Podcasts about flagella

Tre morti in Toscana e un disperso in Veneto, è il bilancio, provvisorio, della tempesta che sta colpendo l'Italia, in particolare la Toscana e il Veneto.In Toscana un uomo di 85 anni è stato trovato morto ieri sera nella sua abitazione al piano terra di una casa a Montemurlo, nella frazione di Bagnolo, in via Riva.

To understand how organisms adapt to extreme environments, Marike Palmer and Brian Hedlund study organisms living in hot springs. Hear how their recent work revealed more about the history of the Chloroflexota phylum and a new way of moving: a tail-like flagella. Submit your own proposal to work with the JGIJoin us at the 2023 JGI User MeetingLinks from this episode:Episode TranscriptPublication: Palmer, M, et al.Thermophilic Dehalococcoidia with unusual traits shed light on an unexpected past The ISME Journal. (2023). doi: 10.1038/s41396-023-01405-0 Our contact info:Twitter: @JGIEmail: jgi-comms at lbl dot gov

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2023.07.16.549168v1?rss=1 Authors: Schrad, J. R., Fu, G., Hable, W. E., Tayar, A. M., Oliveira, K., Nicastro, D. Abstract: Cilia and flagella play a crucial role in the development and function of most eukaryotic organisms. The structural core of the flagellum, the axoneme, is conserved in most eukaryotes and careful regulation of dynein motors within the axoneme is required for proper ciliary beating. The sperm flagellum from the American eel (Anguilla rostrata) has been shown to lack many of the canonical axonemal proteins, including the radial spokes, the central pair complex, and possibly even the outer row of dynein arms, presenting a "minimal" flagellar system. Here, we present cryo-electron tomography analysis of the eel sperm flagellum. We identified two states for the eel sperm flagellum within our tomograms, narrow and wide, and found that the flagellum started narrow near the sperm head and widened distally. Subtomogram averages revealed that the eel sperm flagellum has retained remnants of the missing regulatory complexes, including a short radial spoke 3 complex, basal components of radial spokes 1 and 2, and an outer dynein arm docking complex. We also describe unique structural features of the A. rostrata sperm flagellum, such as a unique pattern of holes at the inner junction and an accessory complex located at the "outer" junction. Finally, we discuss the consequences of losing key regulatory factors for the eel sperm flagellum and hypothesize several evolutionary factors that may have led to their loss. Together, our results shed light onto the structure and function of the eel sperm axoneme and provide insight into the minimum requirements for proper ciliary beating. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC

3.01 Bacteria Basics   Microbio review for the USMLE Step 1 Exam: Bacteria are single-celled organisms that can cause infection Structural components of bacteria include: capsule, cell wall, flagella, fimbriae, plasma membrane, ribosomes, endospores, and DNA Capsules help bacteria evade the immune system by inhibiting phagocytes Flagella are tail-like appendages that allow bacteria to move, fimbriae help bacteria adhere to surfaces Most bacteria have a cell wall, which can be either gram positive or gram negative Plasma membrane is composed of proteins and phospholipids and performs various functions DNA is the genetic material, ribosomes are used to build proteins, some bacteria have endospores which are heat-resistant resting cells Bacteria can be classified by cell wall composition, morphology, metabolism, and based on their ability to grow at different temperatures and pH levels Gram staining is a laboratory technique used to differentiate between gram positive and gram negative bacteria Morphology of bacteria includes cocci (spherical), bacilli (rod-shaped), and spirilla (spiral-shaped) Metabolism of bacteria can be aerobic (uses oxygen) or anaerobic (doesn't use oxygen) Temperature and pH ranges at which bacteria can grow vary widely, some can grow at extreme conditions Pathogenic bacteria cause disease, while non-pathogenic bacteria do not Bacteria can be treated with antibiotics, but overuse can lead to antibiotic resistance

Il maltempo torna a provocare morti in Italia. La nuova ondata ha colpito il Centro Nord, con pioggia e forte vento. In Toscana hanno perso la vita un uomo e una donna.mgg/sat/redcredit immagini Toscana: Claudio Cuffaro/Fotogramma

Join me as I chat with Muffin's messy Bakery, who in all actuality couldn't be sweeter! They were all fun, and no shade, with a little tea!Follow them on IG:@alasdairflagella@iamdajonporter@botanyblackout

On today's ID the Future, author and biologist Michael Behe discusses with host Andrew McDiarmid how the once seemingly humble cilium is actually even more irreducibly complex than Behe suggested in his ID classic Darwin's Black Box—and indeed, even more complex than his review of cilia in his update in 2007. At the time Behe described cilia as “irreducible complexity squared.” But as noted in a recent article at Evolution News, even more layers of sophistication in cilia and their Intraflagellar Transport (IFT) system have now been discovered. So, does that mean we are now looking at irreducible complexity cubed? Listen in as Behe and McDiarmid revel in the engineering sophistication of this fascinating molecular machine, and discuss why, more Read More › Source

My AP Biology Thoughts  Unit 2 Cell Structure and FunctionWelcome to My AP Biology Thoughts podcast, my name is Saarim and I am your host for episode 54 called Unit 2 Cell Structure and Function: Movement Organelles. Today we will be discussing cilia and flagella, which are known as the movement organelles of the cell due to their importance in the movement and locomotion of cells through different means. I'll be starting off by giving an introduction to Cilia and Flagella (so, talking about their structure and what they both are exactly). Afterwards, I'll go through the variety of functions that cilia and flagella partake in and take on. Finally, I will place cilia and flagella into the broader scope of “cell structure and function” and expand a little bit on their importance and finish off by quickly presenting the consequences if cilia and flagella were absent. Segment 1: Introduction to Cilia and Flagella Cilia and flagella overview Tube like appendages that allow for motion in eukaryotic cells Cilia - found in both animals and microorganisms, but not in most plants Flagella - mostly used for motility in bacteria and gametes of eukaryotes Cilia structure Small hair-like protuberances on the outside of eukaryotic cells Responsible for locomotion of cell itself or of fluids on cell surface Involved in mechanoreception - detection/response of animals to stimuli Structure Made up of microtubules coated in plasma membrane Microtubules - small hollow rods made of protein tubulin Contains 9 pairs of microtubules forming the outside of a ring; two central microtubules (axoneme) - microtubules held together by cross-linking proteins Dyneins - motor proteins between the 9 outer pairs - allow cilia to be motile Proteins (hydrolyze ATP for energy) undergo conformational changes which allow for complex movements - cause the bending in the cilium as microtubules slide Cilia - 0.25 micrometers in diameter and 20 micrometers in length  Found on cell surface and beat back and forth to create movement Non-motile cilia Don't have the center microtubule structure or dynein arms - can't move Flagella structure Hair life organelles - longer and less numerous protrusions Used by cells and microorganisms for movement Specialized flagella in some organisms used as sensory organelles that can detect changes in temperature and pH Eukaryotic  Very similar to cilia Have 1+ (generally many) flagella which move in a whiplike way Core is a bundle of 9 pairs of microtubules surrounding 2 central microtubules like cilia, sliding of microtubules cause movement, etc. Depend on ATP for energy Prokaryotic/Bacterial Helically shaped structures that contain the protein flagellin Base of flagellum near the cell surface is attached to the basal body and the flagellum rotates in a clockwise or counterclockwise direction  Get energy from this proton motive force across the cell membrane Segment 2: More About Cilia and Flagella Cilia Function Important in movement of cell itself or of substances that go past the cell In ciliates, cilia responsible for the movement of the whole organism such as the unicellular protist Paramecium (cilia responsible for the movement and feeding) Help to remove contaminants from organs or tissues by helping to move fluids over the cell Lining of the nasopharynx and trachea covered in cilia - ciliated epithelial cells remove mucus, bacteria, and other debris from the lungs Present in the lining of the fallopian tubes - help in fertilization by movement of the egg towards the uterus Non-motile cilia Sensory apparatus for cell - detect signals Play roles in sensory neuron Found in the kidneys to sense urine flow In eyes on the photoreceptors of retina where they function to transport vital proteins from the inner segment of the photoreceptor to outer segment through sense and initiating movement Provide habitats for symbiotic microbiomes in animals Known to...

Episode 82Title: The Flagella Motor-High Tech in a Low-Tech WorldSubtitle: Thoughts on BeginningsAs we look toward the book of Genesis and the story of how things started, we will see that God's fingerprints are all over his creation. If you do not come to the knowledge of the truth that your survival and daily sustenance come from beyond the system, then the system will become your God and Savior, and from the looks of at the political systems that have come and gone in history, your long-term prognosis is grim if you are trusting in the constructs of man. The first book in the Bible, Genesis, starts off declaring, “In the beginning, God created the heavens and the earth.” The entire rest of the Bible rises or falls on this opening statement. Each human's right and privilege to self-governance & freedom rests on this fact. To deny this fact, makes you subservient to humans, who in the end, left to their own devices, always do the wrong things.The flagella motor imagesTaylor & Francis OnlineReview Article: The biophysicist's guide to the bacterial flagellar motorGraphic Image of the Flagellar Motorhttps://www.researchgate.net/figure/Schematic-diagram-of-the-proton-driven-bacterial-flagellar-motor-The-flagellar-motor_fig2_263513554https://www.nano.gov/Cut & Paste Personal Invitation to invite your friends to check out “gwot.rocks” podcast: I invite you to check out the podcast, “gwot.rocks: God, the World, and Other Things!” It is available on podcast players everywhere! Here is the link to the show's home base for all its episodes: http://podcast.gwot.rocks/ US>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>(Ctrl+click to follow the link) DONATE You can help support this podcast by clicking our secure PayPal account. For donation by check, make payable to Transform This City, P.O. Box 1013, Spring Hill, Tennessee, 37174. “gwot.rocks” is a ministry of Transform This City. gwot.rocks home page Transform This City Transform This City Facebook gwot.rocks@transformthiscity.org Digital Tools>>>>>>>>>>YouVersion The Bible App Multifaceted Bible with audio capabilities! Bible.Is Audio Bible The Bible Project The Bible Project Resources Plan of Salvation JESUS Film: This free full-length movie tells the story of Jesus and God's plan to redeem mankind to himself. The film is based on the Gospel of Luke and available in over 1,800 other languages. Thank you for listening! Please tell your friends about us! Listen, share, rate, subscribe! Unless otherwise noted, all Scripture quotations are taken from the Christian StandardBible®, Copyright © 2016 by Holman Bible Publishers. Used by permission. ChristianStandard Bible® and CSB® is a federally registered trademark of Holman Bible Publishers. See acast.com/privacy for privacy and opt-out information.

Thunderstorms, hailstorms and floods: the last week of August brought several Italian regions to their knees and caused victims and damage to infrastructure and agriculture. - Temporali, grandinate e allagamenti: l'ultima settimana di agosto ha messo in ginocchio diverse regioni italiane e provocato vittime e danni alle infrastrutture e all'agricoltura.

A Flagella-what? Episode 2 kicked off by Jensen this week, Schooling and fooling one another is kind of the game here! 

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.07.20.212191v1?rss=1 Authors: Ahmad, R., Kleineberg, C., Su, Y. J., Goli Pozveh, S., Bae, A. J., Bodenschatz, E., Sundmacher, K., Vidakovich-Koch, T., Gholami, A. Abstract: Artificial systems capable of self-sustained directed movement are of high interest with respect to development of many challenging applications including medical treatments but also technical applications. The bottom-up assembly of such systems in the context of synthetic biology is still a challenging task. Here, we demonstrate the biocompatibility and efficiency of an artificial light-driven energy module and a motility functional unit by integrating light-switchable photosynthetic vesicles with demembranated flagella, thereby supplying ATP for dynein molecular motors upon illumination. Flagellar propulsion is coupled to its beating frequency and the dynamic synthesis of ATP triggered by energy of light, enabled us to control beating frequency of flagella as a function of illumination. Light-powered functionalized vesicles integrated with different biological building blocks such as bio-polymers and molecular motors may contribute to bottom-up synthesis of artificial cells that are able to undergo motor-driven morphological deformations and exhibit directional motion in a light-controllable fashion. Copy rights belong to original authors. Visit the link for more info

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.07.20.212159v1?rss=1 Authors: Mojiri, S., Isbaner, S., Muehle, S., Jang, H., Bae, A. J., Gregor, I., Gholami, A., Enderlein, J. Abstract: Axonemes are the basic structure of motile cilia and flagella, and the investigation of how they function and move requires rapid three-dimensional imaging. We built a multi-plane phase-contrast microscope for imaging the three-dimensional motion of unlabeled flagella of the model organism Chlamydomonas reinhardtii with sub-m spatial and 4 ms temporal resolution. This allows us to observe not only bending but also the three-dimensional torsional dynamics of these small structures. We observe that flagella swim counter-clockwise close to a surface, with negatively-valued torsion at their basal and positively-valued torsion at their distal tips. To explain the torsional dynamics and signature, we suggest the existence of an intrinsic negative twist at the basal end that is untwisted by active positive-twist-inducing dynein motor proteins. Moreover, dyneins walking towards the basal induce an opposite twist at the distal tip. Bending of the whole axoneme structure then translates this twist into an observable torsion. This interconnection between chiral structure, twist, curvature, and torsion is fundamental for understanding flagellar mechanics. Copy rights belong to original authors. Visit the link for more info

The TWiM team reveals how ribosome modification resuscitates bacterial persister cells, and explain how a phage tail fiber protein exploits rotation of flagella to move towards the cell membrane. Become a patron of TWiM. Links for this episode: Ribosome modification resuscitates persister cells (Environ Micro) Flagellotrophic phage targets host with tail fiber (Mol Micro) Hydrodynamics of phage migration along flagella (Phys Rev Fluids) Music used on TWiM is composed and performed by Ronald Jenkees and used with permission. Send your microbiology questions and comments to twim@microbe.tv  

This audio/video overview by Dr. Ally Perlina of  goes in depth on Ben's latest gut microbiome results from . In this episode, you'll learn how to customize your diet and lifestyle based on the genetics of your gut. Dr. Perlina is the Chief Translational Science Officer at Viome. She leads the Viome team on the development of actionable pathway analytics, functional microbiome profiling, and integration of Viome test results into food and supplement recommendation logic. Ally came to Viome from working with Dr. Craig Venter at Human Longevity, Inc. She brings over 17 years of industry experience, which include Thomson Reuters, Quest Diagnostics, and several startup organizations where she led R&D groups, scientific product development efforts, and translated knowledge and insights from clinical data analyses into actionable results. S he’s a world-class expert in pathway analysis and translational systems biology, which are critical in addressing the complexities of health and disease from different data types in a meaningful holistic way. This cross-functional perspective and passion for making scientifically powered precision medicine insights actionable and scalable has been Ally’s driving force ever since she was investigating gene expression correlates of brain tumors and patient drug response at UCLA while getting her doctorate training in Human Genetics. Ally’s ability to “translate” the signals from genomics, transcriptomics, metabolomics, etc., into something valuable for human health today allows her to lead a diverse team of scientific, clinical, and nutritional experts that together with data science make truly personalized Viome recommendations with molecular-level precision To learn more about Viome and what it is, you can or check out these previous resources I've created on this cutting-edge way to test all the bacteria in your gut, along with the postbiotics they produce: - Article: - Podcast: - Podcast: - Podcast: During this audio/video, you'll discover: -Ben's GI summary...7:23 Most important themes to address are several specific functions dealing with digestive efficiency Active microbes: There are 134 active microbial species detected in the sample, which means that Richness is within the average range but may need improvement. No active Eukaryotes were detected There are 2 active plant viruses: Prunus necrotic ringspot Pepper mild mottle -Overall microbial richness...9:50 Ben's score is 134 out of 400; average score (5-95 percentile) The microbial could use a boost, but nothing too alarming Recommended foods: enriches and diversifies the microbiome increase microbial diversity contains MUFAs, which are a group of fatty acids; weight management, increases bacterial diversity, decreases inflammation Recommended supplements: and cranberry containing supplements -Metabolic fitness score...18:35 Ben's score is GOOD, in the 18th percentile of the Viome population (improved from Sep. 2018) -Inflammatory activity...21:10 Ben's overall score is AVERAGE LPS biosynthesis pathways: average Methane gas production pathways: needs improvement Sulfide gas production pathways: needs improvement Flagella assembly pathways: average Biofilm, chemotaxis, virulence pathways: average Balance is the goal, not optimal scores in every area Although the score is "average" it's on the higher end of the spectrum -Proinflammatory microbial activity, and active pro inflammatory pathways that indicate potential GI inflammation...32:40 -Butyrate production pathways and active butyrate producers...45:45 Ben's overall score is GOOD is good for metabolic fitness Regulates satiety, good for insulin sensitivity Goes hand in hand with inflammation scores Butyrate is a short chain fatty acid (SCFA); associated with beneficial functions for the host Resistant starches and fibers: resist the digestive system of the host -SCFA production pathways and active SCFA producing microbes...51:40 In addition to butyrate: acetate, acetyl phosphate Active probiotic in Ben's sample Many different pathways that lead to butyrate production -Recommendations for Ben's diet...55:23 (mammal) Phytometabolizing microbes and active pathways: -Digestive efficiency...59:20 Ben's overall score is AVERAGE Protein fermentation: needs improvement Gas production: needs improvement Methane gas production pathways: needs improvement Sulfide gas production pathways: needs improvement Putrescine production pathways: needs improvement Butyrate production pathways: good Salt stress pathways: good Protein fermenters and active protein fermentation pathways Omithine Putrescine Cadaverine Ammonia Urea Recommendations related to protein fermentation: Fennel bulb Alfalfa sprouts Grapefruit -Hydrogen sulfide production pathways and hydrogen sulfide producing microbes...1:15:50 Exacerbated by certain foods Disruptive to the gut lining Proinflammatory if produced in excess Sulfate (or sulfite) is deleterious Recommendations specific to microbial gas production, particularly hydrogen sulfide: Broccoli Brussels sprouts -Vitamins produced by the gut microbes and detox of the microbiome... -And much more... Resources mentioned: - Episode sponsors: -: My personal playground for new supplement formulations, Kion blends ancestral wisdom with modern science. Ben Greenfield Fitness listeners receive a 10% discount off your entire order when you use discount code: BGF10. -: I’ve been using Four Sigmatic products for awhile now and I’m impressed by the efficacies of their mushroom products. I use them. I like them. I support the mission! Receive 15% off your Four Sigmatic purchase when you use discount code: BENGREENFIELD -: You can be sure that I researched all the saunas before I bought mine and Clearlight was the one that stood out from all the rest because of their EMF and ELF Shielding and their Lifetime Warranty. Use discount code: BENGREENFIELD to get $500 off your sauna and a free bonus gift! -: As your qualified candidates roll in, we make it easy to screen & rate them, allowing you to make the best hiring decisions for your business. Try it for free when you use ! Do you have questions, thoughts or feedback for Dr. Ally or me? Leave your comments below and one of us will reply!  

The TWiM team considers the state of the world’s fungi as revealed by a report from the Kew Royal Botanical Gardens, and how Salmonella loses motility to evade host defenses. Hosts: Vincent Racaniello, Michael Schmidt, Elio Schaechter, and Michele Swanson Take our listener survey. Thanks! asm.org/twimpoll Subscribe to TWiM (free) on iTunes, Google Podcasts, Stitcher, Android, RSS, or by email. You can also listen on your mobile device with the Microbeworld app. Become a Patron of TWiM! Links for this episode: Subscribe to MicrobeTV on YouTube State of the World’s Fungi 2018 Salmonella loses motility to avoid inflammasome activation (Cell Rep) Music used on TWiM is composed and performed by Ronald Jenkees and used with permission. Send your microbiology questions and comments to twim@microbe.tv

The TWiM hosts and associated microbiomes review a fungus destroying salamanders in Europe, and genes for flagella in intracellular bacteria. Hosts:  Vincent Racaniello, Michael Schmidt, Michele Swanson and Elio Schaechter. Subscribe to TWiM (free) on iPhone, Android, RSS, or by email. You can also listen on your mobile device with the Microbeworld app. Become a patron of TWiM. Links for this episode Fungus killing fire salamanders (Nature) Chlamydia with flagella (ISME J) Flagellar movement in rickettsia (PLoS One) Image credit Letters read on TWiM 162 Send your microbiology questions and comments (email or recorded audio) to twim@microbe.tv This episode is brought to you by the Defense Threat Reduction Agency. Part of the U.S. Department of Defense, the Agency’s Chemical and Biological Technologies Department hosts the 2017 Chemical and Biological Defense Science & Technology Conference to exchange information on the latest and most dynamic developments for countering chemical and biological weapons of mass destruction. Find out more at http://www.cbdstconference.com  

Tubulin transport pumps up cilia The assembly of cilia and flagella requires the delivery of large amounts of tubulin to the growing ends of the organelles' microtubules. Craft et al. reveal that tubulin loading onto intraflagellar transport particles is specifically upregulated in growing cilia. This biosights episode presents the paper by Craft et al. from the January 19, 2015, issue of The Journal of Cell Biology and includes an interview with the paper's senior author, Karl Lechtreck (University of Georgia, Athens, GA). Produced by Caitlin Sedwick and Ben Short. See the associated paper in JCB for details on the funding provided to support this original research. Subscribe to biosights via iTunes or RSS View biosights archive The Rockefeller University Press biosights@rockefeller.edu

In this episode of the eLife podcast we learn more about sleep, super Spy chaperones, swimming bacteria, orphan genes and the neuroscience of birdsong. Get the references and the transcripts for this programme from the Naked Scientists website

Hosts: Vincent Racaniello and Dickson Despommier Vincent and Dickson tackle the backlog of listener email, then consider the life cycle and pathogenesis of Trichomonas vaginalis, the flagellated protozoan transmitted by sexual contact. Links for this episode: T. vaginalis life cycle (jpg) T. vaginalis hydrogenosome (jpg) Letters read on TWiP 38 Contact Send your questions and comments (email or mp3 file) to twip@twiv.tv.

This presentation discusses the movement of swimming cells. The effects of interaction between the flagella of different cells and the effects of wave geometry are also discussed.

Transcript -- Dr Gianfranco Novarino demonstrates how to isolate flagellates from samples and some of their more unusual feeding behaviour.

Dr Gianfranco Novarino demonstrates how to isolate flagellates from samples and some of their more unusual feeding behaviour.

Transcript -- Dr Gianfranco Novarino demonstrates how to isolate flagellates from samples and some of their more unusual feeding behaviour.

Dr Gianfranco Novarino demonstrates how to isolate flagellates from samples and some of their more unusual feeding behaviour.