Podcasts about cvd

Cardiovascular disease (CVD) is the leading global cause of death, with an estimated 18 million deaths each year (over 30% of all global deaths). In 2022, around 175,000 people in the UK died from CVD, accounting for about 27% of all deaths — the second most common cause of death after dementia and Alzheimer's disease. In this podcast, Dr Thomas Round talks to Dr Nicholas Jones, a salaried GP in Oxford with a special interest in cardiology, about primary risk assessment and lipid management in cardiovascular disease.  EKU Programme module on Cardiovascular disease: risk assessment, reduction & lipid modification. British Journal of General Practice article on Cardiovascular disease — risk assessment and reduction: NICE 2023 update for GPs.

Graphite anode materials may become even more difficult to obtain from China as preliminary CVD rates are released. Listen to Two Minutes in Trade for more. 

During this episode a panel of experts discuss the patient journey through the interpretation and application of safety and efficacy data to establish and maintain protocols designed to address optimal VTE treatment pathways. Claim CE and MOC Credit at bit.ly/VTEPJ6 

How Can I Lower My Triglycerides? “Going to the doctor for your fasting lipid panel results can be an exercise in confusion. You will get numbers for your total cholesterol, LDL cholesterol (“unhealthy” cholesterol), HDL cholesterol (“healthy” cholesterol), and triglycerides. Although the major emphasis in treating abnormal lipid panel results focuses on getting LDL cholesterol below a certain level, your doctor might also make recommendations about your HDL and triglycerides.” Listen to today's episode for details, written by Thomas Campbell, MD at NutritionStudies.org  #vegan #plantbased #plantbasedbriefing #lipid #triglycerides #cholesterol #cvd #cardiovasculardisease #lipidpanel   ======================== Original post: https://nutritionstudies.org/lower-triglycerides/  ========================== Related Episodes: 861: Eat Quinoa and Lower Triglycerides? https://plantbasedbriefing.libsyn.com/861-eat-quinoa-and-lower-triglycerides-by-dr-michael-greger-at-nutritionfactsorg  Related Episodes: use search feature at https://www.plantbasedbriefing.com/episodes-search     Search for cholesterol, heart disease ========================= The T. Colin Campbell Center for Nutrition Studies was established to extend the impact of Dr. Campbell's life changing research findings. For decades, T. Colin Campbell, PhD, has been at the forefront of nutrition education and research. He is the coauthor of the bestselling book, The China Study, and his legacy, the China Project, is one of the most comprehensive studies of health and nutrition ever conducted. Their mission is to promote optimal nutrition through science-based education, advocacy, and research. By empowering individuals and health professionals, we aim to improve personal, public, and environmental health. ====================== FOLLOW THE SHOW ON: YouTube: https://www.youtube.com/@plantbasedbriefing     Spotify: https://open.spotify.com/show/2GONW0q2EDJMzqhuwuxdCF?si=2a20c247461d4ad7 Apple Podcasts: https://podcasts.apple.com/us/podcast/plant-based-briefing/id1562925866 Your podcast app of choice: https://pod.link/1562925866 Facebook: https://www.facebook.com/PlantBasedBriefing   LinkedIn: https://www.linkedin.com/company/plant-based-briefing/   Instagram: https://www.instagram.com/plantbasedbriefing/     

In 2016 the American Heart Association called for Cardiorespiratory Fitness (CRF), generally measured using VO2max, to be included as a vital sign. They said:“The underlying premise of this statement is that the addition of CRF for risk classification presents health professionals with unique opportunities to improve patient management and to encourage lifestyle-based strategies designed to reduce cardiovascular risk.”In this episode we discuss the arguments made and evidence cited in that statement, as well the update published in 2024.If you're the type to want follow up citations/further readings, here are a few that we found interesting (but you can find many more cited in the two statements linked above):People over 60 can still improve their VO2 by just as much as young people, relative to their baseline.Here's where you'll find the normative values from the Fitness Registry and the Importance of Exercise National Database (FRIEND) that we discussed.And before you ask, we also briefly address the classic "strength vs cardio" debate. Here are some studies we used to support it:Association of Resistance Exercise with Cardiovascular Disease Morbidity and Mortality (yes, we understand that CVD is probably not the right place to look for strength training benefits)Optimum dosing of resistance training for health and longevity

This week's topics include aging and diet, blood based biomarkers for dementia, ten and thirty year risk for cardiovascular disease, and global effect of cardiovascular risk factors.Program notes:1:00 Five factors and cardiovascular disease2:00 Additional life years free of CVD3:00 Irrespective of where you live3:27 Optimal dietary patterns for healthy aging4:28 Higher intake of fruits, vegetables5:28 Little bit better one or another6:28 Can actually change this6:40 Ten and thirty year CVD risk7:40 Risk at ten and thirty years disparate8:40 Increased cholesterol or blood pressure9:20 Blood based biomarkers10:20 Dementia free adults11:20 Risk low with none of the factors12:27 End

This episode we dive into a brand new paper published by our very own Lewis Cowan titled: The effect of endurance (low intensity) training on managing the risk and progression of CVD in middle ages adults: a systematic review. Join as we dive into the different topics in Lewis' paper, discussing the effect of low intensity training (LIT) vs high intensity training (HIT) on CVD, Lewis' highlights through this journey, the challenges that come with publishing to research journals and what the future has in store.

In this episode, a panel of experts discuss existing and emerging VTE (venous thromboembolism) treatment options for the complex patient, such as a patient who has been diagnosed with cancer, end stage renal disease (ESRD), chronic kidney disease (CKD), or is obese.  Claim CE and MOC Credit at https://bit.ly/VTEHBCPX

Difficult-to-cut materials are defined as engineering materials with significantly lower machinability than typical. These materials are often referred to in shoptalk as ‘hard-to-machine,' ‘tough-to-cut,' or even ‘nasty.' It is important to note that high hardness is not the only characteristic that makes these materials challenging to machine; several other factors contribute to their machining difficulties. Every industrial branch, in one way or another, must deal with such materials. However, the leading consumer of these materials is the aerospace industry. It is in this sector—whether in the production of turbine engines, landing gear components, or primary airframe elements—that difficult-to-cut materials have found their most significant application. In the aerospace industry, the key characteristics of required materials are strength-to-weight ratio, robustness, fatigue life, and resistance to corrosion and hot temperatures. It turns out that materials meeting these characteristics are difficult to machine, posing a serious challenge for production. When speaking about such materials, the following information should be considered: l High-alloy high-strength steel, l Titanium alloys, l Hot temperature superalloys, l Composites. High-strength steels are used in elements subjected to extreme mechanical load, such as landing gear. They are also the primary material for various fasteners. Titanium alloys, with their excellent strength-to-density ratio, high corrosion-proof, and creep resistance, have become the preferred material for producing the main parts of a jet engine's cold section. These alloys also provide a suitable alternative to steel and stainless steel for weight savings. Hot-temperature superalloys (HTSA), which can maintain their strength in high-temperature environments, are common in the components of a jet engine's hot section. Composites offer impressive specific strength, helping to decrease an aircraft's weight and opening new prospects for aerodynamic fairing. In military aviation, composites contribute to improved aircraft's stealth characteristics. However, machining these materials presents numerous challenges for several reasons. The main challenges are as follows: l High material strength results in significant cutting forces that increase the mechanical load on the cutting tool. l Intensive heat generation and low thermal conductivity of the material (for example, when machining titanium alloys) cause poor heat transfer. This leads to a growing thermal load on the tool and increases the risk of build-up on a cutting edge. l Work hardening of materials (specifically HTSA) increases the strength and hardness of the workpiece surface during cutting, making machining difficult. l The high abrasion factor (when machining composites) intensifies the galling of the tool's active area. Additionally, other specific material features affect machinability. For example, the ‘springiness' of titanium alloys contributes to vibration, worsening machining accuracy and surface finish. The inner structure of composites is associated with material delamination during machining. All the mentioned aspects accelerate tool wear and diminish tool life. The trends in the aerospace industry distinctly point to the increased usage of difficult-to-cut materials. This is manifested by introducing new alloys with higher strength and heat-resistance characteristics, the broad application of composites, and the utilisation of hybrid-structure (metal-composite) materials. To meet these challenges, the metalworking industry introduces new cutting strategies based on the impressive capabilities of modern CNC machines and CAM systems. However, the cutting tool is the final link in the entire machining chain, which directly contacts the material and removes its layer during operation. This link is the most ‘conservative' part of the chain, and its development is slow, often hindering the full utilisation of advanced machines' capabilities. To overcome the existing difficulties, it is necessary to reduce machining data, which leads to low productivity and increased machining costs. Understandably, every step forward, even a small one, in the tool field can significantly improve machining ‘nasty' materials. Therefore, the metalworking industry welcomes the latest advances in cutting tools, hoping they will radically change the situation. What are the main requirements for tools intended for efficient machining of tough-to-cut aerospace materials? In brief, they need to be hard, durable, and precise to enable productive machining while ensuring predictable and stable prolonged tool life and the required accuracy level. However, meeting these understandable and reasonable demands requires significant efforts, and even small progress in this direction faces challenges. Every new advance involves serious R&D work and extensive testing. Hence, tool development focuses on the following areas: Cutting material grades. Tool design. A tool's digital component. The emphasis in cutting materials is on improving hardness, wear resistance, and high-temperature strength. This is achieved by introducing new coatings, particularly those based on nanotechnology, and expanding the use of extra-hard cutting materials like cubic boron nitride (CBN) and ceramics. In tool design, enhancements optimise macro and micro-geometries, such as the cutting edge design and cutting edge preparation, to improve cutting capabilities. Computer modelling, combined with computational dynamics and the impressive possibilities of additive manufacturing (AM), provides new opportunities for shaping flutes, chip gullets, and internal coolant channels. This contributes to better chip evacuation and coolant supply, improving tool performance. A key area is increasing the vibration resistance of the tool through advanced cutting geometry, enhancing the rigidity of the tool structure, and using vibration-damping toolholders. The tool's digital component includes the digital twin and various software products, which allow for virtual assembly, machining simulation, cutting data selection, tool life estimation, and necessary calculations such as machining power and cutting forces. ISCAR expects that this component will be compatible with data exchange standards to meet the requirements of Smart manufacturing. The noted trends are evident in the new developments from ISCAR, one of the leaders in tool manufacturing, presented within the framework of the latest LOGIQUICK campaign. The company has introduced two new carbide grades with PVD coating: IC1017, which ISCAR created for turning Ni-based HTSA, and IC716, which is intended for high-performance indexable milling titanium alloys. The range of chatter-dampening solid carbide endmills has been expanded with contemporary designs made from the bronze-coloured IC608 carbide grade, which is the first choice for the ISO S group of applications (cutting superalloys and titanium). Another carbide grade, IC5600, has been developed by ISCAR's prolific R&D Materials Sciences engineers for milling steel (ISO P group). The combination of the grade's submicron substrate, CVD coating, and post-coating treatment aims to enhance resistance to abrasive wear and thermal loading, increasing cutting speed, particularly when machining high-strength steel. CERAMILL, a new family of endmills with indexable single-sided round inserts (Fig. 1), is interesting from two points of view. First, the family utilises an ingenious mechanism for high-rigidity insert clamping. This mechanism allows for an increased number of teeth compared to a typical design of similar tools in the same diameter. Additionally, it enables simple indexing and insert replacement without removing the endmill from the toolholder. Second, the inserts are produced from ceramic grades specially engineered for machining HTSA. ISCAR has expanded its range of anti-vibration products based on the innovative built-in damping mechanism, which features a heavy mass supported by a rubber spring element containing oil for enhanced dampening. The turning line now includes vibration-absorbing boring bars for machining depths of 12 and 14 times the shank diameter (Fig. 2). Additionally, the milling line has incorporated anti-vibration shanks with MULTI-MASTER adaptation. The QUICK-X-FLUTE is a family of extended flute shell mills developed to achieve high metal removal rates (MRR) in rough milling of challenging materials such as HTSA and titanium (ISO S), austenitic and duplex stainless steel (ISO M), and steel (ISO P). These ‘porcupines' utilise cost-effective, double-sided square inserts with 8 indexable cutting edges. A key aspect of the mill design is the optimised flute geometry (Fig. 3), which balances mill rigidity and the necessity for adequate chip flow when cutting at high MRR. The QUICK-X-FLUTE mills also feature an inner coolant supply option. Using high-pressure pinpointed coolant with replaceable nozzles and face frontal outlets ensures a direct supply of coolant to the cutting zone. This enhances the cooling and lubrication action, contributing to optimal chip control. Effective coolant supply has become a primary emphasis in contemporary tool designs. In the PICCO line of miniature turning tools, ISCAR has introduced new inserts with internal coolant channels (Fig. 4). In hole making; the company has unveiled new 3-flute solid carbide drills for machining flat-bottom holes featuring three coolant outlets. The latest additions to tool holding include holders with coolant channels along the shank bore. Additionally, in ISCAR's classical HELIMILL indexable milling family, the company's R&D engineers have upgraded the design to maximise flow rate with minimal pressure drop using computerised fluid dynamic (CFD) software. Improvements have also been made to NEOITA, an integral part of the company's digital tool component. NEOITA, an expert system that recommends optimal tooling solutions and forecasts tool life for a specific application, now includes new features. One of these is the AI-powered information search, specifically designed to retrieve detailed data on workpiece materials, including their metallurgical composition and typical uses. Enhanced performance in machining difficult-to-cut aerospace materials is a complex challenge. Tool manufacturers continually strive to provide more advanced and productive solutions to address this. While no radical breakthroughs have been observed, recent developments indicate steady evolutionary progress in this area.

View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter's Weekly Newsletter In this "Ask Me Anything" (AMA) episode, Peter explores the complex world of supplements by introducing a practical framework for evaluating their effectiveness and relevance to individual health needs. Rather than providing a simple list of recommendations, Peter aims to equip listeners with the tools to critically assess supplements on their own. He then applies this framework to discuss research on several popular supplements, including creatine, fish oil, vitamin D, B vitamins, and ashwagandha. Additionally, he covers key factors in assessing supplement quality, helping listeners develop a deeper understanding of how to make informed decisions based on their personal health goals. If you're not a subscriber and are listening on a podcast player, you'll only be able to hear a preview of the AMA. If you're a subscriber, you can now listen to this full episode on your private RSS feed or our website at the AMA #69 show notes page. If you are not a subscriber, you can learn more about the subscriber benefits here. We discuss: Overview of episode topics [1:45]; How Peter evaluates patients' supplement regimens, and common misconceptions about supplements vs. pharmaceuticals [3:00]; A framework for evaluating supplements [6:15]; Evaluating creatine: purpose of supplementation, dosing, and mechanism of action [10:00]; Creatine: proven benefits for muscle performance, potential cognitive benefits, and why women may benefit more [15:15]; Creatine: risk vs. reward, kidney concerns, and choosing the right supplement [18:45]; Evaluating fish oil: its primary purpose as a supplement and how to track levels [20:45]; Fish oil: how omega-3s impact inflammation, heart health, and brain function, and the strengths and limitations of current research [26:30]; Fish oil: the risks of supplementation, guidance on selecting high-quality products, and how to determine whether supplementation is appropriate [37:30]; Evaluating vitamin D: understanding deficiency and optimal levels [45:15]; Vitamin D: role in bone health, immune function, potential longevity impact, and biomarker limitations [51:15]; Vitamin D: efficacy, safety, and balancing risk vs. reward [58:15]; Evaluating B vitamins: function, consequences of deficiency, and key biomarkers to assess whether supplementation is necessary [1:02:15]; B vitamins: risks for CVD and dementia associated with deficiency, and limited evidence for general population supplementation [1:07:15]; Evaluating ashwagandha: background, uses, and mechanism of action [1:15:30]; Ashwagandha: current evidence for its effects on sleep, stress, and anxiety [1:19:15]; Ashwagandha: evaluating supplement quality, safety profile, and the risk-reward balance [1:22:15]; The importance of using a structured evaluation framework to assess any supplement [1:26:30]; and More. Connect With Peter on Twitter, Instagram, Facebook and YouTube

Dana will be 54 on Mar 1st, 2025 and is 5'2 at 110 lbs.  She started IF on SEPT 5, 2023, after learning about it on a podcast focusing on Alzheimer's / dementia prevention/mitigation.  She was listening to that podcast b/c she lost both parents-in-law to this horrible disease. Within 1 week of starting IF, she remembers saying out loud to her husband, “I feel fantastic. I don't think I'll ever want to stop doing this.”  She never had a weight problem but suffered from a horrible sugar addiction and was raised on UPFs and LOVED sugar, especially chocolate, since she was 3 years old. Old.  She used sugar/chocolate and UPFs her whole life as a way to soothe, celebrate, comfort, connect, etc. and has struggled with emotional eating FOREVER.  Since she never really struggled much with her weight and didn't drink alcohol or smoke cigs, she always justified the emotional eating with, “No big deal - it's my one vice.”  However, her father died at 51 of a massive heart attack, as did his father and his brother, so CVD runs in her family.  On Easter of 2016, she had just binged her son's Easter candy. She was watching Dr Phil when she saw an episode about “SKINNY FAT” people - she had a significant epiphany and started a program called “28-day shred”, which was paleo eating and lost 10 lbs (going from 128-118), then took 1 day off and did another round losing six more lbs.  She only ate sugar in those 60 days once but was miserable and felt weak -she couldn't keep eating that way.  So she stopped and slowly started consuming too much sugar and UPFs again.  IF has helped her sugar cravings as well as a MILLION other NSV's.  Our Patreon Supporters Community -Join us!Please consider joining the Fasting Highway Patreon community. The feedback has been great for all who have joined. It has become an excellent add-on to our Patreon members' IF lifestyle, who enjoy a lot of bonus content to support them in living an IF life for as little as 0.16 cents a day For less than a cup of coffee a month, you can join and support your own health goals and meet like-minded people and get a lot of supportGraeme hosts Zoom meetings four times a month in the Northern and Southern hemispheres for members to come and get support for their IF lifestyle, which has proven very popular with our Patreon members.You will not find anywhere that provides that kind of support and accountability for just 0.16 cents a day. There are over 100 exclusive pieces of audio content for Patreon members to help you navigate your IF journey and get more accountability and support. Please go to www.patreon.com/thefastinghighway to see the benefits you get back and how to join. I strongly encourage you to do so for the price of a cup of coffee a month. Its a sound investment into your health.Graeme's best-selling book, The Fasting Highway, about his journey and how he did it, is available in paperback and Kindle at your local Amazon store. It is also available on audio at Applebooks, Kobo, Spotify, and many other audiobook platforms. Graeme can also be booked for one-on-one mentoring and coaching by going to www.thefastinghighway.com, clicking on get help, getting coaching, and booking a time. All times you see are in your local time zone.Disclaimer: Nothing in this podcast should be taken as medical advice. The opinions expressed herein are those of the host and guest only.

This week's topics include AI for mental illness, maternal death worldwide, CVD, education and income in the US, and sleep spindles and regain of consciousness.

For years, we've been conditioned to fear cholesterol—especially LDL. But the real problem isn't just LDL itself. The real issue? Inflammation. LDL becomes dangerous when it gets oxidized, triggering arterial damage and plaque buildup. This is why focusing only on total cholesterol or LDL isn't enough. If you really want to understand your true cardiovascular risk, here's what actually matters:

Oatmeal has long been considered a heart-healthy breakfast, but is it really as good for us as we think? In this episode, Jonathan and Sarah break down the great oat debate. First, they explore the different types of oats - instant, rolled, and steel-cut and how processing impacts their nutritional value. Then, they put oats to the test using continuous glucose monitors (CGMs), comparing instant to steel-cut, with and without toppings, to demonstrate how blood sugar works. Sarah also discusses wider debates around oats: Are pesticides a concern? Is oat milk as healthy as it claims? Finally, she shares the ultimate guide to choosing the healthiest oats - and for those who prefer alternatives, she's got delicious, nutrient-packed swaps to try.

THT 2025, AEDs in schools, PAD pain, wildfires and CVD, heart health in sexual minorities.

Welcome to the Plant-Based Canada Podcast. In this episode we are joined by Dr. Meaghan Kavanagh to chat about diet-disease relationships and translating nutrition knowledge into action for cardiovascular health.Meaghan is a Postdoctoral Fellow in the Department of Nutritional Sciences at the University of Toronto and the Clinical Nutrition and Risk Factor Modification Centre at St. Michael's Hospital, mentored by Dr. John Sievenpiper. Her research explores diet-chronic disease relationships through clinical trials, systematic reviews, meta-analyses, and epidemiology. Recipient of the CIHR-MSFSS award, she visited the CDC in Atlanta as a Guest Researcher to investigate the Portfolio Diet's cardiovascular benefits in the NHANES program.Meaghan is dedicated to translating her research into practical tools, including the PortfolioDiet.app, developed for cardiovascular disease prevention.Before her Ph.D., Meaghan was a project manager at the University of Toronto (2016-2020), researching dietary patterns and disease prevention with Dr. David Jenkins, and Clinical Coordinator for the STOP Sugars NOW Trial at St. Michael's Hospital (2019-2020) with Dr. John Sievenpiper. She completed her M.Sc. at the University of Guelph with Drs. Lindsay Robinson and Amanda Wright and her B.Sc. thesis with Dr. Alison Duncan.In 2025, Meaghan will continue as a Banting Postdoctoral Fellow with Dr. Frank Hu at the Harvard T.H. Chan School of Public Health.Resources:Global Burden of DiseaseGlobal Burden of Disease and Risk Factors, Lancet 2024Glenn A, et al., AJCN 2024Portfolio Diet Meta-Analysis BMJ Open - newspaper reliable reportingRepresentation of statins in the British newsprint media Dr. Meaghan Kavanagh's Socials:Twitter: @MeaghanKavanag1 LinkedInGoogle Scholar ResearchGatePlant-Based Canada's Socials:Instagram  (@plantbasedcanadaorg)Facebook (Plant-Based Canada, https://m.facebook.com/plantbasedcanadaorg/)Website  (https://www.plantbasedcanada.org/)X / Twitter @PBC_orgBonus Content from University of GuelphDo you want to take your plant-based knowledge to the next level? Stay tuned for a special promo code!The online Plant-Based Nutrition Certificate through Open Learning and Educational Support at the University of Guelph has everything you need to know about implementing a sustainable plant-based diet.Each course is just four weeks long and will guide you through essential topics including nutritional benefits, disease prevention, and environmental impacts. You can also customize your learning with unique courses such as Plant-Based Diets for Athletes and Implementing a Plant-Based Diet at Home.As the first university-level plant-based certificate in Canada, you'll explore currentSupport the show

This month is heart health month and is the leading cause of death, we need to know as much as about it as we can so we can avoid it. Cardiovascular disease (CVD) can be caused by multiple factors, - all those factors that I talk about every week, - inflammation, oxidative stress, insulin resistance, and more. Even Hormones like estrogen, testosterone, and cortisol play a critical role in cardiovascular health. Yes, Preventable!

Something I've become a lot more knowledgeable about after my training as a GP, is cholesterol. It's probably the most important measurement every primary care doctor should know about, along with measures of metabolic health like weight, insulin resistance and blood pressure, but perhaps the least well understood.On today's episode we do a deep dive into all things cholesterol and cardiovascular disease with Professor Kausik Ray, Professor of Public Health and Honorary Cardiologist at Imperial College London and President of the European Atherosclerosis Society, and perhaps the most knowledgeable person I could talk to on this subject who has both research and clinical expertise in this area. We define exactly what we're referring to when we say cardiovascular disease (CVD) and atherosclerosis. What that entails and why it's important, being the leading cause of death globally. We discuss the importance of cholesterol in the body. Without cholesterol there is no life. Cholesterol is the precursor to our hormones, it forms the structural components of our cells, and most of our cells are able to create the cholesterol we require hence why there is no nutritional need to consume cholesterol.And, hopefully at the end of this episode you'll learn more about why the trifecta of high cholesterol, inflammation and damage to the arteries leads to disease, what blood measurements we should all have to calculate our risk, including apolipoprotein-B containing lipoproteins, Non-HDL and Lp(a), as well as the strategies to reduce risk with drugs and lifestyle.I've done other episodes on specific foods and dietary patterns to reduce cholesterol, but this I think is a necessary episode to give the backdrop to why this is important for everyone to know their numbers.

Case Discussion 118: Omalizumab in CVD

Join Dr. Jannine Krause as she sits down with Dr. Tracy Gapin, MD, FACS—a leading expert in men's health optimization, longevity, and peak performance. With over 25 years of experience as a board-certified urologist, Dr. Gapin shares transformative insights into how advanced diagnostics, wearable technology, and personalized health programs can unlock your full potential. Whether you're an entrepreneur, executive, or athlete striving for sustainable, measurable health improvements, this episode is packed with actionable strategies and cutting-edge science. What You'll Learn: The Testosterone Crisis: Why testosterone (T) levels in men decrease by 1% each year. The alarming connection between low T levels and cardiovascular disease (CVD). Why traditional testosterone reference ranges aren't optimal for peak performance. The best labs to assess your health deeper than conventional tests. Advanced Diagnostics for Health Optimization: The critical tests for understanding the root causes of high cholesterol. How Dr. Gapin uses tools like the Oura ring and continuous glucose monitors (CGMs) to optimize sleep and metabolic health. How heart rate variability (HRV) reveals stress effects on your body. The Science of Peak Performance: How hormones and epigenetics unlock your full potential. Strategies to manage stress, improve sleep, and sustain energy for peak performance. The power of real-time health monitoring through wearable technology. Why you can't manage what you don't measure—and how tracking health metrics leads to success. About Dr. Tracy Gapin: Dr. Gapin is the founder of the Gapin Institute, where he helps high-performing individuals achieve peak performance through cutting-edge health programs. He is the author of Male 2.0 and Codes of Longevity and a featured speaker at top events, including NBC and Dave Asprey's Biohacking Conference. Resources and Offers: Access Dr. Gapin's Peak Launch Program for comprehensive health optimization: Email: doctracy@gapininstitute.com Website: GapinInstitute.com/launch Text “HEALTH” to 26786 for exclusive access. Connect with Dr. Tracy Gapin: LinkedIn: Dr. Tracy Gapin Instagram & Twitter: @DrGapin Facebook: Dr. Tracy Gapin YouTube: Dr. Tracy Gapin

Low-dose aspirin (LDA), typically prescribed at a dosage of 81 mg daily, is primarily used during pregnancy to prevent or delay the onset of preeclampsia. However, the question of whether to continue LDA postpartum is less clear and requires careful consideration of the benefits and risks associated with its use in the postpartum period. After all, the American College of Cardiology and American Heart Association recommend that low-dose aspirin use (75 to 100 mg/d) might be considered for the primary prevention of atherosclerotic CVD among select adults ages 40 to 70 years at higher CVD risk but not at increased risk of bleeding. Meanwhile, the 2022 US Preventive Services Task Force (USPSTF) recommendation notes that the decision to initiate daily aspirin therapy for primary prevention of cardiovascular disease (CVD) should be made on a case-by-case basis for adults ages 40 to 59 with a 10% or greater 10-year CVD risk. The recommendation applies to those without signs or symptoms of clinically evident CVD who are not at an increased risk of bleeding. So, does continuation of LDA after delivery reduce the persistence of, or development of, chronic hypertension. Is that evidence-based? The answer is both YES and NO. Listen in for details.

Heart disease is the leading cause of death and disability worldwide. Dr. Shapiro joins us to discuss the increase in cardiovascular disease mortality, the primary causes and risk factors associated with CVD, common treatment approaches, and advances in screenings for risk and new treatments. Read more about Dr. Shapiro at https://school.wakehealth.edu/faculty/s/michael-d-shapiro

This week we delve into preventive cardiology with noted world authority, Associate Professor of Pediatrics, Dr. Carissa M. Baker-Smith of Nemours Health. In the present era, what roles do environment and social determinants of health play in cardiovascular disease? How should practitioners take a family history and how has the family history evolved in modern times? How can clinicians be sure that they are not 'missing' factors when they are trying to screen for cardiovascular disease risk in their patients? What are a few practical changes in how we speak with patients that we can all make to improve our understanding of our patients and their families? An important conversation this week with Dr. Baker-Smith.https://doi.org/10.1007/s11883-024-01232-4

This week's topics include Medicare negotiation on drug price comparison, messaging to improve adherence to CVD medications, maternal cancer detection, and VILPA.

Did you know your liver health could be the secret to protecting your heart? Non-Alcoholic Fatty Liver Disease (NAFLD) is skyrocketing due to modern diets and lifestyles—and it's not just about your liver anymore. The hidden link between NAFLD and heart disease could put your health at serious risk.In this must-watch episode, I uncover:

Welcome to the Hot Topics podcast from NB Medical with Dr Neal Tucker. In this edition, we look at three new research papers.Firstly, can eating chocolate actually reduce our chance of type 2 diabetes? Sounds too good to be true... Secondly, could a blood test predict your 30-year cardiovascular risk? Finally, how does general practice access going digital affect minoritised ethnic populations? Look out next week for the second of our special interviews. We talk to Dr Katie Bramall-Stainer, chair of the GPC in England, about what does she hope general practice will look like in the future and the effects of collective action in England.ReferencesBMJ Chocolate vs diabetesNEJM 30 year CVD risk predictionBJGP Digitalising GP access and minoritised ethnic populationswww.nbmedical.com/podcast

Today we're going to talk about a new study called whose goal was to assess the “relationship of cardiorespiratory fitness (CRF) and Body Mass Index (BMI) on both cardiovascular disease (CVD) and all- cause mortality risk” by Nathan R Weeldreyer, Jeison C De Guzman, Craig Paterson, Jason D Allen, Glenn A Gaesser, and Siddhartha S Angadi. Get full access to Weight and Healthcare at weightandhealthcare.substack.com/subscribe

The gang is in the building celebrating the end of regular season CFB, title on line as Stu and CVD enter last weekend tied

Today's guest is Dr. Bradley Bale, a pioneering cardiologist and co-founder of the BaleDoneen Method.In this episode, we explore Brad's fearless approach to life, the driving force behind his groundbreaking practice, and dive into why he's willing to take a few arrows in the back for what he believes in.The BaleDoneen Method is a personalized approach to preventing and managing heart attacks, strokes, and cardiovascular disease (CVD). It focuses on identifying and treating the root causes of arterial disease rather than just addressing risk factors like high blood pressure or cholesterol.ResourcesFollow your curiosity, connect, and join our ever-growing community of extraordinary minds.CariFree WebsiteCariFree on InstagramCariFree on FacebookCariFree on PinterestThe BaleDoneen Method WebsiteBeat the Heart Attack GeneThe Bezos BlueprintThe Biology of KindnessWhat's In This EpisodeBrad's motivation for taking a few arrows in the back.Why the cardiovascular status quo isn't good enough.The financial incentives of late-stage treatment and not prevention.The power of optimistic thinking.

Guest picker Joe Bags joins me and CVD for week 13 plays

In this episode, Dr. Brendan Everett discusses how lifestyle changes can reduce low-grade systemic inflammation. He explores the impact of weight loss on high-sensitivity CRP (hs-CRP)levels, the benefits of different diet types, and the role of exercise and smoking cessation in managing inflammation. Watch now to learn how lifestyle interventions can play a crucial role in reducing inflammation and improving cardiovascular health.

This is a high energy conversation with renowned preventative cardiologist Dr Ross Walker and fx Medicine by BioCeuticals ambassador Dr Michelle Woolhouse. Dr Walker makes the specialist field of preventative cardiology accessible; he does this through his use of insightful explanations and well-crafted analogies from his 45 years of practice. Coenzyme Q10 (CoQ10) and its active form ubiquinol, take centre stage in this discussion, including Dr Ross Walker's use of ubiquinol in cardiovascular disease (CVD), how ubiquinol can be used to reduce the side effects associated with statins, and the research showing CoQ10/ubiquinol to decrease all-cause mortality. Dr Walker talks much more than just ubiquinol, including the importance of measuring calcium coronary artery score in assessing cardiovascular risk, his well-tested protocol for lipoprotein (a), diabobesity and the impact of insulin resistance, and his not to be missed five keys of being healthy. There are practice pearls a plenty: when statins are necessary, the importance of lifestyle and diet interventions for heart health, and the real pandemic of our time; diabobesity. Find today's transcript and show notes here: https://www.bioceuticals.com.au/education/podcasts/ubiquinol-s-role-in-preventative-cardiology-with-dr-michelle-woolhouse-and-dr-ross-walker Sign up for our monthly newsletter for the latest exclusive clinical tools, articles, and infographics: https://pages.blackmores.com.au/FXM-signup.html ***DISCLAIMER: The information provided on fx Medicine by BioCeuticals is for educational and informational purposes only. The information provided is not, nor is it intended to be, a substitute for professional advice or care. Please seek the advice of a qualified health care professional in the event something you learn here raises questions or concerns regarding your health.***

The Filtrate:Joel TopfSwapnil HiremathWith Special Guest:Michelle Hladunewich, Nephrologist at the University of TorontoMir Melamed, Maternal-Fetal Medicine at the University of TorontoEditor Simon TopfShow NotesPriscilla Smith's letter:Dear Joel and the Freely Filtered team,I am a long-time fan of your podcast and was looking forward to hearing your recently aired discussion of the Praecis study of sflt1:PlGF use in preeclampsia. Preeclampsia and renal disease in pregnancy are areas that many nephrologists report a lack of knowledge or confidence in discussing and managing. I am a nephrologist who has been co-leading a renal pregnancy clinic in London while writing a PhD on progression of renal disease in pregnancy. I have had the immense privilege of working with experts and key opinion leaders in preeclampsia research both in the UK and internationally. As you know, preeclampsia is a serious and significant condition contributing to global maternal mortality and is also associated with future CKD and CVD risk so is both relevant and important within our professional group.Sadly, I found myself disappointed by the episode and felt it was a missed opportunity. I appreciate that you had difficulties obtaining appropriate experts to join the discussion, but perhaps it would have been better to delay production. While you all valiantly proceeded to discuss this important study, the topic is complex and there appeared to be a lack of understanding of the surrounding literature and pathogenesis of preeclampsia. Sadly, the maternal medicine expert's comments at the end of the podcast added little as she seemed determine to negate any benefit from the results despite declaring she had no experience or expertise in the use of these biomarkers.There are many people who understand the clinical aspects of preeclampsia as well as having direct experience of the use and utility of these biomarkers who would have been able to contribute much to your conversation. I look forward to future discussions of renal disease in pregnancy on your podcast and would be happy to suggest some expert panellists if you ever find yourself stuck.Kind regards,Priscilla Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsia (JCI 2003)sFlt background: Pathogenesis of Preeclampsia and Therapeutic Approaches Targeting the Placenta (PubMed)PlGF background: Perspectives on the Use of Placental Growth Factor (PlGF) in the Prediction and Diagnosis of Pre-Eclampsia: Recent Insights and Future Steps (PubMed)The PRAECIS trial (NephJC | NEJM Evidence)

Myself and CVD have picks along with absentee ballots from bobcat and Roberto

Evaluation and Credit:  https://www.surveymonkey.com/r/Medchat72 Target Audience This activity is targeted toward primary care physicians and advanced providers. Statement of NeedAdolescents with Type 1 diabetes mellitus (T1DM) face a significantly higher risk of developing cardiovascular disease (CVD) compared to their peers without diabetes. Regular physical activity is crucial for these young individuals, as it helps mitigate CVD risk and improves cardiorespiratory fitness (CRF). Therefore, promoting lifelong physical activity, with appropriate insulin and dietary adjustments, is essential for managing T1DM and preventing CVD. This podcast will highlight the benefits of exercise in preventing cardiovascular disease, describe the advantages of sports activities, and outline clinical guidelines for safe exercise practices in adolescents with T1DM. Objectives At the conclusion of this offering, the participant will be able to:  Discuss the benefits of exercise in the management of adolescent patients with Type 1 diabetes.  Describe potential glycemic management strategies during times of sport/activity in adolescents with Type 1 diabetes. Review the role of technology and future advancements in the management of diabetes.  Moderator Mark McDonald, M.D., MHA, CPE System Vice President Pediatric Medical Affairs Medical Director, Norton Children's Louisville, Kentucky  Professor Department of Pediatrics Division of Critical Care UofL School of Medicine Louisville, Kentucky Speaker Brad Thrasher, D.O., MBAPediatric Endocrinologist Medical Director, Pediatric Diabetes Medical Director, Sport & Activity Wendy Novak Diabetes Institute Norton Children's Endocrinology Louisville, Kentucky Associate Professor UofL School of Medicine Louisville, Kentucky    Moderator, Speaker and Planner Disclosures  The planners, moderator and speaker of this activity do not have any relevant financial relationships with ineligible companies to disclose.   Commercial Support  There was no commercial support for this activity.  Physician Credits Accreditation Norton Healthcare is accredited by the Kentucky Medical Association to provide continuing medical education for physicians. Designation Norton Healthcare designates this enduring material for a maximum of .50 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.   For more information about continuing medical education, please send an email to cme@nortonhealthcare.org.  Nursing CreditaNorton Healthcare Institute for Education and Development is approved with distinction as a provider of nursing continuing professional development by the South Carolina Nurses Association, an accredited approver by the American Nurses Credentialing Center's Commission on Accreditation. This continuing professional development activity has been approved for .50 contact hours. In order for nursing participants to obtain credits, they must claim attendance by attesting to the number of hours in attendance.   For more information related to nursing credits, contact Sally Sturgeon, DNP, RN, SANE-A, AFN-BC at (502) 446-5889 or sally.sturgeon@nortonhealthcare.org. Resources for Additional Study/References Chang, Xinyi, et. Al.  “Effect of Physician Activity/Exercise on Cardiorespiratory Fitness in Children and Adolescents with Type I Diabetes: A Scoping Review”; International Journal of Environmental Research and Public Health, Jan. 12, 2023; https://doi.org/10.3390/ijerph20021407 Cockcroft et al. “Factors affecting the support for physical activity in children and adolescents with type 1 diabetes mellitus: a national survey of health care professionals' perceptions”; BMC Pediatrics (2023) 23:131. https://doi.org/10.1186/s12887-023-03940-3   Date of Original Release | Nov. 2024; Information is current as of the time of recording. Course Termination Date | Nov. 2026 Contact Information | Center for Continuing Medical Education; (502) 446-5955 or cme@nortonhealthcare.org Also listen to Norton Healthcare's podcast Stronger After Stroke. This podcast, produced by the Norton Neuroscience Institute, discusses difficult topics, answers frequently asked questions and provides survivor stories that provide hope. Norton Healthcare, a not for profit health care system, is a leader in serving adult and pediatric patients throughout Greater Louisville, Southern Indiana, the commonwealth of Kentucky and beyond. More information about Norton Healthcare is available at NortonHealthcare.com.

Join Kate, Gary, Henry and Mark as they discuss a new therapy for dry eye syndrome, antibiotics for suspected UTI in adults with delirium, a new ACG guideline for treating H pylori, and the prevalence of knee pathology in asymptomatic adults. See below for links to the articles and other stuff: Dry eye treatment BMJ: https://www.bmj.com/content/386/bmj-2024-080474 Patient instructions: https://www.bmj.com/content/bmj/suppl/2024/09/11/bmj-2024-080474.DC1/liji080474.ww2.pdf Antibiotics for UTI in delirium: https://pubmed.ncbi.nlm.nih.gov/38895992/ ACG guideline for H. Pylori: https://pubmed.ncbi.nlm.nih.gov/28071659/ MRI of asymptomatic knees: https://pubmed.ncbi.nlm.nih.gov/32060622/ Elections and CVD: https://pmc.ncbi.nlm.nih.gov/articles/PMC9021908/

In this episode of Sugar Crush, host, Dr. Rick Jacoby, discusses the implications of ultra-processed foods on cardiovascular disease (CVD) based on a literature review by Dr. Joanne Manson. While highlighting that 60-70% of the U.S. diet comprises these foods, he critiques the inconclusive findings regarding their health impacts. Manson's analysis indicates a significant risk increase for heart disease and stroke linked to high intake. Jacoby argues that all ultra-processed foods contribute negatively to health, proposing a need for clearer messaging on their dangers. He emphasizes the role of sugar in chronic diseases and promotes his book, "Unglued," which addresses the effects of sugar and potential remedies.

Just The Inserts isn't anonymous anymore… today we're introducing Alexandra to you, and you're getting to see her face for the first time.This is our second interview with her (first episode linked below). In this interview we go even deeper than the first time, discussing the RSV shot the CVD/flu shot mash-up, mRNA products, and a hard look at the Vitamin K product that babies get on their first day of life.As always in conversation with Alexandra, informed consent is paramount. We speak to the value of people being provided with all the information they need in order to make an informed decision, and discuss the need for that decision to be respected regardless of what that decision ends up being.Order sets/standing orders are discussed in detail, the impact of 2020 on the medical community at large, and the relationship between authority and responsibility is fully dissected.We end talking a bit more about her new book, Well Considered, a wonderful informed consent resource.This is a CAN'T MISS episode that you'll want to be sure to share.LINK TO OUR FIRST INTERVIEW WITH JUST THE INSERTS: https://open.spotify.com/episode/3zTX4nvx0Xg8H3xAHalnCU?si=jiez05NeTAuz7KODRd2ExgGUEST:Alexandra of Just The Insertshttps://www.justtheinserts.comhttps://justtheinserts.store (get her book here)https://www.instagram.com/justtheinserts?igsh=MTBhNDY3amVwNmVpNg==SPONSORS:Pure Anada:https://www.pureanada.caRowe Casa:Use code BOOMCLAP to save 20% off your first order!https://www.rowecasaorganics.com/?sca_ref=3468709./2CVRBIBV1RMDY Collective Homeopathy:BOOMCLAP to save 10% as you try out homeopathy for yourself!https://rmdycollective.com/boomclappodcastFIND US / SUPPORT THE PODCAST: https:theboomclappodcast.square.sitewww.instagram.com/boomclappodcastwww.instagram.com/cecily.dickey www.instagram.com/ritarogersco

His own official show every week CVD giving out his week 5 picks

Why do we so often act like cleaning up garbage, stopping crime, and solving our health crisis is some kind of mystery that can never be solved? How come other countries seem to have it figured out, if not perfected, though that is slowly changing too. Obesity is a growing concern globally, where traditional lifestyles and diets are being replaced by an exported one that consists of ultra-hyper-processed and refined so-called foods. We are paying for convenience with our lives, and considering that those aged 20-30 spend upwards of 30 hours a week using their phones for recreational purposes, there is zero excuse we are unable to do better with our health. We often have the time but budget it poorly. Now we are reading about 17 cancers targeting Millennials and Gen-x, and the public response is to blame SARS-COV-2, or the m.R.N.A therapy. Sure, there is a discussion here to be had. But cancer rates have been exploding with waistlines for decades. The American Cancer Society estimates in a recent report that 40% of all cancers in 30-year and older adults are entirely preventable with a few lifestyle modifications: smoking, weight, alcohol, and physical inactivity. Interestingly, these are the same factors according to the World Heart Federation contributing to CVD. Cardiovascular Disease is nearly 80% preventable when addressing these factors. Instead of focusing on reality, nearly every side of nearly every group identity attacks these facts and demands new drugs, surgeries, and magic potions. Politicians with drug company money in their pocket attack the drug companies and pretend to negotiate cheaper costs for drugs that should be limited in consumption to begin with. Now with the excessive compulsive consumption of such substances we are decades away from any potential reversal of this issue even if we immediately reversed course now. -FREE ARCHIVE & RSS: https://www.spreaker.com/show/the-secret-teachings Twitter: https://twitter.com/TST___Radio Facebook: https://www.facebook.com/thesecretteachings WEBSITE (BOOKS, RESUBSCRIBE for early show access): http://thesecretteachings.info Paypal: rdgable@yahoo.com CashApp: $rdgable EMAIL: rdgable@yahoo.com / TSTRadio@protonmail.com

This week's topics include semaglutide and mortality, beta blockers after MI, FIT test comparison, and 30-year CVD prediction with a blood test in women.

In episode 583, Mike and James continue to go over the issues associated with using CVD risk calculators. We talk about some of the limitations, how to think about the results and explain the risks and benefits to patients. Show notes PEER Simplified Cardiovascular Decision Aid Incorporation of Shared Decision-Making in International Cardiovascular Guidelines, 2012-2022 […]

CardioNerds Cardio-Rheumatology Series Co-Chairs Dr. Rick Ferraro, Dr. Gurleen Kaur, and Episode Lead Dr. Ronaldo Correa discuss “The Role of Inflammation in Cardiovascular Disease” with Dr. Antonio Abbate. Join the CardioNerds as they kick off the Cardio-Rheumatology series with Dr. Antonio Abbate. In this episode, Dr. Abbate, a leading expert in cardio-immunology, discusses the role of inflammation in cardiovascular disease. We explore the molecular mechanisms linking inflammation to atherosclerosis, the impact of chronic low-grade systemic inflammation on heart disease, and potential therapeutic targets. Dr. Abbate shares insights on how genes and lifestyle factors contribute to inflammation, the use of inflammatory markers in clinical practice, and emerging anti-inflammatory therapies in atherosclerotic cardiovascular disease. Tune in for an enlightening conversation on the intersection of inflammation and cardiovascular health. Dr. Ronaldo Correa drafted the notes. Episode audio was engineered by Dr. Amit Goyal. CardioNerds Prevention PageCardioNerds Episode PageCardioNerds AcademyCardionerds Healy Honor Roll CardioNerds Journal ClubSubscribe to The Heartbeat Newsletter!Check out CardioNerds SWAG!Become a CardioNerds Patron! Pearls - Cardio-Rheumatology: The Role of Inflammation in Cardiovascular Disease Inflammation is key in the pathogenesis and progression of atherosclerosis. Estimating systemic inflammation is part of a comprehensive preventive assessment (primary/secondary). Patients with autoimmune inflammatory diseases are at a higher risk for cardiovascular events. C-reactive protein (CRP) can estimate systemic inflammation and help assess residual inflammatory risk in patients with traditional intermediate/low cardiovascular disease, guiding management consideration with lipid-lowering therapy, aspirin, and colchicine. The pharmacological management of atherosclerosis is evolving beyond primarily lipid-lowering therapies to focus on targeting the underlying residual inflammatory process. Colchicine (inflammasome blocker as an anti-mitotic drug) is approved for use in chronic stable CVD in selected cases, and interleukin pathway blockers, especially IL-1 and IL-6, are under clinical trial investigation. First things first! Prioritize treating and optimizing traditional risk factors and comorbidities and emphasize lifestyle modifications to reduce cardiovascular disease (control diabetes and hypertension, reduce or cease smoking/alcohol, lose weight, and engage in regular physical activity). They all impact inflammation directly or indirectly Show notes - Cardio-Rheumatology: The Role of Inflammation in Cardiovascular Disease Notes: Notes drafted by Dr. Ronaldo Correa. What is the link between inflammation and cardiovascular atherosclerosis? Inflammation is involved both in the pathogenesis and progression of atherosclerosis.Histopathological coronary atherosclerosis studies have demonstrated the presence of inflammatory mediators as well as a central role of factors of innate immunity such as macrophages and T cells which can interact with vascular smooth muscle cells in the progression of atherosclerotic plaque.Patients with autoimmune inflammatory conditions have earlier and higher cardiovascular event rates (accelerated atherosclerosis due to residual inflammatory risk). Elevated inflammatory markers (for example, high CRP) predict cardiovascular events. How should inflammation be considered in the context of residual cardiovascular risk? Inflammation may be the inciting factor in atherosclerosis, or it may amplify the process driven primarily by other risk factors. Therefore, treating the comorbidities and traditional CVD contributors is key to reducing the vicious inflammatory cycle.Assessing residual risk using inflammatory markers can assist in management. C-reactive protein (CRP) can estimate systemic inflammation and help assess re...

In episode 582, Mike and James go over the issues associated with using CVD risk calculators. We talk about where the numbers come from, what they mean, what their limitations are, how to think about them and how to use them. So have a listen as it may decrease your risk but it will definitely […]

CardioNerds Dan Ambinder and Dr. Devesh Rai join cardiology fellows and National Lipid Association lipid scholars Dr. Oby Ibe from Temple University and Dr. Elizabeth Epstein from Scripps Clinic. They discuss a case involving a patient with elevated Lp(a). Dr. Jessica Pena provides expert commentary. Drs. Oby Ibe and Elizabeth Epstein drafted notes. CardioNerds Intern Christiana Dangas engineered episode audio. This episode is part of a case reports series developed in collaboration with the National Lipid Association and their Lipid Scholarship Program, with mentorship from Dr. Daniel Soffer and Dr. Eugenia Gianos. This is a 63-year-old man with hypertension, hyperlipidemia, and active tobacco smoking who presented with acute dyspnea. He was tachycardic but otherwise initially hemodynamically stable. The physical exam demonstrated warm extremities with no murmurs or peripheral edema. Chest X-ray revealed diffuse pulmonary edema, and the ECG showed sinus tachycardia with T-wave inversions in the inferior leads. A bedside echocardiogram revealed a flail anterior mitral valve leaflet. The patient was taken for cardiac catheterization that revealed nonobstructive mid-RCA atheroma with a distal RCA occlusion, which was felt to reflect embolic occlusion from recanalized plaque. PCI was not performed. Right heart catheterization then demonstrated a low cardiac index as well as elevated PCWP and PA pressures. An intra-aortic balloon pump was placed at that time. A TEE was performed soon after which showed the posteromedial papillary muscle was ruptured with flail segments of the anterior mitral leaflet as well as severe posteriorly directed mitral regurgitation. The patient ultimately underwent a successful tissue mitral valve replacement and CABG. US Cardiology Review is now the official journal of CardioNerds! Submit your manuscript here. CardioNerds Case Reports PageCardioNerds Episode PageCardioNerds AcademyCardionerds Healy Honor Roll CardioNerds Journal ClubSubscribe to The Heartbeat Newsletter!Check out CardioNerds SWAG!Become a CardioNerds Patron! Pearls - Little (a), Big Deal – National Lipid Association You are never too young to see a preventive cardiologist! The field of preventive cardiology is shifting focus towards the identification of early upstream risk and intervention before the development of clinical ASCVD (1,5). Patients who have a strong family history of cardiovascular disease, a personal history of CVD at an early age, multiple risk factors, or genetic disorders such as familial hypercholesterolemia especially benefit from early cardiovascular risk assessment and reduction. Female-specific risk factors to incorporate into a young woman's cardiovascular risk assessment include polycystic ovarian syndrome, hormone contraceptive use, early menarche (age 5 pregnancies), early menopause (age

View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter's Weekly Newsletter Isaac "Zak" Kohane, a pioneering physician-scientist and chair of the Department of Biomedical Informatics at Harvard Medical School, has authored numerous papers and influential books on artificial intelligence (AI), including The AI Revolution in Medicine: GPT-4 and Beyond. In this episode, Zak explores the evolution of AI, from its early iterations to the current third generation, illuminating how it is transforming medicine today and unlocking astonishing possibilities for the future. He shares insights from his unconventional journey and early interactions with GPT-4, highlighting significant AI advancements in image-based medical specialties, early disease diagnosis, and the potential for autonomous robotic surgery. He also delves into the ethical concerns and regulatory challenges of AI, its potential to augment clinicians, and the broader implications of AI achieving human-like creativity and expertise. We discuss: Zak's unconventional journey to becoming a pioneering physician-scientist, and his early interactions with GPT-4 [2:15]; The evolution of AI from the earliest versions to today's neural networks, and the shifting definitions of intelligence over time [8:00]; How vast data sets, advanced neural networks, and powerful GPU technology have driven AI from its early limitations to achieving remarkable successes in medicine and other fields [19:00]; An AI breakthrough in medicine: the ability to accurately recognize retinopathy [29:00]; Third generation AI: how improvements in natural language processing significantly advanced AI capabilities [32:00]; AI concerns and regulation: misuse by individuals, military applications, displacement of jobs, and potential existential concerns [37:30]; How AI is enhancing image-based medical specialties like radiology [49:15]; The use of AI by patients and doctors [55:45]; The potential for AI to augment clinicians and address physician shortages [1:02:45]; The potential for AI to revolutionize early diagnosis and prediction of diseases: Alzheimer's disease, CVD, autism, and more [1:08:00]; The future of AI in healthcare: integration of patient data, improved diagnostics, and the challenges of data accessibility and regulatory compliance [1:17:00]; The future of autonomous robotic surgery [1:25:00]; AI and the future of mental health care [1:31:30]; How AI may transform and disrupt the medical industry: new business models and potential resistance from established medical institutions [1:34:45]; Potential positive and negative impacts of AI outside of medicine over the next decade [1:38:30]; The implications of AI achieving a level of creativity and expertise comparable to exceptional human talents [1:42:00]; Digital immortality and legacy: the potential to emulate an individual's personality and responses and the ethical questions surrounding it [1:45:45]; Parting thoughts [1:50:15]; and More. Connect With Peter on Twitter, Instagram, Facebook and YouTube

In today's episode, our hosts delve into a recent study that investigates the correlation between olive oil and dementia. They meticulously assess the overall quality of the study, providing insights into why its findings are accurate. The episode then shifts focus to the dramatization often seen in media surrounding such studies. Our hosts discuss the dangers of oversimplified and one-size-fits-all health advice commonly found online. Humans are diverse and incredibly nuanced, and it's time we celebrate this diversity rather than offering the masses quick health hacks. They emphasize that while olive oil is often touted for its health benefits, it is not a whole food; it's highly processed and caloric. Our hosts share real patient stories and their own olive oil habits, adding a personal touch to the discussion. Tune in to gain a deeper understanding of the complexities behind health studies and the importance of individualized health advice. Ideas: Fish oil and CVD (https://www.webmd.com/vitamins-and-supplements/news/20240522/fish-oil-supplements-linked-to-first-time-heart-problems) Olive Oil and health (https://www.webmd.com/alzheimers/news/20240507/cm/olive-oil-may-lower-risk-of-dementia-related-death) Female doctors are better (https://www.webmd.com/women/news/20240501/are-female-doctors-better-heres-what-to-know) 60% of people will have CVD after 2050 (https://www.healthline.com/health-news/most-americans-will-have-cardiovascular-disease-by-2050) increased stroke in young individuals (https://www.healthline.com/health-news/most-americans-will-have-cardiovascular-disease-by-2050) Dangers of sweeteners: (https://www.medicalnewstoday.com/articles/262475) Dangers of mushroom chocolates (https://www.cnn.com/2024/06/10/health/fda-warning-diamond-shruumz-microdosing-chocolate/index.html) Brain (worm) parasites  

My omega-3 guide on concerns like a-fib, dosage, supplement quality, oxidation, and more Discover my premium podcast, The Aliquot Join over 300,000 people and sign up for my newsletter Become a FoundMyFitness premium member to get access to exclusive episodes, emails, live Q+A's with Rhonda and more In this special solo episode of FoundMyFitness, we're taking a deep dive into alcohol. We'll explore the science, misconceptions, controversies, and health effects of this widely used drug. I believe that a nuanced, scientific discussion on alcohol is the best way to provide you with the information you need to make an informed decision about alcohol use. Timestamps (00:00) Introduction (08:03) What does it mean to "have a drink"? (09:39) Drinking frequency definitions (12:39) How alcohol is metabolized (18:25) Can alcoholism be inherited? (19:41) How food affects alcohol metabolism (21:40) Does age affect alcohol metabolism? (22:29) How alcohol affects nutrient absorption (27:04) How alcohol affects gut health (28:57) Alcohol elevates circulating LPS levels (31:51) Gut health & alcohol use disorders (36:30) Sick quitter & healthy user biases (39:38) How alcohol impacts the brain (43:34) Alcohol's effects on anxiety (49:56) Alcohol facilitates thiamine deficiency (51:39) Alcohol promotes brain inflammation (52:56) Dementia & Alzheimer's disease risk  (1:06:50) Is resveratrol in red wine beneficial? (1:11:28) How alcohol impacts sleep (1:19:47) Mitigating alcohol's impact on sleep  (1:22:13) Hangover symptoms & causes (1:26:33) How congeners affect hangover severity (1:27:58) Treating hangovers with fruit (1:30:40) Zinc, vitamin B3, & hangovers (1:31:41) Managing hangovers with NSAIDs (1:32:22) "Hair of the dog” for hangovers (1:32:40) Liposomal glutathione, NAC, & hangovers (1:35:56) Does ZBiotics prevent hangovers? (1:38:18) Dihydromyricetin (DHM) for hangovers (1:39:15) Exercise & sauna for treating hangovers (1:40:21) Alcohol's effect on mortality risk  (1:44:28) Alcohol consumption in Blue Zones (1:49:07) Does alcohol increase cancer risk? (2:00:43) Can quitting alcohol lower cancer risk? (2:09:46) Alcohol & cardiovascular disease (CVD) (2:23:24) Alcohol and type 2 diabetes risk (2:28:28) Alcohol's impact on your waistline (2:31:33) Why alcohol facilitates weight gain (2:34:06) How alcohol impacts reproductive health (2:44:31) Preconception alcohol risks (2:47:12) How alcohol affects testosterone in men (2:48:55) Pre-pregnancy alcohol consumption risks (2:53:17) Is red wine the healthiest option? (2:57:47) Alcohol & post-exercise recovery (3:01:34) Does alcohol "blunt your gains"? (3:04:11) The BEER-HIIT study (3:05:03) Can exercise lessen alcohol cravings? (3:12:57) Alcohol damage control tactics Show notes are available by clicking here Watch this episode on YouTube

Cardiovascular disease is the global leading cause of death and was responsible for more than 15 million fatalities in 2016.    What would you do to prevent yourself and your loved ones from becoming part of that statistic?   Today's guest, Dr. Joel Kahn, says it's as simple as plant-based nutrition.   Dr. Kahn is one of the world's top cardiologists, a restaurateur, and is known as America's Healthy Heart Doc. He's committed to making the world healthier through the preventative and healing power of plants.   He joins Dotsie and Alexandra to discuss the different factors that can lead to cardiovascular disease and the solutions to prevent or reverse early symptoms.    Tune in to hear what this vegan doctor has learned in his almost 40 years of practice, his advice for protecting yourself against fatal diseases, and his tips for living a healthier lifestyle.   “A healthy plant-based lifestyle puts the power back in the patients—where it should be.” - Dr. Joel Kahn   What we discuss in this episode: - What disrupts hormone patterns and influences our health? - How Dr. Dean Ornish's paper on getting rid of plaque through exercise and a plant-based diet has affected the views of the medical community - The effects of inflammation and its connection to CVD, as studied and explained by Rudolph Virchow - Why you need to include high-sensitivity C-reactive protein in your routine blood work - Sugar and Type II Diabetes: Why was Dr. Neal Barnard criticized for his statements in What the Health? - Dr. Kahn's diet advice, including using Chronometers and resources from Chef AJ and Dr. Susan Pierce Thompson - Resources to live a healthier lifestyle, including Dr. Michael Greger's book How Not to Die and his talk at Plant-Based Nutrition Support Group   Resources: - Dr. Joel Kahn: https://www.drjoelkahn.com/ - Instagram: Dr. Joel Kahn, MD (@drjkahn) - https://www.instagram.com/drjkahn/ - Facebook: Dr. Joel Kahn - https://www.facebook.com/drjoelkahn - X: @drjkahn - https://x.com/drjkahn   ★☆★ Help us remove dairy from the Dietary Guidelines for Americans! ★☆★ https://switch4good.org/dietary-guidelines-for-americans-2025/ ★☆★ Click the link below to support the ADD SOY Act! ★☆★ https://switch4good.org/add-soy-act/ ★☆★ Share the website and get your resources here ★☆★ https://kidsandmilk.org/ ★☆★ Send us a voice message and ask a question. We want to hear from you! ★☆★ https://switch4good.org/podcast/ ★☆★ Dairy-Free Swaps Guide: Easy Anti-Inflammatory Meals, Recipes, and Tips ★☆★ https://switch4good.org/dairy-free-swaps-guide ★☆★SUPPORT SWITCH4GOOD★☆★ https://switch4good.org/support-us/ ★☆★ JOIN OUR PRIVATE FACEBOOK GROUP ★☆★  https://www.facebook.com/groups/podcastchat ★☆★ SWITCH4GOOD WEBSITE ★☆★ https://switch4good.org/ ★☆★ ONLINE STORE ★☆★ https://shop.switch4good.org/shop/ ★☆★ FOLLOW US ON INSTAGRAM ★☆★ https://www.instagram.com/Switch4Good/ ★☆★ LIKE US ON FACEBOOK ★☆★ https://www.facebook.com/Switch4Good/ ★☆★ FOLLOW US ON TWITTER ★☆★ https://twitter.com/Switch4GoodOrg ★☆★ AMAZON STORE ★☆★ https://www.amazon.com/shop/switch4good ★☆★ DOWNLOAD THE ABILLION APP ★☆★ https://app.abillion.com/users/switch4good

View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter's Weekly Newsletter In this “Ask Me Anything” (AMA) episode, Peter provides insights on a broad range of important topics. He delves into the prevention of cognitive decline, the link between cardiovascular disease and Alzheimer's disease, and methods to lower blood glucose, insulin, and apoB. He also addresses nutrition-related queries, exploring the impact of dietary habits on weight loss and longevity, how a person can identify the best diet for themselves, and common nutrition myths. Additional discussions include optimal blood pressure, daily step goals, the benefits of standing versus sitting desks, and much more. If you're not a subscriber and are listening on a podcast player, you'll only be able to hear a preview of the AMA. If you're a subscriber, you can now listen to this full episode on your private RSS feed or our website at the AMA #60 show notes page. If you are not a subscriber, you can learn more about the subscriber benefits here. We discuss: Overview of topics and episode format [1:40]; Preventing cognitive decline [5:00]; How to lower blood glucose and insulin [13:30]; The relationship between lipids, CVD, and Alzheimer's disease, and whether statins can increase the risk of neurodegenerative disorders and AD [23:15]; Reducing apoB levels through exercise and diet [31:45]; Pharmacological options for lowering apoB [38:00]; How nutrition impacts longevity via metabolic health, muscle mass, BMD and more [40:15]; How can someone determine the best diet for themselves? [43:45]; Nutrition myth: All weight loss is good [46:45]; Nutrition myth: Metabolic rates are dramatically different among individuals based on genetics [49:00]; Nutrition myth: Losing weight after a brief period of overeating is impossible [53:45]; Nutrition myth: GLP-1 agonists are a replacement for a healthy lifestyle [57:45]; Nutrition myth: There is a single best diet for weight loss [1:03:00]; Nutrition oversimplification: All calories are created equal [1:05:45]; Daily step goals [1:06:45]; The benefits of standing versus sitting throughout the day [1:10:45]; How to identify the most impactful and easiest-to-implement ways to improve your health [1:12:30]; The critical importance of emotional health [1:14:30]; Why supplements should be considered as supportive aids rather than primary solutions in one's strategy to improve longevity [1:18:00]; Strategies for reducing high blood pressure [1:20:45]; Peter's biggest frustrations with "mainstream health advice" [1:28:00]; Peter's chaotic, yet cherished, morning routine [1:31:00]; and More. Connect With Peter on Twitter, Instagram, Facebook and YouTube