Podcasts about Quercetin

Nutrition Nugget! Bite-sized bonus episodes offer tips, tricks and approachable science. This week, Jenn is talking about Moringa—the supplement that's suddenly flooding everyone's social media feeds. But is this ancient "miracle tree" actually worth the hype, or is it just another wellness trend that promises more than it can deliver? Jenn dives into the science (or lack thereof) behind moringa's claimed benefits for blood sugar, cholesterol, and inflammation. She reveals what the research shows, why most studies haven't even been conducted on humans, and whether it's worth spending your money on this trendy supplement. Plus, she shares some surprising cautions about who may not want to take it and why the quality of what you're buying might matter more than you think. Like what you're hearing? Be sure to check out the full-length episodes of new releases every Wednesday. Have an idea for a nutrition nugget? Submit it here: https://asaladwithasideoffries.com/index.php/contact/ RESOURCES:Become a Happy Healthy Hub MemberJenn's Free Menu PlanA Salad With a Side of FriesA Salad With A Side Of Fries MerchA Salad With a Side of Fries InstagramAbout Uncomplicating WellnessText ‘Book' to 833-801-0500Nutrition Nugget: GlutathioneNutrition Nugget: Non-Alcoholic Liver DiseaseKEYWORDS: Jenn Trepeck, Nutrition Nugget, Salad With A Side Of Fries, Health Tips, Wellness Tips, Moringa Oleifera, Antioxidants, Nutritional Supplements, Drumstick Tree, Bioactive Compounds, Oxidative Stress, Anti-Inflammatory Properties, Blood Sugar Balance, Cholesterol Levels, Nutrient Dense Foods, Herbal Remedies, Phytochemicals, Quercetin, Free Radicals, Chronic Disease Prevention, Supplement Regimen, Traditional Medicine, Vitamin Content, Mineral Absorption, Antinutrients, Health Coaching, Wellness Supplements, Superfood Trends, Liver Health, Metabolic Health, Heart Health, Blood Pressure Support, Natural Remedies, Dietary Supplements, Plant-Based Nutrition, Should I Add Moringa To My Supplement Regimen, What Are The Health Benefits Of Moringa Leaves

Dr. Emeran Mayer sits down with Taylor Bell, an Ivy League–educated former management consultant turned full-time YouTuber, for a candid conversation on authenticity, ambition, and the health consequences of living out of alignment with your true values.Through her story of leaving a high-pressure corporate career to pursue creative entrepreneurship, Taylor shares what it means to redefine success, listen to your inner voice, and create a life rooted in purpose and well-being.Together, they explore the psychological effects of cognitive dissonance, how chronic stress shows up in the body, especially through the brain-gut-microbiome system, and why self-trust and intentional living are essential for both mental and physical health.Dr. Mayer also discusses the physiological impact of chronic stress, the concept of allostatic load, and practical tools such as diaphragmatic breathing that can help restore balance and resilience in a world of constant pressure and comparison.Key Topics Covered:• The link between cognitive dissonance, stress, and physical health• How authenticity and purpose shape mental well-being• The hidden costs of over-optimization and burnout• Simple ways to live and work with greater intention• Why listening to your body is more powerful than tracking every metric• Breathing techniques to reset the nervous system and calm the mindThis episode is both inspiring and deeply practical — a reminder that true success isn't about constant achievement, but about alignment, fulfillment, and trusting the wisdom of your own body.As always, we invite you to share your thoughts in the comments and subscribe for more episodes exploring the science of brain–body health.This episode is brought to you by Mayer Nutrition. If you are interested in trying Synaptic Bloom, our high-potency Quercetin + supporting polyphenols blend, you can visit mayernutrition.com, and use our exclusive podcast discount code: MINDGUT for 10% off your first order!Connect with Dr. Mayer:Website: https://www.emeranmayer.comInstagram: https://www.instagram.com/emeranmayer/X (Twitter): https://www.twitter.com/emeranmayermdFacebook: https://www.facebook.com/EmeranMayerMD/LinkedIn: https://www.linkedin.com/in/emeranmayer/Chapters:0:00 - 2:30 Introduction2:30 - 4:59 Career Shift from Consulting to YouTuber4:59 - 7:25 Synchronicity & Self-Trust7:25 - 17:38 Cognitive Dissonance, Gut Feelings & Finding Your True Passion17:38 - 19:16 Passion & Happiness19:16 - 23:53 Career Stress & Stress Response System23:53 - 25:33 Sponsor: Mayer Nutrition25:33 - 31:05 We've Taken Health Optimization Too Far31:05 - 32:30 Keys to Health & Longevity32:30 - 36:38 Chronic Stress, Brain-Gut-Microbiome System, Allostatic Load36:38 - 41:47 Practical Tips to Better Adapt to Stress41:47 - 46:27 Breathing Techniques Dr. Mayer Teaches His Patients46:27 - 49:01 Closing Remarks, Advice to People Dealing with Career Changes

Dr. Emeran Mayer sits down with Taylor Bell, an Ivy League–educated former management consultant turned full-time YouTuber, for a candid conversation on authenticity, ambition, and the health consequences of living out of alignment with your true values.Through her story of leaving a high-pressure corporate career to pursue creative entrepreneurship, Taylor shares what it means to redefine success, listen to your inner voice, and create a life rooted in purpose and well-being.Together, they explore the psychological effects of cognitive dissonance, how chronic stress shows up in the body, especially through the brain-gut-microbiome system, and why self-trust and intentional living are essential for both mental and physical health.Dr. Mayer also discusses the physiological impact of chronic stress, the concept of allostatic load, and practical tools such as diaphragmatic breathing that can help restore balance and resilience in a world of constant pressure and comparison.Key Topics Covered:• The link between cognitive dissonance, stress, and physical health• How authenticity and purpose shape mental well-being• The hidden costs of over-optimization and burnout• Simple ways to live and work with greater intention• Why listening to your body is more powerful than tracking every metric• Breathing techniques to reset the nervous system and calm the mindThis episode is both inspiring and deeply practical — a reminder that true success isn't about constant achievement, but about alignment, fulfillment, and trusting the wisdom of your own body.As always, we invite you to share your thoughts in the comments and subscribe for more episodes exploring the science of brain–body health.This episode is brought to you by Mayer Nutrition. If you are interested in trying Synaptic Bloom, our high-potency Quercetin + supporting polyphenols blend, you can visit mayernutrition.com, and use our exclusive podcast discount code: MINDGUT for 10% off your first order!Connect with Dr. Mayer:Website: https://www.emeranmayer.comInstagram: https://www.instagram.com/emeranmayer/X (Twitter): https://www.twitter.com/emeranmayermdFacebook: https://www.facebook.com/EmeranMayerMD/LinkedIn: https://www.linkedin.com/in/emeranmayer/Chapters:0:00 - 2:30 Introduction2:30 - 4:59 Career Shift from Consulting to YouTuber4:59 - 7:25 Synchronicity & Self-Trust7:25 - 17:38 Cognitive Dissonance, Gut Feelings & Finding Your True Passion17:38 - 19:16 Passion & Happiness19:16 - 23:53 Career Stress & Stress Response System23:53 - 25:33 Sponsor: Mayer Nutrition25:33 - 31:05 We've Taken Health Optimization Too Far31:05 - 32:30 Keys to Health & Longevity32:30 - 36:38 Chronic Stress, Brain-Gut-Microbiome System, Allostatic Load36:38 - 41:47 Practical Tips to Better Adapt to Stress41:47 - 46:27 Breathing Techniques Dr. Mayer Teaches His Patients46:27 - 49:01 Closing Remarks, Advice to People Dealing with Career Changes

While we're making progress in TREATING cancer, worldwide cancer INCIDENCE is soaring, especially among young people; New guidelines for colon cancer screening urge earlier start at age 45; Rates of peanut allergy are declining as more parents follow revised advice to introduce nuts earlier to kids; What's with all the buzz about methylene blue? Legalization and stronger pot are creating an epidemic of ER visits for uncontrolled vomiting, debilitating abdominal pain; New smart toilet gives you a report card on your poop; When Zoloft doesn't work for anxiety.

Dr. Vaughn discusses:-Ticks & What To Do if You Get Bitten by One?-Lyme Disease & How to Treat It-The Importance of Phytonutrients-Quercetin-FlavonoidsTo find out how we can help you on your health journey, book a free 15-minute Discovery Call with one of our New Client Coordinators! Click the link: https://www.spiritofhealthkc.com/discoverycall For more health tips and information visit: https://www.spiritofhealthkc.com/To buy natural health supplements visit: http://store.spiritofhealthkc.com Facebook: https://www.facebook.com/SpiritofHealth/ Instagram: https://www.instagram.com/spiritofhealthkc/ Pinterest: https://www.pinterest.com/spiritofhealthkc/YouTube: https://www.youtube.com/channel/UCwRcNSxR3kMYi9wP8OmxlQQ Spotify: https://open.spotify.com/show/7yfBBUjWKk3yJ3auK71O7H?si=295c77ed21f14568&nd=1&dlsi=af01c00121ed4aed

Dr. Hoffman continues his conversation with Dr. Tania Dempsey.

Many challenging medical conditions defy treatment and challenge clinicians to come up with innovative solutions—Chronic Fatigue Syndrome, fibromyalgia, Lyme Disease, Multiple Chemical Sensitivity (MCS), Ehlers-Danlos Syndrome (EDS) and autoimmune conditions; add now the growing burden of patients with Long Covid and vaccine injury. Dr. Tania Dempsey specializes in treating these complicated chronic disorders. She has embraced and advanced a new paradigm based on addressing Mast Cell Activation Syndrome (MCAS). What is MCAS? How is it differentiated from ordinary allergies, and why are its symptoms so pervasive? What are its causes and triggers? What role for low-histamine diets? Antihistamines? Other novel medications? What nutritional supplements can facilitate its resolution? How does recognition of the contribution of MCAS facilitate treatment of patients suffering from Long Covid and vaccine injuries?

Quercetin – ein Name, der immer häufiger in der Gesundheitsforschung auftaucht. Aber was steckt wirklich hinter diesem sekundären Pflanzenstoff? In dieser HEALTH NERDS Deep Dive Folge gehen Podcast-Host Felix Moese und Gesundheitswissenschaftler Matthias Baum der Wirkung von Quercetin auf den Grund – einem Flavonoid, das in vielen Obst- und Gemüsesorten steckt, etwa in Äpfeln, Zwiebeln, Beeren oder Kapern. -- Quercetin wirkt als starkes Antioxidans: Es fängt freie Radikale ab, schützt Zellen vor oxidativem Stress und kann Entzündungsprozesse im Körper regulieren. Studien zeigen, dass es die Immunabwehr stärkt, Gefäße schützt und sogar die Regeneration nach körperlicher Belastung unterstützen kann. Besonders spannend: Quercetin wirkt im Zusammenspiel mit anderen Vitalstoffen wie Vitamin C, Zink oder Bromelain noch effektiver – eine Synergie, die das Immunsystem ganzheitlich stärkt. Matthias erklärt, warum die Bioverfügbarkeit entscheidend ist – also wie gut unser Körper Quercetin tatsächlich aufnehmen kann. Denn nicht jede Form wird gleich gut verwertet. Ernährung, Verdauung und Kombination mit anderen Stoffen spielen hier eine zentrale Rolle. Ob als natürlicher Zellschutz, zur Unterstützung bei Allergien oder zur allgemeinen Entzündungsreduktion: Quercetin gilt als vielseitiger Schutzstoff für Körper und Geist. HEALTH NERDS. Mensch, einfach erklärt. -- Spare 15% auf Deine erste Bestellung auf https://artgerecht.com mit dem Code: HEALTHNERDS15 (im Warenkorb eingeben) -- Ein ALL EARS ON YOU Original Podcast.

Synthetic progestogens hike risk for brain tumors, natural progesterone safe; Healthy microbiome, good genes, clean lifestyle propel world's oldest woman to age 117; Can you take too much selenium? Cannabis extract scores vs. low back pain; Can vitamin K prevent breast calcifications? Are we making progress vs. pancreatic cancer? 

Extending our healthy years isn't just about eating well and exercising — it's also about the systems around us. Social policies, public health programs, and access to care all play a huge role in how long and how well we live. In this episode, we look at what it takes to improve health for everyone, everywhere. We each have personal choices to make, but what about the bigger picture?Dr. Tyler Evans is a physician, infectious disease specialist, and author of Pandemics, Poverty and Politics: Decoding the Social and Political Drivers of Pandemics from Plague to Covid-19.In a wide-ranging conversation with Peter Bowes, Dr. Evans connects stalled life expectancy to weakened safety nets, unequal access to healthcare, and the cracks exposed by recent global crises. He emphasizes practical action — meeting people where they are, funding prevention, and rebuilding systems that can spot and stop health threats early. Drawing on his experience from Los Angeles's Skid Row to global epidemic response, Evans calls for a non-partisan, evidence-driven approach that focuses on those most at risk — because when the most vulnerable communities thrive, everyone benefits.----This podcast is supported by affiliate arrangements with a select number of companies. We have arranged discounts on certain products and receive a small commission on sales. The income helps to cover production costs and ensures that our interviews remain free for all to listen. Visit our SHOP for more details: https://healthspan-media.com/live-long-podcast/shop/ PartiQlar supplementsEnhance your wellness journey with PartiQlar supplements. No magic formulas, just pure single ingredients, like NMN, L-Glutathione, Spermidine, Resveratrol, TMG and Quercetin. Get a 15% discount with the code MASTERAGING15 at PartiQlarEnergyBits algae snacksA microscopic form of life that could help us age better. Use code LLAMA for a 20 percent discountSiPhox Health home blood testingMeasure 17 critical blood biomarkers from home. Get a 20% discount with code LLAMA Disclaimer: This post contains affiliate links. If you make a purchase, I may receive a commission at no extra cost to you.Support the showThe Live Long and Master Aging (LLAMA) podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice. If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.

"Inflammaging: Woran merke ich chronische Entzündung im Alltag – und welche Blutwerte sollte ich checken?" "Blockiert Sonnencreme die Pre-Vitamin-D3-Synthese – oder nicht?" "Ich bin 42, zwei Kids, Vollzeitjob, wenig Schlaf: Welche 2–3 Supplements sollte ich als unbedingt nehmen?" "Für mich als Veganer - welche Longevity-Basic-Supplements sind aus eurer Sicht Pflicht?” "Kann man zu viel supplementieren – und wo lauern echte Risiken?" "Wird es irgendwann die eine, individuell zugeschnittene ‚Alles-drin‘-Pille geben – ein einziges Supplement für alles?" – vielen Dank für Eure Fragen zu unserer aktuellen Podcast-Episode "Longevity-Hype: Diese Supplements beeinflussen die biologischen Alterungsprozesse messbar". Matthias Baum aus dem HEALTH NERDS Wissenschaftsteam liefert hier in der Sprechstunde Antworten. -- Zur Hauptfolge: „Wir müssen verstehen, dass einer der Mechanismen, der zentral mit Alterung in Verbindung steht, chronische Entzündung ist.“ – Länger leben ist eine Sache – länger gesund leben eine ganz andere. In dieser HEALTH NERDS Episode schauen wir auf die Frage: Welche Supplements können biologische Alterungsprozesse tatsächlich beeinflussen – und wo endet der Hype? Wir sprechen über zentrale Mechanismen des Alterns wie Zellenergie, zelluläre Müllabfuhr durch Autophagie, Entzündungsregulation und die Rolle der Darmflora. Und wir ordnen ein, welche Stoffe die Wissenschaft aktuell diskutiert – von Omega-3, Vitamin D3, K2 und Magnesium bis zu Spermidin, NAD, Resveratrol, Quercetin, Q10/PQQ und Glycin. Und: Natürlich gehört auch Lactoferrin in die Reihe der vielversprechenden Game-Changer beim Thema gesund alt werden. "Im Kern geht es um die 'Kraftwerke' unserer Zellen, um Recycling- und Reparaturprozesse und um Stoffwechselwege, die Entzündung dämpfen – das sind die Stellschrauben, an denen sich Alterung verlangsamen lässt." -- Außerdem: Welche Substanzen zahlen auf welche Mechanismen ein, wo ist die Evidenz solide, wo ist sie noch dünn, und was bedeutet Bioverfügbarkeit in der Praxis? Wir sprechen über sinnvolle Dosierungen, Einnahmefenster, Qualität und mögliche Wechselwirkungen – ohne Heilsversprechen und ohne Dogmen. Klar ist: Supplements sind Verstärker, keine Ersatzspieler. Das Fundament bleibt Ernährung, Bewegung, Schlaf und Stressmanagement. -- Die Wissenschaft versteht immer besser, wie unser Körper altert – und vor allem, wie und mit welchen Nahrungsergänzungsmitteln wir diese Prozesse verlangsamen können. HEALTH NERDS. Mensch, einfach erklärt. -- Ein ALL EARS ON YOU Original Podcast.

Benadryl's active ingredient, diphenhydramine, is now considered outdated and unsafe, with researchers urging that it be removed from over-the-counter use The drug causes strong sedation, impaired memory, and slower reaction times, with studies showing it affects driving performance more than alcohol Older adults face lingering grogginess for up to 18 hours, while children risk unpredictable reactions, including agitation, coma, or heart problems if overdosed Other countries have already restricted access, and medical authorities warn against its use in children, highlighting safer alternatives and lifestyle strategies Natural approaches like vitamin C, quercetin, whole foods, restorative sleep, and stress management help balance histamine and reduce allergy symptoms without dangerous side effects

Dr. Emeran Mayer welcomes Peter Crone, widely known as The Mind Architect, for a profound conversation on healing trauma, dissolving limiting subconscious beliefs, and unlocking human potential.Peter shares how early life experiences shape the subconscious mind, often creating patterns of fear, anxiety, and self-judgment that hold us back. He explains how shifting awareness and reframing our narratives can open the door to greater freedom, love, and authentic living. Their dialogue bridges Eastern philosophy with modern psychology, offering practical steps to move beyond suffering into resilience and possibility.You'll also hear how the science of the subconscious intersects with personal transformation, and why cultivating presence can help us break free from being controlled by the past or the future.Key Topics Covered:• Letting go of past and future narratives that shape behavior• The roots of feeling “not good enough” and how to transcend it• Redefining peace as success through radical acceptance• Insights from Eastern philosophy and modern psychology• How trauma imprints the subconscious and shapes behavior• Living with more presence, authenticity, and easeThis episode is both a roadmap and an invitation. By releasing limiting beliefs and healing hidden wounds, we can expand into our fullest human potential.As always, please leave any questions or comments below.We hope you enjoy the episode!This episode is brought to you by Mayer Nutrition. If you are interested in trying Synaptic Bloom, our high-potency Quercetin + supporting polyphenols blend, you can visit mayernutrition.com & use our exclusive podcast discount code MINDGUT for 10% off your first order.Connect with Dr. Mayer:Website: https://www.emeranmayer.comInstagram: https://www.instagram.com/emeranmayerX: https://www.x.com/emeranmayermdFacebook: https://www.facebook.com/EmeranMayerMD/LinkedIn: https://www.linkedin.com/in/emeranmayer/Chapters:00:00 – Introduction01:32 – Peter Crone's journey and life lessons04:56 – Spirituality, Buddhism, and Eastern influences11:36 – Living in the present and letting go of the past19:13 – Trauma, healing, and the power of choice25:55 – Reprogramming the subconscious mind29:14 – Advertisement: Mayer Nutrition30:51 – Why we feel “not good enough”33:32 – Success, suffering, and hidden drivers of achievement36:41 – Personal reflections and growth37:38 – Psychedelics and altered states of awareness44:27 – The brain as a prediction machine51:26 – Aging, vitality, and redefining time56:14 – Closing thoughts

Dr. Emeran Mayer welcomes Peter Crone, widely known as The Mind Architect, for a profound conversation on healing trauma, dissolving limiting subconscious beliefs, and unlocking human potential.Peter shares how early life experiences shape the subconscious mind, often creating patterns of fear, anxiety, and self-judgment that hold us back. He explains how shifting awareness and reframing our narratives can open the door to greater freedom, love, and authentic living. Their dialogue bridges Eastern philosophy with modern psychology, offering practical steps to move beyond suffering into resilience and possibility.You'll also hear how the science of the subconscious intersects with personal transformation, and why cultivating presence can help us break free from being controlled by the past or the future.Key Topics Covered:• Letting go of past and future narratives that shape behavior• The roots of feeling “not good enough” and how to transcend it• Redefining peace as success through radical acceptance• Insights from Eastern philosophy and modern psychology• How trauma imprints the subconscious and shapes behavior• Living with more presence, authenticity, and easeThis episode is both a roadmap and an invitation. By releasing limiting beliefs and healing hidden wounds, we can expand into our fullest human potential.As always, please leave any questions or comments below.We hope you enjoy the episode!This episode is brought to you by Mayer Nutrition. If you are interested in trying Synaptic Bloom, our high-potency Quercetin + supporting polyphenols blend, you can visit mayernutrition.com & use our exclusive podcast discount code MINDGUT for 10% off your first order.Connect with Dr. Mayer:Website: https://www.emeranmayer.comInstagram: https://www.instagram.com/emeranmayerX: https://www.x.com/emeranmayermdFacebook: https://www.facebook.com/EmeranMayerMD/LinkedIn: https://www.linkedin.com/in/emeranmayer/Chapters:00:00 – Introduction01:32 – Peter Crone's journey and life lessons04:56 – Spirituality, Buddhism, and Eastern influences11:36 – Living in the present and letting go of the past19:13 – Trauma, healing, and the power of choice25:55 – Reprogramming the subconscious mind29:14 – Advertisement: Mayer Nutrition30:51 – Why we feel “not good enough”33:32 – Success, suffering, and hidden drivers of achievement36:41 – Personal reflections and growth37:38 – Psychedelics and altered states of awareness44:27 – The brain as a prediction machine51:26 – Aging, vitality, and redefining time56:14 – Closing thoughts

Perfect Aminos®️ vs. protein powders—which are better to stave off frailty? Cocoa extract supplements reduce age-related inflammation, and may curb chronic diseases; Being too skinny associated with higher risk of dying; One in eight Americans have tried GLP-1 drugs—but only half stick to them after one year, citing price, side effects; The many health benefits of saunas; Air pollution hikes cardiometabolic risk—as does harmful mouth bacteria; Is the flu shot truly a “vaccine” if it's only partially effective and has to be taken every year?

„Wir müssen verstehen, dass einer der Mechanismen, der zentral mit Alterung in Verbindung steht, chronische Entzündung ist.“ – Länger leben ist eine Sache – länger gesund leben eine ganz andere. In dieser HEALTH NERDS Folge schauen wir auf die Frage: Welche Supplements können biologische Alterungsprozesse tatsächlich beeinflussen – und wo endet der Hype? Wir sprechen über zentrale Mechanismen des Alterns wie Zellenergie, zelluläre Müllabfuhr durch Autophagie, Entzündungsregulation und die Rolle der Darmflora. Und wir ordnen ein, welche Stoffe die Wissenschaft aktuell diskutiert – von Omega-3, Vitamin D3, K2 und Magnesium bis zu Spermidin, NAD, Resveratrol, Quercetin, Q10/PQQ und Glycin. Und: Natürlich gehört auch Lactoferrin in die Reihe der vielversprechenden Game-Changer beim Thema gesund alt werden. "Im Kern geht es um die 'Kraftwerke' unserer Zellen, um Recycling- und Reparaturprozesse und um Stoffwechselwege, die Entzündung dämpfen – das sind die Stellschrauben, an denen sich Alterung verlangsamen lässt." -- Außerdem: Welche Substanzen zahlen auf welche Mechanismen ein, wo ist die Evidenz solide, wo ist sie noch dünn, und was bedeutet Bioverfügbarkeit in der Praxis? Wir sprechen über sinnvolle Dosierungen, Einnahmefenster, Qualität und mögliche Wechselwirkungen – ohne Heilsversprechen und ohne Dogmen. Klar ist: Supplements sind Verstärker, keine Ersatzspieler. Das Fundament bleibt Ernährung, Bewegung, Schlaf und Stressmanagement. -- Die Wissenschaft versteht immer besser, wie unser Körper altert – und vor allem, wie und mit welchen Nahrungsergänzungsmitteln wir diese Prozesse verlangsamen können. HEALTH NERDS. Mensch, einfach erklärt. -- Ein ALL EARS ON YOU Original Podcast.

On this episode of Vitality Radio, we tackle one of the most overlooked and misunderstood health concerns of our time: Histamine Intolerance and Mast Cell Activation Syndrome (MCAS). These conditions often appear with “mystery symptoms” like skin issues, digestive discomfort, headaches, fatigue, and strange food or chemical reactions—many of which have surged in the post-COVID era. Jared explains what histamine really is, why your body sometimes produces too much of it, and how mast cells can become overactive, creating a flood of inflammation. You'll learn about the role of DAO (Diamine Oxidase), the enzyme that helps break down food-based histamine, and why supplementing it can be a game-changer for many. You'll also hear about supportive tools and practical strategies to lower your histamine load, calm mast cells, and rebuild gut health. If you've been dismissed, told it's “just anxiety,” or left without answers, this episode offers clarity, hope, and practical steps to explore. Relief is possible—and it starts with understanding the root cause.Products DiscussedAdditional Information:DAO Blog Post with High Histamine Food ListVisit the podcast website here: VitalityRadio.comYou can follow @vitalitynutritionbountiful and @vitalityradio on Instagram, or Vitality Radio and Vitality Nutrition on Facebook. Join us also in the Vitality Radio Podcast Listener Community on Facebook. Shop the products that Jared mentions at vitalitynutrition.com. Let us know your thoughts about this episode using the hashtag #vitalityradio and please rate and review us on Apple Podcasts. Thank you!Just a reminder that this podcast is for educational purposes only. The FDA has not evaluated the podcast. The information is not intended to diagnose, treat, cure, or prevent any disease. The advice given is not intended to replace the advice of your medical professional.

In this encore episode, we detail hypochlorhydria while reviewing gastric lining anatomy, highlighting hydrochloric acid (HCl) secretion and its role in digestion, micronutrient absorption, and microbial defense. We discuss potential downstream effects of hypochlorhydria, including impaired digestive signaling, bacterial overgrowth in the small intestine (SIBO), and more. Lastly, we detail upstream microbial control, focusing on possible influences of the oral microbiome and oral dysbiosis.Topics: 1. Introduction- Highlighting the stomach and hypochlorhydria / low stomach acid, as well as microbial balance, dysbiosis, and overgrowth.- Discussion of intestinal microbiome and oral microbiome. 2. Gastric Anatomy and Mucosal Layers- The stomach: cardia, fundus, body, pylorus.- The gastric mucosa: epithelial lining, lamina propria, muscularis mucosae.- The epithelial layer: mucous cells, parietal cells, chief cells, enteroendocrine cells.- Beneath the mucosa: submucosa and muscular layers that contribute to gastric motility, mechanical digestion, and more. 3. Mucous Cells - The surface epithelium and gastric pits.- Secretion of thick, viscous mucus.- Protecting the epithelium.- The mucus traps bicarbonate ions: neutral microenvironment that protects against acid-induced damage. 4. Parietal Cells and Gastric Acid Secretion- Secretion of hydrochloric acid (HCl): denatures dietary proteins, sterilizes ingested food.- Parietal cells produce intrinsic factor: binds vitamin B12 to facilitate absorption in the ileum. 5. Chief Cells and Pepsinogen- Secretion of pepsinogen: activated by low pH into the proteolytic enzyme pepsin.- Pepsin and protein digestion.- Release of gastric lipase. 6. Hydrochloric Acid: Digestive and Protective Roles- Immune defense.- Pepsinogen activation.- Adequate gastric acidity essential for properly acidified chyme.- Priming release of bile and pancreatic enzymes. 7. The Small Intestine, Stomach, and Microbial Regulation- The pyloric sphincter.- The stomach supports minimal microbial diversity.- Acidic barrier aids in limiting the entry of opportunistic microbes into the small intestine. 8. Hypochlorhydria, Low Stomach Acid- Hypochlorhydria can compromise one of the body's defense mechanisms.- Colonization of the small intestine.- Insufficient pepsinogen activation and possible protein digestion impairment.- Suboptimal chyme formation and downstream digestive capacity.- Possible symptoms of hypochlorhydria.- Possible impaired absorption of micronutrients including vitamin B12, iron, calcium, magnesium.- H. pylori infection, autoimmunity, aging. 9. The Oral Microbiome, Intestinal Microbiome, and Dysbiosis- Oral and environmental microbes.- Altered gastric pH, bile, digestive enzymes, and more.- The oral cavity as the gateway to the GI tract.- Oral microbial species.- Oral hygiene and oral microbiome health. 10. Conclusion- Root-cause approach.Thank you to our episode sponsor: 1. ⁠⁠⁠⁠⁠⁠⁠⁠OmneDiem®'s⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠Histamine Digest®⁠⁠⁠⁠⁠⁠⁠⁠ and ⁠⁠⁠⁠⁠⁠⁠⁠Histamine Digest® PureMAX⁠⁠⁠⁠⁠⁠⁠⁠ : Use code STXAL9VI for 15% off.2. ⁠⁠⁠⁠⁠⁠⁠⁠Histamine Digest® Histamine Complete⁠⁠⁠⁠⁠⁠⁠⁠ with DAO, Vitamin C, Quercetin, Bromelain, and Stinging Nettle Root Extract: Use code STXAL9VI for 15% off.Get Chloe's Book Today! "⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠75 Gut-Healing Strategies & Biohacks⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠" Follow Chloe on Instagram ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@synthesisofwellness⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Visit ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠synthesisofwellness.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

Join us for our Histamine and Hormones Training on September 28th!Why do some women feel amazing during certain phases of their cycle while others feel absolutely wrecked?In this episode, I'm joined by Michelle Shapiro, RD, a functional dietitian who works with clients navigating Mast Cell Activation Syndrome (MCAS) and histamine issues. She also lives with MCAS herself, bringing both professional insight and personal experience to the table.Why do histamine flares hit hardest right when hormones shift? Tune in as we break down the menstrual cycle, step by step, and look at how mast cells and histamines interact with rising and falling hormones. The patterns aren't always what you'd expect, and tracking them can change everything about how you handle symptoms.You'll Learn:The role of mast cells in the immune system and why histamine release can trigger so many symptomsThe link between rising estrogen and increased histamine releaseWhy people with histamine issues can have paradoxical hormone symptomsHow long histamines actually stay in your system, and ways to avoid long-term sufferingWhat happens when conditions like POTS and hypermobility overlap with histamine issues during the cyclePractical strategies for tracking cycle patterns to spot histamine-driven flaresThe debate around antihistamines, pregnancy, and de-stigmatizing medication for symptom reliefWhy lowering histamines must come before deeper root-cause work like gut or mineral protocolsThe connection between histamines, mast cells, and endometriosisTimestamps:[00:00] Introduction[10:17] How estrogen and histamine interact to trigger symptoms during the menstrual cycle[13:53] How progesterone and luteal phase shifts trigger unexpected symptoms in histamine, POTS, and hypermobility clients[21:47] Tracking cycles and temperatures to spot patterns and histamine flares[25:53] Using antihistamines and other strategies to manage flares and reduce stigma around medication[48:09] Understanding the immune system's role in endometriosis and its connection to histamine and progesteroneListen to Other Hormone Healing Episodes with Michelle:MCAS, POTS, & Hypermobility Part 1 | Listen HereMCAS, POTS, & Hypermobility Part 2 | Listen HereThe Root Cause of Reflux | Listen HereResources Mentioned:Ovia Cycle-tracking App | WebsiteNatural Cycles Fertility Awareness App | WebsiteOura Ring | WebsiteTempdrop Wearable Sensor | WebsiteRead Your Body App | WebsitePodcast with Nina Boyce on Fertility Awareness Method | PodcastFind more from Michelle:Michelle Shapiro RD | InstagramMichelle Shapiro RD | WebsiteMichelle Shapiro Nutrition | YouTubeFind more from Amanda:Hormone Healing RD | InstagramHormone Healing RD | WebsiteHormone Healing RD | FacebookHormone Healing RD | YouTubeHormone Healing RD | TikTok

In this encore episode, we detail hydrogen sulfide (H₂S)-dominant small intestinal bacterial overgrowth (SIBO), focusing on intestinal motility. We briefly review anatomy, focusing on and detailing the interplay between structures supporting motility. Lastly, we detail possible symptoms of hydrogen sulfide-dominant SIBO as well as possible overlap between or among subtypes.Topics:1. Introduction to Hydrogen Sulfide-Dominant SIBO     - Overview of hydrogen sulfide (H₂S) SIBO    - H₂S production - Sulfur-containing amino acids   - Physiological roles of H₂S vs. in excess   2. Hydrogen Sulfide and Gastrointestinal Motility     - Possible impact on transit    - Possible association with IBS-like symptoms in excess 3. Anatomy: Intestinal Motility     - ENS as the "second brain"     - Myenteric and submucosal plexuses: regulation of peristalsis, secretion, blood flow     - Gut-brain axis involvement   - ICCs as pacemaker cells    - MMC's role in clearing debris and bacteria 4. Dysregulated Motility and SIBO5. Overlap Across SIBO Subtypes     - Possible symptoms   - Hydrogen and H₂S-dominant SIBO vs. IMO  6. Gastric Acid and Its Role    - HCl secretion by parietal cells and its role in digestion and microbial defense     - Hypochlorhydria  7. Conclusion   - Root cause approach.Thank you to our episode sponsor: 1. ⁠⁠⁠⁠⁠⁠⁠OmneDiem®'s⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠Histamine Digest®⁠⁠⁠⁠⁠⁠⁠ and ⁠⁠⁠⁠⁠⁠⁠Histamine Digest® PureMAX⁠⁠⁠⁠⁠⁠⁠ : Use code STXAL9VI for 15% off.2. ⁠⁠⁠⁠⁠⁠⁠Histamine Digest® Histamine Complete⁠⁠⁠⁠⁠⁠⁠ with DAO, Vitamin C, Quercetin, Bromelain, and Stinging Nettle Root Extract: Use code STXAL9VI for 15% off.Get Chloe's Book Today! "⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠75 Gut-Healing Strategies & Biohacks⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠" Follow Chloe on Instagram ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@synthesisofwellness⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Visit ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠synthesisofwellness.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

In this encore episode, we highlight the stomach's role in vitamin B12 absorption and bioavailability, detailing the cellular composition of the gastric mucosa and further highlighting mucous cells, parietal cells, and chief cells. We also briefly discuss Helicobacter pylori and common symptoms, while detailing H. pylori's potential impacts on the gastric mucosal barrier. Topics:1. Introduction- Overview of the stomach's role in B12 absorption- Helicobacter pylori  2. H. pylori Overview- Gram-negative bacterium, can colonize the stomach lining- Many individuals remain asymptomatic- Symptoms - Can contribute to gastritis and peptic ulcers- Produces urease, hydrolyzes urea into ammonia (NH₃) andcarbon dioxide (CO₂)- Ammonia neutralizes stomach acid locally, protective microenvironment- H. pylori damages the mucosal barrier and contributes to persistence- Possesses additional virulence factors 3. Gastric Anatomy  -  Stomach is divided into the cardia, fundus, body, and pylorus- The gastric mucosa - The epithelial lining; mucous cells, parietal cells, chief cells, and more 4. Mucous Cells and Mucosal Protection  - Line the gastric pits and secrete thick, viscous mucus- Mucus composed of water, mucin glycoproteins, and other low-molecular-weight molecules- Traps bicarbonate ions (HCO₃⁻)- Shields the stomach lining 5. Parietal Cells  - Located in the gastric glands, predominantly in the fundus and body- Secrete hydrochloric acid (HCl)- Secrete intrinsic factor (IF) 6. Vitamin B12 Overview - Cobalamin: DNA synthesis, red blood cell formation, neurological function, methylation, and more- Methylcobalamin and 5-deoxyadenosylcobalamin- Non-active forms include hydroxocobalamin and synthetic cyanocobalamin   7. Vitamin B12 Absorption Pathway  - B12 is released from proteins by HCl and pepsin- Binds first to haptocorrin- In the small intestine, pancreatic enzymes degrade haptocorrin- B12 binds intrinsic factor - Absorption in the ileum - Impairment  8. Chief Cells  - Located in the gastric glands- Secrete pepsinogen, activated by acid into pepsin- Also secrete gastric lipase 9. Hydrochloric Acid (HCl) - Secreted by parietal cells- Denatures dietary proteins and activates pepsinogen- Acts as a defense mechanism by aiding in sterilizing ingested food 10. Relevance of H. pylori - Produces urease that breaks down urea into NH₃ and CO₂- Ammonia neutralizes acid locally, forming a protective “bubble”- Enhances mucosal damage and microbial persistence 11. B12 Absorption  - Multiple factors and root causes can impair absorption- H. pylori 12. Hypochlorhydria  - Symptoms- Absorption: vitamin B12, iron, calcium, magnesium, more- Small Intestinal Bacterial Overgrowth (SIBO)  13. Conclusion- Multi-factorial, root cause approachThank you to our episode sponsor: 1. ⁠⁠⁠⁠⁠⁠OmneDiem®'s⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠Histamine Digest®⁠⁠⁠⁠⁠⁠ and ⁠⁠⁠⁠⁠⁠Histamine Digest® PureMAX⁠⁠⁠⁠⁠⁠ : Use code STXAL9VI for 15% off.2. ⁠⁠⁠⁠⁠⁠Histamine Digest® Histamine Complete⁠⁠⁠⁠⁠⁠ with DAO, Vitamin C, Quercetin, Bromelain, and Stinging Nettle Root Extract: Use code STXAL9VI for 15% off.Thanks for tuning in!Get Chloe's Book Today! "⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠75 Gut-Healing Strategies & Biohacks⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠" Follow Chloe on Instagram ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@synthesisofwellness⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Follow Chloe on TikTok @chloe_c_porterVisit ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠synthesisofwellness.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ to purchase products, subscribe to our mailing list, and more!

In this episode, we are joined by Helmut Schmutz. Helmut developed the original, patented diamine oxidase formulation, and his work serves as a driving force in the innovation at OmneDiem. Topics: 1.  Histamine- Exogenous versus endogenous histamine.- Mast cells as a source of endogenous histamine.- Endogenous histamine signaling needed for diverse physiological functions.- Intestinal microbes as a source of histamine production.- Food as a source of histamine.2. Dietary Histamine- Foods higher in histamine.- Histamine in food and taste.- Histamine-rich foods and histamine liberators. 3. Histamine Intolerance- Intolerance versus sensitivity versus allergy- Hallmark symptoms of histamine intolerance.- Histamine intolerance and diamine oxidase enzyme insufficiency.4. Diamine Oxidase Supplementation- OmneDiem's enzyme preservation and HDUs.- Where the supplement acts; protection from the gastric environment.- Timing of supplementation.5.  Histamine and Women's Health- Hormonal fluctuations and effects on endogenous histamine release or clearance.- Menopause.6.  OmneDiemExplore ⁠⁠⁠⁠⁠OmneDiem®'s⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠Histamine Digest®⁠⁠⁠⁠⁠ and ⁠⁠⁠⁠⁠Histamine Digest® PureMAX⁠⁠⁠⁠⁠ : Use code STXAL9VI for 15% off.Explore ⁠⁠⁠⁠⁠Histamine Digest® Histamine Complete⁠⁠⁠⁠⁠ with DAO, Vitamin C, Quercetin, Bromelain, and Stinging Nettle Root Extract: Use code STXAL9VI for 15% off.Thanks for tuning in!Get Chloe's Book Today! "⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠75 Gut-Healing Strategies & Biohacks⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠" Follow Chloe on Instagram ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@synthesisofwellness⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Visit ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠synthesisofwellness.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

For weight loss, complete avoidance of ultra-processed foods outperforms mere “healthy diet” comprising minimally-processed items; Research fraud undermines anti-dementia drug pipeline; Comprehensive lifestyle modification program scores against cognitive decline; Women's brains especially vulnerable to Omega-3 deficiencies; Bible says “Lame shall walk again” and 21st century science may soon bring about this miracle; Breakthroughs in rheumatoid arthritis treatment.

How reliable is nutrition science?I have gingivitis, and my dentist recommended Listerine. Won't that disrupt the microbiome in my mouth?I take a diuretic for high blood pressure. Is it okay to stop drinking water by 8pm, or will I dehydrate?Is there a way to get rid of seborrheic keratoses?

How much leucine should I take to regain muscle?Should I increase my creatine dose to 10 grams daily for the cognitive benefits?You talked about the cancer risk of CT scans. What about CT angiograms?  I've had a ganglion cyst drained twice. How can I keep it from coming back?Who can I contact for treatment of mast cell activation syndrome?I heard you should brush your teeth with fluoride toothpaste if there's no fluoride in your drinking water 

Grandpa Bill's Brain Fuel: The Top Supplements Dr. Amen Recommends for a Healthier MindGrandpa Bill here. For the past few days, we've been on a mission to improve our brain health. We've talked about a great workout for the mind, but today, we're going to dive into what to feed it. Dr. Daniel Amen, a man who has looked at more brain scans than almost anyone, teaches us that you can't have a healthy mind without the right fuel. So, let's talk about his top supplement suggestions—the brain-boosting heroes you might want to add to your daily routine.Remember, always talk to your doctor before starting any new supplement. They're your co-pilot on this journey.If you think of your brain as a house, Omega-3s (like DHA and EPA) are the high-quality lumber. They are a core component of your brain cell membranes. Dr. Amen considers them foundational for memory, mood, and overall brain structure.This trio of B vitamins works together to create energy in the brain. They also help clear away a substance that can be harmful to our blood vessels, keeping the pathways clear for good blood flow. Think of them as the team that keeps the lights on in your mind, ensuring your brain has the juice to function optimally.Choline is a key nutrient your body uses to create a messenger for memory called acetylcholine. Having enough choline is like having a reliable mail carrier—it helps ensure that your memory messages get delivered quickly and accurately.You might think these are just for your stomach, but your gut is often called your "second brain." The healthy bacteria in your gut send signals to your mind that can help manage stress and anxiety. A happy gut often means a happier brain!Dr. Amen points to mushrooms like Cordyceps and Reishi. These are known as "adaptogens," meaning they help your body and brain handle stress more effectively. They don't create a buzz; they train your brain to be more resilient, like a personal trainer building strength.These are powerful compounds that fight inflammation throughout your body, including your brain. Inflammation can harm brain cells over time, so Curcumin and Quercetin act like a cleanup crew, reducing swelling and protecting your mind from damage.This one is crucial for everyone! Vitamin D is vital for mood and overall brain health. Studies show that a lack of Vitamin D is common and can be tied to feelings of sadness. Getting enough of this "sunshine vitamin" can make a world of difference.Rounding out the list, Saffron is a great mood booster, while Ginkgo Biloba helps promote healthy blood flow to the brain.So, there you have it, folks. By giving your brain the right fuel, you're not just taking supplements; you're building a healthier, happier you from the inside out.Keep that body and mind moving!1. Omega-3s (The Brain's Building Blocks)2. B12, B6 & Folate (The Power Plant)3. Choline (The Memory Messenger)4. Probiotics (The Gut-Brain Connection)5. "Smart Mushrooms" (Resilience Trainers)6. Curcumin & Quercetin (The Cleanup Crew)7. Vitamin D (The Sunshine Vitamin)8. Saffron & Ginkgo Biloba#supplements,#BrainHealth,#BrainSupplements,#DanielAmen,#HolisticHealth,#WorkoutsForGeriatrics,#WorkoutsForGeriatrics#SilverStreakers,#HealthyAging,#CognitiveHealth,#Wellness,#Nootropics,#GrandpaBill,

In this encore episode, we detail the oral-gut microbiota axis, detailing the oral microbiome and its relationship with the intestinal microbiome. We discuss the development of oral biofilm, the transition from plaque to dental calculus, and potential impacts of oral dysbiosis, while highlighting intestinal health and focusing on Fusobacterium nucleatum. Topics:1. Overview of the Oral Microbiome and the Oral-Gut Axis - The oral cavity and the gut: microbially dense sites. - Anatomically distinct but connected and capable of influencing each other. - The oral microbiome. - Microbial distribution: topography and chemistry of oral surfaces. 2. Oral Cavity Anatomy and Microenvironments - The vestibule and oral cavity proper. - Lined by oral mucosa, which varies in structure. - Unique ecological niches that support different microbial populations. 3. Tooth Structure and Relevance to Microbial Colonization - Teeth are embedded in the alveolar processes of the maxilla and mandible. - Tooth structure. - Long-term microbial colonization and biofilm development. 4. Biofilm / Dental Plaque Development - Biofilm begins with the formation of the acquired pellicle.- Pioneer species secreting extracellular polymeric substances (EPS).- Secondary colonizers coaggregate.- Coaggregation is species-specific.- Example.- Aerobes can lower local oxygen levels, creating micro anaerobic niches that support obligate anaerobes. 5. Maturation of the Biofilm  - Biofilm composition shifting to anaerobic, proteolytic species such as P. gingivalis. - F. nucleatum: a bridge species. 6. Mineralization and Formation of Dental Calculus - Mineralization, calcium and phosphate deposition. - Dental calculus. 7. Oral Dysbiosis  - An imbalance in the oral microbial community. - Potential signs and symptoms. - Halitosis, swollen or bleeding gums, tooth sensitivity. 8. Oral-Gut Axis and Systemic Implications - Physical, chemical, biochemical, and immunological barriers aid in preventing oral bacteria from colonizing the gut. - Oral bacteria can potentially impact intestinal health. -  F. nucleatum and IBD. 9. Oral Microbiome Testing10. Multi-Factorial Thank you to our episode sponsors: 1. ⁠⁠⁠⁠⁠OmneDiem®'s⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠Histamine Digest®⁠⁠⁠⁠⁠ and ⁠⁠⁠⁠⁠Histamine Digest® PureMAX⁠⁠⁠⁠⁠ : Use code STXAL9VI for 15% off.2. ⁠⁠⁠⁠⁠Histamine Digest® Histamine Complete⁠⁠⁠⁠⁠ with DAO, Vitamin C, Quercetin, Bromelain, and Stinging Nettle Root Extract: Use code STXAL9VI for 15% off.3. ⁠Codex Labs⁠: Explore Codex Labs' collections for ⁠acne⁠, ⁠eczema⁠, and more. Shop the ⁠BIA Collection HereGet Chloe's Book Today! "⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠75 Gut-Healing Strategies & Biohacks⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠" Follow Chloe on Instagram ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@synthesisofwellness⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Visit ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠synthesisofwellness.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

Report shows rapid declines in health of children and adolescents since 2007; N-acetylcysteine (NAC) for Parkinson's; Statins increase likelihood of hearing loss, tinnitus; Lithium orotate for Alzheimer's; Is tinnitus reversible? Novel implantable electrical vagus nerve stimulator approved for treatment of rheumatoid arthritis.

In this episode, we detail the structure and function of the intestinal mucosal barrier, highlighting key roles that zinc plays in supporting various aspects of mucosal barrier integrity. We detail key anatomical features, including the mucus layer, epithelial cells, and tight junctions, before discussing zinc's physiological roles, its relationship with copper, and factors that can affect zinc levels. The discussion further details mechanistic features of zinc absorption as well as specialized forms such as zinc carnosine.Topics:1. Introduction - Overview of intestinal hyperpermeability and intestinal barrier function- Highlighting the role of zinc 2. Intestinal Barrier Anatomy - Four major layers: mucosa, submucosa, muscularis externa, serosa- Mucosa subdivisions; focus on epithelium  3. The Mucus Layer  - Location over the epithelial surface- Composition: mucin-rich, secreted by goblet cells- Goblet cell mucin storage and expansion upon hydration- Functions: trapping pathogens, lubricating epithelium, housing molecules including secretory IgA- Small intestine mucus - Large intestine mucus 4. The Intestinal Epithelium - Monolayer of epithelial cells: enterocytes, goblet cells, and more- Tight junctions, paracellular transport - Continuous epithelial renewal 5. Introduction to Zinc - Zinc as a trace mineral required in minute quantities for numerous physiological processes - Second most abundant trace mineral after iron; majority stored in muscle and bone- Maintaining plasma and intracellular zinc concentrations within narrow range- Both deficiency and excess can disrupt biochemical processes 6. Zinc and Copper  - Zinc and copper as closely interconnected minerals- Zinc, copper, and metallothionein binding in enterocytes- Both high and low zinc can disrupt zinc-copper balance- Metallothionein as a cysteine-rich metal-binding protein  7. Factors Affecting Zinc Levels  - Multifactorial- Possible signs of low zinc status 8. Zinc Absorption  - Dietary sources- Primary absorption in small intestine - In the stomach: HCl and pepsin denature proteins and cleave peptide bonds, releasing zinc from protein complexes- Dietary zinc often bound within tertiary protein structure- Specialized transporters  9. Zinc's Role in the Intestinal Barrier  - Zinc and tight junction proteins- Zinc and Intestinal Epithelial Cells - Zinc and the mucus layer 10. Broader Context of Zinc in Physiology   11. Zinc Carnosine  - Molecular complex of zinc and carnosine- L-carnosine composed of beta-alanine and L-histidine- Gastrointestinal context 12. Conclusion - Multifactorial and multi-system.Thank you to our episode sponsors: 1. ⁠⁠⁠⁠OmneDiem®'s⁠⁠⁠⁠ ⁠⁠⁠⁠Histamine Digest®⁠⁠⁠⁠ and ⁠⁠⁠⁠Histamine Digest® PureMAX⁠⁠⁠⁠ : Use code STXAL9VI for 15% off.2. ⁠⁠⁠⁠Histamine Digest® Histamine Complete⁠⁠⁠⁠ with DAO, Vitamin C, Quercetin, Bromelain, and Stinging Nettle Root Extract: Use code STXAL9VI for 15% off.3. Codex Labs: Explore Codex Labs' collections for acne, eczema, and more. Shop the BIA Collection HereThanks for tuning in!Get Chloe's Book Today! "⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠75 Gut-Healing Strategies & Biohacks⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠" Follow Chloe on Instagram ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@synthesisofwellness⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Visit ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠synthesisofwellness.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

Protect Your Retirement with a PHYSICAL Gold and/or Silver IRA https://www.sgtreportgold.com/ CALL( 877) 646-5347 - You Can Trust Noble Gold. Dr. Peter McCullough returns to SGT Report to discuss the most harmful product ever devised by man, it's responsible for innumerable injuries and millions of deaths around the world and it's till on the market. In fact, the spike protein may be clotting YOUR blood whether you took this product or not. Join us to learn about the problem AND the fix.   Simplify (& MAXIMIZE) your HSA/FSA account & reimbursements HERE: https://wellnesspay.com/sgt   Get HEALTH CARE from HONEST Doctors at The Wellness Center: https://www.TWC.health/SGT GET the Zinc, Quercetin, Vitamin C & D we all NEED in Z-Stack: www.zstacklife.com/sgtreport Remove MAC codes, heavy metals, graphene oxide & nanotech from your blood w/ MaterPeace: https://masterpeacebyhcs.com/?ref=4094 https://rumble.com/embed/v6vbe7i/?pub=2peuz

A new study is challenging one of the most pervasive messages in health and fitness: the belief that 10,000 daily steps are needed to prolong life and prevent disease. Led by Professor Melody Ding at the University of Sydney and published in The Lancet, the study is the largest of its kind, analyzing data from more than 30 studies worldwide. Its findings suggest that significant health benefits may be achieved with as few as 7,000 steps a day—an attainable target for many who find 10,000 steps daunting. In this interview, Professor Ding discusses the scientific basis for rethinking our daily activity goals, how the research caught global attention, and what it means for public health recommendations moving forward. Peter Bowes speaks to Professor Ding to unpack what this shift in guidance could mean for millions tracking their steps around the world. PartiQlar supplementsEnhance your wellness journey with PartiQlar supplements. No magic formulas, just pure single ingredients, like NMN, L-Glutathione, Spermidine, Resveratrol, TMG and Quercetin. Get a 15% discount with the code MASTERAGING15 at PartiQlarEnergyBits algae snacksA microscopic form of life that could help us age better. Use code LLAMA for a 20 percent discountDisclaimer: This post contains affiliate links. If you make a purchase, I may receive a commission at no extra cost to you.Support the showThe Live Long and Master Aging (LLAMA) podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice. If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.

In this encore episode, we detail the gut-immune axis, focusing on the protective mucus layer and the roles of secretory immunoglobulin A and lactoferrin in intestinal health. We discuss endogenous secretions as well as highlight lactoferrin testing and levels. Topics: 1. The Intestinal Barrier & Mucus Layer- The intestinal lumen, microbiome, mucus layer, epithelial cells, and lamina propria.- The mucus layer: antimicrobial peptides (AMPs) and secretory IgA (sIgA).- Intestinal epithelial cells including goblet cells and enterocytes.2. Immune Cells in the Gut- The lamina propria.- Macrophages, dendritic cells, neutrophils, B cells, T cells, mast cells, and more.3. Antimicrobial Peptides & Secretory IgA- AMPs and sIgA in the mucus layer aid in regulating microbial balance and pathogen adhesion.4. Lactoferrin: Functions & Sources- Iron-binding glycoprotein, antimicrobial and immunomodulatory properties.- Found in mucosal secretions, colostrum, and more.- Intestinal epithelial cells (IECs) and neutrophils.5. Lactoferrin's Role in Intestinal Health- Regulates iron absorption via lactoferrin receptors (LFR)on enterocytes.- Sequesters free iron, limiting bacterial growth, bacteriostatic.- Destabilizes bacterial membranes, cell lysis, bactericidal.6. Lactoferrin Levels- Neutrophils release lactoferrin during infection,increasing its presence in the large intestine.- Fecal lactoferrin levels.- Fecal calprotectin levels.7. Candida Overgrowth8. Lactoferrin Supplementation to Support the Gut9. Conclusion- The intestinal mucus layer.- Lactoferrin.Thank you to our episode sponsor: 1. ⁠⁠⁠OmneDiem®'s⁠⁠⁠ ⁠⁠⁠Histamine Digest®⁠⁠⁠ and ⁠⁠⁠Histamine Digest® PureMAX⁠⁠⁠ 2. ⁠⁠⁠Histamine Digest® Histamine Complete⁠⁠⁠ with DAO, Vitamin C, Quercetin, Bromelain, and Stinging Nettle Root Extract.Thanks for tuning in!Get Chloe's Book Today! "⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠75 Gut-Healing Strategies & Biohacks⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠" Follow Chloe on Instagram ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@synthesisofwellness⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Visit ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠synthesisofwellness.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

In this episode Dr Sarah Howard discusses healthy ageing in dogs with Dr Matthew Muir. Topics discussed include: The reason ageing is currently a hot topic. What leads to an increased lifespan and better quality of life? Diet changes that can impact ageing in dogs. Dr Muir discusses what we should avoid in order to increase lifespan. Matthew goes into details of what dogs' diets should look like to prevent disease. How often should we be feeding our pets? What happens to the gut microbiome as dogs get older? Dr Muir delves into supplements that can be beneficial for ageing and emerging tools that are becoming available. The importance of preventative medicine - proactive vs reactive care. Accelerators of biological ageing. Additional resources: https://pubmed.ncbi.nlm.nih.gov/11991408/ https://pmc.ncbi.nlm.nih.gov/articles/PMC11675035/https://www.frontiersin.org/journals/veterinary-science/articles/10.3389/fvets.2024.1355560/full https://pmc.ncbi.nlm.nih.gov/articles/PMC11505706/ https://www.mdpi.com/1660-3397/18/11/564https://pmc.ncbi.nlm.nih.gov/articles/PMC4936929/ https://pubmed.ncbi.nlm.nih.gov/22216092/ Adams VJ, Watson P, Carmichael S, Gerry S, Penell J, Morgan DM. Exceptional longevity and potential determinants of successful ageing in a cohort of 39 Labrador retrievers: results of a prospective longitudinal study. Acta Vet Scand. 2016;58:29. doi:10.1186/s13028-016-0204-8 Cupp CJ, Jean-Philippe C, Kerr WW, Patil AR. Effect of nutritional interventions on longevity of senior cats. Int J Appl Res Vet Med. 2007;5(3):133–149 Bermingham EN, Patterson KA, Shoveller AK, Fraser K, Butowski CF, Thomas DG. Nutritional needs and health outcomes of ageing cats and dogs: is it time for updated nutrient guidelines? Anim Front. 2024;14(3):5–16. doi:10.1093/af/vfae008 Jackson J, Radford AD, Belshaw Z, Wallis LJ, Kubinyi E, German AJ, Westgarth C. Using veterinary health records at scale to investigate ageing dogs and their common issues in primary care. J Small Anim Pract. 2025;66(2):81–91. doi:10.1111/jsap.13809 Creevy KE, O'Neill DG, Promislow DEL. Morbidity and mortality in elderly dogs – a model for human aging. BMC Vet Res. 2022;18(1):456. doi:10.1186/s12917-022-03518-8 Lewis TW, Wiles BM, Llewellyn-Zaidi AM, Evans KM, O’Neill DG. Longevity and mortality in Kennel Club registered dog breeds in the UK in 2014. Canine Genet Epidemiol. 2018;5:10. doi:10.1186/s40575-018-0066-8 Kealy RD, Lawler DF, Ballam JM, Mantz SL, Biery DN, Greeley EH, Lust G, Segre M, Smith GK, Stowe HD. Effects of diet restriction on life span and age-related changes in dogs. J Am Vet Med Assoc. 2002;220(9):1315–1320. doi:10.2460/javma.2002.220.1315 Guelfi G, Capaccia C, Tedeschi M, Bufalari A, Leonardi L, Cenci-Goga B, Maranesi M. Dog aging: a comprehensive review of molecular, cellular, and physiological processes. Cells. 2024;13(24):2101. doi:10.3390/cells13242101 Laflamme DP. Nutritional care for aging cats and dogs. Vet Clin North Am Small Anim Pract. 2012;42(4):769–791. doi:10.1016/j.cvsm.2012.04.002 Hall JA, Jewell DE. Feeding healthy beagles medium-chain triglycerides, fish oil, and L-carnitine offsets age-related changes in serum fatty acids and carnitine metabolites. PLoS One. 2012;7(11):e49510. doi:10.1371/journal.pone.0049510 Bermingham EN, Patterson KA, Shoveller AK, Fraser K, Butowski CF, Thomas DG. Nutritional needs and health outcomes of ageing cats and dogs: is it time for updated nutrient guidelines? Anim Front. 2024;14(3):5–16. doi:10.1093/af/vfae008 Bray EE, Zheng Z, Tolbert MK, McCoy BM, Kaeberlein M, Kerr KF; Dog Aging Project Consortium. Once-daily feeding is associated with better health in companion dogs: results from the Dog Aging Project. GeroScience. 2022;44(3):1779–1790. doi:10.1007/s11357-022-00575-7 Palaseweenun P, Hagen‐Plantinga EA, Schonewille JT, Koop G, Butre C, Jonathan M, Wierenga PA, Hendriks WH. Urinary excretion of advanced glycation end products in dogs and cats. J Anim Physiol Anim Nutr (Berl). 2021;105(1):149–156. doi:10.1111/jpn.13347 Yang L, Yang L, Cai Y, Luo Y, Wang H, Wang L, Chen J, Liu X, Wu Y, Qin Y, Wu Z, Liu N. Natural mycotoxin contamination in dog food: a review on toxicity and detoxification methods. Ecotoxicol Environ Saf. 2023;257:114948. doi:10.1016/j.ecoenv.2023.114948 Bridglalsingh S, Archer-Hartmann S, Azadi P, Barbier de La Serre C, Remillard RL, Sunvold GD, Bartges JW. Association of four differently processed diets with plasma and urine advanced glycation end products and serum soluble receptor for advanced glycation end products concentration in healthy dogs. J Anim Physiol Anim Nutr (Berl). 2024;108(3):735–751. doi:10.1111/jpn.13927 Marchi PH, Vendramini THA, Perini MP, Zafalon RVA, Amaral AR, Ochamotto VA, Da Silveira JC, Dagli MLZ, Brunetto MA. Obesity, inflammation, and cancer in dogs: review and perspectives. Front Vet Sci. 2022;9:1004122. doi:10.3389/fvets.2022.1004122 Schmid SM, Hoffman JM, Prescott J, Ernst H, Promislow DEL, Creevy KE; Dog Aging Project Consortium. The companion dog as a model for inflammaging: a cross-sectional pilot study. GeroScience. 2024;46(6):5395–5407. doi:10.1007/s11357-024-01217-w Ren J, Li H, Zeng G, Pang B, Wang Q, Wei J. Gut microbiome-mediated mechanisms in aging-related diseases: are probiotics ready for prime time? Front Pharmacol. 2023;14:1178596. doi:10.3389/fphar.2023.1178596 Parker A, Romano S, Ansorge R, Aboelnour A, Le Gall G, Savva GM, Pontifex MG, Telatin A, Baker D, Jones E, Vauzour D, Rudder S, Blackshaw LA, Jeffery G, Carding SR. Fecal microbiota transfer between young and aged mice reverses hallmarks of the aging gut, eye, and brain. Microbiome. 2022;10:68. doi:10.1186/s40168-022-01262-3 Ulluwishewa D, Anderson RC, McNabb WC, et al. Regulation of tight junction permeability by intestinal bacteria and dietary components. J Nutr. 2011;141(5):769–76. doi:10.3945/jn.110.135657 Cao L, Lee SG, Lim KT, Kim HR. Potential anti-aging substances derived from seaweeds. Mar Drugs. 2020;18(11):564. doi:10.3390/md18110564 Grzeczka A, Graczyk S, Kordowitzki P. Pleiotropic effects of resveratrol on aging-related cardiovascular diseases—what can we learn from research in dogs? Cells. 2024;13(20):1732. doi:10.3390/cells13201732 Kusaba A, Arai T. Shiitake mushroom powder supplementation increases antioxidative activity in dogs. Front Vet Sci. 2024;11:1355560. doi:10.3389/fvets.2024.1355560 Cho HW, Choi S, Seo K, Kim KH, Jeon JH, Kim CH, Lim S, Jeong S, Chun JL. Gut microbiota profiling in aged dogs after feeding pet food contained Hericium erinaceus. J Anim Sci Technol. 2022 Sep;64(5):937-949. Kaur J, Seshadri S, Golla KH, Sampara P. Efficacy and safety of standardized ashwagandha (Withania somnifera) root extract on reducing stress and anxiety in domestic dogs: A randomized controlled trial. J Vet Behav. 2022;51:8–15. Bharani KK, Devarasetti AK, Carey L, Khurana A, Kollipaka R, Hanuman DDV, Chetla VS, Banothu AK. Effects of ashwagandha (Withania somnifera) root extract on aging-related changes in healthy geriatric dogs: A randomized, double-blinded placebo-controlled study. Vet Med Sci. 2024 Sep;10(5):e1556 Sacoor C, Marugg JD, Lima NR, Empadinhas N, Montezinho L. Gut-brain axis impact on canine anxiety disorders: new challenges for behavioral veterinary medicine. Vet Med Int. 2024;2024:2856759. doi:10.1155/2024/2856759 Lee E, Carreras-Gallo N, Lopez L, Turner L, Lin A, Mendez TL, Went H, Tomusiak A, Verdin E, Corley M, Ndhlovu L, Smith R, Dwaraka VB. Exploring the effects of Dasatinib, Quercetin, and Fisetin on DNA methylation clocks: a longitudinal study on senolytic interventions. Aging (Albany NY). 2024;16(4):3088–3106. doi:10.18632/aging.205581 Bitto A, Ito TK, Pineda VV, LeTexier NJ, Huang HZ, Sutlief E, Tung H, Vizzini N, Chen B, Smith K, Meza D, Yajima M, Beyer RP, Kerr KF, Davis DJ, Gillespie CH, Snyder JM, Treuting PM, Kaeberlein M. Transient rapamycin treatment can increase lifespan and healthspan in middle-aged mice. eLife. 2016;5:e16351. doi:10.7554/eLife.16351 Urfer SR, Kaeberlein TL, Mailheau S, Bergman PJ, Creevy KE, Promislow DEL, Kaeberlein M. A randomized controlled trial to establish effects of short-term rapamycin treatment in 24 middle-aged companion dogs. GeroScience. 2017;39(2):117–127. doi:10.1007/s11357-017-9972-z Kaeberlein M, Creevy KE, Promislow DEL. The Dog Aging Project: translational geroscience in companion animals. Mamm Genome. 2016;27(7–8):279–288. doi:10.1007/s00335-016-9638- Mulder IE, Schmidt B, Lewis M, Delday M, Stokes CR, Bailey M, Aminov RI, Gill BP, Pluske JR, Mayer CD, Kelly D. Restricting microbial exposure in early life negates the immune benefits associated with gut colonization in environments of high microbial diversity. PLoS One. 2011;6(12):e28279. doi:10.1371/journal.pone.0028279 Hemida M, Vuori KA, Moore R, Anturaniemi J, Hielm-Björkman A. Early life modifiable exposures and their association with owner-reported inflammatory bowel disease symptoms in adult dogs. Front Vet Sci. 2021;8:552350. doi:10.3389/fvets.2021.552350 McMahon JE, Graves JL, Tovar AP, Peloquin M, Greenwood K, Chen FL, Nelson M, McCandless EE, Halioua-Haubold CL, Juarez-Salinas D. Translational immune and metabolic markers of aging in dogs. Sci Rep. 2025;15:14460. doi:10.1038/s41598-025-51976-3 Urfer SR, Kaeberlein M. Desexing dogs: a review of the current literature. Animals (Basel). 2019;9(12):1086. doi:10.3390/ani9121086 Santos JDP, Cunha E, Nunes T, Tavares L, Oliveira M. Relation between periodontal disease and systemic diseases in dogs. Res Vet Sci. 2019;125:136–140. doi:10.1016/j.rvsc.2019.05.011 Selting KA, Ringold R, Husbands B, Pithua PO. Thymidine kinase type 1 and C-reactive protein concentrations in dogs with spontaneously occurring cancer. J Vet Intern Med. 2016;30(4):1159–1166. doi:10.1111/jvim.13954 Urfer SR, Kaeberlein M. Desexing dogs: a review of the current literature. Animals (Basel). 2019;9(12):1086. doi:10.3390/ani9121086 Clark JD, Rager DR, Crowell-Davis S, Evans DL. Housing and exercise of dogs: effects on behaviour, immune function and cortisol concentration. Lab Anim Sci. 1997;47(5):500–510 See omnystudio.com/listener for privacy information.

As consumer wearables track everything from our heartbeats to nightly sleep cycles, a new industry has emerged—one focused on making sense of this avalanche of personal health data. In an era when prevention is prized over cure, questions abound: How accurate is the data captured on our wrists and fingers? Can these metrics truly guide us to longer, healthier lives, or are we just generating noise? For Marco Benitez, a biomedical engineer and co-founder of the health data platform Rook, the challenge isn't just about collecting the numbers but turning them into actionable insights—for both individuals and the broader healthcare world. As the medical establishment wrestles with integrating this torrent of information—and as users grapple with privacy and security—a revolution in health is quietly unfolding. Peter Bowes sat down with Benitez to discuss the promise and pitfalls of wearable data, the evolving relationship between Big Pharma and digital health, and what it will take to shift the system from sick care to prevention.___If you value our video and audio content, we would appreciate your support.Any contribution - large or small - is hugely appreciated and helps us to continue sharing insights that could help us all live longer and healthier lives. With gratitude. https://www.buzzsprout.com/87724/support PartiQlar supplementsEnhance your wellness journey with PartiQlar supplements. No magic formulas, just pure single ingredients, like NMN, L-Glutathione, Spermidine, Resveratrol, TMG and Quercetin. Get a 15% discount with the code MASTERAGING15 at PartiQlarSupport the showThe Live Long and Master Aging (LLAMA) podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice. If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.

Dr Steve, Dr Scott, and Lady Diagnosis discuss: What are Quercetin and Zinc used for? Can you use vascepa prophylactically? Quinine pills for leg cramps? Why was it banned by the FDA? A challenging hip pain and more Please visit: ⁠⁠⁠⁠simplyherbals.net/cbd-sinus-rinse⁠⁠⁠⁠ (the best he's ever made. Seriously.) ⁠⁠⁠⁠instagram.com/weirdmedicine⁠⁠⁠⁠ ⁠⁠⁠⁠x.com/weirdmedicine⁠⁠⁠⁠ ⁠⁠⁠⁠stuff.doctorsteve.com⁠⁠⁠⁠ (it's back!) ⁠⁠⁠⁠youtube.com/@weirdmedicine ⁠⁠⁠⁠(click JOIN and ACCEPT GIFTED MEMBERSHIPS. Join the "Fluid Family" for live recordings!) ⁠⁠⁠⁠youtube.com/@normalworld ⁠⁠⁠⁠(Check out Dave and crew, and occasionally see your old pal!) supertip.gg/drsteve (make your pals say awful things through the magic of AI) CHECK OUT THE ROADIE COACH stringed instrument trainer! ⁠⁠⁠⁠roadie.doctorsteve.com⁠⁠⁠⁠ (the greatest gift for a guitarist or bassist! The robotic tuner!) see it here: ⁠⁠⁠⁠stuff.doctorsteve.com/#roadie⁠⁠⁠⁠ Also don't forget: ⁠⁠⁠⁠Cameo.com/weirdmedicine⁠⁠⁠⁠ (Book your old pal right now because he's cheap! "FLUID!") Most importantly! ⁠⁠⁠⁠CHECK US OUT ON PATREON! ⁠⁠⁠⁠ ALL NEW CONTENT! Robert Kelly, Mark Normand, Jim Norton, Gregg Hughes, Anthony Cumia, Joe DeRosa, Pete Davidson, Geno Bisconte, Cassie Black ("Safe Slut"). Stuff you will never hear on the main show ;-) Learn more about your ad choices. Visit podcastchoices.com/adchoices

Future nutrition should be personalized, with artificial intelligence as a key driver, according to Melissa Snover, founder of Nourished, a UK-based company that makes 3D-printed gummy vitamin and supplement stacks.  She believes the current approach to supplementation and health products is outdated and poorly tailored to individual needs. Snover, registered dietitian, joined us to discuss the burgeoning field of precision nutrition. Nourished uses AI-powered algorithms to create customized nutrient gummies, based on users' lifestyle data and health goals—an approach she says offers a significant leap beyond the traditional "one size fits all" vitamin regime.  PartiQlar supplementsEnhance your wellness journey with PartiQlar supplements. No magic formulas, just pure single ingredients, like NMN, L-Glutathione, Spermidine, Resveratrol, TMG and Quercetin. Get a 15% discount with the code MASTERAGING15 at PartiQlarSupport the showThe Live Long and Master Aging (LLAMA) podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice. If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.

In this encore episode, we highlight the role of vitamin B1 (thiamine) in supporting gastrointestinal function, focusing on intestinal motility while detailing vitamin B1's involvement in acetyl-CoA and acetylcholine synthesis. We discuss thiamine insufficiency as well as how small intestinal bacterial overgrowth (SIBO) may further affect thiamine availability. We further detail host defense mechanisms—including gastric acid, pancreatic enzymes, and gastrointestinal motility—that work in concert to regulate microbial balance in the small intestine. Topics: 1. Introduction- Focus on SIBO, intestinal motility, and vitamin B1 (thiamine)  2. Small Intestine and Microbial Regulation- Low bacterial load under healthy conditions  - Protective mechanisms: gastric acid, enzymes, motility…   3. Overview of SIBO Subtypes - H₂-SIBO, hydrogen-producing bacteria  - IMO, methane-producing archaea  - H₂S-SIBO, hydrogen sulfide-producing bacteria  - Subtypes can coexist, share underlying factors   4. Host Factors in Microbial Regulation - Gastric acid, motility, pancreatic enzymes, bile acids, and immune surveillance  5. Gastric Acid and Parietal Cells  - Hydrochloric acid and intrinsic factor  - Acid environment supports digestion and microbial regulation  - Protein denaturation and pepsin activation 6. Chief Cells and Enzyme Function - Pepsinogen and gastric lipase  - Pepsinogen activated by acidic pH   7. Hypochlorhydria and Downstream Effects 8. Pancreatic Enzymes in the Small Intestine   9. Intestinal Motility and the Enteric Nervous System (ENS)- Coordinated smooth muscle contractions  - Myenteric and submucosal plexuses   10. Intestinal Wall Anatomy - Epithelium and lamina propria - Submucosa contains the submucosal plexus  - Myenteric plexus located between muscle layers   11. Vitamin B1 (Thiamine) and Gastrointestinal Function  - Acetylcholine synthesized from choline and acetyl-CoA  - Acetyl-CoA formation, thiamine availability  - Acetylcholine signaling  12. SIBO and Nutrient Availability- Bacterial overgrowth can affect nutrient absorption  - Thiaminases   13. Conclusion  - Root cause approach, multi-factorial Thank you to our episode sponsor: 1. ⁠⁠OmneDiem®'s⁠⁠ ⁠⁠Histamine Digest®⁠⁠ and ⁠⁠Histamine Digest® PureMAX⁠⁠ 2. ⁠⁠Histamine Digest® Histamine Complete⁠⁠ with DAO, Vitamin C, Quercetin, Bromelain, and Stinging Nettle Root Extract.Thanks for tuning in!Get Chloe's Book Today! "⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠75 Gut-Healing Strategies & Biohacks⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠" Follow Chloe on Instagram ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@synthesisofwellness⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Follow Chloe on TikTok @chloe_c_porterVisit ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠synthesisofwellness.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ to purchase products, subscribe to our mailing list, and more!

In this episode, we detail connections between H. pylori and hypochlorhydria, while highlighting possible downstream effects on nutrient absorption. We examine how reduced gastric acidity can impair the liberation and assimilation of certain micronutrients, including iron, calcium, vitamin B12, and more; and we further discuss the impact of low stomach acid upon downstream digestive enzyme activation and gut microbial balance. The discussion also highlights the role of compromised gastric acidity in conditions such as small intestinal bacterial overgrowth (SIBO).Topics:1. Hypochlorhydria - Low stomach acid.- Aging, autoimmune gastritis, chronic PPI use, H. pylori infection.2. H. pylori - Common gram-negative bacterium that colonizes the stomach lining.- Symptoms.- Produces urease.- Ammonia neutralizes acid, creating a protective microenvironment.- Additional virulence factors and ability to form biofilms contribute to persistence.3. Gastric Anatomy & Layers- The stomach: hollow, muscular organ for mechanical and chemical digestion.- Regions: Cardia, fundus, body, and pylorus.- Layers: Mucosa, Submucosa, Muscularis externa, Serosa4. Mucosal Layer - Surface mucous cells secrete a thick bicarbonate-rich, protective mucus.- Gastric pits lead to gastric glands, which contain specialized secretory cells.5. Specialized Gastric Cells- Parietal Cells: Secrete hydrochloric acid (HCl) and intrinsic factor (IF).- Chief Cells: Secrete pepsinogen (converted to pepsin by HCl) and gastric lipase.- Role of HCl: Activates pepsin, denatures proteins, and contributes to nutrient absorption.- Intrinsic factor and vitamin B12 absorption.6. Vitamin B12 Absorption- Essential for DNA synthesis, RBC formation, neurological function.- Released from food proteins by gastric acid and pepsin.- Impaired absorption.7. Role of Gastric Acid in Broader Micronutrient Absorption- Absorption of minerals.- Soluble, ionized state.- Iron: HCl aids in preventing insoluble precipitates and supports iron absorption.8. Protective Role of Gastric Acid- Acts as a line of defense against ingested pathogens.- Maintains low microbial diversity in the stomach.- Low HCl and SIBO (Small Intestinal Bacterial Overgrowth).9. Symptoms of Low Stomach Acid- Bloating, early satiety, excessive belching.- Undigested food in stool, chronic constipation.- May reflect impaired enzymatic activation and digestive insufficiency.10. Conclusion- Multifactorial causes and downstream effects.- Optimal range of stomach acid: neither high nor low.Thank you to our episode sponsor: 1. ⁠OmneDiem®'s⁠ ⁠Histamine Digest®⁠ and ⁠Histamine Digest® PureMAX⁠ 2. ⁠Histamine Digest® Histamine Complete⁠ with DAO, Vitamin C, Quercetin, Bromelain, and Stinging Nettle Root Extract.Thanks for tuning in!Get Chloe's Book Today! "⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠75 Gut-Healing Strategies & Biohacks⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠" Follow Chloe on Instagram ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@synthesisofwellness⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Follow Chloe on TikTok @chloe_c_porterVisit ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠synthesisofwellness.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ to purchase products, subscribe to our mailing list, and more!

Today, I'm welcoming back Dr. Jeffrey Gross, a true pioneer in the regenerative longevity space. You might remember our earlier episode where we explored the transformative science of human exosomes—but today, we're going even further, straight into the fascinating world of plant exosomes.   What we discuss: Plant exosomes intro ... 00:04:23 Gut health/minerals ... 00:05:18 Why plant exosomes ... 00:08:09 Exosomes vs. liposomes ... 00:09:35 Bioavailability ... 00:12:12 Phytonutrients ... 00:17:26 Resveratrol ... 00:18:17 Quercetin ... 00:20:30 Glutathione ... 00:22:01 Antioxidant enzymes ... 00:24:02 Fruit yield per cap ... 00:25:32 Melatonin ... 00:26:55 Oral bioavailability ... 00:29:29 Research summary ... 00:30:10 Sirtuin 1/ROS ... 00:31:29 Prepping for joint regen ... 00:42:05 Cartilage success ... 00:44:00 European edge ... 00:47:48 B vitamins ... 00:48:25 Microbiome ... 00:51:50 Fisetin/dosing ... 00:53:22   Our Amazing Sponsors: Mimio - A supplement that gives you all the cellular, metabolic, and longevity benefits of a prolonged fast—even on the days when you're eating normally. Visit mimiohealth.com/nat and use code NAT FOR 20% off your first single purchase or subscription order. BEAM Minerals - are one of the most overlooked contributors to a healthy gut. They help feed and support your microbiome. Research shows that good gut bacteria rely on essential minerals like calcium, magnesium, zinc, iron, and phosphorus to thrive.. Head over to www.beamminerals.com and use code NAT20 for 20% off your first order and give your gut the simple support it deserves! Bio-Shield by Young Goose - It's a broad-spectrum serum that protects against UVA/UVB, infrared, AND high-energy visible (HEV) light—aka the stuff pouring out of your laptop right now. Visit YoungGoose.com—use code NAT10 to get started, or 5NAT if you're an existing customer.   More from Nat:  YouTube Channel Join My Membership Community Sign up for My Newsletter  Instagram  Facebook Group

While most people regularly check their blood pressure or glucose, few consider routinely assessing their body's ability to move—and yet, this may be just as crucial to long-term health. Andrew Menter, CEO of Physmodo, joined Peter Bowes to explore the software company's mission to raise the profile of movement as a vital sign of good health. Andrew shares his personal journey from a career in law and finance to entrepreneurship in movement science, motivated in part by his athletic pursuits and the injuries that accompanied them. He discusses Physmodo's innovative use of computer vision technology, enabling self-assessment of mobility and posture via simple smartphone or tablet tools—making this once-specialized information accessible to everyone, not just elite athletes. He highlights the power of early intervention, the surprising ways movement influences sleep and mental health, and the growing importance of personalized preventive care.  PartiQlar supplementsEnhance your wellness journey with PartiQlar supplements. No magic formulas, just pure single ingredients, like NMN, L-Glutathione, Spermidine, Resveratrol, TMG and Quercetin. Get a 15% discount with the code MASTERAGING15 at PartiQlarSupport the showThe Live Long and Master Aging (LLAMA) podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice. If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.

In this episode, we detail Small Intestinal Fungal Overgrowth (SIFO), with a focus on fungal biofilm formation and its role in promoting microbial persistence and evasion of host immune responses. We discuss the phenotypic plasticity of Candida species, as well as biofilm matrices adherent to the intestinal mucosa. We further highlight common symptoms of SIFO as well as the effects of hypochlorhydria, reduced pancreatic enzyme and bile output, impaired motility, diminished commensal bacterial populations, and weakened mucosal immunity.Topics: 1. Introduction- Focus on the gut mucosal barrier.- Emphasis on Small Intestinal Fungal Overgrowth (SIFO) and biofilms.2. Intestinal Barrier Anatomy- The mucosa: epithelium, lamina propria, and a thin band of smooth muscle.- The epithelial layer.- Covered by protective mucus composed of mucin glycoproteins secreted by goblet cells.- In the small intestine: less dense mucus.3. Epithelial Integrity- Tight junctions.- Paracellular barrier preventing uncontrolled antigen passage.4. Lamina Propria5. Overview of Small Intestinal Fungal Overgrowth (SIFO)- SIFO involves fungal overgrowth in the small intestine, commonly Candida species.- Small intestines: Low microbial density due to motility, gastric acid, bile acids, immune surveillance, and more.- Contributing factors: hypochlorhydria, impaired motility, reduced digestive enzymes, diminished competitive flora, lowered immunity, and more.6. Candida Pathogenicity- Candida exhibits phenotypic plasticity: yeast and hyphal forms.- Biofilm formation.7. Biofilm Formation- Biofilms are structured communities of microbes within a self-produced extracellular matrix.- Resistance to antimicrobials and immune defenses.- Can develop on intestinal mucosa and in various other regions.8. SIFO and SIBO Overlap- Root causes and overlap between SIFO and Small Intestinal Bacterial Overgrowth (SIBO).- Common symptoms.9. Gastric Acid in More Detail- Stomach epithelium includes mucous, parietal, chief, and enteroendocrine cells- Parietal cells secrete hydrochloric acid.- HCl denatures proteins and aids in inhibiting pathogens.- Hypochlorhydria: possible causes. 10. Downstream Effects of Low Acid11. Gut Motility in More Detail- Motility involves rhythmic smooth muscle contractions.- Enteric nervous system (ENS): myenteric and submucosal plexuses.- Dysautonomia and motility.12. SIFO Contributing Factors13. Candida Regulation- Candida generally remains in unicellular yeast form under homeostatic regulation.- Controlled by microbial competition, host defenses, antifungal peptides, and more.14. Role of Mucus and sIgA- Mucosal immunity (including sIgA) aids in regulating Candida populations.- Low sIgA levels (due to stress, immune suppression, dysbiosis,…) weaken defense 15. Conclusion- Mucosal barrier structure.- SIFO and Candida.- Biofilm formation, microbial persistence, and mucosal disruption.- SIFO and SIBO.- Multifactorial nature of fungal dysbiosis, types of biofilms, and small intestinal overgrowth.Thank you to our episode sponsor: 1. OmneDiem®'s Histamine Digest® and Histamine Digest® PureMAX 2. Histamine Digest® Histamine Complete with DAO, Vitamin C, Quercetin, Bromelain, and Stinging Nettle Root Extract.Thanks for tuning in!Get Chloe's Book Today! "⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠75 Gut-Healing Strategies & Biohacks⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠" Follow Chloe on Instagram ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@synthesisofwellness⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Follow Chloe on TikTok @chloe_c_porterVisit ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠synthesisofwellness.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ to purchase products, subscribe to our mailing list, and more!

Today I'm happy to chat with our patient Leslie who shares her successful journey with histamine intolerance healing. We'll go through how SIBO led to her histamine issues, the connection to low vagus nerve tone, as well as the low histamine diet and treatments such as dao enzymes. Tune in to learn how you can reduce histamine in the body naturally.    Start healing with us! Learn more about our virtual clinic:  https://drruscio.com/virtual-clinic/ Histamine Intolerance and Diet Guide: https://drruscio.com/guides/get-histamine-intolerance-guide/  

Nutritionist Leyla Muedin explores the significance of detoxification and its impact on overall health. She highlights the role of the liver in detoxification and discusses how various foods and nutrients can support liver function to optimize detoxification pathways. Leyla covers the importance of consuming organic produce, clean seafood, and minimizing exposure to toxins found in household products, medications, and certain foods. She also details the phase one and phase two enzymes involved in detoxification, the importance of specific vitamins, minerals, and amino acids, and the signals that might indicate the need for liver support. Lastly, she encourages listeners to make healthier dietary choices and lifestyle changes to support their liver and overall well-being.

Onion juice is a natural hair loss remedy for many different types of hair loss. Whether autoimmune, nutritional, or fungal, onion juice can help stop hair loss naturally and stimulate natural hair growth quickly. Onions are loaded with sulfur, an essential building block for keratin, the protein that builds your hair. Onions have a high amount of quercetin, which is beneficial for autoimmune hair loss cases caused by alopecia. Quercetin helps increase the growth hormones of the hair follicle. It's also a powerful antimicrobial, so it can help protect the scalp against the overgrowth of yeast, fungus, and mold. To use onion juice for hair growth, chop one red onion and blend it in a blender. Put the blended onion through a cheesecloth to separate the liquid from the pulp. Massage the liquid into your scalp for a few minutes in the shower. Don't rinse! Allow the onion juice to sit in your hair for 30 minutes to 1 hour.Rinse your hair and shampoo twice to remove onion odor. Do this twice per week for 4 to 6 weeks. You should notice hair growth after week 3 or 4!To increase the benefits of onion juice for hair, add 5 drops of rosemary oil. In a 2015 randomized trial, rosemary oil was found to be as effective as one of the top medications for alopecia. Rosemary oil has several anti-inflammatory and antioxidant phytonutrients that increase blood flow to the scalp.While onion juice for hair has been proven effective, fermenting it can increase its effectiveness! To do this, combine onion juice, 8 ounces of water, a teaspoon of sea salt, and a ½ teaspoon of raw honey in a glass or mason jar.Cover the mixture with a cheesecloth and allow it to ferment at room temperature for 72 hours. This enhances the quercetin in the onion juice, increasing hair growth. Put the mixture through a cheesecloth to separate the liquid.If you're experiencing hair loss, taking 10,000 to 20,000 IU of vitamin D daily is very beneficial. A healthy diet is also imperative!Dr. Eric Berg DC Bio:Dr. Berg, age 60, is a chiropractor who specializes in Healthy Ketosis & Intermittent Fasting. He is the author of the best-selling book The Healthy Keto Plan, and is the Director of Dr. Berg Nutritionals. He no longer practices, but focuses on health education through social media.

Abbie Smith-Ryan PhD, an expert in exercise and nutritional strategies for women's health, especially during perimenopause, menopause and obesity, discusses evidence-based methods to accelerate fat loss, increase muscle mass, and improve well-being and longevity for women. Topics include accurate body composition measurement, the role of protein and fibre, optimizing pre- and post-exercise fueling, metabolic adaptation, and supplements like Omega-3s, vitamin D, magnesium, and creatine. Dr. Smith-Ryan also stresses consistent, varied exercise routines and mental and physical recovery.Episode Overview (timestamps are approximate):(0:00) Intro/Teaser(11:00) Nutrition for Body Recomposition(22:00) Nutrient Timing Pre and Post Exercise(32:00) Protein Intake for Women(43:00) The Benefits of Inefficiencies(48:00) Optimal Exercise Frequency and Variety(56:00) Key Supplements for Women's Health(1:05:00) Optimizing Perimenopause Nutrition & Recovery(1:12:00) The “After Party” with Dr. StephanieResources mentioned in this episode can be found at https://drstephanieestima.com/podcasts/ep418/A huge thanks to our sponsors:TIMELINE - Improve energy at the cellular level with Mitopure. Save 10% at https://timelinenutrition.com/better with code BETTER.ONESKIN  - Use the power of peptides for firmer, glowing skin. Save 15% at https://oneskin.co/better with code BETTER.LVLUP - Midlife hormonal changes can wreak havoc on your gut health. Ultimate GI Repair combines powerful gut-healing peptides BPC-157, Larazotide Acetate and KPV with gut-nourishing naturals like Zinc L-Caronsine, EMIQ, Quercetin and Tributyrin to soothe your changing digestion. To learn more, visit https://lvluphealth.com/DRSTEPHANIE and use code DRSTEPHANIE for 15% off.BODYBIO - Support your health with Fish Oil Plus. Great straight or in smoothies! Use code BETTER at https://bodybio.com/better for 15% off.

An episode from The Holistic Navigator. This is not to diagnosis or treat any disease/illness. Consult your physician before taking supplements or medications OR before you stop taking medications. This is for entertainment/informational purposes only! Quercetin is a funny sounding nutrient that isn't joking around. It's an antioxidant that's found in plants that is most often associated with sinus and allergy support, but it's a powerhouse that should be considered as a daily supplement. From athletes, allergy sufferers, or anyone exposed to respiratory stressors, quercetin is a wonderful supplement with a plethora of benefits. Meet John Mills: On this week's episode we speak with John Mills, Director of Quality and Compliance at Highland Laboratories in Mt. Angel, Oregon. John walks us through an overview of the general benefits and then looks at a specific quercetin formulation from Mt. Angel Vitamins that includes Zinc, Bromelain, Stinging Nettles, Vitamin-C and Vitamin-D3. He gives us great information about dosing, when and how to take it, and how it should be in everyone's cabinet and part of a daily routine! Some Questions We Discuss: What is quercetin and what are the benefits of it? (5:14) Who might benefit from taking quercetin daily? (8:43) What makes quercetin different from other histamine blockers? (11:55) Can you take too much quercetin?(13:35) Are there any medications that quercetin negatively interacts with? (18:43) Some Key Takeaways From This Episode: Quercetin has surprising benefits for athletes due to its antioxidant effects. (6:16) People with allergies, seasonal or in general, can benefit greatly from quercetin. (8:55) We are overwhelmed with environmental stressors that hurt our lungs so we need to support them. (10:03) Everyone needs to be taking zinc supplements. (14:32) Increase Vitamin C levels when taking quercetin. (18:55) Quercetin may be better suited as a preventative as opposed to a response. (24:18)

In this solo episode of The Red Light Report, Dr. Mike explores the profound connection between mitochondrial health and oral disease. He reviews three recent studies highlighting how red light therapy, methylene blue, and compounds like urolithin A can support oral tissues, reduce inflammation, and even impact systemic conditions like diabetes and neurodegeneration. From root canal innovations to mitophagy in periodontitis, this episode is full of cutting-edge insights and practical applications for anyone interested in longevity, biohacking, or oral health optimization.Key Topics Covered:Study #1: Methylene Blue + Graphene Oxide for Root Canal Photodynamic Therapy• Combining methylene blue and reduced graphene oxide with red light therapy significantly improves antibacterial and antifungal effects in root canals.• Highlights the synergy between methylene blue and red light.• Dr. Mike shares how his nighttime routine—using BioBlue Calm and a red-light toothbrush—may create a low-level photodynamic therapy effect in the mouth.Study #2: Mitophagy in Periodontal Disease• Mitophagy (mitochondrial autophagy) plays a key role in managing inflammation, bone remodeling, and cell death in gum disease.• Key interventions to enhance oral mitophagy:• Urolithin A (strong Pink1/Parkin pathway activator)• Resveratrol, Melatonin (support mitochondrial quality)• Berberine, Curcumin, Metformin (via AMPK activation)• NR, Quercetin (via SIRT1 + PGC-1α pathway)Study #3: Mitochondrial Dysfunction Links Oral and Systemic Diseases• Periodontitis driven by mitochondrial dysfunction is linked to diseases like diabetes, cardiovascular disease, and neurodegeneration.• Key issues:• Impaired mitochondrial fusion/fission, biogenesis, and mitophagy.• Excessive ROS and mitochondrial DNA leakage fuel inflammation.• Poor mitochondrial function impairs periodontal stem cell regeneration.• Therapeutic approaches:• Antioxidants (CoQ10, resveratrol, melatonin, curcumin, EGCG)• Photodynamic therapy (methylene blue + red light)• Mitochondria-targeted compounds to modulate apoptosis and inflammation.Dr. Mike's Takeaways• Oral mitochondrial health is foundational—not isolated from systemic health.• Red light therapy and methylene blue offer powerful synergistic effects, even in oral applications.• A mitochondria-first approach may provide long-term protection against oral and systemic disease.   If you found the information in today's episode particularly interesting and/or compelling, please share it with a family member, friend, colleague and/or anyone that you think could benefit and be illuminated by this knowledge. Sharing is caring :)As always, light up your health! - Key points: 00:00 – Introduction: Mitochondrial Health & Podcast Focus 00:32 – Announcements: Health Alchemy Bundle & Upcoming Events 06:18 – Study 1: Methylene Blue & Red Light Therapy for Root Canal Treatment 08:42 – Methylene Blue Benefits Recap 13:37 – Study 1 Discussion: Photodynamic Therapy Enhancements 16:57 – Practical Application: Methylene Blue for Oral Health 19:40 – Study 2: Mitophagy in Periodontal Disease 23:46 – Targeted Mechanisms to Enhance Mitophagy 28:42 – Study 3: Mitochondrial Dysfunction in Periodontitis & Systemic Diseases 31:38 – Therapeutic Strategies for Mitochondrial Health 41:44 – Integrative Mitochondrial Therapies 47:02 – Conclusion: Mitochondrial Dysfunction as a Core Issue 50:45 – Closing Thoughts & Upcoming Events - Articles referenced in episode:Synthesis, characterization, and application of methylene blue functionalized reduced graphene oxide for photodynamic therapy in root canal treatmentMitophagy and Its Significance in Periodontal DiseaseMitochondrial Dysfunction in Periodontitis and Associated Systemic Diseases: Implications for Pathomechanisms and Therapeutic Strategies - Get over $6,000 worth of wellness education from top experts for $50! The Health Alchemy BundleThis is an amazing opportunity put together by Carrie Bennett and Sarah Kleiner! This Bundle is collection of 60+ eBooks, courses, and other resources available for $50 at a mind-blowing 99% discount.     This massive collection of resources is rooted in the science + spirituality of healing with nature, which cover topics like: Circadian & quantum biology Mental, emotional, & spiritual health Nutrition, minerals, & supplementation (when necessary) Herbalism & homeopathy Movement, posture, & fitness Hormonal health, pregnancy, & parenting And even specific issue support—from healing autoimmunity to improving sleep, & more This is a limited opportunity that goes through TOMORROW, May 23rd, so act now and don't miss out!   Get The Health Alchemy Bundle by clicking here! - Upcoming BioLight Events:   Biohacking Conference - May 28 - 30 (Austin, TX)   Returning to Nature (Quantum Health Retreat), June 26 - 27 (Franklin, TN) - Introducing the Newest BioBlue Supplement! The most comprehensive, powerful mitochondrial support supplement on the market ...   What is The Fountain of Youth in simple terms? An unparalleled supplement for brain power, energy, and longevity This supplement is like a high-performance tune-up for your brain and body. It combines powerful natural and science-backed ingredients to help you think clearer, feel more energized, and support your long-term health.The BioBundle automatically saves you 15% on both of the supplements you choose.   For the next two weeks, SAVE 20% on your order of BioBlue Fountain of Youth! Simply use code FOY20 Code expires 5/29, midnight PST   Click here to check out BioBlue Fountain of Youth - Dr. Mike's #1 recommendations: Water products: Water & Wellness Grounding products: Earthing.com EMF-mitigating products: Somavedic Blue light-blocking glasses: Ra Optics - Stay up-to-date on social media: Dr. Mike Belkowski: Instagram LinkedIn   BioLight: Website Instagram YouTube Facebook

Welcome back to our weekend Cabral HouseCall shows! This is where we answer our community's wellness, weight loss, and anti-aging questions to help people get back on track! Check out today's questions:    Felicia: Hello Dr. Cabral. What are your thoughts on this magnesium supplement ? Magnesium bisglycinate, fillers (microcrystalline cellulose, dicalcium phosphate), anti-caking agents (silicon dioxide, magnesium stearate), coating agents (hydroxypropyl methylcellulose, glycerol). Worth taken or should I look for another one? Thanks for your help                              Audrey: Hi Dr. Cabral, Thank you for being my go to person for all of my health questions! What are your thoughts on taking creatine while pregnant? I am going to keep strength training throughout my pregnancy and am hoping this helps with maintaining some muscle. I've read great things about it helping mom and baby but want to know what you think. I know you cannot give medical advice. Thanks                                                                                                                               Elsa: Hi Dr. Cabral! Thanks for all the information you provide. I'm a fairly recent listener but already have learned so much from you. May God continue to bless you, your family, and your team. My question is regarding my husband. He did a genetic test and came out positive for the MTHFR heterozygous A1298C and COMT heterozygous G472A (Val108/158Met). I've listened to your recent podcasts on COMT, but my question is regarding supplements to avoid if you have this variant. He doesn't take any medications, and already takes methylated B complex to support MTHFR and high homocysteine levels (8.3). He also takes Vit C, Zinc+Copper, Mag, Vit D+K2, Omega 3s, Probiotics. The test results indicate to avoid Quercetin and Green Tea because they are COMT inhibitors? True? Thanks.                                        Bettina: Hello Dr. Cabral. What are your thought on Super CitriMax for weightloss using a combination of 4500 mg Garcinia Cambogia with 60% HCA with 600 mg of Chromium and 1000 mg of B3 Niacinamide or B3 Nicotinamide? Thanks for your thoughts on this.                                                                                             Hannah: Hi Dr Cabral! I wrote in when you said the que was closer to 2-3 weeks and I haven't heard my question yet so this is incase my question got lost- myself and a couple of people I've met recently get an elevated heart rate when drinking alcohol (even 1 drink). This has never happened to me before and I'm very well hydrating prior, what else besides histamines could this be? Second, I have a very scant amount of blood per rectum every couple of days since starting the CBO, have you heard of this happening? I'm thinking to d/c citricidal early, I didn't test prior to CBO and only have 3 days left of that to see if it's related. Thanks for everything!!                           Thank you for tuning into today's Cabral HouseCall and be sure to check back tomorrow where we answer more of our community's questions!    - - - Show Notes and Resources: StephenCabral.com/3389 - - - Get a FREE Copy of Dr. Cabral's Book: The Rain Barrel Effect - - - Join the Community & Get Your Questions Answered: CabralSupportGroup.com - - - Dr. Cabral's Most Popular At-Home Lab Tests: > Complete Minerals & Metals Test (Test for mineral imbalances & heavy metal toxicity) - - - > Complete Candida, Metabolic & Vitamins Test (Test for 75 biomarkers including yeast & bacterial gut overgrowth, as well as vitamin levels) - - - > Complete Stress, Mood & Metabolism Test (Discover your complete thyroid, adrenal, hormone, vitamin D & insulin levels) - - - > Complete Food Sensitivity Test (Find out your hidden food sensitivities) - - - > Complete Omega-3 & Inflammation Test (Discover your levels of inflammation related to your omega-6 to omega-3 levels) - - - Get Your Question Answered On An Upcoming HouseCall: StephenCabral.com/askcabral - - - Would You Take 30 Seconds To Rate & Review The Cabral Concept? The best way to help me spread our mission of true natural health is to pass on the good word, and I read and appreciate every review!  

Cutting-edge medical advances are unlocking new ways to slow aging and enhance health. Plasmapheresis removes harmful inflammatory molecules, toxins, and cellular waste from plasma, helping to reduce biological aging and improve resilience. Muse cells, a powerful form of stem cell therapy, show promise in regenerating tissue and treating complex conditions like ALS and stroke. And peptides—small, naturally occurring signaling molecules—support healing, immune balance, and cellular repair, offering practical tools for longevity and optimized health. In this episode, I talk with Dr. Darshan Shah, Dr. Adeel Khan, and Dr. Edwin Lee about medical advancements that are the ultimate longevity biohacks. Dr. Darshan Shah is a board-certified surgeon, longevity medicine expert, author, and founder of Next Health—the world's largest Health Optimization and Longevity clinic. He has performed over 20,000 surgical procedures and advised thousands on extending healthspan and lifespan. A prodigy in medicine, Dr. Shah earned his MD at 21 and trained at the Mayo Clinic. He has since launched multiple health ventures, authored a book, and patented medical devices. Committed to ongoing learning, he holds alumni status at Harvard Business School and Singularity University. Dr. Shah is a sought-after speaker on health and longevity. Dr. Adeel Khan, M.D. is a cell and gene therapy specialist with a visionary approach that is changing the way we perceive healthcare worldwide. Khan has cemented his reputation as a regenerative medicine expert and a driven entrepreneur. Dr. Edwin Lee is a board-certified endocrinologist, author, and international speaker specializing in hormonal balance, regenerative, and functional medicine. He founded the Institute for Hormonal Balance in Orlando in 2008 and completed fellowships in Critical Care and Endocrinology at the University of Pittsburgh. Dr. Lee is the lead investigator of an IRB-approved senolytic study exploring compounds like Dasatinib, Quercetin, and Fisetin, and recently published the first human trial using BPC157 for knee pain. He is an assistant professor at the University of Central Florida College of Medicine, co-founder of the Clinical Peptide Society, and founder of SavePeptides.org. His latest book is The Fountain of Youth with Peptides. This episode is brought to you by BIOptimizers. Head to bioptimizers.com/hyman and use code HYMAN10 to save 10%. Full-length episodes can be found here: This Breakthrough Blood Therapy Could Add Years To Your LifeStem Cells & Peptides: The Secret to Reversing Chronic Pain and Aging?How Peptides Enhance Healing and Longevity

In this video, Dr. G explores the alarming rise in allergies and offers natural solutions. Dr. G discusses the hygiene hypothesis – how overly clean environments weaken immune systems, leading to increased allergy and autoimmune disease risk. He highlights the dangers of conventional allergy medications and advocates for a holistic approach, emphasizing the importance of early childhood exposure to diverse environments and gut health. The video details five science-backed natural allergy remedies: quercetin, stinging nettle, butterbur, bromelain, and N-acetylcysteine, explaining their mechanisms of action and recommended dosages. #allergies #natural #wellness ==== Thank You To Our Sponsor! Jaspr Go to jaspr.co/DRG and use code DRG for $300 off for a limited time. ==== Timestamps: 00:00:00 - Allergies: Hygiene Hypothesis 05:07 - Immune System & Environment 06:23 - Air Quality & Home Health 09:26 - Quercetin & Nettle for Allergies 12:31 - Natural Allergy Remedies 15:40 - NAC, Allergies & Immunity Be sure to like and subscribe to #HealThySelf Hosted by Doctor Christian Gonzalez N.D. Follow Doctor G on Instagram @doctor.gonzalez https://www.instagram.com/doctor.gonzalez/