Podcasts about cvd

Tune into this podcast from Dr Clíona Ní Cheallaigh to learn how to provide person-centered care for treatment-experienced people with HIV. Gain strategies to address each individual's specific history and needs while considering the potential impact of comorbidities and other health challenges. Topics covered include:Individualizing Antiretroviral Regimens for Treatment-Experienced People With HIVStrategies to Improve Adherence and Addressing Barriers to Engagement in CarePerson-Centered, Trauma-Informed CareResistance Testing in the Setting of Virologic FailureSelection of ARVs With a Failing RegimenPresenters:Clíona Ní Cheallaigh, MB, MRCP, PhDConsultant PhysicianInclusion Health ServicesSt James's Hospital DublinAssociate ProfessorDepartment of MedicineTrinity College DublinDublin, IrelandLink to full program:https://bit.ly/4oiYxExGet access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Stress isn't just something to “manage” — it's a signal, a teacher, and often, an invitation to look deeper at our health, our choices, and our lives. In this solo episode, Darin reframes stress not as an enemy, but as a dashboard light pointing toward misalignments in our nervous system, environment, relationships, and purpose. Drawing on science, practical tools, and personal insight, Darin reveals how layered stress silently drains our vitality — and how to transform it into an ally for growth, healing, and deeper contentment. Whether it's hidden trauma, toxic environments, unresolved conflict, or the modern distractions constantly pulling at our attention, Darin lays out a roadmap to stop the leaks and reclaim the energy already within you. This episode is a powerful reminder: stress isn't the end of the story — it's the beginning of awareness, safety, and a super life.     What You'll Learn in This Episode [00:00] Introduction to the Super Life podcast [03:27] Why stress might not be your enemy [04:17] Stress as an ally: the signals it gives us about misalignment [04:32] The dashboard light metaphor: how stress reveals hidden issues [05:28] The illusion of “no choice” and the infinite possibilities always available [06:12] Global stress statistics and why most people underestimate their stress load [07:23] Hidden stress revealed through heart rate variability and physiology [08:23] Layered stress: how sleep, exercise, and poor choices compound each other [09:25] Safety vs. calm — why your nervous system craves safety first [10:15] Trauma and the unconscious mind: how old wounds drive our stress response [11:54] Inner narratives and negative self-talk as hidden stress multipliers [12:22] The role of community and your social field in stress and resilience [13:53] Relationships, honesty, and how your circle shapes your energy [14:55] Why boundaries around media and politics are vital for mental clarity [17:42] Finding micro-purpose when life feels overwhelming [18:52] Environmental layers of stress — light, air, and clutter [19:15] The existential layer: stress from living without service or purpose [20:12] Stress as a risk amplifier — how it undermines healing and health [20:55] The deeper truth of safety, connection, and higher power [23:00] Practical tools: breathing, grounding, nature, and conscious choices [24:01] Trauma reframed: not a problem, but a protector at the time [25:25] Lessons from Peter Levine and wild animals: releasing trauma physically [26:04] Questions to ask trauma: “What are you protecting me from?” [26:56] Stress as a multiplier of aging, disease, and poor outcomes [29:20] Why stress isn't a single cause — it's layered and chronic [30:18] Anti-stress strategies: circadian rhythm, nature, and gratitude [31:49] Energy leaks to avoid: clutter, poor food, scrolling, bad boundaries [32:22] What matters most: service, contribution, and alignment [33:28] Final toolkit: breathwork, movement, nature, sleep, and gratitude [34:38] The deeper invitation: step into sovereignty and live your SuperLife     Thank You to Our Sponsors: Manna Vitality: Go to mannavitality.com/  or use code DARIN20 for 20% off your order. Bite Toothpaste: Go to trybite.com/DARIN20 or use code DARIN20 for 20% off your first order.     Find More from Darin Olien: Instagram: @darinolien Podcast: SuperLife Podcast Website: superlife.com Book: Fatal Conveniences Check out my podcast with Dr. Amy Abbington     Key Takeaway “Stress is not the enemy. It's a dashboard light — a teacher showing you where you're out of alignment. When you reframe stress, you reclaim your energy and create space for healing, safety, and the joy of living a super life.”     Bibliography (selected, peer-reviewed) Sources: Gallup Global Emotions (2024); Gallup U.S. polling (2024); APA Stress in America (2023); Natarajan et al., Lancet Digital Health (2020); Orini et al., UK Biobank (2023); Martinez et al. (2022); Leiden University (2025). Cohen S, Tyrrell DA, Smith AP. Psychological stress and susceptibility to the common cold. N Engl J Med.1991;325(9):606–612. New England Journal of Medicine Cohen S, et al. Chronic stress, glucocorticoid receptor resistance, inflammation, and disease risk. Proc Natl Acad Sci USA. 2012;109(16):5995–5999. PNAS Kiecolt-Glaser JK, et al. Slowing of wound healing by psychological stress. Lancet. 1995;346(8984):1194–1196. The Lancet Kiecolt-Glaser JK, et al. Hostile marital interactions, proinflammatory cytokine production, and wound healing.Arch Gen Psychiatry. 2005;62(12):1377–1384. JAMA Network Tawakol A, et al. Relation between resting amygdalar activity and cardiovascular events. Lancet.2017;389(10071):834–845. The Lancet Epel ES, et al. Accelerated telomere shortening in response to life stress. Proc Natl Acad Sci USA.2004;101(49):17312–17315. PNAS McEwen BS, Stellar E. Stress and the individual: mechanisms leading to disease. Arch Intern Med.1993;153(18):2093–2101. PubMed McEwen BS, Wingfield JC. Allostasis and allostatic load. Ann N Y Acad Sci. 1998;840:33–44. PubMed Felitti VJ, et al. Relationship of childhood abuse and household dysfunction to many leading causes of death in adults (ACE Study). Am J Prev Med. 1998;14(4):245–258. AJP Mon Online Edmondson D, et al. PTSD and cardiovascular disease. Ann Behav Med. 2017;51(3):316–327. PMC Afari N, et al. Psychological trauma and functional somatic syndromes: a systematic review and meta-analysis.Psychosom Med. 2014;76(1):2–11. PMC Goyal M, et al. Meditation programs for psychological stress and well-being: a systematic review and meta-analysis. JAMA Intern Med. 2014;174(3):357–368. PMC Qiu Q, et al. Forest therapy: effects on blood pressure and salivary cortisol—a meta-analysis. Int J Environ Res Public Health. 2022;20(1):458. PMC Laukkanen T, et al. Sauna bathing and reduced fatal CVD and all-cause mortality. JAMA Intern Med.2015;175(4):542–548. JAMA Network Zureigat H, et al. Physical activity lowers CVD risk by reducing stress-related neural activity. J Am Coll Cardiol.2024;83(16):1532–1546. PMC Holt-Lunstad J, Smith TB, Layton JB. Social relationships and mortality risk: a meta-analytic review. PLoS Med.2010;7(7):e1000316. PMC Chen Y-R, Hung K-W. EMDR for PTSD: meta-analysis of RCTs. PLoS One. 2014;9(8):e103676. PLOS Hoppen TH, et al. Network/pairwise meta-analysis of PTSD psychotherapies—TF-CBT highest efficacy overall.Psychol Med. 2023;53(14):6360–6374. PubMed van der Kolk BA, et al. Yoga as an adjunctive treatment for PTSD: RCT. J Clin Psychiatry. 2014;75(6):e559–e565. PubMed Kelly U, et al. Trauma-center trauma-sensitive yoga vs CPT in women veterans: RCT. JAMA Netw Open.2023;6(11):e2342214. JAMA Network Bentley TGK, et al. Breathing practices for stress and anxiety reduction: components that matter. Behav Sci (Basel). 2023;13(9):756. 

The Government's 10-year plan for the NHS (‘Fit for the future') has a dedicated section on prevention, including a ‘moonshot' to end the obesity epidemic. But what is the role of GP in the prevention of cardiovascular disease (CVD)?In this episode of the Clinical Update podcast, the MIMS Learning editors explore NICE recommendations for combination therapy to help patients achieve lipid targets for secondary prevention, the promotion of SGLT2 inhibitors to first-line options for both heart failure and type 2 diabetes, and the differences between UK and international guidelines on hypertension. Additionally, given obesity is a huge risk factor for CVD, the editors review how the management of obesity must encompass more than just GLP-1 medications.Educational objectivesAfter listening to this podcast, healthcare professionals should be better able to: Outline the prevention steps proposed in the NHS 10-year planDiscuss additional therapeutic options for achieving lipid targetsReview revised recommendations for heart failure and type 2 diabetesUnderstand the differences between UK and international hypertension targetsYou can access the website version of this podcast, along with a list of key learning points, on MIMS Learning - and make notes for your appraisal. MIMS Learning offers hundreds of hours of CPD for healthcare professionals, along with a handy CPD organiser.Please note: this podcast is presented by medical editors and discusses educational content written or presented by doctors, nurses and other healthcare professionals on the MIMS Learning website and at live events.MIMS LearningSubscribe to MIMS LearningGuidance update: latest NICE guidelines on cardiovascular disease risk assessment and reductionGuidance update: NICE guidelines on hypertensionObesity in adultsPodcast: Dr Toni Hazell on weight loss injections and women's healthPodcast: stress and its effect on the heartMIMSNICE confirms first-line role of SGLT2 inhibitors in final heart failure guidanceMonitoring requirements for hyperlipidaemia treatments Hosted on Acast. See acast.com/privacy for more information.

Sigyn Therapeutics, Inc. has announced plans to initiate a multi-site clinical feasibility study evaluating its breakthrough Sigyn Therapy™ in patients with high-risk cardiovascular disease, the world's leading cause of death, according to the World Health Organization. CEO Jim Joyce told Proactive that Sigyn Therapy is a first-in-class whole-blood adsorption technology designed to be deployed on existing dialysis machines already found in hospitals and clinics worldwide. Unlike conventional approaches, the therapy is engineered to address multiple drivers of cardiovascular disease progression in a single treatment. Specific to CVD, Sigyn Therapy has been shown to reduce circulating inflammatory molecules that accelerate disease progression, while simultaneously targeting cholesterol-transporting lipoproteins that are responsible for heart attacks, strokes, and other major adverse cardiovascular events. Building on encouraging results from pre-clinical in vitro studies, the company is expanding its feasibility study protocol to include the measurement of lipoprotein reduction during therapy. This will allow investigators to quantify the dual-action benefit of Sigyn Therapy in reducing both inflammation and lipid-related risks. The upcoming feasibility study will be a critical step toward the company's long-term goal: advancing to a pivotal efficacy study required for potential regulatory clearance and commercialization. If successful, Sigyn Therapy could represent a transformative advancement in the treatment of cardiovascular disease by integrating seamlessly into existing hospital infrastructure while addressing some of the most urgent unmet needs in cardiac care. Joyce added that the company is in the process of modifying its Investigational Device Exemption (IDE) for submission to the FDA, to formally include Ldl-c and Lp(a) reduction as observational endpoints. #proactiveinvestors #sigyntherapeuticsinc #otcqb #sigy #CardiovascularDisease #Dialysis #SigynTherapeutics #MedicalDevices #BloodPurification #ClinicalTrials #Lipoproteins #StatinAlternative #EndStageRenalDisease #FDAReview

In this episode, we discuss the Scottish Cardiovascular DES designed to reduce adverse cardiovascular events by tackling population-wide risk factors like high blood pressure, raised glucose and cholesterol. Professor James McCormack suggests a greater focus on shared decision making with patients,  arguing that the common 10% risk threshold used to trigger treatment is an arbitrary figure that often fails to clearly define what the risk actually entails. He contends that most guidelines can overlook the individual. With years of experience of teaching how to explain and apply evidence, using humour, he advocates for a foundational shift toward a patient-centred model, where treatment decisions are made with patients, not for them. The conversation explores how to put this philosophy into practice. Risk calculators such as ASSIGN and QRISK should not be used as diagnostic dictators, but as educational tools to start a conversation. He is highly critical of using terms like "pre-diabetes" or "high risk," which can cause patients to vastly overestimate their danger and create unnecessary anxiety. The solution is clear communication: using visual aids and explaining absolute benefits - for instance, a statin might change a 10% risk to 7 or 8% over a decade. By moving away from rigid protocols and chasing fluctuating measurements, clinicians can reduce patient fear, build trust through shared decision-making, and ultimately rediscover a more enjoyable and effective way to practice medicine. National cardiovascular disease (CVD) prevention and risk factors toolkit GP Evidence – fantastic site for GPs interested in shared decision making and using patient decision aids, created by Dr Julian Treadwell Complete BS Medicine podcast list – includes the Contented Clinician podcast ASSIGN v2 Cardiovascular calculator PEER simplified Cardiovascular Decision Aid NICE guidance on shared decision making James McCormack YouTube videos The Surrogate Battle - is lower always better? You can subscribe to the SNUG podcast on the following platforms: SNUG podcast on Apple podcasts      SNUG podcast on Spotify Any feedback or comments are welcome via email: alex.defranco@phs.scot    www.snughealth.org.uk 

Program notes:0:53 Who needs a beta blocker after MI1:53 Those with mild reduction of ejection fraction2:53 Confined to those with 40-50% ejection fraction3:15 Revascularization in NSTEMI4:20 Composite outcome5:20 Closes gap, do FFR6:20 May not be physiologically significant6:40 Is lifelong anticoagulation needed after ablation7:41 Occurred less in those who stopped8:30 RSV, cardiac events and hospitalizations9:30 Lower hospitalization in those who got the vaccine10:30 Acute respiratory illness hospitalization11:30 Less benefit with existing CVD or immunocompromise12:15 Several RSV vaccines13:16 End

At ESC 2025, a pair of presentations highlighted the ongoing debate over cardiovascular risk reduction with semaglutide (Ozempic/Wegovy) and tirzepatide (Mounjaro/Zepbound), yielding conflicting signals that clinicians will need to interpret carefully. In this special edition episode, cohosts Diana Isaacs, PharmD, an endocrine clinical pharmacist, director of Education and Training in Diabetes Technology, and codirector of Endocrine Disorders in Pregnancy at the Cleveland Clinic, and Natalie Bellini, DNP, program director of Diabetes Technology at University Hospitals Diabetes and Metabolic Care Center, explore these studies: SURMOUNT-5 and STEER. A post hoc analysis of SURMOUNT-5 compared the 10-year predicted CV risk reduction between the 2 agents. Using the Framingham Risk Calculator in 751 patients with obesity, tirzepatide was associated with greater benefit than semaglutide. From baseline risks of ~9%, tirzepatide was projected to lower absolute 10-year CV risk by 2.4% (23% relative reduction) compared with 1.4% (13% relative reduction) for semaglutide. Investigators attributed the advantage largely to greater weight and glycemic reductions. In contrast, the STEER study, a real-world analysis of more than 21,000 patients with a mean follow-up of 8.5 months, suggested semaglutide was associated with lower rates of major adverse cardiovascular events (MACE) than tirzepatide. Semaglutide users had a 29% risk reduction in nonfatal MI, nonfatal stroke, or CV death compared with tirzepatide. Limitations included short follow-up, relatively few CV events, and the inherent confounding of observational data. Both Isaacs and Bellini emphasized that while weight and glycemic improvements with tirzepatide appear robust, CV benefits may be molecule-specific. The ongoing SURPASS-CVOT, comparing tirzepatide with dulaglutide, should provide more clarity when full data are released at EASD. In the interim, the hosts advised prescribing based on labeled indications supported by randomized outcomes data—semaglutide for CV and kidney risk reduction, tirzepatide for obesity and sleep apnea—while awaiting definitive trial results. Relevant disclosures for Isaacs include Eli Lilly and Company, Novo Nordisk, Sanofi, Abbott Diabetes Care, Dexcom, Medtronic, and others. Relevant disclosures for Bellini include Abbott Diabetes Care, MannKind, Provention Bio, and others. References: Mamas M. SURMOUNT-5: Tirzepatide compared to Semaglutide in obesity for 10-year CVD risk reduction .Presented at the European Society of Cardiology (ESC) Congress 2025. Madrid, Spain. August 29- September 1, 2025. Novo Nordisk. Novo Nordisk's Wegovy® cuts risk of heart attack, stroke or death by 57% compared to tirzepatide in real-world study of people with obesity and cardiovascular disease. Novo Nordisk. Published August 31, 2025. Accessed September 5, 2025. https://www.novonordisk.com/content/nncorp/global/en/news-and-media/news-and-ir-materials/news-details.html?id=916422

Join Dr. Philip Ovadia and Practice Manager Cherish Thompson for a compelling conversation on cardiovascular disease (CVD) and the path to restoring health and quality of life. They'll explore the importance of early diagnostics, working with a cardiothoracic surgeon, and addressing key factors like metabolic health, LDL cholesterol, and lifestyle changes. Gain valuable insights into tackling heart disease and making impactful changes to achieve long-term wellness.Send Dr. Ovadia a Text Message. (If you want a response, you must include your contact information.) Dr. Ovadia cannot respond here. To contact his team, please send an email to team@ifixhearts.com Like what you hear? Head over to IFixHearts.com/book to grab a copy of my book, Stay Off My Operating Table. Ready to go deeper? Talk to someone from my team at IFixHearts.com/talk.Stay Off My Operating Table on X: Dr. Ovadia: @iFixHearts Jack Heald: @JackHeald5 Learn more: Stay Off My Operating Table on Amazon Take Dr. Ovadia's metabolic health quiz: iFixHearts Dr. Ovadia's website: Ovadia Heart Health Jack Heald's website: CultYourBrand.com Theme Song : Rage AgainstWritten & Performed by Logan Gritton & Colin Gailey(c) 2016 Mercury Retro RecordingsAny use of this intellectual property for text and data mining or computational analysis including as training material for artificial intelligence systems is strictly prohibited without express written consent from Dr. Philip Ovadia.

Week 0 CFB with CVD

Stream this podcast to learn from experts Alexis E. Horace, PharmD, BCACP,andNimish Patel, PharmD, PhD, AAHIVP, how specialist pharmacists can overcome key barriers to care and apply best practices for optimization of antiretroviral therapy for HIV. Topics covered include: Leveraging pharmacists' expertise to advance HIV treatmentPharmacist roles in HIV care and management The current ART landscapeRegimen simplificationConsideration of patient preferences, health factors, and comorbidities for ART optimizationART management for treatment-experienced patients, including those with multidrug-resistant HIVPresenters:Alexis E. Horace, PharmD, BCACPProfessor of Pharmacy PracticeUniversity of Louisiana at Monroe College of PharmacyNew Orleans CampusCrescentCare Ambulatory Care Clinical Pharmacist, HIV SpecialtyNew Orleans, LouisianaNimish Patel, PharmD, PhD, AAHIVPProfessor of Clinical PharmacyDivision of Clinical PharmacySkaggs School of Pharmacy & Pharmaceutical SciencesUniversity of California, San DiegoLa Jolla, CaliforniaLink to full program: https://bit.ly/41agtqQGet access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.

Cardiovascular disease (CVD) kills more women each year than all types of cancer combined, yet it may be under-recognised and under-treated in women. GP Dr Suneeta Kochhar offers practical advice on how GPs can address this. Speaking to MIMS Learning medical editor Dawn Liz Powell, Dr Kochhar explains that the reasons for this include women continuing to be under-represented in clinical trials, certain symptoms presenting differently in women compared with men, and women themselves being unaware of their risk of developing CVD.Other topics discussed in the episode include how risk factors such as type 2 diabetes play a greater role in the development of CVD in women than in men and how chest pain — the most common symptom of myocardial infarction in both men and women — may be more diffuse in women. You can access the website version of this podcast, along with a list of key learning points, on MIMS Learning — and make notes for your appraisal. MIMS Learning offers hundreds of hours of CPD for healthcare professionals, along with a handy CPD organiser.Educational objectivesAfter listening to this podcast, healthcare professionals should be better able to: Discuss the prevalence of CVD in womenUnderstand how historic under-recognition has led to poorer outcomes in womenReview the differences in presentation of CVD between women and menTarget lifestyle interventions to womenPlease note: this podcast is presented by medical editors and discusses educational content written or presented by doctors, nurses and other healthcare professionals on the MIMS Learning website and at live events.MIMS LearningSubscribe to MIMS LearningChest pain - red flag symptomsCoronary artery disease in womenIschaemic heart disease: clinical reviewPodcast: causes of stable chest painMIMS‘We're perpetuating the increased risk': Addressing unequal lipid management in women with CVD. October 2024. Hosted on Acast. See acast.com/privacy for more information.

   Slam The Gavel welcomes back Amy Palacios to the podcast. Amy was last on the podcast Season 3, Episodes 146, 165 and 179; Season 4, Episodes 134, 145 and 150; Season 5, Episodes 22, 70, 73, 83, 186, 191 and 281. The last time Amy was on we discussed, "Proving The Pattern At The Federal Level."      Amy has two ex husbands being represented by the same attorney, H. Jay White. This attorney also represented Amy at the very beginning of her case years ago. How can an attorney who has represented three people not be in conflict of interest??      Discussing her open Federal Lawsuit  5.25-CV-249-FL, Amy states that most federal lawsuits get dismissed in 30 days. Amy explained that this was the first time she has gone into the state court and actually be heard and turn in evidence, however, at the end of the trial they told her to come back in two months to get a verdict.     Amy read her complaint for Declaratory Judgement to vacate all orders in Cabarrus County, NC. Her opening statement is something everyone can learn from: "Today is my complaint for the record. I am invoking my Federal Protections. The United States Constitution, American Disabilities Act and the Violence Against Women Act. Today is my Declaratory Judgement complaint to vacate all Cabarrus County orders, to void the orders under 18-CVD-3436 and void all Child Support Orders under the 22-CVD and to return to the Mecklenburg County Order 08-CVD-25890 that was done in 2015....." To Reach Amy Palacios:  dismntlingfamilycourtcorruption.comSupportshow(https://www.buymeacoffee.com/maryannpetri)Maryann Petri: dismantlingfamilycourtcorruption.comhttps://www.tiktok.com/@maryannpetriFacebook:  https://www.youtube.com/@slamthegavelpodcasthostmar5536Instagram: https://www.instagram.com/guitarpeace/Pinterest: Slam The Gavel Podcast/@guitarpeaceLinkedIn: https://www.linkedin.com/in/maryann-petri-62a46b1ab/  YouTube:  https://www.youtube.com/@slamthegavelpodcasthostmar5536  Twitter https://x.com/PetriMaryannEzlegalsuit.com   https://ko-fi.com/maryannpetrihttps://www.zazzle.com/store/slam_the_gavel/about*DISCLAIMER* The use of this information is at the viewer/user's own risk. Not financial, medical nor legal advice as the content on this podcast does not constitute legal, financial, medical or any other professional advice. Viewer/user's should consult with the relevant professionals. Reproduction, distribution, performing, publicly displaying and making a derivative of the work is explicitly prohibited without permission from content creator. Podcast is protected by owner. The content creator maintains the exclusive right and any unauthorized copyright infringement is subject to legal prosecution. Support the showSupportshow(https://www.buymeacoffee.com/maryannpetri)http://www.dismantlingfamilycourtcorruption.com/

Arzoo CVD by Jawahrat Jewellery, Nepal's first lab-grown diamond house, crafts certified fine jewellery using advanced CVD technology. Co-founded by Bipana Mitruka and Sahil Agarwal, the brand champions ethical luxury through sustainable, affordable, and bespoke designs—reshaping South Asia's jewellery market with transparency and innovation.

In the UK there are currently about 7.2 million people diagnosed with cardiovascular disease, which amounts to about 10% of the population. Dr Jonathan Slade, GP and Medical Director for NHS England North East and Yorkshire, leads a discussion around the current focus on cardiovascular disease and the very real opportunities for prevention presented within primary care. The panel includes consultant pharmacist Dr Rani Khatib, National Specialty Advisor for CVD Prevention at NHS England. For more information on CVD prevention visit https://www.england.nhs.uk/ourwork/clinical-policy/cvd/prevention-recovery/ For more detail on CVD Prevent visit https://www.england.nhs.uk/ourwork/clinical-policy/cvd/cvdprevent/ A full transcript of this episode is available on our website - https://www.england.nhs.uk/long-read/podcast-cracking-down-on-cardiovascular-disease/

How to lose weight and achieve ultimate fitness with a carnivore diet. Personal trainer, nutrition coach, and podcast host Casey Ruff shares his top tips Burn Fat, Boost Energy, and Optimize Health. 2:00 Low-carb podcasting3:00 Peter Ballerstedt https://www.youtube.com/watch?v=6EBxUBhdwPE&t=203s4:00 Jessica Apple, Food Revolution4:30 Low carb stories5:00 Casey's carnivore diet approach6:00 Dr Anthony Chaffee's carnivore rules: https://www.youtube.com/watch?v=Xm0l8V-T5f07:00 Why Casey moved from low-cal to a low-carb approach8:00 Anxiety improvements on carnivore diet10:00 Dr Anthony Chafee: https://youtu.be/d3iXJAJaZp8?si=l9W_Na8_KPkc8W_t11:00 Dr Shawn Baker: https://youtu.be/v9KUzBjKkV4?si=npedset_jRUimZ-e12:00 The best carnivore diet book 13:00 Is carnivore safe for CVD? we dont know for sure…14:00 Dr Chaffee vs Dr Shawn Baker approaches14:30 Mental health improvements on a carnivore diet13:00 Keto calm - cravings and anxiety free from the carnivore diet18:00 Ketovore for bipolar with Jan Ellison Baszucki: https://youtu.be/ZSeicFTg-lE?si=k0spPePOiaJVAIjm 19:00 Successful podcasting tips20:00 Metabolic psychiatry, with Dr Chris Palmer and Dr Georgia Ede 20:30 Baszucki Group funding research and Metabolic Mind22:00 Anorexia and keto diet 25:00 Casey's top podcast guests27:00 Nina Teicholz: https://youtu.be/TKXDNfimEbU?si=QRK02y99JPbXNUq630:00 Tim Noakes, Aseem Malhotra, David Unwin https://youtu.be/wvieX6y2PaE?si=qpbjH6zaW-n_Zk_d31:00 Meet Casey's wife, Bethany35:00 Casey's worst year yet39:00 Casey's client incredible wins44:00 Trump, RFK junior, MAHA 45:00 Don't wait - take control of your health 48:00 Australasian Metabolic Health Society and LCDU https://youtu.be/y6_z8W1pKlg?si=SCL6ldVgeXiiG93o50:00 Health non-negotiables and how to make workouts effective 54:00 Living with purpose56:00 First steps how to get started on carnivore diet57:00 Red meat and women's health59:00 Boundless Body Radio Casey Ruff Personal Trainer Boundless Body Podcast: https://www.myboundlessbody.com/Nutrition support: claire@leafie.comFamily Health Lab Podcast: Health Trailblazers S2: E12Host: Claire McDonnell Liu, Nutritionist and podcast host claire@leafie.orgTech: https://bethe.ch/#/angeIMPORTANT - The content in this video is not a substitute for medical advice. Always consult with your physician regarding your health matters. Individuals' lifestyles, bodies and health histories vary. The author does not assume any liability to any party for any loss, damage, or disruption caused by the choice to implement any of the health strategies.

Episode Highlights With JessicaWhy does cardiovascular disease risk rise in menopause to match the rate of men?What happens to hormones and the heart when a woman goes through menopause?45% of women have some marker of cardiovascular diseaseHow the loss of estrogen in menopause is the tipping point1 in 3 women will die of cardiovascular disease which is more than all cancers combinedWhat to monitor and look out for starting in our 20s50% of people in the US have high blood pressure and this is a marker of metabolic diseaseHow insulin comes into play and why this marker is so importantWhat metabolic markers to start tracking to know your riskHow visceral fat comes into play and why this is importantWhat causes visceral fat to accumulate in the bodyHer take on microdosing GLP-1 medication and if you lose lean muscleResources MentionedThe Loving Diet - websiteJessica's Instagram

Experts discuss effective communication strategies to empower patients of their options, set realistic expectations, and guide them towards informed decisions. Claim CE and MOC Credits at https://bit.ly/VTEComm

PPH is terrible. PPH must be assessed quickly via the “4Ts” and acted upon in a timely manner. And listen to this: new data from the Journal of Maternal-Fetal & Neonatal Medicine (June 24, 2025 ahead of print) finds an association with PPH and adverse outcomes years later: the odds of cardiovascular disease (CVD) and thromboembolism disease are increased in patients with postpartum hemorrhage (PPH), to a magnitude of 1.76 fold. That's why these authors recommended "proactive postpartum care". That's what we're gonna talk about in this episode. Control of PPH includes bladder drainage, uterine massage, medications as appropriate, and mechanical methods of bleeding control. So… Vacuum uterine contraction works, and a balloon works. Even a simply 24 Fr foley has efficacy data in this setting as a uterine tamponade tool. But, in an attempt to have a LOW-COST, HIGHLY EFFECTIVE, and easy to use alternative to the Jada and Bakri- could we just use an intrauterine foley catheter and connect that to vacuum suction? JADA is effective but it limited based on uterine (EGA) size, or in cases of uterine anomaly. But most importantly…JADA and Bakri are expensive! Well, we now have data that this approach, using a low-cost, easy to use alternative, may be a consideration. It is FOCUS. This idea comes from one of our podcast family members, Dr. Frank Jackson- an MFM fellow- who has published his experience with this and already has a new publication on this technique (FOCUS), which was released as we were recording this very episode! Listen in for details.

In this debut episode of JACC This Week with Editor-in-Chief Dr. Harlan Krumholz, we explore groundbreaking studies and timely insights from the July 1st issue. Highlights include the impact of wildfire smoke on heart failure risk, new hemodynamic data on mechanical circulatory support in cardiogenic shock, and sobering cardiovascular mortality trends over the past 25 years. Plus, updates on aspirin use, cognitive impairment in CVD, ACC/AHA performance measures, and a leadership reflection from ACC President Dr. Christopher Kramer.

In this episode, CardioNerds Dr. Gurleen Kaur, Dr. Richard Ferraro, and Dr. Jake Roberts are joined by Cardio-Rheumatology expert, Dr. Monica Mukherjee, to discuss the role of utilizing multimodal imaging for cardiovascular disease risk stratification, monitoring, and management in patients with chronic systemic inflammation. The team delves into the contexts for utilizing advanced imaging to assess systemic inflammation with cardiac involvement, as well as the role of imaging in monitoring various specific cardiovascular complications that may develop due to inflammatory diseases. Audio editing by CardioNerds academy intern, Christiana Dangas. CardioNerds Prevention PageCardioNerds Episode PageCardioNerds AcademyCardionerds Healy Honor Roll CardioNerds Journal ClubSubscribe to The Heartbeat Newsletter!Check out CardioNerds SWAG!Become a CardioNerds Patron! Pearls - Cardiovascular Multimodality Imaging & Systemic Inflammation Systemic inflammatory diseases are associated with an elevated CVD risk that has significant implications for early detection, risk stratification, and implementation of therapeutic strategies to address these risks and disease-specific complications. As an example, patients with SLE have a 48-fold increased risk for developing ASCVD compared to the general population. They may also develop disease-specific complications, such as pericarditis, that require focused imaging approaches to detect. In addition to increasing the risk for CAD, systemic inflammatory diseases can also result in cardiac complications, including myocardial, pericardial, and valvular involvement. Assessment of these complications requires the use of different imaging techniques, with the modality and serial studies selected based on the suspected disease process involved. In most contexts, echocardiography remains the starting point for evaluating cardiac involvement in systemic inflammatory diseases and can inform the next steps in terms of diagnostic study selection for the assessment of specific cardiac processes. For example, if echocardiography is completed in an SLE patient and demonstrates potential myocardial or pericardial inflammation, the next steps in evaluation may include completing a cardiac MRI for better characterization. While no current guidelines or standards of care directly guide our selection of advanced imaging studies for screening and management of CVD in patients with systemic inflammatory diseases, our understanding of cardiac involvement in these patients continues to improve and will likely lead to future guideline development. Due to the vast heterogeneity of cardiac involvement both across and within different systemic inflammatory diseases, a personalized approach to caring for each individual patient remains central to CVD evaluation and management in these patients. For example, patients with systemic sclerosis and symptoms of shortness of breath may experience these symptoms due to a range of causes. Echocardiography can be a central guiding tool in assessing these patients for potential concerns related to pulmonary hypertension or diastolic dysfunction. Based on the initial echocardiogram, the next steps in evaluation may involve further ischemic evaluation or right heart catheterization, depending on the pathology of concern. Show notes - Cardiovascular Multimodality Imaging & Systemic Inflammation Episode notes drafted by Dr. Jake Roberts. What are the contexts in which we should consider pursuing multimodal cardiac imaging, and are there certain inflammatory disorders associated with systemic inflammation and higher associated CVD risk for which advanced imaging can help guide early intervention? Systemic inflammatory diseases are associated with elevated CVD risk, which has significant implications for early detection, risk stratification, prognostication, and implementation of therapeutic strategies to address CVD risk and complicat...

Graphite anode materials may become even more difficult to obtain from China as preliminary CVD rates are released. Listen to Two Minutes in Trade for more. 

During this episode a panel of experts discuss the patient journey through the interpretation and application of safety and efficacy data to establish and maintain protocols designed to address optimal VTE treatment pathways. Claim CE and MOC Credit at bit.ly/VTEPJ6 

How Can I Lower My Triglycerides? “Going to the doctor for your fasting lipid panel results can be an exercise in confusion. You will get numbers for your total cholesterol, LDL cholesterol (“unhealthy” cholesterol), HDL cholesterol (“healthy” cholesterol), and triglycerides. Although the major emphasis in treating abnormal lipid panel results focuses on getting LDL cholesterol below a certain level, your doctor might also make recommendations about your HDL and triglycerides.” Listen to today's episode for details, written by Thomas Campbell, MD at NutritionStudies.org  #vegan #plantbased #plantbasedbriefing #lipid #triglycerides #cholesterol #cvd #cardiovasculardisease #lipidpanel   ======================== Original post: https://nutritionstudies.org/lower-triglycerides/  ========================== Related Episodes: 861: Eat Quinoa and Lower Triglycerides? https://plantbasedbriefing.libsyn.com/861-eat-quinoa-and-lower-triglycerides-by-dr-michael-greger-at-nutritionfactsorg  Related Episodes: use search feature at https://www.plantbasedbriefing.com/episodes-search     Search for cholesterol, heart disease ========================= The T. Colin Campbell Center for Nutrition Studies was established to extend the impact of Dr. Campbell's life changing research findings. For decades, T. Colin Campbell, PhD, has been at the forefront of nutrition education and research. He is the coauthor of the bestselling book, The China Study, and his legacy, the China Project, is one of the most comprehensive studies of health and nutrition ever conducted. Their mission is to promote optimal nutrition through science-based education, advocacy, and research. By empowering individuals and health professionals, we aim to improve personal, public, and environmental health. ====================== FOLLOW THE SHOW ON: YouTube: https://www.youtube.com/@plantbasedbriefing     Spotify: https://open.spotify.com/show/2GONW0q2EDJMzqhuwuxdCF?si=2a20c247461d4ad7 Apple Podcasts: https://podcasts.apple.com/us/podcast/plant-based-briefing/id1562925866 Your podcast app of choice: https://pod.link/1562925866 Facebook: https://www.facebook.com/PlantBasedBriefing   LinkedIn: https://www.linkedin.com/company/plant-based-briefing/   Instagram: https://www.instagram.com/plantbasedbriefing/     

In 2016 the American Heart Association called for Cardiorespiratory Fitness (CRF), generally measured using VO2max, to be included as a vital sign. They said:“The underlying premise of this statement is that the addition of CRF for risk classification presents health professionals with unique opportunities to improve patient management and to encourage lifestyle-based strategies designed to reduce cardiovascular risk.”In this episode we discuss the arguments made and evidence cited in that statement, as well the update published in 2024.If you're the type to want follow up citations/further readings, here are a few that we found interesting (but you can find many more cited in the two statements linked above):People over 60 can still improve their VO2 by just as much as young people, relative to their baseline.Here's where you'll find the normative values from the Fitness Registry and the Importance of Exercise National Database (FRIEND) that we discussed.And before you ask, we also briefly address the classic "strength vs cardio" debate. Here are some studies we used to support it:Association of Resistance Exercise with Cardiovascular Disease Morbidity and Mortality (yes, we understand that CVD is probably not the right place to look for strength training benefits)Optimum dosing of resistance training for health and longevity

This week's topics include aging and diet, blood based biomarkers for dementia, ten and thirty year risk for cardiovascular disease, and global effect of cardiovascular risk factors.Program notes:1:00 Five factors and cardiovascular disease2:00 Additional life years free of CVD3:00 Irrespective of where you live3:27 Optimal dietary patterns for healthy aging4:28 Higher intake of fruits, vegetables5:28 Little bit better one or another6:28 Can actually change this6:40 Ten and thirty year CVD risk7:40 Risk at ten and thirty years disparate8:40 Increased cholesterol or blood pressure9:20 Blood based biomarkers10:20 Dementia free adults11:20 Risk low with none of the factors12:27 End

In this episode, a panel of experts discuss existing and emerging VTE (venous thromboembolism) treatment options for the complex patient, such as a patient who has been diagnosed with cancer, end stage renal disease (ESRD), chronic kidney disease (CKD), or is obese.  Claim CE and MOC Credit at https://bit.ly/VTEHBCPX

View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter's Weekly Newsletter In this "Ask Me Anything" (AMA) episode, Peter explores the complex world of supplements by introducing a practical framework for evaluating their effectiveness and relevance to individual health needs. Rather than providing a simple list of recommendations, Peter aims to equip listeners with the tools to critically assess supplements on their own. He then applies this framework to discuss research on several popular supplements, including creatine, fish oil, vitamin D, B vitamins, and ashwagandha. Additionally, he covers key factors in assessing supplement quality, helping listeners develop a deeper understanding of how to make informed decisions based on their personal health goals. If you're not a subscriber and are listening on a podcast player, you'll only be able to hear a preview of the AMA. If you're a subscriber, you can now listen to this full episode on your private RSS feed or our website at the AMA #69 show notes page. If you are not a subscriber, you can learn more about the subscriber benefits here. We discuss: Overview of episode topics [1:45]; How Peter evaluates patients' supplement regimens, and common misconceptions about supplements vs. pharmaceuticals [3:00]; A framework for evaluating supplements [6:15]; Evaluating creatine: purpose of supplementation, dosing, and mechanism of action [10:00]; Creatine: proven benefits for muscle performance, potential cognitive benefits, and why women may benefit more [15:15]; Creatine: risk vs. reward, kidney concerns, and choosing the right supplement [18:45]; Evaluating fish oil: its primary purpose as a supplement and how to track levels [20:45]; Fish oil: how omega-3s impact inflammation, heart health, and brain function, and the strengths and limitations of current research [26:30]; Fish oil: the risks of supplementation, guidance on selecting high-quality products, and how to determine whether supplementation is appropriate [37:30]; Evaluating vitamin D: understanding deficiency and optimal levels [45:15]; Vitamin D: role in bone health, immune function, potential longevity impact, and biomarker limitations [51:15]; Vitamin D: efficacy, safety, and balancing risk vs. reward [58:15]; Evaluating B vitamins: function, consequences of deficiency, and key biomarkers to assess whether supplementation is necessary [1:02:15]; B vitamins: risks for CVD and dementia associated with deficiency, and limited evidence for general population supplementation [1:07:15]; Evaluating ashwagandha: background, uses, and mechanism of action [1:15:30]; Ashwagandha: current evidence for its effects on sleep, stress, and anxiety [1:19:15]; Ashwagandha: evaluating supplement quality, safety profile, and the risk-reward balance [1:22:15]; The importance of using a structured evaluation framework to assess any supplement [1:26:30]; and More. Connect With Peter on Twitter, Instagram, Facebook and YouTube

Dana will be 54 on Mar 1st, 2025 and is 5'2 at 110 lbs.  She started IF on SEPT 5, 2023, after learning about it on a podcast focusing on Alzheimer's / dementia prevention/mitigation.  She was listening to that podcast b/c she lost both parents-in-law to this horrible disease. Within 1 week of starting IF, she remembers saying out loud to her husband, “I feel fantastic. I don't think I'll ever want to stop doing this.”  She never had a weight problem but suffered from a horrible sugar addiction and was raised on UPFs and LOVED sugar, especially chocolate, since she was 3 years old. Old.  She used sugar/chocolate and UPFs her whole life as a way to soothe, celebrate, comfort, connect, etc. and has struggled with emotional eating FOREVER.  Since she never really struggled much with her weight and didn't drink alcohol or smoke cigs, she always justified the emotional eating with, “No big deal - it's my one vice.”  However, her father died at 51 of a massive heart attack, as did his father and his brother, so CVD runs in her family.  On Easter of 2016, she had just binged her son's Easter candy. She was watching Dr Phil when she saw an episode about “SKINNY FAT” people - she had a significant epiphany and started a program called “28-day shred”, which was paleo eating and lost 10 lbs (going from 128-118), then took 1 day off and did another round losing six more lbs.  She only ate sugar in those 60 days once but was miserable and felt weak -she couldn't keep eating that way.  So she stopped and slowly started consuming too much sugar and UPFs again.  IF has helped her sugar cravings as well as a MILLION other NSV's.  Our Patreon Supporters Community -Join us!Please consider joining the Fasting Highway Patreon community. The feedback has been great for all who have joined. It has become an excellent add-on to our Patreon members' IF lifestyle, who enjoy a lot of bonus content to support them in living an IF life for as little as 0.16 cents a day For less than a cup of coffee a month, you can join and support your own health goals and meet like-minded people and get a lot of supportGraeme hosts Zoom meetings four times a month in the Northern and Southern hemispheres for members to come and get support for their IF lifestyle, which has proven very popular with our Patreon members.You will not find anywhere that provides that kind of support and accountability for just 0.16 cents a day. There are over 100 exclusive pieces of audio content for Patreon members to help you navigate your IF journey and get more accountability and support. Please go to www.patreon.com/thefastinghighway to see the benefits you get back and how to join. I strongly encourage you to do so for the price of a cup of coffee a month. Its a sound investment into your health.Graeme's best-selling book, The Fasting Highway, about his journey and how he did it, is available in paperback and Kindle at your local Amazon store. It is also available on audio at Applebooks, Kobo, Spotify, and many other audiobook platforms. Graeme can also be booked for one-on-one mentoring and coaching by going to www.thefastinghighway.com, clicking on get help, getting coaching, and booking a time. All times you see are in your local time zone.Disclaimer: Nothing in this podcast should be taken as medical advice. The opinions expressed herein are those of the host and guest only.

This week's topics include AI for mental illness, maternal death worldwide, CVD, education and income in the US, and sleep spindles and regain of consciousness.

For years, we've been conditioned to fear cholesterol—especially LDL. But the real problem isn't just LDL itself. The real issue? Inflammation. LDL becomes dangerous when it gets oxidized, triggering arterial damage and plaque buildup. This is why focusing only on total cholesterol or LDL isn't enough. If you really want to understand your true cardiovascular risk, here's what actually matters:

Oatmeal has long been considered a heart-healthy breakfast, but is it really as good for us as we think? In this episode, Jonathan and Sarah break down the great oat debate. First, they explore the different types of oats - instant, rolled, and steel-cut and how processing impacts their nutritional value. Then, they put oats to the test using continuous glucose monitors (CGMs), comparing instant to steel-cut, with and without toppings, to demonstrate how blood sugar works. Sarah also discusses wider debates around oats: Are pesticides a concern? Is oat milk as healthy as it claims? Finally, she shares the ultimate guide to choosing the healthiest oats - and for those who prefer alternatives, she's got delicious, nutrient-packed swaps to try.

THT 2025, AEDs in schools, PAD pain, wildfires and CVD, heart health in sexual minorities.

This month is heart health month and is the leading cause of death, we need to know as much as about it as we can so we can avoid it. Cardiovascular disease (CVD) can be caused by multiple factors, - all those factors that I talk about every week, - inflammation, oxidative stress, insulin resistance, and more. Even Hormones like estrogen, testosterone, and cortisol play a critical role in cardiovascular health. Yes, Preventable!

Something I've become a lot more knowledgeable about after my training as a GP, is cholesterol. It's probably the most important measurement every primary care doctor should know about, along with measures of metabolic health like weight, insulin resistance and blood pressure, but perhaps the least well understood.On today's episode we do a deep dive into all things cholesterol and cardiovascular disease with Professor Kausik Ray, Professor of Public Health and Honorary Cardiologist at Imperial College London and President of the European Atherosclerosis Society, and perhaps the most knowledgeable person I could talk to on this subject who has both research and clinical expertise in this area. We define exactly what we're referring to when we say cardiovascular disease (CVD) and atherosclerosis. What that entails and why it's important, being the leading cause of death globally. We discuss the importance of cholesterol in the body. Without cholesterol there is no life. Cholesterol is the precursor to our hormones, it forms the structural components of our cells, and most of our cells are able to create the cholesterol we require hence why there is no nutritional need to consume cholesterol.And, hopefully at the end of this episode you'll learn more about why the trifecta of high cholesterol, inflammation and damage to the arteries leads to disease, what blood measurements we should all have to calculate our risk, including apolipoprotein-B containing lipoproteins, Non-HDL and Lp(a), as well as the strategies to reduce risk with drugs and lifestyle.I've done other episodes on specific foods and dietary patterns to reduce cholesterol, but this I think is a necessary episode to give the backdrop to why this is important for everyone to know their numbers.

Case Discussion 118: Omalizumab in CVD

Join Dr. Jannine Krause as she sits down with Dr. Tracy Gapin, MD, FACS—a leading expert in men's health optimization, longevity, and peak performance. With over 25 years of experience as a board-certified urologist, Dr. Gapin shares transformative insights into how advanced diagnostics, wearable technology, and personalized health programs can unlock your full potential. Whether you're an entrepreneur, executive, or athlete striving for sustainable, measurable health improvements, this episode is packed with actionable strategies and cutting-edge science. What You'll Learn: The Testosterone Crisis: Why testosterone (T) levels in men decrease by 1% each year. The alarming connection between low T levels and cardiovascular disease (CVD). Why traditional testosterone reference ranges aren't optimal for peak performance. The best labs to assess your health deeper than conventional tests. Advanced Diagnostics for Health Optimization: The critical tests for understanding the root causes of high cholesterol. How Dr. Gapin uses tools like the Oura ring and continuous glucose monitors (CGMs) to optimize sleep and metabolic health. How heart rate variability (HRV) reveals stress effects on your body. The Science of Peak Performance: How hormones and epigenetics unlock your full potential. Strategies to manage stress, improve sleep, and sustain energy for peak performance. The power of real-time health monitoring through wearable technology. Why you can't manage what you don't measure—and how tracking health metrics leads to success. About Dr. Tracy Gapin: Dr. Gapin is the founder of the Gapin Institute, where he helps high-performing individuals achieve peak performance through cutting-edge health programs. He is the author of Male 2.0 and Codes of Longevity and a featured speaker at top events, including NBC and Dave Asprey's Biohacking Conference. Resources and Offers: Access Dr. Gapin's Peak Launch Program for comprehensive health optimization: Email: doctracy@gapininstitute.com Website: GapinInstitute.com/launch Text “HEALTH” to 26786 for exclusive access. Connect with Dr. Tracy Gapin: LinkedIn: Dr. Tracy Gapin Instagram & Twitter: @DrGapin Facebook: Dr. Tracy Gapin YouTube: Dr. Tracy Gapin

Low-dose aspirin (LDA), typically prescribed at a dosage of 81 mg daily, is primarily used during pregnancy to prevent or delay the onset of preeclampsia. However, the question of whether to continue LDA postpartum is less clear and requires careful consideration of the benefits and risks associated with its use in the postpartum period. After all, the American College of Cardiology and American Heart Association recommend that low-dose aspirin use (75 to 100 mg/d) might be considered for the primary prevention of atherosclerotic CVD among select adults ages 40 to 70 years at higher CVD risk but not at increased risk of bleeding. Meanwhile, the 2022 US Preventive Services Task Force (USPSTF) recommendation notes that the decision to initiate daily aspirin therapy for primary prevention of cardiovascular disease (CVD) should be made on a case-by-case basis for adults ages 40 to 59 with a 10% or greater 10-year CVD risk. The recommendation applies to those without signs or symptoms of clinically evident CVD who are not at an increased risk of bleeding. So, does continuation of LDA after delivery reduce the persistence of, or development of, chronic hypertension. Is that evidence-based? The answer is both YES and NO. Listen in for details.

This week we delve into preventive cardiology with noted world authority, Associate Professor of Pediatrics, Dr. Carissa M. Baker-Smith of Nemours Health. In the present era, what roles do environment and social determinants of health play in cardiovascular disease? How should practitioners take a family history and how has the family history evolved in modern times? How can clinicians be sure that they are not 'missing' factors when they are trying to screen for cardiovascular disease risk in their patients? What are a few practical changes in how we speak with patients that we can all make to improve our understanding of our patients and their families? An important conversation this week with Dr. Baker-Smith.https://doi.org/10.1007/s11883-024-01232-4

This week's topics include Medicare negotiation on drug price comparison, messaging to improve adherence to CVD medications, maternal cancer detection, and VILPA.

Today's guest is Dr. Bradley Bale, a pioneering cardiologist and co-founder of the BaleDoneen Method.In this episode, we explore Brad's fearless approach to life, the driving force behind his groundbreaking practice, and dive into why he's willing to take a few arrows in the back for what he believes in.The BaleDoneen Method is a personalized approach to preventing and managing heart attacks, strokes, and cardiovascular disease (CVD). It focuses on identifying and treating the root causes of arterial disease rather than just addressing risk factors like high blood pressure or cholesterol.ResourcesFollow your curiosity, connect, and join our ever-growing community of extraordinary minds.CariFree WebsiteCariFree on InstagramCariFree on FacebookCariFree on PinterestThe BaleDoneen Method WebsiteBeat the Heart Attack GeneThe Bezos BlueprintThe Biology of KindnessWhat's In This EpisodeBrad's motivation for taking a few arrows in the back.Why the cardiovascular status quo isn't good enough.The financial incentives of late-stage treatment and not prevention.The power of optimistic thinking.

The Filtrate:Joel TopfSwapnil HiremathWith Special Guest:Michelle Hladunewich, Nephrologist at the University of TorontoMir Melamed, Maternal-Fetal Medicine at the University of TorontoEditor Simon TopfShow NotesPriscilla Smith's letter:Dear Joel and the Freely Filtered team,I am a long-time fan of your podcast and was looking forward to hearing your recently aired discussion of the Praecis study of sflt1:PlGF use in preeclampsia. Preeclampsia and renal disease in pregnancy are areas that many nephrologists report a lack of knowledge or confidence in discussing and managing. I am a nephrologist who has been co-leading a renal pregnancy clinic in London while writing a PhD on progression of renal disease in pregnancy. I have had the immense privilege of working with experts and key opinion leaders in preeclampsia research both in the UK and internationally. As you know, preeclampsia is a serious and significant condition contributing to global maternal mortality and is also associated with future CKD and CVD risk so is both relevant and important within our professional group.Sadly, I found myself disappointed by the episode and felt it was a missed opportunity. I appreciate that you had difficulties obtaining appropriate experts to join the discussion, but perhaps it would have been better to delay production. While you all valiantly proceeded to discuss this important study, the topic is complex and there appeared to be a lack of understanding of the surrounding literature and pathogenesis of preeclampsia. Sadly, the maternal medicine expert's comments at the end of the podcast added little as she seemed determine to negate any benefit from the results despite declaring she had no experience or expertise in the use of these biomarkers.There are many people who understand the clinical aspects of preeclampsia as well as having direct experience of the use and utility of these biomarkers who would have been able to contribute much to your conversation. I look forward to future discussions of renal disease in pregnancy on your podcast and would be happy to suggest some expert panellists if you ever find yourself stuck.Kind regards,Priscilla Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsia (JCI 2003)sFlt background: Pathogenesis of Preeclampsia and Therapeutic Approaches Targeting the Placenta (PubMed)PlGF background: Perspectives on the Use of Placental Growth Factor (PlGF) in the Prediction and Diagnosis of Pre-Eclampsia: Recent Insights and Future Steps (PubMed)The PRAECIS trial (NephJC | NEJM Evidence)

Join Kate, Gary, Henry and Mark as they discuss a new therapy for dry eye syndrome, antibiotics for suspected UTI in adults with delirium, a new ACG guideline for treating H pylori, and the prevalence of knee pathology in asymptomatic adults. See below for links to the articles and other stuff: Dry eye treatment BMJ: https://www.bmj.com/content/386/bmj-2024-080474 Patient instructions: https://www.bmj.com/content/bmj/suppl/2024/09/11/bmj-2024-080474.DC1/liji080474.ww2.pdf Antibiotics for UTI in delirium: https://pubmed.ncbi.nlm.nih.gov/38895992/ ACG guideline for H. Pylori: https://pubmed.ncbi.nlm.nih.gov/28071659/ MRI of asymptomatic knees: https://pubmed.ncbi.nlm.nih.gov/32060622/ Elections and CVD: https://pmc.ncbi.nlm.nih.gov/articles/PMC9021908/

Just The Inserts isn't anonymous anymore… today we're introducing Alexandra to you, and you're getting to see her face for the first time.This is our second interview with her (first episode linked below). In this interview we go even deeper than the first time, discussing the RSV shot the CVD/flu shot mash-up, mRNA products, and a hard look at the Vitamin K product that babies get on their first day of life.As always in conversation with Alexandra, informed consent is paramount. We speak to the value of people being provided with all the information they need in order to make an informed decision, and discuss the need for that decision to be respected regardless of what that decision ends up being.Order sets/standing orders are discussed in detail, the impact of 2020 on the medical community at large, and the relationship between authority and responsibility is fully dissected.We end talking a bit more about her new book, Well Considered, a wonderful informed consent resource.This is a CAN'T MISS episode that you'll want to be sure to share.LINK TO OUR FIRST INTERVIEW WITH JUST THE INSERTS: https://open.spotify.com/episode/3zTX4nvx0Xg8H3xAHalnCU?si=jiez05NeTAuz7KODRd2ExgGUEST:Alexandra of Just The Insertshttps://www.justtheinserts.comhttps://justtheinserts.store (get her book here)https://www.instagram.com/justtheinserts?igsh=MTBhNDY3amVwNmVpNg==SPONSORS:Pure Anada:https://www.pureanada.caRowe Casa:Use code BOOMCLAP to save 20% off your first order!https://www.rowecasaorganics.com/?sca_ref=3468709./2CVRBIBV1RMDY Collective Homeopathy:BOOMCLAP to save 10% as you try out homeopathy for yourself!https://rmdycollective.com/boomclappodcastFIND US / SUPPORT THE PODCAST: https:theboomclappodcast.square.sitewww.instagram.com/boomclappodcastwww.instagram.com/cecily.dickey www.instagram.com/ritarogersco

View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter's Weekly Newsletter Isaac "Zak" Kohane, a pioneering physician-scientist and chair of the Department of Biomedical Informatics at Harvard Medical School, has authored numerous papers and influential books on artificial intelligence (AI), including The AI Revolution in Medicine: GPT-4 and Beyond. In this episode, Zak explores the evolution of AI, from its early iterations to the current third generation, illuminating how it is transforming medicine today and unlocking astonishing possibilities for the future. He shares insights from his unconventional journey and early interactions with GPT-4, highlighting significant AI advancements in image-based medical specialties, early disease diagnosis, and the potential for autonomous robotic surgery. He also delves into the ethical concerns and regulatory challenges of AI, its potential to augment clinicians, and the broader implications of AI achieving human-like creativity and expertise. We discuss: Zak's unconventional journey to becoming a pioneering physician-scientist, and his early interactions with GPT-4 [2:15]; The evolution of AI from the earliest versions to today's neural networks, and the shifting definitions of intelligence over time [8:00]; How vast data sets, advanced neural networks, and powerful GPU technology have driven AI from its early limitations to achieving remarkable successes in medicine and other fields [19:00]; An AI breakthrough in medicine: the ability to accurately recognize retinopathy [29:00]; Third generation AI: how improvements in natural language processing significantly advanced AI capabilities [32:00]; AI concerns and regulation: misuse by individuals, military applications, displacement of jobs, and potential existential concerns [37:30]; How AI is enhancing image-based medical specialties like radiology [49:15]; The use of AI by patients and doctors [55:45]; The potential for AI to augment clinicians and address physician shortages [1:02:45]; The potential for AI to revolutionize early diagnosis and prediction of diseases: Alzheimer's disease, CVD, autism, and more [1:08:00]; The future of AI in healthcare: integration of patient data, improved diagnostics, and the challenges of data accessibility and regulatory compliance [1:17:00]; The future of autonomous robotic surgery [1:25:00]; AI and the future of mental health care [1:31:30]; How AI may transform and disrupt the medical industry: new business models and potential resistance from established medical institutions [1:34:45]; Potential positive and negative impacts of AI outside of medicine over the next decade [1:38:30]; The implications of AI achieving a level of creativity and expertise comparable to exceptional human talents [1:42:00]; Digital immortality and legacy: the potential to emulate an individual's personality and responses and the ethical questions surrounding it [1:45:45]; Parting thoughts [1:50:15]; and More. Connect With Peter on Twitter, Instagram, Facebook and YouTube

My omega-3 guide on concerns like a-fib, dosage, supplement quality, oxidation, and more Discover my premium podcast, The Aliquot Join over 300,000 people and sign up for my newsletter Become a FoundMyFitness premium member to get access to exclusive episodes, emails, live Q+A's with Rhonda and more In this special solo episode of FoundMyFitness, we're taking a deep dive into alcohol. We'll explore the science, misconceptions, controversies, and health effects of this widely used drug. I believe that a nuanced, scientific discussion on alcohol is the best way to provide you with the information you need to make an informed decision about alcohol use. Timestamps (00:00) Introduction (08:03) What does it mean to "have a drink"? (09:39) Drinking frequency definitions (12:39) How alcohol is metabolized (18:25) Can alcoholism be inherited? (19:41) How food affects alcohol metabolism (21:40) Does age affect alcohol metabolism? (22:29) How alcohol affects nutrient absorption (27:04) How alcohol affects gut health (28:57) Alcohol elevates circulating LPS levels (31:51) Gut health & alcohol use disorders (36:30) Sick quitter & healthy user biases (39:38) How alcohol impacts the brain (43:34) Alcohol's effects on anxiety (49:56) Alcohol facilitates thiamine deficiency (51:39) Alcohol promotes brain inflammation (52:56) Dementia & Alzheimer's disease risk  (1:06:50) Is resveratrol in red wine beneficial? (1:11:28) How alcohol impacts sleep (1:19:47) Mitigating alcohol's impact on sleep  (1:22:13) Hangover symptoms & causes (1:26:33) How congeners affect hangover severity (1:27:58) Treating hangovers with fruit (1:30:40) Zinc, vitamin B3, & hangovers (1:31:41) Managing hangovers with NSAIDs (1:32:22) "Hair of the dog” for hangovers (1:32:40) Liposomal glutathione, NAC, & hangovers (1:35:56) Does ZBiotics prevent hangovers? (1:38:18) Dihydromyricetin (DHM) for hangovers (1:39:15) Exercise & sauna for treating hangovers (1:40:21) Alcohol's effect on mortality risk  (1:44:28) Alcohol consumption in Blue Zones (1:49:07) Does alcohol increase cancer risk? (2:00:43) Can quitting alcohol lower cancer risk? (2:09:46) Alcohol & cardiovascular disease (CVD) (2:23:24) Alcohol and type 2 diabetes risk (2:28:28) Alcohol's impact on your waistline (2:31:33) Why alcohol facilitates weight gain (2:34:06) How alcohol impacts reproductive health (2:44:31) Preconception alcohol risks (2:47:12) How alcohol affects testosterone in men (2:48:55) Pre-pregnancy alcohol consumption risks (2:53:17) Is red wine the healthiest option? (2:57:47) Alcohol & post-exercise recovery (3:01:34) Does alcohol "blunt your gains"? (3:04:11) The BEER-HIIT study (3:05:03) Can exercise lessen alcohol cravings? (3:12:57) Alcohol damage control tactics Show notes are available by clicking here Watch this episode on YouTube

View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter's Weekly Newsletter In this “Ask Me Anything” (AMA) episode, Peter provides insights on a broad range of important topics. He delves into the prevention of cognitive decline, the link between cardiovascular disease and Alzheimer's disease, and methods to lower blood glucose, insulin, and apoB. He also addresses nutrition-related queries, exploring the impact of dietary habits on weight loss and longevity, how a person can identify the best diet for themselves, and common nutrition myths. Additional discussions include optimal blood pressure, daily step goals, the benefits of standing versus sitting desks, and much more. If you're not a subscriber and are listening on a podcast player, you'll only be able to hear a preview of the AMA. If you're a subscriber, you can now listen to this full episode on your private RSS feed or our website at the AMA #60 show notes page. If you are not a subscriber, you can learn more about the subscriber benefits here. We discuss: Overview of topics and episode format [1:40]; Preventing cognitive decline [5:00]; How to lower blood glucose and insulin [13:30]; The relationship between lipids, CVD, and Alzheimer's disease, and whether statins can increase the risk of neurodegenerative disorders and AD [23:15]; Reducing apoB levels through exercise and diet [31:45]; Pharmacological options for lowering apoB [38:00]; How nutrition impacts longevity via metabolic health, muscle mass, BMD and more [40:15]; How can someone determine the best diet for themselves? [43:45]; Nutrition myth: All weight loss is good [46:45]; Nutrition myth: Metabolic rates are dramatically different among individuals based on genetics [49:00]; Nutrition myth: Losing weight after a brief period of overeating is impossible [53:45]; Nutrition myth: GLP-1 agonists are a replacement for a healthy lifestyle [57:45]; Nutrition myth: There is a single best diet for weight loss [1:03:00]; Nutrition oversimplification: All calories are created equal [1:05:45]; Daily step goals [1:06:45]; The benefits of standing versus sitting throughout the day [1:10:45]; How to identify the most impactful and easiest-to-implement ways to improve your health [1:12:30]; The critical importance of emotional health [1:14:30]; Why supplements should be considered as supportive aids rather than primary solutions in one's strategy to improve longevity [1:18:00]; Strategies for reducing high blood pressure [1:20:45]; Peter's biggest frustrations with "mainstream health advice" [1:28:00]; Peter's chaotic, yet cherished, morning routine [1:31:00]; and More. Connect With Peter on Twitter, Instagram, Facebook and YouTube