POPULARITY
Welcome to the Transatlantic series, a co-production of Audible Bleeding (a publication of the SVS) and the ESVS podcast. In today's episode, we explore the intersocietal guidelines on peripheral arterial disease in patients with diabetes and foot ulcers authored by the International Working Group on the Diabetic Foot (IWGDF), the European Society for Vascular Surgery (ESVS), and the Society for Vascular Surgery (SVS). Dr. Robert Fitridge is a Professor of Vascular Surgery at University of Adelaide in Australia. He is a member of the IWGDF and is also a member of the steering committee for the Global Vascular Guideline on the management of Chronic Limb-threatening Ischaemia. Dr. Vivienne Chuter is a Professor in the Department of Podiatry at Western Sydney University and Honorary Professor in the School of Health Science at The University of NewCastle. She is a member of the IWGDF. She has published extensively on diabetic foot disease and leads a clinically based research program focusing on the prevention and management of diabetes-related foot disease for Aboriginal and Torres Strait Islander people and for non-Indigenous Australians. Dr. Nicolaas Schaper is an emeritus professor of Endocrinology at Maastricht University Hospital in the Netherlands. Dr. Schaper was the coordinator of the European diabetic foot research consortium, Eurodiale. He is Chair of the 2023 Diabetic Foot Symposium (ISDF 2023) and is Chair of the IWGDF. Dr. Joseph L. Mills is a Professor of Vascular Surgery at Baylor in Houston, Texas. He is a member of the IWGDF. Dr. Mills is a leader in the vascular surgery global community, has served as president of the Peripheral Vascular Surgery Society, and is currently a member of the Surgery Residency Review Committee of the ACGME. Further reading and links: The intersocietal IWGDF, ESVS, SVS guidelines on peripheral artery disease in people with diabetes mellitus and a foot ulcer. Global vascular guidelines for CLTI Best-CLI Engaging patients and caregivers to establish priorities for the management of diabetic foot ulcers A systematic review of multidisciplinary teams to reduce major amputations for patients with diabetic foot ulcers A vein bypass first versus a best endovascular treatment first revascularisation strategy for patients with chronic limb threatening ischaemia who required an infra-popliteal, with or without an additional more proximal infra-inguinal revascularisation procedure to restore limb perfusion (BASIL-2): an open-label, randomised, multicentre, phase 3 trial Release of the National Scheme's Aboriginal and Torres Strait Islander Health and Cultural Safety Strategy 2020-2025; the impacts for podiatry in Australia: a commentary Editor's Choice - European Society for Vascular Surgery (ESVS) 2023 Clinical Practice Guidelines on Antithrombotic Therapy for Vascular Diseases Results of the CAPRIE trial: efficacy and safety of clopidogrel. Clopidogrel versus aspirin in patients at risk of ischaemic events Low-Dose Aspirin for the Primary Prevention of Cardiovascular Disease in Diabetic Individuals: A Meta-Analysis of Randomized Control Trials and Trial Sequential Analysis Diabetes, Lower-Extremity Amputation, and Death Outcomes in patients with chronic leg wounds in Denmark: A nationwide register‐based cohort study Pedal arch patency and not direct-angiosome revascularization predicts outcomes of endovascular interventions in diabetic patients with critical limb ischemia Effectiveness of bedside investigations to diagnose peripheral artery disease among people with diabetes mellitus: A systematic review. Performance of non-invasive bedside vascular testing in the prediction of wound healing or amputation among people with foot ulcers in diabetes: A systematic review. Effectiveness of revascularisation for the ulcerated foot in patients with diabetes and peripheral artery disease: A systematic review. The Society for Vascular Surgery Lower Extremity Threatened Limb Classification System: Risk stratification based on Wound, Ischemia, and foot Infection (WIfI). Surgery or Endovascular Therapy for Chronic Limb-Threatening Ischemia. A vein bypass first versus a best endovascular treatment first revascularisation strategy for patients with chronic limb threatening ischaemia who required an infra-popliteal, with or without an additional more proximal infra-inguinal revascularisation procedure to restore limb perfusion (BASIL-2): an open-label, randomised, multicentre, phase 3 trial. Mobile Applications: Society for Vascular Surgery Mobile App for Staging of Chronic Limb-Threatening Ischemia. European Society for Vascular Surgery Clinical Practice Guidelines Mobile Edition. Hosts: Dr. Naveed A. Rahman is a chief surgery resident at SUNY Upstate in Syracuse, NY. He will pursue a vascular surgery fellowship at the University of Maryland starting in 2024. His Doximity profile is https://www.doximity.com/pub/naveed-rahman-md. Twitter: @naveedrahmanmd Dr. Suzanne Stokmans is a fifth-year vascular surgery resident at the Isala Hospital in Zwolle, the Netherlands. Dr. Ezra Schwartz is a medical graduate from McGill University currently completing a Master of Medical Science in Medical Education at Harvard Medical School. He is an aspiring vascular surgeon and surgical education researcher. Twitter: @ezraschwartz10 Follow us @audiblebleeding Learn more about us at https://www.audiblebleeding.com/about-1/ and provide us with your feedback with our listener survey.
Commentary by Dr Hirotoshi Watanabe
Low Dose Aspirin has been a routine aspect of preeclampsia prevention since first mentioned by the ACOG's Hypertension in Pregnancy Task Force report, back in November 2013. Since that time, there has been several revisions of the criteria of who qualifies for low-dose aspirin in pregnancy. Nonetheless, there are calls and expert opinions challenging this “risk factor based” approach, favoring a more universal adoption. Additionally, the DOSE of low-dose aspirin has also come under recent critique. Is 81 mg the correct dose to use? Does aspirin have the potential to reduce preterm birth? In this episode, we will review a soon-to-be released clinical commentary from the AJOG (October 2023) which addresses these matters.
In this early pandemic study of COVID-19 confirmed hospitalized patients, researchers found two groups of individuals with biomarker profiles: the first had high fibrinogen levels in relation to C-Reactive proteins (CRP) and the second had an increase in D-Dimers in relation to CRP. These molecules generally increase in relation to CRP; however, here the researchers found that the fibrinogen and D-Dimers increased while the CRP stayed low. These cohorts were associated with higher likelihood of neurological long COVID. Let's review both the findings and the mechanisms. DrBeen: Medical Education Onlinehttps://www.drbeen.com/ FLCCC | Front Line COVID-19 Critical Care Alliancehttps://covid19criticalcare.com/ URL list (Sep. 7, 2023) Acute blood biomarker profiles predict cognitive deficits 6 and 12 months after COVID-19 hospitalization | Nature Medicinehttps://www.nature.com/articles/s41591-023-02525-y Clotting proteins linked to Long Covid's brain fog | Science | AAAShttps://www.science.org/content/article/clotting-proteins-linked-long-covid-s-brain-fog Physiology, Acute Phase Reactants - StatPearls - NCBI Bookshelfhttps://www.ncbi.nlm.nih.gov/books/NBK519570/#:~:text=Acute%20phase%20reactants%20(APR)%20are,acute%20and%20chronic%20inflammatory%20states. Fibrin Polymerization - an overview | ScienceDirect Topicshttps://www.sciencedirect.com/topics/immunology-and-microbiology/fibrin-polymerization#:~:text=Cross%2Dlinked%20fibrin%20is%20an,that%20stabilizes%20the%20platelet%20plug.&text=Thrombin%20also%20activates%20a%20thrombin,%E2%80%9CFibrinolysis%2C%E2%80%9D%20below). Determinants of the onset and prognosis of the post-COVID-19 condition: a 2-year prospective observational cohort study - The Lancet Regional Health – Europehttps://www.thelancet.com/journals/lanepe/article/PIIS2666-7762(23)00143-6/fulltext Role of C-Reactive Protein at Sites of Inflammation and Infection - PMChttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908901/#:~:text=Evidence%20suggests%20that%20CRP%20is,NO%20release%2C%20and%20cytokine%20production. Screening Tests in Haemostasis:Fibrinogen Assayshttps://practical-haemostasis.com/Screening%20Tests/fibrinogen.html D-Dimers • The Blood Projecthttps://www.thebloodproject.com/cases-archive/d-dimers/d-dimers/ Low-Dose Aspirin and the Risk of Stroke and Intracerebral Bleeding in Healthy Older People: Secondary Analysis of a Randomized Clinical Trial | Geriatrics | JAMA Network Open | JAMA Networkhttps://jamanetwork.com/journals/jamanetworkopen/fullarticle/2807630#:~:text=In%20this%20secondary%20analysis%20of,overall%20risk%20of%20intracranial%20bleeding. Disclaimer:This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only. Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional. dr beenfibrinogenflccclong covidlong story short
Dr. Centor discusses the risk for anemia in older patients receiving aspirin for primary prevention with Dr. Zoe McQuilten.
It's In the News, a look at the top stories and headlines from the diabetes community happening now. Top stories this week: Abbott acquires Bigfoot, a new study looks at low-dose aspirin to prevent type 2, researchers look into whether the AI ChatGPT can answer FAQs about diabetes, Beyond Type Run is back for the NYC Marathon, and more! Our previous episode with Bigfoot Biomedical: https://diabetes-connections.com/?s=bigfoot Join us for Moms' Night Out! (use promo code School30 to save) Please visit our Sponsors & Partners - they help make the show possible! Take Control with Afrezza Omnipod - Simplify Life Learn about Dexcom Learn about Edgepark Check out VIVI Cap to protect your insulin from extreme temperatures Learn more about AG1 from Athletic Greens Drive research that matters through the T1D Exchange The best way to keep up with Stacey and the show is by signing up for our weekly newsletter: Sign up for our newsletter here Here's where to find us: Facebook (Group) Facebook (Page) Instagram Twitter Check out Stacey's books! Learn more about everything at our home page www.diabetes-connections.com Reach out with questions or comments: info@diabetes-connections.com Hello and welcome to Diabetes Connections In the News! I'm Stacey Simms and these are the top diabetes stories and headlines happening now XX In the news is brought to you by Edgepark simplify your diabetes journey with Edgepark XX Our top story this week – Abbott scoops up Bigfoot Biomedical. The deal is expected to close later this year – no financial terms yet disclosed. Abbott and Bigfoot have worked together since 2017 on a connected insulin pen system. Bigfoot Unity exclusively works with Abbott's FreeStyle Libre® Long time listeners will recall that Bigfoot was founded in 2015 around serving people with type 1 diabetes with a closed loop pump system that Byran Mazlish had developed for his wife and son. Mazlish was very secretive at first about the algorithm – this was before people were sure the FDA wouldn't crack down on them – so a journalist nicknamed him Bigfoot. Along the way, the company pivoted to CGM connected SmartPens. I believe Bigfoot was my third interview, back in 2015 – I'll ink up all of the interviews I've done with them in the show notes. https://diabetes-connections.com/?s=bigfoot https://www.prnewswire.com/news-releases/abbott-to-acquire-bigfoot-biomedical-furthering-efforts-to-develop-personalized-connected-solutions-for-people-with-diabetes-301918254.html XX Low-dose aspirin reduces the risk for type 2 diabetes among older adults and slows the increase in fasting glucose levels over time, new research finds. The data come from a secondary analysis of ASPREE, a double-blind, placebo-controlled trial of healthy adults aged 65 years or older, showing that 100 mg of aspirin taken daily for about 5 years did not provide a cardiovascular benefit but did significantly raise the risk for bleeding. It's a big study, more than 16-thousand people. This new analysis shows that individuals taking aspirin had a 15% lower risk for developing type 2 diabetes and that the medication slowed the rate of increase in fasting plasma glucose, compared with placebo, during follow-up. However, lead author Sophia Zoungas, MBBS, PhD, head of the School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia, says, "Major prescribing guidelines now recommend older adults take daily aspirin only when there is a medical reason to do so, such as after a heart attack… Although these new findings are of interest, they do not change the clinical advice about aspirin use in older people at this time." https://www.medscape.com/viewarticle/996058 XX A class-action lawsuit filed against Medtronic (NYSE: MDT)+ alleges that the company's insulin delivery devices shared patient data with third parties. The lawsuit — filed by the plaintiff “A.H.” in U.S. District Court in Central California — levels allegations against Medtronic and its MiniMed and InPen devices. It addresses MiniMed's transmission and disclosure of personally identifiable information and protected health information to Google and other third parties. Per the lawsuit, the data was transmitted via tracking and authentication technology, including Google Analytics, Crashlytics, Firebase Authentication and related tools. A.H. says these technologies, installed on the website and/or mobile applications, include the InPen iOS and Android applications. “Information about a person's health is among the most confidential and sensitive information in society, and its mishandling can have serious consequences, including embarrassment, discrimination, and denial of insurance coverage,” the lawsuit reads. A Medtronic spokesperson issued the following statement via email: We have strong processes, technologies, and people in place to safeguard and protect our information and systems, the information of our business partners, and most importantly, the privacy and safety of the patients and healthcare providers that use our products.” https://www.massdevice.com/lawsuit-patient-data-sharing-medtronic-diabetes/ XX Interesting new way to look at type 2 – not weight loss or medication, but about reducing how much blood glucose goes up and stays up after eating and drinking. University of Virginia Daniel Cox says this is called Glucose Everyday Matters, or GEM – aims to prevent blood sugar spikes via educated food and drink selection. This is coupled with physical activity to hasten recovery when blood-sugar spikes do occur. So someone might indulge in a piece of fruit or a small, sweet treat, knowing how it will affect them, and then go for an evening stroll to help even out their blood sugar. Sounds really simple, but in its first study, it helps almost 70-percent of people put their type 2 into remission without weight loss or medication. The National Institutes of Health has provided $3.5 million for a large-scale clinical trial Cox himself went from an A1C of 10.3 at the time of diagnoses to reading consistently under 6.0 for the past 13 years on no medication using his approach. https://newsroom.uvahealth.com/2023/08/31/radical-new-approach-to-managing-type-2-diabetes-receives-3-5-million/ XX Final preparations are in place to initiate the first clinical site for DIAGNODE-3 in the United States, and additional sites are expected to be initiated over the coming months. Approximately 10-12 clinical sites across the US are planned to be initiated, expanding the DIAGNODE-3 trial in the US and eight European countries to approximately 60 clincal sites in total. DIAGNODE-3 is designed to confirm the efficacy and safety of the antigen-specific immunotherapy Diamyd® in patients aged 12 to 29 years recently diagnosed with type 1 diabetes and carrying the genetic HLA DR3-DQ2 marker. Approximately 40% of all screened patients carry the genetic HLA DR3-DQ2 haplotype. This proportion aligns well with expectations based on previous Diamyd® clinical trials and published epidemiological research. Supported by published retrospective analyses and prospective clinical trials, the presence of the genetic HLA DR3-DQ2 haplotype determines the likelihood of responding to Diamyd® therapy, and serves as one of the main inclusion criteria in the DIAGNODE-3 trial. "Patient recruitment is a complex and central element in any trial and it is encouraging to see a significant and continuous uptick in the screening rate and that the observed frequency of the genetically defined responder group enrolled into DIAGNODE-3 confirms our previous observations", says Ulf Hannelius, President & CEO of Diamyd Medical. "This shows the operational and clinical feasibility of our precision medicine approach to Type 1 Diabetes and we look forward to expanding the trial to the United States". https://finance.yahoo.com/news/registrational-phase-iii-trial-type-142600082.html XX A low-carbohydrate diet during pregnancy may have some benefits in gestational diabetes, but overall, low-carbohydrate diets are not associated with any significant differences in outcomes. That was the conclusion of a presentation at the ADA Scientific Sessions. That was back in June but I just learned about it, so I'm passing along to you in case you missed it as well. During a debate at the American Diabetes Association Scientific Sessions, Amy M. Valent, DO, MCR, associate professor in the division of maternal-fetal medicine in the department of obstetrics and gynecology at Oregon Health & Science University, said identifying Teri L. Hernandez, PhD, RN, associate dean of research and scholarship in the College of Nursing and professor in the department of medicine and the division of endocrinology, metabolism and diabetes at the University of Colorado Anschutz Medical Campus, agreed that the first line of therapy with gestational diabetes is nutrition. However, Hernandez said, low-carbohydrate diets are not the only approach in gestational diabetes treatment with nutrition. Currently, dietary advice for treating gestational diabetes is inconsistent, and current professional guidelines have limitations and biases, according to Valent. Different diet strategies include low-carbohydrate, low glycemic index and total energy restriction eating plans, according to Valent. Valent said ACOG guidelines recommended a low-carbohydrate diet for gestational diabetes until the most recently revised edition in January. Valent reviewed several major landmark studies demonstrating that gestational diabetes treatment can decrease pregnancy complications such as preeclampsia and large for gestational age infants. “These studies were in the era where treatment of diabetes in pregnancy involved recommending a low-carbohydrate diet,” Valent said. “The concern with lowering carbohydrates is the risk of consuming lower nutrient-dense foods and resulting in the body to produce ketones, which may be associated with negative effects on the developing baby.” “Pregnancy is dynamic. Nobody's the same today as they were yesterday. They're going to be different 1, 2 or 3 weeks from now, and the nutritional demands and the fetal growth and development stage are going to be different,” Valent said. “So, nutritional demands are going to vary.” Hernandez also added that women and girls tend to be priced out of good nutritional patterns, which is an issue not only in the pregnancy field, but also in the global community. According to Hernandez, it is important to create ways moving forward to identify what nutritional patterns are best that are also affordable for families, especially in lower-income settings. https://www.healio.com/news/womens-health-ob-gyn/20230905/experts-debate-benefits-of-lowcarb-diets-for-gestational-diabetes XX XX Commercial – Edgepark XX Can ChatGPT help answer questions about diabetes? In a recent study published in the journal PLoS ONE, researchers tested chatGPT, a language model geared for discussion, to investigate whether it could answer frequently asked diabetes questions. In the present study, researchers evaluated ChatGPT's expertise in diabetes, especially the capacity to answer commonly requested questions related to diabetes in a similar manner as humans. The 'Frequently Asked Questions' section of the Diabetes Association of Denmark's website, viewed on 10 January 2023, included eight questions. The researchers designed the remaining questions to correlate to particular lines on the 'Knowledge Center for Diabetes website and a report on physical activity and diabetes mellitus type 1. Across the 10 questions, the proportion of correct responses ranged from 38% to 74%. Participants correctly identified ChatGPT-generated replies 60% of the time, which was over the non-inferiority threshold. Males and females had 64% and 58% chances of accurately recognizing the artificial intelligence-generated response, respectively. Individuals who had past contact with diabetes patients had a 61% chance of precisely answering the questions, compared to 57% for those who had no prior contact with diabetes patients. In contrast to the initial premise, participants could discern between ChatGPT-generated and human-written replies better than tossing a fair coin. While ChatGPT demonstrated some potential for accurately answering frequently asked questions, issues around misinformation and the lack of nuanced, personalized advice were evident. As large language models increasingly intersect with healthcare, rigorous studies are essential to evaluate their safety, efficacy, and ethical considerations in patient care, emphasizing the need for robust regulatory frameworks and continuous oversight. https://www.news-medical.net/news/20230905/Can-ChatGPT-be-a-diabetes-consultant-Study-probes-the-potential-and-pitfalls.aspx XX SAN MATEO, Calif., Aug. 24, 2023 /PRNewswire/ -- On November 5, diabetes nonprofit Beyond Type 1 will join more than 550 official charity partners and philanthropists raising awareness and funds while participating in the world's largest marathon, the TCS New York City Marathon. This year, the organization is expanding its 50-person team, Beyond Type Run, to include people living with type 1 or type 2 diabetes, as well as caregivers to those living with diabetes. "Since 2017, we've featured more than 200 runners on our teams who've exemplified what it means to survive and thrive with diabetes," said Beyond Type 1 CEO Deborah Dugan. Beyond Type 1 announces the 2023 NYC Marathon team to raise awareness and funds for people living with diabetes As a part of the Beyond Type Run team, runners will be advocating to raise awareness and funds for Beyond Type 1's portfolio of educational resources, awareness campaigns and peer-to-peer support programs for people impacted by diabetes. This advocacy is elevated through the NYRR Official Charity Partner Program, which offers opportunities for nonprofit organizations to raise funds to support their missions and services. Dexcom and Tandem Diabetes Care are presenting sponsors of Beyond Type Run for a fourth consecutive year. The TCS New York City Marathon Official Charity Partner Program has raised more than $440 million for more than 1,000 nonprofit organizations since its establishment in 2006. https://www.prnewswire.com/news-releases/team-of-50-individuals-impacted-by-diabetes-prepare-for-the-2023-tcs-new-york-city-marathon-301909163.html XX MNO update On the podcast next week.. tandem diabetes celebrity panel from friends for life – Hollywood, the NFL and NASCAR. Last week's episode was Benny off to college That's In the News for this week.. if you like it, please share it! Thanks for joining me! See you back here soon. ----
Dr. Geoffrey A. Donnan discusses his paper, "Low-Dose Aspirin and the Risk of Stroke and Intracerebral Bleeding in Healthy Older People". Show references: https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2807630
This week the hosts discuss research that shows women are diagnosed years later than men for the same diseases, and they look at a study that suggests low-dose aspirin may cause brain bleeding. Plus, they share a delicious recipe for beer battered smelt.
In this podcast, James Cave (Editor-in-Chief) and David Phizackerley (Deputy Editor) talk about the August 2023 issue of DTB. They discuss measurement of fractional exhaled nitric oxide (FeNO) in the management of asthma (https://dtb.bmj.com/content/61/8/114). They review a study that assessed the use of H. pylori eradication in people taking low-dose aspirin (https://dtb.bmj.com/content/61/8/116). The main article explores the evidence for the use of finerenone for CKD associated with type 2 diabetes (https://dtb.bmj.com/content/61/8/120). Please subscribe to the DTB podcast to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the DTB Podcast iTunes podcast page (https://podcasts.apple.com/gb/podcast/dtb-podcast/id307773309). If you want to contact us please email dtb@bmj.com. Thank you for listening.
In this episode of The Performance Medicine Show, Dr. Rogers answers YOUR health and wellness questions! What did you think of this episode of the podcast? Let us know by leaving a review! Connect with Performance Medicine! Sign up for our weekly newsletter: https://performancemedicine.net/doctors-note-sign-up/ Facebook: @PMedicine Instagram: @PerformancemedicineTN YouTube: Performance Medicine
Dr. Ebell and Dr. Wilkes discuss the POEM titled ' Twice-daily low-dose aspirin is similar to enoxaparin for thromboprophylaxis after inpatient treatment for fracture (PREVENT CLOT) '
Pulmonary embolism, coffee, when DOACs don't work, lipoprotein (a), and the marginal benefits of current CV therapy are the topics John Mandrola, MD, discusses in this week's podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I. Pulmonary Embolism - Positive Data on Thrombectomy Catheter That Avoids Thrombolytics in Acute PE https://www.medscape.com/viewarticle/981322 - Acute Outcomes for the Full US Cohort of the FLASH Mechanical Thrombectomy Registry in Pulmonary Embolism https://eurointervention.pcronline.com/article/acute-outcomes-for-the-full-us-cohort-of-the-flash-mechanical-thrombectomy-registry-in-pulmonary-embolism - PEERLESS Study https://clinicaltrials.gov/ct2/show/NCT05111613 - Ultrasound-facilitated, Catheter-directed, Thrombolysis in Intermediate-high Risk Pulmonary Embolism (HI-PEITHO) https://clinicaltrials.gov/ct2/show/NCT04790370 - A Prospective, Single-Arm, Multicenter Trial of Catheter-Directed Mechanical Thrombectomy for Intermediate-Risk Acute Pulmonary Embolism: The FLARE Study https://doi.org/10.1016/j.jcin.2018.12.022 II. Coffee Again - Coffee Linked to Reduced Cardiovascular Disease and Mortality https://www.medscape.com/viewarticle/981518 Enough With the Coffee Research and Other Distractions https://www.medscape.com/viewarticle/883709 - The impact of coffee subtypes on incident cardiovascular disease, arrhythmias, and mortality: long-term outcomes from the UK Biobank https://doi.org/10.1093/eurjpc/zwac189 III. DOAC and Mechanical Valves - PROACT Xa Trial of Apixaban With On-X Heart Valve Stopped https://www.medscape.com/viewarticle/981644 - Artivion Follows Recommendation to Stop PROACT Xa Clinical Trial https://investors.artivion.com/news-releases/news-release-details/artivion-follows-recommendation-stop-proact-xa-clinical-trial - PROACT Xa - A Trial to Determine if Participants With an On-X Aortic Valve Can be Maintained Safely on Apixaban https://clinicaltrials.gov/ct2/show/NCT04142658 - Dabigatran versus Warfarin in Patients with Mechanical Heart Valves https://www.nejm.org/doi/full/10.1056/nejmoa1300615 IV. Lipoprotein(a) - Aspirin Primary Prevention Benefit in Those With Raised Lp(a)? https://www.medscape.com/viewarticle/981602 - Aspirin for Primary Prevention of Cardiovascular Events in Relation to Lipoprotein(a) Genotypes https://www.jacc.org/doi/full/10.1016/j.jacc.2022.07.027 - A Randomized Trial of Low-Dose Aspirin in the Primary Prevention of Cardiovascular Disease in Women https://www.nejm.org/doi/full/10.1056/nejmoa050613 - Effect of Aspirin on Disability-free Survival in the Healthy Elderly https://www.nejm.org/doi/full/10.1056/NEJMoa1800722 - Effect of Aspirin on Cardiovascular Events and Bleeding in the Healthy Elderly https://www.nejm.org/doi/full/10.1056/NEJMoa1805819 - Effect of Aspirin on All-Cause Mortality in the Healthy Elderly https://www.nejm.org/doi/full/10.1056/NEJMoa1803955 You may also like: Medscape editor-in-chief Eric Topol, MD, and master storyteller and clinician Abraham Verghese, MD, on Medicine and the Machine https://www.medscape.com/features/public/machine The Bob Harrington Show with Stanford University Chair of Medicine, Robert A. Harrington, MD. https://www.medscape.com/author/bob-harrington Questions or feedback, please contact: news@medscape.net
O retorno do bolus com Joanne e Marcela falando sobre AAS na profilaxia primária para doença cardiovascular (DCV)! Elas abordam 3 tópicos: - História de AAS na prevenção de DCV - Recomendação atual e os principais estudos que motivaram a mudança de recomendação (ASPREE, ARRIVE E ASCEND) - O que fazer com quem já usa? Tá imperdível! Referências: 1. Aimo A, De Caterina R. Aspirin for primary prevention of cardiovascular disease: Advice for a decisional strategy based on risk stratification. Anatol J Cardiol. 2020;23(2):70-78. 2. Berger JS. Aspirin for Primary Prevention—Time to Rethink Our Approach. JAMA Netw Open.2022;5(4):e2210144. 3. Bowman L, et al. Effects of Aspirin for Primary Prevention in Persons with Diabetes Mellitus. N Engl J Med 2018; 379:1529-1539 4. Chiang KF, Shah SJ, Stafford RS. A Practical Approach to Low-Dose Aspirin for Primary Prevention. JAMA. 2019;322(4):301-302 5. Gaziano JM, et al. Aspirin to Reduce Risk of Initial Vascular Events - ARRIVE. Lancet 2018; 392: 1036–46 6. McNeil JJ, et al. Effect of Aspirin on All-Cause Mortality in the Healthy Elderly. N Engl J Med 2018; 379:1519-1528 7. Précoma DB, Oliveira GMM, Simão AF, Dutra OP, Coelho OR, Izar MCO, Póvoa RMS, et al. Atualização da Diretriz de Prevenção Cardiovascular da Sociedade Brasileira de Cardiologia – 2019. Arq. Bras. Cardiol. 2019;113(4):787-891 8. Raber I, et al. The rise and fall of aspirin in the primary prevention of cardiovascular disease. Lancet 2019; 393: 2155–67 9. US Preventive Services Task Force. Aspirin Use to Prevent Cardiovascular Disease: US Preventive Services Task Force Recommendation Statement. JAMA.2022;327(16):1577–1584.
I've been getting a lot of questions about aspirin and pregnancy. These are not “Can I take aspirin for my headache?” but instead “My doctor prescribed a daily low-dose aspirin. Why?”
American Heart Association recommendations regarding aspirin use in those with and without known cardiovascular disease.
In this Ask The Egg Whisperer episode, Ryan sent in a question. Here's what she asked, “I'm going into my frozen embryo cycle next week. You've mentioned that you have your patients take low-dose aspirin. I did an ERA cycle last month. My nurse told me it was up to me if I wanted to take it. I'm a type of person that likes yes or no answers during this process. Should I take it even though it wasn't recommended? My baseline ultrasound is next week, and I'm curious when to start the aspirin and when to stop taking it." Tune in to hear my answer to Ryan's question, and to other listener questions. Do you have questions about IVF?Click here to join Dr. Aimee for The IVF Class. The next live class call is on Monday, January 24, 2022 at 4pm PST, where Dr. Aimee will explain IVF and there will be time to ask her your questions live on Zoom. Click to find The Egg Whisperer Show podcast on your favorite podcasting app. Watch videos of Dr. Aimee answer Ask the Egg Whisperer Questions on YouTube. Sign up for The Egg Whisperer newsletter to get updates Dr. Aimee Eyvazzadeh is one of America's most well known fertility doctors. Her success rate at baby-making is what gives future parents hope when all hope is lost. She pioneered the TUSHY Method and BALLS Method to decrease your time to pregnancy. Learn more about the TUSHY Method and find a wealth of fertility resources at www.draimee.org.
10/15/21 - Host Doug Stephan and Dr. Ken Kronhaus of Lake Cardiology (352-735-1400) begin with a truly in-depth discussion of recently released studies that warn against daily use of low dose Aspirin. Dr. Ken offers his recommendation, and as usual, one size does not fit all. Then, Doug asks Dr. Ken if it's possible to take too much fish oil and speculation that too much could lead to Atrial fibrillation (A-fib), an irregular and often very rapid heart rhythm (arrhythmia) that can lead to blood clots in the heart. Finally, the who, what, when and why of getting a COVID booster shot.
For years, people have been told to take 1 baby aspirin a day to prevent your first heart attack or stroke. Cardiologist Dr. Aryan Aiyer joins Rick to tell him why that is not the case anymore.
The cause of death for Gabby Petito has been determined, even as the search for her boyfriend remains ongoing with no known solid lead -- so we'll go In Depth. Aspirin and heart attacks. You've probably heard the advice that's practically gospel by now: low-dose aspirin dramatically reduces the risk of a cardiovascular event. Well today, a medical panel has turned that guidance on its head. And why is Moderna charging poorer countries more for doses of its COVID vaccine? Raiders coach Jon Gruden is out of a job, over sexist, homophobic, and racist comments in emails. But is he just the tip of an NFL toxic culture iceberg? If your dog is hurt and needs a blood transfusion ... there's a new set of rules governing how that's done in California. And meet the new Superman..........he's bisexual and politically active. Learn more about your ad choices. Visit podcastchoices.com/adchoices
The cause of death for Gabby Petito has been determined, even as the search for her boyfriend remains ongoing with no known solid lead -- so we'll go In Depth.Aspirin and heart attacks. You've probably heard the advice that's practically gospel by now: low-dose aspirin dramatically reduces the risk of a cardiovascular event. Well today, a medical panel has turned that guidance on its head. And why is Moderna charging poorer countries more for doses of its COVID vaccine?Raiders coach Jon Gruden is out of a job, over sexist, homophobic, and racist comments in emails. But is he just the tip of an NFL toxic culture iceberg?If your dog is hurt and needs a blood transfusion ... there's a new set of rules governing how that's done in California.And meet the new Superman..........he's bisexual and politically active. To learn more about listener data and our privacy practices visit: https://www.audacyinc.com/privacy-policy Learn more about your ad choices. Visit https://podcastchoices.com/adchoices
Editor's Summary by Mary McDermott, MD, Deputy Editor of JAMA, the Journal of the American Medical Association, for the September 28, 2021 issue.
This episode is also available as a blog post: https://mdforlives.blog/2021/03/01/benefits-of-low-dose-aspirin/ --- Send in a voice message: https://anchor.fm/mdforlives/message
3/19 Titan Lifestyle with Big Dru * Our social media: https://linktr.ee/TitanMedicalCenter * Live Q&A on #Titanmedical social media! - TOTW: Injectable Therapy IGF-1 For a Healthy Mind & Body - Low-dose aspirin can help w/reducing risk of Covid death/ICU admissions - New York’s “Excelsior Pass” Covid-19 passport for venues/businesses - Why using hand dryers isn’t a good idea & how they spread germs - New study: Exercise vs eating less to lose weight, what really works UPCOMING EVENTS: Mar/27:NPC Florida Miami Advice (Pro Body Tech Empire Gym) Mar/28:Key West Car Show (Forza Tuned Clearwater) Apr/10:NPC Mel Chancey Champion Muscle Classic-Tampa May/15:Tampa Bay Swim Week @WTR Fashion Show May/15:New York Pro (Tampa) Jun/19:Deke Warner Mid Florida Classic Jul/31:Tampa Bay Jeep Fest 3/15/21 Weekly Newsletter: Injectable Therapy IGF-1 For a Healthy Mind & Body (https://conta.cc/30Lqwmu) Text:titanmedical to:22828 to get on our emailing list Titan podcasts: https://titanmedicallifestylepodcast.fireside.fm titan #titanmedical #bigdru #johntsikouris #health #medicalcenter #peptide #aminos #vitamins Click here for our link to the New patient Paperwork to get started with Titan & our full list of social media! https://linktr.ee/TitanMedicalCenter And of course you can call/text anytime for more info: 727-389-3220 or http://titanmedicalcenter.com/ We service NATIONWIDE! Text:titanmedical to:22828 to get on our emailing list About Titan Medical Center: We offer Hormone Replacement Therapy, Medical Weight Loss, Injectable Vitamin & Amino Therapies, Relationship, Bedroom Enhancing Therapies, On-Site or Nationwide Blood Work Testing, Peptide Therapies, In-House IV Therapy, & Primary Care. We are based in Tampa, Florida but YES we service NATIONWIDE! We can help you enhance your life and performance while operating at optimal health levels. We have medical doctors and start with blood work testing to get you on the right track! Some of our therapies are available without blood work testing. Call Titan Medical Center to learn how you can have a healthier, stronger life. We offer telemedicine (via FaceTime or Skype) from the comfort of your own home where you will see a licensed medical provider. Our Titan therapies are doctor prescribed & shipped directly to your doorstep from a licensed US pharmacy!
In this episode of The Common Sense MD, Dr. Rogers talks about low dose aspirin and how it can help prevent heart disease and colon cancer. What did you think of this episode of the podcast? Let us know by leaving a review! Connect with Performance Medicine! Sign up for our weekly newsletter: https://performancemedicine.net/doctors-note-sign-up/ Facebook: @PMedicine YouTube: Performance Medicine Audio
In this episode of The Common Sense MD, Dr. Rogers talks about low dose aspirin and how it can help prevent heart disease and colon cancer. What did you think of this episode of the podcast? Let us know by leaving a review! Connect with Performance Medicine! Sign up for our weekly newsletter: https://performancemedicine.net/doctors-note-sign-up/ Facebook: @PMedicine Instagram: @PerformancemedicineTN YouTube: Performance Medicine Audio
Vidcast: https://youtu.be/lVuiANbnAXM Low dose aspirin increases the chances of a live birth by up to 15% for women who had up to 2 previous miscarriages. This the conclusion of a study from Emory and the NIH. A group of 1228 women 18-40 years were randomized to receive 81 mg of aspirin and folic acid or folic acid alone daily for up to 6 cycles while attempting conception and continuing the regimen through 36 weeks of a successful gestation. Those who adhered to the regimen a minimum of 4 days per week enjoyed 15 more live births per 100 women and suffered 6 fewer pregnancy losses per 100 women. Recurrent pregnancy losses are heartbreaking but preventable. https://www.acpjournals.org/doi/full/10.7326/M20-0469 https://www.nichd.nih.gov/about/org/diphr/officebranch/eb/effects-aspirin #pregnancy #miscarriage #aspirin
More details and links to the studies mentioned in this episode can be found at www.yourfertilitypharmacist.com
Dr. Ebell and Dr. Wilkes discuss the POEM titled ' Low-dose aspirin beneficial for the prevention of preterm birth in nulliparas with singleton pregnancy '
This week the hosts discuss research that shows women are diagnosed years later than men for the same diseases, and they look at a study that suggests low-dose aspirin may cause brain bleeding. Plus, they share a delicious recipe for beer battered smelt.
Another socially distanced DTB podcast features James Cave (Editor-in-Chief) and David Phizackerley (Deputy Editor), who provide an overview of the July issue of DTB. This includes an editorial that discusses some of the challenges in supplying low-dose aspirin to pregnant women for prevention of pre-eclampsia, a DTB Forum article by Margaret McCartney on some of the challenges to evidence-based medicine during the coronavirus pandemic and a DTB Select update on the safety of ibuprofen in people with COVID-19. The main article discusses managing antiepileptic drugs before and during pregnancy for women with epilepsy, and this month's case report is of amiodarone-induced diffuse alveolar haemorrhage. Read the full issue: https://dtb.bmj.com/content/58/7 Please subscribe to the DTB podcast to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the DTB Podcast iTunes podcast page (https://podcasts.apple.com/gb/podcast/dtb-podcast/id307773309). Thank you for listening. Go well and stay well.
318 - Ask Dr. Angela - Who Takes Low Dose Aspirin During Pregnancy & Why? - The Ask Dr. Angela Podcast. Dr. Angela Jones, Board Certified OB/GYN answers all your personal health questions with quick humorous answers. Ask your own question at www.AskDrAngela.com
The Staying Young Show 2.0 - Entertaining | Educational | Health & Wellness
Are you trying to prevent heart disease by taking low dose aspirin? This is Judy Gaman and this is your Stay Young Medical Minute. New research out of Beth Israel Deaconess Medical Center and Harvard Medical School suggests that taking low-dose aspirin, or “baby aspirin”, once a day can do more harm than good—if a doctor hasn't told you to take it. It's estimated that around 6.6 million people in the US are taking low-dose aspirin—even though they haven't been advised to do so. Numerous studies have found that the risk for internal bleeding outweighs the benefits of taking aspirin to prevent heart disease. Now, if you have been advised to take low-dose aspirin by your doctor, continue to take it. Talk to your doctor if you have questions about preventing heart disease. This Stay Young Medical Minute is brought to you by Executive Medicine of Texas, a leader in preventative and proactive medicine. Learn why patients from around the globe trust Executive Medicine of Texas to their health. Visit EMTexas.com that's EMTexas.com. https://www.medicalnewstoday.com/articles/325833.php Thank you for listening to the Staying Young Medical Minute! With all the mixed messages on health, you need information that you can use and that you can trust. Listen in as the experts discuss all topics health related. It's time to STAY YOUNG and stay healthy! Each week we tackle a topic and often with leading scientists, best-selling authors, and even your favorite celebrities! As a listener of our show, your input is important to us. Please take a moment to fill out this quick survey so we can serve you better - https://survey.libsyn.com/stayingyoung2 For more information on The Staying Young Show, please visit our website at www.StayYoungAmerica.com, and subscribe to the show in iTunes, Stitcher, or your favorite podcast app. You can also reach out to our host, Judy Gaman on www.judygaman.com for book purchasing, and speaking opportunities in your area!
Interview with Randall S. Stafford, MD, PhD, MHS, author of A Practical Approach to Low-Dose Aspirin for Primary Prevention
Progression of Barrett's Esophagus to Malignancy. Low-Dose Aspirin and Gastrointestinal Bleeding. Functional Nausea and Vomiting Disorders in Adults. Cost Effectiveness of Universal Screening for Hepatitis C Virus.
For years, daily low-dose aspirin was being prescribed as a magic bullet to prevent heart attacks, strokes and other cardiovascular disease. Older Canadians were advised to undertake this regimen whether they had heart problems or not. Now there is evidence that the risks outweigh the benefits. The American Heart Association released the new guidelines and Libby reached Dr. Marc Ruel at the Ottawa Heart Institute to discuss. And - call it a manual with everything you need to know to push back against ageism. Author Ashton Applewhite says she wanted to erase many of the myths about later life. Libby reached her in NYC.
Dr. Jack Stockwell www.forbiddendoctor.com tells Host Doug Stephan that it's time to stop the daily Low Dose Aspirin and recommends better alternatives. Also learn why it's good to take Cod Liver Oil. Plus, lots more great information about maintaining your Good Health.
Hypertension in pregnancy with subsequent preterm birth is one of the leading causes of poor or fatal maternal and fetal complications. In 2014 the United States Preventative Services Task Force recommended the use of Low Dose Aspirin (81mg) to women who have risk factors for hypertension and preeclampsia in pregnancy.Dr. Jodi Abbott, OB-GYN, explains how aspirin may reduce preeclampsia that can cause severe complications in pregnancy.
In this episode we talk about taking a low dose aspirin everyday and the potential side effects. We also talk about some natural alternatives. We also talk about studies linking eye health and your brain. Anyone with macular degeneration, glaucoma, or other eye problems are at a much higher risk of getting dementia or Alzheimer's. We talk about the link between your eyes and your brain. We also talk about some natural ways to help your eyes.
Matt, Chris, and Jen talk about a study of whether low-dose aspirin to prevent vascular events should be weight dependent, the gang revisits placebo effects and wonders if it is all just regression to the mean, and Jen focuses on the empathy of our dogs. Journal club article: Low dose aspirin study
Dr. Holm, Carrie Hagberg, and Joan Hogan discuss various medical topics
Commentary by Dr. Valentin Fuster
Dr. Maryam Derogar discusses her manuscript "Discontinuation of Low-Dose Aspirin Therapy After Peptic Ulcer Bleeding Increases Risk of Death and Acute Cardiovascular Events." To view the print version of this abstract go to http://bit.ly/WmJAyK.
Hursts The Heart Update