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In this episode of Talking Sleep, host Dr. Seema Khosla welcomes three members of the World Sleep Society's consumer health technology task force—Dr. Michael Chee, Professor and Director of the Center for Sleep and Cognition at the National University of Singapore who chaired the guideline-writing task force; Dr. Mathias Baumert, an associate professor leading the biomedical engineering discipline of the school of Electrical and Mechanical engineering at Adelaide University in Australia, and Dr. Cathy Goldstein, professor of neurology at the University of Michigan. to discuss their global recommendations for the use of consumer sleep technology and wearable health trackers. Consumer wearables have become ubiquitous in clinical practice, with patients routinely sharing device data. While some clinicians have historically dismissed this information, attitudes are shifting as technology improves and rigorous research examines sensors, algorithms, and data quality. Dr. Chee explains that the recommendations are designed for multiple audiences: end-users, clinicians, researchers, and manufacturers, with specific guidance for each group. The conversation addresses practical considerations: the assumption that users have good perfusion, how bed partners can influence movement detection, and the fundamental truth that the best device is one patients will actually wear properly. The panel discusses recent FDA regulatory changes and clarifies whether guidance applies only to non-FDA cleared wellness devices or has broader implications. The experts systematically review various metrics from wearables. They introduce TATS (total attempted time in sleep) and explain what clinicians should know about sleep onset and offset detection. The episode emphasizes the call for standardized Fundamental Sleep Measures and greater transparency about test populations used in device validation. Dr. Baumert discusses the need to co-create benchmarks for measurement accuracy across different contexts—from persons with normal sleep to shift workers to those with sleep disorders. Whether you're skeptical about consumer wearables or seeking guidance on interpreting patient-generated data, this episode provides evidence-based recommendations for moving forward responsibly. Join us for this important discussion about embracing consumer sleep technology while maintaining clinical rigor.
Is it true that there is no cognition in the ecological approach to skill? No, of course not. In this episode, I want to start a series of episodes to explain how we can understand cognition (e.g., problem solving, memory, intention, agency, anticipation, decision making, etc) from an ecological viewpoint. Articles:The ecological dynamics of cognizant action in sport http://perceptionaction.com/ My Research Gate Page (pdfs of my articles) My ASU Web page Podcast Facebook page (videos, pics, etc) Subscribe in iOS/Apple Subscribe in Anroid/Google Support the podcast and receive bonus content Credits: The Flamin' Groovies – ShakeSome Action Mark Lanegan - Saint Louis Elegy via freemusicarchive.org and jamendo.com
Walking 5,001 to 7,500 steps a day slows the buildup of tau, the brain protein linked to Alzheimer's-related decline, helping you stay sharper for years longer Older adults with elevated amyloid — a key early Alzheimer's marker — preserved memory and daily function far better when they consistently reached a moderate step range Even small increases in movement, such as moving from under 3,000 steps to 3,500 to 5,000 per day, deliver meaningful cognitive benefits without requiring intense exercise High-intensity training pushed healthy adults into metabolic dysfunction, reducing mitochondrial energy production by about 40% and disrupting blood sugar stability Finding your personal exercise "sweet spot" — enough movement to avoid inactivity without pushing into extreme training — protects both long-term brain health and daily metabolic balance
What if neurons aren't the foundation of mind? In this Mind-Body Solution Colloquia, Michael Levin and Robert Chis-Ciure challenge one of neuroscience's deepest assumptions: that cognition and intelligence are exclusive to brains and neurons.Drawing on cutting-edge work in bioelectricity, developmental biology, and philosophy of mind, this conversation explores how cells, tissues, and living systems exhibit goal-directed behavior, memory, and problem-solving — long before neurons ever appear.We explore: • Cognition without neurons• Bioelectric networks as control systems• Memory and learning beyond synapses• Morphogenesis as collective intelligence• Implications for AI, consciousness, and ethicsThis episode pushes neuroscience beyond the neuron, toward a deeper understanding of mind, life, and intelligence as continuous across scales.TIMESTAMPS:0:00 – Introduction: Why Neuroscience Must Go Beyond Neurons3:12 – The Central Claim: Cognition Is Not Exclusive to Brains7:05 – Defining Cognition, Intelligence, and Agency Without Neurons11:02 – Bioelectricity as a Control Layer for Morphogenesis15:08 – Cells as Problem-Solvers: Goals, Memory, and Error Correction19:41 – The Body as a Cognitive System: Scaling Intelligence Across Levels24:10 – Developmental Plasticity and Non-Neural Decision-Making28:36 – Morphological Computation and Collective Cellular Intelligence33:02 – Challenging Neuron-Centric Neuroscience Assumptions37:18 – Bioelectric Networks vs Neural Networks: Key Differences41:55 – Memory Without Synapses: Storing Information in Living Tissue46:07 – Rewriting Anatomy: Regeneration, Repatterning, and Control50:29 – Cancer, Developmental Errors, and Cognitive Breakdown54:48 – Pluribus: Philosophical Implications59:14 – From Cells to Selves: Where Does Agency Begin?1:03:22 – Implications for AI: Intelligence Without Brains or Neurons1:08:11 – Rethinking Consciousness: Gradualism vs Binary Models1:12:47 – Ethics of Expanding the Moral Circle Beyond Humans1:17:31 – Future Science: New Tools for a Post-Neuron Neuroscience1:22:54 – Closing Reflections: Life, Mind, and Intelligence All the Way DownEPISODE LINKS:- Cognition All the Way Down 2.0: Neuroscience Beyond Neurons in the Diverse Intelligence Era: https://link.springer.com/article/10.1007/s11229-025-05319-6- Robert's Publications: https://scholar.google.com/citations?user=7V9C7skAAAAJ&hl=en- Mike's Podcast 1: https://www.youtube.com/watch?v=v6gp-ORTBlU- Mike's Podcast 2: https://www.youtube.com/watch?v=kMxTS7eKkNM- Mike's Podcast 3: https://www.youtube.com/watch?v=1R-tdscgxu4- Mike's Podcast 4 (with Terrence Deacon): https://youtu.be/HuWbHwPZd60?si=z2unvX37OjXMjjIv- Mike's Lecture: https://www.youtube.com/watch?v=aQEX-twenkA- Mike's Channel: https://www.youtube.com/@drmichaellevin- Mike's Website: https://drmichaellevin.org/- Mike's Blog: https://thoughtforms.lifeCONNECT:- Website: https://mindbodysolution.org - YouTube: https://youtube.com/@mindbodysolution- Podcast: https://creators.spotify.com/pod/show/mindbodysolution- Twitter: https://twitter.com/drtevinnaidu- Facebook: https://facebook.com/drtevinnaidu - Instagram: https://instagram.com/drtevinnaidu- LinkedIn: https://linkedin.com/in/drtevinnaidu- Website: https://tevinnaidu.com=============================Disclaimer: The information provided on this channel is for educational purposes only. The content is shared in the spirit of open discourse and does not constitute, nor does it substitute, professional or medical advice. We do not accept any liability for any loss or damage incurred from you acting or not acting as a result of listening/watching any of our contents. You acknowledge that you use the information provided at your own risk. Listeners/viewers are advised to conduct their own research and consult with their own experts in the respective fields.
In this episode of the Ageless Future Podcast, host Cade Archibald sits down with Derek Norsworthy, CEO of NeuroCatch, to explore a breakthrough approach to cognitive assessment using objective “brain vital signs.” Derek shares how NeuroCatch evolved from decades of neuroscience research into a point-of-care tool designed to measure cognitive function with lab-level sensitivity—helping clinicians move beyond subjective questionnaires and “you seem fine” evaluations. Together, they discuss how NeuroCatch is used to establish baseline brain performance, track improvements from longevity and brain-optimization protocols (including peptides, stem cells, HBOT, red light, and other interventions), and detect subclinical cognitive changes that may not appear on MRI/CT or standard assessments. Derek also recounts his personal health journey from burnout and hormone disruption to functional medicine recovery, reinforcing the episode's theme: better outcomes happen when innovative technology and integrative care meet in the middle. Derek Norsworthy: I began my career as a clinical professional and evolved into a recognized leader in healthcare technology, specializing in the integration of electronic health record systems and innovation across large U.S. health systems. Through roles as a strategic advisor, business consultant, and healthcare entrepreneur, I've guided organizations in adopting advanced technologies to improve clinical workflows, operations, and patient outcomes. Now serving as CEO of HealthtechConnex, I bring my clinical experience and passion for innovation full circle to help bring cutting-edge health technologies to market. Beyond healthcare, I'm a husband, father, endurance athlete, leadership coach, and technology entrepreneur, driven by a mission to inspire others with the tools, mindset, and confidence to live life fully.LIKE/FOLLOW/SUBSCRIBE DEREK:LinkedIn: https://www.linkedin.com/in/derek-norsworthy-88427530b/LIKE/FOLLOW/SUBSCRIBE AGELESS FUTURE:YouTube -https://www.youtube.com/@ReganArchibald / https://www.youtube.com/@Ageless.FutureLinkedIn: https://www.linkedin.com/in/regan-archibald-ab70b813Instagram: https://www.instagram.com/ageless.future/Facebook: https://www.facebook.com/AgelessFutureHealth/AGELESS FUTURE RESOURCES:Book Comprehensive Labs: https://agelessfuture.com/longevity-labs/FREE copy of The Peptide Blueprint: https://agelessfuture.com/blueprintSign up for future Health Accelerator Challenges calls LIVE! https://us02web.zoom.us/webinar/register/WN_YZsiUMOzSyqcE8IinC5YEQ#/registrationBooks: https://www.amazon.com/Books-Regan-Archibald/s?rh=n%3A283155%2Cp_27%3ARegan%2BArchibaldArticles: https://medium.com/search?q=Regan+ArchibaldDISCLAIMER: This video is for educational purposes only and does not provide medical advice, diagnosis, or treatment. Many of the molecules discussed in this video are research compounds and are not approved by the U.S. Food and Drug Administration (FDA) for any specific medical use, indication, or condition. They are mentioned only in the context of existing scientific literature and ongoing research and are not being recommended, prescribed, sold, or offered through this video. This content does not endorse or recommend any specific tests, products, procedures, or treatment protocols.References to our clinic are for general educational context only; investigational or non‑approved products are not available for direct ordering or prescribing based solely on viewing this content. Do not start, stop, or change any medication, peptide, or supplement based on this video. All medical decisions must be made with a licensed prescribing clinician after a proper evaluation. No provider–patient relationship is created by viewing this content or contacting our clinic. Regan Archibald is a Licensed Acupuncturist and longevity coach. He is not a medical doctor. Cade Archibald is COO and Co-Founder of Ageless Future, also not a medical doctor. All medical decisions, lab ordering, and prescribing in our clinic are performed only by our licensed medical team (MD, APRN, PA). Viewers should follow the guidance of their own licensed clinicians and local health authorities regarding diagnosis and treatment decisions.
Dr. Michael Levin (@drmichaellevin) is the Vannevar Bush Distinguished Professor of Biology at Tufts University and director of the Allen Discovery Center. He is primarily interested in how intelligence self-organizes in a diverse range of natural, engineered, and hybrid embodiments. Applied to the collective intelligence of cell groups undergoing morphogenesis, these ideas have allowed the Levin Lab to develop new applications in birth defects, organ regeneration, and cancer suppression.This episode is brought to you by:ShipStation shipping software: ShipStation.com/TimAG1 all-in-one nutritional supplement: DrinkAG1.com/TimOur Place's Titanium Always Pan® Pro using nonstick technology that's coating-free and made without PFAS, otherwise known as “forever chemicals”: FromOurPlace.com/TimTIMESTAMPS:[00:00:00] Start[00:03:18] The Body Electric: A Vancouver bookstore discovery that launched a career.[00:04:19] Bioelectricity 101: Your brain uses it to think; your body used it before you had a brain.[00:06:05] The lesson learned by scrambled tadpole faces that rearrange themselves.[00:08:51] Software vs. hardware: The genome is your factory settings, not your destiny.[00:11:43] Two-headed flatworms: Rewriting biological memory without touching DNA.[00:16:20] Seeing memories: Voltage-sensitive dyes reveal the body's hidden blueprints.[00:20:12] Three killer apps for humans: Birth defects, regeneration, and cancer.[00:24:27] Cancer as identity crisis: Cells forgetting they're part of a team.[00:25:40] The boredom theory of aging: Goal-seeking systems with nothing left to do.[00:30:09] Planaria's immortality hack: Rip yourself in half every two weeks.[00:31:27] Manhattan Project for aging: Crack cellular cognition, everything else falls into place.[00:33:47] Giving cells new goals: Convince a gut to become an eye.[00:37:42] Must mammalian mortality be mandatory?[00:40:25] Cross-pollination: Why biologists would benefit from programming courses.[00:47:15] Does acupuncture actually do anything?[00:50:57] Placebo as feature, not bug: Words and drugs share the same mechanism.[00:55:06] The frame problem: Why robots explode and rats intuit what matters.[00:59:41] Binary thinking is a trap: “Is it intelligent?” is the wrong question.[01:07:46] Minimal brain, normal IQ: Clinical cases that break neuroscience.[01:08:45] Super panpsychism: Your liver might have opinions.[01:13:48] The Platonic space: Bodies as thin clients for patterns from elsewhere.[01:15:24] Keep asking “why” and you end up in the math department.[01:23:07] Polycomputing: Sorting algorithms secretly doing side quests.[01:28:24] Power scaling for the future and avoiding red herrings for understanding machine minds.[01:34:06] Sci-fi recommendations.[01:37:24] Cliff Tabin's toast and Dan Dennett's steel manning.[01:41:21] Parting thoughts.*For show notes and past guests on The Tim Ferriss Show, please visit tim.blog/podcast.For deals from sponsors of The Tim Ferriss Show, please visit tim.blog/podcast-sponsorsSign up for Tim's email newsletter (5-Bullet Friday) at tim.blog/friday.For transcripts of episodes, go to tim.blog/transcripts.Discover Tim's books: tim.blog/books.Follow Tim:Twitter: twitter.com/tferriss Instagram: instagram.com/timferrissYouTube: youtube.com/timferrissFacebook: facebook.com/timferriss LinkedIn: linkedin.com/in/timferrissSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Cognition and the Science of Non-Invasive Brain Stimulation in MS – Episode 196 Cognitive changes in MS are often misunderstood. In this episode, Stephanie talks with Dr. Leigh Charvet about what cognition in MS really looks like—why processing speed, not memory loss, is the most common challenge, and why symptoms can fluctuate day to day. They break down what non-invasive brain stimulators are, how it boosts the effects of cognitive rehab, and what research shows about its impact on cognition, fatigue, cannabis use, and depression in people with MS. Disclaimer: This podcast provides general educational information. Can Do MS does not endorse, promote, or recommend any product or service associated with the content of this program
In this episode of Spotlight on Care, hosts Virginia Naeve and Steve O'Leary are joined by Deborah Kan, the founder of Being Patient , a leading digital resource for Alzheimer's and dementia information. Drawing from her personal experience as a caregiver and her background as a journalist, Deborah explains how her platform serves as a comprehensive roadmap for families through three core pillars: demystifying complex research, hosting live "Brain Talks" with medical experts, and sharing authentic first-person stories to reduce stigma. The conversation also explores innovative tools available on the site, such as interactive diagnostic guides and AI-powered "Care Bots" designed to provide immediate support.To learn more about Being Patient and access these resources, click on this link here: https://beingpatient.com/.Send us a text
In this Huberman Lab Essentials episode, my guest is Dr. Wendy Suzuki, PhD, a professor of neural science and psychology at New York University. We discuss simple, daily habits to improve focus, memory and overall cognitive performance. Dr. Suzuki explains how exercise directly enhances brain function—both the immediate benefits of a single workout and long-term support for cognitive health. We also discuss how meditation, verbal affirmations, sleep and other behavioral practices positively influence mood and stress regulation. Episode show notes: https://go.hubermanlab.com/7gTmlIR Join the Huberman Lab Neural Network Newsletter: https://www.hubermanlab.com/newsletter Thank you to our sponsors AG1: https://drinkag1.com/huberman BetterHelp: https://betterhelp.com/huberman Eight Sleep: https://eightsleep.com/huberman Timestamps (00:00:00) Wendy Suzuki (00:00:21) What Makes Moments Memorable? (00:02:24) Memory & Hippocampus, Imagination (00:05:35) Sponsor: BetterHelp (00:06:37) One-Trial Learning, Fear (00:08:10) Exercise Effects on Focus, Attention & Memory (00:12:31) Brain-Derived Neurotrophic Factor (BDNF) & Exercise (00:15:10) Sponsor: AG1 (00:16:55) Tools: Cardiovascular Exercise; 10-Minute Walk & Mood (00:18:43) How Exercise Increases BDNF (00:20:47) Adults, Neuron Growth, Hippocampus (00:22:51) Exercise Effects on Memory, Tool: Morning Exercise (00:26:08) Exercise & Long-term Effects on Cognition, Older Adults (00:27:56) Minimum Exercise For Cognitive Benefits (Adults, 30s-50s) (00:32:03) Sponsor: Eight Sleep (00:33:22) Increase Exercise For Greater Cognitive Benefits (00:35:30) Affirmations, Exercise, Mood, IntenSati (00:37:37) Meditation & Benefits, Tool: Brief Meditation (00:39:32) Tools to Improve Attention Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices
We've got @GigiYoung back to talk a little bit about what may be on tap for humanity in 2026, along with a few other big topics. First, what value does the concept of 'Might Makes Right' hold for us? Is it incumbent upon us to re-pair might with morality in order to save the West? I would also like to revisit the topic of Free Will, and how it relates to things like Pre-Cognition. Should be a great first hour, and then I need to make time for calls in the second half because the topics are rich and it has been too long since we were able to get a proper open lines segment in! Unleash Your Brain w/ Keto Brainz Nootropic 15% OFF w/ code JANUARY: https://tinyurl.com/2cess6y7 And a FREE BAG of Creatine with Orders over $100 E-Mail to Request for FREE SAMPLES! Sponsor Monthly for VIP Perks: https://www.quitefrankly.tv/sponsor One-Time Tip: http://www.paypal.me/QuiteFranklyLive Quite Frankly Amazon Storefront: https://amazon.com/shop/quitefranklyofficial Official Coffee & Mugs: https://www.coffeerevolution.shop/category/quite-frankly Official QF MERCH: https://tinyurl.com/f3kbkr4s Gold & Silver: https://quitefrankly.gold Send Holiday cards, Letters, and other small gifts, to the Quite Frankly P.O. Box! Quite Frankly 222 Purchase Street, #105 Rye, NY, 10580 Tip in Crypto: BTC: bc1q97w5aazjf7pjjl50n42kdmj9pqyn5zndwh3lng XRP: rnES2vQV6d2jLpavzf7y97XD4AfK1MjePu Quite Frankly Socials: Twitter/X: @QuiteFranklyTV Instagram: @QuiteFranklyOfficial Discord Chat: https://discord.gg/xPu7YEXXRY Official Forum: https://tinyurl.com/k89p88s8 Telegram: https://t.me/quitefranklytv Streaming Live On: QuiteFrankly.tv (Powered by Foxhole) Youtube: https://tinyurl.com/yc2cn395 Rumble: https://tinyurl.com/yeytwwyz Kick: https://kick.com/quitefranklytv Twitch: https://www.twitch.tv/quitefranklylive Audio On Demand: Spotify: https://spoti.fi/301gcES iTunes: http://apple.co/2dMURMq SoundCloud: https://tinyurl.com/yc44m474
In this groundbreaking episode, I sit down with John Grey, a law enforcement K9 handler who's doing the "impossible" - running a program with PUPPIES that are BOTH therapy dogs AND detection dogs (firearms/explosives).The traditional K9 world said this would never work:❌ "Puppies have too high a washout rate"❌ "Therapy dogs are low-drive couch potatoes"❌ "Labs can't detect anything"❌ "You can't do both - pick one"John's program is proving all of that WRONG.What We Cover:Why their puppy washout rate is LOWER than agencies buying adult dogsHow therapy work actually IMPROVES detection capabilityTraining while working (no pulling officers off the road)The massive PR and funding benefits agencies don't expectUsing rituals and signals to switch between therapy and detection modesWhy "crackhead" high-drive dogs are actually HARDER to work withHow obedience training makes detection dogs betterWorking in elementary through high schoolsAdding tracking to the mix (and the lessons learned)Why this ISN'T entrapment (they're NOT drug dogs)Real Results:✅ Lower washout rates than traditional programs✅ Enormous public support and funding✅ Dogs work effectively in both roles✅ Handlers train while maintaining regular SRO duties✅ Kids and community fully invested in the dogsJohn's agency is in Colorado, and they're working with organizations like Colorado Police K9 Association who now offer therapy dog certification. His company is Fundamentals First K9 Training and he's helping other agencies implement similar programs.This episode challenges EVERYTHING traditional K9 programs believe about drive, selection, training timelines, and what's "possible" with working dogs.Whether you're in law enforcement, education, or just love working dogs, this conversation will change how you think about K9 programs.
Today, I am thrilled to connect with Dr. Kellyann Niotis, a fellowship-trained preventive neurologist specializing in risk reduction strategies for neurodegenerative disorders. Dr. Niotis completed her medical internship and neurology residency at New York-Presbyterian Weill Cornell Medical Center. She is passionate about preventive neurology, especially as it relates to advocacy, policy changes, and improving access to care and education. In our discussion, we explore the memory changes and brain fog that occur during perimenopause, and the fear of neurocognitive changes. We look at screening, testing, and labs, examine the effects of alcohol on brain health, and how estrogen is often framed as a reproductive hormone despite its role as a brain fuel regulator. We also clarify why caring for ourselves in midlife is essential for our long-term brain health, outlining the risk factors for neurocognitive changes, the role of neuroplasticity, and how lifestyle factors and loneliness collectively impact brain health and longevity. This is an exciting and evolving area of neurology, and I am truly grateful to share Dr. Niotis's expertise and insights with the Everyday Wellness community. IN THIS EPISODE, YOU WILL LEARN: How hormone fluctuations in perimenopause impact women's cognition and brain function The early signs that can help us distinguish menopausal cognitive changes from age-related decline or Alzheimer's How sleep quality (not just duration) profoundly affects neurocognitive health How vascular health and cholesterol influence long-term risk for cognitive decline and dementia How neuroplasticity and lifestyle interventions can support ongoing brain adaptation Why hearing loss is a major, under-recognized modifiable risk factor for dementia The value of exercise, especially high-intensity interval training, for growing new brain cells How estrogen and progesterone affect women's brain health Why too much data tracking can harm your brain health Connect with Cynthia Thurlow Follow on X, Instagram & LinkedIn Check out Cynthia's website Submit your questions to support@cynthiathurlow.com Join other like-minded women in a supportive, nurturing community: The Midlife Pause/Cynthia Thurlow Cynthia's Menopause Gut Book is on presale now! Cynthia's Intermittent Fasting Transformation Book The Midlife Pause Supplement Line Connect with Kellyann Niotis Instagram Website
On this episode of Vitality Radio, Jared launches a new series called Extraordinary Herbs, starting with one of the most widely used—and misunderstood—herbs today: ashwagandha. You'll learn how to use ashwagandha effectively in the real world, why extract type matters, how the most popular forms differ, and what actually determines results for different people. Jared breaks down what modern human research shows, as well as how this herb was traditionally used. Often labeled as the “de-stress herb,” ashwagandha shines as so much more! It supports healthy cortisol signaling, influencing sleep quality, hormone balance, exercise recovery, cognitive function, immune resilience, and thyroid health through the HPA axis. This episode breaks it all down without hype or confusion. Products:Sensoril AshwagandhaVital SleepAnxiety ReleaseMan Up!Man Up! Vital Test10 Days of SunshineNightburnVisit the podcast website here: VitalityRadio.comYou can follow @vitalitynutritionbountiful and @vitalityradio on Instagram, or Vitality Radio and Vitality Nutrition on Facebook. Join us also in the Vitality Radio Podcast Listener Community on Facebook. Shop the products that Jared mentions at vitalitynutrition.com. Let us know your thoughts about this episode using the hashtag #vitalityradio and please rate and review us on Apple Podcasts. Thank you!Just a reminder that this podcast is for educational purposes only. The FDA has not evaluated the podcast. The information is not intended to diagnose, treat, cure, or prevent any disease. The advice given is not intended to replace the advice of your medical professional.
It's an interesting question. Even more intriguing is why you believe what you do — and whether you live near a city.
Dr. Dominic D'Agostino (@DominicDAgosti2) is a tenured associate professor in the Department of Molecular Pharmacology and Physiology at the University of South Florida Morsani College of Medicine and a Visiting Senior Research Scientist at the Institute for Human and Machine Cognition.This episode is brought to you by:Gusto simple and easy payroll, HR, and benefits platform used by 400,000+ businesses: https://gusto.com/tim Seed's DS-01® Daily Synbiotic broad spectrum 24-strain probiotic + prebiotic: https://Seed.com/Tim David Protein Bars 28g of protein, 150 calories, and 0g of sugar: https://davidprotein.com/tim Coyote the card game, which I co-created with Exploding Kittens: https://coyotegame.com*For show notes and past guests on The Tim Ferriss Show, please visit tim.blog/podcast.For deals from sponsors of The Tim Ferriss Show, please visit tim.blog/podcast-sponsorsSign up for Tim's email newsletter (5-Bullet Friday) at tim.blog/friday.For transcripts of episodes, go to tim.blog/transcripts.Discover Tim's books: tim.blog/books.Follow Tim:Twitter: twitter.com/tferriss Instagram: instagram.com/timferrissYouTube: youtube.com/timferrissFacebook: facebook.com/timferriss LinkedIn: linkedin.com/in/timferrissSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
In this podcast, Series 4, Chapter 6, Dr. Barsuk interviews Dr. Martin Pusic, Associate Professor of Pediatrics and Emergency Medicine at Harvard Medical School and Senior Associate Faculty for Boston Children's Hospital and Scholar-in-Residence at the Brigham Education Institute, Brigham & Women's Hospital in Boston, MA. Dr. Pusic serves as Director of the American Board of Medical Specialties Research and Education Foundation. He is a medical doctor practicing as a pediatric emergency physician but also received a Doctor of Philosophy in Cognition and Learning. His research focuses on learning analytics and the role and impact of research, data, and informatics on medical education and learning. Drs. Barsuk and Pusic talk about research in medical education and initiatives at the ABMS.
In this intellectually engaging interview, Mark Underwood explores the frontiers of neuroscience and what modern brain research reveals about human consciousness, perception, and behavior. Drawing from scientific study and real-world research applications, Underwood breaks down complex neurological concepts into accessible insights, examining how the brain shapes thought, memory, learning, and awareness. This episode bridges science and curiosity, offering listeners a deeper understanding of the mind and the remarkable biological systems that define what it means to be human.Become a supporter of this podcast: https://www.spreaker.com/podcast/the-x-zone-radio-tv-show--1078348/support.Please note that all XZBN radio and/or television shows are Copyright © REL-MAR McConnell Meda Company, Niagara, Ontario, Canada – www.rel-mar.com. For more Episodes of this show and all shows produced, broadcasted and syndicated from REL-MAR McConell Media Company and The 'X' Zone Broadcast Network and the 'X' Zone TV Channell, visit www.xzbn.net. For programming, distribution, and syndication inquiries, email programming@xzbn.net.We are proud to announce the we have launched TWATNews.com, launched in August 2025.TWATNews.com is an independent online news platform dedicated to uncovering the truth about Donald Trump and his ongoing influence in politics, business, and society. Unlike mainstream outlets that often sanitize, soften, or ignore stories that challenge Trump and his allies, TWATNews digs deeper to deliver hard-hitting articles, investigative features, and sharp commentary that mainstream media won't touch.These are stories and articles that you will not read anywhere else.Our mission is simple: to expose corruption, lies, and authoritarian tendencies while giving voice to the perspectives and evidence that are often marginalized or buried by corporate-controlled media
From creating SWE-bench in a Princeton basement to shipping CodeClash, SWE-bench Multimodal, and SWE-bench Multilingual, John Yang has spent the last year and a half watching his benchmark become the de facto standard for evaluating AI coding agents—trusted by Cognition (Devin), OpenAI, Anthropic, and every major lab racing to solve software engineering at scale. We caught up with John live at NeurIPS 2025 to dig into the state of code evals heading into 2026: why SWE-bench went from ignored (October 2023) to the industry standard after Devin's launch (and how Walden emailed him two weeks before the big reveal), how the benchmark evolved from Django-heavy to nine languages across 40 repos (JavaScript, Rust, Java, C, Ruby), why unit tests as verification are limiting and long-running agent tournaments might be the future (CodeClash: agents maintain codebases, compete in arenas, and iterate over multiple rounds), the proliferation of SWE-bench variants (SWE-bench Pro, SWE-bench Live, SWE-Efficiency, AlgoTune, SciCode) and how benchmark authors are now justifying their splits with curation techniques instead of just "more repos," why Tau-bench's "impossible tasks" controversy is actually a feature not a bug (intentionally including impossible tasks flags cheating), the tension between long autonomy (5-hour runs) vs. interactivity (Cognition's emphasis on fast back-and-forth), how Terminal-bench unlocked creativity by letting PhD students and non-coders design environments beyond GitHub issues and PRs, the academic data problem (companies like Cognition and Cursor have rich user interaction data, academics need user simulators or compelling products like LMArena to get similar signal), and his vision for CodeClash as a testbed for human-AI collaboration—freeze model capability, vary the collaboration setup (solo agent, multi-agent, human+agent), and measure how interaction patterns change as models climb the ladder from code completion to full codebase reasoning. We discuss: John's path: Princeton → SWE-bench (October 2023) → Stanford PhD with Diyi Yang and the Iris Group, focusing on code evals, human-AI collaboration, and long-running agent benchmarks The SWE-bench origin story: released October 2023, mostly ignored until Cognition's Devin launch kicked off the arms race (Walden emailed John two weeks before: "we have a good number") SWE-bench Verified: the curated, high-quality split that became the standard for serious evals SWE-bench Multimodal and Multilingual: nine languages (JavaScript, Rust, Java, C, Ruby) across 40 repos, moving beyond the Django-heavy original distribution The SWE-bench Pro controversy: independent authors used the "SWE-bench" name without John's blessing, but he's okay with it ("congrats to them, it's a great benchmark") CodeClash: John's new benchmark for long-horizon development—agents maintain their own codebases, edit and improve them each round, then compete in arenas (programming games like Halite, economic tasks like GDP optimization) SWE-Efficiency (Jeffrey Maugh, John's high school classmate): optimize code for speed without changing behavior (parallelization, SIMD operations) AlgoTune, SciCode, Terminal-bench, Tau-bench, SecBench, SRE-bench: the Cambrian explosion of code evals, each diving into different domains (security, SRE, science, user simulation) The Tau-bench "impossible tasks" debate: some tasks are underspecified or impossible, but John thinks that's actually a feature (flags cheating if you score above 75%) Cognition's research focus: codebase understanding (retrieval++), helping humans understand their own codebases, and automatic context engineering for LLMs (research sub-agents) The vision: CodeClash as a testbed for human-AI collaboration—vary the setup (solo agent, multi-agent, human+agent), freeze model capability, and measure how interaction changes as models improve — John Yang SWE-bench: https://www.swebench.com X: https://x.com/jyangballin Chapters 00:00:00 Introduction: John Yang on SWE-bench and Code Evaluations 00:00:31 SWE-bench Origins and Devon's Impact on the Coding Agent Arms Race 00:01:09 SWE-bench Ecosystem: Verified, Pro, Multimodal, and Multilingual Variants 00:02:17 Moving Beyond Django: Diversifying Code Evaluation Repositories 00:03:08 Code Clash: Long-Horizon Development Through Programming Tournaments 00:04:41 From Halite to Economic Value: Designing Competitive Coding Arenas 00:06:04 Ofir's Lab: SWE-ficiency, AlgoTune, and SciCode for Scientific Computing 00:07:52 The Benchmark Landscape: TAU-bench, Terminal-bench, and User Simulation 00:09:20 The Impossible Task Debate: Refusals, Ambiguity, and Benchmark Integrity 00:12:32 The Future of Code Evals: Long Autonomy vs Human-AI Collaboration 00:14:37 Call to Action: User Interaction Data and Codebase Understanding Research
First off! I have started my second book! So stay tuned in 2026 And let's quickly recap 2025. Looking back is always so um interesting.Where is 2026 going..... let's hope it is all about the dogs! My TEDX Talk is live! Beyond Dog Training: The Movement Toward Sentience https://youtu.be/avUugazybwc Find all the episodes on Feedspot, where Dog Training DisrUPted is rated in the top 5 shows in the dog category in Canada: https://blog.feedspot.com/canadian_dog_podcasts/To become a certified Canine CBT Psychotherapist, and for courses on related topics, please visit the Institute of Canine Psychotherapy. www.instituteofcaninepsychotherapy.comBecome a Certified Canine Behaviorist and Dog TrainerMy Linktree with all my media, presentations, shows, articlesBillie Groom - UPWARD Dogology | Instagram, Facebook | LinktreeHere is the link to the recent article in Psychology Today Mag by Marc Bekoff on Canine CBTDog Training: Perception, Cognition, and Emotions | Psychology TodayBuy My Book! Winner of the 2019 American Best Book Fest Award (pets/narrative/non-fiction)The Art of Urban People With Adopted and Rescued Dogs Methodology: Rescued Dogs: The Misunderstood Breed: Groom, Billie: 9781525547287: Books - Amazon.ca
I denne og neste episode gir Lars og Pål en middels kort innføring i kognitiv belastningsteori, bedre kjent som cognitive load theory (CLT). Selv om teorien først ble formulert på 80-tallet, så er det først i de siste par årene at den begynt å få større oppmerksomhet i utdanningsfeltet. Vi snakker om de studiene som ledet John Sweller til å utforme teorien, om arbeidsminne og langtidsminne, ulike kilder til kunnskap, evolusjonær psykologi og hvordan Sweller inkluderte David Gearys distinksjon om biologisk primære og sekundære ferdigheter, generelle og domenespesifikke ferdigheter, kritisk tenking, indre og ytre belastning ved læring, og en rekke av de mest sentrale effekter som er kartlagt i CLT, og litt om kritikken som er blitt rettet mot teorien. I en tredje episode i denne lille serien, som vil komme ut litt etter disse to innføringsepisodene, vil vi også publisere et intervju som Lars gjorde med opphavsmannen til cognitive load theory, John Sweller. Anbefalinger nevnt i episoden: Willingham, D. T. (2023). Outsmart your brain: Why learning is hard and how you can make it easy. Gallery Books. Ashman, G. (2022). A little guide for teachers: Cognitive load theory. Corwin. Sweller, J. (2008). Instructional implications of David C. Geary's evolutionary educational psychology. Educational Psychologist, 43(4), 214–216. https://doi.org/10.1080/00461520802392208 Kirschner, P. A., Sweller, J., & Clark, R. E. (2006). Why minimal guidance during instruction does not work: An analysis of the failure of constructivist, discovery, problem-based, experiential, and inquiry-based teaching. Educational Psychologist, 41(2), 75–86. https://doi.org/10.1207/s15326985ep4102_1 Annet nevnt i episoden: Jorge Louis Borges, Mannen med den gode hukommelsen, fra samlingen Labyrinter Magnus Karlsens hukommelse blir testet: https://www.youtube.com/watch?v=eC1BAcOzHyY Bonawitz, E., Shafto, P., Gweon, H., Goodman, N. D., Spelke, E., & Schulz, L. (2011). The double-edged sword of pedagogy: Instruction limits spontaneous exploration and discovery. Cognition, 120(3), 322–330. https://doi.org/10.1016/j.cognition.2010.10.001 Morningside Academy: https://morningsideacademy.org/ Podkasten Sold a Story: https://features.apmreports.org/sold-a-story/ Tidligere Lars og Pål-episoder om relaterte tema: Episode 149 Den gamle skolen møter ny forskning, med Morten Brattbakk Episode 141 Hva vi har lært om læring så langt Episode 139 Stanislaw Pstrokonski from Education Bookcast Episode 135 Natalie Wexler on the role of knowledge in education Episode 127 Cro-Magnon på skolebenken ---------------------------- Logoen vår er laget av Sveinung Sudbø, se hans arbeider på originalkopi.com Musikken er av Arne Kjelsrud Mathisen, se facebooksiden Nygrenda Vev og Dur for mer info. ---------------------------- Takk for at du hører på. Ta kontakt med oss på larsogpaal@gmail.com Det finnes ingen bedre måte å få spredt podkasten vår til flere enn via dere lyttere, så takk om du deler eller forteller andre om oss. Både Lars og Pål skriver nå på hver sin blogg, med litt varierende regelmessighet. Du finner dem på disse nettsidene: https://paljabekk.com/ https://larssandaker.blogspot.com/ Alt godt, hilsen Lars og Pål
Butyrate, produced by gut bacteria when they ferment dietary fiber, acts as a signaling molecule in the gut-brain axis, influencing stress, pain tolerance, immunity, and brain health Through multiple mechanisms, including specific enzyme inhibition and NF-κB pathway regulation, butyrate reduces neuroinflammation and protects against neurodegenerative conditions like Alzheimer's and Parkinson's disease Butyrate influences key neurotransmitters including GABA, serotonin, and dopamine, while also increasing brain-derived neurotrophic factor (BDNF), which supports neuronal growth and cognitive function The vagus nerve serves as a communication highway between the gut and the brain, transmitting signals about butyrate levels that affect mood regulation, stress response, and immune function Optimizing gut health through dietary fiber and homemade fermented foods helps promote butyrate production and maintain a healthy gut-brain connection
Wat verraadt jouw lichaam, nog vóór je iets zegt? Een subtiele frons, een opgetrokken wenkbrauw of de manier waarop je een kamer binnenloopt: het laat vaak zien hoe jij je echt voelt. Psycholoog Guldan Turgut van de Vrije Universiteit Amsterdam is gespecialiseerd in het lezen van die onbewuste signalen. In deze aflevering legt ze uit hoe je lichaamstaal leert herkennen bij anderen én hoe je die kennis kunt inzetten om zelf sterker over te komen. Van een oprechte glimlach tot een zelfverzekerde houding en stemgebruik dat vertrouwen uitstraalt. Ideaal voor sollicitaties, dates en gesprekken waarin je indruk wilt maken. 00:00 Wat zijn micro-expressies? 01:47 Lichaamstaal tijdens een sollicitatie 02:29 Hoe herken je verschillende emoties? 04:20 Hoe herken je een echte glimlach of een neppe lach? 05:24 Hoe kun je gebruik maken van lichaamstaal? 07:15 Wat is een goede lichaamshouding? 09:20 Hoe kun je je stem het beste gebruiken? Bronnen: Wanneer lichaamstaal niet overeenkomt met woorden ► Jacob, H., Kreifelts, B., Brück, C., Nizielski, S., Schütz, A., & Wildgruber, D. (2013). Nonverbal signals speak up: Association between perceptual nonverbal dominance and emotional intelligence. Cognition and Emotion, 27(5), 783–799. https://doi.org/10.1080/02699931.2012.739999 Onderzoek met vechters in de ring ► Vaccaro, C. A., Schrock, D. P., & McCabe, J. M. (2011). Managing emotional manhood: Fighting and fostering fear in mixed martial arts. Social Psychology Quarterly, 74(4), 414–437. https://doi.org/10.1177/0190272511415554See omnystudio.com/listener for privacy information.
In this festive descent into methodological despair, Chris and Matt convene a secret cabal of elite psychology podcasters within the Decoding Cloister, operating under the distant yet reassuring gaze of Arch-Wizard Paul Bloom, whose role is largely ceremonial but nonetheless morally binding.Joining them are Dave Pizarro (Very Bad Wizards) and Michael Inzlicht (Two Psychologists Four Beers, emeritus), for what can only be described as an end-of-year audit of social psychology's moral character.What follows is a mixture of intense hubris, disciplinary self-loathing, and revolutionary insights, delivered via one of the most sadistic Christmas quizzes ever devised. The quiz format allows the episode to do what psychology does best: create the feeling of measurement while hovering dangerously close to intuition.Alongside the quiz, we engage in some meta-commentary and sensemaking reflections on audience capture and the state of psychology-themed podcasts in 2025. In other words, it's Christmas, so naturally everyone is discussing perverse incentives, damaged reputations, and the slow moral corrosion of institutions.So join us, won't you? For the first International Congress on Psychology-Themed Podcasting and Gurus…LinksMickey's SubstackMickey's Work and Play LabTwo Psychologists Four BeersVery Bad WizardsUhlmann, E. L., Pizarro, D. A., & Diermeier, D. (2015). A person-centered approach to moral judgment. Perspectives on Psychological Science, 10(1), 72-81.Ovsyannikova, D., de Mello, V. O., & Inzlicht, M. (2025). Third-party evaluators perceive AI as more compassionate than expert humans. Communications Psychology, 3(1), 4.ReferencesAlter, A. L., Oppenheimer, D. M., Epley, N., & Eyre, R. N. (2007). Overcoming intuition: Metacognitive difficulty activates analytic reasoning. Journal of Experimental Psychology: General, 136(4), 569–576.Aarts, H., & Dijksterhuis, A. (2003). The silence of the library: Environment, situational norm, and social behavior. Journal of Personality and Social Psychology, 84(1), 18–28.Zimbardo, P. G. (1973). On the ethics of intervention in human psychological research: With special reference to the Stanford Prison Experiment. Cognition, 2(2), 243–256.Resnick, B. (2018, June 13). The Stanford Prison Experiment was massively influential. We just learned it was a fraud. Vox.Festinger, L., Riecken, H. W., & Schachter, S. (1956). When prophecy fails. University of Minnesota Press.
Dr. Steven Franconeri explains the powerful insights and opportunities offered by a game he and his team created for having better disagreements about just about anything, but especially about the sort of topics that often lead to arguments, fights, and terrible holiday dinners.Kitted Executive AcademyPoint TakenThe Visual Thinking LabSteven FranconeriHow Minds ChangeDavid McRaney's TwitterDavid McRaney's BlueSkyYANSS TwitterShow NotesNewsletterPatreon Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
This Best of 2025 episode brings together the most impactful moments from the year - featuring highlights with Dr. William Li, Dr. Stacy Sims, Leslie Kenny, Darren Candow, Mark Sisson, and a solo episode of mine. Across metabolism, hormones, muscle, longevity and performance, these conversations reveal what actually works for midlife health. You'll hear why brown fat matters, how women should train and fuel as hormones shift, why muscle is essential for metabolic health, and how walking, sprinting and strength outperform chronic cardio. If you want a science-backed, no-nonsense snapshot of the ideas that shaped 2025 on the show, this episode connects the dots, and gives you clear, practical takeaways you can apply immediately. WHAT YOU'LL LEARN • How brown fat supports metabolism and fat loss • Why women need different training and fuelling strategies in midlife • The role of protein and creatine in muscle, energy and recovery • How autophagy supports immune and cellular health • Why walking and sprinting beat long-duration cardio for longevity Timestamps 00:00 Metabolism After 40: Fat, Food & the Real Science of Aging Well 17:53 How Women Should Fuel, Train & Recover for Hormonal Health and Longevity 30:53 Why Creatine Becomes Essential for Women's Strength, Brain & Daily Function 42:30 The Anti-Aging Pathway Most Women Haven't Heard About Yet (Spermidine) 48:39 Creatine, Cognition & Energy: A Smarter Approach to Women's Health 54:48 Walking as Medicine: Longevity, Strength & the Most Natural Form of Fitness VALUABLE RESOURCES A BIG thank you to our sponsors who make the show possible:• Ozlo Sleepbuds® – Fall asleep faster and stay asleep longer
You skip breakfast, push through lunch, and tell yourself you'll eat later, but instead, your head starts pounding. What if fasting isn't helping your focus, but quietly stressing your brain into a migraine attack?In this episode of Migraine Heroes Podcast, host Diane Ducarme explores the paradox of fasting — why it can be both a healing tool and a hidden stressor for migraine-prone brains. With insights from neuroscience and Eastern medicine, you'll learn how to find your balance between cleansing and collapse.You'll discover:
No Priors: Artificial Intelligence | Machine Learning | Technology | Startups
Pundits are screaming about the so-called “AI bubble.” But historically slow-to-adopt industries like medicine and law are actually embracing AI at an unprecedented speed. Sarah Guo and Elad Gil look ahead to 2026, breaking down the major trends that will define the next era of AI technologies. They explore the future of AI foundational models, predicting breakthroughs in solving complex scientific problems. They share competing views on the timeline for robotics and self-driving cars, debating whether startups have a chance for survival or if incumbents will dominate. Elad and Sarah also discuss the return of tech IPOs and M&As, forecast a new wave of AI consumer agent software, and explore why consumer product innovation has been slower than expected. Finally, the two offer bold non-AI predictions for the new year, including the acceleration of defense tech startups and the second-order underrated impacts of GLP-1 drugs on biohacking. Plus, stick around to hear predictions on what's next for AI in 2026 from some of tech's biggest names and industry leaders. We hear from Jensen Huang (Founder/CEO NVIDIA), Arvind Jain (Founder/CEO, Glean), Winston Weinberg (Founder/CEO, Harvey), Scott Wu (Founder/CEO, Cognition), Raiza Martin (Founder/CEO Huxe), Zach Ziegler (Founder/CTO, Open Evidence), Aaron Levie (Founder/CEO, Box), Misha Laskin (Founder/CEO, ReflectionAI), Noam Brown (Research Scientist, OpenAI), Joshua Meier (Founder/CEO Chai Discovery), Bryan Johnson (Living Man, Don't Die), Sholto Douglas (Member of the Technical Staff, Anthropic), Ben & Asher Spector (Stanford PhDs) and Dylan Patel (Founder/CEO SemiAnalysis). Sign up for new podcasts every week. Email feedback to show@no-priors.com Follow us on Twitter: @NoPriorsPod | @Saranormous | @EladGil Chapters: 00:00 – Introduction 02:43 – AI Predictions for 2026 04:40 – Adoption of AI in Professional Fields 07:17 – Robotics and Self-Driving Cars 08:25 – Robotics: Incumbents vs. Startups 13:59 – Future of IPOs and M&A in AI 16:42 – Challenges in Consumer AI Innovation 21:08 – Funding of Neo Labs, RL Research 26:28 – Predictions for 2026 Beyond AI 26:44 – The Future of Defense and Technology 28:23 – Biohacking and Peptide Therapies 30:37 – 2026 Prediction from AI Industry Leaders 40:46 – Conclusion
On this episode of the Scouting For Growth podcast, Sabine VdL talks to Marinela Profi, Global Market Strategy Lead for AI, GenAI and Agentic AI at SAS, about the rise of agentic AI and how we will move from hype to real, reliable AI. In today's episode, we'll discuss: Why LLMs alone don't solve business problems – and what does, how governance is becoming the new frontier of AI trust, and what leaders should expect by 2026, as enterprises shift from experiments to autonomous, explainable intelligence. KEY TAKEAWAYS A generative AI chatbot is really good and answering questions, generating text, or summarising content. But, it typically stops when it comes to conversation. On the other hand, an AI agent goes beyond that, it can take action, it has goals, memory, reasoning capabilities and can orchestrate multi-set workflows using a combination of not just large-language models but also rules, data and analytics. Generative AI talks, and agentic AI does. The 5-step lifecycle of an agent is a framework I put together to help me and my customers understand what an agent actually does step-by-step in practice. 1. Perception 2. Cognition 3. Decisioning 4. Action, and 5. Learning. Governance boards in 2026 will act more like digital oversight committees, they will ensure that agents aren't just smart, but they are safe, explainable and accountable. BEST MOMENTS ‘Post action the agent learns from feedback from a human operative. It's important to monitor the learning loops, you cannot allow the agent to “self-update” in ways that are uncontrolled.' ‘How autonomous should an agent be? 90% of the time it depends on the risk and impact of the task.' ‘Autonomy without accountability is a risk multiplier.' ‘Governance doesn't stop at deployment, performance must be continuously monitored.' ABOUT THE GUEST Marinela Profi helps organizations move from AI hype to trusted impact. As Global Market Strategy Lead for AI, GenAI and Agentic AI at SAS, she works with enterprises in financial services, healthcare, and government to build AI systems that don't just act fast—but act responsibly. With an MBA and a Master's in Statistics and AI, Marinela bridges two worlds: translating complex data science into clear business strategy. Her work focuses on how agentic AI—intelligent systems that perceive, reason, and act autonomously—can deliver governed, explainable decisions instead of black-box predictions. A frequent keynote speaker at international AI and analytics events, she shares insights on the evolution from generative to agentic AI and the new frontier of AI governance, trust, and human-AI collaboration. Marinela is also an Advisory Board Member for Wake Technical Community College's Data Science Program, helping shape future-ready curricula that connect classroom learning with real-world AI innovation. ABOUT THE HOST Sabine is a corporate strategist turned entrepreneur. She is the CEO and Managing Partner of Alchemy Crew a venture lab that accelerates the curation, validation, & commercialization of new tech business models. Sabine is renowned within the insurance sector for building some of the most renowned tech startup accelerators around the world working with over 30 corporate insurers, accelerated over 100 startup ventures. Sabine is the co-editor of the bestseller The INSURTECH Book, a top 50 Women in Tech, a FinTech and InsurTech Influencer, an investor & multi-award winner. Twitter LinkedIn Instagram Facebook TikTok Email Website This Podcast has been brought to you by Disruptive Media. https://disruptivemedia.co.uk/
A new book about puzzles claims 36 million Americans solve crosswords once a week or more, and nearly 23 million solve them daily. Natan Last, a researcher, policy advisor, writer, and crossword constructor in New York City, joins us to discuss his book, Across the Universe: The Past, Present, and Future of the Crossword Puzzle.
Send us a textStrap in, kids. This episode is the equivalent of a Tasty Gains creatine gummy to the dome—sweet, punchy, and packed with fire. The crew goes full send on everything from the absurd pipeline reorg memos to SEER spouses who think a YouTube comment is a call to arms. Peaches drops savage truths about military hierarchy, pipeline chaos, and why instructors are the ones always eating the crap sandwich. Also: war stories, karaoke bangers, and a weather guy who thinks he's a JTAC. If you're mad? Good. That means you're listening.
In the final episode of our five-part series on primary progressive aphasia (PPA), Dr. Rogan Magee discusses bedside testing for PPA. Show citations: Show citations: Grossman M, Seeley WW, Boxer AL, et al. Frontotemporal lobar degeneration. Nat Rev Dis Primers. 2023;9(1):40. Published 2023 Aug 10. doi:10.1038/s41572-023-00447-0 Gorno-Tempini ML, Hillis AE, Weintraub S, et al. Classification of primary progressive aphasia and its variants. Neurology. 2011;76(11):1006-1014. doi:10.1212/WNL.0b013e31821103e6 Santos-Santos MA, Rabinovici GD, Iaccarino L, et al. Rates of Amyloid Imaging Positivity in Patients With Primary Progressive Aphasia. JAMA Neurol. 2018;75(3):342-352. doi:10.1001/jamaneurol.2017.4309 Mandelli ML, Lorca-Puls DL, Lukic S, et al. Network anatomy in logopenic variant of primary progressive aphasia. Hum Brain Mapp. 2023;44(11):4390-4406. doi:10.1002/hbm.26388 Putcha D, Erkkinen M, Daffner KR. Functional Neurocircuitry of Cognition and Cognitive Syndromes. In: Silbersweig DA, Safar LT, Daffner KR. eds. Neuropsychiatry and behavioral neurology: principles and practice. McGraw Hill; 2021. Accessed November 6, 2025. https://neurology.mhmedical.com/content.aspx?bookid=3007§ionid=253215676 Montembeault M, Brambati SM, Gorno-Tempini ML, Migliaccio R. Clinical, Anatomical, and Pathological Features in the Three Variants of Primary Progressive Aphasia: A Review. Front Neurol. 2018;9:692. Published 2018 Aug 21. doi:10.3389/fneur.2018.00692 Clark DG. Frontotemporal Dementia. Continuum (Minneap Minn). 2024;30(6):1642-1672. doi:10.1212/CON.0000000000001506
******Support the channel******Patreon: https://www.patreon.com/thedissenterPayPal: paypal.me/thedissenterPayPal Subscription 1 Dollar: https://tinyurl.com/yb3acuuyPayPal Subscription 3 Dollars: https://tinyurl.com/ybn6bg9lPayPal Subscription 5 Dollars: https://tinyurl.com/ycmr9gpzPayPal Subscription 10 Dollars: https://tinyurl.com/y9r3fc9mPayPal Subscription 20 Dollars: https://tinyurl.com/y95uvkao ******Follow me on******Website: https://www.thedissenter.net/The Dissenter Goodreads list: https://shorturl.at/7BMoBFacebook: https://www.facebook.com/thedissenteryt/Twitter: https://x.com/TheDissenterYT This show is sponsored by Enlites, Learning & Development done differently. Check the website here: http://enlites.com/ Dr. Giovanni Rolla is Professor of Philosophy at Federal University of Bahia (UFBA), Brazil. His research is about enactivism, ecological psychology and radically embodied cognition in general (sometimes he deals with traditional epistemology as well, especially know-how, normativity and rationality). He is also a founding member of the Enactive Cognition and Narrative Practices research group (University of Wollongong), and a founding member of the Cognition, Language, Enaction and Affectivity research group. In this episode, we start by talking about enactivism, and how it differs from cognitivism and other traditional approaches in cognitive science. We talk about combining enactivism, ecological psychology and embodied cognition. We discuss what information is in cognitive science, what know-how is, and the enactivist conception of “bringing forth a world”. We talk about the relationship between enactivism and evolutionary dynamics, and evolution as natural drift. We discuss whether pre-linguistic infants have representational abilities. Finally, we talk about Radically Enactive Cognition, and how rationality is approached from this perspective.--A HUGE THANK YOU TO MY PATRONS/SUPPORTERS: PER HELGE LARSEN, JERRY MULLER, BERNARDO SEIXAS, ADAM KESSEL, MATTHEW WHITINGBIRD, ARNAUD WOLFF, TIM HOLLOSY, HENRIK AHLENIUS, ROBERT WINDHAGER, RUI INACIO, ZOOP, MARCO NEVES, COLIN HOLBROOK, PHIL KAVANAGH, SAMUEL ANDREEFF, FRANCIS FORDE, TIAGO NUNES, FERGAL CUSSEN, HAL HERZOG, NUNO MACHADO, JONATHAN LEIBRANT, JOÃO LINHARES, STANTON T, SAMUEL CORREA, ERIK HAINES, MARK SMITH, JOÃO EIRA, TOM HUMMEL, SARDUS FRANCE, DAVID SLOAN WILSON, YACILA DEZA-ARAUJO, ROMAIN ROCH, YANICK PUNTER, CHARLOTTE BLEASE, NICOLE BARBARO, ADAM HUNT, PAWEL OSTASZEWSKI, NELLEKE BAK, GUY MADISON, GARY G HELLMANN, SAIMA AFZAL, ADRIAN JAEGGI, PAULO TOLENTINO, JOÃO BARBOSA, JULIAN PRICE, HEDIN BRØNNER, FRANCA BORTOLOTTI, GABRIEL PONS CORTÈS, URSULA LITZCKE, SCOTT, ZACHARY FISH, TIM DUFFY, SUNNY SMITH, JON WISMAN, WILLIAM BUCKNER, LUKE GLOWACKI, GEORGIOS THEOPHANOUS, CHRIS WILLIAMSON, PETER WOLOSZYN, DAVID WILLIAMS, DIOGO COSTA, ALEX CHAU, CORALIE CHEVALLIER, BANGALORE ATHEISTS, LARRY D. LEE JR., OLD HERRINGBONE, MICHAEL BAILEY, DAN SPERBER, ROBERT GRESSIS, JEFF MCMAHAN, JAKE ZUEHL, MARK CAMPBELL, TOMAS DAUBNER, LUKE NISSEN, KIMBERLY JOHNSON, JESSICA NOWICKI, LINDA BRANDIN, VALENTIN STEINMANN, ALEXANDER HUBBARD, BR, JONAS HERTNER, URSULA GOODENOUGH, DAVID PINSOF, SEAN NELSON, MIKE LAVIGNE, JOS KNECHT, LUCY, MANVIR SINGH, PETRA WEIMANN, CAROLA FEEST, MAURO JÚNIOR, 航 豊川, TONY BARRETT, NIKOLAI VISHNEVSKY, STEVEN GANGESTAD, TED FARRIS, HUGO B., JAMES, JORDAN MANSFIELD, CHARLOTTE ALLEN, PETER STOYKO, DAVID TONNER, LEE BECK, PATRICK DALTON-HOLMES, NICK KRASNEY, RACHEL ZAK, AND DENNIS XAVIER!A SPECIAL THANKS TO MY PRODUCERS, YZAR WEHBE, JIM FRANK, ŁUKASZ STAFINIAK, TOM VANEGDOM, BERNARD HUGUENEY, CURTIS DIXON, BENEDIKT MUELLER, THOMAS TRUMBLE, KATHRINE AND PATRICK TOBIN, JONCARLO MONTENEGRO, NICK GOLDEN, CHRISTINE GLASS, IGOR NIKIFOROVSKI, PER KRAULIS, AND JOSHUA WOOD!AND TO MY EXECUTIVE PRODUCERS, MATTHEW LAVENDER, SERGIU CODREANU, ROSEY, AND GREGORY HASTINGS!
In this high-impact solo episode, Darin strips away the noise, hacks, and hype to deliver a clear, no-BS roadmap for transforming your body, brain, energy, and direction in life. This is a straight-talk breakdown of the 5 foundational habits that matter most — the habits backed by science, ancient wisdom, and Darin's decades-long experience living this work every day. Expect practical steps, micro-experiments, timing rules, and the mindset needed to reclaim sovereignty in a world full of distraction. If you're ready to build a stronger, clearer, more powerful version of yourself… this is the episode. What You'll Learn 00:00 – Welcome to SuperLife How this podcast helps you build sovereignty through real habits, real truth, and real practices. 03:07 – Why this episode is different Darin lays out the mission: habits, hacks, hard truths — without dogma or fluff. 03:44 – The 5 foundational moves that change your biology A preview of the metabolic, physical, mental, and behavioral levers that create huge shifts. 1. METABOLIC EDGE — Eat Like You're Building a Future 04:03 – Terrain theory + why your food timing matters How altering the internal environment of your cells changes everything. 05:02 – The two levers that unlock metabolic health Time-restricted eating + plant-forward whole foods. 05:23 – Compressing your eating window Why 8–10 hours is ideal, how it improves glucose, insulin, weight, and inflammation. 06:18 – Practical weekly ramp-up Week 1: 12 hours. Week 2: 8–10 hours. Simple, sustainable, achievable. 07:10 – Darin's personal eating window 10 a.m. to 6 p.m. — and why eating earlier aligns with digestive fire. 2. MOVEMENT THAT MATTERS — Strength Is Survival 11:04 – Why strength training is non-negotiable Muscle protects metabolism, bone density, insulin sensitivity, and longevity. 11:51 – What the evidence says Huge cohort studies show strength training reduces all-cause mortality. 12:23 – The perfect weekly formula 3x/week compound lifts + daily movement + micro-bursts every hour. 13:06 – Real-life practicality Darin's routine of walking, sprinting dogs, mountain biking, and breaking up the day with movement. 3. SLEEP — The Ultimate Biological Reset 16:26 – The truth everyone ignores You cannot out-supplement or out-biohack poor sleep. 16:40 – The real impact of chronic sleep loss Cognition, memory, hormones, emotional regulation — all decline. 17:37 – The universal rule: consistent timing Same bedtime ± 30 minutes, every night. 17:52 – 60-minute wind-down protocol Screens off, light down, nervous system softening. 18:32 – Using sauna as a down-regulation tool Infrared benefits + why Darin does it twice a day in winter. 4. MINDSET & CONSCIOUSNESS — Your Attention Is Your Power 20:00 – Why optimization fails without attention training You can master food, workouts, and sleep — but scattered attention destroys progress. 20:48 – Darin's morning protocol Water → elixir → infrared pad → meditation → visualization → journaling. Every day. Everywhere. 21:01 – Meta-analysis proof Meditation reduces anxiety, depression, stress — and rewires your brain. 21:23 – The perfect 10-minute breathwork formula 5–5–5–5 or 4–4–4–4 cycles for nervous system reset. 21:56 – Journaling as medicine Stream-of-consciousness to activate clarity and emotional release. 5. WEALTH — Treat Your Time Like Capital 22:36 – Redefining wealth It's not money — it's your magnetism, output, relationships, and purpose. 23:16 – The compounding effect of tiny decisions Time batching, micro-actions, and protecting your attention from the social media attention economy. 24:02 – Mini productivity framework 90 seconds → 3 important calls. Every Friday → 1 paragraph on what scaled this week. 25:14 – Darin's post-meditation rule No scrolling — replace with proactive actions: reading, outreach, Patreon replies. FINAL TAKEAWAYS 26:02 – The master checklist: • Time-restricted eating • Plant-focused meals • Resistance training • Daily meditation • Consistent sleep • Sauna recovery • Treating time like capital 26:11 – The real danger Chasing hacks before mastering fundamentals leads to burnout, confusion, and stress. 27:58 – Your power is in the basics These are simple, accessible, and life-changing. 28:04 – Closing message "Have your best Super Life Day ever." Thank You to Our Sponsors Our Place: Toxic-free, durable cookware that supports healthy cooking. Go to their website at fromourplace.com/darin and get 35% off sitewide in their largest sale of the year. Manna Vitality: Go to mannavitality.com/ and use code DARIN12 for 12% off your order. Join the SuperLife Community Get Darin's deeper wellness breakdowns — beyond social media restrictions: Weekly voice notes Ingredient deep dives Wellness challenges Energy + consciousness tools Community accountability Extended episodes Join for $7.49/month → https://patreon.com/darinolien Find More from Darin Olien: Instagram: @darinolien Podcast: SuperLife Podcast Website: superlife.com Book: Fatal Conveniences Key Takeaway "Your biology changes when your decisions change. Nail your sleep, nail your strength, honor your attention, and treat your time like capital — and you will build a Super Life from the ground up." Bibliography Time-restricted eating (human RCTs / reviews) — Wilkinson et al., 10-hour TRE reduced weight and improved cardiometabolic markers (2019). PMC Intermittent fasting / metabolic health review — comprehensive reviews showing metabolic switching benefits. PMC+1 Plant-forward/vegetarian diets & cardiometabolic outcomes — BMJ/Nutrition reviews and JAMA network evidence showing improved CVD risk markers and metabolic benefits. BMJ Nutrition+1 Sleep and cognition / brain health — Nature/Harvard coverage & meta-analyses: short sleep impairs cognition and links to amyloid processes. Nature+1 Resistance training & mortality / physical function — systematic and cohort evidence that muscle-strengthening activity lowers risk and preserves function. British Journal of Sports Medicine+1 Mindfulness & mental health meta-analysis — Goyal et al. 2014 and subsequent meta-analyses showing reductions in anxiety/stress. PubMed+1 Sauna bathing and cardiovascular outcomes — JAMA Internal Medicine / Mayo Clinic Proceedings reviews on sauna and lower CVD risk signals.
In this episode of Science of Reading: The Podcast, Susan Lambert is joined by Affiliated Scholar at the Stern Center for Language and Learning, Melissa Farrall, Ph.D., to discuss understanding assessment. Melissa explains why it's beneficial for every educator to understand the fundamentals of assessment, especially comprehension assessment. Together, Melissa and Susan discuss the relationship between reading comprehension and language comprehension, why reading comprehension can be challenging to assess, and how, in a perfect world, educators would be trained both in the Science of Reading and assessment.Show notes:Submit your questions on comprehension!Access free, high-quality resources at our brand new, companion professional learning page.Connect with Melissa Farrall on LinkedIn.Learn more about Chall's Stages of Reading Development.Read The Academic Achievement Challenge: What Really Works in the ClassroomListen to Season 2 of Amplify's Beyond My Years podcast.Join our community Facebook group.Connect with Susan Lambert. Quotes:"My view of reading comprehension is that it is thinking guided by print." —Melissa Farrall, Ph.D."If we supplement our evaluation with measures of listening comprehension, we can then get a sense of an individual's ability to make meaning." —Melissa Farrall, Ph.D."In a perfect world, we would have not just evaluators, but educators who are trained both in the Science of Reading and in assessment so that we can all sit at the same table and participate." —Melissa Farrall, Ph.D.Episode Timestamps:00:00 Introduction: Exploring comprehension assessment, with Melissa Farrall07:00 The legacy of Jean Chall's research on the developmental stages of reading10:00 "Reading Assessment: Linking Language, Literacy, and Cognition"17:00 Comprehension is thinking guided by print21:00 Different ways of assessing reading comprehension27:00 Kintsch's construction-integration model30:00 Word recognition33:00 Reading comprehension is not easily quantified38:00 How background knowledge affect the meaning-making process41:00 The two modalities of language comprehension45:00 How today's educators might think differently about comprehension instruction48:00 Closing thoughts*Timestamps are approximate, rounded to nearest minute
In the final episode of our five-part series on primary progressive aphasia (PPA), Dr. Rogan Magee discusses bedside testing for PPA. Show citations: Grossman M, Seeley WW, Boxer AL, et al. Frontotemporal lobar degeneration. Nat Rev Dis Primers. 2023;9(1):40. Published 2023 Aug 10. doi:10.1038/s41572-023-00447-0 Gorno-Tempini ML, Hillis AE, Weintraub S, et al. Classification of primary progressive aphasia and its variants. Neurology. 2011;76(11):1006-1014. doi:10.1212/WNL.0b013e31821103e6 Santos-Santos MA, Rabinovici GD, Iaccarino L, et al. Rates of Amyloid Imaging Positivity in Patients With Primary Progressive Aphasia. JAMA Neurol. 2018;75(3):342-352. doi:10.1001/jamaneurol.2017.4309 Mandelli ML, Lorca-Puls DL, Lukic S, et al. Network anatomy in logopenic variant of primary progressive aphasia. Hum Brain Mapp. 2023;44(11):4390-4406. doi:10.1002/hbm.26388 Putcha D, Erkkinen M, Daffner KR. Functional Neurocircuitry of Cognition and Cognitive Syndromes. In: Silbersweig DA, Safar LT, Daffner KR. eds. Neuropsychiatry and behavioral neurology: principles and practice. McGraw Hill; 2021. Accessed November 6, 2025. https://neurology.mhmedical.com/content.aspx?bookid=3007§ionid=253215676 Montembeault M, Brambati SM, Gorno-Tempini ML, Migliaccio R. Clinical, Anatomical, and Pathological Features in the Three Variants of Primary Progressive Aphasia: A Review. Front Neurol. 2018;9:692. Published 2018 Aug 21. doi:10.3389/fneur.2018.00692 Clark DG. Frontotemporal Dementia. Continuum (Minneap Minn). 2024;30(6):1642-1672. doi:10.1212/CON.0000000000001506
Drs. Audrey Thurm and Latha Soorya join us to discuss key findings from the NIH-funded Natural History Study in Phelan-McDermid syndrome, including intellectual disability profiles, daily living skill growth, regression, and how caregiver input drives research. Learn how these discoveries are guiding clinical trials, behavioral therapy, and everyday care—and why your family's participation makes all the difference.
In the fourth installment of our series on primary progressive aphasia (PPA), Dr. Rogan Magee discusses semantic variant PPA. Show citations: Grossman M, Seeley WW, Boxer AL, et al. Frontotemporal lobar degeneration. Nat Rev Dis Primers. 2023;9(1):40. Published 2023 Aug 10. doi:10.1038/s41572-023-00447-0 Gorno-Tempini ML, Hillis AE, Weintraub S, et al. Classification of primary progressive aphasia and its variants. Neurology. 2011;76(11):1006-1014. doi:10.1212/WNL.0b013e31821103e6 Santos-Santos MA, Rabinovici GD, Iaccarino L, et al. Rates of Amyloid Imaging Positivity in Patients With Primary Progressive Aphasia. JAMA Neurol. 2018;75(3):342-352. doi:10.1001/jamaneurol.2017.4309 Mandelli ML, Lorca-Puls DL, Lukic S, et al. Network anatomy in logopenic variant of primary progressive aphasia. Hum Brain Mapp. 2023;44(11):4390-4406. doi:10.1002/hbm.26388 Putcha D, Erkkinen M, Daffner KR. Functional Neurocircuitry of Cognition and Cognitive Syndromes. In: Silbersweig DA, Safar LT, Daffner KR. eds. Neuropsychiatry and behavioral neurology: principles and practice. McGraw Hill; 2021. Accessed November 6, 2025. https://neurology.mhmedical.com/content.aspx?bookid=3007§ionid=253215676 Montembeault M, Brambati SM, Gorno-Tempini ML, Migliaccio R. Clinical, Anatomical, and Pathological Features in the Three Variants of Primary Progressive Aphasia: A Review. Front Neurol. 2018;9:692. Published 2018 Aug 21. doi:10.3389/fneur.2018.00692 Clark DG. Frontotemporal Dementia. Continuum (Minneap Minn). 2024;30(6):1642-1672. doi:10.1212/CON.0000000000001506
Struggling with brain fog? The answer might be in your gut. In this episode, I'll explore the root causes of brain fog and reveal how gut health plays a crucial role in mental clarity. Discover the key signs to watch for, evidence-based supplements that actually work, and actionable treatment strategies to reclaim your focus and cognitive function. What you'll learn: ⚠️ Common signs and underlying causes of brain fog beyond stress and lack of sleep
In the third installment of our series on primary progressive aphasia (PPA), Dr. Rogan Magee discusses nonfluent/agrammatic PPA. Show citations: Grossman M, Seeley WW, Boxer AL, et al. Frontotemporal lobar degeneration. Nat Rev Dis Primers. 2023;9(1):40. Published 2023 Aug 10. doi:10.1038/s41572-023-00447-0 Gorno-Tempini ML, Hillis AE, Weintraub S, et al. Classification of primary progressive aphasia and its variants. Neurology. 2011;76(11):1006-1014. doi:10.1212/WNL.0b013e31821103e6 Santos-Santos MA, Rabinovici GD, Iaccarino L, et al. Rates of Amyloid Imaging Positivity in Patients With Primary Progressive Aphasia. JAMA Neurol. 2018;75(3):342-352. doi:10.1001/jamaneurol.2017.4309 Mandelli ML, Lorca-Puls DL, Lukic S, et al. Network anatomy in logopenic variant of primary progressive aphasia. Hum Brain Mapp. 2023;44(11):4390-4406. doi:10.1002/hbm.26388 Putcha D, Erkkinen M, Daffner KR. Functional Neurocircuitry of Cognition and Cognitive Syndromes. In: Silbersweig DA, Safar LT, Daffner KR. eds. Neuropsychiatry and behavioral neurology: principles and practice. McGraw Hill; 2021. Accessed November 6, 2025. https://neurology.mhmedical.com/content.aspx?bookid=3007§ionid=253215676 Montembeault M, Brambati SM, Gorno-Tempini ML, Migliaccio R. Clinical, Anatomical, and Pathological Features in the Three Variants of Primary Progressive Aphasia: A Review. Front Neurol. 2018;9:692. Published 2018 Aug 21. doi:10.3389/fneur.2018.00692 Clark DG. Frontotemporal Dementia. Continuum (Minneap Minn). 2024;30(6):1642-1672. doi:10.1212/CON.0000000000001506
durée : 00:05:13 - Avec sciences - par : Alexandra Delbot - Les mots peuvent-ils faire frissonner le cerveau ? Une nouvelle étude montre que lire des mots désagréables comme "je grelotte" ou "je brûle" active l'insula, région qui traite habituellement ces sensations pour de vrai. Le cerveau réagit à la lecture comme s'il vivait véritablement l'expérience. - invités : Marcela Perrone-Bertolotti Maîtresse de conférence à l'Université Grenoble Alpes et chercheuse au laboratoire de psychologie et neurocognition
Today, I am delighted to be joined by a friend and colleague, Mike Mutzel. Mike has a master's in Clinical Nutrition from the University of Bridgeport. He is a graduate of the IFM, applies functional medicine in clinical practice, and is a consultant lecturer who teaches leading-edge science in a concise format for progressive clinicians to prevent chronic diseases. In our discussion, Mike and I unpack the benefits of creatine monohydrate, highlighting the importance of ensuring the products we use are free of impurities. We explain how creatine monohydrate gets created, answer many listener questions, and describe current research specific to creatine monohydrate, discussing ways to support bone health, navigate dosing, and how to troubleshoot. This conversation with Mike Mutzel is truly invaluable, and I look forward to having him back on the podcast to dive a little deeper into the science. IN THIS EPISODE, YOU WILL LEARN: How creatine supports energy production across muscles, the brain, and other organ systems Why vegetarians and vegans should take creatine What to consider when choosing high-quality creatine supplements Dosing strategies based on diet, exercise, sleep, and individual needs How taking creatine with electrolytes while exercising can improve absorption Benefits of supplementing with amino acids alongside creatine for illness, recovery, or when protein intake is low Adjusting your creatine dosage for sleep, travel, or exercise demands How creatine supports bone and muscle health The value of creatine for the eyes and ears Connect with Cynthia Thurlow Follow on X, Instagram & LinkedIn Check out Cynthia's website Submit your questions to support@cynthiathurlow.com Connect with Mike Mutzel On his website YouTube Instagram High Intensity Health Podcast Creatine Research: Creatine in Women's Health: Bridging the Gap From Menstruation Through Pregnancy to Menopause Effects of Creatine and Resistance Training on Bone Health in Postmenopausal Women Creatine Supplementation (3 g/d) and Bone Health in Older Women: A 2-Year, Randomized, Placebo-Controlled Trial Creatine Supplementation in Depression: A Review of Mechanisms, Efficacy, Clinical Outcomes, and Future Directions The Effects of 8-Week Creatine Hydrochloride and Creatine Ethyl Ester Supplementation on Cognition, Clinical Outcomes, and Brain Creatine Levels in Perimenopausal and Menopausal Women (CONCRET-MENOPA): A Randomized Controlled Trial
In this solo episode, Darin explores a radical idea backed by ancient wisdom and modern neuroscience: that awe — a single embodied moment of wonder — may be the fastest biological doorway to expanding consciousness. Drawing on cutting-edge research, timeless spiritual traditions, and personal stories, Darin reveals how awe reduces inflammation, rewires the brain, quiets the ego, boosts vagal tone, expands time perception, and reconnects us to meaning in a world drowning in distraction. What You'll Learn in This Episode 00:00 — Welcome to SuperLife: igniting sovereignty, possibility, and human potential 00:32 — Sponsor: Therasage — the most nutrient-dense food on Earth 01:51 — Today's topic: Awe as a biological shortcut to consciousness 02:00 — The definition of awe: when the world becomes bigger than your understanding 02:17 — Awe literally changes the brain — research from Dacher Keltner 02:23 — What if the fastest way to expand consciousness isn't meditation or psychedelics… but a single moment of awe? 02:34 — "Embodied awe" as a key humans have overlooked 02:41 — Science is catching up — the physiological effects of awe 02:47 — Awe reduces inflammation, rewires neural pathways, and increases connection 02:55 — Modern life has cut us off from awe — but nature left a back door 03:02 — Awe as a temporary collapse of ego → widening of consciousness 03:12 — What awe feels like: chest expansion, mind quieting, heart opening 03:22 — Awe is triggered by vastness — moments that shift your framework 03:31 — Awe motivates us to transcend self-interest and connect to something bigger 03:47 — Examples of awe: star-filled sky, ancient trees, rivers carving canyons 04:01 — 90% of humans can't see the stars anymore — light pollution crisis 04:23 — Awe in music, nature, micro-patterns, the beauty of small things 05:00 — Awe in ancient traditions: Darshan, Greek thauma, Biblical reverence 05:12 — Darin's hawk story — the personal power of unexpected awe 06:03 — The science of awe: IL-6, immune markers, inflammation reduction 06:28 — Awe quiets the Default Mode Network — the home of the ego 06:43 — Less rumination → more presence, clarity, and connection 07:06 — Awe expands time perception — Stanford research on "time abundance" 07:32 — Awe increases generosity, altruism, pro-social behavior 08:04 — Awe boosts vagal tone: calm, resilience, emotional regulation 08:22 — Why we are STARVING for awe — screens, indoor living, disconnection 08:57 — Sponsor: Caldera Lab 11:33 — "We've traded the vastness of the universe for tiny screens." 11:40 — How to reclaim awe: look at the sky, clouds, moon, trees 11:53 — Let your eyes adjust to nature again 12:03 — Astronomical awe puts your problems in perspective 12:14 — Awe as emotional first-aid: go outside, find the horizon 12:30 — Limit phone time — reduce micro-dopamine addiction 13:02 — Micro-awe: the patterns in a leaf, the sunlight through branches 13:12 — Nature is always available — if you choose it 13:16 — Awe as the ultimate nervous-system reset 13:27 — Circadian alignment: dim lights, follow nature 13:56 — Humility = freedom — awe repositions your place in the universe 14:19 — Awe is biological, spiritual, emotional nourishment 14:27 — Awe is the ultimate bio-hack 14:35 — Awe reduces inflammation, expands time, deepens empathy 14:46 — "Awe is the gateway to the self-transcendent." 14:55 — If you want more meaning, vitality, and connection — start with awe 15:02 — Awe reduces stress, boosts empathy, reconnects you to your soul 15:18 — Awe reconnects you to what actually matters 15:30 — Final message: Have yourself the best SuperLife day ever Thank You to Our Sponsors: Therasage: Go to www.therasage.com and use code DARIN at checkout for 15% off Caldera Lab: Experience the clinically proven benefits of Caldera Lab's clean skincare regimen and enjoy 20% off your order by visiting calderalab.com/darin and using code DARIN at checkout. Join the SuperLife Community Get Darin's deeper wellness breakdowns — beyond social media restrictions: Weekly voice notes Ingredient deep dives Wellness challenges Energy + consciousness tools Community accountability Extended episodes Join for $7.49/month → https://patreon.com/darinolien Find More from Darin Olien: Instagram: @darinolien Podcast: SuperLife Podcast Website: superlife.com Book: Fatal Conveniences Key Takeaway "Awe isn't entertainment — it's medicine. It's the biological, emotional, and spiritual nourishment your body has been starving for. Reclaim awe, and you reclaim your soul." Bibliography & Research Sources Bai, Y., Ocampo, J., Jin, G., Chen, S., Benet-Martínez, V., Monroy, M., Anderson, C., & Keltner, D. (2021). Awe, daily stress, and well-being. Emotion, 21(4), 562–566. https://doi.org/10.1037/emo0000638 Chirico, A., & Yaden, D. B. (2018). Awe: A self-transcendent emotion. Frontiers in Psychology, 9, Article 2353. https://doi.org/10.3389/fpsyg.2018.02353 International Dark-Sky Association (DarkSky) & NASA. (n.d.). Light pollution and night sky brightness data. NASA Earth Observatory / DarkSky International. https://darksky.org/resources/ or https://earthobservatory.nasa.gov/features/NightLights Keltner, D. (2023). Awe: The new science of everyday wonder and how it can transform your life. Penguin Press. https://www.penguinrandomhouse.com/books/622177/awe-by-dacher-keltner/ Keltner, D., & Haidt, J. (2003). Approaching awe, a moral, spiritual, and aesthetic emotion. Cognition and Emotion, 17(2), 297–314. https://doi.org/10.1080/02699930302297 Louv, R. (2008). Last child in the woods: Saving our children from nature-deficit disorder. Algonquin Books. http://richardlouv.com/books/last-child/ Piff, P. K., Dietze, P., Feinberg, M., Stancato, D. M., & Keltner, D. (2015). Awe, the small self, and prosocial behavior. Journal of Personality and Social Psychology, 108(6), 883–899. https://doi.org/10.1037/pspi0000018 Pollan, M. (2018). How to change your mind: What the new science of psychedelics teaches us about consciousness, dying, addiction, depression, and transcendence. Penguin Press. https://michaelpollan.com/books/how-to-change-your-mind/ Rudd, M., Vohs, K. D., & Aaker, J. (2012). Awe expands people's perception of time, alters decision making, and enhances well-being. Psychological Science, 23(10), 1130–1136. https://doi.org/10.1177/0956797612438731 Shiota, M. N., Keltner, D., & Mossman, A. (2007). The nature of awe: Elicitors, appraisals, and effects on self-concept. Emotion, 7(4), 944–963. https://doi.org/10.1037/1528-3542.7.4.944 Stellar, J. E., John-Henderson, N., Anderson, C. L., Gordon, A. M., McNeil, G. D., & Keltner, D. (2015). Positive affect and markers of inflammation: Discrete positive emotions predict lower levels of proinflammatory cytokines. Emotion, 15(2), 129–133. https://doi.org/10.1037/emo0000033
In the second installment of our series on primary progressive aphasia (PPA), Dr. Rogan Magee discusses logopenic PPA. Show citations: Grossman M, Seeley WW, Boxer AL, et al. Frontotemporal lobar degeneration. Nat Rev Dis Primers. 2023;9(1):40. Published 2023 Aug 10. doi:10.1038/s41572-023-00447-0 Gorno-Tempini ML, Hillis AE, Weintraub S, et al. Classification of primary progressive aphasia and its variants. Neurology. 2011;76(11):1006-1014. doi:10.1212/WNL.0b013e31821103e6 Santos-Santos MA, Rabinovici GD, Iaccarino L, et al. Rates of Amyloid Imaging Positivity in Patients With Primary Progressive Aphasia. JAMA Neurol. 2018;75(3):342-352. doi:10.1001/jamaneurol.2017.4309 Mandelli ML, Lorca-Puls DL, Lukic S, et al. Network anatomy in logopenic variant of primary progressive aphasia. Hum Brain Mapp. 2023;44(11):4390-4406. doi:10.1002/hbm.26388 Putcha D, Erkkinen M, Daffner KR. Functional Neurocircuitry of Cognition and Cognitive Syndromes. In: Silbersweig DA, Safar LT, Daffner KR. eds. Neuropsychiatry and behavioral neurology: principles and practice. McGraw Hill; 2021. Accessed November 6, 2025. https://neurology.mhmedical.com/content.aspx?bookid=3007§ionid=253215676 Montembeault M, Brambati SM, Gorno-Tempini ML, Migliaccio R. Clinical, Anatomical, and Pathological Features in the Three Variants of Primary Progressive Aphasia: A Review. Front Neurol. 2018;9:692. Published 2018 Aug 21. doi:10.3389/fneur.2018.00692 Clark DG. Frontotemporal Dementia. Continuum (Minneap Minn). 2024;30(6):1642-1672. doi:10.1212/CON.0000000000001506
In this episode of K9's Talking Scents, Cameron Ford sits down with world-renowned trainer Michael Ellis for one of the most in-depth conversations ever recorded on reinforcement theory, over-arousal, odor commitment, reward schedules, and why many detection dog programs unintentionally create false alerts.Together they break down the problems behind “reward-rich” training systems, how reinforcement can become punishing, why omission matters, and how to build dogs who persist, stay committed to odor, and search with accuracy — even in operational environments where rewards rarely come.This episode covers:• Why dogs become toy-obsessed instead of odor-committed• How handlers accidentally create false alerts• Why “continuous reinforcement” destroys operational reliability• Rewarding search vs rewarding finds• The science of frustration, dopamine, and over-performance• The difference between learning behavior and maintaining behavior• Why real-world deployments MUST be represented during training• How to introduce blanks, variable schedules, and expectation violation• "Satan's Infinite Loop" and how trainers build bad habits into dogs• Why many dogs don't indicate because they want the search to continue• How to build persistent, reliable, stable detection dogsIf you're a detection dog handler, trainer, supervisor, or K9 program manager, this is a masterclass.CHAPTERS00:00 — Intro & catching up01:00 — Online education & training libraries02:00 — Are rewards harming performance?05:00 — Reinforcement vs intrinsic motivation07:00 — Over-arousal in detection dogs08:30 — Searching for toys vs searching for odor10:00 — False alerts & frustration12:00 — The “cheat code” problem14:30 — Reward-rich environments vs real deployments17:00 — Continuous vs variable reinforcement19:00 — Training that mirrors real-world operations21:30 — Expectation violation & handler discomfort23:00 — Why easy training creates weak dogs26:00 — Dogs that quit vs dogs that persist28:00 — Reducing rewards without breaking the dog30:30 — Reading search behavior correctly32:00 — Consistency in training fundamentals35:00 — Foundation errors that create future problems38:00 — When to introduce blanks41:00 — Reinforcing end-of-search behaviors44:00 — Fixing continuously rewarded dogs47:00 — Why dogs miss the first odor49:00 — Over-arousal & compensation behaviors52:00 — Indication obsession & unintended consequences54:00 — Odor recognition vs sit/down behavior57:00 — Natural indications & reading the dog59:00 — Satan's Infinite Loop explained________________________________________
Clean air is free, so we ignore it. Air quality expert Mike Feldstein reveals why the thing we breathe most is the health pillar we optimize least.Full show notes and resources can be found here: jordanharbinger.com/1246What We Discuss with Mike Feldstein:L.A. wildfires created unprecedented contamination that lingered for weeks. 15,000+ homes and cars (including thousands of lithium batteries) burned, releasing toxic chemicals that kept fluctuating in the air six weeks later, with rain spreading toxins into soil and water rather than washing them away.Mold industry fear-mongering has created unnecessary panic. Many inspectors and naturopaths fuel anxiety about air quality, leading to expensive home remediation that may not be needed, forming a self-reinforcing ecosystem of concern.CO2 and oxygen levels in your home directly impact focus, mood, and performance. Poor ventilation affects everything from kids' classroom behavior to your sleep quality, yet we optimize diets and workouts while ignoring what we breathe 20,000+ times daily.We ignore air quality because it's free and abundant. Unlike food or water that require purchase and have immediate taste feedback, air seems invisible and consequence-free, making it the most overlooked pillar of health despite its constant impact.Improving air quality requires minimal daily effort for maximum health impact. Unlike meditation, journaling, or gym routines, clean air doesn't demand willpower every day, making it one of the most accessible ways to boost cognition, sleep, and recovery.And much more...And if you're still game to support us, please leave a review here — even one sentence helps! Sign up for Six-Minute Networking — our free networking and relationship development mini course — at jordanharbinger.com/course!Subscribe to our once-a-week Wee Bit Wiser newsletter today and start filling your Wednesdays with wisdom!Do you even Reddit, bro? Join us at r/JordanHarbinger!This Episode Is Brought To You By Our Fine Sponsors: Function Health: $100 credit: functionhealth.com/jordan, code JORDAN100Caldera + Lab: 20% off: calderalab.com/jordan, code JORDANJaspr: 25% off: jaspr.co/jordan, code JORDANAirbnb: Turn your house into a host: airbnb.com/hostShopify: 3 months @ $1/month (select plans): shopify.com/jordanSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
In the first part of this series, Dr. Rogan Magee provides an introduction to primary progressive aphasia (PPA) and explains its three subtypes. Show citations: Grossman M, Seeley WW, Boxer AL, et al. Frontotemporal lobar degeneration. Nat Rev Dis Primers. 2023;9(1):40. Published 2023 Aug 10. doi:10.1038/s41572-023-00447-0 Gorno-Tempini ML, Hillis AE, Weintraub S, et al. Classification of primary progressive aphasia and its variants. Neurology. 2011;76(11):1006-1014. doi:10.1212/WNL.0b013e31821103e6 Santos-Santos MA, Rabinovici GD, Iaccarino L, et al. Rates of Amyloid Imaging Positivity in Patients With Primary Progressive Aphasia. JAMA Neurol. 2018;75(3):342-352. doi:10.1001/jamaneurol.2017.4309 Mandelli ML, Lorca-Puls DL, Lukic S, et al. Network anatomy in logopenic variant of primary progressive aphasia. Hum Brain Mapp. 2023;44(11):4390-4406. doi:10.1002/hbm.26388 Putcha D, Erkkinen M, Daffner KR. Functional Neurocircuitry of Cognition and Cognitive Syndromes. In: Silbersweig DA, Safar LT, Daffner KR. eds. Neuropsychiatry and behavioral neurology: principles and practice. McGraw Hill; 2021. Accessed November 6, 2025. https://neurology.mhmedical.com/content.aspx?bookid=3007§ionid=253215676 Montembeault M, Brambati SM, Gorno-Tempini ML, Migliaccio R. Clinical, Anatomical, and Pathological Features in the Three Variants of Primary Progressive Aphasia: A Review. Front Neurol. 2018;9:692. Published 2018 Aug 21. doi:10.3389/fneur.2018.00692 Clark DG. Frontotemporal Dementia. Continuum (Minneap Minn). 2024;30(6):1642-1672. doi:10.1212/CON.0000000000001506
- Book Generator Progress and Updates (0:11) - Interviews and Documentaries (3:42) - Financial Markets and Geopolitical Updates (5:44) - European Economic Collapse and Refugee Crisis (14:27) - Trump's Role and AI Job Replacement (23:13) - Patrick Byrne's Interview and Political Insights (52:40) - AI and Economic Implications (1:06:39) - Government's Role and Technological Advancements (1:18:43) - Philosophical Foundations of Government (1:20:23) - Technological Advancements and Government's Role (1:24:33) - Google's Role in Censorship and Surveillance (1:25:06) - The Rise of AI and Its Implications (1:42:26) - The Role of AI in Survival and Independence (1:42:42) - The Philosophical Implications of AI (2:14:45) - The Role of AI in Medicine (2:15:46) - The Ethical Implications of AI (2:25:35) - The Future of AI and Humanity (2:29:15) - Demonic Energy and AI Control (2:29:54) - Sexual Perversion and Robotics (2:33:39) - Consciousness vs. Cognition (2:37:29) - Morphic Resonance and Human Knowledge (2:46:09) - Healing and Morphic Fields (2:49:05) - Decentralized Knowledge and AI Tools (2:54:48) For more updates, visit: http://www.brighteon.com/channel/hrreport NaturalNews videos would not be possible without you, as always we remain passionately dedicated to our mission of educating people all over the world on the subject of natural healing remedies and personal liberty (food freedom, medical freedom, the freedom of speech, etc.). Together, we're helping create a better world, with more honest food labeling, reduced chemical contamination, the avoidance of toxic heavy metals and vastly increased scientific transparency. ▶️ Every dollar you spend at the Health Ranger Store goes toward helping us achieve important science and content goals for humanity: https://www.healthrangerstore.com/ ▶️ Sign Up For Our Newsletter: https://www.naturalnews.com/Readerregistration.html ▶️ Brighteon: https://www.brighteon.com/channels/hrreport ▶️ Join Our Social Network: https://brighteon.social/@HealthRanger ▶️ Check In Stock Products at: https://PrepWithMike.com
Recapping the Week 12 DFS slate, checking in on best ball/Eliminator sweats, and previewing MNF + the Thanksgiving slate.
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