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Still struggling with IBS symptoms, even after trying everything? It might not be “just IBS.” In the first episode of The Gut Show, Season 8, Dr. Mark Pimentel breaks down the connection between SIBO, IMO, ISO, and IBS, and what patients need to know about testing, treatment, and what's actually causing your symptoms. We talked about breath tests, stool tests, probiotics, antibiotics (like Rifaximin + Neomycin), the meds that cause SIBO, and more. Covered in this episode: Introducing Dr. Pimentel, MD [2:18] What is SIBO, ISO and IMO? [3:18] Should everyone with IBS do breath testing? [7:14] New guidelines that have come out [9:50] How should a patient navigate testing? [11:11] What about stool testing? [13:16] Negative test + symptoms or positive test without symptoms [16:50] What does normal mean? [18:44] Who does all 3 [20:39] Glucose vs Lactulose for the test [21:05] What causes these overgrowths? [21:52] The medication that WILL make you have SIBO [23:53] MAST cells, IBD, endometriosis [24:34] Treatment [32:07] Rifaximin [34:19] Any Statin or seaweed based treatment updates? [37:51] Neomycin [39:25] Elemental diet [41:23] What Dr. Pimentel wants for his patients [45:17] Probiotics [46:40] The role of metabolic disorders [48:22] Rapid fire questions [50:59] Mentioned in this episode: MASTER Method Membership Take the quiz: What's your poop personality? Sponsors of The Gut Show: FODZYME is the world's first enzyme supplement specialized to target FODMAPs. When sprinkled on or mixed with high-FODMAP meals, FODZYME's novel patent-pending enzyme blend breaks down fructan, GOS and lactose before they can trigger bloating, gas and other digestive issues. With FODZYME, enjoy garlic, onion, wheat, Brussels sprouts, beans, dairy and more — worry free! Discover the power of FODZYME's digestive enzyme blend and eat the foods you love and miss. Visit fodzyme.com and save 20% off your first order with code THEGUTSHOW. One use per customer. Gemelli Biotech offers trusted, science-backed at-home tests for conditions like SIBO, IMO, ISO, and post-infectious IBS. Their Trio-Smart breath test measures all three key gases: hydrogen, methane, and hydrogen sulfide to detect different forms of microbial overgrowth. And for those with IBS symptoms, IBS-Smart is a simple blood test that can confirm post-infectious IBS with clinical accuracy. You simply order the test, complete it at home, send it back, and get clinically backed results in about a week that you can take to your provider! Find out which tests are right for you at getgutanswers.com and use code ERINJUDGE25 to save $25 on your order! About our speaker: Mark Pimentel, MD, FRCP(C), is a Professor of Medicine at Cedars-Sinai and Professor of Medicine and of Gastroenterology through Geffen School of Medicine. Dr. Pimentel is also the Executive Director of the Medically Associated Science and Technology (MAST) program at Cedars-Sinai, an enterprise of physicians and researchers dedicated to the study of the gut microbiome in order to develop effective diagnostic tools and therapies to improve patient care. As a physician and researcher, Dr. Pimentel has served as a principal investigator or co-investigator for numerous basic science, translational and clinical investigations of irritable bowel syndrome (IBS) and the relationship between gut flora composition and human disease. This research led to the first ever blood tests for IBS, ibs-smart™, the only licensed and patented serologic diagnostic for irritable bowel syndrome. The test measures the levels of two validated IBS biomarkers, anti-CdtB and anti-vinculin. A pioneering expert in IBS, Dr. Pimentel's work has been published in the New England Journal of Medicine, Annals of Internal Medicine, American Journal of Physiology, American Journal of Medicine, American Journal of Gastroenterology and Digestive Diseases and Sciences, among others. Dr. Pimentel has presented at national and international medical conferences and advisory boards. He is a diplomate of the American Board of Internal Medicine (Gastroenterology,) a fellow of the Royal College of Physicians and Surgeons of Canada and a member of the American Gastroenterological Association, the American College of Gastroenterology, and the American Neurogastroenterology and Motility Society. Dr. Pimentel completed 3 years of an undergraduate degree in honors microbiology and biochemistry at the University of Manitoba, Canada. This was followed by his medical degree, and his BSc (Med) from the University of Manitoba Health Sciences Center in Winnipeg, Manitoba, Canada, where he also completed a residency in internal medicine. His medical training includes a fellowship in gastroenterology at the UCLA Affiliated Training Program. Connect with Erin Judge, RD: IG: https://www.instagram.com/erinjudge.rd TikTok: https://www.tiktok.com/@erinjudge.rd Work with Gutivate: https://gutivate.com/services
Are you enjoying this? Are you not? Tell us what to do more of, and what you'd like to hear less of. The Reykjavík Grapevine's Iceland Roundup brings you the top news with a healthy dash of local views. In this episode, Grapevine publisher Jón Trausti Sigurðarson is joined by Heimildin journalist Aðalsteinn Kjartansson, and Grapevine friend and contributor Sindri Eldon to roundup the stories making headlines in recent weeks. On the docket this week are: ✨ Two French tourists were found dead at a hotel in Reykjavík last Saturday. A third person, a woman, has been detained. Police suspect a double homicide. The woman detained, along with the two victims are reported to have had stab wounds. Investigation is ongoin.✨Icelandic low fair airline Play Air, may soon move its operations abroad following a takeover bid by some of the current management of the company.✨A man who had been missing on Esja on last Monday and Tuesday was found dead on the slopes of Kistufell, a part of Mt. Esja. He was discovered around 16:00 on Tuesday.✨The orca that stranded earlier this week in Grafarvogur, Reykjavík, was euthanised. After swimming back out to sea on Wednesday, it stranded again on Friday at Kjalarnes. According to MAST's Chief Veterinary Officer, the decision was made with animal welfare as the guiding principle.✨An old Douglas Dakota aircraft, purchased this March by the landowners of Sólheimasandur from the Icelandic DC-3 Friends Association, has been transported from Keflavík Airport to rural South Iceland. The plan is to place the fuselage near the famous US Navy plane wreck, which has become one of the South Coast's most visited tourist attractions.✨ A potential disaster was narrowly avoided when a training aircraft lost its nose wheel over Austurvöllur while approaching Reykjavík Airport. The wheel landed in front of the Alþingi building. No one was injured, and the plane touched down safely at Reykjavík Airport.------------------------------------------------------------------------------------------SHOW SUPPORTSupport the Grapevine's reporting by becoming a member of our High Five Club: https://steadyhq.com/en/rvkgrapevine/You can also support the Grapevine by shopping in our online store: https://shop.grapevine.is------------------------------------------------------------------------------------------ This is a Reykjavík Grapevine podcast.The Reykjavík Grapevine is a free alternative magazine in English published 18 times per year, biweekly during the spring and summer, and monthly during the autumn and winter. The magazine covers everything Iceland-related, with a special focus culture, music, food and travel. The Reykjavík Grapevine's goal is to serve as a trustworthy and reliable source of information for those living in Iceland, visiting Iceland or interested in Iceland. Thanks to our dedicated readership and excellent distribution network, the Reykjavík Grapevine is Iceland's most read English-language publication. You may not agree with what we write or publish, but at least it's not sponsored content.www.grapevine.is
Pentecost Sunday | 06.08.2025 | Fr. CJ Mast by Lourdes Denver
In this episode of The Sunday Roast, the team discuss signs of market recovery, with standout moves from Celadon, Mila, BMV, and Mast Energy. They also cover major geopolitical headlines, including Trump and Putin's high-stakes call on Ukraine, and Labour's transport pledges and winter fuel U-turn. Special guest Leon Coetzer, CEO of Jubilee Metals, joins to discuss the company's strategic $90m divestment of its chrome and PGM assets to double down on Zambian copper. Plus: a look at Mirriad's JV deal, GreenRoc's EU boost, and a farewell (for now?) to Mobland. 00:00 - 00:14:40 Weekly News Roundup 00:14:40 #JLP Interview 00:43:06 #HUI 00:44:02 #CEL 00:44:09 #BMV 00:44:24 #MILA 00:45:40 #MAST 00:47:04 #GROC 00:56:25 #TUN 00:57:15 #GMET 00:59:23 Hamilton Project 01:02:11 #HEX 01:03:52 #PR1 01:06:26 #ARS 01:06:53 #UFO 01:07:22 #MIRI 01:08:45 #EST 01:09:32 TV Recommendation Disclaimer & Declaration of Interest This podcast may contain paid promotions, including but not limited to sponsorships, endorsements, or affiliate partnerships. The information, investment views, and recommendations provided are for general informational purposes only and should not be construed as a solicitation to buy or sell any financial products related to the companies discussed. Any opinions or comments are made to the best of the knowledge and belief of the commentators; however, no responsibility is accepted for actions based on such opinions or comments. The commentators may or may not hold investments in the companies under discussion. Listeners are encouraged to perform their own research and consult with a licensed professional before making any financial decisions based on the content of this podcast.
Welcome to a transformative episode of our podcast, where we delve into the world of breast implant illness (BII) with leading experts and personal stories that will captivate your attention! Join us as Dr. Robert Whitfield, a renowned board-certified plastic surgeon, unravels the complexities of BII alongside wellness expert Andi Lew and functional medicine specialist Dr. Tania Ash. Today, Dr. Whitfield underscores the critical importance of understanding BII and advocates for comprehensive, patient-centered care. Andi Lew shares her personal journey with BII, highlighting the challenges she faced in finding knowledgeable providers and the emotional toll it took on her. Meanwhile, Dr. Tania Ash delves into diagnostic approaches and emphasizes the role of detoxification in the recovery process. If you're trying to understand the intricacies of BII, holistic treatment, and supportive care for women affected by this condition, tune in to this engaging conversation that promises to inform, inspire, and empower. Bio: Dr. Tania Ash Dr. Tania has over three decades of medical expertise, including the past 21 years in functional medicine, with a specialization in CFS/MCAS. She is a graduate of Melbourne University Medical School and holds two postgraduate fellowships, both as a GP (RACGP) and in functional medicine with A5M. Creating awareness, diagnosing, and healing from BII/MCAS is her life mission and commitment. Her focus is to thread together systemic symptoms, drill down to the root causes, and optimise the body terrain to heal. [ https://mergehealth.com/au/team/dr-tania-ash (https://andilew.com/)] Bio: Andi Lew Andi Lew is a TV host, leading Wellness Expert & certified Wellness and Explant coach. Author of 10 books, including Treasured Chest, Exposing Explants and Empowering You. [ https://andilew.com (https://andilew.com)] Show Highlights: Connection Between MCAS and BII (00:09:54) How MCAS relates to BII, highlighting the immune response to foreign bodies The Role of Mast Cells (00:11:07) Mast cells function in the body, and their connection to inflammatory responses in BII Body's Healing Mechanisms (00:12:07) The body's natural healing processes and how they relate to the challenges posed by breast implants Understanding Inflammatory Responses (00:13:24) Recognizing implants as potential inflammatory drivers in the body Genetic Predispositions (00:15:19) Role of genetics in BII and the need for better preoperative counseling regarding risks Autoimmunity Risks (00:17:16) Discussing studies showing an increased risk of autoimmunity associated with breast implants Navigating Patient Decisions (00:18:08) Challenges of helping patients make informed decisions about surgery and the implications of implants Daily Parasympathetic Practices (00:39:22) Daily practices like yoga and meditation for nervous system health Toxic Load and Parasites (00:40:30) The need to detoxify and address hidden parasites in the body Links and Resources Let's Connect Podcast: https://podcasts.apple.com/gb/podcast/breast-implant-illness/id1678143554 Spotify: https://open.spotify.com/show/1SPDripbluZKYsC0rwrBdb?si=23ea2cd9f6734667 TikTok: https://www.tiktok.com/@drrobertwhitfield?t=8oQyjO25X5i&r=1 IG: https://www.instagram.com/breastimplantillnessexpert/ FB: https://www.facebook.com/DrRobertWhitfield Linkedin: https://www.linkedin.com/in/dr-robert-whitfield-md-50775b10/ X: https://x.com/rob_whitfieldmd Read this article - https://www.breastcancer.org/treatment/surgery/breast-reconstruction/types/implant-reconstruction/illness/breast-implant-illness Shop: https://drrobssolutions.com SHARP: https://www.harp.health NVISN Labs - https://nvisnlabs.com/ Get access to Dr. Rob's Favorite Products below: Danger Coffee - Use our link for mold free coffee - https://dangercoffee.com/pages/mold-free-coffee?ref=ztvhyjg JASPR Air Purifier - Use code DRROB for the Jaspr Air Purifier - https://jaspr.co/ Echo Water - Get high quality water with our code DRROB10 - https://echowater.com/ BallancerPro - Use code DRROBVIP for the world's leader in lymphatic drainage technology - https://ballancerpro.com Ultrahuman - Use code WHITFIELD10 for the most accurate wearable - https://www.ultrahuman.com/ring/buy/us/?affiliateCode=drwhitfield
Kje vse lahko v kuhinji uporabljamo svinjsko mast, je zanimalo našega poslušalca. Sestra Nikolina pravi, da jo lahko uporabimo vsepovsod: na svinjski masi lahki cvremo, pražimo, opečemo meso … Jedi bodo imele drugačen, za mnoge boljši okus. Mast odmerjamo po žlicah, ne v velikih količinah. Svinjsko salo pa uporabljamo tudi za piškote, tudi za valjane kekse, mašinske - strojne piškote. Salo je odlično tudi za mazanje modelov ...
AI is moving fast – and if you're a real estate investor or business owner, you need to keep up. In this episode of Eat Sleep Invest, Bryan Driscoll chats with Jonathan Mast of Whitebeard Strategies to cut through the noise and share practical, no-fluff ways to use AI in your business. From ChatGPT and Claude to Google Gemini and Perplexity, we break down what these tools actually do, how to get started without getting overwhelmed, and how to make AI work for you – not replace you. You'll learn: The best AI tools and what they're good at How to use custom GPTs trained on your voice and data The power of prompts (and how to write them) Using AI to save time, boost content, and simplify decision-making Why AI should amplify human connection – not eliminate it Real examples of using AI for sales, marketing, P&L, family stories, and more Timestamps: 00:00 – Intro 01:00 – Jonathan's pivot into AI and coaching 02:30 – Where to start with AI tools as a business owner 04:00 – ChatGPT vs Gemini vs Claude vs Perplexity 08:30 – Deep research and how Google Gemini 2.5 is changing the game 11:00 – Using personality tests to train ChatGPT to match your voice 13:00 – Collaborating with AI instead of just asking for answers 16:00 – Voice-to-text workflows for better output 18:00 – What is a prompt and how to write better ones 21:00 – Using AI in your daily life (fitness, P&L, decision support) 24:00 – Turning transcripts into action 26:00 – AI-generated audio for voicemails and productivity 28:30 – Why personal brand matters more than ever 30:00 – Automating vs amplifying in your sales process 32:00 – Custom GPTs for scaling your content 34:00 – AI stories for kids + teaching your family 36:30 – Making complex topics (like the Bible) easier to understand 38:00 – Learning AI without overwhelm – the 30-min-a-day method 41:00 – Capturing voice ideas with AudioPen 43:00 – Google's VO3 and Flow – game-changing AI for video 44:30 – Where to find Jonathan and his courses Resources: Learn more from Jonathan: jonathanmast.com Join his free Facebook Group: AI Prompts for Entrepreneurs Looking for high-quality motivated seller leads? Visit motivatedleads.com
In this episode of The Sunday Roast, we're joined by Pieter Krügel, CEO of Mast Energy Developments (LSE: MAST), to discuss the company's recent £5 million funding initiative. This two-stage financing comprises a £350,000 interest-free convertible loan note from Big Sky Management Limited and a proposed £4.65 million equity fundraise through a warrant instrument, aimed at bolstering working capital and expanding their energy projects. We also welcome Daniel Gee, founder and CEO of Founder of Pri0r1ty AI (AIM: PR1), to delve into the company's recent expansion into cryptocurrency payments. Pri0r1ty has integrated Bitcoin and other cryptocurrencies into its online onboarding process through a partnership with Coinbase Commerce. This move not only caters to a growing demographic of tech-savvy business users but also aligns with their newly adopted Bitcoin Treasury Management Policy, reflecting a strategic shift towards embracing digital assets.    Additionally, we cover the week's major market stories, including potential tariff impacts from Trump, Elon Musk's latest moves with Dogecoin, and notable political developments. We wrap up with insights into the FTSE 100 and broader market trends. 00:00 - 00:11:50 Weekly News Roundup 00:11:50 #MAST Interview 00:21:40 #PR1 Interview 00:38:01 #ICON 00:38:09 #BLU 00:45:04 #CGNR 00:45:44 #CHLL 00:46:25 #CEL 00:46:48 #GMET 00:46:57 #TUN 00:47:45 #EPP 00:48:33 #GGP 00:50:10 #BMV 00:58:48 TV Recommendation Disclaimer & Declaration of Interest This podcast may contain paid promotions, including but not limited to sponsorships, endorsements, or affiliate partnerships. The information, investment views, and recommendations provided are for general informational purposes only and should not be construed as a solicitation to buy or sell any financial products related to the companies discussed. Any opinions or comments are made to the best of the knowledge and belief of the commentators; however, no responsibility is accepted for actions based on such opinions or comments. The commentators may or may not hold investments in the companies under discussion. Listeners are encouraged to perform their own research and consult with a licensed professional before making any financial decisions based on the content of this podcast.
Mast cell activation syndrome isn't widely recognized, but for many women, it may explain years of pain, fatigue, and hormone related chaos no one could solve.I see a lot of patients who are struggling with fatigue, pain, and hormone symptoms that don't seem to make sense on paper. And I've noticed a pattern but I wanted to talk to someone who lives in the complexity of it every day.Dr. Tania Dempsey, is one of the few physicians who's helped bring mast cell activation syndrome (MCAS) into the spotlight. Years ago, she was treating a patient who just wasn't getting better until she stumbled on a paper about mast cells that changed everything. That one article led to a phone call, a new way of thinking, and a career shifting collaboration with one of the leading voices in the field.In this conversation, we explore how MCAS shows up in gynecology especially in cases involving PCOS, perimenopause, and unexplained pelvic pain. We discuss why some patients are unusually sensitive to progesterone, how inflammation fuels insulin resistance, and what's actually going on when mast cells become overactive. We also get into the clinical triad so many of us see MCAS, hypermobility, and POTS and how they often appear together in patients who are struggling to get answers.Tania also talks about how she built her practice by spending more time listening to her patients and trusting that their symptoms meant something, even when the labs didn't show it. Highlights:What mast cells do and how they become overactive in MCAS.The overlooked link between PCOS, perimenopause, and mast cell dysfunction.Why some patients react badly to progesterone—and what to do about it.How GLP-1 drugs like Ozempic may help calm inflammation in MCAS.What to know before seeking a diagnosis or starting treatment.If this episode opened your eyes or gave you language for what you've been going through, please subscribe, leave a review, and drop a comment. I'd love to hear what resonated most with you.Dr. Dempsey's Bio:Dr. Tania Dempsey, MD, ABIHM is a world-renowned expert in complex, multisystem diseases. As founder of the AIM Center of Personalized Medicine, in Purchase, NY, Dr. Dempsey uses functional and integrative medicine to get to the patient's root cause(s) of illness and to help them find a path to optimum health. Her extensive knowledge and experience with Mast Cell Activation Syndrome, Mold, and Lyme and other Vector-Borne Diseases, has propelled her to the forefront of the medical community as a recognized and trusted speaker, researcher, advocate, and physician.Dr. Dempsey is Board-Certified in Internal Medicine and Integrative and Holistic Medicine. She received her MD degree from The Johns Hopkins University School of Medicine and her BS degree from Cornell University. She completed her Internal Medicine Residency at NYU Medical Center.She was recently elected to the Board of Directors of ILADS (International Lyme and Associated Diseases Society). She is also a member of the U.S. ME/CFS Clinician Coalition, the American Academy of Ozonotherapy, and ISSWSH (International Society for the Study of Women's Sexual Health).She is an accomplished international speaker, writer and thought leader and has 8 peer-reviewed articles in the medical literature. Her latest endeavor is cohosting the new podcast, Mast Cell Matters.Get in Touch with Dr. Dempsey:WebsiteFacebookInstagram
On this episode of 'My Friend Autism', Orion Kelly explores the topic of mast cells, brain inflammation and autism. Orion Kelly is an Autistic YouTuber, podcaster, author, actor and advocate. Find out more about his podcast and YouTube channel's at Orion's website: https://orionkelly.com.au All rights reserved.
Jacob Beautemps ist ein deutscher Science-Tuber und Wissenschaftsjournalist. Seit 2018 moderiert er den YouTube-Kanal „Breaking Lab“ mit fast 700.000 Abonnenten. Er will Lust auf Innovationen in Deutschland machen. Wie diese aussehen könnten und was aktuell entwickelt wird, beschreibt er in seinem Buch „Unsere Zukunft neu denken – Innovationen, die unser Leben besser machen.“ Er reist gerne um die Welt und trifft für seine Videos Expertinnen und Experten, die an der Zukunft arbeiten. Was ihn an Bill Gates inspiriert – den er bereits mehrfach getroffen hat und wie es ist, einen 50 Meter hohen Mast hinaufzuklettern, erzählt er in dieser Folge. Denn schließlich entsteht in Deutschland das größte Windrad der Welt. Podcasttipp Wild Wild Web - Geschichten aus dem Internet https://www.ardaudiothek.de/sendung/wild-wild-web/94702896/
6th Sunday of Easter | 05.25.2025 | Fr. CJ Mast by Lourdes Denver
Now that Primo is no longer available, will Equipoise be the next go-to steroid to control estrogen? Plus Steroid QA Drugs N Stuff Podcast - Dave Crosland & Scott McNally 0:00 Tren soldiers 0:40 Intro 3:00 Equipoise to control estrogen? 7:00 test conversion vs equipoise conversion 8:15 Test to EQ ratios 9:50 Estrogen and hematocrit 12:30 figuring out how well EQ controls estrogen for YOU 16:10 Prostate Cancer Awareness Event 18:30 Dbol making you feel sick? 21:00 What can you run for joint issues? 24:00 Test & Mast vs Test at same total Mg? 30:45 Removing test and using Dbol for estrogen 33:30 Statin to Control Cholesterol? 37:30 Cycle for Older guy with THREE orals? 39:50 Getting Bloods done at FitExpo 42:45 How important is ester weight 47:25 Minimal amount to cycle? 52:20 Steroid Use and Donating Blood 55:30 Dave's Car Talk 1:03:30 Operator Syndrome and gear in the military
1 - Mylo Vs Miami Sound Machine - Drop The Pressure Vs Doctor B 2 - Michael Grey - The Weekend 3 - Flo Rida - I Cry 4 - The Drill - The Drill 5 - David Guetta ft Taio Cruz & Ludacris - Little Bad Girl 6 - Remady - No superstar (Willy William Remix) 7 - Martin Solveig - Everybody 8 - David Guetta & Rihanna - Who's That Chick 9 - Swedish House Mafia & John Martin - Don't You Worry Child 10 - Phoenix - If I Ever Feel Better 11 - Fatal bazooka - Trankillement 12 - Mika - Relax (DJ Mast Rework) 13 - Mr Vegas - Pull Up 14 - Rihanna - Please Don't Stop The Music 15 - Stromae - Alors On Danse 16 - Lady Gaga - Just Dance 17 - Sophie Ellis Bextor VS Ricchi & Poveri - Murder on the Dancefloor (DJ Mast Mash'up) 18 - Taio Cruz - Dynamite 19 - Selena Gomez & The Scene - Love You Like A Love Song 20 - King Of House - Can You Feel It 21 - Keyshia Cole - Last Night 22 - K-Maro - Femme like u 23 - Lady Gaga - Poker Face 24 - Timbaland feat Keri Hilson - The Way i Are 25 - Christophe Willem - Double jeu 26 - Jamiroquai - Little L 27 - Pussycat Dolls feat Busta Rhymes - Don't Cha 28 - Gwen Stefani feat Akon - Sweet Escape 29 - Anastacia - I'm Outta Love 30 - Stromae - Papaoutai
Welcome back to The Sunday Roast! After a much-needed break in the Welsh mountains, the lads return with your weekly dose of market insight, political drama, and a few laughs along the way. This week, we look at the UK's latest deal with the EU—designed to ease post-Brexit tensions by improving trade terms and defence ties—but is it a win, or has the UK given away more than it's gained? We're joined by Luke Sartain, CEO of Narwhal Media Group, who talks through the rise of AI-driven lead generation, the vision behind SpotDiff, and how agentic AI is reshaping digital marketing. Luke also shares the latest on their new funding and what's next for the business. In the Movers & Shakers: Defence Holdings (ALRT) soared 300% after major board appointments, Mila Resources (MILA) surged 80% following high-grade gold assay results, and MAST climbed 58%. On the downside, Totally plc dropped 77% amid restructuring concerns, while Pantheon Resources slid 40% after a disappointing update at Megrez-1. RNS headlines include Panthera Resources launching a $1.58bn arbitration claim against India over its Bhukia gold project and GEO Exploration announcing a 23% upgrade in prospective resources to 4.31 billion barrels offshore Namibia. Tune in for the latest from the markets, a cracking guest, and the usual Sunday Roast banter. 00:00 - 00:16:27 Weekly News Roundup 00:16:27 #NMG Interview 01:02:13 #ALRT 01:02:47 #MILA 01:04:42 #MAST 01:05:57 #TLY 01:06:35 #PANR 01:06:56 #GEO 01:08:18 #GGP 01:09:26 #CHLL 01:10:16 #GMET 01:15:28 TV Recommendation Disclaimer & Declaration of Interest This podcast may contain paid promotions, including but not limited to sponsorships, endorsements, or affiliate partnerships. The information, investment views, and recommendations provided are for general informational purposes only and should not be construed as a solicitation to buy or sell any financial products related to the companies discussed. Any opinions or comments are made to the best of the knowledge and belief of the commentators; however, no responsibility is accepted for actions based on such opinions or comments. The commentators may or may not hold investments in the companies under discussion. Listeners are encouraged to perform their own research and consult with a licensed professional before making any financial decisions based on the content of this podcast.
In this encore episode, we detail the intestinal mycobiome and the mechanisms by which beneficial microbes aid in regulating opportunistic fungal species: Candida albicans. We discuss Candida overgrowth virulence and how disruptions in microbial balance, immune function, and epithelial integrity impact Candida's pathogenicity. Additionally, we discuss the role of mast cells in the lamina propria, their involvement in mucosal immunity, and how Mast Cell Activation Syndrome (MCAS) can be exacerbated by fungal dysbiosis / microbial imbalances.Topics: 1. Introduction - The intestinal mycobiome and its role in intestinal health. - Regulating populations of opportunistic fungal species like Candida albicans.- Mast cell activation syndrome (MCAS) intro. 2. Structure of the Intestinal Barrier- The microbiome and mucus layer: microbes, mucins, antimicrobial peptides, sIgA.- The epithelial monolayer: enterocytes, goblet cells, Paneth cells, enteroendocrine cells…- Tight junction proteins and paracellular transport.- The lamina propria beneath the epithelium: immune cells and more. 3. Candida's Pathogenicity and Barrier Disruption- Exists primarily in its yeast form, regulated by microbial competition, host immune defenses, antifungal peptides. - Secretory IgA (sIgA) and immune surveillance mechanisms help regulate fungal populations. - Chronic stress, immune suppression, and dysbiosis can deplete sIgA, increasing susceptibility to Candida proliferation. - Environmental triggers such as immune suppression, microbial depletion, inflammatory cytokines.- Yeast-to-hyphal transition, deeper tissue invasion. - Secreted aspartyl proteinases (SAPs), phospholipases, candidalysin: epithelial damage.- Pattern recognition receptors (PRRs) and overgrowth detection. 4. Impact of Beneficial Bacteria on Candida Overgrowth - Beneficial bacteria compete with Candida for nutrients and epithelial adhesion sites. - Short-chain fatty acids (SCFAs) produced by beneficial bacteria.- Depletion of beneficial bacteria removes ecological resistance, allowing Candida to proliferate unchecked. 5. Mast Cells in the Lamina Propria and Their Role in Intestinal Immunity- Mast cell location - Upon activation, mast cells release histamine, cytokines, proteases, and more that regulate gut immune responses. - Histamine can increase gut permeability and modulate local immune activation. - Tryptase and chymase. - Pro-inflammatory cytokines. 6. Mast Cell Activation Syndrome (MCAS) - Mast cell hyperactivation.- Environmental triggers, toxins, chronic infections, and stress. - Candida overgrowth and mast cell activation.- Addressing microbial imbalances and reducing the body's total microbial, chemical, and toxin burden.- A diverse microbiome. 7. Conclusion- Candida overgrowth and regulation via immune defenses and beneficial bacterial competition.- MCAS, root cause approach.Get Chloe's Book Today! "75 Gut-Healing Strategies & Biohacks" Follow Chloe on Instagram @synthesisofwellnessVisit synthesisofwellness.com
Jonathan Mast, the founder of White Beard Strategies, discusses the transformative impact of AI and large language models on professional services, particularly within the legal industry. Jonathan shares insights on the efficiency benefits of generative AI, such as handling mundane tasks and drafting documents, emphasizing how lawyers can leverage AI to save substantial time and align better with client expectations. He shares details about his consulting approach, which involves coaching teams to integrate AI into their workflows, thereby enhancing productivity without significantly increasing costs. Jonathan also explores the evolution of AI, comparing the shift from typewriters to word processors to the current transition to AI tools. He advises that, unlike outdated methods, AI can offer significant advantages if properly implemented and utilized, either personally or by empowering administrative staff. Jonathan touches on the importance of specialized AI tools tailored to specific legal fields, the significance of contextual language understanding, and the need for lawyers to embrace these advanced technologies to stay competitive. He advocates for a subscription model in AI consultancy, similar to the modern legal practice models, providing continuous support and adaptation in this rapidly evolving field.__________________________Check out Jonathan Mast's website and YouTube Channel.Sign up for Paxton, my all-in-one AI legal assistant, helping me with legal research, analysis, drafting, and enhancing existing legal work product.Get Connected with SixFifty, a business and employment legal document automation tool.Sign up for Gavel, an automation platform for law firms.Check out my other show, the Law for Kids Podcast.Visit Law Subscribed to subscribe to the weekly newsletter to listen from your web browser.Prefer monthly updates? Sign up for the Law Subscribed Monthly Digest on LinkedIn.Want to use the subscription model for your law firm? Sign up for the Subscription Seminar waitlist at subscriptionseminar.com.Check out Mathew Kerbis' law firm Subscription Attorney LLC. Get full access to Law Subscribed at www.lawsubscribed.com/subscribe
Lionel wraps up the show talking about the Mexican naval vessel colliding with the Brooklyn Bridge and assassination conspiracies. Learn more about your ad choices. Visit megaphone.fm/adchoices
What if the diagnosis was just the beginning—and the root cause was hiding in plain sight? In this riveting episode, Dr. Linda Bluestein welcomes pediatrician and integrative medicine expert Dr. Pejman Katiraei, whose work with children struggling with autism, mold exposure, and mast cell activation reveals a shocking truth: many kids aren't just neurodivergent—they have neuroinflammation. Together, they peel back the layers on what's really driving autistic behaviors, why some children can't tolerate food, noise, or even hugs—and how mast cells and histamine might be behind it all. Dr. Katiraei shares remarkable stories of transformation, explains why traditional testing often fails, and reveals a controversial treatment that's changing lives. If your child is sensitive, reactive, or struggling to connect—and you've been told it's just "behavioral"—this conversation might rewrite what you thought was possible. Takeaways: One child's refusal to eat broccoli held more answers than anyone expected. Could colic be the first warning sign of central inflammation? He couldn't feel love—until one unlikely medication changed everything. A house tested clean… but the child kept getting worse. Why? Some diagnoses miss what's burning beneath the surface. Find the episode transcript here. Reference Links: https://pubmed.ncbi.nlm.nih.gov/18626069/ https://www.sciencedirect.com/science/article/abs/pii/S0941950014001936The Dust Testhttps://www.thedusttest.com/https://www.mayoclinic.org/drugs-supplements/itraconazole-oral-route/description/drg-20071421 https://www.sciencedirect.com/science/article/abs/pii/S0149291813001823 https://pmc.ncbi.nlm.nih.gov/articles/PMC10932299/ Watch Ep 32 with Dr. Jessica Eccles: https://youtu.be/BmIFATctyzk Watch Ep 47 with Dr. Jessica Eccles: https://youtu.be/nhsLDzLpUWE Watch Ep 139 with Dr. Theoharides: https://youtu.be/u1pxvAzXh7M Connect with YOUR Hypermobility Specialist, Dr. Linda Bluestein, MD at https://www.hypermobilitymd.com/. Thank YOU so much for tuning in. We hope you found this episode informative, inspiring, useful, validating, and enjoyable. Join us on the next episode for YOUR time to level up your knowledge about hypermobility disorders and the people who have them. Join YOUR Bendy Bodies community at https://www.bendybodiespodcast.com/. YOUR bendy body is our highest priority! https://wholistickids.com/ https://www.wholisticminds.com/ https://pkatiraei.substack.com https://www.youtube.com/@pkatiraei https://www.instagram.com/wholistickids?igsh=MXNyd3I3NTc0aGIydw== Use this affiliate link for Algonot to get an extra 5% off your entire order: https://algonot.com/coupon/bendbod/ FTC: This video is not sponsored. Links are commissionable, meaning I may earn commission from purchases made through links. Connect with the HypermobilityMD: YouTube: youtube.com/@bendybodiespodcast Instagram: https://www.instagram.com/hypermobilitymd/ Facebook: https://www.facebook.com/BendyBodiesPodcast Facebook: X: https://twitter.com/BluesteinLinda LinkedIn: https://www.linkedin.com/in/hypermobilitymd/ Newsletter: https://hypermobilitymd.substack.com/ Shop my Amazon store https://www.amazon.com/shop/hypermobilitymd Learn more about Human Content at http://www.human-content.com Podcast Advertising/Business Inquiries: sales@human-content.com Part of the Human Content Podcast Network
What if the diagnosis was just the beginning—and the root cause was hiding in plain sight? In this riveting episode, Dr. Linda Bluestein welcomes pediatrician and integrative medicine expert Dr. Pejman Katiraei, whose work with children struggling with autism, mold exposure, and mast cell activation reveals a shocking truth: many kids aren't just neurodivergent—they have neuroinflammation. Together, they peel back the layers on what's really driving autistic behaviors, why some children can't tolerate food, noise, or even hugs—and how mast cells and histamine might be behind it all. Dr. Katiraei shares remarkable stories of transformation, explains why traditional testing often fails, and reveals a controversial treatment that's changing lives. If your child is sensitive, reactive, or struggling to connect—and you've been told it's just "behavioral"—this conversation might rewrite what you thought was possible. Takeaways: One child's refusal to eat broccoli held more answers than anyone expected. Could colic be the first warning sign of central inflammation? He couldn't feel love—until one unlikely medication changed everything. A house tested clean… but the child kept getting worse. Why? Some diagnoses miss what's burning beneath the surface. Find the episode transcript here. Reference Links: https://pubmed.ncbi.nlm.nih.gov/18626069/ https://www.sciencedirect.com/science/article/abs/pii/S0941950014001936The Dust Testhttps://www.thedusttest.com/https://www.mayoclinic.org/drugs-supplements/itraconazole-oral-route/description/drg-20071421 https://www.sciencedirect.com/science/article/abs/pii/S0149291813001823 https://pmc.ncbi.nlm.nih.gov/articles/PMC10932299/ Watch Ep 32 with Dr. Jessica Eccles: https://youtu.be/BmIFATctyzk Watch Ep 47 with Dr. Jessica Eccles: https://youtu.be/nhsLDzLpUWE Watch Ep 139 with Dr. Theoharides: https://youtu.be/u1pxvAzXh7M Connect with YOUR Hypermobility Specialist, Dr. Linda Bluestein, MD at https://www.hypermobilitymd.com/. Thank YOU so much for tuning in. We hope you found this episode informative, inspiring, useful, validating, and enjoyable. Join us on the next episode for YOUR time to level up your knowledge about hypermobility disorders and the people who have them. Join YOUR Bendy Bodies community at https://www.bendybodiespodcast.com/. YOUR bendy body is our highest priority! https://wholistickids.com/ https://www.wholisticminds.com/ https://pkatiraei.substack.com https://www.youtube.com/@pkatiraei https://www.instagram.com/wholistickids?igsh=MXNyd3I3NTc0aGIydw== Use this affiliate link for Algonot to get an extra 5% off your entire order: https://algonot.com/coupon/bendbod/ FTC: This video is not sponsored. Links are commissionable, meaning I may earn commission from purchases made through links. Connect with the HypermobilityMD: YouTube: youtube.com/@bendybodiespodcast Instagram: https://www.instagram.com/hypermobilitymd/ Facebook: https://www.facebook.com/BendyBodiesPodcast Facebook: X: https://twitter.com/BluesteinLinda LinkedIn: https://www.linkedin.com/in/hypermobilitymd/ Newsletter: https://hypermobilitymd.substack.com/ Shop my Amazon store https://www.amazon.com/shop/hypermobilitymd Learn more about Human Content at http://www.human-content.com Podcast Advertising/Business Inquiries: sales@human-content.com Part of the Human Content Podcast Network Learn more about your ad choices. Visit megaphone.fm/adchoices
Listen to SJ react to the Maverick getting the #1 pick in the NBA draft and the semi-finals of the playoffs.
The first Temu chat.The Bodybuilding-friendly HRT Clinic - Get professional medical guidance on peptides AND optimizing your health as a man or bodybuilder:[ Pharma Test, IGF1, Tesamorelin, Glutathione, BPC, Semaglutide, Var troche, etc]https://transcendcompany.com/patient-intake-form/?ls=Nyle+NaygaWatch it: https://www.youtube.com/watch?v=6Ihq4tIzyS8&t=5618sRP Hypertrophy Training App: rpstrength.com/nylePlease share this episode if you liked it. To support the podcast, the best cost-free way is to subscribe and please rate the podcast 5* wherever you find your podcasts. Thanks for watching.To be part of any Q&A, follow trensparentpodcast or nylenayga on instagram and watch for Q&A prompts on the story https://www.instagram.com/trensparentpodcast/Huge Supplements (Protein, Pre, Defend Cycle Support, Utilize GDA, Vital, Astragalus, Citrus Bergamot): https://www.hugesupplements.com/discount/NYLESupport code 'NYLE' 10% off - proceeds go towards upgrading content productionYoungLA Clothes: https://www.youngla.com/discount/nyleCode ‘NYLE' to support the podcastLet's chat about the Podcast:Instagram: https://www.instagram.com/trensparentpodcast/TikTok: https://www.tiktok.com/@transparentpodcastPersonalized Bodybuilding Program: https://www.nylenaygafitness.com
Faith Journeys - Erma Mast, Kathy Falb, Phyllis Hannon & Nikki Broughton
In this episode of The Sunday Roast, recorded on Sunday 11th May, Phil Carroll, Kevin Hornsby, and Charles Archer return with a packed agenda as they unpack a truly historic week. From the Vatican to Washington, Westminster to Wall Street, there's no shortage of headlines. They begin with a landmark moment: the Catholic Church announces its first American-born Pope, Cardinal Robert Francis Prevost, now Pope Leo XIV, bringing a message of unity from the heart of St. Peter's Basilica. Across the Atlantic, Donald Trump's controversial proposal to reopen Alcatraz sparks debate, while a major US-UK trade deal reshapes the automotive and agricultural landscapes with sweeping tariff changes. On the home front, Labour's UK-India trade deal gets mired in political miscommunication despite clear economic benefits. VE Day 80 is commemorated across Britain, but not everyone pauses for reflection—Phil shares an amusing moment from the supermarket. In the markets, the team highlights this week's movers including Symphony Environmental, Mosman Oil and Gas, Surface Transforms, Empyrean Energy, and Mast Energy Developments—whose CEO Pieter Krügel joins for an exclusive update. They also discuss Conroy Gold's latest antimony discovery and Alien Metals' drilling progress at Elizabeth Hill. With central banks adjusting interest rates, gold and silver diverging, and AIM showing signs of revival, the team explores where smart money might be heading. In sport, McLaren's Oscar Piastri continues his winning streak in Miami, Arsenal crash out of the Champions League, and Manchester United set up a dramatic Europa League final showdown with Spurs. It's a week of firsts, flashpoints, and financial shifts—so tune in, pour yourself a coffee, and settle in for this edition of The Sunday Roast. 00:00 - 00:30:36 Weekly News Roundup 00:30:36 #SYM 00:30:59 #MSMN 00:31:09 #SCE 00:31:16 #EML 00:33:14 #TIR 00:34:01 #CGNR 00:40:20 #UFO 00:49:49 #MAST 00:56:07 #AGFX 00:56:23 #1SP Disclaimer & Declaration of Interest This podcast may contain paid promotions, including but not limited to sponsorships, endorsements, or affiliate partnerships. The information, investment views, and recommendations provided are for general informational purposes only and should not be construed as a solicitation to buy or sell any financial products related to the companies discussed. Any opinions or comments are made to the best of the knowledge and belief of the commentators; however, no responsibility is accepted for actions based on such opinions or comments. The commentators may or may not hold investments in the companies under discussion. Listeners are encouraged to perform their own research and consult with a licensed professional before making any financial decisions based on the content of this podcast.
durée : 00:24:55 - La tomate burrata revisitée par le chef Kevin Mast - Chef à domicile à Pau et environs, Kevin Mast transforme chaque événement en une expérience inoubliable. Grâce à ses menus sur mesure et à sa collaboration avec Aurélien, mixologue, il crée des accords mets-cocktails qui émerveillent les convives. Découvrez son parcours et ses projets à venir.
Acts 9:4-8 Guest Speakers: Clair Mast and Larry Wehr
In this episode of The Midweek Takeaway, we welcome back Pieter Krügel, CEO of Mast Energy Developments (MED), to discuss the company's latest milestones and strategic progress. Pieter shares insights on MED's recently completed £5 million investment agreement with Powertree, which fully funds its 7.5MW Hindlip project and signals the beginning of a long-term Growth Capital Partnership. We explore what this means for timelines, construction, and broader growth ambitions. The conversation also covers strong trading performance at the Pyebridge site, now delivering average monthly revenues of over £24,000 per MW, and the positive impact of clearing leveraged positions in the company's shares. As energy security concerns rise following blackouts in Spain and Portugal, we discuss the role of flexible power generation and the importance of grid inertia as the UK transitions toward a renewable-led energy system. Disclaimer & Declaration of Interest This podcast may contain paid promotions, including but not limited to sponsorships, endorsements, or affiliate partnerships. The information, investment views, and recommendations provided are for general informational purposes only and should not be construed as a solicitation to buy or sell any financial products related to the companies discussed. Any opinions or comments are made to the best of the knowledge and belief of the commentators; however, no responsibility is accepted for actions based on such opinions or comments. The commentators may or may not hold investments in the companies under discussion. Listeners are encouraged to perform their own research and consult with a licensed professional before making any financial decisions based on the content of this podcast.
In this Star Wars Day edition of The Sunday Roast, The lads return with a scorching hot rundown of the week's biggest stories, from geopolitical tremors to major market moves. We unpack the landmark U.S.-Ukraine Reconstruction Investment Fund agreement giving the U.S. preferential access to Ukraine's critical minerals—titanium, lithium, and rare earths—and explore the ripple effects across Europe, the West, and a sidelined Russia. We also dive into the dramatic ousting of U.S. National Security Adviser Mike Waltz following the jaw-dropping “Signalgate” scandal. This week's guest is Charles Bray, Executive Chairman of Aterian Plc, who joins us to discuss how geopolitical tensions and resource nationalism are reshaping the critical minerals landscape. We get the lowdown on Aterian's game-changing $4.5 million trade finance deal in Rwanda and their recent £468,000 convertible bond raise aimed at boosting exploration in Morocco, Botswana, and beyond. Plus, we revisit our “12 for 2025” watchlist with a progress check and updated outlook, and wrap up with all the movers and shakers making waves in the markets this week. May the 4th be with you! 00:00 - 00:06:48 Weekly News Roundup 00:06:48 #ATN Interview 00:41:16 12 for 25 stocks review 00:41:51 #POW 00:42:46 #GMET 00:44:29 #COBR 00:45:59 #GGP 00:47:20 #AMRQ 00:48:55 #GROC 00:50:48 #MAST 00:52:52 #RMR 00:55:41 #SVML 00:59:24 #BZT 01:00:58 #JLP 01:02:10 #PR1 01:06:06 #IMM 01:07:46 #ARS 01:09:13 #ATN 01:10:11 #TRAK 01:11:26 #BSFA 01:14:32 #EST 01:16:13 #AFP #XTR 01:16:29 #ARCM 01:16:46 #HEX 01:18:14 #MIRI 01:18:45 Ransomware attacks #MKS 01:28:46 TV Recommendation Disclaimer & Declaration of Interest This podcast may contain paid promotions, including but not limited to sponsorships, endorsements, or affiliate partnerships. The information, investment views, and recommendations provided are for general informational purposes only and should not be construed as a solicitation to buy or sell any financial products related to the companies discussed. Any opinions or comments are made to the best of the knowledge and belief of the commentators; however, no responsibility is accepted for actions based on such opinions or comments. The commentators may or may not hold investments in the companies under discussion. Listeners are encouraged to perform their own research and consult with a licensed professional before making any financial decisions based on the content of this podcast.
In this episode, we discuss the gut-immune axis and Small Intestinal Fungal Overgrowth (SIFO), with a mechanistic focus on immune activation and epithelial barrier disruption. We detail contributing factors to and symptoms of SIFO. We further discuss the anatomical positioning and immunological functions of mast cells within the lamina propria, highlighting mast cell activation syndrome, while detailing how SIFO and SIBO can serve as upstream triggers for mast cell activation.Topics:1. The Gut-Immune Axis and Mast Cells - The intestinal epithelium forms the innermost selective barrier, coated in a protective mucus layer.- Immediately beneath lies the lamina propria, rich in immune cells including mast cells. 2. Mast Cells in the Lamina Propria - Mast cells are positioned near nerves, capillaries, lymphatics, and epithelial cells within the lamina propria.- Their anatomical location enables rapid immune surveillance and inflammatory response.- Mast cell granules store histamine and more. 3. Mast Cell Mediators - Histamine: Biogenic amine, inflammatory signaling.- Tryptase: A serine protease.- Cytokines and lipid mediators also released upon activation. 4. Mast Cell Activation Syndrome (MCAS) - Systemic: skin, respiratory tract, cardiovascular system, nervous system, and more.- The gastrointestinal tract.- Common triggers for mast cell activation. 5. Transition to Small Intestinal Fungal Overgrowth (SIFO) - Overgrowth of fungal organisms, often candida species, within the small intestine.- Contributing factors including hypochlorhydria, slowed motility, immune suppression, disrupted bacterial populations.- Overlap: SIFO, SIBO 6. Hypochlorhydria and the Stomach's Defense Role - Parietal cells secrete hydrochloric acid (HCl) and intrinsic factor.- HCl denatures proteins and sterilizes ingested pathogens.- Chief cells secrete pepsinogen, which becomes pepsin in acidic conditions to digest proteins.- Consequences of Reduced Gastric Acidity 7. The Role of Intestinal Motility - Enteric nervous system (ENS), myenteric and submucosal plexuses.- Coordinated contractions preventing stasis and microbial overgrowth. 8. Common Symptoms of SIFO and clinical overlap with SIBO 9. Candida and Fungal Pathophysiology in the Gut - Yeast form, regulated by microbial competition and immune defenses.- Hyphal transformation.- Degrade the mucus layer, disrupt epithelial integrity, trigger inflammation. 10. Secretory IgA and Mucosal Defense - Chronic stress, immune dysfunction, dysbiosis can lower sIgA levels and weaken mucosal immunity. 11. SIFO, SIBO, and Mast Cell Activation 12. Conclusion - Root cause approach, multi-factorial Thanks for tuning in!Get Chloe's Book Today! "75 Gut-Healing Strategies & Biohacks" Follow Chloe on Instagram @synthesisofwellnessFollow Chloe on TikTok @chloe_c_porterVisit synthesisofwellness.com to purchase products, subscribe to our mailing list, and more!
Host Finis Stribling IV talks about passions, cultures, and more with Noah Mast.Sponsored by: Final Form Supplements High quality supplements for everyone, whether you are a hardcore gym rat needing gains, a couch potato that just wants some multivitamins, or somewhere in between we got what you need.FinalFormSupps.com
The Discovery, Titanic, BYU—all began with a dream. We must nail our colors to the mast to ensure the safety and success of our ship. Click here to see the speech page.See omnystudio.com/listener for privacy information.
Jonathan Mast stands at the forefront of AI prompting mastery, empowering businesses and entrepreneurs to leverage artificial intelligence for measurable growth. Since 1995, he has blended marketing expertise with cutting-edge technology, and over the past few years has emerged as a leading authority on practical AI implementation.With an engaged audience of nearly 500,000 AI enthusiasts and entrepreneurs (350,000+ in his active Facebook group and 100,000+ email subscribers), Jonathan is a trusted voice making complex AI concepts approachable and immediately applicable. His Perfect Prompting Framework teaches businesses how to effectively communicate with AI tools like ChatGPT, Claude, and Gemini to achieve exceptional results.As the founder of White Beard Strategies, Jonathan focuses on helping businesses and their teams leverage AI to save time, increase profits, and deliver more value to their audiences. His philosophy emphasizes AI as a tool that amplifies skill and experience rather than replacing human creativity and judgment.Jonathan's dynamic speaking style breaks down complex AI concepts into actionable steps that audiences can implement immediately. His international speaking engagements across North America, Asia, and Australia are packed with practical takeaways, and his 100+ podcast appearances demonstrate his ability to connect with and educate diverse audiences. AI Prompting Mastery: How to use AI to streamline operations, enhance marketing, and drive business growthPractical AI Implementation: The “One More Thing” approach to sustainably integrate AI into daily business operationsAI Tool Selection Strategy: Focusing on foundational tools rather than chasing niche applicationsBusiness Transformation with AI: Real-world strategies for saving time, increasing profits, and delivering exceptional valueEthical AI Integration: Responsibly leveraging AI while maintaining authenticity and human connection“Jonathan Mast is a wizard!
Summary In this episode of the Future of Dermatology Podcast, we revisit the 2024 SF Derm Society's Annual Conference where Dr. Jason Hawkes discusses the complexities of urticaria, including its definitions, types, and the role of mast cells in the condition. This presentation highlights the differences between acute and chronic urticaria, the importance of understanding autoimmunity in relation to urticaria, and the latest treatment approaches, including innovative therapies like Omalizumab. The episode concludes with a call to action for dermatologists to embrace the treatment of urticaria and engage with their patients effectively. Takeaways - Urticaria is often misunderstood, but it has exciting aspects to explore. - Acute urticaria lasts less than six weeks, while chronic urticaria lasts longer. - Chronic spontaneous urticaria (CSU) is often idiopathic and can last for years. - Mast cells play a central role in the pathophysiology of urticaria. - Autoimmunity is a common theme in patients with urticaria, especially in women. - Diagnosis of urticaria is primarily clinical, with no specific lab tests required. - Many patients do not respond to standard antihistamine treatments. - Omalizumab is a powerful treatment option for chronic urticaria. - Anaphylaxis is rare in patients treated with Omalizumab for urticaria. - Dermatologists should feel confident in treating urticaria with available therapies. Chapters 00:00 - Introduction to the Future of Dermatology Podcast 00:57 - Understanding Urticaria: Definitions and Types 03:50 - Differentiating Acute and Chronic Urticaria 06:13 - The Role of Mast Cells in Urticaria 09:03 - Autoimmunity and Urticaria: Comorbidities and Testing 10:59 - Diagnosis and Treatment Approaches for Urticaria 13:52 - Innovative Therapies: Omalizumab and Beyond 15:42 - Conclusion and Call to Action
In this encore episode, we discuss the role of histamine within the gastrointestinal tract, detailing its regulation of gastric acid secretion and impact on intestinal motility. We examine how histamine-producing enterochromaffin-like (ECL) cells, mast cells, and gut microbiota contribute to histaminergic signaling, and how enzymatic degradation via diamine oxidase (DAO) maintains homeostasis. Additionally, we discuss histamine intolerance, highlighting the impacts of dysbiosis (as well as SIBO or small intestinal bacterial overgrowth) and intestinal barrier dysfunction on DAO insufficiency and histamine accumulation.Topics: 1. Introduction to Histamine & the Gastrointestinal Tract- Role in digestion and motility- Impact of intestinal conditions such as SIBO 2. Histamine as a Biogenic Amine- Definition and classification- L-histidine and histidine decarboxylase (HDC)- Presence in various tissues, including the GI tract 3. Sources of Histamine in the Gut- Enterochromaffin-like (ECL) cells in the stomach- Mast cells in the lamina propria- Histamine-producing gut bacteria 4. Histamine's Role in Digestion & Gastric Acid Secretion- Interaction with parietal cells in the stomach- Activation of proton pumps via H₂ receptor binding- Maintenance of acidic pH for digestion- Importance of proper pH within the stomach for protecting against pathogenic microbes- Impact on downstream gut microbiota balance (e.g., SIBO) 5. Histamine & Intestinal Motility- Modulation of gut motility via H₁ and H₃ receptors- H₁ receptor activation leading to contractions (diarrhea, cramping)- H₃ receptor-mediated inhibition of neurotransmitter release (bloating, slow motility) 6. Histamine Intolerance: Definition & Mechanisms- Diamine Oxidase and histamine breakdown- DAO secretion by enterocytes (intestinal epithelial cells)- Enzymatic breakdown of histamine before absorption 7. Factors That Can Affect DAO Activity- Genetic Polymorphisms: AOC1 gene, reduced DAO expression- Cofactor Deficiencies: Copper, vitamin B6, and vitamin C as essential DAO cofactors- Importance of intestinal lining integrity for DAO production- Conditions leading to or associated with enterocyte damage- Intestinal dysbiosis and histamine accumulation- Intestinal dysbiosis & epithelial/enterocyte damage- Suppression of DAO production due to epithelial dysfunction- Small Intestinal Bacterial Overgrowth (SIBO) & Histamine 8. Symptoms of Histamine Intolerance- Gastrointestinal symptoms (bloating, gas, constipation, diarrhea, acid reflux...)- Systemic symptoms (dizziness, flushing, migraines...) 9. Identifying Potential Root Causes- Tools and supplements- Bioindividual approachThanks for tuning in!Get Chloe's Book Today! "75 Gut-Healing Strategies & Biohacks" Follow Chloe on Instagram @synthesisofwellnessFollow Chloe on TikTok @chloe_c_porterVisit synthesisofwellness.com to purchase products, subscribe to our mailing list, and more!
Mike and Charles postmortem the NCAA Men's and Women's Basketball Tournaments, Ovi makes history, Luka goes homemade coaching your team to the playoffs gets you fired. Jason's Wormbyte on "A Tradition Like No Other" and the Dr. Smith Sports Moment of the Week.
Dale and LuAnne Mast share how God unlocked King David's calling through identity and faith, with insights from the book “And David Perceived He was King.” (J2609)
Adventure: Lux Radio Theater “Two Years Before the Mast” 9/22/47 CBS.
The past few years have been a rollercoaster of hard lessons learned, creativity, and pivots. In this episode, we're peeling back the curtain with Krissy Mast, sharing her struggles with creative burnout after building a 7-figure design business and how she redefined success by deciding to close the doors and start fresh. From the projects that lit her up to the ones that drained her, Krissy gets REAL about what it means to build a sustainable creative business (again). We'll also talk about the importance of setting boundaries, why saying “no” can be a superpower, and how we're rethinking how we approach client work vs. personal passion projects. Plus, we dive deep into art licensing, how it works, why it can be a game-changer for artists, and what we've learned from our experiences. If you've ever wondered how to monetize your art beyond commissions and client work, this conversation is for you.All that and more when you listen to this episode:What led to creative burnout and how Krissy managed itHow setting boundaries helped reclaim our creativityThe myth of constant hustle–and why we're challenging it Balancing client work with personal projects What you need to know about art licensing and passive income opportunities for artistsHow we approach licensing deals and what to watch out forWorking with art agents and why it might be right for youHow outreach can build confidence and lead to more clients for your art business Mentioned in this episode:Stacie Bloomfield Liz Kohler BrownJewel (art agent)Art Licensing BlueprintSkillshareConnect with our guest: Krissy Mast on Instagram | Website | Facebook GroupConnect with Katie & Ilana from Goodtype Goodtype Website Goodtype on Instagram Goodtype on Youtube Love The Typecast and free stuff? Leave a review, and send a screenshot of it to us on Slack. Each month we pick a random reviewer to win a Goodtype Goodie! Goodies include merch, courses and Kernference tickets! Leave us a review on Apple PodcastsSubscribe to the showTag us on Instagram @GoodtypeFollow us on Tiktok @lovegoodtypeLearn from Katie and IlanaGrab your tea, coffee, or drink of choice, kick back, and let's get down to business!
Major Joshua Mast, a U.S. Marine Corps officer, gained attention for his efforts to adopt an Afghan war orphan. Mast initiated adoption proceedings for a baby girl found on an Afghan battlefield in 2019. His actions, motivated by a desire to ensure the child's safety, led to a complex legal battle involving the Department of Justice, the State Department, and Afghan relatives. In October 2024, a military board substantiated misconduct allegations against Mast but declined to separate him from service. The board found that while Mast acted in a way “unbecoming an officer”, his actions did not warrant dismissal from the Marine Corps. Mast, now 41 and living in Hampstead, North Carolina with his wife Stephanie, continues to advocate for the child's well-being. Shawn Ryan Show Sponsors: http://helixsleep.com/srs http://amac.us/srs http://meetfabric.com/srs http://preparewithshawn.com This episode is sponsored by BetterHelp. Give online therapy a try at betterhelp.com/srs and get on your way to being your best self. Please leave us a review on Apple & Spotify Podcasts. Vigilance Elite/Shawn Ryan Links: Website | Patreon | TikTok | Instagram | Download Learn more about your ad choices. Visit podcastchoices.com/adchoices
A 5-year-old sits at the heart of an international controversy involving Al-Qaeda, the Taliban, the U.S. State Department, and even Hunter Biden's law firm. In what Glenn describes as maybe his “most important” episode of "The Glenn Beck Podcast" yet, Stephanie and Joshua Mast detail the unbelievable story of rescuing an injured infant from the war in Afghanistan and their uphill battle to bring her safely to America during the disastrous Afghanistan withdrawal under President Biden's administration. Now, their 5-year-old daughter's fate again hangs in the balance, and she is just days away from a Virginia court case that may change her life forever. The Mast family believes their daughter is the biological child of foreign fighters. If they're correct, then her mere existence unravels the foundations of the peace agreement between the U.S. and Afghanistan, which stipulated that there were NO foreign fighters in Afghanistan. In a tangled web of motivations, Glenn is shocked by the possibility that the U.S. State Department may have placed a baby girl in the hands of people without any evidence of biological relations and with potential ties to the Taliban. The Masts make a public plea to the Trump administration to save their little girl from a custody battle with international implications but deeply personal ramifications for this little girl. GLENN'S SPONSORS Relief Factor Relief Factor can help you live pain-free! The three-week quick start is only $19.95. Visit https://www.relieffactor.com/ or call 800-4-RELIEF. Jase Medical Care for yourself and loved ones when the unexpected happens. Go to https://jasemedical.com/ and use code BECK10 at checkout for a discount. Real Estate Agents I Trust When you're buying or selling a home, you need a real estate agent you can trust. Visit https://realestateagentsitrust.com/ to find the top-selling real estate agents in your area. Learn more about your ad choices. Visit megaphone.fm/adchoices