Strategies for minimizing muscle loss during use of incretin‐mimetic drugs for treatment of obesity The Positive Effects of Yerba Maté (Ilex paraguariensis) in Obesity Anti-obesity effects of Yerba Mate (Ilex Paraguariensis): a randomized, double-blind, placebo-controlled clinical trial The effect of psyllium on fasting blood sugar, HbA1c, HOMA IR, and insulin control: a GRADE-assessed systematic review and meta-analysis of randomized controlled trials Soluble fibers from psyllium improve glycemic response and body weight among diabetes type 2 patients (randomized control trial) Increased glucagon-like peptide-1 secretion may be involved in antidiabetic effects of ginsenosides Modulation of glucagon-like peptide-1 release by berberine: in vivo and in vitro studies The effects of berberine on inflammatory markers in Chinese patients with metabolic syndrome and related disorders: a meta‑analysis of randomized controlled trials Berberine is a novel cholesterol-lowering drug working through a unique mechanism distinct from statins A High Dose of Dietary Berberine Improves Gut Wall Morphology, Despite an Expansion of Enterobacteriaceae and a Reduction in Beneficial Microbiota in Broiler Chickens Berberine enhances the AMPK activation and autophagy and mitigates high glucose-induced apoptosis of mouse podocytes Curcumin induces secretion of glucagon-like peptide-1 through an oxidation-dependent mechanism --- 135: What You Should Know Before Starting Ozempic Sign up for a 1:1 Discovery Call Join the Compass Method DIY Program Jump inside my Rock the Bloat Minicourse Get my Core-Gi Workout Program with the exclusive listener discount! Join my Brain Rewiring Masterclass You can learn more about me by following on IG @imperfectlypaigewellness or by checking out my blog, freebies, and offers on my website: https://imperfectlypaigewellness.com Please share with #PaigeTalksWellness to help get the word out about the show - and join the Imperfect Health Fam over on Facebook.

Pre-diabetes marks the initial phase of diabetes. A fasting blood sugar level below 110 mg/dL is considered normal. If it ranges from 110 to 126 mg/dL, you are classified as pre-diabetic. The Oral Glucose Tolerance Test (OGTT) involves consuming 75 grams of glucose, followed by a blood sugar test two hours later. A result below 140 mg/dL is normal, while a range of 140 to 199 mg/dL indicates pre-diabetes. Additionally, HbA1c levels provide long-term insights into blood sugar control. Levels below 5.7% is normal, 5.7% to 6.4% indicate pre-diabetes, and 6.5% or higher signify diabetes. All people with diabetes cases progress through the pre-diabetes stage. World Diabetes Day and Awareness World Diabetes Day is celebrated on November 14th, coinciding with the birthday of Frederick Banting, the discoverer of insulin. This global initiative, led by the International Diabetes Federation, promotes awareness with an annual theme. The 2024–2026 theme focuses on Diabetes and Well-Being, and the 2024 sub-theme emphasizes Breaking Barriers, Bridging Gaps, highlighting the importance of a fulfilling life alongside managing diabetes. Gestational Diabetes and Pregnancy Hormones During pregnancy, placental hormones like human placental lactogen, (HPL), progesterone and estrogen increase insulin resistance by over 50%, impairing insulin's effectiveness. Typically, if someone's pancreas is producing about 50 units of insulin daily, during pregnancy, it may need 75–80 units per 24hr. If beta cells cannot meet this increased demand of pregnancy, blood sugar levels rises, leading to gestational diabetes. A glucose challenge test with 75 grams of glucose, followed by a blood sugar measurement after two hours, acts as a stress test for beta cell function. Levels below 140 mg/dL are normal, while levels above 140 indicate gestational diabetes. Early detection and management are crucial to ensure a healthy baby's birth. Recorded on: 8.11.2024 Recorded at: Akashwani Nagpur

Introducing Blood sugar hacks to give you more energy | Glucose Goddess Jessie Inchauspé and Prof. Tim Spector from ZOE Science & Nutrition.Follow the show: ZOE Science & Nutrition Why do some people feel fine eating lots of carbs when others feel energy slumps? Is blood sugar to blame?In this episode, we learn why blood sugar varies so much between people, and the tools to manage these levels. Tim Spector and Jessie Inchauspé (aka the Glucose Goddess) will discuss the latest science around glucose control, what the cool new device on the block – the CGM – can tell us and why blood sugar levels are only one part of the picture of our health.Jessie is a bestselling author and science communicator with a community of over 5 million followers. Tim is a professor of epidemiology at King's College London and ZOE's scientific co-founder.

Alle Informationen zur Carnivoren Ernährung unter www.carnitarier.de. Herzlichen Dank an unsere WERBEPARTNER: https://www.carnivoro.eu/collections/all-products: Supplemente rund um die Carnivore Ernährung Mit dem Gutscheincode CARNITARIER erhältst du 10 % Rabatt auf deinen ersten Einkauf! Affiliate Link: www.carnivoro.eu/carnitarierin https://www.kaufnekuh.de/de: Fleisch aus artgerechter Haltung mit fairen Preisen für Landwirte Mit dem Gutscheincode CARNITARIER erhältst du 10 € Ermäßigung auf deinen Einkauf ab 50 €. _____________________________________________________________Q & A with Dr. Shawn Baker, Dr. Elke Lorenz and Dr. Rainer Klement A live interview from the Medical Conference in Baden-Baden with Dr. Shawn Baker, Dr. med. Elke Lorenz an Dr. Rainer Klement on questions from our followers.  How do cardiologist colleagues react to Dr. Lorenz, who recommends Keto and Carnivore? How many CT-scans are ok if you don't want too much radiation? Do we need extra aids to detoxify from heavy metals? Are exogenous ketones a natural supplement? Can epilepsie or glyosis be healed with carnivore? How quick can ferritin levels rise on the carnivore diet?And how long does it take to reduce HbA1C-values?  What about Carnivore and dementia? Do antibodies decrease on Carnivore no matter what you eat on Carnivore? Should we always have a heart CT scan if we have high LDL cholesterol? Is a ketogenic diet good for everyone? Should pregnant women follow cravings for carbs? Is raw meat better to digest? Are there any contraindications to Carnivore? Do you need to eat organs on a Carnivore diet?  ___________________________________________________________Fleischzeit ist der erste deutschsprachige Podcast rund um die carnivore Ernährung. Hier erfahrt ihr Tipps zur Umsetzung des carnivoren Lifestyles, wissenschaftliche Hintergründe zur Heilsamkeit sowie ökologische und ethische Informationen zum Fleischkonsum. Eine Übersicht über alle Folgen findet ihr hier: www.carnitarier.de/fleischzeitpodcast Andrea Siemoneit berichtet nach über drei Jahren carnivorer Ernährung über ihre Erfahrungen und Erkenntnisse. Außerdem interviewt sie andere Carnivoren und Wissenschaftler. Ihr findet sie auf Instagram unter https://www.instagram.com/carnitarierin/ Handbuch der Carnivoren Ernährung: https://carnitarier.eu/collections/bucher  Haftungsausschluss:Alle Inhalte im Podcast werden von uns mit größter Sorgfalt recherchiert und publiziert. Dennoch übernehmen wir keine Haftung für die Richtigkeit, Vollständigkeit oder Aktualität der Informationen. Sie stellen unsere persönliche subjektive Meinung dar und ersetzen auch keine medizinische Diagnose oder ärztliche Beratung. Dasselbe gilt für unsere Gäste. Konsultieren Sie bei Fragen oder Beschwerden immer Ihren behandelnden Arzt.

It's In the News.. a look at the top headlines and stories in the diabetes community. This week's top stories: Mannkind releases info about it's Afrezza pediatric studies, Dexcom launches AI tech with Stelo, Health Canada approves Tandem/Dexcom G7, diabetes drug may help sleep apnea, an app in development to help drivers with T1D and more! Find out more about Moms' Night Out  Please visit our Sponsors & Partners - they help make the show possible! Learn more about Gvoke Glucagon Gvoke HypoPen® (glucagon injection): Glucagon Injection For Very Low Blood Sugar (gvokeglucagon.com) Omnipod - Simplify Life Learn about Dexcom  Edgepark Medical Supplies Check out VIVI Cap to protect your insulin from extreme temperatures Learn more about AG1 from Athletic Greens  Drive research that matters through the T1D Exchange The best way to keep up with Stacey and the show is by signing up for our weekly newsletter: Sign up for our newsletter here Here's where to find us: Facebook (Group) Facebook (Page) Instagram Twitter Check out Stacey's books! Learn more about everything at our home page www.diabetes-connections.com  Reach out with questions or comments: info@diabetes-connections.com Episode transcription with links: Hello and welcome to Diabetes Connections In the News! I'm Stacey Simms and every other Friday I bring you a short episode with the top diabetes stories and headlines happening now. XX Mannkid expects to talk to the FDA about Afrezza inhaled insulin for pediatric approval early in 2025. The company just announced six-month results from its Phase 3 INHALE-1 study of kids aged 4-17 with type 1 or type 2 diabetes comparing either inhaled pre-meal insulin or multiple daily injections (MDI) of rapid-acting insulin analog, both in combination with basal insulin. A 26-week extension phase in which all remaining MDI patients were switched to inhaled insulin is ongoing. HbA1c change over 26 weeks exceeded the prespecified non-inferiority margin of 0.4% (0.435%), largely driven by the variability of a single patient who did not adhere to the study protocol. A modified ITT (mITT) analysis, which excluded this subject, did not exceed the predetermined threshold of 0.4% (0.370%), thereby establishing the non-inferiority of Afrezza to MDI, which was the primary endpoint of the study. Over 26 weeks of treatment, there were no differences in lung function parameters between the treatment groups, There were no differences between groups or concerns in other safety measures, including hypoglycemia. https://www.medscape.com/viewarticle/inhaled-insulin-benefits-kids-diabetes-too-2024a1000nex   XX Dexcom announces the use of AI for its Stelo platform. The company says the new Dexcom GenAI platform will analyze individual health data patterns to reveal a direct association between lifestyle choices and glucose levels while providing actionable insights to help improve metabolic health. Stelo users will start seeing the features this week. The AI is modeled after Google Cloud's Vertex AI and Gemini models. We'll hear more about this in January – Dexcom will be part of a panel at the Consumer Electronics Show about AI and healthcare. BTW this press release is the first time I've seen what seems to be a new slogan for Dexcom – Discover What You're Made Of. https://www.businesswire.com/news/home/20241217011997/en/Dexcom-Launches-the-First-Generative-AI-Platform-in-Glucose-Biosensing XX Staying with Dexcom, users report that the geofencing issue we reported on seems to be resolved. Previously, if you had an issue with Dexcom G7 outside of your home country, you couldn't reinstall or use the app without customer support. With the latest iOS and Android G7 apps, this seems to be resolved. This is according to the folks in the DIY community who first brought it to my attention.   XX Interesting insulin development to watch. Egypt approves EVA Pharma's insulin drug products, which is a collbaration between Eli llly and EVA, an Egyptian company. The Egyptian Drug Authority approved the insulin glargine injection manufactured by EVA Pharma through a collaboration with Eli Lilly and Company (NYSE: LLY). Launched in 2022, the collaboration aims to deliver a sustainable supply of high-quality, affordable human and analog insulin to at least one million people annually living with type 1 and type 2 diabetes in low- to middle-income countries (LMICs), most of which are in Africa.   Lilly has been supplying its active pharmaceutical ingredient (API) for insulin to EVA Pharma at a significantly reduced price and providing pro-bono technology transfer to enable EVA Pharma to formulate, fill and finish insulin vials and cartridges. This collaboration is part of the Lilly 30x30 initiative, which aims to improve access to quality health care for 30 million people living in resource-limited settings annually by 2030. https://www.prnewswire.com/news-releases/lilly-and-eva-pharma-announce-regulatory-approval-and-release-of-locally-manufactured-insulin-in-egypt-302333269.html     XX Can we add treating sleep apnea to the list of applications for terzepatide? That's the generic for Zepbound and Mounjaro. Phase 3 study shows that 10- and 15-milligram injections of Zepbound "significantly reduced the apnea-hypopnea index" among those who have obesity and moderate-to-severe obstructive sleep apnea. Eli Lilly said there was nearly a 20% reduction in weight among those in the trials. The company said it plans to submit its findings to the Food and Drug Administration and other global regulatory agencies beginning mid-year. https://www.aol.com/popular-weight-loss-drug-could-131507702.html   XX Health Canada okays Tandem's tslim X2 with Dexcom G7 and G6 making it the first and only insulin pump in Canada that is integrated with both Dexcom sensors. Now, t:slim X2 users in Canada can experience even more choice when it comes to CGM compatibility, along with the option to spend more time in closed loop with Dexcom G7's 30-minute sensor warm-up time, faster than any other CGM on the market.3 In addition, t:slim X2 users who pair Dexcom G7 with an Apple smartwatch4 can see their glucose numbers directly from their watch without having to access their pump or smartphone4. Tandem will email all in-warranty t:slim X2 users in Canada with instructions on how to add the new compatibility feature free of charge via remote software update. t:slim X2 pumps pre-loaded with the updated software will begin shipping to new customers in early January 2025.   To check coverage and start the process of getting a Tandem insulin pump, please visit tandemdiabetes.ca. https://www.businesswire.com/news/home/20241210731189/en/Tandem-tslim-X2-Insulin-Pump-Now-Compatible-with-Dexcom-G7-CGM-in-Canada XX A federal jury on Tuesday awarded Insulet $452 million in its patent skirmish with EOFlow over insulin patch pumps. The jury awarded Insulet $170 million in compensatory damages from EOFlow and an additional $282 million in exemplary damages for willful and malicious misappropriation. A judge has not yet entered a judgment on the decision. Insulet filed a lawsuit in the U.S. District Court for the District of Massachusetts in 2023, claiming EOFlow copied patented components of its Omnipod insulin pumps. In October 2023, the Massachusetts district court issued a preliminary injunction against EOFlow. Following that decision, Medtronic called off plans to buy EOFlow for about $738 million.   A federal appeals court later overturned the preliminary injunction, and EOFlow resumed selling its devices in Europe. The company recently defended against a separate injunction filed by Insulet in Europe's Unified Patent Court, according to Korea Biomedical Review, an online English newspaper based in Seoul, South Korea.   The Massachusetts jury found this week that EOFlow and CEO Jesse Kim, as well as two of three former Insulet employees who were named as defendants in the lawsuit, misappropriated Insulet's trade secrets.   Insulet CEO Jim Hollingshead said the company is “extremely pleased with the jury's verdict.” EOFlow did not immediately respond to a request for comment. https://www.medtechdive.com/news/insulet-eoflow-jury-verdict-patent-lawsuit/734745/ XX A tele-education program for health care providers who treat people with diabetes resulted in significant improvements in patient outcomes, including better blood sugar levels and increased use of medical devices to manage the disease, a University of Florida study finds. Led by researchers in the UF College of Public Health and Health Professions and the UF College of Medicine, the program used the Extension for Community Health Care Outcomes model, which has been adopted worldwide to train clinicians who treat patients with a variety of conditions. Known as Project ECHO, this is one of the first to demonstrate patient benefits for the program in a large, randomized trial. The findings appear in the journal Diabetes Care. https://ufhealth.org/news/2024/clinician-training-program-leads-to-better-outcomes-for-patients-with-diabetes XX New app under development to make driving safer for people with diabetes. Diabetes Driving Pal says it will use CGM data and guide you while you are driving without any annoying alerts. Guidance/suggestions will be on your car dashboard so that you don't have to look at phone and it will be very individualized and actionable. In a study last year, ~70% of people have reported (5% reported accident) to have at least one low blood sugar while driving and most reported that CGM alerts were not enough to protect them. We are hoping to start beta testing in a few months. We are trying to raise the fund to develop this product. We need your support. For more information, please visit: https://lnkd.in/gTDhnDc4 XX I'm also going to link to the top ten most read diabetes and endocrinology stories of 2024 from Medscape. This is almost all GLP-1 related.. and mostly for people with type 2. https://www.medscape.com/viewarticle/icymi-top-10-diabetes-endocrinology-stories-2024-2024a1000n6u?&icd=login_success_email_match_fpf XX That's it for the last In the News of 2024! Don't miss out episode next week with a look ahead to what we're watching in 2025. I'm SS I'll see you back here soon…

In this Episode we will share why Sea vegetables are the most nutritionally dense plants on the planet and the most abundant source of vitamins and minerals in the plant kingdom.  We will highlight Energy, and daily nutrition.]To help us do the heavy lifting we have invited Greg Good, the CEO and Founder of FarmaSea and Sea Veg Whole Food Seaweed supplement.Sea vegetables are packed with protein, iodine, fiber and vitamins A, B, C and E in amounts that are 10 to 20 times higher than land vegetables, while some sea vegetables contain more calcium than milk. Sea lettuce has 25 times the iron found in beef. Which is great for people who can't have beef or prefer not to.An 8-week study of 60 Japanese people revealed that fucoxanthin, a substance in brown seaweed, may help improve blood sugar control.Another substance in seaweed called alginate prevented blood sugar spikes in animals after they were fed a high-sugar meal. It's thought that alginate may reduce the absorption of sugar into the bloodstream.A 2023 meta-analysis Trusted Source found that brown seaweed consumption significantly improved blood glucose, glycated hemoglobin (HbA1c), and Homeostatic Model Assessment of Insulin Resistance (HOMA-IR).Anyone who wants help to feel more natural energy, take a preventative approach to their health, manage the effects of aging, and look to bridge the nutritional gaps currently they're not getting in their daily diet.Check out Superfoodofthesea.com or at 855-627-9929 to ensure that you get the high quality of pure Sea Veg products.For Forever Young Listeners for a limited time, you can get 3 bottles of the (90) original Sea veg for $60. Just use the code FY3460 (This is for first time orders only).

Cisco, the worldwide leader in networking and security, today announced a joint initiative with the University of Galway and CÚRAM, SFI Research Centre for Medical Devices in Ireland, to create a research framework for the world's first 'Virtual Hospital', serving patients with diverse conditions at every stage of their healthcare needs. As part of the Cisco Country Digital Acceleration (CDA) programme, the initiative, which is already in pilot, is aligned with the ambitions of Ireland's 10-year health and social care reform Sláintecare, to avoid unnecessary hospital admission and support patients at home. The objectives of this initiative, powered by Cisco technology, are to help increase access to services, convenience, and improve outcomes for patients. It will also seek to provide patients the ability to play an active role in their own recovery. The virtual platforms are designed to mean patients will not only be able to monitor their progress, but also provide patients direct access to educational materials, and the ability to participate in the decision-making process with their healthcare providers. Unlike other initiatives around the world that deliver individual specialty virtual wards, this initiative brings together multiple clinical areas and stages of treatment to provide seamless care. These include community virtual care pathways for enhanced monitoring of chronic conditions such as COPD to enable admission avoidance. In addition, it is enabling virtual outpatient clinics for remote appointments with integrated multiparameter diagnostics. Delivering virtual care Cisco technologies, including networking, cybersecurity, Webex devices, and application visibility solutions, are delivering mission-critical digital infrastructure to power operations, connecting patients with their healthcare providers, wherever they may be, and ensuring reliable mobile data connectivity for seamless virtual care. Underpinned by Cisco networking infrastructure, myPatientSpace, and patient power mobile health apps provide the virtual hospital's digital platform that helps patients track key health metrics and monitor symptoms from home. Clinicians will connect to real-time dashboards that display information on a patient's condition, alerting medical professionals to changes so they can detect deterioration early and deliver timely care. Initial feedback from patients during the setup of the initiative has been highly positive with comments including: "You're not having to travel to go to a consultant, and they can do it from their office as well… you have the GP on it, and another doctor too. For me, that's a complete positive"; "all my information from the monitoring was there in front of me on the screen. I found it all very useful, and in some way better than in person." The University of Galway HIVE Lab has developed a range of digital care solutions for local patients in this groundbreaking study, enabled by Cisco technology such as Webex integrated Virtual Consultations. The initiative is using innovative AI technology such as dynamic appointments where patients with chronic diseases are automatically triaged to an appropriate outpatient clinic slot based on their clinical need (e.g. Blood Pressure, HbA1c values). In addition, the HIVE lab has developed smartphone-based software that uses AI-enabled cameras to help monitor patients' rehabilitation exercises to ensure that they are doing them in the way their physiotherapists prescribed to aid rapid recovery from operations. Reduced workload and financial pressure The virtual hospital research initiative is leading the way in tackling rising pressure on Ireland's health system, particularly its funding and staffing needs. It will aim to prove a framework that could contribute to lightening the workload of healthcare professionals thereby increasing staff retention while minimising operational costs and optimising the use of healthcare resources. According to the National Insti...

Save 20% on all Nuzest Products WORLDWIDE with the code MIKKIPEDIA at www.nuzest.co.nz, www.nuzest.com.au or www.nuzest.comCurranz Supplement: Use code MIKKIPEDIA to get 20% off your first order - go to www.curranz.co.nz  or www.curranz.co.uk to order yours This week on the podcast Mikki speaks to Dr. Michelle Woolhouse, a  multifaceted physician whose work blends the best of western medical training with the insights of integrative and complementary therapies. Michelle is a general practitioner with qualifications in psychotherapy, acupuncture, hypnotherapy, and integrative medicine. She's also the co-founder of Vively, a platform designed to empower people to take control of their metabolic health through cutting-edge tools like continuous glucose monitoring (CGM).They unpack the journey that brought Michelle to focus on whole-person health. From her early days as a western-trained doctor to the experiences that shaped her understanding of holistic care, Michelle shares powerful insights about how metabolic health underpins not only physical wellness but also mental health, longevity, and quality of life.They discuss the importance of recognising early warning signs of poor metabolic health—long before traditional markers like HbA1c flag a problem. Michelle also explores how lifestyle factors such as stress, sleep, and diet intersect with metabolic health and how her work with Vively is reshaping how people engage with their health through personalised insights and actionable data.If you've ever wondered how technology can bridge the gap between prevention and treatment, or how we might transform mainstream healthcare to prioritise proactive care over reactive care, this episode is for you.Dr. Michelle Woolhouse, an experienced holistic doctor, who integrates the realms of psychotherapy, neuroscience, and integrative functional medicine to guide you on your path to optimal well-being. As the author of "The Wonder Within" and a highly sort after keynote speaker, Dr. Woolhouse offers a transformative approach to healthcare.  Dr. Michelle's specialty differs from the typical medical encounter or standard coaching session, as she dedicates extensive time to each individual, uncovering root cause insights into your unique health journey. Her practice recognises the interconnectedness of mind, body, environment and personal beliefs, guiding you towards holistic wellness and personal empowerment.Drawing on her expertise in psycho-neuro-immunology, nutrition and functional testing, Dr. Woolhouse navigates the intricate language of the brain and body to empower people to better health and outcomes. Through a compassionate approach she supports you in addressing underlying challenges and harnesses the power of mind-body medicine to facilitate personal and professional flourishing.Michelle https://www.drmichellewoolhouse.com/pages/aboutVively app https://www.vively.com.au/  Contact Mikki:https://mikkiwilliden.com/https://www.facebook.com/mikkiwillidennutritionhttps://www.instagram.com/mikkiwilliden/https://linktr.ee/mikkiwilliden

Susan Harris is a television host, reality docuseries guest, former teacher, and encourager. She has reversed Type 2 diabetes, dropping her HbA1c from over 13 to close to 5, using select foods, walking, and a positive mindset, and is passionate about helping others overcome disbetes. Susan has written several books aming them the winning Little Copper Penny series and her memoir Touched By Eternity. Born on the beautiful island of Trinidad, Susan now calls the lush prairies of Saskatchewan home. Susan's family includes her husband, daughter and son-in-law, and the beloved cats. Visit her website at SusanHarris.ca   ✅ Dr Chaffee's website: www.thecarnivorelife.com ✅Join my PATREON for early releases, bonus content, and weekly Zoom meetings! https://www.patreon.com/AnthonyChaffeeMD ✅Sign up for our 30-day carnivore challenge and group here! https://www.howtocarnivore.com/ ✅Stockman Steaks, Australia Discount link for home delivered frozen grass-fed and grass finished pasture raised meat locally sourced here in Australia! Use discount code "CHAFFEE" for free gift with qualifying orders! http://www.stockmansteaks.com.au/chaffee ✅ 60-minute consultation with Dr Chaffee https://calendly.com/anthonychaffeemd/60-minute-consultation   Sponsors and Affiliates: ✅ Brand Ambassador for Stone and Spear tallow and soaps referral link https://www.stoneandspeartallow.com/?ref=gx0gql8b Discount Code "CHAFFEE" for 10% off ✅ Carnivore t-shirts from the Plant Free MD  www.plantfreetees.com ✅THE CARNIVORE BAR: Discount Code "Anthony" for 10% off all orders!   https://the-carnivore-bar.myshopify.com/?sca_ref=1743809.v3IrTuyDIi ✅Schwank Grill (Natural Gas or Propane) https://glnk.io/503n/anthonychaffeemd $150 OFF with Discount Code: ANTHONYMD ✅X3 bar system with discount code "DRCHAFFEE" https://www.kqzyfj.com/click-100676052-13511487 ✅Cerule Stem cells https://DrChaffee.cerule.com ✅CARNIVORE CRISPS: Discount Code "DRCHAFFEEMD" for 10% off all orders! www.carnivorecrisps.com ✅Shop Amazon https://www.amazon.com/shop/anthonychaffeemd?ref=ac_inf_hm_vp   And please like and subscribe to my podcast here and Apple/Google podcasts, as well as my YouTube Channel to get updates on all new content, and please consider giving a 5-star rating as it really helps!   This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast or materials linked from this podcast is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professionals for any such conditions. Music Credit: Music by: bensound.com License code: MPTEUCI8DAXJOKPZ Music: bensound.com License code: FJQPPMCJLHEOYGQB Music: Bensound.com/royalty-free-music License code: KQAKMWSXIH3MJ4WX Music I use: https://www.bensound.com License code: 58NN4QOSKWJ7ASX9   

In this Episode I welcome on Sami Inkinen CEO of Virta Health to discuss Virta Health's approach to Type 2 Diabetes reversal' Virta Health utilizes a continuous remote care intervention (CCI) that incorporates individualized carbohydrate restriction, health coaching, and telemedicine to manage and reverse Type 2 Diabetes We cover topics such as: Impact of individualized carbohydrate restriction: The role of the patient-provider relationship: Addressing quality of food The Virta change model: GLP-1 Receptor agonists as a bridge: Sustainable solutions require addressing nutrition: Research Findings of Virta's approach. Long-Term Effects of CCI: A 2-year non-randomized clinical trial published in Frontiers in Endocrinology showed significant and sustained improvements in multiple clinical markers of diabetes and cardiometabolic health in the CCI group compared to the UC (usual care) group . These included reductions in HbA1c, fasting glucose and insulin, weight, blood pressure, triglycerides, and liver alanine transaminase . The CCI group also saw higher rates of diabetes reversal and remission . GLP-1 Deprescription: A recent study published in Diabetes Therapy explored the impact of discontinuing GLP-1 agonists in patients who had successfully integrated Carb-Restriction Nutrient Therapy (CRNT) supported by Virta's telemedicine model . The study found that patients did not experience weight regain after stopping GLP-1 medications, and while HbA1c levels increased slightly, they generally remained below the diagnostic threshold for diabetes About Sami: Join NowSami InkinenFounder, Chief Executive Officer Sami Inkinen is the Chief Executive Officer and Co-Founder of Virta Health, the leader in diabetes reversal and sustainable weight loss. With a combination of proven nutrition, expert support, and advanced technology, Virta empowers members with the tools and knowledge to sustain changes for a longer, healthier life. A data-driven technology entrepreneur, Sami's personal experience with diabetes and passion to advance global health was the motivation behind Virta. Working with over 500 large employers, health plans, and government organizations across the country, Virta has helped over 100,000 members reverse their diabetes and obesity. Previously, Sami was co-founder of leading online real estate marketplace Trulia, serving as its COO, president, and board member until its IPO and eventual sale to Zillow Group, and held roles at Microsoft and McKinsey & Company. He also founded Fat Chance Row to raise awareness of the dangers of sugar and its connection to diabetes, rowing from California to Hawaii — 2,750 miles — with his wife, completely unsupported.  He holds a MS in engineering physics from the Helsinki University of Technology and a MBA from Stanford University, and is also a triathlon age group world champion and 8 hour 24 minute Ironman finisher, having completed seven Hawaii Ironmans. He lives in Colorado with his wife and two daughters, enjoying the outdoors and the delight of their small barn of egg-laying chickens. Socials Website: https://www.virtahealth.com/Instagram: https://www.instagram.com/virtahealth/?hl=enFacebook: https://www.facebook.com/virtahealth/Linkedin: https://www.linkedin.com/company/virta-healthYouTube: https://www.youtube.com/virtahealthX: https://x.com/virtahealth --- Support this podcast: https://podcasters.spotify.com/pod/show/onethingpod/support

Martha Carlin, a visionary in microbiome research, joins us to unravel the intricate connections between gut health and chronic diseases like Parkinson's and Diabetes. Inspired by her husband's Parkinson's diagnosis, Martha embarked on a groundbreaking quest that led to the founding of BiotiQuest and the development of Sugar Shift. She shares her incredible journey and how her innovative probiotic product demonstrated a remarkable 14% reduction in HbA1c levels over 180 days in a clinical trial in Cuba.Episode Highlights:Discover how gut bacteria influence conditions like diabetes, Parkinson's, and even mood disorders.  Learn about Martha's innovative probiotic, Sugar Shift, designed to reduce sugar cravings, stabilize blood sugar, and support overall gut health.  Martha shares the latest results from her clinical trials, showing the positive effects of Sugar Shift on blood glucose, insulin resistance, and the reduction of harmful endotoxins.  Understand how processed foods, antibiotics, and stress shape our microbiome and what we can do to restore balance.  Martha's mission, inspired by her husband John's battle with Parkinson's, reminds us of the power of commitment in pioneering health solutions. Listen now to uncover the secrets of a healthy microbiome and discover how small changes can lead to powerful results. P.S. Martha has generously offered a special promotion for our listeners: Buy two of her top-rated products, and get the third free! Go here: https://biotiquest.com/pages/kicksugar Start your journey to a healthier microbiome today!Enjoyed this episode? We'd love to hear your thoughts—share your feedback with us here!Florence's courses & coaching programs can be found at:www.FlorenceChristophers.comConnect with Florence on:FACEBOOK | TWITTER | INSTAGRAM | YOUTUBE

Hva trenger vi å måle for å sjekke hva som faktisk virker av alle tiltak vi jobber med, om kosttilskudd tas opp i cellene. Blodprøver er ikke nok, vi må også forstå hvordan celleen nytter seg av næringsstoffene.Vi har med oss Grunder og biohacker Jakob Mørch og lege Arne Løberg Sæther gutta bak Amino.Dette er en digital plattform for folk som vil optimalisere helsen sin, det heter amino.no De ønske rå jobbe med folkehelsen og inspirere til ansvarlig innsats for egen helse ved å tenke preventivt. De deler verktøy via nettstedet som kan hjelpe folk å forstå og analysere det som skjer med helsen.Ideen deres kom på grunn av egen interesse for biohacking og målinger av helsedata. Det å lese data på grafer ble reelt og motiverende for å ta bedre vare på seg selv. Videre ønsket de å følge med på biokjemien og blodverdier som måles på innsiden. Den andre motivasjonen var at Jakob opplevde å ikke få tatt alle de tesene han ønsket å ta hos fastlegen sin. Sammen med Arne klekket de ut plattformen Amino som nå tilbyr et stort utvalg prøver som systematisk følger folk som vil ha oversikt over egne biomarkører. Rett og slett en enklere måte å ta, forstå og samle data på dine egne blodprøver, og deretter omsette informasjonen med gode strategiske råd for å bedre helsen. Alt basert på de siste prøvene dine Vi snakker om flere aspekter:- hvordan er norges helsevesen og tilstand i dag, er det tilrettelagt for preventiv helse eller er det kun sykdomsfokus- hvorfor blir flere syke i dag mht aldersrelaterte og livsstilsrelaterte tilstander - hvordan du kan lære om helse ved å få god feedback på egne biomarkører og plan for å bedre helsen- hva baserer de referansene på når det gjelder blodresultater i forhold til å få best helse- Hvilke anbefalinger bruker AMINO for optimale blodmarkører- Blodprøver viser hva som sirkulerer i blodet på et gitt tidspunkt men ikke nødvendigvis hva som er tatt opp av cellene- Forskjellen på blodplasma verdier og intracellulære prøver og hva de forteller oss- Forskjellen på nivå i blodet og inni cellene og når er det viktig å ta intracellulære prøver- Hvor viktig det er å ha en «baseline» fra du er ung for å se hvordan ting utvikler seg i livet, som egen referanse - Hvordan kan man bruke blodprøvesjekker som tidlig screening for sykdom?- Når blir nivåene skadelige for oss, for eks ved at de er for høye pga kosttilskudd- Hvilke skader kan skje i leveren på grunn av kosttilskudd i lang tid - Hvilke rolle spiller kosttilskudd på blodprøvene- Grønn te ekstrakt, A vit, jern, KAVA, Niacin, anabole steroider som kan skade leveren - Rene versus urene produkter og hvordan skal vi vite hvilke resultater tilskudd kan ha på helse og blodmarkører- Hva er blodtilgjengelighet og hvor stor biotilgjengelighet har for eks: Vitamin C, magnesium, vitamin D i pilleform, - Hvilke pakker tilbyr de og hvilke målinger er i databasen, blod, tungmetaller, CGM osv- Eksempler på ting som pilotkundene av Amino har funnet ut av etter å ha tatt blodprøve?- Målgruppen for plattformen, alt fra biohackere, mannen i gaten til folk som ønsker å bli gravid, til folk med sykdom- Hvordan fremtiden ser ut med flere tester DNA prøver og genetikksammenhenger, CGM,blodtrykk, kobling til smart tech- Hva gjør disse stadige målingene med oss, er det bra eller dårlig?- Hvor mye av kosttilskuddene tas opp i tarmene? Med eller uten mat? Er det generelle regler?- Om magesyren og hvordan mat påvirkes- Ben Greenfield har begynt å drikke juice fordi det skal være bedre nå ref. Siste forskning mht enzymer og magesyre- Hvordan du kan bli kunde på amino.no- Gutta kommer på Biohacking Weekend 5. og 6. april og tester der.Få til slutt med deg våre tips på blodprøver og tester vi biohackere ønsker å ha oversikt på bl.a hormoner, DHEA, kortisol, testo, østrogen skjoldbrusk, metabolisme og vekst, insulin, HBa1c, IGF1, Lipider - CRP, tot kolesterol, næring vitaminer, nyre lever, immunsystem CRP, CBCStor takk til våre sponsorer i episoden:SKINOME HUDPLEIE: Skinome.com Rabattkode: Biohackinggirls20KOLLAGEN: Osloskinlab.no rabattkode: Biohacking70BIOHACKING WEEKEND 2025: https://kongresspartner.no/no/biohacking-weekend-2025

Trong bài viết này, bạn sẽ học được 3 từ khoá mới. Hãy viết xuống và tiếp tục nghiên cứu thêm nhé. 1/ Cảm biến quang-học từ-xa (rPPG) 2/ Chỉ số HbA1c 3/ Hemoglobin ------ Bạn có tin rằng chỉ cần một chiếc điện thoại là có thể đánh giá nhịp tim, huyết áp, và cả chỉ số căng thẳng? Khám phá cùng Linh về công nghệ Transdermal Optical Imaging (TOI) - bí mật đằng sau việc sử dụng camera để theo dõi sức khỏe chỉ trong 30 giây. Linh đã trò chuyện với Vikas Dhar, nhà đồng sáng lập ứng dụng LivWell, để hiểu rõ cách TOI hoạt động và lý do công nghệ này có thể thay đổi cách chúng ta chủ động chăm sóc bản thân mỗi ngày. Trong video, Linh sẽ thử nghiệm so sánh các chỉ số từ LivWell với thiết bị y tế để kiểm chứng độ chính xác! Nếu tò mò về kết quả và muốn biết công nghệ này có thực sự hữu ích, hãy xem hết video nhé.

Join Dr. Emily Cooper, Andrea Taylor, and Mark Wright on Fat Science as they delve into the importance of understanding blood tests for metabolic health. Dr. Cooper provides valuable insights into how these tests can reveal essential details about your metabolism. The episode also highlights the significance of blood markers like A1C, insulin, and hormone levels in maintaining metabolic health. Key Takeaways: Blood tests offer a detailed view into overall health and metabolism, focusing on blood sugar levels, hormones, and cholesterol among other markers. A1C or HbA1C measures average blood sugar over three months, identifying normal range, pre-diabetes, or diabetes. However, it's essential to recognize potential inaccuracies and the necessity of additional markers. Regular testing and using multiple markers are crucial due to the possibility of variations in single tests. The importance of understanding the relationship between glucose and insulin levels is emphasized. Hormone levels like testosterone, estrogen, cortisol, and insulin play a key role in metabolic health and are interconnected with metabolic functions and well-being. Early detection through advanced blood tests, such as fasting insulin and LDL particle analysis, is vital for managing metabolic dysfunction effectively. Personal Stories & Practical Advice: Andrea shares her positive outcomes from discussing expanded test panels with her doctors, resulting in a better understanding of her health. Mark discusses his experience with testosterone therapy and the resulting improvements in energy and mood. Resources from the episode: Connect with Dr. Emily Cooper on LinkedIn. Connect with Andrea Taylor on LinkedIn. Connect with Mark Wright on LinkedIn. Fat Science is a podcast on a mission to explain where our fat really comes from and why it won't go (and stay!) away. In each episode, we share little-known facts and personal experiences to dispel misconceptions, reduce stigma, and instill hope. Fat Science is committed to creating a world where people are empowered with accurate information about metabolism and recognize that fat isn't a failure. This podcast is for informational purposes only and is not intended to replace professional medical advice. If you have a show idea, feedback, or just want to connect, email info@diabesityinstitute.org.

Episode 179: Impact of intermittent fasting Impact on T2DMFuture Dr. Carlisle explains the physiology of fasting and how it can help revert type 2 diabetes. Dr. Arreaza adds details on how to do intermittent fasting. Written by Cameron Carlisle, MSIV, Ross University School of Medicine. Comments and edits by Hector Arreaza, MD, FAAFP.You are listening to Rio Bravo qWeek Podcast, your weekly dose of knowledge brought to you by the Rio Bravo Family Medicine Residency Program from Bakersfield, California, a UCLA-affiliated program sponsored by Clinica Sierra Vista, Let Us Be Your Healthcare Home. This podcast was created for educational purposes only. Visit your primary care provider for additional medical advice.What is type 2 Diabetes Mellitus (T2DM)?-Type 2 Diabetes Mellitus (T2DM) is a metabolic disorder characterized by insulin resistance and impaired glucose regulation. -This impaired regulation can lead to hyperglycemia, contributing to complications in a myriad of organs: heart, kidneys, eyes, nerves, etc. (target organs). According to the CDC, more than 38 million Americans have T2DM (about 1/10 people). -Multiple mechanisms are believed to contribute to insulin resistance in obese patients with T2DM, such as increased lipid deposition throughout the body and systemic inflammation.What is Intermittent Fasting (IF)? Intermittent fasting (IF) has recently gained popularity as a dietary approach for health benefits, but it has been around for thousands of years. IF is an eating pattern that alternates between eating and fasting (no calories consumed) over a specific period of time. When you are fasting, you are allowed and encouraged to keep drinking water and non-caloric drinks, like coffee, tea, and even homemade bone broth.-According to the International Food Information Council Foundation (IFIC), 10% of Americans engage in IF daily. -According to Mark Mattson, a neuroscientist and IF expert for over 25 years, a mechanism called “metabolic switching” is seen with IF. This is when your body runs out of glucose and starts burning fat (i.e., fatty oxidation). These metabolic changes can help protect your organs and reduce the risk of chronic conditions, like T2DM. Common IF methods: Time-restricted eating: Most common method, involves eating within a specific time frame (e.g., the 16:8, 18:6, 12:12 method is also common.  [16:8 means you have 16 hours of fasting and 8 hours of eating.]Alternate-day fasting: Alternating between fasting days and normal eating days.  [Find more info in The Complete Guide to Fasting, by Jason Fung, who is a nephrologist, he explains that alternate-day is basically eating every other day, which would give 36 hours of fasting, but if you are a beginner you can try a 24 hours fasting, in short, not eating breakfast any day of the week and having lunch 4 days a week, and dinner every night.]5:2 diet (aka periodic fasting): Maintaining a normal diet for 5 days, with 2 days (usually non-consecutive) of caloric restriction (25% of normal caloric intake; e.g., 500 calorie meal). IF is strongly believed to improve metabolic health in individuals with T2DM by reducing insulin resistance via increasing insulin sensitivity, promoting weight loss (patients with obesity and DM… AKA patients with diabesity), and enhancing lipolysis via fat oxidation.While fasting, the body goes through several phases that affect how energy is metabolized. Between 0 and 4 hours after eating, the body enters a feeding state, using glucose as its main energy source. After fasting for 12-16 hours, the body enters ketosis and starts to use fat for energy. Within 24-36 hours, autophagy begins, a process that recycles damaged cells and allows for cellular repair. This process can have great benefits for people with T2DM, such as improved insulin sensitivity and glucose regulation. Pathophysiology of Implementing IF in T2DM. -IF is thought to increase insulin sensitivity by decreasing fatty tissue in the body (i.e., visceral adipose tissue), which is correlated to insulin resistance. Insulin resistance is defined as higher than normal circulating insulin levels needed for a glucose lower response, which is thought to be the culprit for the generation of T2DM. It means you need high levels of insulin to keep glucose normal. -Obesity is an important risk factor for T2DM. Visceral adipose tissue functions as an organ via the secretion of adipokines (cytokines or cellular messengers produced by adipose tissue): leptin and adiponectin. Leptin: proinflammatory, leading to chronic inflammation. Patients with higher BMI levels and increased insulin resistance were found to have increased leptin levels.[Leptin is a good hormone at normal levels, but there is leptin resistance] Adiponectin: anti-inflammatory and antidiabetic effects. Higher adiponectin levels result in decreased hepatic gluconeogenesis, enhanced glucose absorption, and enhanced skeletal muscle and hepatic fatty acid oxidation. Levels drop as visceral fat increases. -Dr. López-Jaramillo, a Colombian endocrinologist and researcher, and colleagues published a review in 2014 examining the imbalance in the levels of leptin and adiponectin in individuals with metabolic syndrome. This imbalance (increase in leptin and decrease in adiponectin) is linked to obesity and insulin resistance, which has been shown to increase the risk of T2DM. It has been shown that IF has resulted in the reduction of leptin levels and increased levels of adiponectin, which leads to decreased insulin resistance and increased insulin sensitivity. -IF allows pancreatic beta-cells to rest by not having to secrete insulin constantly. This allows the beta-cells of the pancreas to improve in function over time. In addition, IF has been shown to lead to noticeable weight loss and loss in body fat, both of which play an important contribution in managing T2DM. Research demonstrates that this weight loss increases insulin sensitivity and decreases the need for insulin therapy, making IF a powerful approach for improving metabolic health. AMP-Activated Protein Kinase (AMPK) and Its Role in IF and T2DM Recent research has highlighted an important enzyme seen in IF, AMP-activated protein kinase (AMPK), which plays a vital role as an important energy sensor in cells. It is activated when cellular energy levels are low, such as during IF. A 2020 research study in Nature Reviews Endocrinology explains that activation of AMPK aids in suppressing gluconeogenesis and stimulates fatty acid oxidation, leading to optimal energy balance and reduction of visceral adipose tissue accumulation, a major contributor to insulin resistance and T2DM progression. AMPK is upregulated during fasting, which enhances glucose metabolism and reduces insulin resistance. This is imperative in managing T2DM, as it counters the effects of insulin resistance associated with T2DM.Exercise, which also promotes AMPK activation, complements IF and can promote a synergistic effect in improving insulin sensitivity and promoting fat burning, New Research Findings on IF and T2DM -The EARLY (Exploration of Treatment of Newly Diagnosed Overweight/Obese Type 2 Diabetes Mellitus) study is a randomized clinical trial published in JAMA Network Open (2024). Findings In this randomized clinical trial study found that a time-restricted eating window significantly improved fasting glucose levels and HbA1c levels in individuals with T2DM. The study examined the effect of a 16-week 5:2 meal replacement (5:2 MR) fasting plan that consisted of five days of normal eating and 2 days, nonconsecutive of restricted diet (500-600 calories). This group was examined alongside a group of patients who took metformin 0.5 g BID and empagliflozin 10 mg QD. The study wanted to investigate the changes in HbA1c in Chinese adults with early T2DM.-The study was a randomized clinical trial of 405 adults, and a study showed that the 5:2 MR approach led to better glycemic control at 16 weeks compared to the counter treatments with metformin and empagliflozin. The 5:2 MR group had the greatest reduction in HbA1c (-1.9%), followed by metformin (-1.6%), and empagliflozin (-1.5%). The 5:2 MR plan also revealed the greatest weight loss (-9.7 kg), followed by empagliflozin (-5.8 kg), and metformin (-5.5 kg). -This research suggests IF, such as 5:2 MR, can be a powerful tool in the management of T2DM and improving metabolic health. This study can potentially open doors for healthcare providers to provide the 5:2 MR approach for individuals as an effective initial lifestyle intervention. However, follow-up studies are needed to assess the effectiveness and durability of the 5:2 MR.Safety and Risks of IF in T2DM. -IF when combined with glucose-lowering medications (e.g., insulin, sulfonylureas, GLP-1 agonists) can increase the risk of hypoglycemia. Also, prolonged fasting can lead to nutrient deficiencies if not planned carefully. Patients should be counseled on maintaining a balanced, nutritious diet during non-fasting days. -IF is not suitable for everyone. Children under the age of 18 should not try IF due to needing proper calories for adequate development and proper growth. Also, it is recommended that pregnant or breastfeeding women do not undergo IF. It is advised that people with eating disorders should not try IF. -Individuals with certain medical conditions, such as kidney stones or gastroesophageal disease should speak with their doctor before trying IF. Also, patients on insulin or other glucose-lowering medications should adjust their dose and talk with their healthcare providers to prevent hypoglycemia during fasting. It is recommended that each person speak with their doctor to discuss the safety and risks of IF and see if it would benefit the individual before starting IF. -Many studies have explored the benefits of IF at the micro level revealing its cellular benefits and on a macro level of the body as a whole. However, more research is needed to confirm the long-term effects of IF on glycemic control and its sustainability as a therapeutic approach for T2DM. Conclusion:-IF shows potential for improving glycemic control, promoting weight loss, and enhancing metabolic health in individuals with T2DM. Despite its benefits, IF may present with risks, such as hypoglycemia, nutrition deficiencies, or dehydration in certain patients. Therefore, it may not be suitable for all individuals. It's important to monitor patients who engage in IF, especially for patients with T2DM. Patients should follow up with their doctor for individualized IF plans in patients with T2DM. ______________This week we thank Hector Arreaza and Cameron Carlisle. Audio editing by Adrianne Silva.Even without trying, every night you go to bed a little wiser. Thanks for listening to Rio Bravo qWeek Podcast. We want to hear from you, send us an email at RioBravoqWeek@clinicasierravista.org, or visit our website riobravofmrp.org/qweek. See you next week! _____________________References:Albosta, Michael, and Jesse Bakke. “Intermittent Fasting: Is There a Role in the Treatment of Diabetes? A Review of the Literature and Guide for Primary Care Physicians - Clinical Diabetes and Endocrinology.” BioMed Central, BioMed Central, 3 Feb. 2021, doi.org/10.1186/s40842-020-00116-1.Blumberg, Jack, et al. “Intermittent Fasting: Consider the Risks of Disordered Eating for Your Patient - Clinical Diabetes and Endocrinology.” BioMed Central, BioMed Central, 21 Oct. 2023, https://clindiabetesendo.biomedcentral.com/articles/10.1186/s40842-023-00152-7.De Cabo, Rafael, and Mark P. Mattson. “Effects of intermittent fasting on health, aging, and disease.” New England Journal of Medicine, vol. 381, no. 26, 26 Dec. 2019, pp. 2541–2551, https://doi.org/10.1056/nejmra1905136.Guo, Lixin, et al. “A 5:2 intermittent fasting meal replacement diet and glycemic control for adults with diabetes.” JAMA Network Open, vol. 7, no. 6, 21 June 2024, https://doi.org/10.1001/jamanetworkopen.2024.16786.Herz, Daniel, et al. “Efficacy of Fasting in Type 1 and Type 2 Diabetes Mellitus: A Narrative Review.” Nutrients, U.S. National Library of Medicine, 10 Aug. 2023, www.ncbi.nlm.nih.gov/pmc/articles/PMC10459496/. Herzig, S., & Shaw, R. J. (2018). AMPK: Guardian of metabolism and mitochondrial homeostasis. Nature Reviews Molecular Cell Biology, 19(2), 121-135.Longo, V. D., & Mattson, M. P. (2014). Fasting: Molecular mechanisms and clinical applications. Cell Metabolism, 19(2), 181-192. https://doi.org/10.1016/j.cmet.2013.12.008López-Jaramillo P, Gómez-Arbeláez D, López-López J, et al. The role of leptin/adiponectin ratio in metabolic syndrome and diabetes. Hormone Molecular Biology and Clinical Investigation. 2014;18(1):37–45.Mattson, Mark P., et al. “Impact of intermittent fasting on health and disease processes.” Ageing Research Reviews, vol. 39, Oct. 2017, pp. 46–58, https://doi.org/10.1016/j.arr.2016.10.005. Patikorn, Chanthawat, et al. “Intermittent fasting and obesity-related health outcomes.” JAMA Network Open, vol. 4, no. 12, 17 Dec. 2021, https://doi.org/10.1001/jamanetworkopen.2021.39558.Sharma, Suresh K, et al. “Effect of Intermittent Fasting on Glycaemic Control in Patients with Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.” TouchREVIEWS in Endocrinology, U.S. National Library of Medicine, May 2023, www.ncbi.nlm.nih.gov/pmc/articles/PMC10258621/#:~:text=In%20IF%2C%20eating%20habits%20are,the%20risk%20of%20developing%20T2DM.Xiaoyu, Wen, et al. “The effects of different intermittent fasting regimens in people with type 2 diabetes: A network meta-analysis.” Frontiers in Nutrition, vol. 11, 25 Jan. 2024, https://doi.org/10.3389/fnut.2024.1325894. Theme song, Works All The Time by Dominik Schwarzer, YouTube ID: CUBDNERZU8HXUHBS, purchased from https://www.premiumbeat.com/.

N Engl J Med 2012;367:2375-2384Background: The first large trial to compare PCI vs CABG was SYNTAX. In the subgroup of patients with diabetes, which made up approximately 25% of the trial population, PCI was associated with a higher rate of adverse events compared to CABG, primarily driven by higher rates of repeat revascularization in the PCI group.The Future Revascularization Evaluation in Patients with Diabetes Mellitus: Optimal Management of Multivessel Disease (FREEDOM) trial sought to assess the optimal revascularization strategy for patients with diabetes and multivessel coronary artery disease.Cardiology Trial's Substack is a reader-supported publication. To receive new posts and support our work, consider becoming a free or paid subscriber.Patients: Eligible patients had diabetes and multivessel coronary artery disease defined as a stenosis of 70% or more in two or more major coronary arteries supplying at least two separate territories.Patients with left main stenosis of 50% or more were excluded as well as patients with severe congestive heart failure, prior CABG or valve surgery, stroke within 6 months, significant bleeding within 6 months, 2 or more chronic total occlusions in major coronary territories that are targets for revascularization, and patients with STEMI within 72 hours.Baseline characteristics: The trial randomized 1,900 patients – 953 randomized to PCI and 947 to CABG.The average age of patients was 63 years and 71% were men. The average HbA1c was 7.8 and 32% were using insulin. Approximately 26% had prior myocardial infarction and 16% were current smokers. The average left ventricular ejection fraction was 66%.Approximately 83% had three vessel disease and 6% of the lesions were classified as chronic total occlusions. The SYNTAX score was low (22 or less) in 35% of the patients, intermediate (23 - 32) in 45% and high (33 or more) in 20%.Procedures: Patients were randomized in a 1:1 ratio to undergo CABG or PCI using drug-eluting stents. The use of arterial conduits was encouraged for patients undergoing CABG.Dual antiplatelet therapy with aspirin and clopidogrel was recommended for at least 12 months following PCI.Endpoints: The primary endpoint was a composite of death from any cause, nonfatal myocardial infarction, and nonfatal stroke. Secondary analysis was performed based on the SYNTAX score and study center location; north America vs not.Analysis was performed based on the intention-to-treat principle. The estimated sample size was 1,900 patients to be followed up for at least 2 years. This sample size would provide 80% power to detect a 27% relative risk reduction in one treatment group based on an estimated event rate of 21.5% in the arm with higher event rate.It's important to note that the initial sample size was 2,400 patients but this was amended twice due to slow recruitment.Authors performed 3 interim analyses and therefore, the p value to indicate statistical significance for the primary outcome was adjusted to be 0.044.Results: Among 32,966 patients who were screened for inclusion, 3,309 (10%) were found eligible. Among eligible patients, 1,900 consented to the trial and were randomized. The breakdown for excluding patients was not provided. The median follow up time was 3.8 years (interquartile range: 2.5 - 4.9). In the PCI arm, the average number of lesions stented per patient was 3.5 and 34% underwent a staged procedure. In the CABG arm, the average number of vessels grafted was 2.9 and 94% had a left internal mammary artery graft.At 5-years, the primary outcome was lower in the CABG arm (18.7% vs 26.6%, absolute difference 7.9%, 95% CI: 3.3 – 12.5; p= 0.005). All-cause death was lower with CABG (10.9% vs 16.3%; p= 0.049) as well as myocardial infarction (6.0% vs 13.9%; p< 0.001). When examining the Kaplan-Meier curves for the primary endpoint as well as death (figure 1 of the manuscript), the curves start to diverge, in favor of surgery, at approximately 2-years of follow up.Stroke was higher with CABG (5.2% vs 2.4%; p= 0.03). Excess stroke in the CABG arm was largely within 30-days after the procedure (1.8% vs 0.3%).Major bleeding within 30-days after revascularization was not significantly different between both treatment groups (3.6% with CABG vs 2.4% with PCI; p= 0.13). Acute renal failure requiring dialysis within 30-days after revascularization was higher with CABG (0.8% vs 0.1%; p= 0.02).There were no significant subgroup interactions that included the SYNTAX score, sex, 2- or 3-vessel disease and study center location; north America vs not.Conclusion: In patients with diabetes and multi-vessel stable coronary artery disease, CABG was superior to PCI in reducing the primary endpoint that consisted of death from any cause, nonfatal myocardial infarction, and nonfatal stroke with a number need to treat (NNT) of approximately 13 patients over an average follow-up period of 3.8 years. All-cause death and myocardial infraction were significantly lower with CABG with a NNT of approximately 19 and 13, respectively. Stroke was higher with CABG with a number needed to harm (NNH) of 36 patients. CABG also increased the risk of acute renal failure requiring dialysis within 30-days after revascularization with a NNH of approximately 143.A key difference between this trial and the early CABG trials is the frequent use of internal mammary grafts in FREEDOM (94% vs 10%). Internal mammary grafts are resistant to atherosclerosis and have high patency rates. One possible explanation for the divergent results between this trial and SYNTAX, which also used arterial grafts frequently, is the follow up time. In SYNTAX, patients were followed for 1 year while FREEDOM followed patients up to 5 years and the curves for the primary outcome and death favoring CABG started to diverge at approximately 2 years.When deciding between CABG and PCI for patients meeting the trial's eligibility criteria, it's important to consider the early risks associated with surgery, with the benefits of CABG becoming more apparent after 2 years. Cardiology Trial's Substack is a reader-supported publication. To receive new posts and support our work, consider becoming a free or paid subscriber. Get full access to Cardiology Trial's Substack at cardiologytrials.substack.com/subscribe

In part two of our prediabetes series, hosts Jessica Jones and Wendy Lopez tackle the burning question: How long does it take to reverse prediabetes? We discuss whether it's possible to reverse prediabetes permanently and explore the essential strategies, key milestones, and success factors involved. From food choices and swaps to exercise plans and other lifestyle changes, we break down the steps you can take to manage and potentially reverse prediabetes. Learn about the importance of reduced HbA1c levels, lowered fasting blood glucose levels, and enhanced insulin sensitivity as key indicators of progress. We also highlight the role of working with a dietitian to track goals, milestones, and overall progress!  Our two simple asks to help us continue a free show: Rate on iTunes or Spotify -  it literally takes two seconds Review - if you love the show, please leave a review on iTunes Diabetes & Prediabetes Nutrition Counseling Are you living with diabetes or prediabetes and seeking support from a Registered Dietitian Nutritionist covered by insurance? Visit diabetesdigital.co to sign up for personalized, one-on-one nutrition counseling with one of our culturally aware and weight-inclusive Diabetes Dietitians today!For additional resources and shownotes, visit diabetesdigital.co/podcast

Discover my premium podcast, The Aliquot Learn how to choose the right omega-3 supplement in my free 13-page guide Exercise, meal timing, and sleep are three powerful tools for optimizing metabolic health, a key factor in healthy aging. Even slightly elevated blood glucose levels, but within the "normal" range, can contribute to brain atrophy in areas linked to aging and neurodegeneration. Long-term glucose elevations (high HbA1c) also promote harmful compounds that stiffen blood vessels, reduce heart flexibility, and raise cardiovascular risk. In this episode, recorded at the American Academy of Anti-Aging Medicine conference in Palm Beach, Florida, I provide practical, science-backed protocols on how to implement HIIT, circadian-timed eating, and optimized sleep strategies to dramatically improve metabolic health and protect against these harmful effects.  Timestamps: (00:00) Introduction (04:25) Why HIIT outshines zone 2 for improving metabolic health (06:46) The signaling role of lactate production by muscle (09:33) Optimal HIIT conditions for improving body composition (10:36) How vigorous exercise repairs dysfunctional mitochondria (14:27) HIIT vs. zone 2 for mitochondrial biogenesis (16:09) Evidence-based HIIT protocols (17:46) Why "exercise snacks" are a crucial pre- and post-mealtime activity (19:50) The mortality benefits of short exercise bursts (23:08) Why late-night eating is detrimental (27:37) Can high glucose levels accelerate brain atrophy? (28:30) How circadian misalignment affects postprandial glucose (29:46) Metabolic health benefits of time-restricted eating (32:24) Why early eating is better for metabolic health (34:48) Why losing sleep for 3 nights mimics type 2 diabetes (36:58) Why less than 7 hours of sleep increases type 2 diabetes risk (37:44) Why chronically high blood glucose damages cardiovascular health (39:39) What 4 hours of sleep for 4 nights does to insulin signaling (40:44) Why short sleep facilitates obesity (42:03) The checklist for good sleep hygiene (45:37) Can 1 hour of extra sleep help you lose weight? (46:47) Cognitive behavioral therapy for insomnia (CBT-I) (48:22) How HIIT improves metabolic health when sleep-restricted (50:55) Can HIIT ameliorate the mortality risk from poor sleep? Show notes are available by clicking here Watch this episode on YouTube

Are you finding that your HbA1c levels are elevated despite being on a low-carb, ketogenic, or even carnivore diet? Recently, my HbA1c test came back at 5.7 (just under the prediabetic range), and I knew something was off; after all, I've been following a relatively low-carb lifestyle for years, so there's no way my blood sugar should be high enough to suggest prediabetes.  In consulting with carnivore diet expert and medical doctor Shawn Baker, I learned that healthy red blood cells that live longer than average can actually skew HbA1c readings, making it appear as though you have higher blood glucose than you do. This happens because the longer your red blood cells live, the more glucose has time to attach to hemoglobin, artificially inflating your HbA1c levels. (Conversely, shorter-lived red blood cells can lead to lower readings, even in those with high blood sugar.) In this episode, I break down the science of the HbA1c test and explain how factors like red blood cell lifespan, iron deficiency, anemia, and other health conditions can all affect your hemoglobin A1c results.  Even if you have healthy blood sugar and no signs of diabetes, your HbA1c might still be higher due to these factors. In my case, despite my elevated HbA1c, my continuous glucose monitor (CGM) showed average blood glucose levels between 85 and 89 mg/dL — well within the normal range. In this episode: 00:00:00 - Intro & elevated HBA1C discovery 00:01:15 - Investigating the cause of high HBA1C 00:02:54 - Understanding HBA1C and red blood cells 00:04:19 - Dr. Shawn Baker's explanation: longer lifespan of RBCs 00:06:28 - Conclusion & next episode sneak peek Learn more: Continuous Glucose Monitoring Explained: https://michaelkummer.com/continuous-glucose-monitoring/ Levels vs. Nutrisense: CGM Comparison: https://michaelkummer.com/levels-vs-nutrisense/ Why You Should Wear a Continuous Glucose Monitor (CGM): https://www.primalshiftpodcast.com/44-why-you-should-wear-a-continuous-glucose-monitor-cgm/ How Exercise Influences Your Blood Glucose Response [Coke Challenge]: https://www.youtube.com/watch?v=iIiuRoKtq1s Use the code YOUTUBE10 to get 10% off your order of Grass-Fed Beef Liver supplements at https://shop.michaelkummer.com Affordable At-Home Blood Testing with SiPhox Health: https://www.youtube.com/watch?v=R7qRLzBcp94 Get 20% off your SiPhox Health purchase with the code MICHAELKUMMER at: https://michaelkummer.com/go/siphoxhealth   Ultrahuman vs Oura Ring: What's the BEST Fitness and Sleep Tracker?: https://www.youtube.com/watch?v=E-vAgCh22zk Thank you to this episode's sponsor, OneSkin! OneSkin's lineup of topical skin health products leverage the power of the company's proprietary OS-01 peptide to remove dead skin cells, improve collagen production, increase skin hydration and more. Check out my before and after photos in my OneSkin review and visit OneSkin here. Get 15% off with my discount code MKUMMER: https://michaelkummer.com/go/oneskinshop  Find me on social media for more health and wellness content: Website: https://michaelkummer.com/ YouTube: https://www.youtube.com/@MichaelKummer Instagram: https://www.instagram.com/primalshiftpodcast/ Reddit: https://www.reddit.com/r/michaelkummer/ Pinterest: https://www.pinterest.com/michaelkummer/ Twitter/X: https://twitter.com/mkummer82 Facebook: https://www.facebook.com/realmichaelkummer/ [Medical Disclaimer] The information shared on this video is for educational purposes only, is not a substitute for the advice of medical doctors or registered dietitians (which I am not) and should not be used to prevent, diagnose, or treat any condition. Consult with a physician before starting a fitness regimen, adding supplements to your diet, or making other changes that may affect your medications, treatment plan, or overall health. [Affiliate Disclaimer] I earn affiliate commissions from some of the brands and products I review on this channel. While that doesn't change my editorial integrity, it helps make this channel happen. If you'd like to support me, please use my affiliate links or discount code. #PrimalShift #OptimalHealth #AncestralLiving #Biohacking #HBA1C   

My very special guest, Carnivore Ray, explains how he has been experimenting with his diet by following the carnivore lifestyle for a year. He shares how he has received various reactions and opinions, but ultimately, he believes that experimenting and being open-minded is important for one's health. He also mentions his bloodwork results and how they have improved. Ray is a 26-year-old man who has been following a carnivorous diet for about a year. He initially started this diet as an experiment due to various health issues and was surprised by the positive results. Recently he decided to add fruits to his diet to see if he could still maintain his good health. While he experienced some benefits, he also noticed negative side effects like increased joint pain and inflammation. He first heard about the carnivore diet through a podcast by Joe Rogan featuring Jordan Peterson. He was intrigued by the benefits mentioned by Peterson, including improved mental health and reduced knee pain. He decided to give the diet a try and within the first few days, he experienced weight loss and improved mental acuity. He continued to follow the diet and ended up losing a total of 92 pounds. Most people who criticize the carnivore diet become more open or change their minds after seeing the positive effects on the person following it. Briefly Coach Stephen explains why the HBA1C metric is flawed as it doesn't consider that red blood cells last longer when following a carnivore, keto or low-carb diet. He believes the best indicators of how you're doing is your fasting glucose, insulin, and C-peptide levels. www.linktr.ee/carnivoreray

Modern medicine has long considered many neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease to be immutably linked to the fate of certain unlucky individuals through yet-poorly understood genetic mechanisms. But increasingly, we are seeing evidence that some of our lifestyle choices, including our diet, physical activity, and relationships, may play a significant role in the development of, or protection against, these diseases. Our guest on this episode, David Perlmutter, MD, is a neurologist and writer whose immensely popular books, including Grain Brain: The Surprising Truth About Wheat, Carbs, and Sugar — Your Brain's Silent Killers (2013), discuss why diets low in refined carbohydrates and high in fats, in addition to foods that nurture a healthy gut microbiome, may prevent cognitive decline. Over the course of our conversation, we discuss Dr. Perlmutter's path from conventional neurology to moving towards a more functional and holistic approach to treating brain disorders, the importance of metabolic health in maintaining our cognitive capacities, how Dr. Perlmutter responds to critics of his non-conventional medical advice, why nutrition science is riddled with messy and conflicting findings and how we can better navigate through it all, what clinicians can do to better help their patients live well, and more. Note: Some of Dr. Perlmutter's ideas and recommendations have been the subject of debate and controversy within the medical community. While we believe in fostering open dialog and exploring diverse perspectives, the views expressed in this episode are those of Dr. Perlmutter and do not necessarily reflect the views or endorsements of this podcast. We encourage listeners to critically evaluate the information presented and work with qualified healthcare professionals when making any changes to their health and wellness routines.In this episode, you'll hear about: 3:11 - Dr. Perlmutter's transition from conventional neurology to what he calls “preventative” neurology8:43 - Dr. Perlmutter's views on what constitutes a “disease” and the role of the doctor. 19:08 - Emerging science on the importance of metabolic health on brain health 25:17 - How scientific studies on preventative health can be (and have been) designed 34:56 - Why Dr. Perlmutter prioritizes health markers (such as HbA1c) over specific dietary recommendations when working with patients42:21 - Dr. Perlmutter's views on GLP-1 antagonists such as Ozempic and Mounjaro50:36 - How Dr. Perlmutter has dealt with critics of his workDr. David Perlmutter is the author of eight books. Dr. Perlmutter can be found on Twitter/X at @davidperlmutter. Visit our website www.TheDoctorsArt.com where you can find transcripts of all episodes.If you enjoyed this episode, please subscribe, rate, and review our show, available for free on Spotify, Apple Podcasts, or wherever you get your podcasts. If you know of a doctor, patient, or anyone working in health care who would love to explore meaning in medicine with us on the show, feel free to leave a suggestion in the comments or send an email to info@thedoctorsart.com.Copyright The Doctor's Art Podcast 2024

Cam shares his experience with nutrition from a young age, always being interested in optimizing his health. He tried different diets, including the plant-based approach, but ended up feeling bad and struggling with skin problems and energy. He eventually shifted to a mainly meat-based, low carb diet and started feeling great. In January 2020, he decided to try the carnivore diet and has been sharing his experience and promoting the benefits of animal-based foods. He believes in eating real, whole foods and they also discuss Cam's experimentation with adding fruit and honey back into his diet, and his recent bloodwork that seems to show high cholesterol and slightly elevated HbA1c levels but is not looked at in the context of someone following a carnivore diet. Cam's link https://stan.store/coachcarnivorecam

Send us a textCam shares his experience with nutrition from a young age, always being interested in optimizing his health. He tried different diets, including the plant-based approach, but ended up feeling bad and struggling with skin problems and energy. He eventually shifted to a mainly meat-based, low carb diet and started feeling great. In January 2020, he decided to try the carnivore diet and has been sharing his experience and promoting the benefits of animal-based foods. He believes in eating real, whole foods and they also discuss Cam's experimentation with adding fruit and honey back into his diet, and his recent bloodwork that seems to show high cholesterol and slightly elevated HbA1c levels but is not looked at in the context of someone following a carnivore diet. Cam's linkhttps://stan.store/coachcarnivorecamThank you so much for listening to my podcast. I hope you enjoyed it. Your support means the absolute world to me. And if you're enjoying the show, I've got a small favor to ask you. I'd be incredibly grateful if you would consider becoming a supporter and make a small monthly donation. Your contribution will really help to improve the show. It's a small monthly contribution. You can cancel at any time, and the link is in the show notes. Support the Show.All my links in 1 easy list, including booking and personal training workout plans at LINKTREE You can now download the carnivore experience appApple direct link for apple devices Google play store direct link to app for Android Coach Stephen's Instagram Book me for coaching My growing UK carnivore YouTube channel I have set up a community that is all about eating low-carb and specifically carnivore. CLICK HERE Support my podcast from just £3 per monthBECOME A SUPPORTER Success stories Optimal Health 5 Star reviews All my facebook and other reviews are here Thanks to www.audionautix.com for any music included. Ple...

Learn about important metabolic health concepts surrounding blood sugar control including glycemic variability, insulin resistance, glycemia, diabetes, and blood sugar measures like fasting glucose and HbA1c. We discuss many tips to start improving your blood sugar control without spending money or using medications. If you'd like to show your support with a one-time or monthly donation, please visit: ⁠https://ko-fi.com/nuchihealth ⁠. I'd also like to thank @annabcalligraphy for my artwork this week. Additional resources: Watch previous episodes of The Nuchi Health Podcast mentioned: https://www.youtube.com/playlist?list=PLJc0Lc-M4gGI53qcYKvUFoxkbP0XUuPxu Search terms for at-home test kits: Search at-home blood test kit and look for an option available in your area and that includes the testing outcomes you are interested in (e.g. HbA1c, cholesterol panel). I have previously used Lets Get Checked with positive results. I do not have a financial affiliation with this company. Timestamps: (00:00:18) Episode introduction (00:02:00) Important medical information (00:02:26) Why care about blood sugar? (00:03:40) Definitions: Glucose, types of carbohydrates, glycemia, prediabetes, diabetes, insulin resistance, fasting plasma glucose, and HbA1c (00:08:42) At-home test kits (00:09:59) Healthy, prediabetes, and diabetes blood test measures by FPG and HbA1c (00:11:04) Hemoglobin A1c explanation (00:12:10) Why glucose can be normal while you become insulin resistant (00:13:30) Tips to improve blood sugar control (00:17:02) Glycemic variability (00:22:28) Meal sequencing (when to consume carbohydrates in a meal) (00:25:21) Second meal effect (00:26:58) Circadian rhythm effects on metabolism: eat in fewer hours, stop eating before bed (00:28:35) Closing ABOUT US: Welcome to the Nuchi Health Channel! I'm Dr. Erin Glynn, PhD, and I've studied and researched metabolism, exercise physiology, weight management, and metabolic disease for over 20 years. My YouTube channel and podcast through Nuchi Health are here to provide credible, no-hype health and nutrition information to help people craft their own sustainable, healthy lifestyles for long-term health. We appreciate everyone here with the desire to learn and improve their health! If you find our content valuable, please subscribe and interact with us on your favorite social platform(s): Find us @nuchihealth on: Instagram, Threads, X (Twitter), Facebook, TikTok, and LinkedIn. Please also visit us on our website - www.nuchihealth.com - where you can learn more and sign up for our free monthly newsletter! See our website for important disclaimers regarding use of the information from the Nuchi Health Podcast and our YouTube channel: www.nuchihealth.com/disclaimers and https://nuchihealth.com/terms-and-conditions

Send us a Text Message.My very special guest, Carnivore Ray, explains how he has been experimenting with his diet by following the carnivore lifestyle for a year. He shares how he has received various reactions and opinions, but ultimately, he believes that experimenting and being open-minded is important for one's health. He also mentions his bloodwork results and how they have improved. Ray is a 26-year-old man who has been following a carnivorous diet for about a year. He initially started this diet as an experiment due to various health issues and was surprised by the positive results. Recently he decided to add fruits  to his diet to see if he could still maintain his good health. While he experienced some benefits, he also noticed negative side effects like increased joint pain and inflammation. He first heard about the carnivore diet through a podcast by Joe Rogan featuring Jordan Peterson. He was intrigued by the benefits mentioned by Peterson, including improved mental health and reduced knee pain. He decided to give the diet a try and within the first few days, he experienced weight loss and improved mental acuity. He continued to follow the diet and ended up losing a total of 92 pounds. Most people who criticize the carnivore diet become more open or change their minds after seeing the positive effects on the person following it. Briefly Coach Stephen explains why the HBA1C metric is flawed as it doesn't consider that red blood cells last longer when following a carnivore, keto or low-carb diet. He believes the best indicators of how you're doing is your fasting glucose, insulin, and C-peptide levels.linktr.ee/carnivorerayThank you so much for listening to my podcast. I hope you enjoyed it. Your support means the absolute world to me. And if you're enjoying the show, I've got a small favor to ask you. I'd be incredibly grateful if you would consider becoming a supporter and make a small monthly donation. Your contribution will really help to improve the show. It's a small monthly contribution. You can cancel at any time, and the link is in the show notes. Support the Show.All my links in 1 easy list, including booking and personal training workout plans at LINKTREE You can now download the carnivore experience appApple direct link for apple devices Google play store direct link to app for Android Coach Stephen's Instagram Book me for coaching My growing UK carnivore YouTube channel I have set up a community that is all about eating low-carb and specifically carnivore. CLICK HERE Support my podcast from just £3 per monthBECOME A SUPPORTER Success stories Optimal Health 5 Star reviews All my facebook and other reviews are here Thanks to www.audionautix.com for any music included. Ple...

Why do some people feel fine eating lots of carbs when others feel energy slumps? Is blood sugar to blame? In this episode, we learn why blood sugar varies so much between people, and the tools to manage these levels.  Tim Spector and Jessie Inchauspé (aka the Glucose Goddess) will discuss the latest science around glucose control, what the cool new device on the block – the CGM – can tell us and why blood sugar levels are only one part of the picture of our health. Jessie is a bestselling author and science communicator with a community of over 5 million followers. Tim is a professor of epidemiology at King's College London and ZOE's scientific co-founder.

In this episode of The Luke Coutinho Show, I am excited to bring you an insightful discussion with Dhruv Gupta, an experienced consumer technology entrepreneur and the co-founder of Orange Health Labs. He has a proven track record in developing innovative products and executing successful go-to-market plans.  Join me as we uncover: Inspiration behind Orange Health Labs: Dhruv's personal experience and the need for accurate and reliable medical test results Quality assurance in labs: Health regulations, governing bodies in India like NABL accreditation, and ensuring regular quality control checks Impact of sample collection on lab report accuracy: Significance of pre-analytical factors and reverse logistics SINK tests: The truth about the unethical practice and the need to trust in reputable labs Most common health tests: CBC (Complete Blood Count), HBA1C (for diabetes), thyroid function tests, lipid profiles (heart-related), and kidney and liver function tests (KFT and LFT) Advancements and ethical use of data: Gut microbiome testing, ECG testing at home, and navigating healthcare data privacy  And much more… Chapters: 00:00: Inspiration behind Orange Health Labs 07:47: Quality assurance in labs 13:23: Sample collection and lab report accuracy 17:37: Quality checks within the labs 21:16: Truth about SINK tests 25:01: Most common health tests 30:11: Gut microbiome testing and advancements 36:27: Ethical use of healthcare data 40:24: Key takeaways from Dhruv

What's it like to have an autoimmune disease, resulting in borderline kidney failure and be on the verge of needing a kidney transplant? It must have been really scary to deal with. That's what today's guest Rhonda faced. She had just been diagnosed with an autoimmune disease called IgA nephropathy which significantly impairs kidney function, and in her acute hospitalization, it was found that her Glomerular Filtration Rate (GRF) had already dropped to the super low level of 12. She was about to be put on the transplant list, but she wasn't even 50 years old yet and still had a full life ahead of her, not to mention another grandchild on the way to love.   Yet, following the advice of her kidney doctor, she decided to give plant-based eating a try…and what results she experienced within just 6 months of making this change! Hear about the health transformation Rhonda experienced in part 1 of this Guest Interview. Not only did her kidney function improve naturally, her HbA1c dropped drastically from 8.2 to 5.4, her mental health got better and she went way down in pills. Listen in to learn more of Rhonda's story and be inspired!     ** DON'T MISS IT! 1-YEAR ANNIVERSARY PODCAST DRAWING EVENT ENDS TONIGHT!** To celebrate the milestone of this Podcast reaching the 1-year anniversary mark, I'm giving away a FREE 1:1 Private Coaching Session to a listener. To enter the drawing to win this free private coaching session, do the following 3 steps BEFORE 11:59pm EST on July 23 (TONIGHT), 2024: Leave a 5 star rating and review on Apple Podcasts for this Podcast Take a screenshot image picture of your review Send this screenshot image picture to me at healthnow@plantnourished.com, along with your name and contact email address     Contact -> healthnow@plantnourished.com Learn -> www.plantnourished.com Join -> www.plantnourished.com/ppltcourse Connect in the Facebook Community -> www.bit.ly/pbdietsuccess Apply -> Free Rapid Health Transformation Call: https://bit.ly/plantnourished Free Resource -> Quick Start Grocery Guide for Plant-Based Essentials: www.plantnourished.com/groceryguide     Have a question about plant-based diets that you would like answered on the Plant Based Eating Made Easy Podcast? Send it by email (healthnow@plantnourished.com) or submit it by a voice message here: www.speakpipe.com/plantnourished  

Many enthusiastic climbers work hard to level up their performance year over year, and some of us invest great time, effort, and resources into pursuing our climbing goals. One powerful tool for gaining a performance edge is the use of a functional medicine approach to blood testing…which is the focus of this episode of the T4C podcast. My expert guest joining us for this episode….is Thomas Cunningham, a Louisville Kentucky-based doctor, who also happens to be a 5.14 climber! Dr. Cunningham is a board-certified physician, researcher, and functional medicine specialist who believes in combining evidence-based medicine, nutrition, and training to improve your health, wellness, and human performance. The specific focus of this podcast is the use of regular blood testing, and how you can potentially use blood test results to adjust your nutrition and training in ways that amplify your efforts, accelerate recovery, boost performance, and enhance your overall health and well-being. RUNDOWN 00:15 – T4C podcast mission statement 00:45 – The things we do to level up our performance 1:10 – Intro of podcast topic: Blood testing to optimize health and performance 1:35 – Introducing our expert, Dr. Thomas Cunningham (Instagram: @thomascunninghammd.com) 2:30 – Use of blood test biomarkers 3:45 – Value for older athletes 4:10 – Podcast Sponsor: PhysiVantage Nutrition -- used by 2024 Olympians Natalia Grossman, Alex Megos, and Yannick Flohe'. Get your PhysiVantage at 15% off (code: PODCAST15) at PhysiVantage.com 5:00 – Interview with Dr. Thomas Cunningham 5:30 – What is functional medicine: “Medicine 3.0” 9:30 – Preventative health care through your primary physician – The "Big 4 Killers" 11:20 – Pursuit of “optimal” rather than “average” 14:00 - What testing is appropriate for 20-somethings vs. 50-somethings, etc. 16:40 – “Treat the patient, don't treat the numbers!” 19:15 – Basic blood panels: Metabolic, Lipid, Complete blood count 22:25 – Self-order/self-pay bloodwork at Quest.com or UltaLabs.com 23:30 – More nuanced blood work to consider: Vitamin D, Hormone Panel, Thyroid Panel, HbA1c, ApoB 31:45 – Vitamin supplements to support Testosterone – vitamin D3, zinc, selenium, boron. (PhysiVantage Nutrition VITALIUM is a single-source supplement containing these micronutrients.) 35:00 – The role of genetics, stress, training, nutrition, and sleep. 37:10 – Considerations for vegan athletes. Supplements to consider: B-6, B-12, Iron, D3 + k2, iodine 40:00 – The journey toward optimization. 47:02 – Considerations for female athletes – abnormalities to watch for and treat. 49:50 – Thyroid function and blood panels 53:00 – Hormone changes in women 55:00 – A brief mention of peptides 57:00 – Get the low-hanging fruit…by getting your sleep and nutrition on point…and do some strength training every week. 1:01:00 – Final thoughts Support the TFC podcast sponsor, PhysiVantage Nutrition. Get 15% off full-priced nutrition with checkout code: PODCAST15 (North America only). In Europe and elsewhere visit EPIC-TV Shop or BananaFingers.com to get your PhysiVantage! Music by Misty Murphy SAVE on  La Sportiva shoes here >> Thank you! La Sportiva, Maxim Ropes, DMM Climbing, Friction Labs Follow Eric on Twitter @Train4Climbing Check out Eric's YouTube channel. Follow Eric on Facebook! And on Instagram at: Training4Climbing Copyright 2024 Eric Hörst | Horst Training, LLC.

Make sure to support this podcast by heading over to Paleovalley.com/NwJ and the 15% off discount will automatically be applied to your first order. _____Why do blood sugar, fasting glucose, and A1c (HbA1c) increase on a Carnivore, meat-based diet? (HbA1c is a blood test that measures your average blood sugar level over the past 2-3 months.) I share what and how to check if this is really happening, why it might be happening, and whether it's a concern or not.I discuss the following:Why blood sugar might be higher on a carnivore dietSignificance of A1C and blood glucose measurementsImportance of monitoring insulin and other markersRecommendations for managing blood sugar levels on a carnivore dietUse of continuous glucose monitors for tracking blood sugarPersonal blood sugar and health metrics on a carnivore dietStudies on carnivores and blood sugar levelsRelevance of dolphin studies to human blood sugar levels_____EPISODE RESOURCESComplete Wellness Bloodwork Panel (includes all markers, including NMR Panel, C-Peptide, Fasting insulin and LP-IR)Complete Thyroid Bloodwork PanelCarnivore Diet and the Modern Sugar CrisisCarnivores and High Blood Sugar Studies: https://www.frontiersin.org/journals/endocrinology/articles/10.3389/fendo.2013.00188/full https://www.frontiersin.org/journals/endocrinology/articles/10.3389/fendo.2014.00227/fullhttps://journals.plos.org/plosone/article?id=10.1371/journal.pone.0132117Insulin Resistance: https://diabetesjournals.org/clinical/article/37/3/250/32916/Importance-of-Postprandial-Glucose-in-Relation-tohttps://nutritionandmetabolism.biomedcentral.com/articles/10.1186/1743-7075-2-5_____WEEKLY NEWSLETTER 

Thank you for joining us for our 2nd Cabral HouseCall of the weekend! I'm looking forward to sharing with you some of our community's questions that have come in over the past few weeks…   Nishan: It is extremely rare to find a genuine healer in this day and age. I am still trying to filter through the massive amounts of lies and deception regarding the prostate. Our food and water supply is saturated with chemicals and hormone disruptors. What can I take that will neutralize and eliminate all the crap in my body and rebalance my hormones ? Is there something that will shrink the prostate and crush the multi million dollar industry that's making money off of this illness that is plaguing men ?   Anonymous: I have listened to all your podcasts on both allergies and EBV/viruses. I am in the recovery phase from getting EBV in Dec 2023 (27 yo F, had 104+°F fever for 14+ days). I follow all your protocols and have been trying best to support my recovery. However, the allergens here have been hitting me very severely since getting EBV and causing alot of inflammation. I want to try sublingual allergy drops but want to know your advice for when it would be best to start them in relation to my recovery? Could I start them now, or would it be too much for my immune system to handle? If not, what would be a good indication from my body for when I might be ready to start them? I deeply appreciate all you do for this community   Anonymous: Good morning! Could you please do a podcast going over the differences between cryotherapy vs cold plunges and the unique benefits of each (and who each method might benefit or contraindications)? For example, I notice that cryo makes me feel very relaxed during and afterwards and helps alot with my stress and inflammation - however, cold plunges are a huge stressor on my nervous system and make my stress hormones increase (which I don't feel from cryo). Even though they are both cold therapies, there appear to be differences in how they affect the body, since one provides me benefit whereas the other does not (for me personally). Could you please explain this?   Kimberly: Hello Dr. Cabral, Am I allowed to include black, green and greek olives in my first 21 days? (minus the first 2 liquid diet days of each week) of course. I look forward to beginning my 21 day detox this coming Monday. Thank you, Kimberly   Tin: I am 15 weeks pregnant and I am taking my time to learn more about prenatal and maternity health. I'm curious what are your thoughts about Oral Glucose Tolerance Test? It usually contains 75g of sugar in the solution and taken after fasting. I'm a bit concerned about this much sugar plus the colorings added to that. My OB said this is required to test for gestational diabetes but heard that test can come out false and inaccurate. My FBS and HbA1c are all good, I take supplements and workout, so I think I have low risk. What are other alternatives for this that has less risk to my body? Thank you again for all that you do.   Senna: Hi doctor Cabral, I live in Europe and the European Unition has new rules for retinol usage. They have set a maximum concentration of 0.3% for facial products and 0.05% for body products, in order to mitigate potential health risks associated with excessive retinol exposure. Do you know why they did this, and what these health risks are. I love using my 1% retinol serum and am pretty alarmed by this. Thanks so much for your answer!   Thank you for tuning into this weekend's Cabral HouseCalls and be sure to check back tomorrow for our Mindset & Motivation Monday show to get your week started off right! - - - Show Notes and Resources: StephenCabral.com/3047 - - - Get a FREE Copy of Dr. Cabral's Book: The Rain Barrel Effect - - - Join the Community & Get Your Questions Answered: CabralSupportGroup.com - - - Dr. Cabral's Most Popular At-Home Lab Tests: > Complete Minerals & Metals Test (Test for mineral imbalances & heavy metal toxicity) - - - > Complete Candida, Metabolic & Vitamins Test (Test for 75 biomarkers including yeast & bacterial gut overgrowth, as well as vitamin levels) - - - > Complete Stress, Mood & Metabolism Test (Discover your complete thyroid, adrenal, hormone, vitamin D & insulin levels) - - - > Complete Food Sensitivity Test (Find out your hidden food sensitivities) - - - > Complete Omega-3 & Inflammation Test (Discover your levels of inflammation related to your omega-6 to omega-3 levels) - - - Get Your Question Answered On An Upcoming HouseCall: StephenCabral.com/askcabral - - - Would You Take 30 Seconds To Rate & Review The Cabral Concept? The best way to help me spread our mission of true natural health is to pass on the good word, and I read and appreciate every review!