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Living with Intention: The Daily Habits That Build a Life You Love This week, Melissa continues the conversation from Episode 239 — The #1 Thing Standing Between You and the Life You Want — where she shared the importance of getting clear on what you want. Now, in Part Two, she goes deeper into what to do once you've found that clarity, and how to live with intention even in the middle of life's stress, chaos, and constant demands. Click here to listen to part one on Apple! Click here to listen and read on our website! In this episode, Melissa shares insights from a workshop she recently gave to women at her church about living intentionally and managing the mental load that comes with modern life. She explains what "intentional living" really means — making choices based on your values and goals instead of defaulting to busyness or comparison — and walks through a practical exercise you can do right now: asking yourself, What do I really want? She guides listeners through a journaling activity that reveals recurring themes, hidden desires, and areas where you might need more clarity. Then, she moves into the second half of the conversation — managing stress in real life. From a day spent painting with her kids that turned chaotic to simple strategies for lowering stress hormones like dopamine, serotonin, and oxytocin, Melissa shows that living intentionally doesn't mean living perfectly — it means noticing what's working and making small, conscious adjustments. She also highlights one of the most underused yet powerful tools for reducing anxiety and increasing self-awareness: journaling. Melissa shares research showing its benefits and how writing down what's in your head — no matter how messy — can be both healing and clarifying. This episode is a gentle, encouraging reminder that you don't have to overhaul your life to live more intentionally. Sometimes it's as simple as pausing, reflecting, and asking: What's one thing I can do today to move closer to the life I truly want? LINKS: All Links Family Brand! stan.store/familybrand familybrand.com/quiz familybrand.com/retreats. Episode Minute By Minute: 00:00 – Welcome to Part Two of the Living with Intention series 01:00 – Why this episode stands alone but connects to clarity (Part One) 02:00 – What intentional living actually means — and what it doesn't 03:30 – Knowing what you want and living in alignment with it 05:00 – Why this question — "What do I want?" — keeps showing up 06:30 – The writing exercise: ask yourself the question seven times 08:00 – Identifying patterns and themes in your answers 09:00 – How clarity leads to alignment and purpose 10:00 – Transition: managing the mental load of daily life 11:00 – The painting story — and how "small stress" still adds up 12:30 – The four happiness chemicals and how to activate them 13:30 – Dopamine: reward yourself and celebrate small wins 14:00 – Oxytocin: connection through touch, kindness, and service 14:30 – Serotonin: stability through sun, nature, and mindfulness 15:00 – Endorphins: joy through laughter, movement, and music 16:00 – The surprising science behind journaling and stress relief 17:30 – Why journaling is powerful — and why we often avoid it 19:00 – How confronting your thoughts can lead to healing 20:00 – Creating your personal plan of action 21:00 – One small step toward more peace and less stress 22:00 – Closing encouragement: be still, do what brings you joy, and live with intention
What happens when a former military cop, existentialist philosopher, and Substack firebrand walks into a podcast? You get this riveting conversation between Corey and Christopher Armitage, who pulls no punches when it comes to democracy, resistance, and why “soft secession” might be the only sane response to creeping authoritarianism. Chris is a U.S. Air Force veteran, former law enforcement officer, prolific writer, and founder of The Existentialist Republic. From his early days in New Jersey wrestling circles to his transformation into an outspoken advocate for “soft secession,” Chris shares deeply personal reflections and bold policy ideas aimed at confronting rising authoritarianism in America. Through a mix of dark humor, philosophical grounding, and actionable insights, Chris breaks down: What “soft secession” really means (hint: it's not Civil War 2.0), How localism and economic independence can fortify democracy, What ICE agents, serotonin, and Friedrich Nietzsche have in common, And why writing with relentless truth might be the ultimate form of resistance. This isn't just another political chat—it's a defibrillator for the democratic spirit. ⏱️ Timestamps & Key Topics [00:00] Welcome & Chris's multi-faceted background [00:04] Jersey roots, high school wrestling, and joining the Air Force [00:07] Serving as military police & navigating mental health in public service [00:13] From law enforcement to Substack: becoming a full-time writer [00:16] On Project 2025, ICE, authoritarianism, and systemic corruption [00:24] What is “soft secession” and why does it matter now? [00:29] Holding federal tax dollars in escrow — a controversial idea [00:33] Learning from Viktor Orbán, The Troubles, and global democracies [00:38] ICE overreach, due process violations, and local accountability [00:45] TP&R question: Can we still talk across our differences? [00:49] Dopamine vs. serotonin: the brain chemistry of politics [00:52] Final reflections: Hope, joy, and being a rebel for the good
Serotonin is often described as the “happiness molecule,” but its biology tells a larger story. Nearly every step in serotonin's synthesis and signaling, from the transport of dietary tryptophan to the enzymes that convert it, is influenced by nutrition.This episode examines how macronutrients, micronutrients, and gut-derived metabolites shape serotonin availability across the brain and body. Protein and carbohydrate balance determine how much tryptophan enters the brain. Specific vitamins and minerals serve as essential cofactors in its production and turnover, and so on…Understanding serotonin through this nutritional lens reframes it not as a simple neurotransmitter, but as a metabolic signal connecting diet, metabolism, and mood regulation.00:00 Introduction to Serotonin01:07 Evolutionary Role of Serotonin02:08 Nutritional Influence on Serotonin Synthesis02:55 Enzymatic Pathways of Serotonin Production04:21 Macronutrients: Impact on Serotonin06:32 Vitamins and Minerals: Impact on Serotonin09:27 Plant Compounds and Gut Microbiome: Impact on Serotonin10:24 Serotonin as a Biochemical Bridgehttps://pubmed.ncbi.nlm.nih.gov/40998119/
Episode Summary: In this episode of The Advancing Women Podcast, Dr. Kimberly DeSimone explores the science and social conditioning behind women's emotional sensitivity, and reframes it more accurately…as a strength, not a flaw. Research shows that women, on average, have lower baseline serotonin levels than men; but the story doesn't end there. This biological difference interacts with hormonal cycles and cultural expectations to shape how women feel, respond, and are perceived. Dr. DeSimone reveals how emotional responsiveness, so often dismissed as being “too emotional”, is actually a powerful form of emotional intelligence, leadership, and adaptive strength. From boardrooms to families, women's ability to read the room, sense tension, and lead with empathy is not “soft,” it's strategic. This episode offers both a scientific and empowering reframe that helps us honor our depth, protect our energy, and lead from emotional authenticity without apology. In this episode, you'll learn: Why women's serotonin levels affect emotional sensitivity — and what that means for mood and connection. How cultural conditioning distorts emotional intelligence into “overreaction.” The “gendered emotion hierarchy”, and how bias defines which emotions are labeled as strength or weakness. Why empathy and sensitivity are forms of data gatheringand leadership. How to protect your emotional energy through mindful boundaries and self-compassion. Key Takeaways: Sensitivity is strength. Emotional attunement is intelligence. Emotion is data, not drama. Boundaries protect your empathy. Reframing emotional intelligence is revolutionary leadership. Mentioned concepts: Serotonin and hormonal influence on mood Gender socialization and emotional labor Emotional intelligence and leadership Patriarchal bias in emotion valuation Mindful self-protection and boundary-setting #AdvancingWomenPodcast #EmotionalIntelligence #WomenInLeadership #SensitivityIsStrength #GenderBias #EmotionalIntelligenceAtWork #EmpathyInLeadership References: Don't Call Them Soft Skills: https://podcasts.apple.com/us/podcast/dont-call-them-soft-skills-with-communications/id1569849100?i=1000606194105 Brain and Behavior Research Foundation (2024). Male-Female Differences in the Serotonin System May Help Explain Differences in Stress Vulnerability, Study Suggests: https://bbrfoundation.org/content/male-female-differences-serotonin-system-may-help-explain-differences-stress-vulnerability National Institute of Health: Differences between males and females in rates of serotonin synthesis in human brain. https://pmc.ncbi.nlm.nih.gov/articles/PMC24674/ Let's Connect: Instagram: @AdvancingWomenPodcast https://www.instagram.com/advancingwomenpodcast/?hl=en Facebook: Advancing Women Podcast https://www.facebook.com/advancingwomenpodcast/ LinkedIn: Dr. Kimberly DeSimone https://www.linkedin.com/in/kimberly-desimone-phd-mba-ba00b88/
Send us a message with this link, we would love to hear from you. Standard message rates may apply.We share a joyful wedding recap and travel bits, then pivot to a clear guide on Seasonal Affective Disorder: what it is, who it affects, why it happens, and the tools that help. Practical and compassionate advice to steady mood, sleep, and energy through winter.• defining Seasonal Affective Disorder and its seasonal pattern• key symptoms including oversleeping and carb cravings• distinguishing normal winter dips from functional impairment• who is at higher risk and why geography matters• biology of light, circadian rhythm, melatonin and serotonin• evidence-based treatments including light therapy, CBT and medication• practical routines for light exposure, activity and social connection• when to seek help and how to prepare for a visitYou can email us at your checkuppod@gmail.comYou can look at our website to find all of our old episodesReferences1. Seasonal Affective Disorder: Common Questions and Answers. Galima SV, Vogel SR, Kowalski AW. American Family Physician. 2020;102(11):668-672.2. Seasonal affective disorder. National Library of Medicine (MedlinePlus).3. Seasonal Affective Disorder: An Overview. Magnusson A, Boivin D. Chronobiology International. 2003;20(2):189-207. doi:10.1081/cbi-120019310.4. Seasonal Affective Disorder: A Clinical Update. Westrin A, Lam RW. Annals of Clinical Psychiatry : Official Journal of the American Academy of Clinical Psychiatrists. 2007 Oct-Dec;19(4):239-46. doi:10.1080/10401230701653476.5. Seasonal Affective Disorders. Saeed SA, Bruce TJ. American Family Physician. 1998;57(6):1340-6, 1351-2.6. Seasonal Affective Disorder. Kurlansik SL, Ibay AD. American Family Physician. 2012;86(11):1037-41.7. Seasonal Sensitivity and Psychiatric Morbidity: Study About Seasonal Affective Disorder. Fonte A, Coutinho B. BMC Psychiatry. 2021;21(1):317. doi:10.1186/s12888-021-03313-z.8. Melanopsin, Photosensitive Ganglion Cells, and Seasonal Affective Disorder. Roecklein KA, Wong PM, Miller MA, et al. Neuroscience and Biobehavioral Reviews. 2013;37(3):229-39. doi:10.1016/j.neubiorev.2012.12.009.9. Role of Serotonin in Seasonal Affective Disorder. Gupta A, Sharma PK, Garg VK, Singh AK, Mondal SC. European Review for Medical and Pharmacological Sciences. 2013;17(1):49-55.Support the showSubscribe to Our Newsletter! Production and Content: Edward Delesky, MD & Nicole Aruffo, RNArtwork: Olivia Pawlowski
On this episode of Vitality Radio, Jared sits down with longtime friend and microbiome expert Max Willis, Chief of Research and Development at Solaray, to uncover the next generation of probiotic science. Together they explore how specific bacterial strains can influence mood, metabolism, cardiovascular function, and immune balance, and how new discoveries are reshaping what we know about the gut-brain connection. Max explains how advances in microbiome research are moving beyond digestion—showing how unique strains may support healthy stress response, memory, cholesterol, and healthy blood pressure. He also discusses postbiotics and why even “heat-killed” bacteria may still play a beneficial role in immune and gut support. Jared and Max discuss how the updated Solaray Microbiome line improves on the original formulas through better strain diversity, FODMAP-friendly prebiotics, postbiotic metabolites, and acid-resistant enteric capsules for improved delivery. The conversation dives into the connection between microbial diversity and overall vitality, offering listeners simple, science-based ways to support their gut ecosystem naturally.Products:New Solaray Mycrobiome FormulasVisit the podcast website here: VitalityRadio.comYou can follow @vitalitynutritionbountiful and @vitalityradio on Instagram, or Vitality Radio and Vitality Nutrition on Facebook. Join us also in the Vitality Radio Podcast Listener Community on Facebook. Shop the products that Jared mentions at vitalitynutrition.com. Let us know your thoughts about this episode using the hashtag #vitalityradio and please rate and review us on Apple Podcasts. Thank you!Just a reminder that this podcast is for educational purposes only. The FDA has not evaluated the podcast. The information is not intended to diagnose, treat, cure, or prevent any disease. The advice given is not intended to replace the advice of your medical professional.
This week on Raising Serotonin, I'm talking about why strength not “perfection” should be your focus. As I step into year six of the podcast, I reflect on my journey of growth, facing fear, and learning to embrace change.I share my story of moving from a place of misery to one of resilience, and why taking ownership of your life is so powerful. I also tackle the harmful trends around body image, like the “Pilates body,” and remind you that wellness isn't about fitting a mold, it's about becoming stronger mentally, emotionally, physically, and spiritually.In this episode, I cover:How fear of the unknown can hold you back, and how to move past itThe 1% rule: getting stronger every single dayChoosing one area of strength to focus on for long-term growthWhy chasing a “perfect” body is harmfulCaring for your body as your templeIf you've ever felt stuck, insecure, or pressured by body standards, this episode is for you. My message: stop comparing, start strengthening, and honor the body and life you've been given.Let's finish 2025 stronger than ever, not smaller, not perfect, but powerful in every way that matters.FOLLOW RAISING SEROTONIN ON INSTAGRAM HERE Support the show
Serotonin ist als „Glückshormon“ bekannt. Dabei ist der Botenstoff eigentlich kein Hormon und kann außerdem noch viel mehr, als auschließlich unser Glücksgefühl zu beeinflussen. Erst allmählich entdeckt die Wissenschaft, was Serotonin alles kann. Das weckt Hoffnungen, Krankheiten künftig gezielter therapieren zu können. Mehr über die Arbeit unseres Gesprächspartners Prof. Michael Bader am Max Delbrück Center erfahrt ihr hier. >> Artikel zum Nachlesen: https://detektor.fm/wissen/forschungsquartett-serotonin
Serotonin ist als „Glückshormon“ bekannt. Dabei ist der Botenstoff eigentlich kein Hormon und kann außerdem noch viel mehr, als auschließlich unser Glücksgefühl zu beeinflussen. Erst allmählich entdeckt die Wissenschaft, was Serotonin alles kann. Das weckt Hoffnungen, Krankheiten künftig gezielter therapieren zu können. Mehr über die Arbeit unseres Gesprächspartners Prof. Michael Bader am Max Delbrück Center erfahrt ihr hier. >> Artikel zum Nachlesen: https://detektor.fm/wissen/forschungsquartett-serotonin
Serotonin ist als „Glückshormon“ bekannt. Dabei ist der Botenstoff eigentlich kein Hormon und kann außerdem noch viel mehr, als auschließlich unser Glücksgefühl zu beeinflussen. Erst allmählich entdeckt die Wissenschaft, was Serotonin alles kann. Das weckt Hoffnungen, Krankheiten künftig gezielter therapieren zu können. Mehr über die Arbeit unseres Gesprächspartners Prof. Michael Bader am Max Delbrück Center erfahrt ihr hier. >> Artikel zum Nachlesen: https://detektor.fm/wissen/forschungsquartett-serotonin
Inspired by The Creative Act, we explore how to balance both — so you can stay inspired, grounded, and fully present in your art.Creativity is chemistry:Dopamine gives you spark + Serotonin gives you peace.
Leyla Muedin, a registered dietitian nutritionist, discusses the gastrointestinal (GI) side effects commonly experienced by patients using GLP-1 medications such as Ozempic and Rybelsus. Leyla introduces a nutraceutical called Digexin, created by N-X-T-U-S-A, which has shown promise in mitigating these side effects and improving overall well-being. The episode highlights the need for patients to prioritize animal protein intake and incorporate strength training to maintain muscle mass, especially when taking GLP-1 medications. Leyla emphasizes the importance of developing healthy habits and lifestyle changes to sustain weight loss after discontinuing these drugs.
In this Huberman Lab Essentials episode, I explore the science of gratitude and how to develop an effective, research-supported gratitude practice. I explain why common gratitude practices (like simply listing things you're grateful for) are far less impactful than engaging in story-based gratitude practices. I also explain how being grateful activates specific brain regions, which enhance calm, social connection and motivation, while reducing anxiety and inflammation. Finally, I share why we can't simply trick our brains into feeling grateful and describe a practical weekly gratitude practice that will improve both your mental and physical well-being. Read the episode show notes at hubermanlab.com. Thank you to our sponsors AGZ by AG1: https://drinkagz.com/huberman Eight Sleep: https://eightsleep.com/huberman Our Place: https://fromourplace.com/huberman Timestamps (0:00) Gratitude (0:30) Gratitude Practice Benefits (3:22) Pro-Social vs Defensive Behaviors, Gratitude (6:25) Sponsor: Eight Sleep (8:07) Serotonin, Brain & Context, Gratitude Mindset (14:02) Context, Can You Lie to Yourself? (14:48) Effective Gratitude Practice, Tools: Receiving Gratitude, Story (21:18) Sponsor: AGZ by AG1 (22:47) Tool: Find & Revisit Inspirational Stories (27:30) Heartfelt Intention, Genuine Thanks (29:42) Sponsor: Our Place (31:03) Gratitude Practice Benefits for Anxiety, Fear & Motivation (33:29) Gratitude Practice Benefits for Immune System (36:02) Recap: Establishing an Effective Gratitude Practice Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices
With a calcium score of zero, is there any fat in your diet? Are there any recommended supplements for IBS?What is the safest and most appropriate dose of vitamin D3 for most seniors?
INFINITY Study on the timing of thyroid medication ingestionI have a growth near my eye that is changing in color and becoming crusty. What should I do?I've been suffering from hip pain for the last three years. Any suggestions on what to do?Could toxic exposures like mold cause conditions like low thyroid or autoimmunity?
You've been told your phone is just a tool. But what if it's quietly rewiring your motivation, eroding your focus, and crowding out the single chemical your brain craves most - connection?This week on Live Well Be Well, neuroscientist and author TJ Power joins me to explore the science of dopamine, focus, and digital balance. TJ, who developed the DOSE model - dopamine, oxytocin, serotonin, endorphins - reveals how our screen habits are reshaping the brain's chemistry and stealing the satisfaction we once got from real connection.Drawing on his research in neuroscience and mental wellbeing, TJ explains how constant notifications, multitasking, and morning scrolling deplete dopamine, dull our motivation, and even affect emotional regulation. We discuss how to retrain your attention, protect your mornings, and strengthen the part of your brain responsible for self-control and flow.Here's what we dive into:The real data on phone addiction: how an average of 5.5 hours a day and 175 pickups rewires your dopamine system, and why under 3 hours supports better focus and happiness.Dopamine vs. Oxytocin - the neuroscience behind loneliness in the digital age, and how conversation and physical presence can restore deep fulfilment.Serotonin and sleep - how screen time late at night blocks natural serotonin cycles, sunlight absorption, and mood regulation.What is “brain rot”? TJ explains the neuroscience of effortless dopamine, gray matter changes, and why too much stimulation can damage attention networks.ADHD, attention, and environment - how our hunter-gatherer brains are struggling in a high-dopamine world, and what to do about it.AMCC (anterior mid-cingulate cortex) - your brain's “willpower muscle.” Learn how small acts of resistance build real discipline and creativity.Morning habits for dopamine balance - why checking your phone first thing drains focus, and how “computer before phone” rewires productivity.Practical digital boundaries - from the app TJ uses to track pickups (aiming for 50 a day) to phone-free meals that boost oxytocin and presence.Love,Sarah Ann
Send us a text- On-Demand Programme Link - https://mailchi.mp/bb2a7b851246/kairos-centre"It was aged....and I came across my [parents] stash of porn. I kept going back to view when they were out and took a few to my my room. They never knew".That is the very typical answer that I have been given by a large percentage of my adult clients when taking them through my History Taking Questionnaire. I ask them 188 questions over three 50 minutes sessions and their answers help me and them to build a profile understanding of the client from birth to current adult age; in order to answer the key question - for working with in EMDR and/or my Recovery Programme - 'What happened to you back there during childhood development'. It is not about allocating blame to parents. I say to clients that before allocating blame to parents, they would need to first consider the parents who parented their parents to see the batons and scripts handed to their parents; by implication - for the client to 'get it/understand' what the client is likely to be passing on to their children - despite their parents filtering off the worse excesses of what happened to then, so as not to pass the same excess to their children. Get it?It is about 'curiosity', not blame inquisition. It is about getting into the sandpit with the client.Answering the question 'What happened back there' - helps to better understand the brain's choice of preferred self-soothing behaviour for the adversity which was impacting them back there in childhood. (The client does not choose the type of compulsive behaviour. The brain chooses). That repeat (order from the menu!) over time, unwittingly became a compulsive response to a real or expected or perceived 'look alike' similar adversity.They have embarked on the hamster wheel; created a 'go-to'; carved out a habit; etched on the brain a neural pathway, to manage emotions by escape and camouflaging the adversity for a while. Problem: They are skipping the developmental brains training to use more positive life-skill coping strategies which other children are learning. Problem: They have to begin anew in adulthood to now learn for the first time, those postponed learning that were tools in the toolkit armoury which other children acquired.Problem: They are unaware that what is also happening at that early age, is that the physiology of the body was being changed to become 'use dependent' on the very potent neurochemical mix being secreted into their immature brain - called Dopamine, Serotonin, Oxytocin, norephrinepine - which are as potent as illegal street drugs.Get some help from The Kairos Centre. See what you cannot see. Begin to change that which you begin to better understand.Help someone: https://igg.me/at/ThekairosCentreHelp is here for you: bit.ly/pornaddictionhelpGary McFarlane (BA, LLM, Dip, Certs), Accredited EMDR Practitioner.Keywords:sex addiction, addicted, sex counseling, partner, porn addiction, recovery, sex drive, sex addiction recovery, therapist, therapy, talk show, sex therapy, podcast, sobriety, counseling, relationships, relationship counseling, relationship advice, addiction, couples, relationship therapy, couples therapy, sex therapist, online counseling, emdr therapy, emdr, sex therapy, addiction, conflict management, love addiction, love addiction therapy, behavior, marriage, marriage advice, psychology, codependency, sex life, neuroscience, sex ed, sober, sobriety, sexual dysfunction, relationship issues, sex coach, sexual, sexual trSupport the show
Most people try to “heal” their brain with supplements, mindset, or meditation—but this episode reveals the deeper protocol to actually grow a new brain, reverse stress damage, activate 1,100 healing genes, and unlock higher human performance at any age. You'll learn how neuroplasticity, mitochondria repair, plant-based NRF2 activators, and energetic practices work together to rebuild the brain and extend longevity. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Alberto Villoldo, Ph.D.—medical anthropologist, neuroscientist, energy medicine pioneer, and founder of The Four Winds Society, the gold-standard school for modern shamans. He has spent 25+ years studying Amazonian and Andean healing traditions, led the Biological Self-Regulation Lab at San Francisco State University to explore psychosomatic medicine, and authored more than 25 bestselling books on neuroscience, functional medicine, and energy healing. Few people on earth bridge ancient biohacking and modern brain science at this level. He also reveals the forms of nicotine that are safest (spoiler: it's not vapes or cigarettes), how nicotine works at the receptor level, and what the science says about long-term health effects. This episode blends functional medicine, brain optimization, and biohacking into one powerful, myth-busting breakdown. You'll learn: • How to grow a new brain every 22 days using neuroplasticity and mitochondria support • Why plant medicines and NRF2 activators can turn on 1,100 healing genes in 24 hours • The surprising link between nootropics, psychedelics, serotonin, and endogenous DMT • How mindset, belief systems, and placebo/nocebo shape immune function and metabolism • Why RFK's chronic disease warning connects to viral evolution and immune collapse • The real reason carnivore diets work—and when they fail without gut repair • Peptides, GLP-1 agonists, and the future of functional medicine hacking • Why most people sabotage themselves and how to stop fighting your own biology This is essential listening for anyone serious about biohacking, human performance, and longevity, and for those who want to understand how functional biology and mitochondrial science are redefining recovery, energy, and aging. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: NRF2 activation, Neurogenesis and hippocampus repair, Plant-based epigenetic triggers, Psychosomatic health, Serotonin to DMT conversion, Pineal gland methylation, Parasites and brain inflammation, Viral-driven evolution, GLP-1 agonists and longevity, Psilocybin lifespan extension, Autophagy and brain cleanup, Energetic medicine training, Functional peptides, BPC-157, Breathwork and CO2 tolerance, mTOR cycling, Cold exposure and dopamine, Mindset-driven immune function Thank you to our sponsors! • EMR-Tek | https://www.emr-tek.com/DAVE and use code DAVE for 40% off. • Essentia | Go to https://myessentia.com/dave and use code DAVE for $100 off The Dave Asprey Upgrade. • Timeline | Head to https://www.timeline.com/dave to get 10% off your first order. • fatty15 | Go to https://fatty15.com/dave and save an extra $15 when you subscribe with code DAVE. Resources: • Learn more from Alberto at: www.thefourwinds.com and www.albertovilloldo.net • Buy the book ‘Grow A New Brain': https://a.co/d/5lVhrVy • Business of Biohacking | Register to attend October 20-23 in Austin, TX https://businessofbiohacking.com/ • Danger Coffee: https://dangercoffee.com/discount/dave15 • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 — Trailer 1:25 — Introduction & Ayahuasca Story 3:15 — Shamanism Beyond Plant Medicine 6:53 — Losing Your Mind to Evolve 10:45 — The 22-Day New Brain Cycle 12:53 — Plant Communication & Direct Knowing 15:35 — Parasites, Liver Failure & Brain Damage 20:25 — Remote Healing & CIA Research 22:40 — Tryptophan, Turkey Farmers & Brain Chemistry 25:19 — Viruses as Evolutionary Drivers 30:30 — Psilocybin & Life Extension 35:25 — Healing with Mindset + Biology 38:52 — Spirit, Purpose & Growing Gods 43:49 — Plants, Protein & mTOR 49:07 — Training the Four Brains 51:16 — Cold Exposure: Pain vs Suffering 54:40 — Who Am I? Living the Question 55:25 — Closing See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
In this episode, I'm celebrating six incredible years of Raising Serotonin! I take a look back at where it all started, during one of the most challenging times in my life, and how this podcast has evolved alongside my own personal growth. I open up about what I've learned through the ups and downs, the lessons that shaped me, and the role this community has played in helping me grow into the person I am today.Over the past six years, Raising Serotonin has become more than just a podcast to me. It's been a space for healing, connection, and honest conversations about mental health, self-love, and becoming your best self through small, consistent shifts.As I look ahead, I'm so grateful for every single one of you who's been part of this journey. Here's to continuing to grow, learn, and raise serotonin together. FOLLOW RAISING SEROTONIN ON INSTAGRAM HERE Support the show
See all the Healthcasts at https://www.biobalancehealth.com/healthcast-blog The summer of 2025, the US has experienced record heat. Most Americans have been under a severe heat warning for months, which has caused me to review the symptoms, prevention and treatment for Heat Stroke. This summer's heat was unusual, however it may recur in the future, so we must learn to deal with the effect of prolonged exposure to dangerous heat. Heat stroke is not classically a stroke as you know it, however heat stroke is a condition of a different kind, but no less deadly. The conditions that can lead to heat stroke are listed below. Please think of these signs of Heat Stroke before you go outside in severe heat. At Risk Conditions for heat Stroke: High ambient temperature High body temperature (body temp of 104 or more) High humidity, Prolonged sun exposure (more than an hour at a time) Dehydration Loss of electrolytes through sweating which can result in heart attacks, seizures delirium and can lead to death. The hot weather we have been experiencing has been prolonged and has all the qualities described above that may lead to heat stroke: Temperatures above 90 degrees Fahrenheit, High Humidity (over 50%), Bright sunshine, causing body temp to rise rapidly and continue for a long time even after a person has gone inside to cool off in air conditioning. You Should be aware of the beginning signs of heat stroke so you can remove yourself from the heat before it becomes an emergency, and you can protect your family from heat stroke. The early signs/symptoms of heat stroke include: Heavy sweating/ or no sweating at all Thirst Weakness of muscles Headache And Dizziness When you develop these symptoms, please listen to the signs your body is sending you and seek a cool place inside away from heat and sunlight. If the symptoms don't resolve quickly, then take the steps below to prevent progression of symptoms to result in heat stroke. Lie down (heat stroke can cause you lose consciousness and hurt yourself if you pass out) Drink cool but not cold water continually Drink Electrolytes (preferably products that contain Potassium, and sodium, chloride, magnesium) with every other 12oz of water. If you don't have electrolytes, Gatorade can be substituted for electrolytes (It is only Potassium). If you are unprepared and away from civilization, put several shakes of salt into a glass of cool water and drink it. Apply icepacks on the areas of the body that can cool you quickly: Underarms, groin, and neck. This will cool your body down faster than just sitting in a cool space. Don't be alone. Ask someone to sit with you in case you pass out or seize, and they can call 911 to take you to the ER. They can also make sure you continue to drink water and take electrolytes. If you feel your headache or weakness getting worse call 911 yourself. That is a late sign of Heat Stroke. Lastly, Heat stroke can make a person act out, with a temporary personality change. The affected person can hit and push the people trying to help him or her. That means they are in the late stage of heat stroke, and they need IV fluids a cooling blanket and Medical help. Remember, heat stroke can be deadly, and immediate action must be taken. If you or someone else has the following symptoms, then Call 911: passes out or seizes, gets confused and wanders around, acts out and hits or pushes has a rapid heart rate, has a bounding pulse, has either hot dry or very damp skin, complains of a headache or dizziness, nausea, vomiting rapid shallow breathing, like panting Often, they will complain of feeling cold and they shiver even though the temperature is very hot. Don't Wait! call 911! In these cases, tell the 911 operator that you suspect heat stroke. So how do you prevent heat stroke? There are many ways to prevent heat stroke, if you recognize the conditions outside will put you at risk. First determine whether you are at high risk (below are the risks). Anyone can get heat stroke but people with the following conditions will develop heat stroke faster and more severely than healthy young individuals. The following conditions should best be treated by staying in a cool area inside away from the sun. Know the Symptoms of heat stroke and follow the directions listed above. Prepare yourself for heatstroke by carrying electrolytes more water than you think you will need, plastic zip locks to put ice in if needed High Risk Medical Conditions and Medications Previous History of a Heat Stroke The biggest risk for heat stroke is having had it in the past. People who have a history of heat stroke should be extra careful to avoid going outside or exercising in the heat and humidity. They should stay inside during the heat of the day or on days that put them at risk. If you have almost had a mild form that you acted promptly and were able to avert the severe symptoms, that still makes you at risk for heat stroke. Heart Disease or other Circulatory medical conditions Diseases of the circulatory system place you at risk for getting a more severe form of heat stroke more quickly, so limit your time in the heat. Sympathetic and Parasympathetic Imbalance, from genetics or medications Disease of the sympathetic and parasympathetic nervous systems that cause excessive fluid loss due to sweating or increased body heat can cause you to develop heat stroke with less time in the heat and sun. These conditions affect your ability to sweat, which is the way humans cool themselves down. Patients with these diseases don't sweat to cool yourself down like other people. Stay inside until the temperature and humidity is safer. Age above 50 We all know that we are not as physically able as we age, even if we use testosterone pellets, so older age is a risk factor. Please limit your time outside in dangerous conditions to one hour at a time with 10 minutes or more inside a cool place before going back outside. Medications that put you at risk for heat stroke when exposed to heat and humidity You may be unaware of the risk that some medications have when it comes to heat stroke. Medications are part of our lives and most of the time we don't think about them causing problems or side effects, but many types of relatively safe medications can cause you to have heat stroke when the other folks around you are completely normal. My Experience with Heat Stroke I was playing golf in August in St. Louis, when the starting temperature at 8:30 am was 88 degrees F, and the humidity was 65%. Being me, I thought to myself,” Well I'm in good shape because I have minimal body fat and good muscles, I should be able to golf with 3 other women even in this heat.” That day the humidity increased to 80% and the temp was over 90. Then the Pro announced that we had to stay on the cart path. Well that makes golf a lot harder…,it takes twice as many steps during a round and it requires even more exertion than walking the course and dragging a bag behind you….but I'm not a quitter (but clearly I was not thinking about being sick and taking my life in my hands)…which means I was stupid! I want all of you to be smarter than I was! Right away I started sweating profusely so much so that I had to change my golf glove three times in 6 holes. I still felt ok, but I couldn't hit the ball as far as usual, and I continued to sweat. Despite 7 bottles of water, 2 with electrolytes, I started getting a headache, and then I couldn't make contact with the golf ball. My balance was off….” Uh-oh,” I thought, “it's happening”….At that point I knew I had to go inside but was far away from the club house. I continued one more hole and I was dizzy and had poor balance….so I quit, and I drove the cart back to the club house not finishing the 9 holes. I sat inside, drank water took another packet of electrolytes and put ice packs under my arms and laid down in the women's locker room until my headache was bearable, but I knew I was not going to be productive the rest of the day. It took 24 hours of lying down in a cool room, drinking quarts of water and taking electrolytes, putting ice around my neck and head, and doing nothing else! I kept thinking “why did the heat and humidity affect me and not the other 3 women?” We are all in good shape for our ages 60-70, and we all exercise and lift weights as well as play golf a few times a week, so I thought about what my risk factors were. Finally, I checked out all the medications and supplements I am on and found that some of them put me at risk! This incident made me look up the all the meds that can impact people and increase their risk of getting heat stroke. Medications That Increase Risk of Heat Stroke Diuretics- Spironolactone is a diuretic given to all women who take T pellets to prevent facial hair and acne. It can cause dehydration in hot weather unless enough water, and electrolytes are taken to replenish body fluids. Other reasons for taking a diuretic is hypertension, heart disease, swelling, and poor circulation. eg Hydrochlorothiazide (HCTZ) and Maxide are diuretics. Beta Blockers- such as Metoprolol, Propranolol slow down the heartbeat and reduce blood pressure. The actions of Beta blockers slow the cooling mechanism of the body. Antidepressants- There ae many types of antidepressants but the “Serotonin-reuptake-inhibitors” such as Lexapro, and Wellbutrin can increase the risk of Heat Stroke, but the mechanism is not known. Amphetamines like ADD medicine, Sleep Apnea drugs, and old-fashioned weight loss pills speed up the heart rate, increase baseline body temperature and decrease the body's ability to cool itself. Thyroid Replacement-Thyroid replacement increases the heat produced by muscle tissue therefore it increases body temperature. This causes a patient on thyroid to have fewer degrees to get to a critical body temperature. I will leave you with the warning that hot weather can kill you and knowing the signs and symptoms of Heat Stroke is the first step toward helping yourself and others avoid the worst consequences. If you have medical conditions or take medications that increase your risk of developing heat stroke you should spend most of your time indoors staying cool when heat and humidity is highest. I will leave you with the warning that hot weather can kill you and knowing the signs and symptoms of Heat Stroke is the first step toward helping yourself and others avoid the worst consequences. If you have medical conditions or take medications that increase your risk of developing heat stroke you should spend most of your time indoors staying cool.
For most people, the advice is simple: stop eating after dinner to improve digestion, support deeper sleep, and boost long-term health. But as with all things in life, there are exceptions and in some cases, a small nighttime snack can actually be beneficial. On today's show we'll break down both sides of the debate and cut through the confusion to decide whether eating before bed supports or sabotages your goals. Join me on Cabral Concept 3533 as we explore whether you should (or shouldn't) eat before bed and how to personalize the answer for your own health journey. Enjoy the show, and let me know what works best for you! - - - For Everything Mentioned In Today's Show: StephenCabral.com/3533 - - - Get a FREE Copy of Dr. Cabral's Book: The Rain Barrel Effect - - - Join the Community & Get Your Questions Answered: CabralSupportGroup.com - - - Dr. Cabral's Most Popular At-Home Lab Tests: > Complete Minerals & Metals Test (Test for mineral imbalances & heavy metal toxicity) - - - > Complete Candida, Metabolic & Vitamins Test (Test for 75 biomarkers including yeast & bacterial gut overgrowth, as well as vitamin levels) - - - > Complete Stress, Mood & Metabolism Test (Discover your complete thyroid, adrenal, hormone, vitamin D & insulin levels) - - - > Complete Food Sensitivity Test (Find out your hidden food sensitivities) - - - > Complete Omega-3 & Inflammation Test (Discover your levels of inflammation related to your omega-6 to omega-3 levels) - - - Get Your Question Answered On An Upcoming HouseCall: StephenCabral.com/askcabral - - - Would You Take 30 Seconds To Rate & Review The Cabral Concept? The best way to help me spread our mission of true natural health is to pass on the good word, and I read and appreciate every review!
Join my FREE 3-Day Water Fast Challenge - October 15th. It's the exact protocol I use with pro athletes and Fortune 500 CEOs to flush inflammation and kickstart autophagy. Sign up here! http://bit.ly/4nTILPt Here's what nobody tells you about happiness: it's not philosophical, it's biochemical, and there's a formula for it. Neuroscientist TJ Power joins me to decode the DOSE effect (Dopamine, Oxytocin, Serotonin, and Endorphins), the four neurochemicals that determine whether you wake up energized or apathetic, connected or isolated, fulfilled or constantly chasing more. The game-changer here is understanding that you can't scroll your way to serotonin or double-tap your way to oxytocin! Join the Ultimate Human VIP community for Gary Brecka's proven wellness protocols!: https://bit.ly/4ai0Xwg Get TJ Power's book, “The DOSE Effect“ here: https://bit.ly/4ofGiP8 Connect with TJ Power Website: https://bit.ly/4n5KxvX YouTube: https://bit.ly/4ohqBXW Instagram:https://bit.ly/3W6MZaq TikTok: https://bit.ly/3KGbk4y Facebook: https://bit.ly/42Eiblb X.com: https://bit.ly/4nKKSoN LinkedIn: https://bit.ly/476JlSU Thank you to our partners H2TABS: “ULTIMATE10” FOR 10% OFF: https://bit.ly/4hMNdgg BODYHEALTH: “ULTIMATE20” FOR 20% OFF: http://bit.ly/4e5IjsV BAJA GOLD: "ULTIMATE10" FOR 10% OFF: https://bit.ly/3WSBqUa EIGHT SLEEP: SAVE $350 ON THE POD 4 ULTRA WITH CODE “GARY”: https://bit.ly/3WkLd6E COLD LIFE: THE ULTIMATE HUMAN PLUNGE: https://bit.ly/4eULUKp WHOOP: JOIN AND GET 1 FREE MONTH!: https://bit.ly/3VQ0nzW MASA CHIPS: 20% OFF FIRST ORDER: https://bit.ly/40LVY4y VANDY: “ULTIMATE20” FOR 20% OFF: https://bit.ly/49Qr7WE AION: “ULTIMATE10” FOR 10% OFF: https://bit.ly/4h6KHAD A-GAME: “ULTIMATE15” FOR 15% OFF: http://bit.ly/4kek1ij PEPTUAL: “TUH10” FOR 10% OFF: https://bit.ly/4mKxgcn CARAWAY: “ULTIMATE” FOR 10% OFF: https://bit.ly/3Q1VmkC HEALF: 10% OFF YOUR ORDER: https://bit.ly/41HJg6S BIOPTIMIZERS: “ULTIMATE” FOR 15% OFF: https://bit.ly/4inFfd7 RHO NUTRITION: “ULTIMATE15” FOR 15% OFF: https://bit.ly/44fFza0 GOPUFF: GET YOUR FAVORITE SNACK!: https://bit.ly/4obIFDC GENETIC TEST: https://bit.ly/3Yg1Uk9 Watch the “Ultimate Human Podcast” every Tuesday & Thursday at 9AM EST: YouTube: https://bit.ly/3RPQYX8 Podcasts: https://bit.ly/3RQftU0 Connect with Gary Brecka Instagram: https://bit.ly/3RPpnFs TikTok: https://bit.ly/4coJ8fo X: https://bit.ly/3Opc8tf Facebook: https://bit.ly/464VA1H LinkedIn: https://bit.ly/4hH7Ri2 Website: https://bit.ly/4eLDbdU Merch: https://bit.ly/4aBpOM1 Newsletter: https://bit.ly/47ejrws Ask Gary: https://bit.ly/3PEAJuG Timestamps 00:00 Intro of Show 02:22 Role of Neurotransmitters on the Road to Happiness 03:27 Neurotransmitters on the Sense of Purpose and Community 12:24 Why Is Society Becoming Disconnected? 17:22 D. Dopamine Definition 20:29 O. Oxytocin's Role in Humans 31:04 S. Serotonin's Influence on Mood and Emotional State 40:16 E. Endorphins' Impact on Stress 43:25 Objective behind the DOSE Lab 46:50 The DOSE Effect 1:01:18 Boredom and the Lack of Sense of Purpose 1:04:21 Connect with TJ 1:05:17 What does it mean to you to be an Ultimate Human? The Ultimate Human with Gary Brecka Podcast is for general informational purposes only and does not constitute the practice of medicine, nursing or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast or materials linked from this podcast is at the user's own risk. The Content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professionals for any such conditions. Learn more about your ad choices. Visit megaphone.fm/adchoices
On episode 716 of the 40+ Fitness podcast, we're diving deep into a topic that's crucial as we age: bone health and osteoporosis. Coach Allan is joined by Dr. John Neustadt, a seasoned researcher, clinician, and author of Fracture-Proof Your Bones: A Comprehensive Guide to Osteoporosis. Dr. Neustadt breaks down the science behind why our bones are much more than just the framework of our bodies—they're living tissues connected to everything from our hormone health to our immune system. In this conversation, you'll learn why bone density tests don't tell the full story, how to truly reduce your fracture risk, and what daily choices can dramatically improve your bone health. Dr. Neustadt explores holistic approaches—highlighting how the right exercise routine and following a Mediterranean-style diet can not only strengthen your bones, but also lower your risk for heart disease, dementia, and cancer. Whether you're already concerned about osteoporosis or just want to future-proof your health, this episode is packed with actionable advice, insights on the surprising connection between chronic inflammation and bone loss, and tips on training safely and consistently as you get older. Time Stamps: 04:01 Holistic Bone Health Guide 06:41 Osteoporosis: Misplaced Focus on Testing 12:27 Serotonin's Impact on Bone Health 15:20 Early Osteoporosis Research Missteps 18:29 Bone Health and System Balance 21:07 Healthy Eating for Strong Bones 23:43 Safe, Effective, Consistent Exercise Advice 28:31 Mindset Shapes Everyday Exercise Benefits 32:08 Chronic Inflammation Destroys Health 35:02 Positive Focus for Well-Being 38:27 Medications, Fracture Risk & Solutions https://https://www.nbihealth.com/
In this Huberman Lab Essentials episode, I explore how biological rhythms and neurochemicals impact our perception of time. I describe how the body aligns with daily and seasonal light cycles to regulate hormones that influence energy, mood and motivation throughout the year. I share science-based tools to enhance focus and productivity, including strategies for structuring work intervals and optimizing the timing of exercise and daily light exposure. I also explain how neurotransmitters like dopamine and serotonin influence our perception of time and how factors such as novelty, emotion and routine impact how we experience and recall time. Read the episode show notes at hubermanlab.com. Thank you to our sponsors AGZ by AG1: https://drinkagz.com/huberman BetterHelp: https://betterhelp.com/huberman Timestamps (0:00) Time Perception (0:48) Entrainment, Circannual Rhythms & Melatonin (4:22) Circadian Rhythms, Tools: Exercise; Morning & Evening Light for Circadian Entrainment (9:01) Sponsor: AGZ by AG1 (10:30) Ultradian Cycles, Focus & Work (14:06) Time Perception, Past, Present & Future (16:21) Dopamine, Norepinephrine & Serotonin, Time Perception (18:40) Dopamine & Serotonin, Daily Fluctuations, Tool: Structuring Work, Sleep (20:23) Trauma, “Over-clocking”, Slowing Time & Emotions (24:59) Sponsor: BetterHelp (26:15) Event Perception (Fun vs Boring), Time & Memories (29:23) Novel Experiences, Places & People, Retrospective Time (31:24) Habits, Tool: Schedule Functional Units (32:59) Recap & Book Suggestion Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices
For most people, the advice is simple: stop eating after dinner to improve digestion, support deeper sleep, and boost long-term health. But as with all things in life, there are exceptions and in some cases, a small nighttime snack can actually be beneficial. On today's show we'll break down both sides of the debate and cut through the confusion to decide whether eating before bed supports or sabotages your goals. Join me on Cabral Concept 3533 as we explore whether you should (or shouldn't) eat before bed and how to personalize the answer for your own health journey. Enjoy the show, and let me know what works best for you! - - - For Everything Mentioned In Today's Show: StephenCabral.com/3533 - - - Get a FREE Copy of Dr. Cabral's Book: The Rain Barrel Effect - - - Join the Community & Get Your Questions Answered: CabralSupportGroup.com - - - Dr. Cabral's Most Popular At-Home Lab Tests: > Complete Minerals & Metals Test (Test for mineral imbalances & heavy metal toxicity) - - - > Complete Candida, Metabolic & Vitamins Test (Test for 75 biomarkers including yeast & bacterial gut overgrowth, as well as vitamin levels) - - - > Complete Stress, Mood & Metabolism Test (Discover your complete thyroid, adrenal, hormone, vitamin D & insulin levels) - - - > Complete Food Sensitivity Test (Find out your hidden food sensitivities) - - - > Complete Omega-3 & Inflammation Test (Discover your levels of inflammation related to your omega-6 to omega-3 levels) - - - Get Your Question Answered On An Upcoming HouseCall: StephenCabral.com/askcabral - - - Would You Take 30 Seconds To Rate & Review The Cabral Concept? The best way to help me spread our mission of true natural health is to pass on the good word, and I read and appreciate every review!
So the Longer You Fight, the Less You Can Focusby Mr. Twenty Twenty – Power of Imagination Podcast“I can't focus for more than a few seconds. Then my mind wanders…”I've gotten that email three times this week.Here's the deal:The longer you fight, the less you can focus.If you're in a battle of the mind…Trying to force yourself to focus…You're not manifesting…You are mentating - on a problem…Trying to eliminate a pain.Instead of giving life to a possibility.Let's Start Where Manifesting Actually BeginsNeville Goddard taught it in The Four Mighty Ones:“Wouldn't it be cool…”Wouldn't it be cool…That's the FEELING that awakens the PRODUCER.The first of the FOUR MIGHTY ONES.In my life…. I nailed….“Wouldn't it be cool.. to make great money… while doing what I love?”That's your Producer moment.Right there, you just opened the door to a possibility.There's a physiology shift that happens.You feel it in your belly and it will land in your bones.You smile. You nod.Something moves inside.That's real. That's FEELING IT REAL.Then Comes the Author MomentThe Author writes the FINAL scene.Neville says that's all he does.No movie script.No detailed storyboard.No trying to figure it out.Just a moment of:“What would imply my wish is already fulfilled?”I imagine this:YOU show up HERE with a box of cigars.“Mr. Twenty Twenty, I got something for you. Can I stop by?”Boom. That's it. That implies - our work - has blessed you.And it takes just a split secondin time.Don't Ignore The Secret DoorMost people start with pain.They try to eliminate it.But when you start there?You're trying to slay the dragon, not enter the garden.You haven't found the secret door.The secret door is always:Wouldn't it be cool…That's your entrance.That is the masterkey to the POWER OF POSSIBILITY.I'm a Tricker. Here's the Trick.Here's my sneaky secret…That guarantees YOUR success…Inside Manifesting Mastery Deluxe…Every seven days, I say:“Post an update in the group.”Not to report in. I want you…To experience the Author moment.Wouldn't it be cool…To have a really cool update?Then it happens….If you take the time - to experience…Wouldn't it be cool?Becuase…Manifesting doesn't start with pain.It starts with a spark.Wouldn't it be cool…That lights up your status chemicals.
Because You're Not Beginning Where Manifesting BeginsManifesting always begins with the power of possibility.If you try to begin anywhere else,You're not manifesting.And odds are - you're going “mental”. Most people try to make mind movies that take minutes.But their attention span? About 18 seconds.So they end up daydreaming instead of creating.Neville Goddard said:“The twinkle of an eye.”“The moment you feel a desire…”“That's when you move into its assumption.”Not 10 minutes later.Not after your meditation music.Not after clearing your chakras.Transformation happens in an instant.I can look at someone and feel that…They're full of shit.And guess what? They respond - instantly.Their body.Their emotions.Their mind.They respond to my imaginal act.“They are full of shit.”But if I take it one step further...I remember the Disciple of John from https://JoinRemarkable.comThe disciple of John helps us notice…They're just lost love.They forgot who they are.They forgot to listen with love.So they talk shit…Because they feel - like shit.So I imagine lovingly for them.And they shift- instantly.“Man's faith in God is measured by his confidence in himself.” - Neville GoddardOne Sip Simple.This is how we teach imagining.The Missing Masterkeys to REALLY feeling it real.You stop seeking solutions - your mind - loves - seeking solutions.Your soul wants to see from - love - and bring beauty into the world.Because you are how God has the adventure of a lifetime.The spirit that you are — the life-giving spirit…The soul you bring to the room…Wants to see from a state.But your humanity?It gets hooked on stories.Hooked on fixing.Hooked on proving.Hooked on arguing.When you are Mental….Take a walk.Beacause you can only walk in one direction at a time.This will focus you - in one direction if…While you walk, you…Imagine lovingly.For the people you pass.For the people who pop into your mind.Don't try to figure out what to imagine.Don't try to do it “right.”Do you see an old couple?I imagine them holding hands.Do you pass a puppy?I imagine it wiggly waggly.You see a little girl?I imagine her riding ponies or playing with posies. I don't try to figure it out.I just notice what pops in and…I give it life.And I move on.That's how you stop being mental. And that's how you discover the state of…I am the blessing!Kung Fu King & Dev's QuestionMy buddy Dev last night dove into Identity-Based Manifesting.He asks:“How do I find my Kung Fu King?”Let's nail this down:Most people try to fix their pain.Financial pain.Emotional pain.Physical pain.Pain, pain, pain.They're chasing relief.Trying to escape cortisol.But Neville teaches in The Four Mighty Ones:It begins with a possibility.“Wouldn't it be cool…”Wouldn't it be cool to do Kung Fu again like I did in my 30s?Boom. That's identity. The Kung Fu King!Once identity shows up?The Four Happy Chemicals flood your system.
In this enlightening episode, Kashif Khan, co-founder of The DNA Company, discusses the intricate connection between genetics, health and wellness. Khan shares his personal health journey and explains how he went from battling multiple chronic diseases to becoming a pioneer in genetic research. He emphasizes the importance of understanding one's genetic makeup to navigate health challenges more effectively, touching on topics such as the role of the nervous system, diet, environment and the impact of ancestral genetic expressions. Beyond this, he and Gabby discuss how social connections can actually impact your health. Overall, this conversation covers actionable insights on how to tailor lifestyle choices, optimize health and manage stress based on individual genetic profiles. Check out this insightful conversation that will inspire you to dig deeper, make changes and better understand your body's individual needs. Kashif Khan's Website: https://kashkhanofficial.com/ Follow Kashif Khan on Instagram: KashKhanOfficial For more on Gabby Instagram @GabbyReece TikTok @GabbyReeceOfficial The Gabby Reece Show Podcast on YouTube: https://www.youtube.com/@GabbyReece The Gabby Reece Show podcast is Produced by Rainbow Creative (https://www.rainbowcreative.co/) Thank You to Our Sponsors Timeline - My friends at Timeline are offering 20% off, just for my listeners. Head to timeline.com/gabby to get started. Ritual - Get 25% off your first month at ritual.com/GABBY Laird Superfood - High-quality ingredients paired with incredible taste. Use the code GABBY20 for 20% off your purchase at http://lairdsuperfood.com CHAPTERS 00:00 Understanding the Brain's Duality: Trauma vs. Gratitude 00:39 Introduction to the Guest: Kashif Khan 01:53 Kashif Khan's Personal Health Journey 02:47 The Role of Genetics in Health and Wellness 04:01 The Impact of Dopamine and Serotonin on Behavior 07:12 Genetic Traits and Their Influence on Health 12:00 The Importance of Sunlight and Circadian Biology 15:29 Cold and Heat Stress: Benefits and Adaptations 20:43 Longevity and Healthspan: The Role of Relationships 29:00 Genetic Testing and Personalized Health 34:29 Contrasting Personalities in the Workplace 35:10 Discovering Personal Traits and Leadership Styles 35:45 The Journey of Self-Discovery and Purpose 37:15 Applying Genetic Research to Real Life 38:40 The Gender Gap in Medical Research 40:26 Understanding Bioindividuality and Health 47:20 Genetic Testing and Personalized Healthcare 49:21 The Role of the Nervous System in Health 01:03:22 Epigenetics and Generational Trauma 01:06:32 Understanding Personal Identity and Survival Tools 01:07:39 Mapping the Mind and Discovering Self 01:08:59 Unlocking Superpowers and Managing Impulses 01:11:45 Invisible Factors Impacting Longevity 01:14:14 The Power of Real Food and Natural Remedies 01:17:56 Preventing Dementia and Alzheimer's 01:21:12 The Role of Genetics in Health and Performance 01:24:36 Empowerment Through Personalized Health 01:33:41 Balancing Health, Family, and Purpose Learn more about your ad choices. Visit megaphone.fm/adchoices
Show NotesIn this special live episode from the 2025 North American Congress of Clinical Toxicology (NACCT), Ryan takes you inside the conference to hear directly from the researchers themselves. Covering 11 abstracts that span high-stakes management decisions, surprising case reports, and challenges to toxicology dogma, this year's highlights feature everything from amlodipine overdoses to naturopathic misadventures, metformin-associated blindness, and more. The show kicks off with a foreword from Ryan and Dr. Jon Cole (abstract co-chair for AACT) discussing some of their favorite research from the conference. If you couldn't make it to NACCT or just want to catch up on some of the most impactful new research in our field, this episode will give you a front-row seat. Check below for links to the published abstracts, the full list of studies discussed, and timestamps for where you can hear each one.Link to published abstract manuscriptForeword with Dr. Jon Cole 10:24 #7. Is beta blocker toxicity associated with hypoglycemia?Lead author: Dr. Megan Audette, MD17:58 #237. V-A ECMO as a treatment for vasoplegic shock in amlodipine poisoning: a comparisonLead author: Dr. Daniel Tirado, MD27:59 #247. Blocked but not beaten: ECMO's role in severe amlodipine toxicity – a poison center case seriesLead author: Dr. Carlos Saldarriaga, MD28:39 #26. Amlodipine double-dose therapeutic errors reported to Poison CentersLead author: Johanne Freeman30:19 #27. Dosing on the edge: unpacking inadvertent amlodipine ingestions reported to a single poison centerLead author: Dr. Tiana Patriarca, PharmD33:44 #292. Intravenous administration of sodium zirconium cyclosilicate resulting in deathLead author: Dr. Stephen Thornton, MD Researcher interviews43:57 – #21. Quantitative analysis of amlodipine removal by plasmapheresisGuest: Dr. Keahi Horowitz, MD – Acute and Intensive Care Research Award winner48:14 – #23. Relationship between reported ingestion dose and outcome in amlodipine poisoningGuest: Dr. Colleen Cowdery, MD51:18 – #24. Management of severe amlodipine toxicity with high-dose calcium aloneGuest: Dr. Vincent Ma, MDHigh dose norepinephrine in amlodipine overdose Case report of calcium death 56:37 – #70. Iatrogenic exposure to long-acting buprenorphine injectable in an opioid-naïve patientGuest: Dr. Conor Young, MD59:52– #182. Left in the dark: a case of blindness in the setting of metformin toxicityGuest: Dr. Madison Bombard, MD61:52 – #169. Just because it's natural doesn't mean it's safe: a case of pediatric toxicity from topical and herbal remediesGuest: Dr. Aria Darling, MD64:12 – #203. Serotonin syndrome after vaping MoocahGuest: Dr. Connor Murphy, MD66:47 – #307. Intravenous ozone autohemotherapy: a retrospective observational case seriesGuest: Nicole McLarty 71:06 – #134. Do they really need n-acetylcysteine? Exploratory analysis of outcomes in patients with elevated liver function
Gravity may be the most ignored signal in human biology, and it could be the missing key to unlocking fat loss, brain optimization, and true longevity. In this episode, you'll learn how Earth's pull shapes your metabolism, mood, and resilience, and discover practical hacks to fight “gravity intolerance” so you can perform better, live longer, and upgrade every system in your body. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Dr. Brennan Spiegel, a Professor of Medicine and Public Health at UCLA, Director of Health Services Research at Cedars-Sinai, and author of Pull: How Gravity Shapes Your Body, Steadies the Mind, and Guides Our Health. A leading voice in digital health and immersive medicine, Dr. Spiegel brings decades of clinical and research experience exploring the intersection of the gut-brain axis, neuropsychology, and mind-body medicine. In this episode, he reveals why gravity influences everything from gut health to depression — and why modern medicine has largely ignored its role. His work bridges functional medicine, neuroscience, and biohacking to uncover a hidden force that shapes human performance at every level. You'll Learn: • Why gravity is the most ignored biohacking signal in human health • How gravity intolerance shows up as back pain, fatigue, obesity, and depression • The surprising connection between gravity, serotonin, and mood regulation • How weighted vests, balance boards, and proprioception training hack graviception • Why sleep optimization, posture, and fascia resilience are gravity-based health tools • How Earth's pull influences gut health, metabolism, and even consciousness You'll learn how gravity connects to obesity, back pain, blood pressure, serotonin, and even consciousness. Dave and Dr. Spiegel explore how weighted vests, balance boards, vibration, and sleep optimization can hack your body's response to gravity. This channel dives into mitochondria, neuroplasticity, fasting, ketosis, supplements, and how biohackers can apply these insights alongside tools like cold therapy, nootropics, and even Danger Coffee to build resilience and extend longevity. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday (audio-only), and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: Gravity intolerance, Graviception, Serotonin and gravity, Tensegrity fascia system, Interstitium organ discovery, Piezoelectric cell membranes, Weighted vest training health, Balance board proprioception, Inclined bed sleep therapy, Gravity and depression, Obesity as a gravity disease, Low blood pressure gravity link, Crohn's disease altitude flares, Gravity and microbiome diversity, Glymphatic drainage sleep optimization, Space travel gravity health risks, Astronaut vision loss microgravity, Vagus nerve and gravity, Collagen and gravity resilience, Barefoot running gravity mechanics Thank you to our sponsors! Zbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order. Timeline | Head to https://www.timeline.com/dave to get 20% off. Resources: • Pre-order Brennan's Book: https://a.co/d/ik2C9iB • Danger Coffee: https://dangercoffee.com/discount/dave15 • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 — Trailer 1:30 — Intro 4:14 — Gravity and Human Evolution 5:39 — Why Medicine Ignores Gravity 8:43 — Signs of Gravity Intolerance 12:18 — Training Gravity Resilience 16:46 — Gravity in Space 20:34 — Managing Gravity When Flying 23:59 — NASA's Gravity-Diet Link 26:55 — Serotonin and Gravity 37:42 — Gravity and Sleep 50:24 — Obesity as a Gravity Issue 55:39 — Movement and Balance 57:38 — Gravity-Resistant Exercises See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Dopamine. Serotonin. Endorphins. We have all heard these terms. And they shape our lives in many ways. From wine and coffee to opioids and party drugs, almost all of us use some chemicals to manipulate our lived experience. Brain chemistry shapes our self-image, too: few are those who have never wondered if their brain chemicals are "just off balance". So how accurate are the popular theories about these mythic molecules? To guide us through the topic, I'm joined by Judy Grisel—an ex-addict and a world-leading neuroscientist of addiction. We will discuss all the main elements of brain chemistry by using drugs and addictions as a window into the chemicals that flavour all of our lives. Towards the end, we also search for ways to better help those who struggle with addiction. As always, we finish with my guest's reflection on humanity.
What if you could spark your child’s motivation without nagging or bribing? In this episode of the Happy Families Podcast, Dr Justin and Kylie reveal the four “happy brain” chemicals—dopamine, serotonin, endorphins, and oxytocin—and simple daily habits that naturally boost them. Discover how to create an environment where kids feel driven to learn, calm under pressure, and connected at home. These small shifts can transform study sessions, chores, and family time—no sneaky tricks required. KEY POINTS Dopamine – The Anticipation Engine: Break big tasks into small wins to fuel progress and keep motivation high. Serotonin – The Calm Conductor: Nature time, sunlight, and slow breathing help kids reset and regulate emotions. Endorphins – The Natural Painkiller: Movement, laughter, and a dash of safe risk-taking release powerful mood boosters. Oxytocin – The Connection Catalyst: Hugs, shared meals, and positive friendships build trust and belonging. Practical take-aways: chunk chores, go barefoot on the grass, encourage physical play, and prioritise warm, consistent connection. QUOTE OF THE EPISODE “Creating the right environment isn’t manipulation—it’s giving our kids’ brains the natural fuel they need to thrive.” RESOURCES MENTIONED Brain Chemistry Hacks for Better Learning [Article] #1195 - Everything You Ever Wanted to Know About ASD, ADHD and Executive Function With Andrew Guastella [Podcast] ACTION STEPS FOR PARENTS Chunk It Down: Turn daunting tasks into bite-sized steps for instant dopamine rewards. Get Outside Daily: Ten minutes of green space or blue sky calms the nervous system. Move and Laugh: Family dance party, backyard games, or silly jokes for a natural endorphin hit. Prioritise Connection: Schedule unhurried meals or bedtime stories to release oxytocin and strengthen bonds. Find us on Facebook Subscribe to the Happy Families newsletterSee omnystudio.com/listener for privacy information.
Send us a textHow nutrition and medications impact mitochondrial health.Wide release date: October 1, 2025.Episode Summary: Dr. Chris Masterjohn talks about the intricate relationships between nutrition, prescription drugs, and mitochondrial health, discussing how molecules like acetaminophen and SSRIs affect the body beyond their intended purposes, particularly impacting inflammation and energy metabolism. The discussion gets into the broader implications of serotonin outside the brain, the side effects of commonly used medications, and the importance of personalized nutritional strategies to optimize mitochondrial function.About the guest: Chris Masterjohn, PhD holds a doctorate in nutritional sciences and is a co-founder of Mitome, a company focused on mitochondrial testing to optimize cellular energy production.Discussion Points:Acetaminophen & Inflammation: Acetaminophen (Tylenol) may contribute to chronic low-grade inflammation by blocking both the initiation and resolution of inflammation, potentially linked to health issues like autism when used during pregnancy.Serotonin's Role Beyond the Brain: Approximately 95% of serotonin is found in the gut, regulating motility, with SSRIs causing side effects like nausea due to increased extracellular serotonin.SSRIs & Mitochondrial Function: SSRIs disrupt serotonin uptake into cells, reducing mitochondrial melatonin production, which impairs the body's ability to handle hypoxic stress and produce ATP efficiently.Statins & Mitochondrial Impact: Statins, used to lower cholesterol, inhibit the mevalonate pathway, affecting not just cholesterol but also CoQ10 and vitamin K2, crucial for mitochondrial function, potentially leading to side effects like myopathy.Mitochondrial Testing with Mitome: Masterjohn's company, Mitome, uses cheek swab tests to measure mitochondrial respiratory chain activity, providing personalized dietary and lifestyle recommendations to optimize cellular energy production.Nutrition & Mental Health: Masterjohn shares his personal experience of severe mental health issues on a vegan diet, which improved dramatically with a nutrient-dense diet rich in organ meats, highlighting individual nutritional needs.Energy Metabolism's Universal Role: Mitochondrial ATP production governs everything from daily energy levels to long-term health, with personalized testing helping identify and address specific bottlenecks.*Not medical advice.Support the showAffiliates: Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they're hiding, with this easy-to-use mobile app. KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime) Lumen device to optimize your metabolism for weight loss or athletic performance. Code MIND for 10% off SiPhox Health—Affordable at-home blood testing. Key health markers, visualized & explained. Code TRIKOMES for a 20% discount. For all the ways you can support my efforts
Sports Daily Full Show 29 September 2025
In this episode, we review the high-yield topic Selective Serotonin Reuptake Inhibitors (SSRIs) from the Psychiatry section at Medbullets.comFollow Medbullets on social media:Facebook: www.facebook.com/medbulletsInstagram: www.instagram.com/medbulletsofficialTwitter: www.twitter.com/medbulletsLinkedin: https://www.linkedin.com/company/medbullets
Your gut isn't just about digestion—it's a powerful command center for your mood, immune health, and even how your brain works. In this episode, Dr. Odell discusses the gut-brain connection and explores how this two-way communication system impacts everything from stress resilience to emotional well-being. He'll uncover the fascinating science of the enteric nervous system (your “second brain”), the vagus nerve superhighway, and the trillions of microbes living inside you that produce neurotransmitters like serotonin, dopamine, and GABA. You'll learn how gut health influences inflammation, stress hormones, mental clarity, and mood—and what happens when the gut ecosystem falls out of balance. Most importantly, you'll discover practical, evidence-based strategies to heal from the inside out: from gut-friendly nutrition and probiotics to lifestyle practices that calm both body and mind. If you've ever wondered why bloating, brain fog, anxiety, or low mood might all be connected, this episode will give you the clarity—and the tools—to start shifting your health.
In this episode, we sit down with Dr. Tyler Panzner, a PhD scientist specializing in genetic health optimization, to discuss the most common mistakes people make with supplements. He emphasizes the importance of integrating both genetic data and blood work to create personalized wellness strategies, noting that while genetics reveal potential vulnerabilities, lifestyle and epigenetics determine how those genes express. Dr. Panzner also highlights the significance of methylation genes (like COMT), which impact neurotransmitters and detoxification, touches on the role of GLP-1s, as well as how psychedelics can be helpful tools. Overall, the conversation reinforces the value of precision health—leveraging genetic insights alongside lifestyle factors to make smarter, safer choices in supplementation.Dr. Tyler Panzner is a Ph.D. scientist with a deep background in pharmacology, cancer, neuroscience, and inflammation research. His passion for how different substances affect the body has been lifelong, but about seven years ago, he found his true calling in genetics and personalized medicine. Since then, he's been on a mission to create personalized vitamin, supplement, and lifestyle protocols tailored to each individual's unique biology.His approach is all about understanding what your cells truly need and uncovering which vitamins, supplements, or foods might not be a good match for your genetic makeup. He firmly believes that by aligning your habits with your genes, not only can you feel your best every day, but you can also lower your risk for chronic diseases in the long run. His practice focuses on genetically optimizing health, helping people unlock their body's full potential to truly thrive.Dr. Panzner sees a massive lack in supplement education across all sectors of healthcare, which shows up as unnecessary suffering as people feel worse due to the wrong supplement recommendations. He is driven to educate both practitioners for their practice and consumers in the supplement aisle of the store so they can make more informed decisions regarding their or their patient's supplementation strategies.SHOW NOTES:0:39 Welcome to the podcast!3:31 Dr. Tyler Panzner's Bio4:03 Welcome him to the show!5:05 This biggest mistake with supplementation9:31 Iron chelation & anemia12:35 CBD & Serotonin blockers15:51 GLP-1s: the good & bad24:25 Genetics vs lifestyle26:37 Cross-referencing with lab work 31:11 Histamine issues35:59 *ALIGN MAT*37:36 Methylation genes44:30 MTHFR52:46 Genetic testing57:17 Alzheimer's & APOE1:00:58 Psychedelics & genetics1:11:58 Natural ways to raise BDNF1:12:41 His finale piece of advice1:15:34 Where to find him1:16:16 Thanks for tuning in!RESOURCES:https://drtylerpanzner.com/InstagramFacebookLinkedInYouTubeTikTokAlign Mat - $250 off with code: BIOHACKERBABESEp 291: Align Mat with Alyssa & MikeSupport this podcast at — https://redcircle.com/biohacker-babes-podcast/donationsAdvertising Inquiries: https://redcircle.com/brands
Fitness mit M.A.R.K. — Dein Nackt Gut Aussehen Podcast übers Abnehmen, Muskelaufbau und Motivation
„Ich müsste jetzt eigentlich trainieren …“, denkst Du, und zack, scrollst Du schon wieder. Mentale Erschöpfung killt gute Vorsätze schneller als jede Tüte Chips. Die Selbstmanagement‑Expertin Cordula Nussbaum zeigt Dir in dieser Folge, wie Du mit 1‑Minuten‑Strategien den Kopf frei bekommst – damit Ernährung, Training und Erholung endlich im Alltag funktionieren.____________*WERBUNG: Infos zum Werbepartner dieser Folge und allen weiteren Werbepartnern findest Du hier.____________Cordula Nussbaum ist Psychologin, Coach, SPIEGEL-Bestsellerautorin und eine der prägenden Stimmen für kreativ‑chaotisches Zeit‑ und Selbstmanagement im deutschsprachigen Raum.In ihrem neuen Buch „Die 1‑Minuten‑Strategie gegen mentale Erschöpfung*“ zeigt sie, wie kleine Veränderungen Dir die Power in einen chaotischen Alltag bringen, sodass Du gesunde Routinen für Training, Ernährung und Erholung aufbauen kannst.Themen dieser Folge sind, unter anderem:Mentale Erschöpfung: Was Dein Handy, To-Do-Listen, Reizüberflutung und Dehydrierung gemeinsam haben.Kleine Strategien und Hebel für Deinen Alltag, die Dir das Dranbleiben erleichtern können – in einer Minute oder weniger.Organisiert oder kreativer Chaot? Wie Du herausfindest, welche Strategien für Dich passen (und welche nicht).Alltagshelfer statt Energievampire: Was Du tun kannst, um Deinen Alltag energetisierend statt ermüdend zu gestalten.Viel Spaß beim Hören!
Estrogen accumulates in your tissues even when blood tests show low levels, leading to misdiagnosis and ineffective treatment Hair and nail testing reveal long-term patterns of hormone and mineral buildup, offering clearer insight into chronic symptoms like fatigue, infertility, and fluid retention High prolactin levels often signal hidden estrogen activity and are especially important to monitor if your thyroid function is low Vegetable oils, plastics, and many common household products contain compounds that either mimic estrogen or promote estrogen dominance by disrupting thyroid function, impairing detox pathways, and driving chronic inflammation Natural progesterone and liver-supportive strategies like collagen-rich foods help reduce your tissue estrogen burden and restore balance
Dr. Hoffman continues his conversation with Martha Carlin, CEO and founder of the Bio Collective.
Martha Carlin, CEO and founder of the Bio Collective, details the significant influence of the microbiome on overall health. Martha discusses her unconventional path from accounting to microbiome research, sparked by her husband's Parkinson's diagnosis. Together, they explore the complex connections between gut health and diseases like Parkinson's, autism, and even Alzheimer's. Martha sheds light on groundbreaking research funded by NIH grants, the potential of machine learning and AI in understanding microbiome patterns, and the future prospects of personalized probiotics. Practical advice on maintaining a healthy microbiome, the impact of diet and exercise, and the intriguing intersections between gut health, neurochemistry, and systemic diseases are highlighted. The discussion also covers challenges in integrating microbiome research into clinical practice and potential future therapies.
Dr. Rubén Ancona Bolaños is a Metabolic Health Practitioner from Mexico who has been having incredible success using ketogenic therapies to help his patients reclaim their metabolic health! He has a special interest in the interplay between diet, metabolic health, and hormones like dopamine and serotonin. From this episode… “One of my hypotheses is that insulin resistance could start at a young age — with dopamine resistance in the brain's reward center.” “We need to stop seeing the body and the brain as separate—hormones affect the brain, and neurotransmitters affect the body.” “Kids today are constantly hyper-stimulated, always releasing dopamine, which desensitizes their brain's reward system and raises their threshold for feeling pleasure.” In this episode, Drs. Tro and Rubén talk about… (00:00) Intro (02:02) How Dr. Rubén first became interested in metabolic health (22:07) How addiction plays into metabolic dysfunction (27:07) How Dr. Rubén helps his patients reclaim their metabolic health (29:05) Dopamine, serotonin, oxytocin, and insulin resistance (53:39) Gut health and antibiotics (56:47) Dopamine detoxing (01:03:29) Dr. Rubén's clinical approach (01:08:50) How to keep patients motivated For more information, please see the links below. Thank you for listening! Links: Please consider supporting us on Patreon: https://www.lowcarbmd.com/ Dr. Rubén Ancona Bolaños: IG: https://www.instagram.com/ranconabmd/?hl=en Dr. Brian Lenzkes: Website: https://arizonametabolichealth.com/ Twitter: https://twitter.com/BrianLenzkes?ref_src=twsrc^google|twcamp^serp|twgr^author Dr. Tro Kalayjian: Website: https://www.doctortro.com/ Twitter: https://twitter.com/DoctorTro IG: https://www.instagram.com/doctortro/ Toward Health App Join a growing community of individuals who are improving their metabolic health; together. Get started at your own pace with a self-guided curriculum developed by Dr. Tro and his care team, community chat, weekly meetings, courses, challenges, message boards and more. Apple: https://apps.apple.com/us/app/doctor-tro/id1588693888 Google: https://play.google.com/store/apps/details?id=uk.co.disciplemedia.doctortro&hl=en_US&gl=US Learn more: https://doctortro.com/community/
In Episode 29 of The Luke Coutinho Show, Luke dives deep into the fascinating world of serotonin, the “feel-good” neurotransmitter that does much more than just regulate your mood.Here's what you will explore in this episode:The powerful role of serotonin in mood, digestion, appetite, memory, and sleep.How serotonin is directly linked to melatonin production and your circadian rhythm.Signs of low serotonin such as anxiety, irritability, sleep issues, and carb cravings.Natural ways to boost serotonin with tryptophan-rich foods paired with healthy carbs.Lifestyle practices like exercise, sunlight, meditation, probiotics, and visualization that support serotonin naturally.Why supplements like 5-HTP and melatonin should be approached with caution.And much more…
In his appearance on Tin Foil Hat with Sam Tripoli, Christian Yordanov challenges the mainstream narrative around serotonin, arguing that it is not the “happy chemical” it has been marketed as, but rather a product of pharmaceutical propaganda. He explains that serotonin can actually cause harm in the body, potentially contributing to inflammation, disease, and long-term health problems. Christian links the widespread use of SSRIs to darker agendas, referencing MK-ULTRA mind control programs and the idea of a population dulled into compliance, often referred to as “NPCs.” He also suggests that manipulating serotonin is part of a broader depopulation agenda, where these drugs gradually undermine both mental and physical health. More controversially, he claims that serotonin-based medications may be feeding the cancer industry, creating a long-term dependency on treatments that ultimately serve pharmaceutical profits rather than public well-being. Please check out Christian Yordanov's Book: How to Actually Live Longer, Vol.1: https://amzn.to/3OnZJGl Please subscribe to the new Tin Foil Hat youtube channel: https://www.youtube.com/@TinFoilHatYoutube Please check out Sam Tripoli's 3rd Crowd Work Special "Barbecued: Live From Kansas City" on Sept 20th! https://www.youtube.com/watch?v=bwVX5MkcYR0 Check out Sam Tripoli new crowd work special "Black Crack Robots" now for free. https://youtu.be/_FKugOeYaLc Check out Sam Tripoli's 2nd New Crowd Work Special “Potty Mouth” on YouTube for free. https://www.youtube.com/watch?v=22j3Ds5ArjM Grab your copy of the 2nd issue of the Chaos Twins now and join the Army Of Chaos: https://bit.ly/415fDfY Check out Sam "DoomScrollin with Sam Tripoli and Midnight Mike" Every Tuesday At 4pm pst on Youtube, X Twitter, Rumble and Rokfin! Join the WolfPack at Wise Wolf Gold and Silver and start hedging your financial position by investing in precious metals now! Go to samtripoli.gold and use the promo code "TinFoil" and we thank Tony for supporting our show. CopyMyCrypto.com: The ‘Copy my Crypto' membership site shows you the coins that the youtuber ‘James McMahon' personally holds - and allows you to copy him. So if you'd like to join the 1300 members who copy James, then stop what you're doing and head over to: CopyMyCrypto.com/TFH You'll not only find proof of everything I've said - but my listeners get full access for just $1 LiveLongerFormula.com: Check out LiveLongerFormula.com/sam — Christian is a longevity author and functional health expert who helps you fix your gut, detox, boost testosterone, and sleep better so you can thrive, not just survive. Watch his free masterclass on the 7 Deadly Health Fads, and if it clicks, book a free Metabolic Function Assessment to get to the root of your health issues. Want to see Sam Tripoli live? Get tickets at SamTripoli.com: Kansas City, Mo: Headlining The Comedy Club of Kansas City August 28th-30th https://www.thecomedyclubkc.com/events/114717 Chicago: Headlining The Comedy Bar Sept 12th-13th https://www.eventbrite.com/cc/september-12-13-sam-tripoli-4497173 Tulsa, Ok: Tin Foil Hat Comedy Is Headlining the Bricktown Comedy Club on Oct 10th https://bricktowntulsa.com/shows/310746 Oklahoma City, Ok: Tin Foil Hat Comedy Is Headlining the Bricktown Comedy Club on Oct 11th https://www.bricktowncomedy.com/events/112032 Austin, Tx: Headlining The Fat Man At Comedy Mothership Oct 17th-19th https://samtripoli.com/events/?paged=2 Las Vegas, NV: Tin Foil Hat Comedy Live At The Virgin Hotel Nov 21st https://www.etix.com/ticket/p/95279813/tin-foil-hat-comedy-with-sam-tripoli-and-eddie-bravo-las-vegas-24-oxford Minneapolis: Headlining The House Of Comedy Dec 11th-13th https://samtripoli.com/events/?paged=3 Morris Plains, NJ: New Year's Eve At The Dojo Of Comedy Dec 31st https://www.tiffscomedy.com/events/121228 Please check Christian Yordanov's internet: Website: https://christianyordanov.com/ Book: How to Actually Live Longer, Vol.1: https://amzn.to/3OnZJGl Please check out Sam Tripoli's internet: Linktree: https://linktr.ee/samtripoli Please Follow Sam Tripoli's Stand Up Youtube Page: https://www.youtube.com/@SamTripoliComedy Please Follow Sam Tripoli's Comedy Instagram: https://www.instagram.com/samtripolicomedy/ Please Follow Sam Tripoli's Podcast Clip Instagram: https://www.instagram.com/samtripolispodcastclips/ Thank you to our sponsors: Cornbread Hemp: If you're looking for a healthier way to enjoy a carefree moment, you have to give Cornbread Hemp a try! They've created the first-ever USDA Organic THC gummy that's 100% legal. As a special offer for Tin Foil Hat listeners, you can get 30% off your first order! Just visit cornbreadhemp.com/TinFoil and use promo code TinFoil at checkout. Again that's cornbreadhemp.com/TinFoil and use code TinFoil for 30% off your first order. Cheers to a healthier happy hour! Blue Chew: Make life easier by getting harder and discover your options at BlueChew.com! And we've got a special deal for our listeners: Try your first month of BlueChew FREE when you use promo code TINFOIL -- just pay $5 shipping. That's promo code TINFOIL. Visit BlueChew.com for more details and important safety information, and we thank BlueChew forsponsoring the podcast.
In this episode of Raising Serotonin, I sat down with Lindsey, The Holistic Mama, to have a real conversation about what it actually means to live holistically—without the fluff, without the quick-fix promises, and without feeling like you have to do all the things to be healthy. Lindsey opens up about her own journey and the shifts that helped her find balance in mind, body, and spirit.We dig into the power of being present as a parent, the role supplements can play in supporting mental well-being, and the small-but-mighty habits that truly move the needle—like hydration and listening to your body's cues. We discuss:-Why chasing quick fixes is costing you more than you think -The hydration tip that actually works (and it's way simpler than you think) -How to know when your body is saying “slow down” — and what to do about itIf you've ever felt stuck chasing the next “health hack” or overwhelmed by wellness trends, this episode will help you slow down, tune in, and realize that caring for yourself doesn't have to be complicated.Follow and Connect with Lindsey on Instagram FOLLOW RAISING SEROTONIN ON INSTAGRAM HERE SIGN UP FOR THE FREE RAISING SEROTONIN NEWSLETTER HERE
Real Life Pharmacology - Pharmacology Education for Health Care Professionals
Vilazodone (brand name Viibryd) is an antidepressant with a unique pharmacologic profile compared to most other agents in the SSRI class. While not a first-line choice for every patient, understanding its mechanism, adverse effects, and interaction profile is essential for optimizing therapy and preventing downstream prescribing problems. Mechanism of ActionVilazodone is classified as a selective serotonin reuptake inhibitor (SSRI) and a partial agonist at the 5-HT1A receptor. The SSRI activity increases synaptic serotonin by blocking the serotonin transporter, while partial agonism at 5-HT1A receptors may contribute to antidepressant effects and potentially reduce certain SSRI-associated adverse effects (though clinical evidence for this benefit is mixed). Adverse Effects GI effects – diarrhea, nausea, and vomiting are frequent early in therapy. Taking the medication with food can help minimize these. Insomnia – often dose-related; morning dosing may help. Sexual dysfunction – may be slightly lower than with some SSRIs but still present. Serotonin syndrome – rare but serious, particularly if combined with other serotonergic drugs. Discontinuation syndrome – abrupt cessation can lead to dizziness, irritability, and flu-like symptoms. Drug InteractionsVilazodone is primarily metabolized by CYP3A4. This means: CYP3A4 inhibitors (e.g., ketoconazole, clarithromycin, ritonavir) can increase vilazodone concentrations, potentially worsening side effects—dose reductions may be required. CYP3A4 inducers (e.g., carbamazepine, rifampin, St. John's Wort) can lower drug levels, reducing effectiveness. Other serotonergic agents (e.g., triptans, SNRIs, MAOIs, tramadol, linezolid) increase the risk of serotonin syndrome. Antiplatelets and anticoagulants – SSRIs can impair platelet aggregation, increasing bleeding risk when combined with aspirin, NSAIDs, or warfarin. Prescribing Cascade ExamplesVilazodone's adverse effects can easily lead to unnecessary prescriptions if side effects aren't recognized: GI upset → Acid suppression therapy – Diarrhea or nausea prompts the addition of proton pump inhibitors or antiemetics, instead of adjusting vilazodone dose or timing. Insomnia → Hypnotic initiation – Trouble sleeping results in adding zolpidem or trazodone, without reassessing morning dosing or vilazodone's role. Sexual dysfunction → PDE5 inhibitor prescription – Erectile dysfunction leads to sildenafil use, when the root cause is vilazodone's serotonergic activity. Vilazodone's combination of SSRI and 5-HT1A partial agonist activity makes it somewhat distinct, but its side effect profile and interactions require the same careful monitoring as other antidepressants. Healthcare professionals can play a key role in catching early signs of adverse effects, preventing prescribing cascades, and ensuring drug–drug interactions are managed appropriately.
In this episode, I'm joined by Dr. Scott Sherr, a board-certified internal medicine doctor and expert in integrative and hyperbaric medicine. He's shining a light on a little-known brain chemical called GABA — often described as your brain's “off switch.”Dr. Sherr believes GABA deficiency is one of the most overlooked drivers of mental fatigue, stress, and sleep issues today. And more importantly, he shares powerful, practical ways to support GABA naturally — beyond just popping supplements. We're talking cutting-edge tools like medicinal mushrooms (a.k.a. fungiceuticals), targeted lifestyle shifts, and more.For full show notes and transcript: https://drgundry.com/dr-scott-sherrThank you to our sponsors! Check them out: Make the swap to non-toxic cookware. Get 10% off sitewide on nontoxic cookware at fromourplace.com using the code GUNDRY.Visit Sunlighten.com and mention DrGundry when you fill out the get-pricing form and save up to $600 on your purchaseSunlightenVisit Juvent.com/GUNDRY and use code GUNDRY at checkout to get an extra $300 off your Juvent Micro-Impact Platform.Save money. Get a quote today at Progressive.com.Go to timelinenutrition.com/GUNDRY to get 10% off your first order of Mitopure.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
In this Huberman Lab Essentials episode, my guest is Dr. Matthew Johnson, PhD, a senior researcher for the Center of Excellence for Psilocybin Research and Treatment at Sheppard Pratt's Institute for Advanced Diagnostics and Therapeutics. We explore the science and therapeutic potential of psychedelic medicine, including psilocybin, MDMA and LSD. We discuss how these substances can profoundly alter perception and self-identity, providing long-lasting relief from depression, addiction and trauma when used in controlled clinical settings. We also discuss microdosing and emerging research on psychedelics' potential to support recovery from neurological injuries. Read the episode show notes at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman David: https://davidprotein.com/huberman BetterHelp: https://betterhelp.com/huberman Timestamps 00:00:00 Matthew Johnson; Psychedelics 00:01:44 Different Classes of Psychedelics 00:04:33 Psychedelics & Altering Models 00:06:18 Sponsor: David 00:07:33 LSD, Psylocibin & Serotonin 00:09:55 Psychedelic Clinical Trials 00:13:40 Therapy, Trust, Psychedelics 00:16:47 Letting Go & Psychedelic Experience, Self-Representation, Lasting Changes 00:22:31 Sponsors: AG1 & BetterHelp 00:25:26 MDMA, Dopamine & Serotonin; Bad Trips & Transcendental Experience 00:28:49 Dangers of Psychedelics 00:31:11 Microdosing Psychedelics, Antidepressant 00:35:27 Head Injuries, Psychedelics, Depression 00:38:29 Acknowledgements Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices