Podcasts about antibiotic therapy

In this episode of The SHEA Podcast, SHEA Journal Club Chair and moderator Hannah Imlay is joined by guests Jennifer Cihlar and David Cluck to discuss two of the most impactful articles reviewed by the journal club this year. The first article, "Bacteremia From a Presumed Urinary Source in Hospitalized Adults With Asymptomatic Bacteriuria" by Advani SD, Ratz D, Horowitz JK, et al., examines the clinical implications of asymptomatic bacteriuria in hospitalized adults. The second article, "Identifying Effective Durations of Antibiotic Therapy for the Treatment of Carbapenem-resistant Enterobacterales Bloodstream Infections: A Multicenter Observational Study" by Soto CL, Hsu AJ, Lee JH, et al., explores optimal antibiotic treatment durations for these challenging infections. Join us for an in-depth discussion on the findings and clinical impacts of these studies.

In today's episode, Dr. Rachael Forsythe (@ROForsythe), consultant vascular surgeon at NHS Lothian, leads a fictional case-based discussion with leaders in managing diabetic foot ulcers. Joining the conversation are Professor Andrew Boulton, Mr. Patrick Coughlin, Dr. David Armstrong, Dr. Dane Wukich, and Dr. Edgar Peters. Professor Boulton is a professor of medicine at Manchester University in England and is co-chair of the Malvern  Diabetic Foot Conference meeting. He served as president of numerous distinguished societies, including the International Diabetes Federation. Dr.  Coughlin (@Coughlin_pa) is a consultant vascular surgeon in Leeds, England. He is a very active member of the Vascular Society of Great Britain and Ireland Council and has a special academic and clinical interest in peripheral artery disease. Dr. Armstrong (@DGArmstrong) is a podiatric surgeon and professor of surgery at Keck School of Medicine of the University of California and director of the Southwestern Academic Limb Salvage Alliance. Dr. Armstrong is very well known for his work on amputation prevention, the diabetic foot and wound healing. Dr. Wukich (@DaneWukich) is a professor and chair of the Department of Orthopedics at the University of Texas, Southwestern and Medical Director of Orthopedic Surgery at UT Southwestern University Hospitals. Dr. Wich has an interest in foot and ankle surgery, including the management of diabetes-related complications. Dr. Edgar Peters is an associate professor of internal medicine, infectious diseases, and acute medicine at Amsterdam University Medical Centers, Dr. Peter's main interest is infection of the musculoskeletal system, particularly in patients with diabetes and is the Scientific Secretary of the International Symposium on the Diabetic Foot.    Malvern Diabetic Foot Conference info: https://www.facebook.com/MalvernDiabeticFootConference/ https://eu.eventscloud.com/website/8151/   If this episode was of interest to you, please take a listen to this Transatlantic Series episode where we speak with the authors of the SVS, ESVS, and IWGDFU joint guidelines on the management of peripheral arterial disease (PAD) in patients with diabetes.    Articles, resources, and societies referenced in the episode: DF Blog. “Oral Is the New IV. Challenging Decades of Blood and Bone Infection Dogma: A Systematic Review @bradspellberg @lacuscmedcenter @usc,” January 1, 2022. https://diabeticfootonline.com/2022/01/01/oral-is-the-new-iv-challenging-decades-of-blood-and-bone-infection-dogma-a-systematic-review-bradspellberg-lacuscmedcenter-usc/. Gariani, Karim, Truong-Thanh Pham, Benjamin Kressmann, François R Jornayvaz, Giacomo Gastaldi, Dimitrios Stafylakis, Jacques Philippe, Benjamin A Lipsky, and Lker Uçkay. “Three Weeks Versus Six Weeks of Antibiotic Therapy for Diabetic Foot Osteomyelitis: A Prospective, Randomized, Noninferiority Pilot Trial.” Clinical Infectious Diseases 73, no. 7 (October 5, 2021): e1539–45. https://doi.org/10.1093/cid/ciaa1758. Li, Ho-Kwong, Ines Rombach, Rhea Zambellas, A. Sarah Walker, Martin A. McNally, Bridget L. Atkins, Benjamin A. Lipsky, et al. “Oral versus Intravenous Antibiotics for Bone and Joint Infection.” New England Journal of Medicine 380, no. 5 (January 31, 2019): 425–36. https://doi.org/10.1056/NEJMoa1710926. Magliano, Dianna, and Edward J. Boyko. IDF Diabetes Atlas. 10th edition. Brussels: International Diabetes Federation, 2021. Østergaard, Lauge, Mia Marie Pries-Heje, Rasmus Bo Hasselbalch, Magnus Rasmussen, Per Åkesson, Robert Horvath, Jonas Povlsen, et al. “Accelerated Treatment of Endocarditis—The POET II Trial: Ration ale and Design of a Randomized Controlled Trial.” American Heart Journal 227 (September 2020): 40–46. https://doi.org/10.1016/j.ahj.2020.05.012. Price, Patricia. “The Diabetic Foot: Quality of Life.” Clinical Infectious Diseases 39 (2004): S129–31. Sharma, S., C. Kerry, H. Atkins, and G. Rayman. “The Ipswich Touch Test: A Simple and Novel Method to Screen Patients with Diabetes at Home for Increased Risk of Foot Ulceration.” Diabetic Medicine: A Journal of the British Diabetic Association 31, no. 9 (September 2014): 1100–1103. https://doi.org/10.1111/dme.12450. Shin, Laura, Frank L. Bowling, David G. Armstrong, and Andrew J.M. Boulton. “Saving the Diabetic Foot During the COVID-19 Pandemic: A Tale of Two Cities.” Diabetes Care 43, no. 8 (August 1, 2020): 1704–9. https://doi.org/10.2337/dc20-1176. Tone, Alina, Sophie Nguyen, Fabrice Devemy, Hélène Topolinski, Michel Valette, Marie Cazaubiel, Armelle Fayard, Éric Beltrand, Christine Lemaire, and Éric Senneville. “Six-Week Versus Twelve-Week Antibiotic Therapy for Nonsurgically Treated Diabetic Foot Osteomyelitis: A Multicenter Open-Label Controlled Randomized Study.” Diabetes Care 38, no. 2 (February 1, 2015): 302–7. https://doi.org/10.2337/dc14-1514. Wukich, Dane K., Katherine M. Raspovic, and Natalie C. Suder. “Patients With Diabetic Foot Disease Fear Major Lower-Extremity Amputation More Than Death.” Foot & Ankle Specialist 11, no. 1 (February 2018): 17–21. https://doi.org/10.1177/1938640017694722.

Show notes at pharmacyjoe.com/episode883. In this episode, I'll discuss what phenotype of patients are most affected by delays in antibiotic therapy. The post 883: What Are Characteristics of Patients That Are More Likely To Die If Antibiotic Therapy Is Delayed? appeared first on Pharmacy Joe.

Show notes at pharmacyjoe.com/episode883. In this episode, I ll discuss what phenotype of patients are most affected by delays in antibiotic therapy. The post 883: What Are Characteristics of Patients That Are More Likely To Die If Antibiotic Therapy Is Delayed? appeared first on Pharmacy Joe.

In this crossover episode of BackTable OBGYN with Urology, Dr. Suzette Sutherland, Director of Female Urology at the University of Washington, and Dr. Anne Cameron, Professor of Urology at the University of Michigan, share their insights on the prevention and management of urinary tract infections (UTIs). First, they emphasize the importance of dispelling misconceptions about recurrent UTIs being a result of poor hygiene or incorrect behaviors, explaining that they can stem from genetic or hormonal risk factors. Dr. Cameron describes her algorithm for managing UTIs in specific patient populations. She further discusses the impact of factors such as fluid intake, bowel habits, and vaginal health on the incidence of UTIs. Dr. Cameron also highlights the potential for UTIs in diabetic patients on certain medications and the importance of a collaborative approach with diabetic healthcare teams. Additionally, the doctors explore various treatment strategies, such as cranberry supplements and gentamicin bladder installations, cautioning against antibiotic overuse due to the risk of resistance. --- EARN CME Reflect on how this Podcast applies to your day-to-day and earn free AMA PRA Category 1 CMEs: https://earnc.me/2P5fzK --- SHOW NOTES 00:00 - Introduction 02:13 - Understanding UTIs: Definitions, Symptoms, and Prevalence 04:39 - Recurrent UTIs: Definitions, Causes, and Treatment Challenges 12:00 - Understanding Asymptomatic Bacteriuria 15:00 - Cystitis vs. Pyelonephritis vs. Urosepsis 20:57 - Antimicrobial Resistance and Antibiotic Stewardship 24:36 - Treatment Guidelines for UTIs 31:13 - Self-start Antibiotic Therapy for UTIs 34:37 - Preventing UTIs: Hydration, Lifestyle Factors, and Bowel Health 38:33 - The Connection Between Vaginal Health and UTIs 42:40 - The Role of Supplements in UTI Prevention: D-Mannose and Cranberry, and Methenamine Hippurate 57:18 - Identification and Treatment of UTIs in Patients with Indwelling Catheters 01:00:04 - The Role of Gentamicin Bladder Installations in UTI Prevention 01:04:27 - The Impact of Diabetes Medications on UTIs --- RESOURCES AUA Guidelines for UTI Treatment: https://www.auanet.org/guidelines-and-quality/guidelines/recurrent-uti

In this crossover episode of BackTable OBGYN with Urology, Dr. Suzette Sutherland, Director of Female Urology at the University of Washington, and Dr. Anne Cameron, Professor of Urology at the University of Michigan, share their insights on the prevention and management of urinary tract infections (UTIs). First, they emphasize the importance of dispelling misconceptions about recurrent UTIs being a result of poor hygiene or incorrect behaviors, explaining that they can stem from genetic or hormonal risk factors. Dr. Cameron describes her algorithm for managing UTIs in specific patient populations. She further discusses the impact of factors such as fluid intake, bowel habits, and vaginal health on the incidence of UTIs. Dr. Cameron also highlights the potential for UTIs in diabetic patients on certain medications and the importance of a collaborative approach with diabetic healthcare teams. Additionally, the doctors explore various treatment strategies, such as cranberry supplements and gentamicin bladder installations, cautioning against antibiotic overuse due to the risk of resistance. --- EARN CME Reflect on how this Podcast applies to your day-to-day and earn free AMA PRA Category 1 CMEs: https://earnc.me/2P5fzK --- SHOW NOTES 00:00 - Introduction 02:13 - Understanding UTIs: Definitions, Symptoms, and Prevalence 04:39 - Recurrent UTIs: Definitions, Causes, and Treatment Challenges 12:00 - Understanding Asymptomatic Bacteriuria 15:00 - Cystitis vs. Pyelonephritis vs. Urosepsis 20:57 - Antimicrobial Resistance and Antibiotic Stewardship 24:36 - Treatment Guidelines for UTIs 31:13 - Self-start Antibiotic Therapy for UTIs 34:37 - Preventing UTIs: Hydration, Lifestyle Factors, and Bowel Health 38:33 - The Connection Between Vaginal Health and UTIs 42:40 - The Role of Supplements in UTI Prevention: D-Mannose and Cranberry, and Methenamine Hippurate 57:18 - Identification and Treatment of UTIs in Patients with Indwelling Catheters 01:00:04 - The Role of Gentamicin Bladder Installations in UTI Prevention 01:04:27 - The Impact of Diabetes Medications on UTIs --- RESOURCES AUA Guidelines for UTI Treatment: https://www.auanet.org/guidelines-and-quality/guidelines/recurrent-uti

Traditionally long-term antibiotic therapy for significant infections has been given intravenously (IV). Current evidence now supports the utilisation of highly bioavailable oral antibiotic (HBOA) therapy substituting for most of the IV course. This includes quinolones, sulphonamides, tetracyclines, macrolides, azoles, lincosamides, rifamycins and oxazolidinones classes of antibiotics. HBOA therapy allows the patient to receive treatment in their own home, potentially return to work, removes the risk of long lines, and achieve therapeutic goals. However, treatment may be for several months and side effects may arise at any time; some potentially avoidable with early recognition. We established a Complex outpatient antibiotic therapy (CoPAT) service that monitor's patients on HBOA at home. This manages in a timely fashion any adverse outcomes to allow ongoing achievement of therapeutic goals, prevention of hospital admission and reduction of overall care costs. It also allows standardisation of the follow-up care provided.

Antibiotic resistance is a growing threat, silently undermining our ability to combat infections and urging us to find innovative solutions before it's too late. Today we are joined by Connecticut-based oral maxillofacial surgeon, Dr. David Salomon to explore the ever-evolving landscape of antibiotic practices and the importance of staying up-to-date, especially when it comes to treating serious infections. Dr. Salomon discusses the fundamental principles of antibiotic therapy, including appropriate selection and administration, before delving into the pressing issue of antibiotic resistance and the necessity of using narrow-spectrum antibiotics to combat this problem effectively. Understanding the duration of antibiotic treatment and prophylaxis is crucial, as it varies with each individual case. Dr. Salomon highlights the significance of considering sensitivities before administering antibiotics, along with indications for antimicrobial use and the heightened risk faced by immunocompromised patients. We explore alternative antibiotics for penicillin-allergic patients and discover why it's so crucial for us to improve our understanding and adherence to prophylactic protocols in dental surgery. Tune in for invaluable insights into the world of antibiotics and their role in personalized care!Key Points From This Episode:Introducing Connecticut-based oral maxillofacial surgeon, Dr. David Salomon.The evolving nature of antibiotic practices and the importance of staying updated, particularly for serious infections.Principles of antibiotic therapy, including appropriate selection and administration.Antibiotic resistance and the need for narrow-spectrum antibiotics.How the duration of antibiotic treatment and prophylaxis varies based on individual cases.The importance of taking sensitivities into consideration before administering antibiotics.Indications for antimicrobial use and increased risk for immunocompromised patients.Alternative antibiotics for penicillin-allergic patients.Why antibiotic prophylaxis is used for dental procedures.Treatment approaches for severe infections and special circumstances.The importance of biopsy and culturing for accurate diagnosis and treatment.Why preoperative prophylactic antibiotics are recommended for surgical procedures.Azithromycin as an alternative for oral prophylaxis in penicillin-allergic patients.The need for better understanding and adherence to prophylactic protocols in dental surgery.Dr. Salomon's preferred number of chains and links in expose and bond procedures.Thanks for listening!Links Mentioned in Today's Episode:Dr. David Salomon — https://www.linkedin.com/in/david-salomon-b8ab1431KLS Martin Summer Sale Special — klsmartin.com (Promo code: EOSSummer2023)Everyday Oral Surgery Website — https://www.everydayoralsurgery.com/ Everyday Oral Surgery on Instagram — https://www.instagram.com/everydayoralsurgery/ Everyday Oral Surgery on Facebook — https://www.facebook.com/EverydayOralSurgery/Dr. Grant Stucki Email — grantstucki@gmail.comDr. Grant Stucki Phone — 720-441-6059

Oral antibiotics are frequently used to treat moderate to severe acne. In the first podcast in this 3-part series, Christopher Bunick, MD, PhD, Associate Professor of Dermatology, Yale School of Medicine, New Haven, Connecticut, discusses indications, concerns, and improvements in oral antibiotic therapy for acne.

Dr. Laura Certain (@laura_certain) and Dr. Nico Cortes-Penfield (@Cortes_Penfield) join Dr. Julie Ann Justo (@julie_justo) to discuss all things related to prosthetic joint infections. Tune in to learn about what comprises a bacterial biofilm, how it develops, and ways to combat it using the latest evidence-based antibiotic regimens. We also take a look at what's on the horizon for the field of orthopedic infectious diseases. Learn more about the Society of Infectious Diseases Pharmacists: https://sidp.org/About Twitter: @SIDPharm (https://twitter.com/SIDPharm) Instagram: @SIDPharm (https://www.instagram.com/sidpharm/) Facebook: https://www.facebook.com/sidprx LinkedIn: https://www.linkedin.com/company/sidp/ References: Cortés-Penfield NW, Kulkarni PA. The History of Antibiotic Treatment of Osteomyelitis. Open Forum Infect Dis. 2019 Apr 8;6(5):ofz181. doi: 10.1093/ofid/ofz181. PMID: 31123692. Bernard L, et al. Antibiotic Therapy for 6 or 12 Weeks for Prosthetic Joint Infection. N Engl J Med. 2021 May 27;384(21):1991-2001. doi: 10.1056/NEJMoa2020198. PMID: 34042388. (DATIPO trial) Gallagher C, et al. Impact of Implementing an IV to PO Antibiotic Treatment Protocol for Orthopedic Infections ion Prescribing Habits and Health Utilization Outcomes. IDWeek 2022. Poster 909. Febrile Podcast. Episode #31 – Truth or DAIR. 2022 Feb 28. https://febrilepodcast.com/episode-31-truth-or-dair/ Frank JM, et al. The Mark Coventry, MD, Award: Oral Antibiotics Reduce Reinfection After Two-Stage Exchange: A Multicenter, Randomized Controlled Trial. Clin Orthop Relat Res. 2017 Jan;475(1):56-61. doi: 10.1007/s11999-016-4890-4. PMID: 27387759. Kelly MP, et al. Extended Oral Antibiotics Increase Bacterial Resistance in Patients Who Fail 2-Stage Exchange for Periprosthetic Joint Infection. J Arthroplasty. 2022 Aug;37(8S):S989-S996. doi: 10.1016/j.arth.2022.01.027. PMID: 35074446. Payne J, et al. Inducing Antimicrobial Resistance with Long-term Antibiotics at Stage 2 Revision for Periprosthetic Joint Infection. IDWeek 2022. Poster 981. Frost P, et al. Phototoxic potential of minocycline and doxycycline. Arch Dermatol. 1972 May;105(5):681-3. PMID: 5026677. Lode H, et al. Comparative pharmacokinetics of cephalexin, cefaclor, cefadroxil, and CGP 9000. Antimicrob Agents Chemother. 1979 Jul;16(1):1-6. doi: 10.1128/AAC.16.1.1. PMID: 475366. Sader HS, et al. In vitro activity of cefpodoxime compared with other oral cephalosporins tested against 5556 recent clinical isolates from five medical centers. Diagn Microbiol Infect Dis. 1993 Aug-Sep;17(2):143-50. doi: 10.1016/0732-8893(93)90025-3. PMID: 8243035. Green S & Tsai YV. Precision Dosing of To-Marrow: Linezolid Therapeutic Drug Monitoring. ContagionLive: Bench to Bedside with SIDP. 2022 Nov 3. https://www.contagionlive.com/view/precision-dosing-of-to-marrow-linezolid-therapeutic-drug-monitoring Check out our podcast host, Pinecast. Start your own podcast for free with no credit card required. If you decide to upgrade, use coupon code r-7e7a98 for 40% off for 4 months, and support Breakpoints. Check out our podcast host, Pinecast. Start your own podcast for free with no credit card required. If you decide to upgrade, use coupon code r-7e7a98 for 40% off for 4 months, and support Breakpoints.

Brad Spellberg, MD, FIDSA, FACP, Chief Medical Officer, Los Angeles County + University of Southern California Medical Center CME Credit Available for all Providence Providers In order to claim CME credit, please click on the following link: https://forms.office.com/r/ZE5WEe6bfr (or copy & paste into your browser) Accreditation Statement: Providence Oregon Region designates this enduring material activity for a maximum of 1.0 AMA PRA Category 1  creditTM. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Providence Oregon Region is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians. Planning Committee & Faculty Disclosure: The Planning Committee and faculty have no relevant financial relationships with ineligible companies interests to disclose. Original Date: September 27, 2022 End Date: September 27, 2023

Brad Spellberg, MD, FIDSA, FACP, Chief Medical Officer, Los Angeles County + University of Southern California Medical Center CME Credit Available for all Providence Providers In order to claim CME credit, please click on the following link: https://forms.office.com/r/ZE5WEe6bfr (or copy & paste into your browser) Accreditation Statement: Providence Oregon Region designates this enduring material activity for a maximum of 1.0 AMA PRA Category 1  creditTM. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Providence Oregon Region is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians. Planning Committee & Faculty Disclosure: The Planning Committee and faculty have no relevant financial relationships with ineligible companies interests to disclose. Original Date: September 27, 2022 End Date: September 27, 2023

Show notes at pharmacyjoe.com/episode706. In this episode, I'll discuss whether gram stain-guided initial antibiotic therapy for VAP is better than guideline recommended therapy. The post 706: Is gram stain-guided initial antibiotic therapy for VAP better than guideline recommended therapy? appeared first on Pharmacy Joe.

Show notes at pharmacyjoe.com/episode706. In this episode, I ll discuss whether gram stain guided initial antibiotic therapy for VAP is better than guideline recommended therapy. The post 706: Is gram stain guided initial antibiotic therapy for VAP better than guideline recommended therapy? appeared first on Pharmacy Joe.

In unserer 6. Folge besprechen wir die Ergebnisse der APPAC-Studie. Außerdem thematisieren wir Teile der im letzten Jahr erschienenen S1-Leitlinie zur Appendizitis des Erwachsenen. Salminen, P., et al., Five-Year Follow-up of Antibiotic Therapy for Uncomplicated Acute Appendicitis in the APPAC Randomized Clinical Trial. JAMA, 2018. 320(12): p. 1259-1265.

Comprehensive, relevant and insightful conversations about health and medicine happen here… on MedStar Health Doc Talk.    …real conversations with physician experts from around the largest healthcare system in the Maryland-DC region.They say that time heals all wounds.  But does it?  For some people getting a wound to heal suffer months without change.  Why?  What are the risks of that, and what is happening in technology and wound care to get patients healed and back to their lives? To answer those questions and more about healing wounds, we are talking with Dr. David Zachary Martin, regional medical director of the MedStar Health Wound Healing Institute in Baltimore.

Recent studies have suggested that a short course of antibiotics, compared to longer durations, are just as efficacious for many common infections. The appropriate duration of urinary tract infections for men, by definition complicated, is uncertain due to the risk of developing secondary prostatitis. A new study evaluates 7 vs 14 days of antibiotic treatment of UTIs in men without fever.Redeem your CPE or CME credit here! References and resources: Drekonja DM, Trautner B, Amundson C, Kuskowski M, Johnson JR. Effect of 7 vs 14 Days of Antibiotic Therapy on Resolution of Symptoms Among Afebrile Men With Urinary Tract Infection: A Randomized Clinical Trial. JAMA. 2021;326(4):324–331. doi:10.1001/jama.2021.9899Continuing Education Information:Learning Objectives: 1. Describe the potential complications of urinary tract infections in men that are different than women2. Implement the findings of this study into a clinical practice0.05 CEU | 0.5 HrsACPE UAN: 0107-0000-21-316-H01-PInitial release date: 9/14/21Expiration date: 9/14/22Complete CPE & CME details can be found here!

Dr. Ebell and Dr. Wilkes discuss the POEM titled ' Five days of antibiotic therapy is comparable with 10 days in children with community-acquired pneumonia (SAFER) '

Dr. Ebell and Dr. Wilkes discuss the POEM titled ' Antibiotic therapy does not prevent death or acute exacerbations in adults with idiopathic pulmonary fibrosis '

Show note at pharmacyjoe.com/episode610 . In this episode, I ll discuss what phenotype of patients are most affected by delays in antibiotic therapy. The post 610: What subphenotype of patients are most affected by delays in antibiotic therapy? appeared first on Pharmacy Joe.

Drs. Andrew Heller and Marisa Brunetti welcome 2 special guests - Drs. Chaundra Schofield and Amy Lloyd - to discuss treating common bacterial infections using antibiotics. Article referenced in the show: https://www.sciencedirect.com/science/article/pii/S109002331830460X?via%3Dihub

Vitals & Useful Links: Learn about an important etiology of abdominal pain. See spoilers below if you want to know which one. Podcast: Approach to Abdominal Pain - EM Clerkship Podcast and Nausea and Vomiting - EM Clerkship Podcast Clinical Reference: ACEP Clinical Guidelines on This Episode's Topic (*SPOILER ALERT*) This week we welcome a new host, Jordan, who has the honor of being EMJC's first MD on the podcast and brings us back to some EM basics. Jordan is an EM intern who joins us to lead Kyle (MS4) and Arman (MS4) through a case of a young woman with nausea, vomiting, and abdominal pain. How would you approach this case? As always, we learn a couple very important points about evaluating and treating abdominal pain, nausea, and vomiting. If you have any questions, concerns, or comments, please email us at emjccast@gmail.com. *EPISODE SPOILERS BELOW* Jordan's Article on Antibiotic Therapy for Acute Appendicitis Salminen, P., Tuominen, R., Paajanen, H., Rautio, T., Nordström, P., Aarnio, M., ... & Virtanen, J. (2018). Five-year follow-up of antibiotic therapy for uncomplicated acute appendicitis in the APPAC randomized clinical trial. Jama, 320(12), 1259-1265. Surviving Sepsis Campaign Rhodes, A., Evans, L. E., Alhazzani, W., Levy, M. M., Antonelli, M., Ferrer, R., ... & Rochwerg, B. (2017). Surviving sepsis campaign: international guidelines for management of sepsis and septic shock: 2016. Intensive care medicine, 43(3), 304-377. DISCLAIMER: The views/opinions expressed in this podcast are that of the hosts/guests and do not reflect their respective institutions. This is NOT a medical advice podcast, if you are having a medical emergency you should call 911 and get help. This is an educational podcast, and as such, sometimes we get things wrong - if you notice this, please email us at emjccast@gmail.com. Intro Music: "Walk Through the Park" by Track Tribe

Paper for discussion: Quality of Life and Patient Satisfaction at 7-Year Follow-up of Antibiotic Therapy vs Appendectomy for Uncomplicated Acute Appendicitis: A Secondary Analysis of a Randomized Clinical Trial. Our tune is"Inspiring Optimistic Upbeat Energetic Guitar Rhythm" by Free Music | https://soundcloud.com/fm_freemusic Music promoted by https://www.free-stock-music.com Creative Commons Attribution 3.0 Unported License https://creativecommons.org/licenses/by/3.0/deed.en_US Teaching topic: Clinical Research, Types of Studies and Designs.

Today we had the pleasure of talking to Dr. Barbara Jones, first author on a new paper in JAMA IM about the outcomes in veterans treated with empirical anti-MRSA therapy vs standard therapy. She gives us a master class in propensity weighted analysis and instrumental variable analysis. We also look at whether outcomes are different in patients who are cared for by hospitalists who call more consults than their colleagues, and how much money we could save with a single payer system in the United States. Empirical Anti-MRSA vs Standard Antibiotic Therapy in Pneumonia High Consulting Hospitalists and Patient OutcomesMedicare for All in the USMusic from https://filmmusic.io"Sneaky Snitch" by Kevin MacLeod (https://incompetech.com)License: CC BY (http://creativecommons.org/licenses/by/4.0/)

Interview with Paulina Salminen, MD, PhD, and Suvi Sippola, MD, authors of Quality of Life and Patient Satisfaction at 7-Year Follow-up of Antibiotic Therapy vs Appendectomy for Uncomplicated Acute Appendicitis: A Secondary Analysis of a Randomized Clinical Trial

Interview with Paulina Salminen, MD, PhD, and Suvi Sippola, MD, authors of Quality of Life and Patient Satisfaction at 7-Year Follow-up of Antibiotic Therapy vs Appendectomy for Uncomplicated Acute Appendicitis: A Secondary Analysis of a Randomized Clinical Trial

In this episode, guest host Dr. David Poetker speaks with Dr. Alex Chiu. They will discuss the article: Topical antibiotic therapy in chronic rhinosinusitis: an update. Read the article in International Forum of Allergy and Rhinology Listen and subscribe for free on Apple Podcasts , Google Play Music and Subscribe on Android.

Critically ill patients are at high risk for developing a life-threatening infection such as bloodstream infection or pneumonia. These infections might lead to sepsis and multiple organ failure. Adequate antimicrobial therapy is essential to optimize the chances of survival. Three key issues in this regard are (i) a first antimicrobial dose administered as soon as possible after the onset of the septic episode, (ii) an empiric antimicrobial spectrum covering the causative pathogens, and (iii) adequate dosing. However, efficient dosing is problematic because of pathophysiological changes associated with critical illness affects the pharmacokinetics of mainly hydrophilic antimicrobials. And the preparation and administration of antibiotics may also negatively impact the efficiency of therapy. Therefore nurses must be aware of some points of interest in order to optimize antibiotic therapy.

Author:  Aaron Lessen, MD Educational Pearls:   5-year follow up study on antibiotic treatment for uncomplicated appendicitis showed 39.1% recurrence rate requiring appendectomy by 5 years Nearly 60% chance then of preventing an appendectomy by using antibiotics only for uncomplicated appendicitis   Editor’s note: not surprisingly, complications were much higher in the group receiving surgery, which reiterates why an antibiotic-only approach is attractive for the right patient population References: Salminen P, Tuominen R, Paajanen H, Rautio T, Nordström P, Aarnio M, Rantanen T, Hurme S, Mecklin JP, Sand J, Virtanen J, Jartti A, Grönroos JM. Five-Year Follow-up of Antibiotic Therapy for Uncomplicated Acute Appendicitis in the APPAC Randomized Clinical Trial. JAMA. 2018 Sep 25;320(12):1259-1265. doi: 10.1001/jama.2018.13201. PubMed PMID: 30264120. Summary by Travis Barlock, MS4    |   Edited by Erik Verzemnieks, MD  

In 2015, JAMA published results of a randomized clinical trial showing that antibiotic treatment for acute appendicitis was feasible. Doubters of the efficacy of antibiotics for treating appendicitis were concerned about what the long-term recurrence rate would be for those patients treated without surgery. The 5-year results of the study are now presented, showing that only about 40% of patients treated with antibiotics ultimately go on to have an appendectomy. Read the article: Five-Year Follow-up of Antibiotic Therapy for Uncomplicated Acute Appendicitis in the APPAC Randomized Clinical Trial

Show notes at pharmacyjoe.com/episode317. The post 317: Assessing response to antibiotic therapy in community acquired pneumonia appeared first on Pharmacy Joe.

Dr. Fraser, MD, speaks with Jean Baptiste Lascarrou, MD, about the article, Antibiotic Therapy in Comatose Mechanically Ventilated Patients Following Aspiration: Differentiating Pneumonia from Pneumonitis, published in Critical Care Medicine.

Dr. Fraser, MD, speaks with Jean Baptiste Lascarrou, MD, about the article, Antibiotic Therapy in Comatose Mechanically Ventilated Patients Following Aspiration: Differentiating Pneumonia from Pneumonitis, published in Critical Care Medicine.

Optimizing Your Functional Medicine Gut Program - Dr. J Live Podcast #164 Get Show Updates Here: http://www.beyondwellnessradio.com/newsletter You-tube Podcast Subscribe: http://www.youtube.com/subscription_center?add_user=justinhealth Show Transcription: https://justinhealth.com/optimizing-your-functional-medicine-gut-program-live-podcast-164/ In today's video, Dr. Justin Marchegiani and Evan Brand discuss the topic of creating a functional medicine toolbox for your gut health. Learn about the natural ways to modify your diet, improve your digestion, and promote your overall gut health. Watch and listen as they reveal some of the tools in the trade. Discover some protocols that help aid problems with gut fungus, yeast overgrowth and infection, gut bacteria issues and parasites in your digestive system. Learn about the different steps to take on how to ensure you're taking the right path for better gut health. Also, stay tuned for more information about how to further catch some knowledge bombs from this functional medicine duo. In this episode, we cover: 03:30   Looking at the Food 04:23   Digestive Support 06:10   Silver in the Killing Phase 09:47   Probiotics and Antibiotic Therapy 13:48   Retest Subscribe on I-Tunes: http://www.beyondwellnessradio.com/itunes Review us at: http://www.beyondwellnessradio.com/itunes Visit us at: http://www.beyondwellnessradio.com Have a question: http://www.beyondwellnessradio.com/question

Bugs, drugs, and optimal duration for antibiotic therapy? New frontiers in HIV treatment? Listen this week as Kieran and Jay Spiegel, a resident in General Internal Medicine in Toronto, discuss two studies: It's hard to remember what the right drug is to treat a certain bug, let alone the correct duration of therapy. Further, for ... The post REPLAY: Bugs & Drugs – Duration of Antibiotic Therapy in Community-Acquired Pneumonia and Early Antiretroviral Treatment for HIV appeared first on Healthy Debate.

Bugs, drugs, and optimal duration for antibiotic therapy? New frontiers in HIV treatment? Listen this week as Kieran and Jay Spiegel, a resident in General Internal Medicine in Toronto, discuss two studies: It's hard to remember what the right drug is to treat a certain bug, let alone the correct duration of therapy. Further, for ...The post REPLAY: Bugs & Drugs – Duration of Antibiotic Therapy in Community-Acquired Pneumonia and Early Antiretroviral Treatment for HIV appeared first on Healthy Debate.

  Bugs, drugs, and optimal duration for antibiotic therapy? New frontiers in HIV treatment? Listen this week as Kieran and Jay Spiegel, a resident in General Internal Medicine in Toronto, discuss two studies: It's hard to remember what the right drug is to treat a certain bug, let alone the correct duration of therapy. Further, ...The post Bugs & Drugs – Duration of Antibiotic Therapy in Community-Acquired Pneumonia and Early Antiretroviral Treatment for HIV appeared first on Healthy Debate.

  Bugs, drugs, and optimal duration for antibiotic therapy? New frontiers in HIV treatment? Listen this week as Kieran and Jay Spiegel, a resident in General Internal Medicine in Toronto, discuss two studies: It's hard to remember what the right drug is to treat a certain bug, let alone the correct duration of therapy. Further, ... The post Bugs & Drugs – Duration of Antibiotic Therapy in Community-Acquired Pneumonia and Early Antiretroviral Treatment for HIV appeared first on Healthy Debate.

Volume 6, Issue 6.Daniel Heintz, MD and Karen McCoy, MD cover the important topic of Trends in Inhaled Antibiotic Therapy in the format of case-study scenarios for the clinical practice.Take our post-test to claim CME credits:Physician post-testNurse post-testTo read a companion newsletter click here.The post Trends in Inhaled Antibiotic Therapy appeared first on DKBmed Radio. Hosted on Acast. See acast.com/privacy for more information.

Michael S. Weinstein, MD, FACS, FCCM, speaks with Zachariah Thomas, PharmD, about the article, A Multicenter Evaluation of Prolonged Empiric Antibiotic Therapy in Adult ICUs in the United States, published in Critical Care Medicine.

Michael S. Weinstein, MD, FACS, FCCM, speaks with Zachariah Thomas, PharmD, about the article, A Multicenter Evaluation of Prolonged Empiric Antibiotic Therapy in Adult ICUs in the United States, published in Critical Care Medicine.

Community acquired pneumonia accounts for 600,000 hospital admissions a year. Many patients with this disease are quite ill and have a very high mortality. To save lives, the appropriate antibiotics should be given in a timely basis, but it is not clear what the best antibiotics are and how long they should be given. In this podcast we interview the author of a JAMA review on community acquired pneumonia, Dr Jonathan Lee, author of Antibiotic Therapy for Adults Hospitalized With Community-Acquired Pneumonia, who performed a systematic review of the literature to determine the best way to treat community acquired pneumonia.

Community acquired pneumonia accounts for 600,000 hospital admissions a year. Many patients with this disease are quite ill and have a very high mortality. To save lives, the appropriate antibiotics should be given in a timely basis, but it is not clear what the best antibiotics are and how long they should be given. In this podcast we interview the author of a JAMA review on community acquired pneumonia, Dr Jonathan Lee, author of Antibiotic Therapy for Adults Hospitalized With Community-Acquired Pneumonia, who performed a systematic review of the literature to determine the best way to treat community acquired pneumonia.

Appendicitis is one of the most common reasons people undergo abdominal surgery. Lost in history are the reasons why appendectomy was performed in the first place, and in the hundred years since appendicitis was first described, many changes in patient management have occurred improving both the diagnosis and treatments for appendicits. A major trial, Antibiotic Therapy vs Appendectomy for Treatment of Uncomplicated Acute Appendicitis, was recently published in JAMA showing that most patients with acute, uncomplicated appendicitis can be treated with antibiotics alone and avoid surgery.

Community-acquired pneumonia (CAP) remains a force to reckon with, as it accounts for 1.1 million of all deaths in children less than 5 years of age globally, with disproportionately higher mortality occurring in the low and middle income-countries (LMICs) of Southeast Asia and Africa. Existing strategies to curb pneumonia-related morbidity and mortality have not effectively translated into meaningful control of pneumonia-related burden. A recent systematic review in ADC looks at trials conducted in LMICs to determine the most suitable antibiotic therapy for treating pneumonia (very severe, severe and non-severe). ADC global health commissioning editor Nick Brown talks to one of the authors, Rehana Salam, Division of Women and Child Health, The Aga Khan University, Karachi, Pakistan, to hear what they found.Read the paper: http://goo.gl/ZCw0Rr

Today we are lucky to have Dr. Manjari Joshi, Associate Professor of Medicine, Division of Infectious Diseases at both the University of Maryland SOM and the R Adams Cowley Shock Trauma Center. For today’s lecture, Dr. Joshi will take us through the chaotic world of antibiotic use in critical care patients. She will show us ...

Recognizing osteomyelitis can be challenging. Treating it doesn’t have to be – especially in the Pediatric ED. This edition of PEM Currents reviews the current evidence surrounding the initial choice of antibiotic, monitoring treatment response and overall therapeutic duration. 

Editor's Audio Summary by Phil B. Fontanarosa, MD, MBA, Executive Editor, the Journal of the American Medical Association, for the March 27, 2013 issue

Role of Procalcitonin in Guiding Antibiotic Therapy Author Tasadaq Fazili discusses with Pamela Hsieh, Assistant Editor for AJHP, current clinical use of procalcitonin in guiding antibiotic therapy as well as future areas of research. The article under discussion appears in the December 1, 2012, issue of AJHP. For more information visit www.ajhp.org.

This podcast highlights original research appearing in the December 2011 edition of Otolaryngology - Head and Neck Surgery, the official journal of the American Academy of Otolaryngology - Head and Neck Surgery (AAO-HNS) Foundation. Editor in chief Richard M. Rosenfeld, MD, MPH, is joined by lead author Inessa Fishman, MD, and associate editor Peter Roland, MD, for an informative and clinically relevant discussion of managing tympanostomy tube otorrhea that is refractory to oral or topical antibiotics. Click here to read the full article.