Podcasts about muthukumar

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  • 42EPISODES
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Best podcasts about muthukumar

Latest podcast episodes about muthukumar

GI Insights
Advances in IBD Care: Monitoring with Wearable Sensors

GI Insights

Play Episode Listen Later Feb 6, 2025


Guest: Shalini Prasad, PhD Guest: Sriram Muthukumar, PhD Host: Charles Turck, PharmD, BCPS, BCCCP With the constant ups and downs of inflammatory bowel disease (IBD), consistent monitoring can help provide patient-centric care. Dr. Shalini Prasad and Dr. Sriram Muthukumar, co-founders of EnLiSense, join GI Insights to discuss the wearable device they developed to track inflammation markers in IBD patients. Dr. Prasad is the Head of the Department of Bioengineering at the University of Texas at Dallas, and Dr. Muthukumar is the CEO of EnLiSense.

Conference Coverage
Advances in IBD Care: Monitoring with Wearable Sensors

Conference Coverage

Play Episode Listen Later Feb 6, 2025


Guest: Shalini Prasad, PhD Guest: Sriram Muthukumar, PhD Host: Charles Turck, PharmD, BCPS, BCCCP With the constant ups and downs of inflammatory bowel disease (IBD), consistent monitoring can help provide patient-centric care. Dr. Shalini Prasad and Dr. Sriram Muthukumar, co-founders of EnLiSense, join GI Insights to discuss the wearable device they developed to track inflammation markers in IBD patients. Dr. Prasad is the Head of the Department of Bioengineering at the University of Texas at Dallas, and Dr. Muthukumar is the CEO of EnLiSense.

In Depth
Inside marketing at Stripe, OpenAI and Retool | Krithika Muthukumar (VP of Marketing at OpenAI, ex-Stripe, Retool, Dropbox, Google)

In Depth

Play Episode Listen Later Aug 1, 2024 68:04


Krithika Muthukumar is a marketing veteran. She is currently the VP of Marketing at OpenAI where she was the first marketing hire. Before that, she was Head of Marketing at Retool. Her longest tenure was at Stripe where she was hired as the first marketer and scaled with the company over nine years, from a 60-person team to 7500+. She began her career in Product Marketing at Google and Dropbox. – In today's episode, we discuss: Marketing lessons from OpenAI, Stripe, and Retool The 3 pillars of Stripe's approach to brand How to manage resource allocation as a marketer Adapting marketing strategy to different business models Advice for early marketing hires – Referenced: Coca-Cola AI-generated wish card campaign: https://theprint.in/ani-press-releases/coca-cola-ignites-diwali-celebrations-with-unique-personalized-ai-generated-wish-cards/1840093/ Cristina Cordova: https://www.linkedin.com/in/cristinajcordova/ Gong: https://www.gong.io/ Greg Brockman: https://www.linkedin.com/in/thegdb/ Kenzo Fong: https://www.linkedin.com/in/kenzofong/ Retool: https://retool.com/ Stripe's “Capture the Flag” campaign: https://techcrunch.com/2012/08/22/stripes-capture-the-flag-2-0-a-hands-on-contest-for-app-developers-to-test-their-security-know-how/ Stripe Press: https://press.stripe.com/ Stripe Sigma: https://stripe.com/us/sigma Tanya Khakbaz: https://www.linkedin.com/in/tanya-khakbaz-a725732/ – Where to find Krithika Muthukumar: LinkedIn: https://www.linkedin.com/in/krithix/ Twitter/X: https://x.com/krithix – Where to find Brett Berson: LinkedIn: https://www.linkedin.com/in/brett-berson-9986094/ Twitter/X: https://twitter.com/brettberson – Timestamps: (00:00) Intro (02:43) Getting involved in Stripe (05:37) Evaluating success in product marketing (06:35) The 3 pillars of Stripe's approach to brand (12:10) Managing resource allocation as Stripe grew (17:22) How Stripe scaled taste (21:30) Were Stripe reviews micromanaging? (24:16) Marketing under founders with strong marketing skills (26:44) Advice for early marketing hires (31:52) Marketing at Retool vs Stripe (33:59) Marketing to mid-market vs SMB vs enterprise (37:02) Marketing programs that had an outsized impact (39:59) Marketing horizontal vs vertical products (43:20) Lessons from OpenAI (52:22) Inside OpenAI's recent website relaunch (55:57) How OpenAI's marketers use OpenAI tooling (59:53) When to start hiring marketers (61:34) How to screen early marketing hires (66:39) The biggest influences on Krithika's career (67:52) Outro

Burn Youth
How to run a Jesus Club // Jovaan Muthukumar & Hamish Peterson

Burn Youth

Play Episode Listen Later Jul 29, 2024 37:41


Reach your school with the gospel of Jesus Christ.

Rj Toshila
The essence of ⁠Na. Muthukumar⁠ in our lives will never fade

Rj Toshila

Play Episode Listen Later Jul 6, 2024 2:05


Here's my take on Fatherhood

Health Literacy Out Loud Podcast
Helping Patients Prepare Lists of Questions to Ask at Medical Appointments (HLOL #243)

Health Literacy Out Loud Podcast

Play Episode Listen Later Jan 1, 2024 26:13


Akila Muthukumar graduated summa cum laude from Harvard College with a major in human developmental and regenerative biology and a minor in English. Muthukumar helped establish and lead a question-listing service at Massachusetts General Hospital in Boston. She also has done a lot of writing, including for the health and medicine website, STAT News. She […] The post Helping Patients Prepare Lists of Questions to Ask at Medical Appointments (HLOL #243) appeared first on Health Literacy Out Loud Podcast.

Seki Bookmark
Anilaadum Moontril - Na Muthukumar | Akka | Tamil Articles | Tamil Podcast | Seki Bookmark

Seki Bookmark

Play Episode Listen Later Dec 22, 2023 8:26


Anilaadum Moontril - Na Muthukumar | Akka | Tamil Articles | Tamil Podcast | Seki Bookmark

The Scene From Above Podcast
S14E1: European Union Deforestation free Regulation (EUDR) with Dr.Vivian Ribeiro

The Scene From Above Podcast

Play Episode Listen Later Nov 27, 2023 30:27


In the first episode of Season 14, we talk to Dr. Vivian Ribeiro about the challenges and opportunities of the new European Union Deforestation free Regulation (EUDR) in the Earth Observation Sector. Dr. Vivian Ribeiro is a senior data scientist at the Stockholm Environment Institute and currently leads the spatial intelligence team in the Trase - Intelligence for Sustainable Trade initiative. She is also the co-founder and technical coordinator of the Do Pasto ao Prato app, a collaborative initiative aimed at increasing transparency in the Brazilian meat industry. Vivian holds degrees in biology from the University of Goias and masters and Ph.D. in ecology from the University of Brasilia Twitter: https://twitter.com/vivihrbr LinkedIn: https://www.linkedin.com/in/vivian-ribeiro-276357a8/   Shownotes: Do Pasto ao Prato: https://www.dopastoaoprato.com.br/ Trase: www.trase.earth   Season 14 of Scene from Above is brought to you by Geoawesomeness. Be sure to check out the EO Hub article by Muthukumar featured on S14E1: https://bit.ly/EUDREarthObservation   News Correspondent:  Rafaela Tiengo: https://twitter.com/RafaelaTiengo_ Subscribe to Rafaela's Newsletter! https://rafaelatiengo.substack.com/   Hosts, co-host and organizers: Dr. Flávia de Souza Mendes: https://www.linkedin.com/in/fl%C3%A1via-de-souza-mendes-phd-1456362b/ Dr. Yhasmin Mendes de Moura https://www.linkedin.com/in/yhasmoura/ Dr. Michelle Picoli: https://www.linkedin.com/in/michelle-picoli-234709a2/   Editor and translation: Dr. Flávia de Souza Mendes   Disclaimer: The views and opinions expressed in this podcast are those of the speakers and do not necessarily reflect the views or positions of any entities they represent.  

Chennaikaaran Tamil Podcast
Episode 60 - Thoughts about Ayali

Chennaikaaran Tamil Podcast

Play Episode Listen Later Mar 6, 2023 20:22


Hello everyone, I hope all are well. In this 60th Episode of the Podcast, I share my thoughts on the recently released Zee5 Tamil Web Series Ayali directed by Muthukumar. The show is set up in the early 1990s. The show focuses on a girl and how she tries to defy the patriarchal norms of her village. If you like to support my work, You can buy me a Coffee using this link:https://www.buymeacoffee.com/Chennaikaaran See you soon in the next episode. Ciao :) --- Send in a voice message: https://podcasters.spotify.com/pod/show/chennaikaaran-podcast/message

coffee muthukumar
Youturn Media
காலுக்கிடையில் என்னடா கெளரவம் ? | Iyan Karthikeyan | Ayali Director Muthukumar | Youturn

Youturn Media

Play Episode Listen Later Feb 14, 2023 54:46


In this episode, Iyan Karthikeyan and Ayali director Muthu Kumar talked about the film "Ayali," women's empowerment, and challenges that women deal with in society. Support our fact check initiatives - https://youturn.in/support-us For fact check and other special articles, visit our website at https://youturn.in We are also available in English at https://en.youturn.in Android App - http://bit.ly/3obVUnA Allow us to reach you through Social Media: Twitter - http://bit.ly/2Y4Vox2 Facebook - http://bit.ly/3iFvp8N Instagram - http://bit.ly/2MjqEpi #Youturn #TamilFacts #Ayali #IyanKarthikeyan

Tamil Short Stories - Under the tree
Oru Roobai Rahasyam by Na.Muthukumar

Tamil Short Stories - Under the tree

Play Episode Listen Later Dec 7, 2022 8:24


"Under the Tree" is an initiative to re - live the child hood and our lives by relating to stories by great writers of yesteryears. The objective is to rekindle the interest of reading and showcase the Indian authors work which give rebirth to the tradition, culture. Spiritual series that is rich in Indian ethos along with Management aspects increase positivity which is much needed always..

Chewing the Fat with Jeff Fisher
Ep 930 | Oh It's Going To Happen…

Chewing the Fat with Jeff Fisher

Play Episode Listen Later Aug 8, 2022 43:51


Nothing Sacred anymore…Warning! Fake musicians beggin for cash… What happens to the money?... Joker Folie a deux with Gaga… Nicole and AMC staying together… Top Gun overtakes Titanic… Ben and Jen branding… Who Died Today: Roger E Mosley 83 / Clu Gulager 93 / Muthukumar?/ Kim and Pete nine months… Anne Heche in car crash… Spacey to pay 31 million… Alex 45 million more… Cobra still missing… Huntin snakes in Florida… Email joke of the day…  Learn more about your ad choices. Visit megaphone.fm/adchoices

amc muthukumar
Pattukkaaran
Pattukkaaran - Iniya Pirandhanaal Nalvazthukal Muthukumar

Pattukkaaran

Play Episode Listen Later Jul 12, 2022 40:54


First of all, thank you for the overwhelming response guys. It's an emotional episode, reading all the lovely letters made me feel full. Iniya Pirandhanaal Nalvazthukal, Muthukumar na ❤️ --- Support this podcast: https://anchor.fm/pattukkaaran/support

muthukumar
KADHAIYAADAL
Pookal pookum tharunam S02 E05

KADHAIYAADAL

Play Episode Listen Later Jun 16, 2022 8:24


Pookal pookkum tharunam , Lyrics by poet Na.Muthukumar ❤️

lyrics muthukumar
The Official SaaStr Podcast: SaaS | Founders | Investors
SaaStr 544: People, Process and Product: A Product Leader's First 90 Days with Notion CPO Madhu Muthukumar

The Official SaaStr Podcast: SaaS | Founders | Investors

Play Episode Listen Later Apr 6, 2022 28:55


Being a product leader is different at every company, and learning to lead at every company can widely vary. After leading product teams at Twitter, Oculus, and Robinhood, and working with companies of all sizes at McKinsey, TechStars, and now as an investor — here's exactly how Madhu approaches his first 90 days on the job as CPO at Notion, step-by-step. He'll walk through foundations, learnings, and challenges, pulling insights and experiences from the top product leaders in software. This episode is an abbreviated version of Madhu's session at SaaStr Build. You can see the full video here: https://youtu.be/kxgox905lho Want to join the SaaStr community? We're the

Books & More
Episode 42 : Aniladum Mundril - Na.Muthukumar

Books & More

Play Episode Listen Later Apr 4, 2022 10:42


A book which shows the importance of various relationships in our life by Na.Muthukumar

muthukumar
MoviePrizm
'Mahaan' - Tamil Movie Review

MoviePrizm

Play Episode Listen Later Feb 15, 2022 4:20


On the day he turns 40, when his wife and son is out for a spiritual trip, Mahaan a strict Gandian decides to enjoy his life for a single day by commiting all the Sins around him, but that changes the course of his life, What happens next? - Read our review and catch up with the movie on Amazon Prime. Starring: Vikram, Dhruv Vikram, Simran, Bobby Simha, Sananth, Muthukumar

808 Podcast
#225 Krupesh Muthukumar - RevenueHero

808 Podcast

Play Episode Listen Later Feb 3, 2022 8:06


Krupesh Muthukumar the Co-Founder of RevenueHero shares how to have your revenue teams close more deals by prioritizing prospects based on usage data. Get more info at https://www.RevenueHero.io/

co founders muthukumar
Maharani Talks
E48: Raksha Muthukumar - Tech unions keep Big Tech in check

Maharani Talks

Play Episode Listen Later Feb 3, 2022 42:11


Tech unions are considered a rarity in Silicon Valley. So, when Google employees announced the Alphabet Workers Union (AWU), named after Google's parent company, it ended up becoming a catalyst for white collar workers to stand up against injustices in the workplace.  Raksha Muthukumar was one of the union's earliest members and helped in its formation. A GeorgiaTech graduate, during her work stint with Google, she saw the growing discontent among employees over Google's sexual discrimination practices, which led to the 2018 global walk out by Google employees, and over its ethical use of technology, which saw the forced exit of Dr. Timnit Gebru, a respected figure in ethical practice of AI. In October last year, Raksha was named as one of the 18 tech activists to watch out for by Business Insider, along with the likes of Frances Haugen who exposed Facebook's algorithm decisions. The union itself has been extensively covered by numerous publications such as Forbes, TechCrunch, and The New York Times. So what did it take to make it happen? You can get in touch with Raksha at https://raksha.gay/ You can reach me at maharanitalks@gmail.com or on Instagram https://www.instagram.com/maharanitalks/ MUSIC: Lights by Sappheiros https://soundcloud.com/sappheirosmusic

Pattukkaaran
Pattukkaaran - Na Muthukumar'um Yuvan'um! feat., Divakar Revath Kumar

Pattukkaaran

Play Episode Listen Later Dec 24, 2021 72:49


If you know Pattukkaaran, you'll definitely know how much I value, love Yuvan & Na Muthukumar! This episode, I have Divakar; my friend with whom I discuss and share our mutual love, respect and admiration towards Yuvan, Muthukumar & the COMBO :) I hope you guys enjoy this episode! --- Support this podcast: https://anchor.fm/pattukkaaran/support

kumar muthukumar yuvan
Books & More
Episode 27 : Bala Kaandam - Na.Muthukumar

Books & More

Play Episode Listen Later Dec 20, 2021 11:02


A book about his childhood memories

bala muthukumar
Books & More
Episode 14 : Kulanthaigal vaalum veedu

Books & More

Play Episode Listen Later Sep 20, 2021 4:23


Haikoo collections of Na.Muthukumar

muthukumar
Soulcast
EP 7 - Book Conversations (Part 2)| Ft. Divya Muthukumar .

Soulcast

Play Episode Listen Later Aug 13, 2021 24:04


HI! In this episode, we talk about books! or rather we geek out over Dan Brown, tinkle comics ( THE OG ), and Percy Jackson (obviously while complaining about how bad the movie is ) and answer some Q&As in segment 2 about reading and how to start reading more (is there a part 2 ? DUN DUN DUN ) I haven't read in a while so I had to bring in the expert, a close friend of mine Divya, who loves reading and that's all we need. apart from reading, Divya loves painting and creating music check her content out at IG: https://www.instagram.com/heydivyeah/ please remember to hit the follow button on this podcast to get regular updates to your device when we upload, it helps us understand what content you like Videos are uploaded every Friday at 6 PM (IST) Get in touch! SOCIALS Instagram :- https://www.instagram.com/soulcastpod Facebook:- https://www.facebook.com/SoulcastPodcast STREAMING PLATFORMS Anchor :- https://anchor.fm/soulcastpodcast Spotify:- https://open.spotify.com/show/7iY1aNe Apple podcast:- https://podcasts.apple.com/us/podcast Amazon music/audible:- https://music.amazon.in/podcasts/a73533cc-00cc-47dc-9962-ab092baee635/SOULCAST Website :- https://soulcast829291033.wordpress.com/ background music used in the video is:- Artist: Cheel | Track: Anywhen You Say https://www.youtube.com/watch?v=Vbs__YOBv3U thank you cheel!

Aalapirandhaval-Tamil PODCAST
ஒரு தகப்பனின் கடிதம்|அணிலாடும் முன்றில்|நா.முத்துகுமார் கவிதை

Aalapirandhaval-Tamil PODCAST

Play Episode Listen Later Aug 8, 2021 3:11


A Letter wrote by Na.Muthukumar to his Son --- Send in a voice message: https://anchor.fm/aala-pirandhaval/message

letter muthukumar
Soulcast
EP 7 - Book Conversations | Ft. Divya Muthukumar .

Soulcast

Play Episode Listen Later Jul 30, 2021 19:52


HI! In this episode, we talk about books! or rather we geek out over Dan Brown, tinkle comics ( THE OG ), and Percy Jackson (obviously while complaining about how bad the movie is ) and answer some Q&As in segment 2 about reading and how to start reading more (is there a part 2 ? DUN DUN DUN ) I haven't read in a while so I had to bring in the expert, a close friend of mine Divya, who loves reading and that's all we need. apart from reading, Divya loves painting and creating music check her content out at IG: https://www.instagram.com/heydivyeah/ please remember to hit the follow button on this podcast to get regular updates to your device when we upload, it helps us understand what content you like Videos are uploaded every Friday at 6 PM (IST) Get in touch! SOCIALS Instagram :- https://www.instagram.com/soulcastpod Facebook:- https://www.facebook.com/SoulcastPodcast STREAMING PLATFORMS Anchor :- https://anchor.fm/soulcastpodcast Spotify:- https://open.spotify.com/show/7iY1aNe Apple podcast:- https://podcasts.apple.com/us/podcast Amazon music/audible:- https://music.amazon.in/podcasts/a73533cc-00cc-47dc-9962-ab092baee635/SOULCAST Website :- https://soulcast829291033.wordpress.com/ background music used in the video is:- Artist: Cheel | Track: Anywhen You Say https://www.youtube.com/watch?v=Vbs__YOBv3U thank you cheel!

IMBeeDi Tamil Podcast
E 8 : Na.Muthukumar is Inevitable | A Tribute

IMBeeDi Tamil Podcast

Play Episode Listen Later Jul 12, 2021 33:50


Celebrating the magical lyrics and the man behind those words❤️ #HBDNaMu

Bench Talkies
Na Muthukumar Birthday Special

Bench Talkies

Play Episode Listen Later Jul 12, 2021 10:33


Priya's Talk

Books & More
Episode 4 : Ninaivo oru paravai - Na.Muthukumar

Books & More

Play Episode Listen Later Jul 12, 2021 8:45


A book by national award winner Na.Muthukumar about his various life memories

muthukumar
Pattukkaaran
Pattukkaaran - En Muthukumar

Pattukkaaran

Play Episode Listen Later Jul 12, 2021 19:01


July 12th! It's my Na Muthukumar's birthday... :) Happy birthday sir. I'm sure you are around. This episode, is all about Me and Muthukumar. Nothing else :) --- Support this podcast: https://anchor.fm/pattukkaaran/support

muthukumar
The Habit Coach with Ashdin Doctor
Ep: 496: The Habit Coach Hot Seat - Malavika MuthuKumar

The Habit Coach with Ashdin Doctor

Play Episode Listen Later Jun 30, 2021 10:15


Last week we started with our 'Hot Seat' episodes and we had a lot of requests and questions. This week we picked Malavika's question about how does one stay sane despite knowing the magnitude of challenges ahead? Ashdin tells her how we live in constant fear and that is leading to mental issues. Most challenges in our head don't exist yet and it is our mind that plays tricks on us. One must not get sucked into thinking of challenges of being huge, but instead, start thinking about them as things that will make us grow. Tune in for this and much more.Send questions to Ashdin Doctor Below.https://forms.gle/13vgf4MAk7zYKBd38Tune in to #TheHabitCoach with Ashdin Doctor.Check out the Awesome180 Habit Coach app: https://play.google.com/store/apps/details?id=com.awesome180.habitcoach&hl=en_IN&gl=USYou can follow Ashdin Doctor on Instagram @ashdindoc (https://www.instagram.com/ashdindoc/?hl=en)Check out Ashdin's website - Awesome180 (http://awesome180.com/)Youtube Channel: The Habit Coach - Awesome180: https://www.youtube.com/channel/UCZQpxuIf7moTOU8kCAu0ZfgYou can listen to this show and other awesome shows on the IVM Podcasts app on Android: https://ivm.today/android or iOS: https://ivm.today/ios, or any other podcast app.

Nanban Sathish - Tamil Podcast
"அணிலாடும் முன்றில்" முன்னுரை Anilaadum Mundril Na.Muthukumar Tamil Audio Book by Nanban Sathish

Nanban Sathish - Tamil Podcast

Play Episode Listen Later Jun 8, 2021 1:20


Tamil Audio book Anilaadum Mundril Na.Muthukumar Voice : Nanban Sathish

tamil muthukumar
Tamilan Podcast
Yuvan's admiration of Naa.Muthukumar

Tamilan Podcast

Play Episode Listen Later May 15, 2021 13:52


Details of the importance given to Lyricist Naa.Muthukumar by Music Genius Yuvan.

admiration muthukumar
Retailritesh Simplifying Retail
Business of Value Fashion- A candid conversation with Mr Muthukumar, Value Fashion Retail Guru

Retailritesh Simplifying Retail

Play Episode Listen Later Apr 20, 2021 23:19


Value fashion definition i.e. giving more value to customers than what he/she is paying for the apparel. future of value fashion. Entrepreneurial journey from finance to the world of fashion retail - amazing insights working with retail legends like Mr Mickey Jagtiani (founder, Landmark group).

De-Lyrically with Maaya - Tamil Podcast
Episode 7-Idhayam indha Idhayam

De-Lyrically with Maaya - Tamil Podcast

Play Episode Listen Later Mar 6, 2021 11:13


The song of this week is Idhayam indha Idhayam from the film Billa II written by Na. Muthukumar and sung by Shweta Pandit. To write Feedback or For Song/lyrics requests: write to me on delyrically@gmail.com. To listen more: Follow me on Instagram @_.minnalthuli._ . For instant updates: Follow me on Anchor @anchor.fm/maaya6 --- Send in a voice message: https://anchor.fm/maaya6/message

anchor muthukumar indha for song
De-Lyrically with Maaya - Tamil Podcast
Episode 3-Muzhumadhi Avaladhu

De-Lyrically with Maaya - Tamil Podcast

Play Episode Listen Later Jan 23, 2021 11:29


The song of this week is Muzhumadhi Avaladhu[ on request from Aishwarya Grace :) ] from the film Jodha Akbar written by Na.Muthukumar and sung by Srinivas. To write Feedback or For Song/lyrics requests: write to me on delyrically@gmail.com. To listen more: Follow me on Instagram @_.minnalthuli._ . For instant updates: Follow me on Anchor @anchor.fm/maaya6 --- Send in a voice message: https://anchor.fm/maaya6/message

anchor srinivas muthukumar for song
Quick Gun Rangan
6: Putham Pudhu Kaalai Tamil Anthology Review By Baradwaj Rangan | Quick Gun Rangan

Quick Gun Rangan

Play Episode Listen Later Nov 12, 2020 6:10


#PuthamPudhuKaalai (https://www.youtube.com/results?search_query=%23PuthamPudhuKaalai) is aTamil-language anthology film, consisting of five short film segments, directed by #SudhaKongara (https://www.youtube.com/results?search_query=%23SudhaKongara) , #GauthamMenon (https://www.youtube.com/results?search_query=%23GauthamMenon) , Suhasini Maniratnam, Rajiv Menon, and #KarthikSubbaraj (https://www.youtube.com/results?search_query=%23KarthikSubbaraj) . The film features an ensemble cast of Jayaram, Urvashi, Kalidas Jayaram, Kalyani Priyadarshan, M. S. Bhaskar, Ritu Varma, Shruti Haasan, Suhasini Maniratnam, Anu Hasan, Kathadi Ramamurthy, Komalam Charuhasan, Andrea Jeremiah, Gurucharan C, Leela Samson, Bobby Simha, Sharath Ravi, K. Muthukumar among others.

PaperPlayer biorxiv neuroscience
CUB and Sushi Multiple Domains 1 (CSMD1) opposes the complement cascade in neural tissues

PaperPlayer biorxiv neuroscience

Play Episode Listen Later Sep 12, 2020


Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.09.11.291427v1?rss=1 Authors: Baum, M. L., Wilton, D. K., Muthukumar, A., Fox, R. G., Carey, A., Crotty, W., Scott-Hewitt, N., Bien, E., Sabatini, D. A., Lanser, T., Frouin, A., Gergits, F., Havik, B., Gialeli, C., Nacu, E., Blom, A. M., Eggan, K., Johnson, M. B., McCarroll, S. A., Stevens, B. Abstract: Schizophrenia risk is associated with increased gene copy number and brain expression of complement component 4 (C4). Because the complement system facilitates synaptic pruning, the C4 association has renewed interest in a hypothesis that excessive pruning contributes to schizophrenia pathogenesis. However, little is known about complement regulation in neural tissues or whether such regulation could be relevant to psychiatric illness. Intriguingly, common variation within CSMD1, which encodes a putative complement inhibitor, has consistently associated with schizophrenia at genome-wide significance. We found that Csmd1 is predominantly expressed in the brain by neurons, and is enriched at synapses; that human stem cell-derived neurons lacking CSMD1 are more vulnerable to complement deposition; and that mice lacking Csmd1 have increased brain complement activity, fewer synapses, aberrant complement-dependent development of a neural circuit, and synaptic elements that are preferentially engulfed by cultured microglia. These data suggest that CSMD1 opposes the complement cascade in neural tissues. Copy rights belong to original authors. Visit the link for more info

Vina Podcast
E10- Na. Muthukumar - A celebration | ft. Maathevan Thiyagarajan, Sowmya Raman & Naveen

Vina Podcast

Play Episode Listen Later Jul 25, 2020 60:10


In this light hearted episode, we discuss why Na. Muthukumar as a person is one to be celebrated and why his songs are so special and very close to our hearts. --- Send in a voice message: https://anchor.fm/vina-podcast/message

Quick Gun Rangan
3: 2.0 Tamil Movie Review By Baradwaj Rangan | Quick Gun Rangan

Quick Gun Rangan

Play Episode Listen Later Jul 23, 2020 3:20


2.0, is a 2018 Indian 3D sci-fi action film, directed by S. Shankar and co-written by Shankar with B. Jeyamohan. The film was produced by Subaskaran Allirajah and Raju Mahalingam under the banner Lyca Productions. A spiritual successor to Enthiran (2010), it features Rajinikanth reprising the roles of Dr. Vaseegaran and Chitti, alongside Akshay Kumar and Amy Jackson. Sudhanshu Pandey, Adil Hussain, Kalabhavan Shajohn, and Dr K. Ganesh appear in supporting roles. The soundtrack was composed by A. R. Rahman, with lyrics written by Madhan Karky and Na. Muthukumar.

Geomob
Ed talks with Muthukumar Kumar of Geoawesomeness

Geomob

Play Episode Listen Later May 10, 2020 24:16


Ed chats with Muthukumar Kumar: navigation engineer, maker of leading geo blog Geoawesomeness, and the person who got GeomobMUC going. Show notes on the Geomob website.

kumar ed talks muthukumar
PaperPlayer biorxiv neuroscience
A splicing isoform of GPR56 mediates microglial synaptic refinement via phosphatidylserine binding

PaperPlayer biorxiv neuroscience

Play Episode Listen Later Apr 25, 2020


Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.04.24.059840v1?rss=1 Authors: Li, T., Chiou, B., Gilman, C. K., Luo, R., Koshi, T., Yu, D., Oak, H. C., Giera, S., Johnson-Venkatesh, E., Muthukumar, A. K., Stevens, B., Umemori, H., Piao, X. Abstract: Developmental synaptic remodeling is important for the formation of precise neural circuitry and its disruption has been linked to neurodevelopmental disorders such as autism and schizophrenia. Microglia prune synapses, but integration of this synapse pruning with overlapping and concurrent neurodevelopmental processes remains elusive. Adhesion G protein-coupled receptor ADGRG1/GPR56 controls multiple aspects of brain development in a cell type-specific manner: in neural progenitor cells, GPR56 regulates cortical lamination, whereas in oligodendrocyte progenitor cells, GPR56 controls developmental myelination and myelin repair. Here, we show that microglial GPR56 maintains appropriate synaptic numbers in several brain regions in a time- and circuit-dependent fashion. Phosphatidylserine (PS) on pre-synaptic elements binds GPR56 in a domain-specific manner, and microglia-specific deletion of Gpr56 leads to increased synapses as a result of reduced microglial engulfment of PS+ pre-synaptic inputs. Remarkably, a particular alternatively spliced isoform of GPR56 is selectively required for microglia-mediated synaptic pruning. Our present data provide a ligand- and isoform-specific mechanism underlying microglial GPR56-mediated synapse pruning in the context of complex neurodevelopmental processes. Copy rights belong to original authors. Visit the link for more info

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Quarantine series Ep02:A rare artist

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Play Episode Listen Later Apr 18, 2020 4:36


One fine sunny morning in chennai,happened to witness a masterpiece.I take this chance to provide a tribute to the producers of my favourite song Paravaiye Engu irukirai from Katradhu Tamizh..Hail Raja-Yuvan-Ram-Na.Muthukumar