Podcasts about Butyrate

What if aging isn't simply your body “wearing out”… but your body losing the ability to repair itself? In this episode, Dr. Andrew Salzman joins Dr. Josh Axe to explain why chronic inflammation, leaky gut, and depleted NAD may quietly drain the very energy your cells need to heal, think, move, and survive. Uncover what's really going on in your body with advanced biomarker testing for hormones, thyroid, and metabolism— plus a 1-hour consultation with a Senior Health Advisor! →  http://mybloodwork.com Thank you to our sponsors! Sunlighten Sauna: https://get.sunlighten.com/axepodcast Manukora Manuka Honey: https://manukora.com/axe Caraway Home: carawayhome.com/drjoshaxe (Use code DRJOSHAXE) for an exclusive discount Watch The Dr. Josh Axe Show every Monday & Thursday on YouTube: https://www.youtube.com/@drjoshaxe?sub_confirmation=1

Do you know your Butyrate status and why it matters? In this episode, Ali Miller RD, digs into short chain fatty acids and metabolites in the colon with a big emphasis on butyrate. This beneficial compound provides energy for the body while reducing inflammation, protecting your gut barrier, and improving colon cell health. With the rate of colorectal cancer on the rise of 2% increase per year, we need to pause and consider diet and lifestyle strategy.    You will learn foods to increase in your diet to support butyrate levels, how to address dysbiosis or gut infection, particular strains of gut flora that aid in production of butyrate, and how to assess your status in a stool test. Ali will discuss the importance of increasing fiber in your diet with a variety of sources and why eliminating or greatly limiting seed oils is key for colon health. This episode also covers the connection of environmental toxicity, considerations of your toilet paper choice, and if it's worth getting a bidet.    Links in this episode: Test your stool with a GI Map and get a customized interpretation from Ali Miller RD Shop my Beat the Heat Probiotic Promo Use BEATTHEHEAT26 to buy 2 get 1 50% off Choosing the Right Probiotic Guide Probiotic Challenge Protocol Restore Baseline Probiotic Rebuild Spectrum Probiotic Targeted Strength Probiotic  Episode 448 Naturally Nourished Podcast Do I really need a colonoscopy + All about Cologuard 40 Clove of Garlic Soup  

If foods you've eaten for years are suddenly leaving you bloated, uncomfortable or rushing to the loo, fluctuating hormones could be to blame. Liz explores how perimenopause can activate digestive discomfort and looks at ways to support the gut lining to improve symptoms.Plus: how to avoid injuries from strength training, managing acid reflux and indigestion, evening heart palpitations and can using a sauna reduce dementia risk?In this episode:•Are hormone fluctuations making me gluten intolerant?•Ways to manage heartburn and indigestion•Will using a sauna reduce my risk of dementia?•Advice for avoiding injuries when strength training•Why is my heartbeat so loud at night? Links mentioned in the episode:•Creatine - https://lizearlewellbeing.com/?s=creatine •Butyrate - https://lizearlewellbeing.com/?s=butyrate•The Good Gut Guide - https://shorturl.at/hwfDb•British Heart Foundation information on PPIs - https://www.bhf.org.uk/informationsupport/heart-matters-magazine/medical/drug-cabinet/proton-pump-inhibitorsGet in touch with a question for Liz: •Email: podcast@lizearlewellbeing.com•WhatsApp: 07518 471 846More from Liz:•Order Liz's new book – How to Age- https://www.amazon.co.uk/How-Age-Supercharge-Health-Better/dp/1399723715•A Better Second Half- https://www.amazon.co.uk/dp/1399723677?_encoding=UTF8&qid=1695723884&sr=8-1&linkCode=sl1&tag=lizearlewellb-21&linkId=5eefa1edb4d033e84befc25728bebcf0&language=en_GB&ref_=as_li_ss_tl•Follow Liz on Instagram- https://www.instagram.com/lizearleme/?hl=en•Follow Liz Earle Wellbeing on Instagram- https://www.instagram.com/lizearlewellbeing/?hl=enHost: Liz EarleProducer: Lynnike Swerts (Fresh Air Production)Social Media Manager: Naomi van GeelenContent Writer: Lucy ParleyHead of Brand: Ellie Smith Some links may be affiliate links, which help support the show at no extra cost to you. Read our Affiliate Policy for more information. Hosted on Acast. See acast.com/privacy for more information.

A Brand New Tool for Gut, Inflammation, and Brain Support: Holistic practitioner Jane Jansen details Essential Formulas' Dr. Ohhira's Postbiotic Fermented Food Concentrate, a non-GMO, gluten-free, dairy-free, capsule-free fermented paste in travel-friendly, non-refrigerated sachets. She explains the difference between probiotics and postbiotics, emphasizing that this concentrate delivers postbiotic metabolites (including short-chain fatty acids like butyrate, plus enzymes, amino acids, vitamins, peptides, and growth/repair factors) created via a five-year fermentation of 14 fruits, vegetables, mushrooms, and seaweeds; the paste contains no live probiotics because they are heat-killed. The discussion highlights use cases for people who don't tolerate fiber or probiotics (IBS, SIBO, Crohn's, ulcerative colitis), potential benefits for leaky gut, systemic inflammation, gut-brain/mitochondrial health, insulin resistance, children, and pets, and suggests it can complement Dr. Ohhira's capsules and may be taken less than daily.

In this video, Dr. Ruscio discusses 8 benefits of taking butyrate, a fat molecule with gut and systemic healing properties. Butyrate is produced by gut bacteria, but it is often low in different chronic health conditions. Supplementation has been shown to improve a variety of gut conditions, including IBS, IBD, and SIBO, as well as chronic inflammation and brain health. Doctor Ruscio also discusses some simple dietary strategies to increase butyrate production naturally.    ✅ Start healing with us! Learn more about our virtual clinic:  https://drruscio.com/virtual-clinic/  

Hosts: Ed Jones (Owner – Nutrition World) & Clint Powell A variety of topics all related to living a healthy life Presented by: Nutrition World www.nutritionw.com Broadcasting from the Nooga Dentistry Studio www.noogadentistry.com Production of: Whitfield Media Group www.vitalhealthradio.com Title: All About Peptides, & The Good, Bad & Ugly of GLP-1's [0:00:00]  Ed's Restaurant Story & Healthy Eating Choices Ed's recurring bit: “Where did Ed eat this week?” Long‑time favorite restaurant Epicurean. Discussion of consistent healthy ordering and making good choices at long‑standing, family‑owned restaurants. [0:03:13]  Building a Health “Team” & Ed's Top Learning Resources Tease of today's main topic: peptides with local expert Noel Lawson, NP. Ed stresses “team approach” to aging—no single practitioner has all the answers. Learners vs. non‑learners: why ongoing self‑education is critical for health. Ed's 4 favorite online resources: Mercola.com – more cutting‑edge, sometimes controversial content. DrJockers.com – accessible, visual education on ailments and nutrients. GreenMedInfo.com – indexed medical literature backing natural claims. Nutrition World Instagram – short, practical health “snippets”. Story: Nutrition World wins a surprise $10,000 award from Ancient Nutrition for #1 sales growth in the U.S., tied to belief in product quality. [0:10:38] Introducing Noel Lawson & “What Are Peptides?” Introduction of Noel Lawson, NP (Double Bridges Health & Wellness), now practicing on the Nutrition World campus. Noel's background: Transition from traditional medicine to functional medicine due to patient frustration, worsening chronic illness, and provider burnout. Goal: more prevention and root‑cause care. Orthopedic background led her to peptides. What is a peptide? Peptides are like the body's Morse code—specific chains of amino acids acting as signals. Under ~40 amino acids = peptide; longer chains = protein. Body breaks down dietary protein into amino acids and re‑assembles them into peptides as needed (e.g., for repair). As we age, the body produces fewer peptides, which is why we heal slower and are more prone to injury and inflammation. [0:19:26] Functional Medicine + Peptides: Approach, Expectations & Use Noel's approach: Combines functional medicine with peptides. Peptides only work well if the materials (sleep, nutrients, stress management, movement) are in place. Uses comprehensive labs to optimize baseline health first. Delivery & protocols: ~90% of peptides are injectable (tiny insulin‑type needle, usually daily). Some oral options exist Local injections near the injury area Expectations & timelines First 2–3 weeks: less inflammation, modest improvement in pain, sleep, and energy. 6–8 weeks: improved range of motion and strength. After 3 months: realistic minimum for true tissue change; peptides can't shortcut normal cell‑turnover timelines. [0:21:41] Specific Peptides & Treatment Logistics High‑demand musculoskeletal peptides: BPC‑157 and TB‑500: commonly used for tendons, ligaments, muscle and injury recovery. Growth hormone related peptides: Examples: samorelin, CJC, ipamorelin, tesamorelin. Stimulate the pituitary to release natural human growth hormone (HGH) rather than supplying exogenous HGH. Potential benefits: lean muscle mass, better body composition, cardiometabolic support. Monitored via IGF‑1 levels to avoid excess. PT‑141 for sexual health: Crosses the blood–brain barrier and activates pleasure/desire centers. Can cause nausea in some people; alternative forms (nasal spray, sublingual troche) may reduce side effects. How Noel works with patients: Website: doublebridgeswellness.com Contact form → email → optional free 20‑minute expectations call to see if there's a good fit. 1‑hour new patient visits, not rushed; she practices on the Nutrition World campus. [0:35:01] GLP‑1 Drugs (Ozempic, Trulicity, Mounjaro): Good, Bad & Ugly Case study: 65‑year‑old woman with pre‑existing gastroparesis put on Trulicity. Developed severe vomiting, dehydration, abdominal pain; was initially reassured to “get used to it.” Second dose led to life‑threatening pancreatitis, requiring hospitalization. Later prescribed Mounjaro by same clinic despite this history. The “Good” of GLP‑1s: In Curt's clinic, used selectively for: Poorly controlled diabetes (A1c > 10, average sugars in the 300s). Significant obesity. Can lower blood sugar and drive weight loss, by suppressing appetite The “Bad”: Common GI side effects (up to ~50% of users): Nausea, vomiting, constipation. Worsening gastroparesis (slow gut motility). Rapid weight loss often includes loss of muscle and bone, not just fat—hurts longevity and functional strength. Ozempic face: gaunt facial appearance from aggressive fat/muscle loss. Risk of hypoglycemia Visual issues, including increased macular degeneration risk. Psychiatric concerns: Emerging data on increased suicidal ideation, especially notable because trials excluded psychiatric patients. The “Ugly”: Pancreatitis, gallbladder problems. Thyroid tumors in some models. Possible cardiac atrophy. Massive growth in use: tens of millions prescribed, with many discontinuing within a year due to side effects or cost. Risk that people treat GLP‑1s as a “magic bullet” without nutrition or lifestyle change—and regain ~85% of lost weight after stopping. Curt's conclusion: GLP‑1s should be reserved for specific, high‑risk cases and paired with close coaching. For most people, there are safer, natural options. [0:50:12] “Nature's Ozempic,” Gut Health & Upcoming Events Ed and Curt on supporting GLP‑1 pathways naturally: Berberine – “nature's Ozempic” for blood sugar and metabolic support. Akkermansia (probiotic strain) – gut health, metabolic benefits, GLP‑1 stimulation. Butyrate – short‑chain fatty acid that: Supports gut lining / leaky gut repair. Improves colon health and may help increase GLP‑1. Ed reports best bowel function of his life using 2 caps/day. People who start GLP‑1s often increase supplement use, but tend to stop supplements when the drug stops. Coaching is needed so they maintain nutrition and supplementation after GLP‑1 discontinuation. Practical tips & announcements: Colonoscopies: clear protein drinks are now typically allowed on prep day—can help preserve muscle and stabilize blood sugar. Upcoming Lunch & Learn (online): Topic: “The Microbiome's Impact on Longevity”. Format: Instagram Live (@NutritionWorld), Tuesday, May 5 at 12:15 PM. Upcoming in‑person lecture at Nutrition World campus: Topic: “Taming the Yeast: Candida‑Reducing Strategies”. Thursday, May 21 at 5:30 PM. Registration via nutritionw.com → Events. Closing: Ed and Clint wrap up, reiterating their mission of clear, actionable health guidance and noting the show will be out on major podcast platforms. The post Radio Show / Podcast – May 3, 2026 first appeared on Vital Health Radio.

Ayurveda states: "The intestine in the brain of the brain", which has been backed by modern Western science to the point that now we know that, indeed, there are neurons in the intestine, which are not different from those found in the brain itself. Our modern diet, poor in healthy fibers and overabundant in processed foods, pesticides, and harmful artificial chemicals, is taking a toll on the health of "the brain of our brain", making diseases such as leaky guts far from a rarity these days. In this episode, Dr. Marianne Teitelbaum. explains how the human intestine functions, how modern lifestyle affects it, and how the magical properties of butyrate protect and restore its well-being. Some handy diet tips are also part of this erudite lecture packed with invaluable information.

What if the reason you still don't feel your best… has nothing to do with willpower and everything to do with what's happening deep inside your body? In this episode, I sit down with Jess Kane Berman of BodyBio, a family-founded company originally created by her grandfather and rooted in cellular health and science-backed solutions and this conversation completely reframed how I think about healing - from the cellular level to the emotional level.   We talk about what's really driving symptoms so many of us are experiencing right now - hormonal shifts, fatigue, brain fog, gut issues and why the answers might not be where you've been looking. Jess shares her personal journey through health struggles, how she navigated a diagnosis that left her feeling overwhelmed, and what ultimately helped her take her power back - guided in part by the foundational principles her grandfather pioneered and that still shape BodyBio's approach today.   We dive into the connection between stress, trauma, and the body - how what we carry emotionally can shape how we feel physically, and why slowing down is often where true healing begins. We also explore what it looks like to care for your body in today's world - reducing toxic load, making intentional choices without fear, and nourishing yourself at a level that supports deep, cellular health.   This is one of those episodes that invites you to zoom out, reconnect with your body, and rethink what it really means to heal. If you want to support your body at the cellular level, you can explore BodyBio and save 20% with code HEALWITHKELLY. Key Moments You'll Love ✨ :

#317 I'm a degree-qualified naturopath with over 20 years of clinical experience, with a primary focus on complex gut health conditions — and in this video, I'm doing something I've never done before. I'm turning the lens on myself. I recently got my own gut microbiome tested, and I want to walk you through every single result. I didn't get tested because I had gut symptoms — my bowels are actually moving beautifully. I got tested because I'd been dealing with over a year of persistent rosacea and wanted to know: could what's happening in my gut be connected to what's showing up on my skin? I also wanted to show you exactly what this test looks like when it's interpreted by someone who does this for a living. We cover every section of the report — the pathogen panel, the diagnostic GI markers, microbiome diversity and richness, short-chain fatty acids, TMA, emerging metabolites, the species table, and more. I also share the result that was flagged as severely abnormal — and why, in context, it almost certainly isn't. This is what it looks like to use real data to motivate real change — not because something has gone terribly wrong, but because catching the trajectory early is the whole point. What we cover What makes shotgun metagenomics different from other stool tests The targeted pathogen panel — what it tests for and what my results showed Pancreatic elastase — the result that flagged severely low, and why context changes everything Lactoferrin, calprotectin, zonulin, secretory IgA, and faecal occult blood Microbial diversity and richness — what we're aiming for and why it matters Butyrate, acetate, propionate, and TMA — what they mean and how diet influences them Prevotella copri — nuanced, misunderstood, and more common in traditional diets than you'd think Emerging markers, including GABA, and why we need to hold them lightly Human DNA elevation — and why collection context explains it My action steps and why seeing this data now motivates me to act I'm Lynda Griparic, a degree-qualified naturopath with extensive experience in complex gut health conditions, including SIBO, IMO, and chronic constipation. Book a consultation or shop BetterMe Tea at lyndagriparic.com This content is for educational purposes only and is not intended as medical advice. Please consult with your healthcare provider before making any changes to your health routine.

You used to digest everything. Now a salad wrecks you. If perimenopause changed your gut overnight, this one's for you.Andrea Donsky, nutritionist, published menopause researcher, menopause educator, author, and co-founder of wearemorphus.com sits down with nurse practitioner and bestselling author Cynthia Thurlow to unpack the gut-hormone connection nobody warned us about. Cynthia's brand new book, The Menopause Gut (out April 28), is the paradigm-shifting guide to why 94% of perimenopausal women suddenly have digestive issues, and what to actually do about it.What you'll learn:Why you can't digest food properly if you're stressed (and the 4-breath trick that changes it)What the estrobolome is and how it's recycling your estrogen in ways that make bloating worseThe fiber mistake that's making your gut feel worse, not betterWhy your gut suddenly looks more like a man's after menopauseHow PCOS and perimenopause collide (and why it's not "over" when your period stops)The difference between intermittent fasting and "digestive rest" and which one works better in midlifeChapters:0:00 Cynthia's Morocco Story: When Perimenopause Broke Her Gut 2:10 Why Gut Health Gets Worse in Perimenopause and Menopause 6:32 Digestion Starts in the Brain: The Parasympathetic Connection 11:10 Estrogen, Histamine, and Why You Suddenly React to Foods 15:58 Postbiotics 101: Butyrate, Urolithin A, and Short-Chain Fatty Acids 21:30 Fiber, Bloating, and Why You Can't Just Jump to 30 Grams a Day 26:15 The Gut-Bone Connection Nobody Talks About 29:58 Sleep, Stress, and the Cortisol-Constipation Loop 34:42 The Vagus Nerve: Your Gut-Brain Superhighway 39:00 Intermittent Fasting vs Digestive Rest: What Changed Her Mind 42:50 PCOS, Insulin Resistance, and Menopause: The Missing Conversation 46:40 Where to Find Cynthia and The Menopause Gut Book

Fibermaxxing: Both Sides of the Argument   97% of men in the US don't meet their daily fiber requirements. Not most men. 97%. And yet Gen Z is suddenly obsessed with maximizing fiber intake, at the exact same time that colon cancer rates in adults under 50 are rising at 3% per year. That timing isn't a coincidence. In this episode we break down where fibermaxxing came from, what the science actually says, and where the carnivore counter-argument holds up and where it falls apart. What we cover: What fibermaxxing actually is, and why the 30-plants-a-week movement behind it traces back to a 2018 study involving over 10,000 citizen scientists The fiber gap: 97% of men and 90% of women aren't hitting daily targets, so "maxxing" sounds extreme when most people are just trying to close a massive deficit Steph Grasso, the RD with 2M TikTok followers who claimed 2024 as "the year of fiber" and why her comment section is a perfect case study in how people misread their body's response to fiber Why "fiber bloats me" is almost always a transition problem, not a verdict, and the ramp-up approach that fixes it Butyrate: the mechanism most people have never heard of. Fiber feeds bacteria that produce it, and it's the primary fuel source for your colon cells with documented anti-cancer properties The colon cancer data in young adults: people born around 1990 are twice as likely to get colon cancer and four times as likely to get rectal cancer as those born in 1950 The Hadza tribe research: one of the last hunter-gatherer populations on earth, eating roughly 150g of fiber a day, with 40% more gut microbial diversity than Americans The carnivore counter-argument, taken seriously: the IBS and Crohn's evidence is real, and the question of why you'd prioritize something indigestible deserves a real answer Why Gut Reset exists: prebiotics build the foundation before probiotics can take hold, and skipping that step is why most probiotic attempts don't stick The Chris Reed connection: how starting each meal with a fibrous food helped him reverse his diabetes markers, and why it's the simplest application of this science Referenced in this episode: Chris Reed diabetes reversal episode Gut Reset  Prof. Tim Spector / ZOE: zoe.com Steph Grasso: @stephgrassord on TikTok Netflix: Hack Your Health American Gut Project (2018) The takeaway: You don't need to chase 100 grams a day. But if you've been avoiding fiber because it bloats you, you likely quit before your gut had a chance to adapt. Give it four weeks done right, and see what happens.

On this episode of Vitality Radio, Jared dives into three cutting-edge supplements gaining attention in the world of longevity and metabolic health: fisetin, spermidine, and butyrate. These compounds work in complementary ways—supporting the body's natural ability to clear aging cells, promote cellular renewal, and optimize gut-driven metabolic signaling. Jared breaks down how “zombie cells” (senescent cells) contribute to inflammation and aging, how autophagy supports cellular efficiency, and why gut health plays a central role in cravings, blood sugar balance, and GLP-1 activity. He also shares practical insights on dosing strategies, including pulse dosing, and how to determine if these advanced tools may fit into your current wellness routine. If you're looking to better understand the connection between cellular health, metabolism, and gut function, this episode offers a thoughtful, research-informed perspective.Products:Buy Fisetin AND Spermadine, get 20% off the sale price! (limited time)Buy 3 or more bottles of GLP-1 Metabolic Optimizer, get $10 off each bottle! (limited time)RegenerLife Sodium Butyrate Postbiotic PacketsJust Ingredients Probiotic Complex - capsulesViRadChem BinderMagnesium BisglycinateAdditional Information:#627: GLP-1 Explained Part 1: How to Support Metabolism Without Drugs#628: GLP-1 Explained Part 2: The Lifestyle Blueprint for Real Metabolic OptimizationVisit the podcast website here: VitalityRadio.comYou can follow @vitalitynutritionbountiful and @vitalityradio on Instagram, or Vitality Radio and Vitality Nutrition on Facebook. Join us also in the Vitality Radio Podcast Listener Community on Facebook. Shop the products that Jared mentions at vitalitynutrition.com. Let us know your thoughts about this episode using the hashtag #vitalityradio and please rate and review us on Apple Podcasts. Thank you!Just a reminder that this podcast is for educational purposes only. The FDA has not evaluated the podcast. The information is not intended to diagnose, treat, cure, or prevent any disease. The advice given is not intended to replace the advice of your medical professional.

What if your gut has been signaling a problem for your brain for years? That is exactly what the latest science on the gut microbiome and Parkinson's disease is revealing, and it begins with something as overlooked as constipation. If you have ever dismissed a sluggish digestive system as no big deal, this conversation may be the most important one you hear all year.Salad With a Side of Fries host Jenn Trepeck welcomes Martha Carlin, microbiome researcher, founder of The BioCollective and a woman who traded a corporate career for a microscope after her husband was diagnosed with Parkinson's at 44. What she has uncovered about gut bacteria, endotoxin load, the glycocalyx, and neurological decline is both startling and deeply actionable. This is not fear, it is fuel for better choices.What You Will Learn in This Episode:✅ Why chronic constipation is far more than a digestive inconvenience and how waste sitting in the colon produces an endotoxin load now linked to Parkinson's, depression, autism, and diabetes.✅ What the glycocalyx is, why it matters for everything from gut health to cardiovascular function, and how damage to this critical structure can spread throughout the entire body over time.✅ How H. pylori consumes dopamine in the gut, why that interaction may explain why Parkinson's disease medications lose effectiveness, and what the research from Harvard reveals about this connection.✅ The surprising ways that endurance athletics, over-cleaning with quaternary ammonium compounds, and glyphosate-exposed foods all quietly assault the gut microbiome and compound your risk over time.The Salad With a Side of Fries podcast, hosted by Jenn Trepeck, explores real-life wellness and weight-loss topics, debunking myths, misinformation, and flawed science surrounding nutrition and the food industry. Let's dive into wellness and weight loss for real life, including drinking, eating out, and skipping the grocery store.TIMESTAMPS:00:00 Martha Carlin's powerful warning: constipation creates a toxic burden linked to Parkinson's disease and neurological decline05:18 How Martha's husband's Parkinson's disease diagnosis launched her career in gut microbiome research07:08 How specific gut bacteria profiles reveal two distinct types of Parkinson's disease10:02 The concrete stool discovery: how electrolyte imbalance, sodium, and potassium disrupt nerve signaling and drive constipation12:24 Connection between chronic constipation and toxin reabsorption to autism, depression, diabetes, and neurological disease13:17 Glycocalyx: the overlooked protective barrier linking gut health to brain and cardiovascular function21:25 Quaternary ammonium compounds in cleaning products have more than doubled since COVID and are now linked to immune system disruption and Parkinson's disease24:06 Why Parkinson's disease is multifactorial: the glycocalyx as a self-assembled structure that becomes unstable over time29:18 A morning ritual backed by 1912 research: warm water with kosher salt and lemon to support gut health and daily elimination, and the definition of regular elimination33:19 Prebiotics, probiotics, and postbiotics work together across the GI tract, with butyrate as a critical fuel for the glycocalyx37:11 How Sugar Shift probiotics and apple cider vinegar with the mother can help break down glyphosate and support gut microbiome health41:47 Martha's closing message of hope: diet, exercise, gut health, and daily habits can shift the trajectory of Parkinson's diseaseKEY TAKEAWAYS:

Butyrate is a short-chain fatty acid produced by the microbiome—and it plays a foundational role in gut health, inflammation control, immune system regulation, and even brain function. The problem? Most people today are deficient due to poor microbiome health, low fiber tolerance, and chronic gut dysfunction. Steven breaks down how butyrate supports the integrity of the gut lining, fuels colon cells, regulates oxygen levels in the microbiome, and creates an environment where beneficial bacteria can thrive. Without it, even the best diets and supplements may fall short.   TOPICS DISCUSSED: Butyrate: What It Is & Why It Matters Tributerin vs Standard Butyrate Diet Debate (Fiber vs Carnivore vs Vegan) Root Cause vs Symptom-Based Healing Failures of Probiotics & Supplement Industry Nervous System & Environmental Inputs   More from Steven Wright: Website: healthygut.com Instagram: @healthygutco   Leave us a Review: https://www.reversablepod.com/review   Need help with your gut? Visit my website gutsolution.ca to join a program: Get help now   Contact us: reversablepod.com/tips    FIND ME ON SOCIAL MEDIA: Instagram  Facebook  YouTube   

Host: Unique DoctorGuest: Dr. Jason Hawrelak (Microbiome Specialist & Educator)Episode SummaryIn this episode, Unique Doctor sits down with renowned clinician and researcher Dr. Jason Hawrelak to discuss why the modern trend of "carpet-bombing" the gut with antimicrobials like Berberine and Oregano oil may be doing more harm than good. They explore the nuances of Akkermansia, the dangers of hidden chemicals in natural supplements, and how to use fiber and targeted herbs as "snipers" to restore a healthy internal ecosystem.Key Information & HighlightsThe Problem with "Natural" Antimicrobials: Many popular herbal treatments (Berberine, Oregano Oil, Grapefruit Seed Extract) are non-selective. They kill beneficial Bifidobacteria and butyrate-producers, often leading to a "bloom" of pathogens like E. coli and Klebsiella shortly after treatment.The "Sniper" Herb – Pomegranate Husk: Unlike broad-spectrum killers, Pomegranate Husk acts selectively. It inhibits pathogens and fungi while actually encouraging the growth of beneficial microbes.The Oxygen/pH Dynamic: You can suppress pathogens without "killing" them by changing the environment. Pathogens hate acidity and oxygen-free environments. Feeding your gut fiber creates Butyrate, which sucks oxygen out of the gut and lowers the pH to a level pathogens cannot tolerate.Akkermansia Insights: If you are missing Akkermansia muciniphila, current supplements may not "colonize" you permanently. However, red polyphenols (Pomegranate, Dragon Fruit, Cranberry) and prebiotics like Inulin can drastically increase levels if the species is still present.The Probiotic Myth: Probiotics rarely "recolonize" a healthy gut. They are transient travelers that perform specific tasks (e.g., speeding up transit time or producing GABA for anxiety) but usually don't stay forever.Recommended ResourcesThe Corn/Quinoa Test: Eat corn or black quinoa and track how many hours/days it takes to appear in the stool (Optimal is 18–30 hours).Microbiome Testing: Look for Shotgun Metagenomics or 16S DNA testing rather than basic PCR pathogen tests. I like Tiny Health for North America. Code: youregreatDietary Goals: Aim for 40–50g of fiber daily from diverse plant sources.Watch the episode here: https://www.youtube.com/@beanprotocolJoin The Legume Love letter Newsletter here: LOVE LETTERS

Beyond Probiotics: Rebuilding the Gut Microbiome as an Ecosystem with Dr. Oscar Coatzee and Danielle Arnold  and host Dr. Ben Weitz.   [If you enjoy this podcast, please give us a rating and review on Apple Podcasts, so more people will find The Rational Wellness Podcast. Also check out the video version on my WeitzChiro YouTube page.]   Podcast Highlights Rethinking Probiotics: Keystone Anaerobes, Butyrate, and Microbiome Ecosystems with Designs for Health Dr. Ben Weitz introduces the Rational Wellness Podcast episode challenging the assumption that gut issues are solved by adding more traditional probiotics, arguing microbiome repair is an ecosystem and function problem. He interviews Dr. Oscar Cozo and Danielle Arnold of Designs for Health about differences between transient aerobic probiotics (e.g., lactobacillus/bifidobacteria) and keystone anaerobic strains that form the microbiome's foundation, can engraft, drive down gut oxygen, and support cross-feeding. They discuss live, refrigerated delivery for anaerobes; a spore-capable keystone strain (Anaerostipes); and a case study showing improved food allergies, normalization of Akkermansia, increased butyrate-related effects, and reduction of opportunists without antimicrobials. They cover butyrate's roles (tight junctions, mucus, immune regulation, HDAC inhibition), fiber and resistant starch strategies, stool testing (GI-MAP additions for anaerobes and short-chain fatty acids), diet restriction concerns, and practitioner support and case report publishing with Designs for Health. 00:00 Show Intro and Mission 01:00 Probiotics vs Ecosystem Thinking 02:56 Aerobes vs Anaerobes Explained 07:06 Keystone Species and Engraftment 09:18 New Anaerobic Strains and Allergy Research 11:06 Live Shipping and Feeding the Strains 14:03 Case Study Crowding Out Dysbiosis 18:03 Rethinking the Five R Protocol 24:26 Testing and Prebiotic Pairings 26:52 Butyrate and Microbiome Benefits 28:40 Conventional Probiotics Still Matter 35:04 Sponsor Break Apollo Wearable 36:37 Crowding Out Pathogens and Fungi Role 39:58 Archaea and Mucosa 41:21 Mucus Layer and Biofilms 43:11 Feeding Keystone Microbes 44:18 Fiber Targets and Tolerance 46:51 Probiotic as SIBO Option 48:54 Resistant Starch Basics 51:52 Stool Test Dysbiosis Patterns 54:32 Akkermansia and Metabolism 56:44 Histamine Bugs and Enzymes 01:02:26 Gut Healing Nutrients 01:05:34 Diet Diversity and Reintros 01:08:21 Wrap Up and Product Details 01:13:10 Podcast Outro and Clinic Info   Dr. Oscar Coatzee has over 25 years experience in psychology and nutrition and is currently the VP of clinical education and practitioner support at Designs For Health. He has a bachelor's degree in psychology and a PhD in Holistic Nutrition and  Doctorate of Clinical Nutrition. Danielle Arnold is a clinical nutritionist and Functional Medicine practitioner and she serves as a clinical support specialist at Designs for Health, training healthcare providers in test interpretation and patient care. Dr. Ben Weitz is available for Functional Nutrition consultations specializing in Functional Gastrointestinal Disorders like IBS/SIBO and Reflux and also Cardiometabolic Risk Factors like elevated lipids, high blood sugar, and high blood pressure.  Dr. Weitz has also successfully helped many patients with managing their weight and improving their athletic performance, as well as sports chiropractic work by calling his Santa Monica office 310-395-3111.

Fiber has been talked about for decades — but emerging research suggests most of us still don't understand what it actually does, how much we need, or why the modern diet has left us so dramatically short of it.In this episode of The Mind–Gut Conversation, Dr. Mayer is joined by Dr. Matt Amicucci, food scientist and co-founder of OneBio, to discuss the cutting-edge science of dietary fiber and its far-reaching role in gut health, metabolism, and disease prevention.Dr. Amicucci explains how different fiber structures interact with specific microbial communities in the gut to produce short-chain fatty acids like butyrate — and how those molecules influence everything from blood glucose regulation to GLP-1 secretion to long-term mortality risk. He also shares the story behind Glycopedia, the largest dietary fiber database ever built, and how it is being used to develop a new generation of personalized, microbiome-targeted nutrition.They also discuss why 95% of Americans fall short of even the minimum recommended fiber intake, how decades of food processing have systematically stripped fiber from the diet, and what it will take to close that gap.This is a practical, science-driven discussion for anyone interested in nutrition, the gut microbiome, and the future of food.--------------------------------------Connect with Dr. Mayer:Website: https://www.emeranmayer.comInstagram: https://www.instagram.com/emeranmayer/X (Twitter): https://www.twitter.com/emeranmayermdFacebook: https://www.facebook.com/EmeranMayerMD/LinkedIn: https://www.linkedin.com/in/emeranmayer/--------------------------------------Chapters:0:00 - Introduction2:38 - Matt's Origin Story: From Chef to Food Scientist6:43 - Why Fiber Is Having a Moment8:58 - The Fiber Deficit Crisis11:36 - What Decades of Low Fiber Intake Has Done to the Microbiome13:47 - Building Glycopedia: Mapping the World's Fibers19:33 - Why Whole Foods Alone Aren't Enough21:42 - Not All Fiber Is Created Equal25:47 - Introducing GoodVice27:34 - The Health Case for 10 More Grams a Day33:49 - Rethinking Sugar and Fiber Together36:34 - Fiber, Butyrate, and GLP-138:42 - The Future of Personalized Fiber Nutrition40:17 - What's Next for OneBio

The script explains why fiber is critical for gut and metabolic health, focusing on how soluble fiber is fermented in the colon to produce short-chain fatty acids (butyrate, propionate, acetate). It contrasts soluble fiber (forms a gel, lowers LDL by binding bile acids, slows glucose absorption, increases satiety, feeds the microbiome) with insoluble fiber (adds stool bulk, helps constipation). It highlights research showing 10 g/day psyllium husk (Metamucil) is linked to a 10% reduction in all-cause mortality and typically lowers LDL about 7–15%. Butyrate is emphasized as the primary fuel for colonocytes, supporting gut barrier integrity and potentially reducing colon cancer risk, while also affecting mitochondria, inflammation, and the brain. Propionate influences liver cholesterol production and satiety hormones, and acetate provides systemic energy. Practical supplementation "stacks," dosing ranges, food sources, GI side effects, and timing cautions (e.g., separating psyllium from minerals) are discussed.   Metamucil (psyllium husk fiber) — https://www.metamucil.com/   Psyllium husk (soluble fiber) — https://medlineplus.gov/druginfo/meds/a601104.html Psyllium husk (PubMed search) — https://pubmed.ncbi.nlm.nih.gov/?term=psyllium+husk   Soluble fiber (overview) — https://medlineplus.gov/dietaryfiber.html Insoluble fiber (overview) — https://medlineplus.gov/dietaryfiber.html   Inulin (prebiotic fiber) — https://pubmed.ncbi.nlm.nih.gov/?term=inulin+prebiotic+fiber   Acacia fiber / Gum arabic (prebiotic fiber) — https://pubmed.ncbi.nlm.nih.gov/?term=acacia+fiber+gum+arabic+prebiotic   Beta-glucan (oats/barley soluble fiber) — https://pubmed.ncbi.nlm.nih.gov/?term=beta-glucan+oats+LDL   Pectin (soluble fiber) — https://pubmed.ncbi.nlm.nih.gov/?term=pectin+soluble+fiber   Partially hydrolyzed guar gum (PHGG) — https://pubmed.ncbi.nlm.nih.gov/?term=partially+hydrolyzed+guar+gum   Resistant starch / Potato starch — https://pubmed.ncbi.nlm.nih.gov/?term=resistant+starch+potato+starch   Short-chain fatty acids (SCFAs) — https://www.ncbi.nlm.nih.gov/books/NBK557571/   Butyrate (SCFA) — https://pubmed.ncbi.nlm.nih.gov/?term=butyrate+short-chain+fatty+acid+colonocytes   LDL cholesterol (general) — https://medlineplus.gov/cholesterol.html   Magnesium (mineral supplement info) — https://medlineplus.gov/magnesium.html   Show Notes   00:00 Butyrate and Colon Health 00:49 Why Fiber Matters Now 02:28 How Fiber Is Digested 03:45 Soluble vs Insoluble Fiber 06:36 Gel Effect on Blood Sugar 07:36 How Soluble Fiber Lowers LDL 10:19 Short Chain Fatty Acids 101 11:32 Butyrate Deep Dive 16:40 Propionate and Liver Benefits 18:22 Acetate for Energy and Appetite 19:29 Best Fibers to Supplement 21:33 Dosing and Food Sources 24:44 Ideal Fiber Stack and Safety 28:37 Wrap Up and Next Steps   The Hart2Heart podcast is hosted by family physician Dr. Michael Hart, who is dedicated to cutting through the noise and uncovering the most effective strategies for optimizing health, longevity, and peak performance. This podcast dives deep into evidence-based approaches to hormone balance, peptides, sleep optimization, nutrition, psychedelics, supplements, exercise protocols, leveraging sunlight, and de-prescribing pharmaceuticals — using medications only when absolutely necessary. Beyond health science, we explore the intersection of public health and politics, exposing how policy decisions shape our health landscape and what actionable steps people can take to reclaim control over their well-being. Guests range from out-of-the-box thinking physicians such as Dr. Casey Means (author of "Good Energy") and Dr. Roger Sehult (Medcram lectures) to public health experts such as Dr. Jay Bhattacharya (Director of the National Institutes of Health (NIH) and Dr. Marty Mckary  (Commissioner of the Food and Drug Administration (FDA) and high-profile names such as  Zuby and Mark Sisson (Primal Blueprint and Primal Kitchen). If you're ready to take control of your health and performance, this podcast is for you.We cut through the jargon and deliver practical, no-BS advice that you can implement in your daily life, empowering you to make positive changes for your well-being.   Connect with Dr. Mike Hart Instagram: @drmikehart Twitter: @drmikehart Facebook: @drmikehart

Fiber has been talked about for decades — but emerging research suggests most of us still don't understand what it actually does, how much we need, or why the modern diet has left us so dramatically short of it.In this episode of The Mind–Gut Conversation, Dr. Mayer is joined by Dr. Matt Amicucci, food scientist and co-founder of OneBio, to discuss the cutting-edge science of dietary fiber and its far-reaching role in gut health, metabolism, and disease prevention.Dr. Amicucci explains how different fiber structures interact with specific microbial communities in the gut to produce short-chain fatty acids like butyrate — and how those molecules influence everything from blood glucose regulation to GLP-1 secretion to long-term mortality risk. He also shares the story behind Glycopedia, the largest dietary fiber database ever built, and how it is being used to develop a new generation of personalized, microbiome-targeted nutrition.They also discuss why 95% of Americans fall short of even the minimum recommended fiber intake, how decades of food processing have systematically stripped fiber from the diet, and what it will take to close that gap.This is a practical, science-driven discussion for anyone interested in nutrition, the gut microbiome, and the future of food.--------------------------------------Connect with Dr. Mayer:Website: https://www.emeranmayer.comInstagram: https://www.instagram.com/emeranmayer/X (Twitter): https://www.twitter.com/emeranmayermdFacebook: https://www.facebook.com/EmeranMayerMD/LinkedIn: https://www.linkedin.com/in/emeranmayer/--------------------------------------Chapters:0:00 - Introduction2:38 - Matt's Origin Story: From Chef to Food Scientist6:43 - Why Fiber Is Having a Moment8:58 - The Fiber Deficit Crisis11:36 - What Decades of Low Fiber Intake Has Done to the Microbiome13:47 - Building Glycopedia: Mapping the World's Fibers19:33 - Why Whole Foods Alone Aren't Enough21:42 - Not All Fiber Is Created Equal25:47 - Introducing GoodVice27:34 - The Health Case for 10 More Grams a Day33:49 - Rethinking Sugar and Fiber Together36:34 - Fiber, Butyrate, and GLP-138:42 - The Future of Personalized Fiber Nutrition40:17 - What's Next for OneBio

Butyrate is a short-chain fatty acid (SCFA) produced when gut bacteria ferment dietary fiber. It serves as the primary fuel for colon cells, including L-cells that produce GLP-1 When your gut produces enough butyrate, natural GLP-1 secretion works properly, supporting appetite control, insulin sensitivity, and weight regulation This butyrate-driven GLP-1 pathway represents your body's built-in weight management system. My new book, "Weight Loss Cure; Melt Fat Naturally With Your Own GLP-1," provides a step-by-step plan to rebuild butyrate production, restore natural GLP-1 signaling, and correct the root drivers of weight gain Low butyrate production disrupts GLP-1 signaling and contributes to obesity, insulin resistance, and metabolic disease Beyond weight regulation, butyrate also supports gut integrity, immune balance, and protection against chronic disease

Get Dr. Vonda's latest insights on strength, bone health, longevity, and aging with power delivered straight to your inbox. Join her free health & longevity newsletter here: https://www.drvondawright.com/resources/aging-longevity   I've spent years focusing on your external mobility, but I've become obsessed with the world living inside you. We used to think of the gut as just a digestion tube; now we know it's a thriving ecosystem and a metabolic pharmacy that dictates your weight, mood, and longevity. If you're doing "everything right" but still struggling with energy, the issue isn't your willpower, it's your microbiome.   In this episode, I sit down with researcher Dr. Karen Corbin to decode the gut's "black box." We're moving beyond basic digestion to explore how fiber triggers the same satiety hormones as modern weight-loss injections. Stop viewing food as mere calories and start seeing it as fuel for your internal garden. It's time to stop fighting your biology and start partnering with your bacteria to design a resilient future from the inside out. What we cover: - How your gut bacteria produce Butyrate, a "magic" compound that heals the gut and lowers inflammation. - The science of how fiber and resistant starch signal your brain to feel full and satisfied. - Why ultra-processed foods are "too easy" for our bodies to digest, leading to metabolic disaster. - Why "industrial milling" is the hidden enemy of metabolic health, turning even "healthy" grains into rapid glucose spikes by making them too easy to digest. - Why your choices at dinner determine your blood sugar response to breakfast the next morning, proving that your microbiome works on a 12-to-24-hour cycle. - Understanding that because every person's "internal garden" is unique, the same "healthy" food can cause a sugar spike in one person while keeping another perfectly stable. - Exploring the deep connection between the health of your microbiome and the energy-producing engines in your cells that drive your vitality.   About Dr Karen Corbin: Dr. Karen Corbin is a PhD researcher and keynote speaker at the forefront of precision nutrition with Advent Health. She has dedicated her career to decoding the "black box" of the microbiome, revealing how our internal pharmacy dictates metabolic health and longevity.   Connect with Dr Karen Corbin: LinkedIn: linkedin.com/in/karen-corbin-phd-rd-75229111 Website: https://www.geeksthatspeak.com/ Timestamps 00:00 Intro 01:46 Meet Your Microbes: The Colon as a Metabolism 'Show' 05:58 How the Microbiome 'Talks' to You: SCFAs, Bloodstream & the Vagus Nerve 09:28 Feed the Good Guys: Fiber, Mucus Barrier & 'Leaky Gut' Explained 14:23 Aging, Exercise, Antibiotics & Hormones: What Changes in Perimenopause 18:27 Prebiotics vs Probiotics vs Synbiotics: Yogurt, Capsules & What Actually Helps 22:24 Can You Test Your Microbiome? The Limits of Diagnostics & Expensive Probiotics 27:29 Diet Can Remodel Your Gut: The 4 Research-Backed Levers 32:12 Does Food Order Matter? + CGM Lessons on Carbs, Protein, and Spikes 35:48 Practical Breakfast Upgrades: Oats, Flax, Nuts, and Easy Wins 37:00 Calories Aren't One-Size-Fits-All: Microbes, Absorption, and Weight Differences  

What if your gut symptoms aren't about what you're taking, but who you're feeding?Gut change doesn't start with a supplement aisle sweep. It starts with the small but mighty species running your internal ecosystem. In this episode, functional naturopath Dan Sippel joins us to unpack how keystone bacteria shape gut barrier integrity, immune tolerance and metabolic health, and why the right polyphenols, fibres and bile acids can stabilise a volatile gut without triggering flare-ups.We explore short-chain fatty acids, especially butyrate, as the microbiome's currency, influencing inflammation, insulin sensitivity and even brain signaling. Dan shares a laddered strategy for IBS- and SIBO-prone patients: start with low-aggravation polyphenols like pomegranate peel and green tea to lift Akkermansia and Bifidobacterium; introduce partially hydrolysed guar gum as tolerance improves; then progress to resistant starch once the gut lining calms. Along the way, we break down cross-feeding, when direct butyrate makes sense, and why single-strain probiotics only work when you know the strain's job.We also dive into bile acids as the missing link in many stuck cases, including constipation, fat maldigestion, hormone symptoms and perimenopause transitions. You'll learn how dysbiosis disrupts primary-to-secondary bile acid conversion and how to run a practical gut oil change using choleretics, ox bile or TUDCA. Plus, we cover iron repletion without microbiome damage, the role of sleep and melatonin in T-reg signaling, vagal tone support with L-theanine and kava, and a simple daily polyphenol five you can rotate with patients: cacao, blueberries, pomegranate, raw carrot and green tea.If you've cycled through fibres, probiotics and antimicrobials without lasting results, this conversation offers a sequence that sticks. Build the terrain first, protect keystone species, match fibres to the phase, and retest to prove progress as SCFAs rise and inflammation falls. Connect with Dan: The Functional NaturopathShownotes and references are available on the Designs for Health websiteRegister as a Designs for Health Practitioner and discover quality practitioner- only supplements at www.designsforhealth.com.au Follow us on Socials Instagram: Designsforhealthaus Facebook: Designsforhealthaus DISCLAIMER: The Information provided in the Wellness by Designs podcast is for educational purposes only; the information presented is not intended to be used as medical advice; please seek the advice of a qualified healthcare professional if what you have heard here today raises questions or concerns relating to your health

Have you been told that diet doesn't matter for advanced-stage colon cancer? This is false! Learn what to eat and what to avoid if you're faced with a late-stage colon cancer diagnosis, and what you can do to support your recovery. Just so you know, my full line of high-quality supplements is available on Amazon — search Dr. Berg Supplements.Download Dr. Berg's Free Daily Health Routine: https://drbrg.co/45qtO07 Get the Advanced Colon Cancer Diet Plan here: https://drbrg.co/49F11Gt0:00 Introduction: Stage 4 colon cancer1:19 Cancer explained3:33 Stressing cancer 4:31 Where does cancer come from? 6:34 Colon cells8:21 Fasting and colon cancer 9:19 Cancer prevention tips10:04 Rotating diet for colon cancer Cancer is a unique disease and has the following characteristics:1. Heterogeneous2. Sick and living on the edge3. Metabolically inflexible 4. Originates from damaged mitochondria Insulin resistance is one of the most significant contributors to cancer risk. Insulin resistance can lead to metabolic inflexibility. Cancer also migrates to areas of inflammation. Microbiome disruption damages the microbes that protect the body against cancer. Toxicity caused by alcohol, smoking, and pesticides can also increase the risk of cancer.When you combine these risk factors, you significantly increase your risk of developing cancer.Colon cells get their fuel from a compound called butyrate, which is produced when a microbe consumes fiber. Butyrate strengthens the colon's lining, supports its function, and has potent anti-inflammatory properties. Fiber has protective properties against cancer, but if your gut microbiome is compromised, it can make matters worse. The more advanced the cancer you have, the more you'll need to do prolonged fasting. This stresses the cancer cells and deprives them of fuel. The fasting-mimicking diet is also beneficial. If you haven't been diagnosed with cancer, periodic prolonged fasting can help with prevention. High doses of vitamin D3, sun exposure, and oxygen are also protective against cancer. A rotating diet is an incredible tool for cancer prevention. Focus on consuming key nutrients, including vitamin D3, zinc, omega-3 fatty acids, polyphenols, turmeric, cruciferous vegetables, herbs, spices, green tea, and fermented vegetables. Dr. Eric Berg DC Bio:Dr. Berg, age 60, is a chiropractor who specializes in Healthy Ketosis & Intermittent Fasting. He is the Director of Dr. Berg Nutritionals and author of the best-selling book The Healthy Keto Plan. He no longer practices, but focuses on health education through social media.Disclaimer: Dr. Eric Berg received his Doctor of Chiropractic degree from Palmer College of Chiropractic in 1988. His use of “doctor” or “Dr.” in relation to himself solely refers to that degree. Dr. Berg is a licensed chiropractor in Virginia, California, and Louisiana, but he no longer practices chiropractic in any state and does not see patients, so he can focus on educating people as a full-time activity, yet he maintains an active license. This video is for general informational purposes only. It should not be used to self-diagnose, and it is not a substitute for a medical exam, cure, treatment, diagnosis, prescription, or recommendation. It does not create a doctor-patient relationship between Dr. Berg and you. You should not make any change in your health regimen or diet before first consulting a physician and obtaining a medical exam, diagnosis, and recommendation. Always seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition.

Butyrate is a short-chain fatty acid (SCFA) produced by gut bacteria that ferment dietary fiber. It serves as essential fuel for colon cells and maintaining overall systemic health Adequate fiber intake — around 30 grams daily — is crucial for butyrate production. Without it, your body burns stored fat and protein, creating disease-causing byproducts Butyrate strengthens your gut barrier, preventing intestinal permeability that allows harmful substances to enter the bloodstream and trigger autoimmune responses Research shows butyrate improves insulin sensitivity, reduces diabetes risk, lowers bad cholesterol, prevents colorectal cancer, and supports brain health Boost butyrate by eating fiber-rich foods, resistant starches, fermented foods and probiotics, while avoiding processed foods, managing stress, and limiting unnecessary antibiotics

Discover all of the podcasts in our network, search for specific episodes, get the Optimal Living Daily workbook, and learn more at: OLDPodcast.com. Episode 3259: Dr Jenny Brockis explains how increasing dietary fiber, especially from foods like broccoli, can help protect the brain from age-related cognitive decline. By supporting healthy gut bacteria that produce anti-inflammatory compounds like butyrate, a high-fiber diet reduces brain inflammation and promotes long-term mental sharpness. Read along with the original article(s) here: https://www.drjennybrockis.com/2018/11/19/broccoli/ Quotes to ponder: "Choosing to eat a high fiber diet will enable you to maintain a healthy population of those gut bacteria whose job is to keep your brain healthy and wise." "While we like to think our superfood heroes will save the world and us, it's often the unsung heroes that actually make the biggest difference." "One medium apple, banana, pear or orange will provide anywhere from 4-6 grams of dietary fiber." Episode references: Butyrate and brain health research (NIH): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8477775/ Dennis Burkitt and dietary fiber (via Wikipedia): https://en.wikipedia.org/wiki/Dennis_Burkitt Learn more about your ad choices. Visit megaphone.fm/adchoices

Discover all of the podcasts in our network, search for specific episodes, get the Optimal Living Daily workbook, and learn more at: OLDPodcast.com. Episode 3259: Dr Jenny Brockis explains how increasing dietary fiber, especially from foods like broccoli, can help protect the brain from age-related cognitive decline. By supporting healthy gut bacteria that produce anti-inflammatory compounds like butyrate, a high-fiber diet reduces brain inflammation and promotes long-term mental sharpness. Read along with the original article(s) here: https://www.drjennybrockis.com/2018/11/19/broccoli/ Quotes to ponder: "Choosing to eat a high fiber diet will enable you to maintain a healthy population of those gut bacteria whose job is to keep your brain healthy and wise." "While we like to think our superfood heroes will save the world and us, it's often the unsung heroes that actually make the biggest difference." "One medium apple, banana, pear or orange will provide anywhere from 4-6 grams of dietary fiber." Episode references: Butyrate and brain health research (NIH): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8477775/ Dennis Burkitt and dietary fiber (via Wikipedia): https://en.wikipedia.org/wiki/Dennis_Burkitt Learn more about your ad choices. Visit megaphone.fm/adchoices

Butyrate is a short-chain fatty acid (SCFA) produced when gut bacteria ferment dietary fiber. It provides energy for colon cells and offers health benefits beyond basic nutrition Research suggests butyrate helps manage inflammatory bowel disease (IBD) by reducing inflammation, improving symptoms and strengthening gut barrier integrity Laboratory studies show butyrate helps inhibit cancer cell growth and trigger cell death in colorectal cancer cells, with clinical trials exploring its use alongside traditional treatments Butyrate has been shown to improve insulin sensitivity and glucose metabolism in metabolic disorders, while also influencing appetite-regulating hormones Studies show butyrate protects against neurodegenerative diseases by reducing brain inflammation and enhancing neuronal repair and survival

Butyrate is an essential short-chain fatty acid (SCFA) that fuels colon cells, supports gut barrier function and promotes a balanced microbiome. Colon cells rely on butyrate for up to 80% of their energy needs, helping maintain normal gut function and a healthy intestinal lining Your gut bacteria produce butyrate by fermenting fiber from whole foods such as fruits, vegetables, legumes and whole grains Butyrate supports gut barrier integrity by regulating tight-junction proteins and contributing to mucus production, which protects the colon wall Diet and lifestyle significantly impact butyrate production — a high-fiber diet, exercise, hydration, sleep and avoiding processed fats all support SCFA production Common misconceptions about butyrate include the idea that fiber supplements alone suffice — whole foods provide a wider variety of fiber, nutrients and benefits. If gut health is compromised, gradual fiber introduction is key — eliminating gut-damaging factors first allows for better microbial balance and butyrate production

Butyrate, produced by gut bacteria when they ferment dietary fiber, acts as a signaling molecule in the gut-brain axis, influencing stress, pain tolerance, immunity, and brain health Through multiple mechanisms, including specific enzyme inhibition and NF-κB pathway regulation, butyrate reduces neuroinflammation and protects against neurodegenerative conditions like Alzheimer's and Parkinson's disease Butyrate influences key neurotransmitters including GABA, serotonin, and dopamine, while also increasing brain-derived neurotrophic factor (BDNF), which supports neuronal growth and cognitive function The vagus nerve serves as a communication highway between the gut and the brain, transmitting signals about butyrate levels that affect mood regulation, stress response, and immune function Optimizing gut health through dietary fiber and homemade fermented foods helps promote butyrate production and maintain a healthy gut-brain connection

Avoidant restrictive food intake disorder (ARFID) is an eating disorder where people severely restrict food due to fear, sensory sensitivities, or low interest — not body image concerns — causing significant health and social problems Unlike normal picky eating, ARFID involves intense distress, extremely narrow food choices, nutritional deficiencies, weight loss, and serious disruption to daily life and social activities Prevalence ranges from 0.35% to 6.4% depending on region, primarily affecting children and teens, with average diagnosis at age 11 and higher male representation than other disorders Treatment approaches include parental control strategies, cognitive behavioral therapy, family-based treatment, food therapy, and sequential oral sensory methods to gradually reduce food-related fear and anxiety A specialized protocol combining psychology, hypnosis, and neuro-linguistic programming shows 90% success for adults and 65% for children, often achieved in single session

Butyrate, a short-chain fatty acid produced by gut bacteria that ferment dietary fiber, helps improve metabolic health by enhancing insulin function, regulating glucose levels and supporting healthy body composition Unlike most cells that use glucose, colonocytes (the epithelial cells that line your colon) prefer butyrate for energy, converting 70% to 80% through beta-oxidation to maintain gut barrier health Promoting butyrate production through fiber intake is beneficial, but only if your gut is healthy. If your gut is compromised, starting with dextrose water before transitioning to whole foods is recommended Lifestyle factors significantly impact butyrate production, with chronic stress, smoking, excessive drinking and antibiotic overuse reducing beneficial gut bacteria and SCFA production Excessive linoleic acid consumption, common in processed foods and vegetable oils, reduce beneficial gut bacteria, negatively affecting gut and metabolic health

In today's episode, we had the pleasure of speaking with Pooja M. Phull, MD, a hematologist/oncologist at the John Theurer Cancer Center at Hackensack University Medical Center in New Jersey, about emerging insights into the gut microbiome and its clinical relevance in multiple myeloma. Dr Phull discussed how microbial composition—particularly the presence of butyrate-producing bacteria—may influence therapeutic responsiveness, sustained minimal residual disease negativity, and long-term outcomes for patients undergoing autologous stem cell transplantation. In our exclusive interview, Dr Phull reviewed findings from a translational study that longitudinally profiled the fecal microbiome of patients with newly diagnosed myeloma, highlighting the significant post-transplant depletion of beneficial short-chain, fatty acid–producing organisms and its association with inferior progression-free survival. She also outlined supportive laboratory and in vivo data demonstrating the antitumor effects of butyrate and discussed how microbiome profiling may serve as both a predictive biomarker and a potential therapeutic target. Additionally, Dr Phull explored how dietary patterns, lifestyle factors, and antibiotic stewardship may contribute to preserving gut microbial health, and she emphasized the growing need for prospective studies to clarify how these interventions could enhance treatment outcomes for patients with active myeloma and precursor conditions such as monoclonal gammopathy of undetermined significance and smoldering myeloma.

Butyrate, a short-chain fatty acid produced when gut bacteria ferment dietary fiber, serves as both an energy source for colon cells and an important signaling molecule for immune regulation By inhibiting histone deacetylases (HDAC) and suppressing the NF-κB pathway, butyrate acts as a powerful anti-inflammatory agent, helping prevent chronic inflammation that contributes to various diseases Butyrate promotes regulatory T cell development while modulating other immune cells, helping maintain immune tolerance and preventing autoimmune responses while supporting balanced immune function Butyrate plays a significant role in managing chronic diseases like IBD, multiple sclerosis and Type 2 diabetes by reducing inflammation and supporting gut barrier function Emerging research suggests that butyrate influences brain health by modulating the gut-brain axis; it reduces neuroinflammation and supports cognitive function, and plays a supporting role in the prevention of neurological disorders like Alzheimer's disease and depression

Broadcast from KSQD, Santa Cruz on 12-11-2025: Dr. Dawn presents colleague Dr. Paul Godin's essay on why US healthcare fails as a market system . She explains that healthcare violates every assumption of functional markets: patients can't compare options during emergencies, information asymmetry prevents informed decisions, demand is inelastic when one has an urgent medical issue, and trust is essential to medicine and in direct conflict with profit incentives. Since 1988's Knox-Keen Act allowed for-profit healthcare, private equity has acquired and stripped hospitals, while administrative costs consume enormous resources fighting over payments rather than providing care. She contrasts this with European models like Switzerland and Germany where everyone must participate, insurers must accept all patients, and profit on basic coverage is limited. She celebrates a vaccination success story: HPV vaccines have reduced cervical cancer by 50% over 30 years. The American Cancer Society now endorses self-collected vaginal samples for HPV screening, with an FDA-approved at-home kit from Teal Health allowing women to skip speculums and traditional Pap smears. Current guidelines recommend screening starting at age 25, with testing every five years after a negative result. Dr. Dawn issues a health alert about multiple hospitalizations in Santa Cruz County from foraged wild mushrooms identified incorrectly by phone apps. She describes cholinergic toxicity symptoms: sweating, excessive salivation, pinpoint pupils, and abdominal cramping—signs requiring immediate emergency care rather than waiting it out. She offers follow-up vaccine advice: "go in wet, then sweat." Hydrate before vaccination, then take a hot Epsom salt bath until sweat runs off your face. This helps eliminate adjuvants that cause post-vaccine fatigue and aches, which are often misinterpreted as catching illness from the vaccine itself. Dr. Dawn expresses alarm that Kennedy's reconstituted ACIP nearly voted to eliminate hepatitis B vaccination at birth. She notes infants exposed to infected mothers have 99% infection rates, with half becoming chronically infected and half of those developing terminal cirrhosis or cancer. Testing pregnant women misses infections acquired during pregnancy, and 12-16% of delivering women have no test records. Major insurers have committed to covering birth vaccination through 2026 despite the panel's actions. She offers holiday microbiome advice from researcher Karen Corbin: increase fiber intake through steel-cut oats, whole grain breads like Dave's Killer Bread, beans, apples, and alternative pastas made from lentils or garbanzo beans. Cooking potatoes ahead and reheating creates resistant starch that feeds beneficial gut bacteria, reduces inflammation, and even stimulates natural GLP-1 production. Dr. Dawn reviews research proving health insurance saves lives. When the ACA's Medicaid expansion became optional by state, researchers could compare outcomes, finding 8% lower mortality and 19,000 fewer deaths in expansion states over four years. An accidental IRS experiment—sending insurance enrollment letters to only 85% of penalty payers—showed significantly lower mortality among those who subsequently got insured. Studies of gunshot and auto accident victims found uninsured patients died more often despite receiving identical emergency treatment. She concludes with surprising cancer symptoms: chest pain specifically triggered by alcohol consumption may indicate Hodgkin's lymphoma, as vasodilation activates inflammatory chemicals in affected lymph nodes. Fractures from minimal trauma in people without osteoporosis warrant investigation, as 5% of cancers involve bone. Elevated calcium levels double cancer diagnosis risk in the following year and should prompt follow-up testing.

In this episode, we dive deep into the holy trinity of gut repair: Akkermansia muciniphila, butyrate, and choline... and why people with food sensitivities, allergies, histamine reactions, IBS, constipation, autoimmune issues, or chronic inflammation cannot heal without addressing this trio. You'll learn:-Why Akkermansia is the #1 microbe linked to a strong gut lining-How butyrate fuels colon cells, lowers inflammation, and regulates immunity-Why choline deficiency is one of the MOST overlooked causes of food reactions-Foods, supplements, and lifestyle steps to rebuild your mucus layer-What destroys Akkermansia (and how to fix it naturally)-The REAL science behind how the gut wall heals Join my FREE gut reset MASTERCLASS: https://mailchi.mp/holisticspring.com/reset-your-gut-workshopEquip Foods Grass-fed beef protein - Code: MARLAWant to work with me? email me to health@holisticspring.com

Exploring the Microbiome and Longevity with Dr. Ross Pelton, Director of Science & Education for Essential Formulas Inc., which specializes in premium probiotic products. He's known as the Natural Pharmacist. He details the pivotal role of the gut in chronic disease, referencing the ancient insights of Hippocrates, and explores the concept of postbiotics. The conversation touches on the influence of gut health on various organ systems, the importance of diversity in the gut microbiome, and how lifestyle choices like diet, exercise, and sleep contribute to healthy aging. They also tackle cutting-edge topics such as the implications of GLP-1 medications, anabolic resistance, and the potential benefits of rapamycin for longevity.

Dr. Hoffman continues his conversation with Dr. Ross Pelton, Director of Science & Education for Essential Formulas Inc., which specializes in premium probiotic products. He's known as the Natural Pharmacist. 

Butyrate is a short-chain fatty acid produced by gut bacteria when they ferment fiber, serving as the primary energy source for colon cells and maintaining gut barrier strength Healthy butyrate levels support weight management, blood sugar control, and brain health, with studies linking butyrate-producing bacteria to reduced Alzheimer's risk and lower cancer risk A diverse diet rich in various fiber sources, including fruits, vegetables, and whole grains, promotes butyrate production, but increases should be gradual if your gut health is compromised The gut barrier weakens with insufficient butyrate, allowing undigested food, bacteria, and toxins to enter your bloodstream, triggering systemic inflammation and widespread health problems Gradually increasing fiber intake and reducing mitochondrial toxins for increased cellular energy supports gut health and beneficial gut microbes, enhancing butyrate production and overall health

The microbiome continues to be viewed as a cornerstone of health, whether we are discussing the gastrointestinal tract, cardiovascular risk, immune dysfunction, and even cognitive health. One major contributions of the microbiome to our global health is in the production of short-chain fatty acids. Primary among these products is a compound known as n-butyrate. N-butyrate has profound roles, not only in our gut, but throughout our entire body. What are all the impacts of n-butyrate, and how do we foster an adequate supply of it? These are but some of the questions we discuss on today’s Lab Report. In this episode, we continue our spree on the importance of gut health. We cover food sources that are important for microbiome health, particularly for fermentation of short-chain fatty acids. We also cover how butyrate impacts the gut, the immune system, and much more. With all the profound roles of n-butyrate, it begs the question: is it the greatest of all the things made by our microbiome? Today on The Lab Report: 5:30 Gut microbiome production of SCFA’s (short-chain fatty acids) 6:30 Food sources of n-butyrate 8:00 Let’s Google It: The entomology of ‘butyrate’ 9:00 Butyrogenic species: What bacteria produce butyrate? 10:45 How butyrate is used throughout the body 13:00 Logical Speculation: n-butyrate, autoimmunity, and fiber 15:45 The gut-brain axis and appetite are influenced by butyrate 20:30 Skeletal muscle also responds to butyrate 23:30 Foods to eat to promote butyrate 26:00 N-Butyrate supplementation: mixed studies? Additional Resources: GI Effects Stool Profile Microbiomix Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: podcast@gdx.net. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.See omnystudio.com/listener for privacy information.

*JOIN THE PHYSIONIC INSIDERS [PREMIUM CONTENT]*Join the Physionic Insiders: https://bit.ly/PhysionicInsiders2 *HEALTH AUTONOMY [COURSE]*Learn to Analyze & Apply Studies for Yourself: https://bit.ly/healthautonomy*JOIN THE COMMUNITY*Join my Community [It's Free!]: https://bit.ly/PhysionicCommunity2*EMAIL LIST*1-2 Weekly Email of Value [It's Free!]: http://bit.ly/2AXIzK6*HIRE ME FOR CONSULTING:* Consulting: https://bit.ly/3dmUl2H 0:00 - Introduction4:02 - Collagen for Skin 'Debunked'36:30 - Ketones track with Liver Disease52:15 - Butyrate and Cancer1:25:50 - Seed Oils - Harmful?1:59:55 - Ineffective Creatine2:17:17 - Non-Nutritive Sweeteners and Cognitive Decline2:42:39 - Housekeeping, Updates, Hangout

In Episode #184 of the PricePlow Podcast, Mike and Ben welcome back Ed Dosz, VP of Science Innovation at NutriScience Innovations, for a comprehensive exploration of ButyraGen, a revolutionary ingredient that generates butyrate directly in the small intestine. With butyrate serving as the primary fuel for colon cells while playing crucial roles in gut barrier function, immune modulation, and the gut-brain axis, Ed explains why this short-chain fatty acid has become one of the most important yet overlooked compounds in modern nutrition. Ed Dosz Returns to Discuss ButyraGen: Solving the Modern Butyrate Crisis The conversation tackles a fundamental problem facing modern gut health: the average American consumes only half the fiber needed for adequate butyrate production, and traditional prebiotics work only if you have the right gut bacteria. Ed details how ButyraGen's unique tributyrin-based formulation bypasses these limitations entirely through enzymatic action, delivering consistent butyrate generation regardless of microbiome status, age, or dietary habits. Beyond the science of butyrate delivery, Ed shares insights from two published clinical studies demonstrating ButyraGen's real-world benefits, including significant reductions in belly pain and improvements in digestive quality of life. The discussion reveals particularly strong benefits for women and postmenopausal individuals, explores the fascinating gut-brain connection, and examines ButyraGen's potential applications in metabolic health, GLP-1 support, and beyond. This episode provides a comprehensive look at why direct butyrate generation represents the next evolution in digestive health supplementation. Subscribe to the PricePlow Podcast for more conversations with ingredient scientists and industry innovators! [[INSERT SMALL LINK]] Video: Ed Dosz Explains NutriScience's ButyraGen - Direct Butyrate Generation https://www.youtube.com/watch?v=OnXrruuWyBE Detailed Show Notes: The Science and Clinical Benefits of ButyraGen (0:00) – Introduction and Reconnecting with Ed Dosz (1:30) – Why Butyrate Matters: The Gut's Primary Fuel (5:00) – The Modern Butyrate Deficit Crisis (9:15) – Why Traditional Prebiotics Fall Short (13:30) – Introducing ButyraGen: Direct Butyrate Generation (18:45) – Dosing Efficiency: Small Dose, Massive Impact (23:00) – Clinical Evidence: Two Published Human Studies (28:15) – Women's Health: The Standout Clinical Finding (33:30) – The Gut-Brain Axis and Future Research Directions (38:45) – Metabolic Health and GLP-1 Connections (43:15) – Practical Applications and Product Formulations (48:30) – Quality Matters: Not All Tributyrin Is Created Equal (53:00) – Stacking Strategies and Combination Recommendations (57:45) – Safety, Tolerability, and Long-Term Use (1:02:15) – Ed's Vision for the Future of Gut Health (1:06:30) – Closing Thoughts and Contact Information Where to Follow Ed Dosz and Learn More About ButyraGen NutriScience Innovations: NutriScienceUSA.com NutriScience on LinkedIn: LinkedIn.com/company/nutriscience-innovations-llc/ Ed Dosz on LinkedIn: LinkedIn.com/in/edward-dosz/ ButyraGen Breakdow... Read more on the PricePlow Blog

In this episode, we'll delve into the world of butyrate, exploring what it is, why it's important, and how it can benefit your colon health. We'll also discuss whether butyrate supplements are effective and if they can help improve your colon health. Join us to learn more about this vital nutrient and how it can help protect your colon.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Dr. Sean Gibbons joins Dr. Buck Joffrey to discuss the complexities of the gut microbiome, its evolution, and its significant role in health and longevity. He explains how our microbiome is established at birth, how it changes throughout life, and the impact of diet and lifestyle on its composition. The discussion also covers the challenges of modifying the microbiome, the potential of precision nutrition, and the emerging field of fecal transplants. Dr. Gibbons emphasizes the importance of butyrate, a beneficial short-chain fatty acid produced by gut bacteria, and the future of microbiome research in developing targeted interventions for health improvement. Learn more about Dr. Sean Gibbons: https://isbscience.org/people/sean-gibbons-phd/?tab=biography - Download Dr. Buck Joffrey's FREE ebook, Living Longer for Busy People: https://ru01tne2.pages.infusionsoft.net/?affiliate=0 Book a FREE longevity coaching consultation with Dr. Buck Joffrey: https://coaching.longevityroadmap.com/

Send us a textDr. Brandon Crawford and bestselling author Dr. Steven Gundry challenge the medical myth of a mind-body separation, arguing the gut may be our "first brain." They dive into how gut health, influenced by biofilms, light, and microbial diversity, directly impacts brain fog, mood, and chronic disease. Learn practical steps to heal your gut ecosystem, boost butyrate, and reframe your approach to wellness from the inside out.ProductsThe Gut-Brain Paradox: https://amzn.to/3U08ZTlSupplements: Use PODCAST20 at Checkout for 20% off your first order at GundryMD.comGundry Health Tele-medicine: gundryhealth.comResources MentionedBooks by Dr. Gundry:The Plant Paradox (2017)The Longevity ParadoxGut Check (latest)The Energy ParadoxUnlocking the Keto CodeClinical Tools & Tests:Vibrant Wellness “Gut Zoomer” stool test + Anti‑zonulin, Anti‑actin, Anti‑LPS leaky gut blood panel Gundry HealthSupplement Protocols & Products:Gundry MD 24‑strain probiotic (research-based formulation)Gundry MD Bio Complete 3 (prebiotic + probiotic + postbiotic blend)Specific Concepts & Tools Mentioned:Vitamin D3 (aggressive dosing up to 10,000–40,000 IU/day with K2) to seal gut and suppress autoimmunity.Fermented foods (kimchi, sauerkraut, kefir, coffee, tea, wine, dark chocolate) as critical fiber + microbial substrates.Light therapy (red / near‑infrared photobiomodulation) to influence gut microbiome and mitochondria.Products 528 Innovations Lasers NeuroSolution Full Spectrum CBD NeuroSolution Broad Spectrum CBD NeuroSolution StimPod STEMREGEN® Learn MoreFor more information, resources, and podcast episodes, visit https://tinyurl.com/3ppwdfpm

Ever wonder which probiotic strains do what? We've got just the experts. This week, we're joined by Dr. Joseph Gretzula and Christina O'Connor, RD as they dive into the deep world of probiotics. Listen in as they discuss the skin microbiome, different bacterial strains, and just why not all probiotics are created equal. Each Thursday, join Dr. Raja and Dr. Hadar, board-certified dermatologists, as they share the latest evidence-based research in integrative dermatology. For access to CE/CME courses, become a member at LearnSkin.com.   Joseph C. Gretzula, DO FAAD is a Board-Certified Dermatologist serving South Florida for over 30 years. He received his training in Dermatology at the Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery at the University of Miami in Miami, Florida. He is board-certified in Dermatology and is a Diplomat of the American Board of Dermatology. Christina is a registered dietitian and the Senior Healthcare Account Manager at Pendulum Therapeutics. She received her bachelor of science at James Madison University and completed her Dietetic Internship through the Virginia Department of Health.   Sponsored by: Pendulum Visit Pendulum website for more information. 

Dr. Inna Melamed is a pharmacist and functional medicine practitioner who specializes in Crohn's and colitis, hormonal imbalances, chronic inflammation, and digestive dysfunction.  She is the founder of Digestive Reset, the author of two books, Crohn's and Colitis Fix and Digestive Reset, and a frequent contributor to professional education platforms.   In this episode of Conversations for Health, we talk about Dr. Inna's professional and personal journey and her dive deep into inflammatory bowel disease. She highlights the strategies that work best for her patients, including supplements and dietary changes, as well as lifestyle changes and stress reduction techniques. As a former pharmacist, she offers insights into the role of the pharmacist in therapeutic duplication and the supplements that every patient should take first.  She highlights notable patterns in stool testing, offers glutamine recommendations to reduce inflammation and strengthen the immune system, and shares encouraging strategies to help practitioners restore their patient's hormone balance by focusing on the gut.   I'm your host, Evelyne Lambrecht, thank you for designing a well world with us.   Episode Resources: Dr. Inna Melamed: https://digestivereset.com/ Dr. Melamed's Courses: https://melamedinstitute.health/ Design for Health Resources: Designs for Health - https://www.designsforhealth.com/ Designs for Health Practitioner Exclusive Drug Nutrient Depletion and Interaction Checker - https://www.designsforhealth.com/drug-nutrient-interaction/ Visit the Designs for Health Research and Education Library which houses medical journals, protocols, webinars, and our blog. https://www.designsforhealth.com/research-and-education/education The Designs for Health Podcast is produced in partnership with Podfly Productions. Chapters: 00:00 Intro. 01:55 Dr. Inna is lit up knowing that her clients are being de-prescribed medications. 2:18 Dr. Inna's personal and professional journey as a pharmacist before becoming a Crohn's and colitis specialist. 6:24 Dr. Inna's approach to her typical patient with Crohn's or colitis. 10:21 The role of the pharmacist in therapeutic duplication. 14:17 What Dr. Inna would do differently if she went back to the pharmacist setting. 16:20 Labs markers, genetic testing, serum markers and stool tests, including fecal calprotectin numbers. 21:24 The importance of food sensitivity testing. 22:29 Notable patterns in stool testing and the benefits of Akkermansia. 27:17 Three basic supplements for nearly all clients, and insights into bitters and digestive enzymes. 32:28 Glutamine recommendations to reduce inflammation and strengthen the immune system. 34:04 Butyrate and other supplements that bring great wins to Crohn's and colitis patients. 38:11 Dietary habits that predispose people to developing Crohn's and colitis. 41:23 Hormone correlations that are common in Dr. Inna's clients. 45:40 What every practitioner needs to know about biologics. 48:22 Restoring hormone balance by focusing on the gut. 49:25 Dr. Inna's favorite supplements, favorite health practices, and her changed view on SIBO testing.

It's always a party when gut health power duo Tina Anderson and Kiran Krishnan from Just Thrive return to the show. In this episode, we explore how true wellness starts in the microbiome—and why fixing your gut could be the key to everything from mental health to metabolic resilience. Kiran breaks down the science behind the gut-brain connection, explaining how neurotransmitters, hormones, and even your stress response are impacted by what's happening in your digestive tract.We also tackle the biggest threats to your microbiome—from antibiotics to glyphosate—and why even “healthy” habits like hand sanitizer and over-cleaning might be backfiring. Plus, Tina and Kiran share practical, affordable lifestyle upgrades that don't require fancy biohacking gadgets or pricey supplements. Whether it's intermittent fasting, getting dirty in the garden, or walking with intention, these tips help build resilience from the inside out.If you've ever wondered how your bacteria might be running the show—or want simple strategies to support your gut without breaking the bank—this one's for you. Visit lukestorey.com/justthrive and use code LUKE for 20% off.DISCLAIMER: This podcast is for educational purposes only and not intended for diagnosing or treating illnesses. The hosts disclaim responsibility for any adverse effects from using the information presented. Consult your healthcare provider before using referenced products. This podcast may include paid endorsements.THIS SHOW IS BROUGHT TO YOU BY: LIMITLESS LIVING MD | Book your free consultation today at limitlesslivingmd.com/luke and use code LUKE for 12% off your first order.MAGNESIUM BREAKTHROUGH | You can use the code LUKE10 for 10% off at bioptimizers.com/luke.BEAM MINERALS | Use code LUKE for 20% off your order at beamminerals.com. QUANTUM UPGRADE | Get a 15-day free trial with code LUKE15 at lukestorey.com/quantumupgrade.MORE ABOUT THIS EPISODE:(00:00:00) Raising Awareness: The Real Win in the Health Revolution(00:08:26) Free Health Hacks That Actually Work(00:21:37) Gut-Brain Science: How Your Microbiome Impacts Anxiety, Stress, & Mood(00:39:46) Why Most Probiotics Fail—and the Microbial Key to Brain Development(00:51:55) Hidden Gut Killers: Antibiotics, Sanitizers, & the Truth About “Rotating” Probiotics(01:10:28) Prebiotics, Butyrate, & Bitters: What Your Gut Actually Needs(01:27:00) Reactivating Your Body's Built-In Digestive CodeResources:• Website: justthrivehealth.com• Instagram: instagram.com/justthrivehealth• Facebook: facebook.com/justthrivehealth• X: x.com/JustThriveHlth• TikTok:

Story at-a-glance Butyrate, produced by gut bacteria when they ferment dietary fiber, acts as a signaling molecule in the gut-brain axis, influencing stress, pain tolerance, immunity and brain health Through multiple mechanisms, including specific enzyme inhibition and NF-κB pathway regulation, butyrate reduces neuroinflammation and protects against neurodegenerative conditions like Alzheimer's and Parkinson's disease Butyrate influences key neurotransmitters including GABA, serotonin and dopamine, while also increasing brain-derived neurotrophic factor (BDNF), which supports neuronal growth and cognitive function The vagus nerve serves as a communication highway between the gut and the brain, transmitting signals about butyrate levels that affect mood regulation, stress response and immune function Optimizing gut health through dietary fiber and homemade fermented foods helps promote butyrate production and maintain a healthy gut-brain connection

Episode Highlights With StevenHow he was a histamine denier and what he found out that changed everythingThe equation of this… histamine isn't a bad thing. You don't want too much or too littleHistamine must be balanced with an enzyme called DAO. When it gets out of balance, we can have symptoms.Signs and symptoms of histamine intolerance and how they overlap with seasonal allergies and stressYeast and histamine connection Histamine and autoimmune connection and how they overlap. The links with genetics here as well.With histamine intolerance, even some healthy foods can temporarily be problematic The problem with leftovers if you have histamine issues Problems occur when we make too much histamine or don't break it down with DAOHow he recovered completely from seasonal allergies and helped his wife do this as wellDAO can help with carsickness in kids as well Butyrate is the key molecule for the gut and what we're learning about this, as well as how it might be more important than probiotics for gut health Butyrate is not something we produce Enzymes can be more helpful for gut health than probiotics, and it's a both and equation We actually do not want a “strong” immune system, we want a balanced immune systemWhat parabiotics are and how they uniquely affect the body and immune systemResources MentionedHistaHarmony supplementHoloImmune

Story at-a-glance Butyrate is a crucial short-chain fatty acid (SCFA) that fuels colon cells, supports gut barrier function, and promotes a balanced microbiome. Colon cells rely on butyrate for up to 80% of their energy needs, helping maintain normal gut function and a healthy intestinal lining Your gut bacteria produce butyrate by fermenting fiber from whole foods such as fruits, vegetables, legumes and whole grains Butyrate supports gut barrier integrity by regulating tight-junction proteins and contributing to mucus production, which protects the colon wall Diet and lifestyle significantly impact butyrate production — a high-fiber diet, exercise, hydration, sleep and avoiding processed fats all support SCFA production Common misconceptions about butyrate include the idea that fiber supplements alone suffice — whole foods provide a wider variety of fiber, nutrients and benefits. If gut health is compromised, gradual fiber introduction is key — eliminating gut-damaging factors first allows for better microbial balance and butyrate production