Podcasts about brain inflammation

In this episode of the Root Cause Medicine Podcast, Dr. Kate Kresge sits down with functional immunology expert and educator Dr. Samuel Yanuck to explore one of the most overlooked systems in chronic illness: the immune system. With clarity and compassion, Dr. Yanuck breaks down how immune dysregulation can contribute to complex conditions like depression, neuropathy, migraines, chronic fatigue, and even cardiovascular disease. From brain inflammation and mast cell activation to Epstein-Barr virus and mold, Dr. Yanuck offers a new way of thinking about biology—where inflammation isn't just a symptom, but a system that can be measured, understood, and treated. You'll here them discuss: - Why immunology could be at the root of nearly every chronic illness - The immune pathways that connect depression, anxiety, brain fog, and fatigue - What PANS, PANDAS, and autoimmune encephalitis really are—and why they're often misdiagnosed - How gut, brain, and immune health form a feedback loop - The labs you should run if you suspect chronic immune dysfunction - A framework for evaluating chronic viral infections like EBV and CMV - Natural immune modulators: Chinese skullcap, astragalus, quercetin, sulforaphane, and more - Why personalized immune workups—not protocols—create results Guest Bio: Dr. Samuel Yanuck is a functional medicine clinician and expert educator in functional immunology. He is the creator of Cogence Immunology, a comprehensive online training program that has educated over 9,000 clinicians in over 60 countries. His approach blends immunology, clinical experience, and systems thinking to help providers and patients uncover the true drivers of chronic illness. Dr. Yanuck is also the co-founder of the Yanuck Center for Life and Health in North Carolina, where he sees patients and helps clinicians find root-cause solutions to immune dysfunction through mentorship and collaboration. His work is helping reshape how the next generation of practitioners understand inflammation, autoimmunity, and healing. Order tests through Rupa Health, the BEST place to order functional medicine lab tests from 30+ labs - https://www.rupahealth.com/reference-guide

Did you know that it's impossible to have gut issues without feeling grief and regret, and equally impossible to hold grief while maintaining a healthy gut?  In this mini-episode, Dr. Aimie explores the powerful connection between constipation and grief, expanding on her discussion in Episode 124. She answers a listener's question about remaining stuck in grief work despite months of therapy, and how chronic constipation might be the  barrier preventing emotional healing. You'll hear more on: How grief triggers a biological trauma response that directly impacts digestion The effect constipation has on your nervous system How constipation leads to brain inflammation, mental fatigue, and emotional shutdown Why your gut health directly impacts your ability to process emotions Practical strategies to improve your constipation  Why talk therapy alone may not be enough when the nervous system is stuck in overwhelm If you're struggling with both grief and digestive issues, or if you're a practitioner working with clients who seem stuck in their healing journey, this episode offers crucial insights into the biological barriers that may be preventing progress. To hear the full episode and access additional resources, head over to Episode 124: Grief and Gut Health to learn more!  

Dr. Jordan Vaughn estimates 15M Americans face long COVID or vaccine injuries, with the SARS-CoV-2 spike protein causing symptoms like brain fog, strokes, and – according to a new paper in the “Brain, Behavior, and Immunity” medical journal – even neuroinflammation in “brain regions relevant to Parkinson's disease.” Dr. Nicole Saphier, a board-certified radiologist with fellowship training in breast and oncologic imaging, is a NYT best-selling author and host of Wellness Unmasked on iHeartRadio. She authored Panic Attack: Playing Politics with Science in the Fight Against COVID-19 and the children's book That's What Family's For. More at https://x.com/nbsaphierMD and https://nicolesaphiermd.com Dr. Jordan F. Vaughn, a physician and clinical researcher, is a Diplomate of the American Board of Internal Medicine and Founder of The Microvascular Research Foundation. He focuses on microvascular health and vaccine-related injuries. More at https://x.com/jfvaughnmd09 and https://mvresearch.org 「 SUPPORT OUR SPONSORS 」 Find out more about the brands that make this show possible and get special discounts on Dr. Drew's favorite products at ⁠⁠⁠⁠⁠https://drdrew.com/sponsors⁠⁠⁠⁠⁠  ⁠⁠⁠⁠⁠⁠⁠⁠⁠ • ACTIVE SKIN REPAIR - Repair skin faster with more of the molecule your body creates naturally! Hypochlorous (HOCl) is produced by white blood cells to support healing – and no sting. Get 20% off at ⁠⁠⁠⁠⁠https://drdrew.com/skinrepair⁠⁠⁠⁠⁠ • FATTY15 – The future of essential fatty acids is here! Strengthen your cells against age-related breakdown with Fatty15. Get 15% off a 90-day Starter Kit Subscription at ⁠⁠⁠⁠⁠https://drdrew.com/fatty15⁠⁠⁠⁠⁠ • PALEOVALLEY - "Paleovalley has a wide variety of extraordinary products that are both healthful and delicious,” says Dr. Drew. "I am a huge fan of this brand and know you'll love it too!” Get 15% off your first order at ⁠⁠⁠⁠⁠https://drdrew.com/paleovalley⁠⁠⁠⁠⁠ • THE WELLNESS COMPANY - Counteract harmful spike proteins with TWC's Signature Series Spike Support Formula containing nattokinase and selenium. Learn more about TWC's supplements at ⁠⁠⁠⁠⁠https://twc.health/drew⁠⁠⁠⁠⁠ 「 MEDICAL NOTE 」 Portions of this program may examine countervailing views on important medical issues. Always consult your physician before making any decisions about your health. 「 ABOUT THE SHOW 」 Ask Dr. Drew is produced by Kaleb Nation (⁠⁠⁠⁠⁠https://kalebnation.com⁠⁠⁠⁠⁠) and Susan Pinsky (⁠⁠⁠⁠⁠https://twitter.com/firstladyoflov⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠e⁠⁠⁠⁠⁠). This show is for entertainment and/or informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment. Learn more about your ad choices. Visit megaphone.fm/adchoices

Did you know that, according to research, only 50% of people experience relief from antidepressants? Why could this be? In this mini-episode, Dr. Aimie explores why antidepressants often fail to provide relief for many people, expanding on her discussion in Episode 120. She answers a listener's question about what may be causing her to continue to experience brain fog and feeling flat despite increased medication dosage. You'll hear more on: What is really driving the mental health epidemic The five steps of how the body experiences a trauma response The missing piece in depression treatment (it's NOT what you think!) How stored trauma and persistent depression symptoms are connected What can create brain inflammation How lifestyle factors like poor sleep can trigger the same response as emotional trauma If you're taking antidepressants but still struggling with symptoms, this episode offers a deeper understanding of the underlying biology and practical strategies to address brain inflammation for more effective healing. To hear the full episode and grab the links Dr. Aimie mentioned, head over to Episode 120: Why Antidepressants Don't Work for Everyone to find out more!  

Brain fog isn't just a brain issue...     It's often the result of inflammation triggered in the body.     On today's episode, I'll break down what may be contributing to that inflammation—ultimately leading to symptoms like forgetfulness, lack of focus, mental fuzziness, and reduced clarity of thought.     Join me on today's Cabral Concept 3371, where we go over the 6 toxins that can lead to brain inflammation and eventually brain fog. Enjoy the show, and let me know your thoughts!   - - - For Everything Mentioned In Today's Show: StephenCabral.com/3371 - - - Get a FREE Copy of Dr. Cabral's Book: The Rain Barrel Effect - - - Join the Community & Get Your Questions Answered: CabralSupportGroup.com - - - Dr. Cabral's Most Popular At-Home Lab Tests: > Complete Minerals & Metals Test (Test for mineral imbalances & heavy metal toxicity) - - - > Complete Candida, Metabolic & Vitamins Test (Test for 75 biomarkers including yeast & bacterial gut overgrowth, as well as vitamin levels) - - - > Complete Stress, Mood & Metabolism Test (Discover your complete thyroid, adrenal, hormone, vitamin D & insulin levels) - - - > Complete Food Sensitivity Test (Find out your hidden food sensitivities) - - - > Complete Omega-3 & Inflammation Test (Discover your levels of inflammation related to your omega-6 to omega-3 levels) - - - Get Your Question Answered On An Upcoming HouseCall: StephenCabral.com/askcabral - - - Would You Take 30 Seconds To Rate & Review The Cabral Concept? The best way to help me spread our mission of true natural health is to pass on the good word, and I read and appreciate every review!  

Nutritionist Leyla Muedin details the impact of chronic stress on the brain, explaining how stress can lead to cognitive decline, weakened memory, impaired focus, and increased emotional reactivity. Leyla highlights the critical roles played by the hippocampus, prefrontal cortex, and amygdala in stress responses. Furthermore, she explores dietary choices that can help mitigate these negative effects, emphasizing foods rich in Omega-3 fatty acids, antioxidants, and magnesium, while cautioning against sugar, refined carbs, and excessive caffeine or alcohol consumption. Leyla advises on the importance of balanced nutrition in fostering brain resilience and reversing stress-induced damage.

Dr. Tony Ebel interviews Dr. David Jockers, a renowned expert in functional nutrition. Dr. Jockers shares in-depth insights about the critical connection between blood sugar stability and nervous system health, particularly in children. Drawing from his personal experiences and extensive clinical work, he explains how proper nutrition can transform brain function, behavior, and overall wellbeing. The conversation covers practical strategies for parents to implement, from protein prioritization to hydration tips, and explores how modeling healthy behaviors creates lasting change for children. This episode provides actionable nutrition advice that can truly move the needle for families dealing with chronic health challenges.[00:06:00] Blood Sugar StabilityDr. Jockers identifies blood sugar stability as a major "needle mover" for healthPersonal story of growing up with blood sugar crashesWhy seed oils are problematic for cellular health[00:12:00] Protein Priorities for ChildrenGuidance on protein intake and why protein should be consumed first in a mealHow protein intake stabilizes blood sugar and prevents crashes[00:16:00] The Neuroscience of Blood SugarConnection between nervous system stability and blood sugar stabilityThe difference between hyperglycemia and reactive hypoglycemia in childrenHow hypoglycemic episodes damage neurons and increase risk of neurodegeneration[00:21:00] POTS Syndrome and Blood Sugar ConnectionDiscussion of how blood sugar instability contributes to POTS syndromeThe cascade effect: blood sugar instability → nervous system instability → hormonal instabilityDr. Ebel's clinical observations with teenage and young adult patients[00:25:00] Optimizing Brain Function Through NutritionHow stable blood sugar increases BDNF (Brain-Derived Neurotrophic Factor)Benefits of BDNF: creativity, innovation, better connections between neuronsPractical meal structure and "eating the rainbow" for phytonutrients[00:30:00] Hydration and Supplementation StrategiesThe importance of hydration timing (away from meals)Electrolytes and minerals: benefits for kids, especially active onesSupplements vs. food: "90% of health results come from lifestyle"Key supplements that make a difference: Magnesium, Vitamin D, K2[00:36:00] Modeling Health for ChildrenThe importance of parents demonstrating healthy behaviorsTeaching children nutritional concepts through benefit-focused languageConnect with Dr. Jockers: Website: www.drjockers.comInstagram: @drjockersYoutube: @drdavidjockers-- DETAILS & REGISTRATION FOR THE FREE MAY AUTISM SUMMIT Follow us on Socials: Instagram: @pxdocs Facebook: Dr. Tony Ebel & The PX Docs Network Youtube: The PX Docs For more information, visit PXDocs.com to read informative articles about the power of Neurologically-Focused Chiropractic Care. Find a PX Doc Office near me: PX DOCS DirectoryTo watch Dr. Tony's 30 min Perfect Storm Webinar: Click HereSubscribe, share, and stay tuned for more incredible episodes unpacking the power of Nervous System focused care for children!

In today's episode of The Root Cause Medicine Podcast, Dr. Carrie Jones sits down with Dr. Kellyann Niotis to discuss brain health and neurodegeneration prevention. What You'll Learn: 1. Why brain health should be a priority starting in early adulthood 2. How neurodegenerative diseases begin decades before symptoms appear 3. The role of lifestyle factors in maintaining brain health 4. New blood-based biomarkers and traditional imaging methods 5. The relationship between hormones and brain health Dr. Kellyann Niotis is the first and only fellowship-trained preventive neurologist specializing in early detection and prevention of neurodegenerative diseases. As a leading expert in brain health and preventative neurology, she brings extensive experience in movement disorders and Parkinson's disease to her practice. Through her work at the Institute for Neurodegenerative Diseases in Florida, Dr. Niotis focuses on identifying and addressing neurological health concerns decades before symptoms appear. She is dedicated to transforming how we approach brain health, combining cutting-edge diagnostics with personalized prevention strategies. Order tests through Rupa Health, the BEST place to order functional medicine lab tests from 30+ labs - https://www.rupahealth.com/reference-guide

In this fascinating and highly anticipated episode, we sit down with Anthony William—better known as the Medical Medium—the man behind the global celery juice movement, Brain Shot Therapy, and a wave of viral wellness revelations. A #1 New York Times best-selling author and chronic illness expert, Anthony has spent his life sharing advanced healing insights he receives from the Spirit of Compassion—insights that have transformed the lives of millions, including celebrities, athletes, and those suffering from mysterious, unresolved conditions. We dive deep into his extraordinary gift, his early experiences channeling medical information, and his most powerful discoveries around brain health, chronic inflammation, life-changing foods, and how to truly cleanse and heal. Whether you're a skeptic or a believer, this episode just might change the way you think about your health. Mentioned in the Episode: Medical Medium's Website Medical Medium's Recipes The Medical Medium Podcast Medical Medium Brain Saver: Answers to Brain Inflammation, Mental Health, OCD, Brain Fog, Neurological Symptoms, Addiction, Anxiety, Depression, Heavy Metals, Epstein-Barr Virus by A.W. Medical Medium Brain Saver Protocols, Cleanses & Recipes: For Neurological, Autoimmune & Mental Health by A.W. Medical Medium Cleanse to Heal: Healing Plans for Sufferers of Anxiety, Depression, Acne, Eczema, Lyme, Gut Problems, Brain Fog, Weight Issues, Migraines, Bloating, Vertigo, Psoriasis by A.W. Medical Medium Celery Juice: The Most Powerful Medicine of Our Time Healing Millions Worldwide by A.W. Medical Medium Liver Rescue: Answers to Eczema, Psoriasis, Diabetes, Strep, Acne, Gout, Bloating, Gallstones, Adrenal Stress, Fatigue, Fatty Liver, Weight Issues, SIBO & Autoimmune Disease by A.W Medical Medium Thyroid Healing: The Truth behind Hashimoto's, Graves', Insomnia, Hypothyroidism, Thyroid Nodules & Epstein-Barr by A.W. Medical Medium Life-Changing Foods: Save Yourself and the Ones You Love with the Hidden Healing Powers of Fruits & Vegetables by A.W Medical Medium: Secrets Behind Chronic and Mystery Illness and How to Finally Heal (Revised and Expanded Edition) by A.W. Barley Grass Juice Powder Spirulina Dulse Seaweed  MSM & Silica+Calcium Vitamin C A Sony Music Entertainment production. Find more great podcasts from Sony Music Entertainment at sonymusic.com/podcasts and follow us at @sonypodcasts To bring your brand to life in this podcast, email podcastadsale Learn more about your ad choices. Visit podcastchoices.com/adchoices

Warning: Watching this episode may cause side effects like laughing, learning, and discovering unseen stress bears!

Today, I have the privilege of speaking with Dr. Drew Ramsey, a board-certified psychiatrist, author, and a leading voice in nutritional psychiatry and integrative mental health.  With over 50 million Americans facing mental health challenges, Dr. Ramsey and I discuss the effects of loneliness, connection, and the quality of attachment. We explore the importance of boundaries and self-awareness, as well as the stigma surrounding mental health issues, and we dive into public awareness of mental health, factors that negatively affect brain health, and the crucial role of sleep in overall well-being. Our conversation also includes insights on how to find high-quality mental health care from qualified professionals, and we look at protective factors for our brains, like neuroplasticity, inflammation reduction, and maintaining a diverse microbiome.  I hope you find this insightful discussion with Dr. Ramsey as valuable, engaging, and enlightening as I did while recording it. IN THIS EPISODE YOU WILL LEARN: The challenges of being in a caregiving role Perimenopause and the impact on women's health Dr. Ramsey explains the concept of interpersonal psychotherapy Why self-awareness is necessary for improving mental health How social media and modern lifestyles impact mental health Urban living and its impact on sleep and mental health Mental health benefits of maintaining a diverse microbiome and avoiding ultra-processed foods Strategies for improving sleep quality Why personalized mental health treatments are essential The role of psychedelic medicine in mental health treatments Bio: Dr. Drew Ramsey Drew Ramsey, MD, is a board-certified psychiatrist, author, and leading voice in Nutritional Psychiatry and integrative mental health. He is a Fellow of the American Psychiatric Association and the founder of the Brain Food Clinic and Spruce Mental Health. For twenty years, he served as an assistant clinical professor of psychiatry at Columbia University, where he taught and supervised psychotherapy and nutritional psychiatry. Dr. Ramsey has authored five books, including Healing the Modern Brain, and three e-courses. He is a dynamic speaker, podcast host, and educator who has delivered three TEDx talks, and his work has been featured by The New York Times, The Wall Street Journal, the Today Show, NPR, and other notable outlets. He lives in Jackson, WY, with his wife and family. Connect with Cynthia Thurlow   Follow on Twitter Instagram LinkedIn Check out Cynthia's website Submit your questions to support@cynthiathurlow.com Connect with Dr. Drew Ramsey On his website On Instagram Healing the Modern Brain: E-course  Healing the Modern Brain: Nine Tenets to Build Mental Fitness and Revitalize Your by Drew Ramsey, M.D. is available anywhere books are sold

You think you're optimizing your brain—but what if the real culprit behind your brain fog, anxiety, and burnout is the modern world itself? In this episode, Columbia University psychiatrist and nutritional neuroscience pioneer Dr. Drew Ramsey joins Dave Asprey to decode the biological chaos hijacking your mind—and how to fight back. From inflammation and gut dysbiosis to screen-induced disconnection and hidden trauma, this is the ultimate roadmap for healing the modern brain. You'll explore the cutting-edge science of neuroplasticity, discover how movement and social connection trigger brain growth, and learn why food is still your most powerful antidepressant. Plus: dancing, psychedelics, kale debates, and why porn is quietly reshaping the male brain. What You'll Discover in This Episode: • Why brain fog, anxiety, and mood swings might be signs your brain is inflamed • How movement—especially dancing—can literally help your brain grow stronger • What your gut has to do with your mental health (and why some “healthy” foods can backfire) • The truth about antidepressants, supplements, and why there's no one-size-fits-all fix • Why porn, ultra-processed food, and doomscrolling are silently wrecking focus and drive • A new way to think about mental fitness—like a workout plan for your brain SPONSORS -BodyHealth | Go to https://bodyhealth.com/ and use code DAVE20 for 20% off your first order of PerfectAmino. -Zbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order. Resources: • A Day of Biohacking and Consciousness Event April 12th: https://daveasprey.com/biohacking-and-consciousness/ • Dave Asprey's New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ • Drew's Instagram: https://www.instagram.com/drewramseymd/?hl=en • Drew's Linktree: https://shorturl.at/CIIR5 • Danger Coffee: https://dangercoffee.com • Dave Asprey's Website: https://daveasprey.com • Dave Asprey's Linktree: https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com • Own an Upgrade Labs: https://ownanupgradelabs.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com Timestamps: • 00:00 – Trailer • 01:43 – Intro • 02:51 – The State of Mental Health Today • 04:00 – Nutritional Psychiatry and Personal Experiences • 05:21 – Environmental Factors and Brain Health • 05:55 – Chemical Balance and Psychiatry • 09:19 – Mental Fitness and Connection • 14:17 – Modern Brain Challenges • 16:26 – The Role of Movement and Dance • 22:44 – Sex, Relationships, and Mental Health • 34:02 – Microbiome and Mental Health • 36:50 – Transitioning to Urban Life and Mental Health • 37:29 – The Role of Nature in Mental Well-being • 38:14 – Personal Experiences with Gut Health • 39:45 – Trial and Error in Mental Health • 42:16 – Cognitive Resilience and High Performance • 45:37 – The Importance of Family Meals • 46:33 – Challenges of Rural and Urban Living • 47:53 – Brain Health: Beyond Neurons • 49:01 – Neuroplasticity and Mental Fitness • 52:50 – Biohacking Mental Health • 57:31 – The Role of Serotonin in Depression • 01:03:57 – Debating the Benefits of Kale • 01:12:03 – Final Thoughts on Mental Health and Resilience See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Today, we're diving deep into an important topic in the world of sports and beyond – concussions. Our host, Chris Duffin, welcomes guest Anthony Castor to explore the complexities of traumatic brain injuries, often caused by sudden jolts or blows to the head. The episode uncovers the neurological changes that these injuries entail, discussing both their short-term symptoms, like headaches and confusion, and long-term effects, including cognitive impairment and mood disorders. Moreover, Chris and Anthony delve into a variety of healing protocols, emphasizing the pivotal role of peptides in recovery. Whether you're an athlete or someone curious about brain health, this episode offers vital insights on tackling brain injuries and fostering resilience. Tune in and learn about strategies to not only manage but also prevent the implications of concussions.  

Are brain fog, fatigue, and mental exhaustion holding you back?  These symptoms aren't just stress-related or signs of aging. They're often caused by hidden brain inflammation! In this episode, my guest, Dr. Datis Kharrazian, and I discuss neuroinflammation – What it is, what causes it, and how it affects brain function, mood, and overall health. You'll discover how factors like stress, diet, gut health, and past head injuries contribute to brain inflammation and what you can do to reduce it. You'll learn practical lifestyle changes, nutrition tips, and brain-boosting strategies to improve focus, energy, and mental clarity. You'll hear more on: How brain inflammation starts—and why it's often caused by everyday factors like stress, diet, or past injuries What you can do to calm inflammation naturally, including dietary changes, supplements, and specific lifestyle shifts Why understanding your triggers —from food sensitivities to emotional stress — is the key to protecting your brain from long-term damage How to optimize your brain health using tools like intermittent fasting, anti-inflammatory diets, and proper sleep routines  Whether you've experienced brain fog, recovering from an injury, or just want to preserve your brain function for the future, this episode will give you the tools and knowledge to take control of your brain health!   For more information and show notes, please visit our website: https://biologyoftrauma.com/biology-of-trauma-podcast/

In today's episode of The Root Cause Medicine Podcast, we explore the often-overlooked importance of brain health and how it directly impacts our quality of life with Dr. Austin Perlmutter. You'll hear us discuss: 1. Brain inflammation 2. Brain-related conditions in women 3. Detoxification and brain health 4. Lifestyle choices supporting brain health 5. Supplements for brain health Dr. Austin Perlmutter is a board-certified internal medicine physician, a New York Times bestselling author, and a published researcher. He is also a health investor and international educator dedicated to helping people improve their health by addressing the biological roots of "stuckness" in the brain and body. Currently, Dr. Perlmutter serves as the executive director and research lead at Big Bold Health. Order tests through Rupa Health, the BEST place to order functional medicine lab tests from 30+ labs - https://www.rupahealth.com/reference-guide

In today's episode with Dr. Gary Kaplan, you'll hear us take a deep dive into: 1. Autoimmune diseases and chronic illnesses 2. The impact of chronic inflammation on the brain and body 3. The role of sleep in brain health 4. PANS, PANDAS, and POTS 5. How to find a doctor that listens to your symptoms Dr. Gary Kaplan is the founder of Kaplan Center for Integrative Medicine, specializing in the treatment of chronic pain for over 25 years, and the author of "Total Recovery: A Revolutionary New Approach to Breaking the Cycle of Pain and Depression" and "Why You Are Still Sick, How Infections Can Break Your Immune System & How You Can Recover." Dr. Kaplan is also board-certified in Medical Acupuncture and has studied and practiced Osteopathic Manipulative Medicine, Regenerative Medicine, and Emergency Medicine. Order tests through Rupa Health, the BEST place to order functional medicine lab tests from 30+ labs - https://www.rupahealth.com/reference-guide

Today, I'm excited to share a free 21-minute class from concussion expert Dr. Jeremy Schmoe at The Functional Neurology Center. It's one of the many classes available within The Concussion Community. In this session, you'll learn: Why a lack of motivation can be linked to brain inflammation How to identify if you're experiencing brain inflammation Practical steps you can take to address it For more insights, don't miss the article Dr. Schmoe refers to in the podcast: https://thefnc.com/research/do-you-have-brain-inflammation/ We will open the doors to The Concussion Community from January 6th to January 12th. For more information or to join the waitlist, click here.

In this episode of the Re-MIND Podcast, Dr. Ashleigh Moreland shares her personal journey and professional insights into the complex factors that drive challenging behaviour in children. Together with co-host David Masterton, they delve into the role of brain inflammation, environmental toxins, trauma, and neurodivergence in shaping a child's actions. Drawing from her lived experience as a parent and her expertise in neuroplasticity, Dr. Ashleigh provides actionable advice and practical strategies for parents who feel overwhelmed, lost, or desperate for answers. Whether it's understanding the gut-brain connection, the impact of chronic stress, or exploring conditions like PANS and PANDAS, this episode offers hope and a roadmap for navigating these challenges. Tune in to uncover how addressing these underlying issues can not only transform your child's behaviour but also repair and strengthen your relationship with them. This heartfelt conversation is packed with tools, tips, and real-life examples to help parents support their children's journey to becoming happy, healthy, and thriving individuals. If you've ever wondered why does my child act this way?, this episode is for you. YouTube: https://youtu.be/AGidZkVg-R0 Rise and Thrive: https://riseandthrive.re-mind.institute/ David's Linktree: https://linktr.ee/accidental_ascension Website: www.re-mind.institute Facebook: Re-MIND Institute Instagram: https://www.instagram.com/remind.institute https://www.pinterest.com.au/ReMINDInstitute/?fbclid=IwAR0y56gD4nbAop_524-LtAAO2y1FDhIQv2dK9TTl0Zbo08TVNIdguSTjhYQ [Disclaimer: The Re-Mind Podcast provides general information and discussion about various mental health and well-being topics. The content in this episode is for informational purposes only and should not be considered as professional advice. If you or someone you know is facing mental health challenges, we encourage seeking support from qualified professionals.]

What can we do about the brain inflammation that holds us back in fog, fatigue and trauma responses?  To help answer that question and share brain inflammation with you is my guest, Dr. Austin Perlmutter, is a board-certified internal medicine physician, New York Times bestselling author, published researcher, and the executive director for Big Bold Health, a food-as-medicine company focused on helping people rejuvenate health through better immune function. In the evolving field of trauma therapy, we're increasingly recognizing that healing isn't just about processing memories or changing thought patterns. The application of The Biology of Trauma lens is that it is just as much about addressing the impact trauma has had on our biology, which now keeps us stuck in our trauma responses.  One crucial aspect of this biological impact is brain inflammation. It is one of the most common yet most overlooked gatekeepers of trauma healing. Brain inflammation creates many of the symptoms that people attach to their trauma responses, yet often is what is triggering those trauma responses. Yes, you heard me right. It is not just people, places that can trigger our trauma response. It is also a specific immune cell in our brain - microglia.  In this episode, you'll learn why: Good insights from therapy seem to fade by the next day Small stresses feel overwhelming to your brain What you eat affects how well you can process emotions Relationship conflicts leave you mentally exhausted Your diet can dysregulate you just as much as your partner Your mind feels clearer in nature than in therapy For more information and show notes, please visit our website: https://biologyoftrauma.com/biology-of-trauma-podcast/

In this episode of the Tick Boot Camp Podcast, hosts Matt Sabatello and special guest co-host Michelle McKeon sit down with Dr. Napatia T. Gettings, a Double Board Certified Psychiatrist and Lyme Literate specialist, to explore the intersections of brain health, Lyme disease, and cutting-edge diagnostic tools like SPECT imaging. What You'll Learn in This Episode Dr. Gettings' Journey to Lyme Literacy Discover how Dr. Gettings transitioned from medical school to private practice and became a partner at Amen Clinics. Learn about her expertise in treating child, adolescent, and young adult brain health and the integration of multiple medical specialties in her practice. Unveiling the Power of SPECT Imaging Understand what SPECT (Single-Photon Emission Computed Tomography) imaging is and how it differs from traditional CT scans. Learn why SPECT imaging is vital for identifying brain activity abnormalities, including inflammation, and its challenges in obtaining insurance coverage. Brain Inflammation and Tick-Borne Diseases Explore how SPECT scans can detect brain inflammation caused by toxins, pathogens, and autoimmune conditions. Dive into case studies, including patients misdiagnosed with psychiatric conditions later found to have infections like Babesia. Treatment Approaches for Lyme and Inflammation Discover the role of multi-disciplinary care in addressing tick-borne diseases and brain health. Learn about treatment modalities such as hyperbaric oxygen therapy, anti-inflammatory medications, and nutraceuticals. The Role of Cannabis in Brain Health Get insights into the benefits and risks of CBD and THC in managing inflammation and mental health. Understand the importance of education and individualized treatment plans when considering cannabis use. Navigating Mental Health and Trust Hear Michelle McKeon's personal story about overcoming mental health challenges and finding a supportive psychiatrist. Explore the critical role of trust in the doctor-patient relationship when treating complex conditions. Misdiagnosis and the Need for Better Diagnostics Learn why inadequate medical workups often lead to psychiatric misdiagnoses. Understand the importance of accessible, accurate diagnostics in mental health care. Key Takeaways and Resources Discover the Amen Clinics' resources, including examples of SPECT scans showing differences between healthy brains and those affected by Lyme disease. Hear Dr. Gettings' call to normalize brain scans as essential diagnostic tools for neuropsychiatric symptoms. Find actionable advice on improving health literacy and accessing comprehensive care. This episode is packed with valuable insights for anyone navigating Lyme disease, mental health challenges, or looking to optimize brain health. Tune in to uncover the science behind SPECT imaging and its life-changing applications in psychiatric care.

In this episode Dr. Perry discusses his journey of healing brain inflammation by cleaning the brain waste draining toilets. Dural venous sinus, glymphatics, and the newly discovered brain meningeal layer.  Yes there is hope for brain fog and inflammation. Website: https://www.stopchasingpain.com/ Big 6 Lymph Reset: https://www.stopchasingpain.com/the-big-6-tm/

Superimposed on an impressive body of work on the blood-brain-barrier and immune system, Prof Akassoglou and her collaborators just published an elegant study in Nature that centered on the direct binding os the SARS-CoV-2 spike protein to fibrin with marked downstream pro-inflammatory effects. The findings and potential treatments have implications beyond Covid, Long Covid to other neurologic diseases.Full videos of all Ground Truths podcasts can be seen on YouTube here. The audios are also available on Apple and Spotify.Transcript with links to audio and to relevant papers, graphicsEric Topol (00:07):Well, hello this is Eric Topol with Ground Truths, and with me today is Katerina Akassoglou. She is at the Gladstone Institute and she is a remarkable neuroimmunologist who has been doing extraordinary work for three decades to unravel the interactions between the brain, blood vessels and the role of inflammation. So Katerina, there's a lot to discuss, so welcome.Katerina Akassoglou (00:40):Thank you. Thank you so much. It's a great pleasure to join.By Way of BackgroundEric Topol (00:43):It's really interesting going back in your career. First of all, we're thankful that you immigrated here from Greece, and you have become one of the leading scientists in this discipline of important discipline of neuroimmunology, which is not just about Covid that we're going to talk about, but Alzheimer's and neurodegenerative diseases. This is a really big hot area and you're definitely one of the leaders. And what I was impressed is that all these years that you've been working on the integrity of the blood-brain barrier, the importance of fibrinogen and fibrin, and then comes along the Covid story. So maybe what we can do is start with that, which is you've made your mark in understanding this whole interaction between what can get into the brain, through the blood-brain barrier and incite inflammation. So this has been something that you've really taken to the extreme knowledge base. So maybe we can start with your work there before we get into the important seminal Nature paper that you recently published.Katerina Akassoglou (01:57):Yes, of course. So since very early on, I was still a graduate student when we made the first discovery and at the time was like mid-90s, so it was really ahead of its time. That dysregulation of cytokine expression in the brain of mice was sufficient to induce the whole cascade of events, triggering neurodegeneration, demyelination in pathological alterations, very reminiscent of multiple sclerosis pathology. And it was really hard to publish that study at the time because it was not yet accepted that this regulation of the immune system modeling the brain can be linked to neurodegeneration. So that was 1995 when we made that discovery, and I became really interested, what are the pathogenic triggers that actually polarized the immune cells in the brain? So with this, of course, this transgenic animal was expressing TNF, it was an artificially made animal that we made, but naturally what were the triggers that would polarize the innate immune cells? So I looked really early on in this mice and what I found was that the very first event was leaks of blood-brain barrier. It was opening of the blood-brain barrier in this mouse before inflammation, before demyelination, before neuronal loss. And this is really what shaped the question that, is it possible that these blood leaks that happened very early in the pathology, could this be the instigators of pathogenic inflammation in the brain?Eric Topol (03:34):Yeah. So in a way, you got at this question because of the chicken-and-egg and what happens first, and you got to the temporal saying, which happened first as you said, the leak before you could see evidence of inflammation and being able to study this of course in the experimental model, which you couldn't really do in people. And what I love about the description of your career, which has been quite extraordinary contributions is connecting the dots between the blood, the inflammatory response and the brain. Perhaps no one has done that like you have. And before we get into the recent paper, a lot of people are not aware that a year ago, a group in the UK known as PHOSP-COVID, they published a really important paper in Nature Medicine of over 1,800 people who were hospitalized with Covid and they found that fibrinogen was the best marker for cognitive deficits at 6 and 12 months (Figure below)(04:40):So that's just one of many papers, but it's a particularly well done study that already before you got into this work that recently published had emphasized fibrinogen. And by the way, again, having spent a lot of years in clots in the arteries, for me, we have to just get it down to fibrinogen plus thrombin gets you to fibrin. Okay, so fibrin is a major player here when fibrinogen is cleaved. So here we have the basis that you established, which is the fibrinogen leakage into the brain, activating inflammation, activating microglia, which like the macrophages of the brain and inciting the whole process. And before we close, I want to not just talk about Covid, but Alzheimer's too. But now let's get into the study that you did, [Fibrin drives thromboinflammation and neuropathology in COVID-19] which is striking, I mean really striking. And can you kind of take us through, because you not only demonstrated the importance of fibrin in inciting neuroinflammation in this model, but also how you could reverse it or prevent it. So this, and you looked at it in many different ways, this was a systematic approach. Maybe you can take us through how you were able to make such compelling evidence.The Multimodal EvidenceKaterina Akassoglou (06:09):Yes, thank you. First of all, thank you for bringing up the human relevance because this was also our inspiration for the work that we did in the Covid study. So as you mentioned in Covid patients, fibrinogen unbiased mass spec analysis was identified as the predictive biomarker for cognitive impairment in Long Covid patients. And this was in addition to also neuropathology data about the abundance of fibrin deposition in the brain. And these were studies that were done by NIH that have found deposition of fibrin in the brain and the reports for the abnormal and puzzling coagulation in Covid that is not setting other infections and also in many cases not always relating with the severity of symptoms. So even mild cases of Covid also had increased coagulation. I was really intrigued by this human, all this evidence in human data, and I thought that maybe the way that we're thinking about this, that it's systemic inflammation that drives the clotting.(07:24):Maybe there's another aspect to this. Maybe there is a direct effect of the virus with the coagulation cascade, and in this way maybe this can be an instigator of inflammation. So this was the original idea to be able to reconcile this data from the clinic about why do we have this prevalence of coagulopathy in Covid. And of course, the second question is, could this also be a driver of the disease? And of course, we're in a unique position because we have been studying this pathway now for over 20 years to have all the toolbox, the genetic toolbox, the pharmacologic toolbox to be able to actually really address these questions with genetic loss of function studies, with a blood innate immunity multiomics pipeline that we have set up in the lab. And of course, with preclinical pharmacology in our ABSL3 facility. So we had the infrastructure in place and the source in place to actually really dissect this question with both genetic tools as well as also technology platforms.Eric Topol (08:29):And you had in vivo imaging, you're the director of in vivo imaging for Gladstone and UCSF. So you do have the tools to do this.Katerina Akassoglou (08:38):Yes. The imaging that you mentioned is really important because this is, we employed that very early in our studies over now 15 years ago. And the reason was sometimes from snapshots of histopathology, you cannot really understand the sequence of events. So by being able to image these processes, both neuronal activity, microglia activation, infiltration of peripheral cells in the brain, this is how we could see the steps that what happens early on and to be able to answer these chicken-and-egg questions that you mentioned. So these were very, they're very important experiments, especially at the beginning because they were hypothesis driving and we were able to ask the right questions to drive our research program.Eric Topol (09:26):Now was the binding of the spike protein to one key site in fibrinogen, was that known before? [See outstanding Figure below from Trends in Immunology]Katerina Akassoglou (09:36):No, this was not known. So there was evidence that there are abnormal clots in Covid, but it was not known whether the spike protein would directly bind to protein to the coagulation cascade. So one of the key discoveries in our study was to use peptide array mapping and be able to identify not only the binding, but exactly the domains on fibrin that spike binds too. And what we found was two key domains, one the inflammatory domain and the other the plasmin binding site, which is important for fibrin degradation. So this suggested a potential dual deleterious role for this interaction, both by maybe affecting inflammation, but also delaying fibrinolysis, which is the degradation of this toxic protein from the brain. And indeed, we found that this interaction was responsible for all these two aspects, including decreased degradation, more inflammation, but also at the same time increased, increased coagulation. So it was a really pathogenic interaction.Eric Topol (10:47):Yeah, actually it's pretty striking. You have these two sites, the plasmin cleavage site of fibrinogen, which as you say, we knew there was a problem with clots. We knew that, but we didn't know exactly the spike protein how exactly it was implicated, particularly with fibrinogen. And then this other site, the CD11b-C18, now that's fancy for surface receptors of macrophages. And basically, this is critical because it's this microglia activation in the brain, and I know you saw it in the lungs as well through this other site that spike protein activated. So you had a twofer here of things that you discovered that the SARS-CoV-2 spike protein was capable of doing. This was a really big revelation. And then you also looked at mice that were genetically manipulated. So maybe you can, because before we get to your antibody monoclonal, the ways that you proved this were, I mean, one thing after another is really systematic. So maybe you can teach us about that.Thanks for reading Ground Truths! This post is public so feel free to share it.Establishing CausalityKaterina Akassoglou (12:08):Yeah, sure. So the first was about chemistry experiment. So this of course, we had to get to the next step to see is there any causality for this pathway. So we employed genetic loss of function studies and we had knockout mice, either fibrinogen knockout mice, this mice have all blood proteins except fibrinogen, and they have a delay in coagulation so they don't clot properly. But we also had a mutant mouse, which is a fibrinogen NK mouse. And this was a mutation only within this inflammatory domain that you mentioned, inflammatory domain that binds to C11b-C18. Other names for this is of course complement receptor 3, Mac-1 (αMβ2). It's the same, many names for this receptor, that as you mentioned, is expressed not only in microglial in the brain, but also peripheral immune cells including macrophages as well as also neutrophils which are CD11b expressing.(13:12):So we now have genetic models to be able to look at both complete depletion of fibrinogen, but also a very specific mutation and very selective mutation that only blocks the inflammatory properties without affecting the properties of fibrin in hemostasis. And these mice were made many years ago by a very close collaborator, Jay Degen at the University of Cincinnati. So what we found is that when we block either the inflammatory domain or we completely deplete fibrinogen, there was this profound protection after infection in internasal infection with the virus in lung inflammation. And this was both suppression of oxidative stress and this pathogenic inflammation in the lung, but also decreasing fibrosis, which has been associated with also Long Covid. And the surprise came from the transcriptomic data. So when we did transcriptomic analysis in this mice in the lungs, we found perhaps the expected decrease in the immune signatures in macrophages. This was in line with our previous work in, as you mentioned, Alzheimer's models, multiple sclerosis models. But what also was really surprising is there was that genes that are associated with activation of NK cells were upregulated. And of course this was the first time we had infected these mice, previously we had not done an infection before. So I think that maybe because of this region we had not seen before in our data this immunomodulatory role of fibrin that not only surprises the macrophage response, but also increases these NK cells that are important for viral clearance.Eric Topol (15:00):So again, the finding another important unique finding is the natural killer (NK) cells and effect there from the activation of this, as you said, the inflammation site or the CD11b-C18 that we've been talking about. So now another layer of this, a dimension of your Nature paper was that you tested an antibody that you already had developed so-called 5B8. A monoclonal that specifically binds to the domain of the one we're talking about this inflammation domain of fibrinogen. So can you tell us about what that showed?Katerina Akassoglou (15:45):Yes, so we tested this antibody in different models of Covid, which were both models with neuroinvasion and models without neuroinvasion. So we used both transgenic mice for hACE2, the human ACE2 infected with Delta, but we also use mouse adapted viruses like Beta that is just in the wild type mice with no transgenic being involved that these are without neuroinvasion. And we wanted to see if the antibody had any potential protective effects. And what we found is that the antibody protected from inflammation in the lung. So the data looked so similar with a genetic mutation of this pathway, protection from inflammation, decreased fibrosis, increased viral clearance, so decreased spike and viral proteins in the lungs. But we also found a protection in the brain. So the brains of this mice, including both the models we used with neuroinvasion and without, they both have had microglia activation in the brain. And we also found neuronal loss in the Delta infected mice and the antibody protected from both neuroinflammation but also improved neuronal survival in the mice. Showing that there can be this despite regardless of which model we used, there was this protective effect suggesting that by blocking fibrin, either the periphery or in the brain, this could be protected for these models.Eric Topol (17:28):Yeah, so I mean this is fascinating because until now, until this report of yours and your colleagues at Gladstone, there was knowledge that there would be neuroinflammation from Covid, both in patients from various biomarkers and imaging as well as in experimental model. But what this did was take it to the fibrin story, and I guess that's one of the questions you nailed that how important fibrin is, but that doesn't necessarily rule out other triggers of neuroinflammation, right?Katerina Akassoglou (18:04):Oh, absolutely not. So I think that this is one of the mechanisms that can be very important, especially in some patients. But we know that there are additional of course mechanisms of neuroinflammation including auto-antibody responses, as well as also endotheliopathy that are persistent endotheliopathy, this can be interacting also with each other. So I think that it's important for future research that we understand how do these mechanisms feed into each other? Are there a positive feedback loops between autoimmune mechanisms and coagulopathy and endothelial dysfunction with inflammation? But I think most importantly, I think that if we're thinking of this in the context of patients, can we identify patients with mechanism that might be more prevalent in specific cases of Long Covid and tailor our potential future clinical trials towards the needs of Long Covid patients?Towards TreatmentEric Topol (19:06):Absolutely. I did interview some months back on Grounds Truths, Michelle Monje at Stanford, who I'm sure and interact with, and she's also works not so much on the fibrin side, but on neuroinflammation and the likeness between this condition in people and chemo brain because of the inflammation that's seen there. So we've talked about the multiple triggers that could contribute to brain inflammation, which I think most people would say in Long Covid this is one of the most, besides obviously the lack of energy, the profound fatigue and disability, but the cognitive function hit, not just brain fog is often profound. And we've just seen some reports about that, and particularly in hospitalized patients, how bad that can be. So that gets us to a potential treatment. Now, one of the things that's out there dangling, there's many things that people have talked about in terms of why can't we have a treatment for Long Covid?(20:13):And now of course this fibrin pathway, if you will, lends itself to many possibilities, whether it's anticoagulants or fibrinolytics like a tPA or things like nattokinase, which is a Japanese food enzyme that you could get at the nutrition centers or whatever. What are your thoughts? Because we don't have any good studies. There are all these little, tiny studies and they don't provide much conclusion, and you have an antibody that could potentially be effective. As I understand it, you set up a company some years ago, Therini Bio and used to be called MedaRed. You're the first woman scientist at Gladstone to develop a spin out company, which is another point of congratulations on that. But could the antibody be tested in patients or what do you think about these other possibilities?Katerina Akassoglou (21:15):Yes, yes. These are great questions. So first of all, the different approaches that you mentioned have very different mechanism of action. So degrading fibrin, the degradation products of fibrin also can have deleterious effects. The dimer, for example, can be very pro-inflammatory. So at the same time, blocking coagulation can also have a diverse effects because this can lead to excessive hemorrhage. So the approach that we took was to selectively block the inflammatory properties of fibrin without affecting beneficial effects of the molecule in normal hemostasis. So the challenge when I made the antibody was to be able to dissect these two functions of fibrin. It's our most important clotting factor, but at the same time, a molecule with profound pro-inflammatory capacity. So the observation that these two domains, the clotting domain and inflammatory domain were not overlapping, was really the foundation of this invention was that we could maybe create this antibody to be able to target them in a selective way.Other Neurologic Conditions (22:31):So the antibody I developed is neutralizing blood toxicity by blocking the inflammatory domain of fibrin without adverse coagulation effects. And it's now completing phase one trials. So it has already completed the single ascending dose at 40 milligram per kilogram. It's interim data were announced already for this trial, with no safety signals. So if the antibody completes this year, the phase one trials, then it should be possible to be tested in different patient populations. You mentioned before chemo brain, and I think it's important that we think that blood-brain barrier disruption occurs among many neurological conditions, and it's an early event associated with early disease onset and worse prognosis in multiple sclerosis, Alzheimer's disease, traumatic injuries. So I think that it's by developing a strategy, therapeutic strategy to neutralize blood toxicity, this can have applications in a wide range of neurological conditions with vascular dysfunction.Eric Topol (23:54):Yeah, no. In your Nature Immunology 2020 piece [Figure below], you started with the 1883 identification of multiple sclerosis (MS) lesions were “engorged with blood”, the first link between blood leaks and brain inflammation. So this has enormous potential. And what I like about this Katerina is that you've dissected the clot component versus the inflammatory trigger of the fibrinogen and fibrin story. And this is so vital because if you keep throwing these things that just going to work on the clot and not deal with the pro-inflammatory consequences, then you're going to get the wrong impression that clots are not that important. And by the way, you did mention, and I want to come back to that too, endothelial inflammation, which is another feature of Long Covid is another kind of interactive part of this because when the lining of the blood vessel is inflamed, it will attract microthrombi and also be a participant in this whole affair. What do you think about Alzheimer's and the prospects of being able to interfere with Alzheimer's? We have 20 years in someone before this process takes hold and meets clinical manifestations. Would an antibody like this ever be useful along the way?Katerina Akassoglou (25:29):Yeah, so well, our antibody was tested first in Alzheimer's, this models when it was originally published, and we performed reversal trials in Alzheimer's models. So we dosed mice when they have established amyloid plaques, microglia activation, neuronal loss, and we could reverse this effect so it could increase cholinergic neurons in mice, reduce inflammation in a very selective way, only the neurotoxic part of inflammation and for genetic depletion of this pathway with akin mice in Alzheimer's disease. Also, improves from cognitive impairment, and we now have a new paper in Cell Press that is showing this effects also with really nice and unbiased machine learning models for behavioral segmentation [Figure below].So I think that there is the data both from genetic studies and the antibody show projection in Alzheimer's disease. And of course, as you might have read the recent Lancet report from the Lancet committee on dementia that identified the vascular risk factors as the key contributors, especially post sporadic cases of Alzheimer's disease that is over 90% of Alzheimer's disease that is not genetically linked.(26:58):So I think that there is a real need in Alzheimer's disease to be able to block this vascular induced pathology. And an antibody like the fibrin neutralizing therapy could be positioned to be protective from the vascular induced immune-mediated neurodegeneration in this disease as well. I mean, ultimately, I think that we need to be thinking the terms of efficacy. So we want to have a drug that is efficacious, but we also want it to be selective. And the selectivity is really important because the immune system has so many protective functions. So if we block phagocytosis, we end up with more debris, decrease of neurorepair, anti-myelination. So by blocking a ligand here and not blocking, not eliminating a cell type or blocking a global pathway in this cell, but biologic a single ligand, I think we have been able to achieve this balance between efficacy, but also safety because we only block this neurotoxic populations and not the entire innate immune response that also has been beneficial for metastatic functions in the brain.Blocking NeuroinflammationEric Topol (28:19):So you're bringing up another critical concept about targeting the inflammation, this kind of goldilocks story of how much you interfere with the immune response and how much you are able to reduce the adverse pro-inflammatory effects. So that gets me to what if we don't know in any given patient how much fibrin is having a role in their Long Covid. Although we know it has to be a prominent feature because we saw it in, not just a hospitalized patient series that I mentioned we reviewed, but other papers as well. But what about if you just try to take on inflammation like through a GLP-1 drug or cGAS–STING or any of these really strong anti-inflammatory pathways. Do you see a difference in a generalized approach versus a specific approach that is really fibrin centered?Katerina Akassoglou (29:22):Yeah, so we have a focus actually on both because we wanted to dissect the downstream intracellular pathways of fibrin, and it's interesting that we can find specific inflammatory mediators that potentially can also be targeted as well, to be able to preserve that specificity, which I think is really important because if we don't preserve the specificity, we'll end up with a lot of adverse effects by eliminating major immune responses. But the point that you raised I think is really important because it's not enough to have an efficacious and selective drug if you don't know the patient population that will benefit from this drug. So I think that in addition to the drug discovery studies, it's important to develop also biomarker programs with both fluid biomarkers, but also imaging biomarkers to be able to identify the patient populations that will benefit from such treatment.(30:25):So if for example, a patient population has a fibrin deposition, blocking only downstream might not be enough, and it might be really important to neutralize this fibrin toxicity in the brain of patients. And with our target engagement studies, we show that at least in animal models, the antibody can be there. So I'm very encouraged by also programs that are going on now in the scientific community to develop noninvasive ligands to be able to image fibrin in the brain that are already tested in different patient populations like multiple sclerosis. Because I think we're going to learn so much from the biology as we start interrogating and asking these questions now in different patient populations.Eric Topol (31:14):I think that's a vital point you're making because the success of a clinical trial here in a clinical syndrome that is mosaic with lots of different types of pathways. If you can nail down the patients that would have the most to stand to benefit from a particular intervention, that the chance of you not missing the benefit that is matching the marker, what image marker or other markers is so vital. Well, we've talked, I think, about some fascinating discoveries that you and your colleagues have made. I mean, it's really extraordinary, and obviously we need this in Long Covid. But you know what, Katerina, it's almost made me think that you were warming up to this for three decades, that somehow or other you were working on all this stuff and then came Covid. Is that how you see it, that somehow or other you didn't know that all the work you were doing was going to wind up in this space?Katerina Akassoglou (32:18):Oh, I never thought I would work in a virology project. This collaboration started over Zoom with Warner Greene. We were both sheltering in place. It was the beginning of the pandemic, and the first reports were coming out about this puzzling coagulopathy. And our labs were hardly operational at the time, as you know, we had to close down our labs for a while. And however, this was a very big problem, and we thought that this is our role as scientists. If we feel that we can contribute and we have the tools to contribute, we felt that it's important that we pivot some part of our research, and even we wouldn't be doing this before, but it was important to pivot a part of our research and collaborate. And I think studies like this, this study would have been impossible without a team of collaborators. As you know, there were over 50 scientists involved at Gladstone, UCSF, UCLA, UCSD, Stanford University. Without collaboration, this study wouldn't be possible. So I'm really grateful to everyone who came together to solve this problem because I think that's what scientists should be doing. We should be solving problems as they arise.Eric Topol (33:41):Well, and also, I think a lot of people don't realize that, for example, when the Covid vaccines came along, people think, oh, well, it all got done in 10 months since the sequence of the virus, when in fact it took 30 years at least between all the factors that went into having an mRNA and sequencing virus and nanoparticles. And in many ways, your arc of this work is like that because it took three decades to have all the tools and the basic understanding, the antibody that you had developed for different reasons and this fascinating unraveling of what's going on in the model and undoubtedly in some patients at least as well. So before we wrap up, have I missed anything about this just remarkable work you've done?Katerina Akassoglou (34:33):Oh, thank you. I just want to thank you for this discussion and thank you for emphasizing the different areas and the different decisions that this pathway can have implications both for our understanding, our basic understanding of the blood brain immune interface, as well as also potential translation. And I think that the curiosity sometimes of how things work, I never thought it would work on Covid, like you mentioned at the beginning, but I think that basic science and curiosity driven science can sometimes lead to discoveries with translational implications that hopefully might benefit patients one day.Eric Topol (35:21):Yeah, well, undoubtedly it will. We're indebted to you, Katerina and all the folks that you have teamed up with, connecting the dots at the neurovascular interface. Phenomenal work and will follow the subsequent with great interest and it will likely not just a story about Long Covid, but other areas as well, so thank you.*********************************Thanks for listening, reading or watching!The Ground Truths newsletters and podcasts are all free, open-access, without ads.Please share this post/podcast with your friends and network if you found it informative!Voluntary paid subscriptions all go to support Scripps Research. Many thanks for that—they greatly help fund our summer internship programs.Thanks to my producer Jessica Nguyen and Sinjun Balabanoff for audio and video support at Scripps Research.Note: you can select preferences to receive emails about newsletters, podcasts, or all I don't want to bother you with an email for content that you're not interested in. Get full access to Ground Truths at erictopol.substack.com/subscribe

Boost Your Wellness Journey: Study: Pathogenic hypothalamic extracellular matrix promotes metabolic disease https://www.nature.com/articles/s41586-024-07922-y Healthy Digestion Recipe Book for Weight Loss and Chronic Pain Relief https://rawfoodhealthempowermentsummit.com/healthy-digestion-recipe-book-download60594982 Join the Conversation: Subscribe to the Raw Food Health Empowerment Podcast and share this episode with anyone on their own path of health and transformation.  // HOST Samantha Salmon, Certified Brain Optimization Coach The information provided in this broadcast is for educational purposes only and is not intended as medical advice. These statements have not been evaluated by the food and drug administration, or the equivalent in your country. Any products/services mentioned are not intended to diagnose, treat, cure, or prevent disease.  RawFoodMealPlanner.com © 2024

https://renegadehealthboss.com In episode 128 Heather Gray FDN-P opens up about her personal journey with mental health, brain inflammation, and menopause. Heather discusses the stigmas surrounding these issues, especially for women in business, and shares her thoughts on the need for authenticity and vulnerability in the wellness space. Heather Gray discusses the importance of returning to health fundamentals rather than chasing after expensive treatments. In this podcast you will discover 00:00 Introduction to the podcast and its mission to challenge the status quo in health and wellness. 03:03 Heather reflects on the recent suicide of a friend and how personal experiences with mental health shape her perspective. 05:01 Heather discusses the challenges of being taken seriously after mental health struggles and the lingering effects of trauma. 08:50 Heather shares her experiences with weight gain linked to menopause and mold exposure, highlighting the difficulty of being perceived 10:07 Insight into brain fog and its similarities with menopause symptoms, along with the cognitive challenges it presents. 12:00 Heather emphasizes the importance of seeking professional help and running labs to assess hormone levels. 18:00 Heather discusses her personal supplement routine and the significance of foundational health strategies in her wellness journey. 20:49 Heather reflects on the overwhelming pursuit of costly treatments and highlights the magic of foundational health practices. 22:30 Heather stresses the importance of kindness and connection, reminding listeners of their intrinsic value and purpose. 24:00 A disclaimer is provided about the content being for entertainment purposes only, encouraging listeners to consult their doctors before making any medical changes To Get BioMed: Contact Dr. Drobot here https://thebiomedcenter.com/ Tel:480-614-5820 Only contact the Scottsdale location To get CAROL Bike Click here https://carolbike.com/ use code RHB to get $100 off the CAROL Bike offers a 100-day return policy. A full refund, buy with confidence. If you are a practitioner please open an account with MHP here www.mhpvitamins.com I'm Heather Gray, a Functional Practitioner, Lyme Boss, and owner of Renegade Health Boss. I'm passionate about helping people overcome chronic health conditions like Lyme disease, mold toxicity, and toxin overload. Learn all the tools I did to overcome Lyme, Mold and Autoimmune Diseases Get The Foundations of Health course: https://rhbcourses.com/ use code ACTION to save $100 on this easy to follow, life changing course. Get healthier food into your diet with these easy, yummy, fast meals today! Get more energy, less brain fog, and LESS pain when you start eating a low-inflammatory diet Download your free video series Real Cooking For Real Life here. https://renegadehealthboss.com/real-cooking-for-real-life-recipe-book/ #RenegadeHealthBoss #WellnessWisdom #TransformYourHealth #HealthyEating #MindBodyConnection #Health #SupportOneAnother #DietaryChanges #SustainableHealth #EmpowerYourself #thelymeboss #thereishope #HealthMatters #MentalHealthAwareness #ToxicBurden #WellnessWarrior #SelfCare #NutritionFirst #HealthTransformation #itsnotinyourhead --- Support this podcast: https://podcasters.spotify.com/pod/show/renegadehealthboss/support

Discover how Sean Christopher transformed his life in just four months! Join the Digital Social Hour with Sean Kelly as we dive into Sean Christopher's powerful journey of losing 90 pounds and overcoming health challenges.

If you have depression, anxiety, ADHD, or dementia  OR if you have had a TBI- you want to watch this video.  Brain inflammation is a serous concern that you will want to rule out and if you have it,  I'm going to share with you how to heal from it today and get your life back.  

DISCLAMER >>>>>>    The Ditch Lab Coat podcast serves solely for general informational purposes and does not serve as a substitute for professional medical services such as medicine or nursing. It does not establish a doctor/patient relationship, and the use of information from the podcast or linked materials is at the user's own risk. The content does not aim to replace professional medical advice, diagnosis, or treatment, and users should promptly seek guidance from healthcare professionals for any medical conditions.   >>>>>> The expressed opinions belong solely to the hosts and guests, and they do not necessarily reflect the views or opinions of the Hospitals, Clinics, Universities, or any other organization associated with the host or guests.       Disclosures: Ditch The Lab Coat podcast is produced by (Podkind.co) and is independent of Dr. Bonta's teaching and research roles at McMaster University, Temerty Faculty of Medicine and Queens University. Today, our host Dr. Mark Bonta sits down with the ever-knowledgeable Dr. Suman Chakrabarti to dive deep into the world of infections and their surprising sources. From the classic culprits, like poorly stored rice at church picnics causing sudden bouts of illness, to more exotic findings like respiratory diseases from parrots and toxoplasmosis risks for pregnant women, we've got it all covered.Dr. Chakrabarti sheds light on the curious link between avian flu and milk production, as well as the risks associated with common pets like dogs, cats, and even domesticated rodents. We'll navigate the complexities of bacterial and viral pneumonia, discuss the impact of antibiotics on treatment, and explore the looming threat of tropical diseases spreading due to climate change.Throughout this episode, you'll gain valuable insights into the history and evolution of infectious diseases and hear candid discussions on contemporary concerns, such as the necessity of additional COVID-19 boosters and our readiness to tackle new health risks. So, grab your headphones and join us for an enlightening conversation that promises to challenge your perceptions and expand your knowledge on all things infectious. Let's ditch the lab coat and get started!00:59 Medical educator with diverse expertise and humor.05:42 Avian influenza could become a pandemic virus.08:14 Limited testing may miss mild cases of illness.11:57 Interactions between animals and humans facilitate diseases.14:24 Medical students gather irrelevant patient information, specifically birds.19:10 Dog bites can cause serious infections, disfigurement.20:38 Risk of infection for those with spleen dysfunction.25:30 Influenza can lead to potential bacterial pneumonia.28:55 Livestock health, climate change, and disease risks.29:44 Climate change may bring new disease vectors.34:51 Podcast fosters learning, health, informed decision-making, experts' engagement.37:13 Acknowledgment to family and production and social media teams.

Dr. Aileen Marty, Infectious Disease Specialist and Professor at Florida International University, joins Bob Sirott to talk about the latest health news. Dr. Marty talks about farmers who have to kill some chickens due to bird flu and how brain inflammation could trigger psychosis.

Permeable blood brain barrier and gut barrier connected to inflammation and autoimmunity diseases is enough to make anyone's head spin. Dealing with these health conditions can be frightening and endless. Your body's reaction to proteins and your immune response can be highly frustrating when you're being instructed to follow “protocols” and standards of treatment. If you or someone you love has felt betrayed living a standard healthy lifestyle only to fall prey to gut issues, autoimmune disease and declining cognition, you're not alone. Dr. Datis Kharrazian is a world-renowned functional medicine health care provider. He specializes in managing chronic diseases, autoimmunity and neurological problems. He treats his patients with non-pharmaceuticals, and is in extremely high demand from patients and other healthcare professionals wanting to learn his clinical models. In this episode, Dr. Kharrazian is addressing the flaw with medical treatments that over standardize what people are experiencing and the causes. He's explaining why giving blanket treatments and protocols can cause patients far worse health conditions than where they started. Check out Dr. Kharrazian's book, Why Isn't My Brain Working: https://amzn.to/3wvDplt [Original air date: May 22, 2022]. SHOW NOTES: 0:00 | Introduction to Datis Kharrazian 0:37 | Do You Have Leaky Brain? 4:15 | The Problem with Gluten 16:48 | How Autoimmune Disease Happens 25:37 | Avoid These Foods 32:22 | Prevent Brain Disease 39:57 | Do This To Stay Healthy 51:10 | Push Neurological Limits Follow Datis Kharazian: Website: https://drknews.com/ YouTube: https://www.youtube.com/channel/UCgTTDpIy3DrhmKiP22BOEyQ Twitter: https://twitter.com/drkharrazian Instagram: https://www.instagram.com/datiskharrazian/ Facebook: https://www.facebook.com/datiskharrazianpage/ Podcast: https://drknews.com/podcasts/ FOLLOW TOM: Instagram: https://www.instagram.com/tombilyeu/ Tik Tok: https://www.tiktok.com/@tombilyeu?lang=en Twitter: https://twitter.com/tombilyeu YouTube: https://www.youtube.com/@TomBilyeu SPONSORS: Visit https://betterHelp.com/impacttheory today to get 10% off your first month. NetSuite has extended its one-of-a-kind flexible financing program for a few more weeks! Head to https://NetSuite.com/THEORY.  Sign up today at butcherbox.com/IMPACT and use code IMPACT to choose your Free for a Year offer, plus get $20 off your first order! Explore the Range Rover Sport at https://landroverusa.com For comprehensive financial news and analysis, visit the incredible brand that so many great investors use, https://yahoofinance.com.   Get 5 free AG1 Travel Packs and a FREE 1 year supply of Vitamin D with your first purchase at https://drinkag1.com/impact. Secure your digital life with proactive protection for your assets, identity, family, and tech – Go to https://aura.com/IMPACT to start your free two-week trial. Take control of your gut health by going to https://tryviome.com/impact and use code IMPACT to get 20% off your first 3 months and free shipping. ***Are You Ready for EXTRA Impact?*** If you're ready to find true fulfillment, strengthen your focus, and ignite your true potential, the Impact Theory subscription was created just for you.  *New episodes delivered ad-free, EXCLUSIVE access to hundreds of archived Impact Theory episodes, Tom AMAs, and so much more!* This is not for the faint of heart. This is for those who dare to learn obsessively, every day, day after day. *****Subscribe on Apple Podcasts: https://apple.co/3PCvJaz***** Subscribe on all other platforms (Google Podcasts, Spotify, Castro, Downcast, Overcast, Pocket Casts, Podcast Addict, Podcast Republic, Podkicker, and more) : https://impacttheorynetwork.supercast.com/ Learn more about your ad choices. Visit megaphone.fm/adchoices

Today, we embark on a journey deep into the realm of neuroinflammation, a pivotal factor influencing our mental and cognitive well-being. Joined by Dr. Austin Perlmutter, an esteemed internal medicine physician, and New York Times bestselling author, we delve into the intricate interplay between lifestyle choices and brain health.   Our discussion illuminates the profound impact of neuroinflammation on mood disorders, cognitive decline, and behavioral shifts. From identifying symptoms to understanding the underlying signals, we empower listeners with insights to recognize and address brain inflammation proactively.   Through practical strategies like mindfulness, dietary adjustments prioritizing gut health, and optimizing sleep quality for brain detoxification, we equip you with actionable steps to enhance cognitive vitality and mitigate the risk of neuroinflammatory diseases.   Join us as we unlock the secrets of optimal brain health, providing you with the knowledge and tools to nurture a healthier, happier brain. In This Episode: 00:00 Understanding Brain Inflammation: Symptoms and Signals   00:18 Welcome to Dr. Jocker's Functional Nutrition Podcast   02:44 Diving Deep into Neuroinflammation with Dr. Austin Perlmutter   13:53 The Gut-Brain Connection: Diet, Microbiome, and Health   19:16 Optimizing Health with Diet: Fiber, Polyphenols, and Organic Choices   27:18 Unlocking the Secrets of Sleep and Brain Health   27:39 The Glymphatic System: A Pathway to Brain Detox   29:20 The Critical Role of Sleep in Memory and Health   29:37 Addressing Sleep Apnea: Risks and Solutions   30:21 Lifestyle Tips for Better Sleep Quality   36:11 Creating a Sleep Sanctuary: Environment Matters   43:36 Stress and Its Impact on Brain Health   49:49 Final Thoughts on Brain Health and Well-being This podcast is sponsored by ShopC60.com. C60 is a powerful, Nobel Prize-winning antioxidant, that helps to optimize mitochondrial function, fights inflammation, and neutralizes toxic free radicals! I'm a big fan of using C60 in conjunction with your keto and intermittent fasting lifestyle to support your immune system, help your body detox, and increase energy and mental clarity. My favorite C60 products for Keto & IF lifestyles include C60 Purple Power in Organic MCT Coconut Oil (you can add this to your coffee) and their delicious Sugar-Free C60 Gummies (made with allulose and monk fruit)! If you are over the age of 40, and you'd like to kick fatigue and brain fog to the curb this year, visit shopc60.com and use the coupon code “JOCKERS” for 15% OFF  and start taking back control over your health today!     Looking for a nutritious snack to fuel your day? Look no further than Paleo Valley's grass-fed meat sticks! Packed with protein and healthy fats, these snacks are perfect for stabilizing your blood sugar and satisfying cravings. With no sugar additives or preservatives, you can enjoy guilt-free snacking anytime, anywhere.   Whether you prefer pasture-raised turkey or grass-fed beef, Paleo Valley has you covered with delicious options like original summer sausage, garlic summer sausage, teriyaki, and jalapeno. Plus, their meat sticks boast the ideal omega 6 to 3 ratio for keeping inflammation in check, along with powerful animal-based nutrients to support immune function, energy, and skin health.   Don't just take our word for it – try them out for yourself! Visit paleovalley.com/jockers today and save 15% on meat sticks and other Paleo Valley products.   “Inflammation tells your brain to withdraw from other people, to experience low mood, potentially even to be more aggressive towards other people.” -Dr. Austin Perlmutter   Subscribe to the podcast on: Apple Podcast Stitcher Spotify PodBean  TuneIn Radio   Resources:   Visit https://shopc60.com/jockers – Use code “JOCKERS” to get 15% off! Paleovalley's Meatstick - visit paleovalley.com/jockers    Connect with Dr. Austin Perlmutter: Website: https://austinperlmutter.com Book: https://amzn.to/49Kmnkq     Connect with Dr. Jockers: Instagram – https://www.instagram.com/drjockers/ Facebook – https://www.facebook.com/DrDavidJockers YouTube – https://www.youtube.com/user/djockers Website – https://drjockers.com/   If you are interested in being a guest on the show, we would love to hear from you! Please contact us here! - https://drjockers.com/join-us-dr-jockers-functional-nutrition-podcast/  

In today's episode of The Root Cause Medicine Podcast, we explore the often-overlooked importance of brain health and how it directly impacts our quality of life with Dr. Austin Perlmutter. You'll hear us discuss: 1. Brain inflammation 2. Brain-related conditions in women 3. Detoxification and brain health 4. Lifestyle choices supporting brain health 5. Supplements for brain health Dr. Austin Perlmutter is a board-certified internal medicine physician, a New York Times bestselling author, and a published researcher. He is also a health investor and international educator dedicated to helping people improve their health by addressing the biological roots of "stuckness" in the brain and body. Currently, Dr. Perlmutter serves as the executive director and research lead at Big Bold Health. Order tests through Rupa Health, the BEST place to order functional medicine lab tests from 30+ labs - https://www.rupahealth.com/reference-guide

Welcome back to the Evolving Wellness Podcast, my name is Sarah. Join Dr. Mark Sherwood and me as we delve into the holistic approach to health care, bridging his extensive background from law enforcement to naturopathic practice. We explore the limitations of traditional and functional medicine, advocating for an integrated model focused on patient welfare and the groundbreaking benefits of hydrogen therapy for inflammation and mitochondrial health. Our dialogue extends to the critical examination of dietary guidelines and processed foods' role in the prevalence of chronic diseases, highlighting the importance of ancestral diets and environmental influences like mold. This journey of discovery is further enriched by personal narratives, including my daughter's battle with neuroinflammation and the transformative effects of hydrogen inhalation therapy. This episode is an invitation to reevaluate health practices, embracing a holistic paradigm that nurtures the body's innate healing capacities. Holy Hydrogen - Inhalation & Hydrogen Water - code SARAHK - https://holyhydrogen.com/SARAHK Check Out Dr. Mark Sherwood Website Instagram Episode Keywords + Tags (YouTube) Health, Wellness, Functional Medicine, Hydrogen, Allopathic Medicine, Holistic Medicine, Naturopathy, Osteopathy, Health Insurance, Autoimmune Conditions, Mold, Environmental Toxins, Emotional Wellbeing, Mental Health, Cancel Culture, Alternative Medicine, Body Image, Body Positivity, Food Pyramid, Community, Informed Consent, Non Native EMFs, Resilience, Biological Age, Blue Zones, Mitochondria Dysfunction, Inflammation, Leptin, Peptides, Quick Fix, Nutrition, Leaky Gut, Free Radicals, Hydroxyl Radicals, Cortisol, Adrenal Glands, Stress, Digestion, Prevention, Avoidance, Heart Disease, Fear, Faith, Prayer, Alternative Healing The key moments in this episode are: 02:10 - Dr. Mark Sherwood's journey to being a Naturopathic Doctor 10:15 - Analyzing modern medicine 13:30 - Trusting the medical system 15:49 - Modern environmental disturbances 21:16 - Life begins when sperm fertilizes the egg 28:02 - Brain Inflammation and gut dysfunction 31:54 - Importance of Hydrogen 41:00 - Brain responses to environment 44:45 - Disease prevention and avoidance 49:11 - Healing yourself and the dangers of identifying with your diagnosis 58:44 - Hydrogen and best practices This video is not medical advice & as a supporter to you and your health journey - I encourage you to monitor your labs and work with a professional! ______________________________________ ⁠⁠⁠⁠Click here to get all my free guides and product recommendations to get started on your journey!⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠Check out all my courses to understand how to improve your mitochondrial health & experience long lasting health! (Use code PODCAST to save 10%)⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠Sign up for my newsletter to get special offers in the future!⁠⁠ Holy Hydrogen use code SARAHK

In this episode of the Dr. Jockers Functional Nutrition Podcast, Dr. Jockers welcomes repeat guest Dr. Peter Kan, an expert in integrative and functional medicine, to dive into the symptoms, root causes, and consequences of brain inflammation.    They explore the linkage between gut health and brain function, common symptoms of brain inflammation such as fatigue and brain fog, and the role of the gut-brain and brain-gut axes in overall health. Dr. Kan elaborates on autoimmunity's impact on the brain, the importance of addressing foundational health issues (like blood sugar and oxygenation), and key supplements that can aid in reducing brain inflammation, highlighting Omega-3 fatty acids, glutathione, vitamin D, turmeric, and resveratrol.    The discussion also covers the concepts of neuroplasticity and the importance of lifestyle factors like diet and exercise in maintaining a healthy brain. Dr. Jockers emphasizes the potential for brain healing and improvement in quality of life regardless of the starting point.   In This Episode: - Diving Deep into Brain Inflammation with Dr. Peter Kan - Understanding Brain Inflammation: Symptoms, Causes, and Effects - Exploring the Root Causes of Brain Inflammation - The Gut-Brain Connection: How Gut Health Influences Brain Inflammation - Autoimmunity and Brain Inflammation: Unveiling the Link - Understanding Oral Tolerance and Autoimmunity - The Brain's Role in Autoimmunity and Inflammation - The Path to Neurological Autoimmunity and Its Consequences - Exploring Neuroplasticity and Strategies for Brain Health - Roadmap to Reducing Brain Inflammation and Supporting Neuroplasticity - Supplements for Reducing Brain Inflammation - Closing Thoughts: Foundations for Brain Health This podcast is sponsored by ShopC60.com. C60 is a powerful, Nobel Prize-winning antioxidant, that helps to optimize mitochondrial function, fights inflammation, and neutralizes toxic free radicals!   I'm a big fan of using C60 in conjunction with your keto and intermittent fasting lifestyle to support your immune system, help your body detox, and increase energy and mental clarity.    My favorite C60 products for Keto & IF lifestyles include C60 Purple Power in Organic MCT Coconut Oil (you can add this to your coffee) and their delicious Sugar-Free C60 Gummies (made with allulose and monk fruit)!   If you are over the age of 40, and you'd like to kick fatigue and brain fog to the curb this year, visit shopc60.com and use the coupon code “JOCKERS” for 15% OFF  and start taking back control over your health today!     Have you heard of Paleovalley's amazing Turmeric Complex? It contains whole food and organic turmeric instead of just isolated curcumin.    And we know that organic turmeric is way better, and one of the best things you can take to shut down inflammation in the body and support healthy blood flow and blood pressure.    It also includes coconut oil and black pepper as its ingredients, which has been shown to improve the absorption of turmeric by 2000%! Plus, there's also organic ginger, rosemary, and cloves which synergize with the turmeric to help improve digestion and blood sugar.   Paleovalley's Turmeric Complex also supports joint health, mental clarity, and improved brain function. You've just got to try this product. Visit paleovalley.com/jockers!   “Inflammation is a natural response. It's an immune response that your body uses to either try to get rid of a pathogen or try to clear up cellular debris" - Dr. Jockers   Subscribe to the podcast on: Apple Podcast Stitcher Spotify PodBean  TuneIn Radio   Resources: Visit https://shopc60.com/jockers - Use code “JOCKERS” to get 15% off! Paleovalley's Turmeric Complex- visit paleovalley.com/jockers    Connect with Dr. Kan: - Website - https://askdrkan.com/   Connect with Dr. Jockers: Instagram – https://www.instagram.com/drjockers/ Facebook – https://www.facebook.com/DrDavidJockers YouTube – https://www.youtube.com/user/djockers Website – https://drjockers.com/ If you are interested in being a guest on the show, we would love to hear from you! Please contact us here! - https://drjockers.com/join-us-dr-jockers-functional-nutrition-podcast/  

Do you ever feel like no matter what you do, you always end up with the same result? In this episode, we're talking with Ashok Gupta about neuroplasticity and how we can retrain our brains to get healthier. He shares how we can manage conditions like fibromyalgia, chronic fatigue, and mold illness in a way that traditional healthcare often overlooks.Ashok Gupta is an internationally renowned Speaker, Filmmaker & Health Practitioner who has dedicated his life to supporting people through chronic illness, and achieving their potential. Ashok suffered from ME, or Chronic Fatigue Syndrome, around 25 years ago when he was studying at Cambridge University. Through neurological research that he conducted, he managed to get himself 100% better. He then set up a clinic to treat others, and then published the well-known neuroplasticity “limbic retraining” recovery program and app known as the Gupta Program in 2007. He has published several medical papers, including randomized controlled trials on Long Covid, ME/CFS, and fibromyalgia, showing that the treatment is effective, and he is continually researching these conditions.Connect with Ashok GuptaGupta ProgramInstagramYouTubeIn this episode, you'll learn more about...How neuroplasticity impacts your healthImportance of addressing the root cause of neuroimmune conditions for long-term healingPractical strategies to blend brain retraining with other therapies to optimize treatment Thank you to Purity Woods for sponsoring this episode!Purity Woods is currently offering 17% off sitewide, but we have an additional 10% discount for our listeners for a total savings of 27%!Go to puritywoods.com/LEAH or enter code LEAH at checkout for an additional 10% off your first order.Thank you to Veri for sponsoring this episode!Use code VSM-LEAH to save $30 on your continuous glucose monitor from VeriJoin the Eversio Wellness Mushroom Giveaway!2 ways to win a functional mushroom set:Rate and review the podcast on AppleOR Share an episode to your IG stories and tag me @leah_brueg or @balancinghormonesnaturallyThank you to Eversio Wellness for partnering with us!Use code LEAH for 15% off at Eversio.....Leah's favorite productsWork with Leah Join our private facebook group Balancing Hormones NaturallyFollow us on Instagram @balancinghormonesnaturally The recommendations presented in this podcast are not a substitute for medical advice from a qualified doctor. Before making any changes to your diet and lifestyle, please consult with your health care provider. Some of these links contain affiliate links. Hosted on Acast. See acast.com/privacy for more information.

The last newsletter, I addressed how our hormonal stress response can trigger mast cells and microglial cells, thereby interfering with neuronal communication in the brain and causing symptoms. Such symptoms can include brain fog, fatigue, depression, anxiety, mood swings and, for some, hallucinations. We live in a world that is increasingly inflammatory - more toxins, more insults to our microbiome, and more insults to our sense of self from marketing and media. Add to this the reality that many things that lower our stress response and thus inflammation, are being diminished - less human connection, less silence, solitude, stillness and time in the natural world. But, we have choices. Supporting our brain and well-being is really about getting back to the basics of our humanity and getting back to the things most of us long to do anyway. We can approach the below list with an openness to ideas (of which one or two may resonate) ...or we can approach it like a to-do list - one that reinforces the notion that we need to fix ourselves to be worthy. My hope is the former. We're already worthy and deserving of feeling healthy. This list will generally move in the direction of what I think most of us can benefit from (1-3), additional considerations that may be helpful for those with brain symptoms (4-7) and, lastly, I've included tools for those who are dealing with very high immune reactivity and/or mast cell activation syndrome (8-10). This list will not be complete. Perhaps you'll share what is helpful for you. To receive the newsletter (text and audio) in your mailbox each week, subscribe at: https://www.courtneysnydermd.com or on Substack at: https://www.courtneysnydermd.substack.com Medical Disclaimer: This newsletter is for educational purposes and not intended or implied to be a substitute for professional medical advice, diagnosis or treatment for either yourself or others, including but not limited to patients that you are treating (if you are a practitioner). Consult your own physician for any medical issues that you may be having. Get full access to Holistic Psychiatry at courtneysnydermd.substack.com/subscribe

In this episode, I'll break down the key players in brain inflammation, how these players work together, and how they can ultimately disrupt neuronal communication.  I'll discuss:* The beneficial role of inflammation.* The bridge between the brain and immune system - mast cells & microglial cells.* The bridge between the immune system and our hormonal stress response - Corticotropin Releasing Hormone (CRH).* How head injury, toxicity, problematic microbes, and emotional and psychological stress contribute to brain inflammation.With this groundwork laid, in an upcoming newsletter, I'll discuss the many ways we can lower inflammation in the brain.To receive the newsletter (text and audio) in your mailbox each week,subscribe at: https://www.courtneysnydermd.com oron Substack:Medical Disclaimer:This newsletter is for educational purposes and not intended or implied to be a substitute for professional medical advice, diagnosis or treatment for either yourself or others, including but not limited to patients that you are treating (if you are a practitioner). Consult your own physician for any medical issues that you may be having. Get full access to Holistic Psychiatry at courtneysnydermd.substack.com/subscribe

On this special episode of Vitality Radio, Jared interviews Liz Wilner, the creator of OpenVAERS.com. Liz developed the OpenVAERS website for herself after her daughter developed PANS/PANDAS from the chicken pox vaccine. Liz shares her inspiring story of how her daughter was able to heal from this form of brain inflammation naturally and without medical intervention. You'll learn how and why OpenVAERS was created and how you can use it to easily browse and search reports in the Health and Human Services and CDC's own VAERS (Vaccine Adverse Event Reporting System) database. Additional Information:OpenVAERSVAERS (Vaccine Adverse Events Reporting System - please report injuries)React19 - Science-based support for people suffering from long-term COVID-19 vaccine effectsDearly Discarded Podcast Episode 31: Brianne Dressen and Joel Wallskog: How React19 is Fighting For the Injured#183 VR Special: The Reality of Being Vaccine Injured by the COVID19 Vaccine with Brianne Dressen#181 VR Special: Understanding Informed Consent and Vaccinations with Dr. Paul Thomas#272: Turtles All The Way Down, Science and Myth with Zoey O'Toole and Mary Holland#270: Del Bigtree: Whose Interests are American Health Agencies Really Protecting?Visit the podcast website here: VitalityRadio.comYou can follow @vitalityradio and @vitalitynutritionbountiful on Instagram, or Vitality Radio and Vitality Nutrition on Facebook. Join us also in the Vitality Radio Podcast Listener Community on Facebook. Shop the products that Jared mentions at vitalitynutrition.com. Let us know your thoughts about this episode using the hashtag #vitalityradio and please rate and review us on Apple Podcasts. Thank you!Please also join us on the Dearly Discarded Podcast with Jared St. Clair.Just a reminder that this podcast is for educational purposes only. The FDA has not evaluated the podcast. The information is not intended to diagnose, treat, cure, or prevent any disease. The advice given is not intended to replace the advice of your medical professional.

Anxiety. Trouble sleeping. Feeling like you can't focus. These are probably the top 3 complaints I hear in my practice. But what is the common thing all of these symptoms have in common? They may all be stemming from your brain!  Today, my guest, Dr. Romie Mushtaq and I will be diving into how to know if your brain is the reason for your health issues, the quiz she created that may give you some insight into if you have a “busy brain” or not, and the steps you can take to heal your brain! You will hear:Why you are NOT alone in feeling burnt outSolutions for your busy brain that are beyond “berries and breathing”The main 3 symptoms high performing people experienceWhy healing the neuroinflammation in your brain is key to thrivingAnd more!!More about Dr. Romie:Dr. Romie Mushtaq is a board-certified physician, award-winning wellness speaker, and the founder of “brainSHIFT at Work.” She brings together over 20 years of authority in neurology, integrative medicine, and mindfulness to not just deliver programs, but create cultural change.She is on a mission to transform mental health and wellness in the workplace and currently works with Fortune 500 companies, professional athletes, & global associations. Dr. Romie is also the Chief Wellness Officer for Evolution Hospitality, where she scaled a mindfulness & wellness program to over 7000 employees. Her expertise is featured in the national media such as NPR, NBC, TED talks, and Forbes. Find the cure for your busy brain at drromie.com or @drromie on social media.Connect with Dr. Romie:Busy Brain Quiz: https://drromie.com/busy-brain-test/Busy Brain Cure (book): https://drromie.com/book/Dr. Romie's Website: https://drromie.com/LinkedIn: https://www.linkedin.com/in/drromie/Twitter: https://twitter.com/DrRomieInstagram: https://www.instagram.com/drromie/Facebook: https://www.facebook.com/DrRomieYouTube: https://www.youtube.com/channel/UC05grQ3WOYK_BX7hxTIvt7w ?view_as=subscriberThe book you need to truly transform yourself in 2024 is here! Fast to Faith: A 40-Day Awakening. Reconnect Your Body, Mind, and Soul For Lasting Weight Loss, Sustained Energy, and Unstoppable Strength! AND receive all the awesome BONUSES for being a quick-starter!See ya soon- GOD BLESS YOU!!!Struggling with balancing your hormones? Grab your copy of the The Gutsy Gynecologist's Guide to Balancing your Hormones: https://drtabatha.com/free-guide/Support your hormone balance- EnergyLift! Connect with Dr. Tabatha:Work with us: Schedule a callDr. Tabatha's Facebook: https://www.facebook.com/DrTabathaDr. Tabatha's IG: https://www.instagram.com/thegutsygynecologist/Dr. Tabatha's YouTube: https://www.youtube.com/channel/UCWea1x1abLERehb5yn_nfow

In this episode, Dr. Andy Wong talks about the importance of brain health, including how physical and mental health are connected, the effects of alcohol consumption on cognitive decline, and how to take proactive measures to protect brain health. They dive into: 1. No brain, no gain 2. What is an inflamed brain? 3. What causes brain inflammation? 4. The root cause of depression 5. Dr. Andy Wong's practical advice Dr. Andy Wong is a board-certified internal medicine doctor trained in integrative and functional medicine. He specializes in investigating the root cause of health issues and working with patients to optimize their health and wellness. Dr. Wong is trained in the Bredesen protocol for the reversal of cognitive decline and is also specialized in acupuncture, functional medicine, and nutrition. Order tests through Rupa Health, the BEST place to order functional medicine lab tests from 30+ labs - https://www.rupahealth.com/reference-guide

Welcome to Episode 187 of Autism Parenting Secrets. Today we are focusing on what a parent like you can do about FLARES.These are sudden onsets of symptoms with your child.Our guest is Dr. Lindsey Wells.  She is a naturopathic physician located in Wilton, Connecticut. She focuses her practice on pediatric integrative care for PANS/PANDAS, Autism Spectrum Disorder, Tickborne Diseases, and other neurodevelopmental disorders. She is the Past President of the Connecticut Naturopathic Physicians Association and is a Fellow of the Medical Academy of Pediatric Special Needs. She frequently lectures on PANS/PANDAS and ASD to both professional and parent organizations and is the author of the children's book Super Sam and the Battle Against PANS/PANDAS. The secret this week is These Factors Fuel FLARESYou'll Discover:What Exactly is PANS/PANDAS (5:51)How To Spot FLARES (8:34)A Surprising Major Cause of Brain Inflammation (14:31)How Antimicrobial Herbals Help (22:29)The Impact of Seasonal Allergies (30:00)About Our GuestDr. Lindsey Wells is a naturopathic physician located in Wilton, Connecticut. She focuses her practice on pediatric integrative care for PANS/PANDAS, Autism Spectrum Disorder (ASD), Tickborne Diseases, and other neurodevelopmental disorders. Also, she cares for the parents of her pediatric patients, which allows for a comprehensive model of care for the whole family. She is the immediate Past President of the Connecticut Naturopathic Physicians Association (CNPA) and is a Fellow of the Medical Academy of Pediatric Special Needs. She frequently lectures on PANS/PANDAS and ASD to both professional and parent organizations and is the author of the children's book Super Sam and the Battle Against PANS/PANDAS. Also, she is the creator of the Well-Minded Mommas Club, a community for mothers of children with complex medical illnesses.https://lindseywellsnd.com/References in The Episode:https://aspire.care/Additional Resources:Take The Quiz: What's YOUR Top Autism Parenting Blindspot?To learn more about Cass & Len, visit us at www.autismparentingsecrets.comBe sure to follow Cass & Len on Instagram

We are so very honored to have Dr. Apigian on the podcast. Dr. Aimie Apigian, MD, MS, MPH is a double board-certified physician with 2 Master's Degrees in Biochemistry and Public Health and is the leading medical expert on stored trauma in the body. She bridges the worlds of functional medicine and trauma therapy to help accelerate the trauma healing journey through her framework and protocols addressing The Biology of Trauma™. Topics: 1. Childhood Attachment and Neurodevelopment - Definition of childhood attachment - Relationship between attachment and neurodevelopment - Role of attachment in shaping future well-being 2. Biological Aspects of Childhood Attachment and Trauma - Explanation of the biological aspects of childhood attachment - Exploration of the biological aspects of childhood trauma 3. Dysregulation of the Nervous System - Factors contributing to nervous system dysregulation - Impact of toxins, environmental stressors, and gut stress on the nervous system 4. Lowering Toxins for Trauma Management - How reducing toxins in the body can help manage trauma - Strategies for lowering toxins within the body 5. Lowering Brain Inflammation - Methods to lower brain inflammation - The role of NAC (N-Acetyl Cysteine) and Magnesium Threonate, including dosage considerations 6. Practical Tools for Healing - Emphasis on practical tools and hope in the healing process - Sharing of specific practical tools individuals can apply to their healing journey Thanks for tuning in! Get Chloe's Book Today! "⁠⁠⁠⁠⁠⁠⁠⁠⁠75 Gut-Healing Strategies & Biohacks⁠⁠⁠⁠⁠⁠⁠⁠⁠" If you liked this episode, please leave a rating and review or share it to your stories over on Instagram. If you tag @synthesisofwellness, Chloe would love to personally thank you for listening! Follow Chloe on Instagram ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@synthesisofwellness⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Follow Chloe on TikTok @chloe_c_porter Visit ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠synthesisofwellness.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ to purchase products, subscribe to our mailing list, and more! Or visit ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠linktr.ee/synthesisofwellness⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ to see all of Chloe's links, schedule a BioPhotonic Scanner consult with Chloe, or support the show! Thanks again for tuning in! --- Support this podcast: https://podcasters.spotify.com/pod/show/chloe-porter6/support

In this episode of the Biology of Trauma podcast, I will be discussing the role of neuroplasticity in trauma and how it can either keep you stuck or move you forward. We live in a world that glorifies neuroscience and neuroplasticity, so the big question we are going to answer today is: How can you use neuroplasticity to help you on your healing journey?   We will look at client experiences and see how those may apply to you. In my teachings, we will talk about why neuroplasticity isn't necessarily the place to start healing, especially if we have not first regulated our system. We will touch on dealing with brain inflammation, getting the right amounts of serotonin and other neurotransmitters in our system, and finding the pattern of the nervous system.   Key Takeaways: Why it is essential to know how long or chronic a pattern is Understanding time and neuroplasticity Why both gentleness and firmness are needed to address stored trauma How to shift from negative to positive neuroplasticity   Links for this episode: Brain Inflammation Protocol: https://us.fullscript.com/welcome/aapigian/store-start?signup_source=shareable_protocol&source=shareable_protocol&source_record=VHJlYXRtZW50UGxhblRlbXBsYXRlLTczNTc4 Mag Calm: https://www.traumahealingaccelerated.com/product/magnesium-calm/ Foundational Journey (to lay the foundation of regulation): https://traumahealingaccelerated.mykajabi.com/21-Day-Journey-and-All-Parts-of-Me   GUIDE “How do you know if you have trauma? And if you do have trauma, what is the next step? The good news is, there is a step-by-step process for identifying and healing trauma. Download my step-by-step guide (with a quiz inside!) to see if you have trauma and to identify how to get started. Download your free roadmap here: https://traumahealingaccelerated.mykajabi.com/steps-to-identify-and-heal-trauma-a-roadmap-for-healing”   –BIO– Find More About Dr.Aimie https://www.traumahealingaccelerated.com/dr-aimie-apigian-md-ms-mph/ Disclaimer: By listening to this podcast, you agree not to use this podcast as medical advice to treat any medical condition in either yourself or others. Consult your own physician for any medical issues that you may be having.  This entire disclaimer also applies to any guests or contributors to the podcast. Under no circumstances shall Trauma Healing Accelerated, any guests or contributors to The Biology of Trauma podcast, or any employees, associates, or affiliates of Trauma Healing Accelerated be responsible for damages arising from the use of the podcast.   Helpful links: Guide for Biochemical Imbalances in Mental Health Foundational Journey for Addressing Stored Trauma We Recommend: Starters Basic Bundle for Energy - This provides your body with key essentials that can help get you unstuck, have deeper, more restorative sleep, and enhance your energy levels. https://www.traumahealingaccelerated.com/product/starters-basic-bundle-for-energy/  

In today's episode with Dr. Gary Kaplan, you'll hear us take a deep dive into: 1. Autoimmune diseases and chronic illnesses 2. The impact of chronic inflammation on the brain and body 3. The role of sleep in brain health 4. PANS, PANDAS, and POTS 5. How to find a doctor that listens to your symptoms Dr. Gary Kaplan is the founder of Kaplan Center for Integrative Medicine, specializing in the treatment of chronic pain for over 25 years, and the author of "Total Recovery: A Revolutionary New Approach to Breaking the Cycle of Pain and Depression" and "Why You Are Still Sick, How Infections Can Break Your Immune System & How You Can Recover." Dr. Kaplan is also board-certified in Medical Acupuncture and has studied and practiced Osteopathic Manipulative Medicine, Regenerative Medicine, and Emergency Medicine. Order tests through Rupa Health, the BEST place to order functional medicine lab tests from 30+ labs - https://www.rupahealth.com/reference-guide

In this episode of The Root Cause Medicine Podcast, we discuss neuropsychiatric symptoms, brain health, brain inflammation, head trauma, and neurodegenerative conditions. They dive into: 1. Inflammation Root Causes 2. Traumatic Brain Injury and Psychological Processes 3. HYLANE Technology Dr. Robert Hedaya is a Clinical Professor of Psychiatry at Georgetown University Medical Center. He is a neuropsychiatrist that teaches functional medicine, psychiatry, brain health, brain inflammation, head trauma, and neurodegenerative conditions, and the founder of The Whole Psychiatry & Brain Recovery Center. Dr. Hedaya also wrote several books, including Understanding Biological Psychiatry, The Anti-depressant Survival Program, and Depression: Advancing the Treatment Paradigm. Order tests through Rupa Health, the BEST place to order functional medicine lab tests from 30+ labs - https://www.rupahealth.com/reference-guide

We don't have to fear Alzheimer's and cognitive decline like generations before us. Thanks to dedicated researchers and doctors like today's guest, we know why Alzheimer's happens – and how to prevent it.Dr. Dale Bredesen received his undergraduate degree from Caltech and his medical degree from Duke University. In 2013, he returned to UCLA as the director of the Easton Center for Alzheimer's Disease Research. The Bredesen Laboratory studies the basic mechanisms underlying the neurodegenerative process and the translation of the knowledge into effective therapies for Alzheimer's disease. He has published over 230 papers and has written two New York Times bestselling books, The End of Alzheimer's: The First Program to Prevent and Reverse Cognitive Decline, and The End Of Alzheimer's Program. In today's episode, he fills us in on everything he knows about how to protect your brain from this disease, what Alzheimer's is, how we can reverse and prevent it, and blood tests that can indicate our odds of getting it. Dr. Bredesen is a beacon of hope for so many of us and for families that have been affected by this disease. Knowing that we have the tests to catch early signs of cognitive decline and can harness the power of the Bredesen Protocol to fight inflammation through diet and lifestyle changes in our earlier years means that we can end Alzheimer's.We also cover…(00:01:53) Preventing Alzheimer's(00:06:56) The 4 Stages of Alzheimer's(00:16:12) Understanding the Root Cause of Alzheimer's(00:22:40) Alzheimer's Testing 101(00:25:52) Addressing the Glucose Energetic Emergency(00:30:48) The Bredesen Protocol: Diet Recommendations To Prevent Alzheimer's(00:38:36) What Leads to Brain Inflammation & How To Identify It(00:47:12) Why Alzheimer's Is a Women Centric Disease(00:50:22) Best-in-Class Methods for Reducing Brain InflammationThis episode is brought to you by:BWBK Protein Powder | Get $10 off your order with PODCAST10 at bewellbykelly.com.Cozy Earth | Get 35% off site wide when you use the code BEWELL at CozyEarth.com.MasterClass | This holiday season, give one annual membership and get one free at masterclass.com/bewell. Resources:Click here for full show notesRead: The End of Alzheimer's by Dr. Dale BredesenRead: The End of Alzheimer's Program by Dr. Dale BredesenWebsite:

Which common infection is associated with frailty in older adults? Find out about this and more in today's PV Roundup podcast.

In this special compilation episode, we put together the most helpful information we received on holistic treatments from the 3 experts we had previously on our podcast. This episode includes topics on:- nutrition- brain inflammation- genetic epigenetic mismatch - 4 foods to avoid- toxicity- and more!You can listen to the original episodes below:Providing a Roadmap for Neurodevelopmental Disorders with Maria Rickert Honghttps://www.mothersguidethroughautism.com/podcast/episode-46Functional Medicine Approach to Autism with Dr. Will Colehttps://www.mothersguidethroughautism.com/podcast/episode-42Toxic Factor in Autism and Working with Homotoxicology with Mary Coylehttps://www.mothersguidethroughautism.com/podcast/episode-47Enjoy!Purchase my book A Mother's Guide Through Autism:https://amothersguidethroughautismbook.com/bookSign up to get news and updates from me: https://www.mothersguidethroughautism.comTheme song: Look at the Clouds by Tristan Lohengrinhttps://soundcloud.com/tristanlohengrin/look-at-the-clouds

Dr Redd is a research biologist, a graduate of naturopathic medical school and owns 8 clinics that focus on helping patients from around the world with autoimmune and inflammatory conditions called RedRiver Health and Wellness. His clinics see hundreds of patients a day from around the world. He has 12 years of post graduate school ranging from nutrition, alternative health care and public health biology at Johns Hopkins. He is starting his stem cell and regenerative medicine residency and will soon be opening a regenerative medicine clinic. In today's episode, Dr. Josh Redd and I discuss all about brain inflammation and how it affects kids' health. We dive into how kids diet and lifestyle choices are the main factor for their health issues. We talk about how blood sugar imbalances and gluten can affect kids' mood. Dr. Redd's Instagram Page: https://www.instagram.com/drjoshredd/?hl=en Dr. Redd's Youtube Page: https://www.youtube.com/@drjoshredd Dr. Redd's Website: https://drjoshredd.com/ RedRiver Health & Wellness Website: https://www.redriverhealthandwellness.com/ For 10% off you order at Mett Naturals Use Code JUSTINGREDIENTS at https://mettnaturals.com/

We are thrilled to bring you this fascinating conversation with Dr. John Lieurance about different powerful biohacks which include high-dose melatonin and methylene blue supplementation. We dive into the different uses of melatonin (other than sleep regulation!) and how it can be a game-changer for those struggling with chronic health conditions. He also shares his personal experience with methylene blue, the importance of the "blue spot" in the brain, the role of neuroinflammation and neuroprotection, as well as how to dose it. Make sure you have a notepad nearby for this episode because you'll definitely want to take notes!John A. Lieurance, ND, DC, DABCN (board eligible) is an Author, Physician, Lecturer, Scientific Advisor for MitoZen.com, and educator to those seeking vitality, longevity, and enhanced consciousness. His interest is in connecting what he calls, "The 3 legs of a stool": Vitality of the body, Mind Mastery & a Direct experience of God. Using science and ancient wisdom, he aims to connect these dots in his own journey to becoming the best version of himself in this life.Diving deeply into many healing methods, to discover the deepest and most profound means to activate cellular energy, such as with Melatonin, Methylene Blue, and NAD+ as well as Fasting with various nutrients to activate responses. Dr. John explores many new paths in the healthcare world, with his unique & fresh ideas using various delivery systems, such as suppositories and nasal sprays, and various protocols he has created.He attended Parker College of Chiropractic & received his Naturopathic degree in 2001 from St. Luke's School of Medicine. He has practiced Functional Neurology, Naturopathic medicine, and Regenerative Medicine, using stem cell therapy in Sarasota for 25 years.Founder of the Advanced Rejuvenation Center in Sarasota, Florida, and founder of Functional Cranial Release - which is an Endo-Nasal Cranial Treatment with the ability to unlock the spinal fluid to allow profound healing of the nervous system.See his next book "It's All in Your Head: Endo-Nasal Cranial Therapy". Dr. Lieurance has been involved in multiple clinical trials including an investigation into the use of stem cells for Parkinson's Disease, COPD, and OA of the knee and hip from 2012-2014. He has a clinical focus on mold illness, Lyme disease, and chronic viral infections. Using natural eastern and Western approaches to healing the true source of disease, which lies in the metabolic pathways that are challenged by chronic inflammation resulting in infections and toxicity.Books Authored:Melatonin: Miracle Molecule - Melatonin Miracle Molecule: Transform your life with Melatonin. Why higher doses are safe and benefit beyond sleep as the bodies master stress resilience molecule for healing & longevity.Ebook: Methylene Blue: Silver Bullet - (See MethyleneBlueBook.com)It's All in Your Head: EndoNasal Cranial Therapy – It's All In Your Head: Endo Nasal Cranial TherapySHOW NOTES:0:51 Welcome to the show!1:27 Pop Quiz of the Day3:18 Today's episode5:53 Dr. John Lieurance's bio6:52 Welcome him to the show!8:49 Intro to Melatonin10:35 Energy for inflammation12:14 When do we need melatonin?14:35 Super-Physiological doses15:18 Renee's experience with EBV & Melatonin16:04 Metabolizing melatonin & genetics17:29 Taking melatonin during the day18:20 Best practices for dosing19:56 First studies on melatonin21:53 Cell Danger Response23:05 Activating our circadian rhythm24:32 The Blue Spot 26:18 Perseveration & Rumination29:10 Brain inflammation, LPS & Trigeminal Nerve31:40 Blue Spot & Methylene Blue34:33 *Sleep Breakthrough*36:50 The body's stress response & Microglial cells41:57 Neuroprotection & “Fast Track Fast”45:10 Methylene Blue before HBOT47:26 Our experiences with Methylene Blue49:00 Dosing & Titrating Methylene Blue55:49 Combining color therapy with MB58:05 Nutrients for micro & macro dosing1:00:25 Serotonin Storm1:04:24 His final piece of advice1:06:39 Where to find himRESOURCES:Advanced Rejuvenation: Stem Cell Treatment,PRP Treatment,Prolotherapy , Ozone - Sarasota, FL MitoZen.Club  MitoZen ScientificIG: Your Out of Box DocFacebook: John LieuranceSleepbreakthrough.com/biohackerbabes - code: biohackerbabes10Support this podcast at — https://redcircle.com/biohacker-babes-podcast/donationsAdvertising Inquiries: https://redcircle.com/brands