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Diets rich in fruits and vegetables preserve brain function—but in vulnerable persons with the ApoE4 “Alzheimer's gene”, more meat staves off decline, contradicting years of recommendations to minimize animal protein; Supplements for adrenal insufficiency; “Forever chemicals” may weaken teen's bones—but menopausal hormone replacement therapy decisively fends off osteoporosis; Legionnaire's disease strikes poor and affluent alike in New York City; Doctors propose warning labels for GLP-1 drugs on account of this under-appreciated danger.
Pentagon plans widespread testosterone screening for troops; New study claims arthroscopic surgery for age-related degenerative changes of knees is worthless; Widely touted “precision” proton therapy doesn't outperform conventional radiation treatment for prostate cancer; Comparing the effectiveness of gummies and liquids vs. tablet or capsule forms of supplements; Supplements to lower LDL; Lithium orotate for Alzheimer's prevention; Novel ultrasound treatment may target inflammation in osteoarthritis; Researchers explore antiviral treatments for multiple sclerosis.
Vitamin B12 Deficiency--The “Aging” Symptoms You Shouldn't Ignore: Leyla Muedin, a registered dietitian nutritionist in New York City, discusses vitamin B12 deficiency as a common problem that can mimic normal aging, noting adults need only about two micrograms daily to support red blood cells, nerves, and DNA. She reviews the history of liver treatment for pernicious anemia and explains that deficiency remains common in older adults, vegans/vegetarians, and people with impaired absorption due to low stomach acid, autoimmune gastritis, weight loss surgery, or medications such as metformin and proton pump inhibitors. Symptoms can develop slowly and include fatigue, weakness, shortness of breath, numbness/tingling, poor balance, memory issues, and brain fog; she advises medical evaluation and B12 testing rather than assuming aging or relying on wellness-clinic injections when levels are normal. She emphasizes B12 is primarily in animal foods, so vegans need supplements, and notes broader nutrient shortfalls she sees in vegan clients.
Many U.S. states require HBV, blood testing, and vitamin K shots at, or soon after, birth. While these interventions may appear helpful. hospitals often provide no informed consent. They also neglect to inform parents they have a right to opt out, with some states going to lengths in order to conceal such opt-out forms. Some states lie about the procedures to coerce compliance. Medical staff are not above threatening to call police or CPS on parents, or prevent them from leaving the hospital, or conceal the baby until they acquiesce. In these cases, they are guilty of kidnapping and violating federal law. As for vitamin k, the shots actually have far more ingredients, some of which are known to kill infants according to the CDC. As for blood testing, most states store the blood without parental consent and give it to the military or private companies. *The is the FREE archive, which includes advertisements. If you want an ad-free experience, subscribe below.
Does coffee really dehydrate you? A deeper dive on this important topicHelp for nighttime urinationPlease discuss aortic dissection
How do I find a preventive cardiologist in northern New Jersey?What is the best supplement for dissolving bone spurs?What is the half-life of vitamin D, either by supplement or sun exposure?What do you think about mushroom coffee? Does it have any health benefits?Please discuss how strontium affects DEXA scan results
Darchei Emori & Alternative Medicine - Document for Daf 77 by Simon Wolf
In this episode, we explore what the CANMAT guidelines say about complementary and alternative medicine (CAM) for depression — from St. John's wort to saffron — and how to have evidence-based, collaborative conversations with patients who prefer a more natural approach to treatment. Faculty: Sagar V. Parikh, M.D., F.R.C.P.C. Host: Richard Seeber, M.D. Learn more about our memberships here Earn 1.25 CME: Rethinking Depression Treatment: An Update of CANMAT's Guidelines Complementary and Alternative Medicine for Depression: CANMAT Recommendations
Dr. David Chernoff, Chief Medical Officer of Setpoint Medical, discusses electrically driven vagus nerve stimulation (VNS) as a “neuroimmune modulation” approach to autoimmune and inflammatory disease. Chernoff explains the vagus nerve's sensory role in monitoring organs and signaling the brainstem and spleen to regulate immune responses, and how precise stimulation can reduce pro-inflammatory cytokines without immunosuppression. Setpoint's miniaturized, wireless, MRI-compatible implant is placed in an outpatient 45-minute neck procedure and delivers one minute of daily stimulation titrated to an upper comfort level; long-term safety is supported by prior surgical experience and a 242-patient blinded RA study with two-year data, leading to FDA approval for rheumatoid arthritis. The discussion covers add-on use with medications, potential steroid tapering, reimbursement, and research in Crohn's disease, relapsing MS (vision and remyelination), and other conditions, including psoriatic arthritis, lupus, and neurodegenerative diseases.
Dr. Hoffman continues his conversation with Dr. David Chernoff, Chief Medical Officer of Setpoint Medical.
When filmmaker and homeopath Ananda More first encountered homeopathy, she dismissed it as pseudoscience. It wasn't until an unexpected experience while traveling through India that her certainty began to unravel. Years later—even after becoming a practicing homeopath herself—she still wrestled with the question: "is this all simply placebo?" That honest skepticism became the foundation for Magic Pills, a documentary exploring the science, stories, politics, and controversy surrounding one of the world's most debated healing modalities.In this conversation, we go far beyond the basics of homeopathy. We explore the difference between healthy skepticism and dogma, why homeopathy provokes such intense resistance, the state of the scientific research, censorship within medicine and media, energetic healing, placebo, consciousness, and what it means to follow evidence wherever it leads.Ananda also shares remarkable patient stories, discusses the global effort to preserve access to homeopathy, and explains why empowering parents with safe, non-toxic tools may be one of the most important investments we can make in future generations. Whether you're completely new to homeopathy or have questioned it for years, this conversation is an invitation to look deeper before deciding what to believe.Learn more about Ananda and her work:
Mushrooms for Sleep and Cognitive Support: Jim LaValle, a clinical pharmacist, author, and board-certified clinical nutritionist, details Wakunaga/Kyolic's new Specialty Series mushroom products and related health strategies. He reveals a sleep formula with reishi, L-theanine, valerian, and Aged Garlic Extract aimed at calming stress and supporting better sleep. The formula for cognition includes lion's mane for memory support and aronia berry antioxidants. He also emphasizes Aged Garlic Extract's heart benefits.
Dr. Hoffman continues his conversation Jim LaValle, a clinical pharmacist, author, and board-certified clinical nutritionist.
Homes That Heal | Transform Your Home Into a Health and Wellness Sanctuary
Ep 109 | If you've ever typed "what size infrared sauna do I need" into a search bar, gotten lost in a Facebook sauna group rabbit hole, or you're wondering what to expect once you start using your sauna—this episode is for you.In this Ask Jen episode, Jen answers three of the most common infrared sauna questions she gets every single day: how to choose the right sauna size for your home, the real difference between near, mid, and far infrared (and whether full spectrum is actually worth it), and what to realistically expect in your first 30 days of consistent sauna use. No analysis paralysis. No opinion spiral. Just straight answers from someone who's been in the infrared sauna space for over 15 years.
Carnitine, with acknowledged muscle and brain benefits, may find a new role in supporting cancer immunity; Calcium and vitamin D's bone-building impact may be limited; Internal visceral fat may accelerate brain aging, MRI study finds; The remarkable benefits of a newly-discovered mitochondrial booster—urolithin A (Mitopure®️).
Is it safe to stop statins “cold turkey”? Can the supplement ingredient HMB counteract age-related muscle loss? Researchers may have discovered the key to development of a true fat-burning weight loss medication; Can a mammogram yield clues about cardiovascular risk? Their bottom line threatened by GLP-1 weight loss drugs, BIg Food tweaks portion sizes, adds spices and flavorings to pique blunted appetites; Vitamins A & D may improve lung health for asthma sufferers; When it comes to thyroid medication prescribing, treat the numbers or treat the patient?
Registered dietitian Leyla Muedin discusses a Frontiers in Microbiology paper suggesting certain probiotics may help sequester heavy metals. The study, sponsored by the Italian company Probiotical and conducted with University of Ghent and University of Piedmont Orientale, researchers used in vitro testing and the SHIME gut simulator to assess Lactiplantibacillus plantarum, Lactobacillus crispatus, and Lactobacillus acidophilus against cadmium, lead, chromium, and mercury. L. plantarum and L. crispatus reduced metal bioavailability primarily in the simulated colonic phase, while L. acidophilus showed minimal detoxification; mercury was least reduced (~10%). An ex vivo mouse-intestine system found probiotic pre-incubation of metals preserved epithelial integrity and reduced inflammatory responses. Leyla notes limitations: corporate funding, only three strains tested, and no in vivo or human trials, though the findings support further animal and clinical research.
Some Americans are panicking at the recent so-called outbreak of "explosive diarrhea." The news is reporting hundreds of cases nationwide. But according to the AAFP, "acute diarrheal disease accounts for 179 million outpatient visits annually in the United States." So there is no sudden outbreak of disease, and the suppose culprit, the Cyclospora parasite, is only suspected but not proven to have caused the diarrhea. Strangely, a Meta data center recently dumped contaminated water into public sewers, spreading what they said was Cupriavidus gilardii, which can also cause diarrhea. Taco Bell, famous for its diarrhea aftereffects, has begun removing certain vegetables from their menu since produce is being blamed for the so-called outbreak. Whatever truth there may be to this should be overshadowed by the fact that produce is only contaminated because large scale in industrial farms often are polluted by animal agriculture, or animal feces is sprayed directly on the produce via collected water. Is it possible that this diarrhea is simply a byproduct of the poor American diet, severely deficient in fiber and burdened by excess protein. Both of these problems can separately cause diarrhea, but together are certainly essential cause. Other developed countries have a third the number of annual U.S. diarrhea cases. So what is happening?https://www.usatoday.com/story/graphics/2026/07/09/maps-explosive-diarrhea-outbreak-cyclosporiasis/90862952007/https://apnews.com/article/cyclospora-outbreak-michigan-31e5e0034d39e85c844065a2bd593ecbhttps://www.aafp.org/afp/2022/0700/acute-diarrheahttps://www.theguardian.com/us-news/2026/jul/08/meta-datacenter-ai-wyoming-waterhttps://nypost.com/2026/07/09/lifestyle/taco-bell-pulls-ingredients-off-menu-as-explosive-diarrhea-parasite-cases-surge/?sr_share=facebook&utm_source=facebook&utm_campaign=nypost&utm_medium=social&fbclid=IwY2xjawS9E9xleHRuA2FlbQIxMABicmlkETJuVDdFSUFWME1HWXF4U1dNc3J0YwZhcHBfaWQQMjIyMDM5MTc4ODIwMDg5MgABHsE7Yg3iMVCLTmtIsf61LLM61x7QdmHwTLcDJjgZAG8eO4DkhF4mKH38-64b_aem_YV9NJe_qxxvUnK9FraFLbQ*The is the FREE archive, which includes advertisements. If you want an ad-free experience, subscribe below.
Which is more effective, vitamin K2 or K4?How long can I take L-tryptophan as a sleep aid? What about 5-HTP?Is there any remedy for frequent nighttime urination?What are some suitable supplements I can take for exercise recovery?
Dealing with the heat - Europeans' disdain for air conditioningI have scaly and bumpy areas on my scalp that itch!Did homeopathic human growth hormone increase my cholesterol?
Dr. Hoffman continues his conversation with Dr. Austin Perlmutter, chief science officer of Big Bold Health.
Immune Regulation, Omega-3 Nuance, and Himalayan Tartary Buckwheat with Dr. Austin Perlmutter, chief science officer of Big Bold Health. He details immune regulation as a nuanced, multidimensional system shaped by diet and lifestyle rather than simple “boosting.” Perlmutter explains Big Bold Health's focus on immunometabolism, educating about immune complexity, and conducting studies on nutraceuticals, including use of CGMs and clinical trials. He discusses why eating fish often outperforms refined fish-oil supplements, noting conventional processing (heat, bleaching, deodorizing, esterification) and loss of other lipids and nutrients. Perlmutter highlights specialized pro-resolving mediators (resolvins, protectins, maresins) and vitamins A and D as potentially better preserved in minimally processed oils, and reviews typical omega-3 intake and target ranges. The conversation also covers immunosenescence/inflammaging and Big Bold Health research on sprouted Himalayan Tartary Buckwheat, its high polyphenols (rutin, quercetin), microbiome effects, and studies including epigenetic aging clocks and brain outcomes.
AI and Generative Biology: Authoring Life, Redesigning Healthcare, and Building Guardrails: Physician and molecular biologist Dr. Adrian Woolfson, co-founder of Genyro, a biotechnology company specializing in synthetic genome design and construction, and author of “On the Future of Species: Authoring Life by Means of Artificial Biological Intelligence,” discusses the convergence of AI with synthetic/generative biology that could make biology programmable and enable genome design and construction beyond traditional gene editing. Woolfson argues that the technology is morally neutral but is arriving rapidly and requires public awareness, governance, and guardrails due to risks, including misuse by authoritarian regimes and biological warfare. He discusses evolution's trade-offs and why he favors limiting human applications to curing disease and extending healthy longevity, while opposing germline modification; he explains germline vs somatic editing and cites the flawed, unethical case of a Chinese scientist attempting inherited HIV resistance. They examine sickle cell disease cures costing $2–$3 million, scalability issues, and trade-offs like malaria protection, and highlight non-medical benefits such as engineered crops, biomaterials, desalination, and DNA-based information storage.
Dr. Hoffman continues his conversation with physician and molecular biologist Dr. Adrian Woolfson, co-founder of Genyro, a biotechnology company specializing in synthetic genome design and construction, and author of “On the Future of Species: Authoring Life by Means of Artificial Biological Intelligence.”
Homes That Heal | Transform Your Home Into a Health and Wellness Sanctuary
Ep 108 | If you've been doing everything "right" and still feel exhausted by noon, this episode is going to make a lot of things click.Jenn Trepeck is a Health and Lifestyle Coach, podcaster, and author who's spent nearly two decades helping people cut through the noise and get back to what the body actually needs. In this episode, we dig into how to eat for energy and metabolic health—not another list of foods to avoid, but the simple shifts in how you eat that can change everything. We talk adrenal fatigue, cortisol, the protein and fiber framework Jenn teaches every client, and her Bullseye of Change method for making healthy habits actually stick.In this episode:[9:05] – Why it's not what you eat—it's how you eat[11:45] – Protein and fiber at every meal: what that actually looks like[20:37] – Brain fog, cortisol, and why stress may be driving your perimenopausal symptoms[25:35] – The real reason you're wired but tired (hint: it's your cortisol curve)[31:20] – Why biohacks don't work when the basics aren't in place first[34:35] – The Bullseye of Change: behaviors, habits, identity, and environment[39:20] – How to stay consistent with healthy eating when your environment changesIf you've been chasing answers in all the wrong places, this one brings it back to basics—and makes it feel doable.✨ This episode is for you if:You're exhausted by midday even after a full night's sleepYou've tried every diet and nothing seems to stick long-termYou want to support your metabolic health without obsessing over foodYou're curious about adrenal fatigue and what your cortisol is actually doingYou already know what to eat—you just can't make it stickMeet Jenn Trepeck:Jenn Trepeck has been described as a "force of nature" in the wellness space—and honestly, that tracks. She's a Health and Lifestyle Coach, podcaster, and consultant who grew up the skinny one in a family of dieters, spent years on the weight roller coaster, and eventually found her way out by learning the nutrition basics we're all supposed to know but nobody ever actually taught us. That shift changed her life, and she's been helping others do the same ever since. She's the host of the Salad with a Side of Fries podcast and author of Uncomplicating Wellness: Ditch the Rules. Quiet the Noise. Reclaim Your Life. (October 2025). Recognition includes Podcast Magazine's 40 under 40, the 2022 International Women's Podcast Award nomination for Visionary Leadership, the 2025 Women Who Podcast Award for Stellar Interview, and Ear Worthy's Best Health Podcast for both 2024 and 2025.
Europeans swelter through historic heat wave—but many resist air conditioning due to ingrained cultural attitudes; Break a sweat to beat the heat; Evidence that aged garlic extract curbs atherosclerosis risk; How to stave off age-related muscle atrophy; Probiotic-infused underwear to nourish the skin microbiome? Niacin augments glioblastoma treatment; Creatine for depression.
Melatonin can reduce chronic pain; Ultra-processed foods are becoming a worldwide scourge; Do biopsies spread cancer? Sauna benefits for staving off dementia; What may cause blood sugars to deteriorate in a heretofore well-controlled diabetic? Causes of excessive sleepiness.
Guest: Dr. Yi Song, Pathologist, Traditional Chinese Medicine Practitioner, and Author of The Regeneration Effect Is it possible to slow down the clock and heal chronic joint pain without relying on invasive surgeries? In this episode of The Better Life, host Dr. Pinkston sits down with Dr. Yi Song to explore the groundbreaking intersection of cutting-edge Western regenerative medicine and ancient Eastern philosophy. Dr. Yi Song shares his personal and professional journey into umbilical cord mesenchymal stem cell therapy—demystifying common misconceptions, explaining how these cells act as "medicinal signaling molecules" to jumpstart the body's natural repair systems, and detailing how he used these therapies to save his own mother from a looming amputation. Dr. Pinkston and Dr. Yi Song dive deep into the limitations of purely "evidence-based" Western medicine when it comes to intuitive healing, the critical importance of evaluating a patient's unique body constitution, and why traditional fundamentals—like diet, sleep, and emotional stress management—are non-negotiable for any therapy to truly succeed. Tune in to learn how to view your body as a garden, address the root causes of chronic inflammation, and take your first steps toward vibrant longevity. Key Takeaways from This Episode: The Signaling Power of Stem Cells: Why mesenchymal stem cells don't just grow into new tissue, but actually signal your own body to heal itself. Debunking the Myths: Clarifying the ethical, legitimate sources of modern stem cell therapies. Early Prevention vs. Crisis Management: Why you shouldn't wait until "the fire has already started" to address cellular exhaustion and aging. The Six Principles of Natural Longevity: A sneak peek into Dr. Yi Song's upcoming book, Regeneration Effect: Secret Wisdom for Staying Young. Connect with Our Guest: Websites: regenerationeffect.com | stemcelltherapyexperts.com Pre-Order the Book: book.regenerationeffect.com Free Gift (Tend Your Body Like a Garden): gift.regenerationeffect.com Podcasts: Regeneration Effect and Stem Cell Talk (Available on all major platforms) See omnystudio.com/listener for privacy information.
Bone Health Beyond Calcium: Vitamin D, K, Protein, Medications, and Metabolic Risks: Registered dietitian nutritionist Leyla Muedin discusses factors affecting bone health, osteopenia/osteoporosis, and limitations of bone mineral density as a measure of bone strength. She emphasizes optimizing vitamin D via 25-hydroxy D testing (aiming roughly 55–85 and avoiding over 100), ensuring vitamin K for proper calcium placement, and addressing malabsorption from GI conditions, food intolerances, or inflammation. She notes long-term proton pump inhibitor use can impair calcium and magnesium absorption and increase osteoporosis risk. Diet considerations include avoiding overly grain-heavy, acid-forming patterns and ensuring high biological value protein; she also mentions heavy metals affecting bones. Additional assessment includes magnesium and DHEA sulfate, plus resistance and balance training (ideally three times weekly). She highlights research linking hyperinsulinemia/type 2 diabetes/cardiovascular disease to fragility fractures despite normal or higher bone density, proposing carbohydrate restriction, fasting, and ketosis to improve bone remodeling via osteocalcin and mitochondrial function.
What happens when no one can explain your illness?
Carnivore diet controversiesWhat is a normal oxygen saturation? Mine has been 92-93 lately? Is that okay?
I've worked for many years on my feet and had surgery on both knees. How much glucosamine should I take?Can you discuss oral vs. IV chelation? How do you determine which is appropriate?How important is nitric oxide, and how can I increase mine?Are there any supplements I should stop taking before getting blood tests?
Cardiovascular Protection Beyond Statins--Nattokinase, Vitamin K2 MK-7, and Clinical Cardio Six: Neil Levin of NOW Foods/Protocol for Life Balance details cardiovascular protection beyond cholesterol-lowering drugs, emphasizing nutrient sufficiency, therapeutic “nutraceutical” dosing, and physician partnership with testing. They discuss nattokinase from fermented natto (typical 2,000 fibrinolytic units/day), describing research on reduced fibrinogen, improved blood viscosity and microcirculation, blood-pressure normalization, and higher-dose data suggesting benefits for arterial thickness and lipids without excessive blood-thinning. They review vitamin K: K1 for normal coagulation (risk with Coumadin relates to day-to-day variability) and K2 for calcium metabolism, highlighting MK-7's longer half-life and potency versus MK-4 and recommending pairing K2 with vitamin D. Levin outlines PFLB Clinical Cardio Six (D3, L-carnitine, hawthorn leaf/flower, solubilized grape seed extract, CoQ10, MK-7), ingredient sourcing/testing, omega-3 benefits, red yeast rice context, and controversy around vitamin E meta-analyses.
Dr. Hoffman continues his conversation with Neil Levin, the Senior Nutrition Education Manager and a product formulator for NOW(r) Foods and Protocol for Life Balance.
Cannabis has become one of the most polarizing plants in modern history, but hemp may be the more important story.In this episode, Ben and Mike sit down with Florida cannabis cultivators Anya and Jacob Smith of Green Smith Family Farms to explore the remarkable versatility of hemp and why so much of its history has been forgotten. The conversation moves well beyond CBD and THC into living soil, terpene diversity, clean cultivation, and why the health of the growing environment may directly influence the quality of the medicine it produces.Along the way, they discuss hemp's potential to replace plastics, produce cleaner building materials, improve agriculture, fuel engines, and even reshape entire industries. They also share practical guidance for finding high-quality CBD, explain why many experienced cannabis users naturally gravitate toward lower-THC products over time, and reveal a simple tip that can completely change the experience for anyone who has ever overdone THC.If terrain is the sum of the conditions that support life, then hemp deserves a much larger place in that conversation than it currently occupies. This episode explores why.Follow Anya and Jacob on Instagram at https://www.instagram.com/greensmithfamilyfarms/ or send Jacob an email at jacob@thehempcorp.net.Support Terrain Theory on Patreon! Our member platform gives you access to weekly bonus episode content. Check it out: https://www.patreon.com/TerrainTheoryExplore our growing list of intentional Terrain Support products at https://www.terraintheory.net/collections/terrainsupportTerrain Theory episodes are not to be taken as medical advice.If you have a Terrain Transformation story you would like to share, email us at ben@terraintheory.net.Learn more at www.terraintheory.netFollow Terrain Theory:Instagram: https://www.instagram.com/terrain_theory/Facebook: https://www.facebook.com/Terrain-TheoryX: https://twitter.com/terraintheory1YouTube: https://www.youtube.com/@terraintheoryMusic by Chris MerendaAfterParty music by Brendan Daniel
My new favorite woman Sara Foster is here, and we get real about everything: growing up in Hollywood with David Foster as her dad, our Brody Jenner connection, therapy, low self-esteem, dating after a 20-year relationship, and why she currently has zero interest in compromising for a man. We also talk about building an empire with Erin Foster — from Nobody Wants This to Favorite Daughter — plus the reality of rejection in Hollywood, hustle culture, and why not every woman needs to start a business.A word from my sponsors:Foria: Experience your juiciest and deepest sensual experience with a bottle of Foria. Foria is offering a special deal for our listeners. Get 20% off your first order by visiting https://foriawellness.com/HONEST OR use code HONEST at checkout. Lululemon: Go to https://lululemon.com right now. New styles drop all the time and the colors go fast, so don't wait. And if something doesn't work for you, free returns, always.Wayfair: Get prepped for patio season for way less. Head to https://Wayfair.com right now to shop all things home.K18: Shop at Sephora or get 10% off your first purchase at https://k18hair.com with code KRISTIN.Figs: Get 15% off your first order at https://wearfigs.com with the code FIGSRXCookUnity: Go to http://cookunity.com/HONEST or enter code HONEST before checkout for 50% off your first week.JS Health: https://www.jshealthvitamins.com code HONEST for 15% off your order at checkout.JSHealth Vitamins Berberine+ Clinical Trial† †Individual results may vary. Citruslabs Research Team, 2025, “A Clinical Trial to Evaluate the Effects of a Supplement to Support Blood Sugar Levels, Weight Management, and Other Related Outcomes." These trials were conducted on JSHealth Vitamins USA Berberine+ Formula. Formula may vary by region. Berbevis® for 4x better absorption than standard berberine^. ^Petrangolini, G., Corti, F., Ronchi, M., Arnoldi, L., Allegrini, P. & Riva, A., 2021. Development of an innovative berberine food-grade formulation with an ameliorated absorption: in vitro evidence confirmed by healthy human volunteers pharmacokinetic study. Evidence-Based Complementary and Alternative Medicine 2021:7563889. Available at: https://onlinelibrary.wiley.com/doi/10.1155/2021/7563889*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any diseaseFor more Let's Be Honest, follow along at:@kristincavallari on Instagram@kristincavallari and @dearmedia on TikTokLet's Be Honest with Kristin Cavallari on YouTubeProduced by Dear Media.This episode may contain paid endorsements and advertisements for products and services. Individuals on the show may have a direct or indirect financial interest in products, or services referred to in this episode.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Urolithin A (Mitopure) and Mitochondrial Renewal--Muscle, Immune, and Skin Benefits: Jen Scheinman, MS, RDN, CDN, Director of Science Communications at Timeline details urolithin A and Timeline's branded supplement Mitopure. She describes urolithin A's discovery through pomegranate research and worm studies showing a 45% lifespan increase. She discusses human research including improved walking distance and clinical outcomes in muscle endurance and strength. Urolithin A is presented as supporting mitochondrial health by promoting mitophagy—recycling damaged mitochondria—distinct from other mitochondrial supports like CoQ10 and NAD precursors. They explain most people cannot produce enough urolithin A from foods because only 30–40% convert precursors via the microbiome and it would require about six cups of pomegranate juice daily. Dosing discussed is 500–1,000 mg/day via gummies, capsules, or powder, with effects developing over months. She reviews emerging research on immune aging, preclinical work on brain and neurodegenerative conditions, and topical urolithin A for skin.
Dr. Hoffman continues his conversation with Jen Scheinman, MS, RDN, CDN, Director of Science Communications at Timeline.
Homes That Heal | Transform Your Home Into a Health and Wellness Sanctuary
Ep 107 | JD Tremblay sold his house to chase a finish line, slept in his car for over a year, and became one of only three people in the world to complete the EpicDeca. It took his nervous system completely shutting down for him to understand what real recovery requires.In this episode, Jen sits down with ultra-endurance athlete and certified naturopath practitioner JD Tremblay to talk about nervous system regulation, burnout recovery, and the connection between your home environment and your ability to truly heal. JD shares what years of extreme physical performance taught him about rest, resilience, and rebuilding a nervous system that had run him into the ground.✨ This episode is for you if:You've been running on empty and calling it normalYou're a high achiever who struggles to restYou've ever felt physically "fine" but completely disconnected from your bodyYou're curious how nervous system regulation supports long-term healingYou want to understand burnout recovery from someone who's lived through the extreme end of it
CBD may slow Alzheimer's progression by tamping down brain inflammation; Fifty million dollar settlement in Gardasil Classic action; Urethral stricture as a side effect of ablation for enlarged prostate; Zero-sugar diet may have unanticipated adverse health consequences; Are there drug-free alternatives for atrial fibrillation? Can you reverse lactose intolerance with a skin patch?
“The quick and the dead”: 80+ “Supermovers” show slowed cognitive decline; Dietary polyphenols help overcome vascular effects of prolonged sitting; Pros and cons of ketamine therapy for depression; Time-restricted eating alters microbiome to promote weight loss; Magnesium—what research reveals about better sleep, stress resilience, and whole-body wellness.
Vitamin K2 (MK-7) and Coronary Artery Calcification: Insights from a 2-Year Trial: Nutritionist Leyla Muedin discusses a two-year randomized clinical trial in JAMA Cardiology from Maastricht University Medical Center reporting that daily vitamin K2 (menaquinone-7, MK-7) at 360 mcg slowed progression of coronary artery calcification (CAC) in 180 patients with confirmed atherosclerotic cardiovascular disease and baseline CAC 50–400 Agatston units. Compared with placebo, consistent MK-7 use was associated with 29% lower CAC progression and 42% less arterial calcium mass progression, though CAC still increased in both groups; stenosis increases were numerically lower with MK-7 but not statistically significant. Leyla notes many participants were on statins and were smokers, highlighting that statins can raise CAC by stabilizing soft plaque via calcification. The trial suggests MK-7 may slow calcification in newer plaques, may improve arterial elasticity via matrix GLA protein activation, is inexpensive and safe, but clinical event reduction remains unproven; Leyla suggests considering MK-7 (possibly 360 mcg) with vitamin D, magnesium, and dietary measures.
I'm 78 and had a hysterectomy. Is it safe for me to eat tofu or other soy foods?Mitopure joins L'Oreal to create a face cream with Urolithin A.Does taking hyaluronic acid orally cause water retention?Can you discuss ETA contained in New Zealand green mussels?What are your thoughts on using vibration devices to help osteoporosis?
World Cup!What did humans eat from the Ice Age to the Bronze Age?What supplements should I avoid while undergoing radiation therapy for prostate cancer?What is the treatment for sarcoidosis of the lung? Both my friend and his wife have it.
Dr. Hoffman continues his conversation with Nathan Jones, founder and CEO of Xlear, Inc.
Nathan Jones, founder and CEO of Xlear, Inc., reveals xylitol's role in supporting oral and nasal “gateway” microbiomes by selectively starving acid-producing Strep mutans rather than indiscriminately killing bacteria, and warns that harsh mouthwashes can disrupt beneficial oral bacteria linked to nitric oxide production and possibly blood pressure. Jones outlines Spry and Xlear products (gum, mints, toothpaste, mouthwash, dry-mouth “Rain,” and upcoming gummy candies, a new dental probiotic with added nutrients, and a direct-to-consumer oral bacteria test kit with pre/post tracking). He discusses diet, emphasizing sugar as a key driver of cavities and criticizing limited focus on sugar in a Surgeon General oral health report. In part two, Jones describes ongoing and planned legal actions against the FTC over shifting evidentiary standards and reputational damage, then reviews Xlear's allergy and respiratory approach via nasal hygiene, product tiers (regular, Max with quercetin, Rescue botanicals, and a decongestant), and a forthcoming ectoine-based spray to support mucus barrier integrity.
Nitric Oxide Explained: Vascular Health, Exercise Performance, and N1o1 with Dr. Nathan Bryan, international Leader in Molecular Medicine, the first to describe nitrite and nitrate as indispensable nutrients required for optimal cardiovascular health. He details NO as a ubiquitous messenger affecting blood flow, erectile function, cognition, exercise performance, endothelial dysfunction, and aging-related declines in NO production. Bryan explains why PDE5 inhibitors like Viagra prolong cyclic GMP signaling but don't fix NO deficiency, and why beet products often fail due to variable nitrate content and inadequate dosing. He outlines his NO lozenge approach that generates NO gas from sodium nitrite and magnesium ascorbate, plus a fermented beet powder drink (NOBeets), and emphasizes the role of oral bacteria (and harms of antiseptic mouthwash/fluoride) in nitrate conversion. They review published endpoints, including flow-mediated dilation, blood pressure effects, inflammation markers, triglycerides, stem cells, plaque regression, applications to Alzheimer's, glaucoma/microvascular disease, safety/dosing considerations, risks of arginine supplementation, and a dual-chamber topical NO serum developed from wound-healing experience.
Dr. Hoffman continues his conversation with Dr. Nathan Bryan, international Leader in Molecular Medicine, the first to describe nitrite and nitrate as indispensable nutrients required for optimal cardiovascular health.
Why aren't there more medical insurance plans that cover alternative medicine? Solutions for Long Covid; MK7 vitamin K slows arterial calcification; Keto diet shows promise for treatment of anorexia; It's not so much salt restriction—it's the dietary sodium/potassium ratio in hypertension; Study finds multivitamins don't keep you from getting Covid—but when you get it, it's milder; Incidence of social anxiety disorder is soaring among young people.