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This is the nosiest biohack I've ever tried; the IC Hummer from Infopathy administers PEMF infoceuticals sonically and topically to the body for healing, pain relief, inflammation, sleep, vagus nerve modulation, and more! In this [UPDATED] review, I'll break down the PEMF science and tell you about how I've been using it...0:36 Unboxing4:50 Scientific evidence13:30 How I've been using it22:28 Become Boundless with PEMF24:40 IC frequency recommendations26:10 PEMF for brainpower 27:48 Sleep hack30:20 Is PEMF safe?32:50 Criticism: Bluetooth38:46 Update: Dental pain, TSH & Hourglass45:00 About InfopathyFor every mentioned here, read: IC Hummer
Send us Fan MailHave you ever been told your lab work is “normal,” but you still feel exhausted, anxious, foggy, inflamed, or like something just isn't right?You're not imagining it—and you're not alone.In this episode of It's Hertime, Cody sits down with Dr. Jade Guerra, Nurse Practitioner, Doctor of Chiropractic, and Functional Medicine practitioner with nearly 35 years of clinical experience, to explore why so many women continue to struggle despite being told everything looks “fine.”Together they unpack what traditional lab work can miss, why thyroid health is far more complex than a single TSH value, how blood sugar influences everything from hormones to mood, and why healing begins when we stop chasing symptoms and start asking better questions.Whether you're dealing with fatigue, stubborn weight gain, autoimmune disease, thyroid symptoms, brain fog, or simply know your body is trying to tell you something, this conversation will help you understand what's happening beneath the surface.In this episode, you'll learn:Why “normal” lab results don't always mean optimal healthWhy so many women leave medical appointments feeling unheardWhat “root cause” medicine actually meansHow stress changes hormones, metabolism, and thyroid functionWhy TSH is only one piece of evaluating thyroid healthThe connection between thyroid health, gut health, inflammation, and the liverEarly signs of blood sugar dysregulation that often go unnoticedWhy muscle, protein, sleep, and stress all affect insulin sensitivityWhat contributes to autoimmune disease beyond geneticsHow nutrition, movement, nervous system regulation, and targeted supplementation work together to support healingThe simple daily habits that have the biggest long-term impact on healthDr. Guerra also shares her personal journey—from growing up as a first-generation American to building one of the country's largest virtual functional medicine practices—and offers encouragement for women who know they don't feel like themselves but aren't sure where to turn next.If you've ever felt dismissed, discouraged, or frustrated by your health journey, this episode is a reminder that your symptoms deserve curiosity—not dismissal.Connect with Dr. Jade GuerraInstagram: @drjadeguerraWebsite: https://dr.jademalay.com/Special Audience Giveaway:The End Of Type 2 Diabetes NOW! Exposing Myths, Revealing TruthsFacebook Community -132.3K+ Members Unbroken: Women Overcoming Low Thyroid Facebook Community -88K+Members Connect with CodyInstagram: @codyjeansandersWebsite: https://mixhers.com Use Code: Cody for 15% discount⸻If you enjoyed this episode:Subscribe to It's HertimeLeave a review—it helps more women find the show.Share this episode with someone who's been told, “Everything looks normal,” but knows something still isn't right.Did you learn something new today? Be sure to subscribe to this podcast and share this episode with all the girls you love. We would appreciate it if you'd also leave us a rating and review on iTunes.Want to join our Mixhers Girl community and keep this conversation going? We'd love to hear your thoughts, feelings and experiences! Join us HERE!Join Mixhers email list and be the first to have access to new products and be the girl in the know!Follow Cody Instagram:@codyjeansanders
Is it safe to stop statins “cold turkey”? Can the supplement ingredient HMB counteract age-related muscle loss? Researchers may have discovered the key to development of a true fat-burning weight loss medication; Can a mammogram yield clues about cardiovascular risk? Their bottom line threatened by GLP-1 weight loss drugs, BIg Food tweaks portion sizes, adds spices and flavorings to pique blunted appetites; Vitamins A & D may improve lung health for asthma sufferers; When it comes to thyroid medication prescribing, treat the numbers or treat the patient?
The fertilization report looked good. You had eggs. They fertilized. Day three looked fine. Then came the call. Nothing made it past day five, or one did, and it was graded poor, and the cycle was over. You were told it was egg quality, or it was a numbers game, or that you have to try again. Here is what that explanation leaves out. An embryo does not run on one engine the whole way. For the first two to three days it runs almost entirely on the egg, on the proteins, the messenger molecules, and the energy the egg packed during its final growth phase. Then, around the four to eight cell stage on day three, the embryo activates its own genome and takes over, and the paternal contribution comes online. That handover changes where you look. If development stalls in the first three days, you start with the egg and its energy supply. If it looked strong on day three and stalled before the blastocyst, you start with the sperm and its DNA. Same line in the report. Two completely different first moves. Most workups examine neither. They adjust the protocol and go again. In this episode, I walk through the seven factors that shape whether an embryo keeps dividing, and what most clinics never review before they tell you it was your eggs. Pull it up, take notes, and bring it to your next appointment. TIMESTAMPS 00:00 The day five call and what the explanation leaves out 00:55 If this show has helped you, leave a review 01:05 Who reviews your case at Fab Fertile 03:50 Number one: the day three handover and where to look first 06:10 Number two: the egg's energy supply was built before the cycle 08:05 Number three: sperm DNA fragmentation and the standard semen analysis 09:20 Number four: the full thyroid panel, including antibodies 10:20 The Embryo Audit Checklist 10:40 Number five: blood sugar and insulin, for both of you 11:45 Number six: inflammation, the gut microbiome, oxidative stress 12:40 Number seven: the ninety day window and why repeating a cycle repeats the result 13:45 Why the data driven approach works for left brain people 14:30 Chromosomal quality is information, not a verdict 14:55 The Functional Fertility Second Opinion WHAT THE RESEARCH SHOWS A standard semen analysis measures count, motility, and shape. It does not measure the integrity of the DNA inside the sperm. Sperm carrying damaged DNA can still fertilize an egg and produce a normal-looking embryo on day two or three, and development can stall after the genome handover. In a 2025 retrospective analysis of 870 fresh single blastocyst ICSI cycles, each one percent increase in sperm DNA fragmentation was associated with roughly 2.5 percent lower odds of obtaining a top quality blastocyst on day five. The same analysis found that fragmentation was not predictive of clinical pregnancy outcomes. It speaks to why an embryo stalled, not to whether a pregnancy will happen. Thyroid autoantibodies have been detected in follicular fluid at concentrations that correlate with blood levels, which is one reason a complete thyroid panel may include Free T3, Free T4, Reverse T3, TPO antibodies, and thyroglobulin antibodies rather than TSH alone. These are not established diagnostic tests for embryo arrest. They can provide context that a single TSH result cannot. THE EMBRYO AUDIT CHECKLIST If your embryos have arrested and you want to walk through what to review before the next cycle repeats the same result, we built the Embryo Audit Checklist for exactly this. Download it at https://fabfertile.com/pages/embryo-audit-checklist Or email hello@fabfertile.ca, subject line CHECKLIST. FUNCTIONAL FERTILITY SECOND OPINION This is a call where I review your cycle, your labs, your history, and your partner's picture together in one place. You leave knowing what your embryos may be telling you and what the next cycle would be built on, instead of repeating the same outcome. Whatever you decide afterward is yours, but it gets made with information your workup did not give you. Book at https://fabfertile.com/pages/book Or email hello@fabfertile.ca, subject line FERTILE. ABOUT THE HOST I'm Sarah Clark, founder of Fab Fertile and host of Get Pregnant Naturally, a podcast with over one million downloads. My functional fertility team works with couples navigating low AMH and failed IVF, reviewing functional lab results, gut microbiome, food sensitivity, vaginal microbiome, nutrigenomics, HTMA, DUTCH, toxin testing, and bloodwork alongside nervous system work, to help identify patterns that may not have been considered. We work alongside your medical team, not instead of them. Subscribe to Get Pregnant Naturally for weekly episodes on fertility optimization, IVF preparation, and the lab work your doctor probably isn't running. Sarah Clark, founder of Fab Fertile, host of Get Pregnant Naturally (1M+ downloads), and author of Fabulously Fertile. If this episode helped you make sense of your own numbers, leave a review wherever you listen. It is how another woman, being told the same thing, finds her way here. REFERENCES Machałowski T, Machałowska J, Gill K, et al. Sperm DNA Fragmentation Impairs Early Embryo Development but Is Not Predictive of Pregnancy Outcomes: Insights from 870 ICSI Cycles. International Journal of Molecular Sciences. 2025. doi:10.3390/ijms26167923 Monteleone P, Parrini D, Faviana P, et al. Female infertility related to thyroid autoimmunity: the ovarian follicle hypothesis. American Journal of Reproductive Immunology. 2011. American Urological Association and American Society for Reproductive Medicine. Diagnosis and Treatment of Infertility in Men: AUA/ASRM Guideline. 2020.
I am honored to have Dr. Carrie Jones back on the podcast today. She's a naturopathic physician and hormone expert with over 20 years of clinical experience in women's health and endocrinology. In today's conversation, we unpack common social media myths about midlife, the influence of lifestyle choices in perimenopause, the role of cortisol and hormones, and current research on the parasympathetic nervous system. Dr. Jones explains vagal freeze, how our stress response can exacerbate it, and why stress has become so normalized. We also explore the influence of synthetic hormones, thyroid propaganda, immune system function, autoimmunity, lab reference values and ranges, and the timing hypothesis of hormone replacement therapy, and Dr. Jones shares her favorite new supplements. Stay tuned for another insightful conversation with one of my favorite voices in the hormone space. IN THIS EPISODE, YOU WILL LEARN: The importance of being thoughtful about information shared on social media regarding perimenopause and menopause How chronic stress becomes harder to tolerate and can cause an increase in inflammation during perimenopause Some simple strategies to help you feel safe, connected, and supported, and improve your vagal tone How actual stress, anticipated stress, and perceived stress all activate the same stress response How chronic stress affects every system within the body How certain women can tolerate synthetic hormones very well, while others develop various symptoms Why basic blood tests and reference ranges are not always optimal for everyone Factors that could influence thyroid function, and the benefits of a broader thyroid assessment than TSH alone Dr. Jones explains why she prefers to start hormone therapy early in perimenopause if appropriate The new supplements Dr. Jones uses to support mood, stress, and sleep Connect with Cynthia Thurlow Follow on X, Instagram & LinkedIn Check out Cynthia's website. Submit your questions to support@cynthiathurlow.com Join other like-minded women in a supportive, nurturing community: The Midlife Pause/Cynthia Thurlow. Purchase Cynthia's book, The Menopause Gut. Cynthia's Intermittent Fasting Transformation Book The Midlife Pause Supplement Line Connect with Dr. Carrie Jones On her website Instagram YouTube Hello Hormones Podcast
What Your TSH Number Isn't Telling You ft. Dr. Brittany Henderson Your TSH can look "perfectly normal" and you can still feel exhausted, foggy, cold, and stuck at a weight that won't budge. In this episode of the Medical Disruptor, I sit down with thyroid specialist Dr. Brittany Henderson to find out why. Dr. Henderson is fellowship-trained at Duke, ran thyroid programs at two major academic centers, and now runs her own thyroid-only practice, the Charleston Thyroid Center. She told me flat out that TSH alone is not enough, and that most doctors don't even know how to read a full thyroid panel. In this conversation we get into why TSH is actually a pituitary hormone, not a thyroid hormone, and why the "normal" TSH reference range was built on flawed population data that included undiagnosed Hashimoto's patients. I ask her what free T4, free T3, and reverse T3 actually reveal that TSH can't, and she walks me through why muscle mass is the missing piece in thyroid hormone conversion, since it's muscle tissue that activates T4 into usable T3. She also explains why up to 95% of people with severe Hashimoto's or a thyroidectomy may need combination T4/T3 therapy instead of T4 alone, and we break down the real differences between levothyroxine, desiccated thyroid extract, and combination treatment. We talk about patients who've been on the wrong thyroid medication for decades and what happens when it's finally corrected, plus the flip side: patients who never needed thyroid medication in the first place and how to tell the difference. Along the way we cover how birth control, inflammation, steroids, and menopause quietly throw off your thyroid labs without anyone telling you. If you've ever been told your thyroid is fine while your body is telling you otherwise, this episode gives you the exact labs to ask for and the language to ask for them. Want more practical health tips? Join my newsletter! https://freechapter.lpages.co/newsletter-opt-in/ Still second guessing yourself in the exam room? Click here! https://freechapter.lpages.co/self-gaslighting-habits-to-watch-for/ Check us out on social media: https://www.instagram.com/drefratlamandre https://www.facebook.com/drefratlamandre https://www.tiktok.com/@drefratlamandre #functionalmedicine #drefratlamandre #medicaldisruptor #NPwithaPHD #nursepractitioner #medicalgaslighting Chapters 0:00 - Introduction 2:10 - From Duke-Trained Endocrinologist to Questioning the Standard of Care 12:38 - Why TSH Alone Is Not Enough 23:16 - Combination Therapy and the Muscle Mass Connection 25:17 - Desiccated Thyroid Extract: History and Misconceptions 35:19 - Pushback, Broken Guidelines, and Where to Find Dr. Henderson Guest Links: FB: https://www.facebook.com/DrHendersonMD/ IG: https://www.instagram.com/mythyroiddoctor/ Website:charlestonthyroidcenter.com | mythyroiddoctor.com | thethyroidfoundation.org Learn more about your ad choices. Visit megaphone.fm/adchoices
Welcome to this week's Midlife Minute. In this episode, we're focusing on progesterone, exploring the differences between progesterone and progestins, how progesterone is used in clinical practice, and how individual responses can vary significantly. IN THIS EPISODE, YOU WILL LEARN: Why bioidentical progesterone and synthetic progestins are not interchangeable How early synthetic progestin studies continue to shape how progesterone is viewed How different routes of progesterone administration produce different effects Why do some women experience stronger neurological or physical effects than others on the same progesterone dose How cyclical versus continuous use can affect how progesterone is used in the body Why some women experience sleep or mood changes on oral progesterone The importance of personalized decision-making Connect with Cynthia Thurlow Follow on X, Instagram & LinkedIn Check out Cynthia's website. Submit your questions to support@cynthiathurlow.com Join other like-minded women in a supportive, nurturing community: The Midlife Pause/Cynthia Thurlow. Purchase Cynthia's book, The Menopause Gut. Cynthia's Intermittent Fasting Transformation Book The Midlife Pause Supplement Line Resources: The pharmacodynamics and safety of progesterone doi:10.1016/j.bpobgyn.2020.06.002 Profiles of plasma estrogens, progesterone and their metabolites after oral or vaginal administration of estradiol or progesterone doi:10.1016/0378-5122(93)90064-O Pharmacokinetics of progesterone and its metabolites allopregnanolone and pregnanolone after oral administration of low-dose progesterone doi:10.1016/j.maturitas.2005.11.005 Allopregnanolone and mood in the peripartum: a longitudinal assessment in healthy women doi:10.1016/j.psyneuen.2019.104465 Behavior of Male Gamete Fusogen GCS1/HAP2 and the Regulation in Arabidopsis Double Fertilization doi:10.3390/biom13020208 Tolerance to allopregnanolone with focus on the GABA receptor doi:10.1111/j.1476-5381.2010.01059.x Effects of exercise training on the cardiovascular system: pharmacological approaches doi:10.1016/j.pharmthera.2007.03.010 Sex steroid induced negative mood may be explained by the paradoxical effect mediated by GABA modulators doi:10.1016/j.psyneuen.2009.02.003 Paradoxical effects of GABA modulators may explain sex steroid induced negative mood symptoms in some persons doi:10.1016/j.neuroscience.2011.03.061 Progesterone selectively increases amygdala reactivity in women doi:10.1038/sj.mp.4002030 Progesterone and allopregnanolone neuroprotective effects in the central nervous system doi:10.1016/S0006-8993(02)02366-5 Allopregnanolone and mood disorders doi:10.1016/j.pneurobio.2013.07.005 GABA receptor plasticity and neurosteroid cell withdrawal during the estrous cycle doi:10.1523/JNEUROSCI.2800-09.2009 Unequal risks for breast cancer associated with different hormone replacement therapies: results from the E3N cohort study doi:10.1007/s10549-007-9523-x Management of Menopausal Symptoms: A Review doi:10.1001/jama.2022.24140 Progesterone vs. synthetic progestins and the risk of breast cancer: a systematic review and meta-analysis doi:10.1080/13697137.2018.1467611 Progesterone prevents sleep disturbances and modulates GH, TSH, and melatonin secretion in postmenopausal women doi:10.1210/jc.2010-2558
In this episode, Dr. Amie Hornaman, the “Thyroid Whisperer” and author of The Thyroid Fix, breaks down the complexities of thyroid health, explaining why millions of people continue to struggle with symptoms despite being told their thyroid is "normal." She explores the key differences between hypothyroidism and hyperthyroidism, with a special focus on Hashimoto's disease, the autoimmune condition responsible for the vast majority of hypothyroidism cases. Dr. Hornaman explains why comprehensive thyroid testing goes far beyond measuring TSH alone. She discusses the importance of evaluating Free T3, Free T4, Reverse T3, and thyroid antibodies to uncover hidden thyroid dysfunction that standard lab work often misses. The conversation also highlights why many patients continue to experience fatigue, brain fog, weight gain, hair loss, depression, and low energy even after beginning traditional thyroid treatment. The episode examines the relationship between thyroid dysfunction and perimenopause, menopause, and hormonal changes, emphasizing how thyroid disorders are frequently overlooked in women during midlife. Dr. Hornaman also discusses how an underactive thyroid can reduce the effectiveness of GLP-1 weight loss medications, making proper thyroid optimization essential for successful weight management. Listeners will learn when lifestyle changes, nutrition, and targeted supplementation may help support early thyroid dysfunction, as well as when thyroid hormone replacement therapy becomes necessary. Dr. Hornaman explains why thyroid hormone replacement is generally a lifelong treatment once significant thyroid damage has occurred, distinguishing it from other forms of hormone replacement therapy. Whether you're experiencing unexplained symptoms, have been diagnosed with Hashimoto's thyroiditis, hypothyroidism, or are seeking better answers about hormone health, this episode provides practical, evidence-informed insights into diagnosis, treatment options, and long-term thyroid wellness. The Thyroid Fix: Book Link Show Notes/Links: www.hotflashescooltopics.com PLEASE RATE AND REVIEW AND SHARE! Instagram: https://www.instagram.com/hotflashesandcooltopics YouTube: https://www.youtube.com/@HotFlashesCoolTopics TikTok: @hotflashescooltopics2
In this empowering episode, Dr. Fiona Lovely welcomes nurse practitioner Shelby Sheppard, a trusted hormone and sexual health expert who has been caring for Dr. Lovely's own patients for years. Shelby's journey from labor and delivery RN to founding Pause Health reflects her deep commitment to offering women the time, space, and personalized care they deserve—something that simply cannot happen in the standard medical seven-minute appointment. The conversation opens with the remarkable story of how Shelby helped a patient navigate postpartum depression using supplemental progesterone, challenging conventional medical dogma. They then dive into the blind spots of thyroid care, explaining why TSH alone is an unreliable marker and why T4-only medications often leave women feeling unwell. Shelby shares her philosophy of offering patients a menu of options rather than a one-size-fits-all approach. They explore the newly renamed PMOS (Polyendocrine Metabolic Ovarian Syndrome) from PCOS, the underutilized role of testosterone in women's health, and the profound impact of GLP-1 medications on metabolic health and mental well-being. The episode also addresses sexual health, pleasure anatomy, and why women deserve to feel plugged back in—not just for sex, but for life. Together, they talk about: Why progesterone can be a game-changer for postpartum mood support as well as perimenopausal sleep disturbances, anxiety and others. The limitations of TSH testing for thyroid and why free T3 and reverse T3 matter. How GLP-1s combined with hormone therapy offer superior metabolic results. Testosterone's role in motivation, confidence, and overall vitality. Practical tips for navigating libido changes and communicating with partners. Tune in to learn why women's health is not a one-size-fits-all prescription—and how to become your own best advocate. Connect with Shelby: Website: www.pausehealth.ca Instagram: https://www.instagram.com/pause_health Thank you to our sponsors for this episode:
Estrogen is the hormone women are told to fear, and never told it is actually the one they need most. In this episode of The Medical Disruptor, I sit down with endocrinologist Dr. Cassie Smith to dismantle the hormone myth that's kept millions of women suffering: the belief that estrogen and hormone therapy cause cancer. Dr. Cassie trained at one of the top metabolism and endocrinology fellowships in the country, was named chief resident, ran clinical trials, and then walked away from conventional medicine because the system was failing her patients, and failing her. What she's seen treating thousands of women tells a very different story than what your doctor was taught. We get into why "normal" thyroid labs don't mean you're healthy, how your gut secretly controls whether your hormones actually work, why TSH is a terrible standalone test, and why hormones done correctly can extend longevity and lower your risk of heart disease, dementia, and disease, not raise it. If you've been hesitant about hormone therapy, this conversation will give you the context you need, so you can make a decision based on how hormones truly work, not on outdated fear. Want more practical health tips? Join my newsletter! https://freechapter.lpages.co/newsletter-opt-in/ Stop getting dismissed at the doctor's office.Get Dr. E's FREE 5 Red Flag Phrases guide here: https://freechapter.lpages.co/5-phrases-that-are-red-flags/ Check us out on social media: https://www.instagram.com/drefratlamandre https://www.facebook.com/drefratlamandre https://www.tiktok.com/@drefratlamandre #functionalmedicine #drefratlamandre #medicaldisruptor #NPwithaPHD #nursepractitioner #medicalgaslighting Chapters 0:00 - Introduction 4:38 - A Doctor Diagnosed, Dismissed, and Gaslit 11:10 - How Your Gut Controls Your Hormones 19:52 - Why "Normal" Labs Don't Mean You're Healthy 26:13 - What to Ask Your Doctor (and When to Leave) 34:58 - The Truth About Hormones and Cancer Guest Links: FB: https://www.facebook.com/ModernEndocrine IG: https://www.instagram.com/modernendocrine_/ YT: https://www.youtube.com/@modernendocrine Website: https://www.modern-endocrine.com/ Learn more about your ad choices. Visit megaphone.fm/adchoices
In this episode, I dig into one of the most frustrating things I see women struggle with: being told their thyroid is "fine" based on a single number, while they're still dealing with fatigue, weight gain, hair thinning, brain fog, and feeling cold all the time. Here's what I want you to take away: TSH isn't a full thyroid test. It's just a signal from your brain to your thyroid—not a measurement of what your body is actually producing or whether your cells can use it. The "normal" range is so wide you could drive a Mack truck through it. Normal doesn't mean optimal. The numbers I actually look at: Free T3 – the active hormone your cells actually use. It's the one that matters most and almost never gets tested. You can have plenty of T4 (the storage form) and still feel awful if you're not converting it. Reverse T3 – I think of this as the brake pedal that stress slams on. It's a mirror-image molecule (like your left hand vs. your right) that parks in your receptors and blocks the active hormone from getting in. Chronic stress, low iron, illness, crash dieting, and inflammation all push your body to make more of it. TPO and TG antibodies – these can rise 7 to 10 years before your TSH ever moves. Catching Hashimoto's early gives you a window to address the root drivers. It's never just one thing. Your thyroid gets ambushed—inflammation, stress, nutrient deficiencies, gut issues—all stacked and compounded over time. This is especially true in perimenopause, when rising cortisol, falling ferritin from heavy periods, and lower stomach acid all converge. That's why so many women hit a thyroid crash in their 40s. A real story from my own life: I went in for a checkup and asked to have my antibodies retested (I have a history of Hashimoto's). My doctor physically couldn't add the lab to my file because the system only allows it once—even though my previous result was out of range. This isn't about one bad doctor; the system isn't built to support you. I now have to order my own labs through an outside lab. What your body needs to convert T4 to T3: selenium, zinc, iron, and a calm nervous system. These nutrients are commonly depleted in women, especially with a history of oral birth control. And food is the most bioavailable source—so variety matters. Eating the same meal-prepped chicken and broccoli every week can leave you deficient. A word on supplements: more isn't better. I recently had to remove several supplements from a client's routine because they were overloading her with B vitamins and depleting her minerals. Expensive and fancy doesn't mean right for your body. My bottom line: You have to be the driver of your own health. Look back through your old labs right now and check whether your antibodies and Free T3 have ever been tested. If you've been struggling for six months or more, take action. Your body has an incredible ability to heal when we test properly, look at the whole picture, and give it the right things at the right time. If you need help figuring out your next steps, the link to schedule a strategy call with my team is in the show notes. You're not too far gone—you're closer now than you were before you knew this!
Low AMH, failed IVF, or told donor eggs, and still no real explanation for why? This episode looks at the system a standard fertility workup rarely checks: the nervous system, and how chronic stress affects egg quality, progesterone, thyroid function, and ovulation. If you are a high-achieving, Type A woman who has been told your stress is handled and your thyroid is fine, this is the seven things behind low AMH, diminished ovarian reserve, and recurrent pregnancy loss that rarely get investigated, including the cortisol pattern, the full thyroid panel, blood sugar, prolactin, and the stress nerves that run directly through the ovary. This episode covers: low AMH and high FSH, the cortisol curve, a single blood draw misses, thyroid antibodies and reverse T3 behind a "normal" TSH, how stress pulls raw material away from progesterone, blood sugar, and the 3 am wake-up, elevated prolactin, and the nervous system inside the ovary affecting egg quality. This episode is for you if you have low AMH, diminished ovarian reserve, a failed or cancelled IVF cycle, or recurrent miscarriage, and you have been told donor eggs are your only option, and no one has explained why this is happening. CHAPTERS 00:00 Why the woman who handles everything is the one who needs this 03:00 The seven things, and why this is physiology, not mindset 03:40 One: survival first, and reproduction turned down 05:00 Two: why a single cortisol draw misses the pattern 06:00 Three: thyroid antibodies and reverse T3 behind a normal TSH 06:50 Four: how stress competes with progesterone 07:50 Five: the 3am wake-up is blood sugar, not anxiety 09:00 Six: the prolactin that got flagged, then dropped 09:30 Seven: the nervous system inside the ovary 11:00 What you can actually change 12:30 The Functional Fertility Second Opinion NEXT STEPS What Your Clinic Missed guide: the lab markers behind each of the seven, in writing. Email hello@fabfertile.ca, subject MISSED. Functional Fertility Second Opinion: a call where I review your full picture, your labs, your blood sugar, and your partner's results, and help you make an informed next decision. Email hello@fabfertile.ca, subject FERTILE, or book a call with your partner here. I'm Sarah Clark, founder of Fab Fertile and host of Get Pregnant Naturally, a podcast with over one million downloads. My functional fertility team works with couples navigating low AMH and failed IVF, reviewing functional lab results, gut microbiome, food sensitivity, vaginal microbiome, nutrigenomics, HTMA, DUTCH, toxin testing, and bloodwork alongside nervous system work, to help identify patterns that may not have been considered. We work alongside your medical team, not instead of them. Subscribe to Get Pregnant Naturally for weekly episodes on fertility optimization, IVF preparation, and the lab work your doctor probably isn't running. Get Pregnant Naturally: A Functional Fertility Second Opinion. If this show has helped you make sense of your numbers, please leave a review. It helps other women find the show and be their own advocate.
You've made it to part three, and this is the one that ties everything together. If parts one and two left you with a clearer picture of your stress system and your sleep, this episode takes you somewhere deeper: into your thyroid, your brain chemistry, and a layer of midlife that almost nobody talks about on a podcast about hormones. I'm breaking down why your thyroid and your adrenal system are locked in a relationship that most doctors never explain, and why a normal TSH does not mean your thyroid is actually working. Then we go into your neurotransmitters. Serotonin, dopamine, GABA, the gut connection. If you've ever wondered why you suddenly feel less resilient, less motivated, or like you don't know who you are anymore, this is the missing piece. And if you've been prescribed an antidepressant during perimenopause or menopause, I want you to hear this part especially. But this episode also goes somewhere I don't always go. We talk about the identity and spiritual layer of this transition. The old patterns, the buried feelings, the relationships and jobs that suddenly feel impossible to keep tolerating. I share something personal about what came up for me last year, and why I believe what feels like falling apart in midlife might actually be something else entirely. And because I know all of this can feel like a lot, I close the series with exactly where I'd start if I were you. What to test, what to ask for, and what I actually do every night for my own sleep. In This Episode, We Cover: Why a normal TSH result does not mean your thyroid is functioning properly The two way relationship between chronic stress, cortisol, and thyroid hormone conversion Why so many women are prescribed antidepressants in perimenopause and menopause when the real driver may be hormonal How estradiol affects serotonin (your sense of okay-ness) and dopamine (your motivation and drive) The role of progesterone and GABA in anxiety, racing thoughts, and the 2 to 4 AM wake up How chronic cortisol elevation disrupts neurotransmitter balance across the board Why 90 percent of your serotonin is made in your gut, not your brain The spiritual and identity layer of perimenopause and menopause, and why old patterns resurface now A personal story about a repeating pattern Karen had to finally face What Karen recommends first: the four point cortisol and DHEA test, and why it matters more than a single blood draw Karen's actual nightly routine for sleep, including HRT and magnesium Who This Episode Is For This one is for you if you have been told your labs are normal but you do not feel normal. It's for the woman who has been on an antidepressant for years and has quietly wondered if her hormones were ever part of the conversation. It's for anyone who feels more anxious, less motivated, or less like themselves than they used to, and cannot figure out why. And it's for the woman who feels like midlife is cracking something open in her, whether that shows up as a relationship that no longer fits, a job that drains her, or a feeling she cannot quite name yet. Sponsors Timeline is offering up to 39% off your first order of Mitopure. Gummies. Go to timeline.com/HORMONE use coupon HORMONE Get 15% off Masszymes By BiOptimzers at bioptimizers.com/hormone with coupon code HORMONE. Are you in perimenopause or postmenopause and struggling with symptoms—but not getting the support you deserve? At Midlife Solutions, we specialize in hormone optimization for women in midlife. Our all-female clinical team offers telehealth care across all 50 U.S. states, with the ability to prescribe bioidentical estrogen, progesterone, testosterone, and thyroid medication. Book your FREE Hormone Discovery Call Find out what's really driving your symptoms and what your next best steps are. Visit the website: https://karenmartel.com Shop the Midlife Solutions Store Over-the-counter bioidentical hormone creams and oils — no prescription needed. Including: • Progesterone • Estrogen Face Cream • Vaginal Moisturizer and more! Take the Hormone Quiz Discover hidden hormone imbalances that could be driving your symptoms. Get personalized results (and yes, they may surprise you). Women's Peptide Weight Loss Program Clinically guided, hormone-aware weight loss for midlife women. Midlife RESET HRT Program A complete, supportive approach to hormone replacement therapy in midlife. Your host: Karen Martel Certified Hormone Specialist, Transformational Nutrition Coach, & Weight Loss Expert Karen's Facebook Karen's Instagram
Można Pięknie Żyć *---Witaj! "Można Pięknie Żyć*" to seria podcastów, w której odkrywamy, jak zmiany w stylu życia mogą poprawić nasze zdrowie metaboliczne. Skupiamy się na Terapeutycznym Ograniczaniu Węglowodanów i jego pozytywnym wpływie na metabolizm oraz ogólne samopoczucie. Pamiętaj, że zdrowie zaczyna się od wiedzy, a my jesteśmy tu, aby dostarczać Ci inspirację i praktyczne wskazówki na drodze do pięknego życia. Zaczynamy! W tym odcinku ujawniamy kulisy powstawania norm laboratoryjnych i tłumaczymy również, dlaczego wynik mieszczący się „w normie” wcale nie musi oznaczać, że jesteśmy zdrowi. Wyjaśniamy różnicę pomiędzy czysto statystyczną wartością referencyjną a wartością optymalną dla ludzkiego organizmu, ostrzegając przed ukrytymi chorobami metabolicznymi. W tym odcinku dowiesz się:Skąd wzięły się normy laboratoryjne – Poznasz historię biochemii od analizy smaku moczu, przez rewolucyjny autoanalizator Leonarda Skeggsa z 1957 roku, aż po oficjalne rekomendacje.Kulisy obniżania norm – O tym, jak decyzje amerykańskich towarzystw diabetologicznych z lat 1997–2010 z dnia na dzień zamieniły miliony zdrowych ludzi w pacjentów i jak powiązane było to z finansowaniem ekspertów przez firmy farmaceutyczne.3 kluczowe badania, które musisz wykonaćNa koniec odcinka przypominamy, że oficjalny konsensus medyczny pozwala na pełne odwrócenie i remisję cukrzycy typu drugiego.
Ever been mid-sentence and the exact word you need just completely vanishes? If you are in perimenopause, you've likely experienced this deeply disorienting form of brain fog. But despite what you may have been told, you are not losing your mind, and it is not "just stress." In this episode, we break down the real clinical explanations behind perimenopausal cognitive changes. We look at how fluctuating hormones affect your brain, why standard labs often miss the full picture, and how to have a more useful conversation with your doctor so you can get your sharpness back. In This Episode, You Will Learn: How shifting estrogen levels directly impact the parts of your brain responsible for memory, focus, and word retrieval. Why hormones spike and drop erratically during this transition, making a single, standard blood draw mostly useless. Why a "normal" standard thyroid test (TSH) doesn't guarantee your brain cells are actually getting the energy they need. How low iron stores mimic brain fog, and why "not anemic" is not the same thing as having enough iron for optimal brain function. The exact tests to ask for at your next appointment including a full thyroid panel, ferritin, Vitamin D, and B12 to get real answers. Take the Why Am I So Tired assessment at whyamisotired.hopenaturalhealth.com For more on Dr. Erin: Join The Hope Circle Community: https://hormonehealingproject.drerinellis.com/communities/groups/the-hope-circle/home?invite=69120d498b7e3f60397656b8 Work with Dr. Erin here: https://p.bttr.to/3E88ps4 Buy Dr. Erin's Supplements here: https://drerinellis.com/shop Get the Period Productivity Planner here: https://www.amazon.com/dp/B0BBYBRT5Q?ref_=pe_3052080_397514860 Download the FREE Menstrual Cycle Nutrition Guide here: https://detox.drerinellis.com/ Watch The Free Video "7 Hormones Affecting Your Weight Loss Goals" here: https://weightloss.drerinellis.com/ Let's Be Friends: Follow Dr. Erin on Instagram: https://www.instagram.com/dr.erinellis/ Follow Dr. Erin on Facebook: https://www.facebook.com/drerinellisnmd Follow Dr. Erin on TikTok: https://www.tiktok.com/@dr.erinellis?lang=en Join the Free Hope Circle Community: https://hormonehealingproject.drerinellis.com/communities/groups/the-hope-circle/home?invite=69120d498b7e3f60397656b8 Bookmark Dr. Erin's Website: www.drerinellis.com Subscribe to Hope Natural Health on YouTube: https://www.youtube.com/channel/UChHYVmNEu5tKu91EATHhEiA Follow Hope Natural Health on FB: https://www.facebook.com/hopenaturalhealth Sign up for Newsletters here: https://booking.hopenaturalhealth.com/widget/form/VUubL7MNYELduwQL8ssI
Menopause doesn't have to be miserable. Yes, we're going to age, and yes, our hormones are going to change, but we do not have to feel old, exhausted, foggy, and brushed off. In this solo episode of the Medical Disruptor, I walk you through how to actually balance your hormones through perimenopause and menopause, in the order your body actually works. Most women get handed estrogen and sent home, and I'm going to show you why that approach so often misses the real driver, and what you need to address first. I start by clearing up the difference between menopause and perimenopause so you know which stage you're really in, and then I explain why your sex hormones aren't the right place to begin. From there I walk through it in the order that actually matters: first insulin and blood sugar, which almost everyone skips, then cortisol and your stress system, which can quietly hog the raw ingredients your sex hormones need, and then your thyroid, where I explain why a single TSH number is not enough testing. Only after those foundations do I get into sex hormones and hormone therapy, including the real difference between HRT and BHRT, what you're actually being offered, and why the type, dose, and route of delivery matter so much. I also unpack the truth behind the Women's Health Initiative studies, the myth that menopause is simply estrogen deficiency, what estrogen dominance really means, and why testosterone matters for women too. You're not stuck, and you don't have to push your way through this. I'm Dr. E, the NP with the PhD, and I help humans go from medically gaslit to medically empowered. Want more practical health tips? Join my newsletter! https://freechapter.lpages.co/newsletter-opt-in/ "Fine" isn't the same as well. Stop waiting to collapse before someone listens. Build your case: https://freechapter.lpages.co/how-to-build-a-case-for-yourself/ Check us out on social media: https://www.instagram.com/drefratlamandre https://www.facebook.com/drefratlamandre https://www.tiktok.com/@drefratlamandre #functionalmedicine #drefratlamandre #medicaldisruptor #NPwithaPHD #nursepractitioner #medicalgaslighting Chapters 0:00 - Introduction 1:25 - Defining Menopause, Perimenopause & Hormones 3:06 - Why Insulin Comes First 5:38 - Cortisol & Your Stress System 7:21 - Getting Your Thyroid Tested Right 9:15 - Sex Hormones, HRT & Finding Balance Learn more about your ad choices. Visit megaphone.fm/adchoices
You were told to try again. Maybe you were told it was bad luck, or to wait until it happened a third time before anyone would look. Here is what changed this year. In 2026, the American Society for Reproductive Medicine updated its definition of recurrent pregnancy loss for the first time since 2012. Two losses now meet the definition, not three, and a positive test that ended early counts. The old number kept women waiting for a third loss before the investigation even started. Here is the part no one tells you. Meeting the definition gets you a workup. It does not guarantee the workup is complete. After two or more losses, up to half of couples are told the same word. Unexplained. The losses are real. What gets called a complete workup is the question. This episode is the 9 specific things we most often find that are rarely checked before a woman is told her losses were unexplained or simply bad luck. Pull it up. Take notes. Bring it to your next appointment. The 9 patterns: Thyroid, the full panel and antibodies, not just TSH Antiphospholipid antibodies, tested correctly Chronic endometritis The reproductive microbiome, vaginal and seminal The gut, hidden gluten, and inflammation Sperm DNA fragmentation The male partner's full bloodwork Blood sugar and metabolic patterns The nervous system and progesterone These are the areas that sit outside a standard miscarriage workup. A 2012 meta-analysis in Human Reproduction, pooling sixteen studies and nearly three thousand couples, found miscarriage rates rose with sperm DNA damage, with about twice the relative risk. Unexplained rarely means there is nothing to find. It usually means the search stopped at the karyotype, one antiphospholipid test, the anatomy, and a TSH. For the full breakdown of every pattern, read the companion article, Recurrent Pregnancy Loss: The Functional Fertility Approach, at https://fabfertile.com/blogs/learn/recurrent-pregnancy-loss WHAT YOUR CLINIC MISSED The companion guide walks through all 9 of these patterns in more detail, so you can take it to your next appointment and ask the questions. Email hello@fabfertile.ca, subject line MISSED, and we will send you the guide. FUNCTIONAL FERTILITY SECOND OPINION A free 45-minute call where I review your labs, your history, your losses, and your partner's results with you. You leave knowing what your biology has been telling you and what your next decision could be. Email hello@fabfertile.ca, subject line FERTILE, or book here. ABOUT THE HOST I'm Sarah Clark, founder of Fab Fertile and host of Get Pregnant Naturally, a podcast with over one million downloads. My functional fertility team works with couples navigating low AMH and failed IVF, reviewing functional lab results, gut microbiome, food sensitivity, vaginal microbiome, nutrigenomics, HTMA, DUTCH, toxin testing, and bloodwork alongside nervous system work, to help identify patterns that may not have been considered. We work alongside your medical team, not instead of them. Sarah Clark, founder of Fab Fertile, host of Get Pregnant Naturally (1M+ downloads), and author of Fabulously Fertile. If this episode helped, leave a review on Apple Podcasts. It is how other women find this work. TIMESTAMPS 00:00 What "Unexplained" Means and What the 2026 Guideline Changed 01:30 Who's Reviewing Your Case at Fab Fertile 04:00 Thyroid: The Full Panel, Not Just TSH 05:50 Antiphospholipid Antibodies, Tested Correctly 06:30 Chronic Endometritis 07:30 The Reproductive Microbiome 08:30 The Gut, Hidden Gluten, and Inflammation 10:30 What Your Clinic Missed Guide 11:00 Sperm DNA Fragmentation 12:30 The Male Partner's Full Bloodwork 13:50 Blood Sugar and Metabolic Patterns 15:20 The Nervous System and Progesterone 16:30 What "Unexplained" Really Means 17:20 The Functional Fertility Second Opinion
If you've been told your thyroid is "normal" because your TSH came back in range, but you're still exhausted, gaining weight, losing hair, struggling with brain fog, or feeling like a completely different person... this episode is for you. This week, I'm joined by Dr. Amie Hornaman, better known as "The Thyroid Fixer," for an unfiltered conversation about everything conventional medicine often gets wrong about thyroid health. We dive into why TSH isn't enough, the importance of Free T3 and Reverse T3, Hashimoto's, gluten, birth control, metabolic adaptation, over-exercising, under-eating, and why so many women are told they're fine when they clearly are not. We also tackle GLP-1 medications, body positivity, thyroid optimization, and why your symptoms deserve more attention than a single lab value. Whether you're dealing with hypothyroidism, Hashimoto's, stubborn weight gain, hormone issues, or you've simply been dismissed by the healthcare system, this episode will give you a different way to think about your thyroid and your health. Learn more about working with me Shop my masterclasses (learn more in 60-90 minutes than years of dr appointments) Follow me on IG Follow Empowered Mind + Body on IG Get Dr. Amie Hornaman's book and resources here Follow Dr. Amie on IG
If you've ever been told your thyroid labs are "normal" but you still feel exhausted, cold, constipated, anxious, inflamed, or unable to lose weight, this episode is for you. In this episode of The Thyroid Answers Podcast, Dr. Eric Balcavage explores one of the most misunderstood concepts in thyroid care: the difference between a thyroid lab value being normal and being appropriate for your physiology. He explains why thyroid lab markers such as TSH, Free T4, Free T3, Reverse T3, and thyroid antibodies are often interpreted too simplistically and why normal lab values do not always mean healthy thyroid function. Dr. Balcavage breaks down how stress physiology, inflammation, immune activity, gut dysfunction, sleep disruption, nutrient deficiencies, and overall physiologic state can influence thyroid hormone production and T4-to-T3 conversion. He also explains why many thyroid patterns may actually represent adaptive responses rather than broken physiology. You'll learn how to interpret thyroid labs within the context of symptoms, health history, inflammatory markers, and overall physiologic state, and why focusing solely on optimizing lab values often fails to restore true health and well-being. Whether you're struggling with persistent hypothyroid symptoms despite normal labs or you're trying to better understand your thyroid physiology, this episode provides a deeper framework for understanding what your thyroid labs may really be telling you. In This Episode, You'll Learn: Why normal labs don't always equal healthy thyroid function How to determine if your thyroid labs are actually appropriate for your physiology The role stress, inflammation, and lifestyle factors play in thyroid hormone regulation Why low T3 and poor conversion may be adaptive responses Why thyroid medication doesn't always resolve symptoms What to focus on beyond lab values to support better thyroid health Resources Mentioned:
For most people, donor eggs is at the bottom of the list. It is not where you wanted to land. And if your clinic is recommending it, something in you is saying there has to be more to look at first. Here is what we see every week. The donor egg recommendation rarely arrives after a complete workup. It arrives after looking at the AMH, the FSH, the follicle count, maybe a basic semen analysis, and maybe being told your TSH is normal. Those numbers are real. The diagnosis is real. What gets called complete is the question. This episode is the 11 specific things we most often find skipped before the recommendation gets made. Pull it up. Take notes. Bring it to your next appointment. The 11 patterns: 1. Thyroid, the full panel, not just TSH 2. The gut, including H. pylori 3. Hidden food sensitivities 4. Medications you are already on that affect fertility 5. The vaginal microbiome 6. The seminal microbiome 7. The male partner's full bloodwork 8. Sperm DNA fragmentation 9. Vaginal and seminal cross-contamination between partners 10. The nervous system and HPA axis 11. Liver function and hormone clearance These are the tests that sit outside the standard fertility workup. A 2024 study in Archives of Gynecology and Obstetrics found that ovarian reserve markers like AMH do not significantly predict natural conception in women with regular cycles. The donor egg recommendation comes from one snapshot, not the full investigation. If this is the first episode you have landed on in this series, go back and listen to "Told Donor Eggs Are Your Only Option? Ask This First," then "How Long Should I Try With My Own Eggs Before Donor Eggs?" then "The Gut Findings Your Clinic Did Not Look For," and "Multiple Failed IVF And Told Donor Eggs?" This episode brings all of it together. WHAT YOUR CLINIC MISSED The companion guide walks through all 11 of these patterns in more detail, so you can take it to your next appointment and ask the questions. Email hello@fabfertile.ca, subject line MISSED, and we will send you the guide. FUNCTIONAL FERTILITY SECOND OPINION A free 45-minute call where I review your labs, your history, and your partner's results with you. You leave knowing what your biology has been telling you and what your next decision could be. Email hello@fabfertile.ca, subject line FERTILE, or book here. ABOUT THE HOST I'm Sarah Clark, founder of Fab Fertile and host of Get Pregnant Naturally, a podcast with over one million downloads. My functional fertility team works with couples navigating low AMH and failed IVF, reviewing functional lab results, gut microbiome, food sensitivity, vaginal microbiome, nutrigenomics, HTMA, DUTCH, toxin testing, and bloodwork alongside nervous system work, to help identify patterns that may not have been considered. We work alongside your medical team, not instead of them. Sarah Clark, founder of Fab Fertile, host of Get Pregnant Naturally (1M+ downloads), and author of Fabulously Fertile. If this episode helped, leave a review on Apple Podcasts. It is how other women find this work. TIMESTAMPS 00:00 The Donor Egg Recommendation and What Gets Called Complete 01:00 Who's Reviewing Your Case at Fab Fertile 02:00 Thyroid: The Full Panel, Not Just TSH 03:00 The Gut and H. pylori 04:00 Hidden Food Sensitivities 05:00 Medications That Affect Fertility 06:30 The Vaginal Microbiome 08:00 The Seminal Microbiome 08:30 The Male Partner's Full Bloodwork 09:00 Sperm DNA Fragmentation 09:30 Cross-Contamination Between Partners 11:00 The Nervous System and HPA Axis 11:30 Liver Function and Hormone Clearance 13:00 The Functional Fertility Second Opinion
Your body after a baby was never a calorie problem. It is a metabolic one. In this Her Stack episode I am walking you through exactly how to restore your metabolism so body composition follows. The goal is not weight loss. The goal is metabolic restoration. Body comp is downstream. I am breaking down the four drivers that actually run body composition (insulin, thyroid, sleep, growth hormone), the four pillars to address them (nutrition, lifestyle, supplements, peptides), and the exact peptide sequencing for women. Plus my honest take on GLP-1s including semaglutide, tirzepatide, and retatrutide, where they actually fit, and why microdosing makes more sense than chasing the scale. I also share what nobody talks about. Eating less postpartum often makes body composition worse. Breastfeeding is sequencing, not failure. Growth hormone is the layer women never hear about, so they plateau and blame their age when it was a fixable signal the whole time. Join The LongHer Life for women-specific guidance on peptides, hormones, and longevity. I TALK ABOUT: 00:00 Welcome back to the Her Stack series 00:53 Updates: working with me one-on-one and my new peptide planner 06:15 Why body composition not weight, and why metabolism not calories 07:01 The four drivers and four pillars framework 09:00 Driver 1: Insulin resistance and why stubborn middle fat is an insulin problem, not a calorie problem 11:30 Driver 2: Thyroid, and why TSH alone misses Free T3 (the worker hormone) 14:50 Driver 3: Sleep, cortisol, and the loop back to insulin resistance 19:32 Driver 4: Growth hormone, the layer nobody talks about that's blunted postpartum and through aging 22:19 The labs to actually ask for: fasting insulin, Free T3, IGF-1, DHEA-S, plus a 2-week CGM 24:30 Pillar 1: Nutrition (protein floor of 120g, leucine at every meal, food order, fiber, and why you should NOT under-eat) 28:06 Why leucine flips the muscle-building switch 35:00 Pillar 2: Lifestyle and biohacking (lift 3x a week, walk 7-10k steps, zone 2, cold and heat, red light, and the fringe tier honestly) 45:30 Pillar 3: Supplements (creatine, magnesium glycinate, myo-inositol, omega-3, berberine, and breastfeeding sequencing) 51:01 Berberine, AMPK, and "nature's metformin" 55:30 Pillar 4: The peptide stack starts here with AOD-9604 56:00 AOD-9604, the growth hormone fragment, why I am personally taking it right now 01:02:00 MOTS-c, the "exercise in a molecule" mitochondrial peptide 01:05:00 5-Amino-1MQ and releasing the brake on fat cells 01:07:00 Sermorelin, the gentle GH entry (what a secretagogue actually is) 01:10:00 CJC-1295, Ipamorelin, and Tesamorelin for post-weaning GH restoration 01:13:00 The GLP-1 honest take: semaglutide, tirzepatide, and the retatrutide question 01:14:00 Why retatrutide is called the triple agonist and where it fits (and where it doesn't) 01:19:27 Recap and wrap-up RESOURCES: Work with me one-on-one on your peptide stack and protocol. The Her Stack Planner, the first peptide tracking journal built around female biology. Free Peptide Masterclass for Women. Join The LongHer Life for women-specific guidance on peptides, hormones, and longevity. LET'S CONNECT: Instagram, TikTok, Facebook Shop my favorite health products Listen on Spotify, Apple Podcasts, YouTube Music
Deprescribing thyroid and other meds in older adultsCan I safely take serrapeptase for longer than four weeks?I want to take nattokinase but isn't there a 'clot dislodging' risk?Could you discuss C. difficile and how to treat it?
Most people with elevated thyroid antibodies are told, “Don't worry, your thyroid is fine.” But what does the research actually say?In this episode of Reversing Hashimoto's, Dr. Anshul Gupta explores the hidden impact of thyroid antibodies, including their connection to thyroid tissue destruction, infertility, miscarriage, hormonal imbalances, brain fog, autoimmune disease, and long-term health risks. Learn why normal TSH levels don't always mean optimal thyroid health, how thyroid antibodies affect the entire body, and what current research reveals about their significance.Dr. Gupta also shares practical strategies for lowering thyroid antibodies and a real patient success story that demonstrates what's possible when the root causes of autoimmune thyroid disease are addressed.If you've been told your antibodies don't matter, this episode may change the way you think about your thyroid health.
In today's LIVE-TALK podcast, we chat about our recently published series of books. We highlight Dr. Blevins' prolific writing output in the PWN self-published book series, with five titles on pituitary adenomas, diabetes insipidus, Cushing's, hypopituitarism, and pituitary disorders; a TSH-producing tumor book (in editing); a prolactinoma volume heading to the publisher; and an acromegaly book planned.
For years, an indeterminate thyroid biopsy meant diagnostic surgery but molecular testing is now changing that reality entirely. On this episode of the BackTable ENT podcast, Dr. Ashley Agan interviews endocrinologist Dr. Erik Alexander about how molecular testing and a systematic, layered approach to thyroid nodule evaluation are reducing diagnostic surgeries and enabling more individualized patient care. --- Get the BackTable apphttps://www.backtable.com/app --- This podcast is supported by Veracytehttps://www.veracyte.com/ --- Timestamps 00:00 - Introduction02:48 - Incidence, Presentation, and Workup of Thyroid Nodules 06:26 - Hormonal Impact and Indications for FNA 10:49 - FNA workflow and Bethesda Categories 16:10 - Role of Molecular Testing for Indeterminate Nodules19:59 - Evolution of Molecular Testing and Afirma 23:51 - Basics of DNA based Testing and RNA based Testing 28:34 - Comparing DNA based and RNA Based Testing 32:10 - Utility of Molecular Testing and Sampling Techniques 35:55 - Cost Coverage and Practical Limits39:20 - Clinical Implications and Future Impact42:00 - Final Takeaways --- More about this episode Together they walk through the full evaluation pathway, including ultrasound risk stratification using the TI-RADS criteria, the role of TSH testing, and how FNA indications have shifted from biopsying every solid nodule to a more selective, risk-adapted approach. The discussion covers the Bethesda classification system and addresses why the one-third of patients landing in indeterminate categories (Bethesda III, IV, and V) have historically been the most challenging and most overtreated group. The conversation then explores molecular diagnostics as an additional layer of risk assessment, highlighting key differences between DNA-based mutation panels and RNA-based expression classifiers. Dr. Alexander also discusses practical considerations like insurance coverage, sampling technique, turnaround time, and the future potential of molecular testing to move beyond diagnosis toward individualized prognosis. --- Resources American College of Radiology: TI-Rads Guidelines https://edge.sitecorecloud.io/americancoldf5f-acrorgf92a-productioncb02-3650/media/ACR/Files/RADS/TI-RADS/TI-RADS-Assessment-Categories.pdf American Thyroid Association - Nodule Guidelineshttps://pmc.ncbi.nlm.nih.gov/articles/PMC4739132/ Bethesda System for Reporting Thyroid Ctyopathology https://www.ncbi.nlm.nih.gov/books/NBK278969/table/thyroid-nod-canc-eld.T.bethesda_system_f/ --- BackTable ENT & Allergy is the go-to podcast for otolaryngologists, allergists, and head and neck surgeons. Download the free BackTable app to get early access to new episodes, cases, and courses curated by physicians in your specialty. ► https://www.backtable.com/app
You have done IVF more than once. Maybe twice. Maybe three times. Maybe more. Each cycle they tweaked the protocol. Higher dose. Lower dose. Different stimulation drug. Different trigger. Added growth hormone. Added DHEA. Mini IVF. Dual stim. Each cycle the protocol changed. And now they are telling you donor eggs. Here is the question this episode is about. They changed the protocol every time. Did anyone look at what was already in your body when each of those protocols arrived? That is what this episode is about. The layer underneath every protocol. In this episode: - Protocol vs system: what your clinic was trained to adjust, and what nobody adjusted across any of your cycles - Why the donor egg conversation arrives after the only variable your clinic was trained to address has been exhausted, not after a full review of your body - The thyroid, iron, B12, vitamin D, inflammation, gut, cortisol, mineral, vaginal microbiome, and blood sugar markers that did not change between cycle 1 and cycle 5 - Why we look at ferritin against 80 to 100 going into IVF, not the lab reference of 15 - What a 2024 study in Archives of Gynecology and Obstetrics found about ovarian reserve markers and natural conception — and why donor eggs gets recommended on markers the literature itself does not support If this is the first episode you have landed on in this series, go back and listen to "Told Donor Eggs Are Your Only Option? Ask This First," then "How Long Should I Try With My Own Eggs Before Donor Eggs?" and "The Gut Findings Your Clinic Did Not Look For." This episode builds on all three. ——— WHAT YOUR CLINIC MISSED The full thyroid panel, not just a TSH. The iron panel that flags ferritin against the fertility target. The gut microbiome testing your REI does not order. The inflammatory markers they tell you are normal. And the male side that almost nobody investigates. Email hello@fabfertile.ca, subject line MISSED, and we will send you the guide. ——— FUNCTIONAL FERTILITY SECOND OPINION A free 45-minute call where I review your labs, your history, and your partner's results with you. You leave knowing what your biology has been telling you and what your next decision could be. Email hello@fabfertile.ca, subject line FERTILE, or book here. ——— ABOUT THE HOST I'm Sarah Clark, founder of Fab Fertile and host of Get Pregnant Naturally, a podcast with over one million downloads. My functional fertility team works with couples navigating low AMH and failed IVF, reviewing functional lab results, gut microbiome, food sensitivity, vaginal microbiome, nutrigenomics, HTMA, DUTCH, toxin testing, and bloodwork alongside nervous system work, to help identify patterns that may not have been considered. We work alongside your medical team, not instead of them. Sarah Clark, founder of Fab Fertile, host of Get Pregnant Naturally (1M+ downloads), and author of Fabulously Fertile. ——— If this episode helped, leave a review on Apple Podcasts. It is how other women find this work. ——— TIMESTAMPS 00:00 The Protocol Changed Every Time. Did Anyone Change You? 01:00 Who's Reviewing Your Case at Fab Fertile 02:00 Protocol vs System: The Layer Underneath Every IVF 03:00 What Your Body Brought to Every Cycle 04:30 What the 2024 Research Says About AMH 06:00 The Markers That Did Not Change Between Cycles 07:30 Why Multiple Tests Are Not One Test 09:00 The Donor Egg Recommendation With Half the Data 10:30 The Functional Fertility Second Opinion
Welcome back to our weekend Cabral HouseCall shows! This is where we answer our community's wellness, weight loss, and anti-aging questions to help people get back on track! Check out today's questions: Kay: Hi Dr. Cabral, Thanks for your very informative and interesting podcasts. How would you advise a post-menopausal 60 y.o family member if they tested low in ferritin (39.4 ng/mL)? I've read that this biomarker shows how much energy your body's cells have and low levels would result in symptoms like fatigue, low energy/easily tired and excessive hair shedding. This family member suffers from these symptoms. Other biomarkers revealed low AM cortisol and low LDL-C/ApoB ratio (1.1) and low basal metabolic rate of 1143 kcals/day. Although her TSH tested normal (1.3 uIU/mL), she's been on levothyroxine 75 mcg to manage hypothyroid. Her high-sensitivity CRP was not optimal at 1.49 mg/L and she has a family history of heart disease. What would you recommend for this family member? Thanks Earl: I am currently on 20 mg of lisinopril daily. Also, my GFR is 62. Would either of these be a concern when considering creatine? Alesi: Dr.Cabral, can you please explain Alpha-gal syndrom? Why does it happen, how to confirm it by testing and how would you approach it? Is it treatable? Thank you Peter: Hello, Dr.Cabral. I am an integrative health practitioner and would like to thank you for helping me understand the underlying causes of human imbalances. There is one thing that makes no sense to me though…regarding IgG testing, why would you recommend to test every year? Why doesn't suffice to test once and simply stay away from intolerant food items? Why would these intolerances change? Also, in my country there are IgG4 vs IgG1-3 testing options, what are the differences? Thank you very much for your time and knowledge you share with us. Dipali: Hi I want to start 7 days detox plan, I already did your minerals and heavy metal test, I got my results back. My question is I am taking berberine, oregano oil and magnesium citrate,( I am prediabetic my Hba1c is 6.2)do I need to stop before starting detox method. Thanks Thank you for tuning into today's Cabral HouseCall and be sure to check back tomorrow where we answer more of our community's questions! - - - Show Notes and Resources: StephenCabral.com/3774 - - - Get a FREE Copy of Dr. Cabral's Book: The Rain Barrel Effect - - - Join the Community & Get Your Questions Answered: CabralSupportGroup.com - - - Dr. Cabral's Most Popular At-Home Lab Tests: > Complete Minerals & Metals Test (Test for mineral imbalances & heavy metal toxicity) - - - > Complete Candida, Metabolic & Vitamins Test (Test for 75 biomarkers including yeast & bacterial gut overgrowth, as well as vitamin levels) - - - > Complete Stress, Mood & Metabolism Test (Discover your complete thyroid, adrenal, hormone, vitamin D & insulin levels) - - - > Complete Food Sensitivity Test (Find out your hidden food sensitivities) - - - > Complete Omega-3 & Inflammation Test (Discover your levels of inflammation related to your omega-6 to omega-3 levels) - - - Get Your Question Answered On An Upcoming HouseCall: StephenCabral.com/askcabral - - - Would You Take 30 Seconds To Rate & Review The Cabral Concept? The best way to help me spread our mission of true natural health is to pass on the good word, and I read and appreciate every review!
Fontes do episódio aqui:https://portal.afya.com.br/podcasts/afya-news/05-06-2026Nesta sexta-feira, analisamos atualizações em endocrinologia reprodutiva, uma revolução na terapia celular oncológica e o papel dos jogos sérios no julgamento clínico. Abordamos as diretrizes atualizadas da American Thyroid Association, que estabelecem valores de referência por trimestre para TSH e T4, priorizando o rastreamento direcionado. Detalhamos os dados promissores da nova terapia CAR-T in vivo da Legend Biotech para linfoma não-Hodgkin, que gera as células de defesa diretamente dentro do corpo do paciente. Por fim, discutimos no Radar um estudo do JAMA que comprova como o jogo eletrônico Night Shift reduziu erros médicos e a subestimativa de traumas em idosos na emergência. Afya News. Informação médica confiável e atualizada no seu tempo.
If you are focusing on improving your FatMax in 2026, you're likely wasting time and money. Not only is fat a more expensive substrate to burn than carbohydrate (you get less energy for the same amount of oxygen by oxidising fat), but the Fatmax number you see in your lab report is mostly noise and very little signal. In today's episode of That Triathlon Show I'll explain exactly why that is, but I'll also give you a tool to evaluate any test or measure that you might (or might not) want to be tracking, from Time Trials to VO2max, HRV and various biomarkers like ferritin and testosterone. HIGHLIGHTS AND KEY TOPICS: What is Fatmax and Maximal Rate of Fat Oxidation? How reliable is Fatmax testing? How to measure the noise of a test using the Coefficient of Variation (CV) How to calculate the Smallest Detectable Change (SDC) of any test or measure Why the SDC of Fatmax is the equivalent of you having to go from 300 to 384W for your 20-minute power to be able to say that this was real improvement and not just noise (!!) CVs and CV ranges for common tests and measures used in triathlon, Ironman and other endurance sports, including Time Trials, Time To Exhaustion, VO2max, lactate and ventilatory thresholds, economy and gross efficiency, lactate concentration, Critical Power and W', HRV, ferritin, testosterone, TSH and more Why carbohydrate is a 7% more efficient energy substrate than fat, and why you should be oxidising carbs in your next Ironman. DETAILED EPISODE SHOWNOTES: We have detailed shownotes for all of our episodes. The shownotes are basically the podcast episode in written form, that you can read in 5-10 minutes. They are not transcriptions, but they are also not just surface-level overviews. They provide detailed insights and timestamps for each episode, and are great especially for later review, after you've already listened to an episode. The shownotes for today's episode can be found at https://scientifictriathlon.com/tts700/ LINKS AND RESOURCES: Full bibliography in the shownotes: https://scientifictriathlon.com/tts700/ WHAT SHOULD I LISTEN TO NEXT? If you enjoyed this episode, I think you'll love the following episodes, related to sports science and (the third episode listed) fat adaptation and performance. The replication crisis in sports science with Joe Warne, PhD | EP#468 The Skeptic's Guide To Sports Science with Nicholas Tiller, PhD | EP#239 High carbohydrate, low carbohydrate, or periodised carbohydrate intake with Louise Burke, PhD | EP#236 You can find our full episode archives here, where you can filter for categories such as Triathlon Training, Racing, Science & Physiology, Swimming, Cycling, Running etc. You can also find separate archives for specific series of episodes I've done, specifically Q&A episodes, TTS Thursday episodes, and Beginner Tips episodes. LEARN MORE ABOUT SCIENTIFIC TRIATHLON: The Scientific Triathlon website is the home of That Triathlon Show and everything else that we do Contact us through our contact form or email me directly (note - email/contact form messages get responded to much more quickly than Instagram DMs) Subscribe to our Newsletter Follow us on Instagram Learn more about our coaching, training plans, and training camps. We have something to offer for everybody from beginners to professionals. HOW CAN I SUPPORT THAT TRIATHLON SHOW (FOR FREE)? I really appreciate you reading this and considering helping the show! If you love the show and want to support it to help ensure it sticks around, there are a few very simple things you can do, at no cost other than a minute of your time. Subscribe to the podcast in your podcast app to automatically get all new episodes as they are released. Tell your friends, internet and social media friends, acquaintances and triathlon frenemies about the podcast. Word of mouth is the best way to grow the podcast by far! Rate and review the podcast (ideally five stars of course!) in your podcast app of choice (Spotify and Apple Podcasts are the biggest and most important ones). Share episodes online and on social media. Share your favourite episodes in your Instagram stories, start a discussion about interesting episodes on forums, reference them in your blog or Substack. SPONSORS: Precision Fuel & Hydration produce our favourite gels, sports drinks, and electrolyte and carbohydrate products here at That Triathlon Show and Scientific Triathlon. Use the free Fuel & Hydration Planner to get a personalised plan for your carbohydrate, sodium and fluid intake in your next event, and get 15% off your first 2026 order by using the code TTS2026 at checkout. Rouvy is hands down the most complete indoor cycling platform for triathletes. Among their thousands of beautiful bike courses from all around the world, all filmed in stunning quality, they have over 75 IRONMAN and IRONMAN 70.3 race courses plus 20+ Challenge Family courses, so you can pre-ride your race from home. Real gradients, real visuals, and real feel! Head to rouvy.com and use the code TTS to get your first month free on top of a 7-day free trial. Effortless Swimming produce the best swim goggles for triathletes and open water swimmers. Their NanoClear anti-fog lenses give you clear, fog-free vision that lasts and doesn't wear off. Don't let foggy or leaky goggles ruin another swim. Go to shop.effortlessswimming.com and use the code TTS15 to get 15% off your goggles, and get a free two-month Effortless Swimming course membership.LEARN MORE ABOUT SCIENTIFIC TRIATHLON: The Scientific Triathlon website is the home of That Triathlon Show and everything else that we doContact us through our contact form or email me directly (note - email/contact form messages get responded to much more quickly than Instagram DMs)Subscribe to our NewsletterFollow us on InstagramLearn more about our coaching, training plans, and training camps. We have something to offer for everybody from beginners to professionals. HOW CAN I SUPPORT THAT TRIATHLON SHOW (FOR FREE)? I really appreciate you reading this and considering helping the show! If you love the show and want to support it to help ensure it sticks around, there are a few very simple things you can do, at no cost other than a minute of your time. Subscribe to the podcast in your podcast app to automatically get all new episodes as they are released.Tell your friends, internet and social media friends, acquaintances and triathlon frenemies about the podcast. Word of mouth is the best way to grow the podcast by far! Rate and review the podcast (ideally five stars of course!) in your podcast app of choice (Spotify and Apple Podcasts are the biggest and most important ones).Share episodes online and on social media. Share your favourite episodes in your Instagram stories, start a discussion about interesting episodes on forums, reference them in your blog or Substack. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
You've heard about hot flashes. Maybe you've even had them. But the hormone shift that's quietly dismantling your mood, your metabolism, your sleep, and your sense of self? That started years before menopause and most women have no idea. In this solo episode, Dr. Terri DeNeui maps the full three-decade hormone timeline every woman needs to understand: the testosterone loss that begins in your 30s (and its devastating, and overlooked connection to depression), the progesterone decline that hits like a wall in your 40s, and the estrogen fluctuation that makes the late 40s and early 50s the most miserable stretch for many women. She also makes the case for thyroid as the most underdiagnosed piece of the puzzle and explains why a normal TSH doesn't mean your thyroid is actually working. Along the way, she takes on the antidepressant default, sharing her own doctoral research showing that women who optimized their testosterone resolved their depression entirely and the birth control pill habit that well-meaning gynecologists are still prescribing after 40, despite a very real and elevated stroke risk. This episode is for women in their 30s, 40s, and 50s who've been told their labs are fine but know something is wrong and for anyone who wants to understand what's actually happening before settling for symptoms management. What you'll discover: Why testosterone, not estrogen is the first hormone women lose, and what that means for mood, focus, and body composition [04:50] The doctoral research that changed how Dr. Terri thinks about depression in women and antidepressants [05:17] Progesterone: the calming hormone that disappears in your 40s and why heavy, painful cycles are a deficiency not a life sentence [07:19] Why birth control pills after 40 carry serious stroke risk and what to use instead [08:50] The estrogen fluctuation that makes the late 40s and early 50s the hardest stretch for most women [09:43] Why "normal" lab ranges are based on a sick, unhealthy population and where you actually want your numbers [19:44] Thyroid: the most underdiagnosed condition in older women and why TSH alone doesn't tell the full story [16:33] T4 vs. T3 — and the key enzyme most women are quietly losing as they age [17:26] Why women need hormone optimization across the full lifespan not just to manage symptoms during the transition [14:04] The bottom line: your hormones don't just affect how you feel during menopause they shape every decade of your health. Finding a clinician who understands optimization, not just symptom management, changes everything. The Dr. Terri Show is presented by EVEXIAS Health Solutions. For more, visit: https://www.evexias.com Connect with Dr. Terri:
Your clinic told you donor eggs. You walked out wondering how much time you actually have left. Whether waiting six months means missing your window. Whether trying with your own eggs one more time is brave or stupid. The honest answer is longer than your clinic implied. And the window is not your AMH number. In this episode: - Why a 2024 study in Archives of Gynecology and Obstetrics found that ovarian reserve markers like AMH do not significantly predict natural conception in women with regular cycles - What the 90-day window before ovulation actually is, and why the eggs you work with six months from now are not the eggs you are working with today - The inputs your clinic's timeline assumed would not change: mitochondrial function, inflammation, iron, B12, zinc, vitamin D, cortisol patterns, toxic load - The clinical pattern we see over more than a decade of cases: month zero to six is where the picture comes into view, twelve to eighteen months is where it can start to move substantially - Why some pictures do not move, and why that is still a reason to look before you decide If this is the first episode you have landed on in this series, go back and listen to "Told Donor Eggs Are Your Only Option? Ask This First" and then "The Gut Findings Your Clinic Did Not Look For." This episode builds on both. ——— WHAT YOUR CLINIC MISSED The full thyroid panel, not just a TSH. The iron panel that flags ferritin. The gut microbiome testing that your REI does not order. The inflammatory markers no one notices. The male side that almost no one investigates. Email hello@fabfertile.ca, subject line MISSED, and we will send you the guide. ——— FUNCTIONAL FERTILITY SECOND OPINION A free 45-minute call where I review your labs, your history, and your partner's results with you. You leave knowing what your biology has been telling you and what your next decision could be. Email hello@fabfertile.ca, subject line FERTILE, or book here. ——— ABOUT THE HOST Now in its eighth year, Get Pregnant Naturally was one of the first podcasts dedicated to the functional fertility approach for low AMH and failed IVF. Hosted by Sarah Clark, founder of Fab Fertile, author of Fabulously Fertile, and host of a podcast with over one million downloads. Fab Fertile is a functional fertility team that works with couples to review the lab work most fertility clinics do not run: gut microbiome, food sensitivity, vaginal microbiome, nutrigenomics, HTMA, DUTCH, full thyroid panel, the iron panel, and inflammation markers, alongside nervous system work. Each week Sarah brings you what the team sees across more than a decade of cases. Sarah Clark, founder of Fab Fertile, host of Get Pregnant Naturally (1M+ downloads), and author of Fabulously Fertile. ——— If this episode helped, leave a review on Apple Podcasts. It is how other women find this work. ——— TIMESTAMPS 00:00 The Donor Egg Recommendation and the Real Question 01:00 Who's Reviewing Your Case at Fab Fertile 01:30 AMH Is Not the Countdown Clock 03:00 The 90-Day Window Before Ovulation 04:30 What Actually Changes In 90 Days 07:00 The Fab Fertile Method: What We Investigate 08:30 Why Some Cases Do Not Shift 09:30 The Functional Fertility Second Opinion
Discover 7 key signs of a slow thyroid and learn how to distinguish between Hashimoto's and general hypothyroidism. Plus, discover natural ways to support thyroid health and address common thyroid problems naturally.
In this Her Stack series episode, I open up about maternal mental health, postpartum anxiety, and the invisible biological load mothers carry long after the six-week checkup is over. This episode is not just for the newly postpartum mother. It is for the mother whose kids are four, eight, fifteen, and still asking herself why she does not feel like herself. I share why motherhood structurally changes the brain, hormones, and nervous system, and why so many mothers are left feeling anxious, foggy, depleted, or unlike themselves without ever being properly screened or supported. I walk you through the science of the postpartum neurosteroid withdrawal, the gray matter changes that persist for years, and the five-system map underneath maternal brain fog. Then I break down the full four-pillar protocol I use with my one-to-one clients: foundational nutrition, lifestyle and biohacking tools, the supplement layer including some of the most under-discussed compounds for the maternal brain, and the advanced peptide layer including Semax, Selank, NAD+, and bioregulators. This is the episode every mother needs. Send it to one. Join The LongHer Life for women-specific guidance on peptides, hormones, and longevity. I TALK ABOUT: 02:00 - My free peptide masterclass for moms next week 04:10 — Why maternal mental health is not just a six-week postpartum issue 06:30 — The numbers every mother should know (and the screening gap that explains everything) 08:20 — How pregnancy structurally changes the brain (Nature Neuroscience, 2017) 11:40 — The neurosteroid withdrawal nobody warned you about, and the FDA's $34,000 drug that proves it is real 13:50 — Pillar 1: DHA, protein, ferritin, blood sugar stability, and methylated Bs for the maternal brain 22:40 — Pillar 2: Protected sleep cycles, morning sunlight, vagal nerve activation, and red light to the brain 28:00 — Yoga nidra and NSDR as the workaround for mothers who cannot engineer a protected sleep cycle 32:45 — Simplifying routines, meals, outfits, and planning to reduce mental load 35:00 — Co-regulation: Why one hour of real adult conversation is medicine 38:40 — Creatine for maternal mental health, depression support, and cognitive fatigue in sleep-deprived moms 40:50 — Saffron and inositol for postpartum mood, anxiety, racing thoughts, and the "can't shut off the brain" symptoms 42:15 — Magnesium L-threonate, glycine, vitamin D, and low-dose methylene blue for sleep, brain fog, mitochondrial support, and nervous system balance 45:25 — Why peptides are an advanced layer and should come after nutrition, lifestyle, and supplement foundations 46:10 — Semax and Selank for anxiety, cortisol support, BDNF, dopamine, brain fog, memory, and maternal brain support 50:00 — NAD+ and bioregulators (Cortagen, Cerluten, Epithalon) for maternal energy, neuronal support, circadian rhythm, melatonin, sleep, and long-term brain health 58:15 — Why postpartum anxiety and depression need different kinds of support, and why SSRIs work for some mothers and not others 1:00:00 — Why lingering symptoms matter and which labs mothers should check RESOURCES: Labs to ask your provider for: TSH, free T3, free T4, reverse T3, ferritin, vitamin D, DHA panel Join The LongHer Life for women-specific guidance on peptides, hormones, and longevity. Free Peptide Masterclass for Moms: Join the waitlist for the next live class. The Her Stack Planner: The first peptide tracking journal built around female biology. Crisis support: 988 in the US, 988 in Canada PRODUCTS MENTIONED: Supplements DHA (omega-3) Creatine monohydrate Saffron (Crocus sativus extract) Inositol (myo + d-chiro blend) Glycine Magnesium L-threonate (BiOptimizers code: BIOHACKINGBRITTANY) Vitamin D Lion's mane mushroom Bacopa monnieri Methylated B vitamins (methylcobalamin, methylfolate, P5P) Methylene blue (low dose, pharmaceutical USP only) Peptides Semax Selank NAD+ options NOVOS code: BIOHACKINGBRITTANY Nuchido TIME+ code: BIOHACKINGBRITTANY Nasal spray (Synchronicity Health code: BIOHACKINGBRITTANY) Bioregulators Cortagen Cerluten Epithalon LET'S CONNECT: Instagram, TikTok, Facebook Shop my favorite health products Listen on Spotify, Apple Podcasts, YouTube Music
If you've been trying everything to fix your thyroid or iron issues — medications, supplements, protocols, lab optimization, detoxes, gut healing, hormone balancing — and you still don't feel well… this episode may explain why. In this episode of the Thyroid Answers Podcast, Dr. Eric Balcavage breaks down why so many thyroid and iron protocols fail, even when lab values improve. You'll learn why "optimizing" TSH, T3, ferritin, iron, cortisol, hormones, or micronutrients often doesn't create lasting results… and why the real issue may have nothing to do with deficiency or dysfunction at all. Dr. Balcavage explains the concept of state-based physiology — how your body shifts between resilience, chronic strain, and defensive survival states based on stress load and available capacity. He also explains why many common thyroid and iron patterns are actually adaptive responses, not broken physiology. If you've been stuck chasing protocols, supplements, medications, or temporary improvements that never seem to last… this episode will help you understand why. What You'll Learn: • Why thyroid and iron protocols often stop working over time • Why optimizing lab values doesn't always improve symptoms • The difference between adaptive physiology and dysfunction • Why low T3 and iron dysregulation are often stress adaptations • How short-term symptom improvement can become a long-term trap • Why some people react poorly to supplements, hormones, or medications • The connection between inflammation, metabolism, and capacity • What "state-based physiology" means and why it matters • The three primary physiologic states: resilience, chronic strain, and overload • Why the same supplement or medication can help one person and harm another • How chronic stress changes thyroid conversion and iron regulation • Why more T3, iron, detoxing, or supplementation may worsen symptoms • The hidden problem with protocol-based medicine and optimization culture • Why symptoms and labs are often signals… not the root problem • How to begin reducing load and rebuilding physiologic capacity Learn More About Dr. Eric Balcavage Dr. Eric Balcavage is the co-author of The Thyroid Debacle and the creator of: • State-Based Medicine™ • The Adaptive Thyroid Model™ • The Strategic Thyroid Solution™ His work focuses on helping patients and practitioners understand thyroid physiology through the lens of metabolic stress, adaptation, and whole-body regulation. Dr. Balcavage's new book, Is This The Hill? releases later this year. Get on the waitlist to learn more and get exclusive bonus content here: drericbalcavage.com/hill Connect With Dr. Eric Balcavage Website: https://www.drbalcavage.com Instagram: https://www.instagram.com/drericbalcavage Facebook: https://www.facebook.com/drericbalcavage YouTube: https://www.youtube.com/@drericbalcavage If you enjoyed this episode, be sure to subscribe, leave a review, and share it with someone who's been stuck chasing protocols, supplements, or lab optimization without lasting results.
Have you been told your thyroid is normal, but you are still gaining weight, losing hair, exhausted by 3 PM, and living in a fog? If you have done everything right, clean eating, consistent exercise, and supplements, and nothing is working, this episode may finally give you the answer you have been looking for. It is not you. It is your thyroid.In this episode, Dr. Shivani Gupta sits down with Dr. Amie Hornaman, functional medicine thyroid specialist, host of The Thyroid and Hormone Fixer Podcast, and author of the new book The Thyroid Fix. Dr. Hornaman spent years being dismissed by six different conventional doctors before a seventh finally diagnosed her with hypothyroidism. Even then, the standard T4-only prescription left her no better. Backed by decades of clinical experience and the science of T3 conversion, reverse T3, and the thyroid-adrenal-hormone triangle, she breaks down exactly why so many women are undertreated and what to do about it.Dr. Hornaman shares her own story of gaining 40 pounds while competing in figure competitions and eating nothing but chicken, broccoli, and asparagus, and how it led her into functional medicine and eventually to building one of the most trusted thyroid practices in the country. Dr. Shivani also shares her personal journey from subclinical hypothyroidism to Armour Thyroid to discovering that even natural NDT was not fully working for her body. If you are a woman over 35 navigating perimenopause, unexplained weight gain, brain fog, or fatigue, and your doctor keeps telling you that you are fine, this episode is for you.WHAT YOU'LL LEARNWhy a normal TSH does not mean your thyroid is optimized, and the 5 tests every woman actually needs to ask for, including reverse T3 and TPO antibodiesThe T4-to-T3 conversion problem: why Synthroid and levothyroxine fail many women, and why T4-only treatment keeps you stuck in a low-energy, weight-gain cycleWhy natural desiccated thyroid like Armour and NP Thyroid is not automatically the answer, and how 80 percent T4 in NDT can still push you into reverse T3 lockdown modeHow perimenopause hormones trigger thyroid dysfunction, and the adrenal-progesterone-estrogen-TBG cascade that most doctors are not addressingThe Ayurvedic and lifestyle foundation: why calming inflammation, supporting digestion, and reducing cortisol are non-negotiables before thyroid hormone replacement can workDr. Hornaman's FIX Method, including the supplement, nutrition, and hormone replacement framework that has helped thousands of women get their lives backRESOURCES MENTIONED:The Inflammation Code (book)Fusionary Formulas Supplements — use code CODE15 for 15% off your first order https://fusionaryformulas.com/?utm_source=Show+Notes&utm_medium=Show+notes+&utm_campaign=Podcast+promo&utm_id=The+Inflammation+Code+Podcast7-Day Inflammation Detox ChallengeWork with Dr. Shivani — Free Discovery Call
What if your "normal" thyroid labs aren't telling the full story? In this eye-opening episode of The Girlfriend Doctor Show, Dr. Anna Cabeca sits down with renowned integrative pharmacist and thyroid expert Dr. Izabella Wentz to uncover the powerful connection between gut health, IBS, autoimmune disease, and thyroid dysfunction — especially Hashimoto's. Dr. Wentz shares her deeply personal journey from debilitating IBS, anxiety, fatigue, and Hashimoto's thyroiditis to healing through root-cause medicine. Together, Dr. Anna and Dr. Wentz explore why so many women are told their thyroid labs are "normal" while they continue struggling with weight gain, brain fog, bloating, constipation, inflammation, hormonal shifts, and exhaustion. You'll learn why gut permeability ("leaky gut"), chronic stress, infections, food sensitivities, and microbiome imbalances may be silently driving autoimmune thyroid disease — and the practical steps you can take to begin healing. In this episode, you'll discover: Why thyroid antibodies matter — even when TSH appears "normal" The hidden connection between IBS and Hashimoto's How stress hormones disrupt the gut barrier and immune system Common root causes including parasites, H. pylori, SIBO, mold, and food sensitivities The truth about bloating, constipation, diarrhea, edema, and inflammation Functional medicine testing that may uncover what conventional medicine misses Nutrition, supplements, and gut-healing strategies that can support thyroid recovery If you've ever been told "everything looks fine" while your body says otherwise, this conversation is for you. Listen now and share this episode with someone who needs answers, healing, and hope. Key Timestamps 00:00 — Why thyroid symptoms are often missed in women 04:30 — Dr. Wentz's personal journey with IBS and Hashimoto's 11:15 — The gut-autoimmune-thyroid connection explained 18:40 — Post-COVID rise in autoimmune conditions and chronic fatigue 24:50 — Functional medicine testing for IBS and thyroid symptoms 33:10 — Stress, cortisol, and "leaky gut" 41:20 — How intestinal permeability triggers autoimmune disease 49:45 — Food sensitivities, bloating, edema, and inflammation 58:30 — Gut-healing protocols and favorite supplements 01:06:20 — Why women are more prone to IBS and Hashimoto's 01:14:00 — The importance of self-advocacy and listening to your body Memorable Quotes "You may have been told your thyroid is normal, but there's something else going on — and the biggest culprit can be in the gut." — Dr. Anna Cabeca "Don't let people tell you it's all in your head." — Dr. Izabella Wentz "There will often be a disruption of the gut barrier years before an autoimmune diagnosis appears." — Dr. Izabella Wentz "To heal the human, we have to address the gut." — Dr. Anna Cabeca "Stress hormones can unlock the door to intestinal permeability and chronic inflammation." — Dr. Anna Cabeca Connect With Guest Check out Dr. Izabella's new book: IBS: Finding and Treating the Root Cause of Irritable Bowel Syndrome Instagram: https://www.instagram.com/izabellawentzpharmd/ YouTube: http://www.youtube.com/@ThyroidPharmacist Facebook: https://www.facebook.com/ThyroidLifestyle/ Website: https://thyroidpharmacist.com/ Connect With Dr. Anna Website: Dranna.com Instagram: https://www.instagram.com/thegirlfrienddoctor/ YouTube: https://www.youtube.com/@thegirlfrienddoctor TikTok: https://www.tiktok.com/@drannacabeca Facebook: https://www.facebook.com/thegirlfrienddoctor
Hey Rockstars! I have another guest with me on the podcast, Connie Nightingale! Connie is a functional health and performance coach specializing in lab interpretation, hormone balance, and total body optimization. Her approach bridges fitness, nutrition, and root-cause health, helping clients go beyond “normal” labs to truly feel their best.Some topics from today's episode include:⭐️Connie's background as a functional health and performance coach specializing in lab interpretation and hormone balance⭐️How lab ranges are based on population data and may not reflect individual health⭐️The significance of testing timing (female hormones and menstrual cycle phases) for accurate interpretation⭐️The value of monitoring trends over time for better health insights and how to spot hidden health issues using lab trends before symptoms appear⭐️The impact of lifestyle on hormone health, especially during menopause and perimenopause⭐️The dangers of overprescribed hormones and the importance of personalized HRT protocols⭐️Starting with lifestyle modifications before medication adjustments⭐️The importance of taking active participation in health—tracking, questioning providers, and understanding lab data⭐️The potential to reverse or improve health conditions through informed actions and lab insights⭐️Key panels: CBC, CMP, lipid profile, thyroid (including TSH, free T3, free T4, antibodies), sex hormones (estrogen, progesterone, FSH, LH)Join the Kickstart Round 14! Kickstart is a guided group coaching experience designed for busy, high-achieving women over 40 who are done with yo-yo dieting and ready to implement proven, sustainable methods for fat loss and strength—tailored to their individual bodies and lifestyles. https://www.rockthatfitness.com/kickstartIf you have a chance, please rate and review the podcast so more women just like you can learn more about the Rockstar way! I appreciate you for your support and love ❤️Connie's Links:Website: https://www.connienightingale.com/Instagram: https://www.instagram.com/conniebegonnie/YouTube: https://www.youtube.com/channel/UC7duTyr-etc9gaobjJC19TAFacebook: https://www.facebook.com/conniebegonnieRock That Fitness Links:⭐️Link to join Rock That Fitness Membership Today https://www.rockthatfitness.com/rock-that-fitness-membership⭐️Join the Rockstar Fit Chicks Weekly Newsletter https://rockthatfitness.kit.com/e10d0c66eb⭐️Check Out Our Exclusive Offer for Extensive Lab Work with Marek Health https://www.rockthatfitness.com/rock-that-fitness-marek-health⭐️Head to the Rock That Fitness Instagram Page https://www.instagram.com/rockthatfitness/ ⭐️Music from Uppbeat (free for Creators!):https://uppbeat.io/t/cruen/we-got-thisLicense code: RBWENWHGXSWXAEUE
The donor egg recommendation rarely comes after a complete workup. It comes after AMH, FSH, and an antral follicle count. That is usually where the investigation stops. In this episode, Sarah Clark walks through what is missing from the workup before women are told donor eggs are their only path: the full thyroid panel, not just TSH. Stool DNA testing for H. pylori, parasites, and food sensitivities. The vaginal microbiome. The male partner's blood work, which most clinics do not run. The nervous system patterns most REIs do not connect to fertility. Sarah shares Rebecca's case as a proof point. Rebecca was 27. Her AMH was 0.04 ng/mL. POI diagnosis. Told donor eggs were her only option. Her stool DNA testing revealed H. pylori and a parasite. Her food sensitivity testing showed gluten, dairy, and egg intolerance. She had adrenal insufficiency, thyroid imbalance, mineral depletion, and toxic load on her workup. Her eczema, migraines, and asthma were not separate issues. After targeted work, she conceived naturally in month five. Outcomes vary. Rebecca's case is one of many we use to illustrate what completing the workup can look like. This episode is for the woman sitting with a donor egg recommendation who is not ready to agree before she understands what was actually evaluated. The goal is clarity. Not opposition to your clinic. Not a guarantee of any outcome. Clarity on what your workup did not include, so that whatever you decide next gets made on the full picture. What this episode covers: The diagnosis is real. The investigation is incomplete. Why TSH alone is not a thyroid panel. H. pylori, hidden food sensitivities, and the gut inflammation driver. Eczema, migraines, and asthma as fertility signals. The male partner's workup should include beyond a semen analysis. Nervous system patterns most REIs do not connect to fertility. Next steps: Access the free guide: What Your Clinic Missed. The guide walks through the markers that the Fab Fertile team reviews before a donor egg recommendation. Email hello@fabfertile.ca, subject line MISSED. Book a Functional Fertility Second Opinion. We'll review your labs, your history, your full picture, and your partner's picture together, so you know what your biology has been telling you and what your next decision should be informed by. Email hello@fabfertile.ca, subject line FERTILE, or book here. About the Host I'm Sarah Clark, founder of Fab Fertile and host of Get Pregnant Naturally, a podcast with over one million downloads. My functional fertility team works with couples navigating low AMH and failed IVF, reviewing functional lab results, gut microbiome, food sensitivity, vaginal microbiome, nutrigenomics, HTMA, DUTCH, toxin testing, and bloodwork alongside nervous system work, to help identify patterns that may not have been considered. We work alongside your medical team, not instead of them. Subscribe to Get Pregnant Naturally for weekly episodes on fertility optimization, IVF preparation, and the lab work your doctor probably isn't running. Timestamps [00:00] The Donor Egg Recommendation and the Investigation Underneath It [01:00] The Diagnosis Is Real. The Investigation Is Incomplete. [02:00] Sarah's POI Story and Why Fab Fertile Exists [03:00] Rebecca's Case: POI at 27, AMH 0.04, ng/mL Told Donor Eggs Were Her Only Option [04:00] Functional Lab Testing Before a Donor Egg Decision [05:00] What We Found: H. pylori, Parasites, Food Sensitivities, Adrenal Insufficiency, Thyroid [06:00] Eczema, Migraines, Asthma: Not Separate Issues From Fertility [07:00] Rebecca Conceived Naturally in Month Five [08:00] What Your Clinic Missed: The Markers Before a Donor Egg Recommendation [09:00] Why a Standard REI Workup Cannot Answer Why Your Numbers Are What They Are [10:00] Medical Gaslighting and the Permission to Investigate Further [11:00] The Functional Fertility Second Opinion: How It Works
If you have ever been told your thyroid is "normal" while you are exhausted, gaining weight, losing hair, constipated, freezing cold, and barely making it through the day, this episode is going to hit a nerve. Because the truth is, thyroid care is still failing women in a big way. Too many doctors are only testing TSH, stopping there, and missing the full picture completely. In this episode, I sit down with my friend Dr. Amie Hornaman to talk about why thyroid treatment is still so broken, especially for women in midlife. We go into one of the most important parts of this whole conversation: advocacy. Because when it comes to thyroid health, no one is coming to save you. You have to know what to ask for, what to test, what patterns to look for, and how to push for better care. If you have been dismissed, under-treated, or told your labs are fine while your body is clearly telling a different story, this episode will give you language, clarity, and a much better understanding of what may actually be going on. In this episode, we cover: Why thyroid care has not improved nearly enough for women Why testing only TSH is not enough The thyroid labs women need to ask for What free T3, free T4, reverse T3, TPO, and Tg antibodies actually tell you Why T4-only thyroid medication often does not work well How reverse T3 can put the brakes on your metabolism Why thyroid dysfunction can affect blood sugar, insulin, fertility, and sex hormones The connection between perimenopause, menopause, and new thyroid issues Why many women are being under-medicated for hypothyroidism How to advocate for yourself and find a practitioner who actually understands thyroid care Who this episode is for This episode is for women who suspect they have a thyroid issue, have already been diagnosed with hypothyroidism or Hashimoto's, or have been told their thyroid is "fine" even though they feel anything but fine. It is especially helpful for women in perimenopause and menopause who are dealing with fatigue, weight gain, brain fog, low mood, constipation, hair loss, or feeling like their body has suddenly stopped working the way it used to. Dr. Amie Hornaman Grab a copy of Dr. Amies NEW BOOK: The Thyroid Fix: The No-Nonsense Guide to Fix Fatigue, Fogginess, and Fat That Won't Budge on Amazon Sponsors Try Mito Q Hormone and metabolic control mitoq.com/karenmartel Code: MARTEL10 Get 30% off BATCH Gummies. Go to hellobatch.com/HORMONE and use code HORMONE at checkout. Get 15% off Masszymes By BiOptimzers products at bioptimizers.com/hormone with coupon code HORMONE. Are you in perimenopause or postmenopause and struggling with symptoms—but not getting the support you deserve? At Midlife Solutions, we specialize in hormone optimization for women in midlife. Our all-female clinical team offers telehealth care across all 50 U.S. states, with the ability to prescribe bioidentical estrogen, progesterone, testosterone, and thyroid medication. Book your FREE Hormone Discovery Call Find out what's really driving your symptoms and what your next best steps are. Visit the website: https://karenmartel.com Shop the Midlife Solutions Store Over-the-counter bioidentical hormone creams and oils — no prescription needed. Including: • Progesterone • Estrogen Face Cream • Vaginal Moisturizer and more! Take the Hormone Quiz Discover hidden hormone imbalances that could be driving your symptoms. Get personalized results (and yes, they may surprise you). Women's Peptide Weight Loss Program Clinically guided, hormone-aware weight loss for midlife women. Midlife RESET HRT Program A complete, supportive approach to hormone replacement therapy in midlife. Your host: Karen Martel Certified Hormone Specialist, Transformational Nutrition Coach, & Weight Loss Expert Karen's Facebook Karen's Instagram
Diagnosis, workup, and the four-step treatment protocol for thyroid storm. Hosts: Annaliese Elam, MD Brian Gilberti, MD https://media.blubrry.com/coreem/content.blubrry.com/coreem/Thyroid_Storm.mp3 Download Leave a Comment Tags: Critica Care, Endocrine, Thyroid Storm Show Notes I. Pathophysiology & Diagnosis Definition: Life-threatening hypermetabolic state resulting from decompensated thyrotoxicosis. Hormonal Profile: Absolute levels of total T₄/T₃ often mirror uncomplicated thyrotoxicosis; storm is driven by rapid rate of rise, increased catecholamine sensitivity, or increased free T₄/T₃ concentrations. Clinical Presentation: Hyperpyrexia (e.g., 104.2°F) Tachycardia/Arrhythmias (e.g., 155 bpm) Altered Mentation: Agitation, delirium, or psychosis; often the primary differentiator between “storm” and “compensated” hyperthyroidism Warm, moist skin Precipitating Events: Infection, trauma, or surgery Parturition Abrupt cessation of antithyroid medications Burch-Wartofsky Point Scale (BWPS): ≥ 45: Highly suggestive of Thyroid Storm 25–44: Suggestive of impending storm < 25: Storm unlikely Note: High sensitivity but low specificity; can be skewed by unrelated febrile illness. II. Laboratory & Ancillary Findings Thyroid Panel: Characteristically low TSH with elevated free T₄ and T₃. Metabolic Abnormalities: Mild hyperglycemia (catecholamine-induced insulin inhibition) Mild hypercalcemia Elevated LFTs and leukocytosis Cardiovascular: EKG may show sinus tachycardia or atrial fibrillation with rapid ventricular response. III. Management: The Four-Step Blocking Strategy Step 1: Sympathetic Blockade (Beta Blockers) Agent of Choice: Propranolol Mechanism: Non-selective blockade; in high doses, inhibits peripheral conversion of T₄ to T₃. Dosing: PO: 60–80 mg every 4–6 hours IV: 0.5–1 mg over 10 minutes Critical Pitfall: Avoid in patients with acute decompensated heart failure with systolic dysfunction; risk of cardiovascular collapse. Step 2: Inhibition of Hormone Synthesis (Thionamides) Agent of Choice: Propylthiouracil (PTU) preferred over Methimazole in life-threatening storm. Mechanism: Blocks synthesis of new hormone and inhibits peripheral T₄-to-T₃ conversion (decreases T₃ by ~45% in 24 hours). Dosing: 200–250 mg PO every 4 hours Step 3: Inhibition of Hormone Release (Iodine) Agents: Potassium iodide (SSKI) or Lugol’s solution Critical Timing: Must wait at least 60 minutes AFTER thionamide administration. Rationale: Immediate iodine administration provides substrate for new hormone synthesis (Wolff-Chaikoff effect bypass), potentially worsening thyrotoxicosis. Step 4: Inhibition of Peripheral Conversion & Adrenal Support Agent: Glucocorticoids (Hydrocortisone) Mechanism: Inhibits peripheral T₄ to T₃ conversion and treats potential relative adrenal insufficiency. Dosing: 300 mg IV loading dose, followed by 100 mg IV every 8 hours IV. Supportive Care & Avoidance Measures Hyperpyrexia Management: Acetaminophen is the standard of care Avoid Aspirin: Salicylates displace thyroid hormone from thyroid-binding globulin (TBG), increasing free T₄/T₃ levels Volume Resuscitation: Aggressive IV fluids; patients are often profoundly dehydrated May require 3–5 liters of isotonic crystalloid per 24 hours Take Home Points I. Diagnostic Essentials Clinical Diagnosis: Based on hyperpyrexia, cardiovascular dysfunction, and altered mentation. Key Differentiator: Altered mentation (agitation, delirium, psychosis) is often the sole finding distinguishing “storm” from “compensated” thyrotoxicosis. Burch-Wartofsky Point Scale (BWPS): ≥ 45: Highly suggestive of storm. 25–44: Suggests impending storm. < 25: Storm unlikely. Note: High sensitivity, low specificity (e.g., hyperthyroid + flu can score > 45). Triggers: Infection, trauma, parturition, or abrupt cessation of antithyroid drugs. II. The Four-Step Blocking Strategy Beta Blockade (Propranolol): Dose: 60–80 mg PO q4–6h or 0.5–1 mg IV over 10 min. Action: Blocks symptoms and inhibits peripheral T4 to T3 conversion. Caution: Avoid in acute decompensated heart failure with systolic dysfunction. Thionamides (PTU): Dose: 200 to 250 mg every four hours. (note: some resources suggest a loading dose beforehand) Action: Preferred over methimazole; blocks new hormone synthesis and peripheral T4 to T3 conversion. Iodine (SSKI/Lugol’s): Timing: Must wait ≥ 60 minutes AFTER thionamide dose. Action: Blocks hormone release. Pitfall: Early iodine provides substrate for new hormone synthesis, worsening the condition. Glucocorticoids (Hydrocortisone): Dose: 300 mg IV load, then 100 mg IV q8h. Action: Blocks conversion and provides adrenal support. III. Critical Supportive Care Hyperpyrexia: Use Acetaminophen. NEVER Use Aspirin: Displaces thyroid hormone from binding proteins, acutely increasing free T4/T3 levels. Volume: Aggressive fluid resuscitation; patients may require 3–5 L/day due to profound dehydration. Read More
Are you doing "all the right things" but still gaining weight, losing hair, feeling exhausted, foggy, anxious, or stuck in your body? Your thyroid may be the missing piece. In this powerful episode of The Girlfriend Doctor Podcast, Dr. Anna Cabeca welcomes Dr. Amie Hornaman—also known as "The Thyroid Fixer," founder of the Advanced Thyroid and Hormone Clinic, host of The Thyroid Fixer podcast, and author of The Thyroid Fix: The No Nonsense Guide to Fix Fatigue, Fogginess and Fat That Won't Budge. Together, Dr. Anna and Dr. Amie unpack why thyroid dysfunction is so often missed in perimenopause and menopause—and why a "normal" TSH may not tell the whole story. They discuss Hashimoto's, weight-loss resistance, hair loss, fatigue, iodine, T2, reverse T3, thyroid antibodies, hormone shifts, stress, environmental toxins, and why women must advocate for a complete thyroid panel. In this episode, you'll learn: Why fatigue, hair loss, depression, constipation, cold intolerance, and stubborn belly fat may point to thyroid dysfunction The full thyroid panel Dr. Amie recommends beyond TSH How perimenopause and menopause can trigger or worsen Hashimoto's Why T4-only medication may not work for every woman The role of iodine, selenium, magnesium, vitamin D, black cumin seed oil, and T2 Why thyroid optimization is a longevity strategy—not just a weight-loss conversation Dr. Amie also shares her personal journey of misdiagnosis, thyroid recovery, PCOS, and navigating endometrial cancer with courage, honesty, and functional medicine wisdom. Listen now and remember: you are your best health advocate—and there is always one next right step. Key Timestamps 00:00 — Why thyroid symptoms often show up in menopause 04:20 — The top symptoms of thyroid dysfunction 08:30 — Hashimoto's, autoimmunity, and hormone shifts 16:40 — The full thyroid panel every woman should know 27:00 — Iodine, thyroid antibodies, and detox reactions 36:30 — Dr. Amie's personal thyroid misdiagnosis story 46:00 — Thyroid dysfunction and weight-loss resistance 55:00 — Optimizing thyroid hormones at every age 1:04:00 — PCOS, progesterone, and endometrial cancer 1:14:00 — T2, metabolism, and mitochondrial support Memorable Quotes "From head to toe, the thyroid runs the show." — Dr. Amie Hornaman "Women are being dismissed when it really is a thyroid problem that can be treated." — Dr. Amie Hornaman "We don't want normal. We want optimal." — Dr. Anna Cabeca "The thyroid is a longevity optimizer, not just an aesthetics conversation." — Dr. Amie Hornaman "You are your best advocate for your health." — Dr. Anna Cabeca Connect With Dr. Amie Hornaman Book: The Thyroid Fix: https://www.simonandschuster.com/books/The-Thyroid-Fix/Dr-Amie-Hornaman/9781668225424 Website: https://dramie.com Supplements: https://betterlifedoctor.com/annacabeca Use code: DRANNA for 10% off Instagram: https://www.instagram.com/dramiehornaman/ YouTube: youtube.com/@DrAmieHornaman Facebook: https://www.facebook.com/AmieHornaman Connect With Dr. Anna Cabeca Website: https://dranna.com Instagram: https://www.instagram.com/thegirlfrienddoctor/ YouTube: https://www.youtube.com/@thegirlfrienddoctor TikTok: https://www.tiktok.com/@drannacabeca Facebook: https://www.facebook.com/thegirlfrienddoctor
Leveling Up: Creating Everything From Nothing with Natalie Jill
Save your seat in the free Thyroid and Hormone class https://fixyourthyroid.com/natalie If you are a woman in midlife who has been told everything is fine when you know in your body that something is NOT fine, this episode is going to change everything. I have Dr. Amie Hornaman, The Thyroid Fixer, back on the show, and we are going somewhere we have never gone before. One in eight women will develop a thyroid condition in her lifetime. Eighty-eight percent of us are metabolically unhealthy. And yet most doctors run ONE test, look at one number, tell us we are normal, and send us home with an antidepressant. Meanwhile we are gaining weight, losing our hair, can't sleep, can't think, can't lose a pound to save our lives, and being told it is just stress, just aging, just menopause. Today we are tearing that apart. Dr. Amie saw SEVEN doctors before she was finally diagnosed. She is now licensed to prescribe thyroid and bioidentical hormones in all 50 states and most of Canada. She built the Better Thyroid and Hormone Institute, hosts The Thyroid (and Hormone) Fixer Podcast, and has helped thousands of women globally finally get answers. We go DEEP on: Why the standard TSH-only test misses almost everyone, and the six tests you need to ask for by name THYROPAUSE: Dr. Amie's term for what happens when thyroid dysfunction collides with perimenopause and menopause (and why so many women are being treated for the wrong one) The T4-only medication trap: why Synthroid and levothyroxine fail an estimated 98% of patients Reverse T3, the silent saboteur that blocks your active thyroid hormone from getting into your cells Natural desiccated thyroid, the controversy, FDA scrutiny of animal-derived medications, and where Dr. Amie stands T2: the FORGOTTEN thyroid hormone with 30+ years of research that burns fat at the mitochondrial level, does not suppress your own thyroid, does not jack up your heart rate, does not require a prescription, and is showing up in studies as a potential anti-obesity treatment What Ozempic, Wegovy, and Mounjaro are actually doing to your thyroid (and why some women lose ZERO weight on GLP-1s no matter how high they push the dose) The estrogen, progesterone, testosterone, cortisol, and insulin connection: why you cannot fix the thyroid without addressing the whole hormonal system Antibody-support strategies: gluten elimination, black cumin seed oil, low-dose naltrexone, and thymosin alpha Iodine titration cautions, medical gaslighting, and what to say when your doctor refuses to run the full panel The Monday morning action plan: exactly what to do this week if you suspect your thyroid is the missing piece This is not a thyroid 101 episode. This is the conversation I wish every midlife woman was given the day her labs came back normal. You are not broken. You are not crazy. And you are not alone. Sign up for the free Thyroid and Hormone class https://fixyourthyroid.com/natalie Connect with Dr. Amie: Podcast: The Thyroid (and Hormone) Fixer Instagram: @dramiehornaman Book: https://thyroidfixbook.com/ Live lab-review class https://fixyourthyroid.com/natalie Better Thyroid and Hormone Institute: dramiehornaman.com APPROXIMATE TIMESTAMPS: 00:00 — The medical gaslighting that is keeping midlife women sick 06:00 — The full thyroid panel: the six tests to ask for by name 12:00 — Introducing THYROPAUSE: where thyroid meets menopause 20:00 — How estrogen, progesterone, testosterone, and cortisol all impact your thyroid 28:00 — Why T4-only medication (Synthroid, levothyroxine) fails 98% of patients 34:00 — Natural desiccated thyroid, FDA scrutiny, and individualized dosing 40:00 — T2: the forgotten thyroid hormone that burns fat without touching your gland 48:00 — Who should consider T2 (and why it does not require a prescription) 52:00 — What Ozempic and the GLP-1s are actually doing to your thyroid 58:00 — How to protect your thyroid if you are currently on a GLP-1 62:00 — Lifestyle non-negotiables: morning sun, protein, resistance training, sleep, blood sugar 67:00 — Your Monday morning action plan if you suspect your thyroid is the missing piece Catch the full episode on YOUTUBE HERE: https://bit.ly/MidlifeConversationsYouTube Learn More About Dr. Amie Hornaman Instagram ➜ https://www.instagram.com/dramiehornaman Website ➜ https://fixyourthyroid.com/natalie Thank you to our show sponsors: MITOQ: Take control of healthy aging and longevity. Get 10% off using code NATALIEJILL at checkout on https://www.mitoq.com/ BIOPTIMIZERS: Get the digestive enzymes I take with every meal here https://www.bioptimizers.com/nataliejill Free Gifts for being a listener of Midlife Conversations! Mastering the Midlife Midsection Guide: https://theflatbellyguide.com/ Age Optimizing and Supplement Guide: https://ageoptimizer.com Connect with me on social media! Instagram: www.Instagram.com/Nataliejllfit Facebook: www.Facebook.com/Nataliejillfit For advertising inquiries: https://www.category3.ca/ Disclaimer: Information provided in the Midlife Conversations podcast is for informational purposes only. This information is NOT intended as a substitute for the advice provided by your physician or other healthcare professional. Do not use the information provided in this podcast for diagnosing or treating a health problem or disease, or prescribing medication or other treatment. Always speak with your physician or other healthcare professional before making any changes to your current regimen. Information provided in this podcast and the use of any products or services related to this podcast does not create a client-patient relationship between you and the host of Midlife Conversations or you and any doctor or provider interviewed and featured on this show. Information and statements may have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent ANY disease. Advertising Disclosure: Some episodes of Midlife Conversations may be sponsored by products or services discussed during the show. The host may receive compensation for such advertisements or if you purchase products through affiliate links. Opinions expressed about products or services are those of the host and/or guests and do not necessarily reflect the views of any sponsor. Sponsorship does not imply endorsement of any product or service by healthcare professionals featured on this podcast.
Today, I'm joined by the incredible Dr. Amie Hornaman, a leading thyroid expert and author of the brand new book, The Thyroid Fix. In our conversation, Dr. Hornaman opens up about her personal struggle with undiagnosed thyroid disease—a journey marked by frustrating medical gaslighting and the dismissive “you're normal” diagnoses from doctor after doctor. She reveals how that experience led her to become a passionate advocate for women (and men) suffering from thyroid dysfunction and a pioneer in holistic, root-cause approaches to healing. Episode Timestamps: Introduction and show purpose ... 00:00:00 Dr. Hornaman's personal story and medical gaslighting ... 00:05:05 Journey to functional medicine and importance of symptom-based care ... 00:11:00 Recognizing key thyroid-related symptoms ... 00:14:51 Wearables and tracking thyroid-related trends ... 00:17:18 Understanding thyropause and hormone fluctuations after 40 ... 00:19:31 Impact of thyroid function on overall longevity and health ... 00:23:43 T4-only medication debate and need for personalized treatment ... 00:36:19 Why T4-only persists in conventional practice ... 00:40:40 T2, metabolism, mitochondrial health, and iodine ... 00:45:21 GLP-1 medications, thyroid optimization, and weight loss stories ... 00:50:16 Personalization of thyroid numbers and treatment ... 00:53:46 Functional versus conventional thyroid lab ranges ... 00:54:59 Thyroid's connection to mood and mental health ... 00:56:42 When lifestyle alone can't restore thyroid health ... 00:58:39 Biggest myth: TSH and T4-only standard of care ... 01:07:59 Our Amazing Sponsors: O₃RACLE by Wizard Sciences — A daily ozonated oil capsule designed to support immune balance, cellular communication, and antioxidant production without clinics, machines, or complicated routines; learn more at wizardsciences.com and use code NAT15 for 15% off. Quantum Upgrade - Supports nervous system balance without wearables or apps—just effortless, 24/7 quantum energy streaming. With 21+ studies showing measurable improvements in stress and cellular function, it's easy to try for yourself. Visit quantumupgrade.io/NAT and use code NAT15 to start the free 15 day trial. MassZymes by BiOptimizers – A full-spectrum digestive enzyme formula with 4x more protease to help break down protein into usable amino acids so your body actually benefits from what you eat—try it risk-free with a 365-day money-back guarantee and save 15% at bioptimizers.com/bionat with code BIONAT. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Dr. Bill Lawrence Episode
In this powerful episode, Dr. Fiona Lovely welcomes back her friend and colleague, Dr. Amie Hornaman—known globally as "The Thyroid Fixer." Dr. Amie is a functional medicine expert, host of the top-rated The Thyroid Fixer podcast, and author of the new book The Thyroid Fix: The No-Nonsense Guide to Reclaiming Your Health. Together, they pull back the curtain on why conventional medicine continues to fail women when it comes to thyroid and hormone health. Dr. Amie shares her journey of being misdiagnosed and how that fueled her mission to help women stop wishing on a rainbow for their health to improve. She explains why relying solely on TSH and T4 is a dangerous gamble, revealing that the real story lies in free T3 and reverse T3. Listeners will learn why T4-only medication like Synthroid often falls short and how to advocate for proper testing and treatment. The conversation also explores the forgotten thyroid hormone T2, its role in burning fat without losing muscle, and how GLP-1 medications intersect with thyroid function. Dr. Amie provides scripted, respectful language for women to use with their doctors, including a powerful "nuclear option" to ensure their concerns are documented. Episode Highlights: Why TSH is a misleading marker and which two tests truly matter for thyroid health. The problem with T4-only medication and why it can backfire. How to approach your doctor without overwhelming them—three bullet points, no life stories. The fascinating role of T2 in metabolism and weight loss. A candid discussion on thyroid nodules, unnecessary surgeries, and patient advocacy. Tune in to learn how to become the CEO of your own health, because waiting for your doctor to catch up is no longer an option. Thank you to our sponsors for this episode: Women in perimenopause and menopause talk about wanting the same things — less bloating, no afternoon crash after eating, steady energy. MassZymes is perfect for helping your body's ability to actually process what you eat. MassZymes uses a full-spectrum blend of 18 enzymes. That means you're getting more out of the food you eat. Plus, it works across different stomach acid levels, which can really matter as we age. Here's what you get when you go to bioptimizers.com/lovely and use code LOVELY: 15% off your entire order AND a free bottle of Masszymes — BiOptimizers' best-selling digestive enzyme — added to your order automatically when you use our exclusive code.
What are the experts saying about thyroid cancer treatment in 2025? Maybe it's time to discuss deescalation of aggressive surgical care for lower risk thyroid cancers. We can accept that less surgery may be appropriate in select cases, including more thyroid lobectomies versus total thyroidectomies, consider less invasive approaches such as percutaneous ablation techniques, and utilize more observation with active surveillance. Early assessment of treatment may allow appropriate reduction in use of radioactive iodine ablation and more relaxed routine monitoring can reduce surveillance burden to patients and providers. Hosts: - Amanda Doubleday, DO, MBA, Assistant Professor, Waukesha Surgical Specialists, ProHealth Care. Affiliated with University of Wisconsin School of Medicine and Public Health, Department of Surgery. - Simon Holoubek, DO, MPH, Assistant Professor, University of Wisconsin School of Medicine and Public Health, Department of Surgery. - Alexander Chiu, MD, Assistant Professor, University of Wisconsin School of Medicine and Public Health, Department of Surgery. - Rebecca S Sippel, MD, FACS, Professor and Chair of Division of Endocrine Surgery, Vice Chair of Academic Affairs and Professional Development, University of Wisconsin School of Medicine and Public Health, Department of Surgery. Learning Objectives:- Risk stratification system now includes 4 categories: low, low-intermediate, high-intermediate, and high-TSH suppression targets are simplified: below the normal range if there is structural or biochemical disease and in the normal range if disease free. - Thyroid lobectomy is recommended for tumors < 2cm cT1N0 tumors and can be considered for tumors 2-4 cm. - Micro-Papillary Thyroid Carcinoma (
Could your "thyroid problem" actually be an underlying autoimmune condition that is currently being ignored? I sat down with Dr. Heather Stone, a practitioner dedicated to uncovering what's really going on when your labs say you're "fine" but you feel anything but. We dive deep into why the vast majority of thyroid cases are actually Hashimoto's and how environmental triggers like gluten and glyphosate are fueling the fire. You'll learn how to stop being "patted on the head" by conventional medicine and start taking control of your hormones and immune health through comprehensive testing. (00:00) A "normal" TSH range doesn't always mean your thyroid health is functioning optimally. (00:52) Common symptoms of thyroid issues that are frequently dismissed as simple aging or perimenopause. (02:05) The majority of women diagnosed with low thyroid actually have an underlying autoimmune condition called Hashimoto's. (03:33) Shift your focus from the thyroid as the victim to the underlying immune system triggers causing the attack. (04:05) The feedback loops between insulin surges and immune system attacks on your thyroid. (05:56) The specific 12 markers needed for a comprehensive dysglycemia panel to truly assess your metabolic health. (06:39) Two specific antibodies are required to accurately diagnose Hashimoto's disease beyond standard lab tests. (08:21) Gluten sensitivity and glyphosate exposure are significant factors in thyroid-related molecular mimicry. Watch the full episode:https://youtu.be/l-f7xXIn2cw?si=kznm8Jjd5QfQVkfg Full show notes (including all links mentioned): https://jjvirgin.com/drheather Learn more about your ad choices. Visit megaphone.fm/adchoices
Real Life Pharmacology - Pharmacology Education for Health Care Professionals
This podcast episode gives nurses a practical, easy-to-apply overview of common thyroid disorders, focusing on how to recognize and manage both hypothyroidism and hyperthyroidism in clinical practice. It reviews key differences in presentation—such as fatigue, weight gain, and cold intolerance in hypothyroidism versus weight loss, tachycardia, and heat intolerance in hyperthyroidism—while connecting these symptoms to underlying physiology. Nurses will learn important medication considerations, including proper administration of levothyroxine and monitoring for adverse effects with methimazole. The episode also highlights critical safety topics like recognizing thyroid storm, interpreting lab values (TSH, T3, T4), and providing effective patient education. With real-world clinical pearls, this episode helps nurses build confidence in managing thyroid conditions across care settings. Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!