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On this episode of Vitality Radio, Jared breaks down everything you need to know about the Full Moon Parasite Cleanse—why it works, when to do it, and how to do it safely and effectively using CellCore's Para Kit and other supportive supplements. He explores the scientific, historical, and energetic connections between the lunar cycle and parasite activity, including how serotonin, melatonin, and the circadian rhythm influence cleansing outcomes. Jared discusses symptoms that may suggest a hidden parasite burden, explains the benefits of syncing your cleanse with the full moon, and shares practical steps to open drainage pathways to ensure the elimination of toxins during your cleanse.Products:CellCore Para KitPara 4Drainage ActivatorRegulari-TBowel MoverLiverVitalityAdvanced TudcaUnbound TudcaAdditional Information:#536: CellCore ParaKit Explained: How Each Product Supports Parasite Cleansing#432: Your Parasite Cleansing User's Guide#359: Comprehensive Detoxification of Parasites, Lyme, and Other Toxins With Dr. Todd Watts of CellCore BiosciencesVisit the podcast website here: VitalityRadio.comYou can follow @vitalitynutritionbountiful and @vitalityradio on Instagram, or Vitality Radio and Vitality Nutrition on Facebook. Join us also in the Vitality Radio Podcast Listener Community on Facebook. Shop the products that Jared mentions at vitalitynutrition.com. Let us know your thoughts about this episode using the hashtag #vitalityradio and please rate and review us on Apple Podcasts. Thank you!Just a reminder that this podcast is for educational purposes only. The FDA has not evaluated the podcast. The information is not intended to diagnose, treat, cure, or prevent any disease. The advice given is not intended to replace the advice of your medical professional.
Neurobiologist Jamie Zeitzer is an expert on sleep – or, more accurately, an expert on why so many can't sleep. He notes that, ironically, it's often anxiety about sleep that prevents good sleep. In short, we lose sleep over lost sleep. Wearables and other tools can help but only to a point, and medications do not induce natural sleep. Instead, he counsels consistent routines, less stimulation at bedtime, and cognitive behavioral therapy to reduce worry about insomnia. Unfortunately, you can't work harder to get better sleep – you have to learn to relax, Zeitzer tells host Russ Altman on this episode of Stanford Engineering's The Future of Everything podcast.Have a question for Russ? Send it our way in writing or via voice memo, and it might be featured on an upcoming episode. Please introduce yourself, let us know where you're listening from, and share your question. You can send questions to thefutureofeverything@stanford.edu.Episode Reference Links:Stanford Profile: Jamie ZeitzerConnect With Us:Episode Transcripts >>> The Future of Everything WebsiteConnect with Russ >>> Threads / Bluesky / MastodonConnect with School of Engineering >>> Twitter/X / Instagram / LinkedIn / FacebookChapters:(00:00:00) IntroductionRuss Altman introduces guest Jamie Zeitzer, professor of psychiatry and behavioral sciences at Stanford University.(00:03:12) Understanding Circadian RhythmsHow the biological clock regulates sleep and other body functions.(00:04:57) The Mystery of Sleep's PurposeWhat is still unknown about the fundamental need for sleep.(00:06:00) Light and the Circadian ClockThe impact light exposure has on the body's internal sleep timing.(00:08:13) Day and Night Light ContrastThe importance of creating a light-dark contrast for healthy rhythms.(00:11:18) Phones, Screens, and the Blue LightWhether blue light from screen use affects sleep quality.(00:13:49) Defining and Diagnosing Sleep ProblemsHow stress and over-focus on sleep quality worsen insomnia.(00:16:02) Sleep Anxiety and WearablesThe psychological downsides of sleep data from tracking devices.(00:17:14) CBT-I and Rethinking InsomniaMentally reframing sleep with cognitive behavioral therapy for insomnia.(00:21:21) Desynchronized Sleep PatternsStudying student sleep patterns to separate circadian vs. sleep effects.(00:23:49) Shift Work and Circadian MisalignmentThe difficulty of re-aligning circadian clocks in rotating shifts.(00:26:26) Effectiveness of Sleep MedicationsThe various drugs used to promote sleep and their pros and cons.(00:29:46) Circadian “Sleep Cliff” and MelatoninThe brain's “wake zone” before sleep and the limited effects of melatonin.(00:32:52) Do's & Don'ts for Better SleepAdvice for those looking to improve their sleep quality.(00:34:55) Alcohol and Caffeine EffectsHow metabolism influences the effects of alcohol and caffeine on sleep.(00:37:24) Conclusion Connect With Us:Episode Transcripts >>> The Future of Everything WebsiteConnect with Russ >>> Threads / Bluesky / MastodonConnect with School of Engineering >>>Twitter/X / Instagram / LinkedIn / Facebook
The FIT Collective Genetic Insights Series – Episode 1Understanding Genetics, Stress, & Weight with Dr. Ali NovitskyDr. Ali Novitsky, board-certified in obesity medicine, kicks off a new series on how genetics influence health—especially stress responses and weight regulation. She opens with a personal story: during college, despite eating well and exercising, she gained 20 pounds in three months. Genetic testing later revealed a variant in her cortisol receptor gene, causing her body to release excess cortisol under stress—leading to high blood sugar, insulin resistance, and ultimately, weight gain.Cortisol plays a central role in stress response and metabolism. While helpful in short bursts, chronic elevation from ongoing stress can disrupt insulin function, making weight loss more difficult for those with specific genetic variants. For Dr. Novitsky, managing stress—not restricting calories or increasing workouts—was the key to reversing her weight gain.About 30% of people carry this cortisol receptor variant. In her 2022 genetics cohort, 80% tested positive. This highlights the power of personalized health strategies rooted in understanding one's unique genetic makeup.Dr. Novitsky uses Genomind's Mental Health Map, a genetic test offering insight into stress, mood, and focus. One critical gene it reports on is COMT, which affects dopamine breakdown. Individuals with the MetMet variant retain more dopamine—great for focus, but often sensitive to stress. Those with ValVal clear dopamine quickly, leading to impulsivity and a higher likelihood of ADHD.Another important factor is BDNF (brain-derived neurotrophic factor), a gene linked to memory, cognition, and mood. Those with a BDNF variant often need regular exercise to optimize brain health and emotional balance.The takeaway? Health isn't one-size-fits-all. For some, gentle exercise, high-quality sleep, and stress reduction may be far more effective than intense workouts or calorie restriction. Dr. Novitsky's approach integrates genetic awareness into actionable wellness strategies.She also introduces her four-week genetics program, which includes one-time testing, personalized supplement recommendations, and coaching based on individual results. Participants receive a lifelong health blueprint.Future episodes will explore the genetics of eating behaviors, including cravings and satiety. Listeners are encouraged to tune in and learn how DNA influences decisions, habits, and long-term health.Timestamps00:00:00 - Introduction and Personal Story00:01:00 - Understanding Cortisol and Stress00:04:00 - Genetic Testing Insights00:05:30 - Cortisol and Weight Management00:08:00 - COMT Variants and Dopamine00:10:00 - Dopamine Receptor Genes00:11:00 - Strategies for Managing Genetics00:12:00 - Genetics Program Announcement00:13:00 - Custom Recommendations Based on Genetics00:15:00 - The Role of Serotonin and Oxytocin00:16:00 - Genetic Influences on Eating Behaviors00:18:00 - Stress Response and Emotional Eating00:20:00 - The Importance of Awareness00:22:00 - BDNF and Exercise00:23:00 - Micro-Dosed Lithium and Mood00:24:00 - Genetic Predispositions to Worry00:25:00 - Empowerment Through Genetic Awareness00:26:00 - Preview of Next Episode on Eating Genetics00:27:00 - Enrollment for Genetics Program00:28:00 - Closing RemarksWork with Dr. Ali• Beginner Strength Training Program – 12 months for only $199! Enroll TODAY• Total Fitness Program – A 12-month mind-body experience. Enroll HERE• The Fit Collective® x InBody USA/Canada – Get 15% off select models. Click HERE
Ever stared at your to-do list and felt like it was staring back, daring you to make the first move? You're not lazy. Your brain's just doing what it was built to do: avoid discomfort, conserve energy, and protect you from anything that feels even slightly threatening, like starting that massive project you've been putting off for months. In this episode, I break down one of the simplest yet most effective ways to bypass your brain's panic button and finally get started: The 5 Minute Rule.For more go to: www.scottmlynch.comLevel up your life by joining my Patreon where you'll get exclusive content every week and more badass offerings (rips t-shirt in half, Hulk Hogan style, and runs around the room). And/or…Unlock practical and tactical insights on how to master your mindset and optimize your happiness directly to your inbox.If you're a glutton for punishment and want more swift kicks in the mind follow me on social:InstagramYouTubeLeave a review and tell me how I suck so I can stop doing that or you can also tell me about things you like. I'd be okay with that, too.Produced by ya boi.Past guests on The Motivated Mind include Chris Voss, Captain Sandy, Dr. Chris Palmer, Joey Thurman, Jason Harris, Koshin Paley Ellison, Rudy Mawer, Molly Fletcher, Kristen Butler, Hasard Lee, Natasha Graziano, David Hauser, Cheryl Hunter, Michael Brandt, Heather Moyse, Tim Shriver, and Alan Stein, Jr.
Brandon Eisenlauer, aka @BiohackingUThe Bodybuilding-friendly HRT Clinic - Get professional medical guidance on peptides AND optimizing your health as a man or bodybuilder:[ Pharma Test, IGF1, Tesamorelin, Glutathione, BPC, Semaglutide, Var troche, etc]https://transcendcompany.com/patient-intake-form/?ls=Nyle+NaygaWatch it: https://www.youtube.com/watch?v=6Ihq4tIzyS8&t=5618sRP Hypertrophy Training App: rpstrength.com/nylePlease share this episode if you liked it. To support the podcast, the best cost-free way is to subscribe and please rate the podcast 5* wherever you find your podcasts. Thanks for watching.To be part of any Q&A, follow trensparentpodcast or nylenayga on instagram and watch for Q&A prompts on the story https://www.instagram.com/trensparentpodcast/Huge Supplements (Protein, Pre, Defend Cycle Support, Utilize GDA, Vital, Astragalus, Citrus Bergamot): https://www.hugesupplements.com/discount/NYLESupport code 'NYLE' 10% off - proceeds go towards upgrading content productionYoungLA Clothes: https://www.youngla.com/discount/nyleCode ‘NYLE' to support the podcastLet's chat about the Podcast:Instagram: https://www.instagram.com/trensparentpodcast/TikTok: https://www.tiktok.com/@transparentpodcastPersonalized Bodybuilding Program: https://www.nylenaygafitness.comTimestamps:00:00 – Intro08:28 – Neuro-toxicity of popular PEDs (19-nors, Tren, etc.)11:42 – Brain-basics: Neuro-steroid support16:18 – Dopaminergic Life & Consequences21:32 – Real Risk of Bodybuilding, Rest & The Right Way27:04 – Managing Mental Stress: Meditation & Mindful Break38:30 – Gen Z, Motivation Gaps & “Just Go Live Life”41:17 – Independence & Growth42:46 – Psychedelics & Neuroplasticity43:45 – Hustle Culture vs Balance46:40 – Cultural & Political Extremes48:40 – Finding Balance in Bodybuilding52:19 – Conscientious Growth53:50 – Brain Protection Strategies57:01 – Serotonin & SSRI Benefits58:33 – Cholinergic, Sleep Support & GABA System1:03:30 – SSRIs Stigma & Pharma Bias1:12:45 – Best Cycle Principles1:19:38 – Pharmacology Caveats & Nuance1:25:25 – Finding Reasons Is Hard & Adaptation1:27:52 – Mitochondrial & Estrogenic Peptides1:36:14 – Stimulant Cycling Strategy & Risks1:47:10 – Injectable Amino Blends1:52:17 – Peptide Safety & Cancer1:57:36 – Skin Health & Peptides1:59:46 – The Final Question
To effectively unwind from the demands of modern life, we can tap into our body's internal chemistry. Overcoming the fatigue induced by constant technological stimulation is achievable by recognizing our need for rebalancing and actively changing our habits. The solution lies in getting a daily dose of nature, whole foods, physical exercise, and minimizing screen time.To introduce practices that activate and boost our natural stress defence, Harvesting Happiness Podcast Host Lisa Cypers Kamen speaks with neuroscientist, best-selling author, and founder of The DOSE Lab, TJ Power.TJ empowers us with brain boosting tips from his book, The DOSE Effect: Optimize Your Brain and Body by Boosting Your Dopamine, Oxytocin, Serotonin, and Endorphins.This episode is proudly sponsored by:Buffy Bedding — Offers a new standard of rest and nightly self-care ritual. Visit buffy.co to get 20% off your first order using promo code HHTR.Quince—Offers high-quality essentials, home decor, and furnishings at radically low prices.Visit Quince.com/hhtr for free shipping on your order and three hundred and sixty-five-day returns using Quince.com/hhtr. Like what you're hearing?WANT MORE SOUND IDEAS FOR DEEPER THINKING? Check out More Mental Fitness by Harvesting Happiness bonus content available exclusively on Substack and Medium.
To effectively unwind from the demands of modern life, we can tap into our body's internal chemistry. Overcoming the fatigue induced by constant technological stimulation is achievable by recognizing our need for rebalancing and actively changing our habits. The solution lies in getting a daily dose of nature, whole foods, physical exercise, and minimizing screen time.To introduce practices that activate and boost our natural stress defence, Harvesting Happiness Podcast Host Lisa Cypers Kamen speaks with neuroscientist, best-selling author, and founder of The DOSE Lab, TJ Power.TJ empowers us with brain boosting tips from his book, The DOSE Effect: Optimize Your Brain and Body by Boosting Your Dopamine, Oxytocin, Serotonin, and Endorphins.This episode is proudly sponsored by:Buffy Bedding — Offers a new standard of rest and nightly self-care ritual. Visit buffy.co to get 20% off your first order using promo code HHTR.Quince—Offers high-quality essentials, home decor, and furnishings at radically low prices.Visit Quince.com/hhtr for free shipping on your order and three hundred and sixty-five-day returns using Quince.com/hhtr. Like what you're hearing?WANT MORE SOUND IDEAS FOR DEEPER THINKING? Check out More Mental Fitness by Harvesting Happiness bonus content available exclusively on Substack and Medium.
What causes depression? Surprisingly, depression has nothing to do with your brain and everything to do with your gut microbiome. In this video, we'll take an in-depth look at the brain-gut connection and the often overlooked relationship between depression and gut health. 0:00 Introduction: Depression explained1:17 Side effects of SSRIs1:32 St. John's wort and depression2:27 The brain-gut connection3:22 Depression and gut health3:40 Depression and gut inflammation 3:51 Antibiotics and depression4:33 L. reuteri and mental healthDepression has consistently been viewed as a chemical imbalance, but it's actually related to a problem with the gut. Depression is often treated with SSRIs (selective serotonin reuptake inhibitors), but many studies show normal serotonin levels in people with depression.SSRIs do not fix depression and have even been called placebos by some medical professionals. They also come with serious side effects, including sexual dysfunction, decreased libido, inability to experience emotion, and worsening depression.St. John's wort affects both serotonin and dopamine. It's an anti-inflammatory and reduces cortisol, but doctors and the medical world often recommend against it despite its very few side effects. Serotonin and oxytocin are made in the gut. Oxytocin is a powerful hormone that can help with depression and stress, so gut health is at the core of mental health. The vagus nerve works as a highway that orchestrates the brain and gut connection. If you have a problem with your gut microbes, this can lead to depression. Studies have found serious microbes missing in depressed people! Gut inflammation can also alter your mood. One of the side effects of antibiotics is depression. Antibiotics erase the good bacteria that control your mood chemicals. Once wiped away, microbes don't always come back, and you could be left with an imbalance. L. reuteri is an amazing microbe that many people are missing. Dr. William Davis has shared an expert technique for cultivating L. reuteri using half and half to increase its potency. People have consumed this probiotic mixture and experienced significant health benefits such as improved sleep, muscle tone, and reduced stress. L. reuteri acts as a natural antibiotic without side effects and is found naturally in breast milk.
Du schläfst genug – und fühlst dich morgens trotzdem müde?Wachst du nachts immer wieder auf, ohne zu wissen warum? Dann ist dein Darm vielleicht der versteckte Übeltäter!In dieser Folge erfährst du:Warum ein gestörter Darm deinen Schlafrhythmus massiv beeinflussen kannWelche Rolle Histamin, Blutzucker & stille Entzündungen spielenWarum Melatonin & Serotonin im Darm entstehen – und was das mit deinem Schlaf zu tun hatWas deine Ernährung mit Durchschlafproblemen zu tun hatWie du deinen Darm und dein Nervensystem in Balance bringst – für besseren Schlaf———————————————————Im Podcast erwähnt:Darmcode ProgrammNährstoff WorkshopMagnesium von Next VitalFemblends Website: www.femblends.deFemblends Instagram: @fem.blendsDarm Balance TestDarm Balance Workshop——————————————————Du möchtest keine Folge verpassen und zusätzliche Tipps direkt in Dein E-Mail Postfach bekommen? Dann melde Dich für meinen Newsletter an und erhalte meine 11 darmfreundlichen Rezepte, die auch Meal Prep geeignet sind.Newsletter & FreebieDeine Gedanken zu meinem Podcastfolge kannst Du mir gerne auf Instagram unter dem Post mitteilen oder auch per Mail zusenden: info@hannah-willemsen.com.Du würdest mir einen riesen Gefallen tun, wenn Du meinen Podcast auf iTunes mit 5 Sternen bewertest. So finden andere diesen Podcast auch und erhalten ebenfalls wertvolle Tipps zum Thema gesunde Ernährung.Alles LiebeDeine Hannah
What if I told you that self-love isn't just a mindset - but a chemical response happening inside your body, right now? Dopamine. Oxytocin. Serotonin. Endorphins. These aren't just fancy science words - they're the feel-good ‘dream team' - the chemicals that light you up from the inside out. The chemicals we want our body producing to support us in feeling all loved up. Problem is… Most of us wait for something outside of us to trigger the release of these chemicals; a compliment, a hug, a win… But what if I told you that you can create these chemicals on demand? What if you could hack your brain to feel more love, more joy and more connection - without waiting for life to hand it to you? Today on I Love Me The Podcast, we're diving into the science of self-love. You'll learn how these powerful chemicals work, why they matter, and - most importantly - how to activate them naturally to feel amazing anytime, anywhere. So if you're ready to mix up your own self-love cocktail, then let's go. Take a peek at the full episode show notes (and resources I refer to in the show) here: https://gettingnaked.com.au/2025/05/07/the-self-love-chemical-cocktail-the-science-behind-feeling-good/ About me… My name is Tamra Mercieca and I've been studying and teaching self-love worldwide for 20+ years now. In 2011 I launched my online school Getting Naked where I offer programs to help people strip off the stories and childhood conditioning, so they can fall in love with themselves. While I go by many labels - mumma, wife, tea lover, drummer - professionally I'm known as a Self-Love Therapist, Writer and Women's Pelvic Health Guide, qualified in over a dozen physical and mental health modalities. I'm the author of two books, have been published in dozens of print and online publications, appeared on TV many times, and love to share the teachings of self-love at yoga and spirituality festivals. Personally, my journey began when I worked out how to overcome suicidal depression and anxiety (and get off my meds). I then went on to create a ten-session program where I now help others do the same. If you'd like to read my full love story and bio - including all my credentials - head to https://gettingnaked.com.au/tamra/ Resources… Ep.45 Self-massage. The healing power of loving touch. https://gettingnaked.com.au/2025/02/26/ep45-self-massage-the-healing-power-of-loving-touch/ Ep.41 Chasing care around your head? Let's meditate. https://gettingnaked.com.au/2024/12/11/ep-41-chasing-cars-around-your-head-lets-meditate/ Ep.32 Bye bye blues. My journey out of depression… https://gettingnaked.com.au/2024/10/09/ep-32-bye-bye-blues-my-journey-out-of-depression/ Ep.29 Could practising gratitude make you a happier person? https://gettingnaked.com.au/2024/09/18/ep-29-could-practising-gratitude-make-you-a-happier-person/ Ep.49 Balance your mind and body with this simple breath practice. https://gettingnaked.com.au/2025/03/26/ep-49-balance-your-mind-and-body-with-this-simple-breath-practice/ Ep.33 Could laughter be the medicine you need right now? https://gettingnaked.com.au/2024/10/16/could-laughter-be-the-medicine-you-need-right-now/ Just One Tree https://www.justonetree.life/ A percentage of profits from all programs sold go to the not-for-profit organisation Just One Tree, so they can plant trees on our behalf. Contact… Website: https://gettingnaked.com.au/ Instagram: https://www.instagram.com/gettingnaked/ Facebook: https://www.facebook.com/RelationshipQueen/ Music written by Tamra Mercieca and Grey Milton. Performed by Xani Kolac and Grey Milton.
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Welcome to this Mad in America podcast. My name is Robert Whitaker, and I'm happy today to have the pleasure of speaking with Joanna Moncrieff. Dr. Moncrieff is a psychiatrist who works in the National Health Service in the United Kingdom. She is a Professor of Critical and Social Psychiatry at University College, London. In 1990 she co-founded the Critical Psychiatry Network, which today has about 400 psychiatrist members, about two-thirds of whom are in the United Kingdom. From my perspective, the Critical Psychiatry Network has been at the forefront of making a broad critique of the disease model of care. Without this network, I don't think that critique would be anywhere near as prominent or as sophisticated as it is today. Dr. Moncrieff is a prolific researcher and writer. Her books include De-Medicalizing Misery, The Bitterest Pills: The Troubling Story of Antipsychotic Drugs, and The Myth of the Chemical Cure. Her latest book is titled Chemically Imbalanced: The Making and Unmaking of the Serotonin Myth. This book in many ways is a follow-up to her 2022 paper which looked at the serotonin story and concluded that there was no good evidence that a serotonergic deficiency was a primary cause of depression. It caused quite a furor within the media and in psychiatry. *** A full transcript of this interview is availabe here: https://www.madinamerica.com/2025/04/chemically-imbalanced-joanna-moncrieff-making-unmaking-serotonin-myth/ Thank you for being with us to listen to the podcast and read our articles this year. MIA is funded entirely by reader donations. If you value MIA, please help us continue to survive and grow. https://www.madinamerica.com/donate/ To find the Mad in America podcast on your preferred podcast player, click here: https://pod.link/1212789850 © Mad in America 2025. Produced by James Moore https://www.jmaudio.org
“ If you can fix your relationship with your phone and food, big shifts happen with your mental health,” explains Tj Power. Power, lead neuroscientist, author, and founder of the DOSE Lab, joins us today to explore the vital role neurotransmitters play in our health, how to naturally boost dopamine, and how to build routines that set you up for long-term success. Plus: - Neurotransmitters 101(~2:25) - Dopamine levels (~3:20) - How to naturally support dopamine levels (~4:00) - Boredom & the impact on the brain (~5:30) - Health implications for low dopamine (~6:55) - Routines to set yourself up for success (~7:55) - Dopamine & technology (~10:55) - What is oxytocin (~15:15) - How to increase oxytocin (~16:20) - Serotonin & the gut (~22:18) - Endorphines & destressing (~26:10) - Exercise as an elixir (~28:55) - The importance of play (~32:00) - Time alone (~33:45) - Reward systems & dopamine (~36:00) - The importance of sleep (~43:00) Referenced in the episode: - Follow Tj on Instagram (@tjpower) - Learn more about his research (https://thedoselab.com/lab) - Pick up his book, The Dose Effect - What Made Maddy Run by Kate Fagan - Research on texting vs calling on hormones (PMCID: PMC3277914) We hope you enjoy this episode, and feel free to watch the full video on YouTube! Whether it's an article or podcast, we want to know what we can do to help here at mindbodygreen. Let us know at: podcast@mindbodygreen.com. Learn more about your ad choices. Visit megaphone.fm/adchoices
In this episode, we explore the critical role of serotonin in shaping sensory maps within the brain, a process vital for interpreting sensory input and navigating the world. Serotonin, a neurotransmitter and neuromodulator synthesized from the aromatic amino acid tryptophan, influences brain development by fine-tuning sensory systems. It modulates neuronal growth, synaptic connections, and plasticity, which are essential for creating accurate sensory maps in regions like the somatosensory cortex, visual cortex, and auditory cortex. These maps serve as blueprints for processing touch, vision, and sound, with serotonin regulating the pruning of connections in the thalamus and cortex to ensure precise sensory wiring.The episode also explores the broader biological implications of serotonin, emphasizing its role in both prenatal and postnatal development. Maternally derived serotonin, supplied via the placenta from the peripheral and enteric nervous systems, significantly influences fetal brain development, affecting proliferation, differentiation, and neuronal migration in sensory regions. Postnatally, serotonin continues to support sensory integration and mood regulation, working alongside oxytocin to facilitate bonding and stress buffering. We explore environmental factors, such as stress and modern lighting, on serotonin synthesis and the hypothalamic-pituitary-adrenal (HPA) axis, which regulates cortisol release. Daylight Computer Companyuse "autism" for $25 off athttps://buy.daylightcomputer.com/RYAN03139Chroma Iight Devicesuse "autism" for 10% discount athttps://getchroma.co/?ref=autism0:00 Chroma Light Devices, use "autism" for a 10% discount03:12, Sensory Map Introduction and Serotonin's Role, The episode introduces sensory maps, neural blueprints that help the brain interpret sensory inputs like touch, vision, and sound, 04:30, Serotonin's Developmental Impact, Serotonin fine-tunes sensory systems by modulating neuronal growth, synaptic connections, and plasticity, creating precise sensory maps in the somatosensory, visual, and auditory cortices,06:04, Serotonin and Sensory Processing (Visual), Serotonin, sensory processing in the visual cortex08:29, Critical Periods and Neuroplasticity, sensory neurons and connections, pruning10:00, Brain Regions and Serotonin's Mechanisms, Serotonin, axonal guidance, neurogenesis, and migration via microtubules, brain-derived neurotrophic factor (BDNF), glutamate and GABA12:55, Serotonin and Sensory Processing (Somatosensory),13:51, Serotonin and Sensory Processing (Auditory),14:52, Stress and the HPA Axis, Cortisol, circadian rhythms and cortisol spikes, modern environments,16:16 Daylight Computer Company, use "autism" for a $25 discount20:38, Maternal Serotonin and Prenatal Influence; Postnatal Serotonin and Oxytocin; Tryptophan Metabolism and Neurodevelopment, placenta, fetal brain development, proliferation, differentiation, and neuronal migration, serotonin, oxytocin & bonding and stress buffering, TPH1 and TPH2, kynurenine pathwayX: https://x.com/rps47586Hopp: https://www.hopp.bio/fromthespectrumYT: https://www.youtube.com/channel/UCGxEzLKXkjppo3nqmpXpzuAemail: info.fromthespectrum@gmail.com
Are you tired all the time? Energy is crucial to everything we do, from getting out of bed in the morning to getting work done throughout the day, and unfortunately it isn't as simple as just getting enough sleep. In this mini-episode, I'm giving you science-backed hacks you can use today to feel better tomorrow. As always, I don't recommend tackling all of these changes at once – instead, pick and choose a few changes that feel helpful to you, and build up from there. You deserve to feel present and reclaim your energy! 1:29 Meal Timing 3:36 Circadian Rhythm 6:27 Stress 9:14 Suppressing Emotions 13:14 Hydration 14:24 Movement 16:30 Busy, Not Productive 21:22 Task-Switching 23:51 Nagging To-Dos Ready to uplevel every part of your life? Order Liz's book 100 Ways to Change Your Life: The Science of Leveling Up Health, Happiness, Relationships & Success now! To join The Liz Moody Podcast Club Facebook group, go to www.facebook.com/groups/thelizmoodypodcast. Connect with Liz on Instagram @lizmoody or online at www.lizmoody.com. Subscribe to the substack by visiting https://lizmoody.substack.com/welcome. Check out these previous episodes of The Liz Moody Podcast mentioned in this episode: How To Work LESS AND Get MORE Done Top Attention Researcher: Our Attention Spans Are Down To 47 Seconds! Here's How To Fix It Neuroscience Hacks For Optimizing Dopamine, Serotonin, Oxytocin, BDNF, And More The Secret to Getting in Shape, Sleeping Better, Saving Money, And Being More Confident and Productive (Yes, Really!) with Dr. Katy Milkman New Circadian Science: Improve Your Energy, Metabolism, Focus, Strength, & More This episode is sponsored by: LMNT: go to DrinkLMNT.com/LizMoody to get a free LMNT sample pack with any order. Listen to Pulling The Thread with Elise Loehnen wherever you listen to podcasts, and check Elise out on Instagram @eliseloehnen. The Liz Moody Podcast cover art by Zack. The Liz Moody Podcast music by Alex Ruimy. Formerly the Healthier Together Podcast. This podcast and website represents the opinions of Liz Moody and her guests to the show. The content here should not be taken as medical advice. The content here is for information purposes only, and because each person is so unique, please consult your healthcare professional for any medical questions. The Liz Moody Podcast Episode 320. Learn more about your ad choices. Visit megaphone.fm/adchoices
Join the Bodybuilding-friendly HRT Clinic - Get professional medical guidance on your health as a bodybuilder:[ Pharma Test, IGF1, Tesamorelin, Glutathione, BPC, Semaglutide, Var troche, etc]https://transcendcompany.com/patient-intake-form/?ls=Nyle+NaygaWatch it: https://www.youtube.com/watch?v=6Ihq4tIzyS8&t=5618sRP Hypertrophy Training App: rpstrength.com/nylePlease share this episode if you liked it. To support the podcast, the best cost-free way is to subscribe and please rate the podcast 5* wherever you find your podcasts. Thanks for watching.To be part of any Q&A, follow trensparentpodcast or nylenayga on instagram and watch for Q&A prompts on the story https://www.instagram.com/trensparentpodcast/Huge Supplements (Protein, Pre, Defend Cycle Support, Utilize GDA, Vital, Astragalus, Citrus Bergamot): https://www.hugesupplements.com/discount/NYLESupport code 'NYLE' 10% off - proceeds go towards upgrading content productionYoungLA Clothes: https://www.youngla.com/discount/nyleCode ‘NYLE' to support the podcastLet's chat about the Podcast:Instagram: https://www.instagram.com/trensparentpodcast/TikTok: https://www.tiktok.com/@transparentpodcastPersonalized Bodybuilding Program: https://www.nylenaygafitness.comTimestamps:00:00 Intro02:00 Genetics & Steroid Response06:10 Building a Family While Competing09:45 Health After Bodybuilding13:00 The Reality of TRT After Pro Life17:00 Testosterone and Brain Chemistry21:00 How to Survive the Health Phase25:00 Bloodwork Isn't Everything30:00 Estrogen: More Than a Number35:00 Glutathione & Antioxidants40:00 Liposomal Supplements Are OP44:00 Genetic Testing for Bodybuilders49:00 Personalized Medicine is the Future54:00 Fast vs Slow Steroid Metabolizers58:00 Drug Dosage ≠ Death Risk01:02:00 The Oral Steroid Blind Spot01:04:30 When Should You Start PEDs?01:10:00 A Warning for the Younger Guys01:13:00 What's the Right Age to Begin?01:16:00 Final Thoughts01:32:23 Sleep Troubles & Insomnia Hacks01:35:00 Biochemistry of Falling Asleep01:38:00 Dopamine, Serotonin & Brain Dumping
Ich bin ein wenig verliebt in meine neusten Erkenntnisse zum Thema Gehirnchemie und Glück. Es ist so ein leichter, klarer Weg, um zu verstehen was guttut und was nicht. Manche unserer Angewohnheiten sind wider der Natur, mit der unser Körper, einschließlich seiner Schaltzentrale in unserem Kopf, funktioniert. Doch es gibt einen Ausweg, denn Angewohnheiten lassen sich ändern und der Effekt, den ich gerade fühle, ist phänomenal. Also geht es in dieser Folge weiter mit Dopamin, Oxytocin, Serotonin und vielem mehr. Ich bin gespannt auf deine Gedanken zur Folge. Was willst du ändern oder ist alles schon wunderbar? Lass gerne einen Kommentar auf www.gluecksplanet.com da und tagg mich auf Instagram oder schreib einen Kommentar auf Youtube, wenn dir die Folge gefallen hat – ich freue mich von dir zu hören. Diese Folge ist noch einmal (wie schon Folge 316) inspiriert von der Arbeit von TJ Power, einem Neurowissenschaftler, der in seinem Buch „The Dose Effect“ über die Chemie in unserem Gehirn und wie wir sie für uns nutzen können, schreibt. (Link führt zum Ecobookstore, non affiliate. Diese Radikal Glücklich Folge #238: Versteh den Algorithmus deines Kopfes kann auch spannend sein, wenn dich das Thema interessiert.In uns können wir alles ändern. Von Herzen,SiljaPS: Mehr von mir findest du auf meiner Seite:www.siljamahlow.deUnter Coaching meine Coachingprogramme und einen Link zu den von mir ausgebildeten Soul Coaches. Wenn du mehr zu ätherischen Ölen und Supplements erfahren willst oder mit mir dein Doterra - Business aufbauen willst – ich bin gerne an deiner Seite. Schreib mir einfach eine E-Mail an silja@siljamahlow.deMein zweites Buch Spiritual Leadership findest du überall. Hier ist der Link zum Buch. Mein erstes Buch findest du hier.Mentioned in this episode:Diese Folge enthält Werbung für meinen neuen Podcast „Zurück zur Natur“, in dem ich über ätherische Öle spreche und wie sie dir Rückenwind geben können. Du findest ihn überall, wo es Podcasts gibt und mit Player auf meiner Welt der Öle Plattform.
Welcome back to another episode. Today, I’m sharing something a little different – a book review! And oh my goodness, this one is so worth your time. The book is called The Dose Effect by Dr. TJ Power – and it’s one of the most relevant, practical, and powerful books I’ve read in a long time. It was actually recommended by Anna from our GROW Book Club (thank you, Anna!), and it honestly feels like one of those rare books that lands in your hands just when you need it. In this episode, I walk you through the key idea of the book – how our feelings, motivation, energy and even our sense of joy are directly influenced by four brain chemicals: Dopamine, Oxytocin, Serotonin and Endorphins. Together they spell D.O.S.E. — and understanding them might just be the missing piece if you’ve been feeling flat, anxious, or off balance lately. Here’s what you’ll take away from listening: ✨ What “The Dose Effect” is and why it’s such a game-changer ✨ How modern habits are hijacking our brain chemistry without us realising ✨ Simple, science-backed ways to restore your natural balance It’s not about being perfect – it’s about small shifts that help us feel more like ourselves again. I’ll also share how you can read along with me and the Dream Life community inside our GROW Book Club this May! So if you’re ready for a reset, or just want to understand your beautiful brain a bit better — tune in. This could be a turning point
In this episode, we explore Oxytocin and Vasopressin's vast roles in Human Biology. We time travel to cover the evolution of the two molecules and learn about their functions with developing and socializing. Oxytocin and Vasopressin are dynamic molecules whereby they are Peptides and Hormones. In addition, we cover previously discussed brain regions and how the molecules work alongside key Neuromodulators like Serotonin and Dopamine.Social Reward https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6214365/Social Reward Requires Oxytocin and Serotonin in Nucleus Accumbens (Parvo Path) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4091761/Magnocellular and Parvocellular social Information Processing https://www.cell.com/neuron/fulltext/S0896-6273(20)30770-4?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0896627320307704%3Fshowall%3DtrueMagnocellular and Parvocellular https://onlinelibrary.wiley.com/doi/10.1111/jne.12284Meta-Analysis of Intranasal https://pubmed.ncbi.nlm.nih.gov/?term=intranasal+oxytocin+autism&sort=pubdate&filter=pubt.meta-analysishttps://pubmed.ncbi.nlm.nih.gov/33400920/Intranasal Review https://pubmed.ncbi.nlm.nih.gov/38579916/(0:00) Intro; Oxytocin and Vasopressin; Episode Objectives(2:46) Oxytocin and Vasopressin; 700 million year time travel (Phylogeny)(4:12) Peptides and Hormones; Modes of Transmission- Endocrine, Paracrine, Synaptic(6:35) Proteins and Peptides; Amino Acids and Aromatic Amino Acids and Light(8:58) Magnocellular and Parvocellular(12:33) Roles of Oxytocin and Vasopressin and connections to various Brain Regions(22:20) Scientific Literatures(27:12) Oxytocin and Serotonin; 1) Reward Processing, 2) Fear Response, 3) Social-Emotional Processing(30:07) Oxytocin and Dopamine(31:08) Dopamine Receptors(31:37) GABA(33:57) Intranasal Oxytocin(36:08) Take aways from Intranasal Literature(37:24) Biggest Take Away (Magnocellular versus Parvocellular and Intranasal Administration)email: info.fromthespectrum@gmail.com
Text Dr. Lenz any feedback or questions In this episode of the Conquering Your Fibromyalgia podcast, Dr. Michael Lenz delves into the complex relationship between hormones and chronic pain conditions such as fibromyalgia, migraines, dysmenorrhea, and others. The focus is on Premenstrual Dysphoric Disorder (PMDD), exploring the impact of estrogen and progesterone fluctuations on pain perception and symptom management. Key studies are discussed to highlight the relationship between menstrual cycles and fibromyalgia symptoms. The episode also covers the genetic, neurobiological, and environmental factors contributing to PMDD, as well as treatment options ranging from SSRIs and hormonal treatments to lifestyle changes and cognitive behavioral therapy. The intricate link between ADHD in women and mood disorders like PMDD and depression is also examined.00:00 Introduction to Hormones and Chronic Pain00:56 Understanding Hormonal Fluctuations02:26 Clinical Studies on Hormones and Pain03:48 The Role of Estrogen and Progesterone04:42 Historical Perspective on Premenstrual Disorders06:28 Diagnosing PMDD: Symptoms and Criteria07:39 Causes and Brain Sensitivity in PMDD09:35 Genetic and Neurobiological Factors10:45 Serotonin and Allopregnanolone in PMDD12:06 Stress, Inflammation, and PMDD13:33 Treatment Options: SSRIs and Hormonal Therapies16:26 Advanced Treatments and Surgical Options21:06 ADHD and Hormone-Related Mood Disorders27:43 Managing PMDD: Lifestyle and Non-Pharmacological Approaches31:12 Conclusion and Final Thoughts Click here for the Fibromyalgia 101 link.Click here to connect with Joy Lenz. Support the showA Fibromyalgia Starter Pack, a great companion to the book Conquering Your Fibromyalgia, is now available. Dr. Michael Lenz practices general pediatrics and internal medicine primary care, seeing patients from infants through adults. In addition, he also will see patients with fibromyalgia and related problems and patients interested in lifestyle medicine and clinical lipidology. To learn more, go to ConquringYourFibromyalgia.com. Remember that while Dr. Lenz is a medical doctor, he is not your doctor. All of your signs and symptoms should be discussed with your physician. He aims to weave the best of conventional medicine with lifestyle medicine to help people with chronic health conditions live their best lives possible. Dr. Lenz hopes that the podcast, book, blog, and website serve as a trusted resource and starting point on your journey of learning to live better with fibromyalgia and related illnesses. Junior Producer- Brooklyn Lenz
Nutritionist Leyla Muedin explores the connection between positive thinking and physical health. She discusses how a positive mindset can improve heart health, immunity, and energy levels, while reducing stress and fatigue. Leyla also shares practical habits to boost positivity and overall well-being, emphasizing the holistic approach to mental and physical health. The episode is backed by scientific research and provides actionable tips for enhancing daily life through optimism.
There's a quiet powerhouse living in your belly—and it's shaping your mood, your clarity, and your capacity to live fully. I'm talking about your gut, often called your “second brain.” Why? Because nearly 95% of your serotonin, your “feel-good” neurotransmitter, is produced there—not in your head. Serotonin influences your mood, your sleep, your appetite, even how you feel about your life. And the gut? It's the soil where that neurochemical magic begins. Let's break it down: When you nourish your gut with whole, clean, fiber-rich foods… When you move your body and hydrate with intention… When you create space for calm, connection, and conscious breathing… You're not just supporting digestion—you're building the biochemical foundation for joy, confidence, and clarity. We are not separate systems—we are one beautifully integrated ecosystem of mind, body, and spirit. When we love and care for the gut, we ignite our innate capacity for elevated living. This is the art of every day. Love your gut. Elevate your serotonin. Rise in your light. #GutHealth #SerotoninSupport #LoveAndLifeElevated #TheArtOfEveryDay #sunlight #serotonin #melatonin
Send us a textIn this episode, we explore the neurotransmitters that make up the acronym DOSE - Dopamine, Oxytocin, Serotonin, and Epinephrine - and how they affect our daily lives and well-being.Episode Highlights:Dopamine: The Pleasure & Reward NeurotransmitterEvolved to reinforce behaviors that help us survive as individuals and as a speciesModern hijacking through engineered experiences (processed foods, social media, alcohol)The importance of finding healthier sources of dopamine throughout your dayOxytocin: The Connection HormoneCreates bonds between humans that enable our species to thriveMany physicians are likely running low on this "love hormone"Simple ways to increase oxytocin through meaningful connectionSerotonin: The Mood & Wellbeing NeurotransmitterThe mind-gut connection and how our diet affects serotonin productionWhy physicians often end up on SSRIs and whether better self-care could reduce this needImportance of prioritizing sleep, sunlight, exercise, and proper nutritionEpinephrine/Endorphins: The Energy & Excitement ChemicalNot just about fight-or-flight responses but also positive excitementHow many of us over-rely on caffeine for our energy needsBetter sources: exercise, healthy intimacy, adventure, and novel experiencesKey Takeaways:Where do YOU need to adjust your DOSE?Where are you currently getting these neurotransmitters in your life?Are these sources aligned with your health and life goals?What small, intentional changes can you make to create a more balanced neurochemical experience?Resources Mentioned:Email me at megan@healthierforgood.comNote: This episode discusses food and alcohol consumption, which may be triggering for some listeners with histories of disordered eating or addiction.Connect with us:Website: healthierforgood.comEmail: megan@healthierforgood.comInstagram: @meganmelomdIf you enjoyed this episode, please leave a review and share with a colleague who might benefit! Support the showTo learn more about my coaching practice and group offerings, head over to www.healthierforgood.com. I help Physicians and Allied Health Professional women to let go of toxic perfectionist and people-pleasing habits that leave them frustrated and exhausted. If you are ready to learn skills that help you set boundaries and prioritize yourself, without becoming a cynical a-hole, come work with me.Want to contact me directly?Email: megan@healthierforgood.comFollow me on Instagram!@MeganMeloMD
Discover more Sincerely Accra!Descriptor From Naija to New York, jump into the world of Sofiyat Ibrahim aka "The Odditty". One of the most influential voices in the influencer space and how she built her brand brick by brick to attain the heights she has achieved at such a young age. Press Play! Opening Theme Music Oshe - Reynolds the Gentleman ft Fra!Music BridgesGood Girl - DJ Vyrusky ft Joey B X Shaker Venus (Bass Version) - Faceless, Serotonin & King Of Grooves Gree 4 U - Niashun ft. Darkua Steeze & Composure - Dope Nation Sweet Love - Blaq Pages ft Bapi Joss Music Closer Radar - Efya A GCR Production - Africa's Premiere Podcast Network
“Our gut is referred to as the second brain, for a reason; it plays a massive role in regulating our emotions and energy." - Sherry ShabanHave you ever wondered why stress, emotions, and even past experiences can impact your digestion and overall health? In this episode, I talk about how our gut and brain are closely connected. Our emotions and thoughts are tied to how our body feels and how it digests food. Understanding how stress and emotions affect our bodies can help us see why our metabolism and gut health play a big role in losing weight and feeling well.I also explain how hormones like dopamine, serotonin, and oxytocin make us feel happy and balanced and how they are influenced by both our mind and gut health. Instead of just focusing on food, I share how everything around us impacts our well-being.Throughout the episode, I offer simple tips to help you be kinder to yourself and build a better relationship with food. Whether you're struggling with weight or emotional eating, this conversation can help you find a healthier, happier path forward!‘Topics Covered:The Gut-Brain Connection and Its Impact on EmotionsThe Impact of Negative Self-Talk on Body and MindThe Body's Response to Stress and Sugar StorageUnderstanding the Gut-Brain Connection and Food ScarcityIdentifying and Overcoming Out-of-Control Eating BehaviorsUnderstanding Dopamine and Serotonin in the Brain's Reward SystemThe Pursuit of Oxytocin and the Role of DopamineEmbracing Transformation Through Support and Self-ReflectionMastering Stress Response Through Re-Education and Re-SensitizationExploring Food Sensitivities and Personalized Nutrition ApproachesIf you've ever felt like food has power over you, I hope this conversation brings you comfort and inspiration. You're not alone, and healing is possible.If you've ever felt like you're doing everything right—eating well, exercising, pushing yourself—but your body just won't let go of fat, there's a reason.Your nervous system is either in Protection Mode (fight-or-flight) or Safety Mode (rest-and-digest)—and fat release only happens in Safety Mode. But if your body feels unsafe? It clings to fat, slows metabolism, and even triggers binge eating and self-sabotage.Think about it. You go through stress, and suddenly you're reaching for food you swore you wouldn't touch. You're not weak—it's biology. When your body is in survival mode, it's wired to conserve energy and seek quick fuel. That's why unwanted eating behaviors feel so out of control sometimes.But here's the kicker: fat loss isn't just about burning calories—it's about making your body feel safe enough to let go.So the real question is—are you pushing your body into Protection Mode without even realizing it? Because if you are, no amount of dieting or exercise is going to override survival mode.It's time to stop fighting your body and start working with it.Join my 3-Day Stop The Cycle Masterclass on April 7-9, 2025.Register Here: https://www.sherryshaban.com/stopthecycleYou deserve to experience food freedom, I can't wait to see you inside!Download FREE E-Book: https://www.sherryshaban.com/calm-the-cravingsBook a Food Freedom Strategy Call with me www.calendly.com/sherryshaban/makepeacewithfoodJoin my Facebook CommunitySubscribe to the podcast so you never miss an episode! Spotify, iTunes, YouTubeShare your biggest takeaway and tag me on social media @makepeacewithfoodWant to go deeper? Visit www.makepeacewithfood.com to learn more!Join me for the Transformation in Paradise Empyrean Retreat in Costa Rica May 24-31, 2025. This will be the most transformative week of your life at the breathtaking Osa Peninsula in Costa Rica. Intrigued? Curious? Let's book a call to find out if this retreat is right for you. Just head on over to www.sherryshaban.com/retreats
You're doing it all but could there be hidden mistakes hijacking your menopause fitness. Increasing protein, lifting weights, doing high intensity… How can you be this active but not working? Disclaimer: This could trigger you. The mistakes hijacking your menopause fitness you could be doing on purpose because you were told once this is what you SHOULD DO. This episode is for all women, and for you. So let's unpack these mistakes hijacking your menopause fitness. Before anything.. Measure. If you aren't measuring your body composition - skeletal muscle mass vs. body fat—you won't truly know what's working. I'll link to the 4 Smart scales in my store. You can get a Dexa or go to a gym. #1 Not Consuming Enough Fuel Women are not the same as men on carbohydrate needs. We get little, we disrupt hormones. You are influenced by cortisol, insulin, thyroid, testosterone, growth hormone and the endocrine. How much fuel do you need? Endocrine dysfunction - ~30-35 calories per kg of FFM in women; but around 15 calories per kg FFM in men. Fat Free Mass (FFM) - say you're 130kg and you have 25% body fat. You need 2923 kcals to keep your body functioning well. Fueling Your Workouts: Cardio: 30g carbs and 15g protein before Strength: 15g protein before + 30-45g protein after (higher in and after menopause) Thyroid & Carbohydrates Low carb diets (under 100g) - pivotal point for lower thyroid function. Serotonin - produced in the gut, declines with low carb diets. Low-carb diets - don't lead to better weight loss long-term, they cause water loss. What Happens When You're Under-Fueled?Low Energy Availability from brain (hypothalamus) to body… Hypothalamus signals HPA axis dysfunction Adrenals releases cortisol Thyroid slows metabolism Body conserves energy and breaks down muscle instead of fat for fuel When You Fast, try one of these: High intensity intervals Lift heavy weights High intensity boot camp class Reduce carbs, maintain a keto-like diet while increasing your walks Know the Sneaky Mistakes Hijacking Your Menopause Fitness #2 Never REALLY Recovering From Hard Intervals or Hard Workouts Some bootcamps and spin classes are rapid, high-intensity intervals without adequate recovery. Your cortisol levels during this session accumulate. It feels like you crushed it, but here's the truth: if you're not giving yourself real recovery, you're not hitting your peak. When you skip the full recovery, you're not building the strength and power that protect against sarcopenia (muscle loss). Try these: Warm-up A: Run up a steep hill for 40 seconds Mark that point on the hill Slowly go back down Fully recover, with your nasal breathing. Repeat until you don't make it to the same spot on the hill Warm-up B: Run up a steep hill for 40 seconds Mark that point on the hill Quickly make your way down Cool down within 60 seconds Immediately run up again Repeat until you don't make it to the same spot on the hill They both will feel hard, but only one gets you to your maximum capacity. The glycolytic fibers - fast twitch that sustain power fatigue quickly. Women have fewer of them than slow twitch and lose twice as fast as slow-twitch fibers. Fast-twitch fibers need power moves — like heavy lifting or box jumps — and plenty of recovery to reload and go again. You're fooling yourself into thinking you're getting in better shape. So test yourself… a simple protocol you can do at home. Try a full test battery you can easily do at home - I'll provide access to it in the show notes as soon as it's ready. Measure. Monitor your waist girth, your body fat percent and your skeletal muscle. Rate your energy, sleep, focus, digestion and elimination. Are you improving, worse or the same? When you're exercising optimally these things also improve. It's not just muscle mass and fat. Are these Mistakes Hijacking Your Menopause Fitness? #3 Relying on Caffeine, Bar Codes and Over Emphasis on Packaged Food By nature, your cortisol level is highest at about 8am. You've fasted overnight and if you're not eating soon after waking, especially if you're exercising as a female, your body has stressor on top of stressor: Punched your ticket in midlife (less estrogen, more cortisol) Caffeine (more cortisol) No fuel (more cortisol) Exercise (more cortisol) Fuel before intense exercise. Fuel again after, especially within the 24 hour period after resistance training or other HARD workouts the need for recovery persists, so it's not just that single meal following activity. #4 Always High and Hard You have never needed high intensity more in your life than whatever age over 40 you are now. You also need full recovery … between intervals, strength training sets and sessions. Here's the secret: Muscle gets stronger between sessions. The exercise is the stimulus. The recovery is where fitness happens – the release of hormones, the repair and supercompensation. Recovery time. Get AT LEAST 48 to 72 hours between hard use of the same muscle groups. Active Recovery. The low intensity movement between your hard sessions is absolutely important in increasing circulation, blood sugar stabilization, improving sleep and mood and overall fitness levels. Keep It Simple: Movement Time. Walking at the level below where cortisol negatively spikes so you can reduce or optimize it. Short & Intense. Spend small amounts of time in high intensity interval session - where you recover completely between sessions. All Major Muscle Groups. Spend 2-3 sessions a week hitting all major muscle groups or twice to total muscle fatigue. If you're in post menopause, the volume of sets has to be greater compared to a perimenopause woman. Recover. Give yourself at least 48 hours.. 72 is often BEST. Resources: Flipping50 Membership Flipping50 Insiders Group Other Podcasts You Might Like: Previous Episode - Is Red Light Therapy the Answer to Aches, Pains and More Movement? Next Episode - 3 Short Strength Training Session Strategies for Women in Menopause More Like This - 12 Strength Training Mistakes in Menopause Robbing Your Results References: Loucks AB, Verdun M, Heath EM. Low energy availability, not stress of exercise, alters LH pulsatility in exercising women. J Appl Physiol (1985). 1998 Jan;84(1):37-46. doi: 10.1152/jappl.1998.84.1.37. PMID: 9451615. https://doi.org/10.1152/jappl.1998.84.1.37 Naude CE, Brand A, Schoonees A, Nguyen KA, Chaplin M, Volmink J. Low-carbohydrate versus balanced-carbohydrate diets for reducing weight and cardiovascular risk. Cochrane Database Syst Rev. 2022 Jan 28;1(1):CD013334. doi: 10.1002/14651858.CD013334.pub2. PMID: 35088407; PMCID: PMC8795871. https://doi.org/10.1002/14651858.cd013334.pub2 Shulhai AM, Rotondo R, Petraroli M, Patianna V, Predieri B, Iughetti L, Esposito S, Street ME. The Role of Nutrition on Thyroid Function. Nutrients. 2024 Jul 31;16(15):2496. doi: 10.3390/nu16152496. PMID: 39125376; PMCID: PMC11314468. https://doi.org/10.3390/nu16152496
In this episode, we review the high-yield topic of Selective Serotonin Reuptake Inhibitors (SSRIs) from the Psychiatry section.Follow Medbullets on social media:Facebook: www.facebook.com/medbulletsInstagram: www.instagram.com/medbulletsofficialTwitter: www.twitter.com/medbullets
In this episode, I sit down with Dr. Emilia Vuorisalmi, a medical doctor, researcher, and bestselling author known as Finland's Love Doctor. We dive deep into the science of love, heartbreak, and hormonal balance, exploring how dopamine, serotonin, and oxytocin shape our emotions, relationships, and overall wellbeing.Dr. Vuorisalmi shares her personal journey of overcoming love addiction, revealing how heartbreak can physically manifest in the body—and more importantly, how to heal. We discuss somatic therapy, breathwork, meditation, and lifestyle changes that help reset the nervous system and bring balance to our love hormones.Topics Covered:✔️ How love and heartbreak impact our brain chemistry✔️ The science behind love addiction and how to break free✔️ Dopamine, serotonin, and oxytocin - what they really do✔️ How to use breathwork and meditation to heal from emotional pain✔️ The hidden dangers of dating apps and dopamine addiction✔️ Why boundaries are key to healthy relationships✔️ The power of manifestation, self-worth, and connection
You think you're optimizing your brain—but what if the real culprit behind your brain fog, anxiety, and burnout is the modern world itself? In this episode, Columbia University psychiatrist and nutritional neuroscience pioneer Dr. Drew Ramsey joins Dave Asprey to decode the biological chaos hijacking your mind—and how to fight back. From inflammation and gut dysbiosis to screen-induced disconnection and hidden trauma, this is the ultimate roadmap for healing the modern brain. You'll explore the cutting-edge science of neuroplasticity, discover how movement and social connection trigger brain growth, and learn why food is still your most powerful antidepressant. Plus: dancing, psychedelics, kale debates, and why porn is quietly reshaping the male brain. What You'll Discover in This Episode: • Why brain fog, anxiety, and mood swings might be signs your brain is inflamed • How movement—especially dancing—can literally help your brain grow stronger • What your gut has to do with your mental health (and why some “healthy” foods can backfire) • The truth about antidepressants, supplements, and why there's no one-size-fits-all fix • Why porn, ultra-processed food, and doomscrolling are silently wrecking focus and drive • A new way to think about mental fitness—like a workout plan for your brain SPONSORS -BodyHealth | Go to https://bodyhealth.com/ and use code DAVE20 for 20% off your first order of PerfectAmino. -Zbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order. Resources: • A Day of Biohacking and Consciousness Event April 12th: https://daveasprey.com/biohacking-and-consciousness/ • Dave Asprey's New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ • Drew's Instagram: https://www.instagram.com/drewramseymd/?hl=en • Drew's Linktree: https://shorturl.at/CIIR5 • Danger Coffee: https://dangercoffee.com • Dave Asprey's Website: https://daveasprey.com • Dave Asprey's Linktree: https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com • Own an Upgrade Labs: https://ownanupgradelabs.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com Timestamps: • 00:00 – Trailer • 01:43 – Intro • 02:51 – The State of Mental Health Today • 04:00 – Nutritional Psychiatry and Personal Experiences • 05:21 – Environmental Factors and Brain Health • 05:55 – Chemical Balance and Psychiatry • 09:19 – Mental Fitness and Connection • 14:17 – Modern Brain Challenges • 16:26 – The Role of Movement and Dance • 22:44 – Sex, Relationships, and Mental Health • 34:02 – Microbiome and Mental Health • 36:50 – Transitioning to Urban Life and Mental Health • 37:29 – The Role of Nature in Mental Well-being • 38:14 – Personal Experiences with Gut Health • 39:45 – Trial and Error in Mental Health • 42:16 – Cognitive Resilience and High Performance • 45:37 – The Importance of Family Meals • 46:33 – Challenges of Rural and Urban Living • 47:53 – Brain Health: Beyond Neurons • 49:01 – Neuroplasticity and Mental Fitness • 52:50 – Biohacking Mental Health • 57:31 – The Role of Serotonin in Depression • 01:03:57 – Debating the Benefits of Kale • 01:12:03 – Final Thoughts on Mental Health and Resilience See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
"WHAT YOU THINK ABOUT, YOU BRING ABOUT. WHAT YOU BROUGHT ABOUT, YOU THOUGHT ABOUT." “Acts of kindness create a ripple effect of neurochemical uplift—benefiting the giver, receiver, and even the silent witness.” RECEIVING kindness can: Increase oxytocin, which helps regulate serotonin and dopamine. Reduce cortisol (the stress hormone), which helps rebalance neurotransmitters like serotonin. Lead to feelings of social connection, safety, and worth, which are correlated with serotonin boosts and immune function. GIVING kindness releases: Dopamine (pleasure/reward) Oxytocin (connection/love hormone) Serotonin (well-being, mood) These positive neurochemicals reduce inflammation and boost immune cell production. WITNESSING kindness can cause a release of oxytocin, leading to downstream effects on serotonin and immune function. The observer experiences what's called 'moral elevation'--which includes a sense of warmth and inspiration. This is associated with Heart rate variability improvements, cortisol reductions, and positive neurochemistry shifts (dopamine, serotonin).
Die Tage werden länger, die Natur erwacht – und trotzdem fühlst du dich müde und antriebslos? Dann könnte Tryptophan genau das Richtige für dich sein! In dieser Podcastfolge erfährst du: ✔️ Warum dein Körper im Frühling oft noch müde ist – und wie du ihn unterstützen kannst. ✔️ Was Tryptophan ist und warum es als Vorstufe von Serotonin deine Stimmung hebt. ✔️ Welche Lebensmittel reich an Tryptophan sind und wie du sie clever in deine Ernährung integrierst. ✔️ Was die Wissenschaft über Tryptophan und seine Wirkung auf Laune und Schlaf sagt. ✔️ Warum dein Darm eine entscheidende Rolle bei der Verwertung von Tryptophan spielt. Wenn du deinem Wohlbefinden also einen natürlichen Boost geben möchtest, dann hör rein! In diesem Sinne wünsche ich dir ganz viel Freude mit dieser Podcastfolge „Gute Laune im Frühling? Hol dir Tryptophan!“ Sei achtsam mit dir! Deine Nuria von Achtsam Schlank
Bob Colling Jr. & Dallas Gridley continues their journey with the hundred-and-forty-third episode of TNA iMPACT! from March 22, 2007 on Spike TV at the Impact Zone in Orlando, Florida. The Hell Froze Over Match is the main event as "The Monster" Abyss teams up with Sting for the first time to take on NWA World Heavyweight Champion Christian Cage & AJ Styles! Also, Kurt Angle, Rhino & Samoa Joe face off against Serotonin in a warm up match before Lockdown and Austin Starr goes one on one with Eric Young! Plus, NWA World Tag Team Champions LAX have a challenge for Team 3D, "Wildcat" Chris Harris demands to get his hands on James Storm, Jerry Lynn, Christopher Daniels, Gail Kim, Jackie Moore, Robert Roode and so much more! Join us for all this action in the iMPACT! zone once again! More TNA Cross The Line Podcast: tnacrosstheline.com Follow us on Twitter @CrossTheLineTNA Follow us on Facebook @TNACrossTheLinePod Follow us on Instagram @CrossTheLineTNA Subscribe to our YouTube Channel Shop at our Pro Wrestling Tees Store
On this episode of Raising Serotonin, I discuss the complexities of healing, the role of medication in personal growth, and the importance of self-love amidst self-doubt. I emphasize that setbacks are a natural part of the healing process and that one can still grow and learn while growing through what comes your way in life. FOLLOW RAISING SEROTONIN ON INSTAGRAM HERE SIGN UP FOR THE FREE RAISING SEROTONIN NEWSLETTER HERE
Episode Highlights With TinaHow health topics are now entering the mainstream conversation, and how this can be a net benefit for so many of us, separate from podcastsWe are each our own primary healthcare provider and CEO of our healthHigh-impact changes we can make in supporting our healthHow the gut and brain are connected and how this two-way communication can support both gut and brain health when we understand itMost of our serotonin and many other neurotransmitters are produced in our gut!For the immune system to work properly, we have to have good gut healthIf you have an autoimmune issue, you have leaky gut What digestive bitters are and how they support the gutHow these things were largely removed from the food supply in our modern diets Bitters can improve stomach acid and help with fat metabolism How probiotics and bitters do different thingsBitters specifically support the stomachWhy their bitters are in a capsule vs a liquid How to take and use bitters for maximal benefitResources MentionedJust Thrive - For a limited time, get 20% off your first bottle of digestive bitters and probiotics with promo code WM20
Are your daily habits killing your motivation? Neuroscientist TJ Power, once a self-confessed dopamine junkie reveals how phones and quick fixes tanked his focus and ambition. He broke free from phone and alcohol addiction with his D.O.S.E framework (Dopamine, Oxytocin, Serotonin, Endorphins) which has helped him reduce stress, boost sleep by 54%, and turned ambition into action with his 30-minute rule to reboot your brain and reclaim your drive. In this episode TJ provides you with science-backed hacks that help you ditch the morning scrolls, master flow state, and feel peace as an entrepreneur. Trust us when we say that TJ's raw story and practical tips will hook you instantly! _______________ Sign up to Wise Business banking: https://wise.com/uk/business/ Join Vanta and receive $1000 off: http://vanta.com/secretleaders Learn more about your ad choices. Visit megaphone.fm/adchoices
Bob Colling Jr. & Dallas Gridley continues their journey with the hundred-and-forty-second episode of TNA iMPACT! from March 15, 2007 on Spike TV at the Impact Zone in Orlando, Florida. NWA Tag Team Champions LAX team up with Alex Shelley to take on Team 3D in a 6-Man Tag Team Match in the main event! Plus, Jay Lethal is in action against Jerry Lynn and Kaz! Also, Jim Cornette sets the stage for Lockdown, Raven punishes Serotonin, AJ Styles has words for Rhino after his Elevation X loss and Sting & Abyss confront NWA World Heavyweight Champion Christian Cage & AJ Styles! Join us for all of this and so much more including out Destination X recap and all the news & rumors you love to hear about! More TNA Cross The Line Podcast: tnacrosstheline.com Follow us on Twitter @CrossTheLineTNA Follow us on Facebook @TNACrossTheLinePod Follow us on Instagram @CrossTheLineTNA Subscribe to our YouTube Channel Shop at our Pro Wrestling Tees Store
Is depression really caused by low serotonin? Dr. Awais Aftab joins Dr. David Puder to explore the serotonin hypothesis, antidepressant efficacy, and the controversies surrounding SSRIs. They dive into the history of the serotonin deficiency theory, key research on antidepressants vs. placebo, and how neuroplasticity, psychotherapy, and lifestyle changes factor into depression treatment. The episode also examines differences between major treatment guidelines, including RANZCP and NICE, and what the latest evidence suggests about the future of mental health care. By listening to this episode, you can earn 1.25 Psychiatry CME Credits. Link to blog. Link to YouTube video. Links for Dr. Awais Aftab: Substack World Psychiatry Conversations in Critical Psychiatry
Lesley Logan sits down with Sam Mandel, co-founder of Ketamine Clinics Los Angeles, to discuss the transformative potential of ketamine therapy for mental health. They debunk common misconceptions, explore its impact on PTSD, anxiety, and depression, and highlight how it empowers individuals to reshape their personal narratives.If you have any questions about this episode or want to get some of the resources we mentioned, head over to LesleyLogan.co/podcast. If you have any comments or questions about the Be It pod shoot us a message at beit@lesleylogan.co. And as always, if you're enjoying the show please share it with someone who you think would enjoy it as well. It is your continued support that will help us continue to help others. Thank you so much! Never miss another show by subscribing at LesleyLogan.co/subscribe.In this episode you will learn about:What ketamine therapy is and how it differs from traditional treatments.How ketamine enhances neuroplasticity and helps reframe traumaThe science behind ketamine's impact on depression, anxiety, and PTSD.The difference between medical ketamine use and recreational misuse.What to expect during a ketamine therapy session.How ketamine therapy can help individuals reconnect with themselves and regain motivation.Episode References/Links:Ketamine Clinics LA Website - https://Ketamineclinics.comInstagram - https://www.instagram.com/ketamineclinicslaFacebook - https://www.facebook.com/KetamineClinicsLASam Mandel Instagram - https://www.instagram.com/thesammandelGuest Bio:Co-founder & CEO of Ketamine Clinics Los Angeles (KCLA), Sam Mandel, is a tour-de-force of compassion and innovation in mental health care. From volunteering at a teen-to-teen suicide prevention hotline at twelve to pioneering one of the world's foremost Ketamine Infusion Therapy clinics in 2014 alongside his father, Dr. Steven L. Mandel, Sam has channeled his lifelong passion for healthcare advocacy into transforming lives for the better. Sam was featured in Entrepreneur's list of Top 10 Inspiring Healthcare Entrepreneurs to Watch in 2023 and acknowledged by MSN as an Entrepreneur Leading the Business Frontier in 2024. Numerous media outlets have interviewed Sam for his expertise in Ketamine Infusion Therapy, and he is a frequent speaker at medical conferences and events. Under his leadership, KCLA has provided over 30,000 infusions to over 6,000 patients with an 83% treatment success rate, establishing the field's gold standard treatment protocols and patient satisfaction. If you enjoyed this episode, make sure and give us a five star rating and leave us a review on iTunes, Podcast Addict, Podchaser or Castbox.DEALS! DEALS! DEALS! DEALS!Check out all our Preferred Vendors & Special Deals from Clair Sparrow, Sensate, Lyfefuel BeeKeeper's Naturals, Sauna Space, HigherDose, AG1 and ToeSoxBe in the know with all the workshops at OPCBe It Till You See It Podcast SurveyBe a part of Lesley's Pilates MentorshipFREE Ditching Busy Webinar Resources:Watch the Be It Till You See It podcast on YouTube!Lesley Logan websiteBe It Till You See It PodcastOnline Pilates Classes by Lesley LoganOnline Pilates Classes by Lesley Logan on YouTubeProfitable Pilates Follow Us on Social Media:InstagramThe Be It Till You See It Podcast YouTube channelFacebookLinkedInThe OPC YouTube Channel Episode Transcript:Sam Mandel 0:00 When you look at trauma, for example, ketamine is extremely helpful for depression and anxiety, but also for PTSD and a lot of people have some trauma that is at the root of one of those issues, and ketamine helps people to recraft the story around that trauma. Lesley Logan 0:16 Welcome to the Be It Till You See It podcast where we talk about taking messy action, knowing that perfect is boring. I'm Lesley Logan, Pilates instructor and fitness business coach. I've trained thousands of people around the world and the number one thing I see stopping people from achieving anything is self-doubt. My friends, action brings clarity and it's the antidote to fear. Each week, my guest will bring bold, executable, intrinsic and targeted steps that you can use to put yourself first and Be It Till You See It. It's a practice, not a perfect. Let's get started.Lesley Logan 0:59 Okay, Be It babe. This is going to be a different kind of episode, but in the best way. I have Sam Mandel, who is a founder of Ketamine Clinics in LA and I was really intrigued by what I know about ketamine from my friends' holistic doctors. And when he came up as someone I could interview, I was like, oh, we need to do this, because there is a lot of misinformation about ketamine and what ketamine can be used for, and I'm on a mission to help you be it till you see it. And I really want you to understand all the different ways that you can have support in feeling more like yourself and not letting things get in your way. And so that is why we're going to talk about ketamine today. And if you think you know what it is, I strongly encourage you to just stay and listen, because I thought I knew and I learned so much. And then on top of all of that, I really enjoy Sam's story of how he started these clinics and what he and his dad did. And so there's just a lot of beautiful information in this episode, and I can't wait for you to hear it. So here is Sam Mandel. Lesley Logan 2:00 All right, Be It babe. I am really excited. I can tell you for a fact, we've never talked about this on the Be It Pod. And only is it quite timely, I think it's actually extremely imperative that we have this discussion so we have Sam Mandel here on the show. We're gonna talk about ketamine and all things about it, ketamine therapy. Sam, can you tell everyone who you are and probably why you rock at ketamine therapy?Sam Mandel 2:25 Yes, yeah. Thank you so much for having me, Lesley. So, I am Sam Mandel. I'm the co-founder and CEO of Ketamine Clinics Los Angeles. We're one of the first ketamine clinics in the country, established in 2014 and we specialize in IV infusions of ketamine for mental health, but we also offer several other innovative therapeutics for mental health. Lesley Logan 2:45 I love that mental health is something more people are talking about, and there's like more awareness around it, but also that there can be clinics that are working on different ways of helping, supporting mental health, including these infusions. For people who have heard about ketamine, and maybe not the positive ways, can we kind of, can we just dive in and ease their nerves about what we're talking about here?Sam Mandel 3:07 Let's do it. Some of your listeners are definitely like, ketamine what? And there's five different people saying that it's five different things, and all of them are correct. So that's one of the interesting things about ketamine. It is, first and foremost, an FDA-approved anesthetic for humans. It was FDA-approved in 1970. This is an old medicine. It's also commonly used in veterinary medicine. So a lot of people know of it as a horse tranquilizer or a cat tranquilizer. In some circles, it's more commonly known as that than as a drug for humans. But there's a lot of medications that we use for humans, that we also use in veterinary medicine. And it's also a drug of abuse, or something that people use recreationally or self-medicate with, depending on how you want to look at it, known as Special K. Same drug. It's used as an analgesic, as a pain reliever, in emergency room departments and crisis situations, trauma situations, when someone's in a terrible accident, they're in pain, they need sedation, or someone goes in and they need their shoulder reset, they commonly will use ketamine for conscious sedation. So it is a ubiquitous drug. It has a lot of different uses and applications, and one of its most recent, or probably its most recent, addition to that list of its identities, if you will, is as a mental health treatment. And in the last 25 years, there's been a growing body of clinical research proving ketamine to really be among the fastest, if not the fastest-acting, safest, most effective depression treatments available today.Lesley Logan 4:36 I mean, it's kind of amazing that it can be all these different things, also not, right? Like there's so many things, I feel like there's a lot of untapped medicines out there that we're already using, and we don't realize it could be done for other things. Can we talk about how it helps? Because I'll say my family's understanding of mental health treatment is when you sit on a couch and you talk to a therapist and you go weekly if you're depressed, you can take a pill that will kind of help with some hormonal imbalances. But that's not what this is. Sam Mandel 5:01 Yes, that is not what this is. And by the way, talk therapy is great. I go to therapy every week, you know, even when I'm in a good place and I don't necessarily feel like I have a lot to talk about, it's like going to the gym. I just go. I show up every week no matter what. And I think that's really good and healthy, especially if you have a therapist who you think cares about you and is invested in you, and you can just talk about, you know, life. And I'll tell you, sometimes when I go and I don't have anything bothering me or an agenda is when I do the most important work in those sessions, sometimes, so you just never know. But talk therapy is great, but it can only go so far. The conscious mind really gets in the way. Finding someone who cares is difficult the right credentialed person is expensive. A lot of the best people typically don't take insurance. It's not true for all of them. There's wonderful people out there who do, but a lot of the really good ones don't, and so it's a tough thing, but it has its limitations, like with anything. Ketamine and other psychedelic medicines, because ketamine, for all intended purposes, really is a psychedelic, and it's really the only legally available psychedelic in the United States, has the ability to really dissolve these barriers that get in our way. It helps people to get out of their own way and with exponential growth in ways that really are not possible and haven't been seen in any other treatment or modality. And the way it does that is really two primary mechanisms of action. The first is the neuro chemical effects and what's going on in the brain and how ketamine is impacting the brain and our neurochemistry in ways that really nothing else does. And the other is the experiential component, psychologically, what is going on during the experience or the trip that people have when they're receiving this medicine. And both of those are profound and really create lasting impact. On the neuro-chemical level, there's a neurotransmitter called glutamate. It's the most abundant neurotransmitter in the brain. It's present in 85% of the brain. All the other neurotransmitters combined comprise only 15% but for some reason, we've been disproportionately focused on them with mental health treatment. Those are the common ones you know of. Serotonin, dopamine, norepinephrine, you know, the most common class of antidepressant medications are SSRIs. Those are selective serotonin reuptake inhibitors, and those are targeting serotonin. They're a tool. They help some people. They really don't help a lot of people, too, and the people they do help, they really cause a lot of negative side effects and weight gain, sexual dysfunction, dried mouth, blurred vision, even increased suicidality, and the list goes on and on, really terrible side effects that are really debilitating for a lot of people. Even when those side effects are not as debilitating, the quality of relief is typically not very good. So people will say, oh, well, I definitely am not as depressed, but I don't feel happy either. I'm just kind of existing. They have the spectrum of life and of the human experience narrowed, so the lows are not as low, but they're not really thriving either. Not a nice place to be. Is it better than being in bed all day? Absolutely. But that's not the goal. That's not my goal for my life. That's not my goal for other people's lives and for the patients who come to our clinic. We want people to really thrive. Ketamine has the ability to help people to truly thrive. It restores compassion for self and others. It is enhanced energy and motivation for most people. It's a genuine reconnection of self. One of the things that happens with this, with the glutamatergic system and other processes that are occurring in the brain with IV infusions of ketamine, is it causes and promotes neurogenesis, enhanced neuroplasticity, actual new pathways, new connections forming in the brain. This helps people to form new habits, new patterns, new ways of thinking and being that can be very, very positive by disrupting a lot of the automatic responses and reactions we have in our day to day life that get so deeply enmeshed in us that they become a part of our personality, and ketamine can kind of push the reset button on that so that we have the opportunity to consciously choose who we want to be and how we want to be, and helps us call into question the things that we've accepted as just that's the way that I am, or that's the way that it is, and that's not the case most of the time. You look at trauma, for example, ketamine is extremely helpful for depression and anxiety, but also for PTSD, and a lot of people have some trauma that is at the root of one of those issues, and ketamine helps people to recraft the story around that trauma. So what happened is fixed and can never change. The past is the past, but our stories about it can change at any given moment, who we are and who we were and the other people and our role in it, and their role in it, and what happened and what didn't happen, and ketamine provides this kind of objective clarity on that that can be extremely healing and transformational for people.Lesley Logan 9:50 Yeah, this is fascinating. What I've known about ketamine, and I have friends who, I have a holistic doctor friend who offers it as a treatment, and I've heard of these amazing effects that can happen, but I never understood on the brain level, like what's going on and why it's different than the antidepressants that people are on, and how it could, so if someone comes in, first of all, what are some of the reasons why they're coming in for treatment, and then what is the, what are the expectations? Are they coming in one time for an IV infusion? Is this a weekly thing? And how long can the effects last? Can it be forever? Do they have to keep coming back? Can I get the lowdown on that? Sam Mandel 10:25 Yeah, you're asking all the right questions. So what treatment looks like is typically a series of six infusions over two to three weeks after that process I just explained where people are cleared for treatment. They come in, we have them fill out some paperwork, do a brief physical exam, and they come back to a private room. We help them to become comfortable in a recliner with noise canceling headphones, a sleep mask, unlimited selection of relaxing music, pillows, blankets, and we start an IV, and then we infuse the ketamine for 50 to 55 minutes. And it's a slow, gradual, steady state of infusion. People are conscious and awake the entire time. There's a level of dissociation where we don't want them to go so far that they don't know what's happening, but we want them to go into it far enough that they can kind of have a little bit of that quieting of the noise and chatter in their minds, and get a little bit of that clarity that I was describing earlier, and this separation really from themselves in a healthy way to take a look at things that can be really therapeutic, and doing that inner work. We monitor them the whole time. We use hospital-grade monitoring equipment. So that's like pulse, oxygen, EKG, blood pressure, continuous monitoring. I mean, it's a very safe medicine when it's used responsibly in a clinical setting like Ketamine Clinics Los Angeles. We still do all the proper monitoring just to make sure that people are comfortable and safe. And yeah, it's, that's pretty much the, you know, summary of the experience.Lesley Logan 11:53 Yeah, no. Thank you for sharing that, because I think, I don't think anyone's ever explained that, and I'm trying to think about people listening. It's like, well, what does it look like, you know, because let's just talk about what, we have heard about ketamine in the news lately, and it will continue to be in the news as people are going on trial, like when we hear Matthew Perry pass away from not the best use of ketamine, I think people are like, well, then how do you, what does it look like? Am I doing this myself? And I love that you have a wonderful protocol that allows people to be safe and use it in the best way that gets them the best results. But can we talk about the dark sides of ketamine, and what are some signs that people might not be in the safest situations using ketamine?Sam Mandel 12:30 Yeah, well, I'll definitely answer that with your reference to Matthew Perry, which is obviously a really sad situation. He was taken advantage of by people he trusted. He was a addict. He had a really, he's really struggled with addiction. He was very public about that, and not with ketamine specifically, but with really any substance that he could get his hands on. And was in a lot of pain, obviously, and it's a terrible situation. I think it's really important that people understand, though, that that has nothing to do with ketamine therapy. And the media created a lot of confusion for people saying that he had had ketamine therapy a few weeks ago and but that wasn't really a part, a factor in his death. But by the way, he had that and, you know, saying that he died from the acute effects of ketamine, that's just it was really, really distorted. He took more than 10 times the dose of ketamine that we give in the clinic by himself, in combination with buprenorphine, which is essentially an opioid, and Lorazepam, a benzodiazepine, which is another sedative. So he's combined three powerful sedatives, one of them in really absurd doses, by himself in a hot tub. And of course, what happens? He becomes incapacitated and he drowns. This is not, this is such a departure from what we do when we use ketamine in a therapeutic context. There's no correlation, but the way that it's been reported on, and what the average person hears is, oh, ketamine is a bad, dangerous drug, and that's it. That's the takeaway, and that's really a sad thing for people to to get from it. What they should get is that addiction is a serious illness. What they should get is taking lots of sedatives in combination is dangerous. Taking drugs unsupervised, alone in a hot tub is dangerous. These are the takeaways. There was even medical doctors involved in supplying it to him, but they were part of an illicit, underground, illegal drug ring. You know, this is not like mental health care, you know?Lesley Logan 14:25 I know. It's so sad because, well, first of all, the whole situation is sad. It's sad that someone was taken advantage of. It's sad that someone died from combining too many things, but also because they had doctors doing it, like all of that is sad, and, but, really, what I find, and one of the reasons I wanted to talk with you is, so this podcast is called Be It Till You See It, and one of the things that I am always on a search for is like, what can keep us from being it until we see it, what's holding us back in our life, or what can help us more? And the facts of what ketamine therapy that you do that is supervised, and you have pre-screened people to make sure that this is the right therapy for them, the benefits can actually change people's lives, like you said at the beginning, to choose what they want, and that allows them to step into the person that they want to be, like to me, this can be an amazing option for people who they know what they want, but they are just stuck, and they've got other things going on that with their mental health that the talk therapy hasn't helped with, or antidepressants haven't helped with. And so I really wanted to, like, clear the air and go, this can be an option for the right person.Sam Mandel 15:30 Absolutely and I'm really grateful for the opportunity to speak with you and for you creating a platform to have conversations like this, because people deserve to know the truth. And you know, you talk about talk therapy. I mean, a number of patients have literally said that was like 20 years of therapy in an hour. I mean, it really is that exponentially transformational. And it's not instead of therapy, but in addition to, right? When you can do a treatment like this and then work through the material and the learnings that come up for you with someone who understands mental health, who you trust, that's where a lot of even more growth can happen, and you can implement those learnings into your day to day life in the weeks to come. That process is usually referred to as integration, and it can look a lot of different ways, but then you have your experience. How do you integrate it into your life and actually make lasting change? Ketamine really does produce transformation for most people. In the almost 11 years that we've been doing this, we have done over 30,000 infusions. We have an 83% success rate, and we're typically not seeing people who are just wanting to have growth because they're stuck. We're seeing people who have treatment resistant depression, complex PTSD, severe anxiety, suicidality. I mean, there are definitely more moderate cases, but we see a lot of people have really just they've tried a lot, and some of them tried everything, and they haven't benefited. And this really works for them, because it works on under a completely different mechanism of action than the conventional treatments like antidepressant pills or even ECT or talk therapy, or really anything else out there. Lesley Logan 17:04 Yeah, when I think about PTSD, we obviously a lot of things about vets. People have been in the military, but there are people with PTSD who have had other traumas. It doesn't have to be that you've been to war. You could have been in a bad car accident, you could have been assaulted. Can you kind of explain and maybe it's redundant, but just how does ketamine help with PTSD, and then what does someone's life look like? What with one, do you have a case that a person who you can talk about, like, who had PTSD and like, what their life was like after the ketamine treatment? Sam Mandel 17:29 I'm glad you bring that up, because while a lot of us do think of military and war, there's actually many more cases of PTSD among the civilian population in the examples that you mentioned with violence, assault, accidents, etc. So it's super common, unfortunately. I believe there's around 16 million Americans suffering from PTSD who are at least diagnosed. There's many more, I'm sure, who are undiagnosed. And ketamine really does help with the neurochemistry in the brain and helping to rewire the brain, and it also really helps with the perception that we have of ourselves, of the event. People who have trauma are able to go back and revisit the trauma without being as emotionally triggered by it. And so sometimes, when I've talked about this with you know, friends, they say, yeah, you can revisit your trauma and work through it, and it's so great. And they're like, whoa, whoa, whoa. Why would I want to revisit my trauma? What are you talking about? I'm going to go and spend time and money to go there? No, thank you. I spent time and money avoiding my trauma, not going to visit it. But it isn't like that. You know? There's this ability to work through it without having the kind of pain of going there that is so often keeping people from addressing it head on in talk therapy and in life. We avoid, naturally, what's painful, but it isn't painful for most people in this context, they're able to have this detachment that is healthy in this way, to revisit it and to understand who we are, who we were, what our role was, what It was and etc, and to get clarity on that. And it can be really healing. It can really provide closure for a lot of people. And just with the whole cascade of different chemicals going on in the brain, it gives people generally a better mood and more positive outlook and demeanor, and enhanced feelings of compassion towards oneself and towards others and energy and motivation and just all around wellness, it's an elevator in that way which can just be really motivating for people to be able to do the things that most of us know we need to do and just struggle with in terms of our lifestyle, like fitness and eating healthy and sleeping well and talk therapy and having healthy relationships with people, getting outdoors and getting some sun and some fresh air, doing things we enjoy, all that stuff is absolutely critical for longevity, and for someone who's really severely depressed or anxious or dealing with real trauma, they can also feel like it's almost impossible to do a lot of those things. Lesley Logan 20:00 Yeah, yeah. You know, it's really interesting. If you're not someone who has PTSD, or you haven't had, like, severe depression, it can be hard to understand that it becomes all encompassing, you know? But if you think about it, like, when you've had an injury, you've been sick for a few days and you can't leave the bed, that's the the domino effect of what happens to your strength, and then what happens to your ability to, like, feel like you can reach out and that you can connect with people because you've been sick for a week. It's an easy way to see like, oh, if that's my life all the time, you know, it's not easy to go outside, and it doesn't feel easy to connect with people. And so it becomes part of their whole life. And so it's really cool to hear that with ketamine treatments over a couple of weeks that they could have a new lease on life and enjoy it. And I love that you brought up longevity, because I think we forget that how we treat our bodies now is what dictates how long will you get to have them? Hopefully, there won't be anything that stops us from living the life that we're supposed to but if you don't see like a lease on life there, what longevity do you have, you know, so it must be really amazing to get to do what you do every day. You really help so many people.Sam Mandel 21:01 I love it. It's the most gratifying thing ever, you know. When I tell people a lot of my job, the reality of what I do on a day to day basis, I have to do a lot of things I don't like to do, I don't want to do. I'm the CEO of my company. I get the worst, toughest problems that no one else can deal with. I get the fires to put out, the problems, the issues that got escalated to me, and all the weight and pressure and responsibility of it, and there's a lot of stuff, this is not fun, frankly, but I do it because of the, for the patients and for my team, and the work that we're doing, the impact that we're having. It's hugely motivating and gratifying. And when I see patient who I pass in the hallway in the clinic, and they just, can I just give you a hug, or I just want to say thank you so much, or we get a new Yelp review, and someone goes through and lists, you know, half my team by name and how amazing each one of them is, and how life-changing this has been for them. That's what gets me up in the morning, and that's what helps me to keep going every day. I just love it. The transformations are very abundant. And, you know, like I said, 83% it's not magic. It doesn't work for every person every time. It's not perfect, but it is a really incredible treatment.Lesley Logan 22:04 Yeah, yeah, I do understand that. I mean, my husband and I run our own businesses, and sometimes you can forget what you do while you're doing it, because you're doing all the fires, yeah? But then you do get stopped by someone who's been helped by it, or their life has changed, and you're like, oh, that's why I do this. Obviously, you know, it's been a journey to get to do this. Can you take us back how you figured out how to create a space where people could have ketamine therapy? You know, you are the first in the country. So, like, there wasn't really a model to go off of. So I feel like there's a be it till you see it story in there.Sam Mandel 22:36 Oh yeah. Started with me building the website with GoDaddy website builder, drag and drop modules, not knowing a lick of code, never built a website or anything of the sort, not even the most tech savvy guy, and literally just dragging and dropping and, you know, doing research on articles and clinical research, and conferring with my father, who I co-founded the practice with. He's a physician, and I'm talking about, what do you think about this? I'm just trying to make sense of it all in a way that I could understand it well enough to then be able to put it into layman's terms and explain it to other people. What is this? How does it work? And just putting it together, and then going to Radio Shack and getting a motorLesley Logan 23:17 That's how long ago this is because I don't even think they're around anymore.Sam Mandel 23:20 They're not, They went bankrupt. Lesley Logan 23:22 Was it the Radio Shack on Santa Monica Boulevard underneath the yoga place? Because that was my favorite. Sam Mandel 23:27 It was the Radio Shack in Marina Del Rey by the CVS and little strip mall off of Max Stella or something. Anyways, I got a Motorola flip phone prepaid, and I said to my father, you ready to launch the site? We're going to make it live. And made it live, and started taking calls on this cell phone. We were renting space in another doctor's office that was literally this closet. No kidding, they used it as a utility closet before we rented it, and once we moved out and got our own space. They went back to just keeping boxes in there. That's how tiny this room was, no kidding, and it was just really a trip. We had a operating room, recovery area, recovery room for an OR right outside of that little closet that we were in, which, by the way, we were sitting at literally just two folding chairs, a folding table with two laptops, and that was it, no kidding. And we use this recovery area to see patients. And we saw our first few patients, and their transformations were so incredible. We went, this is just too special. We have to do whatever it takes to do more of this. And my father was working as an anesthesiologist. He also has a master's degree in psychology. He was chief of anesthesia in this plastic surgery suite where we were. And so it started out with, well, he's already there, doing anesthesia for the surgery. Maybe we see a couple patients here or there, see how it goes. And next thing we knew, we just started getting busier and busier. The word got out. This was such a radical thing that a lot of people were very incredulous, very suspicious. A lot of people were very critical, but we were like, it doesn't matter. I mean, this is just too special. And it got to the point where my father had to choose between doing our cases or doing ketamine infusions for patients. And I, I remember that quite vividly, where I said, it's really gotta pick. We can't continue to do both. And it was a big risk, you know, it was a really big risk. So I have a lot of respect, you know, for him, for that and that we both just said, let's be all in on this. And, you know, we bootstrapped it. We put everything on credit cards. We had no investors, no financing, no loans, nothing. It's just a little bit of cash, credit cards. And really, just brick by brick, built it up, and now we have 15 employees, 5000 square feet, a really beautiful purpose-built office. I still have, well after the falling table, I had a custom desk built because of maximizing every inch of that space. So I had, there was a little nook between two pillars in that room, under a window, where they made this skinny little desk that was probably literally eight inches wide by three and a half feet long or something. Just stick it in this little nook so I could sit at a proper desk, and I still have that here in our suite now, and so that's kind of fun, but, yeah, it's just truly been an incredible journey.Lesley Logan 26:12 I thank you for taking this back, because we do have a lot of people who are entrepreneurs, and I think that they need to hear that like even a ketamine clinic, the first of its kind, starts in a utility closet. You know, people don't realize, because if you, one, you have to know if people want the thing. You knew it was great. You knew it could be amazing. But you have to get people to buy in, and especially on something that long ago, where people might not know all the amazing things that it can do. And even today, now, even with a beautiful space that can attract people in and make them feel super safe, doing something that changes lives, but also going up against where misconceptions, misinterpretations, and also the people who are misusing it can affect the majority getting the help that they need. I love hearing the stories of how things come to be. And also that is pretty amazing that your dad was like, yeah, I'm gonna quit my safe job. There's always gonna be surgeries, you know. So that's so, so, so cool, and it's really amazing. Is there anything about ketamine therapy that I haven't asked you, that you want to make sure people know? Is there anything else that we can help people understand why this would be something they might need to use, or might use so that they can have the life they want to have?Sam Mandel 27:19 Yeah, I do want to mention, you know, I was talking about how, you know, Matthew Perry was misusing it, and how different that situation is from what we do. And ketamine is still something that people do use recreationally or abuse or misuse. It's not as common, I think, as sometimes it's portrayed, but it definitely can happen, but it's also not in the same category as most other substances, because ketamine is not addictive in the way that most others are. And what I mean by that is you don't develop a physical dependence on it if, for example, like nicotine or opioids or alcohol or benzodiazepines, all you can get to the point where you actually need it to not feel sick. I mean, you have physical symptoms of feeling like nausea, headaches, wanting to throw up. Even with benzos, you can actually, if you abruptly stop taking high doses, you can literally have seizures and die. And you know, you can have symptoms from abrupt cessation of alcohol if you're a heavy alcoholic. That doesn't happen with ketamine. So some people can use it in the way that they're using it as a means to escape, but that's not really that different as far as the psychological dependence in the way that someone can use ice cream or chocolate or, you know, sour candies or sex or any of these other video games as a means of escape or avoiding or to self-soothe. So I think it's important that people understand that. It also has a very, very high therapeutic index. There's actually no known lethal dose of ketamine, so you can obviously be in a bad, unsafe environment, where, if you take a bunch and get into a car, that's not a not such a great outcome for you, or in a jacuzzi, but the medicine itself is unlikely to hurt you on its own. Most of the issues are people in bad situations, or they're combining it with other drugs. Virtually, almost all of the fatalities that are related to ketamine were one of those two, either in combination with other drugs and or in a situation like behind the wheel of a car. So I just want people to know that it's not to say that there aren't people who have an issue with misusing ketamine, because there are, but it really is distinct from most other substances that people are misusing or abusing.Lesley Logan 29:20 Thank you for saying that, because I do think, as a child of the night, you know, I grew up in the 80s, so it's, like, always just say no to drugs. Sam Mandel 29:25 The cocaine epidemic. Lesley Logan 29:28 Yeah, so I know they really that didn't really help them, did it? But, like, they thought it would. But I, like, grew up, so it's really funny when I have friends who, like, talk about doing some sort, some psychedelics, or do I have this innate like, I don't, I don't know, I don't know if I could do that. I'm afraid to try. I'm like, I'll be addicted on the first dose. Sam Mandel 29:45 Right, right, right. Lesley Logan 29:47 This is my fear, which is why I drink, right? That's what people do. And so they said no to drugs, but then they drink. But I really appreciate because it's nice to know that if I were to do a ketamine therapy, I'm not going to be dependent on coming to ketamine therapy every single week or I'll be using it at home, like, it's nice to know that it's a non-addictive thing that people can use to get the benefits. And I think that can make a lot of people feel more comfortable, you know. Sam Mandel 30:08 Yeah, because people are afraid of that, they think, God, well, if I go and do this, even if it's in a therapeutic way, am I going to become a ketamine addict? You know? I'm going to go and then be looking to score some on the street the next day. It's really a sad perception that some people might have due to the media or for whatever reason or they know somebody who misuse ketamine or the DARE program, like you said, or the 80s. A lot of baloney. Lesley Logan 30:28 Oh, and by the way, the DARE program was a lot of baloney. I just heard a whole podcast about it, and I was like, ah. So, but it, but it does put in people's minds, and also good for good reason. Like, I don't want people going out there doing other drugs we do know our addictive and like, hoping that they are fine out there the first time, but I am on this mission of helping people figure out how to get out of their own way and live their best life, and sometimes our own way are things that are really outside of our control, the PTSD, the depressions, the mental health, the suicide like I think it's important that people have access to forms of therapy out there that they may not know about or they may have misconceptions. Because we do know that the media does like to click bait things into headlines that get people to look at them, but don't actually give all the information. So I'm just so grateful that you were here to just really explain all this and the benefits of it.Sam Mandel 31:22 Absolutely, yeah, no, I appreciate the opportunity. Yeah, there are drugs that you can do once or twice and develop a real serious problem with pretty fast, methamphetamine, probably not one that you need to ever try. You know, if you're curious about trying drugs, I'd say take that one off the list. Heroin, probably not a good idea. Pretty easy to die, pretty easy to get addicted to that one, right? Opioids, crack, cocaine. These are some that maybe you don't need to, you don't need to check out, but maybe there's some others that if you really want to with the right mindset in the right context, if you're going to be safe or responsible, maybe you'd be okay with. And by the way, I'm not advocating for you to go do illicit drugs illegally either. But there are some that you can have, even in a controlled environment, such as ours, where you don't need to be afraid of them. I'll tell you what are the most dangerous, though, is the prescription legitimate drugs. As a matter of fact, prescriptions are more commonly abused than any of the other illicit drugs. You look at your stimulants like Adderall, your benzodiazepines, like Xanax, opioids, I mean, these are drugs that are a lot of people are really hooked on and that are killing a lot of people, especially the opioids, but because they're from big pharma, they're not all that bad. I mean, people are finally starting to scrutinize the opioids, but the others are still kind of under the radar, and they're really widely abused, but the focus is on the big, bad, illegal ones. Lesley Logan 32:39 I know of a client who's a social worker, and she used to work in a hospital, and we're talking about pain meds, and she's like Lesley, I watched a 14 year old kid come in super healthy, just had a broken arm. They had to have surgery, but within the three days they were there, they were extra tapping the pain meds. And she's like, we create addicts with these pharmaceutical drugs quickly, but we don't think of it like that, because they had a prescription written. And so it's important for us to educate ourselves, to be informed and to be able to advocate for ourselves or advocate for others when we have this information we can. So, thank you so much. I'm not gonna let you go. We actually are gonna take a brief break, and then we're gonna find out Be It Action Items from you. Lesley Logan 33:19 All right, Sam, where can people find you, follow you, connect with you. If they want to know more about ketamine therapies, if they want to come to your clinics, how can they connect with you best?Sam Mandel 33:28 Yeah, so ketamineclinics.com. That's K-E-T-A-M-I-N-E-C-L-I-N-I-C-S dot com. Lots of great information on there. People are more than welcome to call us, 310-270-0625. Consultations are free. We're always happy to chat see how we can help you. We do offer other treatments we really didn't talk about today, TMS, General Psychiatry, medication management, we take 12 of the biggest insurance networks in California, including Medicare, so there's a lot more that we can cover with you. Whether or not ketamine is the right fit if you are dealing with a mental health condition, I would encourage you to call and see if there's anything we can do to help. And we're on social it's ketamineclinicsLA on all socials and my personal is theSamMandel on all socials. And just really happy to connect with people and hear their stories, answer questions and help in any way that we can. Lesley Logan 34:23 I love it. Thank you. And that's also so cool, because we mentioned, like, it can be really hard to find a therapist these days because they don't always take insurance. So to hear that you do. It's really nice. Okay, we always ask people bold, executable, intrinsic or targeted steps they can take to be it till they see it. What do you have for us?Sam Mandel 34:41 Oh, I wasn't ready for that one. I would say action. Take action. Just do it. Take Nike slogan. I mean, honestly, planning and strategizing is important, and thinking things through and figuring out who you are. What you want, what you like, what you don't like, putting together a plan matters. But I think most of us, or almost all of us, spend too much time on that, and there's just too many unknowns and too many things that you really can't solve for until you're in it and doing it, and it's too easy to let perfectionism keep us from taking the steps that we need to take to get done what we want, become, who we want to be, and who what our potential is. And I personally struggle with this too. So I say that from, you know, my own experience, and I really strive, and I want to encourage other people to really strive, to just get out there and do it, and you're going to make mistakes, and that's okay, but it's really the only way to succeed in life. You have to be on the fields, on the court, in it, and behind the scenes, thinking, planning, strategizing is only going to get you so far.Lesley Logan 35:58 Yeah, yeah. Oh, thank you for that. And also, I can tell you, practice what you just preached, because it's true. You started with a utility closet and some folding chairs and a Motorola phone, I mean. But also, you're correct. People do spend too much time in the planning, or they're waiting for it to be perfect, or they're waiting for the perfect decoration, and then they have the perfect branding and all the things. And if you guys had done that, you wouldn't have been able to help the thousands of people that you have today. So thank you so much, Sam for being here, for educating us, for informing us. Lesley Logan 36:29 And, you guys, how are you gonna use these tips in your life? Please share this episode with a friend as you hear conversations come up about the misuse of ketamine, and now you know you could share this with them to educate them, and also, if you have friends and family or yourself who needs this, please contact Sam and his team, because there's help out there for you. Until next time, Be It Till You See It.Lesley Logan 36:50 That's all I got for this episode of the Be It Till You See It Podcast. One thing that would help both myself and future listeners is for you to rate the show and leave a review and follow or subscribe for free wherever you listen to your podcast. Also, make sure to introduce yourself over at the Be It Pod on Instagram. I would love to know more about you. Share this episode with whoever you think needs to hear it. Help us and others Be It Till You See It. Have an awesome day. Be It Till You See It is a production of The Bloom Podcast Network. If you want to leave us a message or a question that we might read on another episode, you can text us at +1-310-905-5534 or send a DM on Instagram @BeItPod.Brad Crowell 37:33 It's written, filmed, and recorded by your host, Lesley Logan, and me, Brad Crowell.Lesley Logan 37:38 It is transcribed, produced and edited by the epic team at Disenyo.co.Brad Crowell 37:42 Our theme music is by Ali at Apex Production Music and our branding by designer and artist, Gianfranco Cioffi.Lesley Logan 37:49 Special thanks to Melissa Solomon for creating our visuals. Brad Crowell 37:53 Also to Angelina Herico for adding all of our content to our website. And finally to Meridith Root for keeping us all on point and on time.Support this podcast at — https://redcircle.com/be-it-till-you-see-it/donationsAdvertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy
Part 3 with Carnivore JT! JT is a former Division 1 Baseball Coach turned advocate for the carnivore diet. With a B.S. in Sports Medicine and M.S. in Sports Administration, he hosts "The Inner Carnivore Podcast," where he explores the benefits of a meat-only diet, shares success stories, and challenges conventional nutrition wisdom. He's also the author of "The Carnivorous Cookbook." A great podcast on a fascinating topic, we hope you enjoy!00:00 Extreme results of carnivore diet06:05 Future of carnivore diet and are any doctors advising?10:30 What does JT do for work?13:45 Impossible to get fat eating carnivore?!17:00 Gut microbiome / prebiotics / fermented food20:15 Serotonin and gut health23:00 Problems with prescriptions 29:00 Doctors conundrum 35:00 Dealing with haters
What if you could tap into your child's natural brain chemistry to boost motivation and reduce stress? Discover the "Happiness Quartet"—four key neurochemicals that can transform behaviour, learning, and family life. From barefoot walks on grass to risky play, learn practical ways to naturally boost these powerful brain chemicals for happier, more motivated kids. Quote of the Episode: "Break big, difficult tasks down into smaller, more manageable steps - each step triggers a dopamine hit, which fuels motivation and sense of accomplishment." Key Insights: Dopamine works as an anticipation engine Serotonin acts as a natural stress reducer Endorphins serve as natural painkillers Oxytocin builds trust and connection Nature exposure boosts multiple positive chemicals Physical activity enhances brain chemistry Social connections trigger beneficial hormones Breaking down tasks increases motivation Resources Mentioned: Neuroscience research on motivation Serotonin and nature studies Happy Families Action Steps for Parents: The Dopamine Boost Break tasks into smaller steps Celebrate progress Create anticipation The Serotonin Solution Get outside in nature Try barefoot grounding Practice deep breathing The Endorphin Lift Encourage physical activity Make time for laughter Allow calculated risks The Oxytocin Connection Prioritise family meals Share physical affection Create trust-building moments See omnystudio.com/listener for privacy information.
Bob Colling Jr. & Dallas Gridley continues their journey with the hundred-and-forty-first episode of TNA iMPACT! from March 8, 2007 on Spike TV at the Impact Zone in Orlando, Florida. Kurt Angle teams up with Samoa Joe & a mystery partner to take on Christian Cage, Tomko & Scott Steiner! Plus, Jay Lethal, Petey Williams & Sonjay Dutt are in 6-Man Tag Team action against Eric Young, Robert Roode & James Storm! Also, Voodoo Kin Mafia, Serotonin, Raven, a message from Sting, Abyss interrupts a special ceremony to introduce the newest member of the TNA family and so much more just days before Destination X! Join us now before the next big PPV event! More TNA Cross The Line Podcast: tnacrosstheline.com Follow us on Twitter @CrossTheLineTNA Follow us on Facebook @TNACrossTheLinePod Follow us on Instagram @CrossTheLineTNA Subscribe to our YouTube Channel Shop at our Pro Wrestling Tees Store
Story at-a-glance Negative ions are electrically charged molecules that concentrate naturally in areas like beaches, waterfalls, mountains, and forests, that help cleanse the air of unhealthy particles Scientists have found that high-density negative air ionization may help counter symptoms of seasonal affective disorder (SAD) The ocean's negative ions are created when water molecules gain electrons, while mountain air can be rich in negative ions due to mineral content like magnesium and calcium from limestone Taking a shower can generate negative ions at home through the "Lenard effect," where the shearing forces of fast-flowing water create friction that adds electrons to molecules Negative ions form when oxygen in the air (O2) takes on a negative electrical charge to become O2⎺, which then gets enveloped by microdroplets of moisture to create what we know as "fresh air"
In this Huberman Lab Essentials episode, I discuss the biology of emotions and moods, focusing on how development and neurochemicals shape our feelings and relationships. I describe how early infant bonds and puberty shape adult patterns of emotional connection. I explain that understanding emotions requires recognizing both internal states and external cues, along with strategies to enhance your emotional awareness. Additionally, I discuss the key elements of healthy emotional bonds and provide practical tools to deepen one's understanding of emotions, leading to a richer emotional life. Huberman Lab Essentials are short episodes (approximately 30 minutes) focused on essential science and protocol takeaways from past Huberman Lab episodes. Essentials will be released every Thursday, and our full-length episodes will still be released every Monday. Read the full episode show notes at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman Eight Sleep: https://eightsleep.com/huberman BetterHelp: https://betterhelp.com/huberman LMNT: https://drinklmnt.com/huberman Timestamps 00:00:00 Huberman Lab Essentials; Emotions 00:03:01 Sponsor: Eight Sleep 00:04:39 Emotions & Childhood Development 00:06:35 Infancy, Anxiety 00:08:04 Understanding Emotions; Tools: Mood Meter; Emotions & 3 Key Questions 00:11:45 Infancy, Interoception & Exteroception 00:12:48 Sponsor: BetterHelp 00:14:02 Strange-Situation Task & Babies, Social Bonds, Emotional Regulation 00:18:04 Tool: Exteroception vs Interoception Focus? 00:23:07 Sponsor: AG1 00:24:11 Puberty, Kisspeptin; Testing the World & Emotional Exploration 00:31:56 Sponsor: LMNT 00:33:13 Creating Healthy Emotional Bonds; Dopamine, Serotonin & Oxytocin 00:37:07 Vasopressin; Vagus Nerve & Alertness 00:41:34 Recap & Key Takeaway Disclaimer & Disclosures
In my show with TJ Powers, talking through his book, The DOSE Effect: Optimize Your Brain & Body By Boosting Your Dopamine, Oxytocin, Serotonin, and Endorphins, he lists out 20 activities to address all those brain chemicals, and I want to give it to you, whether you buy the book or not. If you can add just one to your day, you've at least done that to advocate for your mental well being and overall capacity. I'm thinking about looking at it every morning, then going through it as a checklist in the evening to see how I did. Let's talk through it now. Sign up for your $1/month trial period at shopify.com/kevin Go to shipstation.com and use code KEVIN to start your free trial. Use my promo code WHATDRIVESYOU for 10% off on any CleanMyMac's subscription plans Learn more about your ad choices. Visit megaphone.fm/adchoices
In our culture today, the concept of “slowing down” has little attraction. We are enamored with speed. So instead of trying to sell “slowing down” let's look at what the point of questioning our speed is. Imagine going to hike the Grand Canyon. Or another nearby attraction, Las Vegas. And imagine if your goal is speed. Do you want to just get through either of them as fast as you can? Or would you rather explore and experience what they have to offer? Now come back to our lives in general. Forget the idea of slowing down. I'm questioning our societal quest for tech and AI and travel to continually speed us up. What is the point? Is it working? Are you getting happier as a result? Let's talk. My muse for this discussion is from my recent conversation with TJ Powers and the message in his new book, The DOSE Effect: Optimize Your Brain & Body By Boosting Your Dopamine, Oxytocin, Serotonin, and Endorphins. Find TJ on Instagram @tjpower. In our culture today, the concept of “slowing down” has little attraction. We are enamored with speed. So instead of trying to sell “slowing down” let's look at what the point of questioning our speed is. Imagine going to hike the Grand Canyon. Or another nearby attraction, Las Vegas. And imagine if your goal is speed. Do you want to just get through either of them as fast as you can? Or would you rather explore and experience what they have to offer? Now come back to our lives in general. Forget the idea of slowing down. I'm questioning our societal quest for tech and AI and travel to continually speed us up. What is the point? Is it working? Are you getting happier as a result? Let's talk. My muse for this discussion is from my recent conversation with TJ Powers and the message in his new book, The DOSE Effect: Optimize Your Brain & Body By Boosting Your Dopamine, Oxytocin, Serotonin, and Endorphins. Find TJ on Instagram @tjpower. Learn more about your ad choices. Visit megaphone.fm/adchoices
I'm a very visual guy, so I often think of visual analogies to help me better conceptualize a concept. So imagine you are watching a video tape of yourself, sped up to show all your activities for a day. With special attention on how much time you are looking at screens and what you are looking at. How many times do you look at your phone? How many times on your computer are you viewing social media or entertainment or even just random information or news updates? Let's call it non-productive viewing. Do you resemble a contemplative, thoughtful, focused person? Or an addicted squirrel? I'm going to bet you are far more squirrel-like than you'd expect. I believe I am, and my recent talk with TJ Powers about how we build up and deplete our brain chemicals really has me considering this. Let's talk through it a bit. TJ Powers' new book is my muse, The DOSE Effect: Optimize Your Brain & Body By Boosting Your Dopamine, Oxytocin, Serotonin, and Endorphins. Find him on Instagram @tjpower. Sign up for your $1/month trial period at shopify.com/kevin Go to shipstation.com and use code KEVIN to start your free trial. Use my promo code WHATDRIVESYOU for 10% off on any CleanMyMac's subscription plans Learn more about your ad choices. Visit megaphone.fm/adchoices
Episode Highlights With Dr. Erika GrayImportant perspective about genetics and how to use this information for the biggest advantageThe nuance when it comes to children and genes Genes do not exist in isolation and why focusing on one gene is not helpfulHow understanding genetics helped her teens (and mine)What COMT is and how this comes into play with influencing our worldviewFast COMT break down dopamine and norepinephrine faster (linked to moving around, not sitting still, etc.)How this understanding of genetics can relate directly to how we parent Yet another reason protein is so important, especially for kids and teens Genes related to serotonin and dopamine and neurotransmittersWe have 2-5 lbs of bacteria in our gut, and there is a gene called FUT2 that ties to lower levels of bifidobacteria, and this can be linked to anxiety, longevity, and moreUnderstanding choline genes and why this is a game changer for so many people, and this is critical for pregnancy and brain development Some caveat around MTHFR and why we might be overdoing our response to thisSerotonin-related genes to look at if you get your kids' genes testedWhat BDNF genes can tell youMC4R is a snacking gene, and how to understand thisBitter taste receptor genes and how these can make kids more pickyResources We MentionMy Toolbox Genomics - Use code wellnessmama for a discountKion Aminos
Sometimes an analogy comes along that just clicks. It takes information you may have heard before and helps drive it home. That is what happened with my guest in this show regarding the brain chemicals that fuel our drive and motive. TJ POWER is a neuroscientist and innovator in the area of mental health. His work focuses on providing easy-to-adopt, scientifically backed teachings that empower people to take action towards healthier lifestyles. He has a really big following and when I got his book, I understood why. The book is, The DOSE Effect: Optimize Your Brain & Body By Boosting Your Dopamine, Oxytocin, Serotonin, and Endorphins, and in it, TJs explanations helped me see how I am increasing or depleting the brain chemicals I rely on to do the important work in my life. Most of us have heard much about dopamine, but do we really understand how we increase and decrease it? Then also, oxytocin, serotonin, and endorphins. Now the point isn't to understand each one fluently, but to understand how they help us and what we are doing in our everyday lives that help or hurt them. I was most interested in what I learned about how I'm depleting some of these chemicals early in the day, and then later it feels like I'm lacking drive and motivation. I trust in listening to this conversation, you will be able to understand what these chemicals do for us and like me, now understand how to far better leverage them to do the things you truly want to do. You can find TJ Powers on Instagram @tjpower. Sign up for your $1/month trial period at shopify.com/kevin Go to shipstation.com and use code KEVIN to start your free trial. Use my promo code WHATDRIVESYOU for 10% off on any CleanMyMac's subscription plans Learn more about your ad choices. Visit megaphone.fm/adchoices
In this Huberman Lab Essentials episode, I explain the biological mechanism behind motivation and drive, as well as discuss practical tools for overcoming procrastination. I discuss the key role dopamine plays in driving cravings and motivating action. I explain how dopamine regulates the balance between pleasure and pain, and what happens when this system becomes dysregulated, leading to addiction. I discuss the role of molecules like serotonin, which help enhance the enjoyment of the present, and explain how to balance the drive for more while staying focused in the present. I also discuss the causes of procrastination and describe strategies to boost dopamine levels through behavioral approaches or supplements. Huberman Lab Essentials are short episodes (approximately 30 minutes) focused on essential science and protocol takeaways from past Huberman Lab episodes. Essentials will be released every Thursday, and our full-length episodes will still be released every Monday. Read the full episode show notes at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman Eight Sleep: https://eightsleep.com/huberman Mateina: https://drinkmateina.com/huberman LMNT: https://drinklmnt.com/huberman Timestamps 00:00:00 Huberman Lab Essentials; Motivation 00:01:57 Dopamine & Brain 00:04:08 Anticipation, Craving & Dopamine 00:05:37 Sponsor: AG1 00:06:46 Food, Drugs & Dopamine Release 00:10:18 Addiction, Pleasure & Pain Balance 00:14:12 Sponsors: Eight Sleep & Mateina 00:17:14 Dopamine, Pain, Yearning 00:19:08 “Here and Now” Molecules, Serotonin, Endocannabinoids, Tool: Mindfulness 00:22:42 Procrastination; Tool: Extend Dopamine, Offset Pain 00:26:15 Sponsor: LMNT 00:27:31 Dopamine & Motivation; Increasing Dopamine, Phenethylamine (PEA) 00:30:58 Dopamine Schedule, Subjectivity 00:33:59 Gambling, Intermittent Reinforcement, Tool: Blunting Rewards 00:38:51 Recap & Key Takeaway Disclaimer & Disclosures
In this Huberman Lab Essentials episode, I explain how the different nutrients and foods we eat impact our emotions and overall mood. I discuss how the mind-body connection shapes our food choices and cravings, highlighting the roles of key neurotransmitters like dopamine and serotonin in driving eating behaviors. I explain the biological mechanisms behind cravings for specific foods, such as sugar, and how psychological factors like belief effects can influence our perception of hunger. I also describe how certain nutrients, like omega-3 fatty acids, and a healthy gut microbiome are crucial in mood regulation and immune function. Huberman Lab Essentials are short episodes (approximately 30 minutes) focused on essential science and protocol takeaways from past Huberman Lab episodes. Essentials will be released every Thursday, and our full-length episodes will still be released every Monday. Read the full episode show notes at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman Function: https://functionhealth.com/huberman LMNT: https://drinkag1.com/huberman Timestamps 00:00:00 Huberman Lab Essentials; Emotions, Food & Nutrition 00:02:30 Attraction & Aversion 00:03:38 Vagus Nerve, Sugar 00:06:31 Sponsor: Function 00:08:19 Gut “Feelings”, Hidden Sugars, Amino Acids 00:10:43 Dopamine, Craving, L-tyrosine 00:14:45 Serotonin, Carbohydrates 00:17:59 Sponsor: AG1 00:19:36 Tool: Omega-3s; Depression, SSRIs 00:22:36 Gut-Brain Axis, Gut Microbiome 00:26:00 Probiotics, Brain Fog, Tools: Fermented Foods, Saccharine Caution 00:29:03 Ketogenic Diet & Gut Microbiome, Tool: Individual Diet Variability 00:32:23 Sponsor: LMNT 00:33:40 Tool: Belief Effects; Key Takeaways Disclaimer & Disclosures