Podcasts about Quercetin

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Intelligent Medicine
Q&A with Leyla, Part 2: Ganglion Cyst

Intelligent Medicine

Play Episode Listen Later Aug 28, 2025 34:07


How much leucine should I take to regain muscle?Should I increase my creatine dose to 10 grams daily for the cognitive benefits?You talked about the cancer risk of CT scans. What about CT angiograms?  I've had a ganglion cyst drained twice. How can I keep it from coming back?Who can I contact for treatment of mast cell activation syndrome?I heard you should brush your teeth with fluoride toothpaste if there's no fluoride in your drinking water 

BH Sales Kennel Kelp CTFO Changing The Future Outcome

Grandpa Bill's Brain Fuel: The Top Supplements Dr. Amen Recommends for a Healthier MindGrandpa Bill here. For the past few days, we've been on a mission to improve our brain health. We've talked about a great workout for the mind, but today, we're going to dive into what to feed it. Dr. Daniel Amen, a man who has looked at more brain scans than almost anyone, teaches us that you can't have a healthy mind without the right fuel. So, let's talk about his top supplement suggestions—the brain-boosting heroes you might want to add to your daily routine.Remember, always talk to your doctor before starting any new supplement. They're your co-pilot on this journey.If you think of your brain as a house, Omega-3s (like DHA and EPA) are the high-quality lumber. They are a core component of your brain cell membranes. Dr. Amen considers them foundational for memory, mood, and overall brain structure.This trio of B vitamins works together to create energy in the brain. They also help clear away a substance that can be harmful to our blood vessels, keeping the pathways clear for good blood flow. Think of them as the team that keeps the lights on in your mind, ensuring your brain has the juice to function optimally.Choline is a key nutrient your body uses to create a messenger for memory called acetylcholine. Having enough choline is like having a reliable mail carrier—it helps ensure that your memory messages get delivered quickly and accurately.You might think these are just for your stomach, but your gut is often called your "second brain." The healthy bacteria in your gut send signals to your mind that can help manage stress and anxiety. A happy gut often means a happier brain!Dr. Amen points to mushrooms like Cordyceps and Reishi. These are known as "adaptogens," meaning they help your body and brain handle stress more effectively. They don't create a buzz; they train your brain to be more resilient, like a personal trainer building strength.These are powerful compounds that fight inflammation throughout your body, including your brain. Inflammation can harm brain cells over time, so Curcumin and Quercetin act like a cleanup crew, reducing swelling and protecting your mind from damage.This one is crucial for everyone! Vitamin D is vital for mood and overall brain health. Studies show that a lack of Vitamin D is common and can be tied to feelings of sadness. Getting enough of this "sunshine vitamin" can make a world of difference.Rounding out the list, Saffron is a great mood booster, while Ginkgo Biloba helps promote healthy blood flow to the brain.So, there you have it, folks. By giving your brain the right fuel, you're not just taking supplements; you're building a healthier, happier you from the inside out.Keep that body and mind moving!1. Omega-3s (The Brain's Building Blocks)2. B12, B6 & Folate (The Power Plant)3. Choline (The Memory Messenger)4. Probiotics (The Gut-Brain Connection)5. "Smart Mushrooms" (Resilience Trainers)6. Curcumin & Quercetin (The Cleanup Crew)7. Vitamin D (The Sunshine Vitamin)8. Saffron & Ginkgo Biloba#supplements,#BrainHealth,#BrainSupplements,#DanielAmen,#HolisticHealth,#WorkoutsForGeriatrics,#WorkoutsForGeriatrics#SilverStreakers,#HealthyAging,#CognitiveHealth,#Wellness,#Nootropics,#GrandpaBill,

The Synthesis of Wellness
194. The Oral-Gut Axis | The Oral Microbiome and The Intestinal Microbiome

The Synthesis of Wellness

Play Episode Listen Later Aug 22, 2025 18:29


In this encore episode, we detail the oral-gut microbiota axis, detailing the oral microbiome and its relationship with the intestinal microbiome. We discuss the development of oral biofilm, the transition from plaque to dental calculus, and potential impacts of oral dysbiosis, while highlighting intestinal health and focusing on Fusobacterium nucleatum. Topics:1. Overview of the Oral Microbiome and the Oral-Gut Axis - The oral cavity and the gut: microbially dense sites. - Anatomically distinct but connected and capable of influencing each other. - The oral microbiome. - Microbial distribution: topography and chemistry of oral surfaces. 2. Oral Cavity Anatomy and Microenvironments - The vestibule and oral cavity proper. - Lined by oral mucosa, which varies in structure. - Unique ecological niches that support different microbial populations. 3. Tooth Structure and Relevance to Microbial Colonization - Teeth are embedded in the alveolar processes of the maxilla and mandible. - Tooth structure. - Long-term microbial colonization and biofilm development. 4. Biofilm / Dental Plaque Development - Biofilm begins with the formation of the acquired pellicle.- Pioneer species secreting extracellular polymeric substances (EPS).- Secondary colonizers coaggregate.- Coaggregation is species-specific.- Example.- Aerobes can lower local oxygen levels, creating micro anaerobic niches that support obligate anaerobes. 5. Maturation of the Biofilm  - Biofilm composition shifting to anaerobic, proteolytic species such as P. gingivalis. - F. nucleatum: a bridge species. 6. Mineralization and Formation of Dental Calculus - Mineralization, calcium and phosphate deposition. - Dental calculus. 7. Oral Dysbiosis  - An imbalance in the oral microbial community. - Potential signs and symptoms. - Halitosis, swollen or bleeding gums, tooth sensitivity. 8. Oral-Gut Axis and Systemic Implications - Physical, chemical, biochemical, and immunological barriers aid in preventing oral bacteria from colonizing the gut. - Oral bacteria can potentially impact intestinal health. -  F. nucleatum and IBD. 9. Oral Microbiome Testing10. Multi-Factorial Thank you to our episode sponsors: 1. ⁠⁠⁠⁠⁠OmneDiem®'s⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠Histamine Digest®⁠⁠⁠⁠⁠ and ⁠⁠⁠⁠⁠Histamine Digest® PureMAX⁠⁠⁠⁠⁠ : Use code STXAL9VI for 15% off.2. ⁠⁠⁠⁠⁠Histamine Digest® Histamine Complete⁠⁠⁠⁠⁠ with DAO, Vitamin C, Quercetin, Bromelain, and Stinging Nettle Root Extract: Use code STXAL9VI for 15% off.3. ⁠Codex Labs⁠: Explore Codex Labs' collections for ⁠acne⁠, ⁠eczema⁠, and more. Shop the ⁠BIA Collection HereGet Chloe's Book Today! "⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠75 Gut-Healing Strategies & Biohacks⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠" Follow Chloe on Instagram ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@synthesisofwellness⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Visit ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠synthesisofwellness.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

Intelligent Medicine
Intelligent Medicine Radio for August 16, Part 2: NAC for Parkinson's

Intelligent Medicine

Play Episode Listen Later Aug 18, 2025 44:23


The Synthesis of Wellness
193. The Intestinal Mucosal Barrier & Hyperpermeability | Highlighting the Role of Zinc in Supporting Intestinal Barrier Function

The Synthesis of Wellness

Play Episode Listen Later Aug 15, 2025 15:06


In this episode, we detail the structure and function of the intestinal mucosal barrier, highlighting key roles that zinc plays in supporting various aspects of mucosal barrier integrity. We detail key anatomical features, including the mucus layer, epithelial cells, and tight junctions, before discussing zinc's physiological roles, its relationship with copper, and factors that can affect zinc levels. The discussion further details mechanistic features of zinc absorption as well as specialized forms such as zinc carnosine.Topics:1. Introduction - Overview of intestinal hyperpermeability and intestinal barrier function- Highlighting the role of zinc 2. Intestinal Barrier Anatomy - Four major layers: mucosa, submucosa, muscularis externa, serosa- Mucosa subdivisions; focus on epithelium  3. The Mucus Layer  - Location over the epithelial surface- Composition: mucin-rich, secreted by goblet cells- Goblet cell mucin storage and expansion upon hydration- Functions: trapping pathogens, lubricating epithelium, housing molecules including secretory IgA- Small intestine mucus - Large intestine mucus 4. The Intestinal Epithelium - Monolayer of epithelial cells: enterocytes, goblet cells, and more- Tight junctions, paracellular transport - Continuous epithelial renewal 5. Introduction to Zinc - Zinc as a trace mineral required in minute quantities for numerous physiological processes - Second most abundant trace mineral after iron; majority stored in muscle and bone- Maintaining plasma and intracellular zinc concentrations within narrow range- Both deficiency and excess can disrupt biochemical processes 6. Zinc and Copper  - Zinc and copper as closely interconnected minerals- Zinc, copper, and metallothionein binding in enterocytes- Both high and low zinc can disrupt zinc-copper balance- Metallothionein as a cysteine-rich metal-binding protein  7. Factors Affecting Zinc Levels  - Multifactorial- Possible signs of low zinc status 8. Zinc Absorption  - Dietary sources- Primary absorption in small intestine - In the stomach: HCl and pepsin denature proteins and cleave peptide bonds, releasing zinc from protein complexes- Dietary zinc often bound within tertiary protein structure- Specialized transporters  9. Zinc's Role in the Intestinal Barrier  - Zinc and tight junction proteins- Zinc and Intestinal Epithelial Cells - Zinc and the mucus layer 10. Broader Context of Zinc in Physiology   11. Zinc Carnosine  - Molecular complex of zinc and carnosine- L-carnosine composed of beta-alanine and L-histidine- Gastrointestinal context 12. Conclusion - Multifactorial and multi-system.Thank you to our episode sponsors: 1. ⁠⁠⁠⁠OmneDiem®'s⁠⁠⁠⁠ ⁠⁠⁠⁠Histamine Digest®⁠⁠⁠⁠ and ⁠⁠⁠⁠Histamine Digest® PureMAX⁠⁠⁠⁠ : Use code STXAL9VI for 15% off.2. ⁠⁠⁠⁠Histamine Digest® Histamine Complete⁠⁠⁠⁠ with DAO, Vitamin C, Quercetin, Bromelain, and Stinging Nettle Root Extract: Use code STXAL9VI for 15% off.3. Codex Labs: Explore Codex Labs' collections for acne, eczema, and more. Shop the BIA Collection HereThanks for tuning in!Get Chloe's Book Today! "⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠75 Gut-Healing Strategies & Biohacks⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠" Follow Chloe on Instagram ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@synthesisofwellness⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Visit ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠synthesisofwellness.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

SGT Report's The Propaganda Antidote
RED ALERT: SPIKED! -- Dr. Peter McCullough

SGT Report's The Propaganda Antidote

Play Episode Listen Later Aug 13, 2025 43:11


Protect Your Retirement with a PHYSICAL Gold and/or Silver IRA https://www.sgtreportgold.com/ CALL( 877) 646-5347 - You Can Trust Noble Gold. Dr. Peter McCullough returns to SGT Report to discuss the most harmful product ever devised by man, it's responsible for innumerable injuries and millions of deaths around the world and it's till on the market. In fact, the spike protein may be clotting YOUR blood whether you took this product or not. Join us to learn about the problem AND the fix.   Simplify (& MAXIMIZE) your HSA/FSA account & reimbursements HERE: https://wellnesspay.com/sgt   Get HEALTH CARE from HONEST Doctors at The Wellness Center: https://www.TWC.health/SGT GET the Zinc, Quercetin, Vitamin C & D we all NEED in Z-Stack: www.zstacklife.com/sgtreport Remove MAC codes, heavy metals, graphene oxide & nanotech from your blood w/ MaterPeace: https://masterpeacebyhcs.com/?ref=4094 https://rumble.com/embed/v6vbe7i/?pub=2peuz

Live Long and Master Aging
Step Count Science: Why 7,000 Is the New 10,000 | Melody Ding

Live Long and Master Aging

Play Episode Listen Later Aug 11, 2025 24:23 Transcription Available


A new study is challenging one of the most pervasive messages in health and fitness: the belief that 10,000 daily steps are needed to prolong life and prevent disease. Led by Professor Melody Ding at the University of Sydney and published in The Lancet, the study is the largest of its kind, analyzing data from more than 30 studies worldwide. Its findings suggest that significant health benefits may be achieved with as few as 7,000 steps a day—an attainable target for many who find 10,000 steps daunting. In this interview, Professor Ding discusses the scientific basis for rethinking our daily activity goals, how the research caught global attention, and what it means for public health recommendations moving forward. Peter Bowes speaks to Professor Ding to unpack what this shift in guidance could mean for millions tracking their steps around the world. PartiQlar supplementsEnhance your wellness journey with PartiQlar supplements. No magic formulas, just pure single ingredients, like NMN, L-Glutathione, Spermidine, Resveratrol, TMG and Quercetin. Get a 15% discount with the code MASTERAGING15 at PartiQlarEnergyBits algae snacksA microscopic form of life that could help us age better. Use code LLAMA for a 20 percent discountDisclaimer: This post contains affiliate links. If you make a purchase, I may receive a commission at no extra cost to you.Support the showThe Live Long and Master Aging (LLAMA) podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice. If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.

The Synthesis of Wellness
191. The Gut-Immune Axis | Intestinal Secretory IgA, Lactoferrin, and Lactoferrin Levels

The Synthesis of Wellness

Play Episode Listen Later Aug 8, 2025 14:24


In this encore episode, we detail the gut-immune axis, focusing on the protective mucus layer and the roles of secretory immunoglobulin A and lactoferrin in intestinal health. We discuss endogenous secretions as well as highlight lactoferrin testing and levels. Topics: 1. The Intestinal Barrier & Mucus Layer- The intestinal lumen, microbiome, mucus layer, epithelial cells, and lamina propria.- The mucus layer: antimicrobial peptides (AMPs) and secretory IgA (sIgA).- Intestinal epithelial cells including goblet cells and enterocytes.2. Immune Cells in the Gut- The lamina propria.- Macrophages, dendritic cells, neutrophils, B cells, T cells, mast cells, and more.3. Antimicrobial Peptides & Secretory IgA- AMPs and sIgA in the mucus layer aid in regulating microbial balance and pathogen adhesion.4. Lactoferrin: Functions & Sources- Iron-binding glycoprotein, antimicrobial and immunomodulatory properties.- Found in mucosal secretions, colostrum, and more.- Intestinal epithelial cells (IECs) and neutrophils.5. Lactoferrin's Role in Intestinal Health- Regulates iron absorption via lactoferrin receptors (LFR)on enterocytes.- Sequesters free iron, limiting bacterial growth, bacteriostatic.- Destabilizes bacterial membranes, cell lysis, bactericidal.6. Lactoferrin Levels- Neutrophils release lactoferrin during infection,increasing its presence in the large intestine.- Fecal lactoferrin levels.- Fecal calprotectin levels.7. Candida Overgrowth8. Lactoferrin Supplementation to Support the Gut9. Conclusion- The intestinal mucus layer.- Lactoferrin.Thank you to our episode sponsor: 1. ⁠⁠⁠OmneDiem®'s⁠⁠⁠ ⁠⁠⁠Histamine Digest®⁠⁠⁠ and ⁠⁠⁠Histamine Digest® PureMAX⁠⁠⁠ 2. ⁠⁠⁠Histamine Digest® Histamine Complete⁠⁠⁠ with DAO, Vitamin C, Quercetin, Bromelain, and Stinging Nettle Root Extract.Thanks for tuning in!Get Chloe's Book Today! "⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠75 Gut-Healing Strategies & Biohacks⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠" Follow Chloe on Instagram ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@synthesisofwellness⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Visit ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠synthesisofwellness.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

Pure Animal Podcast
Rethinking healthy ageing in dogs with Dr Matthew Muir

Pure Animal Podcast

Play Episode Listen Later Aug 5, 2025 54:06


In this episode Dr Sarah Howard discusses healthy ageing in dogs with Dr Matthew Muir. Topics discussed include: The reason ageing is currently a hot topic. What leads to an increased lifespan and better quality of life? Diet changes that can impact ageing in dogs. Dr Muir discusses what we should avoid in order to increase lifespan. Matthew goes into details of what dogs' diets should look like to prevent disease. How often should we be feeding our pets? What happens to the gut microbiome as dogs get older? Dr Muir delves into supplements that can be beneficial for ageing and emerging tools that are becoming available. The importance of preventative medicine - proactive vs reactive care. Accelerators of biological ageing. Additional resources: https://pubmed.ncbi.nlm.nih.gov/11991408/ https://pmc.ncbi.nlm.nih.gov/articles/PMC11675035/https://www.frontiersin.org/journals/veterinary-science/articles/10.3389/fvets.2024.1355560/full https://pmc.ncbi.nlm.nih.gov/articles/PMC11505706/ https://www.mdpi.com/1660-3397/18/11/564https://pmc.ncbi.nlm.nih.gov/articles/PMC4936929/ https://pubmed.ncbi.nlm.nih.gov/22216092/ Adams VJ, Watson P, Carmichael S, Gerry S, Penell J, Morgan DM. Exceptional longevity and potential determinants of successful ageing in a cohort of 39 Labrador retrievers: results of a prospective longitudinal study. Acta Vet Scand. 2016;58:29. doi:10.1186/s13028-016-0204-8 Cupp CJ, Jean-Philippe C, Kerr WW, Patil AR. Effect of nutritional interventions on longevity of senior cats. Int J Appl Res Vet Med. 2007;5(3):133–149 Bermingham EN, Patterson KA, Shoveller AK, Fraser K, Butowski CF, Thomas DG. Nutritional needs and health outcomes of ageing cats and dogs: is it time for updated nutrient guidelines? Anim Front. 2024;14(3):5–16. doi:10.1093/af/vfae008 Jackson J, Radford AD, Belshaw Z, Wallis LJ, Kubinyi E, German AJ, Westgarth C. Using veterinary health records at scale to investigate ageing dogs and their common issues in primary care. J Small Anim Pract. 2025;66(2):81–91. doi:10.1111/jsap.13809 Creevy KE, O'Neill DG, Promislow DEL. Morbidity and mortality in elderly dogs – a model for human aging. BMC Vet Res. 2022;18(1):456. doi:10.1186/s12917-022-03518-8 Lewis TW, Wiles BM, Llewellyn-Zaidi AM, Evans KM, O’Neill DG. Longevity and mortality in Kennel Club registered dog breeds in the UK in 2014. Canine Genet Epidemiol. 2018;5:10. doi:10.1186/s40575-018-0066-8 Kealy RD, Lawler DF, Ballam JM, Mantz SL, Biery DN, Greeley EH, Lust G, Segre M, Smith GK, Stowe HD. Effects of diet restriction on life span and age-related changes in dogs. J Am Vet Med Assoc. 2002;220(9):1315–1320. doi:10.2460/javma.2002.220.1315 Guelfi G, Capaccia C, Tedeschi M, Bufalari A, Leonardi L, Cenci-Goga B, Maranesi M. Dog aging: a comprehensive review of molecular, cellular, and physiological processes. Cells. 2024;13(24):2101. doi:10.3390/cells13242101 Laflamme DP. Nutritional care for aging cats and dogs. Vet Clin North Am Small Anim Pract. 2012;42(4):769–791. doi:10.1016/j.cvsm.2012.04.002 Hall JA, Jewell DE. Feeding healthy beagles medium-chain triglycerides, fish oil, and L-carnitine offsets age-related changes in serum fatty acids and carnitine metabolites. PLoS One. 2012;7(11):e49510. doi:10.1371/journal.pone.0049510 Bermingham EN, Patterson KA, Shoveller AK, Fraser K, Butowski CF, Thomas DG. Nutritional needs and health outcomes of ageing cats and dogs: is it time for updated nutrient guidelines? Anim Front. 2024;14(3):5–16. doi:10.1093/af/vfae008 Bray EE, Zheng Z, Tolbert MK, McCoy BM, Kaeberlein M, Kerr KF; Dog Aging Project Consortium. Once-daily feeding is associated with better health in companion dogs: results from the Dog Aging Project. GeroScience. 2022;44(3):1779–1790. doi:10.1007/s11357-022-00575-7 Palaseweenun P, Hagen‐Plantinga EA, Schonewille JT, Koop G, Butre C, Jonathan M, Wierenga PA, Hendriks WH. Urinary excretion of advanced glycation end products in dogs and cats. J Anim Physiol Anim Nutr (Berl). 2021;105(1):149–156. doi:10.1111/jpn.13347 Yang L, Yang L, Cai Y, Luo Y, Wang H, Wang L, Chen J, Liu X, Wu Y, Qin Y, Wu Z, Liu N. Natural mycotoxin contamination in dog food: a review on toxicity and detoxification methods. Ecotoxicol Environ Saf. 2023;257:114948. doi:10.1016/j.ecoenv.2023.114948 Bridglalsingh S, Archer-Hartmann S, Azadi P, Barbier de La Serre C, Remillard RL, Sunvold GD, Bartges JW. Association of four differently processed diets with plasma and urine advanced glycation end products and serum soluble receptor for advanced glycation end products concentration in healthy dogs. J Anim Physiol Anim Nutr (Berl). 2024;108(3):735–751. doi:10.1111/jpn.13927 Marchi PH, Vendramini THA, Perini MP, Zafalon RVA, Amaral AR, Ochamotto VA, Da Silveira JC, Dagli MLZ, Brunetto MA. Obesity, inflammation, and cancer in dogs: review and perspectives. Front Vet Sci. 2022;9:1004122. doi:10.3389/fvets.2022.1004122 Schmid SM, Hoffman JM, Prescott J, Ernst H, Promislow DEL, Creevy KE; Dog Aging Project Consortium. The companion dog as a model for inflammaging: a cross-sectional pilot study. GeroScience. 2024;46(6):5395–5407. doi:10.1007/s11357-024-01217-w Ren J, Li H, Zeng G, Pang B, Wang Q, Wei J. Gut microbiome-mediated mechanisms in aging-related diseases: are probiotics ready for prime time? Front Pharmacol. 2023;14:1178596. doi:10.3389/fphar.2023.1178596 Parker A, Romano S, Ansorge R, Aboelnour A, Le Gall G, Savva GM, Pontifex MG, Telatin A, Baker D, Jones E, Vauzour D, Rudder S, Blackshaw LA, Jeffery G, Carding SR. Fecal microbiota transfer between young and aged mice reverses hallmarks of the aging gut, eye, and brain. Microbiome. 2022;10:68. doi:10.1186/s40168-022-01262-3 Ulluwishewa D, Anderson RC, McNabb WC, et al. Regulation of tight junction permeability by intestinal bacteria and dietary components. J Nutr. 2011;141(5):769–76. doi:10.3945/jn.110.135657 Cao L, Lee SG, Lim KT, Kim HR. Potential anti-aging substances derived from seaweeds. Mar Drugs. 2020;18(11):564. doi:10.3390/md18110564 Grzeczka A, Graczyk S, Kordowitzki P. Pleiotropic effects of resveratrol on aging-related cardiovascular diseases—what can we learn from research in dogs? Cells. 2024;13(20):1732. doi:10.3390/cells13201732 Kusaba A, Arai T. Shiitake mushroom powder supplementation increases antioxidative activity in dogs. Front Vet Sci. 2024;11:1355560. doi:10.3389/fvets.2024.1355560 Cho HW, Choi S, Seo K, Kim KH, Jeon JH, Kim CH, Lim S, Jeong S, Chun JL. Gut microbiota profiling in aged dogs after feeding pet food contained Hericium erinaceus. J Anim Sci Technol. 2022 Sep;64(5):937-949. Kaur J, Seshadri S, Golla KH, Sampara P. Efficacy and safety of standardized ashwagandha (Withania somnifera) root extract on reducing stress and anxiety in domestic dogs: A randomized controlled trial. J Vet Behav. 2022;51:8–15. Bharani KK, Devarasetti AK, Carey L, Khurana A, Kollipaka R, Hanuman DDV, Chetla VS, Banothu AK. Effects of ashwagandha (Withania somnifera) root extract on aging-related changes in healthy geriatric dogs: A randomized, double-blinded placebo-controlled study. Vet Med Sci. 2024 Sep;10(5):e1556 Sacoor C, Marugg JD, Lima NR, Empadinhas N, Montezinho L. Gut-brain axis impact on canine anxiety disorders: new challenges for behavioral veterinary medicine. Vet Med Int. 2024;2024:2856759. doi:10.1155/2024/2856759 Lee E, Carreras-Gallo N, Lopez L, Turner L, Lin A, Mendez TL, Went H, Tomusiak A, Verdin E, Corley M, Ndhlovu L, Smith R, Dwaraka VB. Exploring the effects of Dasatinib, Quercetin, and Fisetin on DNA methylation clocks: a longitudinal study on senolytic interventions. Aging (Albany NY). 2024;16(4):3088–3106. doi:10.18632/aging.205581 Bitto A, Ito TK, Pineda VV, LeTexier NJ, Huang HZ, Sutlief E, Tung H, Vizzini N, Chen B, Smith K, Meza D, Yajima M, Beyer RP, Kerr KF, Davis DJ, Gillespie CH, Snyder JM, Treuting PM, Kaeberlein M. Transient rapamycin treatment can increase lifespan and healthspan in middle-aged mice. eLife. 2016;5:e16351. doi:10.7554/eLife.16351 Urfer SR, Kaeberlein TL, Mailheau S, Bergman PJ, Creevy KE, Promislow DEL, Kaeberlein M. A randomized controlled trial to establish effects of short-term rapamycin treatment in 24 middle-aged companion dogs. GeroScience. 2017;39(2):117–127. doi:10.1007/s11357-017-9972-z Kaeberlein M, Creevy KE, Promislow DEL. The Dog Aging Project: translational geroscience in companion animals. Mamm Genome. 2016;27(7–8):279–288. doi:10.1007/s00335-016-9638- Mulder IE, Schmidt B, Lewis M, Delday M, Stokes CR, Bailey M, Aminov RI, Gill BP, Pluske JR, Mayer CD, Kelly D. Restricting microbial exposure in early life negates the immune benefits associated with gut colonization in environments of high microbial diversity. PLoS One. 2011;6(12):e28279. doi:10.1371/journal.pone.0028279 Hemida M, Vuori KA, Moore R, Anturaniemi J, Hielm-Björkman A. Early life modifiable exposures and their association with owner-reported inflammatory bowel disease symptoms in adult dogs. Front Vet Sci. 2021;8:552350. doi:10.3389/fvets.2021.552350 McMahon JE, Graves JL, Tovar AP, Peloquin M, Greenwood K, Chen FL, Nelson M, McCandless EE, Halioua-Haubold CL, Juarez-Salinas D. Translational immune and metabolic markers of aging in dogs. Sci Rep. 2025;15:14460. doi:10.1038/s41598-025-51976-3 Urfer SR, Kaeberlein M. Desexing dogs: a review of the current literature. Animals (Basel). 2019;9(12):1086. doi:10.3390/ani9121086 Santos JDP, Cunha E, Nunes T, Tavares L, Oliveira M. Relation between periodontal disease and systemic diseases in dogs. Res Vet Sci. 2019;125:136–140. doi:10.1016/j.rvsc.2019.05.011 Selting KA, Ringold R, Husbands B, Pithua PO. Thymidine kinase type 1 and C-reactive protein concentrations in dogs with spontaneously occurring cancer. J Vet Intern Med. 2016;30(4):1159–1166. doi:10.1111/jvim.13954 Urfer SR, Kaeberlein M. Desexing dogs: a review of the current literature. Animals (Basel). 2019;9(12):1086. doi:10.3390/ani9121086 Clark JD, Rager DR, Crowell-Davis S, Evans DL. Housing and exercise of dogs: effects on behaviour, immune function and cortisol concentration. Lab Anim Sci. 1997;47(5):500–510 See omnystudio.com/listener for privacy information.

Live Long and Master Aging
How Wearables Are Reshaping Healthcare | Marco Benitez

Live Long and Master Aging

Play Episode Listen Later Jul 31, 2025 30:42


As consumer wearables track everything from our heartbeats to nightly sleep cycles, a new industry has emerged—one focused on making sense of this avalanche of personal health data. In an era when prevention is prized over cure, questions abound: How accurate is the data captured on our wrists and fingers? Can these metrics truly guide us to longer, healthier lives, or are we just generating noise? For Marco Benitez, a biomedical engineer and co-founder of the health data platform Rook, the challenge isn't just about collecting the numbers but turning them into actionable insights—for both individuals and the broader healthcare world. As the medical establishment wrestles with integrating this torrent of information—and as users grapple with privacy and security—a revolution in health is quietly unfolding. Peter Bowes sat down with Benitez to discuss the promise and pitfalls of wearable data, the evolving relationship between Big Pharma and digital health, and what it will take to shift the system from sick care to prevention.___If you value our video and audio content, we would appreciate your support.Any contribution - large or small - is hugely appreciated and helps us to continue sharing insights that could help us all live longer and healthier lives. With gratitude. https://www.buzzsprout.com/87724/support PartiQlar supplementsEnhance your wellness journey with PartiQlar supplements. No magic formulas, just pure single ingredients, like NMN, L-Glutathione, Spermidine, Resveratrol, TMG and Quercetin. Get a 15% discount with the code MASTERAGING15 at PartiQlarSupport the showThe Live Long and Master Aging (LLAMA) podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice. If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.

Weird Medicine: The Podcast
639 - Quinine's FDA Ban: Sorry Cramp Sufferers!

Weird Medicine: The Podcast

Play Episode Listen Later Jul 29, 2025 41:33


Dr Steve, Dr Scott, and Lady Diagnosis discuss: What are Quercetin and Zinc used for? Can you use vascepa prophylactically? Quinine pills for leg cramps? Why was it banned by the FDA? A challenging hip pain and more Please visit: ⁠⁠⁠⁠simplyherbals.net/cbd-sinus-rinse⁠⁠⁠⁠ (the best he's ever made. Seriously.) ⁠⁠⁠⁠instagram.com/weirdmedicine⁠⁠⁠⁠ ⁠⁠⁠⁠x.com/weirdmedicine⁠⁠⁠⁠ ⁠⁠⁠⁠stuff.doctorsteve.com⁠⁠⁠⁠ (it's back!) ⁠⁠⁠⁠youtube.com/@weirdmedicine ⁠⁠⁠⁠(click JOIN and ACCEPT GIFTED MEMBERSHIPS. Join the "Fluid Family" for live recordings!) ⁠⁠⁠⁠youtube.com/@normalworld ⁠⁠⁠⁠(Check out Dave and crew, and occasionally see your old pal!) supertip.gg/drsteve (make your pals say awful things through the magic of AI) CHECK OUT THE ROADIE COACH stringed instrument trainer! ⁠⁠⁠⁠roadie.doctorsteve.com⁠⁠⁠⁠ (the greatest gift for a guitarist or bassist! The robotic tuner!) see it here: ⁠⁠⁠⁠stuff.doctorsteve.com/#roadie⁠⁠⁠⁠ Also don't forget: ⁠⁠⁠⁠Cameo.com/weirdmedicine⁠⁠⁠⁠ (Book your old pal right now because he's cheap! "FLUID!") Most importantly! ⁠⁠⁠⁠CHECK US OUT ON PATREON! ⁠⁠⁠⁠ ALL NEW CONTENT! Robert Kelly, Mark Normand, Jim Norton, Gregg Hughes, Anthony Cumia, Joe DeRosa, Pete Davidson, Geno Bisconte, Cassie Black ("Safe Slut"). Stuff you will never hear on the main show ;-) Learn more about your ad choices. Visit podcastchoices.com/adchoices

Live Long and Master Aging
AI and 3D printing deliver smart nutrition | Melissa Snover

Live Long and Master Aging

Play Episode Listen Later Jul 28, 2025 38:19


Future nutrition should be personalized, with artificial intelligence as a key driver, according to Melissa Snover, founder of Nourished, a UK-based company that makes 3D-printed gummy vitamin and supplement stacks.  She believes the current approach to supplementation and health products is outdated and poorly tailored to individual needs. Snover, registered dietitian, joined us to discuss the burgeoning field of precision nutrition. Nourished uses AI-powered algorithms to create customized nutrient gummies, based on users' lifestyle data and health goals—an approach she says offers a significant leap beyond the traditional "one size fits all" vitamin regime.  PartiQlar supplementsEnhance your wellness journey with PartiQlar supplements. No magic formulas, just pure single ingredients, like NMN, L-Glutathione, Spermidine, Resveratrol, TMG and Quercetin. Get a 15% discount with the code MASTERAGING15 at PartiQlarSupport the showThe Live Long and Master Aging (LLAMA) podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice. If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.

The Synthesis of Wellness
189. Gastrointestinal Motility | The Role of Vitamin B1 (Thiamine) in Motility and Supporting Gastrointestinal Function, and a Brief Conversation on SIBO

The Synthesis of Wellness

Play Episode Listen Later Jul 25, 2025 17:57


In this encore episode, we highlight the role of vitamin B1 (thiamine) in supporting gastrointestinal function, focusing on intestinal motility while detailing vitamin B1's involvement in acetyl-CoA and acetylcholine synthesis. We discuss thiamine insufficiency as well as how small intestinal bacterial overgrowth (SIBO) may further affect thiamine availability. We further detail host defense mechanisms—including gastric acid, pancreatic enzymes, and gastrointestinal motility—that work in concert to regulate microbial balance in the small intestine. Topics: 1. Introduction- Focus on SIBO, intestinal motility, and vitamin B1 (thiamine)  2. Small Intestine and Microbial Regulation- Low bacterial load under healthy conditions  - Protective mechanisms: gastric acid, enzymes, motility…   3. Overview of SIBO Subtypes - H₂-SIBO, hydrogen-producing bacteria  - IMO, methane-producing archaea  - H₂S-SIBO, hydrogen sulfide-producing bacteria  - Subtypes can coexist, share underlying factors   4. Host Factors in Microbial Regulation - Gastric acid, motility, pancreatic enzymes, bile acids, and immune surveillance  5. Gastric Acid and Parietal Cells  - Hydrochloric acid and intrinsic factor  - Acid environment supports digestion and microbial regulation  - Protein denaturation and pepsin activation 6. Chief Cells and Enzyme Function - Pepsinogen and gastric lipase  - Pepsinogen activated by acidic pH   7. Hypochlorhydria and Downstream Effects 8. Pancreatic Enzymes in the Small Intestine   9. Intestinal Motility and the Enteric Nervous System (ENS)- Coordinated smooth muscle contractions  - Myenteric and submucosal plexuses   10. Intestinal Wall Anatomy - Epithelium and lamina propria - Submucosa contains the submucosal plexus  - Myenteric plexus located between muscle layers   11. Vitamin B1 (Thiamine) and Gastrointestinal Function  - Acetylcholine synthesized from choline and acetyl-CoA  - Acetyl-CoA formation, thiamine availability  - Acetylcholine signaling  12. SIBO and Nutrient Availability- Bacterial overgrowth can affect nutrient absorption  - Thiaminases   13. Conclusion  - Root cause approach, multi-factorial Thank you to our episode sponsor: 1. ⁠⁠OmneDiem®'s⁠⁠ ⁠⁠Histamine Digest®⁠⁠ and ⁠⁠Histamine Digest® PureMAX⁠⁠ 2. ⁠⁠Histamine Digest® Histamine Complete⁠⁠ with DAO, Vitamin C, Quercetin, Bromelain, and Stinging Nettle Root Extract.Thanks for tuning in!Get Chloe's Book Today! "⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠75 Gut-Healing Strategies & Biohacks⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠" Follow Chloe on Instagram ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@synthesisofwellness⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Follow Chloe on TikTok @chloe_c_porterVisit ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠synthesisofwellness.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ to purchase products, subscribe to our mailing list, and more!

The Synthesis of Wellness
188. The Stomach | Symptoms of H. pylori & Hypochlorhydria, and a Conversation on the Effects of Low Stomach Acid on Micronutrient Absorption

The Synthesis of Wellness

Play Episode Listen Later Jul 18, 2025 14:47


In this episode, we detail connections between H. pylori and hypochlorhydria, while highlighting possible downstream effects on nutrient absorption. We examine how reduced gastric acidity can impair the liberation and assimilation of certain micronutrients, including iron, calcium, vitamin B12, and more; and we further discuss the impact of low stomach acid upon downstream digestive enzyme activation and gut microbial balance. The discussion also highlights the role of compromised gastric acidity in conditions such as small intestinal bacterial overgrowth (SIBO).Topics:1. Hypochlorhydria - Low stomach acid.- Aging, autoimmune gastritis, chronic PPI use, H. pylori infection.2. H. pylori - Common gram-negative bacterium that colonizes the stomach lining.- Symptoms.- Produces urease.- Ammonia neutralizes acid, creating a protective microenvironment.- Additional virulence factors and ability to form biofilms contribute to persistence.3. Gastric Anatomy & Layers- The stomach: hollow, muscular organ for mechanical and chemical digestion.- Regions: Cardia, fundus, body, and pylorus.- Layers: Mucosa, Submucosa, Muscularis externa, Serosa4. Mucosal Layer - Surface mucous cells secrete a thick bicarbonate-rich, protective mucus.- Gastric pits lead to gastric glands, which contain specialized secretory cells.5. Specialized Gastric Cells- Parietal Cells: Secrete hydrochloric acid (HCl) and intrinsic factor (IF).- Chief Cells: Secrete pepsinogen (converted to pepsin by HCl) and gastric lipase.- Role of HCl: Activates pepsin, denatures proteins, and contributes to nutrient absorption.- Intrinsic factor and vitamin B12 absorption.6. Vitamin B12 Absorption- Essential for DNA synthesis, RBC formation, neurological function.- Released from food proteins by gastric acid and pepsin.- Impaired absorption.7. Role of Gastric Acid in Broader Micronutrient Absorption- Absorption of minerals.- Soluble, ionized state.- Iron: HCl aids in preventing insoluble precipitates and supports iron absorption.8. Protective Role of Gastric Acid- Acts as a line of defense against ingested pathogens.- Maintains low microbial diversity in the stomach.- Low HCl and SIBO (Small Intestinal Bacterial Overgrowth).9. Symptoms of Low Stomach Acid- Bloating, early satiety, excessive belching.- Undigested food in stool, chronic constipation.- May reflect impaired enzymatic activation and digestive insufficiency.10. Conclusion- Multifactorial causes and downstream effects.- Optimal range of stomach acid: neither high nor low.Thank you to our episode sponsor: 1. ⁠OmneDiem®'s⁠ ⁠Histamine Digest®⁠ and ⁠Histamine Digest® PureMAX⁠ 2. ⁠Histamine Digest® Histamine Complete⁠ with DAO, Vitamin C, Quercetin, Bromelain, and Stinging Nettle Root Extract.Thanks for tuning in!Get Chloe's Book Today! "⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠75 Gut-Healing Strategies & Biohacks⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠" Follow Chloe on Instagram ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@synthesisofwellness⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Follow Chloe on TikTok @chloe_c_porterVisit ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠synthesisofwellness.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ to purchase products, subscribe to our mailing list, and more!

Biohacking Superhuman Performance
#352: Biohacker's DREAM: How Plant Exosomes Deliver Cellular Power Like Never Before | Nathalie Niddam x Dr. Jeffrey Gross

Biohacking Superhuman Performance

Play Episode Listen Later Jul 15, 2025 61:07


Today, I'm welcoming back Dr. Jeffrey Gross, a true pioneer in the regenerative longevity space. You might remember our earlier episode where we explored the transformative science of human exosomes—but today, we're going even further, straight into the fascinating world of plant exosomes.   What we discuss: Plant exosomes intro ... 00:04:23 Gut health/minerals ... 00:05:18 Why plant exosomes ... 00:08:09 Exosomes vs. liposomes ... 00:09:35 Bioavailability ... 00:12:12 Phytonutrients ... 00:17:26 Resveratrol ... 00:18:17 Quercetin ... 00:20:30 Glutathione ... 00:22:01 Antioxidant enzymes ... 00:24:02 Fruit yield per cap ... 00:25:32 Melatonin ... 00:26:55 Oral bioavailability ... 00:29:29 Research summary ... 00:30:10 Sirtuin 1/ROS ... 00:31:29 Prepping for joint regen ... 00:42:05 Cartilage success ... 00:44:00 European edge ... 00:47:48 B vitamins ... 00:48:25 Microbiome ... 00:51:50 Fisetin/dosing ... 00:53:22   Our Amazing Sponsors: Mimio - A supplement that gives you all the cellular, metabolic, and longevity benefits of a prolonged fast—even on the days when you're eating normally. Visit mimiohealth.com/nat and use code NAT FOR 20% off your first single purchase or subscription order. BEAM Minerals - are one of the most overlooked contributors to a healthy gut. They help feed and support your microbiome. Research shows that good gut bacteria rely on essential minerals like calcium, magnesium, zinc, iron, and phosphorus to thrive.. Head over to www.beamminerals.com and use code NAT20 for 20% off your first order and give your gut the simple support it deserves! Bio-Shield by Young Goose - It's a broad-spectrum serum that protects against UVA/UVB, infrared, AND high-energy visible (HEV) light—aka the stuff pouring out of your laptop right now. Visit YoungGoose.com—use code NAT10 to get started, or 5NAT if you're an existing customer.   More from Nat:  YouTube Channel Join My Membership Community Sign up for My Newsletter  Instagram  Facebook Group

Live Long and Master Aging
Treating movement as a vital sign of good health | Andrew Menter

Live Long and Master Aging

Play Episode Listen Later Jul 14, 2025 26:59


While most people regularly check their blood pressure or glucose, few consider routinely assessing their body's ability to move—and yet, this may be just as crucial to long-term health. Andrew Menter, CEO of Physmodo, joined Peter Bowes to explore the software company's mission to raise the profile of movement as a vital sign of good health. Andrew shares his personal journey from a career in law and finance to entrepreneurship in movement science, motivated in part by his athletic pursuits and the injuries that accompanied them. He discusses Physmodo's innovative use of computer vision technology, enabling self-assessment of mobility and posture via simple smartphone or tablet tools—making this once-specialized information accessible to everyone, not just elite athletes. He highlights the power of early intervention, the surprising ways movement influences sleep and mental health, and the growing importance of personalized preventive care.  PartiQlar supplementsEnhance your wellness journey with PartiQlar supplements. No magic formulas, just pure single ingredients, like NMN, L-Glutathione, Spermidine, Resveratrol, TMG and Quercetin. Get a 15% discount with the code MASTERAGING15 at PartiQlarSupport the showThe Live Long and Master Aging (LLAMA) podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice. If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.

The Synthesis of Wellness
187. Intestinal Mycobiome | Small Intestinal Fungal Overgrowth, Biofilm Formation & Microbial Persistence, and Intestinal Barrier Integrity

The Synthesis of Wellness

Play Episode Listen Later Jul 11, 2025 14:52


In this episode, we detail Small Intestinal Fungal Overgrowth (SIFO), with a focus on fungal biofilm formation and its role in promoting microbial persistence and evasion of host immune responses. We discuss the phenotypic plasticity of Candida species, as well as biofilm matrices adherent to the intestinal mucosa. We further highlight common symptoms of SIFO as well as the effects of hypochlorhydria, reduced pancreatic enzyme and bile output, impaired motility, diminished commensal bacterial populations, and weakened mucosal immunity.Topics: 1. Introduction- Focus on the gut mucosal barrier.- Emphasis on Small Intestinal Fungal Overgrowth (SIFO) and biofilms.2. Intestinal Barrier Anatomy- The mucosa: epithelium, lamina propria, and a thin band of smooth muscle.- The epithelial layer.- Covered by protective mucus composed of mucin glycoproteins secreted by goblet cells.- In the small intestine: less dense mucus.3. Epithelial Integrity- Tight junctions.- Paracellular barrier preventing uncontrolled antigen passage.4. Lamina Propria5. Overview of Small Intestinal Fungal Overgrowth (SIFO)- SIFO involves fungal overgrowth in the small intestine, commonly Candida species.- Small intestines: Low microbial density due to motility, gastric acid, bile acids, immune surveillance, and more.- Contributing factors: hypochlorhydria, impaired motility, reduced digestive enzymes, diminished competitive flora, lowered immunity, and more.6. Candida Pathogenicity- Candida exhibits phenotypic plasticity: yeast and hyphal forms.- Biofilm formation.7. Biofilm Formation- Biofilms are structured communities of microbes within a self-produced extracellular matrix.- Resistance to antimicrobials and immune defenses.- Can develop on intestinal mucosa and in various other regions.8. SIFO and SIBO Overlap- Root causes and overlap between SIFO and Small Intestinal Bacterial Overgrowth (SIBO).- Common symptoms.9. Gastric Acid in More Detail- Stomach epithelium includes mucous, parietal, chief, and enteroendocrine cells- Parietal cells secrete hydrochloric acid.- HCl denatures proteins and aids in inhibiting pathogens.- Hypochlorhydria: possible causes. 10. Downstream Effects of Low Acid11. Gut Motility in More Detail- Motility involves rhythmic smooth muscle contractions.- Enteric nervous system (ENS): myenteric and submucosal plexuses.- Dysautonomia and motility.12. SIFO Contributing Factors13. Candida Regulation- Candida generally remains in unicellular yeast form under homeostatic regulation.- Controlled by microbial competition, host defenses, antifungal peptides, and more.14. Role of Mucus and sIgA- Mucosal immunity (including sIgA) aids in regulating Candida populations.- Low sIgA levels (due to stress, immune suppression, dysbiosis,…) weaken defense 15. Conclusion- Mucosal barrier structure.- SIFO and Candida.- Biofilm formation, microbial persistence, and mucosal disruption.- SIFO and SIBO.- Multifactorial nature of fungal dysbiosis, types of biofilms, and small intestinal overgrowth.Thank you to our episode sponsor: 1. OmneDiem®'s Histamine Digest® and Histamine Digest® PureMAX 2. Histamine Digest® Histamine Complete with DAO, Vitamin C, Quercetin, Bromelain, and Stinging Nettle Root Extract.Thanks for tuning in!Get Chloe's Book Today! "⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠75 Gut-Healing Strategies & Biohacks⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠" Follow Chloe on Instagram ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@synthesisofwellness⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Follow Chloe on TikTok @chloe_c_porterVisit ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠synthesisofwellness.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ to purchase products, subscribe to our mailing list, and more!

Dr. Ruscio Radio: Health, Nutrition and Functional Medicine

Today I'm happy to chat with our patient Leslie who shares her successful journey with histamine intolerance healing. We'll go through how SIBO led to her histamine issues, the connection to low vagus nerve tone, as well as the low histamine diet and treatments such as dao enzymes. Tune in to learn how you can reduce histamine in the body naturally.    Start healing with us! Learn more about our virtual clinic:  https://drruscio.com/virtual-clinic/ Histamine Intolerance and Diet Guide: https://drruscio.com/guides/get-histamine-intolerance-guide/  

Intelligent Medicine
ENCORE: Leyla Weighs In: Navigating Detox--Key Foods and Nutrients for Liver Health

Intelligent Medicine

Play Episode Listen Later Jul 4, 2025 23:49


Nutritionist Leyla Muedin explores the significance of detoxification and its impact on overall health. She highlights the role of the liver in detoxification and discusses how various foods and nutrients can support liver function to optimize detoxification pathways. Leyla covers the importance of consuming organic produce, clean seafood, and minimizing exposure to toxins found in household products, medications, and certain foods. She also details the phase one and phase two enzymes involved in detoxification, the importance of specific vitamins, minerals, and amino acids, and the signals that might indicate the need for liver support. Lastly, she encourages listeners to make healthier dietary choices and lifestyle changes to support their liver and overall well-being.

Forever Young Radio Show with America's Natural Doctor Podcast
Episode 608: Ep 608 Immune Health and Allergies ..think 5 in 1 _Qummune for Year round support!.mp3

Forever Young Radio Show with America's Natural Doctor Podcast

Play Episode Listen Later Jun 10, 2025 46:32


 Immune Health and Allergies ..think 5 in 1 Qummune for Year round support!Flavonoids..... Let's start with one that is classified as a Flavonoid, and thatis Quercetin.We also dive into Liposomal delivery,Do you have allergies and immune issues?  → Can Quercetin be found in food?→ What is the difference between Quercetin & Quercetin Phytosome?→ What are branded ingredients? → Vitamin C is also a go to for people hoping to supportdaily Immune function. But not all Vitamin C is the same.→ Zinc rich foods people can add in? → D3/K2-Why should they be taken together??→ Absorption seems to be the key whether it be food or Supplements.→ Lab tested and certified for potency and purity. Why isthis important?Guest: Amber Lynn Vitale, CN is Board Certified in Holistic Nutrition®and a Certified Dietary Supplement Professional™. She is also anAyurvedic Clinical Consultant on faculty with Wild Rose College ofHerbal Medicine, and on the advisory board for Natural Practitionerand Taste for Life magazines.Amber's journey in the healing arts developed richly as she workedfor years in practices with Integrative Physicians, Acupuncturists,Chiropractors, and Nurses. Since 2008 she has been producingwritten and video educational content for many publications, aneducational YouTube channel, and Instagram and Facebook pages.By 2012 she had realized that raw materials sourcing, labelingtransparency, legitimate certifications, and educational supportwere the criteria that would set quality natural products brandsapart from the rest; and she made it her mission to educateboth the practitioner and the public about the standards thatensure a reliable product.  Recently she founded Trifecta ForHealth, LLC using her years of experience to develop synergistichealth protocols tailored to individual needs, and provide brandsupport for the best supplemental products currently available.Learn more about Amber  Learn More about Qummune 5 in 1 Immune Support (Use the code Forever25 to save 25% OFF)  Read the research

Dr. Berg’s Healthy Keto and Intermittent Fasting Podcast
Onion Juice for Extreme Hair Growth: Stop Hair Loss

Dr. Berg’s Healthy Keto and Intermittent Fasting Podcast

Play Episode Listen Later May 27, 2025 6:17


Onion juice is a natural hair loss remedy for many different types of hair loss. Whether autoimmune, nutritional, or fungal, onion juice can help stop hair loss naturally and stimulate natural hair growth quickly. Onions are loaded with sulfur, an essential building block for keratin, the protein that builds your hair. Onions have a high amount of quercetin, which is beneficial for autoimmune hair loss cases caused by alopecia. Quercetin helps increase the growth hormones of the hair follicle. It's also a powerful antimicrobial, so it can help protect the scalp against the overgrowth of yeast, fungus, and mold. To use onion juice for hair growth, chop one red onion and blend it in a blender. Put the blended onion through a cheesecloth to separate the liquid from the pulp. Massage the liquid into your scalp for a few minutes in the shower. Don't rinse! Allow the onion juice to sit in your hair for 30 minutes to 1 hour.Rinse your hair and shampoo twice to remove onion odor. Do this twice per week for 4 to 6 weeks. You should notice hair growth after week 3 or 4!To increase the benefits of onion juice for hair, add 5 drops of rosemary oil. In a 2015 randomized trial, rosemary oil was found to be as effective as one of the top medications for alopecia. Rosemary oil has several anti-inflammatory and antioxidant phytonutrients that increase blood flow to the scalp.While onion juice for hair has been proven effective, fermenting it can increase its effectiveness! To do this, combine onion juice, 8 ounces of water, a teaspoon of sea salt, and a ½ teaspoon of raw honey in a glass or mason jar.Cover the mixture with a cheesecloth and allow it to ferment at room temperature for 72 hours. This enhances the quercetin in the onion juice, increasing hair growth. Put the mixture through a cheesecloth to separate the liquid.If you're experiencing hair loss, taking 10,000 to 20,000 IU of vitamin D daily is very beneficial. A healthy diet is also imperative!Dr. Eric Berg DC Bio:Dr. Berg, age 60, is a chiropractor who specializes in Healthy Ketosis & Intermittent Fasting. He is the author of the best-selling book The Healthy Keto Plan, and is the Director of Dr. Berg Nutritionals. He no longer practices, but focuses on health education through social media.

Better with Dr. Stephanie
Fat Loss, Muscle Gains & Menopause: Science That Actually Works with Abbie Smith-Ryan PhD

Better with Dr. Stephanie

Play Episode Listen Later May 26, 2025 76:55


Abbie Smith-Ryan PhD, an expert in exercise and nutritional strategies for women's health, especially during perimenopause, menopause and obesity, discusses evidence-based methods to accelerate fat loss, increase muscle mass, and improve well-being and longevity for women. Topics include accurate body composition measurement, the role of protein and fibre, optimizing pre- and post-exercise fueling, metabolic adaptation, and supplements like Omega-3s, vitamin D, magnesium, and creatine. Dr. Smith-Ryan also stresses consistent, varied exercise routines and mental and physical recovery.Episode Overview (timestamps are approximate):(0:00) Intro/Teaser(11:00) Nutrition for Body Recomposition(22:00) Nutrient Timing Pre and Post Exercise(32:00) Protein Intake for Women(43:00) The Benefits of Inefficiencies(48:00) Optimal Exercise Frequency and Variety(56:00) Key Supplements for Women's Health(1:05:00) Optimizing Perimenopause Nutrition & Recovery(1:12:00) The “After Party” with Dr. StephanieResources mentioned in this episode can be found at https://drstephanieestima.com/podcasts/ep418/A huge thanks to our sponsors:TIMELINE - Improve energy at the cellular level with Mitopure. Save 10% at https://timelinenutrition.com/better with code BETTER.ONESKIN  - Use the power of peptides for firmer, glowing skin. Save 15% at https://oneskin.co/better with code BETTER.LVLUP - Midlife hormonal changes can wreak havoc on your gut health. Ultimate GI Repair combines powerful gut-healing peptides BPC-157, Larazotide Acetate and KPV with gut-nourishing naturals like Zinc L-Caronsine, EMIQ, Quercetin and Tributyrin to soothe your changing digestion. To learn more, visit https://lvluphealth.com/DRSTEPHANIE and use code DRSTEPHANIE for 15% off.BODYBIO - Support your health with Fish Oil Plus. Great straight or in smoothies! Use code BETTER at https://bodybio.com/better for 15% off.

During the Break
Quercetin: A Powerful Antioxidant That's More Than Just Allergy Support from The Holistic Navigator

During the Break

Play Episode Listen Later May 24, 2025 33:05


An episode from The Holistic Navigator. This is not to diagnosis or treat any disease/illness. Consult your physician before taking supplements or medications OR before you stop taking medications. This is for entertainment/informational purposes only! Quercetin is a funny sounding nutrient that isn't joking around. It's an antioxidant that's found in plants that is most often associated with sinus and allergy support, but it's a powerhouse that should be considered as a daily supplement. From athletes, allergy sufferers, or anyone exposed to respiratory stressors, quercetin is a wonderful supplement with a plethora of benefits. Meet John Mills: On this week's episode we speak with John Mills, Director of Quality and Compliance at Highland Laboratories in Mt. Angel, Oregon. John walks us through an overview of the general benefits and then looks at a specific quercetin formulation from Mt. Angel Vitamins that includes Zinc, Bromelain, Stinging Nettles, Vitamin-C and Vitamin-D3. He gives us great information about dosing, when and how to take it, and how it should be in everyone's cabinet and part of a daily routine! Some Questions We Discuss: What is quercetin and what are the benefits of it? (5:14) Who might benefit from taking quercetin daily? (8:43) What makes quercetin different from other histamine blockers? (11:55) Can you take too much quercetin?(13:35) Are there any medications that quercetin negatively interacts with? (18:43) Some Key Takeaways From This Episode: Quercetin has surprising benefits for athletes due to its antioxidant effects. (6:16) People with allergies, seasonal or in general, can benefit greatly from quercetin. (8:55) We are overwhelmed with environmental stressors that hurt our lungs so we need to support them. (10:03) Everyone needs to be taking zinc supplements. (14:32) Increase Vitamin C levels when taking quercetin. (18:55) Quercetin may be better suited as a preventative as opposed to a response. (24:18)

The Red Light Report
Research: The Mitochondrial Connection to Oral Health

The Red Light Report

Play Episode Listen Later May 22, 2025 52:48


In this solo episode of The Red Light Report, Dr. Mike explores the profound connection between mitochondrial health and oral disease. He reviews three recent studies highlighting how red light therapy, methylene blue, and compounds like urolithin A can support oral tissues, reduce inflammation, and even impact systemic conditions like diabetes and neurodegeneration. From root canal innovations to mitophagy in periodontitis, this episode is full of cutting-edge insights and practical applications for anyone interested in longevity, biohacking, or oral health optimization.Key Topics Covered:Study #1: Methylene Blue + Graphene Oxide for Root Canal Photodynamic Therapy• Combining methylene blue and reduced graphene oxide with red light therapy significantly improves antibacterial and antifungal effects in root canals.• Highlights the synergy between methylene blue and red light.• Dr. Mike shares how his nighttime routine—using BioBlue Calm and a red-light toothbrush—may create a low-level photodynamic therapy effect in the mouth.Study #2: Mitophagy in Periodontal Disease• Mitophagy (mitochondrial autophagy) plays a key role in managing inflammation, bone remodeling, and cell death in gum disease.• Key interventions to enhance oral mitophagy:• Urolithin A (strong Pink1/Parkin pathway activator)• Resveratrol, Melatonin (support mitochondrial quality)• Berberine, Curcumin, Metformin (via AMPK activation)• NR, Quercetin (via SIRT1 + PGC-1α pathway)Study #3: Mitochondrial Dysfunction Links Oral and Systemic Diseases• Periodontitis driven by mitochondrial dysfunction is linked to diseases like diabetes, cardiovascular disease, and neurodegeneration.• Key issues:• Impaired mitochondrial fusion/fission, biogenesis, and mitophagy.• Excessive ROS and mitochondrial DNA leakage fuel inflammation.• Poor mitochondrial function impairs periodontal stem cell regeneration.• Therapeutic approaches:• Antioxidants (CoQ10, resveratrol, melatonin, curcumin, EGCG)• Photodynamic therapy (methylene blue + red light)• Mitochondria-targeted compounds to modulate apoptosis and inflammation.Dr. Mike's Takeaways• Oral mitochondrial health is foundational—not isolated from systemic health.• Red light therapy and methylene blue offer powerful synergistic effects, even in oral applications.• A mitochondria-first approach may provide long-term protection against oral and systemic disease.   If you found the information in today's episode particularly interesting and/or compelling, please share it with a family member, friend, colleague and/or anyone that you think could benefit and be illuminated by this knowledge. Sharing is caring :)As always, light up your health! - Key points: 00:00 – Introduction: Mitochondrial Health & Podcast Focus 00:32 – Announcements: Health Alchemy Bundle & Upcoming Events 06:18 – Study 1: Methylene Blue & Red Light Therapy for Root Canal Treatment 08:42 – Methylene Blue Benefits Recap 13:37 – Study 1 Discussion: Photodynamic Therapy Enhancements 16:57 – Practical Application: Methylene Blue for Oral Health 19:40 – Study 2: Mitophagy in Periodontal Disease 23:46 – Targeted Mechanisms to Enhance Mitophagy 28:42 – Study 3: Mitochondrial Dysfunction in Periodontitis & Systemic Diseases 31:38 – Therapeutic Strategies for Mitochondrial Health 41:44 – Integrative Mitochondrial Therapies 47:02 – Conclusion: Mitochondrial Dysfunction as a Core Issue 50:45 – Closing Thoughts & Upcoming Events - Articles referenced in episode:Synthesis, characterization, and application of methylene blue functionalized reduced graphene oxide for photodynamic therapy in root canal treatmentMitophagy and Its Significance in Periodontal DiseaseMitochondrial Dysfunction in Periodontitis and Associated Systemic Diseases: Implications for Pathomechanisms and Therapeutic Strategies - Get over $6,000 worth of wellness education from top experts for $50! The Health Alchemy BundleThis is an amazing opportunity put together by Carrie Bennett and Sarah Kleiner! This Bundle is collection of 60+ eBooks, courses, and other resources available for $50 at a mind-blowing 99% discount.     This massive collection of resources is rooted in the science + spirituality of healing with nature, which cover topics like: Circadian & quantum biology Mental, emotional, & spiritual health Nutrition, minerals, & supplementation (when necessary) Herbalism & homeopathy Movement, posture, & fitness Hormonal health, pregnancy, & parenting And even specific issue support—from healing autoimmunity to improving sleep, & more This is a limited opportunity that goes through TOMORROW, May 23rd, so act now and don't miss out!   Get The Health Alchemy Bundle by clicking here! - Upcoming BioLight Events:   Biohacking Conference - May 28 - 30 (Austin, TX)   Returning to Nature (Quantum Health Retreat), June 26 - 27 (Franklin, TN) - Introducing the Newest BioBlue Supplement! The most comprehensive, powerful mitochondrial support supplement on the market ...   What is The Fountain of Youth in simple terms? An unparalleled supplement for brain power, energy, and longevity This supplement is like a high-performance tune-up for your brain and body. It combines powerful natural and science-backed ingredients to help you think clearer, feel more energized, and support your long-term health.The BioBundle automatically saves you 15% on both of the supplements you choose.   For the next two weeks, SAVE 20% on your order of BioBlue Fountain of Youth! Simply use code FOY20 Code expires 5/29, midnight PST   Click here to check out BioBlue Fountain of Youth - Dr. Mike's #1 recommendations: Water products: Water & Wellness Grounding products: Earthing.com EMF-mitigating products: Somavedic Blue light-blocking glasses: Ra Optics - Stay up-to-date on social media: Dr. Mike Belkowski: Instagram LinkedIn   BioLight: Website Instagram YouTube Facebook

The Cabral Concept
3389: Magnesium Supplement Advice, Creatine & Pregnancy, MTHFR & COMT, Super CitriMax & Weight Loss, High Heart Rate & Alcohol, Blood in Stool (HouseCall)

The Cabral Concept

Play Episode Listen Later May 17, 2025 19:52


Welcome back to our weekend Cabral HouseCall shows! This is where we answer our community's wellness, weight loss, and anti-aging questions to help people get back on track! Check out today's questions:    Felicia: Hello Dr. Cabral. What are your thoughts on this magnesium supplement ? Magnesium bisglycinate, fillers (microcrystalline cellulose, dicalcium phosphate), anti-caking agents (silicon dioxide, magnesium stearate), coating agents (hydroxypropyl methylcellulose, glycerol). Worth taken or should I look for another one? Thanks for your help                              Audrey: Hi Dr. Cabral, Thank you for being my go to person for all of my health questions! What are your thoughts on taking creatine while pregnant? I am going to keep strength training throughout my pregnancy and am hoping this helps with maintaining some muscle. I've read great things about it helping mom and baby but want to know what you think. I know you cannot give medical advice. Thanks                                                                                                                               Elsa: Hi Dr. Cabral! Thanks for all the information you provide. I'm a fairly recent listener but already have learned so much from you. May God continue to bless you, your family, and your team. My question is regarding my husband. He did a genetic test and came out positive for the MTHFR heterozygous A1298C and COMT heterozygous G472A (Val108/158Met). I've listened to your recent podcasts on COMT, but my question is regarding supplements to avoid if you have this variant. He doesn't take any medications, and already takes methylated B complex to support MTHFR and high homocysteine levels (8.3). He also takes Vit C, Zinc+Copper, Mag, Vit D+K2, Omega 3s, Probiotics. The test results indicate to avoid Quercetin and Green Tea because they are COMT inhibitors? True? Thanks.                                        Bettina: Hello Dr. Cabral. What are your thought on Super CitriMax for weightloss using a combination of 4500 mg Garcinia Cambogia with 60% HCA with 600 mg of Chromium and 1000 mg of B3 Niacinamide or B3 Nicotinamide? Thanks for your thoughts on this.                                                                                             Hannah: Hi Dr Cabral! I wrote in when you said the que was closer to 2-3 weeks and I haven't heard my question yet so this is incase my question got lost- myself and a couple of people I've met recently get an elevated heart rate when drinking alcohol (even 1 drink). This has never happened to me before and I'm very well hydrating prior, what else besides histamines could this be? Second, I have a very scant amount of blood per rectum every couple of days since starting the CBO, have you heard of this happening? I'm thinking to d/c citricidal early, I didn't test prior to CBO and only have 3 days left of that to see if it's related. Thanks for everything!!                           Thank you for tuning into today's Cabral HouseCall and be sure to check back tomorrow where we answer more of our community's questions!    - - - Show Notes and Resources: StephenCabral.com/3389 - - - Get a FREE Copy of Dr. Cabral's Book: The Rain Barrel Effect - - - Join the Community & Get Your Questions Answered: CabralSupportGroup.com - - - Dr. Cabral's Most Popular At-Home Lab Tests: > Complete Minerals & Metals Test (Test for mineral imbalances & heavy metal toxicity) - - - > Complete Candida, Metabolic & Vitamins Test (Test for 75 biomarkers including yeast & bacterial gut overgrowth, as well as vitamin levels) - - - > Complete Stress, Mood & Metabolism Test (Discover your complete thyroid, adrenal, hormone, vitamin D & insulin levels) - - - > Complete Food Sensitivity Test (Find out your hidden food sensitivities) - - - > Complete Omega-3 & Inflammation Test (Discover your levels of inflammation related to your omega-6 to omega-3 levels) - - - Get Your Question Answered On An Upcoming HouseCall: StephenCabral.com/askcabral - - - Would You Take 30 Seconds To Rate & Review The Cabral Concept? The best way to help me spread our mission of true natural health is to pass on the good word, and I read and appreciate every review!  

advice blood alcohol pregnancy weight loss omega supplement probiotics may god magnesium cabral creatine cbo stool green tea heart rate mthfr chromium free copy comt hca quercetin vit c high heart garcinia cambogia complete stress complete omega metabolic vitamins test test mood metabolism test discover complete food sensitivity test find inflammation test discover complete candida
Live Long and Master Aging
Practical lifestyle changes to become ageless | Dr. Michael Aziz

Live Long and Master Aging

Play Episode Listen Later May 11, 2025 37:38


Think of aging as syndrome that can be overcome to live the best life possible.  Dr. Michael Aziz, author of The Ageless Revolution, takes this approach to promote longevity and overall well-being, based on the principles of functional medicine. In our conversation, he emphasizes the need for a holistic - whole body - approach to health, and advocates for practical lifestyle changes, including dietary adjustments and intermittent fasting, to promote longevity and overall well-being. The New York City-based physician is a sharp critics of US dietary guidelines, which he sees as outdated. He says they have contributed to the poor health of millions of people. He is also keen to distinguishes between superficial “anti-aging” and deeper, cellular-level “pro-aging” interventions.------This podcast is supported by affiliate arrangements with a select number of companies. We have arranged discounts on certain products and receive a small commission on sales. The income helps to cover production costs and ensures that our interviews, sharing information about human longevity, remain free for all to listen. Visit our SHOP for more details and thanks for your support!  PartiQlar supplementsEnhance your wellness journey with PartiQlar supplements. No magic formulas, just pure single ingredients, like NMN, L-Glutathione, Spermidine, Resveratrol, TMG and Quercetin. Get a 15% discount with the code MASTERAGING15 at PartiQlarSupport the showThe Live Long and Master Aging (LLAMA) podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice. If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.

Podcast Notes Playlist: Latest Episodes
The Biohacks Big Pharma Doesn't Want You to Know: Plasmapheresis, Muse Cells & Peptides

Podcast Notes Playlist: Latest Episodes

Play Episode Listen Later May 9, 2025


Doctor's Farmacy with Mark Hyman, MD: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday --------- Cutting-edge medical advances are unlocking new ways to slow aging and enhance health. Plasmapheresis removes harmful inflammatory molecules, toxins, and cellular waste from plasma, helping to reduce biological aging and improve resilience. Muse cells, a powerful form of stem cell therapy, show promise in regenerating tissue and treating complex conditions like ALS and stroke. And peptides—small, naturally occurring signaling molecules—support healing, immune balance, and cellular repair, offering practical tools for longevity and optimized health. In this episode, I talk with Dr. Darshan Shah, Dr. Adeel Khan, and Dr. Edwin Lee about medical advancements that are the ultimate longevity biohacks. Dr. Darshan Shah is a board-certified surgeon, longevity medicine expert, author, and founder of Next Health—the world's largest Health Optimization and Longevity clinic. He has performed over 20,000 surgical procedures and advised thousands on extending healthspan and lifespan. A prodigy in medicine, Dr. Shah earned his MD at 21 and trained at the Mayo Clinic. He has since launched multiple health ventures, authored a book, and patented medical devices. Committed to ongoing learning, he holds alumni status at Harvard Business School and Singularity University. Dr. Shah is a sought-after speaker on health and longevity. Dr. Adeel Khan, M.D. is a cell and gene therapy specialist with a visionary approach that is changing the way we perceive healthcare worldwide. Khan has cemented his reputation as a regenerative medicine expert and a driven entrepreneur. Dr. Edwin Lee is a board-certified endocrinologist, author, and international speaker specializing in hormonal balance, regenerative, and functional medicine. He founded the Institute for Hormonal Balance in Orlando in 2008 and completed fellowships in Critical Care and Endocrinology at the University of Pittsburgh. Dr. Lee is the lead investigator of an IRB-approved senolytic study exploring compounds like Dasatinib, Quercetin, and Fisetin, and recently published the first human trial using BPC157 for knee pain. He is an assistant professor at the University of Central Florida College of Medicine, co-founder of the Clinical Peptide Society, and founder of SavePeptides.org. His latest book is The Fountain of Youth with Peptides. This episode is brought to you by BIOptimizers. Head to bioptimizers.com/hyman and use code HYMAN10 to save 10%. Full-length episodes can be found here: This Breakthrough Blood Therapy Could Add Years To Your LifeStem Cells & Peptides: The Secret to Reversing Chronic Pain and Aging?How Peptides Enhance Healing and Longevity

feelgoodery
Allergy Season Survival Guide: Natural Remedies & Daily Habits That Actually Help

feelgoodery

Play Episode Listen Later May 8, 2025 23:49


If there's one thing a lot of people are battling right now, it's seasonal allergies — and with the sniffles, the sneezes, and the brain fog, it's more than just annoying. In today's episode - we're revisiting my 7 top natural supports, plus a new method I've been incorporating this season. Whether you're dealing with itchy eyes, nonstop sneezing, or that can't-quite-think-straight kind of fog, this episode's for you.We're Covering:What's actually happening in your body when allergies strikeThe difference between allergy symptoms and a coldWhy staying hydrated helps control histamine (your allergy culprit)The surprising herbal tea with antihistamine benefitsThe plant pigment that can naturally reduce inflammationSpirulina: gross but effective (and how to make it bearable)Homeopathic optionsThe one thing to do before bed to reduce nighttime symptomsHow bursts of movement may actually help clear out congestionAnd the underrated power of kindness as medicineResources Mentioned:Sabadilla (homeopathic remedy for sneezing)RhinAllergy by Boiron (combination homeopathic formula)Stinging Nettle Tea (herbal support with antihistamine properties)Quercetin-rich foods: red onion, broccoli, raspberries, apples, parsleyVitamin C (bonus support during allergy season)Spirulina (immune-modulating blue-green algae)And if this episode helped clear your head — or just made you laugh through your congestion — feel free to send it to a friend, leave a kind review, or shout us out. It makes a real difference.Disclaimer: The information shared in this podcast is for informational purposes only and is not a substitute for medical advice. Please consult your healthcare provider for personalized support.

The Doctor's Farmacy with Mark Hyman, M.D.
The Biohacks Big Pharma Doesn't Want You to Know: Plasmapheresis, Muse Cells & Peptides

The Doctor's Farmacy with Mark Hyman, M.D.

Play Episode Listen Later May 5, 2025 63:56


Cutting-edge medical advances are unlocking new ways to slow aging and enhance health. Plasmapheresis removes harmful inflammatory molecules, toxins, and cellular waste from plasma, helping to reduce biological aging and improve resilience. Muse cells, a powerful form of stem cell therapy, show promise in regenerating tissue and treating complex conditions like ALS and stroke. And peptides—small, naturally occurring signaling molecules—support healing, immune balance, and cellular repair, offering practical tools for longevity and optimized health. In this episode, I talk with Dr. Darshan Shah, Dr. Adeel Khan, and Dr. Edwin Lee about medical advancements that are the ultimate longevity biohacks. Dr. Darshan Shah is a board-certified surgeon, longevity medicine expert, author, and founder of Next Health—the world's largest Health Optimization and Longevity clinic. He has performed over 20,000 surgical procedures and advised thousands on extending healthspan and lifespan. A prodigy in medicine, Dr. Shah earned his MD at 21 and trained at the Mayo Clinic. He has since launched multiple health ventures, authored a book, and patented medical devices. Committed to ongoing learning, he holds alumni status at Harvard Business School and Singularity University. Dr. Shah is a sought-after speaker on health and longevity. Dr. Adeel Khan, M.D. is a cell and gene therapy specialist with a visionary approach that is changing the way we perceive healthcare worldwide. Khan has cemented his reputation as a regenerative medicine expert and a driven entrepreneur. Dr. Edwin Lee is a board-certified endocrinologist, author, and international speaker specializing in hormonal balance, regenerative, and functional medicine. He founded the Institute for Hormonal Balance in Orlando in 2008 and completed fellowships in Critical Care and Endocrinology at the University of Pittsburgh. Dr. Lee is the lead investigator of an IRB-approved senolytic study exploring compounds like Dasatinib, Quercetin, and Fisetin, and recently published the first human trial using BPC157 for knee pain. He is an assistant professor at the University of Central Florida College of Medicine, co-founder of the Clinical Peptide Society, and founder of SavePeptides.org. His latest book is The Fountain of Youth with Peptides. This episode is brought to you by BIOptimizers. Head to bioptimizers.com/hyman and use code HYMAN10 to save 10%. Full-length episodes can be found here: This Breakthrough Blood Therapy Could Add Years To Your LifeStem Cells & Peptides: The Secret to Reversing Chronic Pain and Aging?How Peptides Enhance Healing and Longevity

Vitality Radio Podcast with Jared St. Clair
#531: Breathe Easy: Natural Solutions for Seasonal Allergies

Vitality Radio Podcast with Jared St. Clair

Play Episode Listen Later May 3, 2025 54:32


Tis the season for itchy, watery eyes and runny, stuffy noses! But you don't have to suffer and there are lots of approaches for comprehensive relief from seasonal allergies. On this episode of Vitality Radio, Jared invites Ben Fuehrer from Utzy Naturals to discuss their Allurtica allergy formula, and how each of its key ingredients work to provide fast relief from allergy symptoms. They also discuss the importance liver health, and lifestyle habits that can help your body handle the season's allergens. Jared also chats with our Homeopathic Consultant, Amanda Kotter, about the synergy between homeopathic remedies that work great alongside Allurtica and on their own for seasonal allergy support!Products:Utzy AllurticaClearLife AllergyAllium CepaOmega-3Precision ProbioticLiverVitalityB5 Pantothenic AcidAdditional Information:#498: Cardiovascular and Metabolic Health Without Drugs with Ben Fuehrer#429: Homeopathic Formulas for Pain, Cold and Flu, and Seasonal Allergies with Marie CamilleTo schedule your Homeopathy Consultation with Amanda:Email Amanda@vitalitynutrition.comCall/Text 801-388-4133Visit the podcast website here: VitalityRadio.comYou can follow @vitalitynutritionbountiful and @vitalityradio on Instagram, or Vitality Radio and Vitality Nutrition on Facebook. Join us also in the Vitality Radio Podcast Listener Community on Facebook. Shop the products that Jared mentions at vitalitynutrition.com. Let us know your thoughts about this episode using the hashtag #vitalityradio and please rate and review us on Apple Podcasts. Thank you!Just a reminder that this podcast is for educational purposes only. The FDA has not evaluated the podcast. The information is not intended to diagnose, treat, cure, or prevent any disease. The advice given is not intended to replace the advice of your medical professional.

Podcast Notes Playlist: Nutrition
Mold, Lyme, Gut Health, and the Mystery of Histamine Intolerance

Podcast Notes Playlist: Nutrition

Play Episode Listen Later May 2, 2025 65:49


Doctor's Farmacy with Mark Hyman, MD Key Takeaways  Histamine intolerance and mast cell activation syndrome (MCAS) can be the hidden drivers behind a wide range of chronic conditions, such as fatigue, brain fog, food sensitivities, and skin issues – yet, histamine intolerance is often overlooked by conventional medicineMCAS is a condition where certain immune cells – called mast cells – release too many chemicals (like histamine) at the wrong timesUsing diet as a short-term therapeutic tool: A low-histamine diet or Low-FODMAP Dietis not a lifelong diet because tons of healthy foods have histamine in them Consume the freshest foods possible and avoid leftovers, as histamine levels in food rise over time after preparationFoods that are traditionally categorized as “healthy” may be contributing to your histamine issues; these include: aged meats, cheeses, fermented foods, and dairy Even though they are generally healthy, consuming them is like throwing gas on your histamine fire Implementing a low-histamine diet in three phases Phase 1 – remove alcohol, especially beer, wine, and champagne Phase 2 – remove canned and smoke fish (examples: anchovies), processed and fermented meats, aged cheese, pickled and fermented foods (sauerkraut, kimchi, yogurts, kefir, mustard, ketchups, vinegar, soy sauce)   Phase 3 – remove plant foods such as spinach, avocado, tomatoes, pineapples, citrus foods Treat IBS with a low-FODMAP diet, which is specifically designed to reduce the fermentable carbohydrates that gut bacteria feed on; this helps reduce: gas production, bloating, bacterial Foods to avoid: Garlic, onions, wheat, legumes, milk, soft cheeses, apples, honey, sorbitol, xylitol, stone fruits, artificial sweetenersFoods to consume: Carrots, spinach, bananas, chicken, rice, cheddar cheese, eggsSupplement to support healthy histamine levels:Quercetin – a natural plant compound that helps people with mast cell issues, histamine intolerance, and allergies (with additional benefits to metabolic function) Read the full notes @ podcastnotes.orgMany people struggle with mysterious symptoms like fatigue, brain fog, food sensitivities, and skin issues—only to be misdiagnosed or dismissed altogether. This conversation highlights how histamine intolerance and mast cell activation syndrome can be the hidden drivers behind a wide range of chronic conditions, and why they're often overlooked in conventional medicine. From the role of gut health, food triggers, and environmental toxins to deeper root causes like Lyme disease or mold exposure, it's clear that personalized, Functional Medicine is key to uncovering real answers. Understanding the immune system's role in histamine reactions—and how even “healthy” foods can be inflammatory for some—is a critical step toward healing. In this episode, I talk with Dr. Todd LePine, Dr. Elizabeth Boham, and Dr. Mark Pimentel about what histamine intolerance is, how it can be related to gut health, and why it's important to address it. Dr. Todd LePine graduated from Dartmouth Medical School and is Board Certified in Internal Medicine, specializing in Integrative Functional Medicine. He is an Institute for Functional Medicine Certified Practitioner. Prior to joining The UltraWellness Center, he worked as a physician at Canyon Ranch in Lenox, MA, for 10 years. Dr. LePine's focus at The UltraWellness Center is to help his patients achieve optimal health and vitality by restoring the natural balance to both the mind and the body. His areas of interest include optimal aging, bio-detoxification, functional gastrointestinal health, systemic inflammation, autoimmune disorders, and the neurobiology of mood and cognitive disorders. Dr. LePine enjoys skiing, kayaking, hiking, camping, and golfing in the beautiful Berkshires, and is a fitness enthusiast. Dr. Elizabeth Boham is Board Certified in Family Medicine from Albany Medical School, and she is an Institute for Functional Medicine Certified Practitioner and the Medical Director of The UltraWellness Center. Dr. Boham lectures on a variety of topics, including Women's Health and Breast Cancer Prevention, insulin resistance, heart health, weight control and allergies. She is on the faculty for the Institute for Functional Medicine. Dr. Mark Pimentel is a Professor of Medicine and Gastroenterology through the Geffen School of Medicine and an Associate Professor of Medicine at Cedars-Sinai. Dr. Pimentel is also the Executive Director of the Medically Associated Science and Technology (MAST) program at Cedars-Sinai, an enterprise of physicians and researchers dedicated to the study of the gut microbiome in order to develop effective diagnostic tools and therapies to improve patient care.  Dr. Pimentel has over 150 publications in many high-profile journals, and he is the author of the book, The Microbiome Connection: Your Guide to IBS, SIBO, and low fermentation eating. This episode is brought to you by BIOptimizers. Head to bioptimizers.com/hyman and use code HYMAN10 to save 10%. Full-length episodes can be found here: Is Histamine Intolerance The Cause Of Your Mysterious Symptoms? What is Histamine Intolerance? Surprising Symptoms You Need to Know IBS: It's Not In Your Head—Advances In Diagnosing And Treating, Bloating And Tummy Troubles

Live Long and Master Aging
Fail, adapt, thrive for life | Prof. Manu Kapur

Live Long and Master Aging

Play Episode Listen Later Apr 16, 2025 29:52


In this episode we explore how the skills needed to live a longer healthier life can be honed through our own failures. Prof. Manu Kapur discusses the concept of 'productive failure' and how learning from our mistakes can lead to deeper understanding and personal growth. He shares his journey from aspiring soccer player to a researcher in learning sciences, discovering the importance of failure as a mechanism for learning.The conversation explores how these principles can be applied to health, fitness, and personal development, as well as the significance of setting realistic goals and learning from both personal and vicarious failures. Kapur also highlights the need for resilience in the face of unexpected setbacks and the importance of social connections in achieving long-term health and well-being.Kapur is a professor of Learning Sciences and Higher Education at ETH Zurich and the Director of the Singapore-ETH Center. PartiQlar supplementsEnhance your wellness journey with PartiQlar supplements. No magic formulas, just pure single ingredients, like NMN, L-Glutathione, Spermidine, Resveratrol, TMG and Quercetin. Get a 15% discount with the code MASTERAGING15 at PartiQlarSupport the showThe Live Long and Master Aging (LLAMA) podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice. If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.

Heal Thy Self with Dr. G
5 Natural Allergy Remedies That Actually Work (Backed by Science!) | #368

Heal Thy Self with Dr. G

Play Episode Listen Later Mar 31, 2025 18:48


In this video, Dr. G explores the alarming rise in allergies and offers natural solutions. Dr. G discusses the hygiene hypothesis – how overly clean environments weaken immune systems, leading to increased allergy and autoimmune disease risk. He highlights the dangers of conventional allergy medications and advocates for a holistic approach, emphasizing the importance of early childhood exposure to diverse environments and gut health. The video details five science-backed natural allergy remedies: quercetin, stinging nettle, butterbur, bromelain, and N-acetylcysteine, explaining their mechanisms of action and recommended dosages. #allergies #natural #wellness ==== Thank You To Our Sponsor! Jaspr Go to jaspr.co/DRG and use code DRG for $300 off for a limited time. ==== Timestamps: 00:00:00 - Allergies: Hygiene Hypothesis 05:07 - Immune System & Environment 06:23 - Air Quality & Home Health 09:26 - Quercetin & Nettle for Allergies 12:31 - Natural Allergy Remedies 15:40 - NAC, Allergies & Immunity Be sure to like and subscribe to #HealThySelf Hosted by Doctor Christian Gonzalez N.D. Follow Doctor G on Instagram @doctor.gonzalez https://www.instagram.com/doctor.gonzalez/

Live Long and Master Aging
Redefining healthy eating | Elizabeth Borelli

Live Long and Master Aging

Play Episode Listen Later Mar 21, 2025 35:39


How can a joyful and holistic approach to food help us to live longer and better?  Elizabeth Borelli is a lifestyle coach, nutrition expert and author of Tastes Like La Dolce Vita, where she shares her mission to help us live not only longer but better—enjoying a long healthspan, a life where we stay healthy, active, and mentally sharp well into our later years. Her work weaves together a passion for nutritious, satisfying food and practical wellness strategies inspired by Italy's famously healthy lifestyle. In this fun interview, Elizabeth shares insights that go beyond recipes, offering a holistic approach to well-being and vitality, through lifestyle adjustments, mindset shifts, or some of her favorite Mediterranean-inspired habits. PartiQlar supplementsEnhance your wellness journey with PartiQlar supplements. No magic formulas, just pure single ingredients, like NMN, L-Glutathione, Spermidine, Resveratrol, TMG and Quercetin. Get a 15% discount with the code MASTERAGING15 at PartiQlarSupport the showThe Live Long and Master Aging (LLAMA) podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice. If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.

Get Lean Eat Clean
Episode 438 - Natural Solutions for Seasonal Allergies

Get Lean Eat Clean

Play Episode Listen Later Mar 18, 2025 6:39


This week I discuss seasonal allergies and share the top eight natural remedies to manage them.I emphasize the importance of trial and error in finding what works best for individuals and provide practical tips for incorporating these remedies into daily routines.Here are the top 8 natural remedies I found through research:Nettle leaf tea can inhibit histamine production.Quercetin-rich foods can help stabilize mast cells.Nasal irrigation can significantly improve allergy symptoms.Probiotics are linked to better gut health and allergy relief.Butterbur may be as effective as antihistamines.Essential oils like eucalyptus can reduce congestion.Minimizing exposure to allergens is crucial.Spirulina has anti-inflammatory properties for allergies.Hopefully this helps combat the onset of seasonal allergies and allows you to enjoy being outdoors this spring!--If you love the Get Lean Eat Clean Podcast, we'd love for you to subscribe, rate, and give a review on Apple Podcasts and Spotify! Until next time!Links:Interested in Upgrading your Mitochondria, Improving Energy and Sleep! Check out Troscriptions: https://bit.ly/4ik5kK5Use Discount Code for 10% OFF: EATCLEAN----Watch Get Lean Eat Clean podcast video episodes on YouTube!YouTube.com/@briangryn3680-----How to Take Simple Steps to Reclaim the Body, Energy, and Strength You Had 10-15 Years Ago Using My Stepladder System:https://www.stepladdersystem.com/----B.rad Whey Protein Isolate Superfuel:The Best Protein on The Planet! Available in Two Delicious Flavors: Vanilla Bean and Cocoa BeanUse Coupon Code glec10off for 10% off your order!https://a.co/d/731gssV----My favorite health bars with clean ingredients!https://www.eatprima.com/BRIAN6816310% OFF with this link!| Listen to the Get Lean Eat Clean Podcast |►Apple Podcasts | https://podcasts.apple.com/us/podcast/get-lean-eat-clean/id1540391210►Spotify | https://open.spotify.com/show/0QmJzYZsdV6tUNbDxaPJjS| Connect with Brian |►Website | https://www.briangryn.com►Instagram | https://www.instagram.com/bdgryn►Facebook | https://www.facebook.com/getleanandeatclean►Twitter | https://twitter.com/grynnerwinner

Live Long and Master Aging
Stem cell therapy: Longevity's next frontier? | Dr. Joy Kong

Live Long and Master Aging

Play Episode Listen Later Mar 14, 2025 43:41


Stem cell therapy is a growing field of medical intervention that is being used to enhance longevity and healthspan.  Advancements in research, biotechnology, and regenerative medicine have expanded its potential applications but it also raises both ethical and efficacy concerns. The primary ethical issue comes from the use of human embryos, which some people believe is morally problematic. While many countries regulate or restrict their use, others allow research with oversight. In this interview with Dr. Joy Kong, a stem cell specialist at Chara Health Center in Los Angeles, we explore the practical aspects of treatment as well as the wider considerations surrounding stem cell sources, the long-term effects of therapy, and Dr. Kong's personal journey in regenerative medicine. PartiQlar supplementsEnhance your wellness journey with PartiQlar supplements. No magic formulas, just pure single ingredients, like NMN, L-Glutathione, Spermidine, Resveratrol, TMG and Quercetin. Get a 15% discount with the code MASTERAGING15 at PartiQlarSupport the showThe Live Long and Master Aging (LLAMA) podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice. If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.

Biohacking with Brittany
Q&A: My Upgraded Supplement Routine, Baby Acne Remedies That Actually Work, and the Best Immune Boosters for Kids

Biohacking with Brittany

Play Episode Listen Later Mar 7, 2025 47:05


I dive into another exciting Q&A session where I break down my current supplement routine, the best natural alternatives to oregano oil for kids, and how to safely treat baby acne.  I share my personal experiences, science-backed research, and practical tips for postpartum recovery, gut health, and longevity. Send me a DM on Instagram to get your questions answered! I TALK ABOUT:  03:20 – The full list of supplements I'm currently taking and why 04:40 – Postpartum recovery (Needed Prenatal code: BIOHACKINGBRITTANY; Green Pasture Cod liver oil; BiOptimizers Magnesium code: BIOHACKINGBRITTANY) 11:40 – Gut health microbiome optimization (TinyHealth code: BIOHACKINGBRITTANY; Pendulum Akkermansia; Seed; Florastor; BiOptimizers P3-OM, BiOptimizers Masszymes code: BIOHACKINGBRITTANY) 24:05 – Longevity and anti-aging (Fatty 15 code: BIOHACKINGBRITTANY; NOVOS Core and Boost code: BIOHACKINGBRITTANY) 32:50 – Managing inflammation naturally (Partiqlar - L-Glutathione, Resveratrol, Quercetin code: BIOHACKINGBRITTANY) 35:40 – Oregano oil is too strong for kids and alternatives 38:55 – Natural immune boosters for kids: (Gaia Elderberry syrup; Herb Farm garlic oil; ARMRA colostrum; Mary Ruth's probiotics; Evivo code: BIOHACKINGBRITTANY) 41:20 – Natural remedies for baby acne (breast milk, probiotics, and toxin-free detergent -Branch Basics, Molly Suds, Attitude, Mother Dirt AO+) SPONSORS: Optimize your cardiovascular health with science-backed supplements from Calroy Health Sciences for better circulation, heart function, and energy—save $50 on bundles using my link. Elevate your brainpower and energy with four powerful mushrooms in a delicious daily drink from BiOptimizers Mushroom Breakthrough —get 10% off with code BIOHACKINGBRITTANY. RESOURCES: Optimize your preconception health by joining my Baby Steps Course today! Optimize your preconception health and fertility through my free hormone balancing, fertility boosting chocolate recipe! Download it now! My Amazon storefront LET'S CONNECT: Instagram, TikTok, Facebook Shop my favorite health products Listen on Spotify, Apple Podcasts, YouTube Music

Intelligent Medicine
Leyla Weighs In: Honey Therapy--A Sweet Solution to Seasonal Allergies

Intelligent Medicine

Play Episode Listen Later Feb 28, 2025 23:40


Nutritionist Leyla Muedin discusses the potential benefits and considerations of using local raw honey as an immunotherapy for seasonal allergies and allergic rhinitis. Leyla explains how small amounts of local pollen in raw honey might help desensitize the immune system to allergens over time. She reviews various studies, highlighting both promising and inconclusive results, and cautions about the variability of pollen in honey and the risk of allergic reactions. Leyla also addresses the potential side effects of long-term antihistamine use, including an increased risk of dementia, and advocates for exploring natural alternatives. The episode is informative for individuals considering natural remedies and provides guidance on the safe use of honey for allergy relief.

Zestology: Live with energy, vitality and motivation
Is Quercetin a Biohacking Must-Have? (feat. Klaudia Balogh) #566

Zestology: Live with energy, vitality and motivation

Play Episode Listen Later Feb 3, 2025 31:19


Quercetin is having a moment, thanks to a viral discussion on Joe Rogan's podcast. But why? Is this now the new supplement that all self-respecting biohackers should be taking? Also today... the world's most expensive gym, has recently opened in Manhattan's West Village, targeting the super-rich who seek optimized health and fitness through biohacking. What they offer is pretty spectacular. But can we do the same on the cheap? Of course we can! (Sort of...) Follow Klaudia Balogh on Instagram. Join 30k+ weekly biohackers who receive the latest tech + techniques + reviews + insider biohacking news by signing up for the weekly newsletter here.   THIS SHOW IS BROUGHT TO YOU BY: Magnesium Breakthrough by BIOptimizers  Magnesium Breakthrough contains seven different forms of magnesium, each playing a unique role in your body. From improving sleep quality to enhancing brain function, and from boosting metabolism to balancing stress response, magnesium is involved in over 600 biochemical reactions. An epic supplement! Just go to bioptimizers.com/tony and use code TONY10 for 10% off. In the UK? Use the same discount code at https://bioptimizers.co.uk/.

Soaring Child: Thriving with ADHD
144: Bio Essentials for ADHD: A Favorite Supplement with Resveratrol, Quercetin, and Pterostilbene with Dana Kay

Soaring Child: Thriving with ADHD

Play Episode Listen Later Jan 30, 2025 14:27


Tune in to this episode of The Soaring Child Podcast, where Dana Kay, a board-certified holistic health and nutrition practitioner, explores the power of BioEssentials, a natural supplement designed to support children with ADHD. Combining the antioxidant and anti-inflammatory benefits of Resveratrol, Quercetin, and Pterostilbene, BioEssentials aims to enhance brain health, reduce inflammation, and improve focus. Listen now to discover the science behind these key ingredients, how they work together, and their potential to complement a healthy diet and lifestyle. Don't forget to grab your free supplement cheat sheet at the link below!  Links Mentioned in the Show:  My Favorite Place to buy Supplements - http://adhdthriveinstitute.com/supplements  Bio Essentials - https://shop.adhdthriveinstitute.com/bio-essentials.html  Bio Essentials Cheat Sheet - https://info.adhdthriveinstitute.com/supplement-for-bio-essentials    Links to Previous Episodes in this Supplements for ADHD Series: Magnesium -  https://adhdthriveinstitute.com/podcast/soaring-child-episode-93/  Saffron - https://adhdthriveinstitute.com/podcast/soaring-child-episode-136/  GABA - https://adhdthriveinstitute.com/podcast/soaring-child-episode-137/  L-Theanine -  https://adhdthriveinstitute.com/podcast/soaring-child-episode-142/  Key Takeaways: [3:27] Overview of Bio Essentials and Its Key Ingredients [5:15] How Bio Essentials Supports Brain Health and Cognitive Function [5:50] Pros of Bio Essentials for ADHD Management [9:26] Potential Drawbacks and Considerations [11:25] Natural Ways to Obtain the Ingredients in Bio Essentials Memorable Moments: "Our mission is to help families of children with ADHD thrive using natural strategies and practical solutions." "BioEssentials is a powerful combination of Resveratrol, Quercetin, and Pterostilbene designed to support focus, reduce inflammation, and protect brain health." "Inflammation in the body can mimic ADHD symptoms—even for people without ADHD." "You can't supplement your way out of a poor diet, but supplements like BioEssentials can be powerful tools in your toolbox." "This isn't about replacing medication, but finding complementary solutions that work with your child's unique needs." "Resveratrol, found in grapes, protects brain cells from oxidative stress and supports neurotransmitter balance." "Pterostilbene crosses the blood-brain barrier more effectively, enhancing its ability to promote cognitive function." "Small changes in diet or adding supplements like BioEssentials can make a big difference in reducing ADHD symptoms." "If we can reduce inflammation in the body, we can give our children a better chance to focus, regulate emotions, and thrive." "Always consult a healthcare provider before starting new supplements to ensure they align with your child's needs." Dana Kay Resources:

During the Break
The Power of Quercetin in Combatting Illness with The Holistic Navigator

During the Break

Play Episode Listen Later Jan 24, 2025 56:30


An episode from The Holistic Navigator. This is not to diagnosis or treat any disease or illness. Consult your physician before taking supplements or medications OR before you stop taking medications. This is for entertainment/informational purposes only-do your own research and talk to your doctor as needed! In light of a new variant and possible new waves of pandemic illness, we always want to be proactive and do what we can to provide information to help people combat illness naturally. We're thrilled to have Dr. Robert Rountree back on the show to walk us through his favorite supplements, backed by science of course, to help keep illness at bay. This episode is quite literally an A-Z look at what you need to give your body the best shot at staying well naturally. Meet Dr. Robert Rountree: On this week's episode we welcome back Dr. Robert Rountree to talk about his favorite supplements that EVERYONE should be taking to help combat illness. Dr. Rountree is a practicing physician out of Boulder, CO and is Chief Medical Officer for THORNE® and he breaks down the essential vitamins and nutrients he takes on a daily basis, gives suggestions for dosing, and even throws in a couple extra products that might not be on your radar. Some Points We Discuss: What nutrients should someone consider as they want to build their immune system? (5:53) What are some of the most important things to know about vitamin D supplementation? (21:03) What makes quercetin so unique for immune health? (40:24) Some Key Takeaways From This Episode: The alphabet list is not necessarily particular to any virus or illness. This is great for the immune system in general. (10:37) Always choose methylated B vitamins over folic acid. (16:59) There's a delayed effect with Vitamin D. You don't see the impact immediately. (26:44) Quercetin can stabilize immune cells and prevent the production of histamine. (41:25) This podcast is powered by ZenCast.fm

The TriDoc Podcast
Ep. 163: Quercetin/Luke Tasker

The TriDoc Podcast

Play Episode Listen Later Jan 24, 2025 64:45 Transcription Available


In this episode:Quercetin, a natural flavonoid, takes center stage in the Medical Mailbag as we dive into its potential benefits for preventing illness, especially during the cold and flu season. Jeff and Juliet explore the science behind quercetin's effectiveness, discussing various studies that highlight its role in supporting immune function for athletes and active individuals. The conversation shifts gears as I welcome Luke Tasker, a remarkable age group triathlete who has quickly risen through the ranks of the sport. Luke shares his unique journey from modern pentathlon to triathlon, detailing his training methods and the mindset that drives his success. With insights on goal-setting and overcoming challenges in competitive racing, this episode is packed with valuable takeaways for athletes of all levels.Segments:[06:12]- Medical Mailbag: Quercetin[32:15]- Interview: Luke Tasker Links@Taskertri on Instagram

Dr. Berg’s Healthy Keto and Intermittent Fasting Podcast
7 Foods to REVERSE Kidney Damage (Must Watch)

Dr. Berg’s Healthy Keto and Intermittent Fasting Podcast

Play Episode Listen Later Jan 6, 2025 6:59


Today, we're going to talk about kidney health. A big myth is that potassium is bad for the kidneys, but this isn't true! Our bodies require 4700 mg of potassium each day. The only time you'd want to avoid potassium is if you have advanced-stage kidney disease. Potassium protects kidney health in several ways. It helps lower high blood pressure, which damages the kidneys and protects against kidney stones. Too much sodium can be hard on the kidneys, but the remedy is more potassium. Many factors can contribute to kidney damage, including the following: •High sugar consumption •Alcohol •NSAIDs •Certain medications •Pesticides •Heavy metals •Food dyes •Phosphorus from soda A proper diet with adequate vitamin D, potassium, and magnesium can significantly improve kidney health. The following foods protect the kidneys from damage and support kidney health: 1. Vegetables: asparagus, celery, bell peppers, cabbage, cauliflower, garlic 2. Magnesium-rich foods: pumpkin seeds, leafy greens, avocadoes, magnesium glycinate 3. Probiotic-foods: kefir, yogurt, sauerkraut, kimchi 4. Moderate amounts of high-quality protein 5. High-antioxidant foods: strawberries, blueberries, blackberries, beets 6. Quercetin: onions 7. Extra virgin olive oil Consuming tea is a great way to stay hydrated and support kidney health. Polyphenols found in tea are very beneficial for the kidney. Green, nettle, dandelion, turmeric, and decaffeinated black tea are all great options. Frequent eating can overtax the kidneys' filtration system. A low-carb diet and intermittent fasting are very beneficial for kidney health. Intermittent fasting can decrease the stress on the kidneys and significantly reduce insulin. Too much insulin can be damaging to the kidneys. Recommended Olive Oil Link: https://sanmicheleorganic.com/product...

Intelligent Medicine
Q&A Special Edition: Inside Our Cabinets--The Supplements we Rely On, Part 1

Intelligent Medicine

Play Episode Listen Later Jan 2, 2025 29:19


In this special New Year's edition Q&A Dr. Ronald Hoffman and Nutritionist Leyla Muedin share their personal supplement regimens for 2025. They discuss the variety of supplements they take, including multivitamins, specific minerals, omega-3s, anti-inflammatories, probiotics, and immune-supportive nutrients. They also emphasize the importance of personalized nutrition and caution listeners against directly mirroring their supplement routines. The episode includes advice on seasonal adjustments to supplementation, the benefits of different nutrient combinations, and general tips for maintaining a balanced approach to supplement intake. Dr. Hoffman and Leyla also touch on their personal health goals and the rationale behind their choices, offering listeners insights into optimizing their own supplement strategies.

Dr. Berg’s Healthy Keto and Intermittent Fasting Podcast

DATA: https://pmc.ncbi.nlm.nih.gov/articles... The Most Powerful Antioxidant (Melatonin) ▶️ • The MOST POWERFUL Antioxidant Is Mela... Did you know that too much iron can decrease longevity? Your body makes hydrogen peroxide that is used by the immune system to kill microbes. When hydrogen peroxide combines with iron, it can cause serious cellular damage. People with iron-deficiency anemia often have dysfunctional iron, which means it's unavailable to the red blood cells. This could be why we are not seeing a decrease in anemia even though we've increased iron in the food supply. Iron overload may increase your risk for Alzheimer's, Parkinson's, cancer, heart disease, and more. Excess iron causes oxidative stress and increases inflammation. As we age, we naturally accumulate more iron. Around 70% of our iron is stored in protein in the blood that helps carry oxygen. Ferritin should be inside your tissues to protect you from free iron and control when iron is released. This very efficient system recycles iron in the body. Certain pathogens, microbes, and infections use iron as fuel. This is why the body protects free iron. Some people feel better after donating blood, indicating they have too much iron. Too much iron without enough copper is a big problem. If you think you have this problem, limit iron exposure before taking a copper supplement. Iron is found in enriched flours, grains, and refined carbohydrate products. Shellfish, organ meats, sunflower seeds, and dark chocolate are good sources of copper. To combat oxidative damage caused by iron and other factors like alcohol, smoking, pollution, and junk foods, you'll want to build up your antioxidant reserve. Glutamine found in red meat is vital, but protein is the most important! It's especially important to consume enough protein as you get older. Zinc, manganese, magnesium, and selenium can increase antioxidant networks to help you regulate excess iron. Quercetin, curcumin, black tea, and increasing melatonin are also very beneficial. Lactoferrin is the most powerful chelator for iron. It's found naturally in dairy and can be taken as a supplement.

Dr. Berg’s Healthy Keto and Intermittent Fasting Podcast
7 Foods You Should Be Eating After You Reach the Age of 50

Dr. Berg’s Healthy Keto and Intermittent Fasting Podcast

Play Episode Listen Later Nov 11, 2024 7:48


Today, I'm going to tell you about some important foods and nutrients that should be part of a healthy diet for people over 50. Dr. David Sinclair, an expert on longevity, has researched longevity genes called sirtuins. NAD can increase sirtuins! NAD is derived from niacin. It works inside your mitochondria, converting food to energy. As we age, our NAD decreases. Many people take supplements and get injections to boost NAD. Dr. Abram Hoffer wrote a book about the diseases caused by too little niacin and how many diseases can be cured with mega doses. He's one of the doctors who started the Orthomolecular Medicine Group, which used high doses of nutrients to create therapeutic dosages. The following foods can increase NAD and should be part of a healthy diet for people over 50: 1. Beef liver 2. Grass-fed red meat 3. Probiotic-rich foods—raw sauerkraut, yogurt 4. Parsley (celery or chamomile tea can also work) 5. Curcumin—turmeric 6. Quercetin—onions 7. Omega-3 fatty acids—wild-caught fatty fish, cod liver Sulforaphane, found in cruciferous vegetables, is also beneficial for healthy aging. Broccoli sprouts and radish sprouts are great to add to salads! Anthocyanins, found in blue and purple foods like blueberries, blackberries, and purple cabbage, are also good for anti-aging. Niacin: The Real Story BOOK LINK: https://www.amazon.com/Niacin-Story-W... A Plague of Corn BOOK LINK: https://www.amazon.com/Plague-Corn-So...

Dr. Berg’s Healthy Keto and Intermittent Fasting Podcast

There are many ways that vitamin D function supports cancer prevention. Vitamin D triggers a cell to commit suicide if it's damaged. It helps regulate cell growth and has potent anti-inflammatory properties. Vitamin D enhances almost every part of your immune system, enhances chemotherapy, and makes insulin more sensitive. It downgrades genes that cause cancer and supports the gut microbiome, which is 80% of your immune system. In a cancer cell, inflammation and a hypoxic, acidic environment block the absorption of vitamin D. Cancer also blocks the enzymes that allow you to convert inactive vitamin D to the active form. Cancer damages the liver and kidney, two significant sites of vitamin D metabolism. Around 80% of tumors produce a hormone similar to the parathyroid hormone, which extracts calcium from our bones. This is why hypercalcemia is a side effect of cancer. When the parathyroid hormone goes up, it lowers and inhibits vitamin D. Too much calcium in the blood also inhibits vitamin D. There are two systems of vitamin D: one that affects bone and calcium, and the other that supports the immune system. The bone system only requires a small amount of vitamin D every two weeks, while the other requires higher amounts daily. When dealing with cancer, consider taking around 50,000 IU of vitamin D with magnesium, vitamin K2, and zinc daily. The World Health Organization acknowledges that vitamin D has anticarcinogenic properties. Autoimmune conditions, osteoarthritis, tuberculosis, and HIV are also associated with vitamin D deficiency. Along with increasing vitamin D3, the following epigenetic factors can help with cancer prevention: 1. Magnesium 2. Omega-3 fatty acids 3. Resveratrol 4. Quercetin 5. Curcumin 6. Berberine 7. Intense exercise 8. Sulforaphane 9. Ginger 10. Fasting 11. Low-carb diet 12. Probiotics 13. Infrared light 14. Decreasing stress DATA: https://orthomolecular.activehosted.c... https://www.mdpi.com/2076-3417/10/12/...