Podcasts about cvd

Screening, evaluation, and CVD risk assessment

Elevated Lipoprotein(a) or Lp(a) is increasingly recognized as a significant, independent risk enhancer for cardiovascular disease (CVD). This course explores the evolving landscape of Lp(a) in clinical practice, emphasizing the importance of Lp(a) testing in comprehensive cardiovascular risk assessment. The safety and efficacy of current and emerging lipid-lowering therapies, with a focus on novel agents targeting Lp(a) reduction will be examined.  Claim CE and MOC credits: https://bit.ly/4r1xjU6

The FiltrateJoel Topf‍ ‍@kidneyboy.bsky.social‬Sophia Ambruso @sophia-kidney.bsky.socialNayan Arora @captainchloride.bsky.socialSpecial Guests Brian Rifkin @brianrifkin.bsky.socialAnna Gaddy @AnnaGaddyEditing and Show Notes byJoel TopfThe Kidney Connection written and performed by Tim YauShow NotesBrian Rifkin and Cristina Popa ascend to co-editors in chief of NephJC.Paresh Jadav receives the first NephJC Champion award. Dr. Jadav hosted the NephJC night and saved NephJC thousands of dollars. It makes a huge difference in our fund raising. Thank you.Also a big thank-you to Jade Teakell for buying the cowboy hats!The first pick of the draft, by Sophia is Fish oil for dialysis: Fish-Oil Supplementation and Cardiovascular Events in Patients Receiving Hemodialysis (NEJM)The second pick, by Brian is FINE-ONE (Bayer Press release)Rajiv Agarwal's mediation analysis to show how much of finerenone's beneficial renal effects are captured by the reduction proteinuria: Impact of Finerenone-Induced Albuminuria Reduction on Chronic Kidney Disease Outcomes in Type 2 Diabetes : A Mediation Analysis (PubMed)Anna has the third pick and it goes to Katherine Tuttle and the REM0DEL Trial: REMODELing mechanistic trials for kidney disease: a multimodal, tissue-centered approach to understand the renal mechanism of action of semaglutide (Science Direct)Nayan goes off-board and picks a poster by a med student (backed by Testani)Mechanism and Effects of Manipulating Chloride Homeostasis in Stable Heart Failure (ClinicalTrials.gov)For the final pick in the draft Joel went with a little Lilly on Lilly violence: Tirzepatide vs. Dulaglutide Is Associated with Reduced Major Kidney Events in Patients with Type 2 Diabetes, CVD, and Very High-Risk Kidney Diseases (JASN)Bring out your dead…What's left on the draft board.Liberate-D A Conservative Dialysis Strategy and Kidney Function Recovery in Dialysis-Requiring Acute Kidney Injury: The Liberation From Acute Dialysis (LIBERATE-D) Randomized Clinical Trial (JAMA)Atacicept for IgAN A Phase 3 Trial of Atacicept in Patients with IgA Nephropathy (NEJM)Lilia Cervantes crushed it with Community Health Worker Support for Hispanic and Latino Individuals Receiving Hemodialysis: The Navigate-Kidney Randomized Clinical Trial (JAMA)Tubular SecretionBrian: Late Breaking and High Impact Clinical Trials. Including Sibe! REGENCY Biopsy Data.Sophia: Flying Home. No, really it's the Electrolyte QuizJoel: The Poster Session, the Quiz Session, and Nayan: Flying to AHA to talk about dual-heart-kidney-transplantAnna: Kidney STARS! and Melanie Hoenig's session on potassium

JACC's November 25, 2025 issue kicks off Thanksgiving week with JACC Editor-in-Chief Harlan M. Krumholz, MD, SM, reflecting on his editor's page and the day he became a doctor (0:12).  For original research articles, he discusses a study on colchicine & clonal hematopoiesis, an exploratory study of the LoDoCo2 trial (1:10), and a paired editorial comment with more perspectives and a reminder of the upcoming COLCOT trial (4:33). Next, a study on Lp(a) and IL-6 (4:54) and an editorial (6:12), 30-year CVD risk percentiles based on the PREVENT equations (6:30), and an accompanying editorial from JACC Deputy Editor Erica Spatz, MD, on next-generation strategies to encourage healthier behaviors (7:35).  Other studies and editorials include a fascinating look at alcohol and blood pressure (8:04) and reinforcing the WHO public health guidance (10:05); remnant cholesterol in young adults (10:38) and implications for cholesterol guidelines (12:36). We also include four brief reports on RSV vaccine (13:11), long Covid (13:43), Lp(a) levels (14:06), the predictive power of polygenic risk scores (14:58), a viewpoint on US veterans (15:36), and our regular Amara Yad image (15:53), which we're delighted to be able to continue to promote with JACC: Clinical Electrophysiology Editor-in-Chief Kalyanam Shivkumar, MD.  

Screening, evaluation, and CVD risk assessment Medical science has finally recognized the link between chronic, low-grade inflammation and cardiovascular disease! In this episode of Live Foreverish, Dr. Mike and Dr. Crystal share the details on the latest guidelines published by the Americal College of Cardiology which provides action forward steps you can take today to detect and decrease your risk of having a heart attack or stroke. #LELearn #EDULiveforeverish

In episode 610, Jamie and James chat with Jennifer Young about yet another Vitamin D Tools for Practice. We look at what happens to mortality, CVD and cancer when Vitamin D supplements are compared to placebo. The results may surprise you – or maybe not if you have listened to previous BS Medicine Podcasts on this seemingly never-ending topic. Show Notes Tools For Practice Vitamin D and Mortality – Don't bet your life on it! Vitamin D and Respiratory Tract Infections: Does the sun's vitamin chase the cold?

In this solo episode, Darin reframes one of the most misunderstood forces in life — stress. Instead of seeing it as the enemy, he explores how stress is actually a messenger, guiding you back to alignment, safety, and awareness. Through science, spirituality, and lived experience, Darin breaks down how stress shows us where we're trying to control, where we're disconnected, and where our nervous system is calling for attention. He unpacks the layers of modern stress — from trauma and environment to community and purpose — and offers practical, embodied tools to restore calm, clarity, and resilience.     What You'll Learn 00:00:00 – Welcome to Super Life: Solutions for a Healthier Life and Better World 00:00:32 – Sponsor Spotlight: TheraSauna - Natural Healing Technologies (15% off with code Darrandai) 00:02:10 – The Super Life Podcast: Finding Contentment, Happiness, and Purpose 00:02:51 – Today's Topic: Stress - Reframing Stress as an Ally and Dashboard Light 00:04:54 – The "No Choice" Universe: Reconnecting to Infinite Possibilities 00:05:16 – The Reality of Stress: Statistics and the Impact of Chronic Stress 00:06:21 – Stress is Layered: Beyond a Single Cause, Addressing Chronic Stress 00:08:29 – Solutions for a Super Life: Safety over Calm and the Vagal Response 00:09:38 – The Inner Dialogue Layer: Trauma, Unconsciousness, and Spiritual Bypassing 00:11:47 – The Social Field Layer: Relationships, Community, and Finding Your Way Home 00:14:20 – Sponsor Spotlight: Bite Toothpaste - Sustainable, Non-Toxic Tabs (20% off with code Darin20) 00:16:35 – Creating Your Own Vision: Setting Boundaries with Media and Social Algorithms 00:17:29 – Finding Your Purpose: From Raising Children to Healing Injuries 00:18:35 – Environmental and Existential Stress Layers: Clutter, Noise, and Service 00:19:26 – Stress Load and Resiliency: Why Small Triggers Cause Blow-Ups 00:20:02 – Understanding the Dashboard Light: Acknowledging Unwillingness 00:20:35 – Safety as the Signal: Body Relaxation and Providing Inner Security 00:23:44 – Reframing Trauma: Was it the Protector You Needed at the Time? 00:25:00 – Releasing Trauma: Techniques, The Healing Code, and Waking the Tiger 00:26:06 – Finishing the Survival Response: Shaking, Crying, Screaming, and Stretching 00:26:38 – Stress as a Multiplier: Impact on Immune System, Heart, and Aging 00:28:10 – Stress Slows Repair: Inflammation, Cardiovascular Risk, and Cellular Aging 00:29:48 – The Integrative Approach: Changing Your Environments to Support Anti-Stress 00:30:07 – Actionable Stress Solutions: Circadian Rhythm, Nature, and Noise Reduction 00:30:44 – Actionable Stress Solutions: Gratitude, Conscious Breath, and Movement 00:31:32 – Energy Drains to Eliminate: Conflict, Clutter, Scrolling, and Late Caffeine 00:32:17 – Connecting to Greater Purpose: The Super Life Patreon Platform 00:32:54 – Morning/Night Questions: Letting Go, Creating, and Contributing 00:33:17 – Final Toolkit: Slow Breathing, Movement, Nature, Sauna, and Sleep 00:34:25 – The Invitation: Digging into all Layers of a Super Life on Patreon   Thank You to Our Sponsors Therasage: Go to www.therasage.com and use code DARIN at checkout for 15% off Bite Toothpaste: Go to trybite.com/DARIN20 or use code DARIN20 for 20% off your first order. Find More from Darin Olien: Instagram: @darinolien Podcast: SuperLife Podcast Website: superlife.com Book: Fatal Conveniences   Key Takeaway "Stress isn't your enemy — it's your compass. Every wave of tension points you back to what's asking for care, attention, and love. When you stop fighting stress and start listening to it, you don't just survive — you evolve."       Bibliography (selected, peer-reviewed) Sources: Gallup Global Emotions (2024); Gallup U.S. polling (2024); APA Stress in America (2023); Natarajan et al., Lancet Digital Health (2020); Orini et al., UK Biobank (2023); Martinez et al. (2022); Leiden University (2025). Cohen S, Tyrrell DA, Smith AP. Psychological stress and susceptibility to the common cold. N Engl J Med.1991;325(9):606–612. New England Journal of Medicine Cohen S, et al. Chronic stress, glucocorticoid receptor resistance, inflammation, and disease risk. Proc Natl Acad Sci USA. 2012;109(16):5995–5999. PNAS Kiecolt-Glaser JK, et al. Slowing of wound healing by psychological stress. Lancet. 1995;346(8984):1194–1196. The Lancet Kiecolt-Glaser JK, et al. Hostile marital interactions, proinflammatory cytokine production, and wound healing.Arch Gen Psychiatry. 2005;62(12):1377–1384. JAMA Network Tawakol A, et al. Relation between resting amygdalar activity and cardiovascular events. Lancet.2017;389(10071):834–845. The Lancet Epel ES, et al. Accelerated telomere shortening in response to life stress. Proc Natl Acad Sci USA.2004;101(49):17312–17315. PNAS McEwen BS, Stellar E. Stress and the individual: mechanisms leading to disease. Arch Intern Med.1993;153(18):2093–2101. PubMed McEwen BS, Wingfield JC. Allostasis and allostatic load. Ann N Y Acad Sci. 1998;840:33–44. PubMed Felitti VJ, et al. Relationship of childhood abuse and household dysfunction to many leading causes of death in adults (ACE Study). Am J Prev Med. 1998;14(4):245–258. AJP Mon Online Edmondson D, et al. PTSD and cardiovascular disease. Ann Behav Med. 2017;51(3):316–327. PMC Afari N, et al. Psychological trauma and functional somatic syndromes: a systematic review and meta-analysis.Psychosom Med. 2014;76(1):2–11. PMC Goyal M, et al. Meditation programs for psychological stress and well-being: a systematic review and meta-analysis. JAMA Intern Med. 2014;174(3):357–368. PMC Qiu Q, et al. Forest therapy: effects on blood pressure and salivary cortisol—a meta-analysis. Int J Environ Res Public Health. 2022;20(1):458. PMC Laukkanen T, et al. Sauna bathing and reduced fatal CVD and all-cause mortality. JAMA Intern Med.2015;175(4):542–548. JAMA Network Zureigat H, et al. Physical activity lowers CVD risk by reducing stress-related neural activity. J Am Coll Cardiol.2024;83(16):1532–1546. PMC Holt-Lunstad J, Smith TB, Layton JB. Social relationships and mortality risk: a meta-analytic review. PLoS Med.2010;7(7):e1000316. PMC Chen Y-R, Hung K-W. EMDR for PTSD: meta-analysis of RCTs. PLoS One. 2014;9(8):e103676. PLOS Hoppen TH, et al. Network/pairwise meta-analysis of PTSD psychotherapies—TF-CBT highest efficacy overall.Psychol Med. 2023;53(14):6360–6374. PubMed van der Kolk BA, et al. Yoga as an adjunctive treatment for PTSD: RCT. J Clin Psychiatry. 2014;75(6):e559–e565. PubMed Kelly U, et al. Trauma-center trauma-sensitive yoga vs CPT in women veterans: RCT. JAMA Netw Open.2023;6(11):e2342214. JAMA Network Bentley TGK, et al. Breathing practices for stress and anxiety reduction: components that matter. Behav Sci (Basel). 2023;13(9):756. 

"Organic produce isn't necessarily not sprayed with pesticides. There's different types of pesticides. They just aren't allowed to use synthetic pesticides. Sometimes they can be even more toxic. Sometimes they have to use larger amounts because they're less effective especially given the cost difference between organic and non-organic, I don't see that it's really warranted for something" - Dr. Matthew Nagra Many people still believe that what they eat, how they live, their experiences, and even who they share their life with has no impact on their physical health. Today's guest is out to dispel that. Dr. Matthew Nagra is a Naturopathic Physician, and in case you're wondering if a Naturopathic Physician is a real doctor, Dr. Matthew Nagra is a health practitioner who treats people holistically. He follows a scientific and evidence-based approach to treating ailments.  Dr. Matthew Nagra practices Integrated Health in Vancouver, BC. He has a BSc in Microbiology from the University of Victoria and completed his ND training at the Boucher Institute. He has been vegan for over 10 years, is certified in plant-based nutrition through the T. Colin Campbell Center for Nutrition Studies. He regularly shares information regarding nutrition and health across his social media pages. Learn how to live healthier as you listen to this episode with Dr. Matthew Nagra.  What we discuss in this episode:  First things first, Dotsie shares 3 things she learned from her book-writing retreat What does a Naturopathic Doctor look for when a patient comes for evaluation compared to what a traditional doctor does? The impact of the food you eat, especially dairy products, when you have asthma Dr. Matthew Nagra talks about what he learned from the nutrition debates in school and the studies on saturated fat, LDL, collagen, etc. Refined sugar vs. fruits – What to do when sugar cravings hit  What does raw veganism mean, and how does it relate to a healthy diet? With book recommendation - Becoming Raw: The Essential Guide to Raw Vegan Diets, and Becoming Vegan, both by Brenda Davis Do you know the massive difference between butter and olive oil? How much sodium does your body need if you are healthy? What you need to know about organic food, non-organic food, and GMO The upside and downside of eating eggs and plant-based sources of choline Watch Dr. Matthew Nagra's debates with carnivores: Vegan vs. Carnivore Debate: Saturated Fat and LDL-Cholesterol and Debating LDL-Cholesterol, Saturated Fat, and CVD with a Carnivore Connect with Dr. Matthew Nagra: Website - https://drmatthewnagra.com/ Instagram - https://www.instagram.com/dr.matthewnagra/ Facebook - https://web.facebook.com/dr.matthewnagra/ Twitter - https://twitter.com/drmatthewnagra   Click the link below to support the FISCAL Act https://switch4good.org/fiscal-act/ Share the website and get your resources here https://kidsandmilk.org/ Send us a voice message and ask a question. We want to hear from you! Switch4Good.org/podcast Dairy-Free Swaps Guide: Easy Anti-Inflammatory Meals, Recipes, and Tips https://switch4good.org/dairy-free-swaps-guide SUPPORT SWITCH4GOOD https://switch4good.org/support-us/ ★☆★ JOIN OUR PRIVATE FACEBOOK GROUP ★☆★  https://www.facebook.com/groups/podcastchat ★☆★ SWITCH4GOOD WEBSITE ★☆★ https://switch4good.org/ ★☆★ ONLINE STORE ★☆★ https://shop.switch4good.org/shop/ ★☆★ FOLLOW US ON INSTAGRAM ★☆★ https://www.instagram.com/Switch4Good/ ★☆★ LIKE US ON FACEBOOK ★☆★ https://www.facebook.com/Switch4Good/ ★☆★ FOLLOW US ON TWITTER ★☆★ https://twitter.com/Switch4GoodOrg ★☆★ AMAZON STORE ★☆★ https://www.amazon.com/shop/switch4good ★☆★ DOWNLOAD THE ABILLION APP ★☆★ https://app.abillion.com/users/switch4good

The bidiretional relationship between cardiac and renal systems means that any dysfunction can cause a cascade of health issues. Learn about team-based care strategies for nurses and other professionals to monitor and manage patients with these conditions from guests Andrew Bzowyckyj, PharmD, BCPS, CDCES, FAPhA, FADCES, and Serina Gbaba, DNP, MBA, FNP-BC.PCNA CKM tools and resources: https://pcna.net/resources/patient-education/patient-information/cardiovascular-kidney-metabolic-syndrome-resources/ IPEC core competencies (Interprofessional Education Collaborative): https://www.ipecollaborative.org/ipec-core-competencies CVD in CKD: Pathophysiological Insights and Therapeutic Options: https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.120.050686Social Determinants of CVD:https://www.ahajournals.org/doi/10.1161/CIRCRESAHA.121.319811See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Mindfulness and Cardiovascular Disease Risk: State of the Evidence, Plausible Mechanisms, and Theoretical FrameworkIn this episode, Dr. Jud Brewer and Dr. Eric Loucks explore the growing body of research on mindfulness and its potential role in reducing cardiovascular disease (CVD) risk. With CVD remaining the leading cause of mortality worldwide, this integrative review examines how mindfulness may impact key risk factors such as smoking, diet, physical activity, obesity, blood pressure, and diabetes regulation. The discussion also unpacks the plausible mechanisms—improved attention control, emotion regulation, and self-awareness—that could explain mindfulness's effects on heart health. Tune in to discover how mindfulness could be a game-changer for preventive cardiology and overall well-being.Full Reference:Loucks, E. B., Schuman-Olivier, Z., Britton, W. B., Fresco, D. M., Desbordes, G., Brewer, J. A., & Fulwiler, C. (2015). Mindfulness and cardiovascular disease risk: State of the evidence, plausible mechanisms, and theoretical framework. Current Cardiology Reports, 17(112). https://doi.org/10.1007/s11886-015-0668-7Let's connect on Instagram

In episode 610, Jamie and James chat with Jennifer Young about yet another Vitamin D Tools for Practice. We look at what happens to mortality, CVD and cancer when Vitamin D supplements are compared to placebo. The results may surprise you – or maybe not if you have listened to previous BS Medicine Podcasts on […]

In this episode, Zach Boyajian returns for a long-awaited Part 2 with futures trader Zach Boyajian. They dive deep into prop firm payouts, SIM farming, overconfidence, and the real cost of copy trading. Zach shares how he went from blowing SIM PRO accounts to balancing personal capital and live prop accounts. He explains why a $20K payout doesn't make you a trader if you lost $15K getting there. The conversation unpacks emotional tilt, overtrading, and the boom-bust cycles that trap most new traders. Zach now trades one high-quality setup a day, focused on risk control and longevity. He breaks down how he uses VWAP, volume profile, and CVD to make sense of the ES and YM chaos. This episode is brutally honest, packed with strategy, and a must-listen for anyone in the prop space.Connect with Zach - https://realdealfutures.com/ Futures Bootcamp Tickets - https://asfx.biz/bootcamp/ Sponsor: Top One FuturesLink: ⁠https://www.asfx.biz/tof⁠Code: ASFX for 50% offSponsor: TradezellaLink: ⁠https://tradezella.com?fpr=asfx⁠Code ASFX for 20% off

The PREVENT score in hypertension, GLP-1 mechanism of action in cardiovascular disease, CAD type and statin benefit, and the problem with hospitalization endpoints in HF trials are the topics John Mandrola, MD, discusses in this week's podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I Is the PREVENT Calculator Best for Determining CVD Risk? Insights From a Post Hoc Analysis of SPRINT Trial https://www.medscape.com/viewarticle/prevent-calculator-best-determining-cvd-risk-insights-post-2025a1000svo PREVENT Calculator https://doi.org/10.1016/j.jacc.2025.07.037 SPRINT Trial https://www.nejm.org/doi/full/10.1056/NEJMoa1511939 II GLP-1 Mechanism of Action in CV Disease Analysis of SELECT Trial 10.1016/S0140-6736(25)01375-3 External Link SELECT trial https://www.nejm.org/doi/full/10.1056/NEJMoa2307563 III Statins and CAD Phenotype on CTA and Outcomes Interactions Between Statin Use, CAD Phenotypes on CTA  https://www.jacc.org/doi/10.1016/j.jcmg.2025.05.018 Statin Use for Primary Prevention of CVD https://jamanetwork.com/journals/jama/fullarticle/2795522 IV HHF Endpoints in Heart Failure Trials The Problem with Hospitalization Endpoints in HF Trials https://onlinelibrary.wiley.com/doi/10.1002/ejhf.70070 You may also like: The Bob Harrington Show with the Stephen and Suzanne Weiss Dean of Weill Cornell Medicine, Robert A. Harrington, MD. https://www.medscape.com/author/bob-harrington Questions or feedback, please contact news@medscape.net

Today we're talking about Simon Hill's personal experience with CVD, what prompted him to have early screening for heart disease and what his results have shown. Which is quite surprising.Simon has early signs of heart disease and now he has a decision to make around whether he embarks on early drug treatment or delays treatment to watch how it evolves. As many of us become more pragmatic about health screening, it's a situation that a lot of us will find ourselves in. Especially with the rise in popularity of full body scans.We also have a discussion around fats, the types of fats in the diet and how one may choose to lower their cholesterol with diet and lifestyle.We go on a virtual trip to the supermarket with Simon and discuss the framework for how to choose fats. The things you need to ask yourself about consuming fats, including the dose and what you're eating it with.Simon Hill, a physiotherapist and nutrition scientist, is dedicated to simplifying health and nutrition information. He began his career interested in the physiology and anatomy related to optimal athletic performance. Then, encouraged by his Dad's heart attack, he turned his attention to nutrition's role in preventing disease and optimising health. Concerned about misleading wellness industry trends, he completed a Master of Science in Human Nutrition at Deakin University.

Dr. Leonard Egede, Dr. Rebekah Walker, and Dr. Obinna Ekwunife from the Department of Medicine at the University of Buffalo, NY, describe their #research paper #published in Volume 17, Issue 8 of Aging-US, entitled “Longitudinal relationship between social and CVD risk factors in older adults with prediabetes: the HRS 2006-2016.” #interview #authorinterview #aging #prediabetes #cardiovascular #health #openaccess #openscience #peerreviewed #journal #publication #publishing #meded DOI - https://doi.org/10.18632/aging.206308 Corresponding author - Leonard E. Egede - legede@buffalo.edu Video interview - https://www.youtube.com/watch?v=1MSTk3GQAGA Video transcript - https://aging-us.net/2025/10/08/behind-the-study-social-and-cardiovascular-risk-factors-in-older-adults-with-prediabetes/ Abstract Background: This study examines how multiple social risk factors influence cardiovascular disease (CVD) risk control over time in older adults with prediabetes using a nationally representative cohort. Methods: Data from the Health and Retirement Study (HRS) included 5,086 U.S. adults aged 50+ with prediabetes. Five social risk domains (economic stability, environment, education, healthcare, and social context) were examined as independent variables, while CVD risk factors included glycemic control (HbA1c), systolic blood pressure (SBP), and cholesterol ratio (total cholesterol/high-density lipoprotein). Mixed-effects models assessed relationships between social risk factors and CVD outcomes, adjusting for age, gender, race, and marital status. Results: The sample had an average age of 68.6 years, with 60.2% female, and 70.97% identifying as non-Hispanic Black. Average HbA1c was 5.7, SBP 129.4, and cholesterol ratio 3.85. Limited education was consistently associated with increased CVD risk—HbA1c (β = 0.03, 95% CI: 0.01–0.06, p < 0.001), SBP (β = 4.34, 95% CI: 2.96–5.71, p < 0.001), and cholesterol ratio (β = 0.08, 95% CI: 0.01–0.16, p < 0.05) —in the fully adjusted model. Medication cost-related non-adherence was significantly associated with higher HbA1c levels (β = 0.03, 95% CI: 0.002–0.06, p < 0.05). Difficulty paying bills and lack of health insurance were both significantly associated with higher cholesterol levels (β = 0.03, 95% CI: 0.002–0.06, p < 0.05) and (β = 0.22, 95% CI: 0.15–0.30, p < 0.001), respectively. Conclusions: Social risk factors, particularly limited education, significantly impact CVD risk in older adults with prediabetes. Sign up for free Altmetric alerts about this article - https://aging.altmetric.com/details/email_updates?id=10.18632%2Faging.206308 Subscribe for free publication alerts from Aging - https://www.aging-us.com/subscribe-to-toc-alerts Keywords - aging, prediabetes, social determinants of health, health equity, cardiovascular health, population health To learn more about the journal, visit https://www.Aging-US.com​​ and connect with us on social media at: Facebook - https://www.facebook.com/AgingUS/ X - https://twitter.com/AgingJrnl Instagram - https://www.instagram.com/agingjrnl/ YouTube - https://www.youtube.com/@AgingJournal LinkedIn - https://www.linkedin.com/company/aging/ Bluesky - https://bsky.app/profile/aging-us.bsky.social Pinterest - https://www.pinterest.com/AgingUS/ Spotify - https://open.spotify.com/show/1X4HQQgegjReaf6Mozn6Mc MEDIA@IMPACTJOURNALS.COM

Tune into this podcast from Dr Clíona Ní Cheallaigh to learn how to provide person-centered care for treatment-experienced people with HIV. Gain strategies to address each individual's specific history and needs while considering the potential impact of comorbidities and other health challenges. Topics covered include:Individualizing Antiretroviral Regimens for Treatment-Experienced People With HIVStrategies to Improve Adherence and Addressing Barriers to Engagement in CarePerson-Centered, Trauma-Informed CareResistance Testing in the Setting of Virologic FailureSelection of ARVs With a Failing RegimenPresenters:Clíona Ní Cheallaigh, MB, MRCP, PhDConsultant PhysicianInclusion Health ServicesSt James's Hospital DublinAssociate ProfessorDepartment of MedicineTrinity College DublinDublin, IrelandLink to full program:https://bit.ly/4oiYxExGet access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Stress isn't just something to “manage” — it's a signal, a teacher, and often, an invitation to look deeper at our health, our choices, and our lives. In this solo episode, Darin reframes stress not as an enemy, but as a dashboard light pointing toward misalignments in our nervous system, environment, relationships, and purpose. Drawing on science, practical tools, and personal insight, Darin reveals how layered stress silently drains our vitality — and how to transform it into an ally for growth, healing, and deeper contentment. Whether it's hidden trauma, toxic environments, unresolved conflict, or the modern distractions constantly pulling at our attention, Darin lays out a roadmap to stop the leaks and reclaim the energy already within you. This episode is a powerful reminder: stress isn't the end of the story — it's the beginning of awareness, safety, and a super life.     What You'll Learn in This Episode [00:00] Introduction to the Super Life podcast [03:27] Why stress might not be your enemy [04:17] Stress as an ally: the signals it gives us about misalignment [04:32] The dashboard light metaphor: how stress reveals hidden issues [05:28] The illusion of “no choice” and the infinite possibilities always available [06:12] Global stress statistics and why most people underestimate their stress load [07:23] Hidden stress revealed through heart rate variability and physiology [08:23] Layered stress: how sleep, exercise, and poor choices compound each other [09:25] Safety vs. calm — why your nervous system craves safety first [10:15] Trauma and the unconscious mind: how old wounds drive our stress response [11:54] Inner narratives and negative self-talk as hidden stress multipliers [12:22] The role of community and your social field in stress and resilience [13:53] Relationships, honesty, and how your circle shapes your energy [14:55] Why boundaries around media and politics are vital for mental clarity [17:42] Finding micro-purpose when life feels overwhelming [18:52] Environmental layers of stress — light, air, and clutter [19:15] The existential layer: stress from living without service or purpose [20:12] Stress as a risk amplifier — how it undermines healing and health [20:55] The deeper truth of safety, connection, and higher power [23:00] Practical tools: breathing, grounding, nature, and conscious choices [24:01] Trauma reframed: not a problem, but a protector at the time [25:25] Lessons from Peter Levine and wild animals: releasing trauma physically [26:04] Questions to ask trauma: “What are you protecting me from?” [26:56] Stress as a multiplier of aging, disease, and poor outcomes [29:20] Why stress isn't a single cause — it's layered and chronic [30:18] Anti-stress strategies: circadian rhythm, nature, and gratitude [31:49] Energy leaks to avoid: clutter, poor food, scrolling, bad boundaries [32:22] What matters most: service, contribution, and alignment [33:28] Final toolkit: breathwork, movement, nature, sleep, and gratitude [34:38] The deeper invitation: step into sovereignty and live your SuperLife     Thank You to Our Sponsors: Manna Vitality: Go to mannavitality.com/  or use code DARIN20 for 20% off your order. Bite Toothpaste: Go to trybite.com/DARIN20 or use code DARIN20 for 20% off your first order.     Find More from Darin Olien: Instagram: @darinolien Podcast: SuperLife Podcast Website: superlife.com Book: Fatal Conveniences Check out my podcast with Dr. Amy Abbington     Key Takeaway “Stress is not the enemy. It's a dashboard light — a teacher showing you where you're out of alignment. When you reframe stress, you reclaim your energy and create space for healing, safety, and the joy of living a super life.”     Bibliography (selected, peer-reviewed) Sources: Gallup Global Emotions (2024); Gallup U.S. polling (2024); APA Stress in America (2023); Natarajan et al., Lancet Digital Health (2020); Orini et al., UK Biobank (2023); Martinez et al. (2022); Leiden University (2025). Cohen S, Tyrrell DA, Smith AP. Psychological stress and susceptibility to the common cold. N Engl J Med.1991;325(9):606–612. New England Journal of Medicine Cohen S, et al. Chronic stress, glucocorticoid receptor resistance, inflammation, and disease risk. Proc Natl Acad Sci USA. 2012;109(16):5995–5999. PNAS Kiecolt-Glaser JK, et al. Slowing of wound healing by psychological stress. Lancet. 1995;346(8984):1194–1196. The Lancet Kiecolt-Glaser JK, et al. Hostile marital interactions, proinflammatory cytokine production, and wound healing.Arch Gen Psychiatry. 2005;62(12):1377–1384. JAMA Network Tawakol A, et al. Relation between resting amygdalar activity and cardiovascular events. Lancet.2017;389(10071):834–845. The Lancet Epel ES, et al. Accelerated telomere shortening in response to life stress. Proc Natl Acad Sci USA.2004;101(49):17312–17315. PNAS McEwen BS, Stellar E. Stress and the individual: mechanisms leading to disease. Arch Intern Med.1993;153(18):2093–2101. PubMed McEwen BS, Wingfield JC. Allostasis and allostatic load. Ann N Y Acad Sci. 1998;840:33–44. PubMed Felitti VJ, et al. Relationship of childhood abuse and household dysfunction to many leading causes of death in adults (ACE Study). Am J Prev Med. 1998;14(4):245–258. AJP Mon Online Edmondson D, et al. PTSD and cardiovascular disease. Ann Behav Med. 2017;51(3):316–327. PMC Afari N, et al. Psychological trauma and functional somatic syndromes: a systematic review and meta-analysis.Psychosom Med. 2014;76(1):2–11. PMC Goyal M, et al. Meditation programs for psychological stress and well-being: a systematic review and meta-analysis. JAMA Intern Med. 2014;174(3):357–368. PMC Qiu Q, et al. Forest therapy: effects on blood pressure and salivary cortisol—a meta-analysis. Int J Environ Res Public Health. 2022;20(1):458. PMC Laukkanen T, et al. Sauna bathing and reduced fatal CVD and all-cause mortality. JAMA Intern Med.2015;175(4):542–548. JAMA Network Zureigat H, et al. Physical activity lowers CVD risk by reducing stress-related neural activity. J Am Coll Cardiol.2024;83(16):1532–1546. PMC Holt-Lunstad J, Smith TB, Layton JB. Social relationships and mortality risk: a meta-analytic review. PLoS Med.2010;7(7):e1000316. PMC Chen Y-R, Hung K-W. EMDR for PTSD: meta-analysis of RCTs. PLoS One. 2014;9(8):e103676. PLOS Hoppen TH, et al. Network/pairwise meta-analysis of PTSD psychotherapies—TF-CBT highest efficacy overall.Psychol Med. 2023;53(14):6360–6374. PubMed van der Kolk BA, et al. Yoga as an adjunctive treatment for PTSD: RCT. J Clin Psychiatry. 2014;75(6):e559–e565. PubMed Kelly U, et al. Trauma-center trauma-sensitive yoga vs CPT in women veterans: RCT. JAMA Netw Open.2023;6(11):e2342214. JAMA Network Bentley TGK, et al. Breathing practices for stress and anxiety reduction: components that matter. Behav Sci (Basel). 2023;13(9):756. 

The Government's 10-year plan for the NHS (‘Fit for the future') has a dedicated section on prevention, including a ‘moonshot' to end the obesity epidemic. But what is the role of GP in the prevention of cardiovascular disease (CVD)?In this episode of the Clinical Update podcast, the MIMS Learning editors explore NICE recommendations for combination therapy to help patients achieve lipid targets for secondary prevention, the promotion of SGLT2 inhibitors to first-line options for both heart failure and type 2 diabetes, and the differences between UK and international guidelines on hypertension. Additionally, given obesity is a huge risk factor for CVD, the editors review how the management of obesity must encompass more than just GLP-1 medications.Educational objectivesAfter listening to this podcast, healthcare professionals should be better able to: Outline the prevention steps proposed in the NHS 10-year planDiscuss additional therapeutic options for achieving lipid targetsReview revised recommendations for heart failure and type 2 diabetesUnderstand the differences between UK and international hypertension targetsYou can access the website version of this podcast, along with a list of key learning points, on MIMS Learning - and make notes for your appraisal. MIMS Learning offers hundreds of hours of CPD for healthcare professionals, along with a handy CPD organiser.Please note: this podcast is presented by medical editors and discusses educational content written or presented by doctors, nurses and other healthcare professionals on the MIMS Learning website and at live events.MIMS LearningSubscribe to MIMS LearningGuidance update: latest NICE guidelines on cardiovascular disease risk assessment and reductionGuidance update: NICE guidelines on hypertensionObesity in adultsPodcast: Dr Toni Hazell on weight loss injections and women's healthPodcast: stress and its effect on the heartMIMSNICE confirms first-line role of SGLT2 inhibitors in final heart failure guidanceMonitoring requirements for hyperlipidaemia treatments Hosted on Acast. See acast.com/privacy for more information.

Sigyn Therapeutics, Inc. has announced plans to initiate a multi-site clinical feasibility study evaluating its breakthrough Sigyn Therapy™ in patients with high-risk cardiovascular disease, the world's leading cause of death, according to the World Health Organization. CEO Jim Joyce told Proactive that Sigyn Therapy is a first-in-class whole-blood adsorption technology designed to be deployed on existing dialysis machines already found in hospitals and clinics worldwide. Unlike conventional approaches, the therapy is engineered to address multiple drivers of cardiovascular disease progression in a single treatment. Specific to CVD, Sigyn Therapy has been shown to reduce circulating inflammatory molecules that accelerate disease progression, while simultaneously targeting cholesterol-transporting lipoproteins that are responsible for heart attacks, strokes, and other major adverse cardiovascular events. Building on encouraging results from pre-clinical in vitro studies, the company is expanding its feasibility study protocol to include the measurement of lipoprotein reduction during therapy. This will allow investigators to quantify the dual-action benefit of Sigyn Therapy in reducing both inflammation and lipid-related risks. The upcoming feasibility study will be a critical step toward the company's long-term goal: advancing to a pivotal efficacy study required for potential regulatory clearance and commercialization. If successful, Sigyn Therapy could represent a transformative advancement in the treatment of cardiovascular disease by integrating seamlessly into existing hospital infrastructure while addressing some of the most urgent unmet needs in cardiac care. Joyce added that the company is in the process of modifying its Investigational Device Exemption (IDE) for submission to the FDA, to formally include Ldl-c and Lp(a) reduction as observational endpoints. #proactiveinvestors #sigyntherapeuticsinc #otcqb #sigy #CardiovascularDisease #Dialysis #SigynTherapeutics #MedicalDevices #BloodPurification #ClinicalTrials #Lipoproteins #StatinAlternative #EndStageRenalDisease #FDAReview

In this episode, we discuss the Scottish Cardiovascular DES designed to reduce adverse cardiovascular events by tackling population-wide risk factors like high blood pressure, raised glucose and cholesterol. Professor James McCormack suggests a greater focus on shared decision making with patients,  arguing that the common 10% risk threshold used to trigger treatment is an arbitrary figure that often fails to clearly define what the risk actually entails. He contends that most guidelines can overlook the individual. With years of experience of teaching how to explain and apply evidence, using humour, he advocates for a foundational shift toward a patient-centred model, where treatment decisions are made with patients, not for them. The conversation explores how to put this philosophy into practice. Risk calculators such as ASSIGN and QRISK should not be used as diagnostic dictators, but as educational tools to start a conversation. He is highly critical of using terms like "pre-diabetes" or "high risk," which can cause patients to vastly overestimate their danger and create unnecessary anxiety. The solution is clear communication: using visual aids and explaining absolute benefits - for instance, a statin might change a 10% risk to 7 or 8% over a decade. By moving away from rigid protocols and chasing fluctuating measurements, clinicians can reduce patient fear, build trust through shared decision-making, and ultimately rediscover a more enjoyable and effective way to practice medicine. National cardiovascular disease (CVD) prevention and risk factors toolkit GP Evidence – fantastic site for GPs interested in shared decision making and using patient decision aids, created by Dr Julian Treadwell Complete BS Medicine podcast list – includes the Contented Clinician podcast ASSIGN v2 Cardiovascular calculator PEER simplified Cardiovascular Decision Aid NICE guidance on shared decision making James McCormack YouTube videos The Surrogate Battle - is lower always better? You can subscribe to the SNUG podcast on the following platforms: SNUG podcast on Apple podcasts      SNUG podcast on Spotify Any feedback or comments are welcome via email: alex.defranco@phs.scot    www.snughealth.org.uk 

Program notes:0:53 Who needs a beta blocker after MI1:53 Those with mild reduction of ejection fraction2:53 Confined to those with 40-50% ejection fraction3:15 Revascularization in NSTEMI4:20 Composite outcome5:20 Closes gap, do FFR6:20 May not be physiologically significant6:40 Is lifelong anticoagulation needed after ablation7:41 Occurred less in those who stopped8:30 RSV, cardiac events and hospitalizations9:30 Lower hospitalization in those who got the vaccine10:30 Acute respiratory illness hospitalization11:30 Less benefit with existing CVD or immunocompromise12:15 Several RSV vaccines13:16 End

Join Dr. Philip Ovadia and Practice Manager Cherish Thompson for a compelling conversation on cardiovascular disease (CVD) and the path to restoring health and quality of life. They'll explore the importance of early diagnostics, working with a cardiothoracic surgeon, and addressing key factors like metabolic health, LDL cholesterol, and lifestyle changes. Gain valuable insights into tackling heart disease and making impactful changes to achieve long-term wellness.Send Dr. Ovadia a Text Message. (If you want a response, you must include your contact information.) Dr. Ovadia cannot respond here. To contact his team, please send an email to team@ifixhearts.com Like what you hear? Head over to IFixHearts.com/book to grab a copy of my book, Stay Off My Operating Table. Ready to go deeper? Talk to someone from my team at IFixHearts.com/talk.Stay Off My Operating Table on X: Dr. Ovadia: @iFixHearts Jack Heald: @JackHeald5 Learn more: Stay Off My Operating Table on Amazon Take Dr. Ovadia's metabolic health quiz: iFixHearts Dr. Ovadia's website: Ovadia Heart Health Jack Heald's website: CultYourBrand.com Theme Song : Rage AgainstWritten & Performed by Logan Gritton & Colin Gailey(c) 2016 Mercury Retro RecordingsAny use of this intellectual property for text and data mining or computational analysis including as training material for artificial intelligence systems is strictly prohibited without express written consent from Dr. Philip Ovadia.

Week 0 CFB with CVD

Stream this podcast to learn from experts Alexis E. Horace, PharmD, BCACP,andNimish Patel, PharmD, PhD, AAHIVP, how specialist pharmacists can overcome key barriers to care and apply best practices for optimization of antiretroviral therapy for HIV. Topics covered include: Leveraging pharmacists' expertise to advance HIV treatmentPharmacist roles in HIV care and management The current ART landscapeRegimen simplificationConsideration of patient preferences, health factors, and comorbidities for ART optimizationART management for treatment-experienced patients, including those with multidrug-resistant HIVPresenters:Alexis E. Horace, PharmD, BCACPProfessor of Pharmacy PracticeUniversity of Louisiana at Monroe College of PharmacyNew Orleans CampusCrescentCare Ambulatory Care Clinical Pharmacist, HIV SpecialtyNew Orleans, LouisianaNimish Patel, PharmD, PhD, AAHIVPProfessor of Clinical PharmacyDivision of Clinical PharmacySkaggs School of Pharmacy & Pharmaceutical SciencesUniversity of California, San DiegoLa Jolla, CaliforniaLink to full program: https://bit.ly/41agtqQGet access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.

   Slam The Gavel welcomes back Amy Palacios to the podcast. Amy was last on the podcast Season 3, Episodes 146, 165 and 179; Season 4, Episodes 134, 145 and 150; Season 5, Episodes 22, 70, 73, 83, 186, 191 and 281. The last time Amy was on we discussed, "Proving The Pattern At The Federal Level."      Amy has two ex husbands being represented by the same attorney, H. Jay White. This attorney also represented Amy at the very beginning of her case years ago. How can an attorney who has represented three people not be in conflict of interest??      Discussing her open Federal Lawsuit  5.25-CV-249-FL, Amy states that most federal lawsuits get dismissed in 30 days. Amy explained that this was the first time she has gone into the state court and actually be heard and turn in evidence, however, at the end of the trial they told her to come back in two months to get a verdict.     Amy read her complaint for Declaratory Judgement to vacate all orders in Cabarrus County, NC. Her opening statement is something everyone can learn from: "Today is my complaint for the record. I am invoking my Federal Protections. The United States Constitution, American Disabilities Act and the Violence Against Women Act. Today is my Declaratory Judgement complaint to vacate all Cabarrus County orders, to void the orders under 18-CVD-3436 and void all Child Support Orders under the 22-CVD and to return to the Mecklenburg County Order 08-CVD-25890 that was done in 2015....." To Reach Amy Palacios:  dismntlingfamilycourtcorruption.comSupportshow(https://www.buymeacoffee.com/maryannpetri)Maryann Petri: dismantlingfamilycourtcorruption.comhttps://www.tiktok.com/@maryannpetriFacebook:  https://www.youtube.com/@slamthegavelpodcasthostmar5536Instagram: https://www.instagram.com/guitarpeace/Pinterest: Slam The Gavel Podcast/@guitarpeaceLinkedIn: https://www.linkedin.com/in/maryann-petri-62a46b1ab/  YouTube:  https://www.youtube.com/@slamthegavelpodcasthostmar5536  Twitter https://x.com/PetriMaryannEzlegalsuit.com   https://ko-fi.com/maryannpetrihttps://www.zazzle.com/store/slam_the_gavel/about*DISCLAIMER* The use of this information is at the viewer/user's own risk. Not financial, medical nor legal advice as the content on this podcast does not constitute legal, financial, medical or any other professional advice. Viewer/user's should consult with the relevant professionals. Reproduction, distribution, performing, publicly displaying and making a derivative of the work is explicitly prohibited without permission from content creator. Podcast is protected by owner. The content creator maintains the exclusive right and any unauthorized copyright infringement is subject to legal prosecution. Support the showSupportshow(https://www.buymeacoffee.com/maryannpetri)http://www.dismantlingfamilycourtcorruption.com/

Arzoo CVD by Jawahrat Jewellery, Nepal's first lab-grown diamond house, crafts certified fine jewellery using advanced CVD technology. Co-founded by Bipana Mitruka and Sahil Agarwal, the brand champions ethical luxury through sustainable, affordable, and bespoke designs—reshaping South Asia's jewellery market with transparency and innovation.

In the UK there are currently about 7.2 million people diagnosed with cardiovascular disease, which amounts to about 10% of the population. Dr Jonathan Slade, GP and Medical Director for NHS England North East and Yorkshire, leads a discussion around the current focus on cardiovascular disease and the very real opportunities for prevention presented within primary care. The panel includes consultant pharmacist Dr Rani Khatib, National Specialty Advisor for CVD Prevention at NHS England. For more information on CVD prevention visit https://www.england.nhs.uk/ourwork/clinical-policy/cvd/prevention-recovery/ For more detail on CVD Prevent visit https://www.england.nhs.uk/ourwork/clinical-policy/cvd/cvdprevent/ A full transcript of this episode is available on our website - https://www.england.nhs.uk/long-read/podcast-cracking-down-on-cardiovascular-disease/

Episode Highlights With JessicaWhy does cardiovascular disease risk rise in menopause to match the rate of men?What happens to hormones and the heart when a woman goes through menopause?45% of women have some marker of cardiovascular diseaseHow the loss of estrogen in menopause is the tipping point1 in 3 women will die of cardiovascular disease which is more than all cancers combinedWhat to monitor and look out for starting in our 20s50% of people in the US have high blood pressure and this is a marker of metabolic diseaseHow insulin comes into play and why this marker is so importantWhat metabolic markers to start tracking to know your riskHow visceral fat comes into play and why this is importantWhat causes visceral fat to accumulate in the bodyHer take on microdosing GLP-1 medication and if you lose lean muscleResources MentionedThe Loving Diet - websiteJessica's Instagram

Experts discuss effective communication strategies to empower patients of their options, set realistic expectations, and guide them towards informed decisions. Claim CE and MOC Credits at https://bit.ly/VTEComm

PPH is terrible. PPH must be assessed quickly via the “4Ts” and acted upon in a timely manner. And listen to this: new data from the Journal of Maternal-Fetal & Neonatal Medicine (June 24, 2025 ahead of print) finds an association with PPH and adverse outcomes years later: the odds of cardiovascular disease (CVD) and thromboembolism disease are increased in patients with postpartum hemorrhage (PPH), to a magnitude of 1.76 fold. That's why these authors recommended "proactive postpartum care". That's what we're gonna talk about in this episode. Control of PPH includes bladder drainage, uterine massage, medications as appropriate, and mechanical methods of bleeding control. So… Vacuum uterine contraction works, and a balloon works. Even a simply 24 Fr foley has efficacy data in this setting as a uterine tamponade tool. But, in an attempt to have a LOW-COST, HIGHLY EFFECTIVE, and easy to use alternative to the Jada and Bakri- could we just use an intrauterine foley catheter and connect that to vacuum suction? JADA is effective but it limited based on uterine (EGA) size, or in cases of uterine anomaly. But most importantly…JADA and Bakri are expensive! Well, we now have data that this approach, using a low-cost, easy to use alternative, may be a consideration. It is FOCUS. This idea comes from one of our podcast family members, Dr. Frank Jackson- an MFM fellow- who has published his experience with this and already has a new publication on this technique (FOCUS), which was released as we were recording this very episode! Listen in for details.

In this debut episode of JACC This Week with Editor-in-Chief Dr. Harlan Krumholz, we explore groundbreaking studies and timely insights from the July 1st issue. Highlights include the impact of wildfire smoke on heart failure risk, new hemodynamic data on mechanical circulatory support in cardiogenic shock, and sobering cardiovascular mortality trends over the past 25 years. Plus, updates on aspirin use, cognitive impairment in CVD, ACC/AHA performance measures, and a leadership reflection from ACC President Dr. Christopher Kramer.

In this episode, CardioNerds Dr. Gurleen Kaur, Dr. Richard Ferraro, and Dr. Jake Roberts are joined by Cardio-Rheumatology expert, Dr. Monica Mukherjee, to discuss the role of utilizing multimodal imaging for cardiovascular disease risk stratification, monitoring, and management in patients with chronic systemic inflammation. The team delves into the contexts for utilizing advanced imaging to assess systemic inflammation with cardiac involvement, as well as the role of imaging in monitoring various specific cardiovascular complications that may develop due to inflammatory diseases. Audio editing by CardioNerds academy intern, Christiana Dangas. CardioNerds Prevention PageCardioNerds Episode PageCardioNerds AcademyCardionerds Healy Honor Roll CardioNerds Journal ClubSubscribe to The Heartbeat Newsletter!Check out CardioNerds SWAG!Become a CardioNerds Patron! Pearls - Cardiovascular Multimodality Imaging & Systemic Inflammation Systemic inflammatory diseases are associated with an elevated CVD risk that has significant implications for early detection, risk stratification, and implementation of therapeutic strategies to address these risks and disease-specific complications. As an example, patients with SLE have a 48-fold increased risk for developing ASCVD compared to the general population. They may also develop disease-specific complications, such as pericarditis, that require focused imaging approaches to detect. In addition to increasing the risk for CAD, systemic inflammatory diseases can also result in cardiac complications, including myocardial, pericardial, and valvular involvement. Assessment of these complications requires the use of different imaging techniques, with the modality and serial studies selected based on the suspected disease process involved. In most contexts, echocardiography remains the starting point for evaluating cardiac involvement in systemic inflammatory diseases and can inform the next steps in terms of diagnostic study selection for the assessment of specific cardiac processes. For example, if echocardiography is completed in an SLE patient and demonstrates potential myocardial or pericardial inflammation, the next steps in evaluation may include completing a cardiac MRI for better characterization. While no current guidelines or standards of care directly guide our selection of advanced imaging studies for screening and management of CVD in patients with systemic inflammatory diseases, our understanding of cardiac involvement in these patients continues to improve and will likely lead to future guideline development. Due to the vast heterogeneity of cardiac involvement both across and within different systemic inflammatory diseases, a personalized approach to caring for each individual patient remains central to CVD evaluation and management in these patients. For example, patients with systemic sclerosis and symptoms of shortness of breath may experience these symptoms due to a range of causes. Echocardiography can be a central guiding tool in assessing these patients for potential concerns related to pulmonary hypertension or diastolic dysfunction. Based on the initial echocardiogram, the next steps in evaluation may involve further ischemic evaluation or right heart catheterization, depending on the pathology of concern. Show notes - Cardiovascular Multimodality Imaging & Systemic Inflammation Episode notes drafted by Dr. Jake Roberts. What are the contexts in which we should consider pursuing multimodal cardiac imaging, and are there certain inflammatory disorders associated with systemic inflammation and higher associated CVD risk for which advanced imaging can help guide early intervention? Systemic inflammatory diseases are associated with elevated CVD risk, which has significant implications for early detection, risk stratification, prognostication, and implementation of therapeutic strategies to address CVD risk and complicat...

Graphite anode materials may become even more difficult to obtain from China as preliminary CVD rates are released. Listen to Two Minutes in Trade for more. 

During this episode a panel of experts discuss the patient journey through the interpretation and application of safety and efficacy data to establish and maintain protocols designed to address optimal VTE treatment pathways. Claim CE and MOC Credit at bit.ly/VTEPJ6 

How Can I Lower My Triglycerides? “Going to the doctor for your fasting lipid panel results can be an exercise in confusion. You will get numbers for your total cholesterol, LDL cholesterol (“unhealthy” cholesterol), HDL cholesterol (“healthy” cholesterol), and triglycerides. Although the major emphasis in treating abnormal lipid panel results focuses on getting LDL cholesterol below a certain level, your doctor might also make recommendations about your HDL and triglycerides.” Listen to today's episode for details, written by Thomas Campbell, MD at NutritionStudies.org  #vegan #plantbased #plantbasedbriefing #lipid #triglycerides #cholesterol #cvd #cardiovasculardisease #lipidpanel   ======================== Original post: https://nutritionstudies.org/lower-triglycerides/  ========================== Related Episodes: 861: Eat Quinoa and Lower Triglycerides? https://plantbasedbriefing.libsyn.com/861-eat-quinoa-and-lower-triglycerides-by-dr-michael-greger-at-nutritionfactsorg  Related Episodes: use search feature at https://www.plantbasedbriefing.com/episodes-search     Search for cholesterol, heart disease ========================= The T. Colin Campbell Center for Nutrition Studies was established to extend the impact of Dr. Campbell's life changing research findings. For decades, T. Colin Campbell, PhD, has been at the forefront of nutrition education and research. He is the coauthor of the bestselling book, The China Study, and his legacy, the China Project, is one of the most comprehensive studies of health and nutrition ever conducted. Their mission is to promote optimal nutrition through science-based education, advocacy, and research. By empowering individuals and health professionals, we aim to improve personal, public, and environmental health. ====================== FOLLOW THE SHOW ON: YouTube: https://www.youtube.com/@plantbasedbriefing     Spotify: https://open.spotify.com/show/2GONW0q2EDJMzqhuwuxdCF?si=2a20c247461d4ad7 Apple Podcasts: https://podcasts.apple.com/us/podcast/plant-based-briefing/id1562925866 Your podcast app of choice: https://pod.link/1562925866 Facebook: https://www.facebook.com/PlantBasedBriefing   LinkedIn: https://www.linkedin.com/company/plant-based-briefing/   Instagram: https://www.instagram.com/plantbasedbriefing/     

In 2016 the American Heart Association called for Cardiorespiratory Fitness (CRF), generally measured using VO2max, to be included as a vital sign. They said:“The underlying premise of this statement is that the addition of CRF for risk classification presents health professionals with unique opportunities to improve patient management and to encourage lifestyle-based strategies designed to reduce cardiovascular risk.”In this episode we discuss the arguments made and evidence cited in that statement, as well the update published in 2024.If you're the type to want follow up citations/further readings, here are a few that we found interesting (but you can find many more cited in the two statements linked above):People over 60 can still improve their VO2 by just as much as young people, relative to their baseline.Here's where you'll find the normative values from the Fitness Registry and the Importance of Exercise National Database (FRIEND) that we discussed.And before you ask, we also briefly address the classic "strength vs cardio" debate. Here are some studies we used to support it:Association of Resistance Exercise with Cardiovascular Disease Morbidity and Mortality (yes, we understand that CVD is probably not the right place to look for strength training benefits)Optimum dosing of resistance training for health and longevity

This week's topics include aging and diet, blood based biomarkers for dementia, ten and thirty year risk for cardiovascular disease, and global effect of cardiovascular risk factors.Program notes:1:00 Five factors and cardiovascular disease2:00 Additional life years free of CVD3:00 Irrespective of where you live3:27 Optimal dietary patterns for healthy aging4:28 Higher intake of fruits, vegetables5:28 Little bit better one or another6:28 Can actually change this6:40 Ten and thirty year CVD risk7:40 Risk at ten and thirty years disparate8:40 Increased cholesterol or blood pressure9:20 Blood based biomarkers10:20 Dementia free adults11:20 Risk low with none of the factors12:27 End

In this episode, a panel of experts discuss existing and emerging VTE (venous thromboembolism) treatment options for the complex patient, such as a patient who has been diagnosed with cancer, end stage renal disease (ESRD), chronic kidney disease (CKD), or is obese.  Claim CE and MOC Credit at https://bit.ly/VTEHBCPX

View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter's Weekly Newsletter In this "Ask Me Anything" (AMA) episode, Peter explores the complex world of supplements by introducing a practical framework for evaluating their effectiveness and relevance to individual health needs. Rather than providing a simple list of recommendations, Peter aims to equip listeners with the tools to critically assess supplements on their own. He then applies this framework to discuss research on several popular supplements, including creatine, fish oil, vitamin D, B vitamins, and ashwagandha. Additionally, he covers key factors in assessing supplement quality, helping listeners develop a deeper understanding of how to make informed decisions based on their personal health goals. If you're not a subscriber and are listening on a podcast player, you'll only be able to hear a preview of the AMA. If you're a subscriber, you can now listen to this full episode on your private RSS feed or our website at the AMA #69 show notes page. If you are not a subscriber, you can learn more about the subscriber benefits here. We discuss: Overview of episode topics [1:45]; How Peter evaluates patients' supplement regimens, and common misconceptions about supplements vs. pharmaceuticals [3:00]; A framework for evaluating supplements [6:15]; Evaluating creatine: purpose of supplementation, dosing, and mechanism of action [10:00]; Creatine: proven benefits for muscle performance, potential cognitive benefits, and why women may benefit more [15:15]; Creatine: risk vs. reward, kidney concerns, and choosing the right supplement [18:45]; Evaluating fish oil: its primary purpose as a supplement and how to track levels [20:45]; Fish oil: how omega-3s impact inflammation, heart health, and brain function, and the strengths and limitations of current research [26:30]; Fish oil: the risks of supplementation, guidance on selecting high-quality products, and how to determine whether supplementation is appropriate [37:30]; Evaluating vitamin D: understanding deficiency and optimal levels [45:15]; Vitamin D: role in bone health, immune function, potential longevity impact, and biomarker limitations [51:15]; Vitamin D: efficacy, safety, and balancing risk vs. reward [58:15]; Evaluating B vitamins: function, consequences of deficiency, and key biomarkers to assess whether supplementation is necessary [1:02:15]; B vitamins: risks for CVD and dementia associated with deficiency, and limited evidence for general population supplementation [1:07:15]; Evaluating ashwagandha: background, uses, and mechanism of action [1:15:30]; Ashwagandha: current evidence for its effects on sleep, stress, and anxiety [1:19:15]; Ashwagandha: evaluating supplement quality, safety profile, and the risk-reward balance [1:22:15]; The importance of using a structured evaluation framework to assess any supplement [1:26:30]; and More. Connect With Peter on Twitter, Instagram, Facebook and YouTube

Dana will be 54 on Mar 1st, 2025 and is 5'2 at 110 lbs.  She started IF on SEPT 5, 2023, after learning about it on a podcast focusing on Alzheimer's / dementia prevention/mitigation.  She was listening to that podcast b/c she lost both parents-in-law to this horrible disease. Within 1 week of starting IF, she remembers saying out loud to her husband, “I feel fantastic. I don't think I'll ever want to stop doing this.”  She never had a weight problem but suffered from a horrible sugar addiction and was raised on UPFs and LOVED sugar, especially chocolate, since she was 3 years old. Old.  She used sugar/chocolate and UPFs her whole life as a way to soothe, celebrate, comfort, connect, etc. and has struggled with emotional eating FOREVER.  Since she never really struggled much with her weight and didn't drink alcohol or smoke cigs, she always justified the emotional eating with, “No big deal - it's my one vice.”  However, her father died at 51 of a massive heart attack, as did his father and his brother, so CVD runs in her family.  On Easter of 2016, she had just binged her son's Easter candy. She was watching Dr Phil when she saw an episode about “SKINNY FAT” people - she had a significant epiphany and started a program called “28-day shred”, which was paleo eating and lost 10 lbs (going from 128-118), then took 1 day off and did another round losing six more lbs.  She only ate sugar in those 60 days once but was miserable and felt weak -she couldn't keep eating that way.  So she stopped and slowly started consuming too much sugar and UPFs again.  IF has helped her sugar cravings as well as a MILLION other NSV's.  Our Patreon Supporters Community -Join us!Please consider joining the Fasting Highway Patreon community. The feedback has been great for all who have joined. It has become an excellent add-on to our Patreon members' IF lifestyle, who enjoy a lot of bonus content to support them in living an IF life for as little as 0.16 cents a day For less than a cup of coffee a month, you can join and support your own health goals and meet like-minded people and get a lot of supportGraeme hosts Zoom meetings four times a month in the Northern and Southern hemispheres for members to come and get support for their IF lifestyle, which has proven very popular with our Patreon members.You will not find anywhere that provides that kind of support and accountability for just 0.16 cents a day. There are over 100 exclusive pieces of audio content for Patreon members to help you navigate your IF journey and get more accountability and support. Please go to www.patreon.com/thefastinghighway to see the benefits you get back and how to join. I strongly encourage you to do so for the price of a cup of coffee a month. Its a sound investment into your health.Graeme's best-selling book, The Fasting Highway, about his journey and how he did it, is available in paperback and Kindle at your local Amazon store. It is also available on audio at Applebooks, Kobo, Spotify, and many other audiobook platforms. Graeme can also be booked for one-on-one mentoring and coaching by going to www.thefastinghighway.com, clicking on get help, getting coaching, and booking a time. All times you see are in your local time zone.Disclaimer: Nothing in this podcast should be taken as medical advice. The opinions expressed herein are those of the host and guest only.

This week's topics include AI for mental illness, maternal death worldwide, CVD, education and income in the US, and sleep spindles and regain of consciousness.

For years, we've been conditioned to fear cholesterol—especially LDL. But the real problem isn't just LDL itself. The real issue? Inflammation. LDL becomes dangerous when it gets oxidized, triggering arterial damage and plaque buildup. This is why focusing only on total cholesterol or LDL isn't enough. If you really want to understand your true cardiovascular risk, here's what actually matters:

Oatmeal has long been considered a heart-healthy breakfast, but is it really as good for us as we think? In this episode, Jonathan and Sarah break down the great oat debate. First, they explore the different types of oats - instant, rolled, and steel-cut and how processing impacts their nutritional value. Then, they put oats to the test using continuous glucose monitors (CGMs), comparing instant to steel-cut, with and without toppings, to demonstrate how blood sugar works. Sarah also discusses wider debates around oats: Are pesticides a concern? Is oat milk as healthy as it claims? Finally, she shares the ultimate guide to choosing the healthiest oats - and for those who prefer alternatives, she's got delicious, nutrient-packed swaps to try.

Something I've become a lot more knowledgeable about after my training as a GP, is cholesterol. It's probably the most important measurement every primary care doctor should know about, along with measures of metabolic health like weight, insulin resistance and blood pressure, but perhaps the least well understood.On today's episode we do a deep dive into all things cholesterol and cardiovascular disease with Professor Kausik Ray, Professor of Public Health and Honorary Cardiologist at Imperial College London and President of the European Atherosclerosis Society, and perhaps the most knowledgeable person I could talk to on this subject who has both research and clinical expertise in this area. We define exactly what we're referring to when we say cardiovascular disease (CVD) and atherosclerosis. What that entails and why it's important, being the leading cause of death globally. We discuss the importance of cholesterol in the body. Without cholesterol there is no life. Cholesterol is the precursor to our hormones, it forms the structural components of our cells, and most of our cells are able to create the cholesterol we require hence why there is no nutritional need to consume cholesterol.And, hopefully at the end of this episode you'll learn more about why the trifecta of high cholesterol, inflammation and damage to the arteries leads to disease, what blood measurements we should all have to calculate our risk, including apolipoprotein-B containing lipoproteins, Non-HDL and Lp(a), as well as the strategies to reduce risk with drugs and lifestyle.I've done other episodes on specific foods and dietary patterns to reduce cholesterol, but this I think is a necessary episode to give the backdrop to why this is important for everyone to know their numbers.