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How much do our genes determine about our lives, and could they influence traits like risk-taking, antisocial behaviour or even violence? Ian Sample talks to Kathryn Paige Harden, a behavioural geneticist and professor of psychology at the University of Texas at Austin who studies how genetic factors shape human behaviour. In her book Original Sin she explores how nature and nurture combine to influence our likelihood of committing crimes, and asks whether the ‘cause' of our actions matters for how we think about culpability. Help support our independent journalism at theguardian.com/sciencepod
Met Office forecasters have issued a rare red weather warning for England, with temperatures potentially reaching 40C (104F) in some places. Europe is also dealing with a debilitating heatwave, with schools closed, trains cancelled and France even restricting the consumption of alcohol outdoors to take pressure off the emergency services. The high temperatures coincide with the coming El Niño, which some scientists have nicknamed Godzilla for its predicted strength. To find out whether the two are linked, Ian Sample hears from our Europe climate correspondent, Ajit Niranjan. He explains why it's so hot, why we could be in for even worse and how we can keep as cool as possible. Help support our independent journalism at theguardian.com/sciencepod
The UK prime minister, Keir Starmer, has announced a social media ban for under-16s, as part of an online safety drive that aims to go even further than the world's first ban, introduced by Australia last year. Many parents have welcomed the proposals, but scientists have pointed to the lack of strong evidence for the efficacy of bans, and some campaigners have argued that the proposal allows social media companies to avoid making meaningful changes on their platforms. Ian Sample is joined by co-host Madeleine Finlay to explore what the evidence indicates about the harms of social media and the impact of banning it outright. Help support our independent journalism at theguardian.com/sciencepod
It's just a week until the first whistle of the 2026 World Cup. To celebrate, Madeleine Finlay sits down with Ian Sample to discuss the science behind the tournament. It's set to be one of the hottest World Cups on record and a group of scientists has written to Fifa asking them to reconsider their heat mitigations for players and referees. Dr Oliver Gibson of Brunel University outlines their concerns. Also on the agenda is the huge fossil fuel impact of this tournament, and the impact of VAR on the psychology of referees, and fans. Help support our independent journalism at theguardian.com/footballweeklypod. Watch us on YouTube: https://www.youtube.com/@FootballWeeklyPodcast
It's just a week until the first whistle of the 2026 World Cup. To mark the occasion, Madeleine Finlay talks to Ian Sample about the science behind the tournament. It's likely to be one of the hottest ever World Cups, and scientists have written to Fifa asking it to reconsider its heat mitigations for players and referees. Dr Oliver Gibson of Brunel University outlines their concerns. Also on the agenda is the huge fossil-fuel impact of the tournament, and the effect of VAR on the psychology of referees and fans. Help support our independent journalism at theguardian.com/sciencepod
Humans have been wondering why we sleep for thousands of years. Is sleep's purpose rest and relaxation, memory consolidation or maybe cognitive processing? In the last 15 years, scientists have discovered another possible explanation – waste disposal. In 2012 neuroscientist Maiken Nedergaard's lab discovered that the brain has its own cleaning process, the glymphatic system, which clears away unhelpful proteins and metabolic byproducts, and only switches on at night. Since that groundbreaking discovery we've learned more about what drives this system and, importantly, how it could be impacting dementia. To understand more, Ian Sample talks to Prof Nedergaard about how she made the original discovery and how subsequent work is building a picture of sleep as anything but a quiet and inactive state. Help support our independent journalism at theguardian.com/sciencepod
Last month at Beijing's half marathon, a robot named Lightning beat the human world record by nearly seven minutes. It's the latest in a string of AI-powered milestones that have got people wondering whether robots are about to enter our everyday lives, just as chatbots have. And the country leading the charge is China, where the government has pledged to invest more than £100bn in robotics over the next 20 years. To find out how robots are already entering the workforce, and what needs to happen to get them cleaning our homes and weeding our gardens, Ian Sample hears from the Guardian's senior China correspondent, Amy Hawkins, and from Nathan Lepora, professor of robotics and AI at Bristol University, who researches how robots can achieve human-like dexterity. Help support our independent journalism at theguardian.com/sciencepod
Home red-light therapy devices have exploded in popularity as masks, body wraps and mittens promise to reduce wrinkles, redness and even acne. But do the claims stack up, and what other benefits are scientists investigating? Ian Sample hears from his co-host, Madeleine Finlay, and the consultant dermatologist Dr Jonathan Kentley. Kentley explains how the potential benefits of red light were discovered, how it is thought to interact with collagen in our skin, and what science has to say about its impact on our appearance. Help support our independent journalism at theguardian.com/sciencepod
An outbreak of Ebola has emerged in the Democratic Republic of Congo and Uganda, leading to nearly 400 confirmed cases and more than 100 deaths. To find out how the outbreak might have begun, what authorities can do to contain it and why this outbreak is causing particular concern, Ian Sample hears from Daniela Manno, a clinical epidemiologist at the London School of Hygiene and Tropical Medicine. Help support our independent journalism at theguardian.com/sciencepod
Madeleine Finlay sits down with co-host and science editor Ian Sample to discuss three eyecatching stories from the week, including an update on hantavirus. Also on the agenda is the Pentagon's release of a tranche of never before seen documents relating to UFOs, and a study looking at the link between taking part in cultural activities and slower biological ageing. Help support our independent journalism at theguardian.com/sciencepod
Madeleine Finlay sits down with co-host and Guardian science editor Ian Sample to talk through three eye-catching stories from the week, including the news that the number of years people in the UK are spending in good health has declined compared with a decade ago. Also on the agenda is the science, tech and nutrition behind two runners at this weekend's London marathon breaking the two-hour threshold, and an answer to why some old houses feel particularly spooky. Help support our independent journalism at theguardian.com/sciencepod
Madeleine Finlay sits down with science editor Ian Sample to hear about some of the winners of the Breakthrough Prize, which held its ceremony in LA last weekend. Each prize is worth $3m and they're awarded in physics, maths and life sciences. Madeleine and Ian hear from molecular biologist Jean Bennett, who shared a life sciences prize for her work developing the world's first FDA-approved gene augmented therapy for sight loss. She explains how a chance encounter while dissecting a brain in medical school led her on a 25-year journey to develop the treatment.. Help support our independent journalism at theguardian.com/sciencepod
Earlier this month the AI company Anthropic said it had created a model so powerful that, out of a sense of responsibility, it was not going to release it to the public. Anthropic says the model, Mythos Preview, excels at spotting and exploiting vulnerabilities in software, and could pose a severe risk to economies, public safety and national security. But is this the whole story? Some experts have expressed scepticism about the extent of the model's capabilities. Ian Sample hears from Aisha Down, a reporter covering artificial intelligence for the Guardian, to find what the decision to limit access to Mythos reveals about Anthropic's strategy, and whether the model might finally spur more regulation of the industry.. Help support our independent journalism at theguardian.com/sciencepod
Madeleine Finlay sits down with co-host and science editor Ian Sample to discuss three eye-catching stories from the week, including a review into the effectiveness of a new class of Alzheimer's drug that was once hailed as a game-changer in slowing the progress of the disease. Also on the agenda is the news that the world could be heading for a ‘super El Niño' this summer and a study exploring whether conversations about dull topics really are as boring as we expect them to be. Help support our independent journalism at theguardian.com/sciencepod
Alongside the oil and gas stranded in the strait of Hormuz is another commodity vital to today's economy: helium. It is a critical element in all kinds of areas from MRI machines to the Large Hadron Collider, and even deep-sea diving. It is also integral to the AI boom. And this isn't the first time its fragile global supply chain has been threatened. So why is helium so useful, and what will happen if the shortage continues? Ian Sample hears from co-host Madeleine Finlay, and from Sophia Hayes, professor of chemistry at Washington University in St. Louis. Help support our independent journalism at theguardian.com/sciencepod
This week Artemis II's four-astronaut crew broke Apollo 13's distance record, becoming the humans to travel the farthest from Earth. Now on their way home, the team has experienced tech malfunctions, views like no other and moments of intense emotion, all in under 10 days. To find out about all the highs and lows of the mission, Madeleine Finlay hears from the Guardian's science editor, Ian Sample. Help support our independent journalism at theguardian.com/sciencepod
The number of human cases of guinea worm, a painful and debilitating tropical illness, fell to a record low of just 10 last year, according to the Carter Centre, the foundation set up by the late former US president Jimmy Carter. But despite years-long declines, it remains almost impossible to completely eradicate the parasite. Only one human illness has been entirely eradicated: smallpox. Why is it so difficult, and could guinea worm one day be the second? Ian Sample hears from co-host Madeleine Finlay, and David Molyneux, emeritus professor of tropical disease microbiology at the Liverpool School of Tropical Medicine. Help support our independent journalism at theguardian.com/sciencepod
Saunas and cold plunge pools are popping up everywhere in the UK, bringing fiery heat and icy cold to a beach, city farm or park near you. Their users will be ready with all the reasons why it's good for both the mind and the body. But what's the evidence for the benefits of sauna and cold plunge? Madeleine Finlay hears from Ian Sample and from Dr Heather Massey, associate professor at the University of Portsmouth's extreme environments laboratory.. Help support our independent journalism at theguardian.com/sciencepod
If all goes to plan, Artemis II, Nasa's mission to return humans to the moon, will launch this week. The mission will mark the farthest that humans have travelled from Earth, and the first return to the moon in more than 50 years. It will also pave the way for landing on the moon again as soon as 2028. But given the Apollo missions have already achieved that feat, does going back to the moon still matter today? To find out, Madeleine Finlay hears from the Guardian's science editor, Ian Sample, the Atlantic journalist Ross Andersen, and Jan Wörner, a former director general of the European Space Agency. Help support our independent journalism at theguardian.com/sciencepod
A box the size of a filing cabinet was lifted by crane, slowly moved and placed very carefully in the back of an unassuming lorry earlier this week. What looked like a casual drive around the Cern campus was actually a world-first experiment in transporting antimatter, the most expensive and volatile substance on Earth. To find out why scientists wanted to achieve this milestone, and what happened on the journey, Madeleine Finlay hears from the Guardian's science editor, Ian Sample, and the Cern physicist Dr Christian Smorra.. Help support our independent journalism at theguardian.com/sciencepod
Why is it like something to be ourselves and how do physical processes create our subjective experience? These questions get to the heart of the knotty problem of consciousness, and they provided the spark for the latest book from award-winning author and journalist Michael Pollan. In A World Appears, Pollan goes in search of answers about what we do and don't know about consciousness, and why it has proven such an elusive phenomenon. He tells Ian Sample how thoughts and feelings shape our conscious experience, whether we can learn anything about human consciousness from AI, and why he thinks our minds need to be defended in today's technology saturated world. Help support our independent journalism at theguardian.com/sciencepod
Among the many justifications Donald Trump has presented for the US and Israel attacking Iran has been the supposedly imminent threat posed by its nuclear weapons program. But how close was the country really to developing an atomic weapon? Ian Sample hears from Kelsey Davenport, the director of non-proliferation policy at the Arms Control Association. She sets out why many experts don't believe the country even had a structured nuclear weapons program and explains what she thinks the impact of the war could be on nuclear proliferation around the world
The Guardian's science editor, Ian Sample, talks to Madeleine Finlay about three eye-catching science stories from the week, including a study that explores the link between exercise and brain health. Also on the agenda: the discovery that hedgehogs can hear high-frequency ultrasound and what this could mean for their conservation, and new research examining how biased AI autocomplete tools can influence the beliefs of users.. Help support our independent journalism at theguardian.com/sciencepod
Among the many justifications Donald Trump has presented for the US and Israel attacking Iran has been the supposedly imminent threat posed by its nuclear weapons programme. But how close was the country really to developing an atomic weapon? Ian Sample hears from Kelsey Davenport, the director of non-proliferation policy at the Arms Control Association. She sets out why many experts don't believe the country even had a structured nuclear weapons programme, and explains what she thinks the impact of the war could be on nuclear proliferation around the world.. Help support our independent journalism at theguardian.com/sciencepod
For a long time fat was seen simply as an inert yellow substance wrapping around our bodies, but now that's changing. Scientists are beginning to understand that our fat is actually intricate and dynamic, constantly in conversation with the rest of the body. It's now even considered by some to be an organ in its own right. To find out more about the complex role fat plays in our health, Ian Sample hears from co-host Madeleine Finlay and from Declan O'Regan, professor of cardiovascular AI at Imperial College London. Help support our independent journalism at theguardian.com/sciencepod
Madeleine Finlay sits down with science editor Ian Sample and science correspondent Nicola Davis to discuss three eye-catching stories, including the impact of a powerful psychedelic on depression, answers on the death of Russian opposition leader Alexei Navalny, and an explanation to the mystery of why humans have chins. Help support our independent journalism at theguardian.com/sciencepod
Testimonials about the beneficial health effects of magnesium supplements abound online, with influencers claiming that a daily pill can help with everything from anxiety to sleep and brain fog. But do any of these claims stack up? Ian Sample is joined by co-host Madeleine Finlay to find out where the science stands. They also hear from Katherine Tucker, the founder of the Center for Population Health at the University of Massachusetts Lowell. She explains what magnesium is doing in our bodies and the best approach we can take to ensure we are getting enough. Help support our independent journalism at theguardian.com/sciencepod
The release of the latest batch of documents relating to the late child sex offender Jeffrey Epstein has shed further light on his close relationship with the world of science. To find out why he cultivated scientists and where his interests lay, Ian Sample hears from Dan Vergano, a senior editor at Scientific American.. Help support our independent journalism at theguardian.com/sciencepod
The Guardian's science editor, Ian Sample, talks to Madeleine Finlay about three eye-catching science stories from the week, including a study that suggests positive thinking can boost immune response. Also on the agenda is the mysterious rise of scabies in the UK, and the discovery that cows are more adept with tools than previously known. Help support our independent journalism at theguardian.com/sciencepod
Studies detecting microplastics throughout human bodies have made for alarming reading in recent years. But last week, the Guardian's environment editor, Damian Carrington, reported on major doubts among a group of scientists about how some of this research has been conducted. Damian tells Ian Sample how he first heard about the concerns, why the scientists think the discoveries are probably the result of contamination and false positives, and where it leaves the field. He also reflects on how we should now think about our exposure to microplastics. Help support our independent journalism at theguardian.com/sciencepod
Ian Sample puts listeners' questions on dreams and nightmares to Dr Michelle Carr, director of the Dream Engineering Laboratory in Montreal's Centre for Advanced Research in Sleep Medicine, and author of the new book Into the Dream Lab. They look at why we dream, what we can learn by examining our dreams, and what we can do when dreams turn to nightmares. Dr Carr gives her top tips for taking charge of our dreams and trying to influence their content. Help support our independent journalism at theguardian.com/sciencepod
Ian Sample puts listeners' questions on sleep to Dr Allie Hare, consultant physician in respiratory and sleep medicine at Guy's and St Thomas' hospitals and president of the British Sleep Society. They cover why women experience sleep disturbance during the menopause, why sleep paralysis affects some people more than others, and what scientists know about the link between sleep and dementia. Hare also gives her top tips for getting better sleep in 2026. Help support our independent journalism at theguardian.com/sciencepod
Last year was full of unexpected science news, from the discovery of a new colour, to the interstellar visitor 3I/Atlas passing by our solar system, and a world-first treatment with a personalised gene editing therapy. So what will this year bring? Ian Sample and science correspondent Hannah Devlin discuss the big stories likely to hit the headlines and share their predictions for 2026. Help support our independent journalism at theguardian.com/sciencepod
The US capture of Nicolás Maduro and his wife, Cilia Flores, on Saturday left many people wondering why? Donald Trump hinted at an answer when he claimed the Venezuelan regime had stolen US oil rights and that American oil companies would help to run Venezuela going forward. Jillian Ambrose, the Guardian energy correspondent, explains to Ian Sample the appeal of Venezuelan oil to the US, how easy it is to extract and what the latest action tells us about Trump's energy strategy. Help support our independent journalism at theguardian.com/sciencepod
Kevin Hall spent 21 years at the US National Institutes of Health and became known globally for his pioneering work on ultra-processed foods. In April he unexpectedly took early retirement, citing censorship under the Trump administration. Now he has co-authored a book with the journalist Julia Belluz that aims to bust myths and challenge wellness orthodoxy on everything from weight loss and metabolism to supplements and wearables. In this episode from October, Hall tells Ian Sample what he wants us all to understand about diet, exercise and weight loss, and what led to his departure from the job he loved. Help support our independent journalism at theguardian.com/sciencepod
More of us are turning to products containing mushroom extracts, with the medicinal fungi market worth billions of pounds. Promises of mental and physical health benefits have seen its popularity spill over from wellness influencers to the shelves of Marks & Spencer – but is there any scientific evidence behind these claims? In this episode from June, Ian Sample chats to Madeleine Finlay about the appeal of mushroom drinks and supplements, and hears from the mycologist Prof Nik Money on what we really know about how fungi can affect our minds and bodies. Help support our independent journalism at theguardian.com/sciencepod
Scientists are beginning to understand that ageing is not simply a linear process and we age, according to recent research, in three accelerated bursts: at about 40, 60 and 80 years old. In this episode from July, Ian Sample talks to Stanford University's Prof Michael Snyder, who explains what the drivers of these bursts of ageing could be, and how they might be counteracted. Help support our independent journalism at theguardian.com/sciencepod
We all know eating too much sugar is bad for our health – but would we be better off replacing it with artificial sweetener? It's a question Science Weekly listener Marion posed recently and, as Madeleine Finlay tells Ian Sample, the answer is complicated. She explains what the science says about sugar v sweeteners with the help of Prof Havovi Chichger, from Anglia Ruskin University, and Prof Jim Krieger, from the University of Washington's school of public health. Help support our independent journalism at theguardian.com/sciencepod
The Guardian's science editor, Ian Sample, sits down with co-host Madeleine Finlay to discuss three eye-catching stories from the week, including a study investigating the link between social media use in children and rising rates of ADHD diagnosis. Also on the agenda is groundbreaking evidence that humans were starting fires 350,000 years earlier than previously known, and the discovery of a new strain of the mpox virus in England. Help support our independent journalism at theguardian.com/sciencepod
At this time of year when stress levels are high, we can find ourselves being sent over the edge by frustrating post office queues, infuriating traffic jams and tension-filled family occasions. But what's the best way to release our anger and find peace and calm this festive season? To find out, Ian Sample hears from science correspondent Nicola Davis, who recently tried out a rage room as a means of channelling her fury, and from Brad Bushman, professor of mass communication and psychology at Ohio State University. Is venting the most effective way to overcome anger, and if not, what is?. Help support our independent journalism at theguardian.com/sciencepod
Science editor Ian Sample sits down with co-host Madeleine Finlay and science correspondent Hannah Devlin to hear about three eye-catching stories from the week, including a study showing that the brain has five ‘eras', with adult mode not starting until our early 30s. Also on the agenda is new research showing the shingles vaccine not only protects against dementia but could actually slow its progress, and a paper exploring how ants sacrifice themselves when they become infected with pathogens to protect their healthy relatives. Help support our independent journalism at theguardian.com/sciencepod
Artificial intelligence can execute tasks in seconds that once took humans hours, if not days to complete. While this may be great for productivity, some researchers are concerned that our increasing use of AI could be impacting our ability to tackle difficult problems and think critically. To find out where the science stands, and how worried we should be about the potential of AI to change how we think, Ian Sample hears from Madeleine Finlay and Sam Gilbert, professor of neuroscience at University College London. Help support our independent journalism at theguardian.com/sciencepod
Patrick Vallance, the minister for science, research and innovation, recently unveiled a plan to cut animal testing through greater use of AI and other technologies, with the eventual aim of phasing it out altogether. To understand how this will affect research and what could be used in place of animal models, Madeleine Finlay hears from science editor Ian Sample, Prof Hazel Screen of Queen Mary University London and Prof Kevin Harrington from the Institute of Cancer Research. Help support our independent journalism at theguardian.com/sciencepod
This year's flu season has begun more than a month earlier than usual, with a mutated strain spreading widely among younger people and expected to drive a wave of hospital admissions as it reaches the elderly. Science editor Ian Sample speaks to Madeleine Finlay about what we know so far and Prof Ed Hutchinson of the University of Glasgow explains how people can best protect themselves and each other. Help support our independent journalism at theguardian.com/sciencepod
Ian Sample joins Madeleine Finlay to discuss some of the most intriguing science stories from the week. They discuss the complicated legacy of James Watson, who won the Nobel Prize for the discovery of the structure of DNA; a new breakthrough in the quest to understand the autoimmune disease lupus; and why everyone from Joe Rogan to Kim Kardashian is talking about comet 3I/Atlas.. Help support our independent journalism at theguardian.com/sciencepod
Do you have an uncanny recall for faces? Have you ever recognised the same extra in TV shows that are decades apart? If so you could be part of the small number of super recognisers. Research from the University of New South Wales indicates they naturally pick out the most useful parts of a given face to help commit it to memory. So what else have scientists uncovered about this elite cohort? Dr David Robertson, a senior lecturer in psychology at the University of Strathclyde, talks to Ian Sample about what life is like for super recognisers, and how their powers could be put to use for the public good. Help support our independent journalism at theguardian.com/sciencepod
This year's Nobel prizes in chemistry, physics and physiology or medicine have celebrated work that paves the way for the next generation of quantum technology, the creation of porous materials that have been compared to Hermione Granger's handbag and the discovery of the hidden army inside us that helps to keep our immune system in check. To find out more, Madeleine Finlay talks to our science editor, Ian Sample, and correspondents Nicola Davis and Hannah Devlin. Help support our independent journalism at theguardian.com/sciencepod
Kevin Hall spent 21 years at the US National Institutes of Health and became known globally for his pioneering work on ultra-processed foods. In April he unexpectedly took early retirement, citing censorship under the Trump administration. Now he has co-authored a book with the journalist Julia Belluz that aims to bust myths and challenge wellness orthodoxy on everything from weight loss and metabolism to supplements and wearables. Hall tells Ian Sample what he wants us all to understand about diet, exercise and weight loss, and what led to his departure from the job he loved. Help support our independent journalism at theguardian.com/sciencepod
The renowned primatologist Jane Goodall has died aged 91. She will be remembered for her observations that revolutionised our understanding of chimpanzees, as well as her tireless environmental advocacy. Ian Sample talks to the Guardian's global environment editor Jon Watts, who met Goodall several times, to find out what her scientific legacy will be. Help support our independent journalism at theguardian.com/sciencepod
Science editor Ian Sample talks through the dilemma facing more than a million people in the UK as the cost of the jabs jumps. Help support our independent journalism at theguardian.com/infocus