Podcasts about Serotonin

Monoamine neurotransmitter

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Best podcasts about Serotonin

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Latest podcast episodes about Serotonin

Hörgang
Wie der Darm unsere mentale Gesundheit beeinflusst

Hörgang

Play Episode Listen Later Feb 16, 2026 14:32 Transcription Available


Milliarden Mikroorganismen leben in uns – vor allem im Darm. Dieses Mikrobiom steuert nicht nur die Verdauung, sondern greift tief in unsere Gesundheit ein. Immer deutlicher zeigt sich: Es beeinflusst auch die Psyche. Der Psychiater Martin Aigner erklärt, dass Darm und Gehirn eng verbunden sind. Über Nerven, Hormone und Botenstoffe stehen sie im ständigen Austausch. Besonders wichtig ist dabei Serotonin – ein Großteil dieses „Glückshormons“ entsteht im Darm. Gerät das Mikrobiom aus dem Gleichgewicht, kann sich das auch auf Stimmung und Stressreaktionen auswirken. Studien zeigen: Ein vielfältiges Mikrobiom geht oft mit besserer psychischer Gesundheit einher. Umgekehrt finden sich bei Depressionen oder Angststörungen häufig Veränderungen. Klare Ursachen sind schwer zu benennen – die Forschung spricht eher von Zusammenhängen als von eindeutigen Wirkungen. Ein zentraler Hebel ist die Ernährung. Ballaststoffe, Vielfalt und regelmäßige Mahlzeiten fördern „gute“ Bakterien. Einseitige, stark verarbeitete Nahrung kann das Gleichgewicht stören. Neue Ansätze setzen daher auf Prä- und Probiotika – als Ergänzung zur klassischen Therapie. Noch steht vieles am Anfang. Doch eines wird klar: Wer den Darm versteht, versteht auch die Psyche besser.

Fall in Love with Fitness
The Three Feel-Good Hormones: Dopamine, Serotonin & Oxytocin

Fall in Love with Fitness

Play Episode Listen Later Feb 12, 2026 11:55


If you've ever felt trapped in cravings, emotional eating, or shame after food — this episode is for you.I break down the three feel-good hormones that quietly run your relationship with food, cravings, and self-sabotage: dopamine, serotonin, and oxytocin.This isn't a biology lesson.It's a reframe — one that replaces shame with understanding and control with compassion.Dopamine: The Fast Relief LoopDopamine is the reward hormone. It's released anytime we move away from discomfort toward relief.Stress → foodOverwhelm → wineEmotions → scrolling, shopping, snackingWhen I feel stressed and ice cream makes me feel better, my brain learns that pattern. Over time, dopamine becomes the shortcut — but it never lasts. The body adapts, and suddenly one cookie isn't enough. One glass of wine becomes three or four.This isn't a discipline issue.It's a trained reward loop in the nervous system.Serotonin: Why Joy Starts in the GutSerotonin is the hormone of calm, ease, and steady joy — and 90% of it is produced in the gut.When I'm in protection mode, digestion is no longer a priority. Blood flow shifts, cortisol rises, and healing shuts down. I can eat — but I'm not digesting.This is why protection mode often shows up as:bloatingfood sensitivitiesanxietystubborn weight, especially around the midsectionMy body isn't failing.It's responding to perceived danger.Oxytocin: The Hormone I'm Actually CravingOxytocin is the hormone of love, safety, connection, and belonging.It's released when I'm kind to myself, when I speak gently, when I connect, hug, touch, laugh, and allow myself to feel safe.But when negative self-talk blocks access to oxytocin, my body looks for substitutes.First serotonin.Then dopamine.Food becomes the regulator when love feels inaccessible.Why Shame Comes After the “High”Dopamine delivers fast relief — followed by second-order thinking:guilt, shame, regret, self-judgment.That emotional crash isn't failure.It's the nervous system losing access to safety again.My body was never asking for food.It was asking for connection.The Missing Piece: Safety Before ChangeEvery thought I think creates chemistry in my body.The vagus nerve listens to all of it.When safety comes first:digestion improvesserotonin risescravings softenweight becomes releasableThis episode reframes emotional eating as a nervous-system response, not a character flaw.Key TakeawaysDopamine offers relief, not regulationSerotonin requires digestion and safetyOxytocin is the deepest need beneath cravingsFood becomes the fallback when love feels inaccessibleHealing happens through safety, not controlReflection PromptsWhen I crave food, what feeling am I really seeking?Where am I relying on dopamine instead of safety?How do I speak to myself when I feel out of control?What would it look like to choose kindness instead of correction today?Where can I create more connection — with myself or others?Closing ThoughtYou're not addicted.You're not broken.You're regulating the best way your body knows how.And what it's really asking for…is love.Book your FREE 30-minute Food Freedom Call now and start your journey to lasting change! Schedule here: https://sherryshabanfitness.com/clarityStuck in cravings, stubborn weight, or unwanted eating? Download my free e-Book Calm The Hormones That Drive Cravings and reset your body naturally.Get Your FREE Guide Here: https://sherryshaban.com/hormonesListen to more episodes at www.makepeacewithfood.com/podcast or subscribe to me on Spotify, Podcast, and YouTube so you never miss an episode!Join my Facebook Community: www.myfoodfreedomlifestyle.com Work with me: www.sherryshaban.com/transform Go deeper: www.makepeacewithfood.com Share your biggest takeaway and tag me on Instagram, Facebook, TikTok, LinkedIn

Andrew Huberman - Audio Biography
Dopamine, Serotonin, and Decision Making: Inside the Brain's Reward System

Andrew Huberman - Audio Biography

Play Episode Listen Later Feb 7, 2026 2:38 Transcription Available


Andrew Humberman BioSnap a weekly updated Biography.Andrew Huberman, the Stanford neuroscientist and Huberman Lab podcast host, dropped a pair of fresh episodes this week that have fans buzzing. On February 2, he welcomed Dr. Read Montague to unpack how dopamine and serotonin drive decisions, motivation, and learning, diving into real-time brain scans and AI parallels like AlphaGo in a chat laced with personal anecdotes from their 15-year reconnection, as detailed on the Huberman Lab site and Singju Post transcript. Just days later on February 5, Huberman released an Essentials episode with movement guru Ido Portal, breaking down nervous system tricks for better motion, panoramic vision drills, and playful exploration to rewire habits, straight from hubermanlab.com.Business-wise, Mens Journal spotlighted Hubermans five core health pillars sleep, sunlight, movement, nutrition, and relationships on February 3, pulling from his podcast wisdom to pitch them as no-nonsense basics over trendy biohacks. A viral YouTube short from Iain Barton Shorts that same day clipped Huberman on neuroplasticity focus exercises, racking up views with his tips for daily visual drills to sharpen concentration.Hes also in the medias crosshairs amid the Epstein files fallout. Plant Based News flagged him January 31 as a wellness bro tied to Peter Attia, whose 1700-plus Epstein mentions including flirty emails surfaced recently, though Huberman himself faces no direct links there. Katie Couric Media critiqued on January 28 his CBS News contributor gig alongside Attia and Mark Hyman, slamming their supplement-pushing protocols as overhyped with conflicts, yet CBS kept them post-scandal. Willamette Week noted on February 3 his 2023 podcast collab with Epstein-linked psychiatrist Paul Conti, stirring guilt-by-association whispers. No public appearances or direct social mentions popped in the last few days, but his feeds hum with blueprint emails to over a million subs. Speculation swirls on long-term bio rep hits from the influencer scrutiny, but Hubermans output stays relentless.Get the best deals https://amzn.to/3ODvOtaThis content was created in partnership and with the help of Artificial Intelligence AI

The Ranveer Show हिंदी
LIFE CHANGING EPISODE : Kundalini Activation & Chakras Explained SCIENTIFICALLY I TRS

The Ranveer Show हिंदी

Play Episode Listen Later Feb 6, 2026 197:05


Check out BeerBiceps SkillHouse's YouTube 1O1 Course - https://youtube.beerbicepsskillhouse.in/youtube-101Share your guest suggestions hereMail - connect@beerbiceps.comLink - https://forms.gle/aoMHY9EE3Cg3Tqdx9For all BeerBiceps vlog content Watch Life Of BeerBiceps - https://www.youtube.com/@LifeOfBeerBicepsBeerBiceps SkillHouse को Social Media पर Follow करे :-YouTube : https://www.youtube.com/channel/UC2-Y36TqZ5MH6N1cWpmsBRQ Instagram : https://www.instagram.com/beerbiceps_skillhouseWebsite : https://beerbicepsskillhouse.inFor any other queries EMAIL: support@beerbicepsskillhouse.comIn case of any payment-related issues, kindly write to support@tagmango.comUse my referral code RANVEER to get 1 week of free premium accessDr. Alok Kanojia जी को Social Media पे Follow कीजिए :-YouTube : https://www.youtube.com/@UClHVl2N3jPEbkNJVx-ItQIQ Instagram : https://www.instagram.com/healthygamer_gg/X : https://x.com/dr_alokkanojia?lang=enWebsite : https://www.healthygamer.gg/In this 462nd episode of The Ranveer Show, we are joined by Dr. Alok Kanojia (Dr. K), a Harvard-trained psychiatrist and a former monk, who bridges the gap between modern medical science and ancient Eastern wisdom. This episode takes you deep into the science of Kundalini, the biology of spiritual experiences, and the intersection of mental health and meditation.In this conversation with Dr. K, we talk about the neuroscience behind Chakras, the risks and benefits of Kundalini practices, and how substances like DMT and Psilocybin affect the brain compared to natural meditation. We also explore the concept of the Default Mode Network, the role of Serotonin and Dopamine in happiness, and practical ways to manage ego, narcissism, and confidence. This episode also covers the physiology of specific Chakras (from Muladhara to Ajna), the science of Anandamide (the bliss molecule), the existence of Asuras and Deities, and actionable techniques like Trataka (candle gazing). This podcast is a valuable resource for anyone interested in Psychology, Neuroscience, Mental Health, Spiritual Growth, and understanding the scientific validity of ancient Sanatan Dharma practices.(00:00) – Start of the episode(03:30) – Becoming a Monk at 21(07:26) – Harvard Psychiatry vs. Ancient Wisdom(14:56) – Does Meditation Cure Mental Illness?(19:32) – Kundalini & Enlightenment Explained(23:21) – The Biology of Your Chakras(32:22) – DMT, Ayahuasca & The Brain(38:22) – Serotonin vs. Dopamine: The Science of Peace(47:13) – Why We Are Getting More Depressed(54:13) – Scientific Reason for "Celibacy" Postures(1:02:37) – Why Kundalini Yoga Can Be Dangerous(1:09:38) – The Power of Guru Diksha (Initiation)(1:16:58) – Can Meditation Cause Psychosis?(1:25:07) – Default Mode Network: The Science of Ego(1:31:28) – Narcissism vs.True Confidence(1:38:37) – Observing The "Self"(1:46:37) – Coma Patient Who Lived a Whole Life(1:56:31) – Evidence of Past Lives?(2:03:04) – Confidence is Your Baseline State(2:07:53) – The Truth About Marijuana & Anandamide(2:17:44) – Stop Using "Toxic Fuel" for Success(2:23:53) – How to Work 7 Days Without Burnout(2:36:34) – Happiness Without External Substances(2:39:42) – Meeting Entities on DMT(2:46:51) – Asuras, Demons & The Subjective World(2:57:44) – Do Gods Care About Us?(3:09:11) – Trataka: A Safe Third Eye Practice(3:16:16) - End of the episode

ManTalks Podcast
Your Self-Worth Won't Let You Change - Until You Do This

ManTalks Podcast

Play Episode Listen Later Feb 5, 2026 20:07


I break down why self-worth isn't a motivation problem and why trying to “think” your way into confidence rarely works. I explain how your identity is built from predictable behavioral patterns and how your nervous system resists change that feels unfamiliar or threatening. We dive into the biology behind self-worth, including dopamine, serotonin, and norepinephrine, and how they shape drive, discipline, and resilience. Finally, I lay out practical steps you can use to rebuild self-worth through action, repetition, and new patterns.SHOW HIGHLIGHTS00:00 - Why Self-Worth Isn't a Motivation Problem01:07 - Identity as Predictable Patterns02:37 - The Rider and the Elephant03:56 - Why the Brain Rejects Change05:16 - Self-Worth as a Felt Experience06:59 - Dopamine and Direction07:12 - Serotonin and Self-Control08:21 - Norepinephrine and Resilience09:28 - Why Change Feels Like Death11:07 - Practical Steps to Rebuild Self-Worth14:56 - Self-Worth Is Built Through Action***Tired of feeling like you're never enough? Build your self-worth with help from this free guide: https://training.mantalks.com/self-worthPick up my book, Men's Work: A Practical Guide To Face Your Darkness, End Self-Sabotage, And Find Freedom: https://mantalks.com/mens-work-book/Heard about attachment but don't know where to start? Try the FREE Ultimate Guide To AttachmentCheck out some other free resources: How To Quit Porn | Anger Meditation | How To Lead In Your RelationshipBuild brotherhood with a powerful group of like-minded men from around the world. Check out The Alliance. Enjoy the podcast? Leave a review on Apple Podcasts, Stitcher, or Podchaser. It helps us get into the ears of new listeners, expand the ManTalks Community, and help others find the tools and training they're looking for. And don't forget to subscribe on Apple Podcasts | Google Podcasts | SpotifyFor more, visit us at ManTalks.com | Facebook | Instagram

Der Pudel und der Kern - Philosophie to go
#190 Langeweile. Unangenehm, aber aufschlussreich. Interview mit der Autorin und Pop-Soziologin Dr. Silke Ohlmeier.

Der Pudel und der Kern - Philosophie to go

Play Episode Listen Later Feb 3, 2026 48:00


Langeweile gilt oft als belangloses Gefühl oder als persönliches Versagen. Doch was, wenn sie ein ernstzunehmendes Signal ist? In dieser Pudelkern-Folge sprechen Albert und Jan mit der Soziologin und Langeweile-Forscherin Dr. Silke Ohlmeier über ein Gefühl, das unangenehm ist und gerade deshalb viel über unser Leben verrät. Silke erklärt, warum Langeweile nicht einfach „nichts zu tun haben“ bedeutet, sondern entsteht, wenn wir tätig sein wollen, es aber nicht können: wenn Sinn, Selbstwirksamkeit und innere Stimmigkeit fehlen. Im Gespräch geht es um situative und chronische Langeweile, um ihre psychologischen und gesellschaftlichen Ursachen und um die Frage, warum Langeweile ungleich verteilt ist. Die Philosophie liefert dabei Tiefenschärfe: von der existenziellen Leere bei Kierkegaard und Heidegger bis zur stoischen Kunst, Unvermeidliches auszuhalten. Eine Folge über Sinnverlust und Sinnsuche, über Muße und Überforderung und darüber, warum Langeweile kein Makel ist, sondern ein Hinweis darauf, dass etwas Wesentliches fehlt.

Huberman Lab
How Dopamine & Serotonin Shape Decisions, Motivation & Learning | Dr. Read Montague

Huberman Lab

Play Episode Listen Later Feb 2, 2026 161:24


Dr. Read Montague, PhD, is a professor and director of the Center for Human Neuroscience Research at Virginia Tech and an expert in how dopamine and serotonin shape human learning, motivation and decision-making. We discuss how they impact focused effort in the context of short- and long-term goals of all kinds. Also, how SSRIs and low-effort, high-engagement activities reduce the rewarding properties of dopamine, and how AI algorithms are revolutionizing understanding of the brain. Episode show notes are available at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman David: https://davidprotein.com/huberman Joovv: https://joovv.com/huberman Function: https://functionhealth.com/huberman LMNT: https://drinklmnt.com/huberman Timestamps (00:00:00) Read Montague (00:02:54) Dopamine, Motivation & Learning (00:08:49) Reward Prediction Error, Expectations (00:12:24) Sponsors: David & Joovv (00:14:54) Foraging, Dating, Expectations vs Outcomes; AI (00:23:36) Dopamine, Expectation, Motivation; Forward Drive; Dopamine "Hits" (00:29:58) Baseline Dopamine & Fluctuations; Parkinson's Disease (00:34:36) Movement, Urgency; ADHD, Bee's Dance, Explorer vs Focus Mode (00:42:29) Sponsor: AG1 (00:43:40) Social Media, ADHD; Explorers vs Task-Based, Combat (00:50:54) Effort, Learning; Social Media & Phones, Resisting Behaviors (01:01:36) Serotonin & Dopamine, Opponency, SSRIs (01:11:21) Hunger, Dopamine; Negative Feedback, Learning, Trauma; Torture (01:18:34) Drugs of Abuse & High Dopamine (01:19:48) Sponsor: Function (01:21:35) Trauma & Dopamine Adaptation (01:27:34) SSRIs, Dopamine, Positive Experiences (01:29:50) Deep Brain Stimulation; Measuring Dopamine & Serotonin in Humans (01:36:16) Sleep; Divorce; Science is a Contact Sport (01:45:14) Long-Term Motivation, Learning How to Fail, Tool: Kids & Sports (01:54:14) Sponsor: LMNT (01:55:34) Meditation, Breathing, Learning; Dopamine as a Currency (02:04:38) Function of Sleep, Motivation; Time Perception & Dopamine, Tracking Time (02:13:18) LLMs, AI, Uses & Problem Solving (02:18:33) Future Projects, Commercial Brain-Machine Interfaces; Concentration (02:25:57) Dopamine "Hits"?; Depression & Schizophrenia; Quitting (02:30:17) Dopamine & Serotonin Misunderstandings; Internal Satisfaction; Motivation (02:35:58) Serotonin Syndrome; Acknowledgements (02:38:31) Zero-Cost Support, YouTube, Spotify & Apple Follow, Reviews & Feedback, Sponsors, Protocols Book, Social Media, Neural Network Newsletter Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices

Health Nerds
Wie Nahrung Gene an- und ausschaltet: SAMe – epigenetische Ernährung (Deep Dive)

Health Nerds

Play Episode Listen Later Feb 2, 2026 16:46 Transcription Available


„Gene sind kein festgeschriebenes Schicksal.“ Ob genetische Informationen aktiv sind oder stumm bleiben, wird nicht allein durch unsere DNA bestimmt. Entscheidend ist auch, wie sie reguliert werden und genau hier kommt die Ernährung ins Spiel. Im diesem HEALTH NERDS Deep Dive widmen sich Podcast-Host Felix Moese und Gesundheitswissenschaftler Matthias Baum einem zentralen Molekül der Epigenetik: S-Adenosylmethionin (SAMe). Es gilt als der wichtigste Methylgruppen-Spender im menschlichen Stoffwechsel und spielt eine Schlüsselrolle bei der Frage, welche Gene abgelesen werden und welche nicht. Im Fokus steht die sogenannte Methylierung. Dieser biochemische Prozess wirkt wie ein Regulationsmechanismus auf unserer DNA: Gene werden nicht einfach „ein- oder ausgeschaltet“, sondern in ihrer Aktivität fein gesteuert. SAMe liefert dafür die notwendigen Methylgruppen und beeinflusst damit, wie intensiv genetische Programme ablaufen - mit weitreichenden Konsequenzen für Zellgesundheit, Entzündungsprozesse und Stoffwechselregulation. Doch SAMe wirkt nicht nur auf epigenetischer Ebene. Es ist beteiligt an der Bildung wichtiger Neurotransmitter wie Serotonin, Dopamin und Noradrenalin, spielt eine Rolle bei der Leberfunktion, der Phospholipidsynthese sowie bei Prozessen der Entgiftung und Zellstabilität. Auch Zusammenhänge mit Stimmung, Stressresilienz, Gelenkgesundheit und chronischen Entzündungen werden wissenschaftlich diskutiert. Die Folge ordnet ein, wie SAMe im Körper entsteht, warum es selbst kaum über die Nahrung aufgenommen wird und welche Rolle seine Vorstufe Methionin sowie begleitende Mikronährstoffe wie Folat, Vitamin B12, B6 und Cholin spielen. Dabei wird deutlich: Epigenetische Regulation ist kein einzelner Schalter, sondern ein fein abgestimmtes System – Balance ist entscheidend, nicht maximale Aktivierung. Für wen ist dieses Thema relevant? Welche Rolle spielt epigenetische Ernährung im Alter, bei chronischen Entzündungen oder erhöhter Stressbelastung? Und wann kann eine gezielte Supplementierung sinnvoll sein und wann nicht?HEALTH NERDS. Mensch, einfach erklärt. Spare 15% auf Deine erste Bestellung auf https://artgerecht.com mit dem Code: HEALTHNERDS15 (im Warenkorb eingeben) Ein ALL EARS ON YOU Original Podcast.

staYoung - Der Longevity-Podcast
Meistgehört: Hormone & Longevity – wie Hormone gesundes Altern prägen | Prof. Huber & Nina Ruge

staYoung - Der Longevity-Podcast

Play Episode Listen Later Feb 1, 2026 53:31


In dieser Folge spreche ich mit Prof. Johannes Huber, einem der profiliertesten Endokrinologen im deutschsprachigen Raum, über Hormone als zentrale Steuerungsfaktoren des Alterns. Jenseits von Östrogen und Testosteron lenken Wachstumshormon, Melatonin, Insulin, Schilddrüsenhormone und weitere Botenstoffe entscheidend, wie schnell wir altern und wie gesund wir bleiben. Professor Huber erklärt, warum nicht Lebensverlängerung um jeden Preis das Ziel ist, sondern eine möglichst vitale zweite Lebenshälfte. Im Gespräch geht es um aktuelle Forschung, um sinnvolle Prävention und um die Frage, wie wir unseren Hormonhaushalt im Laufe des Lebens besser verstehen und begleiten können. In dieser Folge sprechen wir u.a. über folgende Themen: - Welche Rolle spielen Hormone jenseits von Östrogen und Testosteron beim Altern? - Warum nimmt das Wachstumshormon ab dem 30. Lebensjahr kontinuierlich ab? - Wie beeinflusst Wachstumshormon Muskelmasse, Fettverteilung und Fragilität? - Welche Bedeutung hat Melatonin für Schlaf und mitochondriale Gesundheit? - Warum ist Insulin ein zentraler Faktor des biologischen Alterns? - Ab wann sollte der Insulinstoffwechsel regelmäßig kontrolliert werden? - Welche Rolle spielen Stresshormone wie Cortisol langfristig? - Wie beeinflussen Serotonin und Dopamin unsere Resilienz im Alter? - Was leistet Erythropoetin jenseits der Blutbildung? - Warum ist Selbstwahrnehmung ein wichtiger Teil hormoneller Prävention? Weitere Informationen zu Prof. DDr. Johannes Huber findest du hier: https://www.drhuber.at/⁠ Du interessierst dich für Gesunde Langlebigkeit (Longevity) und möchtest ein Leben lang gesund und fit bleiben, dann folge mir auch auf den sozialen Kanälen bei Instagram, TikTok, Facebook oder YouTube. https://www.instagram.com/nina.ruge.official https://www.tiktok.com/@nina.ruge.official https://www.facebook.com/NinaRugeOffiziell https://www.youtube.com/channel/UCOe2d1hLARB60z2hg039l9g Disclaimer: Ich bin keine Ärztin und meine Inhalte ersetzen keine medizinische Beratung. Bei gesundheitlichen Fragen wende dich bitte an deinen Arzt/deine Ärztin. STY-168

Radically Genuine Podcast
217. The Harms of SSRI's During Pregnancy Debate w/ Dr. Adam Urato and Dr. Robert Chen

Radically Genuine Podcast

Play Episode Listen Later Jan 29, 2026 107:13


Three facts are scientifically undisputed: Serotonin is essential for fetal brain development. SSRIs disrupt the serotonin system. SSRIs freely cross the placenta. So why are pregnant women being told these drugs carry "little or no risk"?In this rare head-to-head debate, Dr. Adam Urato—maternal-fetal medicine specialist and FDA expert panelist—faces off against Dr. Robert Chen, a psychiatry resident willing to do what most of his colleagues won't: step into the arena and defend the establishment position.What unfolds is a striking conversation where both physicians actually agree on more than you'd expect—including that informed consent is failing pregnant women, that the chemical imbalance theory is dead, and that "untreated depression" is a misleading frame designed to sell drugs. The uncomfortable question neither side can fully answer: If SSRIs are correcting depression, why does the research show worse outcomes for women who stay on them?This isn't anti-medication propaganda. It's the conversation your doctor isn't trained to have with you.Listen before you fill that prescription. Visit Center for Integrated Behavioral HealthDr. Roger McFillin / Radically Genuine WebsiteYouTube @RadicallyGenuineDr. Roger McFillin (@DrMcFillin) / XSubstack | Radically Genuine | Dr. Roger McFillinInstagram @radicallygenuineContact Radically GenuineConscious Clinician CollectivePLEASE SUPPORT OUR PARTNERS15% Off Pure Spectrum CBD (Code: RadicallyGenuine)10% off Lovetuner click here

Sparking Wholeness
Episode 325: The Real Causes of Depression: Amino Acids, Nutrient Deficiencies, and the Brain-Body Connection with Dr. James Greenblatt

Sparking Wholeness

Play Episode Listen Later Jan 27, 2026 40:21


What if depression isn't “all in your head," but in your body?
In this powerful conversation, host Erin Kerry is joined by Dr. James Greenblatt, MD—one of the world's leading voices in functional and integrative psychiatry and the pioneer of low-dose nutritional lithium for mental health. For more than 30 years, Dr. Greenblatt has been sounding the alarm that psychiatry can do better. Much better. And the research finally agrees: depression is influenced by nutrient deficiencies, immune activation, gut dysfunction, endocrine imbalance, and the brain's biochemical wiring. This episode unpacks the root causes of depression, why nutritional psychiatry is essential for healing, the truth about serotonin, what clinicians get wrong about deprescribing, and the overlooked nutrients that often make the difference between struggling and thriving. If you've ever felt hopeless, stuck, or confused by your symptoms—or if traditional treatments haven't worked—this episode will help you see your mental health through an entirely new (and hopeful) lens. Key Topics: - Why nutritional psychiatry needs to be integrated into all mental health treatment plans - The role of amino acids as precursors for neurotransmitters - Serotonin and depression: science vs. marketing - What everyone should know about deprescribing antidepressants - How B vitamins impact mood, methylation, and energy production - The mineral deficiencies most commonly seen in depression - The nutritional patterns that support recovery from chronic low mood - Root causes of PMDD and natural ways to reduce symptoms - Why Vitamin D is a pivotal regulator of mood and stress - The surprising role of cholesterol and healthy fats in mental health—and why low cholesterol can increase depression risk - How functional psychiatry gets to the root cause instead of masking symptoms - A preview of Dr. Greenblatt's new book, Finally Hopeful 
Links: Website: jamesgreenblattmd.com Book: Finally Hopeful Instagram: @psychiatryredefined Join Erin's monthly mailing list to get health tips and fresh meal plans and recipes every month: https://mailchi.mp/adde1b3a4af3/monthlysparksignup Order Erin's new book, Live Beyond Your Label, at erinbkerry.com/upcomingbook/

The Dr. Haley Show
139 | Eating Disorders, Ultra-Processed Food & Gut Health: What Actually Heals the Body with Lexi

The Dr. Haley Show

Play Episode Listen Later Jan 27, 2026 35:49


Is ultra-processed food making mental and gut health worse—especially for kids and teens?In this episode of **The Dr. Haley Show**, Dr. Michael Haley sits down with Lexi, a real-food advocate and social media creator whose personal journey through anorexia led her to uncover a powerful truth: healing doesn't come from ultra-processed “nutrition,” but from real food, gut health, and mindset change.This conversation isn't about fad diets, weight loss, vegan vs carnivore, or extreme rules. It's about stepping back and asking bigger questions about **food, mental health, gut health, faith, and long-term healing**—especially for young people.Lexi shares her experience being diagnosed with anorexia at 13, the harmful nutrition advice she was given, how gut health and serotonin affect mental health, and why so many people relapse when recovery focuses on weight instead of healing.Dr. Haley adds perspective for parents, families, and anyone concerned about how modern food systems are impacting physical and mental health—one bite at a time.In this episode:* Why ultra-processed food can make eating disorder recovery harder* How gut health affects serotonin, mood, and mental health* Why “everything in moderation” often fails people who are struggling* What *real food* actually means in simple terms* How to spot fake food at the grocery store* Better energy alternatives to energy drinks* Why kids and teens are especially vulnerable to food misinformation* How faith, purpose, and mindset play a role in healingThe Dr. Haley Show is dedicated to helping you optimize your health by challenging conventional wisdom, exploring root causes, and returning to foundational principles that actually work—nutrition, gut health, lifestyle, and purpose.###

The Well
Why You Can't Just "Quit": Dopamine, Vaping & Altered Brain Chemistry

The Well

Play Episode Listen Later Jan 21, 2026 38:35 Transcription Available


What is the deadliest item in London’s Vagina Museum? Why are drug addiction rates in Australia spiking by over 30% post-pandemic? And if you’ve already had two surgeries for inherited bunions, is “third time’s a charm" actually possible? What makes a substance addictive, and why is it so hard to just "quit"? In this episode, Claire Murphy and Dr. Mariam dive into the complexities of drug addiction in Australia, from the alarming rise of vaping among teens, to the shifting chemistry of the brain. We are joined by Dr. Shalini Arunogiri, an addiction psychiatrist, Associate Professor at Monash University and Clinical Director at Turning Point. She breaks down the "reward" chemicals like dopamine and serotonin that hook us, the reality of relapse, and why alcohol remains the most harmful drug from a population health perspective. Dr. Shalini also addresses the cannabis debate - exploring the link between high-potency use and psychosis - and why the term "addict" is being replaced by more empathetic, health-centered language. But first, we take a field trip to London’s Vagina Museum to look at its deadliest item…We discuss the history of Toxic Shock Syndrome (TSS), the biology of the vaginal wall and why "retained tampon smell" is a more common clinic visit than you’d think. And, in our Quick Consult, Dr. Mariam helps listener Simone navigate the tricky world of "inherited bunions". EPISODE RESOURCES: If this episode has raised concerns for you, or if you are considering your own substance use, the following resources are available for confidential support: Counselling Online: The recommended first port of call for those questioning their drug use or looking for help. It features a Self-Assessment Quiz, a national directory and 24/7 access to online chat or telephone-based support. National Alcohol and Other Drug (AOD) Hotline: For free and confidential advice, call 1800 250 015. SMART Recovery Australia: A network of evidence-based support meetings for people seeking recovery. And if this episode triggered anything for you and you need someone to talk to, please call Lifeline on 13 11 14. GET IN TOUCH Sign up to the Well Newsletter to receive your weekly dose of trusted health expertise without the medical jargon. Ask a question of our experts or share your story, feedback, or dilemma - you can send it anonymously here, email here or leave us a voice note here. Ask The Doc: Ask us a question in The Waiting Room. Follow us on Instagram and Tiktok. Support independent women’s media by becoming a Mamamia subscriber CREDITS Hosts: Claire Murphy and Dr Mariam Guest: Senior Producers: Claire Murphy and Sally Best Audio Producer: Scott Stronach Video Producer: Julian Rosario Social Producer: Elly Moore Mamamia acknowledges the Traditional Owners of the Land we have recorded this podcast on, the Gadigal people of the Eora Nation. We pay our respects to their Elders past and present, and extend that respect to all Aboriginal and Torres Strait Islander cultures.Information discussed in Well. is for education purposes only and is not intended to provide professional medical advice. Listeners should seek their own medical advice, specific to their circumstances, from their treating doctor or health care professional. +++++++++++++++++++++++++++++++++++++++++++++++++++++++++++Support the show: https://www.mamamia.com.au/mplus/See omnystudio.com/listener for privacy information.

The Neuro Experience
The Fasting Expert: Why Women Should NEVER Fast at this time | Dr. Mindy Pelz

The Neuro Experience

Play Episode Listen Later Jan 20, 2026 70:06


It's a controversial topic, fasting, especially for women. Dr. Mindy Pelz was teaching women to fast primarily because they wanted to lose weight, but what she was witnessing was women saying things like, "I lost weight, but my hair's falling out. I don't have a period anymore. I sat down with Dr. Mindy Pelz, New York Times bestselling author of Age Like a Girl, hormone expert, and the voice redefining fasting for women - because doing it wrong can wreck your health. We explore why fasting affects women differently, how ketones can restore brain function during menopause, and why understanding your hormonal cycle is critical for metabolic health, cognitive performance, and longevity. Reduce your risk of Alzheimer's with my science-backed protocol for women 30+: https://go.neuroathletics.com.au/youtube-sales-page Subscribe to The Neuro Experience for evidence-based conversations at the intersection of brain science, longevity, and performance. _____ TOPICS DISCUSSED 00:00 Intro 01:50 What put Dr. Mindy Pelz on the map 03:14 The truth about fasting vs intermittent fasting 05:13 How the brain uses glucose vs ketones 07:25 Why the brain "eats itself" during menopause 10:14 What is mitophagy and cellular autophagy 13:11 Why autophagy is the body's repair system 15:24 The 12-hour vs 17-hour vs 72-hour fast 17:23 Why women's cycles are disrupted by fasting 19:59 The fasting cycle for women 21:05 Lactate as a fuel source for the brain 23:01 Hemoglobin A1C and insulin resistance 27:36 Understanding CGM data correctly 30:13 Where women should start at 48 32:01 HRT: personal decision or necessity? 34:15 The nervous system shift during perimenopause 38:48 The grandmother hypothesis and evolutionary sensitivity 41:09 The "menopause divorce" phenomenon 44:18 Dementia, Alzheimer's, and women46:17 Dopamine, novelty, and neuroplasticity47:23 Cold water immersion and trauma rewiring51:19 Cold water and cortisol for women53:51 Exercise, BDNF, and brain health55:21 Serotonin, light exposure, and sleep58:00 Glycine, bone broth, and longevity01:02:26 Preparing for perimenopause and menopause 01:04:24 Acetylcholine, storytelling, and memory 01:08:38 Why eggs and cholesterol matter for the brain _______ A huge thank you to my sponsors for supporting this episode. Check them out and enjoy exclusive discounts: Ketone-IQ: Mental clarity that lasts - without the crash. Visit https://ketone.com/NEURO for 30% OFF your subscription order - PLUS receive a free gift with your second shipment or find Ketone-IQ at Target stores nationwide and get your first shot free! IQBAR: The New Year gives us all a chance to reset. Maximize your brain and body's potential with IQBAR's protein bars, hydration mixes, and mushroom coffees. Text NEURO to 64000 to get 20% off all IQBAR products, plus FREE shipping. Caraway: Visit Carawayhome.com/neuro10 or use code neuro10 at checkout to take an additional 10% off your next purchase. Caraway. Non-Toxic cookware made modern. Cure Hydration: For The Neuro Experience listeners, you can get 20% off your first order at curehydration.com/NEURO with code NEURO. Cure is FSA/HSA approved, so you can use your FSA or HSA funds to stay hydrated the smart way. Jones Road Beauty: Use code NEURO at jonesroadbeauty.com to get a Free Cool Gloss with your first purchase! _______ I'm Louisa Nicola - clinical neurophysiologist - Alzheimer's prevention specialist - founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention. If you're committed to optimizing your brain- reducing Alzheimer's risk - and staying mentally sharp for life, you're in the right place. Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0 Instagram: https://www.instagram.com/louisanicola_/ Twitter : https://twitter.com/louisanicola_ Learn more about your ad choices. Visit megaphone.fm/adchoices

HALO Talks
Episode #584: From Corporate Success to Franchise Operator-Chris Rotondi's Journey with Serotonin Centers

HALO Talks

Play Episode Listen Later Jan 20, 2026 26:40


On this episode of HALO Talks, host Pete Moore sits down with Chris Rotondi, franchisee of a Serotonin Center in Greenwich, Connecticut. From his early days as the 13th employee at Shift4 to his foray into the HALO (Health, Active Lifestyle, Outdoor) space, Chris talks about his entrepreneurial path and passion for biohacking, longevity, and helping others transform their lives. Listen now as Pete and Chris discuss the hard truths behind starting and scaling a HALO business, the importance of authentic local marketing, and the unique advantages (and sometimes challenges!) of joining a strong franchise network. Whether you're interested in the business side of wellness, new trends in anti-aging, or just enjoy hearing candid stories from the front lines of entrepreneurship, this episode delivers plenty of insights and takeaways. (And if you missed it, we interviewed Seratonin Center CEO Eric Casaburi a while back. Link down below.)  On expanding within a franchise, Rotondi states, "After your first store it gets a lot easier to take where you are in that first location, and start the second one from that same level, rather than going back and having to relearn all those rookie mistakes that maybe you made when you first opened." Key themes discussed Chris's inspiration to open a Serotonin Center. The importance of word-of-mouth and community marketing. Challenges and rewards of operating a franchise. The evolving mainstream acceptance of biohacking and longevity practices. Collaborations and partnerships with local businesses for mutual growth. Scaling, staffing, and operational complexities in health franchises. A Few Key Takeaways:  1.Entrepreneurial Path & Inspiration: Rotondi shared how his extensive experience at Shift4, where he was surrounded by entrepreneurs and watched a company scale from startup to IPO, inspired him to eventually strike out on his own. This not only shaped his mindset but also gave him the confidence and motivation to take the leap into business ownership. 2. Choosing Serotonin Centers Was a Passion Play: Rather than conducting an exhaustive analysis of possible business options, Chris says that he was immediately drawn to Serotonin and felt a strong alignment with the concept. He dabbled in real estate but realized he needed a business that delivered a tangible positive impact—and found that in the HALO space. 3. Transformative Results Make the Business Rewarding: The most fulfilling aspect of running the center is seeing noticeable transformations in clients—whether it's 35-40 pounds of weight loss or improved health outcomes. These stories not only validate the mission but also create infectious momentum through word of mouth. 4. Franchising as a Strategic Advantage: Rotondi also emphasizes the value of being part of a franchise system, especially in a highly regulated, evolving industry like health and longevity. The franchisor provides critical infrastructure, best practices, and ongoing support, allowing franchisees to scale faster and avoid common pitfalls that solo operators might typically face. 5. Local Networking & Authentic Marketing Are Key: For growth, Chris focuses on the importance of networking and building authentic relationships in his local market (Greenwich, CT). Word of mouth remains king, and collaborations with other health and wellness businesses (like co-branded menu items with nearby cafés) drive new client acquisition and community engagement. Resources:  Chris Rotondi: https://www.linkedin.com/in/chris-rotondi  Seratonin Centers: https://www.serotonincenters.com  Eric Casaburi Seratonin CEO: https://www.halotalks.com/episode-368-eric-casaburi-serotonin-anti-aging-centers  Integrity Square: https://www.integritysq.com Prospect Wizard: https://www.theprospectwizard.com Promotion Vault: https://www.promotionvault.com HigherDose: https://www.higherdose.com

Teach Me How To Adult
ICYMI: The Science of Seasonal Affective Disorder & Insomnia: Biohacking SAD With Light & Serotonin, with Chemical Engineer Chloe Deutscher

Teach Me How To Adult

Play Episode Listen Later Jan 19, 2026 8:36


Welcome to today's ICYMI, where we kick off the week with a quick game-changing tip from past episodes that you might have missed. If the January blues have hit and Seasonal Affective Disorder has you crashing out, we've got you. Winter can leave us feeling exhausted, sad, unmotivated, and plagued by insomnia, so we're throwing it back to biohacking expert Chloe Deutscher to break down what actually helps, from light therapy and SAD lamps to sleep regulation, overcoming insomnia, and supplements that naturally support mood + serotonin.Chloe is a chemical engineer who has dedicated her career to the intersection of science, consciousness, and mental health. She's the co-founder and the CEO of Liquid Culture, a biotech company focused on novel fungi manufacturing and developing innovative products for optimal wellbeing. She shares her actionable tips, knowledge, and experience in the fields of biohacking, mental health, and psychedelics on her popular TikTok account, where she empowers people to overcome mental health challenges like ADHD, anxiety, and depression. Listen to our full episode here.Tune in every Monday for an expert dose of life advice in under 10 minutes.For advertising and sponsorship inquiries, please contact Frequency Podcast Network. Sign up for our monthly adulting newsletter:teachmehowtoadult.ca/newsletter Follow us on the ‘gram:@teachmehowtoadultmedia@gillian.bernerFollow on TikTok: @teachmehowtoadultSubscribe on YouTube

Ageless by Rescu
Unlocking the Gut–Brain Connection with Srinivas Kamath

Ageless by Rescu

Play Episode Listen Later Jan 19, 2026 47:23


This conversation explores the complex and deeply human relationship between gut health and mental wellbeing. Srinivas Kamath shares insights from his research into the gut–brain axis, unpacking how hormones, stress, medication and diet intersect at the microbiome level. We discuss the limitations of current mental health treatments, the growing promise of prebiotics, and why personalised medicine may be the future of emotional and cognitive care. The episode also looks ahead to emerging research in longevity, GLP-1 therapies and the role of the gut in neurodegenerative disease, offering a grounded yet hopeful view of where this science is heading. Key Takeaways The gut and brain operate in constant two-way communication, influencing mood, cognition and emotional regulation. Chronic stress and elevated cortisol can compromise the gut lining, contributing to inflammation and so-called leaky gut. Female hormones shape the microbiome across the lifespan, and gut health in turn affects hormonal balance. Understanding an individual’s microbiome opens the door to truly personalised approaches to mental and emotional health. Many psychiatric medications alter the gut microbiome, which may explain common side effects and variable outcomes. Prebiotics play a foundational role in supporting a resilient and diverse microbiome.For most people, prebiotics are more effective and sustainable than probiotic supplementation alone. GLP-1 is central to appetite regulation, gut signalling and broader metabolic and mental health pathways. The vagus nerve acts as a key communication highway between the gut and the brain.Gut microbiome research is rapidly evolving, with more questions than definitive answers at this stage. Episode Chapters 00:00 Introduction and the gut–brain connection02:50 How hormones influence gut health05:34 Precision medicine and mental health outcomes08:30 Fecal microbiota transplants explained11:25 Why prebiotics matter14:02 Probiotics versus prebiotics16:59 Everyday ways to support gut health19:46 Cortisol, stress and GLP-122:15 Revisiting the gut–brain axis23:53 Serotonin, dopamine and the gut26:21 Emotional blunting and GLP-1 medications29:18 Gaps in medical education30:36 Drug development timelines33:10 Funding challenges in microbiome research35:18 The role of AI in gut health science37:02 Why gut health underpins overall wellbeing39:37 Integrating traditional and emerging approaches41:47 The microbiome and longevity42:38 Gut health and neurodegenerative disease43:37 How to begin a prebiotic-first approach Watch the full episode here: https://youtu.be/PYgWVYHdI_ISee omnystudio.com/listener for privacy information.

From the Spectrum: Finding Superpowers with Autism
White Board Series (Audio Version): Hypothyroidism, Serotonin & T3: Hidden Biomarkers in Autism & Parkinson's

From the Spectrum: Finding Superpowers with Autism

Play Episode Listen Later Jan 18, 2026 29:48 Transcription Available


Video: https://www.youtube.com/watch?v=A6ymQgVLC5cAutism & Parkinson's https://youtu.be/1E53ZYehUCU?si=69pKeFSKi07GGsATHypothyroid Biomarker https://youtu.be/X6CxX9kA6b0?si=Bkr8ZKooNdie-N6IDr. Kristen Lyall, ScD https://youtu.be/cjBR8m82KZQ?si=C-Tclr25oBbid7qGNicole Rincon & links to her other episodes in notes https://youtu.be/jRd7rE38W90?si=i8CvVutA4a1K9NzeDaylight Computer Company, use "autism" for $50 off at https://buy.daylightcomputer.com/autismChroma Light Devices, use "autism" for 10% discount at https://getchroma.co/?ref=autismFig Tree Christian Golf Apparel & Accessories, use "autism" for 10% discount at https://figtreegolf.com/?ref=autismCognity AI for Autistic Social Skills, use "autism" for 10% discount at https://thecognity.com00:00 Serotonin Recap: thalamocortical connections (esp. S1 somatosensory)02:41 Aromatic Amino Acids & UV-sensitive aromatic benzene rings04:56 Personal Sunlight Reversal Host reversed Hashimoto's (2005–2024) via increased sunlight07:58 Cell-Level Roles Serotonin drives neurogenesis, migration, dendrites/spines; T3 matures organelles, myelination & cellular energy11:00 Maternal Thyroid Dependency Fetus relies on maternal T3/T4 until ~weeks 16–20; hypothyroidism as easy, modifiable biomarker for autism/Parkinson's13:07 Substantia Nigra & Basal Ganglia Neuromelanin/dopamine loss in substantia nigra links autism & Parkinson's; disrupts basal ganglia go/no-go orchestration15:44 Mitochondria & Melanin Energy Cytochrome c oxidase produces H2O in ETC; melanin + water coupling provides power 18:00 Hypothyroidism Biomarker Call Undisputed, simple-to-check risk factor; urgent prenatal thyroid screening & sunlight exposure needed20:36 Modern Environment Impact Blue light/low sunlight blocks synthesis; upstream fixes (reflexes, thyroid checks, sunlight) offer prevention/recovery potential22:15 Serotonin & T3 Synergy Serotonin architects connections; T3 engineers cell/organelle maturity & myelination; combined deficits cascade into autism/Parkinson's24:00 Substantia Nigra Detail Loss of neuromelanin/dopamine in substantia nigra (mesencephalon) impairs basal ganglia; ties to movement disorders in both conditions25:44 Mitochondria Water Production Cytochrome c oxidase (complex IV) generates H2O; melanin & water 27:58 Final Synthesis & Implications Serotonin + T3 critical for cell development/myelination; maternal hypothyroidism disrupts both autism/Parkinson's riskX: https://x.com/rps47586YT: https://www.youtube.com/channel/UCGxEzLKXkjppo3nqmpXpzuAemail: info.fromthespectrum@gmail.com

The Other Side of Midnight with Frank Morano
Hour 4: Soul vs. Serotonin | 01-16-26

The Other Side of Midnight with Frank Morano

Play Episode Listen Later Jan 16, 2026 52:10


Join Lionel on The Other Side of Midnight as he delves into the "psychiatric underbelly" of society, questioning whether we have criminalized mental illness or simply misunderstood it. Listen in as Lionel spars with callers about the fine line between spiritual possession and schizophrenia, debating whether our personalities come from the soul or just a slide on a neurochemical mixing board. The conversation takes a turn into the digital afterlife, exploring the creepiness of active Facebook pages for the deceased and receiving voicemails from beyond the grave. Plus, Lionel dissects the "instinct for attribution" that created religion, explains why praying for a baseball team is blasphemy, and offers unsentimental dating advice: forget romance—marriage is a business, so run a credit report before you say "I do". Learn more about your ad choices. Visit megaphone.fm/adchoices

From the Spectrum: Finding Superpowers with Autism
White Board Series (Audio Version): Serotonin's Role in Development for Sensory Maps

From the Spectrum: Finding Superpowers with Autism

Play Episode Listen Later Jan 15, 2026 37:14 Transcription Available


In this whiteboard-style episode, we delve into serotonin's pivotal yet underrated role in prenatal brain development and autism, tracing its origins from maternal tryptophan (primarily gut-derived in the first trimester) through fetal production shifts across trimesters. Derived from an aromatic amino acid, serotonin drives neurogenesis, migration, and critical wiring of thalamo-cortical connections—especially for the somatosensory cortex (S1)—shaping mini-columns and sensory maps. We contrast diffusion (chaotic, unpruned connections leading to overload) with refinement (clear boundaries via proper pruning), explaining how imbalances foster sensory chaos, poor signal-to-noise discrimination, and inward bias in the autistic phenotype, while setting the stage for comparisons with T3 thyroid hormone's developmental influence.Daylight Computer Company, use "autism" for $50 off at https://buy.daylightcomputer.com/autismChroma Light Devices, use "autism" for 10% discount at https://getchroma.co/?ref=autismFig Tree Christian Golf Apparel & Accessories, use "autism" for 10% discount at https://figtreegolf.com/?ref=autismCognity AI for Autistic Social Skills, use "autism" for 10% discount at https://thecognity.com00:00 Serotonin role in pregnancy/development; beyond mood, neurogenesis/synaptogenesis from neuralation, Tryptophan Basics From aromatic amino acid tryptophan (one codon); distinct TPH1 (peripheral/gut) vs TPH2 (brain) pathways02:41 Neuralation & Trimesters First trimester: all maternal serotonin (95% gut); regulates cell proliferation; neuroepithelial cells form brain divisions05:46 Mesencephalon Details Doesn't subdivide; key roles: sensory integration, motor, external attention orientation—highly relevant to autism07:58 Serotonin Sources Shift Second trimester: fetus starts own production; maternal still significant; builds placenta/umbilical physiology11:12 Thalamus & Sensory Maps Serotonin wires thalamus to cortex (esp. S1 somatosensory > V1/A1); structures mini-columns for sensory processing15:38 Mini-Columns Structure 6 cortical layers; thalamus inputs to layer 4; layers 2/3 for experience/intelligence; autistic: narrower neuropil (~40-60μm)20:51 Diffusion vs Refinement Serotonin prunes connections; abnormal levels → diffusion (weak, competing links, chaos) vs refinement (clear edges)28:42 Signal-to-Noise Issues Diffusion causes poor boundaries, overload; inward bias ("autism" meaning self) as adaptation to external chaos35:59 Critical Period Implications Prenatal setup affects salience network; early detection/intervention potential; serotonin vs T3 comparison upcoming.X: https://x.com/rps47586YT: https://www.youtube.com/channel/UCGxEzLKXkjppo3nqmpXpzuAemail: info.fromthespectrum@gmail.com

Ever Forward Radio with Chase Chewning
EFR 919: The Gut–Brain–Immune Connection: The New Science of Inflammation and Why You Can't Heal the Gut Without Healing the Mind with Will Bulsiewicz

Ever Forward Radio with Chase Chewning

Play Episode Listen Later Jan 12, 2026 87:34


This episode is brought to you by Joi & Blokes, Fatty15, and Strong Coffee Company. In this powerful conversation, Dr. Will Bulsiewicz, MD joins Ever Forward Radio to explore why true healing goes far beyond food, supplements, and exercise—and into the nervous system, emotional health, and human connection. Drawing from his new book Plant Powered Plus, Will explains how inflammation is driven by an inseparable triad of gut microbiome imbalance, immune dysfunction, and a compromised gut barrier, while also revealing how chronic stress, unresolved trauma, loneliness, and circadian disruption can prevent the body from ever feeling safe enough to heal. This episode clearly explains the gut–brain–immune axis, the role of parasympathetic "safety" states, why PTSD and trauma leave measurable signatures in the gut, and how practices like sunlight exposure, breathwork, meaningful relationships, and spiritual purpose are not "woo"—but biology.  Follow Will @theguthealthmd Follow Chase @chase_chewning ----- 00:00 – Introduction: Why You're Not Healing (It's Not Just Food) 01:30 – Inflammation, Strength & the Core Thesis of Plant Powered Plus 02:25 – 70% of the Immune System Lives in the Gut 03:40 – The Inflammation Trifecta: Dysbiosis, Gut Barrier & Immunity 05:10 – How Fast the Gut Microbiome and Gut Lining Can Heal 06:00 – 450,000 New Gut Cells Every Second 09:00 – Why the Body Wants to Heal (If We Let It) 10:00 – Morning Sunlight, Circadian Rhythm & Energy 11:30 – Gut Microbes Follow a 24-Hour Schedule 12:45 – Why the Immune System Is Active at Night 14:00 – Serotonin, Melatonin & Gut Repair 16:00 – Cortisol: When Stress Helps vs. Harms 18:30 – The Sympathetic Nervous System & "Berserker Mode 21:45 – How Chronic Stress Damages the Gut Barrier 24:00 – Trauma, PTSD & Inflammatory Disease 26:00 – Why You Can't Out-Diet Trauma 29:00 – Science, Pattern Recognition & the Mind–Body Connection 32:00 – Parasympathetic Healing: Safety, Rest & Digestion 34:00 – Breathwork, Meditation & Nervous System Regulation 36:00 – Human Connection as Medicine 38:30 – Loneliness, Mortality & Modern Society 43:00 – Why Meaningful Relationships Are Essential for Health 46:00 – Can You Be Healthy Without Deep Connection? 49:00 – Measuring Stress: HRV, Wearables & Inflammation 55:30 – Trauma, PTSD & the Gut Microbiome 58:00 – Healing Trauma and Healing the Gut Together 1:03:30 – Dr. Bulsiewicz's Personal Healing Story 1:09:30 – Reconciliation, Grief & Spiritual Healing 1:18:00 – Purpose, Faith & the Limits of Science 1:22:00 – Ever Forward ----- Episode resources: Get 50% off any diagnostic labs with code CHASE at https://www.JoiAndBlokes.com/chase Get an additional 15% off the 90-day starter kit of C15:0 essential fatty acids https://www.Fatty15.com/everforward Save 15% on organic coffee and lattes with code CHASE at https://www.StrongCoffeeCompany.com Watch and subscribe on YouTube Get Will's new book, Plant Powered PLUS Learn more at TheGutHealthMD.com

Sahil Adeem Podcast
Qur'an, Brain Chemistry & Pakistan's Crisis | Sahil Adeem Podcast

Sahil Adeem Podcast

Play Episode Listen Later Dec 31, 2025 177:13


(0:00) Intro(3:36) “Today is your day with the Qur'an” — why he came to medical students(4:28) Who came by choice, who was dragged? An honest audience check(6:23) “Don't listen to what Pakistanis say” — social psychology 101(8:02) Warning: a high-potency “chemistry session” with side effects(9:18) Serotonin 101 — mother's tears and childhood emotional locking(13:01) Money, parents' reactions, and how success gets hard-wired(19:16) When you jump into the Qur'an, it lights up the whole country(20:42) Parliament, VIP protocols, and the side effects of leaving the Qur'an(24:30) Serotonin, titles, and why “Doctor” feels so powerful(32:02) Pharma, protocols, and SSRIs — who really controls thresholds?(40:00) Makeup, niqab, and female serotonin — confidence vs costume(48:05) Endowment effect — flags, clubs, and being “extra Pakistani”(53:05) Bharat Mata, Greater Israel, and why Islam isn't geographically locked(54:05) “You are more Pakistani and less Muslim” — identity breakdown(1:03:20) Pakistan, Pakistan, Pakistan — stuck in the national loop(1:10:04) Mission mode — Sahil as a “missionary” and why he looks for performers(1:18:21) Qur'an, stars, and science — why Muslims should lead global research(1:26:16) Doctors, research, and turning papers into real-world impact(1:32:20) IMS (Islamic Messaging System) platform and next steps for doctors Hosted on Acast. See acast.com/privacy for more information.

The Other Side of Midnight with Frank Morano
Hour 3: Serotonin Sliders | 12-30-25

The Other Side of Midnight with Frank Morano

Play Episode Listen Later Dec 30, 2025 52:38


Dive into the "organized carelessness" of late-night conversation with Lionel on The Other Side of Midnight. Lionel navigates the vectors of the human condition, shifting from the clinical realities of depression and seasonal melancholia to the gritty, legendary history of Hell's Kitchen. Whether unpacking the comedic genius of Groucho Marx, debating the dangers of AI for children, or offering a compassionate ear to callers facing loss and disability, Lionel explores the software of the human brain with wit, empathy, and intellectual grit. Learn more about your ad choices. Visit megaphone.fm/adchoices

ADHD Big Brother
225 - Tension and the Desire for a System

ADHD Big Brother

Play Episode Listen Later Dec 29, 2025 16:04


Crappy tasks never feel right in the moment. There's always tension. I have some thoughts on that and a challenge for you! Mentioned in the podcast:My new webpage for the community! Check it out hereDr. Shane Calhoun on ADHDBBDr. Shane's Routines WorkshopEpisode 168 - Dr. Shane Talks ADHD and AddictionEpisode 147 - Dr. Shane Talks Dopamine, Serotonin, ADHD and DepressionGot 5 minutes? Help me learn how to best support you by taking the ADHDBB Survey. Here's the link to my short survey. Thanks!

The Better Life with Dr. Pinkston Podcast
Unmasking Food Triggers: The Power of the Elimination Diet

The Better Life with Dr. Pinkston Podcast

Play Episode Listen Later Dec 27, 2025 57:26


Is what you’re eating causing your pain, fatigue, or stubborn weight gain? Join Dr. Pinkston and nutritionist Laura LaValle as they dive deep into the Elimination Diet—the gold standard for identifying hidden food sensitivities. In this episode, Dr. Pinkston explores why modern life has triggered a surge in "leaky gut" and how removing common culprits like gluten, dairy, and soy can resolve everything from chronic migraines to seasonal allergies. Learn the exact protocol to reset your system, boost your metabolism, and finally understand your body’s unique needs.See omnystudio.com/listener for privacy information.

Mind & Matter
Stress & Psilocybin: Effects on Maternal Care & Offspring Development | Danielle Stolzenberg | 270

Mind & Matter

Play Episode Listen Later Dec 26, 2025 111:57


Send us a textNeurobiology of maternal care in mammals: hormonal influences, stress effects & a study on psilocybin's unexpected effects during the postpartum period.Topics Discussed:Maternal care behavior in rodents: Nursing, pup retrieval, grooming, and nest-building, essential for altricial pups' survival; conserved across mammals but varies by species.Hormonal changes in pregnancy: Estradiol and progesterone surge then drop at birth, crossing the blood-brain barrier to enable infant attraction and care via gene expression and neuroplasticity.Brain circuitry for parenting: Medial preoptic area acts as a central hub, coordinating motivation and sensory inputs; present in both sexes but activated differently by hormones and experience.Stress impacts on mothers: Social stressors like male intruders dysregulate care, leading to frantic behaviors and avoidance; models human psychosocial stress linked to postpartum mood disorders.Sex differences in pup care: Mothers groom male pups more, influencing sexual behaviors, which effects future behavior.Psilocybin in postpartum mice: Single dose increased anxiety in mothers, showed no antidepressant effects, and transferred via milk, causing long-term anhedonia and impairments in offspring as adults.Serotonin system development: Early exposure to serotonergic drugs like psilocybin or SSRIs alters lifelong behavior, highlighting sensitive periods in brain reorganization.Practical Takeaways:Reduce postpartum stress through social support to enhance maternal bonding and minimize mood disorder risks.Approach psychedelics cautiously during postpartum due to potential anxiety increases and offspring effects via milk.Recognize hormonal shifts heighten sensitivity to infant cues, aiding natural caregiving instincts.Monitor environmental factors like food availability or threats that could disrupt parental behaviors in high-stress scenarios.About the guest: Danielle Stolzenberg, PhD is an associate professor of psychology at the University of California, Davis, where her lab studies the neurobiology of maternal care.Reference Paper:Study: Psilocybin during the postpartum period induces long-lasting adverse effects in both mothers and offspringRelated Episode:Support the showAffiliates: Lumen device to optimize your metabolism for weight loss or athletic performance. MINDMATTER gets you 15% off. AquaTru: Water filtration devices that remove microplastics, metals, bacteria, and more from your drinking water. Through link, $100 off AquaTru Carafe, Classic & Under Sink Units; $300 off Freestanding models. Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they're hiding, with this easy-to-use mobile app. KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime) For all the ways you can support my efforts

Vitality Radio Podcast with Jared St. Clair
#598: VR Vintage: Your Parasite Cleansing User's Guide

Vitality Radio Podcast with Jared St. Clair

Play Episode Listen Later Dec 24, 2025 74:43


This episode originally aired as #432 on 5/22/24 and we are bringing it to you again! Parasite cleansing has become a hot topic in the natural health world, but it can feel a little overwhelming. Are you confused about where to start or how to do a cleanse yourself? On this episode of Vitality Radio, Jared demystifies the process by sharing his experience along with his wife's, and a thorough breakdown of the entire process, the products, and what to expect. You'll learn a couple of ways to approach parasite cleansing and which one might be right for you or your family, including kids.  If you never thought about parasites being a problem in America, think again! For a deeper understanding of why parasites are indeed a bigger problem than is understood by most, be sure to listen to Jared's interviews with Dr. Todd Watts and Dr. Jay Davidson - the founders of CellCore.Products:CellCore Para KitVitality Nutrition Parasite CleanseVital 5 Precision Probiotic Vital SporesMagnesium BisglycinateCellCore Bowel MoverLife Seasons Regulari-TRedmond RelyteTrace Minerals Endure Drops***Inquire for capsule-free protocol Additional Information:For information on coaching options and personalized support, please email jessica@vitalitynutrition.comVitality Wellness Community Detox & Support GroupVitality Radio Podcast Listener Community#359: Comprehensive Detoxification of Parasites, Lyme, and Other Toxins With Dr. Todd Watts of CellCore Biosciences#431: Are Parasites Part of Your Health Concerns? With Dr. Jay Davidson#385: Rebalancing and Healing the Body Through Functional Medicine Detoxification With Dr. Stephen Cabral#258: Your Magnesium User's Guide***Be sure to check out all of the Emotional Vitality Episodes, including Jen's Story mentioned in this showVisit the podcast website here: VitalityRadio.comYou can follow @vitalityradio and @vitalitynutritionbountiful on Instagram, or Vitality Radio and Vitality Nutrition on Facebook. Join us also in the Vitality Radio Podcast Listener Community on Facebook. Shop the products that Jared mentions at vitalitynutrition.com. Let us know your thoughts about this episode using the hashtag #vitalityradio and please rate and review us on Apple Podcasts. Thank you!Please also join us on the Dearly Discarded Podcast with Jared St. Clair.Just a reminder that this podcast is for educational purposes only. The FDA has not evaluated the podcast. The information is not intended to diagnose, treat, cure, or prevent any disease. The advice given is not intended to replace the advice of your medical professional.

The High Guide
The 5-MeO-DMT Experience: Nervous System Surrender, Safety, and the God Molecule

The High Guide

Play Episode Listen Later Dec 23, 2025 25:54


115. 5-MeO-DMT Experience ExplainedA grounded conversation on the 5-MeO-DMT experience—how it affects the nervous system, how it differs from DMT, and why safety and integration matter.Episode SummaryWhat is 5-MeO-DMT, and why do people describe it so differently from other psychedelics?In this episode, April Pride sits down with licensed clinicians and facilitators Roger and Dustin to explore the 5-MeO-DMT experience through both lived experience and emerging neuroscience. Often referred to as the God molecule psychedelic, 5-MeO-DMT is widely described as a non-visual psychedelic experience—one that quiets the nervous system rather than amplifying imagery, stories, or symbols.Together, they break down 5-MeO-DMT vs DMT, explain how this compound interacts with serotonin receptors in the brain, and discuss why many people report profound ego dissolution, nervous system regulation, and long-term shifts in how they experience safety and connection.This episode also centers women and psychedelics, examining why women—particularly those who have spent years in control, caretaking, or emotional labor—may feel especially drawn to this form of surrender-based medicine.If you're seeking grounded insight into psychedelic harm reduction, integration after 5-MeO-DMT, and what makes this medicine fundamentally different from other psychedelic experiences, this conversation is an essential listen.

Metabolic Mind
Rethinking Serotonin And Depression: What SSRIs Really Do & What May Work Better

Metabolic Mind

Play Episode Listen Later Dec 22, 2025 39:08


Do SSRIs help your brain?SSRI medications are among the most widely prescribed antidepressants, but what if we've misunderstood how they work? In this interview, Dr. Bret Scher sits down with biochemist and nutrition scientist Dr. Chris Masterjohn to explore a deeper, more systemic view of mental health and how we treat it.Dr. Masterjohn reveals why serotonin isn't just a “mood booster,” how SSRIs may be disrupting mitochondrial function, and why focusing on lifestyle strategies that support brain energy metabolism could unlock new paths for treating depression.

The Dairy Podcast Show
Dr. Laura Hernandez: Calcium Balance in Dairy Cows | Ep. 174

The Dairy Podcast Show

Play Episode Listen Later Dec 16, 2025 37:11


In this episode of The Dairy Podcast Show, Dr. Laura Hernandez from the University of Wisconsin-Madison shares groundbreaking insights on calcium regulation in dairy cows. She explains how serotonin, phosphorus, and prepartum management influence hypocalcemia outcomes and overall herd health. Listen now on all major platforms!"Serotonin moves calcium into the mammary gland through transporters to stimulate a hormonal signal that mobilizes calcium from the bone."Meet the guest: Dr. Laura Hernandez is a Professor of Lactation Biology at the University of Wisconsin-Madison. She earned her Ph.D. in Nutritional Sciences and Animal Science from the University of Arizona, following her M.S. and B.S. at New Mexico State University. Her research focuses on hormonal and metabolic pathways that regulate calcium homeostasis and mammary function in dairy cows.Liked this one? Don't stop now — Here's what we think you'll love!What you'll learn:(00:00) Highlight(01:33) Introduction(02:19) Research on calcium(04:15) Serotonin's calcium link(06:03) Hormonal regulation explained(14:33) Types of hypocalcemia(26:03) Future research areas(30:37) Final three questionsThe Dairy Podcast Show is trusted and supported by innovative companies like:Volac* Priority IAC* Lallemand* Adisseo* Afimilk* Evonik- Berg + Schmidt- SmaXtec- dsm-firmenich- ICC- Protekta- AHV- Natural Biologics

Buchty
Soulož s dobrmanem, úpadek venkova, francouzské sýry. I to je Houellebecqův Serotonin

Buchty

Play Episode Listen Later Dec 15, 2025 50:50


V dalším díle podcastového speciálu Buchty čtou o knížkách, které všichni známe, ale málokdo je skutečně četl, se Ivana Veselková, Zuzana Fuksová a středoškolský pedagog Stanislav Zajíček zabývali románem Michela Houellebecqa Serotonin.Všechny díly podcastu Buchty můžete pohodlně poslouchat v mobilní aplikaci mujRozhlas pro Android a iOS nebo na webu mujRozhlas.cz.

TRENDIFIER with Julian Dorey
#365 - Dr. K on LIES of Western Med, 3rd Spirituality Layer & Org*sms | Healthy Gamer GG

TRENDIFIER with Julian Dorey

Play Episode Listen Later Dec 12, 2025 205:40


SPONSORS: 1) RAG & BONE NEW YORK: Go to https://www.rag-bone.com/ and use code JULIAN for 20%! 2) AMENTARA: Go to https://www.amentara.com/go/julian and use code JD22 for 22% off your first order! PATREON https://www.patreon.com/JulianDorey ****TIMESTAMPS in description below**** - Alok M. Kanojia, also known as Dr. K., is an American psychiatrist and co-founder of the mental health coaching company Healthy Gamer. He streams interviews on Twitch, where he and participants discuss mental health topics. DR. K'S LINKS: YT: https://www.youtube.com/@HealthyGamerGG WEBSITE: https://www.healthygamer.gg X: https://twitter.com/HealthyGamerGG TikTok: https://www.tiktok.com/@healthygamer.gg IG: https://www.instagram.com/healthygamer_gg/ FOLLOW JULIAN DOREY INSTAGRAM (Podcast): https://www.instagram.com/juliandoreypodcast/ INSTAGRAM (Personal): https://www.instagram.com/julianddorey/ X: https://twitter.com/julianddorey JULIAN YT CHANNELS - SUBSCRIBE to Julian Dorey Clips YT: https://www.youtube.com/@juliandoreyclips - SUBSCRIBE to Julian Dorey Daily YT: https://www.youtube.com/@JulianDoreyDaily - SUBSCRIBE to Best of JDP: https://www.youtube.com/@bestofJDP ****TIMESTAMPS**** 0:00 – Intro 01:28 – Gaming Addiction, India Trip, Emotional Suppression, Meditation Paradox 13:26 – Diablo & Warcraft, Sent to India, Yogis & Temperature Control, Layers of Reality 23:59 – Yoga Physiology, Empty Stomach Rule, Diet & Meditation, Tai Chi Experiment 33:04 – Mind–Body Split, Gut Brain, Serotonin, Ayurveda, Inflammation Theory 42:53 – Eastern vs Western Medicine, Pills vs Hard Work, Laziness Debate 53:11 – Convenience Trap, Decision Fatigue, Habit Weakness, Flow State 01:04:01 – Habits vs Mental Training, Ignorance Causes Suffering, Residency Patient Story 01:15:49 – Consciousness, ADHD Patterns, Subconscious Decisions, Identity Formation 01:26:34 – Emotion vs Understanding, Experience Over Information, India Origins 01:35:30 – India Stories, Sensory Removal, Deep Meditation States 01:47:31 – Orgasm Addiction, Meditation, Nature of Thought 01:55:16 – Ashram Life, Yogic Purging, Bipolar vs Awakening, Advanced Practices 02:09:11 – Chi Experiment, Perception Training, Spiritual Plateau, Walking Discipline 02:20:49 – Losing Enlightenment Drive, Privilege Awareness, 7 Continents Kid 02:30:36 – Privilege, Emotional Evolution, Youth Mental Health Decline 02:41:36 – Fixing Mental Health Crisis, Systemic Issues, Incels, Natural Selection Pressure 02:51:46 – Tech & COVID, Eating Disorders, Cognitive Overload, The “Ick” 03:01:06 – Achievement ≠ Peace, Healthy Gamer Parenting, Trauma & Epigenetics 03:16:46 – PTSD Treatment, Trauma as Adaptation, Rewiring After Trauma 03:19:04 – Dr. K's work CREDITS: - Host, Editor & Producer: Julian Dorey - COO, Producer & Editor: Alessi Allaman - https://www.youtube.com/@UCyLKzv5fKxGmVQg3cMJJzyQ - In-Studio Producer: Joey Deef - https://www.instagram.com/joeydeef/ Julian Dorey Podcast Episode 365 - Dr. K (Healthy Gamer GG) Music by Artlist.io Learn more about your ad choices. Visit podcastchoices.com/adchoices

The Strategy Skills Podcast: Management Consulting | Strategy, Operations & Implementation | Critical Thinking
609: UCLA Professor and MD on How Gravity Shapes Your Health and Mind

The Strategy Skills Podcast: Management Consulting | Strategy, Operations & Implementation | Critical Thinking

Play Episode Listen Later Dec 10, 2025 52:33


Dr. Brennan Spiegel, Director of Health Services Research at Cedars-Sinai and Professor of Medicine and Public Health at UCLA, author of the book Pull, explains why illness is often a failure to manage gravity. He describes how our relationship with gravity defines strength, balance, digestion, mental stability, and emotional health.  Take the Gravotype Quiz at BrennanSpiegelMD.com to identify how your body manages gravity. Key Insights and Action Steps — Dr. Brennan Spiegel "Every single cell of your body evolved from this force of gravity. Physics came first, and biology came second." Illness arises when we fail to manage gravity. Every organ, tendon, and cell depends on that relationship. "When you stand up straight and lift your diaphragm, it pulls up this sack of potatoes that we all have in our belly. When you open up the gut, it opens up digestion." Posture determines how well the gut, diaphragm, and circulation function. Sitting compresses digestion and lowers energy. "Your balance and relationship to gravity is a predictor of how long you're going to live." Balance, grip strength, and posture are measurable indicators of longevity. "The inner ear is like a gyroscope constantly keeping track of your position in relation to gravity." The nervous system continuously measures gravity. Inner-ear disturbances can create dizziness, anxiety, and panic. "When you're depressed, you can't get up out of bed. Your body is slumped over. It's almost like there's so much gravity pulling on your body, it's like you're in a black hole." Depression mirrors an excessive gravitational load. Emotional heaviness is a physical experience of being pulled down. "Strong negative emotional experiences can permanently change the way the brain forms… the mind has learned to be pulled down emotionally, physically, socially." Childhood trauma reshapes how the brain perceives gravity, making the body feel heavier and slower to rise. "The feet are a gravity management surface… only five percent of the body's surface area but holding one hundred percent of the weight." Feet are the interface between body and planet. Strengthening them restores alignment and balance. "Your relationship to the planet, both latitudinally and altitudinally, will determine your health." Altitude, light, and environment influence serotonin, immunity, and microbiome function. "Serotonin itself is a gravity management substance." Serotonin regulates mood and physical stability, linking emotional and gravitational balance. "When it's stimulated, it activates the rest and digest phase and helps release serotonin." The vagus nerve is the primary connection between body and mind, calming the system and improving serotonin flow. "I pretended I was on a bigger planet… I became stronger and stood up straighter." Carrying additional resistance through weighted movement improves posture, strength, and metabolism. "When we lay down to sleep, we give our body a break… the blood easily flows into our brain and flushes out amyloid." Sleep restores gravitational equilibrium and supports brain recovery. "Gravity doesn't change, but your relationship to gravity does." Long-term health depends on strengthening that relationship physically, mentally, and emotionally. Action Items from Dr. Brennan Spiegel  1. Identify your gravotype. Take the 16-question quiz at BrennanSpiegelMD.com to learn which of the eight gravotypes you belong to and how your body manages gravity. 2. Build gravity fortitude. Strengthen the muscles and bones that keep you upright — especially your back, core, and legs. "When you stand up straight and lift your diaphragm, it pulls up the gut and opens digestion." 3. Stand tall and move often. Avoid long hours of sitting. Use a standing desk or take frequent standing breaks. Sitting compresses the abdomen, slows digestion, and reduces serotonin. 4. Strengthen the diaphragm and posture daily. Practice standing with shoulders back and chin level to engage the diaphragm and improve breathing and gut function. 5. Train your balance. Test and improve balance by standing on one leg, walking heel-to-toe, or using a balance board. "Your balance and relationship to gravity is a predictor of how long you're going to live." 6. Practice grip and hanging strength. Hang from a bar daily. Aim for 30 seconds, then increase gradually toward 2 minutes. Even short "dead hangs" improve shoulder, spine, and nervous-system alignment. 7. Use light weighted resistance. Try a weighted vest or light ankle weights while walking or doing chores. "I pretended I was on a bigger planet… I became stronger and stood up straighter." 8. Walk, run, or train barefoot or in minimalist shoes (safely). Let the feet feel the ground to activate stabilizing muscles. "When you ground your foot, everything else pulls up straight from there." 9. Reconnect with the ground. Spend time standing or walking on natural surfaces (grass, sand, earth) when possible. 10. Stay hydrated. Keep enough fluid in your body to "pump blood and oxygen up into the brain." Dehydration weakens gravity tolerance and causes dizziness or fatigue. 11. Regulate the nervous system. Do slow, controlled breathing through pursed lips to stimulate the vagus nerve and calm the body. "Slow meditative breathing activates the rest-and-digest phase." 12. Consider gentle vagus-nerve stimulation. Use only safe methods such as breathing, humming, or medical devices under supervision. Avoid carotid massage unless advised by a doctor. 13. Strengthen vestibular and proprioceptive awareness. Engage activities that challenge coordination: yoga, dance, gymnastics, tai chi, or balance training. 14. Manage mental gravity. Notice emotional heaviness as a physical sensation; practice posture, breathing, and grounding to counteract "mental black holes." 15. Use awe and nature to elevate mood. Spend time in nature, watch sunsets, or listen to music that evokes awe. "Feeling part of something greater than yourself elevates mood and serotonin." 16. Increase natural serotonin. Seek sunlight, exercise outdoors, connect socially, and reduce processed foods. Serotonin helps both mood and muscle tone to "fight gravity physically and mentally." 17. Optimize sleep for gravitational recovery. Sleep 7–8 hours flat or slightly inclined if you have reflux. Avoid heavy meals within 2 hours of sleep. Limit screens before bed. "When we lay down to sleep, we give our body a break… the blood easily flows into our brain." 18. Manage reflux and digestion. If prone to reflux, raise the head of the bed about 10 degrees or use a wedge pillow. Sleep on your left side to reduce acid reaching the esophagus. 19. Support circulation through movement. Use your muscles as pumps, walk regularly, stretch calves, and move legs during travel or desk work to prevent stagnation. 20. Avoid chronic compression. Reduce time bent over laptops or phones; keep screens at eye level to protect diaphragm and digestion. 21. Engage with natural environments. Nature exposure increases serotonin and improves gravity resilience. "Being in green spaces is mood-elevating because that's what we evolved with." 22. Monitor environment and altitude. If you live or work at high altitude, be mindful of mood or sleep changes and adjust oxygen exposure and sunlight time. 23. Balance convenience with movement. Spiegel warns that modern comfort, constant sitting, processed food, artificial environments, represents "our species losing the battle against gravity." 24. Reframe health. Adopt the mindset that "gravity doesn't change, but your relationship to gravity does." Everything, from mood to digestion, is part of managing that relationship.   Get Brennan's book, Pull, here: https://shorturl.at/XjNt3   Claim your free gift: Free gift #1 McKinsey & BCG winning resume www.FIRMSconsulting.com/resumePDF Free gift #2 Breakthrough Decisions Guide with 25 AI Prompts www.FIRMSconsulting.com/decisions Free gift #3 Five Reasons Why People Ignore Somebody www.FIRMSconsulting.com/owntheroom Free gift #4 Access episode 1 from Build a Consulting Firm, Level 1 www.FIRMSconsulting.com/build Free gift #5 The Overall Approach used in well-managed strategy studies www.FIRMSconsulting.com/OverallApproach Free gift #6 Get a copy of Nine Leaders in Action, a book we co-authored with some of our clients: www.FIRMSconsulting.com/gift

Ask Doctor Dawn
Vaccine Science: Anaphylaxis Prevention, Adjuvant Controversies, Fentanyl Immunization, Exercise Fighting Cancer, and Sunlight's Hidden Benefits

Ask Doctor Dawn

Play Episode Listen Later Dec 6, 2025 50:01


Broadcast from KSQD, Santa Cruz on 12-04-2025: Dr. Dawn opens with an experimental vaccine that prevents severe allergic reactions by targeting IgE antibodies. The vaccine could eventually replace current monoclonal antibody treatments like omalizumab that require injections every two weeks. She explains how adjuvants work in vaccines as additives that irritate the immune system enough to notice the vaccine target. Aluminum hydroxide is s common adjuvant. Modern vaccines use small pathogen fragments rather than whole organisms, requiring adjuvants to trigger adequate immune response. Dr. Dawn expresses concern about the US Advisory Committee on Immunization Practices reviewing aluminum adjuvants this week. A Danish study of over one million children finding no connection between aluminum with autism and ADHA contradicts RFK,Jr's public claims.She worries that removing aluminum could devastate vaccine effectiveness and children's health, noting that whenever vaccination rates drop, diseases like measles return to native circulation. She recounts pertussis vaccine history—when Japan stopped vaccination due to rare adverse reactions (approximately one death per million doses), they lost about 5,000 children to whooping cough in the first year. The newer acellular vaccine using pathogen fragments plus adjuvants is safer but only lasts 4-5 years versus lifetime immunity from the older whole-cell version, necessitating "cocooning" strategies where everyone contacting newborns must be recently vaccinated. Dr. Dawn describes a vaccine to prevent fentanyl from reaching the brain now starting clinical trials in the Netherlands. It pairs a fentanyl-like molecule with a carrier protein large enough to trigger antibody production. Once primed, the immune system attacks any fentanyl entering the blood, preventing highs and overdoses—potentially helping people in addiction recovery and those accidentally exposed through contaminated drugs. She reports the first documented death from alpha-gal syndrome. Alpha-gal is a meat allergy triggered by Lone Star tick bites; the tick essentially vaccinates humans against the alpha-galactosidase protein found on beef and pork. Cases have increased since 2010 as climate change expands the tick's range northward, yet a 2023 survey found 42% of doctors had never heard of the condition. Dr. Dawn highlights research from Edith Cowan University showing that blood drawn after exercise suppresses cancer cell growth when added to tumor cultures. In breast cancer survivors, plasma from high-intensity interval training or weight lifting caused cancer cells to stop growing or die; blood drawn before exercise had no effect. The key mechanism involves myokines, particularly IL-6, released by contracting muscles. A Stanford study found colon cancer survivors who exercised were 37% less likely to experience recurrence. A caller asks about pig-to-human heart transplants and mask recommendations. Dr. Dawn clarifies that newer xenotransplant pigs have more genes edited to reduce rejection compared to the 2022 case. For masking, she recommends context-dependent use—especially in public restrooms where toilet flushing aerosolizes COVID-containing particles, transportation hubs, and hospitals, noting that COVID vaccination prevents death but not infection or long COVID. She advises the same caller about spacing vaccines because adjuvant loads stack. Most vaccines can be combined safely, but she recommends against pairing COVID and Shingrix vaccines due to their heavy adjuvant content—wait at least ten days between them. She suggests inducing a sweat the night of vaccination through hot baths, saunas, or exercise to reduce adjuvant-related discomfort without diminishing antibody response. Dr. Dawn discusses seasonal affective disorder. She recommends 5,000 units of vitamin D3 and morning light exposure. She suggests that sun avoidance advice may have gone too far. A UK study of 3.36 million people found 12-15% lower mortality with greater UV exposure even accounting for skin cancer risk. A Swedish study following 30,000 women for 20 years found sun-seekers had half the mortality risk. Benefits may involve nitric oxide production lowering blood pressure, with each 1,000 km from the equator correlating with 5 mmHg higher blood pressure. Lack of bright outdoor light also contributes to childhood myopia, with rates exceeding 80% in some Asian cities. Dr. Dawn concludes with Danish microbiologists at Copenhagen's Alchemist restaurant reviving an old Bulgarian practice of fermenting milk with live red wood ants. The resulting yogurt, cheese, and ice cream contain far more beneficial microbes than commercial products, with a complex lemony acidity. Only live ants work, and wild ants may carry parasites dangerous to humans.

The James Smith Podcast
The Problem With Dopamine: TJ Power

The James Smith Podcast

Play Episode Listen Later Nov 25, 2025 110:54


Welcome to "The Problem With" where each week we look into a problem to get a better understanding of it. This podcast has no sponsors, only my businesses and investments. Please check out the links below.

Intelligent Medicine
Decadence with a Purpose: The Science Behind Healthy Chocolate, Part 1

Intelligent Medicine

Play Episode Listen Later Nov 25, 2025 34:30


Dr. Hoffman continues his conversation with Alan Frost, founder of Flava Naturals, and Dr. Joseph C. Maroon, MD, FACS, clinical professor and vice chairman of the Department of Neurological Surgery and Heindl Scholar in Neuroscience at the University of Pittsburgh Medical Center, and author of "The Science of Cocoa."

Intelligent Medicine
Decadence with a Purpose: The Science Behind Healthy Chocolate, Part 1

Intelligent Medicine

Play Episode Listen Later Nov 25, 2025 30:29


Alan Frost, founder of Flava Naturals, and Dr. Joseph C. Maroon, MD, FACS, clinical professor and vice chairman of the Department of Neurological Surgery and Heindl Scholar in Neuroscience at the University of Pittsburgh Medical Center, and author of "The Science of Cocoa," detail recent scientific findings on the cardiovascular and cognitive benefits of cocoa flavanols, the importance of sourcing and processing cocoa, and how cocoa can enhance athletic performance and brain health. The episode also covers the benefits of cocoa for skin health, fighting inflammation, and even mitigating some of the effects of sitting. Dr. Maroon elaborates on his protocols for concussion recovery, including the use of omega-3 fish oil, creatine, and CBD. The episode concludes with a discussion on how cocoa impacts mood and a special discount offer for Flava Naturals products. Just go to FlavaNaturals.com and use coupon code HOFFMAN20 for 20% off site-wide, plus get free shipping on all orders over $30.

Vitality Radio Podcast with Jared St. Clair
#589: The Hidden Epidemic Part 2: The Complete Endocrine Detox Strategy

Vitality Radio Podcast with Jared St. Clair

Play Episode Listen Later Nov 22, 2025 55:28


On this episode of Vitality Radio, Jared continues his deep dive into one of the most overlooked health threats of our time: endocrine-disrupting chemicals. If you haven't listened to Part 1 yet, hit pause and go back — the two episodes build on each other, and the full picture will make far more sense when heard in order.Here, we shift from identifying the problem to showing you how to clear it from your system naturally. This episode breaks down the detoxification phase of the long-awaited Endocrine Detox Protocol — built around four targeted formulas designed to support receptor clearance, liver pathways, gut integrity, and calcium balance to support healthy hormone signaling.If you've been struggling with stubborn symptoms, slow progress, or hormone fluctuations despite “doing everything right,” this episode will help you understand what's been missing — and how to finally address the upstream causes that matter.Products:LiverVitalityEndoCleanseBack On TractVital D3/K2 High PotencyVital D3/K2Magnesium BisglycinateAdditional Information:#588: The Hidden Epidemic Part 1: How Endocrine Disruptors Are Hijacking Your Health#507: Comprehensive Digestive Support to Get Your Gut ‘Back On Tract'!#565: D3, K2, Boron, and Silica: The Ultimate Synergy for Bones, Hormones, Arteries, and More!#258: Your Magnesium User's GuideVisit the podcast website here: VitalityRadio.comYou can follow @vitalitynutritionbountiful and @vitalityradio on Instagram, or Vitality Radio and Vitality Nutrition on Facebook. Join us also in the Vitality Radio Podcast Listener Community on Facebook. Shop the products that Jared mentions at vitalitynutrition.com. Let us know your thoughts about this episode using the hashtag #vitalityradio and please rate and review us on Apple Podcasts. Thank you!Just a reminder that this podcast is for educational purposes only. The FDA has not evaluated the podcast. The information is not intended to diagnose, treat, cure, or prevent any disease. The advice given is not intended to replace the advice of your medical professional.

Vitality Radio Podcast with Jared St. Clair
#588: The Hidden Epidemic Part 1: How Endocrine Disruptors Are Hijacking Your Health

Vitality Radio Podcast with Jared St. Clair

Play Episode Listen Later Nov 19, 2025 59:49


On this episode of Vitality Radio, Jared opens part one of a powerful new series on what he calls the hidden epidemic—the widespread and silent impact of endocrine-disrupting chemicals (EDCs) on hormones, brain chemistry, metabolism, and long-term health. After more than a year and a half of deep research, Jared and his wife Jen have uncovered how these chemicals mimic hormones, block receptors, interfere with detox pathways, disrupt neurotransmitters, and contribute to challenges like fatigue, low motivation, stubborn weight gain, PMS, anxiety, sleep struggles, and declining testosterone in both men and women.This episode explains why the endocrine system is struggling more than ever, how EDCs create thyroid chaos, hormonal imbalance, and neurochemical disruption, and what steps you can begin taking right now to start clearing these compounds from your environment and your body. If you've been dealing with symptoms that “don't match” your lab work, if you've struggled to feel balanced despite doing the right things, or if you've suspected environmental chemicals may be affecting you or your family, make sure to listen to Part 2 and stay tuned for future episodes. This is a big issue, but there are real answers and we are bringing them to you very soon on Vitality Radio.Products:LiverVitalityEndoCleanseBack On TractVital D3/K2Source Naturals Nattokinase 50mg - Vitality Radio POW! Product of the Week $11.99 per bottle (almost 70% off) with PROMO CODE: POW18Additional Information:Vitamin K2 and the Calcium Paradox: How a Little-Known Vitamin Could Save Your Life by Dr. Kate RhéaumeVisit the podcast website here: VitalityRadio.comYou can follow @vitalitynutritionbountiful and @vitalityradio on Instagram, or Vitality Radio and Vitality Nutrition on Facebook. Join us also in the Vitality Radio Podcast Listener Community on Facebook. Shop the products that Jared mentions at vitalitynutrition.com. Let us know your thoughts about this episode using the hashtag #vitalityradio and please rate and review us on Apple Podcasts. Thank you!Just a reminder that this podcast is for educational purposes only. The FDA has not evaluated the podcast. The information is not intended to diagnose, treat, cure, or prevent any disease. The advice given is not intended to replace the advice of your medical professional.

Naturally Nourished
Episode 470: SSRIs on the Rise: Concerns and Safer Alternatives

Naturally Nourished

Play Episode Listen Later Nov 17, 2025 52:39


SSRI prescriptions are more common than ever—but how much do we really understand about how they work, their true efficacy, and their potential downsides? In this episode, we take a deep dive into the world of SSRIs, breaking down their mechanism of action and why their use has skyrocketed in recent years.   We unpack the growing concern around emotional blunting, a well-documented effect that can leave individuals feeling flat, disconnected, or lacking drive. You'll learn why the serotonin deficiency model falls short, what SSRIs actually do in the brain, and why so many people are placed on them without a root-cause approach. We also explore powerful food-as-medicine and lifestyle strategies proven to support mood: from low-glycemic eating and amino acid repletion, to gut health, micronutrients, and more. If you're looking to understand the full picture of SSRIs and discover evidence-backed alternatives for mental wellness, this episode is a must-listen.   Also in this episode:  Free Detox Webinar Naturally Nourished Black Friday Starts Now - use code SAVE10 for 10% off all supplements Naturally Nourished Academy Now Enrolling with Early Bird Pricing Through 12/31 Give the Gift of Wellness with Naturally Nourished Gift Cards Episode 160: Neurotransmitters Part 1 The Anti Anxiety Diet What is Serotonin Sleep Support Low vs. High Serotonin What are SSRIs? Fu-Ming Zhou, Yong Liang, Ramiro Salas, Lifen Zhang, Mariella De Biasi, and John A. Dani: "Corelease of Dopamine and Serotonin from Striatal Dopamine Terminals" SSRIs and Violent Crime Associations between selective serotonin reuptake inhibitors and violent crime in adolescents, young, and older adults - a Swedish register-based study - PubMed Selective Serotonin Reuptake Inhibitors and Violent Crime: A Cohort Study | PLOS Medicine How to Naturally Boost Serotonin and Support Mood Protein Whey Protect Magnesium Role of magnesium supplementation in the treatment of depression: A randomized clinical trial | PLOS One Magnesium supplementation beneficially affects depression in adults with depressive disorder: a systematic review and meta-analysis of randomized clinical trials Relax and Regulate MethylFolate Assessing Effects of l-Methylfolate in Depression Management: Results of a Real-World Patient Experience Trial MethylComplete Movement Effect of exercise for depression: systematic review and network meta-analysis of randomised controlled trials | The BMJ Gaba GabaCalm Keto for Mental Health The use of the ketogenic diet in the treatment of psychiatric disorders - PMC Probiotics as Natures Prozac Acceptability, Tolerability, and Estimates of Putative Treatment Effects of Probiotics as Adjunctive Treatment in Patients With Depression: A Randomized Clinical Trial | Depressive Disorders | JAMA Psychiatry Probiotic Challenge Protocol   Sponsors for this episode:  This episode is sponsored by FOND Bone Broth, your sous chef in a jar. FOND's bone broths and tallows are produced in small batches with premium ingredients from verified regenerative ranches. Their ingredients are synergistically paired for maximum absorption, nutritional benefit, and flavor. Use code ALIMILLERRD to save at https://fondbonebroth.com/ALIMILLERRD.   

Dr. Joseph Mercola - Take Control of Your Health
Fat Metabolism Holds the Key to Why We Need Sleep

Dr. Joseph Mercola - Take Control of Your Health

Play Episode Listen Later Nov 12, 2025 8:36


Sleep is not just downtime but a built-in survival mechanism that protects your brain from toxic byproducts created when mitochondria leak electrons New research shows that the more electrons your cells fail to use, the greater the buildup of reactive oxygen species, which directly triggers your need for sleep Excessive fat burning under stress makes this problem worse by clogging energy pathways, depleting cofactors, and pushing your body into deep fatigue Serotonin levels rise when fatty acids flood your system, creating another pathway that drives drowsiness and heavy sleep pressure Supporting your mitochondria with healthy carbs, avoiding extreme cardio, and limiting harmful fats found in seed oils lowers electron leaks, reduces sleep demand, and helps you feel more energized

The Dr. Gabrielle Lyon Show
Neuroscientist Explains MDMA and The Science of Social Connection | Dr. Ben Rein Ph.D.

The Dr. Gabrielle Lyon Show

Play Episode Listen Later Nov 11, 2025 87:17


Pre-Order The Forever Strong PLAYBOOK and receive exclusive bonuses: https://drgabriellelyon.com/playbook/Want ad-free episodes, exclusives and access to community Q&As? Subscribe to Forever Strong Insider: https://foreverstrong.supercast.comIn this fascinating episode, Dr. Gabrielle Lyon talks with neuroscientist Dr. Ben Rein, PhD (author of Why Brains Need Friends), about the science of social connection, emotion, and cognitive health. Dr. Rein, an expert in neurobiology and psychedelic research, reveals the cutting-edge studies that explain why loneliness is as damaging as smoking and how our digital world is affecting our brain's ability to connect.They discuss the neurochemistry of love, the controversial use of MDMA in therapy, and whether AI can ever truly replace human intimacy. This conversation provides an essential look at the biological drivers of happiness, performance, and long-term brain health.Chapter Markers:0:00 - MDMA (Molly): The History & Therapeutic Benefits 5:59 - The Legal Status of MDMA for PTSD 6:44 - The Safety and Effectiveness of MDMA in Clinical Trials 8:29 - PTSD (The Amygdala Alarm) 9:41 - How MDMA Soothes the Amygdala to Access Memory 11:42 - Is There an Alternative to MDMA? (Ketamine's Mechanism) 13:16 - Ketamine and Neuroplasticity for Depression 15:48 - Botox and Empathy: 18:12 - The Problem of Volume: How Screens Depersonalize Interaction 19:48 - The Virtual Disengagement Hypothesis Explained 25:00 - Defining Cognitive and Emotional Empathy 29:43 - MDMA's Link to Serotonin & Social Reward 31:04 - Do SSRIs Have Pro-Social Effects? 36:10 - The Science of Likability and "Easy to Read" Faces 40:10 - Top 3 Ways to Be More Likable49:49 - The Likability Gap: Why You Underestimate How Well-Liked You Are 56:59 - The Neurobiology of Oxytocin, Dopamine, and Serotonin1:09:23 - The Goldilocks Zone of Empathy 1:15:58 - Narcolepsy 1:18:16 - Alcohol: Why the Neurotoxin is Bad for Brain Health 1:21:47 - Exercise and Neurogenesis1:22:27 - Sex, Orgasm, and Oxytocin Release 1:25:06 - Oxytocin During Childbirth Who is Ben Rein:Dr. Ben Rein is an award-winning neuroscientist and Chief Science Officer of the Mind Science Foundation, where he supports early-career researchers in neuroscience. He earned his PhD from SUNY Buffalo and completed postdoctoral training at Stanford University, publishing over 20 peer-reviewed papers on autism, empathy, MDMA, and digital behavior. Recognized by the NIH, the Society for Neuroscience, and Sigma Xi, he also serves as a scientific advisor to more than 20 organizations. With over one million followers and 75 million video views, Dr. Rein is celebrated for making neuroscience accessible to the public and has been featured by outlets such as Good Morning America, ABC News, and PopularMechanics.Thank you to our sponsors:BodyHealth: Use code LYON20 to get 20% off your first order https://www.bodyhealthaffiliates.com/73L4QL3/7XDN2/BON CHARGE Holiday Sale https://boncharge.com for 25% off Pique 20% off for life: https://Piquelife.com/DRLYONFind Ben Rein at: Website: https://www.benrein.com/Instagram: https://www.instagram.com/dr.benrein/#TikTok: https://www.tiktok.com/@dr.benrein?lang=enFacebook:

Kwik Brain with Jim Kwik
The 4 Chemicals Secretly Controlling Your Motivation and Mood

Kwik Brain with Jim Kwik

Play Episode Listen Later Nov 10, 2025 27:07


Did you know four brain chemicals secretly control your motivation, mood, and mental energy every single day?In this episode, Jim sits down with neuroscientist and bestselling author TJ Power to break down the DOSE Effect. It is a science backed framework for activating the four key neurochemicals that shape your daily experience: Dopamine, Oxytocin, Serotonin, and Endorphins.TJ shares how our modern digital lifestyles are draining these natural feel good chemicals and how you can rebalance them through small, evidence based habits. You will learn the difference between natural and artificial dopamine, how to boost oxytocin through real human connection, the serotonin and sunlight link that stabilizes your mood, and the surprising power of endorphins to calm stress.You will also hear why technology is hijacking your motivation system, how to design your environment to protect your brain, and a simple daily ritual to reset your chemistry in under five minutes.By the end, you will have a clear roadmap to upgrade your focus, energy, and emotional balance without relying on caffeine, willpower, or scrolling.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Dr. Joseph Mercola - Take Control of Your Health
Revisiting Depression — Dopamine-Serotonin Balance Gains Attention for Treatment-Resistant Depression

Dr. Joseph Mercola - Take Control of Your Health

Play Episode Listen Later Nov 10, 2025 7:25


A major clinical trial in The Lancet Psychiatry found that boosting dopamine with pramipexole improved symptoms in treatment-resistant depression. This challenges the long-dominant serotonin deficiency theory Supporting those findings, another study showed that agomelatine, a serotonin-blocking drug, consistently reduced anxiety and depression in multiple placebo-controlled trials Research shows polyunsaturated and monounsaturated fats (PUFs and MUFs) directly trigger platelet aggregation and serotonin release, while saturated fats do not, linking modern diets to serotonin excess Studies confirm that combinations of unsaturated fats amplify serotonin release even at sub-threshold levels, making everyday dietary choices especially relevant to serotonin-driven health risks and mood instability Increasing GABA helps your body break down serotonin, restoring calm, better sleep, and mood stability without SSRI side effects, making it a safer alternative for addressing depression and anxiety

Huberman Lab
Essentials: The Science of Gratitude & How to Build a Gratitude Practice

Huberman Lab

Play Episode Listen Later Oct 23, 2025 39:31


In this Huberman Lab Essentials episode, I explore the science of gratitude and how to develop an effective, research-supported gratitude practice. I explain why common gratitude practices (like simply listing things you're grateful for) are far less impactful than engaging in story-based gratitude practices. I also explain how being grateful activates specific brain regions, which enhance calm, social connection and motivation, while reducing anxiety and inflammation. Finally, I share why we can't simply trick our brains into feeling grateful and describe a practical weekly gratitude practice that will improve both your mental and physical well-being. Read the episode show notes at hubermanlab.com. Thank you to our sponsors AGZ by AG1: https://drinkagz.com/huberman Eight Sleep: https://eightsleep.com/huberman Our Place: https://fromourplace.com/huberman Timestamps (0:00) Gratitude (0:30) Gratitude Practice Benefits (3:22) Pro-Social vs Defensive Behaviors, Gratitude (6:25) Sponsor: Eight Sleep (8:07) Serotonin, Brain & Context, Gratitude Mindset (14:02) Context, Can You Lie to Yourself? (14:48) Effective Gratitude Practice, Tools: Receiving Gratitude, Story (21:18) Sponsor: AGZ by AG1 (22:47) Tool: Find & Revisit Inspirational Stories (27:30) Heartfelt Intention, Genuine Thanks (29:42) Sponsor: Our Place (31:03) Gratitude Practice Benefits for Anxiety, Fear & Motivation (33:29) Gratitude Practice Benefits for Immune System (36:02) Recap: Establishing an Effective Gratitude Practice Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices

The Human Upgrade with Dave Asprey
These Plants Turn On 1,100 Healing Genes In 24 Hours (Ancient Biohacks) : 1346

The Human Upgrade with Dave Asprey

Play Episode Listen Later Oct 16, 2025 56:52


Most people try to “heal” their brain with supplements, mindset, or meditation—but this episode reveals the deeper protocol to actually grow a new brain, reverse stress damage, activate 1,100 healing genes, and unlock higher human performance at any age. You'll learn how neuroplasticity, mitochondria repair, plant-based NRF2 activators, and energetic practices work together to rebuild the brain and extend longevity. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Alberto Villoldo, Ph.D.—medical anthropologist, neuroscientist, energy medicine pioneer, and founder of The Four Winds Society, the gold-standard school for modern shamans. He has spent 25+ years studying Amazonian and Andean healing traditions, led the Biological Self-Regulation Lab at San Francisco State University to explore psychosomatic medicine, and authored more than 25 bestselling books on neuroscience, functional medicine, and energy healing. Few people on earth bridge ancient biohacking and modern brain science at this level. He also reveals the forms of nicotine that are safest (spoiler: it's not vapes or cigarettes), how nicotine works at the receptor level, and what the science says about long-term health effects. This episode blends functional medicine, brain optimization, and biohacking into one powerful, myth-busting breakdown. You'll learn: • How to grow a new brain every 22 days using neuroplasticity and mitochondria support • Why plant medicines and NRF2 activators can turn on 1,100 healing genes in 24 hours • The surprising link between nootropics, psychedelics, serotonin, and endogenous DMT • How mindset, belief systems, and placebo/nocebo shape immune function and metabolism • Why RFK's chronic disease warning connects to viral evolution and immune collapse • The real reason carnivore diets work—and when they fail without gut repair • Peptides, GLP-1 agonists, and the future of functional medicine hacking • Why most people sabotage themselves and how to stop fighting your own biology This is essential listening for anyone serious about biohacking, human performance, and longevity, and for those who want to understand how functional biology and mitochondrial science are redefining recovery, energy, and aging. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: NRF2 activation, Neurogenesis and hippocampus repair, Plant-based epigenetic triggers, Psychosomatic health, Serotonin to DMT conversion, Pineal gland methylation, Parasites and brain inflammation, Viral-driven evolution, GLP-1 agonists and longevity, Psilocybin lifespan extension, Autophagy and brain cleanup, Energetic medicine training, Functional peptides, BPC-157, Breathwork and CO2 tolerance, mTOR cycling, Cold exposure and dopamine, Mindset-driven immune function Thank you to our sponsors! • EMR-Tek | https://www.emr-tek.com/DAVE and use code DAVE for 40% off. • Essentia | Go to https://myessentia.com/dave and use code DAVE for $100 off The Dave Asprey Upgrade. • Timeline | Head to https://www.timeline.com/dave to get 10% off your first order. • fatty15 | Go to https://fatty15.com/dave and save an extra $15 when you subscribe with code DAVE. Resources: • Learn more from Alberto at: www.thefourwinds.com and www.albertovilloldo.net • Buy the book ‘Grow A New Brain': https://a.co/d/5lVhrVy • Business of Biohacking | Register to attend October 20-23 in Austin, TX https://businessofbiohacking.com/ • Danger Coffee: https://dangercoffee.com/discount/dave15 • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 — Trailer 1:25 — Introduction & Ayahuasca Story 3:15 — Shamanism Beyond Plant Medicine 6:53 — Losing Your Mind to Evolve 10:45 — The 22-Day New Brain Cycle 12:53 — Plant Communication & Direct Knowing 15:35 — Parasites, Liver Failure & Brain Damage 20:25 — Remote Healing & CIA Research 22:40 — Tryptophan, Turkey Farmers & Brain Chemistry 25:19 — Viruses as Evolutionary Drivers 30:30 — Psilocybin & Life Extension 35:25 — Healing with Mindset + Biology 38:52 — Spirit, Purpose & Growing Gods 43:49 — Plants, Protein & mTOR 49:07 — Training the Four Brains 51:16 — Cold Exposure: Pain vs Suffering 54:40 — Who Am I? Living the Question 55:25 — Closing See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Huberman Lab
Essentials: Time Perception, Memory & Focus

Huberman Lab

Play Episode Listen Later Oct 9, 2025 33:55


In this Huberman Lab Essentials episode, I explore how biological rhythms and neurochemicals impact our perception of time. I describe how the body aligns with daily and seasonal light cycles to regulate hormones that influence energy, mood and motivation throughout the year. I share science-based tools to enhance focus and productivity, including strategies for structuring work intervals and optimizing the timing of exercise and daily light exposure. I also explain how neurotransmitters like dopamine and serotonin influence our perception of time and how factors such as novelty, emotion and routine impact how we experience and recall time. Read the episode show notes at hubermanlab.com. Thank you to our sponsors AGZ by AG1: https://drinkagz.com/huberman BetterHelp: https://betterhelp.com/huberman Timestamps (0:00) Time Perception (0:48) Entrainment, Circannual Rhythms & Melatonin (4:22) Circadian Rhythms, Tools: Exercise; Morning & Evening Light for Circadian Entrainment (9:01) Sponsor: AGZ by AG1 (10:30) Ultradian Cycles, Focus & Work (14:06) Time Perception, Past, Present & Future (16:21) Dopamine, Norepinephrine & Serotonin, Time Perception (18:40) Dopamine & Serotonin, Daily Fluctuations, Tool: Structuring Work, Sleep (20:23) Trauma, “Over-clocking”, Slowing Time & Emotions (24:59) Sponsor: BetterHelp (26:15) Event Perception (Fun vs Boring), Time & Memories (29:23) Novel Experiences, Places & People, Retrospective Time (31:24) Habits, Tool: Schedule Functional Units (32:59) Recap & Book Suggestion Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices