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3 episodes with natural products association npa
3 episodes with natural products association npa
2 episodes with natural products association npa
2 episodes with natural products association npa
2 episodes with natural products association npa
4 episodes with natural products association npa
2 episodes with natural products association npa
2 episodes with natural products association npa
2 episodes with natural products association npa
In this episode of The Natural View, Todd Pauli of 24 Stories Marketing and Maggie Jaqua of WholeFoods Magazine sit down with Kyle Turk, Director of Government Affairs at the Natural Products Association (NPA). Turk offers an update on one of the most pressing issues facing the industry right now: efforts to put age restrictions on certain supplements in the sports nutrition and weight loss categories. In New York, NPA filed litigation asserting that the state's dietary supplement prohibition is unconstitutional. Discussing the lawsuit, Turk stressed, "This is a critical lawsuit for us because if we don't win this we're gonna see places like California, New Jersey, Maryland, and some of these other more progressive states follow suit." Get the full story on the push to age-restrict certain supplements, plus: The negative implications for the industry and consumers. The importance of advocacy, and what role it is playing in this current fight. Specific calls to action for industry.
You should have the choice wether you want to supplement your health with natural supplements. It's really not a controversial statement. (Ex vitamin D, vitamin C, NMN, NAC, etc…)But without people like Daniel Fabricant, PhD., we would all be limited SEVERELY by what we could access without a prescription, or in many cases… ACCESS AT ALL!It doesn't end with supplements. The fight by the Natural Products Association (NPA) is one to liberate information and fair representation of clinical studies that fall outside the control of the massive pharmaceutical industry.Daniel Fabricant, Ph.D served as the Director of the Division of Dietary Supplement Programs at the U.S. Food and Drug Administration (FDA), where he directed agency policy, public affairs and regulatory action regarding regulation of the dietary supplement industry for more than three years.Today Dr. Fabricant is CEO and President of the NPA, the nation's largest and oldest trade organization
In this episode of The Natural View, Todd Pauli of 24 Stories Marketing and Maggie Jaqua of WholeFoods Magazine sit down with Daniel Fabricant, Ph.D., President and CEO of the Natural Products Association (NPA). Dr. Fabricant discusses: The most pressing issues facing the industry right now, and how is NPA working on behalf of the industry on these issues. The importance of advocacy, and positive outcomes that have stemmed from the industry's collective efforts. How NPA helps make it easier for industry members to get involved and play an active role in the future of the industry. Bright spots...and areas of concern...for 2024.
https://blog.priceplow.com/podcast/dan-fabricant-npa-2023-washington-dc For Episode 100 of the PricePlow Podcast, Ben and Mike flew to Washington D.C. for the Natural Products Association's annual DC Fly-In Day on June 7, 2023. Fly-in days, also known as “lobby days”, bring individuals together to advocate with legislators and other officials on behalf of their shared interests. So this was the day where members of the NPA could meet with their elected representatives on Capitol Hill to discuss matters of importance in terms of public policy geared towards the dietary supplement industry. Episode 100: Dan Fabricant of the NPA in Washington, DC It was only fitting, then, to schedule Episode 100 with Dan Fabricant, CEO of the Natural Products Association (NPA). This is the country's largest and oldest nonprofit organization dedicated to supporting the natural products industry — it was founded in 1936 and has over 700 members. In this podcast, we discuss why we should be involved in politics when it has become so off-putting the past decade or so, discuss what the FDA and industry both need to be doing better, and dig into this year's hot topics, which includes the battle against the FDA for NMN. The trip was spectacular — we'll include some videos at the bottom of this article. We were able to meet with congressmen and senators from New Jersey (Ben's district) and Oklahoma (Mike's home). Have a say — or someone else will do so for you The most major point to get across is this: If you're not talking to your legislators, then someone else is. There's only so much oxygen in DC, and every industry needs to fight for theirs. Now let's get into it: https://www.youtube.com/watch?v=QVhtNGUqfKI As a reminder, Dan was previously on the PricePlow Podcast in Episode #067, describing how the NPA fought Dick Durbin's 2022 Mandatory Product Listing Bill (described as “MPL” below). Ben had also joined in the fight in Trenton, NJ to prevent them from forcing stores to sell supplements from behind-the-counter (see coverage here and here on Instagram). These are both referenced below: Detailed Show Notes with Dan Fabricant of NPA (0:00) – Hot Start: We need to support our tribe (1:30) – Introduction and the Disenfranchisement with Politics (3:15) – We have to show up (4:30) – What is the NPA? (7:30) – Non-Profit 101 – How is NPA Run? (9:15) – Not Just Federal: Challenges in States (10:10) – Will uninformed legislators ever understand creatine?! (12:30) – Performance Supplements Lead the Way in this Industry (14:00) – Should the dietary supplement community discuss supplements for children (16:00) – The four pillars of the dietary supplement industry's regulatory framework (23:00) – Dan's Background at the FDA (24:00) – Dan vs. USPLabs (28:45) – What can be a dietary supplement? (32:30) – Botanicals and Constituents of Botanicals (35:15) – Foods and supplements cannot intoxicate (38:00) – New Dietary Ingredient Notifications (NDIN) (39:30) – Congress... Read more on the PricePlow Blog
https://blog.priceplow.com/podcast/dan-fabricant-npa-2023-washington-dc For Episode 100 of the PricePlow Podcast, Ben and Mike flew to Washington D.C. for the Natural Products Association's annual DC Fly-In Day on June 7, 2023. Fly-in days, also known as “lobby days”, bring individuals together to advocate with legislators and other officials on behalf of their shared interests. So this was the day where members of the NPA could meet with their elected representatives on Capitol Hill to discuss matters of importance in terms of public policy geared towards the dietary supplement industry. Episode 100: Dan Fabricant of the NPA in Washington, DC It was only fitting, then, to schedule Episode 100 with Dan Fabricant, CEO of the Natural Products Association (NPA). This is the country's largest and oldest nonprofit organization dedicated to supporting the natural products industry — it was founded in 1936 and has over 700 members. In this podcast, we discuss why we should be involved in politics when it has become so off-putting the past decade or so, discuss what the FDA and industry both need to be doing better, and dig into this year's hot topics, which includes the battle against the FDA for NMN. The trip was spectacular — we'll include some videos at the bottom of this article. We were able to meet with congressmen and senators from New Jersey (Ben's district) and Oklahoma (Mike's home). Have a say — or someone else will do so for you The most major point to get across is this: If you're not talking to your legislators, then someone else is. There's only so much oxygen in DC, and every industry needs to fight for theirs. Now let's get into it: https://www.youtube.com/watch?v=QVhtNGUqfKI As a reminder, Dan was previously on the PricePlow Podcast in Episode #067, describing how the NPA fought Dick Durbin's 2022 Mandatory Product Listing Bill (described as “MPL” below). Ben had also joined in the fight in Trenton, NJ to prevent them from forcing stores to sell supplements from behind-the-counter (see coverage here and here on Instagram). These are both referenced below: Detailed Show Notes with Dan Fabricant of NPA (0:00) – Hot Start: We need to support our tribe (1:30) – Introduction and the Disenfranchisement with Politics (3:15) – We have to show up (4:30) – What is the NPA? (7:30) – Non-Profit 101 – How is NPA Run? (9:15) – Not Just Federal: Challenges in States (10:10) – Will uninformed legislators ever understand creatine?! (12:30) – Performance Supplements Lead the Way in this Industry (14:00) – Should the dietary supplement community discuss supplements for children (16:00) – The four pillars of the dietary supplement industry's regulatory framework (23:00) – Dan's Background at the FDA (24:00) – Dan vs. USPLabs (28:45) – What can be a dietary supplement? (32:30) – Botanicals and Constituents of Botanicals (35:15) – Foods and supplements cannot intoxicate (38:00) – New Dietary Ingredient Notifications (NDIN) (39:30) – Congress... Read more on the PricePlow Blog
Daniel Fabricant, Ph.D served as the Director of the Division of Dietary Supplement Programs at the U.S. Food and Drug Administration (FDA), where he directed agency policy, public affairs and regulatory action regarding regulation of the dietary supplement industry for more than three years. Today Dr. Fabricant is CEO and President of the Natural Products Association (NPA), the nation's largest and oldest trade organization representing the natural products industry, including dietary supplements, foods, personal care products and more. EPISODE LINKS https://www.npanational.org https://twitter.com/drfabricant FOLLOW DANNY JONES https://www.instagram.com/jonesdanny https://twitter.com/jonesdanny JOIN OUR KULT: https://bit.ly/koncretepatreon OUTLINE 0:00 - Introduction 2:30 - Healthcare in the US 7:55 - How the FDA works 14:33 - Patents / Branded drugs 24:00 - Daniels role at FDA 33:29 - NAC 36:27 - NMN 41:42 - FDA tried to make fish oil a prescription drug 43:24 - Is David Sinclair trying to monopolize NMN? 51:04 - Peptides 1:02:56 - Cannabis & CBD 1:14:32 - Testosterone therapy for men 1:18:50 - FDA pandemic response 1:31:07 - Creatine 1:34:10 - Cancer vaccines 1:40:33 - Universal health care
Last year saw a rise in legislative and regulatory attacks on the supplement industry. Should supplement industry stakeholders be concerned things will continue or even worse…accelerate in 2023? If you caught my recent content regarding the revised FTC health products guidance document, at the very end of it...I stated that whether it was that particular regulatory update, state legislatures attacking supplements, federal legislatures calling for supplement industry regulatory reform, or several questionable FDA moves against the supplement industry…it should be easy to see that the government is paying more attention. I went on to say that this increased attention can only mean major changes are likely ahead. So, buckle up supplement industry…things could get wild here in 2023. It was through some of the comments and direct messages, that I received in regards to the content, which made me realize most of my audience was interested in learning more about what exactly is impacting the supplement industry from a legislative and regulatory standpoint. While I could certainly provide an extensive update myself, this is the type of nuanced trending subject matter that would undoubtedly benefit substantially from bringing on someone that's on the ground fighting these baseless proposals that would damage the supplement industry. That's why, as an added bonus, I asked my good friend Kyle Turk, who also happens to be the Director of Government Affairs for the Natural Products Association (NPA) to join me in an insightful conversation. FOLLOW ME ON MY SOCIAL MEDIA ACCOUNTS LINKEDIN - https://www.linkedin.com/in/joshuaschallmba TWITTER - https://www.twitter.com/joshua_schall INSTAGRAM - https://www.instagram.com/joshua_schall FACEBOOK - https://www.facebook.com/jschallconsulting MEDIUM - https://www.medium.com/@joshuaschall
Who is TINA and why does she seem to hate the energy drinks market? In mid-December 2022, Truth in Advertising (TINA) and the UConn Rudd Center for Food Policy & Health sent letters to more than 40 energy drink companies urging them all to review their marketing. Why? TINA believes these energy drink companies are engaging in deceptive and unfair marketing tactics that are targeting minors. While 40+ energy drink companies were targeted, none more so than GHOST Lifestyle. TINA didn't just send a warning letter to GHOST; they also filed a 22-page complaint against the brand with the FTC and FDA. The complaint detailed how TINA believes that GHOST targets minors through a multifaceted deceptive marketing strategy. It includes GHOST's utilization of licensed candy flavors, partnership with gaming lifestyle brand FaZe Clan, and usage of certain social media influencers. Beyond that, TINA also believes that GHOST failed to adequately disclose that its products are only intended for healthy adults and may be harmful to children and make unsubstantiated and unapproved health claims about its products. In this content I will share my thoughts around the Truth in Advertising complaint, but also why GHOST was specifically targeted, what implications that might or might not have to the brand, and also expanding those insights to explain the potential impacts to the entire energy drinks market. To help add a layer of depth to this content, I also asked Daniel Fabricant, President and CEO of Natural Products Association (NPA), to join me for an insightful conversation on this subject matter. Disclaimer - Do not misinterpret anything in this content for me saying that efforts by TINA have any malicious intent behind them. In fact, I applaud non-profit organizations like TINA for their important role within the business ecosystem. Moreover, if there are data supported changes that would be beneficial, I'm more than happy to work with TINA in some capacity to improve marketing within the energy drinks space. NPA Letter to TINA FOLLOW ME ON MY SOCIAL MEDIA ACCOUNTS LINKEDIN - https://www.linkedin.com/in/joshuaschallmba TWITTER - https://www.twitter.com/joshua_schall INSTAGRAM - https://www.instagram.com/joshua_schall FACEBOOK - https://www.facebook.com/jschallconsulting MEDIUM - https://www.medium.com/@joshuaschall
In this episode of The Natural View, WholeFoods Magazine VP of Media Heather Wainer talks with Kyle Turk, Director of Government Affairs at the Natural Products Association (NPA), about legislation that would place age restrictions on nutritional supplements. NPA is spearheading grassroots campaigns across the country against these bills—in Rhode Island, California, New Jersey, Missouri, New York, and Massachusetts. The campaigns—as well as how you can contribute—can be found in NPA's Action Center: https://www.votervoice.net/NPA/Campai...
https://blog.priceplow.com/podcast/npa-vs-dick-durbin-s4090-067: A bill (S.4090) introduced by Senator Dick Durbin would require PRE-APPROVAL from the FDA for all dietary supplements. Led by Dan Fabricant, Joe Weiss, and Doug Kalman, The Natural Products Association (NPA) is fighting back. On April 26, Senators Dick Durbin (IL) and Mike Braun (IN) proposed a bill titled Dietary Supplement Listing Act of 2022,[1,2] which would have serious ramifications on the way business and commerce is done in the dietary supplement industry. We invited a powerhouse team of industry veterans and experts to discuss what this bill would mean for the industry: Daniel Fabricant, Ph.D - CEO/President of the Natural Products Association (NPA) Joe Weiss - President of branded ingredient developer Nutrition21 and NPA Board Member Doug Kalman, Ph.D - Senior Vice President of Scientific and Regulatory Affairs for The Natural Products Association All Dietary Supplements would now need FDA pre-approval? The discussion centers around the text of the bill, and how its subtle wording would effectively create a situation where supplement manufacturers would require pre-market approval in order to enter the marketplace, otherwise they'd be deemed misbranded and subject to legal action. Quick links before listening Read the bill's text - https://www.congress.gov/bill/117th-congress/senate-bill/4090/text Compose a message to your representatives - https://www.votervoice.net/NPA/Campaigns/94238/Respond Video: PricePlow Invites the NPA to Discuss Dick Durbin's S.4090 https://www.youtube.com/watch?v=Kl5gDfFFGpQ Audio Version Subscribe to the PricePlow Podcast on Your Favorite Service iTunesSpotify Google PodcastsSoundCloud Detailed Show Notes The Natural Products Association is the leading trade association for dietary supplements, known for its strong lobbying presence in Washington D.C. It acts as an industry watchdog on regulatory and legislative issues. 0:00 - Introduction to the situation 0:40 - Guest introductions 3:30 - Dan Fabricant's opening statement: This is a listing bill, and in many ways, the agency already has the information this bill would mandate. Signed in 1994, DSHEA is the prevailing law of the land for the dietary supplement industry.[3] It was designed to give consumers access but with consumer protection, and it's done a great job of balancing those two. It's one of the safest commodities the FDA regulates, if not the safest. This bill would restrict access and restrict the industry's size, while limiting consumer choices. A listing authority "This is designed to give FDA a listing authority, where they're going to tell you basically what you can and cannot set your shelf with. That's a problem on a number of levels." 4:35 - Pre-Market Approval What we're really concerned about is the pre-approval aspect of this bill. "This is effectively pre-market approval for supplements... we don't have pre-market approval for orange juice or chocolate chip cookies or calcium in milk... so this is really odd". 5:00 - NDI (New Dietary Ingredient) Dan explains how new dietary ingredients are brought to market through the NDI process.[4,5] But with this bill, if you are using old dietary ingredients in the market, and merely change the flavor, you need permission from the government to go to market?! You have to make the list to go to market?! Seems very excessive. 6:15 - The bill's vagaries: The crux of the issue: combining two critical parts of the bill Dan reads a couple parts of the bill's text: "...commercial distribution which has not been included in any listing previously submitted by the responsible person to the Secretary under this section shall be submitted to the Secretary prior to introducing the dietary supplement into interstate commerce."[2] Seems benign enough, just give them a listing. But wait,
All right. Welcome to the gut check project. I'm here with your host, Dr. Kenneth Brown. I'm Eric Rieger. This is gut check project, Episode Number 26. We're going to wind up 2019 with some awesome info. What's up, Ken?What's going on Eric? How are you doing, man? Episode 26. Unbelievable. I apologize if I'm a little too sexy today because I'm just coming off of a small cold. I think the hottest people are those that are sick.Well, I'm not sick. I'm post sick. Remember, the viral prodrome. The reason why we always like pass so many viruses is that you tend to pass the virus before you even know that you're sick by the time you're actually sick. You're probably okayYeah. At that point you can go back and say I heard you might be sick. I was too back then.Yeah, exactly. Good to see you?Well, today's episode is going to be pretty awesome. We're going to tackle number one, we've received tons of email in your clinic because you also sell the KBMD CBD at your clinic, you get these questions. These have been coming in Fast and Furious over the last little over 14 days. And it's questions about the safety of CBD oil and its application. So we're going to tackle that I do need to tell everyone. Thank you. We're on episode 26 because the first 25 shows were so well supported by all of you who've been keeping up with a gut check project. We grow every single day. Paul, the guy who's helping us put together the production now and helping us spread the word. We just hung up the phone with him. We've gotten more and more downloads each week. So thank thank you every single one of you for liking, sharing, emailing, telling your friends about it. We sincerely appreciate it.We learned so much about it like today we have a new a different guests we do Instead of gutsy our little mascot or green frog, but since we do film on a green screen, he gets blocked out did not know that didn't even realize that. So now we're going to go with a dung beetle, right here? Yeah, yeah, we did. So that's Dilbert, the dung beetle,Dilbert, the dung beetle. So one of my favorite things is whenever we're bringing any patients back and somebody sees you, and they're like, hey, you're Eric, I watch your show that just warms my heart. So if you happen to be a patient and show up and you watch the show, if you say that it just makes us both feel really, really well...needed wanted, appreciated.Yeah. At least outside of me putting you to sleep. Take five or six good deep breaths. Exactly. Today's episode is sponsored by Atrantil. Your bloating relief, it's what we do. So go to Atrantil.com or lovemytummy.com/KBMD. Today it's also sponsored by KBMD CBD oil. You can find your own KBMD CBD oil at kbmdhealth.com which of course, the initials KB, Kenneth Brown, it's endorsed by the guy who's sitting across the table from me. So Ken, why is...What does MD stand for? Well, I'm not really sure.I thought it was your buddy Mike Doyle, but I don't know.Yeah, it's probably. So tell us a little bit about KBMD CBD. Alright, so KBMD CBD oil. I got involved with the science of CBD because I saw the beneficial effect with my patients when we developed Atrantil I then learned that the science of Atrantil the polyphenols in it actually augment CBD. So I'm seeing this combination do incredible things for people. So this particular CBD is one that we have researched, I've seen it work clinically. And we know that it comes with a certificate of analysis. It is organically grown, it is naturally extracted with co2, so it meets all the criteria that you want in your CBD because this is important. The rest of this podcast is going to be all about the dangers of CBD.Definitely and It's really interesting since we do have so many people who have begun to purchase CBD find benefit. It's really kind of weird what's occurred over the last two weeks. And what I would say is a little bit of misinformation. But it's more or less probably just misunderstood information and or or misapplied information. But regardless, the benefits of CBD used correctly, have been undeniable with the people who've come back through the clinic with people that we've scoped, and how well that they are doing. And so, hopefully today, we're going to provide some context on why more or less the dangers that you may or may not have read about in the news recently are really a little concerned. But we'll, we'll see. We'll see how far along we get in at the last. The last thing. Our last sponsor is the KBMD health box. You can find KBMD health box by going to kbmdbox.com. Now last week we did a full unboxing which is something I think we're going to try to do at least once a month. But essentially, if you want almost $300 of physician vetted supplements that can help you benefit your life and get them for only $147 which you would spend, not you would spend more than $147 worth of time driving somewhere to pick them out for yourself and having someone handpick them for you. Go to KBMDbox.com. What was one of the things that we had a patient come through just earlier this week, who showed us his lab results that he took to his primary care physician? So we're starting to make a difference in the landscape of health here in the DFW Metroplex and different places. I've been getting emails and calls from people around the country that will actually hear the podcast and then they'll want to sign up for the box. And what we're seeing is that these vetted supplements actually are making a difference with both subjective how they feel and objective the labs. So the reason why I chose these things is they all have third party analysis. And they all have some scientific background that actually explains how they're going to help you. So much so that I'm thinking of ordering my household, another box. So although it is the KBMD Health box, I actually I love the fact that I can get these things that I'm going to purchase anyways, they come into my house, so my whole family's on it. Now we're running out of stuff. So I'm gonna end up having to double up on everything. So it's one of those things that I feel really good that we can look at different aspects. And when somebody says, Oh, I tried X, Y, and Z, I didn't notice anything. I'm like, oh, did you try one that had a third party analysis? No. And then they do and they're like, Oh my gosh, big difference. Same thing with CBD. I mean, a lot of CBD out there doesn't really have what's on the label. And we're going to get into that because we're going to talk about what the FDA thinks about it. We're going to talk about the different media and what they're doing, and hopefully get into all that but that's the whole point of that box is I want to deliver these vetted things to your house monthly so that you can continue to improve your health. Hundred percent. So without further adieu, be sure to like and share the gut check project. We certainly appreciate all of the support to date. We're going to hop right into it. So what we've received here recently is a lot of speculation and concern from people who have said, Hey, I'm interested in CBD. I know that you and Dr. Brown have heavily studied, been entrenched with CBD and its application over the last few years. I just learned that the FDA is associated or made public a study that says that it may be hepatic toxic or bad for my liver. It's, unfortunately, it's a weird jump off point. So I'm going to kick it to you. Because immediately I had lots of different thoughts and instead of getting emotional, what did we do? We went and tried to find the sources of where this information came from. We want to backtrack on how they got to that conclusion. And I think that we can put a lot of questions at ease and even help people learn how to be a little bit more critical with the data that they receive when they receive it. Because let's face it, lots of stuff that we see on the internet, or that we hear on the news or reading the paper, it's basically clickbait. It's basically things to keep you engaged, whether or not the actual substance is worth the headlines that are written so...So what you're referring to is recently the FDA put out a statement, a consensus statement in the news and it's making all kinds of traction in the news that they're saying that CBD is not as safe as people think not only that it can be harmful. Now this has bled onto TV and my patients have been asking me about this FDA statement. Then there's been other news articles like the one that Forbes published, read said that CBD causes liver failure. Failure. That was the title liver failure caused by CBD. I want to get into all that I wanted to take a really deep dive into the science of all of this as a gastroenterologist, I'm board certified gastroenterologist, which means not only am I a simple country, butt doctor from Texas, but we actually have to learn liver disease, hepatology, I'm not a hepatologist like some of my other friends where I send like really complex things, but we at least have to understand the liver, how it works and what it does. So a lot of these articles discuss this but they don't clarify so many little things. Because and they shouldn't it's a it's a journalist writing an article they want they want it to be shared. And anytime you mentioned CBD, anytime that that is thrown out there, you're going to get some clicks, you're going to get a whole lot more clicks. If you say you're going to die from taking CBD. It reminds me of the I remember Jerry Seinfeld was on Saturday Night Live one time and they were making fun of the nightly news where they always do the promo at like three o'clock. Like five household items that are guaranteed to kill you, tonight at six.You're like what? If it was so important, they probably wouldn't make you wait.No, I'm gonna die before you put this on the air. So what I'd like to do is talk about the briefly the science of the endocannabinoid system and CBD, then do a little bit deeper dive into the liver. So everyone's going to get a primer on the liver 101 here, because these studies don't make sense unless you know, some of this knowledge. It's just sensationalism. For some of it, some of it is a little bit unfair. I think some of it is for what the FDA got, and it's there. But I just want this podcast today to be something that can be useful for industry people that can be useful for patients or people that are thinking about taking CBD and it can be useful for a subset a small subset of people that may be should not consider taking it. Yeah. So all of this is kind of, you know, for the future of this podcast, It's almost going to be a bit of a rebuttal. Not necessarily a defense of hemp derived CBD. But let's just buckle up and kick some science. This might be a little bit I don't know how long we're going to go where we're going to go with this. We're just going to feel it out and see what happens. But I at least want to be able to explain why I still believe that a lot of people should be taking CBD even though Forbes is like you're gonna die from this.Yeah. It's not arsenic people. No it isn't and I think another cool application here is there are people out there who have been on the fence on whether or not I should try CBD or is this something that's good for a family member for me? And unfortunately, there you hit this intersection, where a news headline is written that CBD causes liver failure. Well, if they've been on the fence, that's a pretty big No, no, right? So now you've taken away maybe an avenue that they were considering to help them out. What I hope that we can do with this particular episode is basically let's temper and let's see things in context. I think context is a word that as you get into sensationalism is something that is kind of the rescue item. If I could put something into context, then at least I'm giving someone a fair chance to understand the information that's before them. I don't feel like sensationalized headlines do things like that. Then again, I also don't feel like someone who shakes, hand picked or cherry pick studies is doing that either. So what I think today that we can do is fairly evaluate and talk about the process of how the liver works, and why some of these studies are or are not applicable to the nature they were presented.Absolutely. So the first one we got to discuss is what what what the heck did the FDA say? Sure. So the FDA came out and they mentioned that they've got several issues with the safety of CBD. The two main ones that they're really concerned about are potential for liver injury, and interactions with other drugs. What they actually said is that they're concerned that people may mistakenly believe that trying CBD can't hurt the agency wants to be clear that they have seen only limited data about CBD safety. And these data point to two real risks that need to be considered as part of the drug review and approval process for the prescription drug containing CBD. Interesting. Now, what I say this is because the FDA is referring to the data that was presented to them by GW Pharmaceuticals, who has a epid... eipdi..x you know?E-p-i-d-i-o-l-e-xYes, which is the first FDA approved prescription CBD isolate,Right,for seizure disorders.It's important to point out that is not full spectrum. Correct. That is not full spectrum. And there's some that's important because here later in the podcast, and think we're going to draw some comparisons and just if you're listening, just remember, epidiolex is a CBD Only isolate it is not a full spectrum product.So let's talk about what the FBA what the FDA actually does. So the FDA has a really daunting task. The Food and Drug Administration is responsible for protecting the public health by ensuring the safety, efficacy and security of products. So it is super daunting because there's a lot of products hitting the market, and the FDA has tried keep up with this to try and protect people. And let's be honest, let's look at the elephant in the room. The elephant in the room is that there are a lot of bad CBD products out there. Yep. In fact, in a jam article 2017 showed that 70% of the CBD products that they looked at did not have what was on the label and what was there could be higher levels of CBD could be lower levels of CBD. So it's a gamesmanship that's going on right now. So it is totally true that you need to make sure that you've done your homework on what type of CBD that you're actually taking. There currently is little to no regulation in the CBD industry. There is the President and CEO of Natural Products Association NPA. His name is Daniel Fabricant. He's a PhD. I love this quote. He's quoted as saying it is well past time to bring science into the equation, as federal rules require safety and Consumer Protection must come first. I agree. And we all agree with that. Sure. And I think that all companies that have reputable CBD companies, they all want that. Problem is when you have these different stories leaking out, which gain much more traction, it just starts creating a little bit of confusion misconception, and then people don't really know where to turn. So the feeling is, is that possibly statements by the FDA saying that it creates this narrative that questions the safety of CBD overall, strictly to address a few number of companies which are producing quite frankly, some crap products.What was the number that we learned the last time that we were in Utah at meeting I believe it was one out of every 23 to 24, I could be off it was definitely in the 20s. But every to every 23 or 24,25, CBD labels available for retail purchase. One is seen as a reputable well marketed or correctly labeled product, which means that even if it happens to be off a little bit, you've got 23 or 24 other labels which are just not truthful or probably not correct, don't have a certificate of analysis or are blatantly, just not even what's in the bottle.100%. There's a lot of people out there trying to take advantage of this wave that's coming. So I do not. I believe that the FDA is doing their job by looking at the data that was actually presented to them Agree. So let's take some time and break all this down for the consumers, health care providers, industry personnel. Starting with the question, does CBD cause liver damage? Unfortunately, or fortunately, because I like science we really need to talk about what the endocannabinoid system is. Because if somebody's listening to this, they're like, Well, I was thinking about taking this but I'm worried becasue it can cause liver failure. I don't know why I'm taking it. Why in the world should I be taking it? So let's do a quick one minute discussion of the endocannabinoid system. Let's do it!All right, the endocannabinoid system. The endocannabinoid system is a system which was discovered in the 90s that we now realize it's probably everywhere in the body. There's primarily two different types of receptors, but essentially, the way that I try to explain it to my patients, it's concentrated more so in the neural areas, nerves, brain and the immune areas. Although we now know it's in every single organ, that's where all the original research was. We now realize that its job, the endocannabinoid system is to produce these products called endocannabinoids. Which work as traffic cops. They just kind of get your body to get back to an area of balance. If you've got too much activity, they go Whoa, slow down a little bit. If it's not enough, they go, come on. Let's go ahead and get some more going here. So you have this fantastic system in your body that really just tries to keep balanced. Think of it that way. And you're going to hear a little bit later why I think most of America is out of balance. I think most of America needs some replenishment of their own endocannabinoid system. So that's the important thing is is that there's a dire need to try and get us all back to a certain balance, because the reality is we're getting sicker as a nation. And one of the causes could be that we took hemp derived foods out of our diet and out of our livestock diet. And there's a theory on that, that possibly that's one of the reasons why we're having more autoimmune diseases, why we're having more of the other problems that we're seeing, Well at least contributing factor.Certainly at least a contributing factor. So keep this in mind. So the the primer on the endocannabinoid system is if you're, if you have ears and you're hearing this, you also have an endocannabinoid system, and you have a higher than likely chance that you are out of balance with that. And if you are out of balance with that, then you probably could benefit from some of this. Sure. So right now you're going well, I'm out of balance, I'm going to probably benefit but I'm going to go into liver failure if I do this. So let's talk about what liver failure means. You have a genius living within you. You probably have multiple geniuses living within you.Thank you. That feels great. Sometimes the voices in your head don't say to do bad things.The evil genius. Yeah.Well, one of the geniuses living within you as this beautiful origin called your liver. So you have this and it's amazing. So to understand where they're going with this, let's talk about what the liver actually does. So we all have livers. And they work differently in every single person, and they can continue to adapt, evolve and change. One of the only organs that you can transplant a partial portion of it and it will grow into a full liver. So the nephrologist think that the kidneys, the smartest organ, the neurologists will think that the brain is the smartest organ The cardiologist says if you don't have blood, you can't think so It must be the heart. Yeah, yeah, exactly. I'm gonna say, well, for health span, smartest organ in the body is the endocannabinoid system. So eventually, we're going to have Endocannabinoidologists. Because what ends up turning out is that the endocannabinoid system is in all these different organs.Correct.They're not completely separated. So let's talk about the liver. The liver is responsible if you ever wonder what the liver does. So do you have any idea what the liver does? I've got a little bit of an idea... Little bit of an idea. So the liver is responsible for selective uptake, concentration, metabolism, and excretion of the majority of drugs and toxins, also known as xenobiotics. So let me just say that again. Basically, the liver takes the crap that you bring into the world. And it says, I'm going to convert it to something useful, or I'm gonna get rid of it for you. Yeah, it can detoxify it, or it can say, Oh, you need to be this and then you're useful. That's why I say it's a genius in your body. And it the liver figures this out, it figures out what you need, and it determines if it's a drug, or if it's a toxin, and it can turn into a better form. Now, one of the problems I have with these different articles that I've been reading, is that they discuss that then enzymatic process called the P 450 system, and they just write it like that they're like, CBD has been shown to affect the P 450 system. What doesn't affect the P450? So that's the issue. So let me break that down, I bring up the P 450 because in the lay literature without even describing what it is, it is a complex. It's called a phase one metabolism of the liver. Under p 450. It's an umbrella term that has over 60 different genes, that code for hundreds of enzymes to break down anything that comes your way. So the P 450 enzyme is like saying, Oh, I don't even know an analogy, but it's top of the funnel down. It's like you just so generic, that you can't just say that. So but they write it in the lay literature almost as a sounds sciency so I'm sure that it's, I'm sure that it's right. That's kind of my feeling on I'm like, why would and all these people it's almost like these news articles parrot each other. And nobody's stopping going, wait a minute, because as it turns out, the P450 system, not the P450 enzyme, the system breaks down almost everything that we put in our bodies. Yeah, no joke. So a lot of going back to the pharmaceutical days, I remember that was one of the biggest challenges with with any of the drugs that we detailed a physician on was, how is it affecting the P 450. And that would be something that they would be all salespeople be coached on that before they would go on calling a physician. But the truth is, it doesn't have to be a compound. It doesn't have to be a medical pharmaceutical compound for that to be somewhat important. Something as simple as grapefruit juice. Also, detectibily inhibits the metabolic ability of the P 450. So there's all there's a handful of different drugs that people who are elderly, maybe caution, don't drink grapefruit juice, because it will inhibit your ability for your body to clear this particular drug. And I say that to say this. It's not nothing is inherently just special because it does or does not directly affect the P450, almost everything you take into your body is either cleared quickly or slowly by that same system.Yeah, so they kind of imply like CBD is the only thing that gets...Not even close....that gets processed in the in the P450 system. In fact, we know that there are multiple medications that can be altered by certain foods. Grapefruit is the most common one, and that really affects like immunosuppressants tremendously and that's where it really came up. When they realized, oh my gosh, you have these different drugs, let's say blood thinners and immunosuppressants, which have a very narrow therapeutic window, you have to have these things like right dialed in. Yeah. And then people talk about grapefruit but you know, other things that have actually been shown to do this cranberry juice, black tea, pepper, even chocolate Yep. has been shown to affect drug absorption and they have been shown to affect certain pharmaceuticals. We don't even know the tip of the iceberg on this because you have to do the study on it. You have to do the pharmaco kinetics, the PK is what it's called to actually determine that which is so funny because they say oh CBD is metabolized by the P450 system. That means nothing. And so if you take CBD and or chocolate and or drink tea, be careful. I mean...I think a good analogy a seriously a good analogy is it the P450 being metabolized by the P450. It may be good for base knowledge, but the truth is, is does it overwhelm that, as you put it system, if it is overwhelming that system, chocolate, for instance, for most intents and purposes would be like a single car driving down a six lane highway by itself. It's not really if the highway was a P450 and the car was the chocolate. It doesn't take anything to funnel that that car through.Correct.The problem is is whenever you happen to overwhelm that system. And that is important to know. But I would say in terms of context, kind of the way that we started this discussion in context. It's not my belief through what I've read and seen that CBD inherently overwhelms or becomes more than a single car down that six lane highway.So not only is it just one single car going down the highway, remember that not only foods but drugs, nobody's talking about drug drug interaction.Right.So there's a reason. So I see a lot of patients that one drug may be very effective one thing may be very effective, but there's so many variables like for instance, drugs, the sex of the person plays a role, you may have different levels, the age of the person and any diseases can all affect this whole system called the P 450 which produces enzymes. So not only that, but then genetics play a huge factor, alcohol intake.Alcohol intake, all of that. I mean, genetically, this may be why some drugs work on certain people and why they don't work and others fact there's a whole field of science right now where people are trying to determine the genetics ato go, Oh, you're going to need a higher level of whatever Plavix which is one that they've actually looked at. Or you can, you're going to take less. So we this is a whole field of this beautiful science where we can go Okay, genetically, you're going to be predisposed to need more medications. So when these enzymes get used up, basically if you've got this one chocolate, which is a car, one on six lane highway, and then you add fluconazole, which is an antifungal, that's an but that's not a car, that's a semi now and then you add alcohol, which is a minivan could be ccould be a couple minivansand then you do whatever something else, but you can see that the liver has to try and process this right. So what happens is it becomes this once it becomes a traffic jam. Then people start getting angry, they start honking their horn that is a rise in your what we call lfts liver function panels liver function test Yeah, so AST and ATL are the two ones that we always talk about, that's exactly what the FDA was referencing. So I want everybody hear this. When you overwhelm the liver with multiple cars using your analogy, then honking starts and the honking the warning sign is this rise in AST and ALT. So, for instance, your body can adapt to it. We've seen this all the time. If you drink alcohol on a regular basis. you build more lanes, you build more lanes, you get really good at metabolizing alcohol. Build tollways. I'll use myself as an example.Not with alcohol.With coffee, Okay.I always have to laugh. Whenever I go to the my own doctor. They say how much coffee do you take? I just write obscene amount because I've down regulated by receptors or I've had the ability to ramp up my my livers ability to convert that coffee into an inert thing and there it is. So you see it as an anesthesiologist or as a crna. I mean, describe what your experiences whenever you try and put somebody to sleep using propofols, different medications.Yeah, well, I mean, definitely, if someone says that they happen to be a large consumer of or a consumer of large amounts of alcohol, it generally takes anywhere between 20 and 30% more of an agent to put them to, to sleep safely, say, But back to your point of body habitus, for whatever reason, even just something as simple as someone being a redhead fair skinned, those people generally take more agent to make them go to sleep. Yeah, let's go ahead and clarify this. This is a well known thing in anesthesia. You're not being prejudiced? No, not at all. No, they literally just for whatever reason, the metabolism rate of someone who's fair skinned with red hair is typically higher than the average calculation and you can go through any types of weight based medications that we use to bring sedation to someone and generally fair skin redhead folks just take more. Is that interesting?Yeah, it is. So that is more than just anecdotal like they've actually done some studies on this and they've actually shown probably because whatever lineage, they come from Scotland, Ireland, they have a higher P450 to metabolize that particular or a higher subset of the P450 systems. So just keep that in mind. So when you take certain foods or drugs, everything's competing for your liver, to do to just say, hey, fix me, you know, figure out what's going on. Fortunately, it is a badass organ and the liver is tough and it can handle a lot, the largest solid organ that we have in the body. So usually it can handle everything. Now the most common example like we've talked about, if you take grapefruit juice with certain immunosuppressants and things then that particular combo because those drugs need exact or how they were manufactured need exact metabolism numbers. Not only that, did you know that like nutrition plays a big role. So, high protein diet will actually affect your P 450 and malnutrition will affect it. of course it will. So those are all of our paleo friends over at paleo FX and such those guys have revved up p 450s. Eating a lot of protein working out a whole lot, they're able to do this. Unfortunately, malnourished people probably can't tolerate as muchNo and they aren't they aren't they honestly they don't have the supply to rebuild the enzymes that are that are used within the P 450 I mean it's just malnutrition is going to deplete all different types of systems, not just the liver.So in the intro, I kind of mentioned that we're getting sicker. And so let's use nutrition as an example. federal policies tightened by the controlled substance act of 1970 essentially banned the production of industrial hemp during the war on drugs effectively we made hemp CBD illegal and put it under the umbrella of cannabis cultivation. Now what were we were talking with Will Clyden of O-hi energetics right, who actually discussed this and he said some cool stuff on this. He back before this when they were they were using hemp and hemp has been used for ever like since we landed in America, hemp has been using hemp has been used in China for thousands of years and all this other stuff that we were feeding because it's a fantastic crop. It's it detoxifies the soil. And it actually works. It grows quick. It's a great crop industrial. What were we thinking making it a banned substance, I don't know, separate discussion. But they've got data to show that when they were feeding chickens, so for everybody out there I had a patient today who said I said Oh, she was suffering from some things and I think CBD would help with and I mentioned Hey, have you ever considered CBD Oh, I would never ever, ever, ever do anything like that. I am not like that. I said, Okay, that's cool. said hey, let me tell you something. Do you know that before 1970 we were actually feeding animals like chickens and cattle. One of the primary things that we would feed them would be hemp, and it's been shown that you can take a chicken egg and it had over 250 milligrams of CBD, right so right now if you're somebody that just spent $200 on your CBD that has 300 milligrams in 1968 you could've just had an egg.A three cent egg.I know 3 cent egg. And I looked at the literature and I and I could not find anything that said death by egg otoxicity. It didn't so everybody that's sitting there thinking oh my gosh, no. I'm not going to do CBD. We were having CBD in our diet. A great Great example, to learn a lot more about this and do a deep dive. Our friend Chris kresser had Will Clyden and the CEO of O-hi, O-hi energetics on and he went into this tremendously. It was so cool. It was just like I just it's crazy that we stopped like, and I as a physician have seen that we are getting sicker as a country. So in 1970, we've got since 1970. We've got more chronic disease, we've got more dementia, we've got more autoimmune disease. coincidence, like we said in the intro, maybe it's at least a contributing factor. And now we have the FDA saying that CBD can be harmful yet it was in our food supply up until 1970.That's nuts, dude.It is nuts. And it doesn't make sense and if you look at mean hemp seed, birds eat seeds, birds consume seeds, they do all kinds of things where they can they take in product, What's the matter? No, I'm just looking at I'm trying to make sure we get through everything.Okay good, but I mean they eat everything and people have been consuming eggs from not just chickens they've been consuming eggs from all different birds on the planet for that long. The fact that we've restricted hemp growth etc has only taken away one of the natural things that birds were eating.If you're if you're really interested in this like I said go to Chris Cressors podcast where he's got Will Clyden on there is really cool wills smart dude Chris is super smart dude. So those guys those guys kick some crazy knowledge.Right?So that is it's weird that we're talking on this episode about CBD causing hepatotoxicity. And we've already shown that the liver's pretty badass, right? It can do a whole lot and we've already shown that the endocannabinoid system is necessary and since 1970, or up until 1970. We are taking in significant amounts of CBD in our dietRight.Weird.It is weird, but it's not so weird when we get down to why everyone's alarmed. So you want to get into a...Now let's go ahead and look at the studies. So that is sort of the phase one of this podcast because now we're going to start geeking out a lot. So I hope I didn't hope I didn't lose everybody with a but you kind of need that background to understand what we're going to talk about next.Sure, you definitely that background.Alright. So what they're talking about is the FDA published this revised consumer update. So this is the consumer update that they put out there for everybody detailing the safety concerns about CBD products. Now, this was based on the studies provided by GW Pharmaceuticals, GW Pharmaceuticals has done multiple different studies looking at different things to get their FDA approval. And I'm going to say right now, that kudos to GW for being the first company to step up and really try and make something for a group of people with intractable seizures have an alternative. Kudos to the FDA for doing their job and looking at the data that was presented to them. What I'm going to do is go next level and say, Well, you didn't look at everything. That's the bottom line here. So I'm not bashing anybody. Let's make let's make certain of this. Sure. So there have been several randomized, controlled and open label trials that studied the effects of epidolex, I'm going to call it epidolex from now on it's just easier, which is a 99% pure oral CBD extract on patients with refractory epilepsy. So this in turn led to the FDA approval for two diseases, dravet syndrome and Lennox-Gestaut syndrome. So if you recognize those names, bless you, because you're dealing with some serious stuff, It's a serious seizure issue. If you don't know those. Count your blessings. It's one of those times to go well, no matter where you're at in life. It's like well, thank goodness that I don't have to Deal with a child that has this because that's, that's a really big deal. These are intractable seizures. So they looked at the data on that. And in these studies, the kicker here is I'm going to say it again, getting back to the lane highway, the patients maintained on their stable drug regimen with a median of three anticonvulsant drugs. That's important. It's super important. Three anticonvulsant drugs. So when we use the analogy of the car on the road, imagine a six lane road. And three of those roads. Three of those lanes are double semis.Yeah, that are closed construction... Or closed, Yeah, that's more likely or closed. So let's talk about that. So when we're talking about three different agents used to control seizures, some of those agents would be and I'm assuming here, but probably Depakote, probably Dilantin, also known as phenytoin, or fosphenytoin, which is seravex. There's a handful of anti seizure medications and through my knowledge, all of them, all of them have been recorded as raising the enzyme levels used by the liver which of course would lead to ALT and AST elevation, showing that the liver is essentially working overtime to long term process these drugs right or wrong?Correct. Correct, which is exactly what the FDA is supposed to do. They're supposed to look at this data and go Okay, so let's just look at the study that they're talking about. So the FDA accumulated this data, and they looked at what GW presented GW presented in isolette of CBD, not a full spectrum. And the dose they ramped up to 20 mg's per kick 20 mg's per kick. What that means is a guy like me would take 1954 milligrams a day.That's a lot more...of CBD isolate. Now I see the effects, beneficial effects of taking KBMD health CBD 15 milligrams twice a day,that's 30 milligrams,that's 30 milligrams.The exact dose of what makes people feel better is very argued because all the data coming out of Israel shows that a lot higher doses, but I'm seeing effects at these doses So let's be real quick let's stop for context. So right now at this intersection what we're what you're saying is with a full spectrum and we said this at the beginning of the podcast that what GW Pharmaceuticals has with epidiolex is a CBD isolate and what they've done...You're saying epidiolex now that's funny. Yeah, whatever it is, Well, because I started with that. Then you told me no, that's not how you say it.I think we should switch it up the whole time. EPA max the way it was edimax. What they did is they were able to establish that almost 2000 milligrams for you would be the ideal dosage however, you...isn't that correct? That's the dosage that they went for or the dosage that they felt was safe, Safe. Okay, I'm sorry. So but but on the upper end of... That was what they were aiming for on everybody. In essence, though, from where you have had beneficial effects, you're talking 60 times that amount, two months worth, is what they are saying the safe level would be in one day where you're finding the beneficial spectrum. So just just in terms of context, full spectrum, CBD, one 60th of the dose that they're saying it's a it's a safe level is really all that you need from our experience.Yeah. Now in GW's defense, let's look at the data. So in dravet syndrome, seizures dropped 39% and in Lennox-Gestaut 42%. So... that's good. So they probably did their homework and said, well, we need to get up that high to actually help that so I don't know anything about that. I'm not a neurologist. That's where it's at. But I'm just saying that when we look at that dose, no average consumer is going to be able to consume that Much CBD in a single day, unless it comes through this 2 full grams a day is more than most take Yes,yeah. Now here's the problem 94% of the people had side effects. Okay 94% at the highest dose compared to 75% placebo, kind of weird. So there's just a huge placebo side effect profile that doesn't get discussed at all.Did they say what it just had a curiosity do they state with the placebo was for the control,They did not stay with the placebo was oh, I take that back. I don't know what they use, but basically they left people on the same medications. So, essentially, let's just look at this and say okay, but the good news is, most of it was not a big deal. Most of it was what the FDA also discussed beyond the liver tests and beyond the drug metabolism. They also said Oh, CBD can cause nausea. It can cause drowsiness. It can cause all these other kind of nuisance things. That's what they're referring to right here. It's interesting though, that have a side effect profile assigned to a placebo that's that exceeds around the 30% range, because that's generally the throwaway number. Yeah. So we've gone twice away from the throwaway number. And they've had they've had reported side effects, which I'm not trying to over draw conclusions here, but it could at least indicate that side effect profiles assigned to CBD in this study probably weren't solely to CBD, Well, you're dealing with one of the highest risk populations you can get your hands on, when I did clinical research and when we would do a moderate to severe Chron's study. The placebo arm would have tons of side effects because the disease is bad. That's what's going on here also. So most was not a big deal, upper respiratory tract infection, somnolence, decreased appetite, diarrhea, blah, blah, blah, blah, blah. But the one that they focused on is the increase in amino transferase concentrations. This once again was a revised consumer update, they put this out to the public and their statement is increase in liver amino transferase concentrations when I just got done explaining what the liver does. Did I ever say amino transferase concentrations? No. I said liver enzymes. right? frickin talk to the public if you're going to release a consumer paper. yeah, liver enzymes. AST ALT. This is hiding behind scientific garbaly goop. It's like you're doing half science half anyway. But but whatever. So a patient show up and they're like, I need you to check my amino transferase concentrations. I'm like, Whoa, why? They Hand me this, this, this news article. Right? This is what we're trying to address right here. So what they found is that in the higher dose, 20 mgs per kg, there was a rise in some patients in three times the level which is significant, so if your normal is 20. You can be 60 if your normal is 40 it can be 120. When patients come into me and it's three times the level it sounds alarming. Do you know what happens when somebody gets hepatitis A acute infection? It's way more than that thousands of times the level when somebody goes into foaming at failure there AST and ALT will go from 40 to 10,000.AST and ALT have risen for almost everyone who's listened here, way more than three times throughout their lifetime multiple times in acute or in very isolated settings. It happens with illness.So getting back to your highway analogy, which I think is really cool analogy. I'm glad you came up with that. Thank you .Getting back to the highway analogy. 80% of them were taking a drug called valproic it matters Depakote Yeah, that matters. That matters a lot.It's when you take these medications, which is why at the beginning of the show, I said you're more likely don't have to worry about it. But if you're on certain medications, keep it in mind. Now that being said at the lower dose didn't see this stuff. So there is a dose dependent usage of the P450 enzyme you can if I give you one drink, or if I give you a bottle of tequila 512 which in my opinion is really one of the tastiest, most fantastic tequilas you can ever get your hands on. It is delicious. It's delicious. I'm gonna I'm gonna digress right here. Oh my God, Tequila 512... Also sponsored by Tequila 512Tt was really good seriously, ummm in every single person with liver test rose.They went back to normal if they decreased the anticonvulsant or decreased the CBD. So either one it went back to normal. So it wasn't number one, it wasn't permanent liver damage. More than likely correct they were able to return back to normal. And number two, it was simply A case of an overwhelmed P450 pathway more more than likely.So you want to get really confusing? Not really but we might as well try. I don't want to but here's what's really interesting, then they kind of get a little geeky. So GW presented their their stuff and then they showed that the P450 in this enzymes and they went into will, the CYP to, 2c19 CYP three a four can inhibit the CYP blah, blah, blah. Those are all just cytochromes people. Those are all just cytochromes It's under the umbrella of P 450. That's how complex this is. Yeah,It is nuts how complex. The highest plasma concentration to CBD occurs within two to three hours after exposure to the Epidolex. With medication, so timing of these medications going to play a role, which actually got me down a weird rabbit hole where i started thinking. We haven't done this much analysis on what happens if you take your Ace inhibiter and you take your cholesterol medicine, timing wise PK analysis on different people and everything. Because when they do these pharmacokinetics, they do it to get the FDA approval, they do it on people that are healthy, that they can understand it. Let's put this into context again, if you're listening to this you've ever taken tagamet. Have you ever thought about when you take your tagamet, you probably only take it whenever you're afraid that you're going to have acid problems, right? Cimetidine?Yeah, guess what? It's also known as a high level p 450 inhibitor if it's over consumed. So I guess what I'm saying here is, there's probably way more alarms being driven over something that yes, is handled by the P 450 system, but is far less invasive or it's much it's a much smaller vehicle on this highway than some of the other things that the alarms are not sounding over.And then surprise surprise after I just got done talking about the liver and the genetic variability and all these other things. When they looked at the pharmacokinetics there was tremendous variation. Hmm. Weird. Yeah. Odd, right? So and anybody that's listening to this that is a, a pharmacist or is a scientist or like Well, yeah, duh. Like I know, duh. But why put out such an alarming statement? Yeah. Without context.Yeah, yeah, you're right. So it for Okay, so it's a little bit of clickbait stuff, right. And so maybe even the journalist who wrote it doesn't understand specifically, the implication, they may have only seen P450, written somewhere turned to a health care provider and said, What is this? Well, that's indicating that things are rising up, they freak out. They write a headline that says CBD causes liver failure. I just learned that from this health care provider. So I'm going to write this piece.Well, that we're going to get into that. The liver failure. This is still just the FDA. Oh, yeah. To the consumer. So I hope that the FDA looks at this and says, You know what? That's right. All that stuff that was just being said it's right. But we didn't have the time to do it. We couldn't sit there put that on paper, we'd lose everybody. I get it. It's quite true. We all we all but we all have a responsibility, much like any doctor to try and explain. You and I have this ability to have this forum to reach hundreds of trillions of people.Yeah. It eflects in our subscriptions on YouTube. They so many trillions of people subscribed, they started his back over to about 200. Yeah, so every time we got trillions, they start back over. Yeah. So So anyways, so what what you're realizing here is exactly what we're talking about. When you put stress on the liver. The liver honks its horn and does a little rise and the lfts goes, Well, hey, guys, maybe not so much. Can we just back off the traffic a little bit and see what's happening here. So additional studies have shown that levels of the anticonvulsant drugs actually caused the daily effects. So now we start wondering that the that the CBD may actually rise some of the anticonvulsants and then you have more side effects from that comes down to the same thing we're talking about how many things do you want to tax your liver, that's the bottom line. To summarize high dose of a pure CBD isolate, not full spectrum, while using a mean of three other anticonvulsants can cause temporary rise in liver tests and affect the metabolism slightly of the anticonvulsant. Of note, it did not happen at lower doses. So one more time, if you are on an anticonvulsant discuss with your doctor and make sure that you stay well below the 2000 milligrams a day. Yep. So this whole thing of Oh We're going to block the P 450 the P450 is So frickin complex, it is nuts. So anything you want to add to that, because I'm going to move on to the thing that I really want to, like kind of make fun of No, not really, I just want to say that I think that the FDA, unfortunately, is a very important and serious organization within our government. And I think that for all of the flack that they take their, unfortunately, with any other entity, there are limitations on what it is that they can do. And I do believe that they try their best to fairly ascertain and address situations as they are presented to them. Regardless of how frustrated that one of this may get is we don't get a result from them. A lot of it is just simply because there's not enough manpower. Oh, absolutely. They get thrown everything think about, think if you're in an organization where you know that 70% of the crap that's out there needs to be pulled off the shelves and you're limited. It's a government organization. These people making these statements are MD's. I'm really limited fortunately, I have well, we have the show where I kind of enjoy looking up some of this stuff. Fortunately, we have some friends of ours that are that work in the nutrition industry that are fantastic at researching articles. And some of that gets gets brought to me I want to make sure that we all get better this is the whole purpose of this.Hundred percent.I want to help the FDA and help GW I want to help the CBD industry. I want to help all of it. But let's just talk about this because something super weird happened. And this is the one that got the most press A Forbes article came out that promoted a mouse study and made the sensational claim that CBD causes liver failure.Yeah, that's kind of what I was referencing earlier. I may steal the thunder but yeah, you're right.Yeah, so this is you're exactly right. In the intro, you said it was clickbait. I really after looking at this study after pulling the study, because how many people read that article are actually going to pull the study.Well is the is the person who wrote this study that well versed in reading studies like that. I mean, that's that's an important thing. I mean, they I think that probably even the author of the article feels like that they are doing a service to the reader, but probably doesn't understand. And if they do, then shame on them, but if they don't, I think that would be a better explanation doesn't fully understand how to read the study and the quality and the qualifications of that study to make a statement like that.Yeah. And you know, this, this could be an arguable point, I'm sure that the person that that wrote this feels very strongly that what they said was right, the bottom line is the goal of this study was to investigate CBD cannabidiol hepatic toxicity, meaning liver issues in an eight week old male mouse. So they they took a group of eight week old male mice, and then they gave them a CBD that they produced. The CBD that they produced and Will Clyden will just jump up and down when he hears this because he decided Is this on Chris Cresser's podcast. The CBD that they produced was used to extract using hexane, which is a molecule that is known to be hepatotoxic. Yeah, you're not supposed to have heaxane. Don't do that! Will Clyden talked about the fact that if you find a CBD with an outrageously high amount of of CB, if you find a full spectrum CBD with an outrageously high amount of CBD more so and the price ranges, okay? Because what they did is they extracted that with hexane in a cheap way and threw it in their bottle and said, there you go. Now you can check that's got 10,000 milligrams of CBD or whatever. And it's really interesting because there's so much going on in the industry like this. So this particular study out of the University of Arkansas, took the CBD, or they made their own CBD using hexane which is a hepatotoxic in itself and in their certificate of analysis. It was there and then they gave it to these mice. Second thing neatI don't even know there has to be a second but we can hear it. Because I mean seriously, that's, that's like saying, I know your stomach hurts. You should take this Pepto bismol. And then I don't tell you that I've broken up some glass shards and have you drink it and you're like i'm bleeding now! What's going on? I'm like, I don't know. Yeah, but you only paid half the price.I made it myself.Which, by the way, that last batch of propophol that you did in your bathtub is working phenomenally. I'm sure it is. Now we do not make propophol in our bathtubs.Alright, so the second issue. If we have any mice that are subscribers to our show, or listening, I would like you to have your children removed from the room at this moment. Because they took these poor mice, and they gavaged to them. Would you mind defining what gavaged is? I think it's when you kind of force feed somebody I don't think it's willing. That's your I think gavaged something you kind of threw one at me there I think to gavaged someone you basically introduce a funnel to the esophagus and well you kind of get after it, don't you? Yes, I'm currently gavaging my mic right now trying to figure it out. I just undid everything. You're gavaging our ears with your, your microphone adjustments?All right, so gavage is they forcibly give these mice?The CBD extract? Yeah, I don't think it's comfortable nor pleasant.No typically through a tube feeding or down the throat to the stomach is how they generally gavage things. A quick side note, now because I'm now all of a sudden I feel like I'm living in a glass house when I was an undergraduate student. I actually did my first surgery on a rat and we took out their adrenal glands. And I'm just saying that so I don't want to sit there and pretend like I'm not done mean things to an animal. But that was when I knew immediately I could not be a bench researcher. I did not like that. At all, now I was like, I need to, I want to heal. I want to heal. I don't want to hurt these animals, but it's it's a whole separate discussion. So anyways, so they gavage these animals with different doses, and it's really interesting. Now in what they call their defense, they call it allometric dosing, which means they're trying to get the body weight to human weight ratio appropriate. I've read some rebuttals of this article where it is a joke, you just can't do that. And when I read vitamin weed Michelle Ross? Michelle Ross, when I read vitamin weed she dis... she specifically discusses why research on CBD versus mice is very difficult to do because the weight basing the endocannabinoid system is different, all these other things. So allometric dosing being said, assuming that they're saying it's right, so the dose would be the equivalent of what they gave and What a human would give So I'm doing the allometric dosing, which I think is actually higher than what it actually is separate thing. They took mice and they gavaged them with zero milligrams of hexane derived CBD 246 milligrams per kilogram 738 milligrams per kilogram or 2460 milligrams per kilogram of dirty CBD. It doesn't make sense dirty CBD isolate. So for instance, in a horrible alternate universe where humans are now the test subjects and we have large mice which are running tests on us, and they decided to gavage me with the same thing. That would be the equivalent at the highest dose of 241,080 milligrams of hexane derived CBD isolate. I'm not even sure what the hexane would do it 240,000 milligrams 242,000 milligrams.No I mean that being the more or less than now at this point, it's just an additive. It's just I mean it's it's not an excipient It's a straight up additive. That would not make sense at all. Oh, it's crazy.It's poison.This article came out in Forbes and said CBD causes hepatotoxicity. Also hexane causes hepatotoxicity.It is nuts. Alright, spoiler alert. The mice suffered hepatic toxicity and death at the highest dose. Shocking... You know what? I also hear it's bad to have breakfast cereal with not milk but drain-o. Just something that I'm gonna go out on a whim. Don't think you're supposed to do that. It just doesn't make sense. It's It's It's not. That is not an apples to apples comparison if you're talking Okay, so we talked about it earlier. reputable CBD source there is no reputable CBD producer that's going to have and Will special shout out to you it's going to have hexane as a byproduct or an excipient in their full spectrum COA approved which is also why KBMD Health with powered by olyxenol hundred percent is does not have that. I mean they do co2 extraction, which is the important thing which is a reason why we partnered with them to make that product. So we are the one out of the 23 or 24 that is the safe and trusted COA back no hexane etc etc. Doing this study is not an apples to apples comparison on what would happen because who knows? Who Okay, I don't get it because GW we already did that study. They determined that 20 Meg's per kg which is still a shit ton. It's a lot. It's a lot. Yeahis the safe maximum dose. These guys went times it by 100.Yeah, they did.And see what happens? Yeah, it's it's a bad it's a bad comparison. I mean, yeah, honestly, if you wanted to find out if CBD plus hexane causes liver toxicity at a ridiculous amount, top to bottom, then that's a great study outside of that, since nobody does it, I would say it's a bad study. Speaking of road, that's a road to nowhere.Yeah. And so study like this, uh, like you had mentioned is essentially it's not science. It's clickbait. Yeah. And right now that that author, that journalist is just kind of laughing. He's like, I know, and now you're bringing it up, and I'm going to get another whatever, because that's what people are trying to do. They're trying to get attention at this point.So at that point, good for you, you got to click but I would be truly interested if possibly that particular journalists would say, you know what, I didn't fully understand it. I mean, that's okay. Let's look reading studies, right? There's there's a study to reading studies. I mean, we heard that we heard the breakdown that kresser did on Joe Rogan is he Twice had to address his approach to completely different topic about the the plant based diet and then how he had to re approach that with the rebuttal. All that just simply to say, there is a science to reading studies and being really good at understanding what is and is not applicable and then how to find studies that you can compare to each other for good meta analyses. So what we're doing right now is I'm telling you that maybe sometimes there aren't studies, but my anecdotal evidence, I have a busy practice, you hear the patients, we hear them talk I listen to them, when they say that doesn't work. I go, Okay, I'm not publishing it. I don't have time to do that. I wish I did. If I published everything that we're gathering data on, if we're looking at, you know, just so many different things, CBD is just one of them. We've got I love I'm a huge fan of brain.FM for the ability to use sound to change your mood. I Would love to they're unpublished, a lot of studies on stuff like that. There's, there's tons of stuff. So when people go, oh, the studies aren't out there, there is something to be said about the Socratic method, or I'm sorry, the paternalistic method, the way that medicine used to be where the guy in front of you that saw thousands of patients, this is the method that he has. You see me scope, I mean, there's a difference in scope techniques.So they, although some may even still say it qualifies as anecdotal, I will say that there's objective data in both in a scope, somebody can't just come, anybody can come to you say I feel better. Anybody can even if they don't mean it. But they can't make the disease disappear from the imaging that we see in their colonoscopy, or the the mucosal samples that you take. And that's something that's completely objective data. That we see. So those are the everyday results that we see from these types of applications where you just, look it's not made up whenever we okay full pleasure when we first started looking at CBD, I thought was bullshit. Who you looking at?Just anybody who's out there. But when we first started talking about it, I didn't believe it. I was like, man, let's see, because we've been down this road before but we tried new, new without throwing a bunch of things under the bus. We tried new or innovative different things and high hopes. And unfortunately, low expectations and the expectations get met and the hopes are never never realized. The opposite for me personally occurred with CBD over the last three and a half years. And that is it actually stinking works.Dude, I knew that we were onto something with Atrantil, because after we did the initial studies, everybody came back and said, I want more. I knew that I was onto something or I was not on something. I knew that CBD had a viable place in my practice, because I bought and the story goes all the way back which is why we work with which is why it's powered by elyxenol right now, when we went to paleo FX, and I ordered a couple cases and I just gave them away to patients. That was not cheap. Not because I was sitting there trying to be altruistic, not because I was doing charity. I'm like, I don't know. I didn't. And I told everybody, I don't have a clue. I haven't even looked at this yet. All I know is try this. Tell me what happens. And when about 80% of them came back said I want more. And I went, Okay, we're onto something. And that's when I took my clothes off the deep dive into the science and went, holy cow. Yeah,this is crazyUp until that point, I just didn't know there was a whole lot to it. I mean, it really didn't. And then the fact is, oh, and to clarify, it's not like Brown just handed out CBD to just anybody who came to the clinic. You literally just like we did with Atrantil you found very diseased patients to say and who had gone through a gamut of different pharmaceuticals and weren't finding relief, and suddenly they're like, this is working for me. Tell me more about it. And I was, I was blown away.So let's talk a little bit. So we're I'm over here going well studies I haven't published and everything. Let's talk about a few studies. So I've got a Mendeley account, I know how to look at PubMed. I know how to get a Google Scholar, I just want to talk about a couple studies have come out recently. And let's kind of compare it and see if it still makes people concerned that they're going to die of liver failure.Sure. Alright. So in the Journal of Clinical Pharmacology published in 2019, the this was actually a study, also sponsored by GW Pharmaceuticals, as part of the process of getting the FDA approval that the FDA did not reference the best I can tell they did not reference this. This is way more complex and it gets super cool, because what they're looking at is the pharmacokinetics or how CBD is actually metabolized by that beautiful genius called a liver. In high doses in people with liver disease. Yeah, they went through the trouble to take high doses of CBD and give it to people People that did not have liver disease had mild liver disease moderate and severe. This was ballsy to say the least, because using a product like this in somebody with liver disease is is risky. This thing could backfire and it could shut down the whole process. Here's what's nuts, the pharmacologic and safety of a single oral dose of 200 milligrams of epidolex, which is the CBD isolate. They were assessed in subjects they had eight people with moderate or with mild disease, six people with moderate and eight people with severe and then they had this collection of normal people. Blood samples were collected to check for the pharmacokinetics This is how drugs are looked at. They give you a drug and then they check your levels. Basically, the blood concentration was higher in the hepatic impairment and they describe it in nanograms. So the nanogram comparison is that it's a little bit higher in those with severe hepatic impairment. But this is what's nuts there was no increase in adverse reactions. There was no change in blood levels. So basically, the only adverse reaction that they found was a little bit of diarrhea. And it all happened in the mild hepatic impairment. So the FDA had mentioned Oh, studies have shown that it causes diarrhea. What was really funny about
Major trade organizations in the supplement and functional food industry disagree on major issues, such as a legal path for CBD’s use in foods and beverages and whether a mandatory supplement registry would be beneficial. This diversity of opinion is a good thing, says Daniel Fabricant, Ph.D., CEO and president, Natural Products Association (NPA). Different voices and ideas reflect the growth and diversity of our industry, Fabricant says in this podcast with Sandy Almendarez, content director, Informa Markets. Fabricant also details NPA’s stance on controversial issues.
Myriad trade organizations represent companies in the supplement and functional food industries, but through partnerships and collaboration, five prominent groups are working together to offer a common voice in discussions on Capitol Hill and with FDA, according to Steve Mister, president and CEO of one of those organizations, the Council for Responsible Nutrition (CRN). Mister noted the trade groups—the American Herbal Products Association (AHPA), the Consumer Healthcare Products Association (CHPA), CRN, the Natural Products Association (NPA) and the United Natural Products Alliance (UNPA)—are not speaking with one voice, as each trade group has different priorities, but they are making efforts to ensure their messages are consistent. Along with industry collaboration, Mister discusses other aspects of the state of the supplement and functional foods industry with Sandy Almendarez, editor in chief, INSIDER. In this podcast, they also cover: • The strategic endeavor to get multivitamins included in the U.S. government’s Supplemental Nutrition Assistance Program (SNAP) • How supplement and functional food industries can connect and sell to consumers who access their information online • The progress on the Supplement Online Wellness Library (OWL), an industry-led registry that launched just over a year ago.
Daniel Fabricant, CEO and Executive Director of the Natural Products Association returns to the Late Night Health show to talk with Mark Alyn about regulation of the supplement industry and more.Since 1936 the Natural Products Association (NPA) has been working with government agencies to protect the American people. Freedom of healthcare choice is the backbone of this trade association. The NPA helps to maintain good manufacturing practices for both industry and consumers.The question of are GMOs good or bad is not the issue. The NPA has called for a national labeling law for Genetically Modified foods. It's that simple. Vermont has passed a law requiring foods be labeled in such a manner. This is a step in the right direction, but having 50 different laws will put undo stress on national manufacturers that would have to comply with all the different laws. A national rule would allow one way of requiring the labeling. Major GMO creators are fighting this by spending millions of dollars lobbying state and federal officials.Dietary supplements are also in the news. Attorney Generals in several states, as well as some members of Congress are calling for more regulation of the industry. These AGs and Congressional members are uninformed of the current rules established by the passing of the DSEA Act in 1994. The current rules are more than adequate and need to be followed. More regulation would be redundant and cost the government more in trying to enforce new rules.The show also touches on the Health Savings ACT of 2016 which would allow Americans with Flexible Spending Accounts (FSAs) up to $1,000 reimbursement for dietary and nutritional supplements for preventive care options.
Daniel Fabricant, CEO and Executive Director of the Natural Products Association returns to the Late Night Health show to talk with Mark Alyn about regulation of the supplement industry and more.Since 1936 the Natural Products Association (NPA) has been working with government agencies to protect the American people. Freedom of healthcare choice is the backbone of this trade association. The NPA helps to maintain good manufacturing practices for both industry and consumers.The question of are GMOs good or bad is not the issue. The NPA has called for a national labeling law for Genetically Modified foods. It's that simple. Vermont has passed a law requiring foods be labeled in such a manner. This is a step in the right direction, but having 50 different laws will put undo stress on national manufacturers that would have to comply with all the different laws. A national rule would allow one way of requiring the labeling. Major GMO creators are fighting this by spending millions of dollars lobbying state and federal officials.Dietary supplements are also in the news. Attorney Generals in several states, as well as some members of Congress are calling for more regulation of the industry. These AGs and Congressional members are uninformed of the current rules established by the passing of the DSEA Act in 1994. The current rules are more than adequate and need to be followed. More regulation would be redundant and cost the government more in trying to enforce new rules.The show also touches on the Health Savings ACT of 2016 which would allow Americans with Flexible Spending Accounts (FSAs) up to $1,000 reimbursement for dietary and nutritional supplements for preventive care options.
Daniel Fabricant, CEO and Executive Director of the Natural Products Association returns to the Late Night Health show to talk with Mark Alyn about regulation of the supplement industry and more. Since 1936 the Natural Products Association (NPA) has been working with government agencies to protect the American people. Freedom of healthcare choice is the backbone of this trade association. The NPA helps to maintain good manufacturing practices for both industry and consumers. The question of are GMOs good or bad is not the issue. The NPA has called for a national labeling law for Genetically Modified foods. It's that simple. Vermont has passed a law requiring foods be labeled in such a manner. This is a step in the right direction, but having 50 different laws will put undo stress on national manufacturers that would have to comply with all the different laws. A national rule would allow one way of requiring the labeling. Major GMO creators are fighting this by spending millions of dollars lobbying state and federal officials. Dietary supplements are also in the news. Attorney Generals in several states, as well as some members of Congress are calling for more regulation of the industry. These AGs and Congressional members are uninformed of the current rules established by the passing of the DSEA Act in 1994. The current rules are more than adequate and need to be followed. More regulation would be redundant and cost the government more in trying to enforce new rules. The show also touches on the Health Savings ACT of 2016 which would allow Americans with Flexible Spending Accounts (FSAs) up to $1,000 reimbursement for dietary and nutritional supplements for preventive care options.
Daniel Fabricant, CEO and Executive Director of the Natural Products Association returns to the Late Night Health show to talk with Mark Alyn about regulation of the supplement industry and more. Since 1936 the Natural Products Association (NPA) has been working with government agencies to protect the American people. Freedom of healthcare choice is the backbone of this trade association. The NPA helps to maintain good manufacturing practices for both industry and consumers. The question of are GMOs good or bad is not the issue. The NPA has called for a national labeling law for Genetically Modified foods. It's that simple. Vermont has passed a law requiring foods be labeled in such a manner. This is a step in the right direction, but having 50 different laws will put undo stress on national manufacturers that would have to comply with all the different laws. A national rule would allow one way of requiring the labeling. Major GMO creators are fighting this by spending millions of dollars lobbying state and federal officials. Dietary supplements are also in the news. Attorney Generals in several states, as well as some members of Congress are calling for more regulation of the industry. These AGs and Congressional members are uninformed of the current rules established by the passing of the DSEA Act in 1994. The current rules are more than adequate and need to be followed. More regulation would be redundant and cost the government more in trying to enforce new rules. The show also touches on the Health Savings ACT of 2016 which would allow Americans with Flexible Spending Accounts (FSAs) up to $1,000 reimbursement for dietary and nutritional supplements for preventive care options.
Americans love their dietary supplements – vitamins, diet aids, calcium pills, protein powders. The Centers for Disease Control and Prevention estimates that half of all adults in the U.S. use one or more dietary supplement, and the Natural Products Association (NPA), a nonprofit representing the manufacturers and retailers of natural products, estimates that 75 percent of American adults buy supplements at least once a year. Unfortunately, today's supplement market is being dominated by BIG Profit PLAYERS - just like the BIG PHARMA world. It's a slippery slope for a consumer to navigate, with many unregulated products flooding the market. Tonight, Carolyn Dean MD ND, author of The Magnesium Miracle and Death by Modern Medicine talks about the dangers of flooding the body with unnecessary 'health' products as well as how to determine what may be truly beneficial for your body. PLUS in Hour 2 learn about the proper hydration of the blood, body and tissues with trace mineral sea salt, addressing the calcification of the pituitary and pineal glans using ReLyte and great news about what to expect while you're using ReMag and the other Completement Formulas.
Americans love their dietary supplements – vitamins, diet aids, calcium pills, protein powders. The Centers for Disease Control and Prevention estimates that half of all adults in the U.S. use one or more dietary supplement, and the Natural Products Association (NPA), a nonprofit representing the manufacturers and retailers of natural products, estimates that 75 percent of American adults buy supplements at least once a year. Unfortunately, today's supplement market is being dominated by BIG Profit PLAYERS - just like the BIG PHARMA world. It's a slippery slope for a consumer to navigate, with many unregulated products flooding the market. Tonight, Carolyn Dean MD ND, author of The Magnesium Miracle and Death by Modern Medicine talks about the dangers of flooding the body with unnecessary 'health' products as well as how to determine what may be truly beneficial for your body. PLUS in Hour 2 learn about the proper hydration of the blood, body and tissues with trace mineral sea salt, addressing the calcification of the pituitary and pineal glans using ReLyte and great news about what to expect while you're using ReMag and the other Completement Formulas.
Americans love their dietary supplements – vitamins, diet aids, calcium pills, protein powders. The Centers for Disease Control and Prevention estimates that half of all adults in the U.S. use one or more dietary supplement, and the Natural Products Association (NPA), a nonprofit representing the manufacturers and retailers of natural products, estimates that 75 percent of American adults buy supplements at least once a year. Unfortunately, today's supplement market is being dominated by BIG Profit PLAYERS - just like the BIG PHARMA world. It's a slippery slope for a consumer to navigate, with many unregulated products flooding the market. Tonight, Carolyn Dean MD ND, author of The Magnesium Miracle and Death by Modern Medicine talks about the dangers of flooding the body with unnecessary 'health' products as well as how to determine what may be truly beneficial for your body. PLUS in Hour 2 learn about the proper hydration of the blood, body and tissues with trace mineral sea salt, addressing the calcification of the pituitary and pineal glans using ReLyte and great news about what to expect while you're using ReMag and the other Completement Formulas.
Americans love their dietary supplements – vitamins, diet aids, calcium pills, protein powders. The Centers for Disease Control and Prevention estimates that half of all adults in the U.S. use one or more dietary supplement, and the Natural Products Association (NPA), a nonprofit representing the manufacturers and retailers of natural products, estimates that 75 percent of American adults buy supplements at least once a year. Unfortunately, today's supplement market is being dominated by BIG Profit PLAYERS - just like the BIG PHARMA world. It's a slippery slope for a consumer to navigate, with many unregulated products flooding the market. Tonight, Carolyn Dean MD ND, author of The Magnesium Miracle and Death by Modern Medicine talks about the dangers of flooding the body with unnecessary 'health' products as well as how to determine what may be truly beneficial for your body. PLUS in Hour 2 learn about the proper hydration of the blood, body and tissues with trace mineral sea salt, addressing the calcification of the pituitary and pineal glans using ReLyte and great news about what to expect while you're using ReMag and the other Completement Formulas.
Initiatives introduced by the Natural Products Association (NPA) to engage a fresh batch of Congress members are already reaping rewards, says the NPA’s executive director.
Initiatives introduced by the Natural Products Association (NPA) to engage a fresh batch of Congress members are already reaping rewards, says the NPA’s executive director.
Lorraine Heller met with Randy Dennin, chairman of the Chinese branch of US trade group Natural Products Association (NPA), at Supply Side East and asked him about regulatory and other challenges on the Sino peninsula.
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