Podcasts about functional status

Palmitoylethanolamide (PEA) is a naturally occurring endocannabinoid-like lipid mediator naturally found in many plants. PEA is analgesic, immunomodulatory, neuroprotective, antipyretic, antiepileptic, anti-inflammatory, anticonvulsant, antibacterial and antiviral. PEA also increases endocannabinoids and it down regulates mast cell activation.  PEA can improve immune system function without increasing inflammation. PEA also regulates fatty acid metabolism, reduces oxidation of fats, and inhibits excessive nitric oxide. PEA may contribute to enhanced muscle recovery and improved cognition, mood and sleep. PEA may be indicated for anti-aging, immunoenhancement, brain health, allergies, and joint health. These properties make PEA a perfect compound for managing the difficult symptoms of Long COVID. Studies on PEA and Long COVID A recent study entitled, “The Use of Palmitoylethanolamide in the Treatment of Long COVID: A Real-Life Retrospective Cohort Study” looked at the potential benefits of PEA for Long COVID symptoms. Some of the most common Long COVID symptoms include fatigue, brain fog, headache, exercise intolerance, trouble breathing, memory lapse, anosmia, dysgeusia, depression, anxiety, psychosis, nervous asthenia, PTSD, insomnia, delirium and anhedonia. How was the study done? 33 (10 male and 23 female) patients were given 600 mg PEA twice a day for 3 months. All patients were administered the post-COVID-19 Functional Status (PCFS) scale, to assess meaningful function, before (T0) and at the end of the treatment (T1). None of the patients had any side effects from the PEA. Study results All the patients experienced improvement in their Long COVID symptoms as measured by the Post-COVID-19 Functional Status scale. PEA, Luteolin, and Long COVID Studies The combination of PEA and Luteolin has been studied extensively, with multiple published papers showing the synergistic benefits of these two compounds. PEA and luteolin have been shown to reduce neuroinflammation by modulating microglia and reducing reactive oxygen species (ROS). Luteolin is a flavonoid, specifically a flavone, found naturally in fruits, vegetables, and herbs such as celery, parsley, lettuce, spinach, peppers, broccoli, cabbage, carrots, onions (leaves), and apples (skins). Luteolin is similar in structure to quercetin, but luteolin is more potent and is sometimes referred to as a “supercharged” quercetin. Luteolin has the following properties: Anti-inflammatory Anti-neurodegenerative (neuroprotective) Mast cell stabilizer Antioxidant Anticancer Antiallergy Antihypertensive Antiviral Antidiabetic Another study entitled, “What Is the Role of Palmitoylethanolamide Co-Ultramicronized with Luteolin on the Symptomatology Reported by Patients Suffering from Long COVID? A Retrospective Analysis Performed by a Group of General Practitioners in a Real-Life Setting” looked at the medical charts of 49 patients with Long COVID who were treated by one of nine doctors in Rome, Italy. The patients were treated with 700 mg of PEA and 70 mg of luteolin twice a day for 90 days. No side effects were reported during treatment, nor any drug interactions with their medications. The authors conclude, “Supplementation with PEALUT (PEA and Luteolin) helped to improve all patient-reported symptoms, especially pain, anxiety and depression, fatigue, brain fog, anosmia and dysgeusia, leading to an overall improvement in patients' health status.” PEA and luteolin have been found to be effective for post-COVID loss of smell (anosmia) and memory loss. The first study entitled, “Ultramicronized Palmitoylethanolamide and Luteolin Supplement Combined with Olfactory Training to Treat Post-COVID-19 Olfactory Impairment: A Multi-Center Double-Blinded Randomized Placebo- Controlled Clinical Trial” was done for 90 days on subjects who took 700 mg of PEA and 70 mg of luteolin once a day combined with olfac...

Fagfellevurdering er en essensiell del av vitenskapelig kvalitetssikring, men hvem er fagfellevurdererne? I to nye studier har forskerne undersøkt behandling av henholdsvis kronisk og akutt subduralt hematom. JAMA har publisert en originalartikkel om erfaringene gjort ved evakuering av pasienter med tog fra totalt elleve byer i Ukraina. Statiner er fortsatt førstevalget for lipidsenkende medikamentell behandling, men er bempedoinsyre et godt alternativ for de pasientene som tåler statiner dårlig? Skandalekirurgen Paolo Macchiarini har nylig blitt dømt til 30 måneders fengsel, og Karolinska sjukhuset har blitt omtalt som sentrum for «forskningsetikkens Tsjernobyl». I to nylige studier publisert som preprintartikler – altså ennå ikke fagfellevurdert – har man klart å dyrke frem syntetiske humane embryoer helt opp til over to ukers alder, direkte fra stamceller. Islandske forskere har funnet en genvariant som påvirker stemmens toneleie. Sjefredaktør Are Brean forteller om dette og mer i ukens episode av Stetoskopet. Stetoskopet tar nå sommerferie og er tilbake i august. Vi høres! Tilbakemeldinger kan sendes til stetoskopet@tidsskriftet.no. Stetoskopet produseres av Synne Muggerud Sørensen, Are Brean og Julie Didriksen ved Tidsskrift for Den norske legeforening. Ansvarlig redaktør er Are Brean. Jingle og lydteknikk: Håkon Braaten / Moderne media Coverillustrasjon: Stephen Lee Artikler nevnt: Analysis of peer reviewers' response to invitations by gender and geographical region: cohort study of manuscripts reviewed at 21 biomedical journals before and during covid-19 pandemicAssociation of Functional Status, Cognition, Social Support, and Geriatric Syndrome With Admission From the Emergency Department Dexamethasone versus Surgery for Chronic Subdural Hematoma Decompressive Craniectomy versus Craniotomy for Acute Subdural Hematoma Traumatic Acute Subdural Hematoma — Should the Bone Flap Be Removed or Replaced?Characteristics of Medical Evacuation by Train in Ukraine, 2022 Bempedoic Acid for Primary Prevention of Cardiovascular Events in Statin-Intolerant Patients Bempedoic Acid for High-Risk Primary Prevention of Cardiovascular Disease: Not a Statin Substitute but a Good Plan B Paolo Macchiarini: Disgraced surgeon is sentenced to 30 months in prison The deadly legacy of a stem cell charlatanRetract or be damned: a dangerous moment for science and the public Puberty blockers for young people will only be available as part of clinical research, says NHS Most advanced synthetic human embryos yet spark controversySixty seconds on . . . synthetic embryosHave a high-pitched voice? It might be in your genes Sequence variants affecting voice pitch in humans

LINKS BELOW |  OUR EPISODE THIS WEEK INCLUDES:Symptoms of Poor Gut HealthBenefits Seen in Professional and Corporate AthletesDefinition of a Leaky GutSupplementation Oxidative Stress + PeptidesAND MUCH MORETime Stamps

Drs Tucker and Nho discuss Preoperative Predictors of Achieving Clinically Significant Athletic Functional Status After Hip Arthroscopy for Femoroacetabular Impingement at Minimum 2-Year Follow-Up

Drs Tucker and Nho discuss Preoperative Predictors of Achieving Clinically Significant Athletic Functional Status After Hip Arthroscopy for Femoroacetabular Impingement at Minimum 2-Year Follow-Up

Interview with Dae Hyun Kim, author of Evaluation of Changes in Functional Status in the Year After Aortic Valve Replacement, and Emily Finlayson, MD, MS, author of Invasive Procedures to Improve Function in Frail Older Adults: Do Outcomes Justify the Intervention?

Interview with Dae Hyun Kim, author of Evaluation of Changes in Functional Status in the Year After Aortic Valve Replacement, and Emily Finlayson, MD, MS, author of Invasive Procedures to Improve Function in Frail Older Adults: Do Outcomes Justify the Intervention?

Interview with Mikel Izquierdo, Ph.D, and Nicolás Martínez-Velilla, PhD, authors of Effect of Exercise Intervention on Functional Decline in Very Elderly Patients During Acute Hospitalization: A Randomized Clinical Trial, and William J. Hall, MD, author of A Novel Exercise Intervention and Functional Status in Very Elderly Patients During Acute Hospitalization

Interview with Mikel Izquierdo, Ph.D, and Nicolás Martínez-Velilla, PhD, authors of Effect of Exercise Intervention on Functional Decline in Very Elderly Patients During Acute Hospitalization: A Randomized Clinical Trial, and William J. Hall, MD, author of A Novel Exercise Intervention and Functional Status in Very Elderly Patients During Acute Hospitalization

Episode nr. 2 is about how to detect changes in your chronic low back pain, including setting a personalized base line and learning how to work towards achievable goals using validated tools to capture your progress. Download Material Episode 2: find all the resources at: http://mybackrecovery.com/resources.page Activity-Progress Diary Body Chart & Numeric Pain Rating Scale Patient-Specific Functional Scale (PSFS) Roland Morris Disability Questionnaire Oswestry Disability Index check out this link that even scores for you PHQ-9 link for scoring instructions     Literature:  Calmels P, Bethoux F, Condemine A, Fayolle-Minon I. [Low back pain disability assessment tools]. AnnReadaptMed Phys. 2005;48(6):288-297. Ostelo RWJG, de Vet HCW. Clinically important outcomes in low back pain. Best Pract Res Clin Rheumatol. 2005;19(4):593-607. doi:10.1016/j.berh.2005.03.003. Roland M FJ. The Roland – Morris Disability Questionnaire and the Oswestry Disability Questionnaire. Spine (Phila Pa 1976). 2000;25(24):1994. doi:10.1097/00007632-200012150-00006. Guideline. Assessment and Management of Chronic Pain Health Care Guideline : Assessment and Management of Chronic Pain. Icsi. 2013;(November). Ostelo RWJG, Deyo RA, Stratford P, et al. Interpreting Change Scores for Pain and Functional Status in Low Back Pain. Spine (Phila Pa 1976). 2008;33(1):90-94. doi:10.1097/BRS.0b013e31815e3a10.   More infos at http://mybackrecovery.com/

Listen NowThe most expensive Medicare beneficiaries are not those with multiple chronic conditions.  They are those with chronic conditions AND functional impairment (i.e., those needing help with routine life activities).  For example, the 15% of Medicare enrollees with both chronic conditions and functional limitations disproportinally account for one-third of Medicare spending.  Alternatively, Medicare enrollees with three or more chronic conditions but no functional impairment (48%) account for roughly the same percent of spending (51%).  The challenge therefore both in improving quality care for the chronically ill and reducing costs (via, for example, reduced hospitalizations) is in improving long term care supports and services (LTSS). During this 26-minute podcast Dr. Alkema defines "functional limitation" and "care coordination", explains the current lack of care coordination for Medicare patients with chronic conditions and functional limitations, describes three exemplary models of care coordination and what Medicare can or should do to improve care for these patients.Dr. Gretchen Alkema currently serves as Vice President of Policy and Communications for The SCAN Foundation.  Prior to joining SCAN Dr. Alkema was the 2008-09 John Heinz Health and Aging Policy Fellow serving in the office of Sen. Blanche Lincoln.  Dr. Alkema earned her PhD at the University of Southern California's Davis School of Gerontology and and completed her post-doctoral training at the VA Greater Los Angeles Health Services Research and Development Center of Excellence.  Her academic research focused on evaluating innovative models of chronic care management and translating effective models into practice.  She is a Licensed Clinical Social Worker and has practiced in government and non-profit settings including community mental health, care management, adult day health care, residential care and post-acute rehabilitation.For background information concerning this topic see this paper by Georgetown's Harriet Komisar and Judy Feder: http://www.cahpf.org/docuserfiles/georgetown_trnsfrming_care.pdf  See also too SCAN's "10 Conversations to Plan for Aging with Dignity and Independence" at: http://www.thescanfoundation.org/10-conversations-plan-aging-dignity-and-independence. This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit www.thehealthcarepolicypodcast.com

Sat, 1 Jan 1994 12:00:00 +0100 https://epub.ub.uni-muenchen.de/10312/1/10312.pdf Katz, Jeffrey N.; Fossel, Anne H.; Lipson, Stephen J.; Liang, Matthew H.; Stucki, Gerold