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Melvyn Bragg and guests discuss the most abundant lifeform on Earth: the viruses that 'eat' bacteria. Early in the 20th century, scientists noticed that something in their Petri dishes was making bacteria disappear and they called these bacteriophages, things that eat bacteria. From studying these phages, it soon became clear that they offered countless real or potential benefits for understanding our world, from the tracking of diseases to helping unlock the secrets of DNA to treatments for long term bacterial infections. With further research, they could be an answer to the growing problem of antibiotic resistance.With Martha Clokie Director for the Centre for Phage Research and Professor of Microbiology at the University of LeicesterJames Ebdon Professor of Environmental Microbiology at the University of BrightonAnd Claas Kirchhelle Historian and Chargé de Recherche at the French National Institute of Health and Medical Research's CERMES3 Unit in Paris.Producer: Simon TillotsonIn Our Time is a BBC Studios Audio ProductionReading list: James Ebdon, ‘Tackling sources of contamination in water: The age of phage' (Microbiologist, Society for Applied Microbiology, Vol 20.1, 2022) Thomas Häusler, Viruses vs. Superbugs: A Solution to the Antibiotics Crisis? (Palgrave Macmillan, 2006)Tom Ireland, The Good Virus: The Untold Story of Phages: The Mysterious Microbes that Rule Our World, Shape Our Health and Can Save Our Future (Hodder Press, 2024)Claas Kirchhelle and Charlotte Kirchhelle, ‘Northern Normal–Laboratory Networks, Microbial Culture Collections, and Taxonomies of Power (1939-2000)' (SocArXiv Papers, 2024) Dmitriy Myelnikov, ‘An alternative cure: the adoption and survival of bacteriophage therapy in the USSR, 1922–1955' (Journal of the History of Medicine and Allied Sciences 73, no. 4, 2018)Forest Rohwer, Merry Youle, Heather Maughan and Nao Hisakawa, Life in our Phage World: A Centennial Field Guide to Earth's most Diverse Inhabitants (Wholon, 2014)Steffanie Strathdee and Thomas Patterson (2019) The Perfect Predator: A Scientist's Race to Save Her Husband from a Deadly Superbug: A Memoir (Hachette Books, 2020)William C. Summers, Félix d`Herelle and the Origins of Molecular Biology (Yale University Press, 1999)William C. Summers, The American Phage Group: Founders of Molecular Biology (University Press, 2023)
I had a profound and heart-wrenching conversation with renowned infectious disease specialist Steffanie Strathdee. Steffanie is Canadian-born and named by Time Magazine as one of the 50 most influential people in healthcare. She has written a book titled The Perfect Predator. A Scientists race to save her Husband from a Deadly Superbug. Steffanie's story unfolds like a gripping thriller. On holiday in Egypt, with her husband Tom, a deadly Superbug hijacks his body and it has Superpowers. It steals genes from other bacteria and the environment to resist antibiotics. This Superbug isn't an anamoloy. 5 million people will die from these types of infections in 2024. By 2050, that number is predicted to be 10 million. Why? The misuse and overuse of antibiotics in medicine and animal husbandry. Tom is airlifted to Germany, where the doctors aren't only perplexed, they are terrified as in the past this Superbog has shut down entire hospitals. They can do nothing, so Tom is Medevaced to the US. Fighting for his life, his organs shutting down, Tom is running out of time. Steffanie is desperate. She sees a psyche, hears about a century-old forgotten cure developed by a French Canadian but must enlist a dream team to try to save his life. What they uncover might save millions of lives, including yours and mine. To buy Steffanie and Tom's Book: The Perfect Predator. A Scientist's Race to Save Her Husband from a Deadly Superbug. https://www.amazon.com/Perfect-Predator-Scientists-Husband-Superbug/dp/0316418080 Time Code: 00:00 I introduce Stephanie Strathdee, An influential Scientist in infectious diseases. 04:48 Super Bugs are a Global Issue - 5 million deaths 05:57 Why aren't antibiotics working the way they used to? 07:54 Global agencies urge action and lack accountability measures. 10:41 The Perfect Vacation turns on a dime - A Super Bug invades Tom's body 12:40 Epidemiologist in Germany shocked by a deadly antibiotic-resistant bacterium. 15:38 Germans send Tom to the United States; nothing they can do 18:02 Tom is dying; a squeeze from his hand changes everything 24:57 Phage could be the cure but against all odds 29:48 Phage preparation to remove toxic bacteria so treatment doesn't kill Tom 30:52 Steffanie must make a life-and-death decision 34:07 Tom treasures life and moments together; phage therapy is a last attempt. 36:18 Phage saved Tom; can it save you and me? 37:48 Was this a miracle? 39:51 Tony's Three Takeaways 41:51 Tony's holiday message to you 43:50 Tony's Holiday Message
In recognition of World AMR Awareness Week (WAAW), Steffanie Strathdee, Associate Dean of Global Health Sciences and Harold Simon Distinguished Professor in the Department of Medicine at the University of California San Diego School of Medicine, joined the AMR Action Podcast to share the story of how her husband's case of “Iraqibacter” led her to find a phage therapy that saved his life. Steffanie also shares her thoughts on opportunities for Canada to lead on AMR innovation, and the resources and regulations required to make phage therapy available as an alternative to antimicrobials in health settings across the United States, Canada and the world.Read Steffanie's book: The Perfect Predator: A Scientist's Race to Save Her Husband from a Deadly Superbug: A MemoirLearn more about Phage Canada.
TDAgiantslayer@gmail.com WellBuiltBody.com Wake the faith up INTRO: you could easily take the next 5-8 podcasts and throw me under the bus… so listen to my heart, listen to all of the podcasts and wait for the last final podcast on this topic before you judge. 5 Things a Godly woman does for her husband. Respect - CHECK Love - Check Honor - Next up Serve Submit *and what's their problem if they can't do these 5 things. *A mans responsibility to make it easier Honor GK tee-may accord honor, pay respect") – properly, perceived value; worth (literally, "price") especially as perceived honor – i.e. what has value in the eyes of the beholder; (figuratively) the value (weight, honor) willingly assigned to something. Lets dumb this down for those who went to public school like me: You honor your husband and his value… and why is he valuable? Because he saw the value in you, and chose you above others. It's like this - someone gives you a brand new Zora Corvette - it is a limited production corvette, very rare… do you honor the car and take care of it? Yes… but you also honor the person who gave it to you because they chose you. Ladies, you are given a Saint Laurent handbag valued at 4k… do you honor and take care of that YES - do you also honor the person who gave it to you? Yes. You don't honor your husband because you are subservient, and he demands it, and scripture commands it… no. Think about it - he could date a hundred different woman, for a hundred different reasons… but he honored you by choosing you and now you can honor his decision by honoring him. The danger when we speak of this post marriage is women disguise their lack of honor by saying… well if I had known then what I know now- I would have married someone who loved me better, took care of me better, made my life easier - AND THEN I WOULD HONOR THEM. Again, thats not honor, that is blackmail. I am not saying if your husband is violent, abusive (and lets be honest, that term is overused in todays world… but anyway) if you are physically in danger, get out, move out, divorce him. But usually in todays world we think that if marriage isn't easy, we married the wrong person. Everyone marries the wrong person… everyone is a mismatch. Lets chase a rabbit for a second… our enemy satan blows things out of proportion when it comes to marriage issues because he knows it causes greater destruction… Ok, again let me explain. When we hear a sermon on “love your neighbor as you love yourself” We realize we need Gods help, his strength, his wisdom, his grace in order to love our neighbors (and neighbor means anyone we are currently around in life) if this was a sermon we would all say amen, yes I need to work on that. But when it comes to our spouse… our husband, we cringe, we lash out, we make excuses, we falter, we blow it off - because again, if satan can get us to neglect the responsibilities God has given us for marriage he knows it will destroy the family and ultimately America. God is so in love with the idea of marriage - he created it and he uses it as his example of the church and the Father. Now I will say it again… what I am called to do during hard times, suffering, discouragement… especially in marriage - what I am called to do is gut busting hard - but I won't waste this opportunity to call on Gods grace and allow his spirit to flow in me, through me and make me more like Jesus. Ladies, is it hard to Love, Respect and Honor your husbands? Don't waste this opportunity to be more like Jesus.
TDAgiantslayer@gmail.com WellBuiltBody.com Wake the faith up INTRO: you could easily take the next 5-8 podcasts and throw me under the bus… so listen to my heart, listen to all of the podcasts and wait for the last final podcast on this topic before you judge. 5 Things a Godly woman does for her husband. Respect - CHECK Love - NEXT UP Honor Serve Submit *and what's their problem if they can't do these 5 things. *A mans responsibility to make it easier I will again admit in todays world many women wince and actually manifest visible agitation when one mentions loving their husband… as if it is their only job when it comes to their role as a wife. Love your husband. But again I believe God knows what he is doing when he writes in his word… Titus 2:4 wives “to love their husbands.” What are types of love a Godly woman should give her husband? First lets admit.. men are imperfect, flawed and broken - and with that being said maybe the most important aspect of loving your husband is unconditional acceptance.accept your husband just as he is—an imperfect person. It's pretty simple, you can stop loving your husband when he becomes perfect… and he can stop loving you when you become perfect. Point being - love is only truly love when you love those who at the moment have not earned it - for if one must earn love, they are not truly being loved, only rewarded according to our standard. I sure don't want God to hold that type of love over me… Because I could never meet his standard. Second great way to love your husband is to tell him how much you love his Godly traits… yes, he may not have many, but the more you point those out and love him for them you will notice more, and you help nurture even more Christ like behavior. Remember God calls us to repentance by his kindness… it is your kindness to your husband that leads to greater alignment to who God is… that is a part of repentance. Love also means committing to a mutually fulfilling sexual relationship. I knew it was going to come down to sex again… just like a male podcaster to push sex. Actually last time I brought this up I had a few women give me some push back…and I get it, however scripture tells wives not to deny their husbands sex… Yes… there is a whole lot more to love than sex, but lets look at how to fulfill God's command to love your husband. So you gotta look at love from their perspective, not just your own. again and again Surveys show that sex is one of a man's most important needs—if not the most important from his wife. - and it todays culture there are many options for temptation to crawl in and many doors satan will open for the man who's wife is not willing to love her husband in bed. Scripture is clear 1 Cor. 7:5 So don't refuse sex to each other, unless you agree not to have sex for a little while, in order to spend time in prayer. Then Satan won't be able to tempt you because of your lack of self-control. When a wife resists intimacy, or is uninterested, or is only passively interested, or its the old “just go ahead” with the enthusiasm of a dead fish - her husband will feel like he is an inconvenience to her… Like “was I a mistake you made in marrying me? her husband may feel rejection. It will eat away at his self-image, and create distance and isolation in the relationship. And the sad thing is that women don't see the cycle they have just created in their marriage… They reason “well he is so disconnected why would he think I would want to have sex with him” Break that pattern now for the sake of your marriage. Let me read a quote from Barbara Rainey who is a leading expert in Christian marriage. My husband's sexual needs should be more important and higher on my priority list than housework, projects, activities, and even the children. It does not mean that I should think about sex all day and every day, but it does mean that I find ways to remember my husband and his needs. It means I save some of my energy for him. This keeps me from being selfish and living only for my own needs and wants. Maintaining that focus helps me defeat isolation in our marriage. The truth is that if a mans number one temptation in life is sexual in nature… it must also be his number one need… and only one person in the whole world is given that responsibility to fulfill it.
TDAgiantslayer@gmail.com WellBuiltBody.com Wake the faith up INTRO: you could easily take the next 5-8 podcasts and throw me under the bus… so listen to my heart, listen to all of the podcasts and wait for the last final podcast on this topic before you judge. 5 Things a Godly woman does for her husband. Respect Love Honor Serve Submit *and what's their problem if they can't do these 5 things. *A mans responsibility to make it easier The woman who hated her husband and wanted to divorce him. She went to a lawyer… how much do you hate him, do you want him to suffer… Conclusion Why would I ever divorce such a loving amazing man Nancy Anderson wrote an amazing article for Crosswalk regarding loving your husband through respect. She states she and her husband were on the brink of divorce…and he was argumentative, defensive and angry… but she realized he was only that way because of her lacking respect and being controlling. She was convicted and came up with 3 things that I don't think I can improve on. VIP Verbal respect: pull back on arguing, complaining and pointing out what is lacking and add more compliments, verbal affection Verbal respect is like the seasoning in your marriage I intellect Respect your husbands intellect. How many women treat their husbands like they are just stupid. They speak and act with disdain towards him. Men want to fix things… let them. Thank them for their opinion and then let them know how you feel afterwards and that you will think and pray over their thoughts. Instead of telling them their wrong, ask them KINDLY to explain their opinion or ideas behind what they say. *truth be told there is very very very little that is actually right or wrong… its always a matter of opinion. Women do not disrespect your husband intellectually just because his opinion is different… its not wrong, just different. P is for Physical Respect your husband physically. How you look… yes your physical appearance, How you take care of his physical needs (laundry, cooking, how the kids are taken care of) Physical as in sexual needs. Ladies, if you are listening… there are a lot of men out there who are trying,,,, sincerely trying… they are not perfect - they are burning out… they won't leave you - but they are checking out mentally, emotionally, physically… not out of hate or bitterness, but out of self preservation. Their fuel is respect, it feeds them… and you are not giving it to them and they are pulling back just in order to survive.
As the world continues to evolve toward advances in technology, the sciences, and globalization, it's important to reflect on the real-world gains of such progressions as well as the future opportunities that exist. In the case of this episode, the gains are associated with saving lives and combating the emerging threat of antimicrobial resistance and antibiotic resistant infections, which have been deemed by The World Health Organization as one of the top 10 global public health threats facing humanity. This episode is Part 2 of a series that focuses on AMR and the innovations in science and technology that are helping to tackle the challenge. The episode also points toward the connection between the issues of climate change and AMR as well as the opportunities to combine forces and develop collaborative efforts in addressing these threats. The episode digs deeper into innovations happening within healthcare to defeat superbugs as shared from the perspective of this episode's guest, Dr. Steffanie Strathdee, who is an Epidemiologist, Distinguished Professor, Global health solution-seeker, TEDx speaker, and Author of The Perfect Predator, a memoir of her effort to save her husband's life and the discovery of a forgotten cure that has the potential to save millions more. Steffanie also serves as Co-Director of the Center for Innovative Phage Applications & Therapeutics at the University of California, San Diego, School of Medicine as well as the Associate Dean of Global Health Sciences. Other topics range from the importance of advocacy and collaboration to tackle global health problems to how phages can help to evolve personalized medicine to how technologies like Machine Learning and Artificial Intelligence can be used to advance Phage Therapy. Also, is there a need for more health solutions to connect the dots when traveling abroad? For more details visit TechLink Health @ https://www.techlink.health or connect with Dr. Strathdee @ The Center for Innovative Phage Applications and Therapeutics. This episode was hosted by Rob McBride, Co-Founder and CEO of Felix Biotechnology and Dr. Sarah Samaan. The episode is packed with valuable insights and points to several references, including a direct email for those in need and interested in Phage Therapies as an alternative treatment:
On this week's Tuesday episode, the best friends decided they could not wait to discuss the sequel to The Bridge Kingdom, The Traitor Queen by Danielle L. Jensen! Join Yajaira and Cheli as they discuss the continuation of this fantasy world, the heartache the couple invokes and that unexpected ending! Passive AggressionA Midwestern look at hot button, taboo and dated topics with Kyle and Jess WassingListen on: Apple Podcasts Spotifyfollow us on Tiktok! ♡ https://www.tiktok.com/@thebookfix
Infectious Conversations: Getting a Grip on How to #SquashSuperbugs
In the newest episode of Infectious Conversations, Candace chats with Dr. Steffanie Strathdee: an infectious disease epidemiologist, the Associate Dean of Global Health Sciences at the University of California San Diego School of Medicine, and Co-director at the Center for Innovative Phage Applications and Therapeutics (IPATH). Dr. Strathdee relied on her extensive knowledge of infectious diseases to help save her husband's life using phage therapy after he developed a life-threatening, drug-resistant infection in 2016. The couple later wrote a book together titled “The Perfect Predator: A Scientist's Race to Save Her Husband from a Deadly Superbug,” which was published in 2019. To contact IPATH, email ipath@ucsd.edu.
Epidemiologist Steffanie Strathdee and her husband, psychologist Tom Patterson, were vacationing in Egypt when Tom came down with a stomach bug. What at first seemed like a case of food poisoning quickly turned critical, and by the time Tom had been transferred via emergency medevac to the world-class medical center at UC San Diego, where both he and Steffanie worked, blood work revealed why modern medicine was failing: Tom was fighting one of the most dangerous, antibiotic-resistant bacteria in the world.Steffanie joins Greg this episode to discuss solving her husband's medical crisis, and what she learned from this horrific experience. They also discuss how Covid has ramped these trends up, how critical phages are for our bodies, and the open mindedness of PhDs vs MDs.Steffanie is Associate Dean of Global Health Sciences and Harold Simon Distinguished Professor in the Department of Medicine at the University of California San Diego School of Medicine. She is also an Adjunct Professor at Johns Hopkins and Simon Fraser Universities. She co-directs UCSD's new center for Innovative Phage Applications and Therapeutics (IPATH), Global Health Institute and the International Core of UCSD's Center for AIDS Research. Stefanie has co-authored her memoir all about her husbands illness titled, “The Perfect Predator: A Scientist's Race to Save Her Husband from a Deadly Superbug.”Episode Quotes:The need for a phage library[30:40] What we need to do is build a phage library that maps onto a superbug library. And, of course, these are going to be constantly needing to be updated because these are organisms that are co-evolving to attack one another.What's the future looking for the advancement of phage[37:55] I can imagine a situation in the future, though, where, because we have, sequencers that are portable and cheaper than ever before, that you'd be able to sequence a phage and sequence a bacteria and be able to have a database to say, okay, you know, this phage will match that bacterium or to even genetically modify or synthesize a phage. So in a 3D printing model, some of my colleagues in Belgium have, you know, been working on that. So, I think that there's going to be advances that are going to help us make this work. But right now, we need phage libraries. We need more investment in clinical trials.Pushing beyond boundaries leads to discovery[39:49] When your back is up against the wall, whether it's you as an individual, us as a society, or a planet, we can sometimes have creative ideas to come up with solutions that we wouldn't otherwise do. And that's what I'm hoping that we'll do now because both climate change and antimicrobial resistance are colliding.Show Links:Guest Profile:Faculty Profile at UC San DiegoFaculty Profile at John Hopkins Bloomberg School of Public HealthProfessional Profile at Canadian Association for Global HealthSteffanie Strathdee on LinkedInSteffanie Strathdee on TwitterSteffanie Strathdee on InstagramSteffanie Strathdee on TEDxNashvilleHer Work:Steffanie Strathdee on Google ScholarThe Perfect Predator Website
As many reflect on the past couple of years of the pandemic and start to think about emerging threats of the future, it's important to bring awareness to that very topic, the future, and what's on the horizon in public health. This episode focuses on the emerging threat of antimicrobial resistance and antibiotic resistant infections, which have been deemed by The World Health Organization as one of the top 10 global public health threats facing humanity. During the episode we'll discuss the cutting edge technologies that can help tackle the challenge. This episode's guest is Rob McBride, PhD, Co-Founder and CEO of Felix Biotechnology, a technology focused on accelerating the deployment of novel biotherapeutics targeting urgent microbial challenges in human health and beyond. The Felix mission is founded on creating an evolutionary solution to the evolutionary problem of antimicrobial resistance. The company name pays homage to Félix d'Hérelle, a French-Canadian microbiologist who was known as the discoverer of bacteriophages (viruses that infect bacteria) and experimented with phage therapy. Rob has a PhD in Ecology and Evolutionary Biology from the University of Houston and a Bachelor of Science from Saint Vincent College in addition to a Postdoctoral Fellowship at Yale University. Prior to founding Felix, Rob was the Co-Founder of Boost Biomes, which used the powerful social networks among microbes to provide novel, sustainable solutions to feed and heal people everywhere. For more details visit TechLink Health @ https://www.techlink.health or connect with Felix @ https://www.felixbt.com/. This episode was hosted by Justine Reiss and Dr. Rodney Samaan. The episode unpacked many concepts related to Programmable Therapies such as Programmed Phage and also referenced an influential read on the topic:
In today's show, we sit down with Dr. Steffanie Strathdee, whose family story of saving her husband's life from a life-threatening superbug infection using phage therapy really inspired a lot of the most important works today in the phage therapy field. Listen to today's episode to learn about her story. Among her many roles, as the director of the 'Center for Innovative Phage Applications and Therapeutics' at UC San Diego, Dr. Strathdee also get to help us understand the scope of power we have today in our field and much more... Dr. Strathdee and her husband shared their story in their memoir "The Perfect Predator: A Scientists's Race to Save Her Husband from a Deadly Superbug", which can be found @ https://www.amazon.com/dp/B07H282CPT?ref=KC_GS_GB_US Their story has also recently been spread nationwide through CNN @https://www.cnn.com/2022/07/08/health/phage-superbug-killer-life-itself-wellness/index.html Find out more about UCSD IPATH and their resource @https://medschool.ucsd.edu/som/medicine/divisions/idgph/research/center-innovative-phage-applications-and-therapeutics/people/Pages/default.aspx Happy listening!
Dr. Steffanie Strathdee is Associate Dean of Global Health Sciences and Harold Simon Distinguished Professor in the Department of Medicine at the University of California San Diego School of Medicine. She co-directs UCSD's new center for Innovative Phage Applications and Therapeutics (IPATH), Global Health Institute and the International Core of UCSD's Center for AIDS Research. An infectious disease epidemiologist, she has spent the last two decades focusing on HIV prevention in marginalized populations and has published over 600 peer-reviewed publications. She has recently begun working to move bacteriophage therapy into clinical trials at IPATH. She has co-authored her memoir, The Perfect Predator: A Scientist's Race to Save Her Husband from a Deadly Superbug. In this podcast we talk about Dr. Strathdee's experiences learning about bacteriophage (phage) therapy treatment through a personal experience where her husband became extremely ill from antimicrobial resistant bacteria. She learned that stigma in part was how phage therapy had become forgotten in North America--stigma toward scientists with different beliefs and training than the mainstream, stigma toward viruses that maybe perceived "at the borderline of life", and stigma toward research based on geopolitics (including the "Russian taint"). Steffanie inspires listeners with her discussion of the power of global collaboration, advocacy in healthcare, and the importance of making (rather than waiting for) miracles to happen. Episode hosted by Dr. Carmen Logie. Supported by funding from the Canada Foundation for Innovation and Canada Research Chairs program. Original music and podcast produced by Jupiter Productions, who have various production services available to support your podcast needs.
In this week's episode of the Science Focus Podcast, we're joined by AIDS researcher Professor Steffanie Strathdee.In 2015, Strathdee's husband was infected by superbug that was resistant to every antibiotic that the doctors could throw at it, but she was able to save his life with an experimental treatment made of viruses found in sewage.In the New Year issue of BBC Science Focus Magazine, we cover the biggest ideas that you need to understand in 2021. This episode is one of a series in which we talk to the experts who will explain these ideas in their own words.Let us know what you think of the episode with a review or a comment wherever you listen to your podcasts.Subscribe to the Science Focus Podcast on these services: Acast, iTunes, Stitcher, RSS, OvercastListen to more episodes of the Science Focus Podcast:Marcus Chown: Does the Big Bang really explain our Universe?Sonia Contera: How will nanotechnology revolutionise medicine?Professor Catharina Svanborg: Is the cure for cancer hiding in human breast milk?Brian Switek: How did bones evolve?Bill Bryson: What should we know about how our bodies work?Dr Monty Lyman: What does our skin tell us about ourselves? See acast.com/privacy for privacy and opt-out information.
East Coast Radio — "If you had one ventilator and you had to choose to save your husband or your child, who would you save?" asks Thandolwethu.
No story of antibiotics would be complete without the rise of resistance. As promised in our last episode, this week we dive into what the WHO calls ‘one of the biggest threats to global health, food security, and development today’ - antibiotic resistance. In the decades since their development, misuse and overuse of antibiotics has led to many becoming all but useless, and our world seems on the verge of plunging into a post-antibiotic era. How does resistance work? Where did it come from? Why did it spread so far so rapidly? Is there any hope? In this episode, we answer all these questions and more. First, we explore the many ways bacteria evade the weaponry of antibiotic compounds. Then we trace the global spread of these resistant bugs by examining the major contributors to their misuse and overuse. And finally we assess the current global status of antibiotic resistant infections (spoiler: it’s very bad) and search for any good news (spoiler: there’s a lot!). To chat about one super cool and innovative alternative to antibiotics, we are joined by the amazing Dr. Steffanie Strathdee (Twitter: @chngin_the_wrld), Associate Dean of Global Health Sciences, Harold Simon Professor at the University of California San Diego School of Medicine and Co-Director at the Center for Innovative Phage Applications and Therapeutics. Dr. Strathdee provides a firsthand account of helping her husband, Dr. Tom Patterson, fight off a deadly superbug infection by calling on a long-forgotten method of treating bacterial infections: phage therapy. To read more about phage therapy and Dr. Strathdee’s incredible experiences, check out The Perfect Predator: A Scientist's Race to Save Her Husband from a Deadly Superbug: A Memoir.
"Never Give Up on Your Life" - John Haverty. John Haverty is a chef, a family man, a patient who was battling a stubborn bacterial infection in his leg for over 10 years. He wasn’t able to walk and put both feet on the ground for over 10 year. Doctors at Mayo Clinic were about to amputate John's leg as the last resort until a virus (called Phage Therapy) saved his life. Antibiotic resistance is now a public health crisis because we have these ’smart bacterial bug’ that can change and develop the ability to defeat the drugs that were designed to kill them. If you believe in miracle and want to believe in miracle, then this episode is for you and your loved one, who may be at struggling to find success with conventional Western Medicine and are considering to explore experimental therapy. Why is Antibiotic resistance is a serious public health issue? The causes of antibiotic resistance are due to many reasons such as: 1. Over-prescription of antibiotics 2. Patients not finishing the entire antibiotic course 3. Overuse of antibiotics in livestock and fish farming 4. Poor infection control in health care settings 5. Poor hygiene and sanitation 6. Absence of new antibiotics being discovered This episode will cover: 1. How John almost gave up on his leg until a supportive loved one helped him to find the courage to fight the last fight 2. What is phage therapy using Adaptive Phage Therapeutics 3. How can patient apply for the use of experimental therapy through the "compassion use clause with the Federal Drug and Administration (FDA)" 4 How phage therapy is administered in the clinic 5. What is the cost of phage therapy 6. How to advocate for your own life, because no one else will. Resources: 1. Connect with John Haverty by email at Chefjmh57@gmail.com 2. Learn more about the Adaptive Phage Therapeutics, a clinical-stage company founded to provide an effective therapy to global rise of multi-drug resistance pathogenic bacteria at http://www.aphage.com 3. Learn more about the research on phage therapy at University of California, San Diego (UCSD) https://medschool.ucsd.edu/som/medicine/divisions/idgph/research/center-innovative-phage-applications-and-therapeutics/Pages/default.aspx 4. Check out the book "The Perfect Predator: A Scientist's Race to Save Her Husband from a Deadly Superbug: A Memoir", by Stephanie Strathdee and Thomas Patterson 5. Connect with others on Facebook Group: Phage Page If you are interested in being a part of the invisible force called "Public Health" by sharing your story, please connect with the host, Dr. Kee Chan. Connect with on Linkedin http://www.linkedin.com/in/keechan and by email at keechanphd@gmail.com. --- Send in a voice message: https://anchor.fm/whatispublichealth/message Support this podcast: https://anchor.fm/whatispublichealth/support
Antimicrobial resistant infections are a major threat to global public health. In this month's episode, we explore using bacteriophages to combat these deadly infections. Niki Spahich from The Scientist's Creative Services team spoke with Jason Gill, associate director of the Center for Phage Technology at Texas A&M University, and Steffanie Strathdee, associate dean of Global Health Sciences at the University of California, San Diego, to learn more. The Scientist Speaks is a podcast produced by The Scientist's Creative Services Team. Our podcast is by scientists and for scientists. Once a month, we bring you the stories behind news-worthy molecular biology research. Special thanks to Dr. Steffanie Strathdee and Dr. Jason Gill for sharing their experiences. Steffanie Strathdee and Thomas Patterson's book about his illness is "The Perfect Predator: A Scientist's Race to Save Her Husband from a Deadly Superbug: A Memoir." More information can be found at ThePerfectPredator.com. If you enjoyed this episode, please subscribe to The Scientist Speaks on your favorite podcast platform.
On this episode, we are taking a closer look at the extremely real, human threat of antibiotic resistant infections, and discussing how momentum for beating these harmful bugs can start from just one person with a determination to find a solution. Co-host Matthew Wellington from U.S. PIRG interviewed Dr. Steffanie Strathdee, co-author of the book The Perfect Predator - A Scientist’s Race to Save Her Husband from a Deadly Superbug. Dr. Strathdee is the Associate Dean of Global Health Sciences, Harold Simon Professor at the University of California San Diego School (UCSD) of Medicine and Co-Director at the Center for Innovative Phage Applications and Therapeutics. In this episode, she tells the story of how her husband, Tom Patterson, was infected with a bacteria that was resistant to all available antibiotics and how doctors and researchers from around the world saved his life with a hundred year old forgotten cure—phage therapy—that shows promise as a weapon to tackle the global superbug crisis. Her husband co-authored the book with her and is also a renowned scientist at UCSD. To wrap up, Matt will dive into the news and updates currently chiming across the world of antibiotic resistance.
We can't say we weren't warned. More than 75 years ago, bacteriologist Rene Dubos cautioned that misuse of antibiotics could breed drug-resistant bacteria – and he has been proved prescient. In this episode: the rise of superbugs, why we ignored the warnings about them, how some are enlisting an old therapy to fight back, and whether we'll heed history's lessons in the face of a future pandemic. Plus, a weird unforeseen effect of antibiotics being investigated at the Body Farm. Guests: Fred Turek - Director of the Center for Sleep and Circadian Biology, Department of Neurobology, Northwestern University Jennifer DeBruyn - Microbiologist at the University of Tennessee, who also works at the Anthropology Research Facility, a.k.a. the Body Farm Steffanie Strathdee - Associate Dean of Global Health Sciences at the University of California, San Diego, and co-author (with Tom Patterson) of “The Perfect Predator: A Scientist's Race to Save Her Husband from a Deadly Superbug” Tom Patterson - Professor of Psychiatry at the University of California, San Diego, and co-author (with Steffanie Strathdee) of “The Perfect Predator: A Scientist's Race to Save Her Husband from a Deadly Superbug” Mark Honigsbaum - Medical Historian, journalist, and lecturer at City University, London, and author of “The Pandemic Century: One Hundred Years of Panic, Hysteria, and Hubris” Learn more about your ad choices. Visit megaphone.fm/adchoices
We can’t say we weren’t warned. More than 75 years ago, bacteriologist Rene Dubos cautioned that misuse of antibiotics could breed drug-resistant bacteria – and he has been proved prescient. In this episode: the rise of superbugs, why we ignored the warnings about them, how some are enlisting an old therapy to fight back, and whether we’ll heed history’s lessons in the face of a future pandemic. Plus, a weird unforeseen effect of antibiotics being investigated at the Body Farm. Guests: Fred Turek - Director of the Center for Sleep and Circadian Biology, Department of Neurobology, Northwestern University Jennifer DeBruyn - Microbiologist at the University of Tennessee, who also works at the Anthropology Research Facility, a.k.a. the Body Farm Steffanie Strathdee - Associate Dean of Global Health Sciences at the University of California, San Diego, and co-author (with Tom Patterson) of “The Perfect Predator: A Scientist’s Race to Save Her Husband from a Deadly Superbug” Tom Patterson - Professor of Psychiatry at the University of California, San Diego, and co-author (with Steffanie Strathdee) of “The Perfect Predator: A Scientist’s Race to Save Her Husband from a Deadly Superbug” Mark Honigsbaum - Medical Historian, journalist, and lecturer at City University, London, and author of “The Pandemic Century: One Hundred Years of Panic, Hysteria, and Hubris”
Absolute honour to have Dr. Steffanie Strathdee as my guest for episode 19. Dr. Strathdee is an infectious disease epidemiologist, Associate Dean of Global Health Sciences, Harold Simon Professor at the University of California San Diego School of Medicine and Co-Director at the Center for Innovative Phage Applications and Therapeutics. Herself and husband; Thomas Patterson, are also authors of the book 'The Perfect Predator: A Scientist's Race to Save Her Husband from a Deadly Superbug'.On the podcast we talk about Phage Therapy, what it is and the difference it can make in the Superbug Epidemic, the struggle Dr. Strathdee and her husband faced, recovery and everything that happened in between. I really hope you find it as fascinating and important as I did. Follow Dr. Strathdee on:Twitter - https://twitter.com/chngin_the_wrldInstagram - https://www.instagram.com/chngin_the_wrldCheck out Dr. Strathdee's University Profile here: https://profiles.ucsd.edu/steffanie.strathdeeFor more information on 'The Perfect Predator' head here: https://theperfectpredator.comPurchase the book: https://amzn.to/2Q50tnPFind out more about IPATH (Center for Innovative Phage Applications and Therapeutics):Website: https://bit.ly/2kGpg2HFacebook: https://www.facebook.com/IPATH/Twitter: https://twitter.com/IPATHContact IPATH: IPATH@ucsd.eduMake sure to give us a follow and give this episode a share, it helps the world and this is a topic which completely deserves it! Support the show (https://ko-fi.com/miztrujillo)
Kristin and Jane are joined by Professor Jonathan Iredell, ID and Microbiology Consultant at Westmead and Professor of Medicine and Microbiology and Sydney Medical School. We discuss: What is a bacteriophage? How can they help in a battle against antimicrobial resistance? How do we use them? What’s the dose and route of administration? Which infections can they be used for? How can they be regulated? What adverse effects can we expect from phage therapy? Further reading: The Perfect Predator: A Scientist's Race to Save Her Husband from a Deadly Superbug : A Memoir by Stephanie Strathdee and Thomas Patterson, available at the Book Depository Professor Iredell’s research page at Sydney Uni A review of phage therapy published this year by Patey and colleagues (Full text available)
Pan-resistant superbugs, world travel, a love story and the use of a virus to treat a life-threatening infection--and its all absolutely true. The makings of a great book. On this week's program, I am joined by the authors of The Perfect Predator: A Scientist's Race to Save Her Husband from a Deadly Superbug: A Memoir, Steffanie Strathdee and Tom Patterson. During the segment we look at the timeline, the research, the players and the wonderful outcome. The Outbreak News This Week Radio Show, the first and only radio program dedicated to infectious disease and health news and information, airs every Sunday at 1 pm ET in the Tampa Bay area on AM 1380 The Biz and online at http://1380thebiz.com/
Pan-resistant superbugs, world travel, a love story and the use of a virus to treat a life-threatening infection–and its all absolutely true. The makings of a great book. On this week’s program, I am joined by the authors of The Perfect Predator: A Scientist’s Race to Save Her Husband from a Deadly Superbug: A Memoir, Steffanie Strathdee […] The post Bacteriophages and ‘The Perfect Predator’ appeared first on Outbreak News Today.
Sometimes the personal is professional. It’s not all that common when ones work and one's survival is linked so inexorably together. They are in the story Tom Patterson and Steffanie Strathdee. Imagine, you're climbing a mountain, you slip and your spouse is the clinging to the rope above you and that’s the only thing keeping you alive. In the story of Tom and Steffanie, it was Steffanie clinging to science, history and medical bravery that Tom would have to hang on to. They tell their remarkable story in The Perfect Predator: A Scientist's Race to Save Her Husband from a Deadly Superbug: A Memoir My conversation with Tom Patterson & Steffanie Strathdee:
Finland is pretty happy right now. Not for any specific reason. They just are. Steffanie is also pretty happy, mostly because her husband is alive. Did you know that there are helpful viruses that eat bacteria? She certainly does. The Perfect Predator: A Scientist's Race to Save Her Husband from a Deadly Superbug: A MemoirBook Link-bit.ly/PerfectPredatorSee omnystudio.com/listener for privacy information.See omnystudio.com/listener for privacy information.
Delve into the realms of predatory superbugs with infectious disease epidemiologist Steffanie Strathdee and her husband, psychologist Thomas Patterson. This is an incredible story of Strathdee’s fight to save her husband’s life, which led her to rediscover a forgotten treatment for antibiotic-resistant bacteria. This unprecedented treatment saved Patterson’s life as well as several others and helped launch the Center for Innovative Phage Applications and Therapeutics (IPATH) at UC San Diego, the first phage therapy center in North America. Series: "Women in Science" [Health and Medicine] [Show ID: 34410]
Delve into the realms of predatory superbugs with infectious disease epidemiologist Steffanie Strathdee and her husband, psychologist Thomas Patterson. This is an incredible story of Strathdee’s fight to save her husband’s life, which led her to rediscover a forgotten treatment for antibiotic-resistant bacteria. This unprecedented treatment saved Patterson’s life as well as several others and helped launch the Center for Innovative Phage Applications and Therapeutics (IPATH) at UC San Diego, the first phage therapy center in North America. Series: "Women in Science" [Health and Medicine] [Show ID: 34410]
Delve into the realms of predatory superbugs with infectious disease epidemiologist Steffanie Strathdee and her husband, psychologist Thomas Patterson. This is an incredible story of Strathdee’s fight to save her husband’s life, which led her to rediscover a forgotten treatment for antibiotic-resistant bacteria. This unprecedented treatment saved Patterson’s life as well as several others and helped launch the Center for Innovative Phage Applications and Therapeutics (IPATH) at UC San Diego, the first phage therapy center in North America. Series: "Women in Science" [Health and Medicine] [Show ID: 34410]
Delve into the realms of predatory superbugs with infectious disease epidemiologist Steffanie Strathdee and her husband, psychologist Thomas Patterson. This is an incredible story of Strathdee’s fight to save her husband’s life, which led her to rediscover a forgotten treatment for antibiotic-resistant bacteria. This unprecedented treatment saved Patterson’s life as well as several others and helped launch the Center for Innovative Phage Applications and Therapeutics (IPATH) at UC San Diego, the first phage therapy center in North America. Series: "Women in Science" [Health and Medicine] [Show ID: 34410]
Delve into the realms of predatory superbugs with infectious disease epidemiologist Steffanie Strathdee and her husband, psychologist Thomas Patterson. This is an incredible story of Strathdee’s fight to save her husband’s life, which led her to rediscover a forgotten treatment for antibiotic-resistant bacteria. This unprecedented treatment saved Patterson’s life as well as several others and helped launch the Center for Innovative Phage Applications and Therapeutics (IPATH) at UC San Diego, the first phage therapy center in North America. Series: "Women in Science" [Health and Medicine] [Show ID: 34410]
Delve into the realms of predatory superbugs with infectious disease epidemiologist Steffanie Strathdee and her husband, psychologist Thomas Patterson. This is an incredible story of Strathdee’s fight to save her husband’s life, which led her to rediscover a forgotten treatment for antibiotic-resistant bacteria. This unprecedented treatment saved Patterson’s life as well as several others and helped launch the Center for Innovative Phage Applications and Therapeutics (IPATH) at UC San Diego, the first phage therapy center in North America. Series: "Women in Science" [Health and Medicine] [Show ID: 34410]
Delve into the realms of predatory superbugs with infectious disease epidemiologist Steffanie Strathdee and her husband, psychologist Thomas Patterson. This is an incredible story of Strathdee's fight to save her husband's life, which led her to rediscover a forgotten treatment for antibiotic-resistant bacteria. This unprecedented treatment saved Patterson's life as well as several others and helped launch the Center for Innovative Phage Applications and Therapeutics (IPATH) at UC San Diego, the first phage therapy center in North America. Series: "Women in Science" [Health and Medicine] [Humanities] [Show ID: 34410]