Podcasts about atrantil

The Healthy Rebellion Radio

Play Episode Listen Later Mar 18, 2021 63:04

Hello Gut Check Project fans. Welcome to Gut Check Project and KBMD health family. I'm Eric Rieger here with my awesome co host, Dr. Kenneth Brown. We have another special show. We just keep we just keep outdoing ourselves with smart people. I'm like I normally I've well I'm becoming very comfortable being the stupidest person on these zoom calls right now this is like this is the new norm, me being the absolute dumbest person on the screen right now.If you're the well, that's thank you. That's really weird. And and if you're the dumbest, then this is gonna be a really, really intelligent show. So today, Episode Number 52. We have a special guest. This is Dr. Charlene Van Buiten. She is an Assistant Professor of food science and Human Nutrition at Colorado State University. Hello, Charlene. How are you doing today?I'm doing well. How are you guys Doing great. We're doing great. I'm not going to introduce the paperwork that we're going to get into. But what I am interested...before we get into some incredible information about your research around celiac disease, and how essentially people can stave off long term inflammation. We always like to get to know a little bit about you. But we did print off your resume. And it looks to me like from all of the stuff that you do in the CV, that you started sometime in the womb getting things done.So you've been like publishing papers in utero somehow.Yeah, yeah. It's it's a really rare skill. So.So where are you? Where do you Where are you from originally?Originally I'm from Connecticut, grew up there. And then did my bachelor's degree at University of Connecticut in nutrition.Nice. And how long have you been at Colorado State?I've been at Colorado State about a year and a half now. So I got about six good months before everything shut down. Still happy to be here. It's a nice place to be locked down in at least.Yeah, yeah. Yeah. Yeah. Absolutely. The northern part of Colorado. It's it's definitely beautiful up there. So before you read Colorado State, let's see where else you were a postdoctoral fellow, obviously. And then, is there any other stops along the way that really leapt out to you and ended up pushing you into Colorado State to do you know, good nutrition for human?Um, yeah, I would say probably the most important step in my whole academic journey was at Penn State where I did my PhD in food science. That's kind of where all of the research that we'll talk about today was really conceived. It was just kind of a one off idea that my PhD advisor and I had just one day, you know, oh, what if we looked at interactions between gluten and tannins, and then, you know, I kind of went back to my office, first year PhD student really excited. And all of a sudden, it was like all of these ideas just in terms of the chemical interactions and what this means for nutrition just designed this whole project. And in a really rare case of circumstances, everything I had designed in my first year of my PhD ended up being what I eventually did over the course of the next five years. I don't think anybody is ever that lucky. Yeah, and the project turned into what you all were able to read before inviting me here. We will definitely dive deep into that. But I'm really curious. So I've, we have the CV here that shows your academic pursuit. I want to know why Charlene, Dr. Charlene, Dr. Charlene decided to do the study of food science and nutrition. Let's just start from there. And then I get the passion once you've latched on to something, but I'm always curious how people find their way like, like, how you how you got there.Yeah, I think I discovered Food Science a little earlier than the average person. Most people will get into it in college, having followed a path of chemistry or biochemistry, and then realizing they can apply all of these concepts to food. But I actually was in the Future Farmers of America when I was in high school. And I thought that I wanted to be a vet, and then realize that I was not really into like blood or sick animals or anything. And one of my teachers was like, we have this competition. It's called food science. you design a food product, you talk about safety and everything. And I was sure sounds cool. And the first day that I met with that team for this competition, we got a textbook chapter on canning. And I was reading about canning, and I was like, I was really interesting. Like, if you can something it'll last a really long time. Or if it's done incorrectly, it can be so dangerous that it can kill you. Kind of dichotomy there. I was like, food science is crazy. And just from there was like obsessed with it. And, yeah, I was for nutrition, grad school for food science.This kind of reminds me of the whole mycology thing that we were talking about before. Where like you might find a brave food canner and you might find an old food canner but you won't find them in the same person. I'm going to just dabble in some aggressive food canning and see what happens. They don't walk around anymore. We were we have Paul Paul Stamets was talking about that. And then the other mycologists, we've talked to mycologists that actually discuss that they feel the same way where it's like, look, you can have a mushroom that will save you. But if you prepare it wrong, or eat the wrong one, you're gonna die. If you have food canning, you can have food forever. But if you do it wrong, you can die. Well, that is awesome. So reading your article, or reading your paper, which is a review of your thesis, which tells me that you know this essentially better than anybody in the entire world because you did a thesis on something that I have been searching for for a very, very, very long time. I developed Atrantil to help people with bloating and irritable bowel syndrome. And then we started learning I late started learning about these effects of polyphenols came across your article, your review, which is titled gliadin sequestration as a novel therapy for celiac disease, a prospective application for polyphenols. This is the thing that really I've been looking for for a long time, we've known the benefits of polyphenols, but you're the first person that has been able to explain why I'm gluten sensitive. And once I start, once I started taking Atrantil whenever I would eat gluten, I didn't have issues, and I really couldn't explain it. We've had patients that say, when I, you know, when I take these large polyphenolic compounds that are in Atrantil, I can eat wheat. Why is it I didn't know I couldn't actually say from a molecular reason. And then I came across your paper. And this is absolutely fantastic. It's 32 pages of incredible material. And 185 references my goodness, you put some work into this congratulations on putting together what I think is the most comprehension review of polyphenols in the setting of celiac disease. So once again, if anybody listened to this, know somebody that has celiac disease, or has a family member, or has celiac themselves, this is something that really we need to share as a community. We need to get this out there and your work is really pivotal to explain the science, which is so cool. So let's jump into it. Because it's awesome.Yeah, I don't even know where to start. Because you you described multiple different mechanisms of action on why polyphenols begin to work. So what drove you to to put these two associations together? Why celiac disease and why polyphenols?So at the time that we came up with this project, I had recently joined my graduate advisor Ryan Elias at Penn State, I joined his lab, and he was doing a lot of work on wine quality. So as a food chemist, you know, we're looking at oxidation of polyphenols, how that can affect wine astringency, etc. And so I was, you know, showed up to grad school thinking I was going to work on wine. And then we found these papers that were studying protein polyphenol interactions using tannic acid with peanut allergens. And so that was an interesting paper doing a little bit more reading, thinking about that. And then thinking about, you know, still wine. And I came across these papers that were using gluten as a fining agent and red wine. So fining is the interaction between polyphenols and wine and a protein that will actually precipitate those polyphenols and take them out of wine to kind of soften the mouthfeel. And so I saw that and knowing that gluten is this immunostimulatory protein, I was like, why are they doing this? That seems crazy to me, and Is it hurting people and you know, it's not labeled, because it's something that's not technically in the product, because it's falling out as a solid. And that was just sort of the the end of the string on that ball of yarn that we kind of started to unravel. Um, and looking at that in terms of a food processing aid, I thought, what if we looked at this from the perspective of a nutraceutical? So if we know these interactions are happening already. Can we flip this around and put it in the human body? Can these interactions still occur? What is happening to the protein? How does that affect the actual mechanism of the disease? And, you know, we just came up with all of these questions from there, but it really started with gluten as a fining agent in wine.That's incredible. That is a that is a lot to peel back as you're starting your sort of academic career to take this on, and then suddenly go down a rabbit hole and you end up over here with a disease. That is, and thank you. I mean, that is crazy to take on that. You just discussed layers and layers that I imagine you were looking at an article that then led to another one led to another one and then you finally went, oh, this is way bigger than I thought.Yeah, there's 185 references on the paper. It's just like the tip of the iceberg.Well just to reset for everyone to those who suffer from celiac disease, obviously know about gluten and want to avoid gluten, but maybe not everyone understands why gliadin specifically, is what it is, is what we're concerned with with its blog. So why don't you explain a little bit about gliadin itselfto ours. So gluten is a heterogeneous protein made up of two subunits. So we have the gliadin, as well as glutenin. And those two proteins will come together forming inter and intra molecular bonds in order to form this gluten protein kind of as a whole. But it's the gliadin that has these repeat motifs in its amino acid primary sequence. And it's usually a prolene. That's one amino acid away from a glutamine, that's going to get recognized in the human body by an enzyme called tissue transglutaminase, or transglutaminase. Two, and that gets a deamidated. And then that's the area of the protein that's recognized by antigen presenting cells. So it really comes down to the amino acid sequence in the gliadin, versus what's typically seen in glutenin. So step back, what you just described is exactly what happens to 1% of the population because celiac disease is the most prevalent autoimmune situation, or autoimmune disease that's there. And what you just described was the amino acids, the prolene, and the glutamine actually form the gliadin. My hearing that right, so those two forms of gliadin.Right, so they're found within the structure of gliadin. So gliadins really are a class of proteins. There's alpha, beta, omega. And then within that alpha one, alpha two, alpha three, there are so many types of gliadins. But sort of this consistent pattern that we see in those gliadins is a really high percentage of prolene, as well as glutamine.Okay.So, in your article, you did describe something that I was I wanted to clarify on this, you described the prolamin glutamine residues and the sulfurus component a pro amine assisting in the ability to find these disulfide bonds, all of that, is that why gluten makes things spongy, because of these disulfide bonds is used in so many things.Yeah. Yeah. So disulfide bonds are formed within the structure of gluten over the course of hydration, oxidation and mechanical kneading. So that's what you see when you're making like bread or pasta, and that dough sort of starts to really come together. That's a result of the formation of disulfide bonds.Nice.Which is what makes it yeah, which it's that texture that everybody that we're that's which is why when you get gluten free bread, you're like, no. Not the same.Yeah, it kind of forms that balloon structure to leavening.Yeah. So I'm gonna I have actually sent back some some gluten free pasta. Can I have some more disulfide bonds in here?Yeah, they don't have that in a shaker Ken. It's not there.That is that is impressive. So what why why gliadin. Why gliadin because we know that gluten is formed of of these two different proteins. But why gliadin being the more problematic protein in the in the gluten molecule.So gliadin is more problematic, because as I mentioned, that higher frequency of the amino acid residues, the prolene, and the glutamine just found in that particular order prolene, something else, glutamine is what's going to make it more recognized by the body. It's also this high amount of prolene results in almost like an unraveled protein structure. And that is something that's recognized structurally by the body as being a problem, it's more difficult for enzymes to break down gliadin because of all of those prolenes, because of that unraveled structure, and then that unraveled structure allows it to be it allows it to interact with that tissue, transglutaminase enzyme as well.So let me stop you right there. So you said something, and that's kind of what I wanted you to say is that gliadins are resistant to digestive enzymes. So you have this thing that your body can't readily break down. So as a scientist, my patients ask, what's the deal? Why is celiac on the rise? Why is it exponentially in the rise? Why are more people saying that they have gluten intolerance, whether or not comedians will make fun of that like, like, it's like, it's something that's in your head, but I am very gluten intolerant, but I don't have celiac disease. So why do you think we're seeing more of it?There are quite a few ideas as to why we're seeing more celiac disease and I know that one of the prevailing hypotheses is kind of based on exposure on whether people have been exposed to gluten at certain times in their life, it's also associated with an overall increase in autoimmune disorders worldwide. So I think that there's probably a link there for sure.So you talked about this, and I'm jumping ahead, but you did show how gliadin can actually create some paracellular leakage, so, so to speak, or that so I see a lot of my patients that will have celiac disease and then show up with another autoimmune disease. So the question is, do we really is one of the reasons why we're seeing so much autoimmune disease like Crohn's and ulcerative colitis could it be precipitated by an inflammatory process in the gut, beginning in the gut? And I just bring this up, because maybe you're at the tip of the iceberg on possibly one of the causes of why we are developing so many autoimmune diseases. What's your theory on as on how we raise these crops, and how gluten has sort of or the wheat has changed over the years from the amber waves of grain to short, stocky plants?Well, in terms of the molecular profile of the gluten itself, I'm not as familiar with that research as probably some other more agronomy focused individuals are, but in terms of actual food products, so what we end up seeing in bread and pasta, the overall gluten content really hasn't changed over time.Really? Okay. That's actually something that I think I was, I've told my patients wrong. I've told them that we're probably getting more gluten, which is one of the reasons why we can have thatNo but I found it interesting, though, because you did reference the alpha beta and omega different gliadin subunits. And then even from there, there's sub sub units of one, two, three, and four, possibly, and as you said, I don't want to press you on this. But maybe maybe the the expression is just simply different from all of those different units over time, depending upon the mean, GMO, or not GMO or hybrid, or, who knows, it's hard to it's hard to say.Yeah, it's also difficult when considering whether there are differences based on those individual gliadins. Because that prolene x glutamine pattern shows up in all of them. repeatedly. Yeah. And in my, in some of my papers, I've focused on alpha two gliadin as one of these specific proteins. And that one just happens to have many, many overlapping at the topes in terms of recognition and celiac disease, but it's certainly not exclusive to just that one subunit.Can you comment on these different subunits? And in your paper, you discussed the the starting point of causing an inflammatory cascade with interleukin 15? I believe it was 15 Have you? Can you comment on that, and that's in the relationship for my gastroenterology colleagues, to lymphocytes because we always look for intraepithelial lymphocytes. And I think you show the mechanism through IL 15.Right, so in the celiac disease inflammatory cascade, we start with the recognition of gliadin by the CXCR3 receptor on intestinal epithelial cells. And that's one of the prevailing hypotheses in terms of pathogenesis is that the CXCR3 receptor will stimulate the release of zonulin zonulin will then trigger that paracellular leakage that you mentioned earlier. And as the gliadin passes through the laminapropria, then we see this release of IL 15 from the intestinal epithelial cells and that IL 15 is what's going to recruit those intraepithelial lymphocytes. And so that infiltration of those lymphocytes into the intestinal barrier is one of the Hallmark one of the Hallmark traits of celiac disease from the clinical perspective, as I'm sure you're very familiar with Marsh scores. For example,Let's back that up. Because that is a key, everything you just said. But I want my colleagues to understand this because as somebody who is a strong believer in intestinal permeability, aka leaky gut on Google, but intestinal permeability, from talking to my colleagues leading to other things, let's let's walk it back. You discussed how gliadin binds to CXCR3 which is fancy and everything but dumb it down for me really quick gliadin leads to this which leads to zonulin which leads to this so that I can tell my patients and my colleagues can tell their patients. This is this is the process of why I want you to avoid or to avoid gluten to avoid gliadin.So I guess what you would tell patients is basically that their intestinal lining is extremely sensitive to this individual protein and when they take in this protein their body is it's it's mounting a response almost as if there is an invader an immune response to this protein if that is helpful.And you showed it is helpful because zonulin is something that I look for I actually found a lab that can order that so I can look and see, okay, I believe that you do have some intestinal permeability. We know that infection, bacterial overgrowth, and in talks that I've given, I say that high ingestion of gluten does this lead to increased zonulin. I didn't have a mechanism how it did, but now we realize it. You just explained it. So it makes it like every time you dial it down a little further, you're like, no, I believe it more now. So I've been saying that for a long time. Yeah, that is really cool. So yeah, so you, in your science have shown that zonulin leads to intestinal permeability.I was not the person to discover that. But there there is a I believe...You have the opportunity to own it right now. Nobody else has stuck their flag in it.I'm not gonna take credit.You can credit for everything you want. Until somebody else calls me right now and says "that's mine!"Brilliant, man. Yeah, yeah, there there is the mucosal immunology lab at Massachusetts General Hospital, Dr. Alessio Fasano who headed that work. Yeah, I would love to take credit for it, but I think that would follow my career in a negative way.Alessio Fasano basically, I would fly and just listen to him lecture and then leave the whole rest of the, you know, the lecture yet Alessio Fasano is one of my heroes. So yeah, for sure. That's that that's why I thought it was funny. If you claimed it. He seems to have relaxed a little bit over the years, he needs to get back at it. That is awesome. Um, let's talk a little bit about the whole section that you have on treatments, because you did a great job of summarizing different treatments that pharmaceutical companies different people have tried to do. I'm very keen to well, anyways, I'll let you get into it, because he did a great job of reviewing all of it and to show what has promise what doesn't what's there, what has failed in clinical trials, before we even begin to discuss the polyphenols because then the rest of your paper is about, I believe that this is probably the best mechanism. So do you remember some of the stuff that you have in the paper about a few of the different mechanisms that different pharmaceutical companies are looking at?Yeah, for sure. So they can kind of be broken down into two major classes. So I think of them really as patient focused versus protein focused and the patient focused therapies are going to be kind of your immunomodulators things that are affecting the individuals the individual's immune response, that inflammatory cascade through for example, Nexvax was a vaccine that was I think it got to phase two trials and then eventually was, was shut down. We have larazotide acetate, which is a zonulin inhibitor. That one is in I believe, phase three trials now, which is pretty exciting. And those that target the immune response. I also I have to mention my favorite, which is the hook worms. So a hookworm infection can actually mediate immune responses, then take down what would be this overactive immune response and celiac disease, immunosuppressive effects of hookworms have been.So we have looked at trying to use worms for Crohn's disease for the same for the same reason. How does it do it in celiac disease?So in celiac disease, it just dampens the immune response. And what they've shown is that in vivo, individuals who've been infected with hookworms have a decreased IL 15 release upon stimulation with gluten.Interesting. That's the thing where we always say that in third world countries, you don't see autoimmune diseases. A lot of us argued that as to why. Yeah, so that's probably my favorite that I haven't done. But then we have the the protein focused therapies, which I think the most notable are the enzymes. So if you're orally taking in an enzyme that will help break down gluten further, that's one that's been shown to be effective, also some antibodies that will bind to gluten and prevent its digestion. So it's kind of a similar mechanism to what I talked about with polyphenols and those protein focused are basically going to either break down or further sequester. gluten from digestion. .Yeah, you got into a little bit about how these proteins bind and how there's different mechanisms with polyphenols really quick. The nexvax, was that, was that ImmusanT? Do you know the company that was doing it?Yes,So years ago. So Bob Anderson is a guess is a PhD gastroenterologist out of Australia. I had hooked up with him when we were just beginning the whole concept of using polyphenols to treat IBS. And, and it shows how difficult it is to really take a concept. And take it all the way through to something you can get through the FDA because it was like 8, 10 years ago that he was working on this, and it started a company. And then when you said that I was reading your paper, I was like, oh, it didn't work. That guy put his life. I mean, put his heart and soul into it. And so shout out to Dr. Anderson, who really kind of, I think, hopefully his next version will be able to do this. So we can have a vaccine. Everybody's talking vaccines right now. So we'd love to have the old vaccine.It's a hot topic.That's awesome. You wanna ask anything about that? About all of that? Yeah. Man, you must be tired. Thanks, Ken. That was awesome. No, I find it incredibly interesting the way that you've had this pathway to to figure out what proteins are the biggest threat. I was surprised from what you had written specifically about hookworms. And I was just thinking about the, you know, those who who wouldn't have an inflammatory issue because they weren't wearing shoes. Isn't that how you transmit hookworms is through the soles of the feet?I do not remember my parasitology right now, do you know Charlene?I'm not sure I'm pretty sure they were orally administered, at least in the studies.I'm sure in the study they were. My version was the was the old version. We're gonna see if hookworms work here, everybody take your shoes off. That vat right there has placebos or that vat has hookworms just jump around and see what happens.So remember before we recorded and started this episode, we told you we'd leave all of the all of the mistakes in that joke didn't work. And that's fine. It happens occasionally.But I think it's really important because leading up to that you're discussing all these different ways that pharmaceutical companies are trying to do it and people are trying to figure it out use it's really not always like the hookworms oral ingestion, not soles of the feet. But I do think hookworms happen because you get exposed to it. So then this is when you propose why polyphenols. So now this is the peeling back where now you're going to discuss polyphenols. So looking at all those different mechanisms, why do you 30,000 foot view, why do you think polyphenols will be beneficial, and then we'll dial down to the different steps, you've got some great charts and steps A through F on how it works and some incredible science on everything. So why did you think the polyphenols would do this in the very, very, very beginning?So in the very beginning, it seemed like there was probably a pretty good chance that polyphenols would be able to be beneficial because we knew from those studies with using gluten as a fining agent in wine, that there would be an interaction between gluten and these polyphenols. And then we have sort of this added benefit of knowing that polyphenols are generally safe, you know, people consume them every day, as long as they're eating fruits and vegetables. And we know that they have these other beneficial effects for so for example, they have these antioxidant, anti inflammatory effects that are occurring when these compounds are not interacting with protein. So we know that they're already generally a pretty good thing. And protein polyphenol interactions are just kind of this natural phenomenon that we see all the time in many different contexts. So just starting out it seemed like it was probably going to be a slam dunk.That's awesome. All right now, oh, where was it page for this page 19. That little picture sums ups a lot of important things that little picture right there sums up about 15 or 12 pages of material. So this is the your graph here shows stepwise why you can demonstrate how a and then we'll get into this after you go through this but a large polyphenolic compound with more branches can do some of these things. So this is kind of the steps A through F on how these polyphenols may help us deal with gliadin. So on your first part right here, can you please explain the physical sequestration of native gliadins.So with native glutens that's going to be your gliadin before it interacts with any of your digestive enzymes in your gastrointestinal tract. So that would be the form of gliadin, that's going to show up in, for example, a slice of bread. So these are going to be higher molecular weight proteins that are fully intact and haven't been digested at all. And these are able to interact with polyphenols through a variety of molecular mechanisms. So we see a lot of hydrogen bonding, we see ring stacking, one of my earlier papers really gets into the weeds in terms of the types of bonds that are formed from but we see these interactions and the formation of this precipitate and solution. So if you were to combine a solution of polyphenols in a solution of gliadin, you would see it actually form a solid and start to fall out of solution, which is a pretty good indicator that there is a physical interaction going on. So it's kind of the first step. And we see that also with gliadins that have been digested by pepsin and triptan which are two digestive enzymes.What what polyphenol did you start with specifically, what type of polyphenols?So I specifically first was interested in Epigallocatechin Gallate, which is the primary catechin found in green tea. I was interested in egcg because because of its prevalence in green tea, and we know that it has all of these other beneficial effects, it was being studied, in terms of its anti obesity and anti inflammatory effects by another group at Penn State at the time. So it seems like the one to target and some of my later more applied work used green tea extract. So that would also combine other types of catechins and smaller phenolic compounds.Nice. We're gonna get into that and a little bit here. All right, then in your beautiful little graph here. Step two hydrolyzed gliadins.Yeah, so what I just mentioned hydrolyzed gliadins, that would be those which have encountered pepsin and triptan. So breaking those proteins down into smaller digested fragments. And we see the same sort of precipitation forming the same kind of haze formation when we combine those in solution.So basically, we're talking about a larger gliadin molecule versus a smaller one. Regardless, the polyphenols are going to suck up, grab it, and sink down to the bottom. What was that called in wine again? Would you consider this fining also, even though it's not in the wine industry? Can we use theIt is the same molecular mechanism. But it's, I mean, fining I think, refers more to the processing. But we do see protein and polyphenol interactions similar to this in a lot of different areas of science. So again, in wine, because it's sort of the root of this project, we see interactions between small prolene rich proteins and polyphenols in astringency. So like if you take a sip of red wine and you kind of get that drying sensation on your tongue, that's actually the polyphenols from the wine, precipitating your salivary proteins, which are also rich in prolene.So that was I always wondered that also. So okay, so quick question, which is interesting. So if it well, I'll save it for later because I want to go through the mechanisms first. So that's two mechanisms, but I got so many questions for you related to all this stuff. Then there's the aspect of digestive enzyme inhibition.Right. So um, this is actually I think one of the one of the really interesting parts of this study is polyphenols have been noted for anti nutritional properties and the prevention of protein digestion, and a few different studies in the past, showing that individuals have a high intake of polyphenols, they actually can sometimes have issues with protein absorption. So one of the reasons is the direct interactions with protein like we just mentioned, between the polyphenols and gliadin. But another is the fact that these polyphenols can directly inhibit the action of digestive enzymes through either binding directly to the enzyme and kind of changing the shape of the enzyme preventing it from being able to preventing it from being able to hydrolyze its substrate or binding in that same binding pocket for the enzyme and preventing the substrate from even getting in.So that's fascinating. So there's there is a little bit of a debatable thing because when working with scientists in the cattle industry, there's actually some data to show that when you give sheep and cattle large like tannins, they actually have improved nutrition and but they're ruminants and then people try extrapolates the ruminants over here. And then we've worked with some scientists that have actually said, well, the binding, if it binds to the protein, not necessarily the protease or the lipase, or whatever pancreatic enzyme it is, that when it gets since the actual large tannin does not get absorbed, it stays intraluminal, the body can digest the protein off, and then the tannin keeps going. So there's it's interesting because I think that there is some debate a little bit where like you have people like Anna Hagerman that are talking about how it can be an anti nutritional thing. And then you've got these other people in sports nutrition saying no, actually, you can improve the overall nutritional value of foods by taking it with a polyphenol. And so it's it's a fascinating area. And I think that it's kind of a moving target we have seen in clinic in my clinical practice, and in the studies that we've done, we've seen beneficial results using polyphenols. And I think that's why it can do some different things like work as a fasting mimetic molecule and things like that. That's That's really interesting. I did not know that it has the potential to bind to the digestive enzyme. I had not come across that before wild. So...Yeah, because enzymes are proteins. The next one, improved barrier integrity and transport and decreased transport. So um, there have been some studies that have shown in individuals with leaky gut or intestinal permeability, that polyphenols are able to just directly affect intestinal barrier function. And I showed in one of my studies actually, in our untreated controls that we saw an increase in barrier integrity, when we just use green tea extract, compared to the control, so in the absence of gliadin, we still saw an increase in transepithelial electrical resistance,Improved leaky gut, do you have a mechanism for that when it's not related to gliadin?Um, so in terms of improving it, when it's not related to gliadin, it's most likely just related to the inflammatory cascade. And, you know, the gut is kind of just always in flux, and always producing, you know, interleukin 6 810, just everything and kind of mediating that response, I think, can expose potentially some underlying permeability, that it can then reverse.I love that you say that because we talk a lot about other things that create intestinal inflammation like high fructose corn syrup, polyunsaturated fatty acids, like soybean oil, and things like that, that have been shown to create an inflammatory response. So you said something really interesting. We're talking about gliadin here, but you this also shows that it can help with the leaky gut, intestinal permeability, whatever you want to say, when it doesn't even it isn't related to gliadin it can actually do that related to the inflammatory cascade, and we talk a lot about inflammation on the show all the time. inflammation is good when you need it. Bad when it stays there all the time. And unfortunately, our diets I think that we tend to keep it inflamed, if you eat the typical, you know, American diet, the sad diet, you're gonna you're gonna have an inflamed gut, you need to protect it. Definitely. And you haven't gotten to zonulin yet have you?We talked about Zonulin a little earlier.No, like during during the cascade that you had written down with your hand. The reason why I say that is because you had long before in conjunction with the leaky gut protection. You had mentioned that zonulin contributes to leaky gut. And since we had mentioned it earlier, and he hadn't put it on there, they're probably controlling the, or keeping the decrease of zonulin, after having enough polyphenols would also lend toWell, now that he brings it up. So you wrote that gliadin binds to myd88, which ultimately releases the zonulin. So does it prevent the binding to the myd88? Is that how it prevents zonulin from from being released?We don't know the precise mechanism in terms of what interactions it's actually preventing. So where it's really targeting that inflammatory cascade, it would make sense based on our data, that the polyphenols are sequestering the gliadin and preventing it from binding to anything else. But in terms of studies where we actually pinpoint that mechanism, those haven't been done yet. So I think it would be really interesting to do some of this either in vitro or ex vivo if we were able to get tissue cultures to see how that affects really the zonulin release because that's kind of the the linchpin in that mechanism.So that's fascinating. So I've had you know, I've always I treat a lot of small intestinal bacterial overgrowth SIBO patients and I will check them and they will have increased levels of zonulin. I assume it's related to the bacterial inflammatory cascade and we treat it and it goes down. Treat them with Atrantil and it goes down. And I'm assuming it's I got rid of the bacteria, but you just brought up something interesting. There may be something more nuanced going on.Or SIBO I mean a lot of a lot of different options.Yeah. So that's, I think that's, that's another angle. It just shows how much I think there's so much cool chemistry, cool physiology, cool applications of this, that you're that you're really tapping into. And you're, you're bringing up your own questions, you're gonna have a long career chasing your own thoughts. So. And then, we already talked about the anti inflammatory activity, NF Kappa beta, and things like that, that you basically discussed, which is the overall decreasing of the inflammatory response. And then the final one that you discuss in this in this in this figure is the transglutaminase downregulation. Can you explain that that one I was struggling with.Yeah, so that actually is from a really recent paper by a group out of Louisiana State University. And they found that when treating intestinal cells in vitro with Coco polyphenols, they saw a down reveal a down regulation of tissue transglutaminase. So when we have this exposure of gliadin, to our intestinal cells, transglutaminase is released kind of as a response to epithelial damage. It's an enzyme that is found in everyone's body that's associated with wound healing. So when the intestinal when your intestinal barrier is kind of infiltrated by intestinal epithelial lymphocyte, intestinal lymphocytes, sorry. When you see that infiltration, and that damage that's occurring, that's when transglutaminase is released. And what they found in vitro was that we're not seeing that release of transglutaminase when polyphenols were added to that culture.That's super cool. You probably don't have a direct MLA on that yet, but it's definitely been noticed as a as a decrease. Is that what you're saying?Right, yeah.Okay. Now that that's very, very cool, though. I don't think I'd ever heard that before at all.No, that is really cool. And the mechanisms that how you're going to all of this is just absolutely incredible. Alright, so let's dumb it down real quick, for me. I need my prolene and my saliva. And now I understand why, so can you tell me how fat...so like if I eat a ribeye and then take a big, bold Cabernet? Why the Cabernet doesn't have that astringency while I'm eating a fat I've always wondered...Yeah, so fat will coat your tongue. And it's basically creating a layer between the proteins that are in your saliva and inhibiting that binding.So it's, it's making the tannin just slide over the prolene is what you're saying?Um, yeah, you could explain it that way.Well, that's, I'm gonna explain it that way to myself. I'm not gonna get more complex. I'm just gonna go you're just doing this to let it slide over. I liked the way she said, "you could do that."Alright, so in theory, we have done I mean, it's, it's not fining because it's the but but you need to come up with your own term when when polyphenols bind gliadin and sink to the bottom. So shining, Charlene fining and it's Charlening. So when you're Charlening gliadin down in there and then if I take so if I put a bunch of gliadin in this cup and then I put a bunch of polyphenols in there and it it Charlenings it down Charlenings, can I turn that into a verb? Yeah, you did. You just did!So when I'm Charlening the gliadin to the bottom of the cup, and I mix it up and I swallow it. This is the other concept I'm trying to think of does the body then it goes down. I don't feel the astringency because it's already bound to the gliadin or whatever. It's I'm not getting that but will the body then break off? Will the enzyme since the polyphenol is tied to the gliadin? Will my body break off that Charlening molecule? In other words, will it can it still digest the protein that is attached to it?So in terms of whether it can still digest the protein, our data says that it will not so doing an in vitro digestion of polyphenols and gliadins that have been sort of pre combined before all of the pH fluctuations before the introduction of pepsin and trypsin. We've found that that complexation will prevent The digestion of gliadins of native gliadins. And it will prevent the formation of the smaller molecular weight fragments that stimulate the inflammatory response.So since it binds so strongly to the prolene, glutamine aspect, if you have a protein that doesn't have that, do you think that there will be less affinity and it will come apart?Well, that's definitely something we're interested in, in looking at. Now that I have some grad students working on this project, we're really interested in seeing how kind of the matrix effect of everything else in the gut can affect these interactions and affect the stability. So one thing that I think suggests that we'll still see some success with this nutraceutical treatment is the fact that polyphenols generally have a greater affinity to bind to proteins that have a high frequency of prolene. And the high frequency of prolene that we see in gliadin is is fairly unique. We don't really see that much in other food proteins. So it's something we'll need to investigate, but there's definitely a chanceWhat are some other high prolene foods that we typically eat?High prolene foods that we eat? I think you got me on that one. But in terms of the kind of major food proteins that we study, in the lab, so I remember doing some sort of preliminary work with like beta lactam globulin and some casein when I was in grad school. And just to kind of look at precipitation, those definitely have less prolene than than gliadins do. In terms of others that have high amounts of prolene, I'd have to look into that. I remember looking once as to why everybody did why there's a lot of soy issues. And I did see that soy has high prolene compared to other proteins. And so I'm wondering if that's one of the reasons why a lot of people have issues with soy also. I don't know,I that's definitely something that's that's worth looking into. Because it is the high prolene content that kind of gives gliadin that unraveled structure that makes it difficult to break down enzymatically. That's definitely something to look at, but not something I have I've heard or read.You've been slacking CharlenePoor CVs only 17 pages long.You know, you sit there you, you come up with the term Charlening, and you're just resting on your laurels making money off that Trademark. All right. Now my favorite, favorite part of this whole thing you said in your article studies into mechanisms have shown phenolics with large branching structures with greater potential interaction have greater affinity for interacting with gliadin. So that's something that a lot of people don't really understand is that these polyphenolic compounds come in varying shapes and sizes. I this is I'm setting this up, because the scientists that we've been working with in South America, the quebracho Colorado is one of the largest stable polyphenols that we the original research I was doing is because it's both acid stable, and its basic stable, which means it can stay intraluminal in the in the intestine, and then the scientists we've worked with one of them in an in vitro digestion showed that when this becomes fermented, in other words, with our microbiome, that it actually she did a gas chromatograph and showed all these different molecules that came off, one of them being egcg, and other one being quercetin and another one being rutin. And you're like, holy cow, wait a minute, these large building blocks actually have all these smaller phenolic molecules in it. And all the studies have been done on smaller phenolic molecules, because the prior studies were done on that. And you're going to grab a molecule that's already been done. I forgot his name but the but the gastroenterologist that uses egcg to look at ulcerative colitis, and then that guy, because somebody else did it, and that's the proof of concept. What is really interesting is this whole science is using these large if I gave you the largest, most hydroxyl bond, you know, molecule, would this be the thing that would work that I guess your paragraph implies that,Yeah, so it's actually really interesting. And some studies that I've completed that we're kind of working on getting out there at the moment, sort of take this idea of size versus actual shape. So when we talk about polyphenols and their and their structure, we're taking into consideration the molecular weight, but also the branching like you mentioned. So if we compare molecules like Thea Flavin, which is found in black tea versus egcg, which is found in green tea, they have relatively comparable molecular weights. But egcg has this hydroxylation that almost makes it from like arms. And it has this more flexible bendable structure.You lost me though. Would you show that one more time? What does it do?Yeah. So it kind of has these arms that are almost able to wrap around a protein whereas Thea Flavin has, if you look at the structure of this Benzotropolone ring, which is just as large, bulky, sort of ring structure, and it doesn't have sort of that same flexibility as egcg has. So even though Theo Flavin actually is a little bit larger, egcg is able to bind better. So it really comes down to the structure dictating the function of the molecule, which kind of brings it to my lab and my fascination with all of this the food structure and function lab. Yeah, figuring out how structure can affect the function of these molecules with...Oh! That's why you called it that. Food structure and function. Your website. I was like, that's an odd name for website, foodstructureandfunctionlab.com. And now it makes sense, not just the food, or the structure, but it happens to be that the two combine to make a function.Those are really interrelated and biochemistry andFood structure function lab. Sorry, I want to make sure everybody hears that food structure, function lab.comStructure and function lab. Okay just say it one more time.Foodstructureandfunctionlab.comThere we go. Sorry to interrupt. I just want to make sure that peopleNo you're fine. But yeah, conceptually, that is something that I just think is so fascinating how the structure can really affect the function in terms of health. SoSo as a, butt doctor, the thing that's going to blow, take that all up to another level is how the microbiome is involved with us, then we're, like, everything you're doing is fascinating. It's so cool. And then you start fermenting it and seeing what happens, and some pretty incredible magic happens. SoRight, yeah, so fermentation, but then some of the work that I did, during my postdoc at Rutgers University, we were looking at alternative mechanisms for polyphenols to affect the gut microbiome, because we saw with, um, I believe it was cranberry polyphenols, as well as Grapeseed, extract someone before me, and found that supplementation of those polyphenols to an individual with diabetes resulted in the increase of this growth of akkermansia ophelia. And so we're trying to look at how this can why this happens, you know, like, what is the mechanism? And so one of the things that we really got interested in was the potential for polyphenols to act as radical scavengers in the lumen. So whether they're being broken down by the gut bacteria, whether they're scavenging radicals, whether they have an antibiotic capacity, I mean, there are so many options, and it's so fascinating. So, yeah, sorry to go off on that tangent,TThat's pretty much the world I live in because I see my goal. What we have seen through fecal studies, actually, is that when my patients take a either a diet large and polyphenols, or they supplement with Atrantil we have seen an increase in microbial diversity. And then once you have an increase in microbial diversity, you start having different species of bacteria which can do these beneficial things like the anti diabetic, anti obesogenic and then you have the anti. And then people are now looking into that. And that's sort of this whole new field of science called the postbiotics. It's like, what does the so we're almost describing that these become prebiotic, like, we're just something that is not digested and then your own microbiome, but what we're seeing is, is that it's not a one to one, you have to have a diverse microbiome to get the full benefit of these polyphenols. So you can have the structure and function but you also have to have the ability to produce these postbiotics, like have you ever heard of a molecule called urolithin urolithin a urolithin B, you know, things like that. Lactic acid gets, you know, kicks off and we know that that helps, you know with apoptosis and Mitophagy and there's a lot of there's a lot of stuff to uncover. This is a lot of really cool things. What do you think? Alright, so just sum this up. Sorry about that. We covered so much material. So to sum up your whole paper here and in just a couple sentences, because there's a lot that we just talked about, and I want to hear it in your words. How would you describe what you just what we just talked about in just a couple sentences?So overall, we are focusing on developing a nutraceutical approach to treating celiac disease via the natural phenomenon of protein polyphenol interactions, and keeping gliadin from being digested and being recognized by the immune system.She did it in one sentence Ken. Yeah she did. Wow. All right, what's your lab gonna do next? What are you guys working on?We are continuing to pursue this project. It was kind of on a hiatus as I did my postdoc working on a different project. But now that I have my own lab, but I have a couple of graduate students who are really targeting that sort of structure and function angle, we're looking at extracts from different polyphenol rich foods for their ability to basically elicit the same effects that I observed with green tea extract. And we're also trying to kind of target those downstream mechanisms that I discussed in the paper. So what is the impact of polyphenol supplementation on for example, the activity of tissue transglutaminase? What is the impact on the recognition of these proteins by antigen presenting cells? I'm kind of trying to go downstream and sort of look at this. The potential of polyphenols from really every angle of celiac disease.That's awesome. You said you have two graduate students working for you right nowI actually have four right now. Yeah, I have a few that are working. I have two that are working on the celiac disease project. And then two more that are working on another project based on protein polyphenol interactions. We're looking at using novel plant proteins as delivery systems of anthocyanins. Oh, wow, that's awesome. Can you do me a huge favor and subtle debate between me and Eric? Can you just take two of those and have one of your graduate students swallow hookworms have the other one just walk around on hookworms to seeWe haven't even had a hiatus to have this debate.I have a student who an undergrad who really wants to work in my lab, so I'll pitch that project to him.Poor undergrad doing anything. to get into graduate. Hookworm internship. Nice. Well, Dr. Charlene Van Buitin. Thank you so much PhD as Assistant Professor of food science and Human Nutrition at Colorado State University. I can't thank you enough for coming. Oh, yeah. Without I want to repeat your your website foodstructureandfunctionlab.com correct? Everything will be listed in show notes will have links to your study as well as your own personal website and Ken, any closing remarks?Your social media hashtag, there's no way you're as smart as I am. Do you have any social media or anything? Do you want to get out there? I'm on Twitter, cbvanbuitin. If anyone has questions or is interested, I don't share that much science on there. Mostly insight to working in academia. But yeah, that's that's really all I'm on.So if you want hard hitting political opinions. Go to her Twitter account. Not at all. Thank you so much. Don't go anywhere once we wrap up the show. But gut check project fans, that is going to be episode number 52. Be sure and check show notes. So you can connect with Dr. Van Buiten. And, again, if you have anyone in your life or yourself suffer from celiac disease, we think that this information could be of just huge, great consequences for you and your family. 100% and this is why we do this this is we get an opportunity to meet brilliant people like you, thank you for taking the time to do this. And hopefully this will this will get somebody to call you lab. Hopefully we'll be able to do some sort of collab, I would love to collaborate with your lab. We can we'll talk more about that. But maybe another scientist goes, Oh, this is a little piece I was looking for. This is how we help each other as a community. I'm a clinician, you're a bench researcher. I'm going to apply whatever you tell me and see if it works and just thank you for doing everything that you do.Thanks. Thanks so much for having me.Absolutely. That's episode number 52. We'll see y'all next time. Like and share. See you next time. Bye bye.

Anti-Histamines, Probiotic Fart Quality, SIBO After C-Section | THRR064

Play Episode Listen Later Feb 5, 2021 39:19

SIBO Post C-Section, Colonoscopy Prep, Quality of Intestinal Gasses on Probiotics, Practicality of Bulking on Keto, Thoughts on Anti-Histamines? Make your health an act of rebellion. Join The Healthy Rebellion Please Subscribe and Review: Apple Podcasts | RSS Submit your questions for the podcast here Show Notes: News topic du jour: https://www.theguardian.com/world/2021/jan/27/china-starts-using-anal-swabs-test-covid-high-infection-areas 1. SIBO Post C-Section [11:39] Jaimie says: Hi Robb and Nikki! Love your passion and information for this podcast! I'm looking for some help with diving through the endless research and information on SIBO. A little background: I'm 34, and in January had my second baby. This time around I had to have a c-section due to a previous abdominal surgery. I have followed a pretty holistic lifestyle for the last 10 years, and typically eat a paleo diet. I couldn't tell you the last time I had antibiotics until this surgery. A week post op my incision ended up getting infected, and I took another round of antibiotics. I'm not one to take pain meds, but did rotate Ibuprofen and tylenol for pain post op. Of course, this all reeked havoc on my gut. I never had gut issues and started to notice a lot of things changing postpartum. A month ago, I saw a functional med NP who did some labs and I did a stool sample. A few weeks ago we reviewed the results. I have sibo- methane predominant, as well as H. pylori... there were other things like E. coli, parasite(EEEK!), and other digestive enzymes that were off. Basically, the NP said that for right now because I'm breastfeeding I can't really take anything for the SIBO, but to try and just focus on my diet. Being the perfectionist that I am cannot settle for that :) I've been researching some things on SIBO and came across a podcast by Kresser. They were discussing the supplement ATRANTIL. They discussed some case studies on it and the positives, but I'm curious if you are familiar with this product and what the research says? Also, What are your thoughts on taking this while breastfeeding? Of course it hasn't been studied, but if Nikki had SIBO what would you do? :) Thanks so much and keep up the great work! 2. Colonoscopy Prep [15:04] Eric says: Robb and Nicki, Thanks for all the hard work you guys put into this community. I have been following Robbs' work for many years now. I did stop eating a whole food diet slowly over the last 6 years. I am getting back into it and love how I am feeling and doing. On to my questions: I am scheduled to have a colonoscopy next month. Do you have any recommendations for the prepping for the procedure? I was thinking about using LMNT instead of the sports drink recommendation would this be ok? Also, any recommendations on things I can do after the procedure to improve my gut? Information about me 40 years of age 5' 10" 225 pounds 3. Quality of Intestinal Gasses on Probiotics [17:59] Michal says: Hi Robb! I've been a huge fan of your as well as your podcast for some 4 months now. Listened to almost all archive talks of yours and read Wired to Eat. The only reason I haven't yet subscrive to the Healthy Rebellion is I'm a loner and don't really dig communities. The reason I am writing to you is the recent finding of mine. I had a bad gut microba for years. I didn't need any hard research on it, neither did I test it. I just knew it was bad by how I felt all the time not to mention how I felt after eating most things. Bloated, gassy with impossible acidic reflux and often loose stool. I knew I needed to improve my gut health and invested in probiotics (namely NOW's 25B portion). On top of that I also bought myself pickled veggies: a mix of salads, pickled kimchi, pickled carrots and whatnot. To my surprise I am way less bloated, less gassy and with firmer stool. The biggest surprise, however, is the quality of those gases. I am not a fart expert, by any means, but the change is visible. Until I picked up massive ammounts of probiotics, my gasses were frequent, smelly (af) and kind of soft. Like a 'puff' sound. Now they are less frequent and less smelly but more pronounced. They are shorter in duration, a bit louder and, sort of, trumpet like. It feels great. My guess is the last thing you want in your email is reading about some guy's in Poland gasses but I thought you might have some insights into this. Is it normal? How come my gasses changed just by adding microbiota and live bacteria to my gut? I'd love to learn more, especially since I heard that gut is being thought of as our second brain (sometimes the first) due to its influence of and regulation over, well, basically everything. Looking forward to hearing from you. Cheers from Poland. Michal 4. Practicality of Bulking on Keto [27:27] Alex says: Dear Robb & Nicki, -I am male -29 years old -5'4'' -probably around 11% body fat (at the time of writing this) -relatively strong: can squat and pull a little more than 2x bodyweight, strict muscle-ups, etc., etc. My question is about the efficacy of bulking with a ketogenic diet. I am not currently following a keto diet. I have never done any kind of glucose monitoring, but I'm assuming that I tolerate carbs pretty well because I would not feel noticeably worse if I were to consume a ton of carbs. Now, I would really like to get as jacked as possible, and I hate the traditional bulking and cutting cycle. Robb frequently mentions the Ketogains folks, and I know Luis Villasenor talks about this idea of "gaintaining" - or continually building lean mass, which sounds way more preferable to me even if the progress is dramatically slower than a conventional carb-heavy bulk. I would love to just stay lean year-round and not have to do maintenance and cutting cycles. I understand it is also perhaps a little more challenging to bulk on keto because the food is much more satiating. I've been using the RP Diet app for the past couple of years and I like it a lot actually, I'm pretty happy with my body composition - but if this "gaintaining" thing is a real option I would be seriously interested in trying it. I follow Power Athlete's Jacked Street program and I know John has this "you don't need more carbs than you need" philosophy, but he has also said carbs are pretty much essential for bulking, and that dude knows a thing or two about bulking. With the conventional bulk/cut approach I often feel like I'm taking one step forward and then 9/10 of a step back. It just occurred to me that I think I forgot to include my bodyweight in my initial question. It's currently about 141 lbs, don't know how relevant that is. My goal is to get down to about 10% body fat so that I can attack this bulk with everything I've got. P.S. - I LOVED the Salty Talk on the Great Barrington Declaration. I do find what you guys do to be valuable and listening to you on a weekly basis is extremely cathartic. You two are the voices of reason in this absolutely insane time we live in. You've mentioned the mental health consequences of this Covid lockdown many times and I don't know that I could have managed without this podcast. Thank you and keep up the amazing work. XOXO, Alex 5. Thoughts on Anti-Histamines? [34:35] Craig says: Hey Robb and Nicki! A couple questions on anti-histamines (Benadryl or Zyrtec) for allergies - do they have broader effects on reducing inflammation? Is there a danger around taking antihistamines regularly? Thanks in advance! Craig https://journals.physiology.org/doi/full/10.1152/physrev.00043.2007 https://www.healio.com/news/pediatrics/20191116/antihistamines-part-ii-longterm-adverse-effects#:~:text=Commonly%20used%20first%2Dgeneration%20antihistamines,the%20risk%20for%20developing%20dementia. Share the episode! If something in this show helped you please share the episode with your friends! Sponsor: The Healthy Rebellion Radio is sponsored by our electrolyte company, LMNT. Have you tried LMNT electrolytes yet? If not, this is the time to do it. Until January 31st, 2021 you can get a FREE 8 count sample pack (just pay shipping!). You’ll get: 2 sticks each of citrus salt, raspberry, orange, and RAW unflavored. Click here to get your free LMNT sample pack Transcript: Download a copy of this transcript here (PDF)

Angry Brains and Conflict

Play Episode Listen Later Feb 3, 2021 57:32

0:01 Hey, gut check project fans and KB MD health family. This is Eric, I'm here with my awesome co host, Dr. Kenneth Brown. And this is Episode 48. I don't have a clue what we're gonna talk about.0:12 Well, I think that Okay, so if you did not see Episode 47, we put a lot of work into that one. Yeah, we've gotten a ton of great feedback on that. And it's just the beginning, because because of that episode, we've been contacted by a lot of other scientists, a lot of people. And we're gonna be having a really special PhD on to describe her research soon. And it's, you know, thankfully, it's pretty cool. Yeah, it's0:34 really, really cool. We actually got a lot of feedback not only in the traditional sense, thank you all for who've been emailing in and messaging. But the two patients who came through and watched it right before we scoped them, I was impressed to how many of them tried to do what you did to me and made me list everything out. And so that was that was pretty interesting. So0:53 just a recap of 47 it was important because we've uncovered a lot of important research showing how the polyphenols like polyphenols in atrantil can actually help your innate immune system. And it's, it's the tip of the iceberg because I've been contacted by out both allergist epidemiologists, some PhDs going wow, that is exactly what my research is in. I'd like to talk about it more.1:16 What about just this morning, we had that discussion with somebody over in the UK who is specifically utilizing guess what polyphenols for athletes and elite athlete training. Never met the guy before has an incredible program. What do you think of that? Oh, that's1:31 great. It's actually Aiden Goggins. And he he wrote the cert diet, which is the I believe it's the diet that Adele lost all her weight on and it's all about the benefit of polyphenols turning on these sirtuin pathways. He's he agreed to come on the show also great guy super smart. That was awesome hanging out with him this morning. So what's going on with you? Let's let's get let's make this more casual this time. The last couple of podcasts have been so intense with the immune system and stuff. Let's change it up a little.1:56 Yeah, man. I chatted with gage this morning. He scores out of tech he's loving School, which is great. And you know he's he's enjoying his time as a freshman. His most college kids who are freshmen should be doing Mack is in midseason basketball. He loves it. He just He scored his 106 point where this basketball team is last week. He's super pumped about that. Okay,2:20 let's let's clarify that. So he scored his 106 documented point or he scored the 106 I2:25 scored the 106 which is the high watermark for his current code. That's awesome. That's awesome joints. He joins his brother who was the first person to push a coach over 1002:34 Yes, that's awesome. So the reader brothers doing proper to the basketball team.2:39 Their dad's terrible. I know. I got a shiner got a little shiner. Here you go look at the camera here. Yeah, look at the mirror image of me. Yeah, we're doing little remodeling on the house. And unfortunately, the middle of the night I tripped over a box and face planet. So as I was telling my patient I walked in and we're gonna put him to sleep. And he's like, Whoa, Doc, he's like, do a get a little tussle. And I'm like, no. And he's like, well, it'll probably only affect your modeling career for a bit. And I'm like, Well, I'm actually a hand model. So that's why I protected myself with my face. Yeah, why don't you show that fingerand see how good of a handball you are?3:16 Well, I played I play the before picture and all hand model. A bunch of Orthopedic Surgeons jabbed me they're like, hey, yeah, can I use that in an ad?3:26 I specialize in ring finger. Yeah. We're gonna straighten it out.3:32 Oh, guess what I signed up for what? I signed up for the Wim Hof breathing. Wow, awesome. I'm doing the Wim Hof if you don't know who Wim Hof is, he's this crazy guy that has this incredible breathing course which we're gonna talk about that I read. I read James nesters book called breath, the site the lost science, and everything is all over there. Oh, dude, it's because we're all just like, Whoa, you can change your life by breathing. And that's what the Wim Hof Method is just breathe. And it's so I've been doing this every morning for we're going on two weeks now. And the problem is it also involves cold exposure. So every morning instead of waking up and doing my Yani coffee and warm hot shower, I'm breathing a ton and then jumping into a cold shower so we'll see4:16 feedback on it. Okay, well, just real quick, since I don't know where we're going with today's show. I'm just gonna go ahead and ask is this one of those things from Wim Hof where he is having you breathe in at a certain interval breathe out a certain interval so that you can achieve something and then it can you can you shed a little light on them?4:32 Yeah. So the Wim Hof Method in a nutshell is a cyclical breathing where you, you over inflate and then you exhale to atmospheric pressure. So you go above atmospheric pressure to atmospheric pressure. You do this in a cyclical way, almost like a wave and you train yourself to breathe in a cyclical way. And what that does is that increases your oxygen saturation of the cells decreases your co2, and I know where you're going because last time we I started talking about putting physiology, we ended up doing a whole podcast on that. Check out COVID episode three or four. But what that does is that actually raises your pH because the co2 retention will increase the pH. Okay. So in this book, in breath, I got really into that because we realized that in our stress society and the more stressed you are, we tend to shallow rapid breathe, which actually is the improper way to do it. So when you want to relax, you breathe six seconds in six seconds out, that should be the proper tempo. This is a different method. This is to supercharge your parasympathetic and sympathetic nervous system interesting. And then you do 30. In this case, you can do like 30 cycles of this. really deep breathing and then it on number 30, you exhale, and you hold your breath. So you and you time it and it's really funny because I'm following him on the course. And he's this very, he's been on Rhonda Patrick show and always been a me Joe Rogan. And everybody and so he's so funny, because he's the same all the time. I think he's always Wim Yeah. And so he's been on Ben Greenfield and stuff. And so he's, you know, you feel like this bond, because I'm like, holding my breath. And he's like, it's okay. You're good. You can do longer. You're,6:12 I mean, the guy is a physical walking experiment. He's done everything, especially when it comes down to this controlled breathing situation.6:19 Yeah, he holds like 20 world records and stuff. Yeah, but but it's all but it's all based off science. It's not like and that's what he tries to tell everybody. He's like, anybody can do this. So that's what I'm, that's what I'm going to experiment. We'll6:28 see if I can interesting. I'm curious how how they're explaining to lay people because that's probably what this is written for. From lay people all the way down to the science. So maybe that would be a topic that we will get into after you experiment with it a6:40 little bit. Yeah, 6:40 I'm really interested. 6:41 But we want to keep this episode light. Okay, this is just gonna be a fun, easy episode. Or we're just gonna relax. Gosh, I was sitting there with Dr. Ackerman in the office. And I got a quick question for you. Because uh6:56 have a quick question for me after talking to Steve6:57 Yeah, okay. Because it says cuz Stu, and I kind of disagreed on something. And I was like, Are you insane? We got in this discussion about carbonated water and he actually likes Waterloo over Bella VB. Like more like I couldn't even believe it. I'm like, Are you insane? Okay, well, wait, who's7:15 insane? He's insane for liking for liking Waterloo.7:18 Like how can you like Waterloo? Over Bell v. I mean, it's a apparently, well,7:25 I never questioned the fact that you are a doctor until right now. Because apparently, Stu is on the right side of history. And you're on the wrong side of history. 7:33 How can you even say that? I mean, the bubbles in this are more effervescent, the flavoring is better. I mean, I have7:40 a feeling that you're way more prepared for this talk than me. I'm just going to tell you that Waterloo kicks ass. Because I think Waterloo labor looks really cute7:48 is delicious. We can argue about this calories,7:50 no sugar. I don't know how many of these are crusher day, but I think they're awesome.7:55 I don't want to spend this whole podcast arguing about which carbonated beverage is better? I do I do have a real question for you. Okay, because I was totally forgot this. And I know that you and I've done this. Would you mind explaining to me? Because I know you're really like theoretical mathematics. Can you explain to me again, the Yang Mills existence and mass gap in mathematics?8:15 I would but it would take way too long. Okay.8:17 So I mean, you're super smart. And I realized that that would normally be just like a no brainer. I don't want to tell you that Yang Mills I love not being patronized back. Alright, so the whole reason for that set up. Was I I've been talking to a lot of patients and a lot of patients that have had COVID are having lingering symptoms and brain fog and things like that. And so you call them the the long haulers. Well, I see that all the time, because we see that people that have gut inflammation, end up having other things going on. So I was like, wow, you know, what, what, what is happening there? And then I started going down a little rabbit hole and Angie and I looking up articles and then you know, found this article where we thought Oh, when we initially when COVID first came out, it's like oh COVID infects the brain. And then I think you and I even discussed the possibility of the vagus nerve being a conduit where viruses can get up and it was all theory and everything. And so then I started thinking Wait a minute, if we end up with all these long hollers, what's the effect on the brain and then on the effect on the brain, I went down a little rabbit hole. And then I'm like, Well, wait a minute. If we end up with lots of neuro inflammation, how does that impact our psychiatric help?9:34 Health health? Yeah,9:35 because I'm, I really believe that we're gonna end up in another pandemic. So many people are suffering from depression and anxiety. And we may end up you may end up in a situation where if you had this infection, you could end up having a little bit more anxiety, OCD, different things. And so neuroinflammation then that got me thinking, Wait a minute, how does how will this affect spouses and families and things? Because divorce rates through the roof and I'm like, What if whoa, wait a minute, what if all this inflammation and the stress is leading to psychiatric changes, but not even something really tangible that you can sit there and label a DSM for diagnosis on? What if it actually affects your cognitive ability? And so then,10:20 let me just stop there. How could it not?10:22 Right? Totally agree, except this is this is a podcast where we try and make sense of things. Sure, that that are like that. So that's the rabbit hole that I went down. And now I'm going to bring it back. So what's interesting is I did I do want to discuss one article that looked at damage in dissected brains and people that died of COVID. Okay, and it's not as straightforward as you think. Okay. And then I started thinking, well, if there's the inflammation that's there, then I found an article that actually discusses neuro inflammation, psychiatric illness, followed by here's what happens in our brain when we disagree. And ultimately ending up on disagreeing takes up a lot of mental real estate. So that was a really long setup to ask you a mathematic question, to pretend like I tied up your brain arguing over carbonated water. I'm sorry. I was trying to figure out how to set up how we're gonna talk about today's episode, which is all about the brain. Okay. It's all about neuro inflammation, the brain and the fact that we're still in the middle of this pandemic. It really wasn't to bring you on the show and argue about water and then ask you a theoretical math question that I just googled 30 seconds before we came on the air11:35 live is fine. I'm just glad that I wasn't up for the challenge, either.11:39 You would have freaked me out if you would have noticed.11:42 It is would have been a random Google experience to be interesting. So if I understood what you just said that you're saying that we we probably waste far too many resources metabolically and over our brain trying to disagree with someone. Well, it's Yeah,11:58 that But let's get back to the inflammatory process. Okay, Episode 47 was the innate immune system. And it makes sense why we have all this inflammation. So I guess what I'm saying is, let's prepare ourselves for the possibility that more than the usual number of people may be behaving in a way that they may not, or they may behave an extreme way, because I just heard a podcast this morning on med cram, that he was discussing that an article came out on the online version of ama, where they were looking at these, they surveyed, like a bunch of 170 people, and a shockingly high number had residual symptoms, three to six months after actually being diagnosed with COVID. And of this group, they were all really mild. And so what, what we're now realizing is, is that we may end up having a lot of these young people that had really mild COVID end up having symptoms of they're just fatigued. Brain fog is super common. Sure. shortness of breath, it's common. Sure. So I think that we need to start preparing for this, I guess, is what I'm getting not only preparing for, here's, here's something that we don't know. So you just said three to six months. I mean, the the full on onset of COVID, still wasn't even one year ago. So if we're looking at that number, there, we're not even looking at like a threshold for this to end, right. Because we don't know that yet. There's not enough time has passed. We're saying three and six months, because that may just be as long as that infection has existed for13:32 that number of people. 100%. So13:34 let's jump into these articles. But I like where you're going with this. Because this is what I want to do is prepare for what makes sense of things before it actually happens. I'm actually quite proud of something. And I've heard this from several people that whatever, nine months ago when we did COVID one and two, I'm sure yeah, we actually still stood the test of time. Yeah. Because one of my friends was actually talking about this, the fact that he's hearing he's going back and having fun looking at podcasts at the beginning. And now it seems absurd the things that were saying, and I got scared. I was like, we're totally absurd. And we were actually pretty pretty spot on.14:10 Yeah, but I mean, I think quite honestly, in a lot of this has to do with the way that people who've communicate with us we, what we approach it isn't politically motivated. It's, I think that we're trying to always lean on what research says, and what research means. And so you can actually filter off, sometimes the stuff that's just noise. And that's what we try not to do here is deliver noise, we want to see if we can bring some context to what we think is real.14:37 So what I would like to do is let's talk about this and let's look at this from a future neuro inflammatory process. And it all comes down to one thing that we've said a million times on this show inflammation. Sure. All right, so the first article that I came across, and these are all obviously very recent articles, some of them just a few days ago actually. Study uncovers blood vessel damage and inflammation in COVID-19 patient brains, but no infection. So this is a surprise that they did an in depth study and how COVID-19 affects patients brains, and they consistently spotted hallmarks of what they consider damage in an MRI while the patient was living, okay. And then they ended up taking a sample of 19 patients that actually died, and then they did an autopsy on them, okay, assuming that they would find necrosis clots. Because we've been talking about clots during this, oh, you're gonna have these thrombosis factor five lied and gets kicked in, and then you're gonna have you know, clots happen. And so what they found was now the exact opposite was happening in these brains. What they did is they found these bright spots contain blood vessels that were thinner than normal blood vessels. Yeah, they gave up integrity, didn't they, they gave up integrity, they had leaky vessels. And this appeared to leak proteins, like fibrinogen, the brain, which triggered an immune reaction locally, sure. microglial cells, these spots were surrounded by the innate immune system T cells trying to control it. And what that ended up happening was that the brain's own immune cells, tried to shut this down, created inflammation, which ultimately led to the neuro inflammation seen on these MRIs.16:20 Yeah.16:21 So the fascinating thing about that is controlling the inflammation may have prevented these lesions from forming. That's not why these patients died. But it does give us insight as to why people will be having brain fog in the future.16:33 Without question, then guess what? That processes, even though it's specific right now about COVID-19? These things cycling out of control that that's not new, though, right? I mean, people have had these kind of problems before. And it's just like you said, it all goes down to inflammation. So what can we do to help control inflammation that doesn't get out of control?16:54 So what you just said, This isn't new? Yeah, you're exactly right. An article in 2013, in the Journal of neuro inflammation, shows that there are multiple lines of evidence to support the pathogenic role of neuro inflammation in psychiatric illness. why that's important is because neuro inflammation can lead and then they go on to describe all these psychiatric illnesses. Now, one of my friends had a recent zoom, 50th birthday parties, a football player and some other football players were on there. And so, you know, you start looking at all these, the players that played a career in that, and that's what I was thinking. I was like, you know, neuroinflammation, how do we protect all these? And then I started thinking about, you know, veterans and things like that. Looking at this article, we've known that inflammation does this for a very long time. So I'm like, well, recently, let's see what's happened. Let's see if they tied it to very specific diseases, do a Google Scholar shirts, and you will see that there's a link between neuro inflammation and depression, aggression, fatigue, obsessive compulsive disorder, addiction, anger, chronic pain, all of it. The the scientists return to today, he checks inflammatory markers in his athletes. Yeah, he trains a lot of MMA fighters, a lot of pro boxers and things,18:09 guess what he's checking, TNF alpha, interleukin six.18:14 So we already know from prior podcasts that eating functional foods will help with inflammation. So what I want to do is take a different turn. And like I was kind of prepping, let's prepare for the possibility that we may be dealing with more people that have neuro inflammation. So how do you handle it, there may be more mental illness coming towards us. Sure. And mental illness can be a spectrum, mental illness just might be a few. If you've ever suffered from anxiety, even a little bit of anxiety that that can incapacitate you. And that goes all the way to complete debilitating, OCD or schizophrenia and things. And it looks like it's all coming down to inflammation, let alone now we're just talking about the short term, let alone dementia, Parkinson's, and so on, which is, once again, inflammation is the cause of that.19:09 Yeah, absolutely. And I like that at the very beginning, you were at the very beginning. But about a minute and a half ago, you were talking about how do we protect these people like you saw on Jr's zoom call? But also, what do you do for those who are sustaining an assault right now or inflammation right now to heal them to help bring them back? Because I think it's both of those things. Let's say that someone's having an anxious problem, long term anxiety. Do you really think that having a long term poor diet along with that is going to help them with their mental state and recover it's not you still have to give your body the tools to give it I mean, a mechanic can only fix the car with the tools and you have to give your body the tools to help your brain heal.19:55 So when you have inflammation, there's a possibility that you are Maybe have a little more anger, which could lead to arguments. So now let's get into the physiology of arguing. I mean, I could see how heated you got when I was insulting Waterloo there. And I know. So this is a study that actually was published in in the Journal of nature and neuroscience. Basically what they did is they looked at people during an argument, right, and they tried to see what actually goes on. And so in a heated disagreement, generally speaking, you may lose respect for the person that you're talking to, you know, whether it's about something real heated or whatever, but if you're passionate about it, you will lose respect and whether you feel appreciated or not, a lot of times what is described as that the other person is ignoring them, or they feel ignored. And so there's a concept here where you're passionate about your thing, I'm passionate. When when I walk out of the room, I feel like I've been ignored, like you have not heard anything, and you feel the exact same way. And then there may be some truth to that. There could be Did you ever wonder what's going on in the other person's brain that could explain that? So understanding when you're looking at somebody, and you're like, I'm talking but you don't really seem like you're hearing me?21:12 Can I kind of guess on what you heard this may be going? Sure. So as a as a younger person engaging in an argument, I oftentimes would find myself, let's say that you and I were having a true disagreement. And that your your first approach to me was to tell me why you felt something that I was doing, or that I thought was completely wrong. So the first thing I hear is, he doesn't like what it is. And while you're talking and making that point, I'm really just fortifying my position. Really not even listening to anything that you would have said, however, as a, as an older adult, I would imagine, and you learn this as a parent to really go to the child or the person you have a disagreement with. And try to find an area where we already agree or even compliment the other person. So that you're really beginning to build a bridge and make it look like your point of disagreement is you're arriving at it that there's a problem that we have together.22:14 That is correct. From the top. Okay, now let's talk about what's actually going on in the brain that leads to that. Okay, so to get to that point, so that you can take control of it. So have you ever been in a heated argument? All right. So what they did is they took 21 pairs of volunteers, and they asked them to make financial decisions, decisions in particular, they each had to assess the value of real estate, then they had to bet money on there a second. All right, so each volunteer, terrible, I know, each volunteer laid in a brain imaging scanner while performing the tasks, so that the scientists could record and the volunteers had to agree on the price of real estate. If they agreed, each of them became more confident, and they bet more money on it. Which makes sense, because that's the tribalism if you affirm what I'm believing Well, yeah, we're both right. Are you kidding me? You need to buy some GameStop.Yeah, then we get really excited.23:27 I love this Reddit group.23:29 That's, that's exactly what it is. Yeah. So stop and think what Reddit is, when you do a sub group, you've already positioned yourself in a tribe. And when you say something, and you get up voted, you're just like affirming exactly what's going on. So that's totally cool. So I agree with you that I'm more sure that I must be right. Now what's going on is the activity is in the brain region called the posterior medial medial frontal cortex, which is also known to be involved in cognitive dissonance. And it's the part that will track the confidence level in the person that you're with. So there's a section of the brain that lit up when they agreed. And it was associated with the fact that they were agreeing and they had more continental cortex. No, no, no, it's not. It's the posterior medial frontal cortex. Okay, so wherever post posterior medial frontal Let me think about that. neuroanatomy is ridiculous. It's hard. It's like where is it? It's in the back. Middle. upper part. Yeah. On the lower. I mean, southwest corner. Yeah. All right. So anyways, so they found that the more competent one volunteer was, the more confident the partner became and vice versa. It and once again, it gives the feeling of why we joined tribes and why we seek out people with similar opinions. Okay. However, the interesting part is this when people disagreed, their brains became less sensitive to the strength of others opinions. Remember that the posterior medial frontal cortex when they agreed it tracked the content So I'm sensitive to exactly what you're saying. So what they're saying here, when people disagreed, they became less sensitive to the strength of others opinions. And after agreement, the post your medial frontal cortex cortex, could no longer track the partners competence on the scan when they disagreed and went, yeah, and went away. Consequently, the opinion of the disagreeing partner had little impact on people's conviction that they were correct. Regardless of whether the disagreeing partner was very sure in their assessment, or not at all, they doubled down. They went, Oh, no, they disagreed. So this one shut off, and perceived no lack of confidence in the other person. Does that make sense? Like it's, it's, it's not even a conscious thing going on very much sense. Blood went away from that part of the brain. And so pretty interesting. When they tested the volunteers memory, so a lot of times you'd say, Oh, they just didn't listen to me. They just didn't, they didn't remember it. clearly didn't remember. Because I feel that way a lot when you walk away, and you're like, well, they didn't listen, they won't remember anything. That's not the case. They actually tested the volunteers memory of their partners assessment and bets. Rather, it seemed that contradictory opinions were more likely to be considered categorically wrong. And therefore the strength of those opinions was unimportant. Yeah, that's right. So you can understand how we end up in this polarizing society, if that's going on. It's super complex, multi layered reasons for all this stuff. But how can we increase our chances, you said it best right there. So the end of this article was, well, if this is going on, do something First, find someplace to agree on first, because when you get to an agreement level, if you and I are agreeing, then I assess your confidence, and I automatically a part of my brain gets turned on. If we're finding the common ground, then I'm that part of my brain is ready to see if we can do this. So it's a subconscious thing. We don't know what's going on, it's going on on a physiological level, that that part of the brain kind of gets lit up. And so in the midst of a heated disagreement, just take a step back, find a common ground, and be like, Hey, I know that you're super passionate about Waterloo, and you're part of that subreddit, our Waterloo kill all other, you know, bubbly, but you know what, you know, what's really good? Doesn't matter the brand. I just like the effervescence, right?27:26 Yeah, it's all about the effervescence, as long as it's waterloo.27:31 So I'm the one that found the common ground, so I was prepared to accept your opinion. But you didn't, you didn't join me on that.27:38 The way it started 20 minutes ago.27:41 So the whole reason why I asked you the math question. So, um, it started out with Oh, my gosh, we're gonna have a lot of people with neuro inflammation. Oh, my gosh, they'll be arguing How do you prepare yourself for these arguments? How do you tell, like many things, I do better when I know, oh, I'm behaving like this. My body's doing this. I'm tachycardic. My blood pressure is rising, because I'm letting my emotions have a physiologic effect. Okay, so same thing. So you get an argument go, Oh, why am I being so dissonant here? It could be because blood is going to the wrong part of your brain, instead of where it should go. So that's step one. And then the reason why I asked you the math question, because this is the article that came out on January 14. disagreeing takes up a lot of brain real estate. This one is fun to me. Because much like the adage, it's easier to smile and frown. disagree, is exhausting mentally.28:36 I mean, think about it, you you have a great encounter with a friend, it feels good. And you don't want it to end if you're locked into a disagreement. Think of people sweat sometimes when they're when they're just having a verbal disagreement. And I've got Yeah, that's not even surprising. It's it's not surprising, but28:56 what is always surprising to me is when scientists can prove it, and they have tests to do it. Oh, for sure.29:02 Sure, your brains lit up on that one. So29:03 this one's really cool. So they is defense though, right? Well, we're gonna get into it right here. Check this out. It's more than just defense, something really unique. And it's fascinating. This comes out of Yale. So Yale, researchers devised a way to peer into the brains of two people simultaneously, while they are engaged in discussion. So when two people agree, their brains exhibit a calm synchronicity of activity focused on the sensory area of the brain. I'll say this, again, a calm synchronicity in the sensory area of the brain, okay. This was the sensory area. They didn't get into the exact place but it could be the amygdala, it could be you know, various areas. However, so many other regions of the brain are involved in higher cognitive groups. But when they disagree, so when you're agreeing, you synchronize in the area of the brain, that is the sensory area, okay? In other words, I can feel and see your social cues. Okay? So when we disagree, however, many other regions of the brain involved in higher cognitive function become mobilized as each individual combats the other's arguments. So say that again. So if we're arguing, instead of me just sinking into almost a Zen state of, we're in the sensory area right now, my brain knows that we're arguing. And so my brain shifts blood to the frontal cortex, where there should be higher cognitive functioning, and it's trying to prepare and figure out how we're going to do whatever and come back at it. And so it just, it just lit up and these people, so our entire brain is a social processing network. However, when you disagree, you lose the social processing cues, because you get away from the sensory aspect. I believe that so it becomes all trying to wrap your brain around the logical thing, why in the world, would you like Waterloo, and I'm, you know, so it becomes this, the state and you don't have any, any control over it. So to test their theory, they looked at 38 adults, and after they match them up, based on their responses that the researchers used, they put them in this really cool imaging technology called a functional near infrared spectroscopy. And what they were able to do is record their brain activity while they're engaged in face to face discussions. So remember, the last one, they were kind of in this functional MRI, and they were kind of arguing over a thing. This one specifically allowed them to do real time where two people could like, get in their face and be like, are you you know, like a argument or whatever it is. And what they found is pretty cool. 32:04 Yeah, so if I am.32:06 So if we agree, we are in sync? Sure. If we don't, then I'm trying to use my brain to figure out how to get you to do what I want you to do. So when they were in agreement, the brain activity was harmonious and tended to be concentrated on sensory areas of the brain, such as the visual system. thought this was super cool. Okay, think about when you used to date. And you could tell we're all of a sudden, it's like, the data is going well.32:33 Why is she walking away?32:39 So your date, your dating life? Was that bad that she actually showed up? You're like, oh, when she's leaving, or she's leaving to32:47 what am I doing?32:48 Well, you're, you're not in sync with the sensory areas. Yeah, learn that. But I thought this was fascinating. But the visual system as a sensory area gets in sync. And the visual system, presumably in response to the social cues from the partner.33:03 Okay. Makes sense, though. Because you're almost trying to complement what it is that the person there is doing. Right? That's Yeah,33:09 exactly. So like, I just think it's interesting. When you're like, man, I really, it's that classic thing. Oh, yeah, I know that person. Yeah, we had a great, really cool, we really connected or, you so easy to get along with or, you know, it's33:21 seen as kind of a bad thing, whenever, whenever it's highlighted, because a wrong decision ultimately is made. But there, I think it's just somewhat natural for people to long term when they are jiving with someone else to develop certain confirmation biases. And it's not necessarily always wrong. The conclusions, it's just highlighted when a confirmation bias turns out to be the wrong decision. Doe s that make sense? Because maybe when people are agreeing, and they're working together, it's actually fostering teamwork. And people need other people, wolves are in packs, etc. It's like part of that has to happen so that people feel comfortable working together. But if they're disagreeing, it's like you said, I'm your brains working this puzzle? How am I going to effectively remove myself from this guy's opinion or this thought? Because it's not working out for me. So you really don't care that the visual cue is telling you that the other person is uncomfortable. So you don't you're not tuning in to the fact that they're wanting to pull away? In fact, you're kind of glad.34:25 Yeah, that is totally true. The first article showed the activity, the blood flow, sure, this art or I'm sorry, that basically the blood flow, this article shows the actual activity and however they do it. So it makes sense that once we start disagreeing, I start shifting blood to the the cognitive region of my brain, and it just starts bouncing around trying to figure out how to do that if two people are34:47 agreeing, you're almost allowing yourself to trust the other person to help you in figuring it out. So you're a little bit more relaxed, it's not requiring as much as you begin to disagree. I just wonder if this plays into Little bit of biology like, Well, look, we're in disagreement, we're not working together, I've got to assume more responsibility of this thought this process this conversation.35:10 And then you know, these these guys looked at that, and they're like, well, meanwhile, if they're disagreeing activity, increasing the brain's frontal lobe, your home of higher order executive functions and filtering, and but that's a necessary evolutionary response. Yeah, because if I'm actually in a disagreement, like my like this could escalate, I need to start thinking and planning ahead. The problem is when you start having disagreements over stupid stuff, or things like that, or you have the same disagreement, let's say with a spouse, like you know, I don't know, it's really random, but like, clean up your bedroom, you're so messy, when you come home kind of thing, just random. And fortunately, since I disagree, I'm able to cognitively avoid that. You know what, never mind I realize I'm just going to go home and be in sync from now on and just be one with my mess. Sure, and just allow it to happen. Yeah, or I don't consider it a mess. Yeah, just said, I actually don't consider it that. So what knowing that we've got this synchronicity when this happens when two people agree that brains exhibit calm synchronicity, focused in the sensory areas of the brain, and discord, the brains engage in emotional and cognitive resources. Now, here's the cool part, if we're both disagreeing, and this is both going on, when we're in synchronicity, we're playing a symphony together. When we're disagreeing, and your cognitive functions doing this, and minds doing this, we're both playing symphonies in our heads, but they're different. Trying to play him at the same time. It's36:36 like a jazz band.36:40 So you're, you're equating jazz to cognitive dysfunction.36:44 drummers playing one song bass players playing another. I love jazz music, but it's wild.36:49 So the bottom line is, when you're actually in agreement, you have less cognitive engagement, you have more brain power to do other things. I thought about this, because when you're really like, well, like when we scope like, when I'm scoping, you get into this flow state. And things are good, just, it's just things just your brain just goes. And37:08 so over the years, we've worked together now several, I mean, really, I think the first time that we worked together as in 2012, and in that time, we've seen certain technicians in the room, right, come through and and work with you right now. And we, you've had several great technicians. But over the years, I've seen us where maybe you didn't have the one that caused them not that they were bad, but one that didn't compliment the way that you scope, or the pace that we have in the room, something like that. And right now, we're really fortunate because pretty much every technician that we have right now is really, really, really good. That being said, interesting, that when we're all on the same page, and we can have a we can have a day with several patients, but we catch every problem. patients feel great. They wake up awesome. turnover. Time is awesome. And we're all37:58 we're never behind. Oh, all those things still happen regardless, but we're just smiling more in those days. Yeah.38:05 Thanks for a great day other than I'm out of here.38:08 You know, what's funny about that? Now, that really brings up a good point where I have, I have a lot of surgical friends that do really kind of like neurosurgeons and things. Yeah, and wow, at what I would consider now where I'm like, man, they're so sad. They gotta have that same anesthesiologist, they gotta have those texts, they gotta have that certain music going. They gotta have that. That's not OCD. That's them getting in sync.38:28 Yeah. But it's, but it's kind of a home, right? Because everyone's agreeing with this environment. This scenario, and I do that same thing with Eckhart, when I'm doing is eyes, you know, I mean, it's, we've got a great pace. But some of that, honestly, it's kind of overused term, it's kind of curated, right, we have a playlist that we listen to, that the patients will relax to, but it's good for us.38:50 Yeah, that's gonna be a whole separate thing about the what happens when, you know, you played certain music, and they'd like now now knowing that you can, like examine the brain while they're doing you don't have to be hooked up to things. I don't know how this test was done. So I just thought it was kind of interesting thing, I went down a rabbit hole where I'm very nervous about the possibility of varying degrees of long haul or symptoms. I don't like the term long haul. Because we've seen this with other viruses. I see it all the time. I mean, we've seen it with EBV, we've seen it with,39:19 which is really new. And we don't have enough data, especially because you said it from the very beginning. They got people who've been exhibiting these symptoms for three to six months. And if you look at the timescale for how long this has been out, that could technically be for as long as they've had the problem.39:34 And then if you're one of these people, you're like, Hey, you know what I had COVID and nothing's happened. So I'm sure I'm clear. That's cool. be on the safe side. Do the thing that we I was talking about eat functional foods. Take in polyphenols, avoid fasting. Yeah, avoid fast food. And, you know, if you do find yourself in an argument, and you're like, Hey, you know what, this person probably has a lot of brain inflammation. find some common ground, get a box of Atrantil set it there and be like we both need to calm down. I need to improve my microbiome and you need to block that neuro inflammation that's making you so mean towards me.40:06 Yeah, they'll totally be receptive if that's the first thing. I'm sure.You look angry.40:14 You look angry. Have you had your ? That should be a commercial? We do. Yeah. Two spouses fighting. Somebody shows up.40:21 I mean, anyone loves being told that it's your significant other The first thing out of your mouth, how was your day? You look angry. Everyone responds to that.40:31 You look like you. Your frontal posters. cerebral anterior cortex is not firing. And40:37 yeah, just start off with a cotton that just anything nice shoestrings today?40:42 Well, thank you find that common ground.40:44 Yeah, start start with the shoestrings and then see if we can grow from there.40:48 Alright, so you can disagree. So So the moral of this podcast is that, number one, find yourself in an argument, first of all, give somebody the benefit of the doubt that, hey, they could be having some inflammation going on in their brain. And if you've heard this podcast and understand that, then you can stop and go, Okay, now I understand that blood is being shunted someplace else. So it's going to be very difficult to continue this path. Let's take a second, find some common ground and start there and see if you can work your way back.41:14 It makes sense. And it doesn't have to just be COVID. If you have someone that's in your life, and you're they struggle with anxiety issues, and you always wonder kind of why they're on edge, it may not really be their fault.41:25 Yeah, I mean, it all comes down to the inflammatory process that's going on. And if you've got neuroinflammation because of God because of other things, it's from a science standpoint, it's always real you can I think it's easier to see the other person's perspective when you can, when it's easier for me to always understand somebody's perspective, if I can break it down to a soul level, you're short of breath, that means that your co2 is you know, like, I can go Okay, that's cool. I'm not gonna say why are you short of breath? We only ran one lap.42:04 Yeah, it's this is what's going on. It's so weird to say to somebody. Yeah, well, I think it's a really good point. And I'll, I'm gonna pull the curtain back here a little bit. And it's not exactly just an anxiety, inflammation of the brain. situation, however, it is a brain situation. And it was somebody who was close to me that started acting a little strangely. And for a while no one really knew. But my dad, who was always happy go lucky. For a brief period in his life, there was 24 months or so where he was irritable. And nobody really knew why, however, me included, everybody, unfortunately, hadn't had an exchange with my dad. This is several years ago, where we would probably have like an argument where I'm never even heard just the guy growing up, really. And it turns out, he had a brain tumor. And once we got a treated, and he was back to us back to, you know, normal dad. But oddly enough, I'm just thinking of situations where you just have to have enough empathy that if you feel like someone's on edge, I love the way you said it, give them the benefit of the doubt, find common ground. If you've always been running into recall, someone just find the common ground, because who knows, you may actually help them. You'll certainly get further in your conversation. And I wished it. Did I known that even back then. I mean, of course, it we were we were over it quickly, when we all figured out what was what was going on. But it was something that he couldn't control at all. And but yeah, it's worth giving someone a bit of a doubt.43:44 The brain is so fascinating to me, because when you say that he couldn't control it all whether it's a tumor or whether when people I was listening out, man, that fighter that's on Joe Rogan's most recent episode. Oh, what's his name is? Justin Ren. Justin read.44:01 Yeah. Is it just an idea? He does the in Uganda? Yeah.44:06 He does such an incredible job of explaining addiction and depression. He's been through it in a way that you're just like, Whoa, yeah, like I did not know it got like that. And even Joe was like that. I'm just the kind of guy that can walk away from things. And guess what, some people could have walked away from everything that he struggles to walk away from. It's just not how it worked for him. And it's how his brain is wired. And it helped him to understand he actually said that flat out he's like, once it was explained to me that I have less dopamine going on. And once I take this, it hits me different than it hits other people. And finally learning that allowed me to realize this is not a mind over willpower kind of thing. This is strictly when I do this. This is what's going to happen. If you're a diabetic. And I'm like, Eric, I got the greatest donut. You're gonna love it. It's amazing. And you look at that and go well, if I eat that my blood sugar will spike and I will end up Possibly, you know, an hyperglycaemic crisis. It's that makes sense, right? Yeah. But we never talked about the brain, we never say, oh, if you drink the day before, maybe the following day, you may end up with your GABA receptors depleted, and therefore you'll have increased anxiety. And that can lead to panic attacks. Yeah, things like that.45:19 My cousin, psychiatrist and years and decades ago, I remember him telling me that one of the most difficult things to deal with in psychiatry is that it's not like orthopedics, you can see a broken bone and want to fix it. You just can't see the brain, you just see the resulting things of people's behavior. And that's kind of hard, because it's all when you're little, you're told to behave, Oh, of course, behave, do the right thing. Whatever. If someone misbehaves so many times, it's attributed Well, they've chosen to act poorly. But maybe, maybe some things are just in a process of inflammation where they're making. Yeah, they're making bad decisions, but maybe they're arriving at the decision, not really, how they wanted to get there. And then, you know, we46:07 talked about what we've, I mean, CTE is a relatively new thing. But CTE is now showing up. And not just in football, it was discovered there. But now we're seeing in MMA fighters, which we thought MMA was safer than boxing, because, you know, you didn't get hit 20 times. But now we're seeing some of these fighters do some different things we talk about some of the very, you know, some very sad and horrific suicides, and some things like that have gone on with people that have had long careers in professional wrestling is one and that and you're just like, Whoa, and people want to block your players.46:39 Oh, really? Yeah. head butting? Oh, yeah, knocking that46:43 knocking the ball around. It's great. It's crazy. And so it all comes down to inflammation. And so it's it's sort of, it's sort of my life's mission, you know, the brain gut access, decrease the inflammatory process in the gut, and the brain and the same thing, and we can do it all the time. You know, increase your NRF two pathway, decrease your your TNF alpha, your interleukin sector and liquid ones. And those are those are fancy words for just saying, Let's stop the inflammatory process.47:09 Yeah, that's it. It's crazy. But it's all it's not it's all but so much of disease and chronic disease is just tied back to inescapable long term inflammation.47:20 And that's so good. Circling all the way back to the very first thing that I said the whole Wim Hof thing as I started reading about it, actually one of my patients who's suffering a lot from a multitude of symptoms, kind of like a systemic inflammatory process. And it's really kind of struggling to come out of it. And we've tried a lot of different things. He's like, he's like, Doc, it's like, I've been doing this thing called Wim Hof Method now for a couple months. And I was like, I'll try anything. And then as I started looking at it, it actually, because you control the parasympathetic system, which is the vagus nerve, which is the great highway from the gut to the brain, you actually do change the whole, well, I don't know the exact aspect. But if you're affecting the parasympathetic nervous system, you're going to decrease neuronal activity in areas that you don't want it to be hyperactive. So breathing, that's how come calming breathing increases parasympathetic, exhaling, and that's how come there's so much meditative yoga. And there's so many things like that there's a physiologic thing that goes on if you do it, right. Which also brings up an interesting point, because I just thought of this, just now, every time I've ever done yoga, like a yoga class, and I've done quite a bit, it's mainly just to kind of get it out of the way. It's like, I'm gonna go do my stretching thing. And when they say home, and they do this, and I had cognitive dissonance, I was like, I was gonna argue the fact we don't really need to make these weird sounds, can we just stretch? And now I just realized, and here I am, I did that. I went in there with a disagreeing attitude of why we have to do these other things I just wanted to get my stretch on. And I'm at fault for that. I just realized, I just noticed that there it is,49:03 you know, even when someone's intubated in surgery, in your right eye when you're applying the yoga and the humming or whatever, because basically, you're creating resistance for the air to leave the lungs, etc. The hyperinflation of the lungs. Well, guess what we do someone's intubated and we need a valsalva maneuver, we basically just hyper inflate the lungs, but we're just doing it mechanically. And it's because it's been proven time and time again that that is going to stimulate the vagus nerve and get the acetylcholine from the Vagus,49:34 man. See, this is what I liked that book so much. They went into that where they said that if you slow exhale while humming through your nose, you actually increase nitric49:44 oxide in the blood as well. Yeah, because you need the veza dilation to bring in blood that's been metabolized or the blood it's been bringing the metabolites co2 back to the lungs be breathed off. I mean, it just goes in that cycle over and over again. And it's kind of cool because this is This is really why I want to do this show, I think because later after you do some more Wim Hof, because I'm really curious on how they explain it to the layperson. Maybe we could lay down a little bit of physiology that way that if someone's sitting there, sitting on the edge of Wim Hof, or nesters ideas, we can actually show physiologically why what they're saying,50:20 actually makes a lot of sense. And there's a lot of science on this. I think that a lot of academic institutions have used him as a guinea pig because he allows it because he's not only a believer, he is the example he Yes, and then they can show all these different physiologic changes, but it's really cool. So like, I'm thinking, you know, practice, practice what we preach here. I don't know like next time I find myself in an argument with somebody have something locked and loaded, that you can agree on just so that you can almost like press the reset button. Possibly. Yeah. Oh, wait, hold on. I know that you're doing this. But if you're noticed, and then just something that's kind of that everybody will agree on me. Of course, everybody likes Jolly Ranchers. Yeah. You know, that's high fructose corn syrup. Yeah. I was just thinking of things that people would normally like. Yeah, normally.51:11 Yeah. Honestly, in today's climate, I don't know that there's any one thing other than you could say oxygen is good to breathe. And Sun is good most of the time.51:20 I know that the Lord is gonna call you up be like Eric, what happened? Every time that I want to tell him to go clean his room or something? He says that that don't you think that my hair looks pretty? It's it's become a weird tick. I51:35 think we need to scan as bright as the common51:39 that's common ground.51:40 Yeah. Well, man, awesome. Awesome. Surprise there. I love I love the topic.51:47 But we're good. We're gonna get sciency Yeah, we're gonna have some guests on that can can kick some knowledge on their books and on the on the research that they're doing?51:53 Yeah, keep an eye out for Olivia and Aiden to be joining the podcast here really, really soon. Sweet. I'm excited about that. And we're still not finished with the installments on on the immune system, literally. Keeping up with the email over the last episodes, as well as preparing for a couple of other things. Just the new year is etc. We've had a really bizarre shake up in our schedule at the info center. Whether we're full or not full of random times. There's news. Yeah, life still goes on here too. Hey, we52:26 got a new president of the United States.52:30 Oh, yeah, that's right. I forgot about that.52:32 So there was immediately executive orders, which were like, Oh my gosh, how's this gonna affect us? And52:36 did you know what we have to work? We still have to put gas in the car. So take care of the kids. Ultimately, all politics is still local. I still gotta be nice to everybody around the house. You know, you said52:48 you put in order gas in the car then kids and I know deep down USA stuff to work got to buy my Waterloo. Oh, Bill, the gas52:57 that's given. It's like taxes,52:59 Episode 48. So next time, if number one, hopefully you will never get COVID if you do get COVID and it's mild. Keep an eye out that there appears to be a low level inflammatory response which could lead to other things so control the inflammation by controlling your diet eating a very colorful plate. Top zinc Yeah, takes a vitamin D. The polyphenols in our trunk to have been shown to help with the innate immune system. See Episode 47 your sleep? Absolutely. pillars. So any parting words hurt53:30 now? Thank you all for for I mean, seriously, the the last two episodes the amount of email sharing. Thank you. Yeah, and I appreciate it.53:40 Yeah. So please, like subscribe, the usual stuff, share it. We want to try and get the word out and if there's any questions or anything, email them, we try to get to it. We have Angie Coker secret weapon who will find any article anywhere in the world at any hour.53:57 Yeah, he gets some sleep.54:01 All right. Thanks, everybody. Bye bye. It's54:02 Episode 48 till later

The Actual HOW to Boost Your Immune System

Play Episode Listen Later Jan 12, 2021 54:30

0:00 Hello, everyone, welcome to the gut check project gut check project fans, KBMD health family, how are you doing? It is now time for episode number 47. I'm here with my awesome co host, Dr. Kenneth Brown. 0:13 What's up Episode 47. This is part two of our immunology. So this is I'm pretty excited. Because just this morning, you said you better check out Joe Rogan this morning because Dr. Mark Gordon is on there. And this dude was saying everything that we've been talking about, but I feel like we even have it to the next level. So we're talking to scientists that understand the whole concept of functional nutrition, functional things that I felt like he was saying, everything that we've been talking about now for quite a while like yours0:45 is no doubt the coolest thing is another thing that we'll we'll get to it in a moment. But it's it's all about eating right. having great nutrition, he used an incredible example of India, where Let's face it, a lot of people don't have the economic means that we do here in the United States. However, they're facing COVID, they have the same health issues that we do here, roughly, and they've got a large population. So when comparing apples to apples are talking about nutrition, and there's some specific things in that nutrition when you say,1:17 oh, and we're gonna get into that, in fact, I got an article here that we're gonna go over and I'll spoiler alert for you. But it's exactly what what what we're talking about right now. So we got some feedback. I apologize to everyone the last podcast we did, we were trying some unique things. And we didn't have such good sound quality, but that's what you get when your sponsor is lousy Lavalier comm so we had LousyLavalier.com Yeah, so we dropped them. And so I'm happy to announce that we got a new sponsor, which we did get a new sponsor, and this is awesome. It's actually a hot dog company. They're called diarrhea dogs. And their slogan is, we're not sure what's in the dog, but we know it will give you diarrhea. Yeah. who's who's betting our sponsor?2:05 The cool thing is, is it's a it's a host specific sponsor, so I'm looking for you to tell me how I2:11 know seriously, who in the company is? Is it Mike? is Mike getting sponsors for us, Mike, because I've already cashed a check. We got to keep talking about diarrhea dogs.2:18 It's, I can't this can't keep happening.2:20 We had lousy Lavalier as a sponsor, then we followed up with diarrhea dogs, yeah. Oh, my goodness,2:25 this is not working out.2:26 We're gonna have a little talk with Barry Weiss. How you been man?2:30 doing well, so we're into a brand new year now. What brief amount of time had a great vacation with the family? And it really just in time, right. I mean, there's, everything's kind of limited on what you can do. Yeah. But we it was, it's good to always have the older son come home spend time with him. We started building some furniture over the last couple weeks. So it's a great bonding experience with me and the boys. And of course, Maria is telling us what she wants us to look like. So trying hard to make it. Yeah. But you know, it's it's been a lot of fun. Mac is in the swing of basketball. And so life, normal life is starting to take on a new meaning. But it's it's good.3:09 Yeah. What about you? Well, for us, um, you know, the, the whole COVID lockdown, you start looking at your house a little bit. And so loida kind of convinced me that maybe we should start considering making a few little changes. And it started out with the master bath. And she's like, you know, shoot, can I do a few other things? I'm like, Yeah, absolutely. So I'm really busy with work and come back. And then you know, next thing I know, the builders or the contractors there and he's like, Look, okay, so this is what we've designed. Here's the plans, bla bla bla bla bla, and, you know, he's like, we're gonna buy the neighbor's house and we're gonna, you know, tear, tear this one down. But I mean, it was just I'm like, Whoa, we're doing a lot of work here. So I'm already in it. We're gonna be in this house for a long time. It's a great area. You notice everybody's moving to Texas. They definitely dragons bringing everybody down here. So following him. So at3:54 any point, did you have a spreadsheet that said, redo house or simply burn house?4:01 Well, then it's like one of those shows. Like once you see the plans, you're like, Oh, yeah, I want it to look like that. But you know, and oh, guess what I did today was that guess what I did? 30 seconds ago. Oh,4:12 I know what you did? Yeah, you got into crypto.4:15 So as we're setting up to do this show, we started having a conversation about cryptocurrency and Bitcoin and people have been telling me to get involved. So in a spur of the moment, while Eric was setting up the mics and everything I bought some Bitcoin Yeah, go Bitcoin.4:29 Yeah. And and we need to probably have a disclaimer that we know nothing about cryptocurrency. Oh, absolutely. Nothing nice. But yeah, it was really kind of cool to watch you do it.4:36 Yeah. So we've covered our sponsors. A little word with the person that's choosing them in the future. And so let's jump into the immune episode part two. So even if the audio is a little bit off on that last one, I encourage everyone to look at our last podcast, because I do a detailed explanation in or at least detailed for a simple country butt Dr. That's living in Texas for the innate immune system, and I actually rewatched it when we were getting the comments great information, audio bad. And at the very end, I go, so that covers the adaptive immune system. I'm like, No, I should have no it was the innate, we did not cover the adaptive yet. There's a reason why that's coming, because then we're going to lead into the vaccinations for COVID and things. Right. So that was the innate. But here's what's really cool. We're gonna talk about what Dr. Mark Gordon was talking about on Joe show. And it's super cool. Like we've been on top of this the whole time. It's been it's it's actually huge, huge news for everyone.5:36 I think a lot of people can learn a lot about what they can do just to protect themselves. And let's small preface, you don't have to just apply the knowledge that you'll pick up today to COVID. COVID actually can begin to fit into other viruses with this talk that we're going to have today.5:52 Yes. And specifically, this is not a COVID talk. We're not saying that at all. What we're saying is we're gonna talk about how to optimize a well running immune system. Yeah. And so when I talked to some of my colleagues and people discuss different things, Angie, and I were talking that she's like, have you looked at our Mendeley account? So Mendeley is where we put all our articles, and I just did a quick look. We have over 1000 articles regarding immune health and how to optimize it through nutrition and lifestyle. Yeah. So even that is science backed. Everything we're talking about here is completely science backed. In fact, one of the things I wanted to discuss because I think it's really cool is this article that just came out in 2020. It's called the antiviral functional foods and exercise, lifestyle prevention of Coronavirus. That's a very boring title. And those are the kinds of things that I read. And it was published in the Journal of nutrients. What's fascinating about this is that they discuss the things that other people are now just finally starting to talk about. Yeah, so I want to review this article really quick. Then I want to get back to the whiteboard. And hopefully sound a little bit better.7:06 We're gonna use headphones today.7:07 Yeah, we're gonna try and use headphones. I got a new mic attached to a hemorrhoid bander because I feel very comfortable holding hemorrhoid banders. Yeah, so that is dry tone right there. That is right there. 7:20 that's almost as good as the Bob Barker microphone from the remember the little skinny one that he had on7:28 the show? Yeah, when they tell you to go spay and neuter your dog.7:31 Yeah. spay and neuter your dog spin the wheel. Drive. I can't wait. I had a hard time of that. Anyway. Yeah. Yeah. Great show.7:37 So basically, on this article, it's really interesting. Not actually not interesting. For us. It was it just reiterated everything that we've kind of base talking about. What they looked into was functional foods. They called it functional foods, and physical exercise. So the exercise part was a brief part than 90% of the article was talking about functional foods, which they described as functional foods being polyphenols.8:02 Incredible.8:02 So the functional foods are polyphenols because of the various mechanisms that they do in the body. We got contacted by an author of the sirt diet. That's sirtuins. And he noticed that we've been talking about polyphenols and said, Wow, you guys are on that. So the whole thing about Adele's diet that she lost all that weight, that's called the sirtuin diet or the sirt diet. And then I've watched it on Dr. Oz. And I was like, there's something about polyphenols, polyphenols. And the reason why is you're gonna see on this whiteboard, how many different ways a functional food like a poly phenol can benefit you definitely. And so the cert diet just means that you turn on certain genes, it's an epigenetic thing. So really quick on the exercise. No big surprise, as it turns out, exercise is pretty good for you. Sure. So they looked at different aspects of it. And what it does do is it does activate natural killer cells, and will induce monocytes to become antigen presenting cells like dendritic cells. If you go I don't know what that is. We talked about that on the last episode. And we're going to get to it again here. So don't worry. That being said, super extreme exercise, which we have talked about this can actually lower your immune system. So many times when people train super hard, and we're talking about like, marathons and triathlons and marathon running. I've had so many patients that get very sick after they really train for something, they go all out, and then they get sick. And it's because I didn't even realize this, that you produce so many reactive oxygen species. This damages cells, which leads to inflammation, you're gonna hear this term over and over again. And then it actually adversely affects your white blood cells ability to fight off infections. Yeah. So the real idea is that regular exercise is really good for you. It gets rid of old immune cells that don't work very well. And you actually stimulate young healthy cells that can actually have a young, healthier immune system. It has been shown that highly conditioned athletes have a much better functioning innate immune system, as opposed to sedentary people. Yeah. So when we're sitting in a viral season, and if you're sedentary and you're overweight, and you got diabetes and high blood pressure, your immune system doesn't work as well. And there's reasons for this in this paper. So then they kind of went through that they're like, yeah, okay, so exercise is good. And then they go into 90% of the rest of the article is discussing polyphenols and the multiple areas that these functional foods benefit our immune system. Okay. And, oh, we're probably jumping ahead. What's a polyphenol?10:40 Oh, what is it polyphenol? Yeah, tell everybody what a polyphenol islittle compounds that are found. And fruits and vegetables. Generally they are what can be responsible for the coloration that's inside those fruits and vegetables. And they they're naturally occurring. Some of them are large, or small. But in essence, our bodies love them.10:59 Absolutely. So I always refer to them as mother nature's secret weapon. This particular article goes into great detail about how the flavonoids, terpenoids alkaloids in the polyphenols, so they can go into that are actually bio active, they can influence genes have peptide qualities, and are broken down by our microbiome into potent anti aging, anti inflammatory, anti cancer metabolites.11:25 Right. You know, I was thinking about this, how do we bring validation to this part of this study, or the I'm sorry, the discussion, I guess, whenever we're talking about this to people, because I started thinking about, if someone years ago when you were when you were young, and someone said, you probably need more calcium to make your bones strong, you didn't just go to the store and buy sack of calcium, you generally just started drinking more milk or something similar. Or if you were an athlete, and you knew that you needed to make sure that you didn't get cramps, you ate bananas, or ate spinach, all of that stuff, you didn't go and just buy the little element, those elements are naturally occurring in something that you're eating or drinking. That's essentially what we're trying to talk about with polyphenols is there are small little things in there that your body craves, just like your bones want calcium, the these are the vehicles, these are the foods that will deliver what your body wants to maintain health and keep you healthy 100%. And they mentioned how versatile polyphenols are.12:24 Oh yeah, meaning they function in many different ways. Number one, they can have potential influence on your gut barrier, where they improve the immune system of the gut barrier, the first portion of that, then they actually have epigenetic phenomenon. Most important is that your microbiome will break these things down to beneficial products. And that's going to be something that we've talked about post biotics before, I'm very excited. We've contacted this a PhD in Argentina, who has one of the most amazing articles describing the post biotic effect. And they actually demonstrate that the larger, more complex polyphenol is the best way to consume it. In other words, yeah, you don't want to take the one little molecule. So that's pretty much what they said about polyphenols, because we're gonna talk a lot more about that. And then it kind of like briefly go over Oh, and then there's vitamin D, which is pretty good for y'all. So vitamin D deserves its own show, because it's more like a hormone than it is like a vitamin here. And then they look at a couple other things like vitamin C and stuff, and they kind of gloss over it. And then they come back to the polyphenols. And they're like, and then they reference to the viruses. And they show how there's so much information out there about how these polyphenols actually influence the destruction of multiple viruses like influenza, Zika, virus, HSV, and Corona.13:45 And there's a mechanism to and there's13:47 a mechanism for each one of these. So the conclusion is, and this is, I hate to say Joe Rogan, for the third time in about first five minutes, it'll validate what we say. He's always said, why aren't we discussing ways to improve our immune system, prevent ourselves and do this, these guys end the whole article, and by the way, it's thick 20, some pages with references and everything they end it with the conclusion is, this is a pretty cheap and simple way to improve your immune system or optimize, get some exercise, eat some polyphenols and get a little sun. Yeah, that was the combination of it. All right. And and these people put a lot of work into that. And that that's a spoiler alert.14:31 I think I might have said though it's really, really important is that there's a lot of work. There's a lot of research, there's a lot to take in here. However the solution if you really think about it, it isn't that difficult to adhere to this to keep to keep people healthy. That's actually the coolest part. The summary of it all is polyphenol, sleep exercise. You're off to an incredible start just with that and don't i don't think you should shy away from Rogan at all. He supports tons of other podcasts gives huge mentions to other people. They're doing the same thing. When I heard Dr. Mark on this morning with him, I just I liked it because it not only was somebody else talking about the same subject, but he was doing it in such detail that we like to talk about it, that I encourage you, we're not the only ones who have this level of research and are seeing these kinds of results with people.15:22 Oh, it's so cool. And now because we're in these circles with these PhDs, I'm getting preliminary data on different studies where it's humans, where they're looking at what I'm going to talk about here. Yeah. So what I thought we could do is try and do round two, you put some headphones on, 15:37 I'm going to have to,15:38 I'm going to grab my Bob Barker mic right here. I'm going to turn this one15:46 that was kind of quiet. And now I'm going to come back like this. There he is. This is why we have headphones. This is15:52 why we have headphones. And now I'm going to switch the cameraprobably should have you looked at the computer to make sure that I'm in focus and everything. And now, let's do a recap of the last. And that's not a window of the last podcast that we did. This is a kind of quicker version of what we did. And this is to get everybody up to speed because when we talk about polyphenols, we need to make sure that you understand exactly what's going on and why there are functional food. So just to recap, the innate immune system is your response to any type of damage, whether that damage is through physical damage, whether that damage is through infection, whether that damage is through repeated poor diet choices, your body is going to try and repair itself. So let's walk through what happens. The first step, step one, let's just assume that you have an infection. If you have a virus or bacteria, what it will do is it will attack a cell. So that cell no matter what it is, sounds an alarm. And it notifies its neighbor, which is kind of its bodyguard, the mast cell. The mast cell then releases what is called braided cinan. This is really neat, because if you ever sprained an ankle or done anything, this is what's going on. The braided cinan send different proteins or cytokines to the blood vessel. First step is the blood vessel. And what it does is it actually normally the blood vessels have very tight seals, what it does is the blood vessels pull apart a little bit to allow fluid to come out. Well, the reason for that is is that you want the swelling to contain whatever's going on. You sprained an ankle, you go oh my gosh, look at my ankle, it's so swollen, well, it's there for a reason, because that fluid is trying to concentrate what your body needs in the same area. So the fluid starts coming out step to these braded cinan, and different other cytokines send up little flags, just like Velcro sticks. And these are called intercellular adhesion molecules. And what they do is they grab white blood cells that are swimming by so these white blood cells have these little hooks and they get hit and they stop and they go, Oh, what's going on all the fluids going out that way, I'm gonna go out that way. So then the white blood cells join this little party over here. This is what ends up causing redness, swelling and pain anytime you have any type of infection, anytime you have any type of injury. So now we have these white blood cells, what they do is they go, Oh, that mast cell told us to go that way. And so the white blood cells head over to what's going on. And then this allows your body to fight the intruder that's doing this. So that's step one. So now these white blood cells come around. You heard me say in that other study the antigen presenting cells. So one of these types of cells, which is a phagocyte, will actually first thing it does is it swallows the invader, bacteria, virus, fungus, whatever it is, swallows it, and the reason why does it it digests it, and then it breaks it apart and goes, Okay, this is what it looks like. So it puts wanted posters on its outside. So this guy said, I know what's attacking us now, this, this guy right here. So these antigen presenting cells, put it on the outside, and then they do something else. They release cytokines, specifically, multiple cytokines, but the important ones are TNF alpha, interleukin six, interleukin one, interleukin eight, and you're going to hear a lot more about this, because I'm talking to scientists all over the world. And people are now studying specifically how we can use functional foods to control this response. So TNF alpha, does a lot of things. It's a pro inflammatory cytokine. And so we know that TNF alpha is used in very expensive drugs block that for rheumatory arthritis for Crohn's disease for ulcerative colitis for all of that. So TNF alpha does something kind of interesting that I found unique is it actually goes to the hypothalamus and it increases your core body temperature. So when I say these are bad, they're really good for you in small amounts, it's when it becomes too much that it becomes bad. So TNF alpha hits the hypothalamus increases, and that's how you get fever, interleukin six, it goes to the bone marrow and increases the white blood cells. So this is why you have that achy feeling if you've ever had the flu, or if you're gonna get a vaccine, and you go, Oh, my gosh, I had a vaccine, that kind of hurt, I feel like I have a low level flu. It's because the bone marrow is producing more white blood cells. interleukin one goes to the liver to produce acute inflammatory reactance, which goes into something called the complement system. But that inflammation is what we measure in people. In fact, cardiologists use this all the time they look at C reactive protein, yeah, because when you have inflammation, the liver produces this. So people with coronary disease will have increased levels of that, and then interleukin eight.Fascinating, it basically produces more of those little Velcro hands. So then we come all the way back to the blood vessel. And now we've got dilation, fluid coming out. And every white blood cell that's coming through gets grabbed. So when you have the white blood cells producing here, you've got the fever, which increases the amount of blood flow heart rate is faster, everything. It's an phenomenal and just beautiful little system. Yeah, it is. And when it works great. It's exactly what we need. It's exactly what you need. In the acute phase. Definitely the innate immune system is here to protect you in the first phase. So now step three of the innate immune system out of you, but that's the antigen presenting cell, the one that we were talking about over here, sometimes they sometimes they get overwhelmed, and the virus actually wins. So the poor little guy dies. It's that's a good cartoon. Yeah, so the poor guy dies here. So the antigen presenting cell dies. So it leaves rubble, so it's comes out and the body even gets that. So reactive oxygen species are left behind, that's known as oxidative stress. That's good in small amounts, because that will kill other things around it. Assuming that this guy got overwhelmed when he dies. Maybe other cells are being overwhelmed, and then that oxidative stress will kill it. Yep. This is known as a reactive oxygen species or reactive nitrogen species. But when that goes on for a long time, that's what actually causes chronic disease, like heart disease, cancer, aging, this is actually why we age, reactive oxygen species, autoimmune disease, dementia and obesity. Nobody ever thought that you can become fat because you have low level chronic inflammation. And I've talked about this on other episodes. 22:56 Definitely.22:57 So final step here is the thing you didn't know about, which is the toll like receptors, right? Okay, so toll like receptors is just another layer of defense, where if these toll like receptors are actually activated, they do very specific things. For instance, the toll like receptor number seven, is very specific to release certain things to fight RNA viruses. You can go through these others, there are ones that are built to fight bacteria that are flageolets flageolets. Yeah, I think we're both saying that wrong, but that's okay. fragilities, flageilities. And they also do something that we have talked about before, I want to say we talked about it. On at least three episodes, I can think of the epigenetic phenomenon of nuclear factor Kappa beta NFKB. So when the toll like receptors turned on NFKB goes up. And NFKB is the one that we talked about with the broccoli episode, right? with David Roberts and john gilday. On Yeah, this is the one that actually has a what's called plio trophic phenomenon. So it affects many different things. So when NF Kappa beta is turned on, then you go through a huge surge of our old friends, TNF alpha, interleukin six, right? So he has more inflammation with inflammation, the common theme of inflammation, right? So inflammation, what does inflammation lead to? Oh, this dementia, autoimmune aging, cancer, heart attack na, so this innate immune system is here. The other thing that I did not mention was that when the toll like receptors get turned on, like this toll like receptor number seven, which is for viruses, one of the things that releases is interferons. interferons, actually, are molecules that directly destroy cells that have been infected with viruses. So if you were to get a virus, you breathe it in through your nose, let's say it goes to your lungs, a cell is being attacked, it can actually send a signal to a healthy cell says We're under attack, you need to be ready for this. And that's the little cell that waits with a gun at the door. So when the virus rings, the doorbell goes and shoots it. That's not proper technique and how you shoot it. We've25:21 seen actual footage of this going down at a microscopic level. So yeah,25:24 it's it's fascinating. Yeah, absolutely. It's like watching an old Western, just like oh, my gosh, and the. And it's totally true. Because the viruses that show up, they always wear black hats every time every time. Yeah. So that's a recap of very quick recap of what we talked about last episode. Yeah, I get it a little bit more detail. How's it? How's the sound quality?25:47 The sound is much better than last time.25:49 Okay, good. So hopefully, we'll continue with this. So how do we describe how functional foods work? Because our big thing last time was improve your immune system do this, but nobody talks about how, why?26:05 I've got a question for you. So when we look at this, and I think this is a reasonable question, you look at it, and we're talking about all the bad manifestations that happen. When there's too much TNF alpha, or aisle six or aisle one, we have too much row s, or I'm sorry, reactive oxygenation, species, ultimately, too much inflammation. But I needed all of this to happen. So, Dr. Brown, what is it that I'm missing? That would help me not have the system that I need? That keeps me alive and safe, run out of control? And basically, ultimately destroy me anyhow?26:42 Absolutely. So what we're talking about is how do you optimize? Yeah, well, running immune system. Definitely. One of the theories right now is that why do younger people not get sick with the current virus that's going around, is because they have a very good innate immune system. As we age, as I mentioned, as we age or you become sedentary, possibly, this happens. And so you go, Oh, well, I still don't get that. We'll imagine this. Imagine quietly, this attack happens, virus, bacteria, anything, and your innate immune system is kind of slow to react. And by the time it realizes, Oh, my gosh, something's going on. Many cells have been infected. Which means when these cytokines go up, it's a huge amount. If you have a really healthy innate immune system, you catch it at the first cell. Yep. So let's talk about functional foods. functional foods, functional foods, polyphenols, so I'm going to use these little brand. These little hexagons. Yeah. Demonstrate functional six added. Yes. Excited. Whatever you go.27:50 All right. Now hexagon, you're27:52 right. This is all based off of science. All based off of very detailed documented, I want to thank every PhD out there who goes through this kind of trouble and probably gets no recognition. Because this is Sony. And, you know, we're talking about so when Dr. Mark Gordon was on his show today, he didn't really understand why course it's an or why tumeric does this. Let's talk about that. Let's do that. All right, step one. So this will represent the different stages that it actually happens. Step one, intestinal gut health, intestinal gut health, that's your first barrier. Anything that comes in, you're going to make sure that you have a good healthy working gut, healthy work in gut. Step two. We know that it has potent antiviral activity. I mentioned earlier in the other article about how these functional foods can actually destroy viruses on contact.28:52 So we've got gut and the virus itself.28:54 antivirus itself step. If the virus makes it past that, inside the cell itself, is the M protease that allows the virus but bacteria do this also. It has to attach to the cell. Well, what does it do? It prevents it from attaching then, oh my gosh, this is a really tough virus and it made it through all these lines of defense already. Yeah. Well, as it turns out, bunch of foods polyphenols actually work zinc Ionafores and prevent the replication29:35 Hmm. Blocking replicase 29:37 replicase correct. Nice actually blocks the replication.29:42 So So right now we have four tags up and we're still on number one of the innate immune system. That's29:47 why it's so important to understand the innate immune system. Yes. And why nobody's talking about this. I'm going to keep going. Yeah, and this is not once again, this is not my opinion. Yeah. We've got 1000 articles to To show all of it, right? Okay, so now we got our friend, the mast cell over here and everything that I'm saying is not an on or off switch, it's the optimized way to do it. If your body needs it, these functional foods help it ramp it up. If it doesn't, it does it. Alright, so the mast cell that releases the braided cinans that go to the blood vessel, oh, the mast cell actually gets stabilized by functional foods, polyphenols, nice. So it doesn't overreact or under react, then it's almost like, really, truly Mother Nature's secret weapon, then the blood vessels which release the fluids, there's something called or I forgot what the actual enzyme is, but it actually attenuates the enzyme that creates the leakage. So it controls the amount of fluid that comes out. And in the same line, what it does is it actually controls the amount of the adhesion molecules, so all those little hooks that grab that, right, it actually does the optimum amount for that. Okay. So getting back, this is why Dr. Mark Gordon was like, Oh, we have shown that it helps with inflammation, I'm going to tell you exactly where it helps, right whole pathway. Okay, so we've now blocked the little adhesion molecules so that only the right amount of cells come out, only the right amount of cells come out. And remember, when I said that it monocytes become our antigen presenting cells, it helps them mature. Oh, it's like steroids for those guys.31:35 So it activates them. It's a growth hormone, right? So we're allowing these phagocytes to now do their role. And by having the right amount of polyphenols available, it's going to do it quicker.31:45 Exactly. So we're now heading to step two. So what does it do? Oh, yeah. It helps the antigen presenting cells, taking the vacuoles and put those different proteins on the outside quicker, because it's already made these more mature. And then we get to the real important part, it tells the antigen presenting cell, yo, be a little careful how many cytokines you send out. Hmm. So there's multiple studies looking at each one of these. And so I'll do this real quick. While you're32:19 putting those up there, I'll just add that Dr. Gordon spoke today specifically about how high circulating cytokines lead to insomnia and an inability to rest enough because it causes neural inflammation, which is just building on it. That's32:33 right. He did, he talked to specifically about that. And that's that brain gut connection and percent inflammation, that's what we always talk about. So as it turns out, it tells the antigen presenting cell, Hey, be careful what you do, then just to make sure as another safeguard, it specifically will control how much TNF alpha, how much interleukin six, how much interleukin one and how much interleukin eight is actually necessary. And these are all documented on specific studies. And I know that these are being done in humans right now, because I'm getting preliminary results. And they're showing very specific in vivo, meaning people that have this kind of situation, actually decrease these different cytokines. So it's not just a total decrease. It's the right amount. So if you need more white blood cells, then there's no reason to shut it off completely. Right. Like we just can't You can't be smarter than Mother Nature. Yeah, comes down to Okay, how am I sounding sound good. All right. Now, let's go to it's a lot better than last week. So so let's go to Step three, the antigen presenting cells that do this, also do another job, briefly, which we will get into in some other episode, or will bring a better person to do it. Some of those cells go to the lymph system, where they then activate the adaptive immune system where they form antibodies.33:56 Very, very important,33:58 relevant right now, because if everybody's running out getting a vaccine, that's what you're working on worthless unless you have this optimal.34:04 Yeah. 100%.34:06 So we won't get into that. But guess what functional foods polyphenols do?34:10 Oh, you don't even tell me that. They also work on that side. They also work on that. It's almost like your body wants polyphenols.34:16 It's almost like your body wants polyphenols. And of course, while we're at it, I mean, it's like it's almost like no, no, now he's just going overboard. No, no, I mean, it's, trust me, I read every article. It's like I feel like I'm making stuff up. Now. It helps produce interferons. It helps control the toll like receptors.34:43 So means you're just a side note. interferon if anybody's ever dealt with early stage, melanoma, I mean, there are various cancers that you actually had to end up getting injections for interferon.34:54 I did I really thought you're gonna go if anybody's ever dealt with herpes. Now I'm dead serious. Yeah, like Libya isn't interferon?35:02 Absolutely. It isn't interferon. I'm just saying I guess what I was going is, is that35:07 if you've ever dealt with herpes, you kind of looked at me like, no.35:11 That's how I felt.35:16 But this is true. So drugs do this. You're exactly right. chemo drugs and drugs like a cycle of beer. They're their interferons. Yeah, because they block viruses. So polyphenols help increase the amount of interference when it's necessary. Correct. And by blocking the toll like receptors and controlling that. They actually decrease nuclear factor Kappa beta nfkb. We had that talk with Brocelite. So polyphenols and sulforaphane block, NF Kappa beta. So35:46 I was making sure that you're making contact with the people in the room. Do you think I was I was waving over somewhere else?35:52 I thought you were having a hallucination. So all right, so we blocked NF Kappa beta, which ultimately we know does the most major thing inflammation. So we've been saying a long time that the Mediterranean diet is an anti aging, anti inflammatory diet. Yes. This is why when Adele did her sert diet, this is why it works. You decrease overall inflammation, definitely the whole process. And because, oh, I skipped a little step here. But one thing that we always talk about is the potent antioxidant effects.36:33 Yeah, I'm glad you're getting this part because we're going to augment this little section here, too.36:37 Yeah. So tell me what you got to say about antioxidant.36:39 What is it immediately takes me back because ROS is something that Joe botel and we've referenced her on the show multiple times. But when she was talking specifically about long endurance athletes and how they get injury, and how certain people who are high performance athletes get injured and have a difficult time recovering, it's often because they don't have good control of their RMS or reactive oxygenation species. you're pointing at something, but I'm not on camera. Oh, I am now. So there we go. I didn't know that. There's no red lights in here, by the way. But I find that to be a really big key aspect about rlms. And what polyphenols do because she specifically said to it to decrease healing time and increase optimal athletic performance, high polyphenol concentration, or normal amount is a must, and that our bodies are simply waiting on enough polyphenols to do this job.37:34 Yes. 100%. So now the final part here is more of a vague, you get a picture camera now to fix the camera. You can't take me by surprise anymore. I mean, we can hire Mike to find our to find our podcast sponsors, but we can't even hire a good audio visual guy.37:50 I don't think that hot dog company comes with that.37:56 Alright, so we get down to this last thing here, which is chronic disease. So what we talked about low level inflammation. This is how you can protect yourself against heart disease, cancer, aging, autoimmune dementia and obesity. And I put this one up as a general one, because we mentioned it a little bit, I want to talk about it right after this, about how large stable polyphenols I found an article that showed the more hydroxyl bonds on the outside, more beneficial is. That's why when we initially were developing Atrantil, and Dr. Bruce Burnett looked at this and said you picked the perfect poly phenol to be the most bioactive and most diverse.38:37 That's all he does. There's there's more points to do stuff. It's like more surfaces. It's more38:41 surface area. Exactly. And then in addition to that, we know that in all these articles, so if you're somebody you're like, Oh, I already take tumeric. I already take quercetin and that's awesome. Keep doing that. Yeah, keep doing that. But you have to understand something tumeric and quercetin don't get directly absorbed, they actually have to go to the microbiome where they get broken down into the metabolites. I've got articles to show what is the effective metabolite, of quercetin. So when Dr. Mark was talking about that, I want to tell him, that's awesome. But you better make sure that you have a good microbiome. So what this represents is the prebiotic ability of polyphenols to diversify your microbiome so that when you take these things, you're getting the appropriate we're gonna call them the appropriate metabolites. I call them post biotics, but we're gonna call him the appropriate metabolite.39:31 It's a honestly it's kind of like if, if you look at the way that he talked about ecgc, and, and tumeric, and trying to enforce it and etc. He broke all those down and talked about their beneficial natures as it pertains to inflammation. But what you're describing, if I can kind of put it into layman's terms, it's almost as if that is great. And you can get an Uber to have that delivered to somewhere and you hope it's a great car and you hope It gets you there comfortably. But in order for it to be effective and get there on time you want a private car you want the limousine. The limousine is the larger molecule, the all natural, larger parent molecule, if you will, kind of like what's in Atrantil and abbraccio to do that,40:17 exactly. So what you want to be able to do and what we're saying is not just supplements. Now, this is why you want to have a very colorful plate. That's why you want to have lots of fruits and vegetables. Yeah, continue to do that. Try to do every non GMO foods and vegetables. But when we're talking about polyphenols, very few things concentrate polyphenols, so when you're like, Oh, I heard Dr. Oz talked about reservatrol polyphenol. Oh, I heard someone so talk about Kirsten, polyphenol. Oh, but you know what? I drink green tea, polyphenol. Yeah. And they all get broken down. Here's what's fascinating. And I can't wait to do this. When we have Dr. Sylvia on her research is showing that you can produce quercetin egcg, which is green tea extract. You can produce the metabolites of curcumin and all these things from larger tannins. Yeah, that's what I mean, this is so fascinating, and your body knows how to do it. And you know what? I mean? Do me a favor, when you get done watching this, go to COVID? episode number two, because we did that in March. Yeah. And we were right, because we talked to scientists all the time. We're always doing this. So Sofia said, You know what, I'm gonna challenge you not to we will share the mic even though the You and I both been tested, like yesterday. Yeah, for COVID and we're negative, can you walk through and just explain what each one of these days does really quick, 41:30 I'm going to try Okay, so that a right there is going to prevent the virus itself that a if there's for the gut microbiome, that a I believe is going to prevent it from binding to that set of cells, that one is going to function as a zincionafor prevent or allowing zinc to go in and stop the replicates that is a mast cell that's going to help control the number of goodness gracious, I guess those little inflammatory markers that are going to go to the blood vessel braided cinans kind of There you go, and then be circulated which of course, we're going to regulate the amount of fluid that's going to leave the bloodstream and we're going to stop the amount of flags are gonna pop up as appropriate. Orders one, Oh, that one is a phagocytes, that's going to improve the the maturation of the phagocytes the one just below it is going to help the phagocytes since they are maturing more quickly, it's going to allow the them to display quicker and then it's going to regulate the number of cytokines which is TNF alpha, IL six, IL one and il eight. And I don't know if I'm gonna go through the mechanisms of those but that's okay. Oh, yeah, good, quick. TNF. Alpha is for the brain. IL six is for the bone and it's because of white blood cell maturation IL one is for infection and inflammatory things that come from the liver and i l eight, is what is going to basically start the cycle all over again, where the fluid is, is being summoned and redness, swelling and pain.42:55 Excellent. Stage three.42:56 Okay, that's the presenting. Yeah, it is. And that's where the cells dying, we get to oxygen a oxidative stress. Yeah, it says that. But we need to control our ros because it's not the RO S is bad. Too much ros, though, can lead to long term heart disease, cancer, aging, autoimmune dementia, obesity, and adaptive antibodies, we aren't going to go all the way through there. But essentially, aside from the innate immune system, we need help in the adaptive immune system as well.43:28 It would be fascinating to see what the antibody levels of people that are vaccinated if you're scientists out there on your on your cool study will supply you with some big polyphenols and see if people mount a better antibody response. If it lasts longer. These are all just fascinating questions. What's this?43:45 So when we get over here to TLR, we this is what is going to function as another flag zone, where we're going to signal the liver to then produce interferon, which functions to fight cancers and all kinds of different things like that. And then we have NF kb. We've talked about this extensively, whenever we had Brock elite on the show, both john and David was gonna say, Robert, but it's David Roberts on the show. And essentially, what we want to do is not have this gigantic burst of TNF alpha, and IL six because it's just going to turn into more inflammation. And again, Polly finos once again, aren't going to abandon you. They're still going to work even on that end. Okay.44:32 You're so much smarter than I thought you were. Nice job.44:36 I just remember a lot.44:38 Can you hear me on this one?44:39 Yeah, yeah, that was never good.44:41 You can probably take the headphones off now to show everybody. So did that make sense? I44:47 think it makes a lot of sense. I mean, it's a lot of information. Not everybody is going to just readily walk away, like we just did from it, but watch it several times. I think though, really what we're trying to show here is that We don't want to just say that we don't want to just say that polyphenols they'll work with with viral or bacterial infection. This is something that I wish more people would do you tell me that something works. Just explain how show me how how do you know that it's going to work? And I'm not saying that people don't have markers or blood enzymes or circulating things that they measure, they see things go down. That's important that lets you know that we're on the right track. But this kind of stuff, this kind of research that you've been sifting through with Angie, is just awesome. Because now it's almost like putting a name to the face. We can see how it's working. Exactly. So I think it's important. 45:41 And this doesn't just stop here because you know, Angie's episode, people, it's really being shared a lot. Oh, yeah, just people if you have pots or Ehlers danlos or CBOE or anything, people thousands of downloads on the podcast, by the way. Yeah. And she describes how when you have NF Kappa beta up, yeah, you're gonna have decreased acetylcholine when TNF alpha like this is all the balance in that. Yeah. The key is to see the colon whenever Yeah, but that's a whole separate conversation. This is strictly on the innate immune system, right. And so I find it fascinating. I find it fascinating that when I listen to another doctor talk about this, and I'm like that I very much like, very much like me, like, I'll listen to stuff and the patients will ask me, they're like, hey, do you know about this? And I'm like, I don't have the bandwidth and the time to do it. That's awesome, which is why I kind of tasked or I didn't task. She did it on her own, which is why Angie learned so much about dysautonomia, like I just don't have that in me right now or the time to do it. And she crushed it. Yeah. And one of the what we've been emailing, she's been emailed by so many people, she's gonna keep going, she's gonna end up writing a book and probably saving a lot of people. And so this is this is first step, innate immune system. I tell all my patients, let's exercise a little I don't care what you do, just get up off the couch and move around, right? Doesn't really matter what, don't eat highly processed foods, like high fructose corn syrup, soybean oil, anything, you're open in a package, read the label, because that breaks down that Mary, Mary Mary first step, which is gut health. All health begins and ends in the gut, definitely. And then get your polyphenols, get a little sun, get some sleep. Do you do that? That's better than what's better than most are doing.47:32 I mean, it really is. And it's, it seems complicated. And but in the end, the actionable items really aren't that complicated.47:41 I mean, when we're in some weird times, I mean, let's be honest, we're taping this episode. The day after we had that weird thing that happened last night or yesterday where47:51 you didn't get your change back at the store. I didn't47:53 get my change back. I'm still upset about that. The lady was clearly distracted, because apparently our government was overrun by48:02 Oh, yeah, that was a big deal. Yeah.48:05 And so these are stressful times. Yeah, we got to keep the inflammation down. There's nothing to cause inflammation. Yeah, don't, don't bring it upon yourself. Don't eat bad. Don't lose sleep, and make sure that you get your polyphenols.48:17 To my knowledge, polyphenols won't directly help bad politics, but maybe those politicians could use some more polyphenols and they wouldn't act so crazy.48:26 Oh my gosh, don't even get me started. Because what I want to do, and I believe that this will be the future we're gonna be sitting here 50 years from now we're gonna look the same because of the anti aging qualities of polyphenols. The 50 years from now we're gonna be like, wasn't that great that they put psilocybin in the water so that we all treat each other nice. You know? It's so you're just gonna pull up instead of Starbucks, you're gonna pull up to MDMA cafes? And I'm not kidding. Like the research on that is like, we're gonna go there also. Yeah, there. Somebody joined at baby bathwater Dr. Raven, I was reading his profile, really cool. And we're gonna I'm gonna try to bring him on here. But he's got a device called an Apollo device, which vibrates when you're not breathing appropriately, which means if and we're gonna do a whole episode on breath work, and we got our we just got all kinds of cool stuff to do. But you can't, you can't leave this hanging like, this is important. Look at all those. Look at all those one last time here. Let's just look at the amount of places.49:29 Places I'm just counting right now. 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 19 20 looks like there's almost 20 things out there49:40 that I found in a guy like Bruce Burnett, sitting at home, he's like, there's 38 you're missing the critical ones. 38 on line one. I know. Well, this is this is what you get when you let a doctor try and try and try and describe this.49:54 Yeah, but seriously, I think the takeaway here is that we can put there's no Muscle behind the message there, it really does work. And this is not specific to any one virus or any one bacteria. This is what your body needs in order for your immune system to work efficiently just so happens, that it works really, really well for what a lot of people are concerned about.50:18 It does and you just came up with a whole new idea. But as we close this out I think I'm gonna attach this next time I do a hemorrhoid on a patient so we can hear50:27 the hemorrhoid. Be sure that requires some type of consent. But yeah, I think it's awesome.50:34 All right. So thank you, everyone, for listening to this. I hope that this is something that makes some sense, please share it, subscribe to the YouTube channel. Subscribe to the I guess all the other platforms, iTunes and Spotify and 50:52 we are honestly the run on Atrantil at the KBMD store has been kind of intense over the last two months. So number one, thanks for everyone for sharing all the information here recently we're doing all that we can to bring that part back online but we'll have an associated discount probably with this particular show. Just in general with with the immune system. Yeah, and as soon as that rolls out, then we'll make that available and all the show notes etc.51:15 Totally and thank you diarrhea dogs for this episode go to diarrhea dogs.com put in code Mike for a 98% discount.51:26 I can't wait to find out what people email in and say what's it diarrhea dogs.com.51:33 Remember, it's code Mike, for 98% discount.51:39 I think it's probably gonna do it for us. Thank you all for joining us on the gut check project please like and share and we will see y'all with 48 with some continuation on the immune system. Talk to you then51:49 bye bye. Thank you.

BrocElite: Naturally Anti-Cancer...

Play Episode Listen Later Nov 5, 2020 74:40

0:00 Hello KBMD health family and gut check project fans welcome to episode number 44. This episode's very special because we have is many of y'all know with my co host here, Dr. Kenneth Brown, he's only selected three products to be a part of his own store Atrantil, and CBD Of course, which has his own KB MD CBD label on it. But today, we're actually only going to talk about one. And that re ally was shot through seeing. So see that but this is0:32 Broc Elite today.0:33 It's all about Broc Elite. These are stable sulforaphanes. And we are joined with David Phd. No, David Roberts, John Gildea, saying that's why that's why I have a co host. That's why he has me one of the to David Roberts and John Gildea, john, good day being the PhD for Broc Elite. And Welcome, gentlemen, thank you all so much for meeting us this afternoon.0:56 That's your tip. 0:57 It's good to be here. Thanks for having us.0:59 So john, is if you're looking at the YouTube is the first voice that you heard in the purple shirt. And then David is the one in the buttoned up. So hello, there's David. So, Dr. Brown, you want to take us into the fourth year of introducing these two?1:13 Absolutely. So all the only reason why I have three products on my website is because it's three products backed by science we do certificate of analysis and all these things we were introduced to Brock Elite through baby bathwater networks. And we had our first zoom call many months ago where I have been so excited about sulforaphanes as a supplement and finding out that these two brilliant men figured out how to actually make what I tell my patients is the world's first stable sulforaphane developed in science and been able to show clinically and through laboratory testing that you can increase the NRF two pathway. Now you and I did a whole episode on NRF. Two, in anticipation of trying to get these two guys together. Correct, which like typical entrepreneurs, and typical PhDs, they got a lot going on. And john did inform us I'm sorry, john, do you go by Dr. Gildea? Do you go by john? Do you just go by Dr. Brock elite?2:23 My dad was a physician. So I I'm fine with a PhD John. Not a physician. So yeah, the doctor.2:34 So when you write that when you write PhD, John, do people come up to him and go, John, John, your appointment is now available?2:44 Yeah, some some some of my students call me dr. john. But that's, that's just them being kind of silly.2:50 Well, this is something that is not silly at all. And what I'm really excited to talk about is how you guys got here, how you guys got to know each other. But I know that we have a little bit of limited time with you as the PhD. What I want you to at least explain while we have some availability with you, is why you decided to help David, develop this product and the lab that you have that?3:21 Yeah, absolutely. I think the at least the crux of it was that when, during a commercial adventure that we're trying to do to figure out how to do personalized medicine. We have an arsenal of of compounds that we would try by culturing the cells from New grown from the person who had the cancer and then and then putting these bevy of pharmaceutical compounds on the, on the cells. And pretty soon after we have been doing that for a while. Sulforaphane kept on coming out really high on on the on the list, and it's because it attacks a specific type of cancer, cancer stem cell. And I know that's not even on people's minds right now. But that is the cell type that goes on to create metastasis. And we're all surprised that there wasn't a sulforaphane product out there. And so that combination of seeing this gigantic need, working with people had these cancer stem cell driven, driven cancers. We weren't we we knew that you know, you can buy the $650 for five milligram sulforaphane from from Sigma but that way, you know, one treatment would have been, you know, 1200 dollars to give person that. And so that was when we started trying to figure out how to make it and stabilize it. We grew up broccoli sprouts for a long time, got really good at that. scaled it up enough so that we could help help out one person at a time really. But, you know, from that we started down the journey of trying to figure out how to make it into a pill. Because a lot of people can't can't eat, you know, the, the cup of broccoli sprouts, that's necessary to get the right dose and, and so worked on that for a long time and then and then figured out how to stabilize it.5:30 If you don't mind just to kind of paint the picture here. If everyone's not caught up. Brock Elite i derives its name because it's from broccoli sprouts, and it's elite because correct me if I'm wrong, john, but you essentially have the only stable so fear of fame delivery system available in capsules, in other words, and in other terms you can find so if you're a fan of different supplements, etc, on various platforms, some that rhyme or sound like a jungle, and they probably aren't the same. or certainly don't perform actively, like what we would find your broccoli does that correct?6:09 Yeah, so the this sort of, I would guess the marketing hitch here is that they re coined an old name. The precursor to sulforaphane is called glucoraphanin. Correct. And so they changed the name of that to6:29 sulforaphane glucosinolate. Yeah. Okay.6:32 So that is the new marketing term, okay, because we're gonna I went, when I tell my patients, the first thing that they do, I say, Listen, I really think that for whatever reason, and I have a bunch of medical reasons why I want their NRF two pathway to go up. First thing they do is go I went on Amazon, and I found this sprout product that's $12. And I'm like, that's glucoraphanin and then that takes me down a rabbit hole. Can you just explain really quick, why glucoraphanin is not the same thing as so perfect.7:00 So glucoraphanin is stable, and it's waterside long. It's relatively easy to isolate. And has been available for a long time, but you have to convert it through an enzymatic reaction. In order to make sulforaphane but then the sulforaphane is unstable. So you can make it all you want, but it's only going to stick around for you know, a day or so. So you can't put it in bottle and package it and get it out there. So that was that was sort of the magic because it is making the stable sulforaphane. And also along the way we were we're testing lots of other cruciferous vegetables and sort of the the added benefit was that we found that process that we landed on actually stabilizes all the, the isothiocyanates that's the term for all of the ingredients in in these cruciferous vegetables that are good for you. So like, you know, bok choy and, and watercress and, and cabbage, they all have their own individual combination of isothiocyanates. And so we found in testing in the laboratory that sulforaphane and another isothiocyanate from watercress called PITC act synergistically. And we basically used the most stringent test that you can do in order to measure for synergy. Just dilute the dilute the one compound sulforaphane until you see no response. And then you you dilute the PITC. Until you see no response. And then if you combine the two, and you see your response, you know that it's synergistic. So actually, the two primary compounds in our product acts synergistically. So even if someone else had a for fame, stabilized product, ours is going to outperform it.9:05 That's awesome. So the beauty of this is we're leading with the science first because we're going to spend the rest of the time talking to David about the history how this all came to fruition and everything, which I find to be a very fascinating story. But it's a rare opportunity to talk with somebody with your knowledge about how you discovered to do these tests, and which is what I it's just it's so exciting to me that I could sit there and say you did these tests, first in a lab. So as you started to do this, did you have access to the lab immediately? Did you build anything as the business was being developed? How did you augment from a scientific standpoint, the whole process to try9:49 probably ferret out within more but9:52 we have a lab in my house.9:55 I really get really9:58 not That's10:00 actually Eric actually makes propofol in his bathtub. And that's what we use to sedate our patients so fully understand that. That's not true as a joke.10:15 It does not say that on the permission slip.10:19 We actually, when we were doing wanting to do personalized medicine and not the shotgun approach, we purchased a decent amount of equipment we had in order to do cell base studies. And we did this actually moved all of my boys, my boys play room, they were three and five. And we moved their toys out in the lab in the playground. So10:51 I'm sorry, I'm sorry, David. JOHN, just real quick, I know that I just wanted to grab you before you left. But chemically and speaking as a PhD, obviously, the reason why you've turned to broccoli and other cruciferous vegetables is because of what they had inside of them. Correct. And so if people consume broccoli, or cauliflower or Brussel, sprouts, etc, they essentially are a part of that same family. But what happens specifically, if someone were to want to eat them, whether mature or youngest sprouts, and then whether they be cooked or raw? And then tell us a little bit why it's kind of an incredible discovery to be able to put sulforaphanes into something like broccoli?11:37 Yes, there's a lot of papers that delve into the try to optimize getting sulforaphane from broccoli, where, you know, they talk about how many minutes in, in a, in a microwave or, or steamed for a certain amount of time and things like that. And suffice it to say it's just a, it's a give and take. So the enzyme that will create sulforaphane needs a bunch of cofactors for it, and there's that forward reaction, but there's also reverse reaction, and you're always in a compromise. So it's being created, and it's being destroyed all the time. And, and sort of without getting into the specifics of it, we figured out how to make it only go to the right and, and and then afterwards, it's it's stable. So anytime that you're eating any cruciferous vegetable, you have to crush it and eat it so that you're releasing the precursor glucoraphanin to get in contact with the the enzyme12:52 morosa burns from Myrosinase12:54 Marissa. And then. And then the problem with that is that as soon as you eat it, they're your digestion will destroy the enzyme. And that's the same problem with consuming a pill that has the enzyme. And the precursor is that you know, a good portion of that enzyme is destroyed, because it's a protein and most proteins are digested in during digestion. So there's not much Myrosinase around to convert into glucoraphanin precursor into the final product. So yeah, that's the that's sort of the Battle of everyone is is doing and you do get some and but it's it's that reverse reaction that's kind of really blowing it for everybody.13:44 Well, something that sounds really interesting to me is is that I know from talking to you earlier that y'all basically put put it to the test where we can theorize how things work in vitro, but you're able to deliver and use broccoli and tell us about how you're able to actually test the levels of the bioavailability of severe things. That way, we know that it's actually getting to where we want it to work.14:08 Yeah, I've read at least I think I've read just about every paper out there on sulforaphane. And I never saw a paper that actually shows that it's working in a person, you know, other than whatever the clinical study that they're using. They saw, you know, changes in the clinical study. But the actual about chemistry test is to see that the interest to the active molecule is to accumulate NSL and translocate into the nucleus. So the test that we did was we took just a normal dose of of our Brock Elite product, and then in a couple of hours, we isolated cells from the cheek swab and then did beforehand and after after taking the product. And measuring by immunofluorescence, the cumulation of NRF, two in the nucleus and showed that the dose that's in our pill actually caused an induction of NRF. Two in in cells and a person. And the nice thing about it was that you can take those same cells and do an invitro assay in a dish, and then put on the pure sulforaphane, you know, the $650 per gram, five gram from from Sigma. And then do this thing, do a titration. And say, how much sulforaphane at that cell creates this response. And actually, the, the amount of sulforaphane that was put on the cells, five, Mike, five micro mole produced the same amount as our oral Brock Elite that we took. So we actually know that the amount of sulforaphane that gets to the cell, or the sulforaphane equivalent is at five micromolar, which is an amount that has been shown in you know, thousands of papers to be functional.16:14 So in essence, they were able to show that they could activate NRF2 pathway.16:17 Yeah, so dr. john, let me ask you, when you did these studies, and I, I know that you even tested yourself when you were taking it and you checked it, what was the timeframe like the the area under the curve when it finally popped up? And you were able to show that so I'm thinking from a gastroenterologist standpoint, where does it get absorbed? How much it's broken down? That kind of thing?16:38 It's been it's been a little while since I did it, but I think it was, is either two or four hours, two hours. And from the literature, you people have measured sulforaphane in the bloodstream. Fahy group has done it from serum a number of times and measure the actual molecule in blood. And, you know, its its peak is around, you know, two to four hours. So we knew that that would be a good place to start. And so we saw a really robust response. And the first time we did,17:15 and I don't remember if it was a fakie article, or one of your articles, but you did show that the second dose had a more, as you say, robust response. Can you discuss the big dosing?17:29 Yes. So the notion behind that is really interesting. There's a number of mouse studies that show that not only just get interrupt to induction through, you know, the separation NRF two from keep one, so that it's it's enough to become stable, or it's blocked from being degraded. But one of the things that people don't know is that NRF two, regulates its its own gene products. So when you get an RF to induction, it goes and turns on the transcription of NRF. Two, that's a It's a unique molecule on that, when NRF two is turned on, it goes back to its own promoter and self promoter. And even beyond that, after you get this induction that stays on for as long as 72 hours. There's even another level on top of that, which is epigenetic, just kind of where the name of our lab came from. episodul ABS it's an epigenetic I mentioned. Nice. Yeah. interrupt to stays on as long as as much as six months after taking it for18:43 weeks. Just really quick. Just explain what epi genetic response means.18:48 Yeah, so genetics is, in general, what you would think of is, say you had a mutation and Gene, you get a phenotype in the DNA? Well, a lot of biology is actually created by the expression of the RNA of the whole plethora of genes expression in sort of the orchestra of what a cell is supposed to do. And epigenetics is the maintenance of transcriptional on and off states of a cell. So you can change the, the on and off state of a whole bunch of cells for the long term after you stimulate sulforaphane for just a matter of weeks. So that's kind of one of the brilliant things about NRF two.19:35 So you had we had discussed this and you use the term I believe it was pleiotropic. we're describing because it almost seems too good to be true. But now when you say it's an epigenetic phenomenon, when you turn your NRF two pathway on, there are lots of downstream positive effects that can happen. And do you believe it's the epigenetic phenomenon or is it just turning Get on with the body, then does the it has so much it's um, you know, the NRF two pathway, we did a whole episode on it because it is it. It's something that nobody's talking about you guys are discussing it on a cellular level, which is amazing, which is why I really like everything that you have done, you started with a lab with the science working your way back, and now it's become a product in a bottle that I can give to people. So the whole aspect of my saying it right, pleiotropic? Or is that the right?20:34 Yes, pleiotropic is a term used to cover this idea that NRF two turns on numerous classes of genes. So it turns on a whole bunch of genes that regulate detoxification, and it turns on a whole bunch of genes that are antioxidants. And then yeah, there's there's numerous groups of genes and, and then inflammation as well. So NF Kappa b. So being able to turn on those three different pathways that are all in all three of them are involved in many, many, many, or maybe all chronic diseases. This is sort of the magic and the juice. And that I think the other the other aspect that a lot of people don't realize is that, you know, the reason that reactive oxygen species became famous was that it did long term damage, and everyone knew that it was involved in chronic disease. Well, now in sort of hindsight is when you get hydrogen peroxide, or a lot of these reactive oxygen species being turned on I it at times, like viruses are known to turn off interested. So the actual thing that is broken, that is causing the chronic disease in the first place is low NRF. Two, and then turning it back on, obviously should should help a lot of those states.22:03 And I love that you describe the whole how you figured out that murasame as the the enzymatic pathway can go forward or backwards, very similar. If there is chronic inflammation, it can shut down the NRF. Two, when really when you have chronic inflammation, you got to figure out how to get that up to stop the chronic inflammation. So I have this discussion with my patients that have either the propensity for autoimmune disease, or they have an autoimmune disease. And I try and explain it that I really would like a combination of a polyphenolic blend plus Brock Elite so that we can tip that scale back. So your NRF two can come up. So that it's sort of the seesaw of that. So that's the way you describe them Ross is going back and forth. It's a fine line. And as a society, I feel like we're all chronically employed.22:53 Yeah, that's for sure. And then that that balance that's going on, that's pretty well established in the autoimmune disease world is that there's, there's some event that precedes autoimmunity. And whatever it is, whether it's you know, have a season without sleeping, or you have a viral infection, or you're, you know, someone in your family died, you know, they're all manifests the same way they it's, it's a genomic instability, inflammation, in all these processes that are involved in basically every chronic disease progression. And what's interesting is those those exact things are the things that you have to address to reverse any chronic disease. So, you know, a good baseline to start from would be to activator and f2. And like you said, you know, probably just following it would be NF Kappa b and inflammation.23:58 One One quick, hopefully, it's quick, but it may not be. There was a paper or study that came out last year that the Ken and I both ran across that talked about that some cancers, try to essentially commandeer the NRF two pathway to basically kind of shield themselves from from destruction, and that way they kind of hide what kind of role would so if you're a vein supplementation, play in this where the NRF two pathway gene, or that expression is somewhat mutated, is there? Is there a role where severe pains can basically return us or? I don't know You take it from there.24:40 Yeah, I've thought a lot about that. That role in general is, you know, the selfishness of a cancer. And, as opposed to a normal cell, which is, you know, thinking globally, it's, it's, it's trying to protect the whole organism that you surfing of f2 is, is basically, if you can ramp up your detox of a single cell, basically, the reason that that is, is such a bad thing is because you're throwing toxins at it to try and kill it. But if that cell is now robust, in that, you know, those two man, you know, detox machine at that point, then you know, those toxins that that's how you define successful, you know, treatment of cancer is that cell is, is not killed by the thing that you're throwing at it. That's how you define it. But basically, you know, we haven't found a cell line yet that if you throw so forth, and added it doesn't kill it so so that that specific scenario that you're describing is very true. And, and is part of the mechanism of cancer progression. But it isn't, it isn't this in a holistic way, NRF two works in a normal cell. So all the normal cells are going to be fighting to get rid of that cancer as well. So now on both fronts, it kills the cancer and it's making the cells that normally are working against the cancer, or better your immune system, your support cells,26:21 especially the cells that are not tainted are the ones who are able now to better defend themselves by having a stronger interest is mutated on26:30 that whole, that whole business of, of, you know, hijacking, blocking the immune system from getting to the cancer. So is also another aspect of of, you know, having a really brilliant immune system if you're trying to fight cancer.26:46 Sure. No, that makes sense.26:49 It's interesting, because as I've been using this in patients, the comments that have been told to me, so I'm trying to tell my patients you've got you're at risk for XYZ, cancer, autoimmune, and then I've had people come back and they purchase more, because they're like, you know, it's really interesting, giving it to my husband who has early dementia, and he appears to be doing better with it. And I'm like, that's interesting, okay. And then I can say, well, that would make sense from an if you increase in RF too. And once again, we're not saying that if you take a supplement this happens, but we do know that if you can increase a pathway known as the NRF, two pathway, then this can do certain things. So I'm seeing success with my patients in neuro inflammatory processes, which is a lot of things. I kind of got a giggle a little giggle out of this, because I heard David on a podcast, and he was talking about sleep and increased dreams. And I am a total believer in that. It's part of my sleep routine. And I'm putting people on it for sleep. And I don't I don't wear my aura ring anymore. I used to but because now I just I wake up and I'm like, Whoa, those are some cool dreams. Yes. And so they're asleep. And I'm like, how in the world does that play into that? And then from a gastroenterology standpoint, I've got two patients that failed multiple rounds of heavy antibiotics to treat H. pylori. And then ultimately, I'm like, Look, if you want to try something natural, and we do atrantil to plus Brock Elite, I'll try and teal is a poly phenolic blend that has some antimicrobial activity. And then broccoli when I heard who's the guy he just mentioned at Hopkins, that Fei Fegi, he had discussed that they have done some research on directly with H. pylori, and I've got two people that failed multiple rounds of traditional antibiotics that are now clear. Oh, okay, this is really cool. Like, this is some really neat stuff that's going on. And as I'm listening to you, I love it. Because although it may be it may be a little overwhelming for somebody hearing this or it's just like, okay, I just want the public to know how much work and how much science went into it before it ever became a product in a bottle. And that's so commendable. And so cool. And I, you know, you are where'd you get your PhD? It was a school heard of John's Johns Hopkins? Is that hope instead of college? I think they've, I don't know, I'm not really sure if they play football. I'm gonna have to look at that because of a football. So you're so so you got your PhD at Johns Hopkins, which is no joke and all the people that have done a lot of the research on sulforaphane like fe II have done a lot of that and when you were talking about the cost of stable glucose, stable sulforaphane, that even they admit that they can't do a whole lot of studies on it because it's just cost prohibitive. So what you've done is you've put lightning in a bottle and Very impressive. That is so cool. And you guys continue to do research on this, right? I mean, thinking of synergistic molecules to put with it. That's nuts.30:11 Yeah, so definitely, always, always marching forward slowly. And definitely that target of NF Kappa V is a big one. We have our our list of compounds we really want bioavailable. So,30:26 just really quick, you've said NF Kappa b a couple times we hear about NF Kappa b when it comes to inflammation, and certainly in this pandemic, that we're in NF Kappa b plays a big role, can you just explain what NF Kappa b does downstream30:41 instead of NF Kappa b is the is the master regulator of inflammation. So inflammation is important in fighting, fighting a know your bacterial invasion, you get you you recruit your entire immune system to to attack a site and take care of an infection. The problem in the chronic disease state is that you get NF Kappa b. Induction, which leads to this cytokines released. And so even though there isn't an infection in this chronic inflammation state, your immune system is going and and invading that organ. And so the way the immune system works in that, in that case is it does a lot of damage just does bystander damage, inflammation and fiber optic response as well. So that's the that's the target is to try and keep this inflammatory state the chronic inflammatory state at bay that needs to be pushed back slightly. And sulforaphane does inhibit NF Kappa b. We measured it in, in urine and a clinical study measured interleukin six, which is a canonical target for NF Kappa b. So supporting does inhibit NF Kappa b, but there are molecules more powerful. curcumin is kind of high on high on our list.32:19 Yeah. I can talk more about that. I we should probably let John go. Given his32:25 Yeah, that that that we only have john for five minutes turned into a 20 Minute. Yeah, yeah. Yeah. I32:32 don't want to get him in trouble.32:33 Yeah. So much. It was great.32:36 JOHN, it was it was great. Again, thank you so much, and super impressed with all the work you're doing. And I love that you too, have teamed up you and David to produce something which I think is going to do remarkable things for people. It's certainly doing incredible things for my patients. So32:50 yeah, thank you. Yeah, it's, it's a, it's something that fell into our lap was the correct circumstances, where, you know, it's always comes from, you know, a need, and then someone who's precious to you, and I mean, a lot of powerful things happen from that.33:07 That's awesome. It's PhD john Gill day. Thank you, PhD, john. We appreciate it. And we're gonna hang out here with David with with rock elite as well, and certainly appreciate it. We'll have you back on again here shortly.33:21 Thanks. Awesome. Thanks, john. Appreciate your time. Yeah.33:24 Well, David, I've just been sitting there all quietly I know.33:27 So now this is the now though. Now the backstory? Yeah, let's figure out how in the world you got that guy to sit next to you in the first place.33:39 We're gonna be situate33:45 around centering the camera. Nicely done. Done. So David, all that science didn't happen for no reason. Yeah, here there is that there's a large story that brought you near and dear to what it is that you did to to basically found what is now Brock Elite. I don't care how far back you want to go. But just34:06 yeah. And and just for the record, I can't I do have a background in science, not like John's, but I can talk probably a decent amount about about Sulforaphane. But from because that's we talk about all the time, so and the backstory. My wife was diagnosed with breast cancer in 2012. And she was very determined to to treat it naturally. And at least not doing chemotherapy. And so we did a lot of reading and actually met john the first week, some of providentially and would talk to him regularly lay about papers I was reading. Anyway, fast forward. In March, our Mars cancer spread. And we're realizing that what we were doing wasn't working. And so we really decided we can't like, we get an excuse, we can't do a kind of a shotgun approach, we needed to know that something was working. And so we end up getting some cancer cells growing them in this lab we put together and and then john created this battery of supplements, to and what he would do is he put the supplements on normal cells, the renal proximal to the cells that we purchased, and then also the cancer cells that he was able to grow. And the goal was to kill the cancer without killing the normal cells. And so and so, yeah, software affine was was a top three and killing Maurice steps cancer, went to buy it, and then realized it didn't actually, it wasn't out there. So that was when we started growing. A lot of broccoli sprouts, brought broccoli By the way, Eric, you said, it's broccoli sprouts that we that that brought broccoli comes from the seed, so we don't actually sprout? Because it's, it's a it's a pain. Yeah,36:46 I've actually tried to grow it and it makes your whole house smell like.36:49 Yeah, it's, it's crazy. To be committed. So. But anyway, yeah, so. So we did that. And we would do some actually. So we have probably enough, we had enough sprouting material to probably 10 families. And so when you would use them with carrots and ginger and Apple, probably not Apple, but but everything was fresh. We threw some we actually all the the seat seats that we sprouted, we actually sprouted radish too, because it's back and radishes high and naturally high moroseness, which converts it. Yeah, everything converts. And then. So yeah, we did that for a long time. And, and, and it's kind of John's goal had been to stabilize this because as he says the literature was crying out for a stable form of the molecule. And so he kind of you would meet for lunch regularly. And just like, yeah, I think I have a stable form of it. And so can we get a test? I was like, yeah, so we get it tested at a third party lab, and found that we had it, you know, that he had stabilized it. And at that point, my wife was still alive and was like, we gotta, you know, this is amazing. We got to get this out to people because she knew how, you know how many people really needed it. And so yeah, that was that's kind of a, a portion of the backstory.38:40 So thank you for sharing that with us. So in 2012, Mara, your wife, yes, diagnosed. And then as you were trying to treat as a team, meaning husband, wife, she said you need to keep doing this. And during the, during her cancer process, you were trying to figure out this stuff. That's pretty, it's pretty emotional and pretty tough.39:05 Yeah. She did banned me from bringing journal articles to bed. I did that for several weeks. And she was like, Ah, so But yeah, I mean, you know, I have a science background. So it was it was it's, you know, she was going to she want to do it that way. You know, I wanted to support her the, our promise to each other was that it had to be backed by science. It couldn't just be loosey goosey. And and so, yeah, and that that's kind of how actually the our, our first supplement company or store was was founded, because we met the doctor who gave it to us and, and we were like, he was like, take this and like, well, what is it? It's like water. I don't know. But it's good for And I'm like, gosh, like, you know, I don't I just met you. So, so actually, john was able to figure out what it would what it did. And so we I bet it would be, first of all that what wasn't poisonous, you know? And then second of all, that actually is really good for you. So that was that was kind of the genesis of that as well. So So this all your endeavor into the whole supplement industry started with that, or were you part of the Restore company before or stars founded through what I just said. So basically, it wasn't even a story. It was a it was a, it was a white, unlabeled bottle that with a sharpie worked on it. And there's like, take this, and I'm like, dude, like that this goes against what we promised each other. This is like, there's no science. Sure, you know? And so, you know, you, you sound nice. But I'm going to figure out what this does before my wife takes it. Yeah. So then we found out that it was actually amazing. And then actually, that that comes with that company was formed.41:27 So were you the CEO, that company41:29 net. Okay, were you invited on personally, and then hope to get it off the ground.41:36 Because I also on a, there's there's a scientific aspect, which is really fascinating. To me. There's the emotional personal aspect, which is equally fascinating. And then as somebody who also is involved on a business side of a supplement company, that's also intriguing to me also, so the, how, how I made this sort of thing is exciting. from that aspect, going from there to here, going from there to have this that I can hold. Yeah, there's always,42:08 but yeah, we would. We would, you know, so you you got sprouts, they're strong, they're bitter. They, they're awful, actually. But they're potent, right. And so they're really good for you. And we would use them. So it wouldn't just be like a little it would be like, a ton. of and so it's like a massive dose. And, and once John, you know, figured out how to stabilize it, we would basically make these little basically would have a 15 lm a it was it was a liquid first. It was and and like a shot. It would Yeah, 15 ml, and this liquid extract, and then we put 15 ml of Lime juice and a packet of stevia, just shake it up, and then just down it. Like, I mean, and then we had actually another friend of ours, really could have benefited from that. I mean, she was really sick and couldn't take it. Mark could she could she could take it for the longest time. And then it just it but it's just, it's It was awful. So we knew we had to transition it into a capsule. But unfortunately, that happened after after Martha died in September of 2017. So we at that point shortly after that, you know, after we were kind of shell shock, kind of got it together and then figured out how to dry it and stay you know, in a stable risk. Yeah. So yeah, if you guys come to Charlottesville, you have to see a walk in and walk through when people walk through like, like, no, like, we made everything out like nothing. It's it's all unique. So44:19 so that's what makes it so unique and hidden sort of the proprietary thing and how it's stabilized is because you guys actually develop the equipment to do this and figure out the process and all44:30 that more process and piecemeal equipment it's already around Yeah.44:37 First of all, I'm sorry that your wife passed away and I'm commend you to sticking true to your path and having this as her legacy and the millions and people that you can help because this all started. Yeah, out of out of the goal to help.44:55 Yeah, I mean, we're we're hopeful that people are getting helped. And we do get a lot of testimonials not probably as many as you guys, but they they're starting to come in and yeah, and it's just like, Alright, that's, that's, that's really amazing to hear people and what they, you know what they, how it impacts them.45:22 So Brock elite itself, you're talking about the number of testimonials, the brand the label the the name when did this actually take foot in and get into this bottle for to be available?45:35 Yeah, that was we went to market in April of 2018.45:41 Okay. So roughly two years we're is we're in the late part of 2020 on this particular recording. And so in two years, you've, you've obviously linked up with with Brown and his clinic we've got, I don't know how many patients who've begun to take it now. sleep better, feel better. Do better top to bottom? What where do you see? How do you see getting the message of broccoli and the importances of sulfuric veins as it empowers one's NRF? Two pathway? Because it's a lot. I mean, it's unfortunately it's a it's a lot of it's a lot of words and letters and not everybody talks about.46:21 There's a we talked about this, there's so many similarities where first you have to explain a very complex, unique pathway that people aren't talking about. And we talked about this today, we're like, Why in the world? Aren't we talking more about the NRF two pathway, especially in the setting of immune health. And then the second thing is how in the world you climb over this giant wall of 2000 supplements that claim to do it. But we know just like dr. john mentioned that glucoraphanin is not a stable sulforaphane. So that's hurdle one is I need to explain why this can help you hurdle two is I need to explain why the $6 bottle from XYZ company is really not the same thing. And then hurdle three is this is a long play for you. So it isn't that your immediate ankle pain will get better, which is it's the Society of immediate gratification. So there's lots of similarities when when I deal with medicine, and I'm trying to get patients to stick to a regimen or something for a long time. From a business perspective. I'm curious how you're approaching that.47:35 Yeah, well, I mean, the great thing about broccoli is a lot of people take it feel the difference. B and john alluded to the kind of clinical a pre clinical trial we were doing where we did on aisle six. And so basically, we did a three day study, we did baseline, day one proceeded to, and then broccoli, day three is is blinded. And to fit your ends into basically from in, there's no change in our six levels from baseline to placebo, but there was basically 24 hours from taking the one dose of Brock Elite, a 30% decrease in Aisle six, in 24 hours. So that's enough, you can feel and that was one dose48:31 one goes decreased. So aisle six is interleukin six, which happens to be an inflammatory cytokine, which sets off a cascade Yeah, that currently, many pharmaceuticals are trying to block in this pandemic that we're in because we know that that could be the first cytokine that can set off a cascade. So it's fascinating that by increasing the NRF two pathway, it just puts everything kind of in balance.49:00 So So yeah, it works. I mean, they're they're, they're related, they're but they're two distinct pathways. So it works with NRF. Two, what does work with NF Kappa b as well and which is upstream from or downstream from IO sticks. And so, yeah, it works in both and but that's in the literature. And you know, we we have done our own internal but the great thing about so karafin is all the little I mean, there are already 2000 articles out there so it's like we don't have to really do anything I'm unlike with store, we had to we had to do everything you know, but with software event, it's already out there. And so you don't have to, you know, believe us we just can shoot we just Schmidt our main portal is showing that it's actually we have so paraffin in the in the bottle and the capsule and from you know from a marketing standpoint We're about to get over I think we've, it's, it's, we don't have a lot of the product because it's really backbreaking hard, it's hard to make. It's and that's why it costs so much, because it's we're kind of what we do most everything by hand. And we're transitioning as we grow. But, you know, it's, it's hard, it's difficult to make and, and stabilize, but it, but yet we're doing it and we're slowly figuring out how to scale it. But right now, like, we don't want to market time, because we can't, we don't have enough. You couldn't even supply our city, let alone and you know, and so. So yeah, right now. We are, you know, making it as fast as we can. And, and so yeah, the the drying process is is is for going through, look at the solid is difficult, and we think we've cracked the code on that is not a patented process. It's we decided to keep it traces trade secret ID six trade secret process. So that's hopefully was a good decision. But we figured, you know, it had been around for a lot of smart people for a pretty long time. So it's probably pretty safe.51:36 So something else to think about. And I don't want to make you talk off label about the brand, because we know that's not the kind of trouble that anybody wants. So let's just talk about sulforaphanes specifically. There is a different product, I believe it's used over in Europe, correct that they use for prostate, prostate cancer. Yes, prostophins. And then there's also some, some pretty deep studies that talk about lymphoma, there is the diffuse B cell lymphoma, as well as follicular lymphoma, which actually I've got a cousin who was recently diagnosed with that. So if your offense have been shown in repeated different clinical trials or studies to essentially activate that NRF two pathway to help those who basically have a managed cancer status. Is that something that else that kind of drew, maybe John to it whenever he began to test those cells, the cancer cells with the normal cells to make sure that so if you're if it was one of those compounds,52:44 is that what your question is?52:47 Kind of rambling? I just don't realize that. Like that.52:51 All right. Let me give the backstory today. We were sitting there talking, a cousin contacted him it was recently diagnosed with follicular lymphoma. And then his initial response was, Oh, my gosh, can taking sulforaphane help that Ben we found some articles which said specifically the treatment of certain Hodgkin's lymphomas and flicklock almost not not non Hodgkins. Sorry, non Hodgkins lymphoma. They have looked at sulforaphane looking at that. And so then it was one of those things. It's like, Oh, so I called up a couple oncology friends. And they were unaware of this. They're unaware of that pathway. And so for a friend being there, and it just it, it gets us, you know, talking where it's like, wow, this is something that the literature is out there, you just have to go digging a little bit somebody has done it. And it's, it's, as in this space, with the FDA regulated type thing. It's as you know, you cannot say certain things, but the, but the pathway is there, you're not53:56 doing laughing because he knows that it's hard to get rid of talk. This is what leads to rambling questions. I'm just gonna help Ken out, because now he's rambling54:06 down and you're like, why don't you? Yeah.54:13 So, you know, I can say that every cancer is different. And that's the bottom line. You can have two non Hodgkins lymphomas, you can have two, you know, breast cancers which are described medically the same that are completely different, right? They just are I mean, and so you know, John's put, you're talking about still purifying as a chemical that he got from Sigma Aldrich and then talking about cancer cells, not people you know, he's put a decent amount of stuff sheriffin Cancer cells and, and they typically it's not 100%, but they typically respond pretty well. And, and pathway wise. You know, there's, when you have cancer, you feel really bad, and there's a lot of inflammation that's going on that canister is shedding. And just just from that product that can help with inflammation would be great. If that was just it. That would, that would be it. You'd feel better, you know,55:34 really like how you said that reset each cancer, even if it has the same name can behave completely different because oncology friends, they've got protocols, and it's, you know, this is this protocol, oh, this person got cured, this person did not do another protocol, oh, this person did this. And then you start going down. I've never thought of it that way that just because we're calling it colon cancer, not all colon cancers are going to respond. And so you're exactly right. Each individual is completely different. I love the way that you guys started the business as a cell specific line. And can we make it as an individual treatment by taking the cells the fact that you took more cells, put it there with the renal cells to make sure it's non toxic first, then let's see what works. That's brilliant.56:23 that was John. So yeah. Yeah, I call John the cell whisperer, because he can grow like nobody, nobody, I really believe. I mean, this is not an overstatement. Nobody can do what he can do. And that the fact that he has a, he's just kind of manufactory. Yeah, to coat people swab and measure. And after he came up with that, you there's no nobody like you can read about NRF two be measured. But if you read how they're doing it, it's like an ordeal like, and he has a very quick, quick procedure that he came up with. He came up with the, his background before he went to Hopkins. He actually, if you guys remember the anthrax scare back in the early 2000s,57:13 mailing of the an anthrax,57:15 it came out he himself designed the five minute anthrax test, you could try, you can measure it. So that's sort of his, what he enjoys doing what he's good at is tests. So57:31 what do you enjoy doing?57:34 Wow, I love what I'm doing here. People are like, What's your dream job? This is it. I love the science, I love doing something that's worthwhile. And we're kind of peeling an onion, you know, because we know a lot probably, you know, we know quite a bit. But we're learning every day, every day about sulforaphane and you know, different things that we want to be doing with it.58:12 Instead, it's just very exciting. The smartest people are always on a quest for knowledge. It never stops. Yeah, never ever stops. But I will say, I'm going to pull the curtain back a little bit here, David, and that is that for every guest that we have on the show, we send out a questionnaire and ask various things like favorite drink and favorite band and different things like that. David left both of those blank. So I'm going to assign that your favorite drink is flavored Waterloo, which is mine also. And just simply because of John's work, I'm going to say your favorite band is anthrax.Yes.58:53 Awesome. So as you're peeling this onion recently went to your website, you got a few other products pretty cool you guys using similar technology and a few other which would typically be very on absorbable molecules, you're doing something cool. We got the perk elite, the berberine elite, and my missing one.59:19 Those those are ones that we're we've been working on. We're just plying for the patent for the curcumin one. So that will hopefully it was approved, your patent will start releasing that it's currently not for sale. But then, yes, and that that's really exciting. And the berberine so Berg leads, which I think we're going to rename but we'll see is a burn as with that because that but it's for you know, blood glucose. So you know people Kido just from my background with Mara, I was like the sugar Nazi. I mean, every bit of sugar was counted, you know. And so the goal was to have less than 20 grams a day. And so we early on people hate stevia, but, or stevia how everyone loves it. But uh, yeah, we, and we didn't like it very much. But now it's just like, it's what my kids have grown up with. And we don't just no sugar, no sugar, so the sugar is evil. So we're, we're just the berberine, especially at night is important because melatonin blocks your ability to if you have a night meal flexibilities for the, for the glucose to process, so that I'll just drop it. And so that's, you know, exciting. So we're, we're actually had that on the market and are doing some more testing to refine it right now. So it's not currently for sale, either our a little bit1:01:11 cellularly you're referencing sugar isn't? Didn't they say that? They don't have to gene actually can be mutated more rapidly with with refined sugars being present, isn't that correct?1:01:24 I've not read that. So yeah, I don't doubt it. I'm just saying I'm not. I'm not familiar with that study. So, so yeah, I mean, it's pro inflammatory. A lot of the refined sugars, if people ask me, there's one, you know, because the cancer with my wife, if there's one, one food that you just one that you recommend, stop eating and love, and I get that an ordinate amount? Like, I love the question because it's quick. It's just like high fructose corn syrup. 1:02:09 high fructose corn syrup1:02:10 there's corn syrup, the one thing I would say if you worry about cancer, don't don't eat things with high fructose corn syrup. And a close second is soybean oil, soybean. And that's in everything to so that today I just had ordered a organic hamburger from one of my favorite places and trucks. So I said hold the muster or hold the Manet's and hold the pickles. Pickles have hyper source corn syrup Manet's is made with with soybean oil. If you the reason why salads are so bad for you, it's not the lettuce, it's the dressing dressing less, it's organic, it's made with soybean oil. And so when the question comes, you know, I give them one thing, but I also go through things. And the reason both of those items soybeans, and corn from Tim, that makes high fructose corn syrup are genetically modified, the jag modification is there so that the plants can receive a roundup and not die. And that kills the weeds and allows in theory for a better yield of the plants of the crops. And most of the glyphosate gets washed away in the rain and stuff, but trace amounts get left on the plan. And that actually, because, you know, if you if you have one small amount of glyphosate, it doesn't matter, but it's in everything. And so there's this bio accumulation effect from being exposed to it non stop, and it actually your gut, your gut guy. It's insidious with the gut. A lot of actually had some friends move from Lebanon. And now that was like, watch out what you eat here. Because the food that you eat here, even though it's called the same thing, you're going to have got issues and they did. They're like, David, how, and then they get got issues. And then I'm like, seriously, and so they actually started watching what they're eating and refined. But glyphosate, the amount of glyphosate you can get in one fast food meal. It can drop your inner tube pathway 30% we mentioned that boom, that 30% basically turns off your ability to detox. So glyphosate is basically the mother of toxins that makes every toxin more toxic. And so That's, that's one of the pieces of research that john did. Like I said, also, we're talking about the ability for cells to connect, and, and can communicate through gap junctions. And each cell in the body is connected to other cells through a communication network called gap junctions, those gap junctions allow cells to be functionally coupled, they act like an organism versus individual cells. And so that's when cells lose their way, and become cancerous and that sort of thing, those cells don't communicate, and they lose their ability to act like in the organism. And so john also showed that the glyphosate reduces the ability of the gap junctions to communicate by 30%, or 30%. So that's enough that that lack of communication, all sorts of things can go wrong.1:06:11 So we don't need to eat anything that's GMO, we don't need to eat anything with high fructose corn syrup. We don't need anything with soybean oil. These are things that essentially what you're saying, David, if I understand correctly, these are things that could exacerbate or even introduce or stimulate cancer growth and cancer cell. The the the oncogene gets activated, basically, when we consume these kinds of foods.1:06:37 There's a Yes, yes. Yeah.1:06:41 It's bad. It's bad news. Yes. Well, David, thanks for fighting through about three technical difficulties on here. And thank you to Paul for who put all this together and make it seem seamless. What What an awesome product, I couldn't be happier for this to have been only product number three that we've brought to KB MD health. And it's something that I know that can I both firmly believe in? We love what it does, for those who who use it, including me and my family. And just thanks so much for the time, and thanks to you and your wife for having the the passion to do what you did here.1:07:20 Yeah, well, it's my pleasure. And looking forward to coming back on another point I do want to throw in, I will be talking about glyphosate. The reason we're doing that research was to show that sulfuric fen actually negates it brings or brings in our to back. So let's say depresses enough to but if you do play the glyphosate and so parafin brings it back to normal level.1:07:57 So if I go to McDonald's, and I say, hold the pickles in the mayonnaise, and then I just opened capsules of Brock Elite over the actual hamburger, I should be cool, right? No,1:08:12 no, we're not gonna but but and then also with gap junctions, that communication is reestablished with software offensive that the gap junction function gets re established so the that's the reason we were doing that those studies was to show the the insidiousness of the state but also that not to use it the way you just described that is actually a big deal. So but yeah, it's great to be here. Thank you guys so much for what you are doing in promoting health too and it's a it's a1:08:49 you know, it's it's really fun to talk to bench researcher like dr. John to talk to you that has an extreme passion to get this out there for the right reasons doing the right science behind it with the right motivation and then me as a clinician getting to see the one to one responses that I get from my patients it's it's it's an honor for me to look my patients in the eye and say, I know these guys did their homework. I feel like we at KBS research really try and science up the whole nutraceutical thing and make sure that otcs have a lot of science and you are both you guys are shaming me because the science you guys do is insane, Wow, yeah, that is awesome. I want to thank you for everything. Where can where can people connect with you? Where can they find Brock Elite, and so on. Yeah.1:09:44 So BrocElite.com and can go on there and we have an online store. So go ahead and buy it there. And we'll it's the best way to doBrocElite.com1:10:06 Yeah. And so I will tell everyone that's listening that as a clinician, I see tremendous effects with this. I am a little bit scared when you were saying it's a laborious process. And when you invited us down Do you intend us to put us to work when we come visit? Like you invite people to help with the laborious process?1:10:26 No, no, we'll just take you to some, some of our favorite restaurants that have clean eating,1:10:32 nice, clean eating and no and no mayo. Nice.1:10:36 Yeah, man. So yeah, and hopefully, as people are listening to this, maybe we can do a coupon code we talked about that as well.1:10:48 Absolutely. Yes. If you're if you're catching this podcast through video, or just if there's someone shared it to you go to KBMDhealth.com. Or just gut check project calm and you can connect not only with us, but David and dr. john Broc elite. We'll have all of those things available both in coupon redemptions, more information, data, data, data is what drives everything that David and John do. David, thank you so much everyone, like and share gut check project, Episode Number 44Transcribed by https://otter.ai

COVID-19 Files: Ep. 11

Play Episode Listen Later Oct 1, 2020 59:09

Eric Rieger 0:00 All right, it is now time for the gut check project with the COVID file installment number 11. I'm Eric Rieger, with your co host, Dr. Kenneth Brown. Dr. Brown what's happening today?Ken Brown 0:10 What's going on Eric? I love you sticking to your roots and the hair just keeps getting bigger and bigger this COVID do that. Yeah going on it's starting to starting to really rock right now.Eric Rieger 0:20 You can you can see roots you can see some gray Kevin but yeah, roots. Whatever it takes. Ken Brown 0:27 How have you been? What's going on with the family? let's get let's get caught up on that stuff. We're not doing enough personal stuff lately.Eric Rieger 0:33 Man family. It's funny. You mentioned that. Yeah, considering what we're going to talk about. But this weekend, I get to go and see my oldest he is in his first semester at Texas Tech. He's loving it, but I'm not seeing him in over a month can't wait till this weekend for us to say hello to each other and youngest Mac has got basketball this evening. They're doing tournaments. And of course, both of them are having to do this readjustment obviously around COVID. And Marie, I couldn't be more excited to to obviously go and watch the boys play. And then go watch or go catch up with gage this weekend. And she and I just remain busy. So it's a it's it's the world we live in now. It's prefaced by my COVID. What about yourself?Ken Brown 1:23 things are going really good with the family. We're trying to figure out how to get back at some of these tennis tournaments, as they put them on, and they cancel them and so on. So talking to mom a lot and trying to be very proactive about speak with mom trying to figure out how I can get my 79 year old, very Spry mom who's feeling better now than she did when she was 69. So and then 59. I think she's feeling better now than she has in 20 years. And so I started thinking about that I started thinking about family and how important that is. And this is what I want to kind of get into today today's I kind of threw you a curveball, I initially said we're going to talk about something and then I started going down these rabbit holes of research. And rather than rabbit holes, I'm gonna call them vole holes, the prairie vole holes. Alright, I'll explain how that ties in. But when we're looking at this, I'm sitting there talking to my mom, and she sounds great. And we're trying to do this. I've got, you know, we did some some zooms with some other friends around the country. And I'm like, wow, this is an interesting time. And I then started thinking about my practice. And I'm like, and my practice is really busy right now, like people are really struggling, and they're very desperate. So I started down this whole path. This is where it began. And this is going to end up being Angie Cooks podcast, because she's going to come on and I'm challenging her to be the expert in this, because I just got done doing Chris Kresser's podcast where he agreed, we need to bring this one thing out in the open. What we're seeing and what I'm seeing with patients is a consistent deal where if people have some sort of gastrointestinal problem, specifically CBOE, I can trace it back. And then you have these people that are showing up with dysautonomia, they've got pots. Ehlers Danlos and which comes first chicken of the egg did something cause that, if those terms don't mean anything to you, good. If they mean something to you, then you know what I'm talking about, because it's this. It's this constellation of symptoms that nobody has put together before, which is gut something happens to your gut, then suddenly, you're diagnosed as having Ehlers Danlos. And then it's postural orthostatic tachycardia syndrome called pots. So for all those people that have this, and there's actually way more than we realize, that's what I started with this, I was like, Oh, I'm going to do a, I'm going to do the preface, the the sort of general 30,000 foot view of why we have this and then I started thinking, Wait a minute, why is this why are we seeing more of this now? Why are we having more gastrointestinal issues, which conceivably can lead to chronic long term stuff. And then I had a wake up in the middle of the night moment where I went COVID people are recovering from COVID. But then they're having chronic issues. And it's really all over the map. Now, cardiac issues, pulmonary issues, some some nerve issues, are we going to end up with a whole new wave of almost post Lyme, chronic infection type things that the immune system is turned on? So then that got me thinking, I'm like, Oh my gosh, we got to figure out this whole motility deal. And during this really busy time, I've got all these people and then I got a article was sent to me by the Journal of American Medical Association, this month, September 2020, that signs of depression have tripled in the US since COVID 19 pandemic So 28% of the people surveyed had at least one symptom of depression, you compare that to 8.5% pre pandemic. So it's not just the number, but the severity of depression is increasing tremendously also. And there's actually a significant number of people that have been diagnosed with serious depression. When you fall into that category, you start really worrying about suicide, you start really worrying about breakthrough of other problems. And it usually requires a ton of treatment and different things to try and get this under wraps. So there's very little research going on right now discussing this. So we've got this COVID problem, even if you don't get COVID. So if you get COVID, it's possible, you have to worry about a long term consequence. We know it can infect the gut. And then even if you don't, we're seeing the next wave of impending pandemic of depression that we're going to have to deal with. SoEric Rieger 6:00 No joke. I was just going to add that the I guess the the syndromes that you're describing Ehlers Danlos, and POTs, etc. It is reminiscent to the time when you were addressing IBS and bloating, okay, because those were somewhat seen as throwaway trashcan diagnoses. And that's really kind of stealing a lot from you. That's what people felt they're like, well, I don't know, it's IBS, I don't know. It almost feels like it, we're we're now sustaining a wave of POTs and Ehlers. And we're seeing these people come through and they don't really know who they can turn to. And little bit by little bit, it seems like maybe we're making a little bit of headway. So drawing this connection really pulls me in, and others who may actually have happened to suffer from this, or who have witnessed family members suffer from this kind of stuff, because there has to be a way out. And there's usually a cause and just kicking it under the rug and pretending like it's not there is not really going to work. And if we know that COVID is setting us up to experience syndromes similar to this, then more than likely, we can walk backwards and figure out what was it that COVID did to put these things in motion? And what can we do about it? If we become infected to hopefully either curve it or not experience it all together?Ken Brown 7:23 Well, I think one of the biggest things is that if you are in a situation, you cannot have a healthy immune system without a healthy gut. So what I'm saying is that we do have evidence now that when you have a something that affects your gastrointestinal system system, like an h2 receptor, where spike protein can bind to it, and then that's where the, the whole disease starts, that could lead to a domino effect of more chronic problems. And so I'm sitting, I'm just like, wow, okay, this is daunting, my practice is full, we're getting all these people showing up with these, I don't, I can't give them a good answer. On the whole, you had got problems. Now you've got these other long term issues you have to deal with, and this JAMA article comes out. And so this is where I start going down some balls, like man, I really want to be able to help, like, what is this connection, it says there. And then I started looking down this and I was like, wait a minute, let's look at this. Depression essentially is a form of reaction to some sort of stress. Stress, we know causes a sympathetic response in the body, right? We understand that a fight or flight response is the sympathetic response that affects intestinal motility. And we know through all of our other podcasts that we've done, and and other people and guests that there's a tremendous brain gut access. So as your co-host of the gut check project, co COVID, files number 11. I'm at least gonna try and do my part, which is if all this is going on, let's at least protect the gut. And we know that if you were to change the motility, you can develop cebo then you can get leaky gut, and then you can develop these other problems. So I was like, Okay, wait a minute. Now we're seeing that these covered people are having heart issues, brain issues, there's all different kinds of things. I'm like, I can't just get on there and say, well, we got to protect the gut. So I found an article published this month, and I went, Oh, this is what this episode is going to be about. It's going to be about give your neighbor and Atrantil and a hug. Give your neighbor just a little bit of powerful nature's polyphenols and a hug, huh? Yeah. Kudos to Chris Kresser. Because he mentioned this study, in which he went Oh, did you see that thing? So that means like, this study just came out like last week and I was like, Man that stays on top of it. Yeah, a recent study. This is where we're gonna end up. And this is why giving somebody a hug could be very important for your gastrointestinal health. Okay, this is what's gonna be about it given to you in a hug. Okay, so a recent study with rats looked at gastrointestinal motility in the setting of stress. So what these researchers did is they showed that when rats are exposed to acute or moderate amounts of stress is that they were able to show that the rats developed gastroparesis, they did not go into why gastroparesis is slowing of the stomach. I'll explain to my patients that when you go through amount of stress, the sympathetic nervous system slows your intestines down. And were to develop bacterial overgrowth, you have a reflex from your small bowel to your stomach, that slows it down. I get all these people diagnosed as gastroparesis. And when we fix their cebo, the gastroparesis goes away. So these guys were saying, okay, we know that these rats when we expose them to stress, they develop gastroparesis, but we don't really have a way to help them. So then one of them, I really like to see how they decided on this one particular thing, then they decided to check something that has not actually ever been reported before. Someone was that somebody had the wherewithal to say, let's check the oxytocin level. You familiar with oxytocin?Eric Rieger 11:24 Yeah, I am familiar with oxytocin and, and or pitocin. oxytocin, I think is the endogenous form of pitocin. Correct?Ken Brown 11:33 Correct. Yeah, it's also known as the hormone that mostly is associated with pregnancy and giving birth. Right, the pitocin part of it, you as a crna. You, you know, you do the epidural and somebody and then you start the pitocin, drip and it and there's lots of contractions,Eric Rieger 11:49 causes uterine contraction, you get the baby If someone's been induced, and that's what we're doing is we're giving them that hit or pitocin through their IV.Ken Brown 11:59 Yeah. And so the way that I learned about oxytocin was mostly through my gynecologic rotations, where you're looking at stuff like this. Well, as it turns out, it's a really cool little neuropeptide slash hormone, you made it dead and just have one use that we isolated for our own convenience doesn't just have the one use and then everybody thinks about it. It's been, it's been labeled as the love hormone, the cuddle hormone. It's what helps moms develop their lactation when the baby cries, it's an oxytocin response, all this other really cool stuff. These guys said, hey, what if we got their oxytocin up higher? conceivably, what if the stress decreased their oxytocin raise their vasopressin. And maybe that's why they're having GI issues. Nobody's ever put the link together before where it's like, Look, we just say that, oh, when you're under stress, you're you have gut issues. How, hence the vole hole. So what they're able to show is that these rats with higher levels of oxytocin recovered from the stress and improved gastric motility. their guts recovered when they can raise their oxytocin level. Okay. And then they took these knockout rats and what knockout rats and mice are is that they genetically raise one that is incapable of producing something that they want. So then they raise these rats that were incapable of producing oxytocin, and their gastric motility and their GI tract was horrible. So their data showed that oxytocin directly influences the neural pathway of the stress response. Why is that relevant? Because when we have Angie on and we do our motility, deep dive, maybe a couple different podcasts, and Kresser agreed with me on this one, it all comes down to motility, we have to fix the motility. And this is a particular it's known as a neuropeptide. A lot of people refer to it as a hormone that actually affects the neural motility. Eric Rieger 13:59 RightKen Brown 13:59 And I went, Oh my gosh, I have not heard of this before. So now what we're talking about is oxytocin as a stress adaption that could actually help motility. So rather than just immediately build a cuddle room in my clinic, where patients come in and they get rain and Amber and Andy and my all my other staff will rotate cuddling with patients to improve their oxytocin level. I thought I'd look into the science a little bit more before I just jump into that. And then I it got me thinking with not only is COVID creating all this depression is it is some of the problem because we're isolating ourselves. I mean, I still want I mean, I still don't like the zoom way that we're doing this, but at least we have some interaction but is it conceivable that one of the reasons why we're having so much depression so many of these other issues that are we ignoring our oxytocin?Eric Rieger 14:58 Hey, you know, I had to quick things one is quick. And that is, I think that now we've established especially with the with the mice or the rats, that oxytocin is not a gender specific marker or a hormone, right? So males and females are going to benefit from this. But a side note long, long ago, I was watching a special and they were talking about some of the side effects that happen to people who happen to be imprisoned, and who were put like into isolation, for whatever reason, you know, down in the hole. And one of the early issues that occurs with them is GI distress. So I kind of feel like, maybe we're going, I mean, beyond the depression beyond the the the things that could just simply drive someone crazy in their own mind by being isolated. A lot of it was just simply inability to have normal functioning GI tract. SoKen Brown 15:56 anyway. And so let's, let's just keep on that for a second. You have stress, you are able to muscle through some of your gastrointestinal issues. Instead, just have to have to keep the stiff upper lip and keep moving. What you don't realize is that if you're not taking care of your gastrointestinal health, then this could lead to a cascade of other inflammatory things. So how do you improve the inflammatory aspect of everything? That's the really, that's the really interesting thing. Now we have talked improving your immune system by mitigating your inflammatory response using polyphenols. We've talked about improving your NRF two pathway which decreases the inflammatory response. So now I'm going to give you the trifecta of let's go down some vole holes and talk oxytocin. And why do I save vole holes? Because I found this incredible scientists. She's a neurobiologist named Sue Carter. And she's internationally recognized as this behavioral neuro endocrinology PhD. She is the director of the Kinsey Institute, which looks at this and all her work has focused on oxytocin. And she found the what was presumed to be the only mammal that had a monogamous relationship, the prairie vole. So when I say I went down vole holes all the research on oxytocin has actually been done on Prairie voles by this badass scientist named Sue Carter. Yeah, and her work is really cool, because when you read some of this, she studied oxytocin and voles. And the reason why is because they were they were presumed to be the most social mammal and monogamous and they really don't care about their environment. So you can take two moles that love each other, and put them anywhere, and there'll be just as happy because as long as they're socializing, they're, they're super cool. And her first discovery was, voles are not monogamous. In fact, female voles will actually go and mate with a random male vole, and then fight with them afterwards to kick them out to basically come back and be with her lifelong mate. So they have lifelong mates. But the vole will actually go out. And she explained that this is probably it's not like it's a super what's the term for when somebody sleeps around a whole lot? And but the appropriate term is going promiscuous. Eric Rieger 18:34 Thank you for rescuing. Yeah. None of which we're going to be appropriate for today. But yeah, good save.Ken Brown 18:43 So it wasn't that these that these female voles were promiscuous, it's that there's a genetic reason for doing this, that if you can have a genetic pooling, where you have more genes, but it's the family rearing aspect, and so what she was able to show is that it doesn't have to be the original Mother/Father, as long as there's a family unit or some sort of unit. And then, you know, she references a lot of psychological studies in humans, which this has been shown multiple times that, you know, this is where it's at. So the vole has a very similar oxytocin response to humans. So it's the perfect mammal to actually study. And at this point, that's why I'm going down boltholes. Now we should probably define really, what oxytocin is on a little more scientific level. oxytocin, it's an evolutionarily ancient neuro modulator, and hormone produced in the hypothalamus where it's pumped directly into the brain and into your circulation. So very complex way to say this thing has been around since the dawn of time, to help us adapt to our environment. And in fact, oxytocin, which is the love hormone is known as the cuddle hormone. It's associated with childbirth and women. But now we realize it's in everybody. When it goes up, that really means that you're in a time of abundance, that means that you're in a time, this is a time to love, this is a time to do things. And when that's up, it actually does all different kinds of things. And we'll get into that in a second. But one thing it definitely does is it improves your immune system by decreasing inflammatory markers, very similar to how the NRF two pathway functions. When there's types of stress, All right, now, your oxytocin goes down, your vasopressin goes up, and you send signals that you're under duress. Does that make sense?Eric Rieger 20:46 It does. And so basically, if you it just sounds to me, like if you're under a lot of stress, it's hard to love. And if you aren't receiving love, you're probably going to find yourself in a lot of stress.Ken Brown 20:59 Yes, so here is the thing that nobody's talking about, we've got a massive amount of depression going on, because of COVID. And then we're saying everybody stay away from each other. Yeah. When the reality is what we're going to do at the end of this podcast is talk about how we can increase our oxytocin levels. But just to show how important it is, what was she was able to do just a few of the things it enhanced memory production. It has been shown to increase muscle mass. So it has been shown to help heal wounds quicker. So they can show when your oxytocin levels up. You have less serious infections, you actually can learn things better. You can develop more muscle, it's like kind of a, it's one of those like, that does too much. Well, it's that important. It's one of these homeostasis type hormones. oxytocin vasopressin, she was talking about all different kinds of studies that perhaps one of the reasons why there's a cycle of teen pregnancy in certain lower socio economic areas. Could be that when a mother is stressed, she sends a signal to the baby that's in her. Oh, hey, we got hard times. Yeah, baby. Down regulates its ability to produce oxytocin. Oh, my. So it comes out. guns blazing, not ready to cuddle? Yeah, baby has been sent a signal that says you are being born into hard times. And when that happens, then you can end up with a sequence of events. And it's just tip of the iceberg about where she was going with it. And she showed it with these prairie voles, she had certain moms that were under stress, well, then the baby would have lower oxytocin levels throughout its life. They go so far. Yeah, it's really wild stuff. Super, super wild. Because I'd never really thought about oxytocin before. I've always thought of as a pregnancy thing. And now I'm like, whoa, wait a minute. So what it helps you do is it helps you adapt to a changing environment. I was thinking of a Time Suck. With what? Dan Cummins, Dan Cummins. And I just had to laugh about it. Because he he almost describes this when he was doing the Genghis Khan, he's just like, Yeah, can you imagine being born in this is a kind of like, you're born into this horrible world, and you're just about money. And I'm like, oh, that oxytocin was really low in poor Genghis. Yeah. And yeah,Eric Rieger 23:29 it really, really was.Ken Brown 23:31 And so a lot of the oxytocin levels in a community can be manipulated by the strength of the community, and learning from others. So part of what makes the oxytocin go up a little bit, is the reward aspect also. So when you learn from somebody, and you don't have to fail a bunch of times your oxytocin goes higher. So each generation, if done right, should have slightly higher ability to have the oxytocin because you're learning from the next group in front of you. And then it it's, it's a safety thing, the more control you have, the more abundance you have the higher abundance, meaning you're not fighting for your life, not Lamborghini, whatever, I'm pretty sure that, you know,Eric Rieger 24:20 in a weird anecdotal way, if you think about just growing up and being in a classroom, it seemed like that, in certain subjects, you would have friends that were just more adapt and and better at listening and getting instruction. And so as a lesson progressed, they didn't seem to stress about subject matter. So their ability to relax and learn and take in information. They had a comfort zone with that. So they may have had some amounts of oxytocin being released, which allowed them to take up the material and then they didn't stress as the material is reintroduced. They were tested on I mean, it's, it's a cycle, right? So it's probably there's probably a pattern there, too. Where we can, we can help our young kids and children, etc, by learning how to get comfortable learning, learn how to learn.Ken Brown 25:07 Yeah, absolutely. Now the good news, Eric, you don't have to worry about this at all, because as we've discussed in multiple different ways, Big Pharma is super excited to be involved in the oxytocin rush here.Eric Rieger 25:20 Yeah, I'm sure that they've, they've got our best interest at every dollar.Ken Brown 25:24 So they've got multiple animal studies showing that you can kind of manipulate the oxytocin in an animal. They've got nasal sprays in Europe with just straight oxytocin, we've got this synthetic one pitocin. Well, she's also got a ton of ton of work about how that will never work. Now, it will never work. You cannot play Mother Nature in somebody's body with something so intrinsic and delicate and complicated. So unfortunately, at least in human studies, when they have tried to do this and develop a drug where you just take a shot of oxytocin, and your immune system improves and everything, your body, surprise, surprise, starts to down regulate some of the oxytocin receptors up regulate the vasopressin receptors, because it goes this is weird. This is something's odd, and so then the body automatically offsets it. So then when you stop, you've got all this vasopressin, which is your fight or flight, workplace and when you beganEric Rieger 26:21 gonna be stressed out to the hilt, it's it's it's no different than when someone over for a long period of time consumes steroids, and then they don't produce their endogenous steroids anymore. I mean, that the adrenal fatigue or they shrivel up, they don't do anything. So it's a it's a real problem.Ken Brown 26:38 Yeah. So here we are, in this pandemic, the vole hole was I'm I'm worried about chronic conditions, and dysautonomia, and gi issues, which then led to finding the study on the rats, which then used oxytocin to look at. And so here we are, in this pandemic, depression is super high, we're socially isolated. We know that when we're stressed, we're going to have lower levels of oxytocin. It's that seesaw. If you're really stressed out, you're basically telling the vasopressin to go up and oxytocin goes down. Easier said than done, right? Don't be stressed, you'll be fine. So we know that right now everybody's stressed. So your oxytocin is lower, this can lead to my perspective, the GI tract will be affected. So a neurologist will tell you what it will do in the brain. a cardiologist will tell you what it will do in the heart. But we do know that oxytocin affects gi motility. Gi motility, in my opinion, is the underlying reason why all these chronic conditions are actually developing. So you're gonna have poor intestinal motility, you feel bad, which actually leads you to want to be more socially isolated. So a lot of the stuff when people are like, man, I just, I'm unhappy. I'm depressed, but I don't want to be around anybody. Yeah, give you a neuropeptide reason why that is your oxytocin is low. Your vasopressin is saying this is not the time to be cuddling. You know, we are flight thing going on. Right?Eric Rieger 28:10 It is getting to these, there are many, many examples it seems in life where we you can easily fall into these catch 22's, where you're, yeah, you're heading this one way. But for you to recover, you almost have to break the bounds and force yourself to do something that will allow you to get better. Otherwise, you're just going to stay unfortunately, in this cycle.Ken Brown 28:31 Yeah. So if you're listening to this, and you do have a little, any type of depression, any type of anxiety, we need to get your oxytocin up. If you have irritable bowel, if you've got cebo. If you've got any other gastrointestinal issues, we need to get your oxytocin up. Oh, if there's a slight possibility that you could be exposed to a virus. You need your oxytocin up so that your immune system reacts appropriately. Now let's get to oxytocin and the immune system is that oxytocin does exactly what our NRF two pathway does. They all work together, polyphenols, decrease interleukin six, which helps mediate your response. Yeah, it turns out oxytocin mediates the body's response so that you don't overreact. It's all about the thing that we talked about the endocannabinoid system, it's about being in balance. So oxytocin actually helps your immune system, which could be one of the reasons we said it during the NRF two, podcast but you can almost say, well, maybe a little bit of oxytocin's taking place because when you're NRF two is down. That means that you have higher inflammation. Once you have higher inflammation, that means your oxytocin will go down. So it's that you're exactly right. You got to break a cycle here.Eric Rieger 29:50 Yeah, you got to you've got to go against intuitively what's Unfortunately, the pattern that feels like that, that you're on the path that you're on, right. You ever think about it? When you've got your friend and you're, you're growing up and your friend, he just broke up with his girlfriend, or if you're a girl, it's your girlfriend, or boyfriend, they're really sad. They don't know what they want to do and feeling really down, but you convince them to come and hang out with the friends, etc. And almost every single time, by the end of the evening or the outing, whatever it is, that particular person is ecstatic that they were, they're surrounded by people that cared about them, they loved them. It sounds like it's a lot of this community that you're describing, because it helped them get through something, right.Ken Brown 30:34 So this is the crazy thing. So I've talked to patients that been going through a lot, they start going through depression, they start gaining weight. They're like, I don't know, I'm even now I don't want to be around anybody I've put on, you know, 40 pounds, since it's COVID. Oh, I hate to break this to you. You're gonna put on weight if your oxytocin is low. Why? Because your vasopressin goes up, which is your fight or flight, which is your cortisol. So every time that you said, Well, I'll start mingling, once I lose weight. So as a weight loss product, we're going to tell you how to get your oxytocin up. In fact, I was talking to a patient today. Wonderful, just love to see people when they round a corner, and they're just really happy. Yeah, a patient of mine I've had for 17 years, and looks phenomenal. Did his COVID hair looks great. And it's his disease, underlying disease that he sees me for is under total control. And I start finding out, got remarried, has a new social circle. They have a they have a process where they, every Sunday, they have dinner together every whatever. And I went that is it right there. Because in every single medical study, listen to this one more time in every single medical study, a support system and social interaction will outperform drugs and diet. Now, there's a lot of people that would go No, no, no, no, no, you're insane. But if you look across the board, and you start really realizing that and you start teasing out some of these factors, actually people that do have a support system, and it was always theorized, oh, well, they have a support system, because their family members help them make sure they stay on their drugs. Oh, they have a support system, because they've got this and that could be oxytocin. Yeah, it could be this one thing that nobody's talking about?Eric Rieger 32:29 Yeah, definitely. No, I agree. I mean, just take an inventory of the people that you know, best. And not I mean, probably not every time someone will have a different example. But usually, your happiest friends, your happiest family members are those who are in touch surrounded by not only support, but they give support and they receive it. And I'm just thinking of just several people. Yeah, that's who they are.Ken Brown 32:56 So the oxytocin's every night, this Volvo was really big this that Sue Carter has dedicated her whole career to it. And the science behind it is all her data. And it's really big. It's the first time I started looking into it. But of course, I got to do what we try and do, which is bridge some bridge some gaps. So we will try and give you some tips on how to increase your oxytocin naturally. But I also want to look at a couple other things, we always seem to find that when you start looking at Mother Nature, secret weapon polyphenols, is there any data with this? So I really struggled to find a direct one to one, but there was a couple small studies looking at breast breast milk production, through the elevation of oxytocin. And this particular study showed that the combination of two different polyphenols, one of them being reservatrol, increased milk production through oxytocin release. So that was one of the only times that actually found that polyphenols directly increased oxytocin. And they were looking at it to try and stimulate more milk production. Okay, and then there was one randomized trial on delivery. And they were looking at, interestingly enough deal extract and its effect on oxytocin. And they showed that it actually showed a randomized trial where when you added the dill extract, which is a polyphenol, then it improved the delivery process. So smooth muscle contract, contractility, etc. And then I found this one, which is a little bit interesting, it makes a little bit more sense. Because we know this, we say this all the time. This article comes from the journal of probiotics and health, microbes, oxytocin, and healthful longevity. In this particular tastes, they showed how our microbiome interacts and through decreasing what they believe are different inflammatory mediators. We know that Do it has a direct effect through the vagal nerve directly on the hypothalamus to oxytocin levels. So, all of this is kind of extrapolating Dr. Carter does most of her work on these voles and amazing on family units and stuff, that one right there that nobody's really looking into as do these polyphenols also have an effect on the oxytocin level couple small studies, but we do know that these polyphenols increase the microbial diversity. So the reason why I said take out Ron teal and give somebody a hug, is because we know that the polyphenols, stable large molecular polyphenols, increase the microbial diversity. And we know when you have that, that a lot of other beneficial things happen. These guys in this paper showed a direct vagal mediated oxytocin response, meaning the vagus nerve, the great highway is a motility thing, we keep circling back to the same things. So other than make sure that you do the usual stuff that was talking about get some good sleep. I believe that polyphenols probably increase x increase oxytocin levels. And we know that at least in a couple small studies, that you can increase oxytocin through several different smaller polyphenols. And then this final one was that if your microbiome is diverse, you will produce more oxy tosun. That's really cool. That's really nice. Here's what's the best. It's called the cuddle hormone for a reason.Eric Rieger 36:39 Now, hugsKen Brown 36:40 let's quit being so sciency get our accion. Oh, no, no, don't I actually googled that. And I started to type in how to increase oxy. And it was like cotton levels were to get. Oh, no, no, no, no, no, no, no,Eric Rieger 36:57 no. Yeah, yeah, you don't you don't want that of your teenager how to increase your oxy acne wipes, you know, so.Ken Brown 37:07 But it's kind of interesting, because you because you, you look at these little voles, and you realize it's probably, the more the more that you love and share, the more that you open up, the more that you allow your body to increase the oxytocin receptors, so that they can be saturated more, and you're getting away from that sympathetic response. So what's your favorite way to raise your oxytocin?Eric Rieger 37:30 Ah, man, I can tell you right now a hug from a from wife and or family member friend. And any of that it sounds to me would be the most fun way. And then favorite way to to raise my own oxytocin. Alright,Ken Brown 37:46 so there's lots of ways to raise your oxytocin. And this is a this is a quiz for you. Eric Rieger 37:53 Oh, no.Ken Brown 37:54 Yeah. So we know that exercise raises oxytocin. Okay. We know that listening with your eyes, meaning real eye contact with somebody can increase your oxytocin being intimate with someone will increase your oxytocin. Okay. And basically, the whole cuddle aspect is there. So if you can incorporate all those different things, is there one particular act that would really knock the socks out of the oxytocin ballpark? If you could exercise be intimate? be close with somebody share a moment? Oh, oh.Eric Rieger 38:37 Probably, man. It's rolling dice here. All those are things that hopefully everyone's getting the opportunity to do daily. I would say getting close to somebody would be the one that raises the most, maybeKen Brown 38:50 you and I think differently.Eric Rieger 38:55 I guess you're about to break out a barbell not really sure.Ken Brown 38:57 No. Eric Rieger 38:58 Okay.Ken Brown 38:59 Exercise, being intimate. Being close. Having human contact. sex. Sex is amazing for raising oxytocin. SoEric Rieger 39:08 Oh, yeah, no, I mean, um, maybe, maybe. You're what? Maybe I was getting too g rated.Ken Brown 39:17 I'm just saying that, that do not underestimate the power that that being intimate with a close partner. A company accomplishes all those things at the same time.Eric Rieger 39:26 Yeah, yeah. Yeah. Oh, I get it.Ken Brown 39:29 You say another way. Another way to increase oxytocin is to have an orgasm. So okay, having but you know, but they've also shown that by having a close intimate partner, the oxytocin goes up much higher. Your body knows you can't fake it, you know? Sure. It's so that's so alright. So, exercise, social gatherings. Listen with your eyes, have sex. Oh, give a gift. being generous will actually bump your oxytocinEric Rieger 40:00 Interesting now that that actually is is is awesome. So sorry but I guess the the noble rewards in life tend to tend to be associated with doing good deeds right? Because you share love with someone and that's so good deed you're letting them know that you care about them you you know you foster your relationships with with your friends then that that's that's a good deed you're helping them out. So yeah, I mean to me it makes sense. Yeah, it's funny you didn't you didn't mention that, that using businesses as a reason to screw somebody over increases oxytocin. You didn't mention that theft or isolation increases oxytocin, it's all of the it's all of the opposite things that we all say that we want to do for Yeah,Ken Brown 40:48 so next time you're in traffic and somebody kind of a jerk and cuts you off. Don't just sit there and get super upset. Just go, oh, that person's oxytocin is low. They're not doing the things to cultivate their oxytocin levels.Eric Rieger 41:01 Yeah, put your car in park and then look at them and listen with your eyes.Ken Brown 41:04 Yeah, listen with your eyes.Eric Rieger 41:10 Maybe not. That may not be the right.Ken Brown 41:12 Yeah, maybe that's not the right way. You could also I had to laugh. So a deal I was I was talking to her deal yesterday, my, my, my wonderful Scheduler. And I was trying to describe what I want to talk about today. And I was like, hey, do you know that like, heading a dog has been shown to increase oxytocin levels? And what about a cat? I have a cat and I was like, No, no, never.Eric Rieger 41:35 Not a cat.Ken Brown 41:36 No. Only dogs. I think cats also i'm not sure the study was done on dogs. So it just got me thinking I'm like, Okay, look, we're in this COVID environment. There's so many things against us. And yet we have a few things under our control. So listening to music, playing music can also raise that but waking up every day and saying, Okay, I'm going to try and figure out how to raise my oxytocin, which means that I'm going to try engage with somebody a little bit more, which means that I'm gonna try and take care of myself a little bit more if I'm going to be easier on myself. Because when you're hard on yourself, you raise your vasopressin level, which decreases your oxytocin. So give yourself a break. If anything, do it for your intestinal motility. Say, I'm, I'm going to make a concerted effort to which is why I said at the very beginning of the show, I'm trying to call mom more because we need to keep each other's oxytocin up, but you know, she lives alone. And I want to make sure that, you know, she's able to keep that oxytocin up. So this is a this is the vole hole called How to Increase your oxytocin kind of out of left field, I started down a motility path and we're going to come full circle because once we start really hitting that motility, this may become standard of care for a gastroenterologist to help patients.Eric Rieger 42:56 I mean, kind of a cool intersection now, I mean, we do a lot of things whenever people come through and use everything from diet to behavior to recommend exercise, why not just start saying be sure that you give a hug to your family members everyday or a close friend every day? Yeah,Ken Brown 43:13 and that's the problem is that we're in COVID. So that was one of my theories, that the isolation could be controlled Yeah, massive increase in depression, no doubt.Eric Rieger 43:25 No doubt at all.Ken Brown 43:27 got me thinking. So I would like to check oxytocin levels on you guys that do jujitsu because there's there's lots of hard cuddling going on during jujitsu if you call it cuddling, choking someone, for instance, which I think has kind of a has an oxytocin bump, but also a vasopressin fight or flight going on. I'm wondering if jujitsu people I'd need to check with Ricardo Abreu and see we just need to monitor his oxytocin levels as he's as he's smashing peopleEric Rieger 44:04 as he is if he uses the same tone as he aggressively went after you as a polyp. I don't know that I want to help him raise his oxytocin levels.Ken Brown 44:14 Yeah, that's true. Maybe it's Yeah, maybe it's low. So um, you know, we we keep coming back to the same thing we keep coming back to intestinal health is the root cause of all health. And now we're finding these different things that are really subtle that we can do in a holistic approach. You can increase your NRF two levels by doing certain things, you can increase your oxytocin. And all of this will play into the immune mediated aspect. I start thinking of people that are diagnosed with a pretty serious, you know, chronic situation, and it's depressing and it's sad and they're maybe in pain and all that just keeps lowering that oxytocin. If you could just get that back up. Maybe it'll break the cycle and you could start on a road to recovery.Eric Rieger 45:01 Yeah, I don't know, either. But it would make sense. I mean, maybe having people isolated in a hospital, for instance, especially during COVID where we're not allowing people in there is actually stunting their ability to overcome disease. I mean, think about that when how many people and stories have we heard of firsthand so and so had to go in for surgery, we don't really know how they're doing that but they call and said that they're just going out of their mind you're stuck there and it's taking longer for them to to be released from the hospital. I mean, it could have a profound effect as we're trying to stem the the the spread of the virus, but at the same time, we're not allowing other people to heal. You know, at the rate that they should, I don't know, it's it's pandemics present lots and lots of problems that areKen Brown 45:49 not been trying to figure out there. There used to be there was a gastroenterologist in my community that when he retired, he, he loved dogs. And so he had like these show dogs, he would bring them as animals and just allow patients to pet the dogs. Yeah. And now I look back, I'm like, wow, I'm like, let's take it up a notch. I mean, if we know that these prairie voles really raise their artsy tosun levels, then maybe we should have some variables and just like let them bite people and just inject the oxytocin and I'm gonna, I'm gonna have to talk to Dr. Carter about that one. I'm not really sure that's gonna work. Yeah, you just made oxytocin a venom. So the hard part is you got to get the prairie voles super happy and comfortable, then you gotta piss it off enough to bite yourEric Rieger 46:35 budget. Yeah, yeah, that's exactly right. Yeah, I don't I don't think that's the avenue but that's okay.Ken Brown 46:41 And I do believe that they have the full science on the half life of it also. So it's not like it happens. And then unlike the NRF, two pathway that stays elevated for some time, the oxytocin is much like an Endocannabinoid like, like an amide. It comes out and it works and it comes back. And it just is as needed when it comes. So what I'm saying is you got to get that parallel the prairie vole to bite you really quick, because I think the half life is only like 30 minutes. It's gonna be hard.Eric Rieger 47:10 Yeah, I it's, it's going to be hard to, to prove to even see your ideas worth anything. You know, I don't know.Ken Brown 47:19 What we're doing here laughing a little bit that's raising our oxytocin also. So even if just at least make some jokes about prairie voles, and maybe that'll raise yourEric Rieger 47:28 venomous prairie voles. Yeah. Yeah. There's a lot of jokes in there. But yeah, that would be weird and strange. But, yeah, maybe you'll get happy out of it, too.Ken Brown 47:40 So that's the vole hole I went down. So can you summarize all this for me really quick, because I realized I was kind of all over the map on this one. But that's not I think it allEric Rieger 47:48 over the map at all. I mean, he just gave more reinforcing evidence that the fact is, is that can paint the reason why we don't like being isolated is because we're not supposed to be but one of the many reasons that a pandemic really stinks and, and not being able to see your friends why people are longing to get back and seeing their families because we're meant to be social. So when it's safe, and you can figure it out, by all means be as social as possible. Find the people that you care about the most embrace them, tell them that you hug them, it's it's not just enough to see them on camera, it's not just enough to, to just hear them on the phone. You You really want to go embrace and hug and let somebody else know. And then I like the other one, too, listening. Look at someone hear them. That's one of the most empathetic things that you can do for someone is just be quiet, don't talk over them. And let them voice whatever is on their mind, happy, sad or indifferent. And it's actually going to work to your benefit to do it. kind of crazy.Ken Brown 48:53 Are you actually talking about oxytocin or the fact that I do interrupt all the time, and this is just a polite way to tell me to just listen,Eric Rieger 48:59 so you didn't do it? Right. You're supposed to sit there and just keep staring in one of these days. I'm just kidding. Yeah, now? I do. I do think it's kind of cool. There's a lot of lessons in there if you just want to be happy and healthy. Scott Golden Rule stuff, treat people as you want to be treated. You want to be hugged, give you you need a little help do some charity. Yeah, it's it's, it will all work to your benefit. Well,Ken Brown 49:19 we know that giving a gift works. We know that improving your microbiome works. So your sign behind you your bloating relief, it's what we do. I'll try until what you should do is buy a bunch of Tron to and give it away as a gift and hug that person. And then you're going to bump your oxytocin way up and you're going to help that person bump their oxytocin.Eric Rieger 49:42 I don't see how you can go wrong with that. You can'tKen Brown 49:44 go wrong with that. Give Atrantil and give a hug. That's awesome.Eric Rieger 49:50 Yeah, that's a much better summary summary than what I was working towards.Ken Brown 49:54 Now, I didn't have time to look into how the endocannabinoid system plays with oxytocin but you know, that's tied And also, because this is all this just shows how complex humans are tied in, we'll eventually get to how improving your endocannabinoid system. But it seems like everything that improves everything that I just said for oxytocin actually decreases the sympathetic response, we get back to the same thing over and over and over again, inflammation creates disease, inflammation does is the root cause of the disease process. When you have inflammation, your NRF two pathway goes down and your oxytocin goes down. So you at least need to take the reins, stop some of the inflammation through a proper diet, eating polyphenols, taking a proper CBD to improve your endocannabinoid system, and then maybe your body will adjust by rising these other systems, these other molecular processes.Eric Rieger 50:49 Yeah, oxytocin, ultimately, not just a pregnancy hormone or peptide. It's quite important for us throughout our entire existence. So unfortunately, I mean, we mostly in the medical community, at least allopathic Lee only talk about oxytocin as it applies to the maternity ward. So way more important than that,Ken Brown 51:10 it's way more important to that. And you know, that we really can't have animals in the endoscopy suite. But I'm gonna ask a small favor since your hair is really grown out. Okay. I think we should let stressed out patients just pet your head as they're waiting to go back for their colonoscopy.Eric Rieger 51:24 Yeah, day after hand sanitizer, I guess. Again,Ken Brown 51:29 or somebody that's super stressed out here. Would you mind letting them pay?Eric Rieger 51:34 As long as I don't have to lay down and kick my leg several times across?Ken Brown 51:40 Well, that's awesome. Yeah. oxytocin, we just keep throwing curveballs at you.Eric Rieger 51:44 Yeah, well, hey, listen. For the listeners out there. I think that we keep hitting hinting at it but pretty soon we need to dedicate a series or a show to the vagus nerve and we have actively been looking and talking to a few different people will have a vagal nerve expert on here pretty soon and I'm excited about it. It really ties into exactly what Ken is talking about with oxytocin and everything that we can do to help out our parasympathetic nervous system which is the relax the love the feel the the rest and digest mode, I guess, if you will, for our bodies. Yes, it's quite a bit I thinkKen Brown 52:26 we're gonna end up so we're gonna let Angie run point on this because she has done so much research on the dysautonomia, which is the the dysregulation of your neurologic processes in relation to different organ systems. And that's the whole Potts, maules, cebo relation, Ehlers Danlos, and all these other things. So we'd start with that. But I think if we can figure out the motility aspect, it helps so many people, it's all it's all connected. And it's an it's almost like you can't just do the one thing, you can't just, it's like you got to do it all. You got to get socialized, and you got to feel good about yourself, you got to be happy or try to be happy. Anyway, that works for you meditate, everything start working on that, though, you will start losing weight, then we can start the healing the gut it all, it's all coming together. And if we could develop some sort of really nice rationale why people are having issues they are. And I think that alone helps people to start on the road to recovery. Because just being told it's all in your head is doesn't cut it.Eric Rieger 53:43 No, not at all. Not at all. Well, Ken, I think that the instructions are hopefully clear. Go hug somebody. Go hug somebody.Ken Brown 53:53 Yeah, so as always, this is a medical show, but I'm not giving medical advice. I'm a medical doctor Eric delivers anesthesia for a living. But just speak with your doctor. If we said anything that looks like you need to question it, but we're in social isolation. So don't randomly go up and hug people. But you can certainly you can certainly improve your oxytocin by sharing this episode, possibly liking this episode that will increase your oxytocin level.Eric Rieger 54:24 Yeah, absolutely. Well, I can share I can share. This is obviously code file installation number 11. I'm Eric Rieger here with the awesome co host, Dr. Kenneth Brown. Thank you all for the continued email and shares that we get. I don't know. I'm amazed every single week that we have more and more people who write in and say, Hello, thanks for doing the show. So as long as we get those will, will keep meeting up and hopefully we're we're covering topics that they interest youKen Brown 54:53 know, I want to send it when we send this email out to let people know that we've published this I'm going to send a virtual hug know what virtual hugs Come on back at us just just take just just just take a little video of you just hugging.Eric Rieger 55:04 Oh, yeah, yeah, hugging. Oh and quick shout out to Sheila Unger, she she actually you asked about the family earlier she sent a a free complimentary sample of a Texas Tech face covering out the gauge. That's awesome. Cool. Yeah, awesome.Ken Brown 55:23 So they're right there. She raised her oxytocin level he didEric Rieger 55:26 that was that wasn't a charitable gift. Absolutely. Okay. I think that's gonna do it for this episode. We will see you all next time. Stay safe. Give a hug. Listen to people. And don't forget to like and share and we'll talk to you all soon. Right onTranscribed by https://otter.ai

Gut Check Project #40 with Dr. Tom O'Bryan

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Play Episode Listen Later Sep 3, 2020 81:30

Eric Rieger 0:00 Hello It is now time for the gut check project KBMD health fans and those at the Ken Brown clinic. I'm here with my guest host, Dr. Kenneth Brown. We've got an incredible special guest with us here today Dr. Tom O'Brien joins the show. Like and share of course, Dr. Brown once you take it away and introduce our awesome guests. Ken Brown 0:19 Well, I'm so excited because Dr. Tom, you and I have been running in similar circles. And every time I bump into somebody including different lab companies, including different mindshare people, everybody's like, Hey, you and Dr. Tom need to hang out. I'm like, I keep missing him. I'll go on a summit and he'll be like before me or after me. And then I'm just like, Oh, this is awesome. So we finally got you, wrangled in, you've got so much stuff going on. You're an author, you're a doctor, you obviously do some incredible deep dives. And what I love about you is everything that I've seen you on a webinar on a summit is science backed and that's exactly what we do. So I'm just thrilled I I have no agenda for this. You got a ton of information. If we ended up talking about something that I need to learn about, I'm just going to peel off and say, Wait, explain that. And that's, that's for me. So I'm not trying to question you, but like, sure, where I've read some of your stuff. And it's pretty cool. We're talking the same stuff, fix your brain through your gut, that kind of thing. That's all about us. So, welcome. So excited. Dr. Tom O'Brian 1:18 Thank you. Thank you so much. And I'm thinking a place to start if I may. The Alzheimer's Association came out last year and said one out of three elders dies with Alzheimer's or another dementia. So that means between the three of us, one of us is going down in our brain function, and it ain't gonna be me. Ken Brown 1:42 It's gonna be Eric. It's gonna be Eric.Eric Rieger 1:43 This is unfair.Dr. Tom O'Brian 1:44 I feel like I understand. But that's a reality check. And with a reality check like that, whether we like it or nobody likes to talk about brain function, no one does. You know, we all know someone that had a heart attack and survived. They changed their diet, they started exercising, they lost 25 pounds, they look better than they've looked in years. Most of us know someone diagnosed with cancer that went through the recommended protocols. And they're doing better than they've done in years. No one knows anyone diagnosed with a brain deterioration disease that's doing good. It terrifies us. And so we avoid the topic. So I want to talk about first the reality check that our healthcare system is not quite working the way we want it to and more people are getting sicker, especially if we talk about the brain and kids with autism and the numbers are skyrocketing and all that, but how can we look at our health care if our bodies aren't working the way we want them to right now? What's the big picture view of that? How do I get a big picture and I want to suggest this concept because I have found that this works really well. When I moved from Chicago to Southern California in 2010 I needed a map. How do you get from Chicago to San Diego? You need a map, you know, and I may know how to get to Denver cuz you just get on I 80 in Chicago, it takes you to Denver, right? You know, I may or it actually doesn't, it takes you close and you have to go up and 94. But I don't know how to get to San Diego, you need a map. When your body is not working the way you want it to you need a map. You can't just look for a better form of vitamin C, or what brain nutrient Can I take to help my brain function better? We have to have the map and what is the map in healthcare. The map is understanding at a layman's level, how I got to where I am and if we don't. To understand how we got to where we are right now, we are just like a dog chasing its tail trying to get somewhere else. So the question about brain dysfunction, or the question about auto immunity is, why is the immune system attacking my own tissue? Why is my brain not functioning the way it's supposed to, and you have to do a deep dive. And you don't need to be a geek and know the science because there's lots of information out there now. But we have to be willing to be uncomfortable for a little bit of time in being overwhelmed with knowledge. And we take it just one step at a time. That's why the subtitle of my most recent book, you can fix your brain. The subtitle is just one hour a week to the best memory, productivity and sleep you've ever had. And it's not cutesy subtitle It is the only way to be successful at changing the direction your brains going. Because as you learn more and more about the things that you didn't know, you mean that little bit of mold on my shower curtain there, it secretes spores into the air every time I take a shower, and I'm inhaling those spores and they go right up to my brain. And the number one type of Alzheimer's of the five types is called inhalation Alzheimer's, meaning what you're inhaling is causing the inflammation in your brain killing off brain cells. Yes, change shower curtain, you know, or whatever the trigger is. People don't know what the trigger triggers are. So they don't know what to do and they're hoping for a magic pill. You need the map. How did I get to where I am, so you then can make the corrections over six months to a year that turn your health in a new direction.Eric Rieger 6:00 I agree with that. I think that with where you're where you're beginning here in our discussion, many of the things you listed there, there's a lot to unpack, but many of the things that you listed there are, I think some huge tenants that that we discussed here on the go check project. One of those is that gut brain access, Dr. Brown talks quite a bit about the relationship for brain health and how it begins really with systemic health, which obviously originates in the gut. And then you're talking about issues of, of nerves and obviously the brain is a bundle of nerves but neural health and so what is it specifically that we need to do to protect our bodies from I would assume you're getting to long term inflammation what what the caveats are there that are initiating those inflammatory responses? So is there something that you wanted to kind of peek at there were Ken Brown 6:51 Yeah, so love where you're going with this. I'm um, as a gastroenterologist what I'm seeing is an exponential growth of autoimmune disease, Crohn's all sort of colitis are those celiac disease. Those are the ones that I deal with. And we're seeing this huge exponential growth. What you're describing is one in three people getting Alzheimers, we are seeing that autism is increasing. there's a there's a common theme here. And it's this upward hockey stick that's going on with chronic diseases. I love everywhere you're going and you I'm my bandwidth is only so large, where I have to kind of focus on how do I improve your gut to improve your brain and now you're talking other aspects. I want to get into that, but I want to know more about the guy. I'm a real big fan of how I built this. So I want to know more about the guy, the doctor Tom, how did you end up deciding that you were going to go down this path? I've heard a lot of your lectures so I know that you're super smart. I know you're very well read, but I don't know you. So let's talk about you for a moment. Dr. Tom O'Brian 7:52 Sure, sure. When I began my medical education in chiropractic school, very first week, the very first week I knew absolutely nothing. You know, we're working on a cadaver. I've just seen a dead body for the first time learning how to work with cadavers and genetics classes. There was a sign Dr. Sheldon Deal. Mr. Arizona was coming on campus to give a talk on Wednesday night. My very first week. This was the first week of January 1978. And I thought I'll go listen to this guy, Mr. Arizona bodybuilder, he's going to be a healthy guy. So I go to the talk. He has a color television on a stand in the room and back then color televisions were pretty new. And so to see all those colors, you know, he had the television on but the volume offand he walked over to a desk opened his briefcase to pick out a bar man, an iPhone, walked up to the color Television holding the iPhone like a flashlight you know policeman holds a flashlight up Hi, walks up to the color television with this bar magnet, the picture turns upside down and walks away. It goes right side up and walks towards it goes upside down. walks away it goes. Right? In attic pollution does to your brain and your nervous system. It's called neurological switching. These are people that say right, when they mean left, they write the number three backwards. they they they just are confused. And it was the first evidence in my mind the first introduction to electromagnetic pollution Ken Brown 9:51 1978 he was talking about in 1978. That's crazy.Dr. Tom O'Brian 9:55 Yes, because he he was talking he was talking about batteries in a watch and because they were fairly new, and when you put a battery next year body and this was a watch that it can for sensitive people, not for everyone but for sensitive people. It can be the straw that breaks the camel's back. And it impacts on their neurological organization, and how their their brain and their nervous system functions. Nowadays, we take it for granted Of course, we wear watches with batteries, and we put ear pods and our years we put batteries next to our brain. And, you know, we're using headphones that are remote wireless, so more batteries next to the brain. You know, I'm a strong advocate that we never put a cell phone next to our head. You either use the speaker or you use a corded earphones so that you're not putting especially for children whose skulls are thinner and these electric magnetic waves penetrate through a thinner skull of a child. And now there are so many studies on that. That's why in the book, you can fix your brain. I talked about the pyramid of health. Remember, we're still looking for a map here. How did I get to where I am? So in a pyramid, we think there's three sides to a pyramid. No, there's four. There's also a base. So the base is structure. That's the home of chiropractic and osteopathy, and massage and pillows and orthotics in your shoes and is your car seat tilted back. So you're driving like this all the time. That's, that's structured the base, then there's the biochemistry, the one that we all know about. And that's what we eat and drink the air we breathe. Then there's the spiritual or emotional and then there's the electromagnetic. So whenever you have a health concern, you have to look at all four venues to see, where are the triggers that are contributing to my body not functioning the way it should. So that was my introduction in January of 1978, to healthcare. And from that, I started looking in the literature and I found some children living within a quarter mile of high power tension wires had higher incidences of leukemia. That was 1979. I think I found that first study. And by the early 80s, mid 80s, there are many studies coming out about high power tension wires, and people's health if they live near that. So that validated for me, that for some people, electromagnetic pollution was a problem. Not for everybody, but for some people. And the same is true about structure. For some people. That's the problem. For some people, it's stinking thinking, the emotional or spiritual side and You can see the studies on stress hormones inflaming or triggering type one diabetes and triggering autoimmune diseases was what we think that or how we respond to stress and the hormones we make that set that up. For some people. That's the trigger. It's all about finding the map. So my entire career has been based on always asking my first mentor, no, my second mentor. My second mentor was Dr. George Goodheart, the founder of applied kinesiology, the muscle testing that some doctors have seen. Practice night have hundreds and hundreds of hours with Dr. George and he would always every weekend in our seminars, and usually they were at the Marriott Hotel at the airport in Detroit. So people fly in from all over the world to listen to Dr. George and the the podium that he's stood on was a wood podium. And he would do this all the time. He would say, lift up his right knee and his right arm and go, Why doctor and slam his foot down really hard. So we all kind of jumped in our seats now, because that would stage would just like bounce a little bit. Why do they have what they have? Why is your patient complaining of dot dot dot? And he would consistently drill into us Why? So my entire career has been based on why is that happening? You know, for example, why is it? We've all heard that it takes 20 minutes before the hormones in your gut. Tell your brain that you've eaten enough? How come you don't feel full right away with the volume of food you take in? How come you have you eat a little bit more and they say, Oh, I'm really full. How come that messaging is delay. I don't really know. But doctor Ken , you might, you know, we could have some discussion about this. I just made this up. But I think it's because we have the same body as our ancestors thousands and thousands of years ago, bodies function exactly the same. And a primary concern for our ancestors was getting enough food. They didn't get three meals a day, they ate when they found food. So even when they're full, maybe they should eat a little bit more because they might not get it next time. And so they get an extra few 15-20 minutes of eating the berries or eating the nuts or a little more meat on a harvest they made because they might not get a meal for a day or two. And I'm just making it up as to why I've never seen anyone write about why that is that that happens. But that's that was my thought about it, but always why. So I've been asking why my entire career.Ken Brown 16:01 So the why this is really interesting. So the when was 1978? The How is these mentors that have come to you? And then the Why is how do I do this? So then the how I built this, where did you go from? Okay? I am learning a lot from these experts, I have decided to shift my career focus and put in you've put a ton of time into developing summits into writing books into I mean, your your website is just got blogs that are just stacks and stacks deep. So when did you make this decision to go, I'm going to really commit to this aspect. And I'm going to become a thought leader and a teacher about these kind of things. Because clearly, you're passionate. But the as, as a physician myself, it's finding that time it's saying I'm going to take this, this leap off this dock, say I'm going to commit to this. I feel so strongly about it that I'm willing to put myself out there.Dr. Tom O'Brian 17:01 My third mentor was Dr. Jeffrey Bland. Who I heard Dr. Bland first talk in Chicago in 1978. And he is the Science Guy. Ken Brown 17:15 78 was a big year for you.Dr. Tom O'Brian 17:16 It was a big year. It was a very big year, married in 77. Went to school graduate school in 78. met these incredible mentors. You know, I think my angels just guided me to these guys. It was unbelievable. And but Dr. bland would say now this doctor in the New England Journal of Medicine said this and oh here three years ago, in the British Medical Journal, they said this and right here last week in the Journal of American Medical Association, they've said this, do you see how these pieces come together? And Dr. bland has always been about asking why and understanding at a deeper level why things can occur from a science level. So Dr. Goodhart was all about clinicians and being a clinician and finding out how things work. And sometimes he made up the reasons because he wasn't as much of a science guy, as Dr. bland. so bland is talking why from the science goodheart is talking why from the results. And so what happened? Was I just with every patient, I just kept looking to see, why is that happening? Or if they're not getting the results that I think they should have gotten? Why is that not happening? What am I missing here? What am I missing? And so I kept I keep looking and looking and looking. I'm not content when they feel better. And I mean this with the greatest of respect, I don't really care how they feel. They don't come. They come to me because of how they feel. But they're really coming to me to have their bodies function better so they live a long and vital life and how they feel is transient. So whether I get them feeling better right away is secondary to identifying the mechanism behind why their body's not functioning properly, Ken Brown 19:11 love how you said that, so that how they feel is transient. And the first thing I thought of is how many people come to me. And they're on multiple anxiolytics and multiple antidepressants, right? And I read the notes from the other doctors and they're like patient reports of feeling less anxious. Plus, check. Beautiful, there it is. But now I'm dealing with side effects of eight different drugs. And so I like how you said that how you feel is transient. I need to know why. I love Dr. Tom O'Brian 19:38 Yeah, yeah, and of course, all of these drugs, the antidepressants, the anti anxiolytics. They're all approved and designed to be used for a short period of time. None of them are approved for the rest of your life. But they're given to people so they continue to feel less symptoms. Ken Brown 19:56 They're approved to be given for short periods of time, but the pharmaceutical and I'm not passing the pharmaceutical industry. Many of these drugs if you try and get off of them create a tremendous amount of their own side effects. So knowing that, so Eric Eric's former life, the way that he paid for his crna school was actually as a drug Rep. So he's got some pretty interesting stories about how to make sure that you move some product.Eric Rieger 20:19 Yeah, no comment, but I don't work there anymore. So that's probably the most important takeaway. No, but I do agree with that. And I do think Dr. Tom, one of the biggest issues that I never liked about certain aspects of pharmaceuticals, which were intended for short term, to become long term is they're missing a very, very important piece. Once I've taken this to alleviate whatever the symptom or the feel, as you put it, there's no exit strategy. There's no way for me to break this dependency that I've now formulated to make me now feel this new normal. And that's, that's something to fear. I would, I think, to engage long term with a pharmaceutical that's just simply going to function as a feeling band aid. is taking care of the issue.Dr. Tom O'Brian 21:02 You're absolutely right. You know, and we've got so many cases of people on high blood pressure medication or on antidepressants. And we always say at the very beginning, now look, here's what's going to happen. There are some side effects to the medications you're taking. And you may have heard some, but I'm just want to make sure you know, these are the potential side effects. But we're going to address why your body has high blood pressure right now. So it's great to be taking these medications. You absolutely take them when you need them, and you need them right now. But as we address the underlying why your need for those medications is likely to go down, which means you're going to stand up and you're going to start getting dizzy because your blood pressure is too low, because you've got too much medication now. So I want you to call your cardiologist or the doctor who put you on that medication as soon as you start noticing any symptoms like this, this, this or this and say, Hey, I'd like to come in, and you come in and you say, you know, I'm getting a little lightheaded when I stand up now, and I never did before, but I've changed my diet. I'm exercising, I think I need less medication. Can you monitor me and we meet down when you think it's appropriate and safe. But just gradually wean me down so that I don't have any complications as my body's getting healthier. And every doctor is willing to do that every doctor and if they're not find a new doctor to monitor your medications.Ken Brown 22:36 So I'll stop you right there. And this is more for teaching me and with your style of practice. You have somebody that comes in you know that they've got the diabesity triad or whatever. And you look at them you go Okay, we need to start someplace. Do you start diet do you start environmental toxin do you start sleep, because I think those are kind of the three pillars might leave least knowledgeable aspect of that is environmental toxin because it's just something that I've not gotten into yet. And when you mentioned the breathing in the spores, I'm like, Yeah, I've got a lot of patients that got really sick when they moved into an older home and they renovated and then they've never been right. Since I've definitely believe that mold has a big role, but it's just the amount of time. So when you look at this, I'm challenging you to say this is where I start first, where is it? Dr. Tom O'Brian 23:25 Really easy, really easy. There is a great program that's been developed called the living matrix. And the living matrix is a, I don't know 30-40 page questionnaires. And it's going to take you, Mrs. patient, it's going to take you a day or two to fill this out. You'll come back to it and fill out some more of it. Someone's going to say how is the health of your mother during your pregnant pregnancy with you? And he will say, Oh, I don't know my mother passed. That's all right. Call your aunts. Call your aunts and find out. Did mom take any medications during the pregnancy with me, you get as much information as you can, and when you have a completed living matrix, this is the computer model, the program sets it off into eight different categories. And it becomes obvious which categories are the most out of balance. And that's usually the place that you start. And we'll start with maybe two or three of those categories, depending on the individual. Some people, it's clear, their auto immunity happened within three months of their divorce, or within three months of being sexually abused. And it's clear, they've got to deal with that energy. And so that person needs to include in their protocol, a therapist that they feel really good working with about this particular topic, because that's not my category. But if it's not address, it's going to thwart the progress radically. Ken Brown 24:59 That is so interesting. That's that insult to injury that I have to have that discussion with so many patients where I have somebody that comes to see me and they're like, yeah, it's unfortunate. I went to this horrible divorce. And then I started bleeding out my rectum and then I diagnosed them with raging ulcerative colitis. So like, what is the bad luck? I'm like, I hate to attribute it to bad luck. I attribute it to a sequence of events. Dr. Tom O'Brian 25:22 Yeah, exactly. Right. I agree. Yeah, that is totally agree fully agree. And and the tool called the living matrix of every patient fills that out. I have lots of people, you know, we we did a docu series called betrayal, the autoimmune disease solution. They're not telling you is that out yet? Okay. It is it is. And we've actually had over 600,000 people watch it. When I make the living matrix available to people and I think probably four to 6000 people have filled it out. You know, it's great because it's hard to read until you understand how it works, but it gives you a lot of information. And all of our patients fill it out before I'll ever see them if they don't fill it out, or they fill it out halfway. I don't see them. If I if I see that it's only half done. I call my staff because I'm virtual now, you know, so I do virtual consultations. But as I'm looking at the results here, and I'm looking at the screen and living matrix, you know, if it's not filled out, I call my staff and I say rescheduled or they put the time and I'm not putting the time in until they do if they do it half ass, I'm not going to do it half ass, and so cancel them, and don't charge them just cancel them. And if they want to come back, do it right. You know, you just don't put up with that. And I talk on stage all the time to doctors. You can't put up with someone who's putting their toe in the water. They're either going to do a deep dive with you, whatever your skill set is or they're not and in our practice, we represent that our goal is to help them see the map of what's happened to them. And so if they can't, they can't see the map. If I don't know the history, it's not possible.Eric Rieger 27:16 Well, that's actually pretty, pretty impressive because in a different in a different way when we've had patients who've come through the clinic, and then we've, we've prepped them to, to scope and I'm addressing anesthesia and of course, Dr. Ken over here is discussing with them what to expect as they continue on their journey. Something I've heard him address is, it doesn't matter necessarily what led to where you are right now, whether it be your fault and all of them or none of them. But it is your responsibility to engage with the change that's going to make you better. And you've had that conversation with with plenty of patients and it really just doesn't matter what to this point we can identify the triggers, which of course helps finding the solution. But ultimately, there's going to be self responsibility for one's own health. And you've got to be able to commit to whatever that change happens to be. And I would say that really the the gut check project that this whole the whole reason for this podcast was, we felt that there are better solutions than just taking the old didactics from the pharmaceutical industry and antiquated medic medical school iidx to solve problems. Mother Nature has lots and lots and lots of tools that we don't all, you know, use which are free available. And if you just have the discipline to stick with it for your own interest, you'll find in most cases, a better health, healthy living style, I guess you could say, Dr. Tom O'Brian 28:48 well, you guys are in a unique situation that you have to do the tests to identify where they're currently at. You've got to be able to clearly say you've got ulcerative colitis, it's at this stage and it's in this area of your colon and Okay, so we need to calm down this fire, calm down this inflammation while we look to see where it came from. So you you guys have both areas that you have to address and I do this on stage a lot and you know doctors laugh at it, but I've had a number of people come back to me years later and thanked me that they implemented this. When I I tell patients that my favorite patients are the ones that say I've been to Mayo Clinic and they don't know what's wrong. And I'll say that's great. Congratulations. And they look at me kind of startled. You know, they heard I'm a nutcase. But Congratulations, that means you don't have a disease. Because if you've got a disease, Mayo Clinic would find it. You've got dysfunction, something's not functioning right. So the test we're going to do or not the same test that we're looking for disease, we're going to do functional tests. And I hope that we find some functional tests, and people will and sometimes their insurance won't pay for it. And then some patients will say, Well, I can't afford that. And I say, Okay. Oh, okay. And then I write down in their file. Patient refuses this recommended test due to finances? And please sign this. Well, why? Why would I sign that? Because you're asking me to work with one hand behind my back. And I'm going to do everything I can to be of service to you. I will do my very best, but I'm not responsible anymore. If a problem occurs that I miss something, because well, no, no, that's okay, Doc, I'll sign it. Okay. Or no, no, no, I'll do the test. I'll do the test. Okay, good. Because I've seen so many people that say I can afford it. And two months later, I see him in the shopping they've got a deep tan because they just spent three weeks in Mexico, on vacation. It's just a priority thing. And if someone really can't afford what they need, well, our services will always reduce our services for finances if it's true, but we need patients to take ownership and responsibility to be actively involved with us. as we're going through this process. Ken Brown 31:28 When you started this, you open with Alzheimer's and it's funny because I kind of do that with my patients where you said that one in three people will now develop Alzheimer's. And then you tell me Alzheimers Association says that Alzheimers Association, so and then you talk about a patient that cannot afford to do X, Y and Z but you see them with a deep tan. So I use the let's fix your gut to protect your brain later in life. Because I'm I personally and I try and teach my kids this. I've got a 15 year old, a 13 year old. And my wife and I are on the same page where I personally prefer to purchase memories, as opposed to things. So I'm perfectly willing to take us on a trip, have some incredible meals, have some great pictures that we'll revisit. And rather than purchase something else, and what I mean by that is what is that memory worth? That memory is worth so much more than that object to me. And then if you were to say that I'm going to take away all those memories, meaning I'm going to take away your life, that's the panic moment with me, that's when I want to sit there and say, I want you to change your diet, I want you to change your lifestyle, not even so much is it so much a physical thing. It's not so much so that you can have the Beachbody, it's not so much you can do this. It's so that we protect your brain later. It's so that the same concept of osteoporosis prevention in your 30s so that we're not dealing with it and you're 60 so you're not busting a hip in your late 60s. And then now thing, what you're talking about, it's so true that you, it's hard to get people to think big picture like that. But you've always done this. So 1978 you have these mentors that do this. When did you decide to really say I'm going to be part of the movement? And I'm going to develop this website? I'm going to spend, I mean, you've been prolific. You've written books, you lectured you do some crazy summits. Man, you're gluten summit. Some of the people you have on that are like my heroes. I mean, Alessio Fasano, I mean, I've been following that cat since you know, early on in his career and a lot of you get some some pretty heavy hitters. That's pretty impressive. How did you go from, I now need to make a difference. On a greater scale, I guess is what I'm saying. You've mentioned multiple stages and stuff like that. When did you go it's less from one to one it's more from one to many.Dr. Tom O'Brian 33:53 January 2013 my friend, I think our friend I believe, you know, JJ Virgin. I've known JJ for many, many years. And she used to call me or I'd see her and she said, I just went to this weekend seminar was fabulous. You know, they're talking about this marketing concept of how to get information out to people in sales. He she said, You should come and say, Oh, yeah, thanks. Thanks. And then she hired a consultant, Allie, and he called me and said, I just signed the contract and I'm working with Allie. I'm gonna learn how to do this at a bigger scale. Come do it with me. Yeah, how much? $10,000 it ain't happening here. It ain't happening. Right. And then JJ grew and she grew. She applied to Princeton. Ken Brown 34:45 JJ is pretty convincing. when she gets passionate predicaments. Dr. Tom O'Brian 34:49 Yeah. And then she called me and said, Look, I'm having a seminar. I'm having I'm hosting a seminar, you're going to be there. I'm going to hire somebody to come grab you by the nape of your neck and bring okay, okay. Okay, welcome. So this is January 2013, dropped my jaw to hear how the participants there would do one thing that they prepare a webinar or something. And they would have 200 people attend, or 400 people attend just drop my jaw of the impact factor that was magnified by learning how to use the internet. And so I made a declaration that weekend. I said, you know, I'm a geek, and I just read a lot of science and I know these guys are I've been in their seminars where I've seen them at symposiums. I'm going to interview a number of geeks from around the world. And I'm going to put it online. Would you everyone here in the audience helps support me in this by send out announcements. And they all said yes. So my first interview, you'll really appreciate this Dr. Ken. My very first interview ever was Professor Michael Marsh, and our the marsh Godfather, the Godfather, celiac Marsh one Marsh to Marsh three, the Godfather, and he and no one had ever interviewed him. He was 74 no one had ever interviewed and he took me by the arm and walked me around Oxford and said, Tom, that's, that's right, right where I stood, and that and I received my medical degree in 1962. So that's great professor or took me down in the bowels of the library from the 1800s and that's where he sat to study every day. And you know, so Marsh, the Godfather and Professor Fasano, Harvard and so many others from around the world. Umberto Volta chairs the celiac Society of Italy. And I interviewed all these people. And everyone who's a JJ's event, sent announcements out to their people. We had 118,000 people attend Luton summit in November of 2013. It was the first online. The first online health summit ever was the gluten summit. And we made it up. Ken Brown 37:25 And that was when 2000 what? Dr. Tom O'Brian 37:27 November 2013. Ken Brown 37:30 I mean, thousand of those people were still doing dial up. Yeah.Dr. Tom O'Brian 37:35 That's right, you know, and the weekend I came back from making that declaration, I mean, I was fired up. I get a message. And this guy emails me and says, Hi, my name is Bob Roth. I am the social media director for the University of Chicago celiac center, and I'm out in California. I'm wondering if you did have time for breakfast, and I said, You i'm sure so we had breakfast and Bob said, you know, Dr. O'Brien, everyone's University Chicago thinks you're a nutcase. You talk about you talk about gluten sensitivity outside of celiac disease. And but I watched one of your presentations was recorded, and you're just talking science. I said, Yes. You said, you're actually correct. And I said, I know. I know. He's and I said, Listen, Bob, I just made this declaration. I'm going to do this thing. I'm going to travel the world. I'm going to interview these guys. I know who to interview. And I'm going to interview them. We're going to put it together and we're going to do this thing online. Come join us. So Bob left the University of Chicago celiac center, and came to Southern California and was our social media person. And then we found a guy to who knew how to run this program I learned about in jjs weekend called InfusionSoft, which puts puts all the data together into one package and sends it online. And we hired Bobby from Tennessee. And we put on the gluten summit. And the next day, I mean, so many of my friends call him said, How did you do that? What did you do people like Deanna Minik and Mark Hyman and so many other my friends, how did you do that? And I said, Well, my friends helped me here. And they said, Oh, can can are my staff and we just made it up. When there was a problem. We made it up. And they said, can I talk to your staff. And I said, Sure. Then my staff came to me and said, Hey, Doc, they they want us to do this for them. We should start a company to do this. And I know man, that's not my thing. That's not my passion. You guys go ahead if you want to. That was the formation of health talks online which is hosted 10s of millions of people in the last seven years in different summits all over the world, they of course, that's where it came from.Eric Rieger 40:09 Sorry about that. I didn't mean to talk over you. But of course, you wanted to have people that were interested in what it was that you were offering. You also find some inspiration in the fact that there were that many like minded people who were essentially as you probably assumed, but now you confirm they're kind of starved for that information.Dr. Tom O'Brian 40:27 Oh, I knew I knew from the day I opened my practice about the frequency of weed related disorders outside of celiac disease. I knew it. The testing was just not accurate enough at the time to confirm it. But I put people on gluten free diets and they get better again and again and again. But it was a component of a treatment program, not just gluten free diet, but it was a prerequisite you have to do that. Sure, guys, I see that the battery on my computer's at 5%. I have to run into the other room and get the charger So I'm going to come right back to you. SoKen Brown 41:04 we're gonna love this. I love this conversation. So what's really cool about Dr. Tom is just how honest he's being. He's just like, Hey, I met this guy. He taught me something. I met this other guy. He taught me something, I met this, JJ comes up to me and says, Hey, come over and do this, and just pulls the trigger and says, I have a message that I interview out there. And the digital marketing era was really in full swing. Right then.Eric Rieger 41:30 the thing I felt the reason why I asked Darshan that last question was, to me it was it was eye opening, even when we met JJ is just seeing how many people were now gaining access to topics that simply were not being addressed when when we were young, or going through school, etc. And basically what I feel like Dr. Tom just illustrated here is technology has allowed us to take what has been either ignored or hidden messages out to the masses and then helping people where they couldn't find help before. Ken Brown 41:59 Yeah. Are you back with a Tom?Dr. Tom O'Brian 42:02 I'm back with you. And as, as, as you were talking about technology absolutely correct, you know, for years and years that they thought I was a nutcase because I would talk about wheat related disorders outside of celiac. And now we have the testing available that's very, very accurate 97 to 99%, sensitive and specific. And so with those kinds of tests, the test is called the wheat Zoomer, could you zoom in on problem? And with those kinds of testing, people see for themselves that their immune system is trying to protect them, whether they get sick when they eat it or not.Ken Brown 42:43 So you've said this three times now, which means that it has clearly been a part of your career you said they said I'm a nutcase. They said I'm a nutcase. They knew I was a nutcase. So you've stuck by this, but will you explain a little bit when you say that, they say I was a nutcase. That meant that as a chiropractor discussing these other aspects infringing on people's territory, was it that you were just so far ahead of the curve that nobody was discussing? I want to know why you feel why you Dr. Tom feels that other people viewed you as a nutcase?Dr. Tom O'Brian 43:20 Oh, it was obvious. It was spoken about. But the the point in that is, you know, when when you know, that science is on your side, but technology just hasn't caught up yet to confirm it. And you know, it's on your side, because you see the results again, and again, and again and again, and you keep seeing the results, but you the technology just hadn't caught up yet. Then either you go by the status quo, with all of these unexplained applications, and people Don't get well, they're the way they're supposed to, or are you willing to break new ground and say, you know, oh, no, as is negative, when they give up wheat, they feel so much better. Why don't you try it for three weeks, and let's see what happens. Well then, and they get better. Their their child's attention deficit gets better. And the teacher say the new drug, you've given your child's working really well. And it was just a gluten free diet. The other parents say, Oh, we, we didn't give them any drugs. So he's on a gluten free diet. And you see that again and again and again. I can't let what other people think of me get in the way of the service that I can do for my patients.Ken Brown 44:50 Because you took a really bold let's, let's dissect what you just set about that. You knew that certain people in health care, we're not saying the nicest things about you. And then you dove in when you said I don't want to treat a patient that just sticks their toe in the water, you dove into a digital marketing world where keyboard warriors love to play also. So you went from I know that some people are going to say not nice things, too, I'm going to embrace it on a level that nobody ever has. And I'm gonna teach online, which is a very, very bold thing, because not a lot of people have the guts to do that right. To be pushing the envelope. I mean, it's, you know, I mean, you talk about I've been talking about zonulin for years before we test it. And you said we'd Zoomer and that's how I got involved with vibrant wellness. I was like, Ah, you guys figured out how to check zonulin? Yes,Dr. Tom O'Brian 45:49 yes, yes.Ken Brown 45:51 Yeah. And when I talked to my colleagues, I mean, even when I talked to gastroenterologists, they looked at me like you're What are you? Are you one of those? nutjobs talking leaky gut. You're one of those weirdos talking gluten sensitivity. Um, you know, fortunately, I fortunately did not discover the internet early enough so I didn't have to put myself out there and have a successful career writing books and doing stuff like that. Fortunately, I still have to stick my finger in people's butts to make a living and occasionally interview somebody who's smarter than me that decided to put it out there on the internet and do things and do summit so that's a but it takes guts to do that. So are you there. Dr. Tom?Eric Rieger 46:35 Did he freezeDr. Tom O'Brian 46:37 sn Ken Brown 46:38 you froze there for a little bit.Eric Rieger 46:41 We can hear you. Okay. You guys go. How about that?Ken Brown 46:45 Okay. There we go. Okay, back now.Dr. Tom O'Brian 46:47 Okay. Yeah, sorry. Yeah, you're absolutely right. You know, you asked me why and how did I do this? A home that I have in every one of treatment rooms. Can Can you hear me? Okay?Ken Brown 47:13 Yeah, you're going in and out a little bit, but I think it's all right. Oh, we should go ahead and muscle through it. That's right.Dr. Tom O'Brian 47:19 Okay, okay. There's a poem that I when I read it I just resonated deep deep in my being. It's by George Bernard Shaw. This is the true joy in life, being used for purpose recognized as the Mighty One. The being a force of nature. Instead of a selfish, feverish little clod of ailments and grievances complaining The world will not devote itself to making you happy. I am of the opinion that my life belongs to the whole and it is my privilege to do for whatever I can, life is no brief candle to me. It's sort of a splendid torch that I have a hold up for the moment and want to make burn as brightly as possible before passing it on to future generations. So that's my creed.Ken Brown 48:18 I love it. I love it. It's awesome.Dr. Tom O'Brian 48:20 And and from that place, if you know about zonulin, and you know about leaky gut and you think a patient's got it and you don't address it, because of what our peers may think, in my mind, it's Shame on you. And I do that on stage with doctors all the time, who cares what your peers think? I'll give you an example of that one, and you'll appreciate this one 1986 Australia. gastroenterologist says, You know, I think that sometimes ulcers are caused by a batch said you are a nutcase. Everybody knows ulcers are caused by too much acid and you have to give antacids so what did this guy do? He does an endoscopy, puts a camera down into his stomach takes pictures of the healthy pink tissue of his stomach. And then he drinks a beaker of beaker of a bacteria called Helio backer pylori. waits for days until he's as sick as can be, does another endoscopy takes pictures of the many ulcers that are starting in his stomach, and then he takes the antibiotics to kill the bacteria waits about a week until he's feeling better, does another picture of the healing of the ulcers. Then he publishes that paper, then everybody knows he's a nutcase. But he proved the under shadow of a doubt sometimes, ulcers are caused by a bacteria and the World Health or I thought that was so important. They sent that paper to every medical society on the planet. Why? Because at that time, stomach cancer was the number one cancer killing people. And it often comes from a helium backdoor infection. So, this guy didn't care. You know, he didn't care. He done his work, and he still was kind of thought of as a weirdo out there. Dr. Barry Marshall. 21 years later, he wins a Nobel Prize in Physiology. And the Nobel committee says and this is the exact quote, who with tenacity, and a prepared mind challenged prevailing dogma and that's what every one of our patients needs.Ken Brown 50:49 a prepared mind. I like that exact word mind if you if you're tenacious, but you do your homework, you burn the midnight oil, the prepared mind with tenacity is an unstoppable force. That's awesome. That's love thatDr. Tom O'Brian 51:05 is just one hour a week. That's tenacity every Tuesday night after dinner every Sunday morning after services whenever it is, but every week, you're going to spend one hour learning more about reading the map of how you got to where you are just one hour a week. And in six months, you've changed the way you think you change the way you live your life. You challenge prevailing dogma, and your health is the benefit that you get from it.Eric Rieger 51:34 I love that. Ken Brown 51:35 I love it. IEric Rieger 51:36 mean, it's interesting that you use Marsh as that example, because when this guy sitting to the right of me developed Atrantil and went on to talk about why polyphenols are so incredibly important. I guess we're going on six years ago now. He used that example. And that it's okay to think outside of the box which is essentially what he was saying to challenge dogma is to go outside of this box that we have built around ourselves. If it weren't for someone venturing outside, we never would have made innovation. Ken Brown 52:08 And the beauty of the technology that has allowed you to have this stage where 600,000 people sign up for summon at one time, also allows us to share globally information in a way that we couldn't before. So when I sit there and meet with some of my colleagues, and they're like, oh, there's no science on that. I'm like, Oh, really, let me pull up my Mendeley account. Really, here's 8000 articles on what we're talking about. Why don't you start reading that and when in my world traditional medicine world especially in Texas, I think that different states a little more progressive, like California has always been a little more open to the functional medicine side but Texas, not so much coming around. But when the drug rep to my left over here when doctors say there's no science on that what they're saying is somebody is not brought me lunch with a detailed piece explaining what I'm supposed to say. That's really what I'm saying. And we're all really busy. And that is what it is. But it just happens to be just like you. You go, um, you know, I'm tenacious, but I'm armed with science, therefore, I can walk into this battlefield and hold down, even if they even if they call me crazy.Dr. Tom O'Brian 53:17 Yeah, cuz that's exactly right. Last week I did an interview for a neuro psychiatric psychiatry group. And the doctor who coordinated the interview, she said, you know, Dr. Brian, I heard you speak three years ago at our conference, and you yelled at us on stage. No one's ever yelled,at us on stage before your neuropsychiatrist they're the cream of the crop in their own mind. You know, they're legends in their own mind. Right. AndKen Brown 53:48 voices in their heads.Dr. Tom O'Brian 53:50 Yes, right. Good, catch. Good, good. But what I said to them if you aren't spending one hour a week, reading the current literature Cutting Edge literature in your field of expertise, shame on you. You're outdated, one hour a week. And nobody's got time for any of this. But if you don't do that you're outdated within a year. Yeah. And, and she thanked me. She said, You know, I took what you said to heart because it made sense. I didn't like how you said it, but I liked what you said. And the result is I've completely changed my practice in three years. Thank you so much. I really want to acknowledge you here on the microphone in front of all of my colleagues, that was such an excellent recommendation to us and i and i say that to everyone. Whether you're a general public, or a health care practitioner, one hour a week. That's what it takes to have 10 that's tenacity and then prepare your mind to challenge the way you think so that you can read the map of what's happened to your body so far,Eric Rieger 54:58 don't you one of the reasons why really enjoy doing our show is that I'm a better doctor because of it because I prepare for different things because I have to research a lot of stuff. When we talk about topics. You're the exact same way you have gone. You started with the gluten and the you went to the brain. You're looking at this now you've got different you've got the whole erm. Dr. Tom O'Brian 55:20 bottle immunityKen Brown 55:21 Yeah, but what's the name of the of the program again?Eric Rieger 55:25 betrayal, Ken Brown 55:26 betrayal, betrayal. Yeah, I was I was trying to think of that. So when you do that you automatically your passion will have you read this. So I'm going to ask for your help. Maybe it's not you. Maybe it's some other people that you meet, but we're running into something. So when I say my Mandalay account, I have a graduate student that I work with and she finds everything If you need anything, let me know just email me She will find it and get the articles and so we can sit there and look at some of this but I'm seeing something and I think that you're probably seeing it also and it is This weird it becomes down to a nerve, dysautonomia motility type situation that can be the underlying cause of a lot of gastrointestinal issues which then lead to neuro inflammation. And now we're getting to the vagus nerve and we're talking about this I've got some really sick people that come to me and they're they've all been to the Mayo Clinic they've all been to the Cleveland Clinic and they all have been told that it's functional this and that, that it's in their head and they all say you should start taking Prozac but these are really intelligent people really type a people that had very successful their attorneys or accountants and this and that. I'm seeing a trend here that the chronic disease is affecting the nerves that is it acetylcholine Do we need to start working on the you know, the, the vagus nerve, I don't know. But I it just feels like more and more people are showing up there. They're really trying what's your what's your take on that? Because if we can figure this out. That's it.Dr. Tom O'Brian 57:00 This is this is a PhD discussion that we're now getting into that is at the core of the answer to your question. Arguably the number one journal in the English language for children's health is the journal Pediatrics put out by the American Academy of Pediatrics. They published a policy statement, which means it's not an author, you know, if I were to get an article published in pediatrics as an author, I've scored top tier difficult journal to get into I've really scored but this is a policy statement. That means it came from the board of the Academy of the American Academy of Pediatrics, and they said the toxic substance Control Act failed miserably to protect our children and princes and adults. And it is The governing legislation at the federal level for all chemicals introduced into our environment. This was passed in 1976. It's still the regulating guidelines for all chemicals introduced into our environment. It the the guidelines are so cumbersome, that in 40 years, they've only regulated five chemicals or classes of chemicals in 40 years. Because the lobbyists were so successful in paying off the senators and the representatives to pass this legislation that has no teeth. The legislation says you have to show that the amount of whatever chemical a person is exposed to is toxic to them. When you pump gas and fill your tank with gas, can you sometimes smell the gas? Sure, of course. you're smelling benzene,Ken Brown 59:09 right? Oh, yes.Dr. Tom O'Brian 59:10 Benzene going up your olfactory nerves right into the brain triggering inflammation killing off brain cells right now. Right? It's killing brain cells. But there's no evidence that the amount of benzene it's inhaled while pumping gas is toxic to humans. There's no evidence you can't. There's no evidence that it causes a problem. But give me 30 years of smelling benzene once a week and how many millions of cells you've killed off. I'm warming up now. 2017. papers published that came out of Chicago 346 pregnant women and the eighth month of pregnancy They did urine analysis they measured Phthalates five Phthalates Phthalates are chemicals used to mold plastic. Most of us have heard of Bisphenol A or BPA Corona is one of the chemicals. They measured five chemicals. There are hundreds of chemicals but they just measured five. they categorize the results into quartiles, the lowest, the next, the third and the highest quartile. They then follow the offspring of those pregnancies for seven years. When the kids turned seven years old, they did Wechsler IQ tests on the official IQ test. There's not much in medicine, that's all or every This was every every child whose mother was in the highest quartile of Phthalates eats and urine and pregnancy compared to the children in the lowest quartile of Phthalates and urine and pregnancy. Every child in the highest score tile, their IQ was seven points lower than the kids in The lowest quartile of Phthalates seven points. That doesn't mean anything to anyone until you understand one point difference is noticeable. A seven point difference is a difference between a child working really hard getting straight A's, and a child working really hard, getting straight C's, right this kid in hell because his brain never developed properly. And then just go to Google and type in Phthalates and neurogenesis, nerve growth. Here come all the studies, how balades inhibit nerve growth. And you see this and you wonder why Autism is going up and attention deficit is going up. You see this and then you go back to the pediatrics article and you read that is 247 pounds of chemicals manufactured or imported into the US United States every day for every person in America 247 pounds, that's 27 trillion pounds a year, take the population of the US multiplied by 247 times 365 days, it's 27 trillion pounds.Every newborn child in America has at least 200 chemicals in their bloodstream at birth that aren't supposed to be there. Many of them are neurotoxins, brain time. You wonder why we're seeing this increase in disease. We all are walking sewage dumps, excuse me, but we are we all are because it's in the air. You if you sit in a room and you can see the sunlight coming through the window, sometimes the right time of day the angle and you see little dust in the air. That's what you're breathing. That dust is the family lychee From the plastic lines in the windows, they leach out family chemicals into the air for years. It's the scotch guard on the sofa, leaching out those chemicals into the air for years. It's the formaldehyde in the kitchen cabinets. If they're not solid wood, they're pressboard. They're soaked in formaldehyde, and the bathroom cabinets leaching out into the air for years. And we were exposed to all of this, all of that and we're walking sewage dumps. You wonder why degenerative diseases are going, why Alzheimer's and the number one type of Alzheimer's is inhalational Alzheimer's, it's what's your breathing. This is so overwhelming for people. When you get when you look at this map. When you see what's happening. It is so overwhelming. That's why you have to operate from the platform of one hour a week. Yes, because and so one week When you learn that the leftover chicken from dinner, you put it in a plastic storage container in the refrigerator. The next day the chickens got phalates in it from the plastic. When you learn that one week, you take that hour you go into my book and there's the three URLs to order glass storage containers, and you go to miles, kimball.com and Amazon, whatever the third was, Oh, I like those. And yours three round ones in two square ones and one for the eyes. You pay with your credit card, you hit send, it took an hour, you're done for the week. Like that. Never again, will you poison your family with minute amounts of foul aids from leftover food in a plastic storage container. Now, there's no evidence that the amount of families that leach out of plastic storage containers is toxic to humans. That's how they get away with that crap it is. That's how they've gotten away with it. And it's the it's the The indoor and just read the science indoor air pollution is much worse than outdoor air pollution in most areas of the country. Because we don't think about our homes we don't think about the formaldehyde, the benzene, trichloroethylene that we're inhaling, then you go to my book and there's the study with the graph that the study from NASA that shows to six inch house plants, and there's the list of all the house plants that do it to six inch house plants and a 10 by 10 room absorbs up to 70% of the toxic chemicals in the air.Ken Brown 1:05:37 warmer times. This is the front so now you're scaring the snot out of me, but now you're giving me a solution. So you're saying when your book can gotDr. Tom O'Brian 1:05:43 a Kleenex, hand him a Kleenex to get the snot and to six inch houseplants, and there's about 12 or 14 different types of houseplans six inch houseplants absorbable To 70% of the toxins in the air in a 10 by 10 room, they're absorbed through the leaves, they go down into the roots, the microbiome of the soil breaks that stuff down. They produce oxygen and put oxygen into the air to 10 by 10 to six inch houseplants for a 10. By 10 roomEric Rieger 1:06:17 solution.Ken Brown 1:06:18 Yeah, it's a solution I'm all about so and so your book is not just teaching people what to worry about, but you're like, this is the solution. So the one hour a week is I'm going to give you one hour a week solution. And if you continually do that, by the end, you're going to be a healthier person.Dr. Tom O'Brian 1:06:35 You know, everybody wants solutions. Nobody wants to hear about the problem. But there's no way you will have the tenacity to do this. And at a pace that you can do it and not be overwhelmed. That's why it's one hour a week understanding. You are going to be overwhelmed, but you're going to do bite sized pieces pieces of this. And in six months. You've got it. You've changed your life. Your husband Using the Tupperware containers to store nails in the garage, right? I mean, you've got all the the dishwasher, you'd never run the dishwasher during the day. Because the toxic chemicals that come out of the dishwashing detergent, when they get heated up to 160 - 170 degrees, they leach out of dishwashers are not airtight. They're watertight, they're not airtight, and those chemicals are in the air, you're sucking those fumes. You only run the dishwasher at night when everybody's sleeping. And you've got to learn all these little things because the paradigm that we've accepted the prevailing dogma that we've accepted about the way to live life and about our homes is killing us. It's slowly killing us. This is why your patients are coming in with more confusing results is because they're loaded full of all of these toxic chemicals. How many of us have been watching the chem trails? For years to say, Oh, that's really something you know that that's too bad. Yeah, I wonder what that stuff is. And we've never done anything about it. We're sucking the fumes of all those heavy metals that were being spewed into the air.Eric Rieger 1:08:12 Yeah, well, I do want to add something here. I know that we've been it didn't seem like until just looked. But we've been talking for a good while. And I need to also give you some praise since you were the first to utilize the digital internet to reach so many people. You also have one of the most kick ass URLs I've ever seen. Yeah, so what is it? We do? SoKen Brown 1:08:34 we haven't ever joked about this? I was like, how in the heck did that guy get that URL?Dr. Tom O'Brian 1:08:39 1996Eric Rieger 1:08:42 the URL to link up with this very Dr. Tom O'Brien is the doctor.com and I want to say that one more time the doctor.com but you have the Dr. Yeah, I'm sorry. Yeah, you're the Dr. calm. So Dr. Bri ER doctor abbreviated v dr.com. dr.com will connect you with Dr. Tom O'Brien. But you also also have two specific programs for our listeners. One is to do that with a / betrayal to get on to the train of exactly the training that you're talking about and the other one, and I'll put, I'll put this in show notes, everyone, but the other one is thedoctor.com/kickstart. And if you want to do a quick rundown on exactly what kickstart is, that way, everyone in our universe can hop over and learn a little bit more from that from that with from you. Just tell us a little about thedoctor.com/kickstart.Dr. Tom O'Brian 1:09:36 You bet that Thank you. The kickstart is a number of handouts for you. They're going to talk about how to detox your house, how to reduce electromagnetic pollution in your house. What are the house plants that will suck up toxins? There's there's a handout for the kitchen there's a handout for the bathroom. There's a handout for the bedroom, all a number of different handouts so that you've got Steps to implement right away and you take them at your own pace, you'll get the plastic storage containers out of there, order glass storage containers, things like that.Ken Brown 1:10:10 Dr. Tom, I want to interrupt you real quick because you've hit a nerve with me here this is I just don't have the I'm always I spent a lot more than just an hour a week. But I spent an hours a week looking at the stuff that I'm interested in. And I have a blind eye to what you're talking about. And what you just said is I'm going to give you solutions. You can put a handout up, you're just going to go do this, this and this, because I believe you and I, I don't want to read a whole book about why I should get rid of my plastic just Just tell me how to how to fix it. That's what I like. kickstart seems like a really cool program for that.Dr. Tom O'Brian 1:10:46 Oh, thank you very much. And if you were my patient, I'd be all over you. That you can't do that because it's wanting solutions that has gotten us into trouble. Oh, gotta understand. All of you. The map of what happensKen Brown 1:11:01 this where you start yelling at me like you did on stage.Dr. Tom O'Brian 1:11:06 Because if you don't understand that mold can be a huge problem for Mrs. patient. When you go on vacation for a week or two, when you come home, you have to open the windows to air the house out. Oh, yeah, you got mold. You have to have the house remediated, you have to have a professional come Well, I don't have a problem. When I'm here. I don't feel anything. It doesn't matter if you feel it or not. If you're inhaling it, it's going up to your brain. And it's the number one trigger for the development of Alzheimer's is in halation, Alzheimer's, it's what you're breathing. So if your brain ain't cooking the way it should be, it's cooking in the wrong direction, you're too much on fire. You have to identify where it's coming from so you can get all the house plants you want. But if you still got mold in your bathroom, well it's not too bad on the tiles there. You know, it's just on the grout in between the tile that's not too bad. We'll Put that on your tombstone. It wasn't too bad. You know, it's critically important that we change our paradigm so that we understand what our individual map is, what has gotten us to where we are, because that map is going to change, you're going to get better because you implement the things in the handouts. That's great, you're going to get better. But a year from now, two years from no

COVID-19 Files: Ep. 10

university texas alzheimer's disease bones san antonio gas ftc ibs happy life sibo bloating md dr polyphenols ken brown atrantil

Play Episode Listen Later Aug 27, 2020 56:15

Eric Rieger 0:00 All right, welcome back to COVID files. This is actually an extension of COVID files number nine, so we used to call them 9.5. When we brought in Dr. Ackerman, we just call it nine plus,Ken Brown 0:12 man, I think we ought to call it COVID file 10. It actually deserves its own thing. Now I understand that you've gotten some, some listeners that maybe were a little bit dismayed by how we ended the last podcast. Can you go ahead and get everybody up to date in case they didn't see it?Eric Rieger 0:28 So there's there's actually a lot of things to attack number one, we had covered phone number nine, and COVID File Number nine, we talked specifically about the NRF two pathway. And we laid it all out there leading people up to the fact that how do you supplement the NRF two pathway because of how beneficial it is. If you've missed that. Don't watch this episode yet. Go back check out episode number nine. It's going to really lay the groundwork for this episode of COVID file number 10. Second thing, this is our first time this is my co host by the wayKen Brown 1:00 But why don't you can write a long time since we've been together this close without without a mask on? We work together with a maskEric Rieger 1:05 No kidding. Ken Brown 1:06 But you know, thank goodness, it's easy to get tested now. So at least I know as of this moment your test was negative. My test was negative, we can be this close together. Eric Rieger 1:13 at least for as good as the test was. Yeah, it says that we're negative.Ken Brown 1:17 And I'm super excited that you're able to multitask during this podcast. Oh, yeah. With you being so Eric, as you can see by the headphones, that he is a dual timing is a air traffic controller. Is that correct? You're getting feedback there. Is that why you're wearing headphones? And I'm not that is why I'm wearing them. Go ahead and raise your altitude.Eric Rieger 1:37 Bet Yes, that's we're doing a little bit of double duty. Here we are in the studio. But we're all alone. We don't have anybody helping us. Paul is still doing a fantastic job of doing the production after we get finished recording. But for right now, we're keeping our exposure to a minimum because this is the first time that we've been this close. Ken Brown 1:54 Yeah,Eric Rieger 1:55 We've got a mask onKen Brown 1:55 It really is. And you and I have worked together this whole time. Yeah. Several times a week. But we have a Had a 95 mass on and so at some point you got to start to, you know, push the boundaries a little bit, we've got to get the studio, let's go ahead and do this. And why do I feel comfortable about this because what we're going to talk about today is an extension of last podcast, check it out. It's about the NRF two pathway. We'll recover that really quick, just briefly go over it. But I'm going to tell you how the NRF two pathway can be very effective in overall health right in multiple ways, but also the possibility that there is compelling evidence to show that if you do not have a healthy NRF two pathway, then you are at risk for getting COVID-19 Eric Rieger 2:39 Yes. Ken Brown 2:39 So you and I are trying to do everything in our power to make sure that we have optimized our bodies in case we get exposed. Last episode we talked about how Joe Rogan's always saying why don't healthcare workers talk about how to prevent getting it that's what that whole show was about? Definitely. So it was about the last episode we talked about the NRF two pathway. And so today, what I want to discuss are some papers that I have found that show how to use certain natural products to improve your NRF two pathway. And that's right where we ended, we ran out of time last time, but specifically how this could be a new target to actually prevent SARS cov. Two, which is the virus that causes COVID-19 and reduce oxidative stress and inflammation while improving your immune system overall, and down regulating these two receptors, so it's kind of crazy, because it's like the panacea when we start talking about this pathway. And I started looking into these different papers. I'm like, why isn't anybody talking about it? Right? And I think that frequently, you and I have kind of pushed the boundaries a little bit and talked about stuff before everybody else was because we're, well, because we're just two turntables and a microphone. Because we have the access to some microphones.Eric Rieger 3:52 It's just yeah, access to microphones. But even more importantly, it's science based. What we're doing is we're staying true to the whole order. Have the origination at origin ation origination of the program which is we're finding compelling evidence to talk about as it applies to not only our but your healthKen Brown 4:10 yeah and so I think something that we have the ability to do is that been in healthcare and having access to wonderful people that help us out like Angie cook where we can get these articles that say Angie I want to talk about NRF you know, just unloads incredible articles on me and then we go through and sift through this. It's essentially what we're not making any claims. We're not saying anything to run out and this is what's what you should go do remember the disclaimer is, although I'm a doctor, or crna, we are not your crna and your doctor if you do have anything unusual going on if you have that weird rash or if you believe that you need to dogmatically look at something that we're talking about here and say I'm gonna do this, it's gonna protect me that's not what I'm saying. Talk to your doctor. What we're giving you is information. We're giving you science backed information. You do with that what you want. Ideally, I want you to take it to your doctor. And say, look, these guys are talking about this right? We should be talking about this. Right? So that's sort of the disclaimer right there, but it's all based on science. So, recap. We did talk about the NRF two pathway and we discussed how ridiculous the acronym is the acronym is nuclear factor, e two factor related related factor. I'll say that one more time nuclear factor, e two factor related factor, hence the f2, which is really funny. All right, it's the master regulator of cellular health, and it detoxifies all your cells. It stimulates cellular defense, and if any type of insult starts happening that protects the cell, specifically when we're talking about SARS, cov two, it actually down regulates the h2 receptor which allows the SARS cov to to attach and I'm gonna throw in a new term that we did not talk about last time because now it's relevant. The in normal conditions your NRF two pathway remains suppressed and kind of controlled like a cage using something called the cytoplasma repressor protein keep one that is the KE AP one. Talk about bad acronyms that's ever decided the NRF two decided that the keep one. The acronym stands for kelch like erythroid cell derived protein with CNC homology associated protein one cannot make that up. Like whoever was discovering this did not go to any acronym training at all. Now, we thought the NRF was bad. Now I'm going to tell you that there's something called the keep one protein, which doesn't allow your NRF to become activated. This is going to be relevant when we get into the next interesting. And so in response to any type of damage or attack or oxidative stress, the NRF two will actually separate from the keep protein which is controlling it, dive into the cell, hop into the nucleus and then turn on On 250 jeans, that's what makes it so amazing. Wow. So it says one thing that does this. That's why it's the master regulator. So in the last episode we discussed about how the role of the NRF two pathways beneficial in brain inflammation, cancer prevention, autism, environmental toxins and pollution, all based on studies and we discussed all that anti aging, dementia. In addition, we discussed about how if you do not have a properly functioning NRF two system, this can lead to obesity, diabetes, hypertension, and we know that if you are obese, older have high blood pressure or diabetes, you're at significant risk of having a bad outcome from SARS COV2 COVID-19. Yeah, Eric Rieger 7:45 And don't forget premature agingKen Brown 7:48 and the whole premature aging I thought. On our last episode, we discussed how obesity comes down to cellular oxidative stress. You may be a little overweight because your cells are struggling to get rid of the oxidative inflammatory process early on, right. So all right. So we also discussed how SARS COV2 make ourselves more vulnerable, because that nasty little virus, the pandemic that's screwing us up, actually works to suppress the NRF two pathway, it knows that NRF two is going to kick its ass. So it does this whole thing where it tries to overwhelm your NRF two pathway. That's why we believe that certain people are at higher risk for having bad outcomes. It it's a bully it picks on you know, I'm going to find somebody with a weakened NRF two pathway.Eric Rieger 8:38 What was the what was the analogy? We came up with cutting the phone lines before you break into a bank? Basically, we're stopping the ability for the rescue mechanism to work. We're not allowing it to work.Ken Brown 8:49 Yeah. So the biggest question we have here is that all these people are being exposed. Why do some people go through these horrific things? Why do some people have long term residual bad outcomes like pulmonary fibrosis and stuff, right. And now I'm learning step two that nobody's talking about. The virus seems to do this much more effectively and have much more deleterious outcomes when people have these other diseases, which could be related to the NRF two pathway. So in other words, NRF, two super important, and now we're going to bring it into 2020. Right now, during a pandemic, how does this affect us? SoEric Rieger 9:25 that's a lot,Ken Brown 9:26 but it's that's what the whole episode was about before.Eric Rieger 9:28 Yeah, that was just the summary. So we just crammedKen Brown 9:30 a full hour into just there. So Alright, so now we ended the show with saying, Okay, this is your NRF two pathway, hopefully, you listen to it. If not just know that it's super important. You can keep listening to this, the NRF two pathway master regulator and will at least have some built in mechanisms to fight viruses that are going on. So I want to talk about two natural ways to keep your NRF two pathway in great shape. Okay, let's do it. All right. So first one. This is very very dear to me. This is why I like how everything starts coming together at some point. first topic sulforaphane, sulforaphane. I have talked about sulforaphane for years. Yes. All thanks to Rhonda Patrick and a YouTube video and her going on Joe Rogan and discussing it. I've gotten super into sulforaphane. It is one of my favorite topics. Briefly, sulforaphane. If you're a geek, and you want to really know what's going on is an isothiocyanate. And what this is, is the molecule that is found in cruciferous vegetables, broccoli, cauliflower, things like that. And when these cruciferous vegetables are in their sprouted form, meaning it's a little teenager, a juvenile, okay, a juvenile broccoli, they tend to have much higher amounts of these precursor of the precursor that our bodies can then make sulforaphane and we get in So this was actually really exciting discovered by doctors at Johns Hopkins in 1992. Since then, thousands of articles have been shown documented the beneficial effects of sulforaphane and they have shown 39 distinct health mechanisms including blocking inflammation, like we talked about promoting brain health, promoting anti aging, General glossy things, but there's so many studies on this. The problem is this. The precursor to sulforaphane is a molecule called Glucoraphanin Glucoraphanin and then become sulforaphane. When the broccoli sprout is chewed, it releases an enzyme called murasa kinase. So basically the broccoli sprout sitting with this molecule called Glucoraphanin. Okay, when you eat the broccoli sprout, you release this enzyme called murase kinase, which converts glucoraphanin to sulfur a thing. Easy enough right? So far, so Bottom line is we have known that the second that sulforaphane was discovered by Johns Hopkins, people have been chasing that idea because they're like, that's something that nobody else has tapped on.Eric Rieger 12:11 It sounds to me like what we're alluding to is a little bit of a stability issue probably long term and how to deliver this if someone isn't going to directly eat juvenile or adolescent broccoli sprouts, right?Ken Brown 12:24 Correct. So what has been shown by the Johns Hopkins people is that the amount of glucoraphanin which can actually be absorbed to then be converted, right, so now we're talking about just absorbing the glucoraphanin and then converting it is somewhere around two to 15%. Eric Rieger 12:41 Okay,Ken Brown 12:41 so extremely poor bio availability. And the biggest problem is that sulforaphane is extremely unstable. So you can't just get a bucket of sulforaphane and just put it there. Yeah. So if you go to Amazon, and I've done this, because when I was looking at sulforaphane got super excited until I started listening to a bunch of other doctors describe all this in scientists, you're gonna find a ton of products out there that say broccoli sprout extract, or they're gonna say sulforaphane. You read the label, it says gluco raffin. Right. Some of them will throw in murasenase and so on. And Johns Hopkins did testing on a lot of these. And Surprise, surprise, most of them did not have even glucoraphanin, let alone sulforaphane. So they came to the conclusion that it's really, really difficult. And we've got these products that are out there, but probably people are wasting their money on most of theseEric Rieger 13:36 breaking this down. Isn't it possible that maybe even some of those companies that wanted to have the rossin Ace and the gluco would have always butchered Ken Brown 13:45 glucoraphaninEric Rieger 13:46 glucoraphanin. If they wanted to have those available in a delivery system, the instability of these delicate molecules, even if it was tested and shown, it wasn't there, it's probably already changed. It's probably just not stable enough to survive the packaging. Ken Brown 14:01 Correct. And so even these guys even went so far as to say, Okay, well, maybe the rate maybe they're trying their best maybe they're raising the broccoli sprouts and then they started looking into the broccoli seed business. Eric Rieger 14:11 Oh, okayKen Brown 14:12 oh yeah super cool on this one also. So, Rhonda Patrick goes on a YouTube video and describes all this and says you need to make your own broccoli sprouts. So everybody ran out and started doing this. Awesome. I've even done it myself. Try to do it. And then you find out that Oh, a lot of broccoli seeds that are out there. Don't even have any. They're even not broccoli seeds. They're actually like alfalfa, sprout seeds and really cheap ones. So it comes into that whole thing again, one more time, the supplement industry when you talk about this, unless you're doing third party testing, and looking at that there's a high likelihood that what you're taking is a marketing ploy.Eric Rieger 14:47 That's unfortunate.Ken Brown 14:48 Yes, super unfortunate.Eric Rieger 14:50 It's wastes a lot of people's time. They're trying to get healthy and they're given the wrong thing. Yeah. Now what we want to do here,Ken Brown 14:55 all right, so this is what gets really exciting. So now really cool. So all of this has been going on up until 2017. So there happens to be one stable sulforaphane product in France called prostu Fein. It is considered a drug and it is used to treat prostate cancer. Right? So in 2017 the only real way to get sulforaphane was to eat broccoli sprouts. Now we have a mutual friend David Roberts, who unfortunately, he is extremely intelligent man with very close ties, but his wife Maura got breast cancer, Eric Rieger 15:29 yes.Ken Brown 15:30 And so he took her breast cancer cells took it to his good friend john Gill day and I won't get into the story of this because we're going to have them on as guests right? So I'm just gonna say briefly, why this got developed. It was developed in the most altruistic and cool way they took her breast cancer cells, and they realized that what natural molecules could actually help curtail the cancer, what could kill the cancer and one of the molecules they found was sulforaphane, right? So then it was that's great. So David went out and did the same thing that I would have done he bought a bunch of them. And then since he has the capabilities, he tested them and found out that none of them had sulforaphane. Right. So his good friend, PhD, john Gill day, figured out a way to make the world's only stable and bio available sulforaphane product, which is on the market. And in fact, they have shown through third party testing, that is exactly what they say. They have done this with every single batch and they have the ability to check. This is what I love about this. They have the ability to check on themselves on coworkers on anybody that will come in what the effect was in the bioavailability was and so john, when we met with him, he said, Oh, no, we were checking the dosing, I would just check to see what my NRF two level was. And it would go up within an hour which shows the bioavailability of this. It's doing what you wanted it to do. And what's so cool about this is that it isn't like oh, I took it. It isn't like caffeine where you take it and get an hour's worth of bite. Hit. They showed that when you turn this on, it stays on. Eric Rieger 17:03 Yes. Ken Brown 17:03 So what it's like a sinusoidal type wave where you're going to keep this thing going as long as you start supplementing, so that was amazing. And then they started looking at individual markers. So when we talked to john, we said, well, what else have you guys looked at? He's like, Oh, we looked at interleukin six. interleukin six is one of the cytokines which starts the cytokine storm in COVID-19. is like it actively decreases this and we checked it in many different ways. It lowers something called NF Kappa b. Nf. Kappa b is the start of the inflammatory process by controlling that you don't allow a cytokine storm to happen. Obviously, they're looking at things which are related to inflammation. Sure, and then he threw out one little curveball there he's like, Oh, did I ever tell you that it increased BDNF, brain derived neurotrophic factor another dear to my heart molecule,Eric Rieger 17:51 definitely neuroplasticity, Ken Brown 17:53 neuroplasticity, and they were able to measure the rise in NRF2 directly at different dosing at different times. So the science is just absolutely beautiful. And then if you start looking at sulforaphane regarding COVID-19 It is well known that sulforaphane, specifically down regulates the docking protein called tmprss two, regardless, the docking protease because right now we're talking protease inhibitors, right? What sulforaphane has actually been shown to do in vitro definitely in vitro is that it can actually prevent if the virus sees the h2 receptor, and it comes here, it has to get close. And then it needs this thing called the TMPRSS to to actually touch the virus and then dock it to the h2 receptor. It Down regulates that.Eric Rieger 18:53 So it gives the virus less opportunity to infect the cell.Ken Brown 18:58 It gives the virus less ability to Land, right? It's just like the virus is going around doing this. So keep that in mind because it's super cool. So when the NRF two pathway is on, then you have all aspects of your innate immune health, meaning your immune system starts paying very close attention. So if you have an invader, it knows what to do immediately. So it increases your immune health. It mitigates the cytokine storm by decreasing aisle six, NF Kappa beta and all these other things, right? And that's how you end up protecting your organs. That's how the when the NRF two pathway goes up, this is so cool. So the NRF two pathway sees it and goes, wait a minute, this virus is attaching to the h2 receptor. Everybody downregulate h2. I mean, you want to talk about like a cool sci fi movie. Yeah, go down, follow the NRF two pathway into the cell. It's almost like the Star Wars style where it's like they're actually we are being invaded. We have got tie fighters coming in. They are all able to enter through the h2 receptor downregulate, always to receptors.Eric Rieger 20:05 So part of the problem of getting sick is when a bunch of cells, they encounter a pathogen quickly, right? And they all become inflamed far quicker than the body can effectively respond, right? That's when things kind of spiral out of control. Correct. So I could I could if we could all picture like the new Dallas Cowboys Stadium, we call it new, because it's 10 years old now. But all 100,000 people want to go inside. They all need to get inside, they all have a ticket. They're ready to go inside. But suddenly, let's just pretend that the stadium is the cell and all of the people come in to watch the game happened to be the virus. Suddenly, the Cowboys say, No, no, no, all of these people might get sick. Let's shut down all of the gates to maybe one or two. And now if you had to funnel all 100,000 people, not from the 60 gates that are all around but just through one or two doors. That's downregulation that's what What our cells are doing in NRF? Two is taking away the availability for that that virus to get into the cell.Ken Brown 21:06 Yes, that's exactly it. So now imagine you're in a stadium, and you've got 10 entrances, and there's 100,000 people trying to come in. And the stadium happens to be somebody that the stadium does not have a properly functioning NRF two pathway, which means before the game even happened, the stadium probably is bloated and obese. Sure, with some hypertension, sure. I don't know stadiums could do that. And then this one does. And then so what ends up happening is instead of having just 10 designated entrances, yeah, they've just got holes everywhere everywhere.Eric Rieger 21:39 There's no one's taking tickets,Ken Brown 21:39 no one's taking tickets you just walk in whenever you want. That's what it is. And that's why when people have unregulated amount of h2 receptors, then that's how you can end up getting so sick so quickly, so fast. So your I love your analogy. The first episode was cutting the the phone line to a bank and this one is football. I don't really know how your mind works, but that's just allEric Rieger 22:01 I don't know either. No one knows how this mind worksKen Brown 22:04 I'm so getting, you know, kind of like I mentioned we're gonna have David and Jonathan we're gonna let them really geek out about this Eric Rieger 22:11 Great guys tooKen Brown 22:11 Great guys but the bottom line is that is not sulforaphane is just a molecule that I love. They developed a product called Brock elite BROCELITE which I need to talk to them about that because I recommend it to so many of my patients, and especially when I'm doing telemedicine visits, I say I really need you to just pick up some BROCELITE we need to do this. And without fail, they'll be like okay, Dr. Brown told me to get this broccoli How much do I do? And I'm like no, it's Brock elite. I need to talk to those guys but Brock pause elite Yeah. So but we're gonna have them on to talk about that. So what I love about this show, Eric is that we do these shows and I just start going down these rabbit holes but I'm I'm a better doctor because of it. I learn a lot more because of this. Angie sends me just by Get some buckets of articles. And so I can go through this. So it just got me thinking, like, wait a minute, whenever we talked about the NRF two pathway, whenever anybody's ever talked about it, it's always sulforaphane.Eric Rieger 23:13 Is there anything else that could help that NRF two pathway?Ken Brown 23:17 I'm really glad you asked. Because if you didn't, then I'd have nothing else to talk about. Eric Rieger 23:21 Yeah, we can talk about golf, because you teed it up.Ken Brown 23:27 Alright, so no more dad jokes. All right, so, um, and so every single show we learn more and more with this, but then I started going down the NRF two pathway and working backwards and deconstructing this, found this incredible article that talked about and this is the actual title of the article published just last month, the potent anti viral effects of the NRF two pathway and how to naturally raise it using polyphenolic compounds. Eric Rieger 23:55 Okay.Ken Brown 23:56 All right. So what this article showed is that they first and we've done discuss this on the show. They looked at the potent antiviral effects of polyphenols. They looked at compounds like quercetin and green tea extract. Specifically, they wanted to know that although these polyphenols we've shown multiple times do amazing things to mitigate your immune system. They too are anti aging molecules. And they actually are potent antioxidants. They said, Well, what if some of the benefit of polyphenols is actually due to the NRF two pathway?Eric Rieger 24:27 That's interesting.Ken Brown 24:29 Yeah. Interesting. I'm over here. Everyone's looking at sulforaphane. And these guys are like, well wait a minute, which we just got done describing anti aging effects, anti blah, blah, blah, of the NRF two pathway. And what if some of the benefits that we're seeing with these other molecules like polyphenols, right can actually increase the NRF two pathway so these guys looked specifically at that. What they wanted to know is if these polyphenols can increase the NRF two pathway, which will help fight COVID-19 bold statement, love these guys. It's huge. What these researchers were able to show is that these polyphenols can increase the NRF two pathway by blocking the keep one repressor protein. In other words, they allow they get the Think of it this way your NRF two is tied up by a security guard by I don't know, your your the analogy guy, what would it be here? Eric Rieger 25:29 It just seems like that this is now a second instance of where polyphenols have demonstrated that they run. They're blocking they're blocking for things to continue to happen beneficially, because it also blocks that that particular enzyme that breaks down CBD and or I'm sorry, Nandamind, right. Ken Brown 25:52 Oh, Eric Rieger 25:52 and so if we're blocking there, we're also blocking this.Ken Brown 25:56 Oh,Eric Rieger 25:56 this little guy here. Keep one.Ken Brown 25:58 Oh, so cool. I'm glad that you made that leap so quickly. Your mental agility sometimes just impresses me, and just just sports sports analogies. Alright, so I'll say this again, these guys looked at it and they said it does definitely raise the NRF to pathway. We believe it does it in a different way that sulforaphane does. So for fame directly releases NRF two through this crazy biochemical wave. And definitely it is the most effective way to turn on the NRF two pathway. sulforaphane, but these guys showed, hey, when you add polyphenols to it, they take care of the security guard that's holding on to your NRF two and they go, Hey, come here, and they hug they hug the security guard. And so it allows the NRF to to get free, hop in the cell and turn on 250 genes. That's right. When you're under stress, chronic stress, you have more security guards you have more keep one, the more inflammation you have when it Hips, the scale, a little bit of inflammation turns on your NRF to too much inflammation. And for whatever reason the keep one doesn't let the NRF two out. So you spiral downhill quickly.Eric Rieger 27:11 Interesting. It's almost like a medical term. It's called a negative feedback loop. It's almost enhancing the bad effect, almost enhancing the bad effects.Ken Brown 27:20 And in addition to the antioxidant properties that they showed with the polyphenols, by keeping the reactive oxygen species lower, that negative feedback loop doesn't happen because the keep one protein doesn't realize that there's chaos going on. So in other words, the polyphenols go, Hey, come here, go ahead and give me a hug. And then the other polyphenols go clean up the mess, clean up the mess. So this guy doesn't get all eager and be like this over aggressive bouncers, security guards. Eric Rieger 27:48 What a great compliment though, so now we not only know how to enhance the activity of the NRF two, but now we also know how can we allow the NRF two wants the pathways activated to do its job. Better. Oh yes.Ken Brown 28:01 So if you haven't put it together yet, I'm giving you a secret recipe on how to turn on your NRF two. So once the NRF two is turned on, it'll maximize the effectiveness. And especially when the polyphenols are around and they take care of the antioxidants, the NRF two doesn't have to worry about that. And it turns on more cells saying just go down. Let's let's get all these cells in line, let's really ramp it up, we are ready to do battle. So in conclusion, what they said was the author said that we should be taking certain polyphenols to work as both a direct antiviral, a direct anti inflammatory, and for the first time ever written in literature directly increased the NRF two pathway. That's amazing. It's the first time I've ever come across this. Ultimately, the authors are quoted as saying these results may provide a new method for discovering NRF two activation.Eric Rieger 28:57 It's just it's quite impressive because we we are feel like we're pressed for information right now because we're living in a pandemic. And we're all trying to find our ways to return to normal. But this stuff doesn't end with the pandemic. This is this is protecting your health and your life and the cells from over inflammation. Anyhow, it just so happens that they're saying, keep this system in your body enhanced, it still works for you do these things. It's still here to protect you.Ken Brown 29:23 Absolutely. So that was one incredible article. So kudos to those authors. They said, Hey, does does the NRF two pathway help with COVID? Yes. Oh, what are other things that we can do to take this? because very few people even understand that brocelite exists, right? So you've got all these people buying broccoli sprout extracts, which is doing nothing. And now they're saying okay, since now we've got this ability to have a stable so for pain and now we have this ability to have this polyphenol which can actually help free up the NRF too. So it got me thinking, is anyone else looking into this? And as it turns out, I found another super cool publication. Specifically on I'm gonna love this olive oil and wine polyphenols. And it's modulation of the NRF two pathway. That's nice. That's good. That is awesome because these guys showed significant increase in the NRF two activity from the polyphenols in olive oil and in wine. These are the polyphenols that that we work with because they're large, stable polyphenols. The first article was looking at smaller phonology compounds, meaning they're looking at very little small branches, coarse attends a small branch of a larger polyphenols, right, and green tea extract. ecgc is a smaller branch of this large green tea molecule. These guys said, Hey, you know what? We're seeing the same thing. The conclusion is that it's not just the antioxidant effects of these polyphenols that make them incredible, but it's the ability to turn on the NRF two pathway is a novel and new concept that needs to be further investigated. I kind of feel like we're saying stuff. Like, I don't think other people reading these articles because this is nuts what I just said, I just said that large stable polyphenols can turn on your NRF two pathway. Nobody has ever said anything like that to me.Eric Rieger 31:15 No, I haven't heard that either. But it made me think of something though. We talked about what constitutes a high level CBD source. And one of the things that we've that we've not only talked about, but we've seen clinically, is that full spectrum. CBD tends to be the best method. This is almost like we're endorsing a natural full spectrum, polyphenol source.Ken Brown 31:39 Ooh, we're gonna get to that. All right. So now at this point, I'm just like, there's no way I'm preparing for this show. I could stop right here and say this is the mic drop, pow. There it is. But I'm like, No, no, there's when you start going down these rabbit holes of research. Then you start looking at the references that other people do and then you start looking at the author's and then Andrew will be like, you're not going to believe it. Check this out. Then she sends me this one, that she found an article looking at alcohol induced liver damage in mice. And if improving the NRF two pathway will help attenuate that. Now this one is relevant. It's relevant for this discussion because although it's not about COVID, these authors are looking at improving the NRF two pathway to improve a chronic disease, alcoholic liver disease. So what these researchers did is they did the same thing that most researchers do when they look at polyphenols they looked at using curcumin curcumin is a polyphenol well known and Baicalin and BAICALIN. Bruce Burnett, which is a PhD that has worked with us. That was one of the molecules he worked with. He's probably saying you're saying it wrong. Probably saying that. Sorry,Eric Rieger 32:49 sorry Bruce.Ken Brown 32:50 Yeah, baicalin. I don't know. Whatever. It's something. Those are two small polyphenols and what they showed is they were able to induce alcoholic liver injury tomorrow. And I don't know how they did it. I know what you're gonna say is, I don't know. I don't know what they like to drink. I don't know if it's tequila 512 probably tequila 512 the favorite, the favorite tequila of mice. So tequila five one to check it out. That's Eric's other company. So, what they did is they looked at this and they were shocked to see that each one of those increased or, number one, the mice that received the polyphenol compounds had protection against liver disease, from the alcohol, huge. Then they said, Well, is it the antioxidant effect? Or is it the NRF? Two, then they checked NRF two levels, and the ones that had the most protection had the highest rise of NRF. Two interest huge, then I'm so glad this researcher did this. What if we use both of them? Yeah, so the nine they combined, and guess what they saw better exponential growth of the NRF two, exponential decrease in inflammation and this comes back to something that you and I have talked about so many times, whole plant versus molecular pharmaceuticals.Eric Rieger 34:07 It's been we've seen it time and time again from from isolated pharmaceuticals, on and on and on. And now we're talking about really just small natural derivatives but still better in their larger state. Right.Ken Brown 34:18 That's exactly what it is. And so we have talked about this, that we have a very hard time beating Mother Nature. Yeah. And you know, and I realized that the pharmaceutical industry continually does this or they say that molecule does this, we can mass produce it. And I think that in many ways, it works extremely well. And in other ways, I think that we have we're just not smart enough to do this. This is a great example. So I'm gonna throw out a concept here that I don't think a whole lot of scientists are thinking enough about this. The whole plant or the large stable poly phenol. So the large stable poly phenol, knowing that this other study looked at two smaller polyphenols, they said hey, what if we put them both together? Hey, there, we have that look. A study that looked at Whole olive oil polyphenols, which contains many of them whole wine polyphenols, which had tremendous increase in the NRF. Two. So we've got a friend, Sylvia, who's a PhD in Spain. And she published in her thesis, this incredible article where it looked at large table polyphenols like to borracho and then chestnut, to bracha and chestnut. And then she showed what happens when it becomes digested. And then she took those same polyphenols and she put them in a, I guess, a theoretical microbiome. She fermented them, right allowed bacteria to do this. And then she did a mass spectrometry. I'm saying that right about the molecules produced. And it's really cool because guess what happens when they have a large stable polyphenols, you end up producing ecgc which is green tea extract, you end up kicking off course at the end, you end up kicking off these larger tannins which then get broken down in other words, give yourself body, the largest template, let your body decide what it wants to do with it. And so that's kind of my take on this. So kind of kind of thrilling. I think the future of this research is going to be large, stable polyphenols, let your body do what it wants. And it's going to increase the NRF two pathway.Eric Rieger 36:18 I think that's awesome. And it makes sense. And it just so happens to continually fall in line where Mother Nature knows the answer. They know she knows the way.Ken Brown 36:27 So here we are, we know that the NRF two pathway is the master regulator and probably one of the major defenses against COVID-19. And we are slowly meeting a whole lot of very influential, important people in this field and one of them is friends with Dr. Fauci. And you said, Man, we need Fauci on here, I want to pin them down and be like, Why? Why aren't you talking about the NRF two pathway or something like that? Just you know? Just why aren't we talking about IVFEric Rieger 37:00 idea. It's unfortunate that it took until the last year and a half for us to have these kinds of discussions. Yeah, I mean, but it's it's technically a relatively new discovery compared to other things that everyone's more familiar with. However, I think it's a critical discovery on how we control disease going forward.Ken Brown 37:19 Yeah, right. And you've probably looked at me like why did you just throw in that weird sort of Southern accent like you don't really in what I like to do around much smarter people is just really hit the I just want to just act like I know absolutely nothing, so I don't have to live up to anything. Yeah, so if Fauci ever came here. I'd be like, wait, why aren't you talking about the NRF pathway? He's like, What in the world? This guy's a doctor.Eric Rieger 37:40 Yeah, it's interesting how you turn into ross perot.Ken Brown 37:44 Alright, so anyways, we know the NRF two pathway is a master regulator. It may significantly help fight COVID-19 sulforaphane directly stimulates NRF two polyphenols stimulate NRF to buy in. I didn't Spoiler alert, where you're going there, blocking the inhibitor protein called keep one. Then I went into more detail because I just went down a quick rabbit hole. Guess what else it does was that it up regulates the keep one esterase enzyme that breaks it down. Okay? So just like when you brought up FAAH Yeah. Where polyphenols decrease that this one increases that. Like it's crazy how smart Mother Nature is just crazy. So bottom line is we've got sulforaphane, which directly stimulates NRF two pathway, we've got polyphenols which decrease the inflammatory pathway, same, same sulfur thing. But the polyphenol goes oh look there. So first thing, I'm going to tie up the security guard and let sulforaphane do its job and allow the NRF to to go up. In other words, my question is this. What is my NRF two levels I would love to call up john Gill day Say, let's check mine because nobody's done a study. I just showed two three different studies on polyphenols. Nobody has shown a study on what if a guy like me who's been taking regularly atrantil which is stable polyphenols, and I take brocelite, which is a stable sulforaphane. What is my NRF? Two level? Pretty excited to see what that would be? Because theoretically, I'm, I'm, I've got it ramped up.Eric Rieger 39:30 What a crazy concept. It kind of made me think of something like an application, you made the reference to the protection of the liver. Right? And for people who have alcoholic induced hepatic issues, so what if, and I'm just throwing this out there, college kids, for instance, what if part of a wellness check was to keep tabs on a college kids in our future? pathway knowing that they if they've already admitted they probably consume alcohol, but you're giving them a barometer saying, look, I, we know that you're young and you're doing this partying, but you need to make certain that you are having this level of protection. Because it seems like a lot of a lot of people understand to protect your liver. Don't don't consume too much Tylenol, for instance. Well, knowing that whatever in your back pocket you also knew, okay, yes, I do hang out with friends, right? enjoy an occasional drink every now and then it may actually consume a little too much. But I need to know that I'm giving my body the defense's, it's necessary to protect my liver that maybe it'd be interesting to use a test like that and make it where it was just the same as checking blood pressure.Ken Brown 40:41 Oh, I mean, I like where you going with it. But I'm just going to take you to a grander scale right now. Everybody's going back to college. Wouldn't it be amazing if we had some sort of rapid NRF to test and it's like, hey, look, your NRF two is really low. Yeah, I Why don't we Why don't you or before you come to Why don't you Why don't we work on getting that up because you will stand a better chance of not having a significant bad outcome if you were to get exposed to source code toEric Rieger 41:10 say it's like a pandemic seatbelt almost it's almost like it's it's it's your it's your shield to go back out into the world and give yourself the best protection possible in addition to the mask.Ken Brown 41:21 Oh, speaking of best protection, pross possible you were hinting towards the FAAH, FAAH? Ah, we've done a whole podcast on that. That is the enzyme that breaks down your body's own inanda mind right, we can get into that so Oh, yes. found an article went down another rabbit hole now. Yeah, as it turns out, an annamite into ag guess what they do, they turn on the NRF two pathway.Eric Rieger 41:43 So we want thatKen Brown 41:44 we want that. So you need a properly functioning endocannabinoid system. You need some polyphenols to help the sulforaphane do it. I mean, if you were to take theoretically, if you took it Broccoli, and KBMD health CBD. It's almost like a great bio hack.Eric Rieger 42:08 It's not like a great bio hack. I think it is one. I mean, it is anecdotal but everyone I know that takes those almost daily doesn't have COVIDKen Brown 42:23 to truly truly anecdotal but now all that being said, I mean think about this. So just to sort of recap this the first episode was about how important the NRF two pathway is. And it is super important and we get into the science of it. This one specifically discusses natural products which even if they didn't affect the NRF two pathway are extremely beneficial for you they're extremely or other anti aging anti inflammatory antioxidant we can get into the the polyphenol aspect of how it improves health performance. He increases nitric oxide. Oh no time on this one here but yeah found some articles how certain polyphenols increase BDNF in other words all polyphenols that are checked increase BDNF, BDNF we're going to do a whole episode on that because that's another one of my favorite things to talk about that is something to improve everything's about brain gut to me in everything is burned out if you protect the gut, you protect the brain. And you know, we're going to have a you know,Eric Rieger 43:24 it should do and we were we've been pretty good about doing this but yes, we do. We do know quite a bit about artron to broccoli and KBMD CBD, but to be fair sources of getting sulforaphane obviously, just like he said, natural real broccoli sprouts, right. The next thing for polyphenols you can get it from fresh fruits and fresh vegetables, polyphenols are those really colorful or the things that make your fruit really, really colorful, and then of course, a reputable CBD. So what I'm saying here is even if you don't use any of the stuff, take that knowledge, find those to supplement your diet daily so that you can arm yourself and be safe. If you can't find one of these for some crazy reason, if you're listening this you should be able to but if you can't find the foods that Mother Nature is providing us all with. And really what we're trying to do is make certain that you're getting your daily dose of all three of those things. Yeah,Ken Brown 44:19 so if you're sitting there if you have a rainbow light plate, and some sprouts, by the way, sprouts are super easy to grow. This is so if you're not into supplements, you're into the food. A lot of people have great evidence. A lot of people have great tutorial videos of how to make it. I've done it, it's super easy. You just have to make sure that you get the right seed. If you go to the Brocelite.com website. They actually have seeds that they have tested. So they can tell you which brands if you want to get to this kind of a fun thing to do. You got to cut them at around nine days I believe. And that's where it's at because of my lifestyle. I try to eat a healthy diet, but I also understand science like this. So Ah, augmented a little bit. And I try and just push the needle in a healthy direction by taking certain supplements. And the supplements that I take on a regular basis are polyphenols, atrantil, and broccoli, and a few other things that we've discussed on the show to help for viral illnesses, illnesses and such. So the cool thing is that everything that we're describing, about five or six months from now, somebody else will talk about, and then it'll be novel. Yeah. Is it the same thing that happened early on with when I went on wellness Mama, and we were talking about all that stuff? And it was so novel. Yeah, cuz I was like, Oh my gosh, I feel like I'm saying stuff that nobody else is talking about. I'm gonna be this pariah. But I'm standing behind the science and just, it's all about science. I'm not saying Atrantil to Brocelite or KBMD CBD does anything. What I'm saying is the molecules of sulforaphane and poly phenol have been shown to increase the NRF two pathway. That's what I'm saying. What does the NRF two pathway do? Whole lot watch the last episode that we did.Eric Rieger 46:02 Yeah, I mean COVID file number nine. incredibly important, and honestly, probably we should revisit it post pandemic and just dig even deeper into NRF. Two.Ken Brown 46:11 I wish we had deeper pockets so that we can just go to certain like right now with all these students going to college we could just show up and be like, well, this college all got Broc, they'll get the biohack combo. AndEric Rieger 46:23 I'll just compare like a large scale campus justKen Brown 46:26 yet just because right now we're seeing all these kids go back to college and they're being sent back home UNC Notre Dame saying that it's anybody back but they're making them basically do the, you know, dorm schooling at Texas Tech, I just wrote a check. So if you want to offset some of that, just by asking us to participate in that, that'd be really cool. I just had a student or I just had a patient that goes to tech today and she said that they had a bunch of cases. So she's not going back Texas Tech is gonna have to every school is gonna have to do this. They're gonna have to play this game.Eric Rieger 46:56 Wow. Yeah, it's gonna be kind of wild. Hopefully we can just do what we can to give, give ourselves and our family the best opportunity to not get sick.Ken Brown 47:07 So recap this episode for us, Eric.Eric Rieger 47:12 Number one, watch episode number nine. Number two, we need our n NRF two pathway to be fully functioning and healthy, just like we talked about ECS hundreds of times, in order for us to be in the best position possible to fight off disease, specifically things similar to COVID-19. And essentially, with a highly functioning NRF two pathway, we can stave off that disease, we can decrease the inflammation and we can actually shut down the ability for things like COVID-19 to make its way to infect our cells. In addition to that, in order for the NRF two pathway to work well. You have to make the conscious decision to take either the supplements or the correct foods to arm your body to give it the tools to make that an Our f2 pathway work. Yeah, really what we said,Ken Brown 48:02 we're going to be talking to different guests, we're going to be talking to Dr. Tom O'Brien about different diets to protect your gut to protect your brain. What I really like is that our messages is not new. It's not unique, and people are starting to starting to realize it.Eric Rieger 48:16 Yeah, definitely.Ken Brown 48:17 So, alright, so part one and RF two, part two. Oh, boy, we've got Natural Ways to Increase your NRF to new to me super excited that I have this information now. And I hope it's exciting for you all. I think it's really important that everyone should share this, please, that we're getting into some very scientific I get that I get it can be a little difficult to listen to, but the gist of it is you need your NRF to improved to lead a very healthy life, you stand a better chance of undergoing some sort of insult including a viral insult. Your body will deal with it better if you have a proper functioning NRF two, so like, share, get this out there.Eric Rieger 48:58 Wait the way you kind of just said that. Maybe You think of this, we can't sit here and tell you that they a fully functioning NRF two pathway augmented by poly phenol. So if your veins and CBD is necessarily going to stave off all your disease, but I can tell you quite confidently that if you don't have a well functioning enough to pathway, your chance of being really really sick when you're exposed is probably significant.Ken Brown 49:22 Yeah, and it's significant and if you don't have a functioning NRF two pathway, then your chances of becoming diabetic becoming hypertensive becoming obese, developing cancer, although they definitely do.Eric Rieger 49:33 So.Ken Brown 49:34 Awesome. Well, I'm glad that we close this out. Now you have different ways to increase your NRF. To read more about this look at the polyphenols and ultra until these are the stable large polyphenols that we talked about. Look at the science behind Brocelite. That is the world's only stable bioavailable sulforaphane, which we know that we trust these guys. They do third party testing they do everything that we do with atrantil. So that's how come we become Good friends with them and hope to continue to utilize their science they can utilize ours we can help each other we're going to augment everythingEric Rieger 50:07 Raka lead also has a professional version which is only available if there is a physician on board and it just so happens that at KBMD health this guy is the KB and the KBMD. He is authorized to distribute the professional version of Brocelite. So if you go to KBMD health.com go to the store, you'll find everything that Dr. Brown has laid out available as a supplement to help you build up your NRF two as well as your ECS at KBMD health.Ken Brown 50:36 Yeah, and the broccoli plus they're smart guys, they actually have another isothiocyanate in there that they figured out helps absorb and they threw in curcumin, polyphenol, right so like when when john hears this, he's just like I've been talking about this for 10 years.Eric Rieger 50:53 Thank you, john.Ken Brown 50:55 But that's awesome. Everybody, take care stay safe and yet like share Just get this word out. We, our biggest thing is if we can help one person if we can. I hear it from my patients all the time. Like I feel way better. I'm like, that's awesome. I love it. AbsolutelyEric Rieger 51:10 like and share. That's it. That's gonna do it for COVID number 10. And, well, sorry for the break between also nine and 10. Lots of information. He really was on call last week for the hospital. So when we broke, it just happened to be at that point in time. Anyhow, we'll we'll see y'all next time around.Ken Brown 51:27 We're good. We're good. Everybody. Stay safe. Much love. Get your sleep, eat well.Eric Rieger 51:32 Oh, yeah, sorry about the weird offset here. Again, we're in the studio by ourselves. So obviously, it looks kind of odd to me just kind of off the side, rock and fade in and out. But we'll be back next time.Ken Brown 51:41 Well, fortunately, if you're watching this on YouTube, what you will see is what looks like a mane of hair coming into the picture and then eventually a face joins because Eric has yet to have a COVID haircut. Now I'm not going toEric Rieger 51:53 wait to see what happens.Ken Brown 51:55 All right, everybody. Take care.Transcribed by https://otter.ai

Ep 55- Dr. Ken Brown- Beat Bloating and Improve Your Bones

Happy Bones, Happy Life

Play Episode Listen Later Aug 18, 2020 53:16

“If inflammation and the presence of reactive oxidative species can turn on a disease process like osteoporosis, it can turn on different processes like Alzheimer’s, dementia, and autoimmune disease.” - Ken Brown, MD Dr. Ken Brown received his medical degree from the University of Nebraska Medical School, and completed his fellowship in gastroenterology in San Antonio, Texas. He is a board certified gastroenterologist and has been in practice for over 15 years with a clinical focus on inflammatory bowel disease and irritable bowel syndrome. Dr. Brown declared that his mission is to bridge the gap between medical & natural science. For over a decade he has been conducting clinical research for various pharmacologic companies. Dr. Brown recognized an unmet need for something natural that could help his IBS patients find real relief. After developing the only all-natural & clinically proven answer for IBS & bloating for over 6 years, ATRANTIL (ahh-tron-teel) launched in the summer of 2015. Dr. Brown developed Atrantil to help those suffering from the symptoms of IBS which we now know are caused by bacterial overgrowth. In today’s episode we delve into the causes of bloating and IBS and what can be done. We also discuss how we can reduce inflammation and improve our bone and overall health with Atrantil. Links Affiliate Disclosure* Get Atrantil here! Timestamps [00:35] Introduction [05:39] The origins of Atrantil [10:23] Gas, bloating, and polyphenols [19:55] Atrantil as a post-biotic [26:40] What actually is IBS? [31:52] SIBO and testing [33:15] Who should avoid Atrantil? [39:38] Polyphenols and osteoporosis DISCLAIMER – The information presented on this podcast should not be construed as medical advice. It is not intended to replace consultation with your physician or healthcare provider. The ideas shared on this podcast are the expressed opinions of the guests and do not always reflect those of Margie Bissinger and the Happy Bones, Happy Life program. *In compliance with the FTC guidelines, please assume the following about links on this site: Some of the links going to products are affiliate links of which I receive a small commission from sales of certain items, but the price is the same for you (sometimes, I even get to share a unique discount with you). If I post an affiliate link to a product, it is something that I personally use, support and would recommend. I personally vet each and every product. My first priority is providing valuable information and resources to help you create positive changes in your health and bring more happiness into your life. I will only ever link to products or resources (affiliate or otherwise) that fit within this purpose.

Functional Nutrition with Gabrielle Grandell

Play Episode Listen Later Jul 2, 2020 57:18

Welcome, everybody, KBMD health family and gut check project fans. We are back now with episode number 37. And we have an incredible guest. This is Gabrielle Grandell. She's gonna be joining us here in two minutes. But of course, this is the gut check project with your host, Dr. Ken Brown. Can you want to introduce Gabrielle for us?Yeah, absolutely. I'm so excited about this. We were introduced through a mutual friend Gabrielle Grandell. She is currently practicing at living well Dallas, a certified health coach certified in functional med as well. And she calls herself an integrative dietitian. Why am I so excited about this because I would love to be sending her people like all day long. This is so cool. And my goal is that she has enough fun that she's a recurring guest slash co co host, because I think she's gonna really elevate all of our games and fill in a lot of gaps that that I need some education on because even though I got a degree in gastroenterology, we do about this much nutrition and I'm learning about it a ton. So thank you so much for joining Gabrielle.Hi, everybody. Glad to be here. Thank you guys for having me on. Looking forward to chatting today.Definitely. So Gabrielle, you are at living well Dallas, correct?That is correct.So tell us a little bit about what it is you do at living well Dallas because I have a feeling that with your experience, something that Ken and I've talked about is how we see there is a stark difference between our allopathic ideas behind nutrition and the approaches to nutrition. But really, there's this whole other world that's really started to gain steam, even though it's been around for a few decades. And that's the functional medicine approach to nutrition and how to help out with patients who have some some pretty hairy questions. So kind of tell us a little bit about living well Dallas and what you do there.Yeah, thank you. So living well Dallas is the first Functional Medicine Center in Dallas. Oops, I hit some thing here on my screen.It's okay. We all, sometimes we always do things.So it's the first Functional Medicine Center in Dallas. And so functional medicine, right is is about thinking about the medicine sort of why. Why are things happening? Why? Why are these symptoms talking to us? And not just what is going on? But why is it happening and what can we do about it? And so functional medicine is, that's, you know, there's lots of different providers in the center that offer help and treating the whole person because it might be different, different things that they're dealing with, that they need support in. But where I come in is helping people with showing them how nutrition and what they're eating, their lifestyle, their environment, how all of that is helping or hurting them. And so most of the time, what's going on with these folks, whether it be digestive concerns, or headaches or hormonal issues or blood sugar dysregulation, we see all different kinds of people. But the different symptoms that they're experiencing, are usually as a result of what they're putting in their body and what they're putting around them, right, which is nutrition and lifestyle and you know environment. So I help people we have when they when people come in, they fill out a good deal of paperwork, which gives us a really good understanding of their history, kind of their goals, their readiness, we have a readiness assessment, which is really nice to try to gauge where people are coming from in terms of if they're ready to change their diet or their exercise or their sleep patterns or whatnot. We have them fill those things out. That gives me a good understanding of how they came to us and what they're ready to do what their diet history is like. Again, their environment, relationships, things like that purpose. And so we have them fill those things out. And then I'm going to go through that with them in their first visit. And we're going to talk about all the different ways that their body is speaking to them. What has worked before, what hasn't. One of the main differences, I think, between allopathic and functional for what I do is the amount of time that I'm spending with people. So before I was at the center, one of my other positions was at the hospital doing Clinical Nutrition and seeing, you know, 25 to 30 people in a short period of time, all over the hospital,Which so you were in a major hospitalBUMC at Baylor University Medical Center. Yeah, in Dallas, whichSo, I love this. So you went and the reason why is Eric's heard me complain about this. And I've talked to my patients about this. Whenever I do hospital work, I am just absolutely shocked at how many bad things we do to patients. Like, let's not let them sleep, let's check their blood glucose at 2am. And no results. Let's do vitals just so that we can check a box. And then somebody that's in the cardiac rehab unit, they're eating their cardiac diet, which consists of pancakes, syrup, you know. But, it's low fat!Oh, it's just as long as it's low fat. Yeah, exactly. So that's awesome. I did not know that you did that. This is this is fantastic. Okay, keep going. I didn't mean to interrupt, but that is that that shift of being a nutritionist in a hospital system to doing what you're doing is you cannot get more polar opposite.And Gabrielle before you have to go too deep on on why I completely feel like the association for what Ken's looking for for his patients. And then what it is that you provide the audience may or may not realize that allopathic medicine itself is just traditional medicine as we view it today. And even though the word itself means scientifically based, I think that what has really appealed to Ken and me and others, like, like all three of us is that functional medicine has not forgotten the ideas behind applying new science to improve upon old methods. And the intake that you're talking about, traditionally, 15 years ago, there wasn't always a nutritionist who was experienced that took the time to one on one walk a patient through what's affecting them generally. I'm sorry, specifically, they were more general in approach.Very yeah, nothing was was individualized. And you know, I think that I don't think there should be really a monopoly on who can provide health information and who can help people right...their their husband but hopefully that changes as time goes on. So yeah, so doing the doing the intake paperwork and taking the time is very different than at the hospital where we'd see 25 or 30 people and we'd, you know, it's almost, you know, no disrespect, because I know that there's a lot of dietitians and there's a lot of people in the hospital that are making a difference and, you know, really helping out but it's almost like glorified lunch ladies, like we don't we're talking about calorie counting, we're talking about, you know, tube feed all this stuff is important, but what about the quality? You know, there, there's not enough emphasis on quality of food and again, an individualized approach. And so, so I think that's number one. One of the main differences is just the amount of time so it's like 90 minutes for a first visit. And then after that, which sounds like a lot, but really once you get the people talking and you know you are understanding what's going on And then you start talking about their, their goals and things. Time goes by really quick. I often, you know, struggle with keeping it to that time.You have...sorry, Eric really quick, just one of the best quotes I've heard in a long time. What I do is I find out what the symptoms are talking to my patients about you said the symptoms talk to us. Way different from my perspective, where you have a symptom, I treat it, it's saying something and we're ignoring what they're saying many times.Exactly. Yeah. And you know, if our hormones I'll just use as an example are talking to us as ladies around our cycle. It's not is the answer to take birth control pills, you know, and suppress that, or try to figure out what else maybe we can do to get things in balance in our in our lives, you know, and there's a lot of examples like that, I think,Well, I was going to say that there's also in addition to the client base focus, I would say that even in addition approach that a functional medicine or a functionally trained nutritionist is already approaching certain patient subsets differently than they did traditionally. Ken, the one I'm thinking about specifically how you talked about all of the most recent data that we know about what can make a heart disease patient, or someone more susceptible, and how the type of diet has changed over time how we care for them. Yet when we go into a hospital setting, or specifically what you saw, most recently, you you can't believe what there's sending somebody who's status post CABG, and it's all of the things that we wouldn't be feeding them anyway. It's it's in essence, a an inflammatory diet, and I was kind of curious Gabrielle do you find your training generally prepares you to handle either a neurology patient or a cardiology patient, different than the allopathic training?I think, right, I think over time what I've been learning, you know, because I've been blessed to really work alongside some pretty intelligent mentors. And you know, I've been blessed to go to conferences and learn from a lot of a lot of people. I think that what I was taught I've had to expand it quite a bit, you know, and sort of unlearn some of the things that I was was taught right. I mean, biochemistry is the same and things but but we I never realized how much influence big Ag and big food and pharma has on the dietetics industry,You know you're right there because the reality is that as as an allopathic physician, it seems like when I talk to my colleagues, unless in my field unless a drug rep shows up and hands them a detailed piece, there is no literature on that. But then when you go look at it, and you realize there's so much literature on this and then when we look back, my son and I were talking about About how we have our diets have changed, like over time as we evolved, and we have developed these different problems based on different food changes based on different things. And then you could see it track over hundreds of years of what's going on. I was just listening to a podcast on on breathwork and breathing and that kind of thing and about how so many of us have, you know, poor ability to breathe, and it's because of our anatomy is changed because of the food that we did. It just gets really complex. But the one thing that we have control over is what we put in our mouths. And, you know, we're telling people from at least in my perspective, when I see people I don't do this big intake thing like you do, but it is pretty funny every once in awhile walk into when we used to be able to see patients in the office and somebody will have a McDonald's cup right there. I'm like, yep, there's the problem. Don't even know who you are, what you're here for. I don't care. That's the problem right there.It's contributing for sure. Yeah,How in the world you go from the hospital and say I'm gonna make a complete change here and be a holistic or basically an integrative dietitian.Yeah. So it just wasn't as rewarding as I had anticipated it being you know, I felt it was, it was I was making a difference, which is part of why I chose to get into nutrition in the first place. I was making a difference with some of these people, but to your point, they their families, and you know, they bring back McDonald's and fast food to these people and the diabetes, you know, people they'd be in there the next month, and then the next month, and it's just anyway, so it became less where I felt like I was really making a difference and that anyone was really listening to anything about nutrition and it was such an emphasis on surgery and such an emphasis on medication and my role was very seemed more like data entry almost. And so I just wasn't making the difference with the clients because I didn't have enough time to help them out and really talk through them. And, you know, we get trumped by those other things in the hospital. And so it was a good experience. But I just started looking into just started reading and started looking found functional medicine and thought this is really interesting. This is really, they're really getting to the root of what's happening, which often is there's people's diets, you know, there's these other factors of course, but this is really cool. And so back when Craigslist was kind of a thing. I recently got on Craigslist and was looking for a job you know, I had a job I was fine, but I thought I want to see if there's anything else out there. And I came across a position in a small boutique functional medicine office working with the MD obgyn, who had her private practice. And the idea was always that I was going to do nutrition consulting, but I kind of started off doing more office kind of running her office and helping explain things to clients and stuff. And then she ended up taking off into a bigger center and I started growing more skills and was able to take these consults on and learned, you know, by shadowing and stuff, I learned a lot of how to interpret tests and you know, help people with, with how to, to make those changes that they needed to make.That's awesome. Just to let you know, I just got on Craigslist right now and there's no jobs for functional...That was totally a godsend thing. Like, I didn't even look very long. I think I was one of the only people she interviewed like it was meant to be. It was meant to be but it's funny how I found it.You also have some, some experience with functional lab testing as well. How did you how did you make that leap to do that now not all functional dieticians do that.Yeah. So it really you know, it's just as again a blessing of kind of shadowing these doctors and these, you know, people that have been doing this for a long time, they really taught me a lot of what I know about interpretation. I didn't learn it in school, or any of the certifications, you know, that I've done, except for one that's kind of more recent. So I just started shadowing in on appointments, and listening and learning and taking notes and studying and understanding, you know, that these are the actual ranges that we want to look for from a preventative standpoint, and why and how conventional ranges are based on sick population of folks and for the most part, and that there's a lot more that we can look at, versus just some blood tests. I think blood tests are valuable. You know, and urine tests can be valuable, but there's so much more that we can explore and understand through looking at the function of the body, you know, because the body works really hard to keep keep the blood clean, and you so looking at urine and looking at its stool test and looking at saliva to lesser extent really opens up a lot of a lot of areas and helps it be that much more individualized and focused. So that's the other really great thing is that with functional medicine we're always so with functional medicine, we we get to make it personalized and by asking all these questions, and diving deeper into their life and what's going on, helps us determine what direction we want to go.Okay, so I have a patient and I'm treating them for this is whatever I'm treating the for anything, ulcerative colitis. I say you know what your I don't think that your diets on point I think your whatever so I send them to you what would be some typical labs that you're talking about that you would want to look at that, that me using the do ologies of quest lab or lab core, you know, the two largest ones that have the standard ranges, you're saying that you can dive deep Just give me an example of the, the elevated care that you can do from at least a lab perspective.Yeah, so like, if it was a digestive patient, you know, and they hadn't had any stool tests done anytime soon. I always like to look and see what they've got what they had done, right. So we don't rerun something that we don't, you know, is not necessary or helpful. But I would want to look at a stool test and beyond what most stool tests show, which are just some of the pathogenic bacteria or some of the pathogenic parasites or something maybe pretty limited, you know, and with a stool test, we can actually look and see who's all living in there, right, because we know how much the microbes play a role. So it's bacteria fungus viruses, worms, parasites, all those things plus digestive function. So looking at, you know, bile acids, pancreatic elastase looking to see how those organs are functioning, and then and then also inflammation and different markers from the immune system, I think is really helpful to put it all together and then use nutrition and supplements and lifestyle like mindful eating and, and whatnot, you know, to help them to eradicate those things. So like a colonoscopy or endoscopy or biopsies can be helpful, obviously, you know that and for structural findings and different things like that. But with a stool test, we can most often figure out Where's that? What's that is the source of the inflammation, you know, a lot of times so what, how can I help kind of coach people through understanding that they can have all these things going on without even having gut symptoms your person but you in your recommendation, you know, obviously would, but there are several people that I see that that I, I do stool tests with because what we know about the connection with immunity and neurotransmitters and you know, just overall health and in vitality metabolism, so that would be one might be, I might want to look at nutrient and vitamin levels through blood and urine. So, there's a really cool test from Genova called a Nutri eval. I don't know if you guys have heard of that before. But it looks at vitamin and mineral levels. It looks at a snapshot about neurotransmitters so some of the organic acid metabolites. It looks at heavy metals in whole blood. So that's kind of cool, you know, to show people cool i guess is a relative word. I got a lot of mercury.Any chance that you've been eating paint? Bad news? Good news. I figured it I found it. Hey, I've got a question for you Gabrielle when in utilizing these functional medicine tests because I think that we all know that they are on they're on the the early stage of really figuring out and they're learning each month on what new parameter matters most and then and we've all three of us seen where they thought the emphasis would be here and sometimes they dial it back only to find out that it's actually in this direction. Have you seen or ballpark? I guess I know you've seen it, but can you ballpark about how many people do you have an initial study on that after good guidance, good counseling and obviously adherence or compliance to what you lay out for them...how many how many or what what percentage roughly come back and then in six months or 12 months have shown an improvement a desired a desired improvement in those tests?And then before you get to that, also, if you can figure out what happened to Eric there, we had that Pettit mal seizure where he slowed way down and then sped way up. You could fix that also. Is that is that not something that y'all wanted?We're both staring at you in slow way down and then.Yeah, yeah, I dialed all of that in.So I don't know. You know, I wish that we had something a little more concrete, you know, to offer. No one's doing any real research on any of that in our office. But I would say I don't ever have anybody not get better. It's just to what degree did they get better and how fast so yes, I like to kind of set the stage of depending on what's going on. Most people are not going to fully eradicate the situation, you know, sooner than six months. But they're going to start feeling better within a couple weeks if they really start changing their diet,You could say an improvement in those at least correlates you're seeing correlation between improvement in quality of life happiness. And I would assume that certain symptoms would always include the general anxiety, sleeplessness, etc. as those things begin to improve, even though this is somewhat relatively new science, you're seeing a correlation to improving the quality of life, as well as an improvement in these these essays or these deaths.Right, more so what I'm kind of measuring is this Yeah, the conversation that we're having what they're telling me is going well and you know, what their mood is, but I also have a symptoms questionnaire that people fill out that rates different body systems and different symptoms within those body systems. So like, there might be mind or emotion or digestive or skin or whatever. And so then they put a number out next to the side of it, and I'm always looking when they come in for the next visit. Did those symptoms go down? Right, did they get better? That's always the goal. And then if there's an outlier that didn't get better, right, like their sleep still stinks or something, then we're going to talk about that, you know. But so yeah, I think everybody is always getting better. Just some people need more therapies or more intense, you know, surgery or medications or something that absolutely happens, you know, but, but more often than not, the folks that are coming to see me are people that have actually seen a lot of other people with no to no avail. Because no one was really looking so much at their nutrition and lifestyle, because that's really where the money. You know, that's really where the money is, for most people. When they can change those things and get ahold of them. Things get better. Did I answer your question?No, totally. I mean, because I think that it's such a relatively new approach and a new science in Canada. I've had some pretty extensive discussions on even something as, I say simple but people talk about all the time. It's fecal testing, and what out of all of the different things and there's various different labs that come and pitch his clinic on the services that they can provide. When it gets down to it, there are certain elements that people feel very, very dialed into on what those results may mean and a lot of the others, I think you were very honest, it's it's new, it's it's how are we collecting this data to make certain that we're heading in the right direction? Ultimately, a patient who doesn't feel well once they begin to feel well, you're at least solving some of the issues if they're sleeping better than you're solving insomnia, if they have decreased anxiety, then we're at least solving their anxious issues. So it makes sense to me that if we're starting to find correlating trends, then we're there we're at least beginning to crack the code on a lot of this functional medicine testing there, frankly, 15 years ago just did not exist.Let me ask you that question from a from a clinical standpoint, so what I get away I get a lot of second opinions and a lot of people have actually found me through a functional medicine route, where they went allopathic. And then they went through a bunch of functional medicine style. Like all practitioners, there's good bad, there's things and then they end up spending quite a bit of money. And then they'll show up and they'll have five different stool studies from different places, Genova vibrant, wherever, and they'll just hand this big packet to me and go, what's this? And I remember listening to some different practitioners talking about stuff like this, they're like, look, we can analyze the stool, how we manipulate it is kind of or how we get it better is sort of the hard part. Being able to get a genomic sequence is the easy part. The hard part is what you're going to have to do with that. So what would you typically do? And I said, I was turned on to it. You know, we developed Atrantil for bloating and stuff like that. And I remember I was asked to give an IFM talk, the local Dallas IFM group and Betty Murray was there and a bunch of the other functional medicine doctors were there. And somebody had mentioned that they checked stool studies. And then what they wanted to see afterwards they checked it after treating with Atrantil which has the polyphenols, like in your little Facebook post great. And they, they said that it increased the microbial diversity. So from a integrative dietitian, what would you do with those stool studies? Because I'm flat out, I look at my patients, and I go, I don't really know what to do with this. So how would you and it's almost always the same thing, dysbiosis gluten intolerance, candida overgrowth, and then you have a disproportionate growth of these different bacteria. You know, we have 100 trillion bacteria there. So it's always it's always hard for me to look at somebody that's spending $800 on each one of these stool tests, and go I don't know what to do with it...yet. We're learning first step is being able to, to look at it. Second step is figure out how to manipulate it. So how would what would you do with those stool studies and this is less of an interview question, more of an advice.And I think it's really great to that you're just you have mentioned that we don't know everything that we're always learning, but everything is always growing. You know, I think that that's a real sign of intelligence. And something that functional medicine kind of prides on is is evidence based and just continuing to grow that one size doesn't fit all, right. And so yeah, I think that there's some of the similarities that would happen across the board from different stool tests, no matter what it was, and you mentioned several of them. So, depending on what we find, you know, we might, I'm going to use supplements and food and lifestyle. So let's say, you know, again, if it's an overgrowth situation of bacteria, and if they're having gas and bloating and distension type symptoms, then I may offer the low FODMAP, you know, food plan, which you guys are probably familiar with, just you know, looking at particular starches and fibers that helped to starve out those bacteria and try and work with them on that. If they...How long would you let somebody be on a low FODMAP diet?That's a good question. I really don't try and do it very long. I really try to do it at least for a month. But I don't do it much longer than that, depending on their situation. Now, if they're not somebody that's compliant with taking some of my antimicrobial supplementation or gut repair supplements, or they're not doing you know, a lot of other things then I might keep them on it longer because they're probably still having the symptoms. And I think at least we're starving out those bacteria. But where I'm trying to meet people where they are because another thing to always think about when you when you're giving food plans, or diet protocols around stuff is people's ability to make that food, write their resources, their flavor preferences, their schedules, etc, etc, right and so I can show them this FODMAP plan and say this is, you know what, why this will work and here's the foods and you know when to eat those foods, but then I'm going to take that time to really break down how they can make that happen. And that also determines the timeframe of how long and whether we make any exceptions or not, you know?So this gets into your so that you're the integrative dietitian, but then you have to put on your hat. The coaching hat, yeah.Then you have to do that, because you have to change habits here.That's right.You got to educate and then get them to believe in it. AndYep, educate them and tell them the why and then figure out what their why is and then help them do the things you know. And so, like I like to say it's biology to behavior change. So, you know, depending on what we find.Do you own all these cool quotes that you're throwing out there. Like have you trademarked them? I'm about ready to make some t-shirts.I haven't. We can all use them. We can all share them. You make a T shirt now that you can you can have it that'd be cool. So, as long as you let me wear one. So what else would I do supplement wise? It depends, you know, because it depends on what we're dealing with. But it's Yeah, it's it's helping them to, to take ownership around what they found here and how it got created and then try to help them see that it doesn't. changes can happen without all happening at once. They can happen as the people are ready. So it's all on their on their timeline. And I can give advice and I tell them, I'm never going to steer them in the wrong direction. But they're in charge. Right. And I think that's where the coaching, the functional medicine specific kind of coaching comes in. And why I decided to, you know, to do those certifications and then become national board certified because I really believe that functional medicine, just health coaching in general, but specifically functional medicine is going to be really where the life change happens for a lot of these people, because skill sets like your skill set would be more utilized in doing the actual procedures, explaining to them about the results, you know, and but then they need, they need help doing the protocol to address the results. And so so that's why I think coaching is so vital because it's going to really allow for practitioners to partner with coaches to be able to help the client with their success and their their health because a lot of people just don't have the time or, you know, that really, a lot of times it's the time to take with with people to really invest in that as much as you might be interested in it. You know, you're you're busy doing this and you're doing this and then. So partnering with a coach is can be really helpful to help hold that space for the client. Yeah, I think that's amazing. And I I'm under utilizing health coaches right now in my practice, and part of it is just because the, the demand, that's the, you know, it's a high volume, I get very, you know, second third opinions where we're trying to go through some different stuff. And so as a, as a coach, what I, what I at least tell my patients is that I try and take some of the burden off of them, because what you have is somebody that feels guilty about how they're eating fast food, and they're driving home and they're, they're tired, and I try to explain to them that sometimes it's not you. It's the fact that you've cultured these microbiome that are sending signals to your brain to do a follow up on that. So what I want to know as a health coach are one of the terms that I are one of the things I try and do with my patients is create friction on the bad habit. Meaning let's find a way to make it more difficult for these kind of things to happen. That's kind of how we got people to quit smoking. We just tax the snot out of it and people stopped. So creating some friction. Do you ever have you found little techniques to help your clients overcome? Because it's that first hurdle, that sugar crash the way that I mean, I, I truly believe that a lot of those people, they intellectually want it. But it's it. That's how they grew up. That's where they're at. It's I mean, we can talk about different cities. I was just in a small town in East Texas and my son and I were trying to eat healthy and that was not possible. Just period.Right? Yeah.What are some of your tricks as a coach? Some of your secrets that you win?Um, I think my secret is being mindful and intentional and really trying to be there and present with them to hear what it is that they need. Because everybody is truly different. I really don't even like if we use the sugar craving, you know example. There's probably about 10 different reasons I could come up with right now that people have for why they have sugar cravings. So I think it's taking the time, I think one of the tricks I have is taking the time with them, to build that rapport, to help them understand that they can trust me, that I'm authentic, that we can be honest with each other. That, that I'm going to give them informed consent. So I'm going to tell them pros and cons about things. But I want to understand more about like you said, they intellectually might know that they don't want to eat this, you know, cookie, but then they keep finding themselves coming back to the cookie. Well talking through their day and what else surrounded that and kind of helping them to let me in a little bit to the scenario helps me figure out where I can guide them where I can coach them. It might not be you know, while I think it's helpful to share with them that maybe their yeast overgrowth is contributing to their sugar craving, I want to also spend time talking to them about how what we're doing is helping to get rid of that that threat. And what other scenarios can we do in our life that that also could contribute to sugar cravings? How can we kind of be proactive about not putting ourselves in that situation? So it's kind of similar, where we create a friction, we make it hard for them to do that, that habit, sometimes I go that route, but some people need other types of encouragement or there might be, you know, it might be that really, the reason why they go to that cookie is because they had an argument with their spouse that they have almost every night. You know, and so what needs to be addressed over there? Or is it that they didn't eat all day long, you know, and maybe that's why or whatever, you know, there's various different things. So I don't know if that's the kind of a long answer to your question about what are my like specific tricks because everybody I just try to kind of feel them out. And I probably have a couple of one liners as you can tell, you know, that I throw in and mix those in. But I just want them to know that I'm there for them. And that help is really a cool thing where it doesn't happen in a black and white all in or nothing kind of scenario. It's all every step you take helps you get there, right and figuring out why you're doing it and then coming playing back into that motivation can keep them on track along with education.It seems to me like that such a such a key part in so many things on changing one's daily habits into better habits is just simply recognizing what puts you where you are. And you hit the nail on the head. We've we've talked about certain different things, maybe not necessarily in terms of just health coaching, but I completely agree with you Gabrielle, if you can identify what is triggering you to do something that you already don't want to do, then obviously, that's not the way to deal with the thing that you don't want to do. So it's, it's more or less, can you improve a different part of your life...it sounds to me, can you improve a different part of your life or change your routine that's going to allow you to not necessarily feel the need to, to break the trends, is that kind of right?Yeah, I think and I think we all need partners. I think we all need help and coaches and support and guidance. You know, I don't think any of us have anything all figured out 100%. So, the coaching can come in and help you shed light on on things that you may not take the time, or have the ability to break it down and see it that way. You know, see it from a different angle,Eric's pretty close though about having everything figures out.Well, that's pretty obvious. So we can all learn a lot from from Eric. I myself. I don't have it all figured out.That's a ridiculous claim. But thanks for playing along with Ken. That makes me feel really well.I mean, are you kidding? I said in the very beginning, I'm learning how to breathe. I haven't even mastered that and I've been doing that for almost 50 years, so.Okay, so I've got something I've got something that Gabrielle shared in our intake Ken and I'm just curious if you can name any of her so we've heard the way that she scientifically thinks through a few things, etc. Ken and I, whenever we scope together we have different days different playlists, we try to listen to pretty much everything. Can you just out of thin air pick one of her top five bands, she's listed five on here I believe no actually she listed six. She doesn't follow rules very well, but she listed six and none of them didn't debut before the year 2000. So all of these looks like they were in in in the 90s. And all of them are are bands I listen to can you name one of them Ken.Yeah so this this should be pretty easy because everybody I've ever met that serves Craigslist loves Metallica.So close but no not even there not even not there.See? She threw me off with the Craigslist thing.Yeah. I know. Her first band listed and I love this because we were just...last week is rage against the machine. Oh, that's awesome. Cake is definitelyCake is a good one. Yeah, Metallica is a good one too.Eric and I are big I basically well we basically always have music going at all times. And so it's a it's just part of our existence. It helps the patients patients come in. If you're a patient listening to this, you know that there's always some music and then it's funny. Because I've had patients for so long that they'll come in and be like hey, you had like whatever hardcore rap playing last time and now you've got some some funky soul going on and I'm like yeah I evolveYeah right like we shouldYeah but check this out, her span is large really because even though these are somewhat related to actually they hit a lot of stuff it's it's Rage Against the Machine she listed Soundgarden which of course is that great Seattle sound then you have sublime, which is a huge...Are you kidding me? I don't like the Santeria buddyAnd she gets into some quest love and she she put on here the roots, then the fugees and no doubt so I Holy cow if I just actually would. I was trying to be funny about the Craigslist, but I probably would have said thoseWe're all in good company here. Absolutely. And there's a lot out there. So you know it's just I was saying trying to think bands specifically right I feel like there's not.This is perfect this is inside these are to me these are not throwaway band names This is they you didn't you didn't go with in the last 20 years you were with people who typically write their own stuff. Lots of bass, heavy, very talented bands. So no, I'm into it. I think that's awesome. Cool, me too. Well, Ken did you have anything...I got I got I got one of the things I want to throw this at you Gabrielle what are the top three things you tell your coaches or that you tell your clients as a coach, non nutritional that you have them do to their lifestyle?Mm hmm. Well, I talked about quality, quality of air quality of water quality relationships, quality of food. But I tell them to move, tell them to move their bodies find something that they likeI thought you said you need to move out of your house You need to move. I tell them to move because it's toxic. And they gotta get out of there, I tell them to move their bodies go outside, get in the nature. If they can do one in the same with that, then that's really, that's really a sweet spot, to get some sleep, to know their worth.That's awesome. It actually seems like it all augments on everything else that you're trying to teach them.I hope so I hope that's the message just to empower them. That's really what I want to do is I want to empower them to know that their choices are super significant, to live a healthy, happy life that they're proud of and show up in the world the way they they want to. And hopefully I can help them you know, accomplish that.You've said the word empower several different times. And I like the way that you're talking about this because you've talked about relationships a few times empowerment a few times, self worth. So I'm seeing a theme here that how many of your clients coming to you, and they do not feel good about themselves. So therefore, it's hard for them to treat themselves well.Yeah, I would say a good percentage. And it doesn't always come out in the first visit. Sometimes I have to dig dig around and I find that but it's not just females, it's males too. And the younger the, unfortunately, some of the younger generation of kids. Yeah, some teenagers that I see.Yeah, so that's that people like you are so important. And clinicians like you are so important, because what I'm seeing a ton of right now is I get people with irritable bowel, Fibromyalgia, fatigue, and they're on four different antidepressants. They're on anti anxiety and they're 22 years old. It's very hard for me to sit down, look at that and go over the side effects of your drugs alone are going to be the uphill battle of how we get you feeling better. So I think that more people are taking that approach is awesome. Were you going to say something Eric?Yeah, actually, I think that's what I'm gonna build upon what she said what you just said. And when you you listed specific In fact, you listed four different things. But the last thing you said was know your worth. But the first three things were actionable. And knowing your worth is a hard thing to do, because now there's instructions on how to know your worth. And then when you ever you said young people in Ken said that your position is very important. I'm just curious if you're trying to coach someone who is young. One of the newest devices that is effective is the cell phone. And do you ever have to find yourself telling someone hey, possibly, if you're looking at your screentime registry per day, which is I think on iPhones, you can set it so that each week it tells you how many hours you've spent average each day on your phone if possibly driving down the pervasive or social networking thing might help them get over some of the driven anxiety or different things like that. Is that something that you ever have to coach someone on?Totally yeah. And so not only from a comparison standpoint and constant stimulus standpoint, but also from a Wi Fi you know, radiation standpoint too. All of that stuff can be contributing to their to their mood. Yeah. So we talk about it from both angles. Hold that thought, I'll be right back.Hey, while he's stepping away, I was gonna say did you did you happen to see that there is a US representative or senator but here recently, they Just came out with a clip where they are introducing legislation to ban Tik tok, for instance, from being used on any governmental devices, especially for anybody in the Pentagon because it is an addictive app that is essentially recording keystrokes, everything so now they're they're cataloguing your passwords. They're cataloguing what you do all day. And it's it of course, it's it's preying upon your emotions, your anxiety, making you feel as if you have to use it over and over and over again.Yeah, they say data is the new oil. Right? So we're everyone's looking to capture as much data and the more devices we have on us all the time, you know, the easier it is for them to do that.So I'm late to the game with the whole EMF thing because Eric and I've been part of several, I don't know what do you call them entrepreneur groups, and there's a lot of functional doctors part of it. About Wi Fi EMF. I got myself a volt meter.Oh yeah. What are you finding? Well here's why I'm trying to do some earthing and some grounding. So I got a silver embedded sheet that I'm now doing it, I can, I can plug this with my volt meter and I will grab my phone and the volts just go up and you're like, ah! And then I was watching a video where some guy walks closer towards a power line and it just starts going up.Off the chart.Yeah. And I'm like, Oh, so I need objective data. So that's kind of my thing. Like if you say that you go EMF Oh, that's quackery. And then I go get something to prove or disprove it. And you're like, oh, man.Oh, wait, there's something to thatWait a minute. There's something to that now I start thinking about putting my phone in my pocket. I'm like, that's a little too close to the nether.Right. Yeah.It's it's funny because when I talk to my colleagues and stuff, and just it just, we're inundated with so much information and you're right, the phone is certainly one of them right now. But when you're talking about this stuff, it's like, if you vomited all that at once at somebody, then you almost discredit yourself. It's like they're all over because you do get a lot of people that that have this passion and when you have a lot of passion about something I do, I tend to vomit and talk about it all the time. I'll listen to a podcast Eric will hear me talk about we need to breathe everybody cover your right nostril, now your left nostril we're gonna. But your ability to develop the relationship with your clients is what's really going to make the difference and your ability to take the time to explain these things validates the actual field. So thank you for doing that. That's awesome.Yeah, my pleasure. I really feel blessed to do it. And it's nice to, you know, see people's people that people to be able to step into, you know, what they want to be and what they're kind of called to be. Not that I'm, you know, my guru healer or something, but I think we all play a role in that and it feels really nice to to encourage people in that way.Well Gabrielle I know that what if people go to livingwelldallas.com that's livingwelldallas.com they can find you as well as the clinic itself is there. What else can you tell everyone about how they would like to connect with a Integrative Health Coach like yourself?Um so I'm on all the social media platforms as well under Gabrielle Randell and then I have a YouTube channel where I have some some videos on there some helpful tips and I plan on continuing to add to that and and yeah on the website you'll be able to see my information and then my email is Gabrielle@livingwelldallas.com. So what I would really like to encourage this was more of a get to know you. Let's just showcase Gabrielle we've got this incredible person in our city. Hopefully we'll able to reconnect in the studio and be more in person. What I would like to see is anybody listening shoot some questions related to this and then maybe we bring her back and it's like a ask me anything episode. We get her kickin some knowledge and stuff like that.Ama. Ama Gabrielle Grandell with ama on GCP. It sounds really good.Yeah, I'd love to come back.Well, that'd be awesome. That'll be easy, easy to do. We'll have all of your connectivity stuff listed in the show notes. Of course, in today's show be listening on the audio platform just go over to gutcheckproject.com. Look under Show Notes for this episode number 37, with Gabrielle grandell, and you can connect with her as well as shoot us a question and we can set up the AMA. Let's see here. You had one of those Pettit mole seizures again, that's so funny. It sounds It sounds so normal over here. And I guess over there, it doesn't at all, but I can tell whenever y'all are laughing halfway through me talking that something is happening.Well, we kind of look at each other through the whole zoom. You know, like when you kind of get an idea of where you're looking on the screen. And so yeah, that is that is awesome. I love where you're coming from I we're speaking the same language, I have a lot to learn. So and that's kind of so i'm i'm excited every time we do something like this, we'll learn a little bit more.Yeah, well I was excited to be here and talk with you guys. I wanted to mention that not only do I see people in my private practice, I also work with other practitioners that utilize me as their health coach. And so I have people in other parts of the country that that have health coaching as part of their program that people have purchased and then they have set amount of appointments with me. And so we do those over the phone or via video using the doxy website right now. Thank you so much for coming on. This is is going to pretty much conclude episode number 37 This is Gabrielle Grandell. Thank you so much integrative health coach and living well Dallas and I say that correct, right livingwelldallas.com?Uh huh that's right.Livingwelldallas.com and we will more sooner rather than later have Gabrielle on for as Ken's already announced an AMA episode which who knows how long that's gonna goYeah we got to figure some stuff out go to kbmdhealth.com look at the information we have the products we have there, and then eventually we're going to get Gabrielle to give us some sort of coupon code for our for our listeners to get to ama or coaching or just just sweet vibes from her just put, just put it out there some self worth VA makes you feel better about yourself.Oh, hey, last thing Ken you Ken you have to do the disclaimerOh, I keep forgetting to do that.Doctors.Gabrielle as it turns out, we're talking about a lot of medicine and things like that. But if you do have any unusual symptoms perhaps a weird rash, please do not use this show for the treatment of that we are not here to diagnose or treat. We are here to give some information and have some fun. Go see your doctor if that rash does not clear up. Anything else?I agree.That's our disclaimer.That's a very official disclaimer. All right, folks, thank you. gut check project and KBMD health community. Gabrielle thank you once again, that's Episode 37. We'll have everything up with show notes if you'd like to connect with her and we will see y'all next time. Thank you. All right Right on.Thank you guys.

COVID-19 Files: Ep. 7

Play Episode Listen Later Jun 25, 2020 48:18

Hello gut check project fans and KBMD health family We are here for what we think is going to be the last installment of the COVID files Episode 7.0. I'm here with your host, Dr. Kenneth Brown. And I honestly we, we got to a point where maybe we've just kind of COVID'd out. So we're going to book in this with some very important information simply because it's stuff that just came up. So what do you say Dr. Brown?Absolutely. I mean, I think a lot of people with everything that's gone on recently, it is just absolute overload. Part of the overload also is the amount of literature that's coming out regarding this whole COVID situation. We hear one thing we...you know, something else happens we know that all of a sudden, there's articles being retracted now and we're going to talk about that and then there's articles where this and that now it early on, if you look at our original COVID files, I really felt like we were doing a great job of staying of informing our audience and we stayed way ahead of the mainstream media. We were saying things quite honestly a couple months before stuff started getting out. And now we're finding out that okay, everybody's now starting to get or everybody you can get a preprint done, which now you can look up and you can do this and that's what we're going to talk about. I do have a kind of cool preprint whether it's true or not, but now it's almost like you have to put an Asterix next to scientific studies that are being put out there. And that's what we want to talk about today. Because as of this week, the who unfortunately got put under fire a little bit for saying some things and we want to talk about that. We want to then hopefully move on, get back to gut check project, get back to talking about food, nutrition, health, lifestyle, biohacking, all kinds of stuff that's a little bit more in our wheelhouse, but we I think we did a really good job of addressing the COVID attack that came on but I think it's, we just have to wait and see how it plays out now and then re circle back when everything's open.I'm in no, no joke. So let's let's just get straight to it. So and I'll preface only by saying this COVID file 7.0. And then we've had the half sessions where fortunately, Dr. Stewart Akerman has joined Dr. Brown to bring pertinent information for tests and interpretation. We've we've really kind of slowed down on trying to dive in much more on COVID because there's just been so much information just like what you said. And then what occurred earlier this week with some probably more misstated information than misinformation. Misstated is the way to say it, yeah, yeah, for sure. It's the World Health Organization which, by which full admission from my end you sometimes you kind of have to wonder what all of their motivations are. However, I feel that in this particular situation where Maria Van Kerkhove or Kerkhove I could be mispronouncing her name completely. I don't want to butcher it.Yeah, well, I've got yeah, I wanted to talk about that because her and I are actually pretty good friends. Yeah, I mean, like the press refers to her is Dr. Van Kerkhove, but I know as Maria Rosanna de Joseph Van Kerkhove and that's how I address her because we're close like that.That's cool, she sounded like she was from Nebraska. There's no doubtMaria Rosanne de Joseph Van Kerkhove. There's some Latin influence we've got some Italian we've got some I think de Joseph is what is de Joseph if you have a D if it's a MC, something McClanahan then you say Irish a de Joseph a D, with a little E. Large J what is that?De Joseph? I'm not really...Van seems somewhat Dutch. Kerkhove seems Scotch Romanian. Scotch Romanian Yeah, yeah. So, but it's funny because this this poor woman was at a press conference and was asked a question and she said something to the effect of basically oh, asymptomatic people probably can't transmit or it was just off the cuff. And literally, within minutes, reporters were tweeting the statement, which then became virally shared on social media, which then was immediately put on the news networks. And then we've got poor Dr. Fauci coming on going aye you know he probably call it i'm sure they're friends he's like, and I'm sure there is good enough friends as me and her are so Dr. Fauci called Maria Roseanne de Joseph Maria Rosanne de Joseph Van Kerkhove. I think and she just went I know Dr. Fauci, I'm that was at a press conference and I was just talking to a colleague. SoSo let's let's break down what she said she she basically interpreted and she has backtracked, but initially she made it sound as if acement....asymptomatic people or people who are not showing symptoms, even if infected, rarely transmit disease. Now this is this was big news because the reasons why we worked so hard to actively flatten the curve was because there was a threat of you may be spreading disease and having no idea. So in essence, what she initially said or the way it was interpreted was, well, what we thought was this massive threat. It's not that it doesn't exist. It's just not quite to the level that maybe we first were describing. And even I when I heard that I turned to you, I was like, did you hear what they just came out with?Oh, no, I mean, that's part of the problem. We're still socially distancing. But as soon as you heard her say that and you got the tweet, you drove the hour and 10 minutes to the studio and I was like, whoa, I'm like, what are you doing we're socially distancing? You're like, didn't you hear what the who said? It doesn't anymore! I'm symptomatic. We're fine. And, you know, unfortunately, you know, I was masked up wearing my body suit and stuff and I sprayed you with the hose, get out of here, go back, go back to Decatur. because we're still socially distancing. Hmm.Well, I think I just offended Eric, because he apparently dropped off this zoom call. So we've lost him for a moment. But it is true. What he's saying is that the who statement that Dr. van kerkhove mentioned off the cuff was essentially I apologize to our audience that I think I offended you when I said go back to Decatur because you you fell off, I apologize. I'm just saying will you please accept my apology and remain on this podcast with me? Yes, I will.Ok thank you. I was really, really hurt there. You're very, very forgiving man. So I was just, I was just reiterating that the doctor said an off the cuff statement that asymptomatic people. But what's really what the reason why Dr. fauci had to get involved. And the reason why it suddenly became spread through the news networks is because everything seems to become political. So that was why did we close the economy down? Oh, my gosh, let's get out there. And, you know, we were just talking on the last call that we just had with our partner, Mike logs in about how he was given the numbers in Texas. Some of the highest hospitalizations that we've had. I mean, I didn't see the article. Did you? Take a look at it? Actually,I did. And I'm going to butcher the last two digits. But essentially, the high watermark I think, was 1900 hospitalizations within one day. And the numbers that they came up with this morning, I believe, is they closed business yesterday was 2500. And change. Yeah, so significantly higher percentage wise, probably for a state of, you know, several million. Still a low percentage overall, but regardless, it's it's climbing and what's very, very important healthcare is trends, because trends are what guide us in what it is that we have to treat. So numbers, maybe not huge percentages. Certainly noticeable but the growth and the trend is is what you need to keep an eye on and currently, we are technically on an upward trend and I and by the way, I'll add that the last three weeks temperatures have been higher, which is something that was thought to be something that would help tamp some of the transmission and infection. That is, that is a great observation because, you know, a two months ago, that's that was a whole thing. China was putting publications out that showed in regions where it was warmer, the disease spread was less. And so we were all like, oh, all we have to do is make to spring and then summer's here, and it'll flatten the curve. And now we're seeing high numbers. And it's like 90 well, yeah, it's somewhere in the 90s. In Texas, at least where where we live, which is kind of northern Texas, in the Dallas area, or, and then so that I mean, I don't know, it we're all learning all of this, so.Yeah. And to be fair, I guess you could still go back to what we've also agreed with, which is the incubation time could be as long as around 14 days. So maybe the transmission happened back before it really began to warm up and maybe maybe with the sustained temperatures high temperatures over 90 in our area will, will help will help to tamp that down. But it's again something that we won't know for another two, possibly three weeks and and in addition to that, something else that's reasonable to expect we all kind of thought numbers would go up because we began to open the state up for business. So maybe this is more than an acceptable number of hospitalizations given that we've more or less begun to open up some regular commerce allowing people to get haircuts, although I haven't gotten one. And you know, different things like that Quarantine quarantine hair going on right now. Otherwise known as late 80s hair if you compare my I look like a super stressed out version of my senior photo right now. Yeah, just wow, that looks like brown. This guy looks like brown with wrinkles. He must have served a presidency term. You're seeing all those pictures where they show everything all the years later.I feel bad I look and I look like I'm just as disheveled as I was in eighth grade right around on 10 speed.Um, a couple quick things I did want to talk about before we jumped into some of the data about the who and why Dr. fauci was a little upset and everything. We did something really cool recently we did a webinar on the endocannabinoid system. And thanks to everyone that joined with that we had kind of a huge turnout on that one. It was super fun. But the endocannabinoid system we're gonna put a link in the I guess down below somewhere where people can look at that and and take a look at the webinar. No you're you're grimacing, we don't have to put a link there.I think we do. I just want to make certain that it happens and that it's functional soI like to throw you out there and just say Eric's gonna handle this and Eric will hand deliver your products.I can say that by next week we will have a page dedicated to all educational series webinars so that if you it will always be free to register and and view the content. We just simply want to be able to communicate with people who find benefit from using the information. So if you wish to share it with someone, all they have to do is become a part of the the KBMD health community and they can access and watch everything. I think that's awesome. And I just want to say that the new plan with Atrantil is that Eric will be hand delivering all orders both online Amazon and if you need it for retail, it's curbside pickup. If you see a very handsome man with a beard and large 80s hair.Much like we're trying to guess at what COVID numbers will be in two weeks. I'm going to guess that here shortly satisfaction scores for Atrantil are really gonna go down.Alright, so, that being said, super cool that we did this webinar. I'm glad we talked about something called the endocannabinoid system which can actually help boost your ability to handle stress. Watch the webinar if Eric ever figures out how to do it, if he finds time between delivering the hundreds of thousands of bottles of Atrantil so this, this poor doctor, dr. van kerkhove was at a press conference said something and Dr. Fauci. Now let's talk about let's look at the numbers. Evidence shows that 25 to 45% of infected people do not have symptoms. 45 almost half of the people getting COVID don't have symptoms. And then if you look at the epidemiologic studies, the study where disease happens in various regions, we know that you can transmit the disease without symptoms. Here's the really fine line. how thin do you want to make this slice? What is a pre symptomatic person and what is an asymptomatic person? That's the key to this thing because pre symptomatic, you're highly infective, asymptomatic, you have no symptoms. This is the really hard thing. And this is why the who statement was a little bit difficult because if you're pre symptomatic, you're very infective. If you're asymptomatic, you're half of the people and we know that epidemiologically you can still transmit this virus. So what's the difference? And now they've been going on this significant campaign to try and retract some of those statements. So we've got Eric back. Thank you, Eric, for joining us again. For anybody that's watching this on YouTube. Eric has horrible add and he'll just like space out log out and be like, oh, I was doing a podcast better come back. You got a little issue with the internet there brother?Man we've not had any issues. issues with our conference. In fact, you and I just had a meeting just before this, and we didn't have these interruptions. I'm, oh, well, you know what we knew what the topic is going to be. So I feel pretty confident in it. No, it's awesome. I just I have abandonment issues. And every time you leave I. All right. So we were I was just explaining that the Chinese study mentioned that four out of five infected people don't know that they had it. And they don't know where they got it. So it isn't like they're around somebody that was coughing and all this stuff. And you had mentioned just a few seconds ago about how the SARS COV2 the virus that causes COVID 19 has can have a lengthy incubation period, you start talking about pre symptomatic versus asymptomatic. It's a very blurred line because you can have up to two weeks of no symptoms, and then cough a little and all of a sudden you go and get checked and you've got COVID or the average duration is five days, which means for at least the majority of people, five days, they're walking around shaking hands, saying hi doing whatever, which is why the social distancing was such a big deal. And so the whole who thing, you know, kind of threw a little wrench into what was going on because there's been like three major studies that looked at viral load of asymptomatic patients are similar to those who develop symptoms. Say that, again, the viral load in the back of the throat of somebody with no symptoms, that was diagnosed with COVID. So they were PCR positive in the back of the throat, and then they ended up developing or I'm sorry, that group did not have any symptoms, versus the group that actually had symptoms went in and got it. The viral load was very similar to that, and so, to say that the who was referencing that possibly asymptomatic people are non infective. They've come back since then and have really the doctor Dr. Maria Roseanne, de Joseph Van Kerkhove, has recently over the last day come back significantly and said, look, I was referencing this is the key here. This is the key to this. She was referencing three preprints studies. And that's where I want to go with this. She was not doing anything wrong. She was saying, Oh, I saw some studies kind of like you and I do on this podcast. Oh, we read this study. That it implies this. Does this make sense? Does this follow the trend does whatever. So it's very interesting that she's come back and said, yes, they were preprints it was just said in passing in a press conference probably shouldn't have been treated. It's not who policy it's none of that. So I justActually she was even in a press conference to when she said it, I think that she was kind of more or less trying to satisfy a question that was kind of pulled off sides. In fact, Archie john from Harvard Medical, said that he feels that the scientific arm of the who is very, very, very smart, very intelligent in fact he says they put our own government's decision making kind of to shame However, he said, what they are bad at is conveying information. So he, he's basically saying that their PR department doesn't necessarily coach them well on how to make what they are examining in terms of science without, I mean, this was a firestorm, at least for those who are paying attention. Yeah, think about this. She's an epidemiologist. She's a PhD, she's an MD. I mean, this is probably like a wicked smart person. I...and you know, just got pulled off sides a little bit and just went nuts and then became a political thing. So it's a it's, it's one of those deals. So the bottom line is, basically, if you don't have symptoms, you're still infective. And it can be 14 days before and if you're pre symptomatic, and then I want to throw out a new term. Remember how we always talk about probiotics, prebiotics, post biotics. I'm gonna do the same thing with this topic. I'm gonna say that you are asymptomat...no, you're pre symptomatic, posy symptomatic and asymptomatic. So when you go back and look at this, it may be that a lot of these people said they were asymptomatic or posy symptomatic me, allergies are bad today. I would never think that if something were to happen, they'd be like, hey, you have you have antibodies to SARS Cov2. Have you ever been sick? And I'm like, yeah, because I would think of it as my normal allergy symptom. That's the posy symptomatic person.That's cool that you bring up that delineation, because even some of the fodder on some of the articles written where they were trying to differentiate between pre symptomatic and asymptomatic and it's such a I mean, that's a that's a that's a lost cause unless you have a crystal ball and knowing that you eventually will become sick, you would have no idea that you're pre symptomatic. I mean, it's, it's, it's a weird, it's a weird thing to try to predict.It's, it's super weird. And one of the terms that one of the doctors use, which I thought was really interesting, because I kept thinking about that how thin you slice the salami, never heard that term. Never thought about it before. Never thought about making a close call. How thin do you want to slice the salami, and clearly it was part of the vernacular of this person because they say it all the time. You know, that's a close call that's a thin slice salami right there. Where do they get that?No, but so, honestly, we still need to be cautious. You still need to be careful those who are highly susceptible, though, I think that we're reaching that point where we've talked about it multiple times on what type of body habitus, etc, is going to be most at risk that hasn't changed. The elderly, the obese, those with comorbidities, the risk factors for those people, especially if they become infected has not changed. If you're going to be responsible in public, you need to be conscious of doing your part. And trying to do all that you can to not infect someone: social distancing if that's that your thing wearing a mask if that's your thing. And you're also going to get to a point where people are going to become complacent with not doing some of those things because people are willing to accept certain elements of risk. That's just the truth.It totally is. And so let's I want to talk about two things. One, this hydroxychloroquine backlash that's been going on. So this is a great example of what is happening here. So there's been two hydroxychloroquine articles that have now been retracted from very prominent journals, the Lancet and the New England Journal of Medicine. And they've been retracted and they've been used much like the who statement and like a political way, a bipartisan, let's let's just say it what it is. The bipartisan way is that there is a lot of people in the current administration that believe that hydroxychloroquine is very effective. And these two articles were retracted, which is now being used as a political motive to discuss that. Here's the deal is that when you dive deeper into it, both both authors of these articles in The Lancet, and in the New England Journal of Medicine, were using one repository of data and that company has not had a third party audit of this. So don't know how much you can actually trust the data. But the author's if I'm a, if I'm a gastroenterologist doing a study on something, and I say, I need I want to publish a study on the incidence of gastrointestinal symptoms on COVID. Well, there's companies that all they do is just gather data, so that I can go in there and say this. And when that happens, I trust them. Because I'm not the kind of person that would spend another two months vetting them hiring a third party company, nobody is. So you have these two articles that were retracted, and I feel bad for the doctors that's probably spent a ton of time writing this going over it graduate students, I mean, hundreds and hundreds of hours to get a study out and then it's just yoink and it becomes some sort of manipulative pawn in this whole process. So if you read about that, it's basically that this company called surgisphere, a healthcare firm behind all the data would not allow an independent review of its data set. And because of that, the articles were pulled. And they, I looked further into them, and they would not allow it because the people that allowed the data to be given, it's a confidentiality, HIPAA, blah, blah, blah, blah. So it's very, like, I could never let a third party come in and do a third party company outside of my organization that didn't sign all the appropriate stuff to come in and look at any of my patients' stuff. So it's, it's as gray I mean, it's so gray. On the surface, they say ha, those articles were retracted. hydroxychloroquine kills people. And then you start going further and you're like, wait a minute, we still don't know. Wait a minute. the chinese were saying, we're seeing benefit. France, was seeing benefit early on. That's why we went with it. And now, when data's being published, it's retrospective analysis on data that's collected by this company that now is being put into question because nobody has looked at their data. They may be completely fabricating everything, they may be behind some huge giant political thing. Or maybe they really can't share the data with anybody with a third party person. And this is all that we got somebody's doing the work to do this. It's just this is where it becomes COVID overload, dude, I'm just like,Well, you know, I mean, it's interesting, you bring it up, and you kind of describe it that like that, because and just for the record, I think I feel the same way. But let me see if I can summarize what you're just conveying to me. We're out here just a...you as a healthcare provider, you just want to know all that you can so that when presented with an issue, you can most effectively help a patient find a favorable resolution. Unfortunately, it's more than obvious that at certain intersections, politics will force either some information to be covered up, or the wrong elements of information to be pushed out. So that some other agenda or something else can either be satisfied or just temporarily delayed until something else occurs. And I'll only say that it sounds that way to me because I'm not necessarily a fan of any party view, if you will. But I, I just don't think that Trump has it in him to make up a drug name and just randomly assign it to a disease. He's lots of people already don't think he's fit the bill for certain things. I'm just going to tell you I don't think he's ever heard of plaquenil before someone told it to him.Yeah, exactly. So somebody somebody said do this. Now it's being thrown at him. This phenomenal I'm just gonna say phenomenal because I actually looked up her credentials and she is just a badass, like, where she went to school, she went to flew to England to study and all this other stuff, you know, she does an off the cuff off the cuff remark, and now it's being used against her. And, you know, we've got these poor authors and I say, poor in the sense that you know, time money, you know, all this stuff everybody's trying. And as a scientist myself and as a bunch of articles that I'm waiting to publish that I'm trying to, you know, keep moving. I just can't find the time to do it if I carved out this ginormous amount of time to do it. And then it just gets drug over the coals because of something that was completely out of my control. I just feel for I just feel for them. And, you know, I got that being said, I want to talk about one other thing. A cool study that I created. Just came out. It's a preprint It's awesome. But I got it. I'm trying to hold on one second. Let me this is a got a little CBD going on here I'm going to do something It's weird that you have some on you. I know, it is weird, hold on. Everybody's gonna start doing this after I tell you about this article by the way. I just gargled my CBD.He did. Did that pique your interest at all about the article? It's not the way that you normally have told or instructed patients to take CBD.No, we have talked other ways of doing CBD and we're gonna do some serious studies on that once I can gain a little ground on how else CBD can be applied. We're gonna have some fun with that and we'll be talking big time for people but so, um, it's, I mean, it doesn't matter to you, because you got vaccinated for COVID but with me oh, weren't in the White House meeting room when Yes okay for the record I did not so please don't email me that is not something that occurred this is not a hot mic I'm quite I'm well aware that this thing is on.You're the one that showed this to me. Tell tell everybody about a bit. It's a little over a month old but there was I think it was gah I don't remember what news agency it was. It was either CNN or Fox they picked up some guys getting ready getting ready for a press briefing in the White House press room. And one of them was overheard saying something I'm paraphrasing but we can remove these masks, etc, etc. Everyone here has already been vaccinated anyway. And of course, when I played it for you we both just stared at each other and said even if in jest that is really really weird, that's a strange joke.I know, I what I think is funny is that the hot mic got it, and then they put it out there. But there was I well, I mean, I rely on you to show me a lot of this kind of topical stuff that's outIt was very Wizard of Oz the way they explained it, they're like, oh, no, no, that's just how we always joke. And I'm like, I know, you know no one jokes like that...It was a joke. That's funny. We'll just call it a joke. All right. So this. So this preprint that I found, and what preprint means is that right now, more than ever, if you're a scientist, you can get some sort of traction on a journal article, before you have been peer reviewed. Once you're peer reviewed, then you get accepted into a journal. Usually they send it back to you to say, make these changes because we believe that that is hyperbole we believe that that is not you know, in reference one of our editors, one of our experts, and so that's what these that's why we say a peer reviewed journal. So this has not been peer reviewed yet. Hopefully it makes it because it's pretty awesome. The basically what they're looking at is does a full spectrum they they actually are using true a little bit of THC and they use varying ratios of THC but does a full spectrum cannabis plant and they also used below point 3% meaning so I interpreted that the title as does a full spectrum CBD product help with COVID-19 gateway tissues that was the title of the article or and does it modulate the actual title was does a full spectrum CBD modulate ace2 expression in COVID-19 gateway tissues and very, very interesting because there is a group in Canada and what they're able to do is they're able to acquire tissue human grown tissue from a company in Massachusetts that sends that uses this for studies. They took airway tissue, oral tissue and intestinal tissue, hence the gateway tissue. And basically the ways that you can become infected oral back of the mouth, which is why we swab it airway, the lungs and then intestinal, the gut. We've been talking about this and this is how this is where the majority of ace2 receptors are located. So then what they did is that they took those tissues and they caused an inflammatory response in them using TNF alpha and other inflammatory mediators and this induced inflammation. They checked the ACE two levels and they were up regulated meaning during an inflammatory process, or if you are fighting an infection, your ace2 levels pop up, which is exactly what you don't want with COVID 19 because the SARS COV2 virus looks for those, there must be some sort of beneficial effect to upregulate, ace2 and other environments. But during this pandemic, it's considered, you know, a detriment. So then they irritated these tissues, the gateway tissues, how you get infected. And then they exposed the tissues to like 22 different strains of CBD, or cannabis with CBD with varying ratios of CBD to THC. And because in Canada, remember the whole country is legal so they can they can play with THC and do stuff like that. What they found is that there was a consistent trend that the higher the CBD content, the more effective this was at both decreasing inflammation and down regulating Ace two receptors. So my whole tongue in cheek gargling CBD according to this study, in vitro, not in vivo preprint. And if you're gonna go, well, how did they figure out the ace2 levels? Pretty scientific. They did RNA polymerase for the dress. Yeah, they can actually see the ace2 receptors. And they showed this. And so they had me up to this point. This is awesome. So they speculated. Ladies and gentlemen, this is a dismount. Yeah. Well, it was because it's, it was super scientific. And then you realize that there's always a motive, or not always a motive, but there's a motive and, and as a entrepreneur, and as a doctor, I would have left this last statement out because it's basically showing the cards or whoever there whoever, because this was not done at an institution. It was done at a yeah, it's basically a cannabis company renting space at a lab. They said, therefore, further research has to be done. But speculating, looking at the ACE2 down regulation, developing a CBD mouthwash to gargle on a regular basis may be of benefit. Like, I wouldn't have said that. Yeah, you just said your business plan.No joke.So that's why I gargled but there's a really good example of a preprint I mean one week from now, if this if this gains traction and people start talking about gargling CBD mouthwash, remember it's a preprint. And it has not been peer reviewed, and there's probably a lot more that we need to learn about it and blah, blah, blah, blah. But it's at least I mean, you got to encourage the science you got to encourage everyone to get out there and try some stuff and say it.I think it's a great heads up and true and truly back when we were even talking about lung infection as it is related to inflammatory markers, and COVID I guess it was four or five weeks ago, knowing all of that and and the circulating cytokines and TNF alpha, and in the presentation of Ace2 receptors being associated with that. What we're saying is is not really that big of a deviation to that controlling inflammation with a healthy ECS is still paramount.100% which is, which is why the article made total sense to me because during that webinar, we talked about how your endocannabinoid system regulates your immune response. It makes sense that if you now what the what they did get into they just had a tremendous amount of great science in there in this article and they were talking about the full spectrum the terpenes, the polyphenols, the flavonoids that all have a inflammatory cytokine balancing proportion. And so this is another great example. They said, This is why we believe that a CBD isolate will not exact the same response, and I I like seeing companies say stuff like that, because I believe that Mother Nature grows it better, than we can actually produce in a lab soAnd that's not even just a shot across the bow. That's just the truth. I mean, in my opinion, the the natural, the natural compounds that we typically consume, they're probably assembled that way, by nature for a reason.Yeah, exactly. So kind of an interesting thing. We always want to talk about the science on the show. Um, I think that next time we get on here, we're going to be talking something different besides COVID.We shouldn't shut down COVID all the way. But I do think we need to tell the audience that we I feel that we have given the most pertinent information without a new revelation possible without just drowning everyone in the same the same news over and over again.Yeah, exactly. And it's it just becomes COVID fatigue. Yeah. And we've got we still have to help people I'm still doctor we still got to do a lot of things we got a lot of things that we're working on we got a lot of things that we're looking up we've got I mean, I want to talk to you talk about subjects in the future here I want to talk gi motility valle nerve activity, how to sleep in the best way to get your glymphatic drainage the best glymphatic I did not miss pronounce. I'm looking up articles where you can prevent dementia by sleeping in a certain position. And there's we got all kinds of stuff. So what I what I would really like is ideas. And we're to the point now where we start calling experts to help us out like we did with the post biotic lecture like we have with a few other people have been reaching out to us. We've had a handful of very nationally recognized people going I like what you're doing. Can I talk about my thing? Yeah, absolutely. Your thing is cool. That's that's where we want to go. So if you've got an idea of something, let us know we've got a repository of journal articles that is massive, unlike any other time in history that you can keep that many journal articles and it'll be fun to look back five years from now when we've got thousands and thousands and thousands of COVID articles and then you can arrange them by topic and then show the it'll be fascinating to write an article on the evolution of scientific data on COVID everything is a bell curve where it's just like the it's hot now it's not.I agree. I agree. Well, man, we actually did it. We stayed well under an hour for a whole episode, so I'll let you know what else, yeah kind of amazing.I've been writing some poetry Can I go get it and fill up the rest of the hour?Tune in next time on the Gut Check Project when we have poetry and prose with your doctor Brown.Just not now gonna hang up. Hey, thanks for thanks for staying on the longest you did on this podcast without like leaving so.Yeah at the end yeah I wanted I wanted to stop ducking out for certain be certain everyone to like and share like and share the podcast we are ready to get back into the mode of gut check project. We definitely appreciate everyone telling us your stories how you stayed safe and so many of y'all written back saying that you are finding new safe ways to get back out and about and I couldn't be happier for all of you to resume your normal living and lives and continue to stay safe no doubt.Absolutely. And as always, I'm a doctor Eric is a crna but we are not giving medical advice on this show. We are strictly doing this to try and entertain try and educate do not take any this information that we give as true medical advice, or, as it's always fun, always speak with your doctor.Oh, and just to add, we are having today's episode and it is in the midst of the seriousness that has fallen out from George Floyd. We do not take any of that lightly whatsoever. And our thoughts are certainly with all of those who are struggling to handle this unfortunate situation, top to bottom and I'm hoping for some meaningful change that benefits everyone. No doubt.Absolutely. It becomes very hard to every time that George Floyd is brought up, it becomes extremely hard to really think about anything else. And then the events that followed and we are no mine, or no way undermining any of that. There's no way that we're belittling the situation. And honestly, I'm encouraged. We're a few weeks out now. It seems that there is a movement that's going on. And one of the things that you and I both really like is we like music. And when you when you look throughout history that voter reform, women's voting rights workers unions, or workplace things, everything had a protest that sparked the interest of people that then resulted in a change. And I'm really hoping that I have a 15 year old boy and a 13 year old girl that we can look back at this in a very short period of time I was gonna say this large number of I hope it's next year that we can look back and go remember when things like this happened. Now they don't we've made changes things are better.Without question, you and I, I think have very diverse histories while we grew up, and so I think Sometimes, even though I definitely wouldn't characterize either one of us as having race relation issues, even sometimes those of us who don't, we have to be aware of the complacency that that may occur, and then strive for better change. And that's what you really should be doing that with everything in your life. That's what part what this program is about, we don't want to become complacent in healthcare. We don't want to become complacent with social issues either. So,Yeah, absolutely. Which is we've talked, you know, we work together and so we talk and it's it's just one of those things that it's disbelief. It's just disbelief. It really is. And if it and, you know, if I'm sitting around with somebody that went through World War II, like yeah, this is I thought about that. If I'm sitting with somebody went through the civil rights movement, they're like it was we were in disbelief then also. Like every time that a major change is gonna happen, disbelief happens. So I don't...If the topic is a little uncomfortable, but the truth is, if it's making me uncomfortable, it's gonna motivate change. And that's okay.Yeah, yeah, yeah, totally.So well, again, everyone thank you so much for your support, like and share. Please support our sponsors, unrefined bakery Atrantil and of course, you can always check in with us at KBMDhealth.com. We have the new webinar educational series page that'll be popping up. And there's KBMD CBD, that Dr. Brown's holding up.Look at that webinar series. And then of course, order your Atrantil and have it hand delivered by Eric.That is not gonna happen. Thank you, everyone. Y'all have a great day.

COVID-19 Files: Ep. 6.0

Play Episode Listen Later May 28, 2020 48:48

Welcome, everyone. It is now time for COVID Episode 6.0. We have an incredible special guest this time, of course, I'm Eric Rieger with your host, Dr. Kenneth Brown. But today, we have Aubrey Levitt. She is the CEO of Postbiotics Plus. She's very much into research and an incredible entrepreneur certainly knows a lot of the people in the scientific community that have inspired Ken and I to dig deeper to look further. Without further ado, Ken would you like to say hello to Aubrey, and we'll get started.So you can imagine my excitement when I found somebody that was discussing postbiotics also. So Aubrey, thank you so much for coming in. Eric, do we have any...we need to shout out to our sponsors real quick? No, we don't have to do that. We just did that. You're all you're all here.So Aubrey Levitt. Oh my goodness. This is so cool. I felt like I was alone on an island discussing post biotics and then I have this little routine. I'm a very routine type person. I like to work out and go to the sauna. And I do a little mindfulness meditation. And then I just kind of scroll for the last little 10 minutes on podcasts and I just typed in postbiotics and I couldn't believe it. The CEO of postbiotics plus I'm like, not only does she know about it, she's an entrepreneur. She's smart. And she's got like, and then I went to your website, I'm like, she's got like six PhDs working for her like, holy cow, we have got to track this woman down. So I apologize that I stalked you. But thank you so much for coming on the show.No I was so happy about that. It's so nice to have somebody else on this island with me. Yeah, we put our stake in the ground like postbiotics and then echoes for a couple years, just looking back but no, it's very...So we're calling this COVID episode 6.0 because although we're gonna talk about the microbiome I want to let you in on something that you're doing. So congratulations to you and your desire to go through science first, hire these PhDs make something effective because you're going to change the world like I believe that we're helping to change the world. A article just came out this month, discussing the gut, the actual title is this gut microbiota and COVID-19 possible link and implications. And then another one just came out that said a comprehensive review on the effect of plant metabolites on Coronavirus. Plant metabolites means postbiotics and then somebody that we will get you in contact with is a PhD that we're working with her name is Silvia Molino, she did it to get her PhD. Her postdoctoral study is so cool. She actually looked at invitro digestion and fermentation of stable polyphenols. So she was able to do an in and of course, invitro means in a lab. So she was able to show the postbiotic effect once through digestion and then once the microbiome comes in contact with it. Absolutely brilliant and so cool. So COVID you're making a difference!Yeah. All across the board. No, yeah, I just want to say that one of the things that started this fascination for me was you just look at fermented foods, right, which are full of postbiotics and how much of a role they have played in every culture. And we may not have known why in the past, but when we're looking through the lens of the microbiome, we can see maybe a deeper into what's happening here. You know, I know people know probiotics and they know prebiotics of fiber. But when the probiotics eat the prebiotics, then this magic happens. And that's what's also happening in your gut, right if you have all those elements working.Yeah, totally.And I think why and what I've seen also why it directly relates to COVID is, you know, people are getting are at risk for secondary infections. And also people are getting antibiotics and whatnot. And that directly destroys the microbiome as we know, which leaves them vulnerable to being populated by whatever's there. And, and weakens them.If I'm knowing that kind of research and listening to the PhDs while y'all are constructing the studies, and or the clinical trials to find out what is actually going to work. What are some of the endpoint measures that you that some of your PhDs are examining? Is it because they're looking for what the bacteria will do with the things that you present like postbiotics, as you mentioned before, and how do you measure that, is it like short chain fatty acid stuff or what...We were looking specifically at one thing and just diversity overall, so we were looking at a point of injury. So the one because we wanted to kind of pare it down to. Okay, we know, we're researching the microbiome, and we're looking all these various things, but it's a complex ecosystem, right. And the one thing we do know is that when there is a lot of diversity that always correlates with health. And so we really pared it back to that of okay, but in our modern lifestyle, we have many, many things that affect that diversity and really, you know, strip it. So we looked at antibiotics first in our first study to say antibiotics is one of the harshest things that wipe out gut diversity and leave us susceptible in this window afterwards to either an opportunistic, you know, pathogen taking over or maybe just not recovering to the diversity that we had before. And so we did a study our initial study was to look at these antibiotics because think about it, also, people are coming in for maybe a sinusitis. So having their gut wiped out is a, you know, side effect that is not intended. It's a consequence that's not intended. So we gave them a fermented herbal product, which is full of postbiotics, because essentially, we put probiotic bacteria with the herbal components and it's breaking them down with we gave them that with some live probiotics as well. And we had a control group and we we took their stool samples to see if we are protecting their diversity. So right when they got the treatment, and then you know, all throughout the treatment and 10 days after, and we saw Yeah, so the endpoint was gut diversity is looking to see if the ecosystem was intact.I couldn't agree more and Brown we've talked about this in the past. And of course, we've seen this in the hospital. Oftentimes when people are given really powerful antibiotics and they come to the hospital. Unfortunately, the end result is often c diff, and it's exactly what it does. It goes through it wipes out all of the bacteria we and it tears down all c diff is all that's left in incredible diarrhea which persists forever so that you're certainly speaking I think that bringing up c diff is probably the most extreme version of lack of diversity because you wipe out everything but one particular bacteria that then populates so it's almost like having a neighborhood where only one family dominates and they decide what happens well c-diff kills people. It's very serious. I'm a huge as a, as a gastroenterologist, I reluctantly ever try to put anybody on antibiotics and I see So my research was in bacterial overgrowth SIBO, which is, which is a consequence of antibiotics all the time. My classic patient would be somebody that said, I got a sinusitis just like you said, five years ago, took this big round of antibiotics and I've never been right since. And that's that's the patient comes to me as a gastroenterologist.Yeah. And I was that patient because when I was a kid, I had antibiotics probably every week for years and then I had to go in and have two weeks straight of antibiotics, because I punctured a lung. And so they put you on IV antibiotics. And you know, ever since then it was just sort of this imbalance that couldn't get. I couldn't figure out how to right. And I didn't even know because that was sort of so early on. It was just this uphill battle that I wasn't aware of. So that was one of the things behind of like, you know, I could do everything perfect, but the moment too much stress would come on or whatever else would happen, I would fall back on my resiliency wasn't there, the normal resiliency that you would think you would have.So I could talk postbiotics all day, but now you just got me super intrigued about Aubrey Levitt. And how I built this, how does a woman this powerhouse CEO doing this? You just said you essentially had a very traumatic childhood, what was going on?Well, you know, it's a bit of a layered story, but it was I think it started also with this more, you know, trauma when I was a baby of someone had broken in and I actually had a memory of it, which is even weirder, you know, with a gun, but it put me on this hyper vigilant, very stressful response for years after where I was watching the window and the door couldn't sleep. And you know, this leads to an increase in illness where I was having strep throat probably every week. And I'm only putting these pieces together now actually looking backwards retrospectively, but you have these series of illnesses that which lead to pneumonia and then lead to puncturing a lung. And this is all pre second grade, you know, that happened in second grade. So you're on, you know, just a massive amounts of medication, and not compared to maybe some to what some other kids are having, but it was a lot for me at the time.I mean, I would argue that getting antibiotics that often could be one of the most traumatic things that somebody could do because you will never be able to rebuild this microbiome.Yeah, it becomes and then you only realize later how much it's really affecting you. It throws off your hormones, it throws off your immune system throws off, you know, all sorts of things that were just out of whack with without a real explanation. You know, you'd go to see these various doctors and they couldn't pinpoint what was the root cause.Wow, how are your parents through this whole process?You know, I don't think anybody thought anything of it at the time, right? They were actually very healthy and very conscious of all these things and did their best. But, you know, what are you going to do when your kid has 104 fever every other week? Right? I mean, you just don't really have a choice.Yeah. Wow. And that is wild. So I would, I would even couple that did on top of that. On top of the biodiversity that's being eliminated through long term antibiotics, you've also got, I mean, the stress of anxiety, which is obviously something that you're referencing, if you're staring at a door or window as a young kiddo, and it persists for days. I mean, the time to repair is constantly being thwarted by your body's vigilant state of trying to always be in fight or flight, there is no repair time. That's pretty wild.Yeah, and I don't think people realize how much stress wears on their, their immune system and their body and just like you're saying, it doesn't give you that rest and digest time to recover, which is very essential, you know, to bounce back. So. And I think also that got me very interested in like the gut brain response and how that vagus nerve talks between the two because you're just always reacting. Right?Okay, so we're both smiling because this is just right up Ken's ally. This is exactly whatI just think it's hilarious. This is the first time that we've actually talked. And you're literally mimicking everything that we say. We are a kindred spirit here. We've been on the same island...studying the same stuff.Yeah, exactly. And so, you know, even when we when I created this first product, I think one of the issues that I was finding is that okay, I would take these herbal remedies, I would, you know, eat these great foods, but I still wasn't able to digest them properly or really utilize them properly. And because I wasn't seeing the results I wanted and when I fermented these herbs, what what was very interesting is I actually even felt a focus and a mood difference right away, which is how I got into this post biotic work because I thought, wow, they're like, I think there's GABA or something in here that is different than what was in here when you started with the original product.So you felt it almost immediately.Yeah, I did, I did. And I felt the difference. And so then I went and tested and that there was GABA in it. And also too, if I was actually feeling that and because it was a small amount, I mean and I can't be sure that's just a assumption on my part, but that got me really interested. I started talking to these guys out of corp, you know, Ted Dinin, and they were studying this essentially how the gut communicates to the brain through the signaling molecules and these neurotransmitters that are released through this fermentation process, even if it's in your gut. And so I just went down this rabbit hole and ended up partnering with the scientists out of Memorial Sloan Kettering. Now he's at NYU, who, who was also interested in the same thing of these metabolites. And not only they also signal to the other bacteria in your gut, so there's just this constant communication going on between everything. Not not to get too in the weeds,No, totally because this perfect, this is the conversation I have with my patients all the time, is when pharmaceutical companies and I'm not putting them on blast, but when pharmaceutical companies try and do something they tend to focus on on a molecule that they can patent. And what we're learning is that the microbiome is way too complex, where we're at right now with our, with our research, so you can do these giant stool studies. And so I get all these people that come from functional medicine doctors with these, these gi DNA analysis, and they're like, Yeah, do something like that we can do the test, you don't really know how to manipulate 100 trillion bacteria. Exactly. And so what I tell everybody is, we do know that if you can diversify, they will figure it out. Meaning they when you have a proper diversification, a proper signaling mechanism where they will keep control of each other, and they send signals to your brain, we now know Eric and I did a whole episode just on the negative effects of short chain fatty acids, when they're out of proportion, meaning butyrate being real good. But yeah, if you have too much acetate, if you have too much propionic acid out of proportion, that crosses the blood brain barrier and creates that that gut brain situation. So it's all about just let your body let those microbiome, figure it out. We're not going to out think them.Yeah. And that's, that's also something that really excites me about this whole field is the ecosystem approach, I think is really an opportunity to look at medicine differently than how we've been looking in the at in the past, like this lock and key approach is doesn't work as you're saying. It's sort of the it's very complex, it requires more systems medicine approach of looking at how, if you touch this point, it affects this whole area around it. And I think it's also to me, the one area that's speaking to all different fields, you know, it's speaking to Western medicine, allopathic medicine, speaking to functional medicine, and it's kind of everybody because we don't know exactly what's happening here. But we all agree, it's important, and we all agree it matters. And that that hasn't really happened before. I mean, you guys are the you're the doctor, so maybe you could speak to that more but that's, that's what I see happening. And it's also saying we can't outsmart it. We have to work with it.Yeah. And that's where the whole, that's where I got really interested in the whole postbiotic thing because that's when I started doing. We started realizing that when, when you start decreasing the inflammatory response in the body by eating a different type of diet, I start asking why. And then that's when I started meeting scientists that said, Oh, it's because you're producing, urolithin or you're producing, you know, now a GABA. I didn't realize the GABA. So that's what's so fascinating. So I'm a doctor. And I imagine you've got what six or seven PhDs that you're in this postbiotic thing. What is how did you end up you were sick and then then you sort of jump forward and said, then I started this company. How did we get from there to here?Yeah, God, it's been a windy road. So I you know, I was a, how do I say this? So i i got obsessed with the science part because I always do have to measure and kind of look at...okay, starting with an idea of something that I may feel in myself or that matters to me, but I wanted to look at, okay, how can we measure this in a larger population? Like, it's not enough for me to I didn't want to go out there and just create a product and see what happens? And I guess Okay, so one step back, I do have a background in pharmaceutical advertising and marketing or whatnot. And so it started there. And I was working those jobs and I thought, okay, I, this is not what I'm going to look back 40 years from now and be happy with what I created. I wanted to go out there and solve a problem. And then once you create that solution, then I have to go back and measure and make sure it works. So that's what led me down the science path. And it just it wasn't necessarily the intention of starting a company. It was always coming from solving a problem and wanting to find the answer that didn't already exist. And if you're looking for an answer that doesn't already exist, then you have to test that answer multiple times before you go out there and offer it to somebody else. So, that's sort of the windy road there, I guess.Well, I'll tell you what that is, is that's you've when we you've said several times, allopathic and naturopathic boy, if there's ever anybody who I would not believe would somebody with a marketing background in pharmaceuticals that came up with a novel idea, usually its market first we'll worry about the science later. We're going to make cash on this thing. I've gotten a lot of flack for that. No, not flack at all. I'm giving you so much props you lead with science first. I mean, that is amazing. Especially because you come from a marketing background, holy cow.But to me the best marketing is truth and honesty. Right? And that speaks for itself. And so I was not interested in this...okay, you have this end product and you put a shiny package on it, and you hand it over somebody it's like how many of the layers can peel away so that you really have a clear understanding of where something starts and what the thought process is behind it and you and you just communicate that clearly at the end of it. And that's that's where I think things are going even on a marketing standpoint, but he you're just telling a clear story of why you did it and then what it is and why it works.I could not agree more I think the most stable marketing is knowing that your story is true, can be proven, can be reproducible. Generally, those who just flash in the pan the the charlatans are always revealed over time and then it's just it's just a trend or a fad that fades away but what you're doing is very much in line with what what drew me to work with Ken it's this is what I believe we'll figure out how to tell people about it later, but this is what's working and that made a lot of sense to me.And and even if it does, if it works the other way, do you is that something you really want to be a part of or like is that like I would lose interest over time. So doing it for me more than anything. And then I had to turn around and be like, okay, now how do I find a business story around that that other people get behind? Because I want to do the science for me, because that's what I need to move forward. So it really came from that place, read more than anything else. And to say, Okay, how do I get scientists that are smarter than me that are gonna think they're gonna challenge me? And then we're going to do the research around it and find some answers.There's so much similarity here. You being a CEO now, I had no business background, and now I'm in the throes of essentially, you know, I mean, it's a five year startup and I realized that Apple was a 20 year startup and Right, exactly 20 year startup and all this other stuff. So you you get that that side of it. I was super impressed with your team. I mean, you are just filled with PhDs and a couple MDs.Yeah, yeah, we got really lucky of and at this point, everybody's kind of donating their time. Like they've got on board out of passion. And that's what I think is even more exciting is that they believed in the process and we just kind of found scientists that were really obsessed with what they call this ecosystem science and looking at how these interactions happen in the microbiome. And I love the idea of ecosystem science that encompasses so much and it actually flies in the face of what Ken and I both kind of find challenging with, unfortunately, the pharmaceutical world which is just trying to find that one little bitty active molecule to try to solve all of the issues with that because it doesn't generally work that way. That being said, what are the goals with the company and utilizing ecosystem science? Where do y'all want to go? What what is what are some some pinnacle finish lines for y'all?Yeah, I mean, what's so there's two things that we have really exciting on the horizon and one we we are working now. We just talked to a doctor at Memorial Sloan Kettering and what the research they've done at Memorial Sloan Kettering is a cancer hospital. And they really looked at how diversity affects cancer patients. And that's been something that was, you know, a long term almost impossible thing for me and and the fact that we're actually pursuing being able to do that is exciting. And what they found is that so they did some FMT studies there. And they really found that if a patient comes in and they have higher diversity, then you know, when they go through their chemotherapy, and then their antibiotics and the most severe treatments, for the third, specifically working with bone marrow transplant patients, the patients who have the higher gut diversity do better. They surv...they're more likely to survive, it actually affects survival rate, and it reduces complications. And so this has sent them down the path of really looking into what can they do to protect the gut diversity and help these patients and so one of the questions they asked which I found fascinating is okay when you receive high doses of chemotherapy and antibiotics is there really anything you can do, or is your gut so destroyed at that point that it doesn't matter? And what they found was actually even a little bit helps these patients and helps their survival rate. And what that means is even if there's no intervention, so they may just happen to be someone who bounces back better than somebody else. And so, and they bounce back to a just slightly higher level than the other patients whose guts destroyed that slight increase in diversity, they do better. So that means even if they eat a better diet, they're potentially going to do better, which is to me huge because you can come in with something that is a more dietary or intervention and improve their outcomes. And so again...Very, very interesting and very congruent, Brown, with what, what you've been talking about even back to the inception of Atrantil. We, we have what we think are these incredible polyphenols this polyphenolic blend to feed bacteria. But, you know, the opposite needs to be true. Also, if if the correct bacteria aren't there to be fed in the right ratios, then we're just not going to have the byproducts, the postbiotics that we need for the body.Yeah. So Aubrey, so I'm sitting here listening to you, and I'm thinking, okay, so we talk about bio diversity and all this stuff. But the reality is, is that the bio diversity leads to this complex cascade of things that happen. Yes. And if I've got in my world, gastroenterology, I've got patients that have their colons taken out due to ulcerative colitis, due to cancer, due to different things. And we've actually talked, we've got one of my graduate students, actually, Angie will be very excited to know that you came on. I've got a graduate student that Eric and I work with carefully, and we started discussing this that well, what happens nobody's talking about If you don't have your microbiome, how can you make sure they have sufficient amounts of butyric acid? How can you make sure that there's urolithic come out there? How can you make sure that now Gaba and now we know that are they getting the appropriate amount of vitamin K, are they getting the glutathione things that we know that the bacteria break down, nobody's talking about that. And the ability to say, okay, during this acute process of getting chemotherapy, I would almost think that your particular product should be the protocol to ensure that there is something.Well, and that's what I think we got passionate about if there's nothing done to support the body to recover better when certain treatments or therapies are given and why not. So it's, you know, I mean, I think it brings me back a little bit to this COVID situation, what what's your best defense, your immune system, your own body, you know, and I think that no matter what you have, no matter what treatment you're given, your own body's going to be doing some of the legwork to get you back to where you want to be, or at least even to be able to handle the treatment better because a lot of these treatments are so harsh that they're also taking a toll on your own immune system or your own body in various ways. So, and we're not doing anything to help mitigate that or support the body as it's recovering. And that seems like an easy place to intervene and have because it's, it's gonna fall back on that on your body anyway.You know, I'm sitting there thinking about you as a young girl looking out the window, being hyper vigilant with the sympathetic nervous system, and then I'm thinking about a cancer patient that wakes up and goes, oh, shit, I have cancer. That thought sympathetic nervous system goes up. Exactly. Then a nurse comes in says, Remember you have chemo. Oh my God, I'm gonna have diarrhea, and nausea and vomiting. And I mean, you cannot think of a worse scenario, then and my, I mean, we've treated a ton of cancer, and the thought of the sympathetic nervous system going overboard the worries that are going on the financial stress, all this other stuff, it's very similar to the COVID situation. So similar,And that's our lifestyle these days, is this a high, heightened, stressful situation is we're constantly under stress. And so, and I think why, until you get something more severe, a lot of times, we're not thinking of what the effects of this are. But really the goal would be anytime you're sort of hitting a heightened stress, how do you balance that with also protecting yourself? And we're not really ingrained to think that way yet. You know, because it's having one round of antibiotics, we should be doing something to build ourselves back up to protect our gut microbiome. So that's why we looked into that in the study of like, how do you protect the diversity and make yourself and help yourself bounce back, right? Because that directly affects your immune system, which is suppressed during that medication and it's going to need to bounce back, you know, the microbiome helps with that. So that should be when you're in a stressful period when you get you know, because then we may not have it cascade into these larger problems, we start looking at it early. But then again, when you have the most extreme problem even then it helps you bounce back. And I, I just keep seeing this also vision in my head of the COVID situation of what happens when the whole world takes a break for a little bit. You saw how even like nature bounced back so quickly, right? Like the amount that we can all bounce back is actually incredible. If you just give a little bit of help...for a second.And I love how you're saying that because there's I have so many patients that when they they do something that let's say that they are...well, we've seen this. So Eric and I, we've we launched a program, Aubrey that we call the frontline program, because we believe so strongly that gut health, you cannot have a healthy immune system without a healthy gut. Because health begins there. And so we have launched a program where we're just giving away Atrantil because I know that it increases diversity. I know that it actually has anti pathogenic activity. I know this and we discussed it as a company, that we have a moral obligation to at least help the people that I'm with like I could, the thought that I could go to my hospital and find a nurse that maybe, you know, if somebody died, that maybe we could have just given them something to help, then that, that really that that drive starts getting me thinking about all the stuff that you're talking about, which is like, why can't we start doing protocols at a hospital that are essentially harmless, which is what you're talking about. There, the risk to benefit ratio, and it's insane the hurdles you have to go through. Like you had to find somebody at Memorial Sloan Kettering, you had to sit down, you had to go through meeting after meeting after meeting he had to then get passionate enough to go to the IRB to go to that. I mean, I've been there. And you're like, for God's sakes! Right. I mean, we're on the cardiac floor. The cardiac diet is pancakes and syrup and...Right, right. Yeah. I in and it's, it's kind of like Why not? You know, it's as you're saying it's why not do something that is going to do now it may help it may not in some situations, but why not?Yeah, we're going so far as we're giving away. I mean, we're losing a ton of money doing this just trying to make sure that if it does, if it can help, and we learned that it helps later, then I would look back at myself at this time and go you're a jerk for not at least trying to tell people. That's really great. That's really great.But it brings a question to my mind, Aubrey with your PhDs and we kind of set the stage here a little bit. So medicine in its early day was all it's all predicated. All the information we have is predicated on people doing experiments it's how we, we came to find everything and then ultimately which seemed like that we're at this intersection where innovation which might occur outside of, you know, the small little nucleus of companies or a handful of doctors is just summarily rejected until finally, over time, it's finally accepted because it happens to work for for someone else, or it's disproven and it doesn't work at all. But what inspires your PhDs to work with a company that's essentially helping challenge the status quo by using natural solutions? Because I know what works for Ken and I, it's because we see people smile and get real relief after trying for so long. So that's an easy one. But what is it about the PhD at that level who's like, you know what, I'm going to go to work today and keep challenging this because why?You know, that's great question. So I think a couple things I do think the microbiome has really opened the door to it's almost looking at it through the lens of the microbiome being complex, and not necessarily as much what the input is, because when you're looking at postbiotics, it kind of takes it one step away from like whether it starts as a natural product or not. I also think this next generation of scientists is they're very, the ones I'm meeting now are very interested in how can I make a difference? How can I not just stay in the lab? And how can I put something into the world and see that research be realized? And I think I happen to meet scientists that were passionate about, okay, this approach of taking the one missing bacteria, or this group of missing bacteria is not going to work. And they were willing to kind of stand on the edge and say that and my co founder who I work directly with, he did some research in Japan and you know, overseas, so I think it really opened up his eyes to hey, there are these things that have been studied for a long period of time that have been used with patients, but it just wasn't under a scientific rigor. So what happens if we look at that information and we start putting it under the lens that we look at other scientific remedies, what will we find? And it's more of just an openness to asking that question, and not really saying, okay, let's pick something more natural. It's more just like, okay, let's open our door to this wider range of things, whether it's natural or not. Let's look at what works.You know, I love how you say that. Let's open the door. Because what I've run into, which I'm sure you have run into, is what I I call cognitive dissonance. If somebody believes something, and they don't want to think about anything else, you described it as opening the door, just look outside and see and keep an open mind about that. That's really cool that you found people like that because when you get up a team, one thing that has been really neat about this whole COVID-19 issue is the collaboration of the scientists around the world. People are running with...people are just sharing data. And they're just saying, hey here, just what can you do with this? And this is, I think that the collaboration that's going on right now with you and your team is so cool, because this whole idea of opening the door and saying natural solutions and what is natural the most, you almost it has this implication that, oh, I'm going to try something unusual. And what you're saying is no, we're going to use our body and we're just going to feed it what it wants and allow the bacteria to do what they do, which is the most basic fundamental thing you can do for your health. I love that.And it's also not looking at the two extremes, right? I think, you know, just because something's natural doesn't mean it's healthy either. I think that's that's pretty clear as well, I you know, that there's, we can't jump to an extreme on either side of this. It's like okay, we can have a wider array of what we're looking at to support the body and then we test it and that's it. So what got the scientists I'm working with fully on board was our first study, we had a control group and we had results that were surprising to all of us because we went in saying, we don't know, maybe this could work. And then we got the results from the first study. So that's really what sealed the deal. Not not any kind of hope around it. Right?Yeah. Let me pin you down a little more. I know that Eric poked you a little bit here. But I'm going to take you one step further. So well, I want to know the because I'm, I'm much like you I'm into the science, but also own a company. And so I'm curious where Aubrey sees the business side of this. Where do you see that going? And you already said that science. You're correct. You're helping people. So morally, you're on the right place, but you also have to pay these six PhDs you also have and, and the beauty of having a successful company is that you can hire more people, more people can can can get insurance more people can, you know, there's nothing wrong with taking a beautiful scientific idea and turning it into a successful company.Yeah, yeah. And I and I tend to think of I prefer building a company where maybe there's a bigger hurdle upfront. And then hopefully, once you get over that, you're gonna have an easier time rather than sort of getting out the gate and meaning if you do the science, you get the credibility and you'll get people behind me and that could be your marketing that you go out the gate with. So what we're hoping is to get this next study done, which we hope we can get this study done with these cancer patients, which is more extreme scenario, right, and then we could put it as a medical food and that would be the hope and then you can also use it as an adjunct when these other medications are given because it's essentially 24% of medications affect your gut microbiome negatively, right. So really want to pay attention to when you're taking these medications, how do you protect it and I think also in these stressful situations, so the idea would be to get it as a medical food and then also take it when you take antibiotics and other things. And so it's not kind of it's when you need it right now like an ongoing every day sort of thing.Well, I see it as a not to have death by 1000 cuts, because I'm seeing going to my company, digestive health associates of Texas, I think that you have a relationship to Dr. Rogoff, one of my partners.Yep. Don't you?Yes, I do. He's a great guy. Yes.So we've got a Research Division that does pharmaceutical research. My background was in pharmaceutical research. That's how I went from that's how I discovered a a hole that they were missing and that a natural solution could fail. And that's very similar to what you did pharmaceutical marketing. Well, it would be really interesting that you got me thinking that I'm like, wow, we could easily do an inflammatory bowel disease study. And people that have had colectomies and see how they feel just a quality of life scale something super easy. Now you really got me thinking like, are they? Are they living their life with one hand tied behind their back? Because we took out their colons?Yeah, yeah. Yeah, no, that would be that would be very interesting to do. I would love to do that. And I think, you know, here's the other side of it if we find something really interesting in one of these studies too to be able to take a collection of metabolites to say to really look at what are what are the predominant ones that are sort of the this lever for the inflammatory or the immune response is is a way to go, you know, because I think we can dig even deeper into so my interest is not looking at okay, these bacteria are the ones that are responsible but which metabolites are responsible in which collection metabolites that can potentially trigger the system?Yeah, fascinating that you say that because I've met with scientists that are actually working for pharmaceutical companies trying to get the one metabolite. And they're trying to get the patent on that. And I just laugh because I'm like, so you get this so does it survive in the gastrointestinal tract? Does it is it the actual one that the bacteria can you have, like we talked about on our show, Eric, you can have too much of a good thing. Your everything has to be in balance. Eric frequently will hyperventilate when I work with him because he thinks that air is good for him, and he'll just do too much. He doesn't do that.One time I realized that shoes made my feet more comfortable. So I just I just covered myself in shoes. Really, really bizarre. Well, hey, I think that, undoubtedly and away from even just this, this, this COVID interview that it's obvious that we could find some synergy between efforts, but for everybody who's listening, anybody else who's interested in postbiotics plus, how can someone else become involved, get in touch with and possibly even help you find what your goals are as well?Yeah, I think the easiest way is the websites postbioticsplus.com and send an email through there and anybody that's interested in helping us move this research forward, that's that's sort of our biggest goal right now or yeah, that's that's the easiest way to do it. I think we're trying to do it in an organized way with a formal study and then we'll go from there, soWe will try our best to do that I have an ask of you though.What...oh noThere's gives and asks, I don't remember his name, but you've got some badass person at Baylor that's head of virology and micrology, microbiology on I saw that on your team on his page. I would love to get in touch...Oh Joseph. Yeah, okay. Okay. Yeah.You've got, I mean, from an academic standpoint, you've got a pretty heavy hitter page. That was a...We've got a good group.Yeah, I mean, like, I'm a I'm a nerd through and through. And so I was like, oh my gosh, look at this. Oh, yeah. And I start looking at the research. I'm like, oh my gosh.Yes, yes, we can. We can make that happen. We can make it, have you talk to him, so...Cool. Cool. That is awesome. Aubrey. For those of y'all who may not know she's the hardest working woman in postbiotics because we're talking on Memorial Day morning. So. Oh, yeah. Thank you so much for doing this. Yeah. Thank you so much for carving out time to visit with us. This was an incredible discovery of synergy between efforts and it's I mean, to me, it's just it's not only a relief, it's exciting to find somebody else who also realizes that there isn't just one solution and to find solutions, it takes a team effort and it's different thanNow we have a club. This is awesome. So so let's start a Facebook group and other things that clubs do I'm not much into social media, but okay, we'll try it. It'll just be awkward staring at each other. Secret handshake.How did this work again? Yeah. Awesome. Thank you guys for having me.I love the work you're doing. Thank you so much for everything Aubrey Levitt postbiotics plus. We're gonna try we're gonna stay in touch. We're going to collaborate like crazy. I've got some scientists you need to meet around the world, some crazy smart people doing very similar things. I'd like to meet some of your scientists, so on and so on. And I don't think that I think that maybe a collaboration between us could probably help out this crisis that we're going through right now eventually. Not in a not in an arrogant way. But yeah, I believe that you see it also that immunity starts in the gut. Yeah, can it can I say one last thing? I know we're, but there's a study. I mean, when you think of collaborating, there's a study. I think it's at Columbia right now that's looking at fiber and inulin, of how it can prevent secondary infections in this COVID thing, and I think there needs to be one in postbiotics of how we can look at.Well, the article that, that that that Sylvia did was really wild because she showed the increase in butyric acid, and it was tenfold. It was 100,000 fold, it was nuts, that I had no idea when you start looking at this where you can actually show this and then we start to I've got this, do you have a Mandalay account, the repository of literature? No.I'll hook you up with this. In fact, we probably team up I've got a I've got an enterprise level Mendeley account where you can just put literature, download literature and put it into files so that you you can search your what you want. So I could like go right now and type in postbiotic you know Sloan Kettering and your your stuff would pop up. It's really it's just it's just a way to collaborate with other scientists that I've really enjoyed so that we can do stuff like this.Great, great. Sounds good.Ladies and gentlemen, that's, that's COVID Episode 6.0 Aubrey Levitt postbioticsplus.com thank you so much for joining us and thanks to our sponsors atrantil.com of course ilovemytummy.com KBMD health and unrefinedbakery.com Aubrey, thank you so much. Ken-any last words?No, thank you so much for taking the time and and on Memorial Day you know not being out on a boat using proper social isolation taking the time to do a podcast. Thank you guys.Have a good one. Bye. Bye.Talk to you soon, bye.Oh, she she jumped out.

COVID-19 Files: Ep. 5.5

Play Episode Listen Later May 15, 2020 34:46

What's up everyone? Here we are, again, we're on episode 5.5, I had to bring back my favorite second favorite co host, Dr. Akerman, because what we're going to talk about today is really interesting. It's the thing that everybody has been discussing in the news. It's how do we test people? Everyone needs to be tested. And then people go, Oh, well, there's these bad tests out there. Oh, with a sensitivity specificity. Nobody's explaining any of it. So as it turns out, Dr. Akerman is really smart at this stuff. And we've been working with a company because we want to introduce rapid testing here in North Texas. And Dr. Akerman has actually helped this company a ton in the type of tests that they're doing, how to explain it. And we're talking sensitivity, specificity, negative predictive value, positive predictive value stuff that I struggle with a ton, well as it turns out, the other guy on the side of the screen here is super smart at it. So Dr. Akerman, can you comment on that real quick?Yeah. First of all, Make sure you don't burn any bridges with your first favorite co hosts.Yeah, right.And, and you're right. I mean, we've pretty much turn on the TV go on the internet, and we're talking about, you know, testing, what kind of testing, is it available, how much do we need? And then you kind of hear from the other side that there may be tons of tests, but too many, and they're not as good. And, you know, you sort of take that all at face value. But what does that mean that the test is no good, what makes it a good or a bad test? And I think that's where, you know, maybe we can do a better job of explaining it to people. And you're right, it's it's super confusing. So...We did Episode 4.5, where we talked about different the mcas and the antibody testing and things. So we kind of hinted at it. But now we're getting to this point where we're saying, Yeah, but what does all that mean? Nobody's talking about it. You You and I got in a discussion John Oliver. You watched a show on that. Yeah. So you know, I don't want to sort of rehash I don't think we're going to do it justice. John Oliver with his extensive medical degree, did an excellent job last week explaining some of the differences between the tests and some of the pitfalls. But I think where we can add a little value to the discussion is to discuss why. Why is it that the test you might go get at your local, you know, minuteclinic, or doctor's office or anything, why that might not offer you the value that you're really looking for.Yeah, and we can we talked before about the pros and cons of that. We don't know that. But what we're going to talk about today is why that's why getting a test may mean something different if you're in New York or if you're in Plano, Texas,right? And you want to know the characteristics of the test the characteristics of the disease process, where you are, and what you're trying to get out of the test. And that will determine whether or not it number one makes sense for you to get tested, and how you can get a better result.Yeah, so we've been seeing that the FDA is saying that you have to apply for this and then you have to achieve a certain. Let's start with the basics, a certain sensitivity and specificity, sensitivity, my friend.So actually, what I want to do is I'm gonna I'm gonna share my screen with a couple slides here. And, you know, I want to I want to go over some important definitions. There's tons of stuff and you don't need a degree in statistics to figure this out. But it can be confusing. So I think if we sort of write it down, and might it might hit home a little bit better. SoI'm still impressed that you actually left New York I really because you seem like somebody who would be teaching at NYU or Mount Sinai or something like that. So, thank you for joining our group.I wanted to have more time for podcasts.There we go.So a couple six definitions that I want to I want to go over here. And the first you alluded to sensitivity and specificity. The best way I would explain sensitivity is what percentage of patients that actually have the disease will test positive. Right? So the true positives coming out of the, of the test. And the specificity is the opposite. It's the percentage of the patients that don't have the disease and will test negative. So the patients who appropriately test negative for this disease process. Those are intrinsic qualities of the test itself. So you can apply the specificity and the sensitivity to any different population because the test characteristics don't change. What does change and this is the difference is the positive and the negative predictive values. So the positive predictive value, are the percentage of those positive tests that are accurately positive, and the negative predictive value is the percentage of negative tests that are accurately negative to say it another way, when I get a test, if it tells me I'm positive, what are the chances that it's right? That's what I really care about. I want to know If I think I have strep, and I go get a strep test, and it's positive, should I be taking antibiotics? And will I get better? That's what we're really asking. And it is different than the sensitivity and specificity, which I will clarify in a second. The other two really important definitions are the incidence of disease and the prevalence of the disease because these are two different things. The easiest way to differentiate is the incidence are the proportion of people who actively currently have the disease. The prevalence is how many people were affected, not necessarily currently infected. So when you talk about it in terms of the test that we're talking about the PCR test looking for active viral replication, that's looking at the incidence of disease, who's got it now. But the antibody testing, looks at who's got it or who had it. And that's more a test for the prevalence of the disease.Well explained. Okay, yeah.All right. So the classic way we look at this is using this, it's called a two by two table or a two by two plot. And you basically up on the, in the in the top bar here, that's the disease or the process that you're looking at whether you have positive or negatives. And then along the margin here, you're talking about the test characteristics, a positive or a negative test. So when you want to calculate the sensitivity, you're looking at this row right here. So the people who have true positives over the total number of positives, so 80, excuse me, if you've got 100% of people ten, let's say people who have a positive test and only eight of them actually have the disease. That means eight out of ten or 80% sensitivity for that test. When you look on the, the the right column here, that's where you're gonna figure out your specificity. That's your negative side. It's the total number of true negatives, people who actually don't have the disease and tested negative over all the negative tests that's going to tell you your specificity.So I remember...Sorry?Go ahead. No, I was just gonna dumb it down to a level that this...I just remember that when I had somebody explained it to me that think of sensitivity and the specificity. If you were to look at these graphs, think of it like a car alarm, that if you make everything so sensitive, so that you could catch the person trying to steal your car. That means that a horn or a loud noise will set it off. If you make it super specific, that it only means that one method of a car being stolen. And so you have this issue of you have this trade off where you have the you want a car alarm that's super sensitive and will catch everything but you're going to get false positives all the time or do you want a specific test that only catches but every once in a while, they're gonna be able to steal your car a different way.Right. And the ideal test is going to be high at both. It's gonna be really great at ruling people in and great at ruling people out. And the question that often comes up is how do you know the sensitivity and specificity? And the answer is you have to validate every study against the gold standard test ones where you know the numbers and see how it performs. The positive and negative predictive values are different. That's looking across the rows. So if you have the percentage of positive tests accurately positive, now you're looking at of all the tests you did and all the positives you got, how many were right, how many actually are getting positive for a person who has a disease as opposed to missing it, right. So to say it a different way, the percentage of positive tests that are accurately positive, because it's how many people in there have it and showed it versus how many have it and you missed them. The negative predictive value is the bottom row, kind of similar, how many of the people who the tests that are negative, actually are negative, and you've missed and got these false positive results and people who actually don't have the disease. That's so fascinating, because once you got me thinking about this, and I've learned this for every board exam, and then I've kind of forgotten it, and then I have not applied it. And then I started thinking about this, you got me thinking, we need to be using this type of logic in the area they're at with the incidence prevalence. It's got me kind of rethinking how to look at this whole thing.Yeah, and it doesn't this is not something that's unique to COVID testing. This is true of every single test that we do. If you get flu swab if you get a strep test, a culture, everything...Oh a UA for a UTI, I mean you name it, we're you're gonna use this on every single test. as clinicians we tend to move away from this a little bit because well, we're just treating symptoms and we're kind of moving on but this is such an it's such a fun exercise and if you're...if anybody's listening to this, and they've got a child, niece, nephew, friend, anybody who's in med school, this is a great way to learn it. This is not how they teach you in med school, they teach it way harder. That's why it never sinks in.Yeah, well, I've had time to think about it and marinate for a bit. So I just want to finish this without leaving too many slides here. But what I want to do is I want to show now how the disease prevalence how much disease there is in the population that you're testing will affect the positive and negative predictive values. Okay. So to say it a different way, the more prevalent your disease is, the more chance there is of having a true positive, and therefore your positive predictive value will go up. Whereas when you have a lower incidence of disease, it's more likely that the random person you test is negative, so that's going to favor having a better negative predictive value. Okay. So as I said in the beginning sensitivity and specificity, that doesn't change that's inherent to the test. So if I tell you that there's a 10% incidence of disease, and an 80% sensitivity of the test that we're applying, eight people will test positive who have the disease, two who have the disease will be missed and test negative. For the specificity I'm using in this test, an arbitrary value of 94% I'm just telling you that that's the parameter of this test. 90 people because it's a 10% incidence disease 90% don't have it. So 85 will test negative based on a 94% specificity. And five will test positive, even though they don't have it, they're false positives. So looking across here, eight out of 13 people will test positive and have the disease that's a positive predictive value is 62%. That means if you go today, and you go get tested, and it's positive, almost a flip of a coin, if that test is accurate for you, whereas it does a great job of telling you you don't have it if it's negative, so you can feel a lot more confident in that negative study than you can in the positives. When you flip this around, and you increase the disease incidence, and instead you got 20% of people now, the sensitivity and specificity didn't change, you're using the same exact test. So I know that the sensitivity and specificity are 80 and 94 doesn't make a difference.Just to clarify. So to get the sensitivity and specificity it's usually Done where they have the known disease negative known disease positive, they go to a clinical lab and they run it. And then they can show, okay, because that's what's going on right now. Right, they compare it to a gold standard. And that's one of the issues here. We don't have gold standards, but we've got good ideas. And we know that people who are positive with the PCR testing, that's the time to check people because that becomes our gold standard. And those have a very, very high sensitivity and specificity. The assays that we've been using for PCRs, have sensitivity and specificity of 98 and 99%.Of the test, but then we can talk about technique, which is a whole different thing.Which changes, and can lower your sensitivity...part of the problem. So here in this in this example, we're gonna say that 20% of the people that you're testing have the disease process. So now, up here 20% 20 people out of 100 habit 80 don't so now 80% of them 2016 20% is for on the flip side here 75 test negative don't have it five do. So now when you calculate the positive predictive value, because more people around you have it, there's more of a chance a positive will be right. 16 out of 21 increases your positive predictive value to 76%. But the flip side to that, since more people have the disease, there's a slightly lower chance that a negative will catch you appropriately. So now 75 out of 79 give you a negative predictive value of 95%. So to summarize that one more time: the higher the prevalence of the disease, the higher the positive predictive value, the better a positive test indicates true disease. In a lower incidence population, there's less disease there. The test is much better at giving you a true negative result and ruling the test the ruling the disease out for you.Got it. Hope that makes sense. I mean, I think that...Let's, let's play around with a little bit I went ahead and pulled up an Excel spreadsheet. And if you'll let me share real quick I'll do the same thing. Let's play with this. Let's say that there's 100,000 person population. And we can change these parameters. Let's say that it's infected by SARS CoV. There's 2000 not infective. So the prevalence we are now in where are we...Plano? What do you think? What do you think our prevalence will end up being?So tough to say but there's actually data in Dallas, and our prevalence is somewhere between 11 and a half and 12%?Oh, really? Yeah, that is way higher than when I was thinking. It's published data by the Dallas department of health.Okay, so who let's say that there's a 1% prevalence, then what that means is just like you were explaining, if we have a sensitivity of 98%, and a specificity of 99,So a very ideal test.It is the ideal test. And so if you have this, the positive predictive value is literally a flip of a coin. That is, with the best test you can have. That is fascinating with what you just showed. And then of course, the negative predictive value, just like you explained is 100%. So let's say and you're part of the solution, because as we talked about last time, and as we've been working with these companies, we want to be part of the solution. We want to be able to do rapid point of care, IgG IgM tests, and we want to get that data and we want to show it but let's say that here in the state of Texas we are at 12%. That positive predictive value goes to 93% So the more that we know about how many people are infected, the more that we can help these companies with their testing, and the more that we can say things. So I want you to explain this. You have a patient that says, Dr. Akerman, I watched your podcast. And let's assume that we're going to split the difference or whatever, somewhere around 5%. So I got a positive test. What would you tell your coworker, patient friend that did this looking at that?So which tests are we talking about?Oh, we're talking about, I thought I had COVID, two months ago, and I tested IgG positive.Right. So if you've got an antibody test, that's positive, assuming all these characteristics, I'd say there is a very good likelihood you in fact had the disease but if you tested negative, I will tell you almost certainly you haven't had it or been exposed.So let's get back to those tests there. I'll stop my share. The value of doing antibody tests. Everybody on the news is talking, we need to get tested, we need to get tested. nobody's talking what type of tests, the FDA tries to say, sensitivity specificity, you just showed very clearly that it really depends on where you're getting it done. So we'll be able to gather some of this data. And as we start doing this, what are you going to tell your patients that do test positive as we're gathering the data? So that's, that's an ideal. We can play with the numbers. We don't know what the numbers are yet in each segment. So what would you say to that just so that everybody is very clear about what an antibody test is.So right now, the only thing that we can tell you if you're If you have antibodies is whether or not you've been exposed. The assumption is that there's immunity because that's how immunity works for all kinds of viruses. But the The X Factor here, is that what that means for each virus is different. How much do you need for immunity? How long does that immunity last? Can you lose that? Will it wane over time? And these are all the questions that we can't yet answer. So if you're going to get tested, it doesn't help you so much at the moment, because we don't know what it means for immunity, but it helps the population because it helps us better define how prevalent the disease is and that starts helping us then figure out well, when are we going to get closer to herd immunity because we know a certain a certain amount of the population needs to have been exposed. Right?Can you just define herd immunity really quick because that gets thrown around a whole lot by the media. But the reality is herd immunity is a very definitive or it's not a definitive thing. It's a theoretical thing. But...Right, so if you have the disease, and you're walking around, and all these other people around you that you could potentially, infect, that's not going to be great, right? And that's kind of what happened in the beginning, right? People were walking around, they didn't know that they were infected themselves, and therefore able to infect other people. But if enough people walking around you are for lack of a better term at the moment immune so they can't get infected, then the fact that you have the infection isn't as big a deal. And that's what herd immunity is that if enough people around you are immune, your ability to affect the population as a whole goes down. And that's the idea behind immunity and vaccination to create this herd immunity.Yeah, think of it like you're at a bowling alley, there's 12 lanes, 12 people the lane one person has the virus, they give it to lane two, lane two gives it to lane three, lane three gives it to somebody who has been vaccinated. It stops. Lanes 4, 5, 6, 7, 8, 9, 10, 11, 12 do not get this. So that's that's what the herd immunity is. I don't know what the it's based on R0 number, the number of exposed, I think I read someplace, it's if we can get 70% of the US either vaccinated or infected. It basically is wipes out this disease.I'll admit I've heard the same number but I don't know. I don't know the data behind it. But I have seen that quoted.Now you got me questioning data all the time. Now, you know, I'm looking at it's oh my gosh, I'm getting I actually I'm gonna take a break Eric and I worked with Eric today and I was like, dude, can we do a non COVID podcast? Can we do I don't really care what we talked about. Eric brought up, Mike Tyson looks like he's training again. And at 53 he looks like he could just wreck shop. So I'm like, let's talk boxing or something, anything but COVID right now, because the data is just bruhhh, all these non peer reviewed articles that then get chewed up and shredded by statisticians and other doctors. It's, it's hard. It's really hardIt is and it's confusing. And, you know, I think when it comes to all this COVID testing, you know, some of the things you got to remember, as a patient or someone who's looking to get tested, there's tons of tests available now, tons, and all of them have different sensitivities and specificities and because of that, their ability to tell you whether you do or don't have the disease or in the antibody testing, whether they whether you have or haven't been exposed. are gonna vary, right? And many of those tests were recalled already by the FDA and the FDA is starting to crack down on it because they, they sort of opened the gates a little too wide. And because we don't know yet the incidence and prevalence of the disease, it makes it a little more challenging to calculate those positive and negative predictive values. And we know that geography plays a role in this because the incidence changes, right? While it definitely is higher in Dallas than we initially thought, we haven't thankfully gotten anywhere near what the incidence is in New York where in some areas it's gotten over 20%. So the same test might might tell you different things depending on whether you did it in Dallas or whether you did it did it in New York.And you know, you said it best right there that if we do this when we get our tests in because you're an integral part of this, and you're gonna, you're gonna help us try and figure this out tests that we're looking at, will upload to the CDC to help them have real time history. We're gonna have a snapshot of our area, it would be so cool to we're all in this together kind of attitude. Well, let's bring the data in together. I did have a very interesting discussion which you and I have talked about with the manager at our surgery center today, Chris, and he was like, but what do you do if you start testing employees does do you have to shut up? I mean, then all of a sudden get into these ethical, theoretical, where do we go blah blah blah, like you just just go down rabbit holes. All I know is we got to start getting some data and we can start doing it between you and I we can get our patients involved we can get people coming in if you want to get a finger prick and find out if your IgG positive. I know I will feel more comfortable going to the hospital I know I'll feel more comfortable hugging my wife. If we're both IgG positive whether I'm wrong we're just going to learn over time but there's no way to test it.Right and and some of this, you know, information that we're going to gather now, you know, will be available later that we can look back at and reanalyze. So we've got a, we've got to build that data set. And that's kind of the pitch that I would make to our patients and the community at large. You know, if someone says to me right now, should I get tested for antibodies? You know, is there value to it? I would say there is you just have to understand what that value is. And right now, there's a little bit less of a value personally, although there's definitely some, like you just said, but there's a big community impact that we can we can have. Okay, so you always end up with some great little nugget. Say that one more time right now.So, as it stands right now, you'll have some information for yourself. I can't tell you if you're immune. We can tell you if you've been exposed, which is on the mind of many people. I had that illness two months ago, they tested me for flu, it was negative. But now that I know that I know more about COVID why couldn't I have had COVID at that time? This can answer that question. But it can't tell me if I'm immune. But on a population level, it can start telling us what that prevalence of disease is, it then can feed back and make our tests better. Because now we know what the prevalence is. It has ripple effects,This is usually the stuff that's discussed in an academic institution behind ivory tower. Now we're just like, we're all in it people let's all do this. That's, that's what's cool.Yeah, and, you know, two months from now, three months from now, whatever it is, when we find out what immunity means, and what what thresholds we need for immunity, we might be able to look back at this now and say, Well, we've got all these patients that are already tested, and this is the threshold in this test. Maybe these patients are immune and now we can go back and tell them that, you know, sort of remains to be seen, but I would say that there's value in antibody testing, you just have to understand what that value is and I would also suggest that and we've discussed this as part of the parameter that we're going to employ. If a patient has a positive test, you know, partially because we don't know yet how strong that positive predictive value is, and also because IgG starts during the illness, so we don't know if you're a had a disease person or have a disease person, we're going to get, we're going to have all those people get follow up testing immediately for PCR, because if your PCR test is positive, you're actually in the disease starting to get over it. And you're going to you're going to self quarantine, and we're going to let you know and you're not going to expose anyone. And now you're going to know that you had it. And that's going to help you later on, not just now.Yeah, yeah, I know that if I when these tests come in, and I and I get tested, and I'm IgM for instance, calling up the wife and kids and I'm saying see in about three weeks go get a hotel room. Not even coming not even coming home. So...And, you know, I'll go one step ahead of you there and sort of shift gears just a little bit on my soapbox. But, you know, we had discussed a couple recent articles, you know, offline here, one of them being that article in Spain that tested all the health healthcare workers and one of the hospitals where they had really strict PPE. And they found an incidence of the disease that was almost identical to the general incidence they have in population. And it's interesting, because we both we both came to the same conclusion, as did your favorite co host, that it wasn't that the incidence was lower. It was that PPE works. And you know, you can have your own opinions. And I'm not saying there's right or wrong about the economy and all these other things that are going on. But there are ways to meld both of those ideas together. And as we start getting out of our homes and reopening the economy, and we're more available and we have more face time with people, we shouldn't lose sight of that. And these principles that that are working to decrease transmission should still be employed.Yeah, a recent study came out where it looked at ER physicians in Utah and very similar, like the incidence was much lower than you would think. What we're doing works the hand washing the masks everything. So yeah, well, that's awesome. Well, I tell you what, this is a tough topic that nobody's talking about. I appreciate you taking the time to do the PowerPoint. You've got it sorted out in your brain to help thicker brains like me get it kind of figured out. Because when we started realizing that, yes, when I talk to my patients, this is the incident. Six months from now we can say, oh, look, as it turns out, Plano's at 15% or North Texas or whatever, we can say with a certain certainty, this is what it is then. So thanks for helping the companies that we're working with. Thanks for taking the time to do this. And yeah, this is an ever evolving thing. And I think that we're in it, we're part of it, and the beautiful people behind you, and you're seeing there, this is why we're doing a lot of this stuff. SoYeah, I agree. And I would encourage anyone watching these videos, to, to ask us questions. You know, we were, we're guessing based on what we're hearing and what we're seeing what it is, that's confusing, and we can help explain and, you know, disseminate the information there. But if there's specific questions, let us know. That's what we're here for.Absolutely. And as always, please like and share, go to Dr. Akerman's website, go to my website. We got our sponsor Atrantil. We know that a healthy gut leads to a healthy immune system so everyone stay safe. Dr. Akerman once again, thank you for a fantastic point five episode.Thank you.

COVID-19 Files: Ep. 5

Play Episode Listen Later May 5, 2020 66:41

Hello gut check project fans, KBMD health community. This is Eric with your host, Dr. Ken Brown, installment number five COVID file. We're here to, well, you know what, I actually I'm not gonna say what we're here to do because what Brown said he said do you know what I've got in store? And I said no, not all the way he goes good, cuz I'm not gonna tell you soSo this is COVID files number five 4.5 was me and Dr. Akerman and I love our little part time co host Dr. Akerman that is a smart dude. He challenges me to tear apart the literature and it is and we're gonna do more with him because it It allows us to critically eval the literature and he is very academic in his brain and he's an incredible doctor. But the point five is kind of wearing me out every once in a while I just need like a whole number. Really bad at math and, you know, so this episode, we've been so busy doing so many things and we'll get into that right now. But this episode, I realize I'm talking to all my staff. We're talking to patients. And there's an underlying theme here across the board. And it is I'm stressed, I'm worried, how does that affect my gut. And that's what I'm gonna talk about today. We're going to talk about ways to cope and be happy. This is gonna be a fun, you know, self help episode that based on science, always based on science, everything we do is based on science. So that's what I want this to be. I want this to be all about the tricks, tips to stay healthy, to stay healthy and get happy. Because if you're happy, then your other systems like your gut and your immune system are going to be better performing. So you didn't even know that we're going to do this episode, but that's what we're doing today.Yeah, well, you know what, I'm pretty excited about it, and I can tell you one thing just off the top. Once we started doing the COVID recap, we kind of stopped a little bit as we got a little bit more serious and we abandoned a little bit talking of patients I mean our families I'm sorry, family and catching up and stuff like that. I gotta say, I know it's a pandemic and and hearts out to everybody who's suffered but for us personally been home, I got a senior who's graduating, we got to put in a lot more family time. Sophomore kiddo in the house is hilarious, wife and I got a lot more walks and bike rides in. You know, I didn't work for weeks didn't make any money. But at the same time, I feel a little richer just by some of the extra family time.So Stu keeps sending videos. So he's gotten into the whole fact of taking some videos based on doing some stuff with us. And he's got his kids doing stuff. They're doing the Akermann News Network, he's keeping them busy. And I realized I'm like, wait a minute. Both you Eric and Stu, have found a way to remain happy, keep your family engaged. And I'm like, that's what this episode is gonna be about. Because you guys did it intrinsically, you naturally are able to find that and that's what I want to talk about. But more on kind of a science level. So it was very hard to sit there and do some of those episodes when the pandemic was starting. And we're like, hey, Eric, tell me about your family. And it's like and then the next line is 1 million people have coronavirus this many people have died this. We're getting away from that a little bit now, because we realized we were in a pandemic, we're in this thing, but now it's time to realize this may be a very slow exit from here and what you did and bracing your kids and what Stu has done, where he sat with his family, and they've, he's turned little movie stars out of his daughters and they're, he's absolutely screwed because they're gonna want to go to acting school now and all this other stuff. But that is the kind of stuff because when I sit with my employees that are stressed to the hilt single moms, they're like, I'm waking up with panic attacks. Dr. Brown, how can I do something and so I was, you know, we're starting to open up the economy here in Texas or open up, your governor Abbott's letting more people get around each other. Now I'm getting all these patients calling me going I'm terrified. I have this disease. My employer now wants me to go back. How do I have to go back but I'm having panic attacks. What do I do? Well, let's do a podcast on that. That's what I thought.This, to me, I think it'd be a great idea to do exactly that because inevitably we've got to move on. We can't sit around and you just don't want to get lost in watching the counts on television or keeping up with the next the next latest fad on what was one of the crazy things I heard someone saying using a hairdryer shoving that up your nose to blast away Coronavirus? I mean, we need to be practical.Can I stop you right there? Is that seriously a fad? Because I've been doing that.Well, I want to let you know that your nose hairs are...they're beautiful.I know at the very least I've not been clipping them so at least saves them back to a presentable level.Yeah, I think we're gonna have I think we're gonna have some new fads come out of this thing. I think that some of the 70s hairstyles are going to come back. I haven't had a haircut...Oh my gosh, I am absolutely loving the crazy hair. I mean, this is awesome. My kids. Well, we'll get into it. But basically you do these workouts you get sweaty and you realize how long your hair is. I'm just like, oh, this is awesome.Well, you know, I've seen more and more people who've been wearing the mask in public Of course over time. I'm kind of curious if there's are people who generally snack it while they while they walk or why they do things. But now that they're in public, they had this maybe they'll who knows maybe maybe maybe weight loss will be inevitable because people will have a social covering where...There's all kinds of things. So one of the things I want to try with this episode so that people are looking at this and go every time you do this get so bogged down with science, and it's an hour. I talked to Stu about that. He's like, man, I love doing this, but are we capturing the audience? I'm like, I don't know. Let's try and do a little quicker and see what happens. I don't know. I personally just like sharing information and being totally honest about this this is not about trying to develop it. I mean I want my audience to be happy and we're gaining a significant amount of traction but in this particular case, let's see if we can not get too off track because you and I I do you're always perfect but I always get off track so It's kind of hard but we'll we'll see...thank you though for...So I'm gonna throw this out to you tell me something a little personal now that we're not going to get too heavy what's going on with the fam?Fam is doing great. Gage is still bracing himself they he's headed up to Texas Tech for this fall will be his, his first year in college. The orientation was moved to virtual orientation they have to do that. The level apparently trending in Lubbock currently is as it is apparently flattening out and for right now coming back down. So he'll have an online virtual orientation. Mac is is wrapping up his sophomore year at school. And he just left the house to do a bike ride and for how far who knows? Or who cares. He in his in his brother have taken off and traded out their their terms to to get some bike riding in and that's what they've been doing. Marie's remained busy for her in her business, social media is people still keep up like that. So she actually saw a boom in business over time. And then...That's awesome. Yeah. And actually, I went to work today for the first time. I didn't think it was the first time in seven weeks it was nice.Did the patient flop around and scream the whole time and be like, I'm not out.Yeah, it was a little bit of a learning curve to remember how some of the buttons work but it wasn't too bad. Well so family's doing great. We also have been doing pretty well during this whole quarantine. We've small setback, which is where the unrefined bakery comes in. Unfortunately, Loida was enjoying playing around with the kids a little bit and she hurt herself. And so we had to add a little small setback on that, but she's doing awesome and...about it and won't be able to drive for about six weeks, but we're getting through it. I thought it was really cool. I walked into the garage and Lucas was with his computer with six other of some of the top level tennis players with a trainer there. And he's watching all of them and he's training them and he's saying they're they're all in different parts of the country. It's zoom thing. And Lucas is you know, I just took a picture of it. I thought that was just so beautiful that all the all these kids are still working out the trainer still riding them. And then I go back inside and my daughter is turned it so Lucas is like doing this virtual athlete thing. And Carla is sitting on the couch. She is the world's greatest quarantine person. She was like cross stitching and becoming like a old grandma. I'm gonna just we call her. It's really funny. So she is having no problems just sort of chillin with the school online school and all that. Yeah, so and then me personally, you and I have been busy I mean levels of busy that I have never done. For instance I did wellness mama podcast shout out to wellness mama and their team. Wow, that was cool.Nice. DefinitelyDid that one and then you and I've been doing some other cool stuff you want to tell everybody about that?Just tons of research. I mean there's there's always been the idea of what you wanted to do on researching polyphenols or even just other natural compounds and how they can make a difference. And ultimately, we were just forced into a lot of free time that we just didn't know that we were going to have that we needed to dedicate to work and keep up with different things but it just turned into immense research, thrusting us all the way to just yesterday. We just received our first sample of what a point of care antibody test.Oh so because of all the stuff that we've been doing and shout out to Angie Cook I meanAngie Cook, without question...She's working as hard as we are and stuff yeah so because of this we have access to unique people that reach out to us like people that have a legit SARS CoV2 antibody test right there and what this is what is unique about this is there's a lot of bad press going on right now. But these guys teamed up with a software company called remedy and what those two QR scans are that's unlike anything else. So you can imagine it comes with a kit like this, I just poke a finger and then we can determine if you're IgG IgM positive, go back to COVID 4.5 to learn what that means, but then we get it scans straight to the CDC and that is a game changer and because of all the work that we've been doing and the contacts that you know, we are in a position to work with a company that may frame what this country is going to do when they come back to work. So I'm super excited. And we're always working really hard to do this. And there's pros and cons to it. Please listen to 4.5. That's what I love about Stu. He's a scientist. And he says, And me, I say, we will we have to be the people that are going to help develop some of this data that everybody else can do, somebody has to jump over the fence. And traditionally, you and I have been fence jumpers. And sometimes we get bit sometimes we do right. So...You know who else is fence jumpers, and really, really a lot of fun is going to be those that are on or that are part of the patient base that you've had that make up most of KBMD health that watch this show, because they've always been so, so energized of wanting to get involved, and this is going to be yet another opportunity to do exactly that. HopefullyWhen we get these and when we're cool with this, and when we're ready to do this, we'll do a zoom with my staff, we will all have this, we'll do a point of care. They'll all be in the office. So it is at an office, we'll do a thing. All you do is pop this off, prick your finger, put it in, wait 10 minutes, and then it shows if you're IgM or IgG positive. We don't know yet if the IgG positive makes you immune. We're hoping. SARSCoV1 in 2003-they were immune. But if we can start being part of the solution, that's the deal, Eric, is that we're trying to get past this. We're working with scientists all around the world. We've had zoom calls with people at the same time. I mean, technology's amazing. And that's what we're going to talk about on this show. Is that yes, we have this thing going on, but we also have all this crazy technology. We had a zoom call with like 20 people We had people in Argentina, we had people in Spain, we had people in Italy, we had all these people in United States and everybody is sharing knowledge. They're just dumping it there. What can you do for this? How do we set up a protocol? How is this and everybody on that call had a little piece of the puzzle that led to a protocol that now the Argentinians and the Italians are having a protocol using polyphenols to potentially see if it can help COVID-19 and it was accepted by both Ministries of Health. They would like us to try and do something in the United States. It is just an honor. That, yes, my job stopped. And I became busier and made zero money. But I'm thankful that I have people like Angie cook on our team. I'm thankful that we have the rest of the team on KBS, Brandy, Anthony, Mike, Chuck, to trust us that where we're heading is an incredible place. And the ultimate goal is that we may make a difference moving forward, might not, but we've got some science to back us. So that's what I want to talk about today. How do we have science to back our mood? So that's where we're at.Yeah, I love it. I love everything about it. And the cool thing is, is if we can be a part of even just the information gathering, you're not gonna get anywhere without information. And the coolest part is we've got so many willing participants who have said I would like to partake in that. Great, I want to be a part of it too. So it'll be a lot of fun. You mean like on KB MD health Instagram, where I asked Paul to post your picture holding it and then you've been bombarded by instant messages.They wanted to know how they can come and get their hands on a on antibody test and and I think everybody should call Ryan Frye. So if you're a friend of mine, you should call Ryan Frye. That's exactly you should call. Alright, so let's let's jump into this because the ultimate thing is I want to make sure that if anybody's having any stressful times over this, we're going to talk about a few things and I've been looking at it I've always tried to talk, or I've always tried to teach myself a bunch of different things to try and control my anxious brain because I run it a little higher anxiety level than most people I would say. And time like this would be overwhelming if I didn't have techniques that I've tried to employ. And so some of the things I've been turned on to somebody called Laurie Santos, who has a podcast but she also has a Yale courses, you look at our videos, and it's all based on science. I'm a big fan of reading a stoic philosophy books like Ryan Holiday, and then ultimately trying to stay logical and finding techniques to do this. So that's what I'm talking about today. We all have setbacks. We all have things that happened to us, but this particular period has turned everything upside down. People are feeling overwhelmed, they're angry, they're alone. So let's do this podcast on some tips, tricks to reframe the perspective and gain control over your own brain. That's what I want this one to be about. Let's try it. Let's see what happens.Exactly. Let's try. Alright, so I wanted to do it in a couple, three different broad categories have been successful for me, right? So I'm not a psychologist, I'm not a psychiatrist. I just want to tell everybody what's what's kind of helped me a little bit. Okay, that's all that's all this is. So number one, learning from the Greek stoics. Now, I've mentioned a few times on the podcast that I'll reference Ryan Holiday in the daily stoic and things like that Ryan Holiday's an author who has been on he's getting written multiple books. He's written the book, the obstacle is the way and the daily stoic. I have the daily stoic where next to my bed where when I wake up, I try and read something and start my day off that way. There's a guy named Bill Irvine who wrote a really cool book called the stoics challenge a philosophers guide to becoming tougher, calmer and more resilient. Now in this time, we're having to postpone things and we're having to, we got a text from Nick where he's gonna be married, so are you gonna be able to get married. Do you make a plan? Do you do this? Do you have to postpone the wedding? And that's just one stressor for somebody that's going to get married. Now what about the guy that loses his job or the man or woman that loses their job? When Loida got hurt, in the hospital, they don't allow loved ones. And, you know, she's, she's tough, she's gonna be fine. She's in shape. But what about the people that are dying of cancer that can't see their loved ones because of social distancing? I just started thinking of all that, but about all of that. And then the stoic philosophy is not about ignoring the emotion. It is about skillfully avoiding negative emotions. So a lot of people think that stoics just don't feel anything. That's not the, that's not the thing. It's about avoiding the negative emotions. We have a lot more control than we think and ultimately, you've heard this a ton of times it's been said, since we've been on Earth. Worrying about something that is out of your control is a waste of time. But we do it all the time. I do it all the time. I mean, it is so hard. And then I started thinking about that. And I remember jack aloka, the PhD that is in our group who I admire so much. He keeps referring to when your reptilian brain takes over. And what he means by that is when your logical brain gets overwritten by the reptilian brain, we have our reptilian brain, our brain stem, which tells us and keeps us from getting killed. Sometimes it becomes a wrestling match between your prefrontal cortex trying to tell you hey, dude, it's all good. And your reptilian brain going no, it's not we're gonna die. We gotta run right now. And it becomes this wrestling match. And so it's this battle between the evolved brain and where we've come from maybe 1000 years from now the reptilian brain becomes nothing. But right now we still have to deal with it. In other words, that's the fight or flight. So if you're listening to this and you're like, yeah, I'm stressed out, it's because your fight or flight is taking over. So let's talk about how we can maybe get the reptilian brain to calm down a little bit and let your logical brain kick in. Are you following me?Yeah I'm totally following you.Alright, so we have about five seconds, generally speaking, to reframe any situation that you're in. So if you get angry, then you have about five seconds to get control. So for instance, you're working in your garage, drop a hammer hits your toe, what do you do, Eric?First thing is, wow. probably say words I wouldn't say on our showAnd you should, that's the cool thing. You can do that for five seconds.I'm not gonna stop, I'm gonna do it. And younger me I think would be kind of miffed older me now I'm I was looking at...and I kind of assess the situation on how did it fall? I mean immediately because I want to find out if it's going to keep falling or something else is coming. That's awesome. Yeah, so that is your cerebral cortex suppressing the reptilian brain that's awesome.I hope that happens that when I was younger, younger me didn't do that younger me was very emotional getting kind of upset and want to move everything out of the way. Taking it out on a lot of inanimate objects, because it probably the desk is friends with other hammers that also have it in for my toe. And but now it's now it's far more logical I don't I it's, it's probably something neglectful that I did. And if not, I probably won't put myself in that situation anymore.See, you automatically have these skills. So you know, like think about road rage and stuff something happens, escalates. Now you're in a different situation. Now you're in a worse situation. There's a Buddhist philosophy that if you get hit with one arrow, then you ask yourself is getting hit with one arrow bad? Yes, it is, is two and three arrows worse? Yes, it is. Typically the second and third arrow are under our control. So you what you just said is fantastic. Younger you would have thrown the hammer through the window. Now you gotta fix the damn window, you hit the cat, the neighbor's cat. now you got to deal with that. So that is one of those things. So it's like this is training for life. I love that you literally have developed these skills without ever thinking them. You said a younger me would have done this, but me now looks for reason.Oh, yeah. Younger me was was not very well equipped to handle hammertoe.Alright, so here's the two techniques. So if you're listening, if somebody's going, I don't really care how Eric handles dropping a hammer my toe because I still throw the hammer. Here's the two techniques. Stoic philosophers describe two very common techniques to help you. The first one is called framing. And framing is when a situation happens give yourself five seconds to throw those curse words out to be the, the let the reptilian brain out there, but you'll be five seconds because more than that, then it becomes an emotion that you can't control. Five seconds then frame it immediately when something happens. And there's two very common frames and I'm not a stoic philosopher, obviously, but these are the ones that I use. Remember, this is how I try and control my my emotions. One is comedic framing. So if something happens, figure a way that it's kind of funny. Even if it's not you, it's somebody else looking at it that'd be pretty funny if somebody else saw it. If I saw Eric accidentally drop a hammer on his toe. I would be like, dude, you're okay. And you're like, yea, like, dude, you're so dumb you had like Vaseline on your hands and grabbed the hammer and you swung it, then it becomes funny immediately. Doing a comedic frame helps with that. And then the other one, which is much more in line with my personality, it's easier for me to do. It's called a story timeline. So basically, we're in a situation so the comedic framing is really good for an immediate of that hammer drops on your toe, you figure out how to fix that. You figure out how to make it funny for yourself. But we're in a pandemic. If you're in a war. If you're in a period, then this you can't just make a joke of it and move on and be logical. And one of the things that the stoics have done is that they say focus on the story timeline. How will I be able to tell my grandchild about this event that's going on right now. I want to be able to on the other side of this, how will I be perceived? Once again with my office when we sat and had a meeting, we're like, do we furlough people. And Dr. Akerman said, before we even talk about that, how do we want to be perceived when this thing on the other side, we want to be known as bosses that treated their employees well, so let's start with that, and work our way back. This is exactly what this is. This is how, how will I sit there and tell my grandkids, how I handled the war, the Stockholm paradox and in the book, good to great that you and I are reading in business, he was a prisoner of war for seven years. And he said the people that died were the ultimate optimists. He was an optimist, but a realist. In other words, I know I'm gonna get out of here, eventually. How am I going to tell my children about this story. That brings a certain amount of distance. And it allows you to have control of where it is. So when you want to give up...when you want to say I want to panic, just go, how will I be telling my grandchild...because I will get through this. How do I tell my 12 year old grandchild, that I went through a pandemic, and I lost my job, and I had friends that died. But this is what I did. And I kept going. So the stoics, use two different framings. If it's a short term, use comedic if we're going to be in it for a battle, a war, frame it so that you, you describe who you are older, telling your children that, which I thought was pretty cool. What's your thoughts on that?Actually, that is kind of transcendent to a bunch of different scenarios. I mean, I can remember before, before we had kids, right? You just thought there's the idea the concept of kids these little people that you have no idea you don't think of them really necessarily as a piece of you because they don't exist yet. They're just it's a concept. I'm a kid, I'm a kid to my parents, right? So then suddenly you have them and you go kind of through a little bit. I think most people do a little bit of a panic phase, like, what do I do with this very, very fragile thing? Then when the interaction begins, you kind of learn a little bit about each other. You quickly realize that you're creating memories. And I thought back to my parents, and how I wanted to be able to tell my kids how cool my parents were to me. But I started thinking, I want them to say how good of a dad I am to them.So you automatically so you you're you're a very funny guy. So you automatically comedically frame things and you automatically have this story timeline. And you did it with two generations. That's awesome. Think about my dad. How I was perceived by that? I want my kids to do this. You do it naturally. That may be one of the reasons why you're you're perpetually happy.I don't know, I guess so my, my parents were both kind of like that they can they can both tell stories about their families from two or three generations back as if they were almost there. And obviously they weren't right. But they and it's usually the funny stories that make its way up. Right. No. And who wants to tell the the bummers? They if those people are part of this narrative they usually probably don't show up that much. But it make yeah, I don't know. It's kind of weird. But you you begin to frame things around the idea of what do I want them to carry forward because that ultimately will shape the way that you're handling the situation of this.100% so that comes very natural to you. Now I'm going to tell you one that probably is not natural to you, but is intrinsic to me, which is interesting. We've both had some loss, and for whatever reason, this particular practice grounds me and the stoics call it practice negativism. So what you just described was this positive thing I want to create this thing. It's much harder to think about, but when you get really down on something, or if you get or if you're starting to get down on something, then imagine that it's not there and what your life would be, but not like imagine a little bit like get deep into it. So imagine what it would be like if my spouse died. And just go, no, not like, but like, think about like, it's a form of meditation is what it is. So you stop for a few moments and you think about this. I hate my job. What would it be like if I was unemployed? What would it be like if I was broke and had no job? I'm really upset at my spouse. What would it be like if your spouse was deceased, and that person did not exist? And it's an interesting thing because what it does, if you, if you really think about it, then when you see your spouse, you're just like, loving you like because every day could be the last day sort of philosophy. And you this is something that a lot of people don't like, but for some reason it resonates with me because I've had loss. And I sometimes think, you know, the job was tough today, but what if I didn't have a job? And oh shit COVID showed up, but I didn't have a job. Now I'm like, I miss my job. I miss it. I want to go back.No, that that is I don't, I won't say I have never done that. But you're right. That does not come quite naturally to me to just basically you're saying to find something that's bothering me today and just okay, well, now it doesn't exist at all. Now, where are you?Yeah, now Where are you? Cuz you'd be surprised because a lot of times that person that you think is annoying is really important in your life. That job that you are frustrated with is necessary in your life. Regardless, the goal here is to reframe so that you can take control, even if you don't agree with it. All it is taking a step back and going, these emotions are making me stressed, anxious, and so on. So that I'm gonna take a step back and I'm gonna reframe the stoics call this reframing so that you can control that. So that is the stoic philosophy of how to do this. And, like, the stoic philosophy that I have garnered, that helps me.Sure. That makes sense, though.And you're already doing it, which is interesting.What can I say?Yeah. All right. So one of the things that a few employees approached me and there's some people that are, well, they're having straight up panic attacks, straight up panic attacks right now people are flipping out and so I want to talk about why panic and anxiety is bad and as somebody who probably has a mild form? Or it could be a horrible form of panic disorder, but I have always been on the curve of having more anxiety than just being a chill chill person, let's put it that way. I think you are a little more chill. I'm a little more on the uptight, anxious side. And so I want to talk about that, like why panic and anxiety serve zero purpose.Right? And they, and they do, I don't, I really don't know what to make of them. It's not something that's really not something I've ever been accused of is being overly anxious or panicky, or someone who gets unnecessarily worked up. That's not really my thing. I don't know.Yeah. And that's a wonderful thing. And I was talking with one of our employees on Wednesday, and she was telling me that she has panic attacks and her daughter is starting to have panic attacks. And she would I loved it because she's like, I'll handle mine. But watching my daughter have a panic attack, I need to find some ways to get her out of it. So that's how come I started thinking about this. I'm like, I'm gonna do a podcast on this and we're gonnaAnd I believe they're legitimate. No doubt it's it's, uh, I just wish I wish I had more sympathy, not only empathy for the position because I don't really, I don't know. I think that when I feel something kind of getting a little out of control, then I well, my dad got sick. I knew what was going to end up happening. But I prepared myself for the bad parts of what was happening with my dad is he was dying from cancer. And I compartmentalized the bad part of being the biology of cancer, and how he couldn't out run him and when we're, nobody would outrun it really where he was. The flip of it was is it left me with all the good parts which were just hanging out with him and talking about the times that we had together the memories and just kind of reliving some things together, which was great. But I didn't, I didn't associate my time or my conversations with him while just constantly thinking about his cancer, we, we just talked about the fun shit that we had done. So I truly believe that your father had that framing mechanism in place because I know that he was in pain, but I know that he probably met with you and said, I want to be remembered like this. I don't want to be remembered in certain ways. So when you would tell me about that, even in the last few days, you guys had a great relationship. And he grew up remembering somebody else he grew up remembering tell the story so it can be told again. So I think that's cool. But for somebody that doesn't have this and if you have this I feel for you because been there. I looked up a guy named Ethan Cross and He is an expert in this and he is an expert in how emotion regulates planning. So we're in an era where a lot of people are experiencing anxiety that they've never experienced before. And it's new to them. So when you have anxiety what happens is you will over focus on something and have poor decision making. You're less logical. It's one of the reasons why everyone else brought bought all the toilet paper. I mean, what the heck, that was crazy. There's just no reason for that. We don't have a shortage of it they're there. But they didn't sit there and think, oh, in the pantry, I'm lacking this and this and this. They panicked, they went there. And this is what happens. When you're over focused on a threat there's no mental space to work on a higher level. So if you're all which is good, if you're being chased by a saber toothed tiger, it's bad if the threat's not leaving. Does that make sense?100% I mean, so, in an instant, it's okay to have quick panic. But but prolonged panic is dangerous. I agree with that.Prolonged panic. Prolonged anxiety does one thing and you know this and we've talked about this on other shows. It's the fight or flight system, which means your sympathetic nervous system kicks in when the sympathetic nervous system kicks in, that leads to chronic inflammation, chronic inflammation leads to biological systems shutting down that leads to your immune system wearing out so if there's anything you're gonna get out of this, it's that when you're panicked, you're predisposing yourself to the things that you're panicked about.What do you think that what do you think the correlation then would be between somebody who's experiencing chronic chronic anxiety or I don't know, frequent panic attacks and a lack of sleep? I mean, It's all of the above. So that's what this is about. That's what I want to talk about is as somebody who's had significant anxiety, I mean, I grew up as a stutterer. I had I answered a question on a Reddit thing where somebody said, If anybody's ever stuttered, what have you, what would you recommend? And I was like I, I did for the first 20 years of my life, and I worked through it, I tried to do it. And my anxiety led to stuttering. And then I realized I can, I will never stop stuttering unless I get control of the anxiety. And the anxiety is a thing because ultimately, you have to have emotional regulation. Everybody's flipping out right now you have to have the ability to align how you feel to how you want to feel. So if you're panicking, you need to have the skills to say, I'm panicking. I want to be in a better place. You're not trying to turn it off. You're just trying to reign it in. Like right now, it's almost impossible to shut it off completely. You can't be that like we were talking earlier about the stoics. They're not turning off their emotions. What you're doing is you're trying to make sense of it. What this is doing is having some skills to try and have emotional regulation. Because having some anxiety is important. If we didn't have some anxiety, we would have zero social distancing. And we would have a pandemic beyond any proportion. And we know this is bigger than anything that's ever happened in most people's lifetimes. So having some anxiety is important. It helps us help each other. But I want to talk about two really cool techniques. I'm going to call these brain hacks backed by science. So these brain hacks backed by science. So the first one that this guy Ethan Cross has written about is psychological distancing. And I think this is super cool. Because you and I do it to each other all the time. When we work together. We show up we're like, hey man, what would you do with this? And it's a problem that I can't fix. You're out that I throw it to you. You shopped work, and you're like, I'm kind of torn with this MAC gauge this what school blah, blah, whatever whatever thing that you're emotionally tied to, you go to a third person, and you're trying to get a different perspective. And so it's that it's that, that third person perspective, because the person you're talking to, essentially is somebody that doesn't have or they don't have the emotional baggage associated with it. So going back to the original thing, when you're anxious, you can't use your full prefrontal cortex to make a decision. Part of your reptilian brain is going, ah, I don't want my son to go to the wrong school. Ah, I want this ah, or anything, you know, everything that you're emotional about. So you go to a friend and you go, oh, I never thought of it that way. That's odd. What what's what key thing applies to everyone all over the place. planet who, who ultimately will go and get advice on it, and that is finances, financial advice, our emotion is tied up with our belongings, our ownings, our homes are things that we want to invest in our vacations, etc. But the reason why over more and more time financial advisors have become such a great person to help us is because they can look at your finances without bias without emotion. And they can help you actually probably achieve more of what you want, actually, emotionally by showing you logically, how to move and utilize the money that you're bringing in. That's a really cool thing that you just highlighted there on how you wouldthrow that to a third person. That makes sense to me. It makes total sense, right? So they've done incredible studies on this. So this guy Ethan Cross is the head of the emotion regulation department at University of Michigan, and they've done lots of studies that you're not going to believe this. When you mentally refer to yourself in the third person, you can be more objective. They did studies where they took people and they said, we want you to apply for your dream job. And you're going to be graded, you're going to be evaluated by a team of judges. But they took half the people and they said, I, they had no idea what they were doing. They signed up for a volunteer thing. Apparently, public speaking is more stressful than pain. So like you don't shock people or things like that. So they were, they said, you have 10 minutes to prepare a public speech. You're going to go in front of judges, you're going to be filmed, and you're going to be critiqued on this. They took half of them and they said we want you to start with I am going to give a speech which will determine the course of my life. The other half. Eric is going to give a speech or Ken is going to give a speech you refer to yourself in the third person. All right, Ken, you're going to give a speech. It's going to change your life. Let's see if we can do this. Shockingly, they did an incredible job when you can separate yourself and refer to yourself in the third person. So even though you go to somebody else, psychologically, linguistically, when you say Ken, how am I going to handle this COVID crisis? Okay, Ken, you're on call. You just got 10 consults. We got this using these words. internally. Don't say it out loud. Because people will find you weird that's the only thing What are you doing here? I'm here to watch Eric do some stuff. He's pretty good guy. Yeah, just out loud. Be like Ken's scoping like a beast now watch Ken take this polyp out. Yeah, no, yeah, don't do that. But it is certainly a technique. And so there's something that's kind of cool about that. Where it you separate yourself and you take control of your emotions. I am not experiencing this. Ken you're going through this problem? How are you going to figure it out? It's a very unique psychological thing that has been proven in multiple studies. So little hack. When I start when things start getting way out of control, mentally, it's all right Ken, we're sitting in this podcast and this thing is shitting the bed. What do we do now?No I do I find that to be useful. It makes sense to me, but I won't say it out loud kind of like you recommended I think.Yeah please don't but you can actually do that with like, he was talking about like in children's learning. If you have a child that struggles with doing homework and stuff, don't go up to them and say, why aren't you able to do this? Just go hey, how would Batman handle this?Let me ask you a question. So when when you were an intern and you are working, I know that you did er work do you remember how you watched yourself run your first code? Remember that?Oh yes, yeah, totally.I kind of remember getting into a system where it wasn't that I wasn't present, but it felt like I was watching myself do the training right? And systematically just calling for the things just as I had learned, but and really more of how I memorize to go through the own algorithm they taught us to do and so when I asked for things where I needed someone to chart something, or if we needed to met or we needed to change team members or anything else like that, it's a really calm conversation. It's not really heightened. It's not screened, I think we've both been a part of some, some codes that have not together but codes to get that have been kind of in disarray or kind of crazy. Yeah, those those are not desirable. you need you need to be able to have someone kind of run the code that knows what the next part is, is being that part or playing that role for I kind of just saw myself doing it rather than I'm doing it. Does that make sense?Oh it makes total sense. My first code at the VA when I was an intern code happened. A little voice next to me was just like, you know, you got this stay calm. It's time for Epi. All right, let's go ahead and do this. And let's do that. And I thought it was me. But it was the it was the senior nurse next to me the whole time. I was like, my inner voice is awesome. But basically, it was a cool, established VA nurse going do epi do this.Was it a guy or a girl?No, it was a girl. It was Janice and she was awesome. And I learned early on that they knew way more than I did. So I just did what they said.Well I didn't know if you thought that you just had a really sexy voice to...Alright. So to make sure that we stay within the 30 minute time zone here, we got to keep moving. All right. So technique number two, is temporal distancing. We kind of heard about that last time the stoics use this, basically don't think how you feel now. But how will you feel two years from now? I mean, we're in this COVID crisis, right? If I look at you and Eric, I'm like, Eric, we're gonna get through this. There's going to be vaccines, there's going to be herd immunity. There's gonna be antibody testing. We're gonna be able to fix that. You're gonna be there are gonna be answers. Yeah, there's going to be answers. The stoats took it to a new level where they said, think about the next generation and how you're going to tell your grandchild. Ethan Cross is talking about no, just think about it, like in two years from now. So you can integrate the both so right now what I'm telling myself is, Ken we're going to get through this in two years we will be stronger. So it is a we being all of us are going to be part of this. Ken, I'm talking to myself objectively and we know that this language is a conduit to control your emotions. The language is a conduit to control your emotions. So my final hack on how to do this, so we went through the stoic philosophy, we went to the Ethan cross, how to do these linguistic things in your head? Well, then I put it all together. And I realized, you know that I've been trying to have a prior to all this whenever we when I actually had free time, when I was working full time and had more time. I tried to teach myself some neuro linguistic programming NLP, right, and that's what Tony Robbins does. That's what some of these great motivational speakers do. And one of the things is that if you are prone to panic attacks, then you have the ability to linguistically train your brain to bring yourself back down and there is a technique called anchoring. Do you know what anchoring is? Did we ever talk about that?I do remember, the gentleman that visited with us in Arizona briefly talked about that, but that honestly, I don't know anymore. Oh, wait, wait. It's an emotion that you tie back to a sensation or something like that, like you pinch something when something occurs or maybe you make tap yourself on a knee. It's like a Pavlovian thing with the...something is that right?Look at the big brain on Eric. Yes, absolutely. So as it turns out, it and you can do this if you're listening to this or any of my panic attack listeners. You this is another slightly meditative technique, but it is a mind training technique. And so if you can think about an emotion so Eric, tell me about a happy memory. Oh, tell you about a happy memory. A goodness gracious. I remember. I mean a deeply emotional happ...like when you think about it, you just immediately just go, man, that was awesome. Yellowstone. I mean, you've you've told me so many stories.Like I don't want to give too much credence to one of...the young one I can still remember without question when I when my dad and my mom got me a drum set. My dad taught me how to play drums and then one, one Christmas Day, then I had one and I was pumped. And I knew that I was tying myself to that instrument forever. And I loved that moment.So if you practice and you stop and meditate on that moment, and what I mean by meditate, it's not like a difficult thing. Just stop, cut everything out and think about it. And then put a physical tie to it and I'm not an NLP specialist, but this is what I've done. So when I want to get amped up and get happy, I hit my chest, which is what I believe Tony Robbins does. So I have a particular memory in my head where when I'm want to get myself revved up, you're going to go on stage, you're gonna give a speech, you're going to do something where you want to be really revved up. I hit myself in that emotion because I've practiced it allows me to amp up my my mood immediately no matter what I'm in, because you've trained your brain to do that. So when you sit there and think about this, and you just go okay, I'm a little down now, I want to be up, then you they talk about anything, anything you do that is not too obvious. So the neuro linguistic people talk about touching their fingers together. They talk about that I hit myself because I want to make it obvious to me. So when I want to amp up, I hit here and my memory is of a very exciting memory. That's called anchoring. And if you want to calm down, then you think of another memory that is very tranquil. So my memory when I want to calm down is me and my family in Barcelona, Spain, eating at a Michelin star rated restaurant with young kids and we're killing it. And every single time I get super stressed, and I just think, oh my god, it's overwhelming. I can't do this. I rub my thigh and I just see my family in front of me. And we're eating this incredible meal. And we're in Barcelona, Spain. And it's really hard to be anxious and calm at the same time. And if I'm not there again, so that's what anchoring technique is. So it is something that has to be practiced. Yeah, I'm not saying anchoring. Like wolf of Wallstreet, like, umbaumba, that was a little too much anchoring with some. I just realized I was hitting my chest and I was like, that's not a little Matthew McConaughey right there. I need to step it down a bit. Not that I mean anchoring in a different way, where like I rub that. So if you're anxious and prone to panic, there's this technique called anchoring. And if you need it now, then there's these, these are the things that I use physically in moments that I try to make sure that if I'm aware of it, and then there's the whole breathing techniques, meditation, exercise, emotional gratitude, all these other things that are out there. But those are all practices. Those are all things that seemed general. What I wanted to do today was say, this is what I do to try and stay calm that anybody can do. And that's kind of where I'm at with it. And what I want the next episode to be is for our soldiers, our frontline workers. Oh, yeah.Because the next episode will be about long term safety. I want to dedicate the next episode to our frontline workers. Eric, would you please describe what we're doing for our frontline workers right now,Man, it's as this is incredibly exciting. So just huge kudos to to you Ken because for a really really long time, you've known the benefits of polyphenols. And we've had all this research just kind of sitting on the fringe and huge thanks also to Angie for always giving us new updates. But the the pandemic just thrust us right into the middle of we've got to start swimming through this information. And then as you began to assemble it, suddenly with the help of of Angie really digging through and finding some cool stuff. We found that the polyphenols themselves actually function as great natural antivirals and anti microbials. And it just so happens that we have polyphenols and Atrantil and it just so happens that we want to give back to people that are fighting hard for all of us. So we have a pilot program where for the people that are working in a role where they happen to be a frontline worker or frontline healthcare worker, they can simply go to Atrantil.com/frontline, let us know that. And then they tell us where they work. And we'll send them a complimentary bottle for a month. But even more than that, keep them up to date with the latest in research out applies to them, and then hopefully begin to recruit some other healthcare institutions. To help us spread this it's this is not an opportunity for us to to make money this is an opportunity for us to hopefully keep healthcare workers available to us, not just for COVID if it happens to come back, but in the future, when the next pandemic occurs when the next new virus makes its debut. We want to see if we can't make a difference and help people naturally and what better way then to arm the people they will take care of the sick.Yeah, absolutely. And once again, we as we always stayed on this show this, this show is not about to give medical advice. We're not here to tell you what to do. Talk to your doctor about everything. This is a show of information. And what we're trying to say here is we are not making any claims. We are not saying that we can do anything but the science speaks for itself. We are talking about the class of molecules called polyphenols. And these polyphenols have been shown to improve immunity. They've been shown to improve gut health. They've been shown to decrease inflammation they've been shown to mitigate cytokine release all these other things, which is why we sat there as a team, the KBS research team that developed Atrantil and I was very honored to be part of a company that I'm very honored to be part of an office that didn't furlough anybody. I'm very honored to be part of a company that said we are willing to front the costs on this and help the frontline workers. Because I'm on it. My kids are on it. My staff is on it. And we're I I have a motral obligation to say why and the you know, the reason why is because we've got science that backs it. We're gonna have this polyphenol page that will actually show it. So, next episode is going to be dedicated to the frontline workers and we're going to talk about cool things like what's your decontamination routine? I'm asking everybody so if you know anybody that is in healthcare or if you watch this show, hit us up. Tell me what your decontamination routine is. I know that Laura your your partner crna she's got a cool thing which comes in the garage and she's got a robe there and she gets naked, puts the robe on, puts the clothes in a bag, shoves it in the wash, doesn't hug her kids goes to the goes to the shower decontaminates and does this and there's a whole process a decontamination station. We want to put everybody's best advice together. Next episode will be our frontline worker heroes episode. How do we help you to help everyone else because you guys are amazing. Oh, shoot, Eric, you're amazing. You're a frontline worker, Look at you.Yeah, I don't want to take credit like that. I mean, because because Laura still spins significant time in the hospital system also. And full disclosure, I really don't have to do that that much anymore. I did for a long time and you know, avenue different avenues take us different places and then it's number one, thank you, but you actually put in a little bit more time in the hospital. I don't want to take credit away from those who are actually getting just, you know, much much more exposure and braving much choppier waters than myself.Oh dude, Stu and I were talking about that, you know, he's from New York and he's got, you know, when his friends do rotations and they think they might be exposed, they don't go home to their spouses, they go get a hotel room. That's brutal. I mean, that's, that's honorable, but when you're in it, I mean, you know, I'm just it's, I'm just happy that maybe we can at least improve somebody's gut health to improve their immune system. That's what I'm hoping for, maybe, because I'm seeing data from Argentina and Italy and different places that these molecules can do more.Definitely. That would be it would be, it would be awesome. We have a long way to go before we get to the end of the road on what's to be discovered in natural supplementation and how it can actually benefit us. Yeah, it's super cool. So this is awesome. This is our first abbreviated podcast, we went. We were aiming for 28 minutes, we went 32 minutes a little overboard. So it's, it seems like you and I can't do anything with that, but it's important. It's an hour's worth of material. Because I'm looking at the clock and I'm like, wow, we're an hour. So it is what it is. So just to recap Episode Five is all about coping and being happy. Learn from our Greek stoics. There's different techniques, you can listen to the episode on that. You can also sit there and reframe things, make it comedic, make it timeline, practice a little bit of negative negativism, so that you will miss the things and if you're anxious and panicked, you will not think right. And ultimately neuro linguistic programming will help you stay calm, a little different from what we normally talk about, but I think it's important.I think it's important to most of all, be safe, like and share. Come back and see us. Hug your family. Tell them that you love them. And we'll hopefully see you soon with some great info. Thank you so much for tuning in. Absolutely. Eric, thank you so much for everything that you do as a crna because you're you're intubating people and stuff you're right there. So thank you for what you do.Well thank you for what you do and making certain that we have have awesome opportunities to explore some science that may just benefit everyone. So I appreciate it.And I want to thank Angie Cook for everything she does for us.Heck yeah and and you know, while we're giving shout outs are going to be home. You were talking I know we're going a little bit longer here, but you were talking about stuttering.No, we're pretty much doing our normal time.Yeah, we're doing our normal stuff. Since since Ken brought up his stuttering if anybody was paying attention we lost a great icon. Right the very beginning of this pandemic and that was Bill Withers and he had a stuttering problem growing up also. And if you're just interested in just want to get caught up on his story, go to Amazon Prime I know has it you can probably find it somewhere else if you don't want to shop with Amazon. But look for his video version of still bill documentary. And that's named after one of his albums named still bill but. Incredible recap of this man who did not care about the fame as much as he just wanted to make great music he just wanted to write songs I mean he was...an awesome documentary. So still bill fought until the day that he died to help kiddos who suffered from stuttering and just really, really cool. So great pick me up anyway.All right, everybody, Episode Number COVID five a little more lighthearted. Thank you for everything that you do all our frontline workers, tune in next week. Share this with anybody who works in the hospital system because we're going to go around and work diligently to figure out how to protect everyone. Alright, y'all take care. Bye bye.

COVID-19 Files: Ep. 4.5

Younger with Dr. Robyn Benson

Play Episode Listen Later Apr 17, 2020 64:57

Hey, what's up everybody? Here we are on our COVID files 4.5. That means a point five we have our recurring super smart guests, my friend and colleague, Dr. Stuart Ackerman. Dr. Ackerman, would you please introduce yourself?Sure, Ken. Thanks for having me again. It's my name's Stuart Ackerman. I'm a gastroenterologist with digestive health associates of Texas. And we're glad that I'm here again to discuss more COVID type stuff.So on Dr. Ackerman and I did a COVID 3.5 Episode three and a half episode where we looked into the role of COVID in the digestive tract. Today, we're going to look at some journals and discuss the role of COVID-19 testing specifically the role of antibodies, and you're going to be hearing a lot about this. And so a lot of the shows that we're doing, we're a little ahead of the media. So that's what I'm really happy about is that every time we do a show, and then later the media kind of catches up, so. The one thing I do want to address and if you're watching this on YouTube, Dr. Ackerman, you've changed your look a little bit. I mean, you had this very beautiful luscious beard, you know Wolverine like and it's a little different is that because you're getting all the notoriety from the show or what's going on?Yeah, some sacrifices have to be made. So, as part of my practice, you know, although there's some restrictions because of COVID on doing procedures and seeing patients in person, I still I still have a significant number of emergency and urgent procedures that needs to be done and part of the protocol as recommended by all of our societies is that you've got to wear PPE these protective equipment and some of that is an N95 mask and an N95 mask when it goes over your your mouth and your nose, it doesn't fit to securely if you've got luscious locks like I did. So sacrifices needed to be made.So Dr. Ackerman did this really cool video where he's basically explained the whole process of this, and how certain sacrifices have to be made. So I suggest everybody go to his website. What is your website?It's www.stuartakermanmd.com Stuart Akerman dot comYou posted the video on your website, I hope.Yeah, it's posted on my blog on the website.That's awesome. I love the video. It's so cool. All right. So when you and I were discussing about doing this, and what I like is that you and I talk all the time. And we discuss journals and we do stuff and we kind of debate a little bit and we poke each other and you were you were discussing that, you know, hey, we should do a show on this. Do you want to do like a point counterpoint kind of thing where we should debate and I laughed because I immediately thought of airplane the movie from 1980 you're way too young for this but the airplane.I've done I've googled it.They were doing point CounterPoint. And you know, the whole point of the show is to be so obscenely on either end where the one guy so, a CRNA Jack Kerry that I'm not sure if you know him. Have you met jack? So jack would always laugh, he would use that quote whenever something would happen in the in our endoscopy center. If maybe the scopes weren't ready or a patient showed up late or something got off track, he would always say the same thing which I started thinking about about this. In the point counterpoint in airplane, the CounterPoint guy was like, they bought the ticket, they knew what they were getting into, I say, let him crash. This is not going to be quite like that. Because I think you and I will end up in the same spot ultimately when we're discussing this. So that's kind of where I thought where you and I were hoping to have a kind of a point CounterPoint. But I think we're gonna end up in the same spot. You kind of agree?Yeah, I agree. I think that it's, it's good to sort of flush out both sides of the argument so that you're more well rounded in your discussion. And I think that's kind of how we approach it, you know, that, we're we're looking at the same data. We're drawing our own conclusions, and sort of coming out on both sides of the argument. I think that's, that's good for any kind of evidence based discussion.Totally. And what we're going to talk about today is something that is super important, because it is how do we get the economy back on track? How do we use testing to do it? And we're going to take a look at the evidence based approach to this. And in fact, this is coming so fast that this morning I woke up, and I saw a couple different articles that that came out this morning. One of them was an article on a homeless shelter in Boston. And what they decided to do is do PCR testing on everyone in the homeless shelter, and what they found was that 36% of the people were positive at that moment, and we're gonna discuss what that moment means. So 33% were positive, but only 7.5% admitted to having a cough and only .7 even had a fever. The conclusion was in this article was holy cow, we need to do mass testing so that we can see who's really been infected. And then almost on cue, a New York Times article came out today, where it was a journalist that he opens with a with a classic Mark Moran. I'm a comedy fan Mark Moran line, where the the journalist says, "I know a guy. And because I know a guy and the connections I have, I was able to get my hands on a rapid antibody test. And I took the test, and I was negative. The problem is, I'm not sure it was a valid test." I'm like, this could not have been in a better time this guy did this. And that's what we're going to talk about today. You and I know guys.Yeah, we know people and this is the national and international discussion. Now if you've at all been watching the news, or reading papers or going on Reddit, you know that Italy, Spain, the United States to some degree, they're all discussing this idea of how do we figure out who has immunity? Is there a way for us to figure out who can safely come out of their homes, go back to work, and sort of jumpstart the economy again and jumpstart life? And it sounds dystopian. It sounds like it could be a great idea, it could be a terrible idea and anything in between. But what we don't have is we don't we don't necessarily know the details yet. And I think that's, that's what gets everyone confused, because there's no shortage of media outlets touting this as you know, the next great idea, but is it? I don't know. Well, we're gonna we're gonna get into that I there was an article written by I don't remember who wrote this, but it was just this just happened in the last couple days about ending the lockdown. And they interviewed a Harvard epidemiologist, and he said, well any of the lockdowns are going to be an effort with trial and error. There is no scientific evidence to this, he's like the best I can say this is we're all in a life raft. I'm not sure how we get to shore yet. What we're going to talk about is possibly how to get to shore. Because if you think about it, governments around the world, they need to triangulate the health of the people, the freedom of the population, and there's no scientific consensus. So what I wanted to do today with you, because you're a super smart guy, much smarter than me, let's kick some science. Let's go over some articles, and then play the pros and cons of each side of it. So I'll throw it back in your court. Where do you want to start with this?So I think, you know, we, we have a few articles that we definitely want to discuss as the basis for the arguments about immunity. I think before we jump into it, just to get a better sense for our viewers, we need to explain some of the terminology and the differences between the testing methods to understand what best to use to acutely diagnose someone with COVID-19 versus how do we tell that they're no longer infected, they're no longer sick and whether or not or at least to start that discussion of whether or not they have immunity.Absolutely. So let's start with what is the standard test being done when somebody shows up with a fever to an emergency room?So the standard testing when you're trying to figure out is this person currently infected and sick or...not sick, we know they're sick they're there is something called PCR testing. So in PCR testing, we actually will try to replicate the virus, right? The implication being that you gotta have virus in order to replicate it. So a negative test means there's nothing there to replicate. And therefore, you might have a fever, you might have some chills, you might have a cough, but you don't have COVID-19. On the flip side to that, if you start replicating virus, the virus has to be there. By definition, if a virus is there, you have viral infection. So PCR testing has been considered the gold standard for diagnosis of COVID-19 at this point.And let's talk about the what we did talk about on our last show the kind of pros and cons of that, because what we're learning. And what is fascinating is we're here today, what is the date? April, April 16, to April 16 2020. I mean, we may be eating crow tomorrow, because everybody, this is all changing. But what we're learning now is that a lot of people, I was listening, I don't remember who the virologist was, but he was describing the actual process. If you've had this swab done, it's not very comfortable, they get in there they try and get the cells that try and do this...it...there is some sampling error issues with this and possibly it's not in the back of the throat. We discussed how possibly could be in the stool. So there are some limitations to that particular PCR testing, and a lot of the studies we're going to refer to look at comparison to PCR.Correct. And so with this study is that in order to mitigate that risk for false negatives, they'll swab multiple areas and multiple sites to try to decrease that risk of missing a potentially positive person just because of sampling error.It's funny you say that because now after our last episode, and I'm pretty sure that they listened to our episode and this is why they did this because...I can only assume I can only assume that, that there's a Chinese doctor that saying that we should probably swab the anus and those that have recovered to determine if they have PCR positive. So before somebody is released from the hospital swab their anus,Yeah, right, I think fewer people are going to go to the hospital. We probably shouldn't publicize that.Um, you know, so the PCR testing now explain what the antibody testing is.So, when we talk about antibody response, and you might have heard a lot about this, you know, the buzz words are IGM and IGG. These are the two immunoglobulins that we talked about with infection. And once you have an infection in order to mount a response, that's really what we're talking about. And IGM is the immunoglobulin that comes up first. That's kind of the, the acute fighter for you to try to get the infection under control. And then once you're sort of getting to a point where you're starting to go towards recovery, you start creating idg and idg are more like your your memory, right? That's what that's what reminds your body and how to fight something. So when we talk about vaccinations, where we're actually providing immunity to people, what we really are doing is either providing directly IGG or giving what's called a live attenuated virus a small kind of stunted virus so that your body will see it react and create its own IGG. If I have encapsulate this in one sentence so that you remember the difference between IGM and IGG? I would say that IGM is what wins the battle for you. But IGG is what wins the war.I love that. I've never heard it. Did you...did you just, I mean, Is this yours?Yeah, that's a shower thought.I love that. You're exactly right. So, a lot of people if you've ever been checked for epstein barr virus, which is a very common thing. epstein barr virus will usually have an IGM and an IGG and people will realize that most of us are IGG positive, we've been exposed, which means you saw the virus and you carry these antibodies throughout your life. That is a I love the battle war thing that is awesome.I just think it's an easy way to remember it. And you know, similarly, you know, if you go to have a new patient visit at a primary care doctor and they say to you, well, have you been vaccinated for hep B? Have you been vaccinated for varicella, which is chickenpox. You're like, I don't know, I don't have that little card from when I was five years old. They're going to run some blood tests. And those blood tests are just checking for the varicella IGG and that and certain Hepatitis B IGG is because if you've got them, you're you're good. And if you don't you need either vaccination or boosters, right, because sometimes you might be immune, but that immunity can wane.We're seeing that with varicella. So we're seeing people actually, co host Eric Rieger developed shingles. Oh, wow. And it happens. It's happening to a lot of 40 year olds, a reoccurrence of varicalla, it's happening and so that we got into a long discussion about that when him and I were in Hawaii because he were in Hawaii, and he had a bad shingles outbreak which sort of limits going to the beach. Yeah.But it was all it was all kind of related to that. So yeah, that is a great explanation IGM wins the war. So basically, your your innate immunity The virus comes in your body reacts to it cytokines, they send white blood cells, they kill whatever, hopefully they kill whatever it is. And then they take it back to memory cells that say, look, next time this guy invades the house, make sure that we kill it before it causes any damage like it did this time. And that is initially they go, okay, we're going to send out some early troops, IGM, just in case it's out there, just look for this guy, they get a card, they have a picture, and they go out and then they mobilize the IGG which says you guys are our reserves that you will remember this picture, hopefully for the rest of your life. And if this invader comes back, you go out and handle it.Yeah. And you know, now that now that we understand that I think we can we can jump into some of these articles. And I think...yeah sorry.I was thinking...before we get into the deep aspects of these these other articles, I I was very impressed with when I threw out the Macaque study at you, and you're like, yeah, did you really read it? I'm like I read the abstract. This is a great example of what I did scientifically poorly, which was I read the abstract, and I've been quoting this article. And then you're like, yeah, read the whole article. So in the abstract, and not to sabotage where you were going, but I just want to do this that this is why we need to dive deep into the journals, because in the abstract, they described recently has been reported that discharged patients in China and elsewhere were testing positive after recovering. However, it remains unclear whether the convalescing patients have a risk of relapse or reinfection. So what they did is they gave COVID-19 to Macaque monkeys, they don't say how many they don't discuss anything. What they say is after the symptoms were alleviated, and the specific antibody tested positively, that positively the half of the infected monkeys were re-challenged half of the infected notably neither viral loads in nasal pharyngeal and anal swabs along timeline nor viral replication in all primary tissue at five days post infection was found in reexposed monkeys. And then you said to me yesterday, why don't you read the rest of the article?Right? Because if you I mean, we'll get into this in a little more detail in a couple minutes. But, you know, sort of a spoiler. This is the study. This is the study that's been quoted as the basis for immunity testing and talking about giving people immunity cards because it it's a it's a solid proof that immunity exists and you can't get reinfected. And if you read the abstract and you listen to all the pundits, you would think they they herded every monkey they had in China and created a cohort of thousands. In reality, when you read the study, they had four monkeys. They reinfected half.They reinfected two. So, not to say that the data is not valid, but you know, you have to have it with a grain of salt the size of the Rock of Gibraltar, you know? Yeah. So after I read it, I was like, oh, man, he wasn't kidding. And then they reinfected the two. And then they sacrificed them. And they call them adult Macaques. So then I went down a rabbit hole, typical Google rabbit hole. As it turns out, Macaques can live 20 to 30 years. The average age of these adults were three to five years. SoRight younger, you know, theoretically healthier,Theoretically healthier, much younger, preteens or teen style adults. And I get it that we don't want to sacrifice a whole bunch of macaque monkeys. I'd rather not sacrifice any animal or anything and have some sort of other way to test this. But this is just a great example of the media using this article me using the article and other you know, when Eric and I were talking on another episode I was bringing this up, I'm so thank you for pointing that out to me because that has to be you have to look at the articles and that's what we're going to do today is let's let's dive so I'm gonna throw it in you wherever you want to go with it, run with it, and I'll try and keep up.Alright, so before we hit that study, and we definitely want to talk about that because it's the it's the basis for the whole argument. There's there was a study or data set really published by the Chinese CDC, about the Wuhan experience, and I think it's good just to just to hear the numbers. So basically...Is it this one? Correct.Okay, great. Yeah. So this is the viewpoint characteristic of and important lessons from the Coronavirus 2019 outbreak in China is the title of the article.Yeah. and these and these numbers are current as of February which is at the end of the curve in Wuhan so they are completely valid numbers, you know, that they published. So they had 72,314 cases of COVID-19. And, you know, 62% of those were confirmed with some sort of testing. You know, a lot of those numbers came from people who just had the right clinical syndrome because, you know, much like us, they didn't have enough testing to go around, they weren't able to get all the testing at the same time. So, you know, some of those numbers are the people who were admitted and treated and may have been on ventilators but didn't have a confirmed diagnosis. But it seemed pretty likely that that that they were sick with COVID-19 and 3% of them were in advanced age of over 87. An 87%, though, fell into that 30 to 79 age range, with only 8% of the confirmed cases being younger than 30. So, you know most people fell into that fat part of the age distribution, with a very small percentage of them being on opposite ends of the young or old spectrum. Of the disease and this is where it gets really important. 81% of the cases were mild, right? So you might have had some sniffles, you might have not felt so great. But you didn't end up right, we get worried, right? We talk about ventilator shortages, we talk about, you know, overrunning the capacity of the hospitals. But the vast majority, four out of five, didn't really have much symptoms, if any. Severe cases-14% right, those are your hospitalized patients. And critical the ones that are new upper ventilators are 5%. So you know, if you break down the numbers, it's a very, it's not insignificant, but I think much like is the case in general we sensationalized the worst cases, and we got to be careful about falling into that trap.You know, just for that. I mean, right before we hopped on the call here, I had a friend call me because his father is very sick with COVID-19. So when we say that 80% of the people don't get sick If you're if you have a personal relationship, or it's you, that's 100% of the most important thing that's going on. And that's what's scary is the high infectivity rate of this. And in this in this article, the thing that stuck out to me was COVID-19 rapidly spread from a single city to the entire country in 30 days. And now we have a worldwide pandemic. So even though it's a small, the majority of people will have mild symptoms. But when you take into the account of the people that do get sick, that's how come we're taking it so seriously, but where you're going is how do we get that 80% back to work?Right. Right. And and also just having that knowledge that you know, we'd much prefer you don't get sick, but if you do, don't panic.Yeah. Yeah, everything is everything in the media right now is really bad. I've been talking to a lot of people. The New York Times article, the thing I didn't get into Was that the guy actually thought for sure he had COVID. Because a month before he had the classic symptoms, high fever, whole nine yards tested negative for the flu, and his antibody test was negative. So is it a valid test or not? And there's a lot of people that are like, you know what, I got sick in January, I got sick before we start talking about it here in the US. Has it been around? Has it been, basically, did it come to the US sooner? So who knows where this is all, we're all gonna sort this out.Right. And the case fatality rate in Wuhan was 2.3%. So 2.3% of the confirmed cases, you know, passed away, but 50% of those were critically ill patients. So it does sort of pass through that the sicker you are, the more serious it is.Yeah. And then that's coming out of China. And we have all this new data showing the people that do do worse, and we're starting to you know, partion everybody out. We know that the Italians have a much higher death rate. And then if you look at their demographic, they're older and all this other stuff. It's, we're learning. We're learning that in New Orleans here in the US, we're having a higher fatality rate higher, sicker rate, because of multiple different reasons. And you can start to predict where you're going to need more healthcare resources based on these based on these demographics,right. I mean, there were there were two specific issues that came up in New Orleans that may parallel the Italian subset in that it was a high density area with you know, Mardi Gras going on. And, you know, a lot of the case fatalities happened in a nursing home population, people had advanced disease living in close quarters, you know, so, this this may not be a new paradigm, it may actually be the same paradigm playing out in a specific way. Your audio is out. Sorry, what's your what's your take? What's your summary of this article then?So my summary of this article is that there's a really high number of people who got infected pretty quickly. This is a high infectivity virus. But of those, the vast majority of them did not get that sick, thankfully. But of the ones that did get sick, there are significant number who became critically ill and some who unfortunately even died. So it is serious. We do have to take it seriously and maintain social distancing and do all the things we can to flatten that curve. But if you do get sick, there there for most, you will you will see the other side okay.Yeah. So the other articles that you chose to talk about how does this play into this one?So the second article is answering the question of what is the true denominator? Right? How many people actually are infected, right? We're talking about these rates of infection. But the problem is in just about every spot in the world, we're choosing to because of limited resources, we're choosing to test people who are high risk- the patients who come in with significant symptoms, right? It's not just simply that you show up and say, hey, I've been coughing for a few days, I want to get checked for COVID. If you do that, you're gonna get turned around and told to go home and self quarantine, right? The ones who are sick, having trouble breathing, high fevers, those are the ones that are getting tested. So unfortunately, we're creating our own sample error. And this is this is playing out the world over so the natural follow up question is, what's the true denominator how many people actually are infected and they there's a study called the estimates of undetected rate among SARS CoV2 infected using testing data from Iceland. And they chose to look at Iceland in particular, because they have a sort of a dual phase program. They have the same exact setup as we all do, where they're testing nationally high risk individuals through their national university hospital system. But most of the population again, so they do throw in there, there still is a little bit of sampling bias, but most of the population is eligible for voluntary testing from a private company called deCODE genetics. So because they have a much larger sampling size, this became a good spot to try and figure out what that true denominator is. You know, like I said, there are some limitations because even though most people did fall into the ability to get or eligibility to get tested through this private company, they didn't get everybody. But they did get some nice demographic data. 44% of the people who went and got voluntarily tested had some mild sort of cold or flu symptoms. So these were not asymptomatic individuals by and far, many were, but not all. And based on their data, the results of both the national testing and the private testing 88.7 to 93.6% of infections are undetected infections. They're the ones that we don't know about.Say that one more time. Slowly.Yeah, so they created a range, they didn't have an exact number, but somewhere between 89 to 94% of all true infections. were being undetected to sort of flip that around the other way-we're only diagnosing about 6% of the true infections. So we're, we're leaving a lot on the table by design.Yeah. And so and I have to believe these guys. Now I know that your undergraduate degree was in economics, correct?Yeah, among others,Among others. Well, I got the biggest kick out of reading this article because looking at the math that they're doing, this is basically my insecurity nightmare. I'm like, I'm not walking around whenever I'm like really stressed, I don't have nightmares about being naked. I have nightmares about trying to take a calculus test or something. These stats are stunning. I mean, it almost looks like artwork, what they're doing, so I have to believe them that they're right. Because, it's pretty crazy.Yeah, it took me a little bit to read it and make sure that I understood what the numbers meant. And that and as we discussed it, the the first time around when we're talking about this article, I actually overstated what they were trying to say. Because I misunderstood some of the numbers. So after reading it two, three or four times, it made a little more sense to me. So...Well, I'm glad it made sense to you because it just I just looked at this and it just looks like I'm, I'm, I feel like I'm on goodwill hunting with that chalkboard and trying to solve the, whatever equation it is these things are they did a lot of math on this to extrapolate this to a nationwide thing, which means they had that they had the test. They showed how many people were being missed, and then they extrapolated it to their census.Right, and just to explain what I mean by numerator and denominator in this situation. So the numerator or the number above the line are the number of people who have COVID infection. The denominator is the population, right? So one point of bias in a study like this, that you have to understand whenever you're reading this, is you have volunteers by people who said I'm going to go get tested. You might have plenty of people who said, I'm fine. I'm not getting tested. I don't want to know.I'm not getting paid. So why should I drive over?Yeah, exactly. Maybe I'm gonna get exposed because I'm hanging out with all these people. So the true denominator, the population might be underrepresented. So even though we're saying that 6% of the people are the true and 94% are being undetected, might actually be a smaller number. But I think what you can take away from this is that we're only seeing the drop in the bucket. The question is, how much is that drop?So we have to figure out how much of the population has already been exposed. Because what it comes down to is what this study is telling us.Right.Yeah. So how do we get to the denominator here? What are some different ways to do it?So probably one way to do it, which hasn't been done yet, but is under discussion is random testing, right? Because if here you're saying the selection bias is in that only certain people are coming to you...well, maybe if you go to them, you'll be able to get a better sense of a smattering or a cross section of the population. And this has been one of the discussions now in the media, about in the United States, in particular about certain counties, getting access to testing, and setting up random testing protocols. And some of the discussion has been about mobile command centers, right, going out to people so that you decrease that selection bias.So if you're going to do something like that, it has to be a test that is easy has to be a test that is sensitive and more important to be...Gotta be cheap.Yeah.Gotta be cheap.It's gotta be cheap. You have to have a certain level of sensitivity and specificity. Can you explain to everybody what sensitivity and specificity is?Sure. So harking back to my medical school days, I remember this little, this little memory game that you play to try to remember the difference between sensitivity and specificity. And we call it spin and snout. So when you talk about sensitivity, sensitivity is the number or the percentage of ruling out the disease, whereas specificity is ruling in the disease right, so we want to talk about it. In other words, or another part of that is, if you have a positive test, do you actually have it? What are the chances that that that's a true positive, and you actually are infected? And on the flip side to that, if you have negative exam, how confident are you that you don't have it and we didn't miss the fact that you have it?Yeah. If you want an update on this, I went to Peter Attia MDs website and he does a whole thing on how to get people back up to speed with this epidemiology and in stats kind of terms, because it is confusing, but bottom line is, if you have a high sensitivity, high specificity, it's a good test.Right. Is what it comes down to.Yeah, any screening test you want to have, you want to know that it's picking up the right people and casting away the right people and not telling people incorrectly that they have something. And also not letting us lose the ones who truly have who we don't know.Yeah, so think about this: if we do a test, and it says that I am positive for the antibody, meaning that i have IGG, and it is a false positive, then I go around the world thinking I'm, I'm bulletproof, and I could be infecting people. And then I put myself at risk. If we take a test, and it is a false negative, then we're putting people in saying you don't have this yet, go back in your home, keep quarantine, you can't go back to work and all this other stuff. And that's kind of what we're going to get into right now.Right. The risk of it is it's the antithesis of social distancing.Yeah, yeah. So you pulled up another article, or this is the diagnostic value and dynamic variants of serum antibody, Coronavirus disease. What was your take on this article?So it's an interesting article for sure, but I would caution that when you read it, kind of similar to the monkey article, which we'll discuss next, the numbers are small. And you always have to be careful whenever you're trying to interpret data in a small data set, because the smaller it is, the higher the risk of bias, the unintentional but but bias in the numbers. So it was the first published data that compared the PCR testing, versus well, rather, they took a bunch of patients who were all being tested for COVID with PCR, and the ones who tested negative and therefore were known to not have COVID right? We might walk around thinking we don't have COVID. But we don't know whether we do or don't since people can be asymptomatic for so long. These are patients who we know don't have COVID and use them as the control group compared to the PCR positive patients who are known to have COVID. And what they did is they then looked at those patients, and tested IGM and IGG to know who makes it how much and whether or not that can happen in the control group as well, to say it another way: if I'm infected with COVID, and I make IGM and IGG, but somehow someone in the non COVID group does it as well, how valid is that to know that I'm immune?Yeah.Right? The idea is that only the people who have been exposed and therefore can protect themselves should generate that immunity or should we should be using that as a marker for the immunity so a couple interesting things are that some people that's an important point did not make IGG. And on the on the control side, three people did make IGG. However, a big caveat in that is that they made it a much lower titer. So they had a they made some IGG but less IGG than those people who were exposed to or had active viral replication. So another point I'll make is that this is a it's a very interesting article, and it's been discussed a lot. It's a journal pre proof article. So it does mean that it hasn't been published yet. But the journal has accepted it for publication. It's already been through peer review. So this is still a very legitimate publication. So there were in the two in the two sides, there were 43 patients with PCR positive confirmed COVID-19 and compared to their control group of 33 patients who were these rule out patients, patients who came in they, they thought they were sick and potentially had COVID, but the PCRs were never positive. And another good point I would make is, these patients have multiple testing points. They were tested at multiple times. So to decrease...Multiple times in the same location, though right? Nasopharyngeal swabbing.Right. So so they're trying to control for that. Well, what if there, we missed it the first time, right? So then they're going to repeat it again a few days, which gives you a trend over over time. So but but I agree, the point being that it was all nasopharyngeal swabs, I think oral too nasal and oral, yeah. So limited to one type. So you can still you still have that bias of did you not do it adequately? You would hope it's only and they don't mention this, whether it was or not, that's it only a certain few people who are doing the testing, so that you're controlling for variables of maybe some who do it better than others. And maybe get better sampling. So they don't mention that but because it was all done in one site, you have to assume for the moment that there's only a few people who are doing the testing, so they know what they're doing. The sensitivity, I'm sorry.Oh, I was just gonna say what I found interesting in this is this suspected infected patients were discharged from the hospital once the results of two time molecular tests in 24 hours were negative. So basically, in my interpretation of this understanding, now, the limitations of the testing, they may have sent people out that were not PCR positive, that could later develop IGG and IGM. So when you get into the sensitivity and specificity of this, it is this is this is as good as we can get. But it may change as we gather more data.Right. Right. So the sensitivity specificity for IGM and IGG to diagnose an infection was 48% and 88.9% of sensitivity. So IGM was 48 and IGG was 88.9 and 100% and 90.9% specificity, right? So, in other words, if you had IGM, that meant that you had the infection because it's an acute marker that would only happen if you've been acutely infected. But if you didn't have IGM, it did not mean that you weren't infected. Right? So just to sort of wrap your head around that it's really really good as a marker if you have it, but if you don't have it doesn't give you a whole lot of confidence.I love how we're doing this because the media just glosses over it and just confuses people. My patients are calling me all day long asking all these questions.Yeah, it's important to understand what it is right and the media doesn't kind of give you a primer to explain the background of what they're talking about. They just give you a two minute soundbite and you're sort of left on your own to interpret it. Exactly. Sorry to interrupt go on. No no problem at all. So they found that as you would expect, given that IGM comes first and then IGG follows IGM titers would rise and then they'd fall because as you get over the acute infection, you no longer need your IGM. But the IGG titer would rise until they were 100% in those people that produced IGG, right, so the ones that were making IGG made them. It was always higher, for whatever reason, and this, this is not clearly explained, but the titers of IGG were always higher than the titers of IGM. I think it's just something to sort of keep in the back in your mind just because we don't yet know what titers means. So it's just getting all the data you can and trying to figure out what it means going forward is important. The IGG positivity rate was over 90 was up to 90%. And it didn't really change it once...from the time that you were virus positive with PCR to your post infectious viral negative state. But the titer of IGG was almost double once you pass the infection, which that starts giving you that glimmer of hope about immunity, right. Because as you're fighting the infection, it's not as important to remember, you need someone who's actively on the front line. And that's where your IGG IGM helps you. But once you're done, you want to you want to remember that you want to be stone cold, you want to know that if you get any kind of exposure again, your body is ready to jump into action.I mean, this is just getting back to your analogy, what you have are some special, we've got special ops that have a picture of something and they say when this thing shows up, kill it before it does anything. And all they do is wait. That's what the IGG is doing is waiting for the possibility of seeing that and they just get after it.Right. So just to sort of talked about the the the sort of underside of this, three of the 33 patients in the control group are IGG positive, right. So that that makes you step back just a little bit in saying that, well, if you got the IGG, you're good, right? But the important thing is that the titers were lower. So they talk about the the units, the units of positivity for this assay, were 1010 units per milliliter, and those that were in the control group had no one higher than 15. So they were sort of a low kind of weak positive compared to those in the active group, who all had much higher at least twice the normal titers. So that might be an important piece of information, right that not only figuring out who is IGG but how much maybe there's a threshold value that confers immunity. 27 of the known COVID patients has IGG testing during the infection, three of them didn't make any IGM or IGG, so whoever didn't make IGG also didn't make IGM. It's interesting because the way I look at this is probably different than almost everybody who reads this article. I'm sure everyone who looks at it and it's valid is gonna say certain people don't make it. What I look at it is that's kind of an amazing thought. 10% of the people didn't make IGM or IGG and still fought off the virus somehow. So there's some sort of mechanism of secondary mechanism to be able to successfully defeat the virus beyond this, the typical virology that we know about.Well, I okay, so point CounterPoint. What if they're catching this person at a point in time where the IGM is dipped down and the IGG is coming up? So you're going to have two overlapping...Right you're in a window right?You're in a window. So did they check them at the wrong time?Right. That's a great thought. The catch is they did this at least three times separated over several days, going all the way out to 28 days post infection. So I suppose it's possible, but given what we know about the curves of IGM and IGG, even if you think maybe you were shifted over in time, you should have caught it somewhere. And maybe you don't get one maybe maybe you only get one, maybe you don't get both. We should have seen something.So what you're describing is that people that had an innate immunity, but they did not develop the adaptive immunity. In other words, their body's initial response may have been effective enough, but they did not develop. So those people, the question is, can they be reinfected? Will they have a possibility of the virus, having a resurgence and come back and hit them again? Interesting.Yeah. So that's the discussion. The discussion is do these people have immunity now, right? If you're making the supposition that you need IGG to have immunity, and these people can't make IGG, are they subject to reinfection? I would argue it goes even deeper. We're trying to get serum right draw blood from people who have had infection, to look at IGG titers to understand how much is needed for immunity. How much is enough? I would want to know about the serum of these people. What makes it different? Is there something is there a different way that we could be looking at this to confer immunity? Is there something else that maybe can work in concert?Hmm. So here you have the subset of people which is a significant amount and it's small study 10%. Right. So a subset of people that survived did not produce the antibodies, and going forward and some sort of weird society where we have to have immunity passports to go around. Peter Attia was talking about when you get bracelets for people to show I'm this I'm that which is gets a little bit big brother-ish and it gets real scary thinking about that. But there could be a subset of people that will not produce antibodies, but their innate immunity prevents them from getting infected. And we can't withhold them from going to work. We can't stop them. That's a fascinating observation. I did not see it that way. I was I was of everybody else that read this article and just went 10% didn't produce it. So...Yeah, but it's going back to what you said. I mean, this is this is why you gotta analyze articles and you got to have multiple people looking at it because people can read articles and have the same data and draw completely different conclusions.Much like everything else.Much like life. Let's, let's jump into the sort of article the day before we start talking about the pros and cons of these immunity badges or licenses. The we want to talk about the the Macaque monkey study. And...What's the only reason why I threw that out first not to describe it, but it just shows why you have to pay attention and read the articles yourself and have two different people interpreting it differently. Right. So it's a very small study. It is pre-publication, and it has not been peer reviewed. So it is being touted as kind of the be all and end all for the discussion about immunity. But it is a very much in the pubescent stages of research.It's fascinating because I heard Dr. Fousey on a CNN news thing. We believe that because of the macaque monkey study, and then I heard Dr. Hotez go on Joe Rogan. He said we're we're sure that we can develop immunity because there was a macaque monkey study and everybody just keeps saying the macaque monkey study the macaque monkey study. I don't think there's another one out there. I tried to look I didn't find one. This is the one that I found.Yeah, no, I did the same. And, you know, like I said, it's it's fascinating but has to be taken with a big grain of salt. So let's, let's jump into it. Yeah. The whole reason why they did this study, it was prompted by reports of patients who have been discharged and considered cleared from virus and then they were coming back with reinfection or raising that question of is this a relapse or reinfection? You know the difference being relapse, that you have the same infection you did and you just got sick again, versus reinfection that you actually got sick a second time. And it implies that there's no immunity.Big difference. So they followed four rhesus monkeys. And they infected all four of them. They actually gave them inoculations of the SARS CoV2 virus and they developed a lot of those typical symptoms that we're seeing in people around the world. Once they the symptoms were alleviated, and the viral replication as judged by, as you said, respiratory and animal swabs and PCR had all subsided, all appropriate antibodies, so IGM and IGG and there's actually a whole bunch of other ones we didn't even touch on. They were all there, right? So they sort of validated the subset of the four monkeys by saying these all created everything appropriately and therefore, we can look at them for some information. They euthanized one of the monkeys from the start. And they basically took various organs and tested the organ tissue to see if they would be PCR positive and they found evidence of viral replication all over the body: nose, pharynx lung, gut, spinal cord, heart, skeletal muscle and bladder all displayed PCR positive COVID at the time of infection. Two of the Monkey so now you're down to three monkeys. Two of the monkeys were then re challenged, where they inoculated them a second time with SARS CoV2. So again, this is talking about reinfection, not reactivation. All the monkeys. So all three monkeys were then tested for viral load. And none of them were found to be PCR positive. So the one monkey who was left as a control and the two monkeys who were re inoculated, none of them had PCR positive disease at this point. They then took one of those reinfected monkeys euthanized that monkey as well did the same kind of testing, looking at all those different organs and trying to see if they were PCR positive and found that they were negative in the tissueIn all of the tissue and that's pretty shocking how disseminated that virus was in the first one. So that's impressive.Yeah. So very interesting data very interesting information throws out a lot of very positive possibilities here now for infection and the ability to fight off reoccurrence. But, gotta gotta to be very skeptical, right? I mean, for monkeys, you know, they all displayed antibodies. And from the last study we looked at, we know that that's not true, right? If you have those 43 patients, you know, sort of looking at that and say, if I only took four of them, and looked at those four people, and they all made antibodies, I draw conclusions from the study. Well, I guess everyone makes antibodies, but we know that's not true.Yeah, that is a that's a very interesting analysis on a study that's being thrown around in the media like crazy. Nobody's talking about that. And if you read their abstract, I'll say it one more time, like I did. It seems like they had 1000 monkeys. So great job on interpreting that and getting into the details and you know, having the time during Passover and stuff to go into detail like that, because...Yeah, I mean I just got a cup of coffee, got some matza just sat down and went through all these studies.Well, you're better than me because it's it's like drinking out of a firehose, I try to sort through which ones I'm going to take a deep dive in. And I like doing this with you. I like doing these point five episodes where we do do deep dives. And, and you challenged me to look at some of these studies. So I had a long interview yesterday with Matt Atwood, who's the CEO of a company that has access to rapid point of care IGG, IGM testing, where they actually have the ability to take a finger prick like a glucose stick, and then you can see if you're IGM positive, IGG positive. And it's interesting because you had also sent me that study and he sent it to me about the Laredo was it El Paso or Laredo?Laredo yeah...Laredo. Yeah. Why don't you go ahead and tell everybody about what kind of a fiasco that was?Well, the short version is best intentions for sure. The city of Laredo ordered, I think half a million testing kits to try and stimulate their economy, right? They wanted to...Just to clarify, it was half a million dollars for 20,000 kits. So they spent half a million dollars.Oh, thank you. And they basically wanted to go out and test everyone and see if they could figure out who's IGG positive and say that those people can go back to work and sort of get Main Street running again. And it turned out that the kits were not quite up to snuff. And unfortunately, it was a bit of a loss for the city of Laredo.So people are asking like, well, how is this happening? And I just want to just clarify this a little bit. It's what happened in China is exactly what President Trump is doing here. When they realized that they were behind the curve on this, and they needed masks and gloves and testing kits, China went to facilities like toy manufacturers, and they went to different manufacturing companies and said, you're going to stop production on that. Here's your parts to make masks, here's your parts to make test kits. And here's how you're going to do it, figure it out. So these were not already pre designed medical locations. They were doing what the government told them to do. And then they made a bunch of these things. They shipped them out, the US bought a bunch. And then we realized...a lot of these things are not effective, and they shipped them back, discussed possibly suing this and so then China had to step it up and be like, well, we can't just force you to do this. Well, as it turns out, there's a bunch of that stuff still floating around in the US. And there are some companies that are saying, well, I'll just repackage it and sell it. And that's kind of what happened to these guys. So for instance, our group, I got an email from somebody in our group that said, we have access to these IGG kits. And I looked into it and as it turns out, I, we contacted the manufacturered for company and they're like, yeah, we got a bunch of those kits that are not valid because they're not certified. So a company out of Houston bought us. And then they contacted our group and offered to sell it for dirt cheap. And it's, you get what you pay for, I guess.Yeah, I mean, it definitely was a great deal. They were super cheap, but...couldn't really do much with them unfortunately.And then from as doctors, imagine, if we tested people with an unreliable test, and we said look, the we all you and I carry liability all the time, but at least we can say this test was FDA shown to be this the sensitivity specificity, so there is a 95% chance that the information I'm going to give you as correct, you're going to assume and I'm going to assume that there's a slight possibility that it could be wrong. If you're positive, then what we're going to do is send you for another more distinct test, which costs a lot more money, it's going to be serum and that's kind of where I think this needs to go. You do mass screening, like we did with well, quite honestly, HIV, I remember we did the rapid HIV and then you do the the Elisa test or whatever it was afterwards to try and really determine what's going on. So we have these people that if we can screen them and get the IGG IGM and then do a secondary test and prove that they're that they have antibody. Then now the next discussion is alright, Dr. Akerman. We've got IGG people running around with their badge saying I can work I can do things. What are the limitations of that?Well, I think there's there's some issues that are...and I want to be clear, I, I agree that we need to figure something out. And this opens up a world of possibilities. But we're in the infancy because there's a lot of questions that haven't been answered. So first of all, do we know are there specific titers that confer immunity? Because if there are, a simple little blood test that just says yay or nay might not be enough, right, we have to make sure that all the manufacturers are assessing at the same level to call that positive. Right? If we know that you need titers of 20, let's say, and you have a test that calls it positive at 10. Right? You're creating a ton of false positive results. So you got to be really, really careful about that. And, you know, again, we haven't answered that question just yet. Is there the possibility of reinfection? So what does immunity mean? Right, we have all this data now coming out of South Korea because they've had over 100 people come back who were discharged from hospitals being told that they've cleared infections and that they're no longer sick. And they've actually come back and have retested positive by PCR. But what does that mean? Does that mean that they've gotten the infection again? Does that mean that maybe they were kicked out too quickly? Maybe that their viral loads had dropped? Or they simply had sampling error. Right. When they got tested the day before, maybe they just didn't pick it up in the right spot.Exactly. So the other articles that you talked about bringing that up, but it is fascinating, because this is just case reports coming out of South Korea. And everybody that looks at this nobody wants to believe that you can get reinfected like like that is like the the that is a doomsday prediction. So we're going to say, look, the macaque monkey study which you've kind of already said take it with a grain of salt, the size of Gibraltar and then this the IGG so it's the good news is looking at SARS CoV from 2003...they those people have been looked at years later a decade later, and they've maintained their immunity. Now, I challenge that there are some possibilities that these tests, although they're COVID-19 specific, what if some of these people test positive because they have IGG to SARS CoC? That was right. That was an argument that a PhD brought to me. Because he did...I was on the I was on a zoom call yesterday with a virologist who did the original research on that and he's like, doing this he's like, well, we're seeing that some people can develop antibodies which made a mistake that being said, I don't know that these fingerpricks there was a article that just came out today, that detection of SARS CoV2. They found the binding protein to be specific so the test you can still do a test specific for SARS CoV2. And I'm not sure if these IGG IGM are can actually do determine that. So more studies are gonna have to be kind of vetted for this.Yeah. And I think that, you know, it begs the larger question, what do you do with those false positive results, especially if you don't know that they're falsely positive? Right? Again, like you mentioned earlier, patient could be walking around thinking that they're bulletproof. And it turns out, not only are they not bulletproof, they might now get the infection and pass it along to everyone. It becomes part of the larger discussion about herd immunity, right? Because if we're getting all these people that now are immune, and we're putting those people out in the population, then the people that they're coming across are not as at risk. Right, but we don't know what that critical number is to create that herd immunity.Yeah, absolutely. There's a lot to discuss and clearly you and I can get together and try and vet some of this stuff as the literature comes out. I appreciate you taking the time to do that. Unfortunately, it's starting my telemedicine time right now. But where can people find you Dr. Akerman?The easiest way is to check out my website. There's a lot of information about my practice there and I've been trying to update my blog with useful information. And that's at www.stuartakermanmd.com.Yeah, so clearly this is a super smart guy watch his videos he actually has a pretty good sense of humor and has some pretty interesting stuff and his the videos you're sending me your kids which we will not discuss today was pretty pretty funny also so quarantine in the Akerman house should be a some sort of big brother type thing where it's just funny it's hilariousYeah, we're thinking of pitching it to the networks in the near future.Alright buddy, I appreciate you taking the time so go to stuartakermanmd.com You can reach me at on Instagram at kbmdhealth and kbmdhealth.com for the website. We are currently oh good news, we now have brought a leak on our website. So BrocElite, Atrantil, and CBD. We're having some pretty good results with that we can get into that later but today was much more of an academic discussion. Thank you so much, Dr. Akerman for joining now I got to get to the real job.Thanks Ken. Have a great day.Alright buddy. Have a great day.

Microbiome Myths and Misconceptions

Nourish Balance Thrive

Play Episode Listen Later Apr 10, 2020 66:55

Microbiome researcher and scholar of integrative gut health Lucy Mailing, PhD. is back on the podcast with me today. Lucy just completed her doctoral degree at the University of Illinois at Urbana-Champaign, where she studied the effects of diet and exercise on the gut microbiome in states of health and disease. She has authored numerous peer-reviewed journal articles and recently won the Young Scientist Award at the International Scientific Conference on Probiotics, Prebiotics, Gut Microbiota, and Health in 2019. On this podcast, Lucy discusses her recent talk at the 2020 IHH-UCSF Symposium on Nutrition and Functional Medicine. The topic is myths and misconceptions about the microbiome - and some of these are quite surprising! We discuss gut testing methods and why some are better than others. Lucy explains why you consider skipping probiotics after a course of antibiotics and shares what to do instead to support repopulation of a healthy microbiota. She also discusses some of the best and worst gut-health supplements. Here’s the outline of this interview with Lucy Mailing: [00:00:30] Why care about the gut microbiome? [00:01:37] Previous podcast with Lucy: How to Optimise Your Gut Microbiome. [00:03:52] Unschooling and self-directed learning. [00:04:40] Book: The Carpenter and the Gardener by Alison Gopnik. [00:05:45] Podcast on unschooling: How to Support Childhood Cognitive Development, with Josh Turknett, MD. [00:06:16] Lucy speaking at UCSF: Microbiome Myths & Misconceptions (on Facebook). Slides from her talk. [00:07:46] Lucy's talk at the Ancestral Health Symposium 2019: Modulating the gut microbiome for health: Evidence-based testing & therapeutic strategies. [00:09:06] Myth: Culture-based stool testing is accurate. [00:11:00] Companies currently using 16S: Thryve and BiomeFx. [00:11:28] Podcast: How to Use Probiotics to Improve Your Health, with Jason Hawrelak. [00:12:16] Diagnostic Solutions GI-MAP. [00:14:34] Metagenomics; Onegevity. [00:14:56] Doctors Data and Genova have now added PCR (polymerase chain reaction) to their tests. [00:15:33] Parasites Blastocystis and Dientamoeba fragilis. [00:17:35] Jason Hawrelak’s course: Blastocystis & Dientamoeba: Gastrointestinal Pathogens or Commensal Symbionts? [00:17:39] Blastocystis.net. Book: Thoughts on Blastocystis, by Christen Rune Stensvold. [00:18:45] Gut dysbiosis is driven by oxygen leaking into the gut; Study: Rivera-Chávez, Fabian, Christopher A. Lopez, and Andreas J. Bäumler. "Oxygen as a driver of gut dysbiosis." Free Radical Biology and Medicine 105 (2017): 93-101. [00:19:04] Blastocystis might buffer oxygen influx, preventing the overgrowth of other pathogens. Study: Tsaousis, Anastasios D., et al. "The human gut colonizer Blastocystis respires using Complex II and alternative oxidase to buffer transient oxygen fluctuations in the gut." Frontiers in cellular and infection microbiology 8 (2018): 371. [00:19:40] Blastocystis colonization correlates with a higher bacterial diversity; Study: Audebert, Christophe, et al. "Colonization with the enteric protozoa Blastocystis is associated with increased diversity of human gut bacterial microbiota." Scientific reports 6 (2016): 25255; And the opposite result: Nourrisson, Céline, et al. "Blastocystis is associated with decrease of fecal microbiota protective bacteria: comparative analysis between patients with irritable bowel syndrome and control subjects." PloS one 9.11 (2014). [00:20:02] Myth: We know what a “healthy” gut microbiome looks like. [00:20:06] Lucy's blog on the elusive “healthy microbiome”: A new framework for microbiome research. [00:22:43] Microbial signatures of dysbiosis. [00:26:06] Myth: Everyone needs comprehensive gut testing. [00:27:37] Ivor Cummins and Malcom Kendrick podcasts: Should You get a CAC Heart Scan or Not? Part 1 and Part 2. [00:28:14] Myth: Breath testing is a reliable way to test for SIBO. [00:28:27] Lucy's blog posts on testing for SIBO: What the latest research reveals about SIBO and All about SIBO: Small Intestinal Bacterial Overgrowth. [00:29:40] Culture-based testing methods underestimate the number of bacteria in the small intestine by about a hundredfold; Study: Sundin, O. H., et al. "Does a glucose‐based hydrogen and methane breath test detect bacterial overgrowth in the jejunum?." Neurogastroenterology & Motility 30.11 (2018): e13350. [00:30:53] Orocecal transit time ranges from ten to 220 minutes; Study: Connolly, Lynn, and Lin Chang. "Combined orocecal scintigraphy and lactulose hydrogen breath testing demonstrate that breath testing detects orocecal transit, not small intestinal bacterial overgrowth in patients with irritable bowel syndrome." Gastroenterology 141.3 (2011): 1118-1121. [00:32:43] SIBO might not produce enough hydrogen to result in a positive breath test. Sundin, O. H., et al. "Does a glucose‐based hydrogen and methane breath test detect bacterial overgrowth in the jejunum?" Neurogastroenterology & Motility 30.11 (2018): e13350. [00:34:36] Myth: Most bloating, distension, gas is from SIBO (and we neeed to kill the overgrowth). [00:34:45] Small intestinal dysbiosis, not bacterial overgrowth is what underlies a lot of gut symptoms; Study: Saffouri, George B., et al. "Small intestinal microbial dysbiosis underlies symptoms associated with functional gastrointestinal disorders." Nature communications 10.1 (2019): 1-11. [00:36:09] Mark Pimentel's research group. [00:37:04] How to support the gut ecosystem; serum bovine immunoglobulins (SBI). [00:38:25] Orthomolecular SBI Protect. [00:38:38] Myth: A high-fat diet is bad for the gut. [00:38:52] Misconceptions from the scientific literature on high-fat diets. [00:39:54] Diet alters the gut microbiome composition within 48 hours; Study: David, Lawrence A., et al. "Diet rapidly and reproducibly alters the human gut microbiome." Nature 505.7484 (2014): 559-563. [00:41:06] The Hadza hunter-gatherer microbiota cycles with the seasons; Study: Smits, Samuel A., et al. "Seasonal cycling in the gut microbiome of the Hadza hunter-gatherers of Tanzania." Science 357.6353 (2017): 802-806. [00:42:41] Ketones may support gut barrier function. Study: Peng, Luying, et al. "Butyrate enhances the intestinal barrier by facilitating tight junction assembly via activation of AMP-activated protein kinase in Caco-2 cell monolayers." The Journal of nutrition 139.9 (2009): 1619-1625. [00:44:45] Myth: More exercise is always better. [00:46:05] Zinc carnosine may reduce exercise-induced gut permeability; Study: Davison, Glen, et al. "Zinc carnosine works with bovine colostrum in truncating heavy exercise–induced increase in gut permeability in healthy volunteers." The American journal of clinical nutrition 104.2 (2016): 526-536. [00:46:45] Myth: You should always take probiotics after antibiotics. [00:47:51] Probiotics can delay the restoration of the native microbiota after antibiotics; Study: Suez, Jotham, et al. "Post-antibiotic gut mucosal microbiome reconstitution is impaired by probiotics and improved by autologous FMT." Cell 174.6 (2018): 1406-1423. [00:49:20] A better strategy: supporting the gut epithelial cell with butyrate; Study: Rivera-Chávez, Fabian, et al. "Depletion of butyrate-producing Clostridia from the gut microbiota drives an aerobic luminal expansion of Salmonella." Cell host & microbe 19.4 (2016): 443-454. [00:51:37] Myth: Prebiotics work the same for everyone and always feed good bacteria. [00:52:45] Blog post: Resistant Starch: Is it Actually Good for Gut Health? [00:53:12] Cooking food affects microbiome; Study: Carmody, Rachel N., et al. "Cooking shapes the structure and function of the gut microbiome." Nature Microbiology 4.12 (2019): 2052-2063. [00:54:27] Variable glycemic responses to Fructooligosaccharide (FOS) and Galactooligosaccharide (GOS); Study: Liu, Feitong, et al. "Fructooligosaccharide (FOS) and galactooligosaccharide (GOS) increase Bifidobacterium but reduce butyrate producing bacteria with adverse glycemic metabolism in healthy young population." Scientific reports 7.1 (2017): 1-12. [00:55:32] Myth: All herbal antimicrobials are safe and effective. [00:56:13] Grapefruit seed extract inhibits a broad spectrum of bacteria and is toxic; Study: Heggers, John P., et al. "The effectiveness of processed grapefruit-seed extract as an antibacterial agent: II. Mechanism of action and in vitro toxicity." The Journal of Alternative & Complementary Medicine 8.3 (2002): 333-340. Presentation by Jason Hawrelak, PhD: Phytotherapy in the Treatment of Dysbiosis of the Small and Large Bowel. [00:57:03] Herbs that have been found to be useful: Atrantil, Iberogast, triphala. [01:00:44] Current projects: blogging, consultation, creating training courses. [01:03:02] Lucy’s website, support Lucy’s work on Patreon.

american university health culture science phd nature medicine blog current illinois nutrition journal md myth myths diet companies treatments cooking misconceptions presentation previous gut lopez scientific tanzania gut health seasonal oxygen herbs functional medicine microbiome pcr christophe frontiers gardener probiotics slides variable zinc mechanism sibo urbana champaign colonization genova grapefruit improve your health actually good gastroenterology salmonella unschooling prebiotics ketones microbial jotham john p depletion sbi gos plos dysbiosis fmt caco hadza sundin gut microbiota modulating alison gopnik ivor cummins bifidobacterium butyrate george b andreas j metagenomics ancestral health symposium christopher a atrantil josh turknett onegevity blastocystis lucy how dientamoeba

Your Health, Your Gut, Your Microbiome, They’re All Connected! — Dr. Ken Brown

Play Episode Listen Later Apr 6, 2020 29:17

Key Takeaways: Dr. Ken is trying to bridge the gap between traditional medicine and natural solutions. Why are we seeing so many gastrointestinal issues? Leaky gut can lead to inflammation, which can lead to autoimmune disease and cancer. The overall health of the American public is declining. The good news is that with the abundance of information out there, a lot of Dr. Ken’s patients are self-taught. There are three things that cause leaky gut 1. Infection or bacterial overgrowth. 2. A molecule called zonulin. 3. Diet. The problem is that nobody is Dr. Ken’s field believes in candida. We’re not going to be better than Mother Nature. Finding a natural solution helps keep the rest of your gut health in balance. Dr. Ken has developed a product called Atrantil to help the gut microbiome. People are not getting enough polyphenols, which can often be found in a Mediterranean diet. Why is having a healthy gut important? Episode Summary: Dr. Ken believes we can use natural solutions to help heal the gut. He doesn’t believe in ‘bad’ bacteria, only that they’re just growing or living in the wrong place and we can leverage the power of Mother Nature to help heal ourselves. When our gut is out of alignment, we can develop symptoms like brain fog, fatigue, and even depression. Dr. Ken shares in today’s episode how you can bring your gut health back to normal and what are the causes of a leaky or inflamed gut. Guest Bio: Dr. Ken Brown received his medical degree from the University of Nebraska Medical School and completed his fellowship in Gastroenterology in San Antonio, Texas. He is a board-certified gastroenterologist and has been in practice for over 15 years with a clinical focus on inflammatory bowel disease and irritable bowel syndrome. Dr. Brown has declared that his mission is to bridge the gap between medical & natural science. Resources for a Younger Lifestyle: Dr. Robyn Benson’s Free Youthful Aging eGuide Dryoun.com — Download Dr. Youn’s free eBook, Ten Things Every Plastic Surgery Patient Must Know. Kennethbrownmd.com Atrantil.com Lovemytummy.com/benson — Use code "Benson" at checkout for 15% off of your purchase of Atrantil. Evanbrand.com Quotes: “All health begins and ends in the gut.” “It’s often said in biology, the more complex something is, the more important it is.” “You have to continue to support the bacteria that are there and get rid of the bacteria that are living in the wrong place.” “Now we realize the gut actually has a direct conduit to cause neuroinflammation, brain inflammation, that can lead to anxiety, depression, autism, CTE.”

COVID-19 Files: Ep. 2

Play Episode Listen Later Mar 29, 2020 70:25

Okay, welcome KBMD health fans and gut check project fans, it's time for COVID installment number two. These are the code files where essentially, myself and Dr. Brown, a co host we're going to address the latest in research for coronavirus as it applies to healthcare and our community. Dr. Brown, how are you doing?You know I'm doing is I'm doing well considering the state of how a lot of people are probably struggling through this process. Once again, the COVID files I think you and I really enjoy joking around and stuff, but this is not something that I want to joke around with today. So the show right now we're becoming much more sciency than we've ever been. And it is because I want to make sure that anything we discuss has a reference to it. So let's begin by saying that this is a show and not intended to treat diagnose anyone. I'm a medical doctor. With the current state of anxiety I'm trying to sift through hundreds of articles being published daily because this is a global problem. And I am fortunate enough to have our secret weapon which this week I was on Dr. Chang Raun's in Darrel Hill summit with Dr. Hyman and some other incredible people, Dr. Pompa, Dr. O'Brien and all these people and I, I told them all that Angie Cook is our secret weapon. And then on the CBOE SOS summit yesterday with Chevonne Sarna, I let it drop again. So Angie, thank you so much for working hard and diligently with me to try and get through all of this literature. Cats out of the bag. She is a certified nutritionist and Rn one of the smartest people I've ever met, and she sent me this email right before we went on. Today the numbers are staggering and the stories of what our healthcare workers are facing is heartbreaking. Please be careful. So what we're going to talk about today is mind blowing, to be honest. And I'm just going to be honest. In the sense this is no, this is not opinion. This is not based off of anxiety, or based...this is strictly the science. And this is not the time that I want to, I want to be perceived as I mean, because one of the concerns Eric, you and I've talked about this, I want to shout everything that I've learned from the rooftops, but I don't want to come off as somebody that's saying that I want to try and make money off of this particular crisis. That's not at all what I'm trying to do here. What I'm trying to do is show you the science. So that being said, I've got so much new information. Last time on our COVID one files, we're going to say how we're going to talk about what you can do with lifestyle and supplements. We're still gonna do that. Absolutely. And I actually learned a lot from being on Chang Raun's summit. You can look that up. It's Raun, Chang Raun. Some of his experts are functional medicine experts that understand the supplements better than I do. And I took notes while I was there. And I was a panelist on that. And the stuff that I talked about was really well received by his panelists as well. So everything is a moving target right now. So this is going to be I'm calling it a mic dropping show. Because if I don't get too geeky, and that's your job, Eric makes sure that I don't go into the weeds and be a nerd because I am a nerd to the nth degree. Angie and I have been nerding out crazy, like hair, you know, like reading articles and your hair just stands up because you're like, oh my gosh, there's no way this is here. Nobody else is talking about this. So if I come across here, and you're like, I've never heard of this. I feel like this it's because you're not spending 12 hours a day with the...a beast like Angie and I. She's uploaded over 20,000 articles to our Mendeley account. So I remember Dave Asprey when I listened to one of his podcasts. He's like, let me log into my Mandalay. I'm like, I wonder if his Mendeley is as big as my Mendeley, which is a repository of journal articles. So I'm super excited to get into this show. So that's my initial thoughts. That was my ramble. And I will, I will have everything else will be scientific data from here on out.Well, let's go ahead and start there. So we last on episode one. Basically, we broke down the various aspects of what is coronavirus? How is it directly affecting and we even talked about the stresses on resources. But now on today's show, not only do we want to leave everyone kind of with an idea on what they can do to supplement their own diet and the day to day things that they could be doing to basically improve their immune system as well as basically weather the storm better. Well, let's get a little bit more into the science of what's been some of the more recent data that I know that you and Angie shared because we've we've had a lot of conversations between last show, you going and doing now virtual clinic, me going and having meetings on transitioning the ASC over to possibly new ICU rooms, which is something we've never had to do before. So I'll let you kind of take it away there.Yeah. So you know, this is this is daily. It's hourly changing, let's be honest, and this is a global problem. So there's so many studies coming in what I think that makes us a little bit unique on the gut check project, is what we're doing is we're looking at the the data being published right now. 2020, late March, everything's been published, but then because of trying to link it to the 2003 we are able to look at articles back then also, because the SARS COV-2 virus structurally is extremely similar to the SARS first virus the COV. So a lot of these articles are a transitioning like that, where you can say that this is this and then because of that the links allowed us to find other things. So, a lot of what I'm going to talk about is preprints, meaning that I have access to articles that aren't even in publication yet. But the scientists are so passionate about it, that they're just sending it out. A lot of it comes from China because they have the most experience. I believe that when we did our first COV files last week, I don't know what was their 160,000 cases, something like that. I don't remember.Yeah, they confirmed and that's that's a pretty important thing. So we talked about that last week to confirm just because we're increasing confirm number doesn't necessarily mean Doomsday. It's just that we're able to actually confirm that a number of people actually have it. However, it does become a data point that we need to reconcile with. And we will yeah, we can we can get into that. But I just want to tell you I just looked about an hour ago and right now, the confirmed cases are 577,495. Mm hmm. That has jumped a bunch. There has been 26,447 deaths. I'm getting a lot of emails from healthcare workers who, when these patients are funneled to one institution, like my hospital, that institution, those health care workers are putting themselves on the front line. They are, they are the heroes. They are defending all of us by taking care of this and I just want to say thank you to every healthcare worker that is working shiftwork, that is in hospital, because you are the frontline of this and many times you don't even know if the person you're treating has this extremely virulent virus virulent being very contagious. So thank you. Thank you. Thank you.Yeah, without question. Thank you. Now, I this is not a doomsday podcast at all. In fact, to the contrary, what this is going to be is a complete bright light on this whole viral pandemic. I feel like we have spent this whole time figuring or looking at data and piecing together things that will bring hope to everyone. And that's what this podcast is going to be: how do you actually protect yourself? This is based off science. This is based off a bench research. I understand that some doctors would say, well, we need a randomized placebo control trial. We are not in an era right now where we need to do that. I understand that that is ultimately what we want to do. But in this I just want to protect people with things that we know have been around a long time. It doesn't have a whole lot of downside. So I have a moral obligation to do this and to share it with everyone here.Definitely, without question.All right, so let's let's talk about transmission, some of the newest information that's been learned. So everybody if anybody's new to the show, if anybody's wondering like, Why in the world is gastroenterologist talking about COVID19? Well, everyone's talking about cobit 19. So, doesn't matter if you're human, you're talking about it, but it's actually specifically relevant to me. And some of the newest information is this is that we now realize that the virus can be passed both through droplets in your respiratory system, and it can infect your gastrointestinal system. As it turns out the h2 receptor that we believe the virus attaches to that most have agreed to that the highest concentration is in the stomach and the duodenum which is the first part of your small intestine. So if you are eating food, that somebody has cooked for you or that, or maybe you've well, somebody else has to have cooked it for you, and you eat it, the virus can then get into your body through your gut, we now realize that somewhere between 30 to 48% of the COVID19 cases are actually starting in the gut. And 85% of those present with anorexia, or they're just not hungry. What's fascinating is that when you and I were talking, and we were going over those numbers last week, I was like, why is that and then the very next day, articles have come out and it's made the news now, but we were talking about it last week, about how one of the early signs of this could be Anosmia, which is lack of smell, right? Ageusia which is lack of taste. So my theory is that those people that have that that precedes the symptoms by a long time, or not a long time, we don't really know but it certainly is one of the preceding symptoms. So when I'm walking into my hospital and they have to scan me and see if I have a fever, first question that I'm asking is, how's your sense of smell? Because that is now a screening tool. So keep that in mind. The letter there was a article published from my college, not my college, I went to but the American College of gastroenterology, which is the society that I belong to. There was a report from China reporting that cases with someone who had contact with her brother from Wu Han, so a woman shows up with a fever to a hospital. Her brother had come from Wu Han to stay with her. She gets a fever she shows up says my brother was in Wu Han. I've got this they do a CT on her. And she has the ground glass appearance of the classic COVID19Right.tested negative four times on the sputum. One of the doctors was savvy enough to go test her stool. They did an immediate polymerase chain reaction a PCR. Her stool is positive, her sputum was negative.So the sputum technically you're saying that they the margin, there was a she basically was a false negative, correct?She was a false negative on the swab that they did. They did a total once they got her diagnosed, they knew that they were dealing with COVID19. So then she became sort of a case study where they did like five more swabs on her all negative. So what we're what we're talking about here is that the gut so as a gastroenterologist, I'm telling everyone right now your gut is your first line of defense. And we need to protect that you can do all you can for barrier to avoid droplets to get it in your eyes, your nose and everything. But you still gotta eat and all these people that are ordering takeout and everything. somebody's preparing your food That's a route of admission. And then this is not to create anxiety. This is just so that everybody understands this. And then I found another study, shockingly, that showed that there was viral shedding in the stool. Five weeks after viral shedding in the lung went down. So they recovered from COVID19. And then a group of physicians tracked these patients and they kept checking their stool. Five weeks after being normal, they still had virus in their stool. And on the last show, we did talk about the fact that the virus can live three to four days on steel and plastic, it can live in the air for hours. So if you've got maybe what we're talking about here is fecal oral. And I hate to say that because everybody cringes when I say that, but that's how all gastrointestinal bugs get passed.Well, I think we should address it you know, you're talking about science to layman's terms. So If we're addressing things like, keep your six foot distance, etc, that has a lot to do with the droplet transmission. Everyone's been told and we've learned as children growing older that we should wash your hands after going to the bathroom. But specifically, if you're going to the bathroom and and you've, you've had a bowel movement and you certainly if you've known that you've had exposure to Coronavirus or COVID19 be certain to be diligent about washing your hands after you finish the bathroom, even more so than in the past. So if you've always been washing your hands great, it's now's the time to make certain that you're diligent in the process of washing your hands, keep your hands clean, because the fecal to oral transmission is a real, is a real problem.I got called by a doctor today who wanted my opinion. Very intelligent doctor and he was like, hey, man, what's going on with this? It's it's all hype, whatever and I I started telling him about this kind of stuff. I said, no, it's this is this is real. We all need to...education is the key to controlling your anxiety. Remember that we're not here to cause anxiety. What I'm trying to say is, the more you know about this, the more you can control it. And what what we're going to do is talk about how to protect your gastrointestinal tract. Yesterday in shavon saunas CBOE SOS summit, I discussed how unfortunately, my theory is that if you've got CBOE bacterial overgrowth, or any other gastrointestinal problem in your upper small bowel, you probably have a compromised tight junction that will allow easier penetration. So my job is to let's fortify your gut. Let's make sure that your gut is strong. So when somebody comes knocking, you don't open the door. That's all you have to think of it.Just a quick reset it when he says tight junction is being breached. He's basically talking about the barrier in your GI tract basically, it can become permeable allowing you to become more inflamed or, or ill. So basically he's saying if you have this issue, what we're trying to do is protect it so you don't have that problem.So you're gonna do this a lot for the rest of the show. Basically, I want to say things that because I have been so into the weeds reading just super sciency stufflike what he says when he says into the weeds, he means like he's going to drill it, no I'm just kidding.I just it's just rabbit hole after rabbit hole because you hear a term and you're like, oh my gosh, what is that gonna go down over here and this and that. Alright, so I'm just going to talk about one of the coolest things coming out of Germany is there are some scientists that have a new rapid test to diagnose SARS COV-2 remember SARS. COV-2 is the virus that causes COVID 19. SARS COV-2 is the coronavirus the coronavirus is a family of viruses, this is the ridiculously tough, virulent, you know, bad one that's creating this pandemic. So some brilliant scientists realized that certain flavonoids, or polyphenols have a very high affinity to attach to the SARS COV-2 spike proteins. So you always see that picture of the, of the of the virus they always had it shown with a bunch of those little spikes all over the place. That's how come, Eric, you told me this earlier that's why they call it the corona because it looks like aLooks like a sunburst. That's what it is. That's how I learned it long ago, but it was called Corona because microscopically It looks like a big, big sunburst.Yeah. So normally, the way that these tests are done to try and determine this, what they're talking about is a diffusion test or what's called an agglutination test, but what these researchers showed is that two polyphenols luteolin and quercetin have a very high affinity and an inhibitory effect on the SARS COV 2 virus, I'll say it again, basically natural products, natural molecules in nature have the ability to attach to the virus. And what these guys proposed is that normally, when you have a test like this, you have to have an antigen, which is a protein that the antibody has to buy into or in this case, what you would do is use a very expensive antibody against COV-2. So they're trying to do tests like this, but they're taking blood from people or animals, getting the antibody and then if you put your sample if the antibody attaches, then you know that you've got SARS COV-2. These cats figured out that natural polyphenols attached to it. So what they do is they put the sample in, they put some polyphenols, there luteolin and quercetin and then if it clumps, then they go, that's positive. If it doesn't, then it's just chilling. That's, that's mind blowing.Yeah. So essentially, what you're saying is, is these polyphenols made the SARS COV-2 virus nonreactive. The antibodies had no, they didn't discern it whatsoever. So it was a negative test.No. So what it is, is they didn't necessarily make them reactive or non reactive. All they did is they could show that they surrounded it and smothered it. So when they found this in clumps, they knew that they had SARS COV-2. So this is just a preliminary test to say do you have it or do you don't, you can extrapolate that it can be both diagnostic and therapeutic. Meaning you can look at this and say not only can you diagnose it, but there's a very good chance that this same type of polyphenol may treat the virus. And that's what these researchers basically said in their conclusion. And what's awesome is they said this could probably be done with a lot of other viruses because of the antiviral activity. Soit's very, very interesting diagnostic, I'm almost certain whether it's therapeutic or not remains to be seen. It certainly is a natural compound to, at a minimum run interference for the SARS COV-2 virus.Yes, so you're probably wondering, Well, why in the world did you bring up some obscure tests that isn't even out yet? Because what's awesome is, these are all like preprints. These are scientists sharing stuff around the world. And I can almost follow when one guy references another guy, and then they do a study. The studies that I'm going to talk about in the beginning are all bench research that is called in vitro. When we describe something in vivo it's one we give it to a human. Right now, the virus is so new the novel Coronavirus is so new, that everything has to be done in a lab first to see what could be potentially effective in a human. So keep that in mind because that's that's an argument that a lot of people will say is oh, well, there's no randomized placebo controlled trials on humans blah, blah, blah, we're not we're not we need to stop something first. Need to control this and then we can flatten the curve. Get that R0 watch this, watch the first episode because we get way into the R0 thing get that R0 down, and then we can go there. So, dude, what I'm going to talk about is absolutely nothing short of extraordinary, extraordinary. And these are drugs that President Trump is telling all these private companies. I think there's like last week there was 35 different companies trying to produce products against this. There's a lot of them are called protease inhibitors. A protease inhibitor is an antiviral drug that we, that got discovered during the HIV era, where what they do is they block the virus's ability to grow up. So in other words, a virus tries to release his buddy. And then the protease inhibitor says, nope you're gone, and then they kind of kill the new viruses being produced. This is, and this, this prevents the viral cells from growing and maturing. And according to the scientists that are looking at clinical trials, they're trying different protease inhibitors to block SARS COV-2. So there's clinical trials going on with protease inhibitors that we know So, the first article that I want to talk, this is the title of the article, and I will let you, layman for me. Okay. All right. This is the actual title of the article. It is a pre print article. So it should be what we're talking about here. When I say pre print is I'm giving you information before way before it's going to make the news way before. So this is why this is a hopeful podcast, very hopeful podcast. Potential inhibitor of COVID19 main protease empro, from several medicinal plant compounds by molecular docking study.Okay. Well, let's see, it sounds to me like what we're trying to do is use a naturally occurring substance, to eventually stop a virus.Through the protease inhibitor method,Well you said layman's terms last time my neighbor said protease was never. You're right. Yeah, yeah. You and I have different neighbors. My neighbors and I talk protease all the time. I'm surrounded. All my neighbors are infectious disease doctors. SoI know it. That's, that's what my takeaway is from that is, we are going to find how nature can allow mammals, humans to consume a natural compound and stop a virus from spreading.Yeah, so correct. So what they did is a researcher in China was able to successfully figure out or crystallized the COVID19 protease, that's the key step. And these guys took that person's science and said, okay, what is a potential target, to stop that protease? And they develop this very complex, cool study where they could show the binding energies. So when they say docking, the cell has to dock onto another cell. And then if it infiltrates, then if you give a protease inhibitor, it can't move. So they want to know how tight it binds to that protease enzyme. And what they figured out was they looked at three HIV protease inhibitors and 11 polyphenols.So and then just to reset into layman's terms, if you're trying to keep track of the the words, the way that I kind of have charted this together is a virus uses a protease like a key. The protease is the key for the virus to infiltrate and then deposit this mRNA so it can replicate what Dr. Brown is talking about doing is how can I stop their key from working? How can I make it so that this virus can can't use the key the protease to where the virus is using that protease to break down the protein so it can inject its RNA?Yeah. So the viruses, like we talked about before, are amazing parasites, they have to get into a cell, they have to replicate, they take over the cell, and then the virus starts going around. So these guys knew that there's three they looked at three HIV proteases. And then they realized that there's naturally occurring molecules in nature called polyphenols. And they demonstrated that the drugs and these 11 polyphenols appeared to have potent attachments to the M Pro with the M Pro is the protease on COVID19. Therefore preventing the virus from replicating their fin...their final conclusion was like all good bench researchers. Further research needed to do human trials.Sure.So they have a model with the virus and these polyphenols bond tightly. Super cool.Yeah, no without question. So essentially, they're saying if we can find a way to stop impro from unlocking the cell, then SARS COV2, or the coronavirus cannot infiltrate these cells.Yeah, so that was really cool. And then mic drop. Another study comes out of this one's out of Turkey and Pakistan. And I'm going to reach out to these researchers. They were kind enough to list their cell phones and emails on this study. I'm not sure that they meant to do that. Doesn't happen all the time!I'm gonna I'm gonna hit them up and I just gotta find somebody that can translate for me if necessary. We're going to do this. Their article title is identification of potent COVID19 main protease. Now you know what a main protease is empro. These guys took the research from the person that discovered it and did the exact same thing as these other guys did. So identification of potent COVID19 main protease inhibitors from natural polyphenols. And in silico, strategy unveils a hope against Corona. What? These guys saw that study and went, wait a minute polyphenols seem to be the way to go. This could be a new hope for Corona. This is what these guys are talking about. It's out of two very prestigious academic centers in Turkey and Pakistan. These guys are absolute beasts, I should say, guys, I'm just assuming there's probably women on the team also, that's rude of me to say these guys, but these scientists are beasts. So since its main protease was figured out, and remember I'll say it one more time, the protease allows the virus to grow and replicate. That is why we figured it out for AIDS. So they did a study where they looked at 26 polyphenols and one prescription protease inhibitor called nelfinavir. OkaySo these guys had the guts to say let's see what happens when we compare polyphenols to the current antiviral therapy that we use for AIDS. These results are absolutely shocking, Eric, this is I cannot make this stuff up. This is where my skin my hair just starts bristling. Basically 24 of the 26 polyphenols bound tighter to the COVID protease, then the prescription drug did. I'll say that one more time. It bound tighter than the drugs that we're thinking of using. Nice.And I'm really having a hard time trying to not be enthusiastic here and try to be scientific. I said it's gonna be very somber, scientific thing, but I'm just now um these are lab people. And these these guys, I could tell by the writing that their that excited I mean, when, when the title says, you know, exciting new treatment for Corona like these are bench researchers that if the numbers make sense. So this is not something to say that 100% this will work in humans, what we have is bench research stage one, stage two is to work to a human pilot trial, stage three is to do a randomized placebo control trial and so on. But this is so exciting to see that this is proven in a lab that these 24 out of 26 polyphenols and what this tells me is certain polyphenols did slightly better than others, as best they could tell. But the molecular mechanism is very similar it all is and then what they determined was it was a dose dependent, so you had to have enough of it to do it. So pretty wild.I don't want to jump too far ahead. But questions that are popping up in my mind are going to be number one is binding for the most part, preventing the virus from carrying out its activity. Because, you know, you don't want to just bind and be happy that you are bound, and the virus can go on. And the other question would be, what, what are the categories of polyphenols that happened to perform better than others? And do they all still you said 24 out of 26. So we know that two probably aren't ideal, but what were the categories?No, no. 24 out of 26 outperformed the prescription drug. The other two just were about at the level of the prescription drug.Thank you for the correction. So 26 bound.And I just want to clarify one thing I'm you and I are not virologists. The concept of protease I think, is more of a replication thing than a that's how come it works so well to stop the virus. I think it's more of a prevents the virus from replicating as far as binding. There's some different science with that. So just and I'm not a virologist, I'm a butt doctor. So um, so then of course that starts, you start going down some crazy pathways. I found another article that identified myricetin and scutellarein or something like that, which are polyphenols. Somebody else did a study as a novel chemical inhibitor of the SARS coronavirus. by blocking the helicase. The helicase was described as something needed to replicate. Yeah. So what I meant by I've just been exhausted is I read these articles and then of course, you stop. And it's like, I gotta go look that up. And then you end up going down a helicase pathway and I was just like, oh my gosh. The science doesn't matter. What I'm saying is there's people that are now looking in 2020, because they're doing the same thing I'm doing, they've seen the data from 2003. And now they're trying to see if that works on SARS COV2. And it appears it does.Well, is it a helicase? Isn't that an enzyme? Yeah, we hear about the double helix or whenever you see DNA after it's been scripted, and you see the winding, you know, mirrored image. Helicases, the enzyme that allows the assemblage of the mirrored DNA if I if I remember correctly, I could be wrong on that.So that is, that is med school year two USMLE. was done with that. As long as it passed. Um, here's another super I think I get pulled a gene like they pulled the gene out or something like that. Sorry, I don't wanna get sidetracked. I'm just kind of like...I don't know. I mean, dude, it's like clearly We're gonna have to get a virologist on to explain all the terms just say you guys are idiots. You're using the terms incorrectly. Let me explain it to you cool. I I welcome any virologist to to help us get through this because this isn't our thing. I'm trying to figure out how to take care of my patients. That's all I'm doing right now. Speaking of that. Another study titled small molecules targeting severe acute respiratory syndrome, human coronavirus. These guys looked at over 10,000 compounds, including over 500 protease inhibitors, 200 drugs, 8000 synthetic compounds and 1000 traditional Chinese herbs. Of all of them 50 were found to be anti SARS COV not COV2 anti SARS cubs. So this was a study done after the original SARS outbreak. Okay. Two made the best cut, one being a molecule called Aescin-AESCIN, the extract of horse chestnut.Horse chestnut. Yeah. Wow.And the other is a drug called reserpine which is a high blood pressure drug used in Europe. Huh 10,000 different compounds and Aescin the extract of horse chestnut is there. Okay, that's cool.Yeah, it's a polyphenol,that is a polyphenol/saponin. And we know a lot about that you can go on atrantil.com and learn about Aescin and if you want. Pretty wild. So that's my this is where this is going to go. We're going to be able to figure out how to optimize the appropriate polyphenols to protect your gut to protect your health. Those are astounding studies. It's I mean, I'm just fascinated. Alright, so everyone knows this. We developed atrantil. Atrantil are three polyphenols I have been into the science of polyphenols for over 10 years now. So now that I'm looking at this, this is not a sales pitch. This is a oh, my goodness, the molecule that I've been studying for 10 years, which is super complex and all this, I'm finding scientists around the world studying it and having positive results. That's what this is about. Nothing more.Now, here's here's the interesting part, though. So if it happened to only be a prescriptive drug or something that were synthetic, it would almost be completely imperative that that multiple rounds of trials and testing be carried out. Simply for the safety profiles so that they can be safely used somewhere. The exciting part to me is that what we're talking about is something that is already naturally occurring and is safe for us to begin to utilize as kind of like internal PPE. That's how I think about it as a frontline worker...Say what...say what PPE isOh sorry, personal protective equipment. So that was...Yeah, so one of the issues that if you're not in healthcare, the term PPE is being used because we're all running out of gowns, masks, gloves.Everyone is and it hasn't even hit our area nearly as intensely as it has like the northeast or the west coast, we're we're running outAnd you you as essentially, somebody who controls airways and you have to intubate people, you aren't so in the line of fire, so to speak, you're on you're that frontline person. You're one of those if you're an ICU nurse, if you're an anesthesiologist if you're a respiratory tech salute all of you, because you guys are right there getting into it. Now, some would say, hey, you spent the first half of the show talking about gastrointestinal issues. Yeah, I salute my gastrointestinal colleagues as well. Because it looks like we're in the fight now also.Definitely. It's just it's the takeaway, though, from those those studies, those reviews that you just had, though, Ken, don't you think that the exciting part on top of we think that we may be onto something is that people can begin to take action now with at least the data that is applicable, it's safe to use it worst and at the bare bones worst if someone happened to just simply start eating more polyphenols that they would take in from fruit yet, if it didn't work? Well. They're still getting great fruit and fiber etc. There's there's really no downside to applying a little bit of this, this reviewed science as we as we wait to find out that these are actual adversaries to the coronavirus. Correct. So polyphenols if somebody's like man they've been talking about polyphenols this whole time, what does that polyphenols are the molecules that make vegetables and fruit, colorful, it's on the skin. Those are the molecules found heavily in the Mediterranean diet. And those are the molecules that we now believe are anti aging anti inflammatory molecules. That's how come that we've been studying this so much. So I've been using it for gut health. So if at the very least, when you eat, make sure your plate is colorful, everything should be colorful. If you can imagine when you go to McDonald's and get your whatever it is. thing you lay it out. It's got a monochromatic tan across the...Very yellow...very yellow plate.Very yellow plate. You want to have green reds and purples and When you're doing that you're getting your polyphenols in knowing that the polyphenols could potentially help this. So that's super make sure that you at the very least do this. We know that they are very potent antioxidant, anti inflammatory antibacterial and antiviral. Yes. data to show all of that.Yeah, definitely. No, that's that's it's just a great takeaway to know that you can actually possibly be taking some serious action for your benefit and your family's benefit today.Yeah, totally. Um, so let's kind of get away from polyphenols and talk about what else you can do. But you're gonna hear a recurring theme here. It's, it's or fortunately, Mother Nature knows how to do this. And you got to take advantage of that. So let's talk about something so I've been getting tons of emails and patients calling in everything, what do I do for this and that, so let's talk about zinc. Why is everybody saying zinc? Why did they get buy get bought off the shelves? Why is it there? Well, zinc, if you're low, then your immune cells won't function well. And intracellular zinc can block the enzyme that allows the virus to replicate, which is an RNA polymerase enzyme. One more time, you take zinc in, very small percentage of it gets put into the cell, where the zinc then just goes, come on now, and they just starts working on the virus's rep replicating system. That's how it works as an immune product. And so zinc is an essential mineral that we need to take in, but you got to get it into the cell. So some scientists realize that we have to figure out how to get more zinc, intracellular. I got to quit touching my face, I just realized I'm messing up my hair and I...I've been doing it the whole time.Yeah, I'm realizing just I mean, I just get I get, I get excited about this. We know that zinc can inhibit, specifically Coronavirus, RNA polymerase activity in labs, but it has to be intracellular. The problem is that once it's in the cell, it can do that. But it has to get in there. And that's difficult to do. Scientists have realized and I keep saying scientists have realized I'm just referring to other smarter people that have done these studies is what I mean. So other people that are smarter than me have figured this out that it needs something called an ionophore to get in. So it's like a fast pass or it's a it's there's a security guard at the cell door, and zinc like a my humans eating all kinds of zinc. I'm here to help out and the security guards like you need to come in with somebody you need to have a VIP with you. Well, they're looking at different things that work as VIPs and as it turns out, flavonoids which are In the class of polyphenols, not only act as antioxidants, but appears in this particular study that they drove zinc into the cells, then they showed that with mice, they could actually show a rapid increase in intracellular zinc, when the zinc was taken with polyphenols, or if you're taking polyphenols. And also taking zinc doesn't have to be the same time. And they did this through very complex fluorescent staining. So that is super wild. You need zinc, but you need intracellular zinc. So really pretty, that one kind of blew me away also. So I just got done talking about two bench studies, where they work as protease inhibitors. And now I just showed you how polyphenols can work as zinc ionophores. That should be like enough, and we actually have more stuff to talk about, which is nuts. SoSo just in just a quick aside if if you have a diet that's comprised of good Healthy meats. What else? Beans probably seeds, nuts, various nuts. That's where you'll find naturally occurring zinc or...Cashews. Cashews are a big one.Definitely there's there but there are definitely some zinc supplements out there. So as a as Brown lays out different things that you probably could take at a molecular level, I'm going to try to keep up and say, places where you can find them so that you can incorporate them into your daily intake of foods.Yeah, so unfortunately, I'm just geeking out on this. So if you if you figure out how to say, Well, if somebody's sitting there going, Wow, where do I get it? Yes, absolutely. Thank you. Thank you for doing that. Um, something else. There was a study that came out of Korea, which showed that by certain probiotics in vitro, they could actually stop the hearing metabolism which this particular virus uses to get energy and one step further. That was in vitro then I found an article that showed that polyphenols work as an antioxidant by blocking xanthine oxidase which is part of the pureeing pathway. So the energy gets taken away from the virus as well. So that's super geeky. It's like, wow, it's like almost like every time somebody chooses to do a study on these polyphenols, they're finding a positive effect. We have gotten sicker since we have become industrialized, and we have refined foods. Having soil with rich and minerals and everything and eating the seasonal vegetables is probably a very effective way to protect yourself from a lot of illness. Not trying to say specifically COVID19 but doing that is probably a great way to protect yourself from a lot of things.Definitely hundred percent. I don't have a whole lot to add to that.Alright, so I'm tired of polyphenols, if I could ever say that I've only been talking about 'em for 10 years. So, alright. We did say on the first one that I want to give some recommendations about things that I'm telling my patients that I'm doing that my kids are doing that everyone that I think there's some science backing this. So other recommendations I'm telling I'm a big fan of fermented foods. I don't understand why but Germany continues to have this profound or I haven't, or a very a much lower death rate than the rest of the world. And I always laugh because I'm like, Is it the sauerkraut? I just keep coming back to them because the sauerkraut is it the beer. What is it, but so fermented foods, especially those that have Lactobacillus plantarum and bifidobacterium and lactobacillus generally will actually have been shown to have some antiviral activities. So now's the time to go out and get that kimchi now's the time to go out and eat that sauerkraut and that kind of thing. As you know, I'm not a huge fan of probiotics based on the science because not that it's there they're bad. But the science just isn't there and I don't want people spending a whole lot of money on things that don't work. I'm a big fan of polyphenol wrapped probiotics, kimchi, sauerkraut, things like that, because the insoluble cellulose, in my opinion probably works as a vehicle to get that bacteria to the colon. So, fermented foods. I'm kind of a fan of right now. We discussed zinc and vitamin C is an essential micronutrient that works as an antioxidant. What you will hear online right now and in forums is that studies in humans are extremely conflicting. So you have to go a little deeper than that. And that's the knee jerk that every doctor will say as well. The studies don't show that. I want to say this. Angie and I discovered an article with mice genetically grown, that do not have the capacity to make vitamin C. And then they took mice that are normal and they exposed...they exposed both groups to influenza, those without vitamin C died. Those who had it had a lot less inflammation and a lot less inflammatory cytokines. Right now in China there is an ongoing study where they're looking at giving IV vitamin C. So if you want to compare old studies that talk about the rhinovirus and does vitamin C help, what we know is looking at animal data, vitamin C is extremely important. And the reason why it's important is that we know it down regulates and inflammasome, inflammasome called NRLP. What that is, is we know that people are dying from what's called a cytokine storm, which is where your immune system overreacts to the virus. It starts with an inflammasome and then it becomes a domino effect. And just start turning on all these cytokines. So it also helps regenerate glutathione, which we're going to get into. And one of the only problems with vitamin C supplementation is if you take too much it can create some gi upset. When I was on Dr. Raun's summit, Dr. Lundqvist, who went on before me who's an expert in this did discuss something really cool, which I was unaware of when you are sick, you increase what's called your glute one receptors. So you will absorb more vitamin C that you take in, so your body knows when you're sick. So if you're not sick, and you're taking tons of it, you're probably gonna have some gi upset. If you're sick and you take a little extra, you'll probably be fine, which I thought was really cool. So I love learning from other really smart doctors. Next product everybody goes on vitamin D. Yes, we know that most people in the United States are vitamin d deficient in a systematic review, vitamin D appeared to protect individuals from acute respiratory infections. Vitamin D is expressed on both B and T cells, which are our immune cells. And what it does is it can modulate your immune response. I'll say that again, it can control your immune response. So it almost works more like a hormone in that it tells your body to not overreact, which is something super important. And low levels are associated with increased autoimmune disorders and increased infection rates. So looking at a different study, it looks like that taking high dose vitamin D on a weekly basis, which is what many doctors recommend, is not as effective in this particular case as taking a daily vitamin D supplement. So I would recommend somewhere around 1000 milligrams a day. Most supplements come in the 2500 to 5000 range but I'm on it and my family's on it as well. So super important to do thatThing here so vitamin D foods are lot of your oily fishes, dairy milk cheeses and I think some of the greens like collard greens and mustard greens I think have vitamin D and of course don't forget you need to convert it. Get sunlight, get sunlight every day.Yes, go out for walks. walk your dog Get out right now is a great time to get out. And yeah, thank you for saying this. I should have started with everything. I'm not saying get out. I should have started from the very beginning. Don't go out and buy a bunch of supplements. Try to eat the diet that has these ingredients in them first. Supplements supplement a healthy lifestyle, but is no substitute a healthy lifestyle. So that being said, Yeah, so thank you for bringing up those foods. And I will throw this at you now. A diet in healthy phytosterols. Phytosterols are vegetable oils that appear that they may block the binding site of these different Coronaviruses. In other words, the ACE-2 receptor that they keep talking about in the news uses cholesterol to bind to what is called a lipid raft and then that lipid raft of the virus binds to it and then it kind of slides down. I always think of it like the way that they describe those inflatable rafts when a plane lands on the water they come out and people come out that's how I think of it.Don't you want to get into a situation where nobody gets hurt but you get to pull it I always wanted to inflate that stinking thing.So a diet high in phytosterols. So things like you know what I'm gonna beat you to this one because I had that I actually had to look this up phytosterols isn't something phytosterols are very high nuts, legumes, grains and fruits and vegetables. It's a common theme here. We keep saying the same thing over and over. I mean, don't eat at McDonald's, eat your fruits and veggies, and healthy fish and things like that. And two more. And then this is this rounds out my list of science backed supplements that I can, I can at least lean on some data. Because there's a lot of things out there that people talk about. That is not my specialty is not my that I have not had a chance to get into. But n-acetylcysteine is something that I'm a big fan of, n-acetylcysteine (NAC) has some mucolytic properties. And in a 2017 meta analysis, meaning in 2017, they took all these studies, they found that treating patients with NAC NAC and n-acetylcysteine led to shorter duration of ICU stays in acute respiratory distress syndrome, which you geeked out on on the first episode explaining all about ARGS. So go back and watch the first episode because this is Eric's specialty, keeping people alive with that kind of problem. So salute to you for doing that kind of stuff. And Chinese protocols right now Chinese hospitals are using n-acetylcysteine as standard treatment when somebody comes in with coronavirus. It also does something really cool it increases glutathione levels. Glutathione is one of the most important cellular antioxidants. So what that does is it is a potent cellular antioxidant, and we need this for cellular health, cellular health kind of funny the guy that went on after me was Dr. Dan Pompa, who I who I love and his his whole his whole mission is cellular health, which is cool. A study looked at people with community acquired pneumonia, and they randomized them to either conventional treatment which would be antibiotics, and...conventional treatment antibiotics plus NAC. And what it showed was the NAC group healed quicker and had lower inflammatory markers. I'm currently taking like 600 milligrams BID, the dosages were all over the map in all these studies, but wow, okay. There's studies out here that show this and they essentially are you and I have talked about how NAC helps with alcohol metabolism, but this is a whole separate method. This is getting the glutathione and then ultimately, I'm recommending melatonin as well. Melatonin is a potent antioxidant. But one of the reasons is to make sure that you have everything functioning well. You got to sleep. During these very stressful times. You've got to get...try get eight hours of sleep. Please, please, please, please, please. And this is nuts. Kids don't seem to be affected by this virus and one of the speculative things is that kids have much higher melatonin than adults as we age we decrease our melatonin so over the age of 70 you have much less melatonin. I read an article describing how the higher melatonin that you have you in your NLRP3 inflammasome. inflammasome yeah.Is down regulated by melatoninNice.You have your highest melatonin traditionally between ages one and five. And as we age it decreases and if you do not have a high melatonin you are susceptible to a cytokine storm cytokine storm as we talked about is your body overreacting. So one last time did you write those all down Eric? Can you...I did.Tell everybody what what what I feel science backed things may help during this pandemic,In addition to a healthy diet of polyphenols or supplementation with polyphenols and of course we know where you can get that with Atrantil. There is strong science to suggest that you should couple a polyphenol diet with zinc, vitamin C, NAC or n-acetylcysteine, vitamin D, phytosterols, and melatonin. You can get zinc and NAC from meat, eggs, etc. Your vitamin C obviously comes from great citrus fruits and vegetables. Let's see here phytosterols there's tons of plants and seeds that have that in it and of course, if you don't produce enough melatonin that is a very common supplement. However, I will say though, that you want to be selective on probably where you where you buy melatonin that seems to be one of those. Oh yeah, yeah we that's a whole separate show. I actually pay to belong to examine.com and consumer labs.com. I'm a user because I go there and I have them do the analysis. That's a third party analysis. So any of these supplements make sure that they're third party analyzed. So those are the ones that I can sink my teeth into really deep and go, this clearly looks like this. Now, there's other things that a lot of other people will be like, oh, well, what about this? What about this? What about that? I'd like for instance, broccoli, broccoli, or sulforaphane? Sulforaphane comes in broccoli sprouts. I found some articles that show that coronavirus may decrease your NRF two pathway which is the pathway that leads to inflammation and that so I'm also taking that we know that that actually has some antibacterial effects. Shivan and I got kind of deep into it yesterday in the CBOE summit, where we talked about how I'm using that in my CBOE people as well. I'm having pretty good results. So that would be one that I can't really say, I've looked at the science, but I'm seeing anecdotal evidence and it's probably good for you anyways. So if it has some ability to help with this infection, that would be awesome. And we know that like, CBD attenuates the immune system, so it at least gets you back to balanced immune and neurologic systems. So I'm obviously a big fan of that. And that's you can go to our website and take a look there. I'm not saying not recommending it, that this is any type of cure treatment or benefit to this particular pandemic. I'm recommending to make sure that you're doing everything you can to try and improve your immune system.Definitely, if you're if you're a frontline health care worker, just be certain that you're doing all you can to take in a good diet. Be certain to get your exercise and know that you're probably hustling all over the hospital floor or OR just taking care of patients even if they don't happen to be COVID patients. You want to be certain that you're keeping yourself nice and healthy in that environment, get sleep, no matter what just prioritize sleep, your immune system just will never be as strong as it possibly can if your body is not getting rest, so sunlight, sleep in addition to a good diet, it will make for a much better outcome in the long run for certain.Definitely, we and we won't stop these installments for the COVID talks until we we more or less feel comfortable that we're heading that direction. I will say that we've been put in contact with an infectious disease doctor in the Department of Defense that actually he probably can't join us live or recorded on the next installment of of the COVID file. However, he is going to vet some questions that Dr. Brown has sent his way. Basically just just read his responses back. Yeah, absolutely. And we want to, once again, thank everyone who's worked in the hospital systems working, shift work, or EMS people. You guys are the true heroes because you are doing shift work you affect your sleep cycles, you're getting a lot of stress. I know I've talked to some emergency room physicians who are seeing other issues with this shut-in like, unfortunately some more domestic abuse going on and things like that because people are forced to being you know, the finances are tight, and the the quarters are tight and everybody is you know, struggling but hang in there. We're gonna get through this and what I just got done telling you even if you even if you're sitting there like it's been like what I like turning it because you guys like to joke around what do you do? I was just nerdy. Just bottom line is, it looks like we're heading in the right direction for figuring out how to how to stop this.That's perfect.Got a little bit different perspective as an ID doc, as well as tending to the pediatric side in combination with ID. That said, though, it probably won't be a full week until we come back with the next installment simply because we're finding some more time to dedicate collecting research and kind of really getting it organized. We certainly appreciate everyone sharing the last installment. Hopefully, we'll do the same here. And when the show notes for this one on the YouTube YouTube presentation, we'll be sure and list all of the supplement lists that that Ken laid out for you. And I don't know, it's a pretty powerful episode. I hope that people can begin to arm themselves and I think that the next time we're going to have some some good feedback and start rounding the corner to better days.Yeah, yeah, definitely. Well, appreciate everyone tuning in. appreciate everyone staying home. It is real. We still have to practice at least right now. What's the you know we're in March. We're still practicing social distancing.I almost forgot and I'll put this in show notes also, if you're looking to just make a difference in your community, Ron Lynch is a really close friend of Dr. Brown and I his name as name is Ron Lynch. He just started intellihelp about a week ago or a week and a half ago and intellihelp and intellihelp.org IntelahelpHelp. HELP. Intellihelp can be founded intellihelp.org. And intellihelp is intellihelp on Facebook. What it does, it's a very free service if you are available to give and help in service in any way. They've done really, really well over the last almost 10 or 15 days of if a woman needs diapers to take care of her kiddos and she doesn't want to leave the house. She just basically posts it someone who happens to be coming back from grocery store drops it off someone that kiddo needs to have an availability to have a free lunch dropped off because they're not getting lunches from school. Yeah, intellihelp is there to serve those people and to give you the ability to give back to them and trust me, if you feel a little bit down in the dumps, you'll feel a lot better once you're able to help somebody else and you feel like that you're notThat's awesome. That's awesome. So how do we prevent like a you know, our partner Mike Logsdon from gettin' on Intellihelp said I need a Guiness delivered to my house right now.There's no way to prevent that from happening because because Mike may need that Mike may need that Guiness. That is true. I have a feeling that as close as you live once you get on intellihelp Ken you'll be...Loyda goes where are you goin'? Mike needs his Guiness again.There's nothing I can do. I'm going to drop off some diapers and some can some some black aluminum cans at Mike's house.Yes. I love that. Awesome. Well, Ron Lynch, kudos to you. That is badass. Awesome. Thank you for being part of the solution.Definitely, definitely. All right. Well, I think that's the the end of second summit will be like I said it won't be a week until we get the third in. And we'll get a little bit more regular, a little bit more frequent as more news evolves. We're just kind of setting the stage here. But yeah,And if everyone can just comment, and let me know if you want it this sciency not so sciency. I mean, we're, we're, we're all learning as we go during this, because the because everything's coming out by the hour. Yeah. And we have the ability to go as deep as you want. We have the ability to find stuff that is not in print yet. And that's what I like when we're talking about stuff. And then three weeks later, the news we were talking about the anazmio well before it even made the news.Yeah. Well wondering if it was true, right. Remember that you said have read this. I have no idea if this is even accurate. I mean, between that and people shoving hair dryers up their nose, we didn't know which direction to go.True. Heat up the nose. That's right.Don't do that. It's terrific idea. All right. Well, ladies and gentlemen, thank y'all so much for tuning in and sharing a next installment here rather soon and they may not all be nearly this long, we may have some shorter...How long was this?Right in an hour? What? Yeah.It felt like 10 minutes.It's just a lot of info. Well, thank you Ken and, Paul, thanks for of course for putting everything together. We will see y'all next time on next COVID installment. I'm Eric Gregor. That's Dr. Ken Brown here with a gut check project. We will see y'all next time.Stay safe, everybody.

Living Generously: Ron Klabunde of Generosity Feeds

Play Episode Listen Later Mar 12, 2020 69:25

All right, it is now time for episode number 35. We are here at the Gut Check Project. I'm Eric Rieger with your host Dr. Ken Brown. We've got someone special here today right between us.Well, we are in some place special. We are.We're not in our home base.We aren't in the home base.We are in a basement in Austin. We are.Because we heard that this special guy, Ron Klabunde, the founder of Replenish Foundation and Generosity Feeds which you and I are huge fans. Definitely.You took your family to go do that. We went and did that. And what he's doing is amazing. And we decided to do a mobile show here. We had the opportunity to track him down. He's busy. He's an important person.Ron. Obviously we're going to introduce you-the founder as Replenish Foundation as well as Generosity Feeds but we came down here specifically for an event that you're hosting. Without further ado, Ron, just kick it off and then we're going to after you tell us what we're doing here today, we're going to back it up on how you even got here.Sounds good. So tonight, we are bringing the who's who of Austin together highly curated group of 100 people. And basically we're going to party on purpose we call it POP Austin "party on purpose." Too many parties happen it's just a party, right? What if we bring some meaning to that because all of us are looking for more meaning in life. So we've got the top people in Austin coming together to party on purpose. Obviously we know when the right people are in the room magic happens.Definitely. Happens from a business standpoint happens interpersonally. And then there's the purpose side. So tonight, now what you guys don't even know is that you're showing up and everyone there is going to have a chance to create about 2,500 meals for local kids struggling with hunger. And then flow in the middle of the party. Oh, that's awesome.That's awesome. And then on top of that, we're working to raise $60,000 tonight to help to help feed 50,000 children across America who are struggling with hunger and empower 64,000 volunteers that we're already working with, as an ongoing force for good. So there's our purpose side: party on...Say that one more time. So tonight, this party that we're all gonna have fun at, everybody's...Live band...everything.It's gonna be entrepreneurs coming together, talking, sharing ideas, but you're going to feed how many people you're going to raise how much money and this is a party on purpose. I love that. Yeah, yeah. So there will be about 2,500 meals created tonight throughout the course of the night. And then, and then we're raising money to help feed 50,000 children in 29 states across America, and then empower our 64,000 volunteers is an ongoing force for good.So we can't emphasize this enough here. So Ron and...Ken and I met Ron around a year ago through the Baby Bathwater network. And not long after we ran into each other you invited Ken and I to participate in the Dallas Generosity Feeds and we looked at it and we thought, have no idea what this is. And just like Ken said, I was able to get my family-his was actually out of town playing tennis. But loaded the kids up, met Ken. My wife and I we got together and we packed 11,000 meals in about an hour and 20 minutes.That's dead on.And it goes to it went to all those kiddos who simply correct me if I'm wrong, but they don't get meals on the weekend. They happen to be on a free lunch Monday through Friday right? But they don't have anywhere to turn for the food so kind of tell us a little bit about Generosity Feed.So, Generosity Feeds is kind of our...it is our premier initiative. It's what gave us influence and credibility across the country. It's It's why we have 64,000 volunteers today and we've helped feed over 170,000 children across America. I mean, it's crazy what's happened in...with this deal. And I can certainly give you the backstory on how that even started at some point here but but yeah, you came to our event in Dallas, by the way, our first event in Dallas.Oh, nice. Oh, was it?Yeah, our first event our first event there with you. And 11,000 meals created in less than two hours. You probably had about 300 people at that one event alone.That was...we were packed.So that was the thing that I was super impressed. I showed up. Everybody there showed up kind of deer in the headlights like, what do we do? And you just you have one thing in common? We're all here to help. So people are like, Hi, I'm Joe. Hi. I'm so and so. These are my kids. This is my wife. He's like, yeah, we're here to help feed some people. Everybody had the same mission. It was so cool. Because suddenly you have a purpose.Yeah, a shared purpose. A shared purpose. Yeah.Yeah. Well, and the beauty of this is it's these 300 people are coming from all aspects of the city. This is the business sector coming together with the nonprofit sector coming together with the local schools. And you probably even had some, some some politicians standing in the room. It but it goes further than that. Then you have people of all ages. You have kids with you-kids as young as three, sometimes moms or dads carrying the child on their chest, right as they're creating meals. And then we've had we had a lady up in Washington State 97 years old, helping start so it's crazy, right? But then it's beyond age, then it's it's the social economic difference. Because Ken you very likely were standing next to a single mom, whose child three weeks later was going to receive the meals that you were creating. Really? Yeah. And you didn't know it.Did not know I talked, everybody that was standing next to me. We formed now the beauty is Generosity Feeds does a great job of the logistics of getting the food that's there. This is how we're going to pack this how we're going to do it. It's a well run business. Absolutely. It's a very well run business and we're going to get into this because to have a good nonprofit...You better have a good business. You better have a good business. Well and I'll even add that it's good business for businesses to be a part of and I think I've shared this with you in the past and Ken you knew it but when we went to go and be a part of Generosity Feeds and of course I'm gonna say this several times because if you're ever interested and Generosity Feeds is appearing in your neck of the woods. Gather your friends and your family and go be a part of it. You'll spend two hours helping out tons and tons of kiddos who just simply need a meal.Having fun. Music. Yeah, music. Dancing. Dancing.It was fun! But, I had never been to a Mod Pizza and mod pizza happens to be one of the sponsors, title sponsors of everything Generosity Feeds does. Because of their involvement and the the fun and the giveback opportunity we had, I've been to Mod Pizza now probably eight or ten times in the last year and I'd never been there before. So I connect with the the business aspect of wanting to be a part of something good. And suddenly I found a good and worthy business that actually has gluten free pizza that my wife can eat. Because so it's, there's there's lots of reciprocity, if you want to be a part of an organization that gives back so if you're, if you're a company, pay attention, Ron's who you need to hook up with if you're interested.That's why that's why we're here. Atrantil KBS research as a company, we're here to support you. Because we are trying to heal people's guts. Yeah. And you are trying to feed people.And keep them full.And keep them full. And we want to be involved with a company like you. And I'm very honored that we're sitting here. I'm very honored that we have the ability to be in Austin, that we're going to be part of this. Thank you for inviting us. But I'm also honored that we work for a company that decided to do this together. So shout out to Chuck and Mike and Brandy and everybody and Anthony, everybody else on our team that said yes, go down to Austin. We're going to support thatThat's right. Absolutely. So, we've talked a little bit about generosity feeds and I believe you said it's a subsidiary of the Replenish Foundation. Correct. But there was a Ron Klabunde long before Replenished Foundation and Generosity Feed. So, where are you from? How did you get to...? Where my rear end is. Yes, yes, yes. That's where I'm from.Oh, yeah. So Ron is hilarious with with lots of cheap jokes where his rear end is where he's from. And, but Where, where, where do you originate from? How did you get to where you are now I know that you have a history of being a pastor, etc.So so yes, I was a pastor for 21 years. And in my own journey, as I've shared with you, I just became a little disillusioned with how local churches were talking about loving God and loving other people, and yet really weren't partnering with businesses to make a difference or really, I mean truly partnering with church, schools to make a difference or even other nonprofits they they tended to want to keep doing ministry on their terms. And I'm looking at this and I'm going, this isn't about what a church should be doing to for in a community. It's what a church should be doing with a community, based on what a community needs. Why are churches inviting people to come to them to meet their needs on the church's terms, instead of doing what I saw Jesus doing, which was going out and meeting people on their terms?Could you say that again, you said to what a church shouldn't be doing too.So a church church is so focused so much on doing ministry to a community in a community or for a community, that the moment we use those words, right, it's all about what it's about me and what I want to do to give, it's not about the other person. This is about with that, that it's what we get to do together. Right. That here's the principle behind it. Thanksgiving and Christmas, right? Your families you might be thinking, well, this Thanksgiving, Who should we who should we go serve? Sure.Or what nonprofit should we go serve with as a family? Right? Many families in America do this. That's a good question to start with, who are we going to serve? It's not the best question to start with. Because and here's why. That's an addition question. We are going to go serve them. That's one plus one. The better question is, who am I going to serve with?Say that again? Who am I going to serve with.With because, because if I want to if I want to make a difference in someone's life, then I need to be inviting you because now I get this relationship and my desire to do good begins to rub off on you. You come with me, and we together, go serve and something ignites in your heart. And now you're changed. And then you're like, you know, that just felt good. That was right. I want to live a more meaningful life, more purposeful life. We all want to do that. And so what do you turn around and do you go find another friend and you're like hey, you need to come do this with me. And so the power of the power of generosity is not found in what we do. It's found in who we do it with. It's about the relationship.You lead by example. Yes. You lead by example. You're not telling people to go do things. You say, follow me. I'm going to show you we're going to do this together, and we're going to make each other better.What he, what he's saying is not even just a theory, and I didn't get a chance to tell you this yesterday. So Ken had to leave the procedure facility yesterday earlier than I did because he had a he had an interview, and I stayed a little bit longer. We have a new center director, his name's Chris. So big shout out here to Chris. I told him while we were coming down here for the weekend, he thought it was it was an incredible opportunity. I said, Well, we'll have another Generosity Feeds event in Dallas. You may want to see it, the rest of the endo center would like to come be a part of it. He immediately said, what a great team building exercise for all of us to go down and give back to the community I mean, it bled from you encouraging us to meet your team. I just happened to mention it without any prompting from you. And now...Because it was just lift. Yeah, I think the center's gonna have next timeThat's a great idea a company like Digestive Health Associates of Texas and AMSURG these companies that we're affiliated with. Yep. We've got KBS doing it now we can just keep working our way up to the bigger and bigger companies that we have access to.Yeah.To help out.That's right that's it's pretty powerful message to to be able to go and serve with versus you're just going to go and serve.Yeah, well even take it take it to the business level now. Sure. Think about what's happened in business over the last number of years. We had Tom's come up with what the one for one model right. And it's it's all about a transaction you buy this we'll give this and that's as far as it ever goes with the customer. And then you have the companies that as you just said, this is a great team building opportunity. Let's bring our employees in Salesforce rocks it out with empowering their employees to go serve in the local community and the things that they're passionate about. But where's the where's the model? Where now as a company, you can invite your customers to come serve with you. And you're not just there, they already love your product right there. They're buying from you because they love your product. But what if you're inviting them now into your value system? And you build a relationship with them around your value system of giving back of doing good as a company becoming a force for good. The moment you do that, you turn customers into raving fans of your brand. Sure. That's the power of this. It's the power of with.Yeah. The power of with.And the interesting thing about that is that it cannot be faked. No, no. You, you either live it you say look, we're gonna we would love our customers. I would love everybody who's ever bought Atrantil to be part of something like this. But I want you to do it because you just want to do it. I don't want to do it for that you're not going to gain anything other than you're going to be part of a community you're going to serve, you're going to find purpose, where we want to be one of those companies that actually helps with something like that. You can't fake it.No, but you're inspiring something in people that's beyond a product. Definitely.We were talking earlier that there was a study when you stole the car earlier. We're...a study came out that millennials prefer to purchase from a company that they feel is doing good for the for their community for the world, whatever, because it's a very jaded society now we realize that there's just a lot of for profit things we're going to get into this because a nonprofit for profit the only way you're going to be successful is actually making a profit one way or the other. Was it Hollis or somebody else at Baby Bathwater that one time was talking about the best way for someone to have a good good experience with you and may I can't remember if it was Hollis or not but they essentially said your customers are always looking for the community net positive. Now I can't remember exactly who wasn't said that at the last meeting but they were talking about if I make this purchase then I know I'm getting this product. But what if I'm supporting a company that's also either helping the environment or helping my fellow man they're looking for the net positive with their interaction with the company because if I buy a pencil over here from let's say a name of a store but it's all about the transaction well it's it's only as cold as the money went here and I got...walked away with a pencil but maybe if I spent I don't know two or three cents more over here and they encouraged me to do one more thing in my community that brought somebody else in or made a piece of plastic.Man, I love where you're going with this it never even occurred to me that part of our follow up post purchase email should be something charitable like this. Yes, we should sit there and say not not now that you purchase this get on cuz you know it's business. It's post purchase email hope you enjoyed it we want to turn you into that promoter.You want to subscribe?Yeah do you want but but everybody's doing that. I want to do this and we're going to do this with KBMD and KBS yeah say thank you for purchasing this hey we teamed up with Ron Klabunde who has opened this thing if you are so inclined go look at it one time one email no more follow up though if then funnels this. No, just check it out. I like it you should check it out.So this concept of wanting to do things with lead you to basically change the way that you handled your approach to being a pastor. Correct. And then so when it when are you getting to the point where Replenish Foundation and Generosity Feeds and the other companies that are enveloped within begin to form on the horizon? How did that all come about?So I'll bring us back to the beginning. Okay. My wife and I were living in northern Virginia and this is pertinent to the story and that we were living in the wealthiest county in America. Okay.OkayIs this outside of DC? This is outside of Washington DC, okay. And so we wanted we we realized that people in Washington DC wanted to serve. They wanted to teach even their children the values of generosity and service, and all comes back to this. No one wants their kids growing up being an asshole. No one. And so we figured, but here's the problem. The problem is, it takes time to find a good nonprofit. It's even harder to find a good nonprofit that will let children serve because of insurance liabilities. So that's a huge thing. Never thought about that.Barrier entry point for families serving together. So what we did is we decided, well, let's create something that has a low entry level. Let's partner with the local school because the local school already has more influence than any other organization in the community. Sure. So This school is promoting it, people are going to come. So now I don't have any marketing overhead. Yay. And so then we go that we went to local businesses and we said listen, the local school we're doing this event with them. And in the wealthiest county in America catch this. There were 12,500 children struggling with hunger, the wealthiest county in America. 12,500 children struggling but the hunger back in the day. So we looked at this and we went, business leaders listen, why don't you come with us on this but also bring your employees with you as a team building opportunity. Let's just do this as a community wide and collaborative. It's a school it's the businesses, nonprofit sector, a church here or there.Can I slow you down?Please. Because I love and we've we've talked about this. I love how people end up where they get there. And clearly you saw the need.Right.I want to know even before that when you're sitting with your wife and you guys had the AHA moment you went, hey, maybe we should consider doing something like this. Because it makes total sense that you know that all these kids need to eat. It's it's those, it's those moments that build that can change the trajectory of a life.And did mine. Absolutely. We were we were, we were innovating ways to create easy entry levels for people to serve. So we tried a number of things before we got to Generosity Feeds. And we were sending kids we were doing food collection before and sending kids that who weren't going to eat over the weekend. We were sending them home with 20 pound backpacks of food. Now imagine imagine a six year old trying to get a 20 pound backpack it doesn't work right so we made some horrible mistakes in the journey, horrible mistakes. And eventually we innovated to this to this idea and and we mobilize 600 people. Event one. Wow. Wow. 600 people showed up to create 40,000 meals in less than two hours.You and your wife plan this. Yes.That is so cool. The logistics of that is so cool.Just the supply alone. Yeah.To have that. Yeah. That's pretty incredible.Now you see the community now is coming around this idea because it's an easy entry point who can't show up for two hours at the local high school to help create food for kids in that school and that school district.Yeah.Who would go hungry otherwise on the weekend?Now your experience in the church did did you kind of already know or at least somewhat predict that because it going through the Generosity Feeds event, and just like Kim described it, it was lots of instant team building with the people that were there. Yes.Did you kind of already know looking for your range in this? Yes. And I know there's there's wisdom in there yea.There's wisdom that I gleaned sure the years and there's there's a reason that every packaging station which you were both at is between 12 to 15 people There's a reason for that because we're seeking to create community. You can't create community with 600 people in one room. But if I take 600 people and I break them down into teams of 12 to 15 they're going to naturally build relationships with each other and that's what I want. I want everyone leaving with a new friend that shares the value of generosity and service.And the other thing which I thought was really cool at least when we did it was this fun competition. Yes. Yes.They're like yeah, this tables crushing it here I'm like, Come on guys, we're not gonna let them win, we have to do this. It's it's it's the human nature. That's right.Everybody was really excited as each one we would pack the boxes I can't remember how many food packs went into each box but regard...25 Okay, so you get to 25 and then basically your your tables excited because we'll we've we've sealed another one. But of course it's it's a victory for the kiddos who are gonna end up getting it in the end.So as a gastroenterologist the other thing that I was really pleased with...Yes.You guys chose a sustainable food source you had a good protein fat carbohydrate ratio. So you're not like putting Fritos in a bag and saying go home. No! Um. Here's where that came from. Um, in our family we eat as all natural and holistic and organic as we can. Nice. And part of that is my wife has autoimmune issues. I don't I don't think I've shared that before. And so she's also gluten intolerant and thyroid issues and before I give the whole medical thing that's going on with her, right? Well, here's what my wife said to me early on. She said there is no way that we are feeding millions of children in America what we're not willing to feed are own children.Good for her. So cool. That is so cool.That's the standard. And so everything we did was go out and find the healthiest we created the product but create the healthiest product we could that was lightweight. Sure. That could that a six year old kid carry home you know? Yeah, that was lightweight that could be created by the masses that could be a mobile manufacturing plant that would create community bring all the aspects of community together and could be a dance party when we wanted it to be.That's an absolute brilliant idea. Yeah, I mean, talk about a win win win. You around very clearly are not only a very generous person, very altruistic person, but pretty damn smart. Yeah. Because that is cool. You're a good businessman.Yeah. You could take you could take the letters, PDS sense PDGs already been taken.Yeah, yeah.That's right.Well, it was also it's not just infectious for the the event that we went to in Dallas We're in coronavirus season, we don't use the word infectious. Oh, sorry. Let me let me shed some light no shedding disease. No but I think two weeks before we did our event Lavich and Hollis had participate in the one was in Colorado and a very similar experience so y'all are obviously replicating all of the good parts building upon and improving. Absolutely.I'm looking forward to the to the next event we'll obviously be there but I don't want to steal the thunder we'll get to that in a moment to Generosity Feeds how people can look it up but so now you've you've gotten to the point of my wife and I have decided that we want to do something different like she's thrown down a great edict: we want to feed kids the same things that we would eat your piece it together. The first event had 600 volunteers you had 40,000 meals made. Now what?Within two weeks, I started getting phone calls from community leaders around the country going we heard what you're doing in northern Virginia. We need your help, will you come? Wow. And so theysame state?I mean, oh, no. Across the country, were calling meOh, across the country. Sorry. They were...How did they find out about it?I'm well networked. Okay, so because of just because of my background I used to...You're an Instagram model.You just got my mouth to close!So not that kind of networking, okay.No, um I used to and now I'm back at doing keynotes around the countries I teach leadership development around the country and so because of my earlier years of doing keynotes I'm just I'm well networked into the business sector and into the even into the kind of the faith sector of our culture. So people know...people are watching what I'm doing. They they saw, they knew and so within one year of that event, we were coast to coast.Holy. That's great.And that was the ah-ha moment-going back to your previous question. When was that kind of that that wake up moment? Yeah. When we were When we did our first event in Eugene, Oregon, as far as you can get away from DC. And it flew with all the same outcomes as we had in Washington, DC, my wife and I looked at each other and went, holy shit. We just started a national nonprofit that can go to any community in America. Yeah. And then it was just a matter of leading that to growth. Sure.Because growth doesn't just happen, you have to invest in grwoth, and so we began investing in the growth of the company. The other moment that was really big for us, is obviously it takes capital. It doesn't matter what we're starting in life, for profit, for purpose, nonprofit, it takes capital. I remember walking in my living room. And I looked at my wife and I said, listen, I need to write a $15,000 check to the foundation, so that this thing has a chance at living. Can I write the check? And I said, by the way, I think I'll have it I think we can pay ourselves back in eight weeks again. Keep in mind, I was a pastor. I was getting paid almost nothing. So 15,000 for me, you're going to know in a moment how close that was to my end. Wow. She says, yes. 10 weeks later, I walk back in the living room and I go, honey, I haven't been able to pay us back on that $15,000. I need to write the last $15,000 we have to our name. Can I do it? And my wife goes, "write the check."Holy cow. So just to clarify. Nonprofit, you took all your savings.Dumped it. Dumped it in there. Yeah. With the mission of saying we know we're onto something. Yes. But we're losing money right now. Yes. That's guts.Well, it was. Holy cow.It was this vision. It was the it this is a painful point to to be honest with you is that I had the we had the vision for feeding millions of kids who across America struggling with hunger but I was writing the last check not knowing if I'd feed my own. Oh.Goodness gracious. Oh my goodness. That's the level of commitment.That's the line.Dude. That is coolest thing I think I've ever heard. Yeah.I'm willing to take food out of my kids' mouths knowing that if I do this right, I can feed millions. Yes.And your kids did you sit and tell them that?Oh, they know all this. They're in the game with us.That's so cool. So cool. They knew. I know that you and I have a son, sons that are the same age. So my my youngest is 16 and I think yours is 1616, yeah.And then how many other kiddos you got?18 year old girl.Oh, that's what I have also.And a 15 year old girl.Okay, nice. I've got 18 year old son 16 year old son. You are 15...15 and 13. A 15 year old boy and a 13 year old girl.Nice. They they eat a lot. Both of them. If I sat with them and said I'm not gonna feed you for a week because I'm going to try and feed a million kids...actually I take this back, actually my kids, both Lucas and Carla are amazing kids, they will probably look at me and be like, you need to feed a million kids. Sure. We'll go forage. There's and that's that's, that says a ton about you that you went out on that kind of limb. And man, I'm so glad that you did. Because we saw the effect. Right.That you're you're doing and we only saw it on the local level. You see it all these other places we're going to, we're going to explode it tonight at this Party on Purpose. Gonna be amazing tonight.So how long ago was Eugene, Oregon's first event?That was eight and a half years ago. Wow.So now you hit Eugene, Oregon, you say to your wife, we are definitely in something that we can replicate in city to city. Yes. You're going to take this nonprofit worldwide. It's going to grow we talked about you need capital.Right. Where does Replenish Foundation Generosity Feeds began to take shape?So, we had some very wise councillors, advisors on the front end. So when we were even looking at this first event with 600 people, they said you need to start a nonprofit that is a um umbrella organization so that you can create an ecosystem of nonprofits underneath it. Because I don't want to lead six initiatives that all have their own 501C3, that's six different boards. It's too much management. It's not efficient. So far better off creating one nonprofit that can house various initiatives. So Generosity Feeds is a DBA of the Replenish Foundation. And that allows us now to be creating additional initiatives that all play off of each other.Sure.And are now working collectively to establish generosity as the new gold standard in America. That's what we're after. I know that Generosity Feeds is one of your biggest DBAs under the Replenish Foundation. What what DBAs do you have?Yea, the other one is Generosity Serves. So as of today, we have 64,000 volunteers across America. Remarkable number. Here's what's happening at events now. Oh, and we also partner with other nonprofits. Oh. So, so when we go into a community and all these meals are made, we don't do distribution. We bring in other nonprofits, we promote them at our event. Nice. And then we give them the food. So here's what's happening. These nonprofits are now coming to us going, you got 400 people from our community to show up at your event and we can't get 40. Okay. Would you be willing to mobilize your local volunteers to serve with our organization? Well, of course, I am.Sure This is about doing good. This is about becoming a force for good. This isn't about competition in the nonprofit sector. This is about helping these other nonprofits soar.Right.So Generosity Serves is a platform now where with our nonprofit partners across the country we can go into our database and begin to mobilize these people to serve with these other nonprofits in the rhythm that works for their family. Oh, wow. You haven't...you haven't you have built an army of generous people.Yes. That's where we're that's why we're seeing that we're seeking to change culture. Because we know if we can change the dial of generosity in America, even just three notches, three degrees from our present trajectory. Together, we can begin to solve every social issue that exists. I believe the timing is perfect. Also, I think I think the pendulum is swinging back away from that social media obsession and people are going I am done. I am unplugging. I want to be with somebody I want to talk I want and I think it's an incredible timing. I think that people are seeking this which is why they, you've been able to do this. Well, you've been able to do it because you're very organized and you did it the proper way. And you're very charismatic and there's a lot of reasons why your particular thing, but that's the platform that other people can go with. You know, we're doing KBMD is sponsoring Linda's Nebraska ataxia for the for the fourth year in a row. And I was just thinking the whole time when you said we team up with other nonprofits, she does, she is my med school roommate, been friends with her forever and she developed a type of ataxia. And meaning that she, it's, it's, it's like Lou Gehrig's disease, but she has the resources and she found a physical therapist that analyzed her and was able to put a vest on her with weights. And it actually allows her to walk without the vest. She can't walk. Oh my goodness. Yeah, so then so she decided on her own dime to do a Nebraska Ataxia foundation and all they do is buy them and given to people and there's just video of video of people in wheelchairs and they show up and give them a vest because that technology exists. Yeah, it's like this. There's kids not eating on the weekend. You can feed them and you can eat them good food and they're gonna they're gonna become great members of society. It's just that easy. It isn't like you're going and given some weird obscure drug. It's like oh my gosh and so like I'm just we need to get you and Linda hooked up with that or she needs that you have any events in Omaha Nebraska?Not right now. We'll set that on the through her but she's got a big network and we can we can do that.That's right. We did. I don't know what podcast that was but he came on our podcast and he taught Eric and I about toxic charity, how you can cause more damage, trying to do good by throwing...You know, it's so cool as we've had a handful of different charitable folks drop in on the gut check project and one of them that always comes to mind right off the top is another BBW guy and that's Robo Hendrickson with a I mean, he truly is...in but the way that he describes the passion behind why he does what he does transforming communities is very similar to what you're talking about. But even more to the point the way that it's not what you would consider what Robo termed was toxic charity.Throwing money...the fact that you y'all have yet another subsidiary, just simply called Generosity Serves shows that you're, you're enabling a community to feel comfortable and more community by serving together find and you even said it yourself finding ways to make it fit your schedule. And you're doing it without competition between people who are trying to do well, it's like, let's lift each other together. In my own small town. I told this to Ken we there's a man by the name of Ricky and he works through a church but he invites the entire community at least one Saturday a month to simply come and staff tables where we hand out food. That's all that we do. A lot of the different food producers in the North Texas, they donate it, they know there's going to be a big line. People come from all over. But regardless, they get shopping carts. They come out there in the parking lot. We load them up, and then they've got plenty of food for a couple of weeks. It's great. And it's giving and it's things like what you're talking about all we've ever needed as volunteers to help make it happen.So, side note, but this is a shout out and mad props to every single parent out there. Dad or mom Loy and Lucas spent two weeks in Mexico touring doing tennis. I had to try and figure out what to do with my daughter. Like pick her up from school, get her to her events, cook dinner for her. I want to say it was the two most stressful weeks I've had in my entire life because I'm trying to work. Now. I'm the boss. I started thinking, Wait a minute, I'm the boss and I do okay, financially. What happens and I started looking around my office I'm like, I have a lot of single moms working for me. Oh, yeah. Oh my gosh, I have a lot of single moms that are going to get fired when they show up late again. And there's, and they're they and I just I had this. Am I that big of a jerk that I have not until I lived it...Yeah. That's frickin hard. Yeah. And then when you don't have enough money to give your kid food on the weekend, the only food they're eating is at school. So then it's insult to injury where you're you're trying your best. Yes, they are. You want to give your kid food. And then something like this, where they just come home with a backpack and the food's already there. No questions asked. Nothing being said and it's healthy.You know what makes that story even better, is when that kid was at that school event, help create the meal and three weeks later, they open their backpack and it's sitting there and they kept their dignity because they helped make it Oh, yeah. Take it to the next level.Yeah, that's cool. Then that's that's the epitome of not a toxic charity. Because what Robo talked about is it doesn't do me any good to go to a community because just like you he's serving with them. He's teaching them how to take care of their animals, go get an education, give back to the people learn how to grow the food mill, it's very much the same thing you've removed the stigma of someone just gave me this to I created this for me and for some other people who are in similar situations. That is a pretty incredible full circle, give back. I didn't even think about that to the people that we were building these.That's where that's where I said, you very likely had no idea you're standing next to a single mom. You'd have no idea because the moment we unite ourselves around shared values, nothing else matters. You're right. Your wealth doesn't matter when you're united around shared value.This is...we do this, Eric puts my patients to sleep. I stick a camera in people's butts, the one thing that we see over and you may be a super rich guy, you may be this buff person, you may be old. We all have the same inner workings. We're all the same. That's what we totally forget. We're all the same. And I see that because I stick cameras and I'm like, your stomach looks like it looks like his stomach. We're all the same. That's right. And when we sit there and realize that if my kid was hungry, thank God, they have never had to experience that. But if we had something that I could, I mean, to be able to go and be a participant say, honey, we're going to go and we're going to pack some food and you're gonna have food for this week, but we're going to earn it. That's so cool. Non toxic charity.That's right. So we started off in northern Virginia. Yes. And then we've we've gotten to the point now where Replenish Foundation functions is a large company with a handful of charitable subsidiaries. Yes. Now today, you're in 29 different states with events correct? That's correct. So what what is Generosity Feeds is doing now? How can people that are tuning into Gut Check Project figure out where they fit in to learn how they can begin to serve with? Yes. In, in and around their communities with their neighbors at? What What can people do?So let me hit the business side of this first. Sure. So we work we work with over 600 businesses across the country. And you it's very possible that your that our listeners today have heard of something called corporate social responsibility.Corporate social responsibility.It's called CSR. And this is often used by the larger companies. Now, here's the problem with CSR. It's this. Its responsibility. No one wants to do a responsibility, something responsibility is something you have to do. Right. And yet these larger companies, most companies are looking for CSR. What's our corporate social responsibility going to be? No, we're throwing Corporate Social Responsibility out the window and we're saying listen, don't do a CSR. Do CSO, corporate social opportunity. Let us help you as a business, create a philanthropic strategy that engages your product, summit a piece of your profit, whatever you want your employees and your customers, and that customer pieces a huge piece. And so one of the things that we're doing now with companies is helping them develop their their CSO, corporate social opportunity, because when a company does it right, it's going to accelerate their business. I was talking with a very large business owner in Salt Lake City this last week, and they just dumped a lot of money into a nonprofit initiative. And I said, you know, you're about to open 25 restaurants around the country. And you're going to drop about a half a million dollars on every one. I'm sorry. $500 million on every restaurant. to open it said I would imagine what...500 million?500 million is what typically it takes to open these larger scale restaurants okay? Holy cow. So 500 million. When you when you open a restaurant, are you going into that with a strategy and a plan? Yeah, well, of course they are. Anyone would. I said, over the next 10 years, you're probably going to invest 200 to $300,000 in philanthropy. Do you have a strategy for that? And she's like, oh, I get your point. Why in the world would you take $200,000 of your profit and invested in, in nonprofits without a strategy? Right.Like, let me help you design a strategy with your marketing team that's wrapped with your values, so that so that you're doing your philanthropy with a with a purpose. So you can see the outcomes in a way that actually accelerates your business.I love this because what I'm hearing is that charity and giving back is not checking a box.No, this is this is about nonprofits. Yeah.And for-profits working together. And here's the here's the statement, not it. The linchpin is this, for profits that have the heart of a nonprofit, need to find great nonprofits that have the mind of a business. Say that one more time.Okay for profits, businesses, businesses that have the the heart of a nonprofit...Love that. Need to find great nonprofits who have the mind of a business.And you're allowing this so I'm like the fact that you said that this is a corporate social opportunity. You are figuring out how to do it well. You can come to a company like KBS and say you are leaving your customers in a position where they don't know that they can give back. And we all win.Yes. And I can coach you through I can guide...and here's the beauty of this, this isn't about the foundation. Because at the end of the day, I want your company doing what you're passionate about. Not what I'm passionate about, this is about your value system. And so if these companies choose to work with us, that's great. I mean, that's going to help accelerate what we're doing. That's not the point to this. The point is, if you're aligning your profits and your values and your employees and your customers with a great nonprofit that aligns with all of that, then guess what? You're doing good. You're becoming a force for good and that's all I want. That's all I want. Yeah. And so that's the end game. Like, why because we're seeking to establish generosity as the new gold standard. That's not about me. That's about you.You wrote your last $15,000 check, told your kids we're out of money. And you went from there to I'm now going to teach large corporations how to do it better. And it all revolves around generosity and you lead by example that day when you wrote that check.Yes.So cool. That is so so cool. I'm excited. We are leaving we are completely because we now we know everybody at KBS we're there. We all do charitable things, your donate money I do the thing that you're saying, which is you know, I, whatever, you know, I try to donate, like, even like Linda's foundation and stuff like that every year I sponsor, I'm not taking advantage of the fact that I need to spread that message because all it does is help everyone get in their lane and oh, this is where I need to drive. That's that's basically what you're telling people to doIt's the power of with.Yes, power of with.Now, that's a pretty powerful message all the way around. It just seems like that lots of corporate responsibility did turn into the checking of a box. We should be doing this. So let's be sure that we do it. And Carol, you're over there. Did we do that thing? Did we send the check did but there's there's no personality behind that there's no touch in there, you're really not seeing it.Well let's take it one step further as a pastor tithing. I grew up Catholic, right 10% Where does it go? Who cares? I don't know. I'm just giving it. It's right. Right. It's what they said we had to do.That's the world I was in too.Now, and it...suddenly just enters a world of obligation. What what was probably born as a as a good purpose. It's lost. Its lost touch. It's lost feel. There's no texture to it. It's just this this, this money is spoken for, and it's gone. So now I'm super intrigued as a business owner. I come to you, Ron. And I say I have a I have a business. We're growing. I want to get my company in this corporate social opportunity. What would be the first thing that you would do? What would what would you do with me?So the first thing I'm going to do is I'm going to I'm going to send you an assessment. I'm going to have you assess your own company as to where you're at. And that's going to do two things. Number one, that's going to help you understand wait a minute, we're not all bad. That's the first thing it's gonna do.I talked to I talked to Tim and Patrick about this that like we're doing the whole we've all read the book Traction. Yes. And so you know, you do like that, you know, you start that you start thinking everybody's bad. You're like, this is your this is your score. Eric, you're a two this week. You are a two.No, so you're gonna get some good news, right? Yeah, but you're also going to evaluate where you want to be when it comes to CSO corporate social opportunity. And then I'm going to walk you through a process of blueprint of helping you close that gap. It's that simple, and in a company your size. Four hours, you will walk away with a blueprint of going, oh my God, is it really that easy? And it is. And so if this is not rocket science, I don't need to consult your company for three months. Let's just sit down, I'll put you through the assessment. We're going to walk you them through our blueprint that aligns your social, your social good with your value system, your product and some of your profit, and boom, you walk out the door going, oh my god, here's who we can partner with. and here's how we can tie our business and our customers into it and everyone wins.We have when we launched our product, we know consistently because our research when we did the clinical trials, we know that four out of five people are going to get better, like really get better. Sure. And we when we launched we either had one star on Amazon or we had five which is not a placebo. Either we worked or we didn't. Yes. And fortunately we are four stars and close to 1000 reviews. Every single one of those people that we helped, we can say if we made you feel better, I'm going to ask a favor of you now. And then we do your process. Yes. Because you have somebody that Yeah, I do feel better. You changed my life I want you to pay it forward and be with and we can make a difference and grow this network. That's so cool. Corporate Social opportunity. Did you coin that term? Yes. That's awesome. Only because CSO doesn't it doesn't work. It's it again. It's a check a box. It's it's not the heart.Right.And we're we're seeking to pull out of people, the values that are in them, the values in there. It's just letting them come to the surface and begin living.Isn't that so interesting? Because you can see how many people want to have that pulled out of them. Because we think that everybody's own superficial stuff, but the reality is, when we went and when we did Generosity Feeds, that was an enthusiastic, it's not like...From the moment we walked in.Oh my gosh, everybody the energy was amazing. Yeah, people want to get off of this superficial thing. They want to be part of something. And if they know that they can, it just comes to them. I mean, I'm the same way. I mean, I was so excited. I only found out about it because Eric said, hey, one of our Baby Bathwater people does this. I'm like, Okay, what are we doing? I was on call that weekend and everything. And I was like, Okay, I had no idea. Yeah, loved it had fun. And I'm somebody that is perfectly willing to give back and try and help out wherever but it doesn't. Since it's not being fed to me. I'm busy. I forget. Now, if we can sit there and develop some sort of process where and we can get other companies, like some of the other companies that we work with,You know, it's kind of interesting is it KBMD Health, but also just in the direct patient contact that we have. We talk about diet, we talk about exercise, we talk about different things that people do to improve their own health. And since I was a kid, I've heard that many times just simply giving of yourself will reward you even more than than whatever, but you hear it. You don't always get a blueprint on how do I effectively give back and it sounds to me like probably what you're really doing is, it may sound elementary, but you're just helping people rediscover the new way to find their purpose and then suddenly you begin to feel better. Suddenly depression issues aren't nearly as bad as they used to be. Because if you think about a gym, do you think gyms existed back in the 1800s? Could you imagine in the 1800s telling someone, we're going to have this building, and there's going to be metal bars, and we're going to put weight on them. And we're going to lift them, and we're going to put things over our heads. And we're going to do some stuff like this, and we're going to do some stuff like this. You're gonna look great, you're gonna feel good, and some cowboy would have shot you between the eyes and go that's the dumbest thing I've ever heard of. Have you ever heard that whole Jim Gaffigan set where he's just like, what in the world? How do people develop a Stairmaster? Hey, I got an idea. You know, people love walking up stairs. Let's make one that's never ending.But, but people, they they've gone to do that because that level of exercise for whatever it is, is keeping them in shape and helping them feel better. It just seems like what you you're doing is reintroducing people back to what they've become this...they became disconnected from your core. It's why people do yoga. It's why people do meditation it's to return to who they are. This is not that different.I have an idea for you. I think you should make the food much heavier like 20 pounds. Put it on the kids Yeah, give him a little workout. And then let 'em do squats.Do Memorial Day Murph For Memorial Day you go to Generosity Feeds get your 20 pound pack. Go do some air squats.Oh my goodness.That That is so cool. I'm just I'm I'm loving the idea that we could sit there and send a post purchase email sequence that just says hey, it's time to give back time to give back if you got better great if you didn't get your money back because we have 100% money back guarantee. Yeah, you didn't get better. Here's your money back if you got better now you need to pay for it. But not you go give back. Give back with us.With us. relationship. Everything's relationship.Let us know how you're giving back also, I mean, justWhatever it takes. But it's not you know, I mean, what I like what you're doing is you go, I'm a company your size, I need four hours, I've got the process, you very clearly are a very detail oriented person. You think through all these things, you've got 64,000 soldiers, that got your back right now. That's what we would need. I mean I want you to come to me and be like, here's what you're gonna do. That's what I love about traction. It's and you can do this, this, this and this. Now for your charity, you're going to do this, this, this and this, not write one check every Sunday.Yeah. And walk or interplays with what you are doing from the book Traction. Because again, when we talk about our, our body and our health, it we're holistic beings, everything in our place, right? Same thing in it, same thing in business. What you do in the philanthropic side of your business needs to completely interplay with what you do in the profit side of your business. Let them intertwined they're not two different silos, and that's what we're bringing together.Yeah, man I love what you're doing I absolutely love what you're doing and I just I like hearing the story how I built this because people look at this they're like oh yeah he's charismatic guy, he's a coach whatever know you wrote a check with the last money in your bank and you went...It hurts.Yeah, just just to reiterate, in case you're joining us late in the podcast and you're just joining in because somebody else...If you're joining us late just rewind and start over cuz it's all really good.Generosity Feeds does not handout, cheap meals and sweet tarts. This is legitimate food for kiddos that don't have an opportunity to eat and don't have an opportunity to get a good meal on the weekends and you've stepped in and you've allowed people into your vision to serve in a serving with you, which I think is awesome.You know what I really like also having kids our age, Eric made it a point to make sure that it was a family involvement. Gage brought his girlfriend. Yeah, it was it was we're going to do this. I'm going to lead by example. I'm gonna put the hairnet on. I'm gonna put the gloves on. Yeah, you're gonna see your dad do it first. And then follow my lead. So it's the same thing you lead by example. You teach others to do that they teach others to do that now we're all with it. And the car ride home was was filled with smiles. It was rainy that day. Yeah. It was rained hard that day. But I mean, everybody was like, man, it felt great.Yeah. And then is the conversations as a parent, reinforcing the experience. Sure.That's the power. Definitely no curriculum needed. How do people find you Ron? How do people help out?Easy. Email me at ron@replenishfoundation.org that easy, different ways to help out. Look for an event in your area. That's one If we're not there yet, that's fine. How do they find that? Is that on Generosity Feeds?Go to generosityfeeds.org.org, o.r.g.Yep, generosityfeeds.org go to locations, you'll see what's coming in the next usually four months. And in we're already booking 18 months from now. Whoa, it's crazy. So that's but that leads to part two. If you're if you lead a business that is wanting to do good, or you're a community leader, have it, call us we'll come to an event with you, like will coach you on how to mobilize your entire community and work with you and support you in this because it's all about the width. So break. Let's do this in your community. Let's do this together. So that's the other pieces go to generosityfeeds.org and just contact us and we'll, we'll help get this going in your community.Do you hear that Linda? Nebraska Ataxia, hit him up. Omaha is gonna be the next place to do a Generosity Feeds spot. And then we're going to team up two charities that I support.29 states covered right now, which means there's 21 left just in the US alone. So knowing that if I were a corporate person who wanted to be a corporate partner, and I know that we said that you don't just want to write a check, but you do need supplies.We do well, and we have national level funders, that are helping advance the mission. So you have we have local people who support the local events. And then we have the national partners, which you guys are, that are helping mobilize us into new communities across America that are helping us empower 64,000 volunteers, because the idea needs to be needs to spread.I just thought about something here. So if I'm a I'm not a I don't know how to say this in the right way. But if I'm a a family, yes, that is a tight on budget, right. And it's just easier to spend $8 at McDonald's to feed the family, is there I just don't know how to say this. But I would almost like to tell my patients for instance. Because I hear this from my patients all the time. It's very hard for me to shop at Whole Foods or whatever, or it's just easier that I can get McDonalds and you know, and I try and get them off of that. Is there a price point? Can anybody be part of this? Can anybody use eat it? I mean, basically, I would I would tell my I would tell my patients, go to Generosity Feeds, pack your own bag, make sure you eat this on the weekends and don't eat that crap that you find cheap.At our events when people come to at the end of all of our events. Here's what we say if you are here today, and you need food, just come see us privately. Because you're going to walk away with food. So it's that simple. Yes. Is the food already designated to the nonprofits that are going to distribute it? Yes. That doesn't matter. Someone when someone comes to an event needs food. Just come talk to one of our team members. We're going to hand you the food that you just created. Walk away with it.So DHAT my company. We need to do something with this also as a gastroenterology as the gastroenterologists for all ages that are the premier gastroenterology group in the country, we need to lead by example, we need to do stuff like this. Definitely. I think everybody be on board too. This is another one of those things where you just delivering laser focus to a lot of people who want to serve, they just don't know how to do it, or how to do it together.Well, sometimes it's the conventions, like Mod Pizza, as you said, is a title partner with us-national partner with us. So they do a leadership summit with all their general managers every year, guess what we do? We go in and catch this. This year they're creating 50,000 meals, they'll do it in less than one hour with 2,000 people. Like so. So we can come into these conferences and conventions and and we do this. We're working with Microsoft right now. Like, the coolest thing ever. Who are they? Yeah, I don't know. I think an up and coming company to buy some stock. So again, it's In those are private events where it's just that Corporation but it's like you so cool. You got this group around the country, the doctors come together. You put them on. So many companies talk about doing good. Let's just do it will bring it to youDon't talk about doing good.Well, just and I'm sitting there thinking we've got my company, I'm just thinking how many of these single moms that work for us that probably would be relieved that they could go home with some food. Because I found myself running out of time not cooking for Carla for those two weeks and ordering food and we ate like, well, we'd like crap per our standards chair. Um, it's, it's relative, right? I mean, it's, you know, read a lot of Thai food and whatever, you know, which I like. But um, but I wasn't cooking whole food. I wasn't doing the stuff that we normally would do.No, I agree with that, and probably the epitome of a lot of the people that want to give back, who aren't always in the best position to give back happened to be those same people. I would never know who actually truly struggles, it is walking amongst us until sometimes they kind of hit a wall and they just like, for the last number of weeks, I've been dealing with this I'll look and I'll say I had no idea. But that same person, whomever that would happen to be, I'm certain would jump at the opportunity to help a neighbor or friend. And then of course they would have the opportunity to benefit and take something back to their kids. That would be kind of incredible.Wow, I want to thank you so much for coming on. Thanks, Ron. I want to thank you for you lead by example. You're certainly gonna make a difference with us. We're gonna we're going to jump on board with KBS KBMD DHAT. We're remembering we're going to have the corporate social opportunity be our new motto.Yeah. If you're only watching us on the YouTube you may have missed we are down here in Austin, Texas for what they call the Austin POP the Party on Purpose yes event where we have a handful of corporate entrepreneurs who've come down here to Austin basically to help Generosity Feeds and Replenish Foundation mobilize to more areas throughout our country feeding kiddos that just needs some good meals. So Ron, I can't thank you enough for just bringing to life an incredible vision for a lot of people who just needed it. So it's, yeah it's awesome.I appreciate it great being on with you guys this is honestly just been a lot of fun. Oh, good, good. And I'm sure it has been for everyone else too.I hope so!Well, hopefully this will kind of spread and this is a great example of leading by example living by example. Corporate social opportunity Generosity Feeds Generosity Serves everything you have said is just makes me feel like I'm kind of a bad person and I need to do more.That's probably going to do it for Episode Number 35 Ron Klabunde here from Replenish Foundation and Generosity Fees and Generosity Serves look him up everything in show notes of course, check us out, like and share Gut Check Project KBMDhealth.com. Dr. Brown, anything else?Yeah, I'm going to task everybody with a personal social opportunity. Definitely like and share this particular episode, because it goes way beyond the Gut Check Project,Send it to your boss.That's a great. Send it to your boss, find something that where you work or with your team. If you haven't been an entrepreneur, how can we begin to work together? This is your team building exercise. It costs you nothing, and it gives everything.Here we go. I'm going to I'm going to share this with Loida right now, my boss, my wife.Thank you! Tune in to Gut Check Project. We'll see you next week, don't forget we have a giveaway Dr. Brown's signature package Episode 36.Find a “Feeds” event near you https://generosityfeeds.orgOrganization Info on the Replenish Foundation https://generosityfeedsportal.org/uploads/images/prospectusreplenishfoundation_email.pdf

Stroke Prevention and Recovery: The ECS and Your Brain

Play Episode Listen Later Feb 27, 2020 39:35

Eric Rieger Alright, we're going to get down to the gut check project starting on episode 34. It's gonna be a quick one, but you're gonna love it.Ken Brown Yeah, we're gonna try and do this a little bit quicker because what I've gotten some feedback is when you guys get all sciency that sometimes it's it's cool to hear the fun stuff, but the reality is that the science gets a little geeky and it gets almost like a lecture. So I apologize to everyone out there if I've been some weird professor but so my only thing so let's do the personal stuff is your family good? Eric Rieger Family's Great! Awesome. Ken Brown My family's great also awesome. And that's up for the personal stuff. So like I said, I was called by a good friend, Tim, our good friend his father had... Eric Rieger Tim Power been on the show. Ken Brown Yeah, Tim power been on the show. His father had a stroke. And he messaged me and he said, Hey, man, my dad had a stroke, and they don't seem to be talking diet. They don't seem to talking supplements. He's in rehab. He's getting better. I'm doing my own stuff. I'm trying to fix this. But do you have any recommendations? And rather than just knee jerk and go, Oh, I'm going to go ahead and yeah, just do this and this and this. I started thinking about it. I went Holy cow, my hospital. Medical city Plano.Eric Rieger Right. Ken Brown Is a level one trauma center and is designated as a magnet hospital for stroke, acute stroke rehabilitation. Eric Rieger Okay. Ken Brown So they have a whole team that if you show up with a stroke, it's just like a heart attack. They're badass. Yeah, they show up with like this team of interventional neurologists, and they get in there and they do all this stuff. So I'm sitting there. My quick side note, I'm picking up my family from Mexico, because Luke was just playing tennis. You know, that was the the personal part of it that we didn't get into, but just assume it's tennis. Eric Rieger Assume it's basketball.Ken Brown Yeah. So I called. I called the stroke rehab unit. And I spoke with them with the nurse. The manager, nurse and she was so cool. She's like, She's like, hey, yeah, blah blah blah Yeah, we were our rates are this. This is the protocol. I'm like, what's a protocol for diet? We don't have one. What's protocol for supplements? We don't have one i'm like, Oh my goodness, let's look at this. So I called our secret weapon. And I started to get into it and it's a much bigger bite to chew off then we can do in this sort of quick episode. So this quick episode, I want to just focus on the endocannabinoid system and stroke. Because what we do with stroke victims is that we basically do everything wrong. Eric Rieger I believe it. Ken Brown In the hospital. Eric Rieger Yeah. Ken Brown And when I asked him, like, what is the typical diet? She's like low fat. Eric Rieger What's the science behind that? Ken Brown Exactly. And we know that the carbohydrates increase inflammation and this and that. I'm like, Well, what else and she's like you had traditionally everybody gets put on a Staten, which causes some brain inflammation, because we're chasing numbers on cholesterol. Anyways, keep listening, because we're going to end up doing another episode on we're going to develop a protocol that I hope everybody adapts, and the nurse was like, that would be amazing. nobody's talking like that. Because everybody has this hammer. I mean, we bring these people in, they have a stroke. And one of the most important things is sleep and what do we do just disrupt sleep, check vitals blood sugar, and all this other stuff. So basically, we focus up we focus on all this stuff. So I called a couple neurologists, and was like, Hey, man, what's the or Hey, woman? I don't want to be sexist here. I'm like, Hey, what are we doing here? What's going on with the you guys are crushing it. So basically they focus on the awesomeness science of clotbusters like tpas and blood thinners. And then they rush in with this incredible technology that is amazing. Where they get in and they do like cardiac clot, like the same thing that the cardiologists have been doing. That they end up just sort of extracting these clots and they just crazy stuff. It works, but then they don't think about anything else,. So here a gut check project. I feel like we check our egos at the door and we look and go, how can we do things a little bit better? I feel like that this conversation that we're having could be the beginning of something bigger. Sure. I feel like we're missing a ton of stuff. This is not to bash traditional medicine at all. This is just a glorious example of how medicine save lives. But unfortunately, if all you have is a hammer then everything's a nail. So we're going to go ahead and look at that today. Eric Rieger Let's do it. Ken Brown I'm gonna do one brief thing. Because we always do in in the news, we always do our personal lives in the news, mostly because it's a win for me. So I'm just whenever I find news that is pertinent to me, I'll talk about it. And I'll just kind of, like most people just sort of ignore the stuff that bothers you. Bottom line is a study just came out. Looking at coffee. Eric Rieger Oh, I love coffee. Ken Brown So February is Heart Month, right? Eric Rieger It is. Ken Brown So everyone talks about Heart Month, and we're strokes are almost parallel to heart. So the same vessels that can ruin your brain can ruin your heart. You're gonna die either way. Let's start fixing it. Eric Rieger Yeah. Ken Brown So a study came out this last Thursday. So just a few days ago, in a journal called PLOS biology that I follow, which always looks at like new and upcoming research, as it find it. As it turns out, we know that coffee is good in 2017. There was this big meta analysis that show that help with diabetes. And also helped with cardiovascular disease and different things like that. But we really never, we always thought it was the polyphenols. So these guys looked at this and they took mouse models. And what they showed is that the caffeine plays a role. Eric Rieger Nice. Ken Brown Yeah. In case you haven't guessed that I drink just tons of coffee. Eric Rieger I didn't have to guess I see it all the time. Ken Brown Alright, so anyways, they took mouse models, and what they showed is that when you drink four to five cups of coffee equivalent in caffeine, you actually improve the mitochondria in the heart cells. They even show that the mitochondria is that you know, it's the powerhouse of the cell. It's what makes you walk around. It's what drives every single cell they found a protein called p 27, which is stimulated by caffeine. And when they gave heart attacks to mice, and then they gave them coffee, the mice that got the coffee, or the caffeine equivalent, recovered quicker, knockout mice that they took away the P 27 protein or whatever, they all died of heart attacks. So quick little thing in the news, coffee good, helps diabetes helps heart disease. And now we realize that it improves mitochondria. So I got to thinking and I was like, wow, the whole mitochondria is our aging thing. I found an article where they looked at old an aging mice, the more caffeine that they took in during the day, the more that their mitochondria were younger, and it was an anti aging molecule. So polyphenols plus caffeine, it looks like.Eric Rieger it's really interesting, brief note, and maybe we should even do a show about caffeine and the systemic effects because during anesthesia school, we talked about why caffeine does what it does, and the jitters. And essentially, the way it was explained to us and shown to us is that they didn't know the exact mechanism, but they could tell that the threshold that it took for like a neuron to fire was lessened. So what it does is it lowers threshold to elicit an action potential. It would make sense that somebody who's a little bit older, basically you're taking down the barrier. And now you've got demand making the mitochondria useful. I mean, it's...Ken Brown Yeah, I like where you're going with that.Eric Rieger It's all kind of systemic, we'll get to that. That sounds like a an interesting... Ken Brown So that's just basically in the news Heart Month now we're doing this... Eric Rieger And if you think this episode's fast, wait til we do the caffeine one.Ken Brown So this is just one of those things where we're, we're trying some different stuff out but one of the biggest problems I had is I called the stroke center and they do not have a protocol. And then when I called the neurologists and and I said one thing I was like, have you guys ever thought about the endocannabinoid system, in your specialty.Eric Rieger No, they haven't.Ken Brown Not only No, it was a hard no with that BS. Eric Rieger Sure. Yeah. Ken Brown So rather than get an argument and like, we'll just do a show on it.Eric Rieger Yeah, we will. Ken Brown So this show should be titled the anti bs side of endocannabinoid system and stroke. Eric Rieger Let's do it. Ken Brown Alright. So, once again, geeky sorry, we've done two geeky shows in a row. We're gonna have to start having, you know, just playful things. We have to have a comedian on like Joe Rogan or something like that.Eric Rieger Eventually.Ken Brown Yeah. It's probably a little premature. Alright, so let's talk about the endocannabinoid system really quick. I'm gonna throw it to you, and I'm gonna let you just to describe to everybody what is the endocannabinoid system. Eric Rieger The best application that we know today that I understand is it basically functions as a great communicator, between our nervous and our immune system. So you have these two systems and basically it functions as the regulator. It's the one that prevents one from being overstimulated and driving the other one to do something that you don't want it to do.Eric Rieger 100% So the way that I describe it to my patients, our endocannabinoid system is like any other system in our body, you have a cardiovascular and neurologic. The endocannabinoid system works like a traffic cop. And what it does is it says we need more inflammation here. Whoa, you're overreacting. Why don't you just calm down right over here? So keep that in mind, because as we talked about the endocannabinoid system, now we're going to talk about how does the endocannabinoid system relate to stroke. So unfortunately, we got to talk a little bit about strokes. And I like history you like history. So, Hippocrates, the father of medicine first recognized strokes over 2400 years ago, we got 2400 years to figure out how to fix this. At that time, they called it apo Plexi, which means struck down by violence. So 2400 years and to this day stroke still kill 140,000 Americans. That's one out of every 20 deaths. Eric Rieger Wow. Ken Brown Someone in the United States has a stroke every 40 seconds. That means every four minutes someone dies. Every year more than seven Well, let's just call it 800,000 people in the United States have a stroke. About 87% of all strokes are ischemic stroke. Which means it's decrease of blood flow. And $34 billion are lost every single year due to strokes. Stroke is a leading cause of serious long term disability, stroke reduces mobility in more than half of stroke survivors. So the, if the actual death is not shocking enough. It's your health span is reduced. And you and I always talk about lifespan versus health span...be healthy. So what I'm going to talk about right here is crazy that this is not being implicated. This is not are not implicated not not being used in the traditional sense.Eric Rieger Gotcha. Eric Rieger All right. So, right now, the cool science going on is that we've got all this intervention, we got labs, we got stroke centers. We did we're, I feel like we can do a whole episode on just the diet, the supplements, everything around lifestyle on a stroke. And we're going to do that just like we're gonna do the butyrate episode coming up and just like we're going to do, every time we get into a topic, we start digging deeper, and we learn a little bit more. So today, the fact that these neurologists are saying, oh, food is Bs, well, I'm just taking on the big 600 pound gorilla. I want to say, Well, I want to know what you're not even thinking about endocannabinoids are you? And they're like, that's really bs. Now we're gonna get into it. So it is there's tons of research in the animal model of how to target so this topic of this podcast is the endocannabinoid system and strokes. Holy cow, there's tons of data on this and we're not even talking about it. I'm at a, a world class Stroke Center. Where we save more people than like anyplace else. We've been given national recognition. If if you're the CEO of who owns our house, the old colombia The HCA HCA if you're the CEO of HCA, pay attention because I can say more people for you, because as it turns out, there's lots of confusing data out there. And I took the time to go ahead and look at some of this. It's really cool. Basically, we've already reviewed the endocannabinoid system. Now in this endocannabinoid system, there's two primary receptors. We're learning that there's more for the Wil Clydens of the world that are super smart, and they understand that there's a lot more than that or the Chris Kressors and people like that. But for the general public, there's two receptors, cb one and CB two, there are the traffic cops, right? So that's what we have to realize. So as we alter the endocannabinoid system through different things, we know that the endocannabinoid system is associated with Parkinson's disease. It's associated with Alzheimer's and multiple sclerosis. The only drug approved is epidiolex for seizures. This is part of the problem. It's the confusion of what's going on? People say what does the FDA say? Well, did you know that the FDA just missed their mark to present to Congress on February 20? No? Ken Brown Yeah, they missed it. That's another news article. They did not come up with a consensus statement on CBD when they were mandated by Congress to do that, because everybody's so confused. Eric Rieger Wow, you know, I didn't know that we should look into that.Ken Brown And we know that in those studies of epidiolex, there was 86% side effects and all the things. So what I'm going to get into is the full spectrum, what we're looking at here, so stick with me here I know that I'm kind of bouncing around. What I'm trying to do is set the stage that the endocannabinoid system is intricately related to the disease known as a stroke or the event known as a stroke. So knowing that the endocannabinoid system is important in Parkinson's and in Alzheimer's, dementia and such like that, what we want to try and figure out is how is the endocannabinoid system related to similar things which is Parkinson's and dementia are inflammation in the brain. Well, the stroke is immediate inflammation. Alright, so CB one receptors. I say this only because the argument will come up will be like, well, I found some studies that showed that there were some studies looking at CB one receptors were when you had knockout mice, they did better. Other studies show that they did worse. Some said that this and that. And so I was going through all this literature going, this is silly. This is we don't really have a conclusion. So the bottom line is, think of it this way. And I will use a Will Klyden quote, it is a symphony. It is not one instrument. When you are looking at the endocannabinoid system, if you are just going to focus on one thing, which unfortunately researchers do because it's impossible to account for all the other variables, all I can say is CB one is intricately involved and it may be involved in a negative way. When it becomes a stroke. So if Your endocannabinoid system is not in tune. It can make it worse. Just like a symphony where you have the brass section which is just screwing it up. You've got the rest of the symphony playing Mozart and you've got some other people just kicking some cake. Eric Rieger An orchestra with only symbols is not very entertaining. Ken Brown No, it's not. So I bring this up because when you start trying to read it and debate it and look at it, you can be thrown curveballs. One of them is that and, but then you dig deeper. And there's all this literature on this instrument called CB two. Cb two is the other instrument, cb one, cb two are the two receptors. Now we're learning more about the endocannabinoid system, the data is much more straightforward on this. Basically, multiple rat models have shown that when you give an agonist or a CB two activator, both pre stroke and post stroke you decrease the amount of damage, so you can actually prevent what's going to happen. And then once it happens, you go, Oh, we need to stimulate that. Keep that in mind. Because to prove a point further, when CB two was blocked, the rats had tremendously more damage and they had residual effects. So just by saying the endocannabinoid system, and they're like, oh, it involves CB one, cb two, which is the top level that everybody talks about. The interplay is way more, you gotta let the body do what it wants to do. can't shut one off, you can't turn one on. You can't encourage you have to be able to let the body do what it wants to do.Eric Rieger No, definitely. And that's, that's really not that different than lots of different drugs which they thought they pulled them out of racemic mixtures. And then what racemic mixture means is you've got two different variations of the same molecule and one's active and one isn't But then they learned that sometimes if you do one and try to isolate it, you actually caused damage. Whereas before, if you had them together, you didn't have that damage. And it's played that multiple times.Ken Brown So clearly CB two receptors play a very key role. What I'm trying to prove here is that when we take these animals and we mess with these receptors, we either increase the damage or we decrease the damage. So the theory is that the endocannabinoid mediated modulation of the inflammatory process is the reason why people get better. So in other words, we always talk about inflammation. Now they're realizing that the CB two receptor mitigates the inflammatory process during an ischemic event. Eric Rieger That's pretty important. Ken Brown It's really wild. So now what actually interacts with these receptors? So if somebody's never heard these terms before, they're like, man, they're talking weird stuff. They're talking CB one, cb two, don't worry about that. Cb one, cb two are just two likeminded things that are trying to make you better. As it turns out, we can say this about every single system in the body there's going to be interactions, downplaying in the gastrointestinal system. Histamine will stimulate a cell which will produce gastrin, which will increase the acid production blah, blah, blah, we know this Eric Rieger But histamine could, the same molecule on a different receptor could cause a completely different Ken Brown 100%. So why would the endocannabinoid system not be different than every other system? Eric Rieger It's it sounds to me like it's very normal. Ken Brown You know what I keep saying? We're gonna have Endocannabinoid ologists I'm gonna be the first endocannabinologist. I'm gonna get myself a title. So somebody had to be the first black belt or something. I mean, why don't I just rushed to be like? I'm It! I'm it! Eric Rieger I'm the BBECS. Ken Brown Yeah. Alright, so there's two endocannabinoids. What I mean is you make your own CBD. And those two things there's we're learning that there's lots of them. But for the basics it's anandamide and 2ag. So knowing that you have these two endogenous meaning two endocannabinoids that stimulate CB one and CB two now we're just learning what they do. Okay. So 2ag goes up dramatically following a stroke.Eric Rieger So trying to do some damage control.Ken Brown We don't know...Eric Rieger We don't know...Ken Brown We do know that when anandamide is the soft light that is always on when you go through a stressful event 2ag turns on switch the flashlight. So the feeling is that that 2ag is the fight or flight Endocannabinoid. Eric Rieger Oh, okay. Ken Brown Yeah, so when you need it, It ramps way up. In situations where there's cell damage, it doesn't know the difference that there's cell damage possibly it's ramping up because it's like we're in fight or flight mode. We're dying here. Eric Rieger Where's the inflammation? Ken Brown Yeah, so these guys are postulating that when you block 2AG, the stroke damages less. My feeling is well, what if it's doing something someplace else? Like, what if you needed that 2ag burst? So when you have fight or flight, you need it for different things. Sure. Some people would say, oh, you're having a fighter flight. You're being chased by a saber toothed Tiger your blood pressure's up. We should give you blood pressure medicine. No, it's the right thing that should be happening right now. Yeah, I need the blood pressure to pump the blood. So we know that that to ag is your fight or flight Endocannabinoid think of it that way the flashlight Anandamide is the one that you want up, that is the Eric Rieger Parasympathetic, your rest and digest. Ken Brown It's the it's not quite the parasympathetic one, but it's the one that is your baseline that should always be filled, that anandamide tank should always be filled. 2aG. We're gonna learn more about it in the future because we haven't studied that as much. But when you have 2ag around, blood flow gets reduced. So the damage is worse. And this is really interesting because when your baseline anandamide is low, your 2 a G will overshoot. Eric Rieger Okay.Ken Brown So they work like a seesaw. So if you can get them in balance, we always talked about balance and in sync. When your anadamide is full and your 2ag is full, they never really mess with each other. In a situation where you're depleted in your endocannabinoid system, then you will have the propensity to have too much 2Ag and your anandamide is in fight or flight and your endocannabinoids will keep producing the two AJ, Eric Rieger That is very, very interesting. So in other words, what we want is to never be in a position where our our ECS is low on what it needs to function. Ken Brown 100% so anandamide we're now learning is probably the baseline Endocannabinoid that controls the day to day response that you're having. 2ag turns on when you need it to turn on. So, although the animal models show that 2ag increases significantly causes vasoconstriction and all this stuff, we're learning that okay, maybe, maybe this is my theory, the stress and the chronic disease. Listen to this one more time here, the stress and the chronic disease that led to a stroke. Meant that your anandamide was being depleted and your body was getting ready for the event. You're 2ag going up. So stress, lack of sleep, diet, all have been shown to decrease our anandamide levels, stress, lack of sleep and diet have all been shown to be linked to cardiac and stroke and every other event that we talked about Eric Rieger Time and time again. Ken Brown So when I grab a neurologist and I say, Have you ever thought about the endocannabinoid system, the religious stroke and they're like, that's BS. I'm being nice about how they said it to me. Are you kidding me? Eric Rieger Well, it's...Ken Brown we're missing this huge, giant piece.Eric Rieger It's kind of sad because the research isn't it's not one paper. This is it's ubiquitous, it grows every single day. I think people have over the last 50 years have forgotten that innovation brought us to where we are now. I mean, we used to not have TPA we used to not have kumudin and we used to not have these things I mean it those were also new introductive things for us to figure out.Ken Brown I was talking to somebody yesterday and they were like you know what's really skewed when you look back at like the the average lifespan when you when you factor out the deaths at birth people still live to like 60 and 70. Like, like, but there was so many things that killed babies Eric Rieger Oh, you mean long ago, Ken Brown Like long ago. So when I say that Hippocrates was describing strokes, and you know, 2000 years ago, whatever. But this is so fascinating because think about this, if you keep your anandamide levels optimal like adding Atrantil which blocks an enzyme that breaks down your own anandamide levels. That is something that we can look at, and I think that's part of the next episode. But when you take CBD, so our CBD product here, when you take a good quality CBD it doesn't even bind directly to CB one or CB two. We know that a full spectrum product has many cannabinoids and other molecules that bind to certain receptors. We also believe that CBD will play a role in helping the body to produce more of its own Endocannabinoids. So what I tell my patients is that if you take CBD, you're going to increase your own anandamide levels. You take CBD plus Atrantil, That's the signature package and you're going to make sure that you block the enzyme that breaks down your anandamide Eric Rieger So it lasts longer. Ken Brown So it lasts longer and the neurologists like there's no science in this. Okay? So I had to dig deeper, or our secret weapon dug deeper for me. In rat models, infusing CBD into the brains of rats significantly helped to decrease the amount of damage and help recover in stroke. Really CBD does nothing? They actually injected CBD into the brains of rats that they cause strokes. And it actually blocked the ischemic event. One to One. Crazy! Eric Rieger That's noticeable. That's a reproducible event.Ken Brown Then in another study, they showed that the blood brain barrier sealed its tight junction and decreased brain swelling post stroke when you gave them CBD, Eric Rieger Which is huge. I mean, I know it sounds really, really technical, but trust me, that's not nothing.Ken Brown Remember the whole reason that I'm even talking about this is because our friend Tim just called me and said, Hey, man, my dad's in rehab, and they're not saying anything. Well, it was shown that continued oral administration post stroke at one week, and one month reduced the volume of infarct and improved neuro behavior on autopsy. So they're taking this it showed that CBD reduced white matter injury reduced glial response, meaning that the cells did not react to it. And it increased BDNF.Eric Rieger Which is what you need for repair.Ken Brown You need that for repair. Shit! This is nuts. Yeah, we're over here saying that CBD isn't do anything where the endocannabinoid doesn't have it and I'm finding article after article and these guys are finding amazing data BDNF. If I the first thing I would do would be to the first thing I would do would be to put people we're going to come up with a whole protocol. And I'm gonna go to HCA and don't be like, everybody that has a frickin stroke needs ABCD and one of them's gonna be frickin CBD. This is ridiculous.Eric Rieger We've got some opportunity, though. And not everybody's closed, we could probably find a couple of neurologists around here in the area that are at least willing to fairly examine data and dive in. And that's what we'll have to do.Ken Brown We're gonna end up having to go into this. I mean, the fact that I called my own Stroke Center, and the nurse sheepishly said, Well, you know, they do the usual things that put them on a low fat diet, and I stopped her. Which, by the way, it's really cool, because when I called up, I was picking Lucas up and I was like, yeah, hey, it was nurse manager. And she's like, Yeah, and I said, I said, Yeah, this is, this is Dr. Brown. Do you have moment to ask couple questions. She's like, sure what patient is that? Regarding? I'm like, now I just wanna ask some questions. And she stopped. She goes the GI Doctor said, Yeah, she's like, oh, like, what do you mean uh Oh, she's like, I've seen your show. I'm a little scared what you're gonna ask. I'm like alright and so that's how we got this talk. So right now new models are looking at immediate administration of CBD and hyperthermia. So somebody out there is saying, if we make them cold and give them CBD, and it seems to be a synergistic effect Eric Rieger Wasn't that long ago, people thought that making the body cold was a bunch of Hocus Pocus crap, too, right? It really wasn't that long ago. And so now we've returned to its natural element, all we're doing is reducing body temperature. But however long ago it was, I can remember people saying, Well, you know, they're trying the cryo, and at first like, hey, maybe it works. And then suddenly, we saw lack of decrease in loss of neural function, you know, make believers.Ken Brown So I want to play devil's advocate, and we talked last time that we're going to do some sort of like contest. Here's the contest, for the listeners. All right. There is a reference when I was looking at all this stuff, one reference, there was an article on stroke in cannabis ingestion, where they said that cannabis ingestion increases the incidence of stroke. So and then I went and found the article and realized there's a lot of other factors associated with that, much like the FDA article that we did on liver failure. It's very much like that. But the FDA is using an article like that and ignoring everything that I just said. And they're using that. So what I propose is and you figured out, you're the you're the techie guy, let's do some sort of giveaway where if somebody the first person that messages us in one way or another email, Instagram, Facebook,Eric Rieger Paul we're gonna need help with that, Ken Brown yeah, snail mail, whatever, I don't know. That references the article and puts the author's names down because the author's names you'll you'll really, you'll You'll definitely find the article when you find this author's names, that I think we should give them a signature package Eric Rieger Signature package if you find the well hidden, gem about marijuana, cannabis smoking and stroke causation, right? Ken Brown Yeah. So spoiler alert. So I'm going through a whole Rick and Morty Phase I should do.Eric Rieger If you're not watching Rick and Morty, that's one way to decrease anxiety.Ken Brown All right.Eric Rieger This episode is brought to you by Rick and Morty.Ken Brown I cannot believe it's took me this long to find that show I am I come home and that's 20 minutes of just complete giggle time, just total giggle time. Alright, so lots of cool animal data. I just explained what I think shows that the endocannabinoid system is intricately related to strokes and how we can improve it and in some ways if you try and mess with it, make it worse. Eric Rieger So let's I know we did a quick episode but let's just do a quick rundown to make sure that everybody who's listening or watching can make their own crib notes. So, essentially, before and after a stroke, you can prepare your body for better recovery or prevention of the stroke itself that comes from having a healthy endocannabinoid system your ECS. How can you fortify your ECS? You make sure that you have enough sleep, you make certain that your diet is rich in polyphenols, which of course you can supplement with altrantil, and you make certain that you have the correct macronutrients for your ECS to lift up which you can get with a formidable or reputable CBD which kbmd health has both of those things. So in essence, if you want you don't know how you're going to get hurt, a lot of people don't know that they're going to have a heart attack today had a patient today. 172 poundsKen Brown I thought you were gonna say 172 years old and I was like wowEric Rieger Six foot one Well built man. 172 pounds 49 years old, has been doing jujitsu and Taekwondo for 30 something years. Heart Attack had a heart attack back in 2012. Undiagnosed cad, the guy's got, which is coronary artery disease, the guy has two stents in. My point is, nobody knows you don't know when you're going to be susceptible to something. So if you can, he was doing what he could, right he was exercising. So he was doing that part, right, but maybe something else that he could have been aware of...Ken Brown I'm telling you, we're going to learn that the endocannabinoid system plays a much bigger role in this and we have seen diseases start happening earlier and all that stuff. Eric Rieger KBMD health GCP code GCP save 20% on your signature package. Ken Brown 100%. So the bottom line is that there's tons of supporting evidence that exists for the involvement of the endocannabinoid system and the pathology of a stroke. Now clearly, this is super complex and we're just getting into it. And these researchers that are coming up with conflicting data about trying to block CB one or trying to agonize CB two, don't, don't do that what we really need to do is just make sure let your body do what it wants to do, when there is sufficient anandamide, which is the one that we know really kind of helps out, it will work like a traffic cop and keep the receptors in check. 2ag is probably necessary for certain things. So if we're doing this show, and you start to well, like I'm like, okay, bottom line is if I'm looking at you, and you're talking to me, and all of a sudden you start slurring your speech and half your face starts drooping. Yeah, you look like you're having a stroke. First thing I'm going to do is run and grab a whole bottle of KBMD CBD and I'm gonna shove it down your throat because at least we know in animal models, that makes a big difference. And then I'm going to go get a bunch of other supplements that we're going to do a whole nother show on that should be protocol for every single stroke center in the US. So much like the butyrate podcast, we got another one that we're getting into and I'm gonna bring a neurologist on and I want to bring an expert so that we can talk about it Eric Rieger Small request, if I'm having a stroke and you're going to do all that CBD also get a speech pathologist to make sure I can swallow.Ken Brown Yes, we will do all that if you're having a stroke, but I'm not trying to be a jerk about this, but we're going to finish the show first.Eric Rieger Cool.Ken Brown So, I mean, if it starts happening, try to do it towards the tail end of the show. You know, do you know that I've had four heart attacks since we've started this. This whole podcast show but I just suck it up, move on. I've had all kinds of health issues.Eric Rieger That Believe it or not is going to go down to the books is our first short episode. Ken Brown Well, we want to do a short episode because I feel like we're getting a little too sciency and I want your feedback. I mean, quite honestly, do you like the science you not like the science? Do you want the guest? Do you not want the guest? But when I find stuff like this, I have to let it out. And if you gave me Two hours, I'd be talking for two hours. So this is just a way to control the amount of vomit that I do right here. But it's so cool. How are we not doing this? Eric Rieger I don't know. But I think I think will change though. And thanks every single week and thanks to Paul. we're gaining viewers. We're gaining listeners. This last week was a huge spike in the last seven shows. So thank you.Ken Brown And you want to know what people are reaching out on their Insta they're messaging me on Instagram and they're asking medical questions. I love that I'm we're going to do shows on that stuff. So if you've got questions, let's do this. Eric Rieger Definitely. that's gonna do it for episode number 34. That was strokes and the endocannabinoid system. We will in the show notes, go ahead and add unrefined bakery, their offer is still good. So save 20% if you want to have keto friendly, no gluten, paleo friendly, whatever kind of meal that you're after, and you feel like you can't have bread, they've got the solution for you unrefinedbakery.com use code, gutcheck and save 20% Ken Brown Yeah,so once again, please do us a big favor. What we're trying to do is really spread this message of functional health. share it with everybody, get people calling in, get people asking because we've got the resources. we're gaining a little bit of traction here and this can be really fun. This was such an eye opener for me. Endocannabinoid system and strokes. All because somebody said my dad had a stroke Ken Brown and Tim power thanks for reaching out. certainly appreciate it. gut check project. In the books go to gut check project. com share, like and share and we appreciate it.

SCFAs Control Your Health: Why Short Chain Fatty Acids May Influence Disease

Play Episode Listen Later Feb 20, 2020 67:20

All right. Welcome back. It's gut check project, Episode Number 33. I'm here with your host, Dr. Kenneth Brown. I'm Eric Rieger. Dr. Brown. What's happening In a day?Not much I tell you what, this is really cool Episode 33. It's you and I know guest because we got to cover some serious science. Yeah, we do. A lot of people want to know what happens whenever you take certain things that works as post biotics, not just probiotics, but what do I do to feed my bacteria? And is that even number one? Is that even a real thing? What's a post biotic? Do I care what happens with the foods that I eat and what my bacteria does with it? And if I do, what's happening? so I'm going to, we're going to deep into deep into, we're going to dive in deep into some awesome science about what happens when we take care of our bodies, bacteria. Well, the reason why I wanted to get into this is that we got tons of feedback on the fecal microbial transplant episode. And then of course, when we had Panez on here talking about Crohn's disease. Yeah. So one of our viewers, Don sent me a message that basically said, so I'm more confused than ever. What do we do now? I started looking into it, and I'm like, Oh my gosh, now I know why so many things happen to poor Heli I, we're going to talk about that we're going to look into this, and hopefully clear up a few things. But I love the fact that we have viewers that are calling in be like, great episode, but now I'm more confused now and you know, follow it up. So that's what we're going to do today we're going to follow it up and talk about how Heli and Panez that has groans and Ellie, with her horrible autoimmune disease and everything like that with her fecal microbial transplant. I'm now starting to put the pieces together. I'm moving this big bubble of Venn diagrams, and I'm like, Oh, my gosh, this is here. So that's what we're going to do today. Your job because I mean, when I mean, I got excited, like, I my hair started going up in my arms. I was like, it's there. We're missing this. What I'm going to do right now is talking about some stuff that probably should have been put together before or maybe it has been maybe, but I looked at a lot of research I spent I just went down rabbit holes, and I'm kind of excited to talk about it.Well, it's awesome. It's easy to do. I can tell you that I would imagine that we're probably going to talk about not only post biotics, but some really cool names like short chain fatty acids, right? We're going to head that direction?We're going to talk about that ..PolyphenolsWe're going to talk about SIBO, its IBS, all that stuff. PolyphenolsThis is gonna be a great episode. If you if you if you're truly interested in gut health, you cannot ever stop expanding your knowledge and understanding why people say, health begins and ends in the gut. If there's a reason why that people who change your diet feel better, and this is what we're going to talk about today, so.. Yeah, totally. But you know, but before we get into that, we're not just, we're not just podcast nerds. I have a life. Okay. I'm pretty excited. I went and I did Rachel Sheers podcast, Sheer Madness. With her little Frenchie thingy Bulldog, yeah, called Lily. And so we went and did that. That's gonna launch here pretty soon, but you can see pictures of that. So that's cool. Um, and I also feel like I've been working too hard and people ask me, they're like, you know, do you have a hobby I'm like, wow, I'm..No so I was watching 60 minutes and I don't know why I'm turning into my dad. We're now I watch 60 minutes on Sundays and rather enjoy it. But I'm gonna pick up falconry. In fact, I've picked up falconry.That's amazing. You've already done it in such a short amount of Yeah, specifically Golden Eagle falconry. OkayYeah. So basically I watched a 60 minute episode and Mongolia Nomads depend on animals to get other animals because they have no agriculture. So what they do is they make this bond with golden eagles and they use them to hunt other animals for them. And they've been doing this for thousands of years. Well, there's a woman named Lauren McGough. She's a PhD, she traveled to Mongolia. She's from Oklahoma. Oh, wow. Yeah, like, imagine having that conversation with your dad. You're like, I'm gonna go to Mongolia. But she's from Oklahoma. She found this old book on Eagle hunters. And she's like I'm gonna go do this. So she figured out that this is such a unique way of living where you live in unison with the animals. So she went there, she captured her own Golden Eagle bonded with it, and then became part of their tribe and hunted with this thing. Wow. And then has come back and it's been like, you know, a conservationist and she's a PhD and she lectures and all this other stuff. So these things, she owns her own eagle and what they do is they there's, they describe how you actually get it, but it's safe and everything in the ego bonds and then they let the ego go, like you're back out in the wild. I'm done with young either, you know, do you want to leave like when the ego wants to leave, it just leaves, but it hangs out so they can fly 50 miles an hour, and they can see seven times better than a human. And then they let it go. So anyways, I got into it. So I got my first Golden Eagle. And I've been trying to do this, but it just keeps bringing the neighbor's cat to me. Yeah It's not working the way it did on 60 minutes.While like he keeps bringing the neighbor's cat so it's unharmed, which is really really sweet.Totally unharmed. It's it's a completely loving eagle, the cat loves it. I just pet it for a little while. Yeah. Then it delivers it back to the neighbor. I don't know where the neighbor is.. Could be different city who knows? Travels 50 miles an hour. It's common knowledge of birds of prey just don't ever hurt anything. They just want to show it to somebody. So that's my hobby. Yeah, interesting. I can't even match that. So probably not going to the boys are about Star basketball playoffs. So that's what we're getting fired up to do. weekend was nice. Did some camping Saturday, Saturday evening. Woke up to beautiful sunrise Sunday. It was it was awesome. And that really kind of what we did this weekend is can take it easy. So..Good for you. Taking it easy is good. I want to bring up one in the news article that I saw because pretty cool. Yeah. All right. You're gonna love this. Just published this month, actually. It was published the February 14th. So in the news, the American Heart Association published a study out of Northwestern on peace. With peripheral artery disease PAD, also known as PVD, peripheral vascular disease. Now peripheral vascular disease or arterial disease is a narrowing of the arteries that reduces the blood flow from the heart. So the further away from the heart. Imagine you have coronary artery disease. Same thing happens all over the body... But the further away it gets, it can actually affect people where you can't walk very, very far and it affects over 8.5 million people 40 years of age or older nationwide. It's a big deal. Sure. So this is so cool. In a small study of 44 people at Northwestern University of patients over the age of 60. They gave them a beverage drink containing flavonoid rich cocoa.Interesting.They gave them cocoa and then they added some epigalic tannins to it. Hmm, sound familiar?Thats polyphenol people right there polyphenols, they gave people polyphenols the American Heart Association is now starting to catch up they're, I think watching the podcast. I'm sure they are. I think they are. So basically what they did is they showed that people that took this three times a day for six months, which shows that it is a supplement three times a day in a cardiac diseased laden population, ... no side effects... three times a day, six months, and they improved their six minute walking test compared to those who drank the same number and type of beverages without the supplement.It's funny you say that because people who have serious complications with diabetes that ends up with PVD or PAD, oftentimes, they end up doing that walking test, especially if they have numbness in their feet, or they notice that they have sores on their toes that they're unaware, but a family member sees, right?YeahSo just a side note, if you happen to have diabetes, it may, it may behoove you to keep up with your polyphenol intake daily.And it also may behoove you to listen to the rest of this podcast because I'm going to get some cool stuff but so look at this.. so you're like, Okay, well what does that mean? So if I drink cocoa notes cocoa enriched with epigalic, tannins, same tannins that we have in Atrantil the right part, those are the polyphenols. So those that drank this, they improve their muscle function over the placebo. But what's really cool is they showed that they did muscle biopsies and they showed increased mitochondrial activity. It improved the mitochondria increase the blood flow through through..The mitochondria what are you saying?No, no, it increase the blood flow because of the polyphenols through..?ArterialDilation, because of nitric oxide production. Okay Everything that we've been talking about.I know he's teeing me up folks, I really hate them. Because there was lots of through there and andYeah, I'm just just follow this basically.. We now have scientific reasons why polyphenols improved sports performance, okay. It affects mitochondria and it increases the blood flow. Now we're into a much better realm. And I understand the categories that we're in because we've multiple times referenced the studies that Joe Botel from from England was talked specifically about increasing nitric oxide, specifically in athletes to increase blood flow, increased performance, etc. So sorry, I didn't see the T up there.Well, this is what's so beautiful. We always talk about, you know, athletic performance. Now we're talking disease. Now we're saying that, okay, yes, if you're a triathlete, or if you're a marathon runner, but there's a whole lot more people, you want to see how many people actually have peripheral vascular disease. Go to the airport. I remember and this is a man, this was a I remember when I was flying. I think the flight was going to Florida. Oh, and so there was quite a few people over the age of 60. They were all in shorts. None of them had leg hair.Oh, well, and circumference right..Circumference. All the way ... So just so you don't get along because I'm one of these if you still have hair. On one side of your leg, but on the other, that's not what we're talking about. But if you have a, there's like a line of demarcation... And then suddenly the hair stops you, you probably need to at least be checked out because there's a lack of blood flow.Yeah. So what ends up happening is is that the blood flows to go from the heart all the way to the toes. And so the micro vasculature starts decreasing before the macro vasculature meaning you're going to sacrifice the skin, blood flow to protect the muscles and the joints and the cartilage and all that other stuff. So that's how many like I looked around one day and I was like, Oh my god, I truly believe that almost everybody here has coronary artery disease slash PAD. Now we're looking at this going they all need to be on a polyphenol..Yeah, absolutely. Yeah, that's really, really interesting. And that's crazy. So yeah, so these these polyphenols definitely will help naturally benefit and produce nitric oxide so that you can increase your blood flow. And if you're already compromised help your body out.Do it never even thought about the whole mitochondria thing.Now? Obviously I didn't either, because I just sat there and stared at you. I saidYeah. Now the question is they didn't get into why they're actually asking in the article at Northwestern. They're saying the etiology, or the the physiology of how this is accomplished has yet to be determined. But we know it increases nitric oxide. Yeah, we do. I'm going to get into some stuff here shortly where I'm going to tell you that it's all about the post biotics. All right It's nuts. So for the next so I'm going to that's, that's it. That's our that's our fun part of the podcast.Now, that is fun, though. Honestly, if you've got circulatory issues, at least, you know, there could be a natural solution that will at least help. Number one, give you some more time. Number two, give us an idea of what you can do to improve things for yourself.So I mean, if there's one reason to do this podcast, and I keep saying this every single time, but I'm getting I'm learning I'm getting better. We've got our little secret weapon that keeps sending me articles and I'm just like, Oh my gosh, this one ties to this this one ties to this. So this is going to be a review of short chain fatty acids and you're like, I don't own any of those. I'm gonna get off. No, you need to hear this. Basically if you're a mammal on the planet Earth, this is a really important podcast for you.If you can understand the words he's saying that is you... yeah. Unless you're a flat eartherYeah, well they probably still should take they still take polyphenols..Should I shouldn't take that back question discriminated against. Unfortunately, I just watched that Joe Rogan episode with the astronauts. I'm all about space right now.Oh, yeah. Well, it's funny just the other day I passed the flat earth mobile in Denton, Texas. Yeah, it's pretty fun. On the back it says the earth is flat and you pan down to is buffered it says and motionless, which I think is awesome. But whatever. Well, so let's get into short chain fatty acids post biotics. Let's, let's get into some some awesome science here and, and let people know why it's so important.Alright, so I mentioned the very beginning that this was sort of brought on because the viewer Don said, Well, what next and then I started going down this rabbit hole, then I started Heli. If you watch the episode where we do the fecal microbial transplant This is that mean that she's not an actress, she's desperate. Sure. And things are happening to her and they're happening fast and she is panicking. We had Pannez that is at risk for all these things that we're talking about, but it's super complex. Ultimately, it all comes down to the microbiome. Unfortunately, As Americans, we disrupt our own microbiome by our lifestyles, like eating crappy diets, taking antibiotics, lack of exercise, and probably poor sleep are the biggest deals. And this is going to result in a decrease in diversity. You're going to hear this term over and over and over again. People always talk about I'll just take probiotics and improve this. No, it's way more complex than this. We're going to get into it. But basically, you need a true diverse microbiome, to aid in your health. Researchers are now showing that neuro degenerative issues like dementia, Parkinson's, anything that affects your brain. And you know, Eric, we've talked about this a bunch that my goal as a physician right now is to figure out a way to stop dementia. Yep. Because we come on the show and we talk we talk about our kids or about our wives. We talked about stuff. Imagine if all of a sudden it's gone. What was your life, ultimately, your life becomes memories and those memories are what forms your personality and all these other things, and then they affect stuff. The thought of taking away my memory is, I mean, people people don't really think about how, how difficult dementia really is. I mean, it's it's a it's a hard one. I've had friends whose parents have faded that way? My wife's grandmother, I mean, we wonderful woman and went through just honestly her own living hell not being able to relate to the people that she felt like she knew around her. And just it's no good. No. And so if we can sit down, start piecing things together. Yeah. And not only the neurodegenerative things, but now researchers are starting to look at this. I mean, I just gave that article about the American Heart Association looking at a polyphenolic complex. That means that the traditional medical complex is starting to look at this stuff starting awesome Starting.Now there's evidence to show that heart disease, heart attacks, strokes, diabetes, obesity, so if you're like, Oh, I don't know anybody with dementia. But do you know anybody with obesity, ever had a heart attack? You have a family history of anybody with diabetes? Any all that stuff is the real question is how and why? Yep. Why didn't Heli develop all these autoimmune issues after fecal microbial transplant? My theory I'm not I'm not a smart enough to be a flat earther that has cool bumper stickers like that. But so my theory is just looking at all this and looking at my patients. I'm not a I'm not a PhD bench researcher, but this is what the world needs is bench researchers coming up with stuff having animal models, clinicians out here, slugging it away, and weirdos getting on the air and talking about it yet try and figure it out. Yeah, bridge bridge the gap between traditional medicine and natural solutions. Alright, so my theory is that our microbes, our microbiome, the most important thing in your body that really helps regulate everything. Do we live for them? Do they live for us? We don't know. But it can be symbiotic. Meaning you can work together. They're fed by the food we eat specifically fibers and complex polysaccharides. polysaccharides are hard to digest starches, right? So through various mechanisms their, these bacteria break them down, they eat it. And then their waste products or basically what they leave over. We use .. So their compost is our fuel, right? It's a fantastic thing that we've never really thought of before..Their compost is our fuel. That's that's, yeah, it's nice.Yeah, so that's what we're now calling post bioticsRight? And it's not a bad thing at all because what they produce in general post biotics, you can describe post biotics by their composition, like is it a fat, short chain fatty acid? Is it a complex molecule that we don't really know very much about it? Or does it do like your religion is one of them, your religion that creates the Mito con the mytophogy, right affects old and sick mitochondria.And if you're keeping up that's also known as the anti aging post bioticProduced by bacteria that breaks down these things a post biotic or the physiologic function that it causes. So we know that there's certain things about to reproduce that we haven't been able to label yet. There's been 800 post biotics, and they create all kinds of different diseases Again, 800 post bioticsThat scientists have at least discovered Right. And it's just to be fair, it's much like the ocean, there's just because we have 800.. I don't even think we're near the end. I mean, there's lots to figure out and the combinations thereof anyway, I don't want to sidetrackNo, totally sidetracked the whole time. In fact, your sole job, because I'm like, when I mean that we discovered a topic here that I was like going, Oh, my gosh, we're, we're piecing things together. So when I start going down a rabbit hole too much, interrupt immediately and go, you don't you're not making any senseSure.Just stop and start me over here. So this all started because of the fecal microbial transplant thing with Heli. And then Don says I'm more confused so that I started looking into it. And now I started realizing that these post biotics there's 800 of them, but let's Focus on one that we've done some serious research on, which is short chain fatty acids..Okay? Now short chain fatty acids are fatty acids that are really small. They're like fewer than six carbon atoms, meaning that it's very tiny. And they're made by our bacteria in our colon from undigestible, or from indigestible foods like fibers. And I always thought of them as fuel for the colon. That's how I was taught during my fellowship and residency in medical school, that they're, they're local. But the reality is it goes way beyond that, way, way, way beyond that. So these short chain fatty acids do include in to the geeky part, names like butyrate, acetate, propionate, and lactate, don't get hung up on the names, but in particular, butyrate is one that everybody talks about..Right? It's super important for gut health, and it's also known to help with gut motility corrects leaky gut, it works locally to heal the lining of the colon. But we now know that the other short chain fatty acids can actually be absorbed systemically as well. And we have not been paying attention to them. And they can influence the body in all different kinds of ways, depending on the host genes..Right?So you and I may react differently to these short chain fatty acids, depending on your genes. That's the epi genetic phenomena, right? That's how come Heli he developed all these issues when her donor did not have the issues. So that's a separate rabbit hole. But what I want to talk about is butyrate is so important that most nutritionists and scientists study this molecule that is its own episode. Okay. I'm going to talk about the black sheep of short chain fatty acids..Which ones at that? Oh, everything else but butyrate it okay. So if butyrate just know it's good, and you want butyrate? Yep. Now we're going to go into everything else and I want to explain how my patients like Pannez may have developed her problem, and we're going to bring it all the way back to short chain fatty acids like acetate and lactate and talk about that. So, the rest of this is I'm going to show you the model that I've never been able to explain up until right now. Okay. For instance, every time somebody sees me with SIBO small intestinal bacterial overgrowth, or irritable bowel syndrome, IBS, or inflammatory bowel disease, IBD, Crohn's colitis, I like to ask them a question. I'm like, Do you ever feel like you're in a brain fog? Do you ever have anxiety? Has your mood changed? You have sleep disturbance? The first thing I do is go right from the gut to the brainRight? And I asked because I've seen this correlation. And I've always said, Well, it's because of the inflammatory process. haven't really gone that deep into it because all the articles I was reading about that all showed that a inflamed gut can lead to an inflamed brain. Now let's dive a little bit deeper and find different reasons how these post biotics actually lead to that. OkaySo if you're somebody that suffers from anxiety, it may have nothing to do with your brain. It may all start in your gut. And this is really wild. So step one, something happens.OkayYou get back bacterial overgrowth, SIBO you have an infection, eat a crappy diet. This leads to leaky gut, or intestinal permeability. Now, new research is showing that this will actually once you develop intestinal permeability, it actually allows acetate and lactate to get absorbed more into the bloodstream. That's not really what we want is it. It's not what we want. So once it gets absorbed into the bloodstream, these short chain fatty acids have this incredible mechanism to cross the blood brain barrier through its own transport molecule. So in the past, we've always talked about leaky gut leaky brain. This actually has its own transport, it doesn't even have to be a leaky brain, it's got a little bridge that these guys ride.So, in short, if I think this can be beneficial if you have a transport mechanism at the cellular level, basically, that just means that there's a little protein that's allowing passage or exchange of something to be taken from one side to the other. And I think that what you're explaining here is, we don't really want these molecules crossing over to the brain, but now that they are rapidly being absorbed through the gut, that they're more abundant in the brain, and that's not really what we're after.So these guys finally get out of the gut. They got a VIP card. Yeah, they're like, whoo, VIP card front of the line, let me know the brain. So that's what's really fascinating. So acetate and lactate, once it gets in the brain. They can actually directly influence neurons. causing a series of effects. said again, it's a direct neuro transmitter. Nobody's ever said this that I've learned this in neurology..Yea me either. So lactate and acetate can cause a direct influence on the neurons by stimulating sympathetic nervous activity. What that means is..Excitability.. They turn on the fight or flight.Yeah, interesting. Well, guess what? Yes.So this can cause a rise in blood pressure, heart rate and the opposite effect in the gut. When you have a sympathetic effect in the brain. You have a parasympathetic effect in the gut. What I mean by that is, I always tell my patients, the more because they're like, oh, man, I've been so stressed. I built constipation. Like it's a physiologic phenomenon when we were evolving. If you're being chased by a saber toothed tiger, you don't want to have sex or take a poop. Right as you're getting giddy. Yeah. So you have to think fast and run. Yeah, it's really funny. So like, I'm always thinking about that, like from sex. To actually have an erection. You have to have a para sympathetic response. wants to have an orgasm you need a sympathetic response and to actually have a bowel movement you need a parasympathetic. So parasympathetic is the opposite side of the fight or flight..Right. So now we've got this thing. I'm like, Oh my gosh, wait a minute. So, when you have SIBO, I'm just going to keep using the SIBO patient because, for the first time, I could say, oh, Heli on the interview, kept saying, I just am so anxious and just in and remember, I took a two hour interview to 15 minutes. I really kind of had to get her back focused the whole time. She was just like, I'm just wired and not wired like Robb Wolf. Alright, so then this becomes this really wild, this sympathetic effect causes a rise in the blood pressure, heart rate, and then the opposite effect, where then the motility gets messed up leading to more leaky gut. It becomes a vicious cycle. Yeah. So then while all this is going on, more inflammation happens. In the gut, the leaky gut then turns on the inflammatory cascade. So then that becomes our normal talk. That's I've given lectures on this part where I can show interleukin 12 and other 23. You know, cytokines blah, blah, blah, histamine..These are all inflammatory markers. Yeah, yeah. Oh my gosh, what if the very, very, very, very beginning of it is too much lactate acetate getting into the brain that then tells the brain to turn on the gut, or to turn down the gut to create more inflammation. And now you've got this process going on. So we've talked about this for SIBO in years, but now I'm saying oh, my gosh, we gotta fix the post biotic situation before we can fix everything else. Yeah. So now you may be thinking, Okay, this is crazy. I don't have you know, it's, it's interesting. I don't have anxiety, I dont have depression, I don't have bloating, I don't have gut issues. I'm going to turn this off dope because Oh my goodness. Now we're going to look at some different things that these post biotics are actually linked to certain diseases..Okay. And now we're going to get outside of the gut. And I'm going to give you mechanisms about how these things affect or can create diabetes, blood pressure, dementia, all kinds of stuff. Before we jump too far ahead. Can you give us an idea on what type of foods are used by these bacteria to create the post biotics that we don't want?..To create the post box that we don't want? That's that is a great question. What we do know more is that the foods that produced the post biotics that we like are fibers, and digestible starches are resistant starches, things like that, right? overnight oats, you know, whatever type of fibers, polyphenols, the skins of vegetables and fruits. What we do know is that when you eat a diet high in processed foods.. you end up creating more bacteria that produce more lactate and acetate.They're the things that I was kind of hinting at. And I kind of cheated a little bit but the things I was kind of hinting at were unrefined, our refined sugars. Yeah. And things like oils that we're not really supposed to consume like high, high pressed vegetable oils and different things like that they, they believe that those may be the the foods that allow the bacteria to produce the postbox that we don't want preservatives, foods that shouldn't be sitting on a shelf for months at a time and suddenly they're just fresh because they're in a package. Those may they don't know this for certain, but they think that those may be the kinds of foods that would lead to a lot of this lactate and acetate.And nobody's talking about the post biotics doing this. And spoiler alert, I'm going to get into it a little bit. But basically, once you start producing more of it, you're it sends signals to those bacteria that are like we're winning..let's keep doing more. Yeah. So they end up propagating more or they end up colonizing more. whatever word you Want to use? Then you end up with more of that. And then they're sending brain signals to eat more of that. And that's that whole thing where now you're out there wondering why you're cracking open a bag of Oreos? Well think about it if if I post bodek is influencing the way that my brain thinks she would have to draw the assumption that if I'm suddenly addicted to sugar, and I'm always craving sugar, whereas maybe I didn't before but now everyone my friends would know me as someone who just really likes sugar all the time. That could just be the the lack of that post biotic influencing the brain who's now told me Oh, you need to quickly go get this fix to make you feel this way.Oh, I'm so glad you went with sugar on this one. Nice. Let's talk about diabetes. Okay. All right. So I found an article that basically looked at diabetes in a rat model. This research showed that diabetic mice fed a sad diet, a standard American diet, and this diet which is high sugar, high fat, high fats not bad, right? High. I think high sugar is always bad, right? You combine the two and it's a, it's horrible. Basically, they fed us they fed these diabetic mice a sad diet, and they showed immediately that the acetate level jumped right up. This rising acetate caused an acute rising glucose leading to the pancreas to secrete excess of insulin Yeah, then it should have and then this rise in insulin led to a huge rise in a hormone called ghrelin. Ghrelin..Hungry. Yeah. Can you go ahead and explain to everybody what ghrelin is. So,Ghrelin is the the mechanism by which your your gut, your GI tract tells you that you're hungry, and you're going to want to go out and eat. And you really want leptin to kick in and whenever you've not, or when you whenever you don't need to go out and get hungry, basically. I mean, so whenever you see the commercials for what was The name of that lipitor or whatever it was, it was making people feel like they were. They were full. They were they were basically trying to mimic leptin. Really?Yeah, to make you feel full. Never saw. Not only works, butBe around. But regardless, grillin is the opposite. Ghrelin is the one that drives you to go and seek food to go get nourishment. But it's funny because they started to think and you could be, you could correct me on this, but ghrelin it certain instances, like for the sugar lack, that if you get low on sugar, then suddenly your brain is now programmed. Well, we'll raise ghrelin whenever our sugar load gets low, right? Yeah. So what was so cool is that these guys looked at, usually somebody will look at one thing, but they're like, okay, our theory is this, we're going to look at the post biotic acetate and see what its effect does. And those that have higher acetate levels are showing higher insulin, higher ghrelin levels. And so then those mice became voracious. They want to eat more than what did they do? They produced more and their desire to eat the crappy sugary type stuff because the ghrelin is saying get the cheapest, easiest calories. Yeah led to higher acid..acetate. Yeah, wait. Just Just a side note. This is also the argument that a lot of dietitians have on why it's important to have what they call high density foods. So a refined sugar is not a high density food at all. It's short lived in terms of the satisfaction, and you're going to always want to keep consuming whereas if you eat the foods that you should eat, you the fibers and the polyphenols, etc, you you fill up and it leaves lots of work for the bacteria to produce the types of post biotics that you want. 100% so I have all these diabetic patients that struggle to lose weight, but really, it could come down to the bacteria and the bacteria that are producing acetate. I mean, maybe the future treatment. I mean, American Heart Association just got done doing this studying peripheral vascular disease. Maybe the encrinologist will start looking at changing the bacteria to help with diabetes instead of just throwing drugs at people. because quite honestly, once you get put on insulin that it's it's erases your ghrelin everybody I talked to they're just like, man, I take an insulin shot. Bodybuilders take insulin so they can eat more and their growth hormone goes up.Yeah, kids don't do that. That's not the reason.So diabetes, I don't care about diabetes. Nobody. My family has diabetes. It is what it is. That's what somebody out there saying, Man, this guy keeps talking about anxiety. SIBO IBS had an effect me or anybody in my family. All right, I'm telling you that. Now let's talk about blood pressure. The silent killer.Definitely How many? Honestly, side note how many times do we have patients come through every day? We have a full load. I would say probably 20% of those on a full load day. We probably have to inform them about a blood pressure issue right or wrong?Oh, we've seen more than 100 million people in our clinic. Yeah. Wrong. That's that's wrong. That's 100 million people have high blood pressure in the United States. Okay. Yeah, we seen 100 million feels like 100 million.Yeah, I didn't know what that number was going. That sounded like an awful lot. But, but we do, but we do have people who for the first time ever, it they say feel fine, no meds. And then suddenly we look at their blood pressure, and it's 170 over 98. So not normal. And I've been pre hypertensive for a long time. I've changed my diet. And you know, I'm knocking right on 49 right now. So I'm pushing 50 here, and my blood pressure is better. It continues to get better as I focus on my dietRight? And I've always like, Man, that just doesn't make any sense. Why would because, you know, I, you know, I'll sit there and I'll fly off the rails and cheat and pizza and stuff. Now we're going to get into some of this stuff. So the American Heart Association says it over 103 million US adults have high blood pressure.That's a lot.I still think that there's more people that they don't even realize.100% because there's only what 300 I'm guessing here. 340 million people in the US something like that.Yeah. And so high blood pressure leads to stroke, blah, blah, blah, blah, everything else, you know, it's that whole syndrome x thing. Yeah. So Oh, by the way, you know who does a really good job of explaining the whole syndrome x, the ne ne coined the phrase, it is Rob Wolf. Diabesity.DiabesityDiabesity. In his book, The Paleo solution, yeah, he actually describes this whole process of what I learned a syndrome x he's calling diabesity. And how once you get into this pathway, what I'm going to say is maybe this pathway, this shift is now we have a mechanism that these post biotics are actually creating this whole diabesity issue..Wow.. they could be and this would be obviously a step in the right direction. So do remember the whole thing that I told you about the sympathetic neuron activity so acetate and lactate get in there, their little free pass VIP card. Yeah, and then actually poke on the nerves chair and they turn on the sympathetic system. Well, researchers showed that young pre hypertensive rats exhibited leaky gut protein expression. They were pre hypertensive, and they were looking specifically at leaky gut. I don't know if it was zonulin or whatever they were looking for. But they found it before they were hypertensive. Starts in the gut..Definitely Crazy. Now, the more signs of leaky gut, the more sympathetic output these rats showed, increasing the permeability led to increased brain permeability. And they showed that acetate and lactate stimulated an area of the brain called the hypothalamus,Very important master glandMaster gland super, super crucial thing. Now, this actually increased the sympathetic signals leading from the hypothalamus down and blood pressure started to rise accordingly, as asked lactate levels went upThat's a no one's really built that, that that pathway. I've never seen anybody do that.It's, I mean, I read this and I was like, What? How are we not describing a treatment for high blood pressure, diabetes, obesity and thinking more about the our microbiome than just throwing? I mean, how many of my patients have six, seven? I mean, you take a beta blocker, what are the side effects of that fatigue, depression, erectile dysfunction, then you take calcium channel blocker, and you've got cough, and you've got ankle edema, and we're throwing this stuff, and all of a sudden, we've got rats where we can show if we decrease this. More importantly, they show that the sympathetic shift, altered the microbiome, which led to a less diverse microbiome and increase in lactate and acetate producing bacteria. One more time it got into the brain, the brain sends signals to the body. That is you're in fight or flight. Yeah. And because and have, you can logically try and work your way around this. But basically those same signals, tell more of those bacteria just like you talked about with the sugar..RightNow more of the bacteria are being signaled to grow. And now you've got a cascade of high blood pressure type stuff. Unfortunately, it sounds like what what we're doing is building a friendly utopia for the bacteria that we don't want, right? And then they're basically telling your brain to go and get some more the food that will allow them to build more of the byproducts or the post biotics that you don't need that are going to make your problem worse. And just a side note, so overstimulation of the sympathetic nervous system. It's really funny how we're talking about diabetes, we're talking about high blood pressure, we're talking about insomnia, we're talking about anxiety, all of those things are just simply going to compound and make the same situation worse, the diabetes gets a little bit more out of control and the insulin goes up and the ghrelin goes up. I'm gonna keep eating. And by the time I keep eating and I post biotics make my anxiety level go up and I can't sleep, that's only going to perpetuate more of the same and you can only I would assume, correct that by getting the right bacteria to eat the right. the right food, so that you have the right post biotics, right? That's exactly it. Just that easy Eric. That's all you got to do. All right, well I guess thats it..Mic drop spoiler.But it just it's it's scary, though, that that quickly, you can escalate while you actually have no idea that it's happening to you. You just don't know. You're not in control. No you're not.So I mean, here we have this deal with a rise in lactic acid acts like a positive feedback loop to create its own little lactic acid factory.It's self serving. It's not in here for youNo, those bacteria, everybody We talk about an ego centric society and everything. Well, as it turns out, I'm learning more and more that bacteria are truly egocentric. AlsoYou gotta keep them in check. You know, C. diff would love to just run rampant and do this. See that being a bacteria that when you wipe out other bacteria due to antibiotics, you end up with horrible diarrhea. That's something we deal with all the time. They just be they have this they throw this big party and make you really sick.. so the bacteria themselves, they have a self serving need to keep growing. They're not looking around going. I need more diversity here. Everybody wants to win. And when you have lactate producing bacteria they want to win. That goes back to the whole Satish Rao article where he gave SIBO patients probiotics, and they produce more lactate. He checked the lactic acid levels and those people that had higher lactic acid levels had higher depression and anxiety.Damn, that's not good. That's not what you're after. So what we're looking at here is microbial dysbiosis micro dysbiosis is the term that the natural path to use everywhere. And really what that means is a lack of diversity is not dysbiosis. It just means that there's an imbalance in your microbiome, you have too much of something and not enough of another. They showed with rats that those rats with a lack of diversity tended to have higher levels of the lactate and acetate. And, again, not the post biotics the short chain fatty acids that we want. So understanding that knowledge, these researchers started to look at stroke and dementia. And getting back to the brain. Yeah, so using that model, they were able to show that acid and lactate can cross the blood brain barrier, which we've already discussed. Then these guys focused on one unique thing I already discussed how they tap on the neurons and do this. Well. Something else that that these post biotics short chain fatty acids do is that they actually lope they actually dropped the local Ph. So this local drop in pH caused inflammation At the neuron level, this inflammation led to increase in certain markers of inflammation like human necrosis factor, and it causes cell death.So just in layman's terms, why that matters is if you drop the pH and basically you are creating a more acidic environment. And just a side play, which we haven't even mentioned yet that actually creates more work for your respiratory system to basically correct that. And by you know, I'm saying because you have to blow off the acid your blood, but your blood buffering system is going to have to produce more bicarbonate just to basically take care of the neurons that are now in a more acidic environment. This is exactly why whenever you're an athlete running around, you breathe heavier, right? Because the acid formed by the activity throughout all your muscles is dumping into the bloodstream so that you can breathe out co2, well, if you're not running around, you don't really want to be dropping your pH systemically. So that's That's a big No, no, that's not what we're after.So once you have a cell die, that leads to oxidative stress... which ultimately leads to inflammation. Those rats develop dementia. So chronic inflammation..Chronic inflammation. So we've always talked about chronic inflammation. This is first domino effect. Yeah. The first domino effect is this we're getting into a cellular level. They even took normal tensive rats, so rats with normal blood pressure, and they gave a microbial transplant fecal microbial transplants on mice that were genetically prone to have high blood pressure and strokes, okay. And the rats who received the transplant developed high blood pressure and had strokes. So watch the episode where we talk about Heli. Like once I'm getting into this, I'm like, why would we do fecal transplants without knowing all of this? So let's break that down real quick. Basically, what you're saying if I understand correctly They took the bacteria that was somewhere else and put it in another rats colon. And they were able to replicate that these bacteria when fed with the wrong stuff being the wrong count of bacteria wrong diversity count, right? They gave off post biotics that lead to more damage to the rat itself.So the so the rats that they euthanize when they saw that they had strokes or that they had dementia, they show that they had much higher levels of acetate and lactate, the rats that lived surprising, not surprisingly, at all, actually, now after looking at this, right, the ones that did not develop high blood pressure or have a stroke had higher levels of all short chain fatty acids, but they had higher levels of butyrate overlapped. So they had but they had they had the right concentration. Right?They had the right concentration. It's not that lactate and acetate should never be produced. It's that they're they're being overproduced at the expense of what's healthy for your body.And so one other thing one other brain disease that I want to get at and then we're actually done with these diseases. But I hope you're seeing that we have diseases that are specifically related to this. Yeah. So can you smell me and tell me if I Parkinson's? Hang on a second?That is not something I can detect.But somebody can because you sent me that article.I did. Yeah. Tell me about that.Well, there is apparently a woman who has a, I can't remember what the study is you kind of put me on spot here. But basically, she was able to show all but less than 3% of the people she was able to identify disease states in them and one of them was parkins by a smell or an odor they put off which I found fascinating. She was able to accurately diagnose people by the the odor or the the pheromones or whatever it was that she detected. And then of course, you did a little bit deeper. They talk a little bit about why so..Yeah, so as it turns out, so this woman, her husband, died of Parkinson's, and when she was in support groups, she remembers her husband smell started to change like a decade before. Then he started developing symptoms.Oh, you know what, I'm sorry, quick shout out my youngest son Mac. He's the one who showed me an article did it Really? .... Cool. So it's, I looked at the they believe they've discovered what molecule she's actually smelling through mass spec. But that's kind of irrelevant, because what's happening is is now I'm linking that to this. Because evidence is now showing that dementia and Parkinson's begins 10 to 20 years before the brain is actually affected.And if I remember correctly, further down the article didn't they say they were experimenting with her to try to find alzheimers? Correct, correct. Yeah. So everybody's like, Oh, this woman's got this magic skill. What is she's smelling? Yeah. Acetone when I go into ketosis.. I have acetone coming out of my breath. Right Haven't you you've actually smell different what you're breaking down. It's ketoacidosis Severe diabetic Or severe diabeticsfruity acetone, head on.They have the fruity acetone..So we definitely put off different smells and different, you know, chemicals builder. So this is interesting Parkinson's, these diseases have build up. So Parkinson's specifically has a buildup of proteins that are actually seen in the gut first. So when they look at the proteins that create the Parkinson's disease, right now, researchers are looking in the gut, and they're finding that protein buildup in the gut before it builds up in the brain.And just so you all know that this is not made up pseudoscience, just a completely separate example, GI bleeds, going through a hospital, you can almost always tell a patient that's dealing with a GI bleed simply because I mean that that smell is unmistakable right?Oh, yeah. I mean, I think that I think other third world doctors rely on their senses visual smell.. to really try and diagnose a patient.. And they get a little bit more deep in it kind of thing.. So that you know, there's the when I did gynecology, you did what was called With test, which is the pap smear when you try and smell a fishy odor and things like that, so we don't do that much anymore because you said it to a lab, but..Yeah, hard to do.So these, these diseases Parkinson's could actually develop early on. Now what's really interesting is that Parkinson's could be related to the Vegas nerve.Parasympathetic.Causing the inflammatory buildup of these proteins. Interesting. So rats given a fecal microbial transplant from a Parkinson's rat immediately showed an increase in acetate levels. Then when they followed these rats, they slowly developed motor function problems. In humans, we now realize that those people with Parkinson's have a dysbiosis I'll say it one more time. Now we're starting to look at all these chronic diseases and researchers are going let's look at their microbiome. Almost all Parkinson's people have a dysbiosis Wow. So people would say, Oh, well, if you have Parkinson's, you're sick. You have a dysbiosis. I'm saying no, the dysbiosis caused the Parkinson's.. we have to prevent that. Start there. So to answer in a very long winded, complex way to answer Don's question, shoot, it's so complicated. But I think we are now seeing a starting point. I think that if you keep your microbiome diverse, plenty of bacteria that can produce butyrate and other short chain fatty acids, and in my opinion, now thinking about it, that fecal transplant, getting a fecal transplant may carry more risk than we ever thought looking at these animal models. So Don's question was, Well, what do we do? Is fecal transplant good or bad and only in that we know for certain as if you have a complex microbiome, a diverse microbiome, and you feed it, what it needs, then you're going to produce the appropriate amount of post biotics, which will keep you healthy.Yeah, well, that makes that certainly makes the most sense. And to your point where you kept resetting for people who may not have known someone who has high blood pressure, dementia, diabetes, Parkinson's, anxiety, insomnia, if you exist, where you don't know anyone else like that, thank you for making this podcast, the only thing that you do to connect with other humans, because that's impossible.They're living in this utopia.It's just impossible not to know someone who's at least affected by something like that. And so I mean, it's kind of crazy to think that it all comes down or it could possibly all come down to the bacteria that we have naturally inside just simply need to be fed the right things at the right times and in the right amounts. You can make The case of I don't want to look obese I said together so not don't eat fast food. Well, the truth is, you look, you have those kind of manifestations where people aren't happy and stuff like that, because that's not the food you should be eating all the time. You've got to take care of yourself. Polyphenols is an easy way to get started.100% So, the now I'm gonna have to do a whole episode on butyrate because I went down Well, we should though.I started go down butor and then I found all these great articles. There's articles looking at different polyphenol supplements in the butyrate elevation that they are. Watch the plant based episode with Dr. Juan. Yeah, because he gave me his Neo greens as a sample and we showed it there. I looked at it. If he thought about this, then he's I mean, he's a super wicked smart guy in there. It's he's got probiotics, fermented, fermented vegetables, probiotics, with polyphenols in there, which means that possibly, spoiler alert, again, is just it's too much. But there's, there's there's people out there that are combining polyphenols and probiotics to produce these short chain fatty acids, right and ratios that they want. And maybe not fully understanding why.Not understanding why not understand if it gets absorbed, not understanding if it's a natural way to do it, I don't know. But it's at least a step in the right direction.I'll even reverse that. The answer oftentimes, when people only add, let's just say they're only adding butyrate that's probably not the answer either. You still need the healthy ratios of butyrate along with acetate and propriate. And, and lactate, it would be odd to only produce butyrate because that will probably yield something else that nature has a great way of having Governor's on certain systems, right. So I would imagine that there's probably going to be a healthy balance a healthy ratio, which is why you want the bio diversity in your gut.I'm sure 40 years ago, Dr. Ian Quigley, the godfather of probiotic sat there with a petri dish and went his hair stood up. And he went, Oh my gosh, this, this live bacteria is doing amazing things in the gut. And then 40 years later, we're still trying to figure out how to get probiotics to people. Because in a petri dish, it does amazing things in the human body, giving one strain and now we're up to whatever who knows. 50 strains of 50 billion units. Is it really doing anything? We don't know? Is it even getting there?Is it getting there? We don't know. And this could be the exact same thing. So the knee jerk reaction would be, oh, I'll just take more beer right and then I started looking at different there's a ton of different butyrate supplements much like sulfurophane where a lot of people are trying to you know, jump on the marketing bandwagon of broccoli sprouts... And so there's very few of those that are actually viable. Yeah, now now we're which broccoli is one. That's what I like to recommend Brock elite. But I am so excited because I feel like because of this podcast, because Atrantil to because of what we're learning and the scientists that I'm meeting, it's all starting to come together and truly I feel like we are changing the health landscape of anybody who purchases Atrantil to and our whole separate episode of kicked him out neuroinflammation acetate touching this and that don't even get me started on how the fatty acids in a full spectrum hemp CBD productSureCross the blood brain barrier and start mitigating some of thatYeahI mean if I if I had Elon Musk money and I could just sit there and look at different things. I mean, like, I want to know what what this CBD product does on acetate levels in the brain. YeahAnd just start asking questions like that. Each one of these studies was somebody who had a question, and it just happened to be that they were looking at short chain fatty acids, the effect and the effect it had systemically and props to these people to start doing that because that's hard work. So in short what should someone do? Who hears, okay, I need to have great bio diversity. I want to change the way that I'm approaching stuff. I want to be able to feed my new bio diverse microbiome correctly. Dr. Brown? Where would I start? Well, just I'll tell you and I don't ever tell people to do things I don't do Sure. So and I don't ever tell people to stop things that I still do. So be careful what you ask. Number one, we need to increase the diversity of the microbiome. The best way to do that is to increase your fiber. So the fiber that means soluble and insoluble fiber, two different kinds of fiber one soluble mixes in water that's like Metamucil insoluble, it's like the skin of vegetables. What we are now realizing is that skin of vegetables has this other beautiful molecule called polyphenols at what makes vegetables colorful. So I try to take in a certain amount of fiber I try and I've now because I read this. I went to Carla and I went to Whole Foods and I got some steel cut organic oats. And now I'm just soaking them in the fridge. So now I have cold oats. And the reason why is oats are a resistant starch. If you cook them and make oatmeal, the way we do it, you make it more easy to digest by making a resistant starch. I'm going to increase the type of bacteria that produce more butyrate. WowYeah. So now since I've done the research on this, I wake up and I just take a couple spoons of these oats that are just soaking overnight. And now when I tell people that watch Dr. oz and stuff, they're like, yeah, overnight oats. Where were you in 88 when Oz talking about whatever he started. Like really, people were talking about that they didn't know why they were talking about now. That's the kicker. So one of the problems that I have is that if you tell me to do something, I need a mechanism of action. SureIf I can explain the mechanism Then it works for me. Now I'd say that I would say that I'm open to ideas also, but I don't want to change this because you say it's great. Exactly.Just tell me why. Yeah, tell me why. So, increase your fiber, increase your resistant starches. You can do the resistant starches a lot of different ways. green bananas or plantations. Lloyd is Puerto Rican. So we do a lot of plantation nice. So that's a that's a paleo friendly, definite starch.Shout out to Bubbas sells. green bananas. That's what makes Oh, yeah, they are well designed by a guy who had Crohn's disease. Right. You talked to him? Yeah, it's so Bubbas Fine Foods, you can check them out. So if you're looking for a safe snack, there you go.And then now I've got all these articles words, people are actually starting to look at that the American Heart Association at the beginning of the show, I talked about how they're using polyphenols to help with peripheral peripheral vascular disease. I know that one of the best ways to create post biotics and I wasn't even thinking short chain fatty acids. I was thinking more along urolithin and these complex molecules that these other scientists talk about, there was an article that actually showed a molecule similar to Atrantil had an increase in butyrate, a whole separate show, because that's going to be a, that'll have to be a two hour show about how to increase your butyrate levelsDefinitely. But the beauty is, it isn't like you're just increasing butyrate levels you're going to eat, you're going to increase the diversity of the microbiome and allow it to happen. And then ultimately, polyphenols, fibers, resistant starches, and I'm going to now go down the pathway of why so many of my patients feel better on CBD. I think there's something to do with these short chain fatty acids. I just did. I have not gone there yet, but we've got our secret weapon and she'll find something out there.So ladies and gentlemen, if you want to start to work on making your gut a little bit more diverse and healthy, go ahead and get your soluble insoluble fibers supplement with good trustworthy polyphenols. There's nothing wrong with controlling inflammation systemically with a good CBD a good diverse whole foods diet that's really coming down to and I'm about to try your idea for overnight soaking oats I've never done that beforeI just started doing it. And if you don't have, like if you're lacking diabetes, you don't have enough high blood pressure. You're not obese enough, then ignore this whole podcast. Yeah, do whatever you want. That's awesome. That sounds great. What lots of knowledge day on the show. Thank you all so much for watching and listening, Be certain to like and share if you want to go back and check out the episodes with Heli, with Pannez, or Dr. Doug won. Just go back to gut check project.com You can find all of our episodes cataloged on there on the page this we're improving it all the time, be sure and sign up for the newsletter. Starting tomorrow, everybody who is in the KBMD health universe will be reminded of the latest published show. So if you ever get to catch up with the shows, just sign up, you'll be notified each week, every new episodes, we release it Go to KBMDhealth.com. Right. And one of the things that I get that I see the most common is rectal bleeding. And we went through the trouble putting together a little rectal bleeding free book that So download that you get a free book. And then we can keep you updated to these shows. One of the things if you can like and share this, the more this grows, the more that we get access to scientists, the more that I can take deep dives into stuff like this. If you're still listening, thank you. This is like that person that actually reads the whole I saw some some Reddit deal with some woman got $10,000 because there was like a 10 page like one of those weird contracts for like a nothing that you're supposed to sign like, like an iTunes agreement or something. Yeah. And there was a little tiny fine print in the bottom. If you're the type of person that's reading this fine print and you send us an email and you're the first person to do it will send you $10,000 they send it $10,000 so if you're actually still listening after all that nerdy stuff that I just talked about, we can't send any money..Be the first one in the subject line to write the word butyrate spelled correctly and you will get a free altran to bottle and CBD of your choice.Butyrate so the first person to send in an email to.. no they have to download the book.Yeah download download the book. Yeah, they have to download the book title the book and then reply with a type butyrate Yeah, type butyrate just spell it correctly. Look it up and send it to us. It'd be awesome. You be the first one you get a free Dr. Brown's signature package. Let us know if you want sentiment or naturalDoes that mean I sign the box of Atrantil that the signature package So much extra stuff you want to do its not going to work out? Thank you so much like and share like and share. Remember, this show isn't intended to treat or diagnose. If you have a health issue, be sure you go and check it out with your physician. We will see you at Episode 34 coming soon. Thank you.Transcribed by https://otter.ai

EP 36 | Ask a Doctor: The Latest IBS, Methane, and Hydrogen Sulfide Research + All Your Other SIBO Questions Answered with Dr. Mark Pimentel

SIBO Made Simple

Play Episode Listen Later Feb 19, 2020 50:53

It’s the season 3 finale Q&A episode! And I have a dream guest here with me to answer all your lingering SIBO queries: the king of SIBO himself, Dr. Mark Pimentel. If you’ve already been down the SIBO rabbit hole, Dr. Pimentel likely needs no introduction. He’s the director of The Pimentel Lab at Cedars-Sinai in Los Angeles, where he researches many pieces of the IBS puzzle, including gastrointestinal motility and bacterial overgrowths. He’s published dozens of studies on these subjects, and it’s fair to say that much of the data-backed information we’ve covered in the first 3 seasons of this podcast, has been discovered through Dr. Pimentel’s work. There were a few recurring macro themes to your questions, so in today’s episode, we’re going to focus on Post-Infectious IBS, Methane overgrowth, and Hydrogen Sulfide SIBO. If you don’t hear your question, don’t stress—there’s a big possibility I’ve covered it in a past episode already. Those who are new here might want to backtrack and listen to season 1, where we cover a lot of SIBO 101 topics related to the aftermath of a diagnosis. The podcast will be on hiatus until the fall while I focus on putting the finishing touches on the SIBO Made Simple book (!!). In the meantime, stay in touch via instagram (I’m @phoebelapine) and by subscribing to my newsletter. Of course, subscribing to the podcast is the best way to be sure you’ll know when new episode start airing again. A quick taste of what we’ll cover: The proper definition of IBS, Post-Infectious IBS and SIBO Why the IBS Smart Test is useful and how to decide when to use it versus a lactulose SIBO breath test How long it takes for Post-Infectious IBS antibodies to be cleared from the body Precautions those diagnosed need to take when traveling abroad Advice for methane SIBO and constipation sufferers and the latest research about what a different beast it is Atrantil as a treatment for methane SIBO What percentage of people with SIBO have Hydrogen Sulfide and treatment plans And so much more... Resources, mentions and notes: Dr. Pimentel's website EP 27 | Bad Bacteria: Food Poisoning and Post-Infectious IBS Talley Meta-Analysis on SIBO in IBS Dr. Pimentel's new paper on IMO: Intestinal Methanogen Overgrowth SYN-010 Clinical Trial for Methane SIBO / IBS-C Atrantil - Digestive Support for Methane SIBO Phoebe’s book, The Wellness Project, on her journey with Hashimoto’s Join the SIBO Made Simple Facebook Community Page Subscribe to the newsletter (and receive a free low FODMAP cookbook) This episode is brought to you by 4 Weeks to Wellness, my online program for finding the sweet spot between health and hedonism. Need 4-weeks worth of easy low FODMAP recipes with a step-by-step meal plan laid out for you? You’ll receive a 20-recipe cookbook, complete with shopping lists, elimination diet guidance and reintroduction worksheets, in addition to the many other program resources like my symptom and activity tracker, lymphatic massage videos, doable desk stretches, and so much more. The 300+ people who have joined the tribe have reported clearer skin, calmer tummies, less bloat, tamer food cravings, and a general ease over their newfound habits. To find out more details about when the next session starts, click here. Use the code SIBOMADESIMPLE at checkout for $40 off! Disclaimer: The information in this podcast does not provide medical advice, professional diagnosis, opinion, or treatment. The information discussed is for educational purposes only and is not a substitute for medical or professional care.

All Disease Begins in the Gut with Dr. Ken Brown

Scheer Madness

Play Episode Listen Later Feb 17, 2020 57:59

Dr. Ken Brown received his medical degree from the University of Nebraska Medical School, and completed his fellowship in gastroenterology in San Antonio, Texas. He is a board certified gastroenterologist and has been in practice for over 15 years with a clinical focus on inflammatory bowel disease and irritable bowel syndrome. Dr. Brown mission is to bridge the gap between medical & natural science. For over a decade he has been conducting clinical research for various pharmacologic companies and he recognized an unmet need for something natural that could help his IBS patients find real relief. After developing the only all-natural & clinically proven answer for IBS & bloating for over 6 years, ATRANTIL (ahh-tron-teel) launched in the summer of 2015. Dr. Brown has also clinically tested CBD in addition to Atrantil to help his patients find relief from inflammation in a safe and affordable manner.He is helping others improve their health on his podcast called The Gut Check Project with his Co Host Eric Rieger. With the ultimate goal of not just improving lifespan, but improving healthspan. On Today's Episode of Scheer Madness, Dr. Bown and I discuss:How SIBO contributes to IBS and functional gut disordersA functional approach to IBS and addressing the root causeThe root cause of all disease and how we can combat itHow Atrantil and CBD help with gut microbiome diversity and IBSThe role polyphenols play in overall healthGut-brain connection and how the gut influences our mood and neurological function(see links for product info)

university texas disease cbd san antonio ibs bown ken brown atrantil how sibo

Crohn's: Living Life to the Fullest

Play Episode Listen Later Feb 13, 2020 61:46

Although Dr Brown is a real doctor, the Gut Check project is here to inform, discuss and most of all have fun. The show is not intended to diagnose or treat anything. So if you have a new mole, grew and extra toe, and cant figure out that weird rash, we recommend that you go get checked out by your healthcare provider. So sit back , free your mind, and get ready to think and step into the gut check project.Eric Rieger Alright guys, here the gut check project. It is now Episode 32. We have an incredible show today if you've ever suffered from ulcerative colitis, Crohn's disease, or anybody that you know has ever dealt with an IBD and inflammatory bowel Disease this show is going to be incredible. We have a special guest today and let's knock off a couple of our sponsors for today we have Atrantil, you can get your own Atrantil at lovemytummy.com chock full of all natural polyphenols you will not find a more comprehensive natural collection of polyphenols to address your bloating, your IBS symptoms etc Dr. Brown you know a little bit about Atrantil.Ken Brown I know a little bit about it and you know what I want to do to offer everybody you said lovemytummy.com I'm going to add a little something if you want your beneficial policy and also we're going to get into that with inflammatory bowel disease Crohn's ulcerative colitis, just put /KBMD you'll save some money.Eric Rieger Save some money go to love my tummy calm /KBMD Dr. Brown is exactly right. Treat yourself treat your gut treat your life Atrantil your bloating relief, it's what they do. Second thing of course here at KBMD health we have the gut check project at KBMD health we also have KBMD CBD and you can go to KBMD health.com and find your own physician vetted co2 all natural extracted, coa of everything that comes out and basically anything that you want out of a CBD we've got Dr. Brown Ken Brown Well the thing is is that everybody's kind of buzzing about CBD and I know even the Crohn's and colitis community people are talking about it but it's been studies have shown that over 80% of the CBD that people grab, don't have anything that is actually on the label. And what that means is you don't really take anything or you could be taking olive oil or whatever. Time and time again today today we treated people this morning and they said wow, I was on like three different CBDs and when we started the kBm the health CBD I'm actually noticing somethingEric Rieger Happens all the time. So if you want reputable CBD, used clinically by gastroenterologist, check out KBMDhealth.com. Get your own CBD today and use code GCP to save 20% on your purchase Ken Brown 20% Eric Rieger 20% Next, our final sponsor of today's show is going to be unrefined bakery. If you want to get gluten free keto friendly paleo vegan, they've got it if you've ever wondered I need to adhere to a special diet and I'm afraid that the food's gonna taste bad guess what unrefined bakery makes great food get just so happens to fit your special dietKen Brown You know it's nuts every patient that we had this morningEric Rieger Yeah Ken Brown Knows of Ann & Taylor Eric Rieger They definitely do Ken Brown They love them like these like they are true celebrities watch that episode. It is awesome unrefined bakery, gluten free. They can do all the other stuff just watch a show it's it's fun Eric Rieger Based here in the Dallas Fort Worth area you do not have to live here to get your own unrefined bakery goods. You can actually go to unrefinedbakery.com use code gut check, and you can have yourself some 20% off I believe on your first order and then right 20% off anyhow unrefined bakery. com use code Check, save some money on your first order. So make it a big one,Ken Brown One impromptu sponsor.. and just keep watching the rest of the show to figure out why.Eric Rieger YesKen Brown If you are a reader and you enjoy novels, go look at a book called in the end written by Dr. Michael Weisberg. In the end. He is an honorary sponsor of this show and for reasons that you will soon see later on.Eric Rieger Yes, absolutely. As I hinted at before we got to the sponsors. This is a dedicated show to ulcerative colitis and Crohn's. And we're going to be visiting with a special someone who will tell us a little bit about her story, her journey, hopefully to relate to anybody that either yourself or a loved one on what it's like to face these kinds of challenges, but Weisberg is a fantastic supporter of the ulcerative colitis and Crohn's foundation. He knows a lot and he's, it's awesome. And he has a book like that available. So ..Ken Brown In the end Eric Rieger In the endKen Brown Honorary sponsor.Eric Rieger All right, let's start The project. So now we just wait a little bit and then we're just gonna start talking. And I don't want to mispronounce your last name. Okay. Okay. eyeball 321Eric Rieger All right, we are here on the gut check project. It is now episode number 32. I am here today with your normal host, Dr. Kenneth Brown, and we've got a special guest. Paneez Kahkpour. Oh, you know what we had her and now she can talk.Paneez Kahkpour Am I back? Hello Everyone. Nice to see y'all.Ken Brown Well Paneez has been my patient for over 12 years. What do we have 14 something like that.Eric Rieger Awesome. Thank you so much for coming Dr. Brown. You have a monikor for her already that you just annoyed her with. What is that?Paneez Kahkpour 12-13Ken Brown Something like that I've always referred to her as the Persian princess. And so she is the she's Dallas's own Persian princess to the end here to the Persian community. This represents you My life the Persian princess. So sweet. She went to Iran of what about three years ago and brought me back a hand painted? What was that? It was art, but it told a story.Paneez Kahkpour Yeah, it was. I'm trying to remember what it was. I'm pretty sure it was. Maybe it's like an old fairy tale. It's like a couple. I think it's called Laylee Imagine. I think it's their story, and it's the picture of them.Ken Brown Wow. So.. really beautiful. I took a picture of it and send it to my friend Reza, who's who's a gastroenterologist in Florida, whose Persian also and he goes that's that's really expensive. Be very careful with it was like,Oh, okay. Eric Rieger You're hanging out the window of your car.Ken Brown Using it as a fly swatterEric Rieger Trying to direct traffic in Denver. Ken Brown Yeah I was. Let's go over here. These Atrantil ads Don't stick on it at all.Eric Rieger So you've had Crohn's Correct, yes. For how long? Paneez Kahkpour 16 yearsEric Rieger 16 years, you've been a Crohn's patient. And today, I think that what we really want to do is get your perspective on what it was like to be diagnosed to learn about what it was. What led you to go seek help in the first place? So back at the clock a little bit. And what did you first experience that drove you to go? In fact, you didn't go to Ken first you went to another gasterologist.Paneez Kahkpour I was. I saw pediatric gi doctor in the beginning, I was 15 at the time, all right. Yeah, I just had all the symptoms. I couldn't eat anything anymore. I was just constantly going to the restroom. And every time I went to a doctor or you know, General doctor, they said I had the flu. They'd give me antibiotics. Send me on my way. A couple days later, I'd be feeling terrible again. And that lasted several months. I went to the ER multiple times to get IVs, but nothing seemed to help. It was it wasn't until it was probably my like sixth or seventh ER visit and my grandma was like, You're not going anywhere you need to stay here. Someone needs to see you. I called an old pediatrician of mine. His name was Dr. Shams and he ended up. I gave him the symptoms over the phone and he said, I think I know what you may have. Let me call in a specialist. I was hospitalized at medical city Plano and then did a colonoscopy. And here we are. Eric Rieger lLet me ask you. So you said you're 15 .. So freshman high school.Paneez Kahkpour I yeah, I that would be freshmenEric Rieger So as a freshman in high school going through this, I mean, your peers that age adolescence, what is it like trying to navigate that you internally you already know that you don't feel normal? So what were you having to do to?Paneez Kahkpour I wasn't ever eating lunch. I you know, everyone thought Something's wrong with her because she's not eating. And at that time, you know, it's something super embarrassing. You don't know what's happening with you. And so it's not something I really talked about. Just because I, I didn't know it was happening, and I didn't have anyone to really talk to at the time. And it wasn't until I was diagnosed. You know, when someone finds out you have something they know a friend of a friend. And I ended up speaking to a girl who was also someone who has Crohn's disease, and she really helped guide me kind of through the initial process of everything, and it was very, very helpful.Eric Rieger Wow. So when once you found her and so at this point, you probably found her after you've been officially diagnosed. Yes, correct. Yes. So what was it like? I mean that it doesn't sound like it, looking back 16 years, but there's probably at the time seemed like an eternity of not knowing Paneez Kahkpour Oh, yeah. Eric Rieger So what was that like?Unknown Speaker And it was, it was very hard. You know, when you're young, all your friends are doing all these fun extracurricular activities and you just don't have the energy Because I just, you know, was constantly sick. It was very difficult, and very, very lonely. Even though I had someone who had some experience, it was still it was just that one person who wasn't who didn't even live here. So it was pretty difficult. Ken Brown You said a word right there that I think this resonates with a lot of my patients, you felt very lonely. The Psychology of a disease like this is unimaginable for you. And for your loved ones. Would you just describe the loneliness a little bit? Paneez Kahkpour You know your entire family, the ones who know and who really understand are there for you, but I mean, they only know so much. They can only help so much because they can only empathize to a certain degree. And so, you know, when you just don't have anyone to talk to it feels really difficult to try to even begin like know where to begin and who were to go who to talk to, but I was able to find some people And find my way through the Crohn's and colitis foundation that took me a few years to even find I had no idea about it. No one told me anything. Ken Brown Why did it take so long to find the Crohn's or colitis foundation?Paneez Kahkpour You know, I just don't know if it was back then it was still something super new, you know, no one really talked about it, it. It's even still now it there's a stigma. It's, it's embarrassing. It's gross. So no one really talks about it. But it took me several years until I knew that there was such a thing as the Crohn's and colitis foundation. But after it took me a lot of googling, lots of lots of googling until I was able to find it.Eric Rieger So but leading up to that you you get this diagnosis and as you're trying to educate yourself and you haven't found the foundation yet. What type of changes did your pediatric gastroenterologist ask for you to make? What were you? Did you have difficulty with compliance? What was it like to step out of there and say I've got this diagnosis and now kind of have an idea of what I'm going to do. What How'd you handle that?Paneez Kahkpour I mean, it was hard. You're 15 and you, you know, don't, you're not usually on some type of regimen. You just kind of live your life as normal as can be. But when with this change, I was taking 15 pills a day, when I was barely even taking a Tylenol before that, you know, I struggled taking pills. And then yeah, he just told me I had to, you know, watch what I eat, see what my triggers are. Beyond this, you know, diet of pills, you know, it's pretty much I was what I was consuming and so my entire day was spent taking medication and so I didn't really have time to have friends really go out and do anything because I was at home taking medication or going to bed.Ken Brown I it's it's weird because I smile when you say this because I've seen you progress over these years and become this and tremendous advocate, super. I mean, healthy you you radiate this energy right now. And that is to bring so much hope to a parent that has a child who was recently diagnosed. And that's what I want this episode to be about your story. What I love hearing the questions that Eric is asking you are the wait a minute What is this because as a gastroenterologist, and this is probably what you experienced, it's like, Look, this is your disease. It's either 5% no seniors all sort of, these are our options. Where do we go from here? He's asking life questions. He has an 18 year old and a 16 year old. Yeah, it's Max 16 Eric Rieger Eh two weeksKen Brown Two weeks Okay, it's getting real close. So he's asking it as a parent Yeah, well what happened this and that. I'm listening to this and I'm like, I asked it as a clinician. So I always keep going, I love I love where you go with this.I love it love it Paneez Kahkpour It took me many years to get here. It was definitely a bumpy road and I had lots of highs high and low moments. But you know, right now I consider it being a really high moment. I feel good. I'm in a good place. But you know, with all the struggles goals and all the things I had to get through with, you know, taking medication every day having to be doing IVs every six weeks like that was insane like, what 15 year old does that you know like that's it was a whole new territory. Eric Rieger So making a change. You talked about that he said, watch what you eat and pay attention to your triggers. My wife was recently diagnosed with celiac disease and for her there's, there's an interface, right? We used to enjoy just sipping on a cold beer every now and then that and that's gone. So that's not the end of the world. But the changes obviously for her are more stark when you family gets together or you want to go on a road trip. There's just certain things that were cut out what was it like to you to discover? These are my trigger foods? These are the things I can't do. I've got my circle of friends that may or may not fully understand what I'm dealing with. How did you integrate back to I've got at some point you're gonna get a crossroads I gotta get my social life back in.Paneez Kahkpour Right. Eric Rieger So what did you do?Paneez Kahkpour Well, first I educated all my friends. That's the big step because if they don't know what you're going through, if they don't understand what the disease is and they have Zero empathy for you. They don't really understand Ken Brown What did you say to them?Paneez Kahkpour Well, I have Crohn's disease and they look at me guys go cross, like what is that? I'm like, well, you know, it's a digestive disease. I try to use words as simple as I can for them to understand. I'm like, basically, I can't eat lots of things because my body rejects it. And half the time I say, if you want to know more, just go Google it because I don't want to get into the nitty gritty, all the things I just go look it up. But that that helped. And then finding out which friends were, you know, there for you and which friends were not that was really helpful. And then with diet changes, and just lifestyle changes, I had to I learned that had to be present for the things that could be present for and if I couldn't, then I had to listen to my body and say no, and really just crossing my fingers and hoping that my my friends would be empathetic to thatEric Rieger So for Paneez. Think about the ones Small advantage that she did have was turning her friends to Google. Because think of someone just a decade before that having this type of disease trying to share that experience with their new diagnosis with their friends, like, go to the library and look whatever up if you can. And thats just not going to happen.Ken Brown As an adult doctor, I have the advantage of sitting down with somebody that has either been handed off to me by our pediatric doctors .. had has some incredible ones in that Whitney Kendall Brown, john Baker, jack and they've got incredible doctors. So I get the pre prepared family. And now at this stage of my career, my patients are their, their children are starting to show up we're seeing more of this disease. So when I said you have what did you say because I don't know how much to vomit on somebody. Paneez Kahkpour Yeah. Ken Brown And well, quite honestly, when I met you when you came into the hospital as a flare And the only thing I was thinking back on my Paneez on and she'd been my patient for a long time. And you're an incredible patient, you do everything that you're that you're supposed to do, and you're an advocate, we're going to get into all of that about how you've been giving back, and how important people like you are coming on the show and doing this and being part of the Crohns Colitis society. I remember one thing I remember your mom crying. That's all I remember about the whole impatient experience, because it was too much. Eric Rieger Well, maybe, maybe she maybe your mom was curious about the challenges it was going to be to you. And I'm going to ask you about that in a second. But the second, the second thing I was kind of curious about that may lead into why her mom would would cry because I think that that's anybody cares for the kids going to be upset. But what was it that the physician said would happen? If you didn't make these appropriate changes? And know what, what did you begin to learn the risks would be if you didn't become a compliant patient, because at some point, for some patients, it doesn't matter. They just kind of like I don't really care. I'm just gonna keep living and yeah suffer the consequences. That's not the route that you took. So what did you hear that made you decide? I'm gonna do this.Paneez Kahkpour It was mainly how I felt. I didn't want to feel terrible anymore. I was very tired. I was sick and tired of being sick and tired. You know, that's what I remember telling myself when I was really young, as I'm tired of feeling this way. And my doctors at the time, they just said, Listen, if you're not going to do this, you're not going to get better. You're just going to get worse. You're going to have to have surgeries, you're going to have to do all these other things. And mainly, the surgery is what really scared me. Especially being so young, because most people don't have to go through that stuff. But it was mainly just really not wanting to feel that way anymore. And I must say there was a period of my time where I wasn't compliant. And that's when I met you. And that was really what changed everything for me is because a doctor changed my medication. And I didn't really take it because it was a pill. I was on IV before and then it changed. And I got super sick and I was in the big, big flares when I met you. And after that, I was like, I never want to feel like this again, like it was not worth it.Eric Rieger Was the risk of a collective mean or anything else like that kind of on your radar? Did you think that that might ever happened to you? Paneez Kahkpour Thats always in there like the backburner. I always think that like in the back of my mind, like there's always a chance for all of that. Eric Rieger Sure.Ken Brown Yeah. So let's, for everybody else that's listening this not familiar that. I mean, our audience is getting pretty broad right now. And for those people that don't know what Crohn's is, that's why I wanted to say, what did you tell your friends what Crohn's is? And you said, I couldn't eat certain things. Paneez Kahkpour Right. Ken Brown Let me rephrase it now that you're, you've had it for a few years. What would you tell people what Crohn's is?Paneez Kahkpour I would just say it's a digestive disease is an autoimmune disease. And so basically, my body doesn't know what's happening. So it's attacking itself. And with that comes all these terrible side effects.Eric Rieger Yeah. Ken Brown That pretty much sums it up. Eric Rieger Yeah, definitely. Ken Brown That is beautiful, everybody Makes it too complex that So you went from. I'm talking so what you are gifted with is the ability to understand what your peer will will will hear which is I can't say automated. I can't say all this. I'm just going to say what I struggle with as a doctor is how much do you want to hear about this? Right? So when you were 15, you said like, the bottom line is I just can't eat certain things, and I may get sick. Now you're like, Look, here's the deal. Yeah, my body's attacking my own intestines. That's what Crohn's is. We're gonna leave it at that.Eric Rieger Yeah, definitely. So do you want to get into to mom? Because this is something that just for the audience, this is something before you even got here Paneez that came was like, the thing I never forgot is how resilient Paneez was and how much your mom apparently and I've never met her but was concerned about your future.Ken Brown So we each every single episode regrow and we we find new ways we find new science and I become a better doctor because of it. I mean Eric sees the patients he puts them all to sleep. And when I asked you to come on the show is because of the emotional aspect of being a parent. It wasn't so much that you because you're amazing. I mean, like you persevered and we're going to get to the Oasis camp where you've been a counselor, we're going to get to the fact that you're a speech pathologist for underprivileged autistic kids with so you are up here. I just always thought, did your mom know you were going to do that when you were diagnosed? Paneez Kahkpour You know? I don't think so. I mean, you have all the hopes but there was a time where the disease was all that I was and that very much defined defined me and my life. And I think that was a big struggle for her. Because you never want to see your child sick and in a hospital bed with hooked up to all these wires and IVs. And that's just a terrible site. She struggled a lot. My entire family did. My grandmother, my brother, my dad, but a lot my mom because she was my main caretaker, she was there for every step of the way. But I don't think she ever thought that I'd be doing all these great things and being, you know, self sufficient.Ken Brown It's a story of perseverance. It's a story of giving back. It's a story of sharing and caring and doing this kind of thing. It's so we were at the Crohn's and colitis annual gala, where my partner, Dr. Mike Weisberg was being honored as Person of the Year and gave an incredible touching speech, or keynote speech, I should say, where I thought it was just I mean, I admire public speaking, because just like you're doing right now, being on a mic is not so easy sometimes, but you're crushing it.Eric Rieger Well, not only is he a gastroenterologist, didn't he? Didn't you tell me once before that his one of his kiddos has RBD of some kind?Ken Brown Yes. So leading it up to this, and I want to ask a favor of you Paneez because it's going to take a few minutes. So I actually called Dr. Weisberg Dr. Mike winesburg last night and I said, Hey, I'm gonna bring a Crohn's patient on and I know that your son had Crohn's because you discussed it in your keynote speech. And I'll tell you what, I've worked with him for 17 years, and I had no idea this was going on. And so it was like, it's like the duck with the, with the flippers, right? You got to keep your game face on go to work, just like you've probably done a million times. Yep. You feel like, you know what, and you're Paneez Kahkpour Pushing through Ken Brown Push through. I got to tell you that. I'm just a quick side note, before we get back to that really quick. Crohn's patients. I have to tell them that they're sick. They're like, No, no, no, I'm good. I've been worse, i've been worse. They're tough as nails like Crohn's people just like at some point, they just start sucking it up and they're like, No, I'm just gonna deal. Screw you. I'm not I feel sick, but I'm sick of being sick.Paneez Kahkpour Yeah, you've done that to me. Actually, beforeKen Brown I have. I keep trying to make her sicker than what she is. I'm like your bloodwork.Paneez Kahkpour I know I remember one time I was I was very, is during my second flare and I came in to see you. You had my bloodwork and I was, you know, I dressed up for the day trying to make myself feel good. You know, if you look good, you feel good type of thing. And you made me walk to the emergency to the hospital and it put a gown on because you're like, you're very sick. I didn't know it because I was like, I'm fine. I'm strong. I got this. And I wasn't.Ken Brown So when I called Mike last night, I was I just wanted like, hey, what was it like being the parent of Crohn's patient and so as it so happens, Dr. Weisberg, whom I admire very much, he's been my partner for years he was awarded Person of the Year for the Crohn's and colitis society. He is also an award winning author of two novels, the hospitalist and in the end that we discussed as an honorary and rather than just sit there and throw, you know, two lines Oh, it's it's tough being a parent of a..wrote a little bit and if you guys would humor me, give me just about five minutes. This experience is something that I want every parent to share. If you have a sick kid, I would like people to realize, because what he showed here and he just wrote this in an email, and I read it this morning and I went, holy cow, so you wrote it last night. So I'm going to read it. And this is from Dr. Weisberg verbatim no changes Eric Rieger All right.Ken Brown When I think back 13 years to when my son Reed was diagnosed with Crohn's disease, my mind flooded with vivid scenes and emotions. I will try to relate some of them to you in the next few minutes. Reed had never been a very active child. He was never one to ask to go out to play football or ride his bike. We just assumed that he was a laid back kid, a cerebral kid who enjoyed playing on the computer and playing video games more. At age 12. We decided To send him to sleepaway camp, which is not Oasis, a traditional camp sleepaway camp for a month over the summer, along with his nine year old brother Brent, in order to go, Reed had to have a camp physical, which my wife and I thought was routine. I was working that night when my wife called me and told me that the physical exam revealed that Reed hadn't grown an inch in the past year, and had actually lost two pounds. Plus bloodwork showed that he was severely anemic. I felt guilty that I had not thought of this as a cause of Reeds easy fatigue ability and avoidance of strenuous activity. But as I thought about it more I realized that night that Reed may have Crohn's disease. I had suffered from a related disease called Iritis, which is Crohn's disease of the eyes. And my sister had been diagnosed with Crohn's several years before. I knew that chromes presented and reads it Group and that all his symptoms fit this diagnosis at 730. That night I drove frantically to the pediatricians office wanting answers and I pounded on the doors of the locked offices for 20 minutes until I realized that it was futile. Since I was a gastroenterologist treating Crohn's patients, I knew what a devastating disease it was. And I became terrified. When I got home that night, I personally examine Reed and found that he had an anal fissure, which he hadn't told anyone. He'd been having rectal bleeding read younger brother went to summer camp alone that summer because Reed was too sick to go. My wife was too upset to drive Brent to the airport, so she stayed at home with read while I drove Brent and dodged all the other parents questions about why Reed wasn't going. I met my wife in a park in between our home and office one day at lunchtime, and we just sat talked, held hands and cried. We had no idea how extensive and severe Reed's disease was. But as his parents, we felt so sad for him and what he had been going through and what the future would entail. I personally felt tremendous guilt. I felt that I had given my son this disease and it was my fault that he was sick. I talked to my wife and several friends who told me that if I took all the blame for Reed's illness that I must also take all the credit for his admirable traits, such as his intelligence, his sense of humor, and his willingness to work hard to achieve things. For a very long time. These arguments did nothing to assuage my guilt, and it was only after Reed felt better that I quit being so hard on myself. We took Reed gastroenterologist who did his colonoscopy while I stood in the endoscopy room watching, I saw all the damage the Crohns said done to Reed's intestines on the telly Vision screen as a scope made its way around the colon. Afterwards, I had to go to work and even though I felt depressed and upset and guilty, I never missed a day of work or miss treating a patient due to my grief. Reed was started on enamoran and we waited for him to get better.Ken Brown Instead of getting better Reed worsened and he had more fatigue and high fevers his liver test went through the roof the Emoran was stopped just as we left for a family reunion on Amelia Island in Florida. I talked to his gastroenterologist the night before we left and he told me it was okay for Reed to go, but to take him to the hospital first for two sets of blood cultures. I drove Reed at tea at 10pm to my hospital and had blood cultures done. The trip to Amelia Island was a disaster. Reed was sick had high fevers the whole time, and I finally found a doctor in the box where they were willing to give him some antibiotics. Reed love to fish but the day of our deep sea fishing trip he was sick the entire time he lay in the boats cabin and vomited into a pail where he lay. I could go on with memories forever overall, until we took read to see Marla Dubinsky and IBD expert Los Angeles. He was constantly sick with pain, fever, diarrhea and anemia. Marla did testing put them on Remicade, which he took for six months until developing an anaphylactic reaction. I was scoping at the time that he had this in the same building I was so I had to run and see my son go through an anaphylaxis reaction. I had Remicade stopped and Dr. Dubinsky switched into humera, which he was on along with methotrexate for 12 years. He stopped the methotrexate last year and is now only on humera shots every two weeks. It was hard giving my son a shot every two weeks, but he was so brave and never once complained. I could tell you that I felt depressed devastated and guilty, and that the light in my life had been turned off. That is until Reed started getting better. Boy did he ever he started to grow and gain weight started having a physique that resembled his classmates instead of a skeleton. He went into remission grew to a normal height and weight. This summer he will graduate from medical school and start a residency in internal medicine. I am extremely proud of all he has accomplished but even more proud of the person he is. He never complained, never cried why me, but instead has met each challenge head on, and fought until he won. When I asked him why he wanted to be a doctor. He told me that he wanted to be like me and help make people better. He wanted to be a healer. The light in my life is back on and I am certain that I will be alive the day, a cure for the diseases is found an impromptu thought by Dr. Michael Weisberg when I just said What's it like being the parent of a Crohn's kid? Eric Rieger What why so short? Why no detail?Ken Brown There's a reason why his books are so good.Eric Rieger Now seriously, Dr. Weisberg, thank you so much for the submission that's it that's an incredible story. Paneez Kahkpour Yeah. Eric Rieger How do you think your your mom would relate to that?Paneez Kahkpour 100% like the feeling of guilt I think that my mom and my father felt that for many years and I still think they sometimes do still to this day you know, I don't think that ever really goes away. But yeah, the the guilt the depression just feeling helpless that you can't do anything for your child.Eric Rieger Did your parents have to watch you try like we've seen a lot of Crohn's patients do the the drug hopping from Enamoran to Remicade to humera etc. Till you finally found some mix. It works for you and then I mean, did you did you have to endure anything like that?Paneez Kahkpour Well, luckily, no, not really. I was on a bunch of like I was on Enamoran and all these other things when I was first diagnosed, but I was also started on Remicade, and I've pretty much been on Remicade ever since I took a year off, and that's when I met Dr. Brown because I wasn't complying with the medication I was taking, but I've been able to go back and Remicade and that's pretty much all I've ever really been on. Luckily, knock on wood.Ken Brown One of the coolest things here is in we forget we take the burden of everything but the fact that Dr. Weisberg noted that his friends and family and his wife said, hey, there's a lot of great traits. There's a lot of great traits do. I mean, it's so hard as a parent to go I mean, except for Eric every time Gage scores, thats my son. That's me out there.Ken Brown But it's so funny because his parents, that's what we do as parents is we just say What did I do wrong? How could I have changed something Because my child may be sick and I don't think it stops at Crohn's or colitis I think it you know anything juvenile rheumatoid arthritis. I don't want to get into the, you know the cancers and things like that everybody says what could I have done different and it was fascinating to think that it's exactly right the same characteristics that Reed, developed, or at least had all along allowed him to now he's gonna be a bass doctor, a real badass doctor, and I've met him and he's taller than me. I mean, he's a stud.Eric Rieger I live vicariously through everyone I know.Eric Rieger Nice.Ken Brown Yeah, you met him at the Crohn's and colitis foundation didn't?Paneez Kahkpour actually knew him through camp Oasis actually.Ken Brown Oh, we need what is camp Oasis says,Paneez Kahkpour Well, Camp Oasis is a camp for kids with IBD Crohn's disease or ulcerative colitis to come for about a week to just live like a normal kid and have fun at camp. It's probably the best thing I do in my life every year. I've been going for I think about seven years are so best time of my life.Ken Brown I thought your doctor visits for me with the best thing?Paneez Kahkpour No, Yeah, that's it. That's like neck and neck.Eric Rieger So, Camp Oasis, if I remember correctly, there are 12 states that have a location that routinely host these kiddos with you see your Crohns. And then I think the one here in Texas is what outside of Bruceville?Unknown Speaker Yeah, now it's, um, it wasn't Bruceville and now it's some place called. I'm not sure. You know, Texas, so many little town. Sure. Not really sure. But yeah, it's some it's like two hours outside of Dallas.Eric Rieger Okay, nice. Yeah. And so, but it's directly affiliated with the Crohn's and colitis Foundation, correct? Paneez Kahkpour Yes. Eric Rieger And so, supporting the camp oasis. It's, you're going to have the latest research, the latest techniques, the the best, quote, unquote, training for a kiddo to learn how to deal with the situation right?Paneez Kahkpour Well, you know, they have it's basically a week where They can feel like they are heard or noticed. They have other friends there who also have the same disease they have right. And most of the counselors who are there, not all of them but most of them also have IBD. And so it's just like everything you could possibly want in life and a week.Ken Brown So somebody feels comfortable. They say my belly hurts that's..Paneez Kahkpour Oh, yeah, we have a whole med staff everything like you were mentioning we have we have a whole med staff nurses, child life specialists that called everything every everything they would possibly need. They have theirEric Rieger So would you say by attending a camp like that having this disease affliction that you began to learn? I can have a normal life.Paneez Kahkpour YeahEric Rieger These people are making it or I remember when I felt like that you probably serve as a mentor if you just happen to be further along than somebody.Paneez Kahkpour Definitely. I mean, I feel I wish I went to camp as a kid. But I didn't so I'm lucky to be able to go as an adult. But yeah, they they see all these adults doing all these wonderful things like Reed going to medical school, and they see Oh, I can do that if they can do And they have the same disease I have, and they have had surgery, they've done all the things I've done, I can do the same thing. And its wonderful.Ken Brown What was your first year like as a counselor, because it had to bring back a lot of memories of what you experienced.Unknown Speaker I mean, it was, it was sad, in a sense, because you just see all these kids, like, I don't remember myself, you know, as a child, like dealing with all these things. We just see them and you just see how strong they are and how happy they are and how they, like you say they persevere. And I'm like, how even though I was the same, but I just, you see, and you're like, it's incredible. And every year I go I cry because some kid says something super motivating and inspirational. I'm like, I don't know if I'm doing anything for you. Because you're the one helping me like feel like I'm there to live a better life. It's all it's all them. It's really wonderful. But yeah, the first year was intimidating. I didn't know anyone. I'm meeting all these people with Crohn's and colitis, like that's super cool. But at the end of the day, you you leave with a family and we've all been together ever since.Eric Rieger That is awesome. How many times have we heard things on this show with from guests that giving is the best getting that you can do? Ken Brown Absolutely. Eric Rieger I mean, it really is. Ken Brown Absolutely. When I'm curious as there's a doctor, you said that there's a doctor that runs this every year?Paneez Kahkpour Well, yeah. So it's, it's the Crohns and Colitis foundation sets it up, and then they have a pediatric doctor come along, just because if there's a flare if a child needs medication, we they handle all the medicine, everything. They they do it all and yeah, there's a pediatric gi who comes along and does everything.Ken Brown Just the whole idea of just being a normal kid, and still experiencing your normal symptoms. And it's not like blown out of proportion. It's not like overreact. It's like Okay, come on over here. Let's go over. Yeah, you're not going home. We're gonna we're gonna make you feel better. Paneez Kahkpour YeahKen Brown That's cool.Eric Rieger Absolutely. And you can I noticed on the website, that Most people can volunteer if they wish to. And you can donate, obviously, directly to the camp through the Crohn's and colitis foundation. So it's obviously an incredible resource for people who are young and newly diagnosed.Ken Brown I'm going to put you on the spot. But it was there ever a time that you ever were this I'm really put you on the spot because because I think it's like a healthcare provider if I'm in a camp with people that potentially can get sick on me, you know, I'm like, worst case scenario person. So were you ever in a position where you felt that you were worried for somebody?Paneez Kahkpour Um, yes and no, yes. Because they weren't feeling well, or they, you know, have been vomiting a lot or something, you know, because a lot, it's in the summer. So, there's a lot of heat. But no, because we haven't fully staffed with all these smart doctors and nurses who come and help the kids. So like, there was never a time where you're like, Oh, this is not going to be good because they're fine. They're in safe hands. Ken Brown That's awesome.Eric Rieger That is awesome. Well, what can people do if they wanted to connect with someone from Camp Oasis? And let's say that they have a child that they want to get enrolled, but they may not live close, they're a particular resource or a way for them to get in touch with counselors to do that?Paneez Kahkpour I would say just going to the website would be the best starting point.Ken Brown Crohn's or colitis or the Oasis?..Paneez Kahkpour Because that will take you to the camp, website. And m depending on where you live, you can see where the closest camp is and then I think there's always an email or phone number for the director who like sets up sets it up for every state.Ken Brown Man i'm sitting here thinking I'm just like, wow, it's, it would be really cool for like, I'm hearing this like I learned about Camp Oasis from you. Yeah. And I'm like, Oh, I I feel like like a jerk like I have not been involved sooner than that. And then I went home and talked to my kids lil bit about it. They're just like, Wow, that's great. And I'm sure that there's a lot of different camps for different illnesses.Eric Rieger Oh, yeahKen Brown I didn't realize that there's a lot of people giving back all over.Eric Rieger That brings me. That brings up my next question. I'm glad you brought that up because not that far from here for juvenile diabetics, there's a place called Camp Sweeney. And when people go and that was it, I was a maintenance man there when I was in high school, but..Ken Brown He was the janitor.Paneez Kahkpour Come a far way.Ken Brown She's over here going, Wow, you've come a long way. I had Crohns almost died and I'm doing this but you..Eric Rieger I guess you got out of your truck. But the thing that I found kind of interesting is almost and I'm kind of curious if it's the same for for camp oasis. The first time that someone came to camp Sweeney, sometimes there was a chance. They were reluctant to get out. They didn't really know why they were going. They really didn't know what they were going to get out of it. They kind of had to be talked into it by their parents. And then when they got there You saw it within the first 24 hours. Oh my gosh, these are my These are my people. Yeah, they understand what I'm doing so I guess I'm just saying that for someone who may be new to camp Oasis, you have a kiddo you get them get them inoculated, get into around and to talk to someone.Eric Rieger That's awesome.Well..Paneez Kahkpour Yeah I mean, it's super helpful. I, I, I've seen kids who are newly diagnosed come into camp for the first time crying because they're like, I don't know anything. I don't know anyone. Like I'm super nervous. They leave crying, but not be because they're happy that they met all these friends, and that they're sad to leave, they don't want to leave. And so everyone starts crying. What are they? It's, it's the best. I mean, you know, whoever wants to apply to be a counselor. I think for the Texas camp, it's open. So come hang out. Ken Brown Well, no, we have a whole new topic that I want to get into. Oh, yes, because I've known Paneez the Persian princess for a long time.Eric Rieger This is..Eric has no idea what you know.Ken Brown Yeah. And I've watched Well, she has gone on to not only be a camp Oasis, Counselor, but she's doing something which I think is fascinating. It's huge. And now we're going to talk about something else. That is a passion of mine, which is autism. Eric Rieger Oh, yeah.Ken Brown Yeah.Eric Rieger So I did know that sorry.Ken Brown Well, you give a little background about your education. And now what you're doing because if you want to talk about the one two punch of giving back, Camp Oasis, and wow, that was just the jab. Now we got the right cross coming. This is coolPaneez Kahkpour You know, gotta do a lot. So I actually I went to University of North Texas here in Denton, wonderful school. I studied speech language pathology, pathology, audiology, so I have an undergrad degree in that. So technically, right now, I am a speech pathology assistant, but I'm working on my grad school applications at the moment.Ken Brown You speak better than us. So you're, you're the master in this room.Eric Rieger Thank you. Pretty good.Ken Brown Pretty good. Speak English real good.Paneez Kahkpour You know, lots of practice. But yeah, so I work with most of the kids I work with right now have autism. And it's it's quite a job. It's actually pretty fun.Ken Brown But it's not just autism. It's actually autism for a lot of underprivileged kids. Paneez Kahkpour Yes. for underprivileged kids. Ken Brown Yeah. And so what? So So Penny's and I were talking about this, because autism, I'm a huge advocate of the gut brain access, and that if you heal the gut and you feed the gut, then it will heal the brain and we got into a discussion so you asked all those questions at the beginning of the show. What did your pediatric gastroenterologist do? What did you recommend for diet recommendations? What did he do this and that? So I'm sitting with Paneez in my office and I'm like, Oh, my gosh, that's so cool. Can you get them to go gluten free? Can you get them to go Whole Foods? And she's like, Well, let me tell them my patient population first. Yeah, has described what the typical person lifestyle is and They're, they're home life.Paneez Kahkpour I mean, most of them are lower income. And so with that brings just difficulty and buying just healthier foods, and having access to a lot of stuff. I was talking to a parent actually, who had to take a child to the doctor, and they waited eight hours. So I'm like, they still have access to a lot of things. And so they're not eating as well as they should, or they may not be doing the things that you know, you and I have easy access to. So that's what makes a little bit harder.Ken Brown So, a couple episodes ago, Episode 28, Doug Blonde was on here and I challenged him with the same thing he is in. He's a medical doctor that it's an advocate for whole food plant based. And I said well, the problem with that is is that when you say whole food plant based you think of going to Whole Foods and spending a lot of money. Paneez Kahkpour Yeah. Ken Brown And I and he told me that no, you can do it really cheap and he gave prices he discussed the price of doing lentils versus as long art..My gosh, I can go down rabbit holes on this one, our secret weapon, which we'll reveal one day he sent me some incredible articles on manufactured fibers or fibers that that are added to foods to augment the plant based diet and to do things like that and the inflammatory process that it actually causes. So if you're opening up a package mean just that means that they put stuff in there which will pause an inflammatory reaction in your body. I know that that leads to intestinal inflammation resulting in brain inflammation. So on Doug's episode, we discussed how you can buy for pennies on the dollar foods which will supply thymine, which I mean he's got the vitamins down, he's got the fiber down. So the misconception is that you can actually take a parents say don't go through the drive thru McDonald's, it seems cheap. When if you can just go to the periphery of the grocery store, it's always the periphery. It's not the middle, not the middle. Do not walk down the aisles, just walk around the outside, you'll be able to fill your cart with sustainable foods which provide most of the nutrients that you will need. And you can do it in a cost savings and it, it hurts my feelings that I mean, I feel like you're doing an uphill battle right now camp Oasis is awesome. That is like you crush it right there. Now you're going and you're helping autistic kids that when they go home, probably the parents are not educated enough or Well, nobody is it's America. Nobody's educated enough on how to properly eat.. Well I'm not I'm learning. Eric Rieger Well think about the challenge that you said about the mom who has to wait with the kiddo for eight hours. That's a work day for her. It's a work day for the dad. I mean, they're sitting there doing that they're negotiating. I'm going We are going to have to do without because we have to go and do this. And we're going to waste all day waiting. Ken Brown So let's go back to the parent perspective again. So now you have an autistic child that you are trying to work on their speech capability to express their emotions. And a parent shows up and says we need to pick them up. What's your interaction with the parents?Paneez Kahkpour Um, it's not too much. It's usually like, every time I see their child, it's maybe like a four or five minute conversation. So not a whole bunch just because in that conversations is, this is what we did today. These are the things you should try to do at home and see you next time. That's basically as much as we really get because most of its spent with that child. So it'sa little hard. Ken Brown I could just imagine what happens with somebody who is worried about paying next month's rent. Eric Rieger Oh, yeah. Ken Brown And they have a trial that it has some trouble communicating on the Autism Spectrum Disorder it's the the ability to become empathetic to that situation. You have that ability because you have Crohn's disease, and you have muscle through it and you chose a career which could be one of the more difficult uphill battles to change a the underprivileged autistic community. And I commend you on that. Paneez Kahkpour Thank you.Ken Brown That is awesome. That is it is a bold, bold thing. Definitely, but I could totally see. Man, it's a hierarchy of needs. I have a I have a patient whose they actually corrected their their child's autism but they also have the resources share the intelligence they I mean intelligence, meaning they're both like super educated, and deep dive and didn't stop at the traditional medical thing. And they started looking at all kinds of alternative therapies like hyperbaric oxygen chambers, which then they purchased for their house and they, I mean, stuff that I mean, whenever they come out, I don't know why they even come to see me. I'm just like, so what do you want? What have you read? You're gonna teach me I got several patients like that run like we should probably meet at the coffee shop I learn from you. But..Eric Rieger What's it like to have to have a kiddo who who has a breakthrough after the training, so maybe you have somebody who's been non verbal, and then suddenly they..Paneez Kahkpour It's greatest like every, you know, if someone else looking at it may not seem like a very big change. But from someone who doesn't say anything to like, give me a sound is just incredible. It's, you know, it's those little baby steps that make it a, you know, a big change. And so those baby steps are the big ones. Eric Rieger I'm curious as a parent when they see like this one little victory that helped them kind of buy into the process that Okay, we've got this little victory here. This isn't time wasted, my child's doing better. And maybe they expand their acceptance of things that you're yeaching them to do at home.Paneez Kahkpour Yeah, I mean, I think so to a degree. Yeah, they, especially the ones who, because I do home health as well. So the ones who see are in the sessions or they can hear they're like a, you know, earshot away, they can hear it. I think it's super helpful. Because, you know, they see like, how much time is spent. And then you get that one little like, like, vowel sound, or like, you know, kid thing more or something super simple that we take for granted, because, you know, we never had any issues with that. But yeah, it gives them hope it gives them you know, like a light at the end of the tunnel.Ken Brown So, like I always do when I just think what's going on what's going on at a cellular level, how is this happening and you're dealing with the end product of this which is necessary, which communication is the key, so I've never told you this. But anyways, I grew up I was a really bad stutter. And so my ability to communicate was really limited. Like for the first six, the first six grades, and I was put in remedial classes, because they just assumed that I was stupid. And what I did is rather than stutter I did a type of stuttering called blocking. Right? I could see the word coming. And I'm like, I'm gonna stutter on that word. Eric Rieger Really? Ken Brown Yeah, no, yeah, it was bad. And so I would block and then I could not get the word out. And then it just became this facial contortion thing. So I'm extremely empathetic to the fact that communication is how you're labeled. So if you cannot articulate yourself, oh, he's so articulait he's must be intelligent. If you cannot verbalize what's going on, then so I'm really well, I went to speech pathology for years and then when I.. So I didn't learn Spanish as a child, I learned Spanish as an adult in med school and went back to the same speech pathologist that I went to when I was a child. And he was just like, crap, you're greedy. He's like you how bad you were. Now you want to like not stutter in another language, because it all kicked back in and then tremendous anxiety and everything. So the ability to actually communicate and a speech pathologist role to help somebody do that, whether it's somebody's post stroke, whether it's somebody that is autistic, whether it's somebody that stutters, is incredible because we're judged by how we actually articulate. And it's the social norm. And I love how you're saying that if I can get somebody to just acknowledge I can see that they're getting it.Eric Rieger Yeah Ken Brown That's what's cool. There's something in there. And I want to my my passion is the gut brain access, and I believe that autism is really no different than dementia. It's over activity, it's really no different than stuttering its activity in a certain neural complex, which prevents you from having the appropriate connection. It's all electrical. And there's some really cool stuff. Johns Hopkins is going to do a study on a molecule called sulforaphane coming up, too, because they're showing some deep some improvement with that, if we can find this. And so, the reason why I think it's so interesting that we talked about diet because I've seen in my own practice, autistic their 16 year olds, because that's the earliest I can see him. When we improve their gut health, their brain health improves. So to anybody that's listening that has an autistic child, I think that people like you are making a huge difference. And I think that we have to continue to realize that, that there are people out there working on a cellular level and there are people out there working on the functional level, and that's what you're doing. You're changing the moment. It's great if I say Oh, hang in there. for 10 years, there's a drug or a new study that will come out, but you're grinding it out. That's what I love. Paneez Kahkpour Thank you. Eric Rieger That's awesome. Ken Brown What's your favorite thing in that job?Paneez Kahkpour No session. No days the same. You're always keeping you on your toes all the time. Keeps it fun, and you get to play with kids. It's great.Eric Rieger Sounds creepy when a guy says it.Ken Brown So Eric, Eric actually tried to be a at home speech pathologist. But I mean, for some reason showing up in the windowless van. Eric Rieger Kind of.. just said candy on the outside. They asked, Why do you want to do this? I just want to hang out kids. That's awesome. Thank you, Paneez so much for coming. Paneez Kahkpour Thanks for having for having me.Eric Rieger Absolutely what an incredible show. Ken Brown You know ...I just love it. I mean, I just admire you so much. You. This is like, like we talked about the whole show. It's a story of endurance. perseverance of being open and vulnerable. Last episode, we talked about being open and what makes people that way. And every characteristic that we talked about you absolutely show the willingness to see new ideas. Try, just get out there. And if you don't succeed, just keep adapting slowly. Paneez Kahkpour The only way.. Ken Brown So where are you? I'm gonna put you on the spot again. Where are you at? 10 years from now?Paneez Kahkpour 10 years from now, hopefully still in remission..Hopefully, I mean..Ken Brown She said that she kind of looked at me like, well I don't know keep me in remission..Paneez Kahkpour That's on you. Hopefully in remission, you know, hopefully I went to grad school and accomplish that because, you know, working on that right now. Maybe working in a hospital, maybe have my own private practice something, something along those lines.Eric Rieger Now, I don't know you didn't prompt me because I don't know but I don't know if Paneez is one of the Crohn's patients that we have currently that is taking Atrantil and CBD combo is thatPaneez Kahkpour I was just on the CBDEric Rieger Just on the CBD. So I okay, yeah, that's what I wanted to give us your perspective and what you felt. Did you get more control over?Paneez Kahkpour Yeah, I mean, so the thing is I overall I felt great, but because not going on again. Thank you Remicade. I've been feeling pretty good.Eric Rieger Sure Paneez Kahkpour Majority of the time I don't really have too many you know, issues maybe a little tiny players here and there but nothing too big. So overall, yeah, I just feel good. I sleep well. You know, no complaints.Eric Rieger No, that's that's the awesome part. I get to see the patients when they come through just like you've been through and there's a handful that have just verbalized. I don't worry so much about taking, whether it happens to be Remicade or anything else like that as often They're able to space it out just simply because they feel like they've controlled their inflammatory process. They don't have the flare ups like that anymore. I mean obviously they're adhering to a specific diet for them. But it's it's curious because it CBD to me four years ago I didn't I didn't believe the hype at all. I had to wait till we proved it clinically before I thought there was anything to it.Ken Brown Well, we this is this is where I want to end up in 10 years I want to end up with the ability to heal people's guts and their intestines so that we decrease neuro inflammation and it all comes down to overactivity your Crohns is because your immune system is overactive. All we got to do is ratchet it back a little bit. And fortunately, Remicade figured out by doing it in one particular manner that worked really well which really well for you. I got a lot of patients it doesn't and I'm not bashing Remicade at all We love all and that's why we tried these different biologics. That's why Reed had an anticlimactic shock and he had to go and humera and his doctors you just sit there and you'll Wow, contrary to what people think we really all want to cure for this. Eric Rieger Sure. Ken Brown We really want to care we I could sit here and do if I had my 10 year goal is just Well, this show is huge and we've got you know, we're having fun doing it still in 10 yearsEric Rieger Yeah Ken Brown Cuz I like doing it and then I leave the show and I do like 20 Hemorrhoids and then I just go home Eric Rieger WowKen Brown I love hemorrhoids Paneez Kahkpour Sounds like a good line.Eric Rieger Big goalsKen Brown Big goals, has nothing to do with you know..Eric Rieger Someday I'll have a full tank of gasKen Brown I'm a.. maybe I'll have a new pair of jeans. I don't know. Yeah, no. Eric Rieger It's a little thing. Ken Brown It's dude, keep your I mean live the dream just keep the dream real accessible. Paneez Kahkpour Attainable goals.Ken Brown Attainable goals.Eric Rieger Weird way in that episode, but yeah.Ken Brown Well I want to..Well, we're almost done. I want to ask one another thing here. Just let's do a shout out to your mom because she suffered a lot through all this. Paneez Kahkpour She really did. I love you, Mom, thank you for everything. Ken Brown Wave at the camera.Paneez Kahkpour Thank you. Love you. The best mom ever.Ken Brown Can you say I love you mom and Farsi?Paneez Kahkpour ....Mom.Eric Rieger Big shout out to all the parents of all all kinds of diseases like that. I mean, you are your kids champion.Ken Brown This is the look at the camera one more time. This is this is the beautiful face of Crohn's disease.Paneez Kahkpour Think of Crohns and see my face?Ken Brown Yeah, and this is the beautiful face of a janitor at a..Eric Rieger Camp Sweeney.Ken Brown Camp SweeneyEric Rieger It's been a while but yeah. Well said it.Ken Brown I think that is a great episode. I think it's very touching. I want to thank Dr. Mike Wiesburg for telling his story. That is very compelling. Go over and Get the book in the end. You can see by the way he writes that and that was like five minutes. Yeah. Like I mean, you know his his novels are incredible. I want to thank you so much Paneez for coming on and sharing I know that it's like really personal and stuff but we just need to get the word out to the Crohn's and colitis foundation camp Oasis thank you so much for everything that you guys do for all of this. And ultimately, I'm hoping that through some polyphenols like Atrantil and CBD, we can start making people feel better heal their guts heal their brain, stop the immune system and we will eventually get to the point where we would talk remember that time when people used to develop Crohns?Eric Rieger Yeah, that would be a great day to get to in fact, you can help them get to that day by donating to the Crohn's and ulcerative colitis foundation and if you go to gutcheckproject.com check the show notes for this show. We will be certain to have the links to you can check out camp Oasis how to be a volunteer how to give to Crohn's and UC, it's it's, it should be a goal.Ken Brown If you go to KBMDhealth.com and put in a code Persian princess but has to be in Farsi, you get 120% off. Eric Rieger Yeah, good luck getting that keyboard Paneez Kahkpour I have it, i'll go use it right now.Ken Brown Eric we're losing money!Eric Rieger It's not gonna work.Ken Brown Don't do that. Okay, nevermind. I retract the Persian princess code in Farsi.Eric Rieger Thank y'all very much for tuning in again, check project Paneez. Thank you so much for making time for us today. Paneez Kahkpour Of course, Thanks for having me. Ken Brown Awesome. Eric Rieger See you all later.

Fecal Transplant Bacteria Science: Poo & Prep Matter

university gut health ibs gastroenterology san antonio texas ken brown learn more about dr kenneth brown atrantil

Play Episode Listen Later Feb 6, 2020 83:57

All right everybody It is now time for the gut check project. Let's talk about some of our sponsors for today's show, Episode Number 31. Of course, we're going to start it off with Atrantil you can get your own Atrantil at lovemytummy.com/KBMD chock full of nature's best defense against IBS and bloating polyphenols. Dr. Brown, what do you want to add to that? One of the things is that we know that the future of protecting our microbiome and if you listen to this podcast, you will realize that we're it's all about health span. It's all about protecting your health. And the microbiome is the most important thing that you can actually augment Atrantil augments the microbiome. If you happen to be somebody that has IBS and bloating well we fix that also. So in other words, if you have issues take Atrantil. If you want to protect your health span take Atrantil.So Atrantil, not only for your gut health protect your lifespan lovemytummy.com/KBMD, lovemytummy.com/KBMD. Don't get it from, Amazon. Get it directly from the Atrantil manufacturers themselves. You know what, because you need to just get on with this, I'm going to correct you on this. You said lifespan, I said healthspan. Two different things. I want you to be healthy. That's the bottom line. Doesn't matter how long we live. If you end up with Dementia, Alzheimer's Parkinson's, and things like that healthspan, my brother.That's why we get Dr. Brown on the show and not just me. So lovemytummy.com/KBMD. Now talking about KBMD, we also have another sponsorship, KBMD CBD. KBMD CBD is all organic CO2 extracted and has been used clinically where we gotten results correct?Correct Absolutely. So one of the things is everybodyis talking about CBD, CBD these days, but getting the proper CBD is the key here. If you cannot get direct access to a Certificate of Analysis, you're starting off on the wrong foot. All KBMD CBD lot number to lot number. Every single run, has an associated Certificate of Analysis so that you know that inside that bottle is exactly what appears on the label. And everything that we've ever or the Dr. Brown has ever found as a benefit from CBD has been tested in his own GI clinic and not just with himself with many of his own colleagues. So KBMD CBD, you can get your own at KBMDhealth.com. And you can also find the Dr. Brown signature protection package, which includes CBD and Atrantil. Now why would someone want to do that?That is great question Eric. And the reason why is because when we've been talking to scientists, we realize that when you take Atrantil with CBD, it actually augments your own endocannabinoid production. Meaning, you explain that please.Well, if you enhance your own endocannabinoid production, what you're going to do is give your body all of the elements that it needs to balance your immune system along with your nervous system. And by having that type of balance, you begin to decrease the, the negative effects of over inflammation. Or you could find out that you could sleep a little bit better that you just don't say have the same aches and pains. Essentially, there's a great reason that we're discovering that CBD is essential as a micro-nutrient that we could consume every single day. I'm so proud of you. Thank you. You've learned so much. I've learned so much.Go to KBMDhealth.com, use code GCP save 20% on anything that you wish to purchase.So ultimately, what happens is that the polyphenols Atrantil actually decrease the enzyme that breaks down your own endocannabinoids and that's how come I started getting into the science of this and I realized that every time everybody takes the KBMD CBD with Atrantil they do better. It augments, it meaning, they work together. 20%? That's on top of the discounts that already come in the...Sounds like i'm going to lose money on that. What's important, is that everybody can rest assured you will not have money as a barrier to entry for your health.You know, that's exactly it. I don't even care about that. So we're gonna lose a little money on this, but you guys get healthy. I'm on it, my kids are on it, my staff is on it, you're on it, your kids are on it, everybody's on it. Everytime you get in front of somebody. Our job with the gut check project is to promote health.100% And this is one way to do it. Speaking of promoting health, we have our first external sponsor that we'd like to go ahead and talk about that is going to be somebody who made it a an appearance on episode number 30. The Unrefined Bakery so unrefinedbakery.com, unrefinedbakery.com. You can use, code gutcheck to save 20% off your very first purchase. And it doesn't matter where you live, even though they are based in the DFW Texas Metroplex, anywhere you live, they can ship to you. Gluten-free, paleo, keto compliant, whatever you're after in your special diet. That's what they specialize in. Low sugar, breads, cupcakes, mix. It's incredible food, that just happens to be gluten free. What do you think of the of the foods that Unrefined Bakery made this week?Absolutely amazing. They were absolutely delicious. But, here's something else I want to say. I had a patient that just came to me, and they went to the Mayo Clinic they were Cleveland Clinic. They were like desperate, right? And they were told by their gastroenterologist that gluten sensitivity is not a thing. Weird. Guess what? Gluten sensitivity is a huge thing to me. Because every time I eat it, I'm pretty much stuck in the bathroom. So Unrefined Bakery. I love the fact that we brought them on. We had Taylor and Ann. And they, they crushed it. They're super smart.Definitely. They're dedicated to their customers without question. Dude, they have the same passion that we do, which is ultimately just promoting health, that's it.Absolutely. So I know, I had to laugh. This patient came to me and he goes, Yeah, my doctor told me that gluten sensitivity was not a thing. Like it, really is because I live it.Yeah, absolutely. Unrefined Bakery, unrefinedbakery.com, use code, gutcheck, save 20% off your first order. Make it a big order. So save 20% off a bunch of stuffed. 20%? They're losing money also.Absolutely. If you walked away thinking you can't have bread anymore, start here. They sell bread, they sell bread dough, they sell cupcakes, they sell cookies they sell like I said.Can you get on the rest of the show, because I'm gonna drive there. Right now. And go get some cupcakes.Unrefined Bakery. You're doing too good of a job of selling this, holy cow.We may not have a show, this may be it. This may be Episode 31 right here. So unrefinedbakery.com. Be sure and check them out. Use code gut check. And now we're onto the show. You're gonna love Episode 31. Dr. Brown is going to dive pretty deep and we'll get started here in 3,2,1. Alright everybody is now time for the gut check project. It's Episode 31, we got a special topic here today that Dr. Brown is going to cover. Has anybody ever thought about fecal microbial transplants almost screwed up the way I said it, just then.No, no, no, you can't screw up poop.You can't screw up poop. You can't screw up poop.No, so I didn't. It's like. It's like everything's fine.Yeah, I want to try something completely different here. So what, what happened and the reason why I'm to do this show, you and I is that I were surprisingly getting some reach. I got reached by somebody, instant messaged me from Sweden.Someone from Sweden, Sweden.Because they actually had GI issues developed bacterial overgrowth, SIBO. And then, in her desperation, she did a fecal transplant. In other words, she took somebody else's poop and put it in her body. So if this sounds weird, it's not that weird. It's something that's like gaining a ton of traction. And then she reached out to me because she ended up feeling way worse and developed several autoimmune issues. And that's what I want to get into the fact that FMT, Fecal Microbial Transplant is not a totally benign thing. And if, Are you open to maybe having me interview her?I think it'd be fantastic if you interviewed her. There's nothing like real world conversation with people who have real world elements with real world answers.That's so awesome. Because one little thing that I want to discuss is a recent article was sent to me in the Journal of Psychology Okay? Where openness to experience is linked to several things. So I would like everybody listening. The gut check project is about checking your ego at the door and being open to different things. So one of the things that I'm really proud of is that every time we do this show, people reach out to us we get a lot of email, we get a lot of people talking to us, and then I have to address it. Well, this particular show where I interview Helly, I want to make sure that if you have IBS, if you have SIBO, bacterial overgrowth, if you suffer from anything. Watch this because what I'm going to do is put a face to the disease. And she was so kind to reach out to me and say, film me, and I want everyone else in the world to know. So the Swedish person, who was very open about everything. She has exactly what I do in clinic, every single day. So what you're going to watch is what I do with her. It was a two hour interview. I cut it down to 15 minutes Right? So if you know anybody, please refer them. If you actually wants to sit there a little little bit more, we have our friend, Shivan Sarna.Shivan Sarna, with SIBO SOS Summit. SIBO SOS Summit, yeah, absolutely.SIBO SOS Summit. She's interviewed all the experts. I actually directed Helly over there, but more importantly, be open. So if you're like, if you're about ready to go ah, no, I'm not into it. What I'm going to tell you is, a recent study came out in Psychology Today, that talks about openness. All right. And the fact that you said open, makes me super excited.I hope I'm as excited when this is all over.I love how we show up. I hold papers and you're like, where are you going with this?Sometimes you give me papers I don't even know they're there. Alright, put simply.Okay.Openness is the drive to explore novel aspects of human experience. Okay? Now, here's what's fascinating. This article did this whole interview where they looked, and 95% of Americans feel that they are more open to new experiences than other Americans. Well, Wow, that's amazing.There's only that 5% that everyone's competing with.I know. So it's funny, because as we sit there and look at this, we realize that 95% of these Americans responded that they're more open than everybody else. But, as it turns out, when they actually went through the rest of the questionnaires, they're not. Okay. As we age, we become very entrenched in our own habits.Familiarity, I'm sure is probably already 100%. It's gotta be.I love the fact that I threw a curveball at you here on the show. And I'm like, you look I'm gonna we're gonna do a zoom with a person in Sweden. So that's pretty much our gas this time.Sweet. So, anybody who is open to experiences, they have shown that the people that are more open to new experiences tend to be financially better, tend to have better relationships, and they tend to be happier. Okay. So as much as you sit there and say, oh, well, I have my routines, being open and jumping off bridges and that, I don't mean that literally. Sure, sure. Yeah, yeah. The figurative. Figuratively because you and I jump off a lot of bridges, figuratively. But doing that more, actually results in a more prosperous life.Doesn't that make sense though, because whenever something's new, it expands your mind. You have a new experience, and doing the same thing over and over again. Look what happens with people who have quote unquote, "stale relationships." They say we did the same thing. And if that happens, then you people always use the term spice things up. Where does spice come from? Spice comes from, from change, right? So embrace the change and take, take what's coming at you.Embrace the change. So what we're going to talk about today is a couple simple techniques. So this study, and then we're going to get into the interview. Okay? And then I'm going to, I mean, I wish I had some way to geek out like some signs. It's like, Okay, I'm going to geek out now because the article I'm going to get into..Yeah, geek out, like now we're gonna geek out. So I mean, I find myself I had a patient in that was a PhD, and I was sitting there, tell her about some stuff, and we started talking and next thing I know, it's like 30 minutes and we're way beyond the actual issues that she came in to see but I'm like, I'm like eating her brain about what she knows and, and she's like, Oh my gosh, hey, if you do this, and this and this and this and this. Like the inner connection of what we can do when we start pulling our mind power together, is really amazing. Yes, it's kind of what this is about. This is being open to new and novel things..Maybe Paul can put a little sciences geek out.Alright So I'm going to tell you how to be open. Okay So rather than argue whether it's good or bad.. so the number one nudge the edge of your comfort zone, ..Okay So it has been shown in human studies that the more that you push things, as we grow older, we tend to confine ourselves more and more and more and more. YeahAs kids, they will push themselves. And you know, they'll just try anything. There's no established boundary. There's no established boundary. As adults, we tend to say this is my boundary, so I should not do that. I am not going to dance, because that's not who I am. I am not going to be silly. I that's I guess that's why I love comedians. They just get up there and just throw down.Sure yeah, I love my grandpa or my granddad, used to have funny little sayings. And one of the things he always said is "you otta throw it against the wall, see if it sticks." I love it.You know, you turn, turn the key and see if it starts anything like that you he's basically just using metaphors for trying things out.We have one shot at life and we tend to limit ourselves because of the fear of the unknown.I would agree with that.Quit doing that. Nudge your boundary, push your confidence to levels. And guess what? It's okay to fail.It is okay to fail.That's the thing. Number two, the number two way to actually become more accepting in that to openness is prototype over perfection.Prototype over perfection. Kind of interpretation of that would be it doesn't have to be perfect to be used. Doesn't have to be perfect to be tested. Right?That's funny how you interpreted it that way. Because the way that I read it was Eric Rhaegar. And Ken Brown, we are prototypes over perfection.Quick, get some microphones and a camera. And let's see what happens.Now, so Thomas Edison made 1000 unsuccessful attempts at making a light bulb. Yeah. And he actually was asked, how did it feel to fail 1000 times. Edison's response was, I didn't fail 1000 times the light bulb was an invention with 1000 steps. Absolutely.So whatever it is that you're doing, whatever it is that you're trying to do, you're not failing. No. It just becomes a step in the process. Be open to more things. Hundred percent.Yeah, I couldn't agree with that more.And when you realize that people like Edison failed 1000 times. Step up. Yeah, no more excuses. And then this is my favorite, right? The number three way to be more open. Follow your curiosities, not your passions. So you have two boys Gage and Mac.Correct? And you know we always sit there and tell people follow your passion, follow your passion. But the reality is, a passion is a very weird and personal thing. Yeah. And curiosities. Are, can be stimulated in many different ways.. I agree with that. Curiosities can be built from different angles. They can be built from experiences they can be built from whatever follow the curiosity the curiosity will lead to a passion. I'm gonna brag on my oldest here right quick, because he does play competitive basketball and they both do Gage and Mac both play competitive basketball and Mac hasn't had this opportunity. So this story is really just about Gage but he has or had some opportunities after he graduates high school this year to go and possibly explore playing basketball in a smaller school setting, etc. But as much as he enjoys playing basketball, he, he doesn't think that's what he wants to define him. He wants to keep his passion as his hobby, and be inspired by being a traditional college student being able to discover because he's afraid that for him, not for everyone, but being a collegiate athlete would basically wall him off from his ability for exploration. I mean, that's almost verbatim how he described it. He wants to be able to be a young man to still explore beyond the boundaries of a basketball and I think that's completely awesome would have been a lot cheaper, on everybody play basketball but that's that's not we all live once and that's not what was going to make him happy.Is that fascinating? Because I know that I mean, we've talked a lot about Gage, Gage explores his curiosity..Sure.He plays music he artist does artists, he does video editing, he does different things. My kids do the same thing where I just didn't cure. I want to encourage the whole curiosity aspect of it. And I didn't even realize that that is what makes you open. Sure. When you're curious, you're open when you're open, you accept other ideas. When you accept other ideas, you accept other people, you can see that there's a whole path here. You eventually by being open, you have empathy. Oh yeah. You end up saying, I get where you're coming from. I could see what this is. You don't wall yourself off.Yeah, absolutely. Now I'll brag on my younger one Mac Mac is often times with his large massive collection of friends, which spans about eight years in each direction. He, he often times refers to them from their station in life if they've had like a struggle or big win I've heard him say, they must be feeling this because this looks like that this would have felt good or bad and then kind of gives their you know, their environment perspective. So yes, I agree with that that the curiosity would would breed empathy like that. That's really cool. So this particular doctor when they wrote this article, they said while passion is fickle, and high voltage curiosity, on the other hand is deep and abiding. When you approach something with a curious mindset, you're seeking growth and newness, for the sake of novelty. So stay curious, my friends.Yeah. And it sounds like somebody else who said that. Yeah. Somebody else I'm sure we can reference it becauseNot supposed to.So I just, I think it's interesting that and in this particular show, we're going to do something unique or we're going to put in a video of me interviewing a patient, but being open to new ideas being curious.Sure. That is the kind of stuff,so as a physician, when I'm curious, I went down some rabbit holes on this particular topic event. I bet.And I loved it. I love it. I'm a I'm a better doctor. This shows makes me a better doctor, this show is going on Shivan's webcast makes me a better doctor, I have to prepare for it. I have to do different things. I mean, we all have to sit there and realize, okay, I am going to be curious about this topic. I'm going to learn it, I'm going to do it. And then all of a sudden it opens up a new door and you're like, we haven't thought about that. No.That's what this shows about. So if you ever heard about Fecal Microbial Transplant, meaning poop transplant, that's what this is about, and there's a lot of hype around it. If you haven't heard it. I listened to multiple podcasts on this. Dave Asprey had an expert on I mean, like all people that I like to listen to.Sure Ben Greenfield.Ben Greenfield did this. Everybody did this? I'm going to sort of rock the whole ship here. Okay, today, I know. Let's be open everything. Let's be open. The fact that if you're open, you're going to be open to ideas. You're going to be open to different perspectives. But the reality is it's gut check project, check your ego at the door. What we're going to talk about is SIBO bacterial overgrowth, IBS, and if you want to watch somebody spilled their guts and really be genuine and be open. I have an interview here that we're going to play in the next few minutes. With Helly from Sweden, nice and she was open and cool. And you're not alone. If you have any digestive issues, you're not alone, and that's the bottom line. So she the story is this. She got sick then she was not right. Then in her desperation, meaning like she had the typical SIBO stuff. She got a fecal microbial transplant, she went to a doctor, he did a colonoscopy and placed poop from another person into her. And then she got sicker. Oh, that wasn't what they were after. That's not what they were after, right? And then she went back to the doctor. He's like, well, let's try again. And let's try again, and then she contacted me because she developed a multitude of autoimmune issues. Interesting. And she is essentially, she feels like she's dying. Hmm. So I would not normally respond to a message but she said, Hey, I need your help. I'm like, Look, here's what we're going to do. I don't know if I can help you. But if you're willing to share your story, we'll play it and we'll learn together. So what I want is everyone, every doctor, every patient to listen to this and say we're going to find something new to fix people. That's what that's what this is about. So let's go ahead and turn it over. This is my interview with Helly from Sweden, who reached out about having complications from a poop transplant, Fecal Microbial Transplant.All right, tune in.So tell me a bit about yourself.Okay, I'm 36 um, I've always been healthy until 2015. But after Flagyl everything my health went downhill. I started it gave me horrible panic attacks, I started getting depressed in movement. This is this sounds strange, but I could actually feel it in my stomach. It was like a nervous kind of feeling. You know, when you have butterflies in your stomach, but it wasn't like a good feeling. You're like you don't have an appetite. It was just like that. Yes, brain fog and the worst thing I had ever felt in my life was something called the realization. You know, when I had nausea all the time all the time. For two years I had not imagined you have a stomach flu that goes on every single day, every waking hour for two days, for two years, that's what I had. And I lost my new job that I had gotten a week before I got Flagyl so I couldn't stay so I it for three years this brain fog and, and my my, because my also my bowel movements. I mean, I had never always gone to the bathroom every day. I got maybe once every two days or something. But after Flagyl my my stool wasn't the same horrible horrible fatigue. I the brain fog I couldn't focus I couldn't I was always panic this this panic was the worst. I wouldn't I mean, if you have panic attacks.So essentially 2015 you get the antibiotics. You start with this down this path you are you eat specially carby foods, you get very bloated. And then you ended up having quite a few beginning with neurologic issues where you had the brain fog, panic attacks and depression some sleep disturbance out of frustration. You had, insomnia, you you went to several different doctors One of them was an advocate for FMT, known as Fecal Microbial Transplantation. And you got ultimately over over a course three different fecal transplants. First one being with a colonoscopy. Second one being with an enema and then an enema again. Okay, so both, and after each one, you had a reaction to it where you had what you felt like the flu and you had lymph nodes that got big. And then since then, you've had very significant skin and scalp issues with Alopecia meaning your hair's falling out. You've had biopsies which are permanent. And now the really unusual one is the hypermobility and the feeling like your joints are getting slightly bigger. And, that is something that seems to be progressing with you right now. Is that correct?Yes. Okay. Yeah, it's in jaws, back. It just pops and pops everywhere. Okay.That is quite the history there Helly. And I'm very sorry, you're going through all of that. Let's try and make a little bit of sense. I don't know if I can help you. But I do at least want to try and explain a few things just so that you're, you're very intelligent. A ton of reading, I'm going to share my screen real quick. So one thing that we do realize when we talk about, this is a moving target as you can see, and so you have a history which is very consistent for somebody to develop bacterial overgrowth. We know that SIBO can happen if you go through a stressful event. If you take care antibiotics are having an infection. And you kind of had all three happen at a similar time. We know that that can affect the motility and all comes down to motility. So you've already learned the basics of bacterial overgrowth, a SIBO and you understand that it's a can be population of bacteria growing where it shouldn't. So when you eat the bacteria break it down. These are just some recent studies that we've been looking at that kind of show how these different gases can affect things. So this is the effects and mention of how methane affects ileo-motor function. And if you listen to Dr. Pimentel talk, what he discovered in his lab, is that what the methane does, it doesn't just shut it down. It actually makes your intestines do an uncoordinated contraction. So it's like it just sort of spasms. And when it does that it doesn't move anything, thus allowing bacteria to continue to grow. Now we know that you drew out both hydrogen and methane. And we do know that when you have hydrogen, if it can actually bind and produce hydrogen....But more hydrogen. Yes.More hydrogen. So what what I see in my practice is that it is the multi biome. It's how these different organisms interact with each other, including fungal organisms producing possibly CO2 or the or the methane back background. Now hydrogen sulfide is a big deal, because what we do know is it's it can actually, the cysteine residue that normally reproduce on our diet gets absorbed and gets converted, but when you have bacterial overgrowth, it produces hydrogen sulfide, which leads to inflammation. Ultimately, inflammation is the root cause of all of this. And so what I think we're seeing in you, yes, that you have root causes the inflammatory process. You're exactly right, that when you had your your Genova stool test, that when you had the fat in there, you are mal-absorbing fat now are you mal-absorbing fat due to bacterial overgrowth, it could also be pancreas and we do see this overlap with that. But it is completely linked all these different things that a lot of times other doctors say well, you just have chronic pain, Fibromyalgia fatigue, migraines, but your initial presentation was all about the brain. The thing that I think you'll find it interesting is that once we know that we set this inflammatory cascade off, I want to show you this arrow right here. Yes, new data has shown that when a mass cell gets stimulated, it'll release histamine and serotonin proteases. But the histamine itself will actually stimulate the enteric nervous system, which will go straight to the CNS. So when you mentioned earlier, I do know that there is a gut brain connection vaguely? Well, it's mediated through the entire nervous system and it is very, very, very sensitive. So have intestinal inflammation, there is your gut brain connection. So if you look at this, the new evidence is now showing that this gut brain connection is in all different kinds of Dementia, Autism, Anxiety, ADHD, you know, the newest term it's really fascinating is leaky brain, because what they've done is that they've actually shown that you can soak colonic tissue in inflammatory mediators. And then they soaked blood, the blood brain barrier, and they show that both of them become permeable. So know that there is no doubt about it. It's not in your head, that whole depersonalization, that anxiety that depression can all be related to leaky brain. I do I am getting into quite a bit of research and cannabidiol or CBD. And there is there are some in vitro studies where they actually looked at how they can improve the blood brain barrier, which ultimately helps with all that so my fear is that these kind of things will continue. Like like you're already worried, continue to progress to lead to more autoimmune issues to lead to more things like that. So the whole FMT thing is really fascinating to me, because we got very excited about it. And then the FDA came in, and then and then they basically pulled the plug. And then we said, no, it's very effective in clostridium difficle infections. Yes, I know that. Yeah. And so that's what it's really only allowed for here, though, the whole concept of just saying we'll just take somebody's super donor a poop. Getting back to the how we prepare it, you may have a super donor right here, meaning you have a diverse microbiome. But once we process it, you may decrease the viability of that even if you do DNA analysis, you don't know if that bacteria is viable. So what I'm getting at is I think it would be very interesting to, in somebody like you, let's say that we advanced the science of this we can go oh okay, Helly, I think that unfortunately, we this particular donor did not have enough of butyrate producers bacteria. How do we get more of that in that? I am a big fan of spore based biotics. megaspore biotic.Megaspore?Yeah, so if you want..That's a probiotic, how can I take that?So I want you to go to our show, I actually we actually interviewed their their CEO, PhD, ..., and beautiful how he explains the science of probiotics. And it's incredible how he explains how the spore based biotics send signaling to other bacteria. So one of the things that they can do and the reason why we're teaming up is because we realized that the polyphenols and Atrantil can actually help feed the spore base bacteria. And what it does is it goes through and doesn't become out of its spore phase until it gets to the illeum at which point signaling goes it goes, Oh, we're gonna end up in the colon. Then it gets to the colon wakes up and starts tapping other bacteria and goes hey guys, we need to diversify a little bit. And they've actually shown that they can deliver vaccines this way and stuff. So the whole concept of spore based biotics is, is really fascinating and new barnwood spore based but so..But can I just ask you Atrantil I have there sir, I know that three ingredients. One is from peppermint, which is fine. I just don't know all that much from about this bark tree thingy.. is it?Well, you know that all really good questions all extremely complex. So, the bark you're talking about is Quebracho, Quebracho Colorado. That's the thing that makes us so unique is because we actually are the only product that has this. Quebracho Colorado is a proanthocyanidin or a tannin. So it's the tannins are proanthocyanidins combined into a large molecule. So the thing that we needed to help with SIBO is that we needed Atrantil to be a poorly absorbed molecule. So when we were talking about scientists, then we looked at all the animal data that had been done. And so what we do know is that in animal models, sheep and cattle that are fed this tend to have a much healthier microbiome, they tend to produce better milk, they tend to have increased weight gain and things like that. So from an animal perspective, we've been feeding cattle for a long time. from a human perspective, you're getting it in a lot of different sources that you didn't really realize, for instance, wine. Things like that, you're getting a lot of this. polyphenols, yeah, but polyphenols is a huge umbrella. Before every time somebody does some research on it, it appears that they are beneficial in ways that can that can become very complex. So this is that whole post biotic conversation that when you take a polythenol and or an undigested polysaccharide that gets to the colon, bacteria can break them down into different things. There are different molecules so that bacteria can break something down, and then produce a molecule called eurolithin. Eurolithin signals old and sick mitochondria to die. So that is my topic. So this is this is the kind of complex signaling that's going on.So when they die, those new mitochondria that does the body produce more or?..Yes, so it's like autophagy. Autophagy...YesIt's mytophagy. It's just the signaling to say, hey, you're an old and functioning powerhouse. And we need a new one over here. So okay, so then the big argument if you talk to in vitro scientists or bench researchers that look what they know is that these polyphenols like reservatrol, like berberine, like, all these molecules are similar like quercetin like tumeric all these. They'll say, Oh, well, one of the problems that Is that it actually creates a little bit of stress on cells. And so that's that antioxidant thing that you're talking about, which is too many antioxidants, then we don't know what it does. in vivo, I think what's happening is is that that is a version of hormesis. Actually, I think there's a term for it. It's called xeno- hormesis, meaning you're outside of hormesis is the adaption to a stress. So the reason why you work out and the reason why exercise is functional is because that's, that's a hormetic response. The reason why Oh, you're in Sweden, you guys are loving saunas, right? You guys are a big sauna society?It's more Finland. But yea.I'm a huge sauna fan, because that's a great example of turning on, heat shock proteins. And so what that does is you stress your body a little bit to make it adapt more. So you get this bigger, this bigger response. I think that the whole emerging role in the US were we're really limited by the research that we do is usually funded by pharmaceutical companies. Yes. Here that's what that's really what I'm trying to do is try and bridge this gap and say, okay, how do we look at some of this consistent research that's been done in the lab done in animals, some small studies in humans and say, can we translate this to benefit somebody like you? So I want I what I will tell you all I will do is I'll try and dive more into the FMT thing ask around if they've had some different challenges like this. And in the meantime, I hope that this helps you discuss a little bit more with your doctor and.. I will.. You know Helly, I think we should probably wrap this up. But..Yes. So what's the next step? You will you will get in touch with me when you've found someone and then we can set up a meeting for, for them for the new thing for the new recording. The show or what..Yea, we need to heal you and bring you back on so that we can heal? .. Next step is for you to tell everybody to watch the gut check project so that maybe one FMT expert will see it and go, okay, I'm willing to talk and then we can pick their brain. Okay.Perfect. Thank you so much. So. So..Hang in there. I hope that this..I will. I hope the zoom at least helps you to relax a little bit. And we know that people are still trying. There's a lot of scientists out there working on a lot of these things. The joint thing, I'm a complete loss. I've always thought of the EDS as a genetic thing. But then again, we have this whole epi genetic field where yes, you carry a gene, and then something happens that turns it on that's another process. So.Yeah, yeah. So it will be interesting to see if I have that gene. I'm going to ask for investigation in that too, because if I don't have it, then it really really is proof that it it's something with SIBO or from the gut. Yeah, and I would know.Yeah.Fascinating. Yeah.. Yeah. Okay. Dr. Brown, thank you so much for your time. And..Helly thank you so much for allowing us to share this with our audience. A lot of people realize that you put a face to a problem. A lot of people feel alone when they're doing..Yeah, yeah. Yeah they do. Hopefully we can figure this out? Yeah. Okay. Dr. Brown, thank you so much I don't want to take much more of your time now. Thank you. You too.Keep in touch okay? I will. Thank you. Bye.Alright, so we're back after the video. Hey, I get to see you at the procedure setting whenever we do the colonoscopies. Is it like that every day in the clinic side because we don't have those kind of interactions with the patients whenever we have them come through so I mean we just heard about the Hashimoto Ehlers-Danlos and screwed up how to say.Ehlers-Danlos.Thank you, but so we hear that that's what she said. Alopecia. Losing hair. Yeah. I mean, this is a beautiful woman who's this has disrupted her life. That's why I wanted it, you know, and thank you to Helly for letting us do. Thank you Helly very much.Yeah, you're right, Pedram. Yes, it actually adds a face to the disease. This is what I do every day people come in and they're desperate. And I want to talk about something unique that nobody's putting this thing together. Let's do it. And hopefully, people like Shivan Sarna can spread the message about what I think I uncovered. When I was preparing for this, with with Helly and listening to her like, Oh my gosh, wait a minute, I think I know what's going on. Because the key to Helly is so it was a two hour interview and I cut it down to 15 minutes. So there's a lot that's left out. Okay. Much like Shojai Pedram, what's his name? Yeah. When when he interviewed me for his Netflix movie, and we did Like 30 minutes of filming, and I got like 30 seconds of airtime.Well, the goal is not through everything. Not all golden hills.Pedram Shojai. Yeah. Pedram Shojai. Yeah. So he's got he does this docu series.You said right the first time he did it with a with a last name comma first name. Oh. So yeah, that was a you end up on the editing floor and I remember like to love it said why don't you just be more interesting and you'll make it into the actual film..Love it holding back.Alright, so anyway, so it was a two hour interview that we that I clipped down so that the thing that people want to hear and if you're that person, and if you have SIBO or IBS or autoimmune issues, there's a high likelihood that some of what she talked about is relevant to you.Correct. Which the thing that kept resonating to me is the anxiety. So she can deal with most of it, but the anxiety and the depression and the panic, never had in her entire life and just something happened. So that's what I want to get into post fecal microbial transplant. She ended up having all these issues.Yeah and your right, having anxiety basically takes away the ability for the coping mechanism to deal with the other present problems. And it's just a it's compounding the issue.Yeah, it's like insult to injury. Yeah, yeah. So you can have gut issues, but now you're having brain issues.And I can't even reason through it without feeling kind of terrible. Well, I want to explain all that. And I started looking into this. And then I started doing some Google searches, on FMT, which is fecal microbial transplant. Sure. And one of my partners that I was gonna interview Dr. Ackerman, who's actually done a bunch of this. We started talking about the consequences of this, and hey, we don't really understand exactly what's going on. So if you Google it, it looks Looks like it's the panacea. People are offering this for autism, Parkinson's or Alzheimer's. They're saying I have the cure to this. But I'll let you know right now that the FDA is regulating this because there's been recently two deaths on fecal microbial transplant. And so the FDA is getting involved. So a lot of these different clinics and stuff are doing in outside of the US.Yeah, Mexico, Mexico, and Central America, Bahamas. Exactly.So patients always ask me about this. And if I had a way to say I'm about ready to geek out, I'm gonna geek out. So I want to go into a deeper discussion into the science and talk about improving the risk and improve the beneficial effects of fecal microbial transplant. I remember I've had so many friends call me up and they're like, hey, my mom has Dementia. Do you think a microbial transplant ? If you've never thought about it, it seems weird. But once you're desperate, it seems like the easiest thing that you can do. Sure. I'm gonna take my poop from this good, healthy person, but in somebody else, and people are discussing how it affects all these other diseases. This is an example of how somebody did it. And it unlocked diseases in her..Interesting..The epigenetic phenomena. epigenetics means that you have genes in you. And then when you have an environmental shift, you end up unlocking these genes and they become relevant. It's super complex. So in my own practice, I've actually had twins that had all sort of one had ulcerative colitis, and they gave a fecal microbial transplant from the healthy twin to the the one that had ulcerative colitis, and they did it multiple times. And so the colitis better.Good. Interesting.She also took on the traits of the twin. She ended up having acne, she ended up putting on some weight, she ended up doing some different things. Fascinating. Yeah, think about that. I can sit there and put this. So then I started looking into it. And then there's mouse studies where they have looked, and they have shown that if you take a mouse that has Parkinson's, and they can genetically modify mice to have that, and then you give a non-Parkinson's mouse or a non Parkinson's mouse and you transplant, they end up developing Parkinson's. And that happened with blood pressure, diabetes, stroke, obesity. traits get transferred in the bacteria, it's nuts. So we sit there and go, Oh my gosh, that's like a big deal. So The original studies that have actually been done have looked and humans have shown this, where when they do a microbial transplant, nobody's writing about this. Everybody's saying it's a fantastic thing. Sure. There's this biome.org thing where they're collecting poop and they're given to people. What I want to get into is why I'm not saying it's good or bad. What I'm what I want to discuss is the science of how bad things can happen...which is very unpopular. Like, everybody wants it to work. Everybody wants it. So do we.. we'd be awesome. But..So like in Helly's case, she developed, I really think that she developed Ehlers- Danlos syndrome from it. It's nuts.Yeah, that is nuts. And just just as a caveat, this is not to undermine the research the application of FMT whatsoever. It's just basically just what gut check projects for let's discuss everything that's applicable here.So in a recent review, so FMT, I'm just gonna refer to as FMT, fecal microbial transplant has emerged as it legitimate treatment for the FDA recognizes it for C. diff infection, Clostridium difficile infection, which.. which is real bad. What happens is if you take antibiotics, you can actually wipe out all your other bacteria in one lives, and then they just sort of colonize and create habit. So we do know that it works very well for that. But in a recent review, 2 to 6% of people that have actually done FMT had very serious adverse events. Infection was noted in 2.5%. One of the problems is that the current screening process is very similar to blood. So if I'm going to take your poop put it in me, I'm just going to say do you have had a, b, c, AIDS.. you're good? Because we're treating it like blood, but it's not blood. It's not blood. We don't know enough about it. Yeah, so the current process is that this is what we're actually doing. And then I started looking online, and I found out that there's all these DIY, I do it yourself. Hmm. websites that tell you how to do it. So they're not even screaming for that. They're just saying fine. Now that I do not know, there's DIY websites for how to do an FMT on your own.Dude, I got so deep into the weeds in this thing, the fecal microbial transplant thing everybody wants to say it'll fix I mean, it'll fix everything you name a disease, somebody saying that it fixes it. This is what I want to talk about right here. This is why we do this show. The problem is that right now, a super donor, which is what Helly had. So her doctor gave her a super donor, which is a somebody that has no infection that they could find, okay, and they had a broad microbial species is more important than anything else.. What we don't really take into account is how does that super donors bacteria that that person developed their entire life. And they interact in an epigenotic way, meaning that they actually interact with your body. Why would that be the same as you? I don't know. Because, you know, it being a.. because it essentially a micro environment that's inside, what if you don't live in the same region of the world that I do? What if you don't participate in the same activities that I do?If you don't eat the same foods that I eat? It's there's a lot left open to interpretation and understanding, it seems to me.Totally. And then as it turns out, one thing that we're not even discussing is the byproducts of bacteria.. So when I say byproducts, I don't mean that as waste. What I mean is that the bacteria, the bacteria that we have in our bodies, that our micro biome produces certain beneficial thing..Urolithin and all kinds of cool stuff like that..Post biotics.Post biotics. Well, I I love it because when I gave the lecture at natural grocers, I was talking about post biotics and one of the dietician said, Well, what about short chain fatty acids? And I thought on a local level butyrate, which helps colonocytes? And I said, Well, I, I don't consider that a post biotic. She's like, I think you should reconsider, because the reality is that those short chain and then guess what she was 100%. Right. She was spot on. Spot on. Yeah. So props to natural grocers to hiring super smart people and teaching me and as it turns out, the short chain fatty acids probably pay a huge role in this whole process. Sure. It's a byproduct of bacteria. And what happens is when you eat vegetables, or complex polysaccharides, or prebiotics, or polyphenols, they all kind of do the same thing. They basically go to the colon where your bacteria then break them down.. and they produce certain short chain fatty acids, these short chain fatty acids interact to the body in different ways. So it sounds really chemistry, but it's one is called butyrate, which as it turns out is fantastic for your body sure what it's called acetate. Oh, acetate, is that the thing that develops when you workout really hard and deplete your ATP? Yes, same thing. So, as it turns out, that crosses the blood brain barrier.... And creates inflammatory process... So these short chain fatty acids, what I'm getting at is I'm going to take somebody else's poop, put it in you, and we're hoping that it all works out. This particular article looked really deep into the different short chain fatty acids that are actually produced.. And in Helly's case, even though she got her transplant from a super donor. I think that one of her issues is that her body's own micro biome may have interacted and she produced more lactate producing bacteria interesting, which crossed into her brain which caused her panic attacks.So lactate of course, is something that we measure on somebody who has over activity if somebody has a rhabdomyolysis, and then there's all kinds of implications of too much lactate, and of course, that's related to lactic acid. You get that whenever you're fatigued, so she has bacteria, you can only imagine if they're over producing that, that that would, of course make her fatigued and more inflammed, right?Absolutely. Satish Rao, who's a gastroenterologist all over gusta George's, the SIBO expert. I think Shivan interviewed him actually Satish. Yeah, yeah. He published a study which showed that if you take a lactate producing bacteria, that those people that take a probiotic with SIBO, they end up with more anxiety and more depression. And it all fits.Interesting. So Helly if you if you want to Interview Heloise like the thing that bothered me the most was my anxiety and my panic. She even talked about a deep personalization experience, where every time she she's like, I don't get it. I've never been like that. I'm telling you that the bacteria produced lactate that cross the blood brain barrier that resulted in brain inflammation that resulted in your anxiety.The behavioral change.A behavioral change. Yeah, just from bacteria. That's, I mean, it's, it's wild, but it's, it's probably true. I mean, micro biome has evolved in the gut together, and it's very complex. They signal if you watch our show with Kieran, he talks about how the bacteria talk to each other. Definitely. So when we sit there and say, oh, we're going to wipe this one out, or I'm going to give more of this one that may adversely affect the chain downstream.Well, it's probably all the more reason why a DIY FMT is a is a poor idea. Your there's some much more research needs to be done.You know, the whole FMT thing is, is scary because well, it's just because we just don't know what to do know. We don't know enough yet. We don't know enough. Yeah, Peter Aditya said it past where he was like he goes, we have the ability to test tool. We don't know what to do with it. Yeah, he did. He's the first person just blunted it down.But he said it several times. And I agree with him. Yeah.So the one thing we know is that we do need a high diversity. Correct? So the more diverse your microbiome is, the better. So now here's sort of the cool part. In a healthy individual, the colon is predominantly, gonna get geeky, ready?Ready. The colon is predominantly dominated by obligate anaerobes. Obligate anaerobes, okay. Do you know what that is? Lack of oxygen. Lack of oxygen.Yeah. They need to exist in order to proliferate with a lack of oxygen. Correct? Correct. Okay.So they need to, they will proliferate in an article oxygen free environment.. names like bacteroides infirmities and these different phylum that we talked about. This allows for a higher production of butyrate, the short chain fatty acid.Which is beneficial to colonocytes.Which is beneficial to colonocytes. And as it turns out, it's beneficial to all intestinal tract stuff. Colonocytes just is a fancy way of saying colon cells. So just so you know.You're so nerdy. Yes, you're right. A lot of sites are colon cells. Alright, so our friend Dr. Pimentel, he's actually described how when he's been treating people with SIBO, bacterial overgrowth, small intestinal bacterial overgrowth that he has shown that there are blooms..Oh okay.Of facultative anaerobes and he uses the terms blooms.Facultative anaerobe. What he means is somehow the SIBO people end up with more facultative anaerobes in the colon. So, SIBO is small intestinal bacterial overgrowth, bacteria growing where it shouldn't. And then when we try and look at them, he's got the technology at Cedar Sinai, just show that they're colonic bacteria. They have an overabundance of facultative anaerobes. Meaning.. what? What does that mean?I don't know. Because when you use obligate anaerobes, it's almost like an interchangeable before I didn't really I'm not really used to the adverb, oblogate and facultative so kind of explore that. This is new to me.Yeah, it's awesome. So basically, it's a badass bacteria that can swing both ways. Oh, if you give it oxygen, it will.Different result?It will say I can deal with oxygen. I prefer anaerobe. Wow. So if you take the oxygen out, I will do better but in Oxygen environment, I'm going to proliferate more, but meaning you have this balloon. So Pimentel describes it as a bloom, meaning we're producing too many facultative anaerobe..Interesting Oh it's super wild.So just as an analogy, what we're saying here is there are some freshwater fish and there are saltwater fish, but you also have those fish that can basically change the way that they handle their respiration and their, their salt water content. And they can exist in both brackish they can exist in brackish water and go back and forth between fresh and salt. So this is kind of like what a facultative..You know what, thank you for making that analogy, because I wasn't thinking like that at all. But yeah, you're exactly right. The transitional bacteria. Yeah, it's a transitional bacteria that will adapt to the environment.Interesting.This is really interesting. So what he has said is that when you have these blooms of facultative anaerobes these bacteria will prefer an anaerobic environment, but they will switch to oxygen and grow quickly. This may be the root cause of dysbiosis. So this could be the reason why I see the SIBO people. Yeah. And they're bloating, it's better but they're still constipated, they're still..So the problem is just adapting.So what was it turns out is and we're going to get into it a little bit. We may be promoting the facultative anaerobes. Okay.And this is why it's a chronic condition. So if you're somebody that is suffering with SIBO I think that maybe your diet choices could be singularly selecting a facultative anaerobe, which does not produce butyrate.So when you're doing current, we need to take things that encourage butyrate production that we're getting to?That's exactly what I'm doing to. So I'm circling around everything where I'm like, we are not producing enough butyrate or body.So knowing and I don't want to jump ahead, but just to bring the audience along, knowing kind of that we want that and that that is typically a byproduct of the bacteria that we already have. I would assume the most natural way for us to execute this is to give those bacteria the tools to make butyrate correct? Is that where we're going? You're spot on. You're a smart Dude, you don't know about that?But I think that I want my, my colon bacteria to produce butyrate.So this is all a lead up to this one particular article, this to my knowledge. This is the first article to address how the actual process of FMT may affect what we're doing to people.... And when I think back to Helly, I'm like, I think this happened to you. Yeah. So currently, if you take someone's poop. What they do is for a fecal microbial transplant, you take someone's poop, you screen it for the typical pathogens. So you're going to look for AIDS, Hep C, whatever, the same stuff we always do for, for blood and they're gonna say, look, it's it's not there. And then they will label them as a super donor if they have a huge diversity.. so now your proof is actually worth something if you actually want to, I know that you donate a lot of plasma and sperm and everything else that you do to raise money. It's, it's all I could do to get here today. Yeah, I know, it's for gas money. But now, if you actually have, if you're a super poop donor, you can you can label that one on there. It just sounds like another 30 minutes of my day.So a super donor, somebody that has actually a broad diversity of, of bacteria. And so in Helly's case, what she did is that she received a colonoscopy when they were they did there and then she did two enemas afterwards. Okay, so they did a slurry. So I started getting into it. And I started looking at this. And this particular article made total sense to me. I'm like, why would Helly have such horrible issues when they've used this stool? So this particular Institute in Sweden uses this super donor all the time, they found what they thought was a super donor. These guys showed the problem is, is that the process is to take someone's poop. And you mix it with sterile water.. and then you blend it.Okay?You blend it...Meaning that the blending process draws oxygen into the compound. So now you're facilitating not the action that you wanted. And there's going to be oxygen dissolved in water. It's the first time ever that somebody has thought about this where they said by the blending process by the actual process of what we're doing for the fecal microbial transplant, we're automatically promoting facultative anaerobes, not obligate anaerobes. Wow, interesting. And it's in I would imagine by proxy, now you're decreasing the byutrate production of these exact..100%. Okay. And that's exactly what we don't want, right?Yeah. So they actually propose that if you're going to do this, so these, by having the facultative anaerobes means that we're going to have less butyrate. And we're going to have more of the lactate. .. the proprynate and these different short chain fatty acids, which by the way, they have shown that they took mice and as I mentioned earlier, where they when they transplanted, but one of the really cool things is that they show that the level of lactate not only affected the brain, but it affected insulin resistance and blood pressure.Has to if you think about the way the body responds to high exercise and fatigue, yeah, because that's what we do.So we're sitting here giving drugs to people were like, wait a minute... is the real way to health to feed the microbiome so that it produces more butyrate? So what they did is they took a mouse model, they went Holy cow, is there a way to produce more butyrate producing bacteria. So they did a fecal microbial transplant test where they did anaerobic slurries. OkayI don't know how they do that. But they basically kept oxygen out of the blender somehow.Okay. And then they stored it with prebiotics.Interesting, oh, and allowed them to.. And allowed the bacteria..To build some butyrate.To build some butyrate. Nice And then they transplanted the butyrate concentration in the mice that they did that with went through the roof. That's, that's what we want. That's exactly what we want. So then they looked at that and went, well, what What actually produces the most butyrate and I looked at prebiotics. Prebiotic is and an undigested fiber. And then I started looking at different studies. And as it turns out, people have done this research already..Polyphenols man.Polyphenols, so as it turns out, polyphenols, same ones, and Atrantil actually get the bacteria to produce more butyrate.Shout out to Joe, Joe Botel out in Exeter University in the UK who was doing the research on athletes and talking about butyrate just the same. That's that's exactly why she said that anthocyanidin polythenols were so, so powerful and helping athletes. So anyway, just to piggyback on that..Our little superweapon just sent me an article this morning that show that proanthocyanidins are extremely protective against Alzheimer's disease through the mitigation of rat reactive oxygen species. But I would counter that and say I I think this is all a big venn diagram. I think it's butyrate ROS or RNS, which is reactive nitrogen species and everything.That's so funny because that's what Joe was talking about was the ROS. side. And now we got your example with Helly, where we're trying to reduce lactate all the while producing butyrate. Correct? Correct. So you're exactly you're right. It's a Venn diagram on why the correct prebiotics to allow the right microbiome to break them down into the beneficial products that your body needs is important. And that's why having enough polyphenols would be essential.All right. So let's tie this back in what's the point of reading all these articles if you can't sit there and apply it? So one of the things I said at the early the first part of the show is that I love doing this because it forces me to be open.. I just told you why being open is important, right? It forces you to be open to accept new ideas and new Now let's apply this particular article that talked about FMT and how blending it creates oxygen, which leads to the wrong type of bacteria growing Correct. We do this in our SIBO people, we tell them to eat low fodmap. We tell them to do SCD we tell them to elemental. So we're trying to protect our small bowel. So we should increase fodmap. Well, in the reality, we're starving, the obligate anaerobes that wants to produce butyrate.Yeah, we're changing their environment.. We're changing their environment!They're response is to not make buytrate.This is the aha moment that I had. I went, Oh my gosh, I'm sitting here looking at this we bridged the gap. That's our job is to bridge the gap. Now I've got you know, the low fodmap diet. Yes, it'll make you feel better. But guess what, maybe that's why Pimentel goes now we have blooms. This is tying it all together. This is why now it's a chronic issue. So I'm sitting with my patients going Know what? So when we had Doug Wallen on the show, yeah, Episode 29. him and I talked afterwards and he said when he first started doing a plant based diet to get super bloated, when he powered through it, he's never felt better. I believe we're doing something wrong by telling people to restrict their diet. I think we should muscle through it. I think that we should tolerate the bloating. I think that we should take Atrantils, ifaxim, and neomycin whatever you're going to do carry out that exact thing in the small bowel. But you have to feed your bacteria so that you have the proper bacteria to produce butyrate and decrease the inflammatory response.That is really interesting. You know, I like analogies. So if you had if you had a dog in the backyard, okay. This is how just kind of picture.I know you love analogies, but sometimes your analogies I'm just like, what?Yeah, you got a dog in the backyard right? And you're supposed to be feeding him. I'm looking at you right now. I kind of feel like Rick and Morty.Yeah, as long as your Morty. Here we go hop on the spaceship. Let's go. Yeah. So, but I just think of it like a dog that's in the backyard and you're feeding it and you're feeding it and feeding and suddenly one day you don't feed it anymore and you have this nice wooden fence all the way around. That dog doesn't want to die. That dog is going to chew a hole in that fence and destroy your nice little fence and it's going to go and find food somewhere else now that that holes the breach that hole is the illness that hole is the overproduction of lactate that's kind of the..You're exactly right. It's it the dog is the bacteria wants to eat..It's going to survive, one way or the other.It's going to make its adjustment because it doesn't want to die. And so feeding it the correct meals. The prebiotics is probably a much better avenue than just avoiding everything that it was after.So expanding on your analogy, the way that I would view it is a little bit like this that you have I'm horrible analogies, I would say. Okay, so you have the same fence. You have the same yard.Yeah, you're really original.And you have two seals. And one dog. Okay. No water. Yeah. So there's so there's, there's a pool. So that PETA doesn't come. So there's pools so the seals are hanging out, and every day you out there, and you throw fish at the seals and the dog, and the dog doesn't like fish.Right? So the dog will chew its way out. Correct. The seals are like, Let's have a party, they get on their cell phones and they call more seals.. And then you end up in a backyard full of seals. And now you have to keep feeding fish. So the analogy is similar, but basically you're, you're pre selecting. YeahBy doing low fodmap all these other things. You're not you're not having a diverse microbiome, the ideal backyard would be a harmonious zoo. Right? I'm in a menagerie. Yeah.Much like your own backyard. That's right. So many animals. Would you please explain what a menagerie is? And why..You could go back to some other episodes and like going back that far, like menagerie is a word for a collection of a bunch of different animals. That's all you need to know.Yes. So it's, it just got me thinking, I'm like, I'm gonna change how I do. I'm gonna change how I treat SIBO, what we need to do is we need to get rid of the bacteria. And then we need to feed the bacteria. How can we do that? Oh, Mind blown. That's why I think Atrantil has worked over time. So as it turns out, I found a bunch of articles, mouse articles, human articles, movies, other things where I would have people that would come to me and be like, you know, I've taken it for like three months and now I'm better I believe that we fixed SIBO and then we fed the bacteria every single day.That's I mean, in all honesty, pulling the curtain back, that's not the way that we've been studying the polyphenol effect from the beginning. This is very eye opening, it actually is still, I mean, I can still see how FMT is could probably still be incredibly beneficial, but it has to be delivered and prepared the right way.Oh, these authors went into a whole different deal where they were trying to figure out how can we improve FMT? And they thought about, like, putting it with antibiotics to decrease certain bacteria, and then what they realized is, you can't play God..That's a mess. That's a hot mess. That's like chemical warfare. An that's how come they said, why don't we just throw a bunch of prebiotics in there and see what happens.Let me ask you, so what

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Ep. #477 Gut Health with Dr. Kenneth Brown

The Daily Grind Podcast

Play Episode Listen Later Feb 4, 2020 36:02

About Dr. Brown Dr. Ken Brown received his medical degree from the University of Nebraska Medical School, and completed his fellowship in Gastroenterology in San Antonio Texas. He is a board certified gastroenterologist and has been in practice for the past 15 years with a clinical focus on inflammatory bowel disease and irritable bowel syndrome. For the last 10 years he has been conducting clinical research for various pharmacologic companies. During this time, he saw the unmet need for something natural that could help his IBS patients find real relief. After working on the development of Atrantil for over 6 years Atrantil launched in the summer of 2015. Dr. Brown and his research team developed Atrantil with the intent of helping those suffering from the symptoms of IBS which we now know are caused by bacterial overgrowth. Learn More About Dr. Brown For info on Atrantil lovemytummy.com For info on Dr. Brown KBMD.com Today's episode was brought to you by BookNotes Get Smarter Faster By Visiting > https://booknotes.page.link/dailygrind For a FREE 7-Day Trial

Unrefined Bakery: Healthy Brilliance for Everyone

Play Episode Listen Later Jan 30, 2020 75:42

https://unrefinedbakery.comfacebook.com/unrefinedbakeryinstagram.com/unrefinedbakeryWelcome to gut check project. It's episode number 30. I'm here with your host, Dr. Kenneth Brown. Eric Rieger here sitting now with the founders of unrefined bakery in the DFW area. It's Anne Hoyt and Taylor Nicholson Thank y'all so much for joining us today. You're welcome.Founders? We got the stars of unrefined bakery here!The stars of unrefined bakery. The stars!We're glad to be here, y'all.I feel like every single show we just keep taking it up a notch. I'm like, how are we gonna beat this and you go I know how we're gonna beat it. We're gonna bring Anne and Taylor on.People that bring cupcakes.Yes, yes. cupcakes that won't make you sick. There you go. Yeah. And that is no joke. We're going to get to that obviously later in the show unrefined bakery being an incredible place that honestly it's great food that happens to not make you sick. I don't care that they feature that it's gluten free. And that it can be soy free or corn free. They have all of the things to take care of people who have food allergies, the fact is, the food is great. It just happens to be made of awesome stuff.Well, I'll be totally honest Eric, Eric loves your store he's been eating your get your food I have not heard of it. So this morning I'm in clinic and I had a bunch of people and I said well I'm unfortunately have to keep moving here I have to get to go to a show and I explained who I'm doing the show with it. Oh, I love unrefined bakery I go every time I go to a vegan conference through there every time I do this every single patient talked about you guys and I'm like Okay, we got some rock stars showing up today. I better have my game face on.Yeah,Well so quick. We just have to do it to pay the bills right quick. Don't forget that. Every gut check project it's sponsored by Atrantil lovemytummy.com/kbmd to get your discount of course it's polyphenols created by the gentleman right across the table from here Dr. Ken Brown. Anything to add for Atrantil before we talk to the ladies of unrefined bakery,Only thing to add is that everything that you guys tell your clients we also tell our clients which is we're trying to develop a healthy gut which leads to a healthy lifestyle which leads to anti aging which leads to health span. It's no longer about lifespan. It's about health span. How do we live a happy, healthy life where we share in this with everyone? And the relationship that you two have is so similar to what Eric and I have. I'm actually Eric father, and we started a business together.You look great! It's the polyphenols. It's an anti aging molecule.It's working!Well, you want to know what's really cool. Eric's a grandfather also. Yeah. You're a great grandfather. Great grandfather. That's amazing.It's news to everyone.So great. Breaking news! Here we go with it.I think that the I think that teaming up with unrefined bakery and discussing the issues of gluten and celiac disease is so close to my heart. So what I thought we could do today is I want to talk about celiac disease. We always geek out a little bit and clearly you to know your stuff on some science. Your sister's a physician. Yeah, so so you guys talk science at home. We'll talk a little science. We'll talk a little about celiac in general, get people up to speed get everybody's like, celiac. Do I have a wheat allergy? Do I have celiac disease? Do I have gluten sensitivity? Oh, it's all BS. Who cares? That's all just Hollywood stuff. We're gonna get into all that?And something to add a part that Ken doesn't always get to see is whenever we refer a patient to visit with our dietitians here locally like Susan linky unrefined bakery is always a stop that she's continuously recommended for the last several years because when people tried to bridge over to enjoying foods that they can then safely enjoy. Unrefined bakery has been a great, you know, beacon that you don't have to give up things that tastes great. You really don't. So let's start with the science. I mean, y'all y'all been a great savior for a lot of people.. Yes, I'm gathering that. You've passed that down.We're gonna let we're gonna let you guys go into the whole story about this talk about food but because this is the gut check Project, our whole motto is you check your ego at the door, and we can talk about anything. So today we're gonna talk a little bit about celiac disease I just mentioned in clinic everybody knew you guys. One of the things overview, it's a common autoimmune issue. If you're listening to this show, and you're like, ahhh celiac, blah, blah, blah, I'm not going to do this. Basically, what happens is your body starts attacking your small bowl, but pay very close attention to this show. Because as it turns out, the prevalence is increasing. A lot. We used to think it was like one in 3000. The most recent studies have shown that it's like one in 184. That was an Italian study that just came out not too long ago. We now know that 15% percent of new celiac diagnoses aren't people older than age 65. So you were quoting Alessio Fasano right before we started this, I had a patient today that said, you know, what, is it possible that you can develop this later in life and I'm like 15% of the new diagnoses are happening at age over 65. So if you think that you don't know or you will never get this. Pay attention to this because there is a chance that you could have this. So you may have celiac not even know it. We're going to get into that. This is not an allergy by definition. It's and it's a little bit different than gluten sensitivity. We're going to talk about all that and clarify it. But before we do this Eric is a huge history buff.Learned it from dad.So Oh, one other quick thing we always forget to do this. Although I'm a medical doctor, you're crna and you provide medical care. The show is not intended to treat diagnose or do anything that they should but we're just not just this is for fun. Yeah, but you're gonna learn a lot.If you have a funny looking toe get it checked out.Yeah, if you've got some unusual growth, go to unrefined bakery first. Do go to unrefined bakery first. We're gonna make you feel better. Buy a cupcake and feel better.You know what, that's it. Recommendation if you do happen, this is not diagnosing or treating, but it will make you feel better if you notice an unusual growth swing by unrefined bakery before you go to the doctor to get that diagnosis of it as you're munching. Oh, Take one to your doctor and bring some for their office. they'll treat you better..All right. So what I would like to do is our first ever history quiz. I'm going to sign awards and points on this one. So we're going to do a little history quiz. So the this is going to be about the history of celiac disease. All right. In 1888, celiac was first described by this person, Eric, you get first crack at the answer. 1888 celiac was described by this person. I don't know his name. I just assumed that it's Oh, you're pointing at something.Oh, it looks like was it Samuel? Oh, you want me to say Bernie Sanders.But so my son is horrible at improv. Just absolutely horrible.I thought you wanted me to guess. So I was thinking...You probably would have guesseed Bernie Sanders...1888.Well, he was there,Right Trump is happy with that answer.Tylor what would be your answer in 1888.I'm probably going to go with Samuel Gee the English pediatrician. Sorry.Yeah, little closer there. Okay got it. The English pediatrician. And what's your thoughts on that?I mean, Articus Decapidocious in 200 ad. Wow. Just saying I actually knew that. She did know that.And why do you Why do you know that?I wrote a paper for the Baylor journal in 2014.Nice. We've got some Smart people on the show today Eric.Definitely say it was a Greek physician, correct.He was Yeah, he cut open the stomach and was looking at how wheat interacted with it and didn't totally understand it, but knew that it definitely caused trouble called it coeliac or something. Second century AD. They were already realizing and we have people today going that's BS.Right? Right. Yeah. It's crazy. But I mean, you know, humans have only really eaten gluten for 12,000 years, probably. And so, I mean, bernie Sanders was there too. Yeah. Poor, Bernie, He probably invented the paleo diet.Eric, I have a question for you. Okay. Something occurred in the second world war that allowed us to realize that celiac disease was caused by gluten. Eric, why do you think that is?Well, Ken, is this when Wonder Bread donated millions of loaves and the Allied forces shot the Germans with ultra refined white bread causing diabetes,It would have worked and would have delayed the end of the war. Good guess i'm not saying you're wrong. That was really organic.You know, I know. You know. And so all right, Anne I'm gonna I'm gonna throw to you. It was the shortages, the food shortages and the incidences of gut disease went down. In the absence of eating the food they previously eaten right that cause trouble. So without eating the food they were accustomed to eating their gut troubles went away and absence of food soyeah food allergies discovered for sure. We're not just Baker'sNo. Oh my gosh, we have. So one last question before we do it, but if you have any history questions or history buff, make sure you pop into unrefined bakery, and throw out random questions,make sure you're asked for Anne on that one.Alright, so it was actually a Dutch doctor that noticed that his patients were getting better during that. So the last question, this is not going to be completely academic session. The last history question, Eric, how did this Dutch doctor figure out that gluten was the cause. I believe he locked his kids in cages and gavaged them with pretzels. And that's just wanted to see how sick they got. Okay, so we've had several shows where we described how animals have been gavaged and so Eric really likes the word gavaged.Especially when it's written out for me. I love it a lot.No, you're wrong. So I'll throw it. I'll throw this one to Taylor.So pretty close to that. Thank you. He did. He did take these kids. And he gave the celiac children and he gave them wheat. And then he just weighed the kids poop. And he looked for fat in it. See if they were passing that fat.Yeah. Did you know that? I did not know this. You didn't know that part? I didn't came up. Didn't came up.Yeah. And then so... that's awesome. That was said. He figured out that the toxic part of the food was it was alcohol soluble, and then they figured this out. So it's very fascinating that it's been growing for a long time. And now we're finally at this point. So celiac disease now with it, we know the history. I just want to give a quick recap as a physician about celiac disease so we can get off the science and talk about the goodness that is sitting on our table right here. Absolutely. So just to introduce, reintroduce again, it's Anne and Taylor, her daughter I was exposed to walking into unrefined bakery a couple years ago in Frisco. And it was awesome. My wife is gluten free. And I just happened to stop in I grabbed a few treats. I was like, man, I hope hope this is good because you don't always get a great tasting product whenever it's gluten free. That's so true. That's the common occurence.When I took it home it was instant delectable delight for for her. She's like this tastes fantastic. Are you sure it's safe? Right? They said it was. She felt great. Came back. We've we've been customers ever since. Great. Do you shop in our Frisco location? Mostly?Mostly because it's the closest one to our GI center. Awesome. So it's, it's just up the road on Preston for us to get to it. So yeah, it's great. So Ken you want to ask them how they got it all started?Yeah, absolutely. So celiac disease. We already kind of mentioned that. It's super prevalent. It's an autoimmune process that's happening. How do you guys know so much about celiac disease?Well, we're kind of science nerds to the core and Taylor's little sister Aaron got sick. In college. She broke her ankle and got got mersa in her bone marrow. And the treatment for mersa was very harsh. And once she got over that, which was awesome, she got just sicker and sicker and sicker, had strep six times one year and mono twice that year and was really failing to thrive and then began bleeding internally. took her to a doctor. He was amazingly efficient and asked her her heritage, and we're Swedish. And he's like, let me check for celiac disease. Sure enough, he biopsied her, and she had it and then we read about it. And I was like, Wow, you've been symptom taylor's been symptomatic since birth And I've been symptomatic since about 18 or 19 years of age with it really increasing after pregnancy. So we just were like, well, it's just food. Let's just stop eating it. So we did.And I was diagnosed with milk protein intolerance as an infant where I was taken off breast milk and put on solids by what eight months, eight and half months, roughly something like that. I mean, I had quite a few gut troubles. I'm surprised she had more children. Honestly, I had extreme colic. Right. So she'd been off a dairy for ever. And then Aaron, like said been symptomatic forever and we all went off gluten together and never truly never looked back to see what was just a remarkable change in all of our bodies. Did you have trouble getting pregnant?I had eight miscarriages.Interesting. Isn't that so interesting? Yeah. 800-900% increase in miscarriage. I don't even have to kick any science. They're gonna do all the science for me. That is actually one of the things that I asked my patients. Have you had miscarriages Have you have trouble getting pregnant? AndI did not. But I've been gluten free long before I had my children. I've been gluten free for I mean, and obviously that never came up like never came up.So when you said that your daughter was bleeding internally, you mean that she was anemic and they were doing the workup for anemia or she was actually actively bleeding.So, yeah, so we just took her right into it to a gastroenterologist that did a biopsy. That's the first thing you did. So she got...wasn't in her infectious disease doctor first who passed her on, given her heritage. I thought he looked at her and was newly out of school and was like, you know, your doctor from her doctor was newly out of school and askedher heritage, you're so blonde and blue, oh, you're hypoxic. We need to get some air in you.You know, Northern European.But it's different now. With with getting wheat across the world now it's equally distributed across the globe. But this is mean, right? 15 years ago. They knew a little about it. Super interesting, so we didn't even hesitate. We just went off gluten.Let me let me ask you a question as a mom because I have a 15 year old a 13 year old Eric has an 18 year old and 17 almost 16. Almost almost 16 year old. When you see a child that's sick that it just it takes everything out.You just see it like I see or I see kids that I'm like, Oh, you have celiac disease. Like I can just see it. I know what Aaron looked like as a baby. And her eyes were always Like terrible circles since she and Taylor always had like skin you know skin stuff and Aaron was just her hair didn't grow right like it just she was just pale and not well, and once she went off gluten it just it just changed. It was just it was just remarkable for all of us but more so she was truly she was just wasn't okay. She had I mean we I was symptomatic since birth but I had different different symptoms that my sister had and you had pretty much self selected already. Like you just didn't eat bread anymore. I wouldn't. I was kind of self selected as a kid. I was like, I don't like that. So you knew that it was making you feel bad. From a very young age young before I probably could even correlate it together. I know that I stopped eating those things and she'd be like, why don't you one pizza as I kid. Because we lived on it before you loved pizza.Erin and I ate more. Like a lot of people you eat. You eat more of what is making you sick because you don't understand it. You know your body kind of craves that thing.That's not uncommon so Aaron and I extra bread and pasta. We seem to we seem to see both sides of it. And with our customer base like we'll talk to moms whose kids have, you know, are celiac but also maybe have other combined allergies and she'll say it's really weird. He stopped eating these things even before we knew he was allergic. And I was like, well, we kind of have used the term self selecting for that because we see it's really frequently like kids, like my older son doesn't tolerate dairy. Well, he doesn't eat dairy. He doesn't choose it. He doesn't eat it doesn't have an allergy. No, but he just doesn't tolerate it well, so it's interesting how they you already sort of know that it's not a doesn't jive well with your system. So you avoid it. I did the same thing without even knowing it.Well, that's kind of how my wife started. She She was like, I, I feel bad and I don't know why I feel bad. And then suddenly, she starts drawing associations to whether having to be enjoying a beer or bread or pizza. Then suddenly, like what what do all these things have in common? I need to go get checked out. But back in the day because I can remember seeing a Dr. Phil Donahue show. And they had somebody on like way I don't even know The other Dr. Phil. Yes, like so long ago. Oh, he wasn't a doctor. He was phil donahue. My bad it was the Phil Donahue show.I put two generations together. Anyway, a long time ago probably in that Which one had the mustache? Donahue? No, they both do right? Did Donahue have one?Did Donahue have one?I don't think Donahue had one.He just had white hair at the age of 20They were talking about it wheat allergy and I can remember thinking well, who would be allergic to bread like it was so not in our consciousness. You know, like I just what and with her with her colic. I was I remember for me, I was eating a lot of eggs and lot of dairy because food is good for you. Right? And, and I ate a lot because I was nursing her. And I kind of cut it out for a week and she got better. I thought, well, it can't be that. So I didn't keep it going. Because it just never they that was 1982 and three Like it are three and four. They just they weren't talking about this stuff back then. I mean they were but it was, you know, there were some diagnosed cases of celiac disease than as there were, you know, in the 20s. And earlier but not, not in the mainstream.I would say people that still don't quite understand the seriousness that can happen from high gluten exposure to people that have celiac disease, they still dismiss it as it not being a real thing,Right. There are patients with celiac disease who dismiss it as not being a real thing. 'm sure you see it often. They'll be like, Well, last week, I just say whatever I wanted. And I don't even feel bad. I'm like, well, then you must have asymptomatic celiac disease, but your gut hates you. Right? Right. I mean, I don't tell them that but that's what I think.So everybody has a story about their gluten and I mentioned mine so my researcher that helped me develop Atrantil. So, you know, our whole thing with Brandi was that she was working for me and she had enamel problems she kept going to the dentist and having teeth issues. And then we were going to enroll her in a study and her liver Tests were up. And she was in she was sick and she had his weird rashes and she'd been worked up she was came from Iowa where the Iowa doctor said, Oh, you're fine, it's IBS. It's all fine. And then we're trying to enroll her in the study she had increased liver tests, ended up testing or figuring out she has celiac disease. So then I, out of courtesy, after we diagnosis, she started feeling better, I would go to lunch with her and I'd be gluten free, I wouldn't have these other issues. So and I checked myself with my least blood test, I don't have celiac but then I just started thinking, Wait a minute, this whole concept of gluten you can call whatever you want gluten sensitivity, gluten intolerance, all the other things. So when you say that the spectrum, and anybody that's listening to this, it says you know I have celiac disease, but I cheat all the time. Well, you have the risk of developing all kinds of stuff. lymphoma, you have the risk of developing osteoporosis you may not be running to the bathroom all the time. You may end up with UV itis which is an infection in the eye. This can trigger and Here's the biggest thing that I tell all my patients, you have one autoimmune disease. Now you are at risk for every other autoimmune disease, we have to control the one right so that you don't end up with thyroiditis, autoimmune hepatitis, ankylosing spondylitis, and all these others. So when people come into your store, and they're like, yeah, yeah, I like your cupcakes. But I have celiac that I don't tolerate it. My answer to everyone that I talked to is do you want lymphoma? Do you want to develop ankylosing spondylitis? And now we're seeing in the future, that if people carry this, it leads to inflammation, we know that inflammation leads to dimensia, things like that. So protect the gut, protect your body.But people will come to that in their own time in their own way. You know, you can't I don't preach gluten. Well, we obviously don't. I mean, we're not doctors. We're not offering medical advice in our stores. They ask our experience and what we've seen from our customers and we give them you know, stories and tales of what has helped us or some of our other customers, but we're obviously not going to tell them well What we may do is say, Well, you know, we have an awesome pizza crust that you can take home and make your life easier to where you don't feel like you need to order out. And you can still stay gluten free. We tried to just let them know about the options we have, because it is very challenging. I mean, I think my mom and my sister and myself approach being gluten free from a perspective that not everyone does. I think we looked at and we're like, Huh, well, celiac disease, probably probably the best disease you can have. It's completely manageable. It doesn't give you bad side effects if you do it properly. And it's not that difficult to wrap your brain around, doing it properly, at least from how we approached it. I mean, you have to accept that it is what it is. and food is medicine to us. Right. Solet's look at it beyond and not being the worst disease. You turned it into a pillar of a great business. Yeah, but But even before we didn't do this for about four years like, one guy came in he goes, isn't this the worst thing that ever happened to you? And I said, No. I said long before we started this company. No, it was the best thing Because look at what it did. I mean, I was what I thought was just super healthy 48 year old like I was, I was in great shape went off a gluten and I was 20 within two weeksI mean you weren't you still shad fibromyalgia and other things and joint pain. It all went away.Well once you were gluten free Yea. Yeah. right but i mean i think relatively speaking at 48 compared to other 48 year olds, I was remarkably healthy and then and I thought it was just age I'm like, Oh, I'm aging wasn't aging at all to heck with that.So why why would you eat something that making making you sick? Yeah, yeah, you know, I try not to.As I drink my Dr. Pepper still every now and then.I mean, I know we will talk about that. We're gonna get into that. There's a there was a podcast that I like to listen to as a as entrepreneurs as people podcast called how I built this.Love it. I want to know how you guys built thisAwesome. So my background. So my grandfather, mom's dad had a franchise of restaurants that he started in late 50s that he became a franchisee for in the late 50's. So restaurants are sort of in our blood, but never something I thought I wanted to do. Restaurant hours were not something I had an interest in. I've been there done. I studied finance and accounting and I used to do litigation consulting. It was what brought me to Dallas. She came to Dallas shortly after I did. My sister graduated was, you know, off at college and beyond. So she moved. And well got out. I hated my job. I did not hate my job. She denied her job, but it was grueling and I hated my job and I'd always begged and what was your job? I came down here as a banker I'd been working with my dad had been a stockbroker, previously I have an econ degree. But I hated my bank job that brought me to Texas but I loved that I came to Texas and I was like, I'd rather die than keep this job like I've got to do something different. And so she began making these food bars for Erin in college because Erin's now celiac and needs food grab and go food well back then If you believe it it was before there were bars on the marketYou were making the bars?For my sister. i always cooked.So she was making food bars She was tired of just eating you know, nuts and dried fruit juices all she had available. This was years ago so Lara bar did not exist. So she Taylor then she packages them and gets this cute little gold T and then she puts a label on the back and I was like, and then she gives him to people as wedding gifts as well. What's it called? I don't know whatever get all. Yeah, so then I said what it was my idea to start a bakery She goes, we'll do it. Because if you don't, I'm going to do this. And I was just terrified to bake I had tried several recipes and they had just failed miserably. One day I did like four different recipes of cornbread and a several recipes of brownies and they were just the worst things ever. And I've been baking since I was little and I have been throwing away food since like 1963 or something. So anyway, I was like fine, I will learn how to bake so I just really jumped into it started reading about the different properties of the different flowers. Different flowers have different properties. And I figured out about some blends by looking like stealing some recipe ideas from a lady. And then I took that recipe and I morphed it and took some of the ingredients out. And then we just started baking, I made some bread that I thought would work and it worked. And it was a great So we we adapted old family recipes that were passed down from grandmother's that she had quick breads and dinner breads and things like that and just adjusted them to being gluten free and dairy free. Once we figured out how to do the flowersI've always been dairy free and dairy free since I was diagnosed dairy free at like, you know, eight months. So we started adjusting all the recipes, and we realized, hey so you're able to take old family recipes and convert them.That's exactly how we did it. Our first 19 recipes. Were family recipes. They were sort of our original, we still have almost all of them. That's nice.That is so cool. There's legacy in this there's tradition. That is awesome.Like my mother baked her mother baked her mother like it's just been my whole mother's whole side or huge bakers and then my dad's side are super bright, smart. Academic kind of people. And it just works. She and I are kind of the combination of both sides, which is I actually don't like to bake, which is comedy considering it's my business in fact. I love. I love helping people and I love serving others. And I love our product. And I love what we stand for. But you're the nutrition side. Yeah. And I like to make everything healthier. And that's definitely of interest to me and always has been so she took family recipes, and then I would adjust it, we would make it vegan or we would cut the sugar we would increase you know, whatever it is that we were doing. So I would make sure that it tastes like if it didn't taste good. Like it had to be good and gluten free first. And then if we could decrease, we could take out the dairy. And she got she was so good at it that nothing has dairy in it anymore, but we just got great at taking the dairy out, but it and then we lowered the sugar significantly. But if it doesn't taste good, you're not going to eat it. So there's that balance of Yes, it's gluten and soy and dairy and corn free and 50% less sugar and it's organic, but does it taste good? And so you have to draw that line and having Enough sugar that is still palatable while knowing that you don't want people living on sugar. So we're really good yin and yang of making sure that the nutrition is is acceptable. While it's still really satisfying. Optimal while edible.Yeah. Could be a T shirt and find optimal while edible. Edible while we will. Yeah, sure. So we started we started just the two of usWhat year was that? August 2010. Well, March March, we started subleasing space of 2010. January through March, we sort of worked on the website, ordered labels, things, things of that nature. You did what I'm sorry? Our first customer came in and we literally went, so we were subleasing. 6 days a month. So...We were subleasing space from him. She would like a private chef. He did South Beach diet. I mean, this is a long time ago. I don't even think it's still a thing. I mean, nobody even knows what that is today. But so she was she wasn't a gluten free facility. But she was. I mean, it was She was free because she was happy. She didn't do any grains. So we sublease space from her one day a week and then two weeks, Every other Friday, Two days. So six days a month is when we started. And that was the end of March of 2010. I think the second week we were there as somebody walked in. Yeah. This tall thin guy and we're like, but he's like, I this is this where I can buy gluten free products. And we were like, what? How did you find? I mean, we have a website but..Let's back up a little bit. I'm super into how businesses are built. So are you guys sitting in your kitchen, making this stuff together and then taking it to this place?I was in my kitchen doing most of our recipes and she was in her kitchen doing the food bar and we honestly thought the food bars were going to take off and that the other stuff wasn't because she found outlets. She sent food bars or hand delivered food bars to a lot of people they weren't podcast back then no food blogs, food blogs, so she wouldn't in a food blog situation for I don't know 15 years, right. So we did That and then we did. We went to a celiac support group in Dallas and then we went to one in Fort Worth or North Richland hills North Richland hills, and brought our food. And at one of those two interesting things happen there. The first question they asked was, are you soy free? And we're like, Huh, am she and I never had had an issue with soy and really weren't paying attention to things besides dairy and gluten. And we're like well no but we can be because it happened in both groups that we met with, so we figured it must be important. And then at one of the meetings, a blogger for the Dallas Morning News, mom's blog was at one of the meetings. So then she came to us and asked if she could interview us, and she's celiac. Nice. Yeah, she's celiac. So she came in, she interviewed us and did a story in the Dallas Morning News, moms blog, which got maybe the most hits they'd ever gotten on a story, That's what they said comments. It had like 80 comments on the story. So then Nancy Chernin with the Dallas Morning News. Well Hold up. So we were baking in our original kitchen separate on our very own kitchens, we had already quit our jobs. We quit our jobs at the end of 2009.Is that was that a real difficult decision? You no, because you wanted it out was this for you? So I got married the end of August Excuse me, I'm sorry.You can always a hit that we have little we have Eric and I always do that. Sometimes.So you didn't you didn't teach me that? Now, I know I was so much more interested in the history quiz.So I got married august of 2009. And I quit my job in November, I think in my husband like August 29. So I mean, we're talking like a month later. And my husband's like, Yeah, I am. I'm not sure if I've married a banker. Like last I checked, he were doing litigation consulting. What happened to that? Yeah, but your hours were horrific.No they were there was it wasn't something we wanted. It wasn't sustainable to have a family. So you know, I quit my lucrative job. And now I'm an entrepreneur and I work all the time. So It's even better, Make less money and work all the time. But I love it so and it does it. It fills meDo you think like you're helping more people suing them or feeding them good food?Undoubtedly we are making a huge difference in people's lives. And it's awesome. So we baked in our own kitchens, yada yada, yada. end of March we started subleasing space. That blog came out maybe in April?It came out was super, super soon, Super quick. I mean, we tried to put ourselves out there but this is kind of this is before social media. I mean, Facebook existed, but it was like a college. But you know, it wasn't even for the general public. So it was a totally different situation. Which is even hard to believe today. But so then, in June, the people we are subleasing space from No, no, no, we came out in the Dallas Morning News on a Sunday on the back page of the Sunday edition of the of the whatever you open the newspaper up and we're the were the full page on the back page, titled building a better bakery like i'll never forget it. On that Tuesday, we sell out Oh my god, people were so excited. Wednesday they tell the lady releasing from that she loses her lease. And we're like, what? They won't let us put a note on the door. And so suddenly she's closed. Luckily, we had already at leased a second space. We had seen the success already. And we're like, okay, we just want to we can do this. So we were Yeah, we wanted to just prove ourselves. So we were baking one day a week, we would bake, we would freeze. And we were so tired. Do you remember, we were so tired. We thought it was so hard. It was all it was. And so then we we went ahead and signed the lease and started started construction and all of that on our first location. And then we lost our sublease because they lost their lease the day after we came out in the Dallas Morning News, crazy. And we and we were closed for two months, because we had nowhere to go. So the timing was awesome.This is like with Atrantil we get knocked off. Yeah, we've been like knocked off Google after we did like a big podcast and you're like, Oh, look at that. Everyone's looking for us and you can't find us.Yeah, wonderful.I remember years. years later, somebody came in and said, Oh my god, you're still in business. We just assumed that you'd gone out because it happens all the time in new startups, and especially like there have been several gluten free bakeries that have started and stopped. And it's, you know, starting your own company is there's nothing easy about it. It's not easy. Definitely no easy. There's no rules. So we opened our we opened our first what we call our flagship, it was called White Rock. We used to bake there, and we had a retail presence. We were open Tuesday through Friday. No, Tuesday, Wednesday, Thursday, at first We're like we have a specialtyJust You two?Yes. Still?We might have hired one person by then our first girl was Anna, who came back us after 3 culinary degrees. Anna is still with us and we love her.She came back to us. Wow. I know she's massively overqualified. But she's awesome.But it was us for quite a bit and then Anna came on and then we gradually started just hiring people. And then a year later, we doubled that space. We took over the lease next door and expanded ourselves. So then we had, you know, more retail, more seatingThat's when we add coffees and tea's and smoothies and sandwiches.We doubled our freezer capacity so something we do which is no secret within about an hour of production every product we make is frozen. It's packaged and frozen. So gluten free products on the market are sold frozen This is no mystery. If it's not sold frozen then it has a lot of stabilizers in it which is not something we believe in so we don't do that.say that one more time because...So if it's sitting on a shelf...It's full of junk. It has a lot of stabilizers in it. stabilizers preservatives chemicals bread is bread, you know bakery sell day old bread, bread is not meant to sit around for weeks because it's it molds it has or it gets dry and it's hard and nasty they sell and they sell daily bread for a reason. day old so we freeze all of our product as soon as it's cooled so it's perfect for you. It to enjoy for you know we say a year. I've definitely found product in my freezer from several years before that that we consume in my home. Now do I say that to our customers should you eat your product three years later? I mean do what you want. We say it's great for a year. So, but we freeze all of our products so by then we needed another freezer so we doubled our space. And then... Sure. From a business perspective, sorry to interrupt but I love the idea of the entrepreneurship. No No, no, I just, it's as somebody who's an entrepreneur that is in the throes of it I just bogged down by the like, I want to know like what the relationship was, did you have to have somebody analyze the food after a year to say this is safe for a year.No, we did our own I'll take this part when we we used to bake something we would put it on the counter, we'd wrap it and put it on the counter, we'd put it in the fridge and we put it in the freezer, we would date it and then we would watch to see how how it landed you know and see how long it stayed soft and whatever on the counter and it always got hard long before it molded. Now like now, a sweet bread pumpkin banana bread. It'll mold before it gets hard because it's so moist, but we figured out how it would hold. And that's how we know like we found something in my freezer three and a half years later that was dated and we knocked the ice off of it and ate it and it was amazing. It's just sort of a interesting trial personally i mean but we did so we haven't had anything like we're not gluten free certified because we're dedicated gluten free and like who was it that said well I mean they say they are. We've just developed this reputation where people know that if we say it's this then they believe it is. But we also don't have cross contamination in our space with gluten and soy. It doesn't exist. It's dedicated. we built out. It used to be like a retail facility that is our production facility. And every product we buy is a certified gluten free product and by product i mean a raw gradient like organic brown rice flour, organic almond meal, like these things are already certified gluten free on their own, and that's everything we purchase. And we're in dedicated gluten free facility and what most people don't understand these certifications for organic or non GMO or or gluten free our per product they're not..I was gonna have eric comment on this because this is the stuff we would would you just tell the audience really quick, so you don't have gluten free stamp on it. And there's a reason you don't have the non GMO paleo friendly keto. explain to the audience what these mean, You have to pay a license to even have those monitors applied to your label Per product. And then some of them if it's what does it do the wheat foundation of celiac Foundation, not only do you pay the license fee, you pay 1% of all of your sales on top of that, because they..I mean it's prohibitive for us,especially, especially with the number of products we have if we if we were just trying to distribute five products across the US. Absolutely, they would be certified gluten free. And if and when we ever go that direction, they will be as well. However, am I going to certify all 15 types of cupcakes we sell on a daily basis? Absolutely not. Or all 8 sandwich breads.We're a dedicated gluten free facility. We will never have an issue of cross contamination with gluten, gluten, it's never going to exist or happen and we have literally Not had an issue with customers caring about that. Yeah, you know what I mean? Or getting sick? Well, they never could get so we only purchase certified gluten free raw ingredients like it. We have strict protocol, we have signage it on our doors that asks you to not bring in gluten containing items into our stores. We ask customers to leave Sure. Yeah. That's awesome. Because of customers are sitting there at one of our kids tables, and they Oh, and they are their kids might not be gluten free, but they open a package of goldfish. It's going to make my next customer sick. So... And it could make somebody like we're like, it would just make me sick for a couple of weeks. But it might it could send somebody to the ER like people can have huge reactions to it. So we just ask people to be respectful and they absolutely are. I mean, they look we have people especially in some of our center, our locations that have like sort of a real walkability factor. If they're coming in with a sandwich as they're walking and shopping. We'll just politely ask them to leave it outside because we're gluten free facility and we take it very seriously our cars our staff cannot eat outside lunch.So I just want to say One thing that I love the fact that your reputation precedes you and you are above these, these different labels and stamps and things like that, but these labels and stamps had to come about because people were skirting the system and they were lying. And that's what the supplement industry and that's what the food industry will do. So another industry was built upon it so that they could at least monitor it and you guys are like, No, we got it figured out.Every so often they share facility right? Most people don't build out their own production facility. So some gluten free cracker on the market is being made and another packed cracker distribution facility. So they have to test for parts per million because they're using the same machinery because that machinery is hundreds of thousands, if not millions of dollars. So they go through a rapid cleaning process, whatever they do, and then they test parts per million to make sure it's under 10 to certified gluten free because it's on shared equipment. That's that's not something we're dealing Right because we're our own facility. I would also say that I'm not sure that I think that people are skirting the system or lying. I think that like if I'm let's say we don't have this great business and I'm wanting to buy gluten free stuff because my kids are super sick I probably wouldn't have done it for me but I would actually do it for my children right which is a lot of what we see at our stores is that's for the their kids often. I would I would need something that said it was certified because Am I going to trust blow Joe from you know, whatever town in some state that I can't get to, you know, we've earned this reputation because we grew organically pardon the pun, from area to area to area within the DFW area. So we're still in a small area even as we ship nationwide. But I also think there's a lot of trust within that dedicated gluten free facility I believe somwhere that's dedicated gluten free. Definitely. I will not eat a cupcake from somewhere that just sells a gluten free cupcake. Nope. Because it's probably next to the gluten cupcake.I've been burned on it so many times. You should see what our facility looks like. Like we've built out a dedicated room in our facility now to do the mixing because flour goes everywhere. And after one recipe, there is a...There's just a shrowd of flour all over everything within within Oh 20-30 feet Her point to that is that if it's a traditional bakery they're getting that flour everywhere you can't you can't all of ours are gluten free so we do it for cleanliness and right various other things. What did you get out of the machinery? You'll find gluten everywhere. Everywhere. It just it just goes up in the air. You can't help it. Like, people sometimes get upset that we have sprinkles, right? But some kids they can eat it so it's no trouble so if they can't eat gluten, soy, dairy, corn, eggs, peanuts, tree nuts, but they can eat our cookie and our cake. And they want to feel like a kid by having sprinkles on it because you know, Sally gets sprinkles on her cake from whatever bakery. By golly, we're gonna have sprinkles. It's not going to cross contaminate. Just don't we won't get sprinkles on your stuff like it's okay. But gluten and it flies. It flies. Yeah. So ya'll have the first store and it's now August 2009. We've gone...2010.2010 and then suddenly, when did you start to realize hey, we've got something successful. And we might even grow to a point where we have more than one location. We knew it from the get go.Right. So I think it's more of could we keep up? Oh Okay, So we knew that the demand was there immediately. Sure. So we doubled up our location, we built up a triple size freezer than what we initially had. This is at the White Rock location?And then as soon as we doubled up White Rock, we then were like, okay, a lot of our customers are coming from the north.Hour and a half away. Why are people driving from so far north from McKinney, Frisco? You know, now it's little Elm and prosper, but then it was like Alan,Richardson, McKinney, Frisco. So we started looking up north, and we opened our Frisco store in September of 2013. So it was our second location. Now we'd already doubled our initial location, but it was our second location. And then we opened. We opened our third location in November of 2013. But that was unusual. He would traditionally never open a store that quickly Back to back But now we've done that two more times. Not two months apart. Yeah, we did we opened medallion in in March and we opened Fort Worth in in June. So are you guys? Are you are you all self financing this whole time? We are that we're all self funded.So that is that's bold.Impressive and awesome. We are crazy. I like to say we are just crazy.That's part of what that's part of what our I wouldn't say delay, but it's not like we have immediately bombarded the whole market, but we see companies do this all the time. And it happens constantly, especially in this healthy eating space. There's multiple name brands that you can look at across DFW that have done this they have popped up 25 stores and they close 22 of them close in three years so it's happened time and again in this healthy eating space. I mean happens at restaurants especially but in retailWhen you expand it just out of curiosity obviously going from whiterock up to the Plano Frisco McKinney area probably made sense because you could tell what People were driving from like you said.Plus we were trying to spread it out. We didn't want to monopolize ourselves within a doable distance. Like we didn't go to Austin because it would have been too hard to control.I understand,You know, but we felt like we could control from and whiterockrock to Frisco and we could. And we didn't feel like the Frisco market would cannibalize our White Rock store either. So that was our initial goal in our growth kind of market and we looked at some of these other healthy eating space brands that have popped up all over and we looked at where they were and we looked at where our customers are coming from, do we pay and have studies completed? No, we didn't. But we looked at our our customer base and where we would want to shop because we are our own customer.That's interesting, because there's there's a friend of mine from my hometown and he started taco casa. And the way he decided on where he allows people to have a franchise and open up the places he will look for a taco bell and or a McDonald's and then see what the traffic is.They've already done their due diligence.So I'm thinking your store in fort worth if I remember right is on Hulen. Yes. Is that correct?It's underneath Central Market.Yeah. So not far from Central market, but it would make sense off of hulen to be in a place, so is that kind of how you piece that together because your Frisco location makes sense.We grew up in the business, we've watched, I've gone with my dad to look at site selection with the National franchise group. So we and she grew up running the stores. So we kind of knew the brains behind that. But also, we're a destination location, whereas most restaurants are not most restaurants. It's a cluster location, but we're more of a destination. We're very unique so that that's why we could open up our first location was probably in an ABCD spectrum. It was probably a D location or a C location. I think it was it was technically classified as a C location. But it didn't matterLike never like today, we would never put a location in aC location, but it was our original and our Flagship. There are things that we look forward to had parking, which is a huge thing to us, like Parking is huge for us are, you know, soccer moms are a huge part of our clients. Oh, I am my own clientele. My kids are both gluten free. So I just want to comment on this because you said something really cool. We could have paid the money to have market analysis, but we knew who our clients were,We know our customers. We are our customers. So that's we have we have baked for ourselves the entire time, which I also think is why the quality is different than most gluten free places. We'd literally eat our own food. And if I don't like it if I don't like it, we don't make it.Love that.Because I've got she calls me a super taster. Like, it's gotta have enough sugar but not to much. It's actually really annoying. But it's great and you know, both sides. Yeah, I just asked if it doesn't taste good. Why are you going to eat it like it's baked food is comfort food. It makes you feel good. Like the first gluten free bread I had after we got diagnosed was a I'm just Can I say that? No, don't say the brand. It was a white hamburger bun. See look I filtered filtered. That has never happened. Put it on the calendar. Never happened. It was a hamburger bun that was shelf stable for a year and it was on the counter. And it was just like almost like eating styrofoam. How delicious Do you think that was? Not very. You know, and I was like, so we didn't eat bread like I literally none of us ate bread till we really started baking because we just let it go. Because it wasn't worth the calories like to me like carbs are a happy calorie and if it doesn't taste good, then why are you going to eat it? But it's true, like we will dine out and my kids will say I'll ask them all ,buddies. Do you guys want a hamburger bun today? And my oldest boy, he'll say, well, who makes it? Who what brand is it? And he's like, discerning He's like, well if it's that bad I want that one. He doesn't want to he doesn't like it. It's not his it's not it's just not worth the calories. Well, that's not how a 9 year old thinks. That's not how he says it but that's what he's thinking it's just not worth it. He's like, I don't like it. I'd rather have more french fries. So he's already made but he's making those choices without knowing that he's making those choices. By right we so back to your did we pay for market analysis but we're also not necessarily answering to anyone either. We are we are our board of directors we are bank we are loving we have the ability to make those decisions where you know the larger companies they might have to answer to their investors or whoever else andWell they would have to. Right this is why they want to put something somewhere and this shows that.So when I when I read about different successful companies one that comes always pops into my head is Southwest Airlines. And the CEO you know the name of the CEO I always forget. Gary Kelly. Just keep her around. She knows everything.It's a because we have to deal with this real like you cannot please everybody. And it's the whole story where a woman was complaining and would send an emails about how she didn't like this, this and this, which are all standards for Southwest like you're gonna wait. You're going to get in Group A, B or C. And he wrote back. Thank you for being our customer. We hope you enjoy the next airline you fly. Basically we're not catering. This is who we are. You don't have to cater The people that want to come to unrefined bakery, they know what they're going to get. They don't need a stamp on it. And you built this with your model with your convictions with your money and so you don't answer to anybody. And you can do this unapologetically. If somebody says that the super taster did a bad job tasting doesn't matter, she's the super taster. There you go. But, but on the flip side of that we do very much listen to our customers. And that I think has been probably our most pivotal point of our success, right, is that we listen to what our customers want. Do we listen to their complaints? I answered them all personally, She doesn't let me come close to those. Every single one of them. We have very, very few complaints are our customers love us people cry in our store. It's actually part of our training for Front of House staff is how to deal with the crying mom, because it happens. Really? All the time. weekly in every store.Give me an example of how that would go down.Okay, I wanna give one. Sure you give one and i'll give one. A lady comes in years ago her husband's with her she's got, it's from when we were in White Rock, but you can repeat this like every week in the store.Every week. Yeah. Kids in tow and they're all like got Cheshire Cat grins and she walks in and she goes, What's gluten free? Happens all the time. We said everything. And her husband and kids knew that she didn't know it was like their gift surprise to her. And they brought her because she I'm gonna cry. And she just started crying. She did. And normally it's the parent crying for the kid. But this was the mom that was celiac. And the family had done this for her and brought her to us. And it's just, it's why we do what we do. Like it's why it's why we've grown. It's why we've put the money back into the business to get into the market as best we could to make sure that we'd be successful. Because if we didn't grow like we did, somebody else would have come in and grown People have come in and some people have already left. But we needed to saturate the market as best we could with our own limited funds. Because we we think we're the best in the country. What we do, we're we're organic, we pay attention to the ingredients we do as little sugars we can't we do as the least harm that we can with the best ingredients that we can to bring you the best product that we can. And I think that we succeed. I mean, I think it's good food.As a customer, I could say, I trust everything that you're saying delicious.And we really care, We won't ever make sacrifices in terms of the quality of our ingredients. If anything we have we not acknowledging we have simply improved the quality of our ingredients. We never started being as organic as we are. We're basically 98% organic. There you know We started off being about 50 or 60%. Like when they were kids, I tried to buy healthy food as best I could within the realm of what I knew back then. We started off being gluten free and then immediately went soy free, and then quickly started taking the corn out because people say can you take the corn out? And we're like, well, even and we didn't even use organic corn at first. And then we're like, well, we can use an organic corn. But even then it's just a starch and doesn't really add value. So what's causing people trouble? But it just snowballs. I mean, the more you The more we know the better we do. Like that's how we have grown And we're better at making recipes now like everything's better.How hard is it to when somebody says can you do something without soy I can do something without corn? How hard is it to redo these recipes, the familial recipes. Oh it's hard.it was very hard but it's it's complete. So we're not there's nothing more to change at this point. Today we we've kind of focused more on growing our Kido line that's been our largest so these days not only are we a gluten free bakery, and and, you know, an allergen bakery in general that's sort of how we're known but we're also known for just catering to special diets. Whether that's and I don't mean diet isn't Oh, you're on a diet. I mean, diet is in this is how you fuel your body. So whether keto,vegan,paleo, those are all diets, we cater to tremendously vegan because by eliminating dairy and eggs, such common food allergies, we have vegan products, and then keto because we already it's difficult keto baking is intrinsically Difficult as is paleo baking paleo baking is easier than keto baking. We need to back up paleo baking is no grains, no sugar, no dairy, no legumes. Keto takes it further they don't want even this sugar from say the bananas that we would use in a paleo muffin to sweeten so they want an alcohol sugar to replace the sweetener. So the body doesn't take it as a sugar and they want and no starch And no starch so you can't use the tapioca or era root. 20 total carbs per day.So you're baking predominantly with eggs and seeds, nuts and seeds and a lot of people do keto in a very 1990 Atkins way where they're supplementing with cream cheese and other things that they're baking with but our keto was all organic and dairy free, which is highly unusual Super hard because when I tried keto it was basically do cheesy eggs in the morning cheesy eggs for lunch and cheesy eggs for dinner.Butter bombs, you know, little butters cream cheese and don't eat too much avocado because you know it has too many carbs.You have to Be really careful. It's awesome because what I Hearing though is you're meeting your customer where they're at but doing it with your standards. That's exactly right. We we know that...We won't change our stores. Yeah, our people come here. And I hear that you're wanting this. We're going to try to meet you. But we're going to do it this way in the most ethical way possible. I think it's fantastic. Somebody said to me, Well, I had a keynote cupcakes the other day, and it was better than yours. I was like, that's awesome. That's great. And, and they emailed me the ingredients to it, because they thought we should make it and I was like, well, none of we don't use these ingredients. We you can't even pronounce these ingredients like this is not this is this does not meet, unrefined's way of doing anything. It's not organic pastured eggs, it's I mean, we're just not going to sacrifice our kind of core competencies and core beliefs to make a product that she thought was more palatable. She's Welcome to buy their cupcakes And just to clarify, the reason we do it that way is because we really think that the the junk in the food The reason it's called junk, you know, the chemicals and preservatives, the additives, the colorings, all that stuff, we believe to our core That that is part and parcel of why people are getting so sick. It's not just the gluten and it's not just the dairy. It's not just the sugar. It's the combination of all of that junk. I couldn't agree more.Well, I mean, so everybody sits in so I get this all the time where patients will will tell me Oh, yeah, I don't know, I feel a little sick when I have gluten, but I know that's just a thing that doesn't really exist. And you start looking at Okay, it's not just the gluten. It's the amylase trypsin inhibitor that's there that the that's the GMO wheat that allows it to be pesticide free. Now we know that creates intestinal inflammation. That's a very simple thing. Now we know I had a patient today where she was talking about being bloated and she had her pocketbook out and a protein bar was sitting right there. And I was like, do you mind if I look at this and I pulled sugar alcohols Winner Winner it said no, it said non dairy, non gluten but it was making her bloated like crazy sugar alcohol. That's awesome for your gut. Yeah. Exactly and then yeah, and so it's it's funny, you're exactly right once it gets put in a package can sit for a year on a shelf. There's all different kinds of things going on with this.So y'all, y'all are y'all just opened your seventh location? Seventh retail locations. Seventh retail location. And ya'll also do special packaging and shipping for people who are on the contiguous 48. Yeah, yeah, we shipped to all 48 lower states. You know, the 48 contiguous. Yep. And then we also have a pretty large wholesale businessHold on and one special customer in Alaska. I'll just say one special shout out to my sonMy brother lives in Alaska.We used to ship him cookies in Iraq so Yeah we did Alaska is nothing compared to Iraq.Wow, that's fantastic. Y'all do cold pack shipping i guess?So we ship with dry ice across the US, but it's not required for everything. So some of our products especially locally within like a UPS ground delivery system within a day, which is Texas, Oklahoma, Louisiana, Arkansas, I mean a pretty good chunk of the regional US that we're in is next day so most of our products can ship next day no problem I mean we asked for you to freeze them to prolong shelf life and but they're not going to go bad in a day so a lot of people opt against the dry ice shipping but then things like our cakes and our cookies we require dry ice shipping for sure. So a lot of people add that plus their breads and other things to their cart and checkout. Or pies. Yeah, we ship our piesPies are fantastic By the way Can you giveme since I've met Eric his seasoned with your stores, but I've not been into one of yours which I'm going to do probably tomorrow. Can you tell me that that you'd like a brief list of the types of products that you carry or that you make?Yep. So when you walk into our stores, we kind of act as though the freezer section of the grocery store you shop at whether it's central market or whole foods or Kroger or anywhere else. You look in the freezer section of the gluten free staples you have your sandwich breads your dinner breads, your hamburger and hot dog buns all your various muffins and your pizza crustpizza crust is in our top three most popular products Pies. I meanY'all have dough's too. we do. Pie dough and cookie dough. Pie dough and cookie dough cookie dough so we I like to say we make everything gluten free with exception of pasta and crackers. So pasta and crackers are not items we make nor will we make people like oh you should make that I'm like why never made it before I'm I don't have the equipment for it. We stick with our with it our expertiseSo pasta and crackers are never going to be something in our wheelhouse it just doesn't work with our model but anything baked whether it's quick breads or you know and then obviously all of our cupcakes and cookies and custom cakes, custom cakes are huge for usCustom cakes?Anything like 50% of our sales. No kidding Shut the front door.That is that is so labor intensive.Well it is but our but where else are they going to get a gluten free dairy free soy free corn free peanut free tree nut free. Where else are they going to get a cake that tast tjhat good and that every recipes a custom recipe for that item like not like we use a mix. Like every recipe is different. Do you go so far seems like wedding cakes and stuff like that? We do. Absolutely.Wow you guys do not hold back.That is all her area I make it taste good and she helps people make it pretty.So we have a cool thing that are you know unrefined loyalist follow for us. We have our cupcake of the week or our cow as we affectionately call it the launches every Friday. I believe this is the Cult following seventh year we've done cow. So we've been doing every week for seven years, a new cupcake of the week, launches every Friday morning at 9am on social media, and then it hits all of our stores that day, whatever time they open, and they last until it sells out and it's always a custom flavor. And we bring back our favorites like what's today, Thursday. Tomorrow, Oh no! First time ever.Oh wait. Is this like an early leak late for the cow.Tomorrow's our cookie monster will go nuts for so it's like a chocolate chip cake and it's filled with a chocolate chip cookie cream and it has a whipped vanilla buttercream to with chocolate chip cookie crumbles. And its people just love it. You are going there tomorrow.Oh yeah.The best one is the overload the chocolate overload which is my favorite.Chocolate over it. So we have like probably five most requested cows, the overloads one of them, it's a chocolate cake. It has our fudge brownie bakes into the center. And so it kind of is gooey and then crispy on the top. And then it's topped with ch

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A Surgeons Guide to a Plant Based Diet

Play Episode Listen Later Jan 23, 2020 83:06

Remember, I am a real doctor Eric is a real crna. We do do real medicine. But this show is not intended to diagnose or treat. Please, if you have any issues like rectal bleeding, go to our website, kbmdhealth.com. Download the E book, learn about it, but make sure that you talk to your doctor about it.Ken Brown All right, here we are with the gut check project, Episode 29 a super special episode because we have a guest co host, Eric Rieger was unavailable. And so we had a guest co host today it is Dr. Doug Won, who's here. Welcome to the studio, my friend.Dr. Won Thank you so much for having me here. Truly an honor.Ken Brown Well, I think that this is gonna be a really really cool show. You're doing A lot of functional things you're really big into treating the whole person. Your background, I think is really cool. I am gonna warn you though. I hope you're a pretty smart guy because Eric's a smart guy. You got some big shoes to fill in. So why don't we at least find out like if you're, you know, like where you actually came from and everything. Tell us a little bit about yourself?Dr. Won Sure. I'm from South Korea, immigrated to Irving, Texas when I was 11 years old and went to elementary, middle school and high school in Irving MacArthur High School, go Cardinals. And then after that, I went to Northwestern University. I majored in biology and biomedical engineering, and then went to medical school at utmb in Galveston, and once I was done with the medical school, pursued orthopedic surgery at Washington University in St. Louis, and did spine surgery fellowship in Michigan, and then came right back to Irving, Texas, to treat my friends and family members and my local community and Irving, the city that I love, I went back to it and been there ever since.Ken Brown Yeah, you're way smarter than Eric. Yeah. Of course right now he's probably arguing I didn't hear anything about Texas Tech. So you know, so in his mind, you didn't go to Texas Tech. You're not nearly as smart. But I guess you did say a few other things Northwestern, double major biology, biomedical engineering and everything. So, yeah, I think that I think the show is going to be really great. What I want to do with this show today, you have you and I have very similar passions. We're really big into the functional medicine side of things. I want to cover some anti aging stuff. I want to talk about how supplements and nutrients can actually augment a lot of these different things that talk about your past. Now. You are one of the most accomplished orthopedic spine surgeons and I can I have to pick your brain before we even jump in. I was actually talking to a very difficult patient of mine and I wanted to throw out a disease and just see if you've ever dealt with any of this. I believe That we have somebody who is smoldering into ankylosing spondylitis. Now this actually happened to one of our co workers, but now I'm treating somebody who's acting a lot like she did. She spent about two years just sort of, you knew something wasn't right. And then pow it just kind of all popped up. Have you had some experience with autoimmune diseases and stuff like that specifically as ankylosing spondylitis?Dr. Won Yeah, absolutely. In our spine clinic, we used to see a lot of patients with ankylosing spondylitis. And then also patients who didn't quite have the the conditions, but they were HLA 27 positive, and they were brewing the different types of symptoms and conditions. And then we also deal with because I also deal with lifestyle medicine. We've actually seen a lot of different kinds of patients with autoimmune disease. And what we usually tell patients is that your genetics and genes may load the gun, but you actually pulled the trigger through your nutrition and lifestyle.Ken Brown i like how you say that. Yeah, totally. So one of the things I just want to get this out of the way that you You're a very accomplished orthopedic surgeon. You're currently involved a little bit of a legal situation that you're appealing. What I think is amazing what you have done is because you have to put your surgical practice on hold for a little bit. Yes, you have shifted, and have still taken on the role of being a doctor, helping people and being an educator, you have not slowed down at all, you are the embodiment of resilience of moving through. I'm super, I think that's really, really neat. And why did you decide to kind of shift gears, I mean, you were going from scalpel. And I get that you have to take a little break from that. But a lot of people like you would just say, I'll use this as a break to go tour the world and say hi to things and you went I'm gonna use this as my opportunity to help more people.Dr. Won Thank you. You know, helping people and making a big impact was my passion. That is a reason why I went into medicine and went into medicine because you know, my father suffered from back and he had four back surgeries, and his life was ruined for about 30 years with severe pain and in life You come up with so many different challenges. Either you can crumble or or decide to just sit back, and then the life continue to punch you, or you can stand back, you know, stand up again, and continue to move on forward. And what got me going was as long as I can make an impact and help all the patients, and my passion was biohacking, which I've been doing, you know, all my life. And what I realized was that in medical school, we really didn't learn how to cure the disease. We learned to manage the disease. And through this experience, I really learned how to better manage and then in many incidences, and cure the patients, and wanted to continue to make an impact and help patients. That's what gets me going and that's what's getting me up every single morning. And no matter what anybody says, as long as I feel good about you know what I'm doing and continue to practice medicine in different way. Through health coaching, and, you know, even approaching and these days, I also teach a lot of doctors in Africa. How to treat chronic disease.Dr. Won You teach doctors in Africa?Dr. Won Yes. Ken Brown Okay. I got a segway out of that for a second. What? Tell me about that? Dr. Won Yeah, so I came in contact with a physician who was really into preventive medicine. He's a personal doctor to the president of Cameroon. In Africa right now, they're facing so many different chronic disease. In the past, before the Africa became developed, there was no such thing as heart disease, cancer, diabetes, or obesity. But as the countries are becoming wealthier, and countries are becoming more developed, they're now importing American disease such as heart disease, diabetes, cancer, Alzheimer's, and they obviously can't afford to treat the patients with American medicine. So they're looking for ways to treat the patients naturally, and also the citizens most of the people in Africa are still hesitant about Modern medicine. So we got in contact through a mutual friend. And we decided to teach the the physicians there, how to reverse the disease naturally. And then also importantly, to prevent them.Ken Brown Wow and so are you doing some sort of zoom with them? Do you have a lecture series? How are you doing this? Dr. Won Yeah. So every Saturday morning, I connect through them through zoom meeting. Thank goodness for technology. I don't have to physically be in Africa. I would love to visit the continent, sometime soon. When things free up, but utilizing the technology, we provide the lectures, mostly to physicians, but also just about anyone who's interested. And we open it up to the whole community. And at one point, we had people from seven different countries connecting seven different countries in Africa.Ken Brown Oh, wow. That is that is fantastic. So even before you had to kind of take this little hiatus from actually cutting on people and doing spine surgery, you've been thinking about this for a long time. You've been working towards the changing, changing the disease progress, you made a living for many years taking care of the end problem of people having wearing their bodies down, then you as the spine surgeon go in, and you take away their pain and you help them. But even then you were thinking, and what can we do to prevent this?Dr. Won Yes. Oh, absolutely. So we've been giving free seminars on how to prevent and reverse chronic disease naturally, for about three years. I initially did not necessarily want to give the seminars myself, I'm not a good public speaker. And so I wanted to set up the infrastructure and then invite one of the physicians to do it. And he did it in a couple of times, but it took him away from the family. And it takes a lot of effort to prepare different topics. So I thought this was so important. And as you know, when we're in medical school, maybe we had an hour or two hours of lectures of nutrition, and how to reverse the disease naturally. Well, actually, we didn't learn anything about how to reverse the disease naturally in medical school. We learn how to just manage the disease. And so once I saw the light, I said, I have to share this information with everyone as many people as possible Ken Brown Even as a gastroenterologist when I trained as a fellow, it is called the division of gastroenterology and nutrition. And I think we got like, half hour a week on nutrition. I know that it's supposed to a split the title. Gastroenterology and nutrition.Dr. Won Yeah. And look at the hospital. You know, once I had a patient after a very big surgery, and he had a mild, MI you know, mild heart attack. And the next morning when I went up to the patients for patient had eggs, bacon cheese, for breakfast and lunch, I said, this is wrong, and then go to any hospitals, whether it's Dallas or anywhere else, go to the cafeteria, the hospitals are serving disease causing food in the cafeteria and to the patients. I said this is wrong, right. That is the true crime. And I said, you know, it was one of our mission to to really empower the people and teach me How to Prevent and reverse the disease themselves.Ken Brown We should do a video where you actually come to my hospital to the doctors lounge. They give free food to the doctors and you walk around that doctors lounge. There's bags of m&ms. I've taken pictures of this. There's m&ms there's, this is really funny. There's actually bowls of like gummy bears. And I'll watch and people will just go by just grab a head. Start eating on the way out. I'm like, there's so many things wrong with that. Not just the food, but a lot of hands been in that bowl.Dr. Won Yeah, actually, I got in trouble with that one of the hospitals here locally in Dallas I actually took a picture of what they were serving at the doctors lounge and then post it on the social media. Oh, and then I got called into the principal's office. The hospital CEO.Ken Brown Oh, before we get called into the principal's office, since I'm not good at this part. This is what Eric does real well. One thing disclaimer both Dr. Won and myself are real doctors yet this is not intended to treat anybody or give any medical advice if you have that unusual rash or joint pain or anything, this is not here to cure or treat you. But this could help cure whatever it is or not, or at least reverse what's going on by lifestyle changes, not through medical advice. And the other thing that we always need to do is really give love to our sponsors. Our sponsors Atrantil my baby, my little polyphenol complex, which we're going to get into a lot of stuff about this because Dr. Won is a whole food plant based doctor. And those vegetables all have polyphenols similar to what we have, in Atrantil. And we do know that that actually can work like the Mediterranean diet, and do all different kinds of things. And of course, the KBMD health CBD, I'm a big fan of cannabadial, we get into the science of it, we're going to learn more and more. I don't know if you've gotten too much into that. But the one thing that we talk about a lot because I start meeting scientists, like we have discussed before when you have when doctors say there's no science and then you're meeting the bench researchers that are out there. There's gonna be a field like you're an orthopedic spine surgeon you're a subspecialty of a subspecialty. I'm a gastroenterologist I'm a subspecialty of a sub specialty. I guess yours is sub sub sub because you did spine after orthopedic. Your your next level, even though you didn't go to Texas Tech, we're gonna forgive you for that. Dr. Won Thank you. Ken Brown Yeah, that's, this is just for Eric because he gets so upset if we don't discuss that. But even when you're sitting there as a sub sub specialist, we've got all these people with knowledge in other fields, that then you start realizing you could be a sub sub specialist. So I've met researchers that I call Endocannabinoidologists because they understand so much on the molecular basis of the endocannabinoid system, which I think eventually we're going to get to, but I think all of it gets corrected if you eat right and live the right lifestyle. So our little disclaimers go to Atrantil.com or go to KBMdhealth.com and take a look at the CBD. So that's usually a Does that a whole lot smoother? That's not really my...Dr. Won I think you did great. Ken Brown We have to get that out of there. So, all right, getting back to you, because I this is a rare opportunity to have somebody with both your background, your your skill set. And now this this continual pursuit, this continual change. I'm very similar to you, I've realized at this stage of my life, that moving forward is what keeps me happy. Always trying to see okay, what what can we do? What can we do for the next thing? What can we do for the next level? I try to always talk about a recent news article or something and I want to bring this up. Not to put you on the spot. Dr. Won, How old are you?Dr. Won I am 48 years old.Ken Brown You don't look it 48 years old. Awesome. An article just came out out of the National Bureau of Economic Research, which takes on the myth that life begins at age 40. This is kind of interesting, according to this very large study, that they looked at over 257 different countries, different socio economic stages and all that. Fascinating that you're saying that Africa is now getting these Western diseases Dr. Won Yes. Ken Brown So it's it's, it's impervious to everybody. The whole world is having the same crisis that I think we face. We just got there a little quicker than everybody else. Dr. Won Oh, absolutely.Ken Brown What they looked at is that there is a U shaped curve for happiness. And as it turns out, it bottoms out at age 47.2. And the reason why I bring this up is that there's a lot of people and they were trying to figure out why is it genetics? Is it that the stressors are too much? Is it that disease start setting in right about then you start realizing your own mortality and all these other things. They don't know exactly why, but they were able to account for education, marital status, all these things. And they did show that although it bottoms out by 48 49, people are able to find their way out and they can usually do it through community and through purpose.Dr. Won Yes.Ken Brown So both you and I are beyond that now. So now we're in the happiness zone. And I think that you've done exactly that you got through a little curveball and you're like, I'm just gonna keep moving. and I'm going to do this through community and purpose. And what it sounds like, is that the first thing you did is say, I'm going to give free lectures. Tell me about that.Dr. Won Yeah, so we've been hosting a free seminar, teaching people how to prevent and reverse their chronic disease, and through whole food plant based nutrition. And there's a it's not just in nutrition itself, but it's a whole lifestyle. And that's why we don't like to call it you know, plant based diet is a plant based nutrition and lifestyle. And what I realized was I started going into plant base once I lost a few of my colleagues to cancer, they're physicians, and I myself, always thought, Hey, you know, there's a chance that I might die from cancer and the reason for that is because I've done a tremendous amount of a minimally invasive surgery and use two interpretive X ray machines and, and got significant amount of radiation exposure.Ken Brown Just explain real quick, minimally invasive and why you would have to be using an X ray machineDr. Won So a traditional spine surgery, you would make a big incision, right and then open up the spine, take away the, you know, the fat, the fascia and the muscle and then strip all of them off and gain access to the spine. And the whole concept of minimally invasive surgeries, not disrupting the soft tissue, you would make a very small incision, and then utilizing the X ray machine at the time. Now these days, you can use imaging guidance with minimal amount of radiation. But when we were first starting out 15 years ago, it was the typical X ray machine. We were protected with Lead But still, we got a lot of exposure to radiation. So I used to joke around saying I'll probably die of cancer someday. But what I realized was that I don't want to die of cancer Who does? So I started doing just a lot of research how to prevent cancer. And I just, you know, went through about thousand different papers, scientific papers, I realized we all have cancer cells, every single one of us have cancer, so we have cancer. So when we're diagnosed with cancer is a clinically significant cancer that we which we can prevent In many times and reverse, even the study from the MD Anderson state state study showed that number one cause of a cancer was diet. Number two was the tobacco. Number three is obesity, which leads back to the diet, right? And then the genetics makes up the smallest percentage, you know, no more than five to 10%. So we actually have to controlKen Brown Use your analogy one more time with a gun. I like that.Dr. Won Yeah, it is the gene or genetic loads the gun, and then the diet and lifestyle pulls the trigger. And so in that we now with better understanding of epigenetics, that the the genes are like the light switches, depending on our nutrition and lifestyle, we actually have the ability to turn them on and turn them off. So So through that approach, I discovered whole food plant based nutrition, which has worked wonders for me, instantaneously, within six weeks, I lost about you know, 25 pounds, and after age 40. They said if you do exactly the same activities level eat same thing. You're going to gain about a pound or 2 every single year, if you know then within 10 years, that's additional 20 pounds. And so starting 40...Ken Brown I'm sorry to interrupt. I just want to clarify this one thing you chose to go plant based Whole Foods based on the thousands of articles that you researched. Dr. Won Yes. Ken Brown So you were not like watching Netflix and stuff. I'm going to I'm going to follow this what the health diet or I'm going to do the game changers This is based you are not influenced you did it all on your own correct?Dr. Won Yeah. So I actually did it before all those documentaries came out. And the researchers were there. And and what happened was one of my friends from medical school, he came to visit me at one time and then he gave me a book called China Study. And I thought, maybe because he knew that I was also into business. This was about economics book. I didn't even see the cover. And then I kind of put it in the bookshelf and I forgot about it for a long time. And then once I started doing the research, there's a The China Study kept on coming up. And I said, Wait a minute, I think I have a book called China Study. Written by Dr. Campbell from Cornell, and now pulled it out, read it cover to cover, along with other studies, and then realize you can actually reverse the disease. And this has been the studies been going on, you know, there's been studies since 1950s. And so I was convinced I said, You know what, I'm going to do this for myself. And without even trying at first thing I did was wait is, you know, important, but not the most important thing, but I instantaneously lost 25 pounds. And I was back at the weight when I was in high school. And you haven't seen many you know, you don't most people think there's not too many, you know, overweight or obese Asians? Well, in America, there are plenty not and maybe not in Asia, and I was becoming one of them. And so instantaneously, I was back into my high school weight. And then I started exercising on regular basis, and I felt so much better and now I'm I feel better and stronger than when I was in high school. And until about, you know, three years ago, I couldn't even do a single pull up. And and now I can do quite a bit and my goal is by the time I'm 50 I'm going to be able to do muscle up.Ken Brown Oh, yeah, yeah, for sure. Well, I got to actually Eric super into CrossFit. So he can teach you the whole technique on that. Dr. Won That'll be great. Ken Brown We can sit there and do that. It was on last week's show of the week before we actually discussed the fact that when coke really started penetrating China, that's really when their obesity problems started the high fructose corn syrup and all that Dr. Won Oh, yeah. Yeah, all the the processed food, right. And then, you know, along with the, you know, meat consumption, and as a developed countries are getting wealthier and wealthier they're eating just like American Standard American Diet, right, all the processed food, all the sugar, all the the, you know, high fat animal products. Even in America, average Americans consume about 250 pounds of animal products every single year, which is a tremendous amount, right? And so, and then the China's Study...Ken Brown How many pounds? Dr. Won 250 pounds. I thought that's a that's a lot right? That's average Americans since I'm I don't eat any somebody is eating 500 pounds of meat every single year right?Ken Brown I'm gonna look at that cow and go. I'm gonna eat half of you this year. The whole cow.Dr. Won That is a tremendous amount. I think they said also during the Superbowl, I don't know how they come up with the numbers. Every every year during the Superbowl people consume about 1.6 billion chicken wings. Oh my god.Ken Brown 1.6 billion chicken wings. Yes. For the for the Super Bowl. Dr. Won Super Bowl. Ken Brown All right. Yeah, that is a lot of wingless chickens running around.Dr. Won Yeah, absolutely. And, and you know that the chicken these days doesn't look anything like the chickens from let's say even hundred years ago, because they're genetically modified, you know, and they have so much more antibiotics. They have so much more chemicals, growth hormones, and so people are so concerned about eating food that's not Genetically modified but most people in America don't know where the food comes from. And they don't really think about it especially when it's in a hamburger or chicken sandwich which they really do need to pay attention whether you're plant based or not, you should really know where your food comes from.Ken Brown You know, I mean I love having you on here because even as gastroenterologist and even though I think like kind of we want to treat the whole body I've I have not spent that much time really going over the whole diet thing because I naively am like okay, this is the weight I want to be. This is kind of what I want to look like when I'm when I'm at the beach is you know, if I start not seeing the the ABS or we go from that six pack to the four pack to the two pack to the no pack. Then I just start working out more. Yeah. And I got a little rude wake up call. Last week I went to I have a functional medicine practitioner. His name's Kevin Wilson. It's smart wellness now. And you know, they they do real Like deep dive into the blood work so it isn't just HDL LDL, it's you know, it's LDL, C it's Apolipoprotein B, it's all this. And my cholesterol went up. I'm feeling better than I ever felt what? And he's like, yeah, you're doing something wrong, buddy. Yeah, and you know, and quite honestly, I'm pretty much paleo so i don't i don't really do dairy or gluten, but I will mowdown some meat. Got to eat my 500 lbs. So you got me rethinking. So he's given me three months to try and reverse this. So I'm starting a little bit slow and so I'm not I'm gonna start watching your videos for sure. Because I did the thing that most people do. I went and watch Game Changers on Netflix and and which is a very fascinating documentary in the sense that that got more traction than what the health and knives over forks and all those other vegan propaganda ones, because I think that they were talking about performance. Dr. Won Yes, Ken Brown What you're describing is exactly that you're you this is not an ethical thing. This is not a a conscious choice. You were like, No, I did my research this, I can be healthier.Dr. Won Yes. I mean, I did this because for my health, and you know, I always tell people that I want to live until 120 years old, I may have had a better chance if I actually started when I was in my 20s.Ken Brown You know, that will just be you. And Dave Aspy having tea together because he says the exact same thing on his podcast.Dr. Won I think he says he wants to live forever. And so I don't know if that's possible yet. But they said he, if you do it, right, the kids who are born today have a potential to live until 150 years oldKen Brown A hundred and 50 years old, have the potential?Dr. Won Have the potential. But but the sad thing is the kids you know, between age 10 to 12 years old, what percentage of the kids actually have early signs of atherosclerosis? 75% Ken Brown What? Dr. Won 75% of the kids between age 10 to 12 years old, have already fatty strix. Ken Brown No! Dr. Won They all found that the... Ken Brown That's nuts there's no way! Dr. Won Even the fetuses are now showing up. unfortunate event because, you know, whatever, you know, may have happened. But when they do an autopsy on fetus, even the fetus, some of the fetus actually have, you know, some fatty Strix, depending on Mother's, you know, a vascular system. Right? So, you're starting at life already having early signs of cardiovascular disease, what is that? Right? And so when mom said, you know, I'm really, you know, sensitive to listen moms who are pregnant, and then also parents, they have such a difficult, you know, challenges, you know, feeding their kids, but they're not really thinking about what they're serving them, right. And I cringe when I go to a breakfast, and then you know, next table, you know, parents are serving their kids bacon, or hotdogs, and the kids and the food that is known by World Health Organization as a group one carcinogen, right. So I think we need to really step back and educate the public and help them see what they're putting on their, on their table. And when I saw the article where the kids, you know, between 10 and 12 years old, 75% of them had already have signs of, you know, cardiovascular disease. I mean, that's terrible. We're not doing something right. And we spend so much money on managing the disease, which we don't do very well. But and, you know, completely forgetting about preventative medicine because there's no money in preventive medicine. Right? That's that was our mission is to actually go to community and and teach them how to eat properly. And so, so we've done not only lectures at our clinic, but also if anybody wants to hear us talk. We'll go and give a talk. And we've gone down to the south side and then the African American churches to church in Richardson at Methodist, you know, pretty much 99% Caucasian, you know, congregation. Or you know, community centers who wants to learn about...Ken Brown You still have the guts to go to a nice Korean BBQ establishment and give a talk? I like Korean bbq man!Dr. Won Yeah, you know, for whatever reason Koreans were known for Korean barbecue, but in Korea actually. Their health is declining like in China because the meat consumption has increased processed food, and then their lifestyle is changing. But you know, they used to be one of the healthiest country in the world, because they were too poor to actually eat meat. It wasn't available. Everyone wants to eat. So if you look at all the countries, all the cities and along the Blue Zones, the the cities that have the most amount of centenarians, most people are poor. So by being rich, yeah, you may have money to spend it, but you're actually ruining your health. Ken Brown Alright. So I was going to ask you this, and it's a perfect it's a perfect segue right now. So I was talking to one of my patients today that she's going to be a guest here shortly what happens to have Crohn's disease and gives back to the community just like you she works as a counselor and does all this and she happens to be a speech therapist for underprivileged kids with autism. So part of this, you know, they, they send them with the with the school system. And so her and I started talking, I started talking about how last week we did a whole show on a chemical that makes plastic flexible, called DEHP you've been exposed to it a ton as a doctor. So have I that's what IV bags are. That's what the tubing is, all the catheters and tools that we use to be flexible so that we're not puncturing where we don't want to use this chemical dehp. And when you said in utero, they're finding stuff as it turns out in utero, if a if a woman is exposed to it, it just goes to the fetus and causes all kinds of stuff. Dr. Won Oh, wow. Ken Brown So what her and I talked about is I'm like man, well, what can what can you do to circumvent this autism at you know, I mean, basically epidemic She's like they're too poor to eat healthy. Dr. Won Yeah. Ken Brown So now you just said that when countries were poor, they ate healthier. So let's talk about the cost of, of living your lifestyle. Is it possible if I don't have a high income to eat a plant based whole food diet?Dr. Won Absolutely. When people are thinking Whole Foods plant based, I think a lot of people get that confused and they think it's vegan. And then and they get meat replacement products, which are actually quite expensive. Right?Dr. Won So when you do... Ken Brown This guy did that when he watched game changers and it didn't work out well. Dr. Won Yeah. Ken Brown Because I think the either the fillers or the soy or something may be very inflamed. Dr. Won Yeah. Ken Brown So I backed off.Dr. Won So one of the things I really you know, it's also talked to the vegan community is that you know, they've already given up the meat which is the one of the most difficult thing for a lot of people. However, they also need to get away from the processed food because most of the the meat replacement products are processed. So when you're eating a whole food plant based, you are eating non processed or minimally processed food. And so the best place you know, and the best pharmacy is actually with F, you know, FARMACY right Farmacy is in the produce section, that is the medicine, that's where people need to go shop. And so if you get dried beans, it costs pennies, right? Versus, you know, getting ground beef or getting chicken breast. So actually eating whole food plant based can be very, very inexpensive. That's why and along the the Blue Zones, the you know, like nicoya, Costa Rica, Okinawa, Japan, you know, Sardinia, and aquaria. All those countries, all those communities, people were relatively poor, they're not wealthy at all, even especially like nicoya they were eating mostly beans Ken Brown Where's the Nicoya? Dr. Won Costa Rica. Ken Brown Okay. Dr. Won Yeah. And it's one of the cities and Blue Zones that has the most amount of centenarians, right? And and there were most they're all 98% eating plants because they were too poor to eat meat. And they're living beyond and then they didn't necessarily go to the gym, you know, or CrossFit or 24 Hour Fitness, because they walked every day everywhere, they didn't have cars, right? So they're moving their body every single day. They're eating mostly plant, and because that's all they had available to them. And then they had sense of community and, and they had sense of purpose. And you mentioned purpose earlier, I think that is so critical. You have to have a reason for living, right? You have to have why, as long as you have why, and sense of purpose, no matter what challenges are in front of you, you can overcome them. And that's how powerful human beings are. And if you decide to just give up, that is a failure. And no matter how many mistakes you make, how many, you know, failures and debt that you face, as long as you stand back up, and then continue to, you know, pursue your purpose and your why I think Most people will be very, very happy.Ken Brown Yeah, I think that you saying that you came at 11 years old, you started your journey, probably not the easiest time in your life.Dr. Won Not at all, I didn't know how to speak English. And but all our family, you know, including my parents, we worked as a janitors, you know, don't want to get my parents in trouble. But when we're 12,13,14 years old, we used to go help our parents, you know, clean the toilets in the building and then I still pass by one of the buildings we used to clean when I was 14 years old. And and that's what we did as a family. And then they, you know, open to the flea market store. My mother was shot at, you know, twice when she was working at the flea market store when she was being robbed. Right. And luckily, they missed, thank goodness and then where my parents lived after I left for college. There was a drive by shooting at my parents house. They got the wrong House, it was supposed to be the next door. But my parents were asleep. And then fortunately, their windows were shattered. And so, you know, we grew up very humble. And a lot of people think that, you know, you're a doctor, you must have come from a doctor family. That wasn't the case at all. And we live in the government assisted housing. But, you know, our parents always gave us you know, good foundation, and always, you know, taught us to have purpose in life. And that really, you know, sunk in with us for you know, since we were little child Yeah, and, and in always the life force, you know, living the life with purpose, and, and that was our mission.Ken Brown So, you come over here you go through this kind of hardship. Now, we kind of tongue in cheek, talked about how I hope you're as smart as Eric obviously Eric's a very smart guy. He's my crna and he's he could he's still continues to do whatever he wants to do he has entrepreneurial spirit very, very like minded like us. He's very big into purpose into raising his kids the right way and all that stuff. But your your academic background is super impressive. I mean, you know, just for the average person that says, Oh, that's a doctor. Now there's levels of doctor, there's levels of med schools, you gotta really work to get into some of these places. And I, I'm just so impressed that you basically have to put your career that you were worked so hard to do, and you went awesome. I'm gonna work on this now. I love that. I think that is the coolest thing. And I'm learning for you. So I want to ask you a couple quick questions. Dr. Won Yes.Ken Brown Because these are the arguments that I get. So the community that I'm in I'm in fact, I should. We'll we'll talk afterwards, but I've been part of some really cool entrepreneurial groups, where it's just like minded people that all they do is sit around and say don't step on this land mine. I blew off my left, you know, theoretically, in a business sense, I blew up my left foot doing that I wouldn't do that, try this software instead try this thing and you know, you read books and stuff like that. Well, a lot of these people are the Paleo community, and they're really smart people, Chris kresser, Rob Wolf, you know, become friends with them in these groups. And what what I'm hearing is, is that in Kevin Wilson, my doctor is not plant based. He's very big into paleo and all these other things. So a couple curveballs towards you. Dr. Won Sure. Ken Brown All right. Let's talk about the thing that I get asked a whole lot. Lectins. So you said Dr. Beans do this, what's your thought on lectins? Do they create and then that's going to lead us into the microbiome and and eventually into your entrepreneurial spirit where you continue to grow? So that's where I want to head with this. But can we talk about lectins real quick?Dr. Won Yeah, absolutely. I think that's a you know, very interesting topic. And so if you think about the Lectin especially in the beans, no one can eat them being raw. You don't eat dry beans, you can eat it, you can't digest it, and we don't recommend it. Right? Because if you eat it, you're going to get nauseated, you're probably gonna throw up. However, if you cook them properly, right, all the lectins are gone, right? And so lectins are there so that the plants can protect itself and so a little bit it's actually healthy for you because you're stressing your body. However once you cook them... Ken Brown Hormesis.Dr. Won Yes, absolutely right.Ken Brown The term Hormesis means that you stress your body a little bit so it adapts.Dr. Won YesKen Brown That's why we exercise that's why we fast that's why we do things.Dr. Won That's why you know, we get exposed to heat that's why we take cold showers right? Ken Brown I don't take cold showers. I refuse to go that route. I'll sit in a sauna but I will not do a cold shower.Dr. Won You should try it you know maybe 10 seconds first and you know 15 seconds in the beginning you hate it. But you'll learn to love it. But the lectins...Dr. Won We're gonna get to elections really quick. Just Just this reminds me my late father in law passed away a few years ago, we were watching a show on navy seals. And a Navy SEAL actually did a obstacle course, where he first soaked himself in warm water, and then did the course. And then they put him in ice water. And then within a sofigel probe, they show that he dropped his core temperature and then through various Navy SEAL techniques, he raised his core temperature. And so my father in law, this is on Christmas, this is about 10 years ago, goes you know, it's Dallas, it's not that cold, but it's cold enough. It's It was like 30 or 40 or something. He goes, I bet you can't even get in that pool. I went out there with my son and my father in law and I jumped in and like a total weenie jumped out in about 10 seconds. So the whole cold thing I think that's funny, but all right, that's the whole point is is that lectins can do this. Let's get back to lectinsDr. Won Yeah, so but once you actually properly cooked the meals, yeah, I recommend soaking them at least for eight hours or even 24 hours.Ken Brown Soaking the beans first?Dr. Won Yes, soak the beans minimum of eight hours. If you have a pressure cooker you don't need to soak them you just dump it in there and you cook itKen Brown Do can beans qualify?Dr. Won The can beans are already cooked so you don't even need to cook it you can just open it and start eating them.Ken Brown Do you find can beings unhealthy or do you always do whole food? Dr. Won At the house we have both dry beans and canned beans because to make it a little bit more convenient, right. And the can beans are, the studies have shown that they still retain just as much nutrients. And so when I'm really busy, I would open up a can can beans with the my whole grains and mix them up along with different kinds of spices and then along with different greens, but once you cook the bean most of the lectins are gone. So there's really nothing to worry about. And so you don't need to take Lectin you know, supplements or anything like that. If you properly cook the food, then there's really no issues with lectin and if you think about it, so beans are the most known for lectins right? Every single one of the cities, right? There's one common theme among Blue Zones, five cities that has the most amount of centenarians, right? The research by Dan Buettner from National Geographics every single one of them that the common theme was Beans, beans, beans, beans Ken Brown Shut up! Really? Dr. Won Every single one of them there was their main source of protein was their beans.Ken Brown Dang. And I've actually been avoiding them because I'm trying to you know, I've just kind of go with the no grain thing.Dr. Won Yeah, so the beans is one of the healthiest thing one can consume. Not only it's a great source of protein, but also it's also has so many fodder nutrients. And I consider them as a superfood really, really cheap. Super food, Ken Brown What are your favorite beans? Dr. Won All of them, but we have at the house about 10 different kinds of beans. And then when I make grains I usually mix like black beans, pinto beans, white beans, navy beans, kidney beans, along with let's say buckwheat brown rice, wild black rice, barley, mix them up, and then that's how I make the rice and so rice and beans. I don't you know we definitely avoid any refined grains such as white rice,Ken Brown Oh you do? Dr. Won Yeah, I we avoid any kind of white anything that's white right?Ken Brown Okay, so I hope that helped my wife is listening my wife's Puerto Rican. Dr. Won Uh huh. Ken Brown So i mean...beans and rice. Yeah, it's just pretty much it's whatever. I'm like, Honey, what are we having? She's like salmon, and beans and rice.Dr. Won Yeah. That's good. And you just got to put in some greens.Ken Brown But but but but you avoid the white rice Dr. Won White rice. Yeah. So the...Ken Brown As a Korean you still avoid white rice because we love I mean, that's actually our favorite. If we're going to globalize our cuisine for my family, I got a 15 year old a 13 year old and we essentially eat Japanese in this order. Japanese, Thai, Vietnamese, Chinese almost anytime we get a chance to eat out.Dr. Won You're inner asian. Ken Brown I'm we are definitely Yeah, it's a it is it is definitely our favorite cuisine. So we end up eating a lot of rice. Dr. Won Yeah. So interesting fact is that the, the in Asia, you know, while back the white rice was you know, it's extra process right? So this was actually for aristocrats or the wealthy individuals, all the poor people ate brown rice, which is less processed it's unprocessed. Right? And so the the poor people actually live longer they were healthier than rich people, right? Same thing happened 100 years ago, the rich people ate white bread, right? And then the the poor people ate the whole grain bread. And guess what it was a poor people who are healthier, right? So you know, grains, especially white grains, they're extra processed. And so and also raises your blood sugar level much, much faster and raise you know, increases more insulin production or release of insulin. So we try to avoid anything that's processed. So including the the grains. So if you eat you know, brown rice or you know buckwheat barley, black white rice those are the grains that I would recommend that I say it's whole grains not grains, whole grains, Dr. Won Whole grains?Dr. Won whole grain.Ken Brown Beans, beans, okay lectins get destroyed when they get soaked and then followed by cooking and or canned. Dr. Won Yes. Ken Brown And then...Dr. Won Because canned beans are cooked. Ken Brown Can can beans are cooked and as far as the grains, so yeah, the This works really well for you. And I know right now that there's, you know what I've seen with diets, especially when people make a living like if they have a book or so I mean, I hung out with Rob wolf, the guy looks amazing. He's been keto for 10 years. And Chris kresser is essentially you know, straight up paleo and, you know, I know his blood work is amazing. We've talked about that. And so there are, you know, the the things that actually work it's not working for me. My doctor just told me that's why I'm like, Oh, yeah, we need to we need to call Doug, I need to I need I need to eat his brain and figure out what's going on here because maybe my genetics, so you use the term epigenetics a little while ago. Explain what epigenetics actually is, because there's some confusion around this.Dr. Won Yeah. So just to simply put it way I like to explain it is our gene is like a light switch. Right? So we are born with certain genes, unfortunately, for some people, and they may have a greater risk of developing certain type of disease. But just because you carry the gene does not actually mean you're actually going to develop those disease. But there's a lot of external factors, environmental factors, including the cancers, right. And so by a proper nutrition and lifestyle, you actually have the ability to turn the genes on or turn them off. So what that tells us is that you actually have a full control. So you know, like Elizabeth Blackburn who won a Nobel prize from UT Southwestern for discovering telomeres did a study with the Ken Brown She's the one that discovered telomere races?Dr. Won Yeah. So along with the telomeres, and that's what she, she won the Nobel Prize,Ken Brown Did not know that wow, out of here, out of here in DallasDr. Won Yeah at UT Southwestern. Ken Brown That's, that's impressive.Dr. Won So she did the research with Dean Ornish, and they got group of patients who had early stage prostate cancer. And then when they did the genetic study, all the over 500 cancer genes were actually turned on. And then they spent three months changing their diet and lifestyle. And then they did the the genetic study again, all the genes were actually cancer genes were turned off over 550 cancer genes, Uncle genes are turned off. So you only took them three months o so especially prostate cancer, right? Especially if you catch them early stage, you really want to treat them with diet and lifestyle change. They said the the traditional surgery, whether it's a chemo or the surgery does not prolong only one out of 49 people actually live longer after getting traditional, conventional medical treatment.Ken Brown Well, when you start looking at some of this, I listened to a podcast called medical reversals. It was on Freakonomics, the Freakonomics podcast. And they they actually had some doctors on there. And they and if you look back at all these medical reversals, so basically your doctor says, do this, and then we go, Oh, no, that was wrong, because now we've looked at our cohorts of 10,000 patients over 10 years. We can go on and on about that the estrogen replacement therapy, one of the things that's been brought up and I brought this up to my doctor because my cholesterol is statins and statins have not been shown to improve lifespan. And so the question is, do they actually decrease the incidence of events, but it has not been shown to improve lifespan. So now I start. I'm at that stage in my career in medicine where I'm starting to question so many things. I'm having patients come to me, and well, let's throw this one out with autoimmune disease. And you and I were talking about this I treat a lot of Crohn's disease, ulcerative colitis. I use drugs like Remicade and humera. Have you had any experience with as an orthopedist you're going to be exposed to rheumatoid arthritis, you're going to be exposed to ankylosing spondylitis. Poly arthropathy from these other things. Have you had any wins with using your method?Dr. Won Absolutely. So some of them are my patients and some of them are attendees to our free seminars. And I gave an example of Denise she gave us a permission to talk about her. And so she came to us suffering from severe rheumatoid arthritis and she's been on multiple medications, even methylstrexate as in the past and humira. And humira costs 25 to $50,000 a year. Right? And one of the side effects is heart failure. And she began to have a severe heart issue. So they had to take her off. And and she she was in severe pain. And so I said, you know, you got nothing to lose. You tried everything else. So why don't you try a whole food plant based nutrition, and that's what she did. She did that. January 1, 2018. Within two months, she was in remission. All the pains were goneKen Brown On her alright rheumatoid arthritis? Dr. Won Rheumatoid arthritis. Ken Brown So rheumatoid arthritis is an autoimmune disease. Autoimmune means you something turns a genetic switch on and your body starts attacking yourself. In gastroenterology, I see it with all sort of colitis, Crohn's disease, celiac disease, autoimmune hepatitis. In your field. You see it with the joints.Dr. Won With the joints rheumatoid arthritis, but we also I've seen patients with multiple sclerosis, right? And actually, this was another patient who walked in or not walked in, came into the clinic on a wheelchair and had multiple sclerosis. So we actually... Ken Brown In a wheelchair?Dr. Won In a wheelchair.Ken Brown That's very advanced MSDr. Won It's pretty advanced. And and the patient went whole food plant based, and was six to eight months later, when they came back for a follow up visit. He actually walked out walked in with a cane. So he still had weakness, but it got him off the wheelchair and now he's able to strong enough to actually walk with a cane. Ken Brown Just diet change? Dr. Won Just a diet change. And he was off to all the medications and he's not the only one and there's a one lifestyle medicine physician even up in New Jersey, a good friend. She was initially infectious disease doctor and during her residency or fellowship, she woke up one day completely paralyzed. Ken Brown What? Dr. Won And that's how she discovered she had multiple sclerosis. And to a point she was walking with a cane and she was bad to get on a wheelchair. And she made the she discovered she read an article about blueberries, right? She said No way. There's no way and this can't be and she starts researching and really realized the autoimmune disease starts from the gut. And she needed to find a way to decrease inflammation. And she needed to once she healed her gut, and she changed her complete, you know, nutrition when whole food plant based. 10 years later, she ran a marathon.Ken Brown I'm sorry, I don't have any Kleenex. Do you have any Kleenex because I have tears of joy. I just had an orthopedic surgeon say that. Everything starts in the gut. Oh,Dr. Won Yeah. We think that you know, a lot of the the lifestyle medicine physicians and believe that autoimmune disease may be in a different sort of autoimmune disease, whether it's rheumatoid arthritis, Hashimoto thyroiditis, multiple sclerosis, maybe it disease, it all starts from the gut. And then it manifests to a different disease based on our genetic makeup. And so our treatment method whether it's, you know, lupus, multiple sclerosis, you know, Hashimoto thyroiditis, it's all pretty similar. You know, they may, we may make little bit of a different protocol for them, but overall as a whole food plant based, and many of them improve significantly.Ken Brown Wow, that is. So we've actually, that's actually a common theme that we talked about, we have brought some people in, but my thing is we've got lots of data to show that when you have an inflammation in your gut, that leads to an inflammatory cascade that can cause this epigenetic phenomenon. And so somebody sitting around listening, so I want to talk about what else you have going on, which means that you've taken it to the next level, but I everything about, about this show and about what we want to do is talk science first. Clearly, you're a brilliant And you know, you're, I'm a, I'm a gut doctor. So you know your s-h-i-t. So I wanted to throw this article out at you because it's fascinating that we can talk disease. And I could sit there and say if you've got rheumatoid arthritis if you got ms if you have anything, but there's also one underlying thing that happens to all of us and you keep talking about the Blue Zones. A recent review article, my little secret weapon will eventually be able to disclose who it is, but she sent me an article yesterday. And with you coming on it is a review article on the new insights for cellular and molecular mechanism of aging and aging related diseases. herbal medicine is a potential therapeutic approach. So in other words, what this title says is, yo we're all aging. And why do you want to load the gun faster than it should be loaded? So what this article looked at is they go into the background A little bit where 900 million people in the world are over the age of 60. Dr. Won Wow. Ken Brown And you just pointed out that it doesn't matter where you live now it looks like it's it's pretty much spreading everywhere. So aging, which can be divided into both pathologic and physiologic. So if you are perfectly healthy, you're going to physiologically age if you choose to load your gun faster, that's pathologic aging. And this article gets into really cool geeky science about the complex biological processes and the decline of tissue and origins and structural degeneration and then they go into telomeres and then they go into the fat, a common thing keeps popping up. And it is reactive oxygen species or oxidative stress. Dr. Won Yes. Ken Brown So stress at a cellular level, or inflammation at a subtle level leads to aging. Dr. Won Yes. Ken Brown So if you didn't care about anything about the fetus having a heart attack or a 10 year old having coronary artery disease, We spend a lot of money trying to look younger. I just got done talking about the other article that said that at age 47, maybe that's when men look in the mirror and go, Oh, I'm I'm there. I don't know. It all comes down to reactive oxygen species. This leads to they can actually get into the actual mechanism. So one of the things I run into that we have discussed, which is I'm sure you've run into because I think your field is a little bit less holistic than gi, which is probably because the gut affects so many things. But I imagine if you're trying to talk to one of your colleagues at a conference and say hey, plant based they probably look at you like what?Dr. Won Yeah, I'm I don't represent typical look of orthopedic surgeon right? So if you imagine orthopedic surgeon those of you who don't know like in medical school, we are like the cords pedic surgeon smart jocks, right? Everyone's hitting the gym, you know, bone broke me fix. Big guys, ex-thletes, right? And then somehow I snuck in as a nerd, right?Ken Brown So I have I have a friend who played football for the San Francisco 49 years played at the University of Notre Dame. And we have or he's very good friends with orthopedic surgeon named Brian rhadigan. And he played linebacker for Notre Dame, and if there is ever the avatar of what I thought this guy was just jacked, and you know, and he's an orthopedic surgeon now for Notre Dame. Dr. Won Wow. Ken Brown But anyways, yeah, so yeah, you you are talking different than the typical orthopedic surgeon.Dr. Won Yeah. And so but yeah, but I think even with orthopedics, and also especially in spine, some of our patients, after if they choose to follow our diet and lifestyle modification, they came back even with herniated disc, most of the inflammation was gone, pain was gone, and so they they would cancel the surgery. I said Congratulations, right. And so if I can help patients, that surgery is definitely the last resort.Ken Brown Say that one more time you got paid to operate and you were happy when you didn't have to operate?Dr. Won Yeah, absolutely. Because there's plenty of patients who's not following the lifestyle modification and who is in agony, who failed all the conservative treatment, who's going to need the surgery. But you know, what I would love to be able to do is to prove to the medical community that so many of the surgeries and procedures that we do are completely unnecessary, because if people are willing to make the lifestyle modification, if the physicians actually know and teach their patients, how to make the modification, because most of them do not know. Right, then I think, you know, many people can avoid significant surgical procedures, whether it's a cardiac cath open, you know, open heart surgeries, which we know that does not extend anybody's life, right. And same thing with spine surgery. And, you know, orthopedics is a little bit If you break a bone, you broke a bone and you need surgery to fix it right? Ken Brown Don't try to hobble into whole foods after that skiing accident.Dr. Won I don't think that whole foods is going to fix that broken bone, but it may help you heal faster, but you're probably going to still need surgery. And so that is one of my mission and I get a great enjoyment out of it. And you know, I remember one patient who walked in who had a thoracic herniated disc. And you know, in order to do the surgery, we have to do a thoracotomy. So basically cracking our chest open the compress the lung in order to get to the spine from the front. And I said, you really don't want to have this surgery. We can do it if you want to. However, why don't you give me three months make this changes come back in three months. If it doesn't work, then we'll go ahead and do the surgery. She came back to clinic and three months along with her husband, she lost 40 pounds. He lost 60 pounds, right? And she said her pain was gone. And she said doctor, I don't need your service. anymore awesome congratulations. So I think it is very possible and you know once once you have seen that I just get a kick out of itKen Brown I'm feeling like a little jerk right now because we did a show on using cell phones while there people around the bathroom doing social media posts and I I told everybody to keep doing that because it creates hemorrhoids so they can come see me. I feel like a jerk. I'm over there encouraging, sit on the toilet longer and make an appointment with me.Dr. Won That's funny.Ken Brown Oh, you're making me look bad man. I want to talk about something about this article because I we use the term reactive oxygen species all the time. Now one of the things that they got deep into this article is about a lot of the end origin disease that kills most of us. cardiac disease strokes. dementia. A lot of it comes down to blood vessels. Yes, the endotheliam meaning that as our blood vessels, all this inflammation leads to endothelial dysfunction, and impaired activity and arterial stiffness. And the reason why I bring this up is because I'll plug this the polyphenols and Atrantil we do know that they actually improve the most polyphenols when taken in. There's literature for this. But when we first launched Atrantil we did it strictly for people that bloated and then we had all these people that kept staying on it. And that's when I started backing up because I was looking at one little problem then went, Oh, this is actually it's sad that it's that I'm now learning because all I've been doing is doing plant based, but I started with a pill and now I'm working my way to lifestyle. Yeah, which you're doing lifestyle. And you realized, Hey, I can help people in different ways. So you noticed immediately that endothelium is really important. And when we talked before and you brought me some gifts, I would like to talk about what else you have going on here because very clearly, you have put some serious thought into this. And then I came backwards. I started with a plant based product to treat something and now I'm learning about a plant based lifestyle. Yeah, you did the opposite. You started plant based lifestyle and said, I'm going to produce the best product for that. Yeah. So tell me what you got here.Dr. Won Yeah, so one of the things that we developed was, is called Neo Nox is a nitric oxide booster,Ken Brown Neo NoxDr. Won neo neo, no x, no x, and this product was developed without intention of developing a supplement company. what we realized was as I was doing research, even as a physician, we knew that heart disease was a number one killer, but I didn't realize how severe it was. It is actually the number one killer of both men and women worldwide. Right? And, you know,Ken Brown Yeah we start seeing once women go into menopause. Yeah, they get the same risk as men.Dr. Won Yeah, exactly. And, and so and a lot of women just getting neglected and they think it's a man's disease. And but women develop a cardiovascular disease just as much as the guys and, and one in three deaths in us is related to vascular disease. So pretty significant amount. And it all comes down to endotheliam and nitric oxide, what I realized was the most important molecule in our body because it saves endotheliam, and is produced it within our endotheliam. However, as we age, by the time you're 40, you lose about 50% of your ability to produce it. By the time you're 60 you lose about 85% of your ability to produce nitric oxideKen Brown Say that one more time.Dr. Won So by the time you're 40, you lose about 50% of your ability to produce nitric oxide, which is the most important molecule in our body.Ken Brown Why do why do we do that? Dr. Won So a few things number one is produced in your endotheliam. Right intercellular is basically the inner lining of your artery. And so, as we age, we develop atherosclerosis, we damage the endotheliam. So therefore, we lose the ability to produce the, the nitric oxide, but along with that... Ken Brown So the inflammatory process damaging the endotheliam does not allow us to produce the one molecule to repair the endotheliam.Dr. Won Exactly. And so and not only the nitric oxide, is that the strongest vasodilator that lowers of blood pressure, and then also vasodilate the vessels so they're more nutrients and oxygen can be delivered to the end organs, right. It also stimulates the stem cells and activates the stem cells and mobilizes the stem cells, Ken Brown nitric oxide does? Dr. Won Nitric oxide, and that's how we really actually got into the nitric oxide because we knew we needed to boost the nitric oxide to our patient when we're doing orthopedic stem cell therapy, right to to help them prevent either You know rotator cuff tendonitis and tear surgeries Ken Brown We had we had weighed with 10 on our show the orthopedist. Dr. Won Yeah. Ken Brown From Fort Worth that had the the Panama stem cell clinic.Dr. Won Yes. Yeah. Ken Brown We deep dived into stem cells. That's some cool stuff. Yeah.Dr. Won And but, but most people are looking for that magic pill. They want the injections, right? And the stem cell therapy, but you need to activate them and people who needed the most are typically 60 Plus, right, sometimes 40 Plus, but most of the patients we have arthritis are 60 Plus, but they can't really activate their stem cells because they don't have any nitric oxide. That's part of the reason why people develop cardiovascular disease. people develop diabetes, right? people develop erectile dysfunction, which is a vascular disease. Right. And so that's, that's why the even Biograph Cialis only works on 50% of the population.Ken Brown So one of the reasons why game changers has been so much more well received is that they have a whole segment on nighttime boners Yeah. And how eating a plant based diet actually improves erectile dysfunction. Dr. Won Yes. Ken Brown And so and not just erectile dysfunction actually improves nocturnal erections I should say. Yeah, boner seems a little bit unprofessional. Dr. Won You are a doctor.Ken Brown But um, yeah. So that's, that's one of the things so it's, it's when you talk anti aging or you talk sexual performance, that's what people spend all their money. Yes. They don't sit there and go, Oh, I'm going to have a heart attack. Yeah, when really, it's all the same process. It's all the same thing. The thing that's making you look older, the thing that's making you not perform as well in bed is the exact same that's going to kill you! Dr. Won Exactly. And, and, you know, the dementia, which are mostly now we're realizing that is a vascular disease also, because you're just not getting enough blood to your brain, right. And so, and also lack of energy, you know, after age 40, everyone's fatigue suffering from fatigue, lack of energy, because mitochondrial biogenesis is actually initiated by nitric oxide also. So it helps nitric oxide stimulates the production of mitochondria, which is the energy source. Ken Brown There we go. Yeah, so that's the that's the energy source of every cell. Every cell has a little power plant. Yes, it's called the mito

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Knowing the Risks of Plastic and DEHP Can Save Your Family

Play Episode Listen Later Jan 16, 2020 75:58

Remember, I am a real doctor Eric is a real crna. We do do real medicine. But this show is not intended to diagnose or treat. Please, if you have any issues like rectal bleeding, go to our website, kbmdhealth.com. Download the E book, learn about it, but make sure that you talk to your doctor about it.Eric Rieger All right, here we are. It is gut check project, Episode Number 28. I am here with your host, Dr. Ken Brown. What's up Doctor Brown. Ken Brown What's going on Eric? Episode 28. Eric Rieger Episode 28.Ken Brown Lots of energy 2020. We're just wow. Eric Rieger We're so close to 30, it's what, six more years. seven more years. We could run for president release the show.Ken Brown It's so weird when I'm sitting there doing colonoscopy recalls. And I'm like, come back in 2030...gah! It's weird. Eric Rieger Yeah, that's good news for those. Everybody. One unique thing. everybody complains about the prep. So if you if you have to have a colonoscopy and you're not looking forward to the prep, you are not alone. Nobody likes it.Ken Brown You know what, there's a video that I have on my website, Kenneth Brown, MD. com. That's more for my my clinical practice, but I've got a video that can actually talk you through how to get through that prep and a few little bio hacks to do that. I've been through a couple preps myself. I've taken them all. So when patients are like, you have no idea I'm like, No, I do know. I do know, Eric Rieger I'm fully aware. Ken Brown Yeah, you can actually go on the website and see it or you can go to YouTube and see my bare bottom there for the world. Because I mean, the one thing that you and I do do we do... Eric Rieger You just said, doo doo. Ken Brown Okay I did, yea you're right. I am a gastroeneterologist but the one thing that we do is we live it. I mean, we We will last week I was fasting. I did a five day fast.Eric Rieger You did? And you did well.Ken Brown I did. I I liked it man, that erexin erexin is a hormone that kicks in that creates energy. I became euphoric again. I was just chatty Cathy run around loving it. Eric Rieger It's a wild thing to see play out the erexin. Having done it myself, it's it's when you're not expecting it especially.Ken Brown Yeah, totally. And this time I kind of did sort of the fasting mimicking diet where I kept the calories down. It was almost exclusively just water. But I did cheat a little bit, but not cheating. I kept my calories down. I allowed myself to choose some celery once in a while. And if you look at valter Longo's data when he talks about the fasting, mimicking diet, they allow you to have up to, you know, whatever 800 calories and you can still trick the body into fasting. What I really enjoyed was my family's getting more used to it so they weren't like I like I was a little irritable at some times and you know Loyda was cool with it. She understood. She's like, well, you're fasting. And, you know, so it was there and so the kids were kind of making fun of it. But when we sit there and look at it, and you realize that I'm trying to turn on some stem cells and all these other things, I really felt like I'm gonna make this a regular part every three months. I'm gonna try and do a five day fast. Sounds really daunting. But when you look at the data, if you get a chance, there's on amazon prime. If you're an Amazon Prime member, there's a documentary called fasting and they interview what I consider the fasting experts. They've got Jason Fung, they've got Sachin Panda. They've got Valter Longo and they all talk about the different types of fastings. And what you achieve with each oneEric Rieger Yeah, no, I totally worth it. Very low cost. It's something you can do and there are tons of benefits. We probably should do a fasting reset episode, just specific to what we can find and then we've had nurses and different technicians that we've worked with who've decided to implement fasting as part of their own healthy regimen. who already seen lower blood pressure and different things like that? So it requires really no true investment. It just requires a little bit of discipline.Ken Brown Yeah, and it's a it seems once and I remember what was the conference live it to lead it Conference. I was lecturing and I that that was the first conference where it was a fasting conference. And they purposely did not serve anythingUnknown Speaker No.Ken Brown We went all day.Eric Rieger All day. Ken Brown Everyone in that conference about 400 people. Eric Rieger But you're all in it together.Ken Brown Yeah. That that is Dr. Daniel Pompa. And he's the one that really kind of got me thinking about fasting. And he's, if you want to check him out, he's he's awesome. We know we know Angelo, his his. who's the CEO right now? Anyways, we're always doing business with these guys. They're amazing people. Dr. Dan Pompa. Check it out. I did his podcast and we and he is somebody that is extremely knowledgeable about fasting realizing that that turns on cellular health.Eric Rieger Definitely. Well, let's do a quick reset so we can get down because we have actually quite a few topics to get to today. So episode number 28. It is the gut check project. I'm Eric Rieger here with your host, Dr. Kenneth Brown. As always, still sponsored by Atrantil, Atrantil chock full of pro anthocyanin, polyphenols, polyphenols, you don't have to have gut distress to benefit from Atrantil do you Dr. Brown? Ken Brown You do not. We're learning a lot and I'm going to get into some literature today and get into some data explaining about how this is actually super important because what we're going to talk about is something that is affecting your health, and it is screwing all of us up. So if you are a human living on planet Earth... Eric Rieger Most of us. Ken Brown You need to listen to the rest of the show. I'm gonna geek out a lot this is gonna be some serious science, but it's super important because we got stuff going on in the world right now that is affecting you and I can tell you how the polyphenols actually help protect you against what I'm going to tell you about that's everywhere.Eric Rieger Go to lovemytummy.com/kbmd lovemytummy.com/kbmd to learn more and get your own AtrantilKen Brown Atrantil!Eric Rieger And then also go and visit our brand new website it KBmdhealth, KBMdhealth.com. You can get your hands on Atrantil there as well as Dr. Brown's signature package which includes Atrantil as well as CBD. So why in the world would somebody want to combine Atrantil and CBD? Ken Brown Well, that is a great question, Mr. Eric. And one of the reasons why we learned through the science was as I was developing Atrantil I started talking to a lot of different scientists and contrary to what people think there's tons of science on CBD cannabidiol tons of science on the endocannabinoid system. As it turns out the polyphenols in Atrantil, actually allow your body to produce and keep around more of your own. endogenous endocannabinoids, meaning you produce your own CBD like molecules called anandaminde and 2-ag. And I know you're going to talk about that a little bit. We'll get to that. Yeah. But basically, you can like it's, it's a exponential growth of your own endocannabinoid system. I started looking into this because when we were first treating people for their gut health, I couldn't believe how many of my patients said, you know what I'm still taking Atrantil my gut feels better, but I just feel better. Everything's better. And then I had to start looking into it. I went, Oh my gosh, the polyphenols, the post biotics the microbiome, and the endocannabinoid system is just one big Venn diagram and they all interact with each other. Eric Rieger They definitely do. Ken Brown And we're going to talk about that a little bit later also. Eric Rieger We that's something once again, you alluded to it earlier, we actually work in a clinic and do procedures. We see people all of the time that take those things combined also with a healthy diet that just simply are feeling and living better, which is great. So kBmdhealth.com. You can find the store, you just pan down the page and the brand new website, which soon will have some repository for CBD information research, we're going to talk about Oh, here soon we will have the repository on rectal bleeding. So if you've ever worried about somebody who may have seen spotting in their underwear suddenly use the bathroom and look down and they saw a little bit of blood, we're going to try to help people stave off the panic and yet find good solutions and answers for them so they can stay healthy. Ken Brown Yeah. So if you're wondering why in the world, we just did the right turn towards rectal bleeding as it turns out, that is the most search term that people get super worried about. Eric Rieger Yeah, it is. And we get the most questions about rctal bleeding. Ken Brown We get the most questions about that. So if you've ever if you have a family member, if you ever seen blood in the toilet, it's scary. And we're going to take that head on and I'm going to tell you how that you should not ignore it. Never ignore it but we put together a really cool ebook that's very informative. I think it's very entertaining, I'm very happy with with Drew Parker helping us out with the graphics on that he's a fantastic digital graphic designer, and I think it's going to help a lot of people and if I can just get a few people in to get checked out so that they don't worry. Much like we see with my colonoscopy video i get i get comments all the time, where people like thank you for doing that video. I went in and I had several large polyps. I never would have done it had it not seen that. That's the same thing. We're here to help everyone. I just want to see people get healthier. Everything that we talked about on the show is some way to augment your life. Sometimes it's gut health. Sometimes it's lighting discussions. Sometimes it's just whatever we think you and I learned something we're like, we're going to share this with the world.Eric Rieger Yep, definitely. So be sure Stay tuned. We will definitely make an announcement. If you are not a member of the KBMD community already, just go to KBMDhealth.com pan all the way to the bottom, just give us your name. It'll allow us to have your email and then you'll be looped in as soon as we have the rectal bleeding stuff that you can share with anyone, and anyone coast to coast. If they need help they could use this information, it would help them out.Ken Brown Yeah, and we're trying to grow this. We're getting some really good feedback. If you have any questions, if you want us to talk about anything, we have access to experts. That's what I ultimately want to do, if we're going to talk about so today's show, let's talk about the short term. Today's show, we're going to just kind of get caught up on a few things. And I really want to dive deep into this science about things that are hurting you that you can prevent one particular thing in the environment that I know that we can help people with. And then going forward. One of the exciting things that I want to do is I'm going to start bringing in some seriously geeky experts so that we can get to some of the science that's out there, that most people don't even understand that we have a community of PhDs surrounding us of the MD's surrounding us. And they're doing some crazy stuff, but they're not out there promoting it. They're not on Instagram or Facebook and other stuff. You gotta dig deep. You gotta bring them in. And oh my gosh, you'll learn so much. That's what we're gonna do in 2020 this thing is going to be a home for if you have a question, we're going to find the person to answer it.Eric Rieger Yeah. And we're already starting to fill out that fill out that that schedule. So this this year should be quite exciting.Ken Brown Yeah. And if, if we can't find an expert, and we don't know the answer, Eric is gonna make it up.Eric Rieger Sounds so confident. that's a really good selling point. Let's get into it. This last weekend, I left I haven't even told you the story. I left the clinic headed home wanting to go and make the boys basketball games that were up in Wichita Falls. I got about 20 miles from home and suddenly, torrential rain going sideways hail. My phone goes off tornado warning. What in the world and it couldn't see couldn't see anything. And then finally it all passes everything's fine and to my knowledge no one was was hurt. There was some wind damage and a tornado spotted somewhere I didn't see it. But then the next morning Saturday, I wake up snow three and a half inches everywhere Ken Brown But it was like 70 degrees when that tornado was happening. Eric Rieger No Joke.Ken Brown And the very next morning, it snowed. Eric Rieger It was 24 degrees. The very next morning beautiful too. I mean, it was snowed very, very hard. And then by the time the afternoon came all melted, pretty much gone. I mean, that's amazing. Living in North Texas, especially. You just experienced a lots of different fluctuations in weather. There's no health story here. But it is kind of a treat sometimes you just kind of see everything. Ken Brown It is I watched last night as a family we watched because Rafa Nadal was on 60 minutes. They were interviewing obviously, we always talk about tennis and we'll get into the whole family thing but Rafa was on so the family wanted to watch the 30 minutes and I remember I used to watch 60 minutes with my dad growing up. Eric Rieger Yeah me too!Ken Brown Yeah. And I actually really enjoyed that. I didn't A lot of it I didn't understand. It was political and stuff like that. But I'd be like, 10 years old watching 60 minutes. So last night we were watching and they were looking at Florence, Italy. The canals. Dude. Up a lot. I mean, come on. We this weird climate change. We got Australia on fire. We got this going on. And they're there they're having hundred year floods, like every month. Eric Rieger Yeah, they're not hundred years anymore. Ken Brown No.Eric Rieger yeah, it's pretty wild. Ken Brown It's crazy.Eric Rieger I can't remember who it was. It said that they were there before the the water started. And like as they were leaving. And someone told me I thought it was some of you and I knew I've already forgotten. But anyhow, yeah, they were there and the last day of this day was was the first day that the water began to creep in towards the hotel. So that wasn't that long ago. But really interesting. Ken Brown It's It's crazy. I just saw an article today, where if we actually tend to have this, this climate change continues in this this pathway. Where now people are pretty much open to it now. Now we realized that okay, things are happening, the level of violence. So some epidemiologists were looking at if with each degree of worldwide raise in temperature, violence goes up and due to a lot of different reasons, and they had all these different reasons as to how that happens. But basically, we can become a more violent society with global warming. It's crazy. Eric Rieger Wow. Ken Brown I know. It's nuts.Eric Rieger Man, I don't even know how to answer that. That's wildKen Brown I don't even want to get into it. Because I just kind of looked at that. And I said, I'm already a little bit scared of where we're headed. I don't need to know that all of a sudden, we're going to become more violent due to it. That's like the last thing that I neededEric Rieger No, no. Yeah.Ken Brown I generally chill out when it gets warm. I like to you know, I mean, I like the heat. I sauna all the time so. Eric Rieger Yeah, we'll usually see people on the beach and their just laying down. I don't know. I'm not really getting it. Ken Brown This article described how we're just going to go around and violence will increase so...Eric Rieger Yeah it's unfortunate Well, do you have anything you want to hit on quick before we Oh, I've thought of something else but I'll go ahead and let you go first.Ken Brown Well, I was just gonna give a quick update with the family. Because this never happens in my house. We were all here. We did a whole lot of nothing. We... Eric Rieger Did y'all all know each other? Ken Brown We did. Eric Rieger That's good. Ken Brown Yeah. So the the kids at the last time that they're at they had one of those big giant Connect fours and so they ended up playing like the boys would play these are like, like the nation's best tennis players at that age and they're all were gathered around to connect for like an old school Connect Four that was like, like five feet tall. Eric Rieger That's awesome. I love Connect Four.Ken Brown So I ended up playing the kids a lot. In Connect Four on the on the computer. We ate out we found some new ramen places, and we chilled I slept 10 and a half hours last night.Eric Rieger That's not bad. Ken Brown I loved it. Heck, yeah. That's my weekend. How about you? Unknown Speaker All weekend boys had basketballs out is that talked about earlier Saturday night. I'm just getting older friend of mine, his daughter who I remember when she was really young. She got married. Really cool. Yeah. Whole family went and it was, it was a lot of fun. So shout out to Savannah and Rex. Just a great gathering of some folks, these these were really close friends of ours that he was transferred to Japan. And so he'd been there and I hadn't seen him since he been transferred there and his daughter gets married. And my brother was there my brother's close to this family also and it was it was a lot of fun. Ken Brown That's awesome. Unknown Speaker Yeah, yeah, it's really cool. Ken Brown You love seeing it maintaining friendships and relationships that far that you're seeing your your friends kids...Ken Brown And he just got transferred again. You know where to? Aww poor guy...Hawaii.Eric Rieger No awful for him. He and his wife are just hating it.Ken Brown Yeah. I finished the book Traction by Gina Whitman. Eric Rieger Yes. Nice.Ken Brown I took notes. I think I even sent you a copy. My notes are 28 pages.Eric Rieger You did. I'm behind you and I can't say that I know what all of your notes mean. But I think that they'll be good cliffs for someone who's gonna read it.Ken Brown What I love is every one of these people that in our entrepreneurial group baby bathwater every time I say Traction, they've all read it. They're like, absolutely necessary. So if you're a small business owner, try out the book Traction, the most updated one. Eric Rieger Sure, definitely, yeah. Ken Brown What were you gonna say? Eric Rieger So, I told you that I wanted to talk about 2-ag just briefly, but the reason is, and I, I can't remember exactly what study was, but that's not what's important. What's important is they were breaking down. Why do people smoke cigarettes whenever they become anxious? Ken Brown Cigarettes or marijuana? Eric Rieger Or was the marijuana?Ken Brown Marijuana I think. Yeah, because they're looking at the endocannabinoid system. Eric Rieger Marijuana cigarettes is what I meant to say. But that's what that's what they're talking about. But anyway, regardless, they're smoking marijuana, and why would they do that if they become anxious, and it has more to do with the increased production of 2-ag than what they had realized. It's not the only thing. It's just that they noticed that you increase your endogenous 2-ag and of course, if you're just tuning in anandamide and 2-ag are the probably the most prevalent endogenous cannabinoid we have. Ken Brown Certainly the most studied. Yeah so we make our own endocannabinoids and they're called anandamide and 2-ag. 2-ag stands for 2-Arachidonoylglycerol acid so 2-ag is easier. Eric Rieger Correct. It is that's why that's all that I ever say but I just want to pointed it out to you right before we started you said yes I think I saw the same thing. So what are your thoughts on that?Ken Brown Well, I just think it's so interesting because we always meet all these people are like, oh, there's no science on CBD. Oh, there's no whatever, no people we have an endocannabinoid system. We have been neglecting our endocannabinoid system and the articles that I'm going to bring up later probably show why in our endocannabinoid system we're deficient. So what this article looked at, is the fact that people are self treating. Now we know the molecule that goes up, that helps them deal with their anxiety. You know, it isn't like a it isn't like, oh, you're just running away from your problems? No, you're balancing yourself out by doing that. Eric Rieger Yeah, another interesting part though I thought about that particular article that I was reading there was referencing the study is that it was almost as if they were talking about 2-ag as just a substance, and then later talked about it as that it is it is an endogenous cannabinoid. But it, they presented it as if it was a newfound compound. And just just because of what we do, and I didn't really take it that way. I was like, well, you're kind of behind the curve. This isKen Brown Isn't that funny? Eric Rieger It's been a long time! Ken Brown Yeah. Because Yeah, I actually didn't read the article you called and told me about that. I'm like, that's funny, because they're acting like they discovered something. We've been talking 2-ag and anandamide for years now.Eric Rieger Right, right. Maybe Maybe it's just the way I interpret it. But that's the way it felt it felt like that they're talking like it's something new that they were trying to show correlation of this, this increase of this mysterious 2-ag and in truth, I felt like it was really just kind of establishing the importance of a healthy endocannabinoid system, which is really what I felt was my takeaways like hey, look, this is just yet more proof on why a healthy ECS is a great balance for somebody who is suffering from anxiety or, or something like that. You want to get that in in you want you want to keep your ECS healthy.Ken Brown Yeah so the endocannabinoid system what's interesting is that I'm I'd be curious to see if they did the exact same study with just pure CBD cannabidiol maybe you don't even have to smoke the marijuana cigarette as you say. And you just take CBD and then your body will adapt to that as well. Whenever people say oh, I take CBD and it helps with XYZ Well, one of the things is, I mean, we got a lot going on and I looking back in my life I've always run very anxious. Well, ever since I started doing the KBMD, health CBD, my anxiety 100% has been much more manageable, much more in balanced and I realized that Oh, that's probably one of those things as I'm running around anxious, my 2-ag is down possibly my ananadamide is down. All this is allowing me to do is just get back to my baseline.Eric Rieger Yeah, no, I agree. That it's something I didn't, I wasn't able to ascertain. Excuse me. You said I wonder if CBD could do that more than likely so and I was also kind of curious is what the mix was, you know because there's different strains out there for marijuana. And so I didn't I didn't know what they were referencing I highly doubt that it was probably one of those super efficient high level Maui Wowie things that everybody's clamoring for when they go out of a state that doesn't allow it to go and buy I really think that probably really like anything the more natural that something were to exist is probably where they're getting the benefit from but I don't know they didn't really...Ken Brown Isn't it so fascinating we just lump everything together. That's like saying hey, Eric, tea is Good for you. Eric Rieger What kind of tea? Ken Brown Exactly? So are you gonna take Elong which is going to have different black teas in it? Are you going to take chamomile which is going to calm you down.Eric Rieger Is lipton light green? Ken Brown Exactly. Eric Rieger It's not.Ken Brown It's you know, are we are you going to put a little packets of peak tea? Which our good friends peak tea, which They have polyphenols in there also and they promote that a lot. So I don't know why we discuss the marijuana plant like that because it could be that varied just like tea leaves. It could be so varied the cannabis plant and when we start lumping things together we just become ignorant to the whole process. If I say that to you will put you to sleep and you do a good solid green tea and you're up for hours. You're like, Well, that didn't work. I'm like no, no, that's not all tea puts you to sleep certain teas. Well, certain THC CBD combinations do certain things. Eric Rieger Definitely. Someone said I like apples. They may be a Washington Apple could a granny smith apple. It could be a Fuji. On and on and on. There's just a bunch of different apples.Ken Brown Now. Let's be I mean, let's let everybody know. I mean, you did your thesis on apples. I mean, I think it's I think you've been waiting forever. to unleash your knowledge of apples on everybody.Eric Rieger I can't wait until we dig into apples. Granny Smith for the win. Or honey crisp, those are great.Ken Brown You're just gonna give everybody all riled up? Let's move on politics and apples we don't talk about man. Eric Rieger Now we don't. Ken Brown You know, last week we talked about cell phones. Eric Rieger Yeah. Ken Brown We talked about people using cell phones while they're on the toilet.Eric Rieger We did we social toilets. Ken Brown Social toilets, how social is your toilet? Well, I just saw an article that just came out where a recent study looked at how people that take selfies, so they did a cohort study where they looked at people and they had them self evaluate. So it isn't like a randomized placebo controlled trial, but it is kind of very interesting, because we were talking last week about how people will post Instagram pictures and things like that. This study was really interesting, only in the sense that it makes that it's like, oh, duh. Because we always talk about how social media can actually lead to anxiety and depression. This study looked specifically At instagramers and selfies, and what they did is they interviewed It was 164 female students at a public college in the southeastern United States. And what they did is they surveyed a photo manipulation and selfie tapes. And what they realized is that these women were having this body surveillance issue where they wanted to have the best picture the best selfie that they put up there. And most of the participants reported taking between two to five selfies before publishing the one, many of them or I shouldn't say many, but a large proportion that actually had depression would take up to 20 pictures before posting the one. And there's so many filters that you can do now you can take out blemishes, you can augment certain body parts, you can do different things. And what they showed is those who took more selfies or manipulated he pictures had significantly higher levels of depression and anxiety. Eric Rieger It's not that...Ken Brown Isn't that interesting? Eric Rieger It's interesting. But is it really that surprising? Ken Brown Well, that's the thing. It's not that surprising. And when you sit there and look at this, and when people go, oh my gosh, she's so beautiful. Oh, she's got all these likes or whatever. The reality is, you can't run from yourself. There's a certain disingenuous portion of you that knows you kind of manipulated it.Eric Rieger Yeah. Without question. And here's a, just a quick side caveat here. Remember, before we had the digital availability of photos, and we just had film, there wasn't the instant gratification of going over and making certain that the picture that was just taken was perfect. You just took it. And then you went to the photo mat at some point. And then it was exciting to go and get the envelope with the pictures and you could thumb through them. And you always wanted it before the girl who might also be in the pictures because she's gonna discard the ones that she doesn't like. Remember that? I mean like you would say, let's go get the pictures. Oh, I'll go with you. And then she grabs them and I can remember, you know, people grabbing the photos like, oh, and then keep that one. What is that? Oh, you don't wanna see that? That's the old way of discarding photos that you didn't want seen. So now you can take them without with it doesn't matter. Does it cost anything take more pictures. So interesting that technologies actually probably lent itself as a as a tool for someone who may have anxiety or depression to kind of make the situation worse. Ken Brown I mean, I challenge everybodythat if you're gonna post a selfie, Eric Rieger just do it. Ken Brown Just do it. Make it real. Do the funny face everything because we spent so much time trying to show this curated life that I have. I want you to believe that my life is this. I mean, one of the fun things about doing this show is we don't edit anything. Eric Rieger No! Ken Brown It just happens. Eric Rieger I just said cigarettes and I meant marijuana. So yeah, no, he did that. But that's not really I promise you, your friends like you. And if you're listening this your friends like you because you're you not because you, you practice or rehearsed a line before you saw them, they just want to hang out with you. I mean, and you should be, you should be confident that that's what people are after.Ken Brown So this, this particular study essentially just showed that even though so here's what's happening. You have people that are taking multiple selfies, they're trying to find the perfect one. When they post it, then all they do is wait for that dopamine rush of a like, of a like of a like, and then if this one doesn't get as many likes as the other one, then what do I do? Do I go back and do this? The bottom line is we want to be part of a community. We know that deep down when you want that like it's because you want to connect with somebody. Unfortunately, when we have these social media platforms, it really waters it down so that you feel that you get a little dopamine release but you don't get the serotonin which is your true happiness molecule. Dopamine is your pleasure molecule. So you cannot have both going on serotonin and dopamine, because that's how come the whole rock star phenomenon you keep chasing that dopamine high. So what I want to offer to everybody here is take a selfie, don't put a filter on it, send it to us. Connect with us at KBMDhealth on Instagram or on Facebook with a gut check project.Eric Rieger Gut Check Poject on Facebook Ken Brown Because I can tell you right now that if you are lonely and you are not connecting with people on a one to one level, it has been proven to be as dangerous as smoking. Smoking the cigarettes. Like you were saying earlier.Eric Rieger Yeah, I got things inverted there. Ken Brown The cigarettes...So it's I just find it so fascinating that we have this so you just got done telling me a story about how people smoke or they they seek out marijuana and Now we realized that there is an Endocannabinoid that they're trying to compensate with with 2-ag. Well, dude, any type of stress like that any type of thing. So now we know that by doing selfies, and waiting for that dopamine kick, you're creating anxiety and depression, probably related to a depletion of 2-ag as well.Eric Rieger Interesting. It really is. I don't, I wonder, I wonder what could be done for somebody to kind of wean themselves of, of hunting for the the digital likes, I really just ignore social media for the most part, certainly on a personal level, I don't find it rewarding. In some instances, it's kind of depressing. I like going to social media when I feel like I want to catch up with someone or that honestly, we need to find a new way to to make sure that our audience or our patients is are getting the right information for Atrantil etc. But I don't, I don't look for it to give me any type of gratification and but I think that I'm maybe the anomaly for someone who's connected like that there's maybe even my kids who don't necessarily maintain their Instagram. I know that they keep up with their friends on it. And they see pictures, and people share them. So how would you wean yourself from that kind of that kind of environmen if you already didn't have the biological systems in place to help you do that?Ken Brown Dude, that is a great question. I'm not much of a social media person. So I'm not really down with that. We're gonna find a psychiatrist or a psychologist that specializes in this. There's that great YouTube video, where I told you, you made your kids watch it. I made my kids watch it, where it's a Harvard psychologist discussing the fact that when we give kids phones and they get into social media that that dopamine release...When somebody has a hard time at school, your seventh grader has a hard time at school. They come home And they're upset about something and then you let them have their phone. That is exactly like giving them the keys to the liquor cabinet. You had a tough day. Why don't you go cope with it by having a few vodka sodas or whatever. And we think that's crazy. But we don't think anything of let your kid go to the room, sit on their phone and go into a spiral, because they're not part of the Snapchat group that that they were excluded from because X, Y and Z. It's, it's really from a parenting standpoint, it's really hard to sit there and walk that fine line between I don't want my children to be the weird kids that don't have any social media involvement. But I don't want to allow that giving them the keys to the liquor cabinet, where they're just trying to supplement their dopamine kicks with how many likes they have because there's a lot of science going on with this.Eric Rieger Yea and true confession I think that we screwed up its parents that I'm talking about me and my wife. Well, we, we gave the phone the phone breached in probably far too early. I mean, that's just that's just the truth. We've done a good job of monitoring how well I say we're doing a good job. Maybe they'll maybe they'll hear this and they'll laugh. Ken Brown I don't think you guys. I don't think he has waited too long when I saw gages...His,you know I went to his one year birthday party and you gave him the iPhone 2. That's not early! Eric Rieger He's not quite that young but yeah. But, I mean, looking back, I wish that we had had held off longer than we did. I don't think that we did anybody any favors by doing that. Heck, I wish I had never gotten into a smartphone. It's almost like a weird codependency issue now, like, I want to get to the point where I can just go back to a flip phone and no phone at all. But...Ken Brown There's always Yeah,Eric Rieger Like most I mean, I don't think that I'm alone. I mean, I know I'm not because we see it every day with the patients just before we take him back to let them go to sleep. They want to they want Want to take that last time before they go to sleep? And before they stow their phone? That's it's very common every single day.Ken Brown But we're just keep seeing new and new data like this particular study. Everybody else that looks at those pictures probably goes Oh, she's so pretty, she's got an amazing thing. Eric Rieger And the person who's in it probably hates the picture Ken Brown And the person who's in it is just critiquing themselves and they're becoming and having more anxiety and depression.Eric Rieger Oh, yeah, it's and it's it's, it's unfortunate. It's not fair.Ken Brown I had a remember our guest with short path wealth. Tim Tim power. He he posted something where it was like the next time you're having a bad day. Remember this is going on. And it was a picture of 250 Amish men carrying a barnEric Rieger Yeah. Yeah,Ken Brown I'm like there's easier ways to move that barn. But that's cool. Eric Rieger There are and they're not doing it, but they're probably not nearly susceptible to depression.Ken Brown I looked at that and I was like, that's community. That's coming together that's busting your ass that's getting out there. There's a certain amount of okay. Yeah, there's easier ways to do it. But okay. Eric Rieger The initial reaction is to laugh. The truth is they're probably pretty happy. You know, isn't that wild, but it's just true.Ken Brown Yeah. I thought that was interesting.Eric Rieger Yeah, it is. It is interesting. So what else you got?Ken Brown Nothin? Um, we can get into a few things. You got water?Eric Rieger I'm having a little austin texas Waterloo, Ken Brown Ah a little Waterloo. Would you like to sip from it from this cool, straw.Eric Rieger I mean, I traditionally don't use...Ken Brown No don't do that at all, because that's what we're going to get into right now. Eric Rieger That is rude as hell.Ken Brown That almost killed you. Eric Rieger I did not know that. Ken Brown Ah, well, let me tell you what. So we uh, we have the distinct advantage of course we have our little our secret weapon.Eric Rieger If you're just listening. He just offered me a straw and threw it across the room just so you know.Ken Brown Well, here's why. So You know, we have our, our amazing graduate student that always helps us out. She sent me some incredible articles. Two of them came together. It's super geeky, hang in there with me, please. I'm going to get into what's gonna sound like a lot of crazy words, but this will blow your mind. I cannot believe and she sent the email. She's like, this will blow your mind. I cannot believe that. We have not talked about this yet. And I'm like, okay, two articles recently published that holy cow Hang in there, because it's gonna sound like, well, pretty much you're screwed. But I'm going to give you a solution at the variant.Eric Rieger I can't wait. Ken Brown All right.Eric Rieger Yeah. Ken Brown And probably most relevant for you, Mr. Eric, Mr. crna. I'm telling you, you probably need to hear this more than anybody more than anybody, anybody more than anybody. More than anybody more than anybody.Unknown Speaker I'm all ears now. Ken Brown All right. So, all right now we're getting into some serious science. You know, I love to geek out about this stuff, and hopefully I'll be able to hopefully I interpret it well enough. And hopefully we'll be able to make some sense of this. But what we're going to talk about is a recent review on the toxic effects of Di-2-ethylhexyl phthalate.Eric Rieger Yeah, that usually doesn't come up very often.Ken Brown Or DEHP. Which From now on I will refer to as DEHP. As inJohnny Depp, but it's DEHP, so before you sit there and go, Oh, I've never you know, this doesn't pertain to me. Oh It really does because as it turns out, DEHP DEHP is the most common member of phthalates. Now, phthalates are mainly used as plasticizers. Eric Rieger Here we go. Ken Brown There's substances added to Plastic, specifically PVC to increase the flexibility so that death straw that I just tried to offer you filled with DEHP. Okay, what it does is it softens the PVC so that anything is flexible. Eric Rieger Okay. Ken Brown So you start thinking well, like due to the ubiquity of plastics everywhere. The majority of people are exposed to some level of phthalates. For example, the CDC actually took a large cohort of people, and they looked for the metabolites of ballots, and everyone had them in their urine. Eric Rieger I'm sure. I'm sure they do. Ken Brown It's almost unavoidable over 2 million tons of this stuff is is produced worldwide. And I don't know why. I don't know how we've not discussed this already. Why this has not been talked about. Do you know anything about this? Eric Rieger No, I don't know anything about specifically this particular compound. What I'm really thinking about right now is the abundance or ubiquity of all of the plastics that are are flexible now I mean, I'm just thinking if we're going to panic, your water is certainly in a modern home is is usually channeled by PVC. And that would be I mean, it's...Ken Brown well as long as it's PVC until it becomes flexible. You're not getting DEHP.Eric Rieger Okay...Ken Brown But this is why it's really relevant to you. Eric Rieger Oh okay? Ken Brown And to me but more to you. Eric Rieger All right...Ken Brown Guess what? Tt's especially used in medical devices.Eric Rieger Oo like endotracheal tubes? Ken Brown Oh way more than that endotracheal tubes, IV bags. Yeah, keep going. You're getting it.Eric Rieger Goodness gracious IV tubing IV bags, you could the catheters that we start the IV. Man, the anything that would do seldinger technique with is going to utilize that right?Ken Brown 100% Eric Rieger Holy crap.Ken Brown Holy crap. It's everywhere in the medical industry. Eric Rieger Probably the non latex gloves that we have to substitute for people who have latex allergies.Ken Brown All of a sudden you start looking this you're like, whoa, wait a minute...Eric Rieger Nasal canulas! Ken Brown Nasal canulas. There you go peritoneal catheters, you name it, you know, typical catheters, urinary catheters, anything, because everything we use on humans has to be flexible. It has to be able to be malleable and stuff. So as it turns out, you and I are exposed to tons of this.Eric Rieger Yeah, every single day, every single patientKen Brown You more than me, Eric Rieger Yea probably so.Ken Brown And then we're sitting there doing this with a patient. So.Eric Rieger Interesting. Ken Brown Yeah. But you know, what, if everybody's listening, and they're just like, well, I don't work in the medical industry. Too bad as it turns out, packaged foods, those bags that are flexible, so it's not a stif little thing. packaged foods, it's in packaged foods, it's in mattresses. It's in cosmetics, personal care products, high concentrations in fatty meats, and even bread. Eric Rieger Why is that? Ken Brown It's just it gets concentrated in fatty environments. And so when they when they had the plastic bags around the bread, the bread soaks it up. Now we're eating it. Eric Rieger Hmm. Ken Brown So when we take in this DEHP, the only thing cool about it is that it gets converted into something that I'm going to start using as my stage name from now on, it gets converted into Di-n-octyl phthalate otherwise known as DNOP.Eric Rieger DNOP.Ken Brown DNOP now, DJ DNOP coming on.Eric Rieger Here on the Gut Check Project here's your host DNOP.Ken Brown Yeah. So why do you care about DNOP? DNOP coming on! Well, as it turns out, look at what this little molecule actually does to our bodies.Eric Rieger Uh oh.Ken Brown Uh oh is right. I mean, when I was when I was reading this, I'm just like, What in the world? We are, and this is a worldwide thing. This is not US. This is not race dependent. This is not anything. Now. I'm going to spend little time here and I'm just gonna tell you what, well, I'm scared for you because you're around IV catheters, you do this all the time. Eric Rieger A lot yeah.Ken Brown Yea. All right, DHEP. It's best known as an endocrine disrupter. What's the name of the mindshare? Jolene? Eric Rieger Oh Jolene Brighton? Ken Brown Yeah. And then yeah, so anyway, so that yet, I'm sure that she's probably going, duh, we know about this. This is one of those things where you're just like, I guess the bandwidth is only so big, but we can get. I bet you a lot of functional medicine doctors are just like going, Oh, my gosh, we've been talking about this forever. So all right. It's an endocrine disrupter, what that means is it will alter the function of the endocrine system exposure in utero. So this is what's really crazy. If you're pregnant, and you expose your fetus to this, it does tremendous things. One of the things that it's that it does is it actually decreases testosterone production and messes with the estrogen cycle. In fact, they have studies that have shown that exposure in utero leads to lifelong testosterone issues. They have taken adult rats, and they looked at them when they were exposed in utero. And they have shown that their testosterone is markedly lower, just from one exposure in utero, for their whole life. Eric Rieger I wonder if it blunts like teste development and that's probably why interesting.Eric Rieger Interesting. Ken Brown They have all kinds of different reasons why like this, these articles are super sciencey. And they get into the molecular mechanism of it all. And I'll get into a little bit more about this, but I'm going to show you this thing is going to blow your mind because what they did is they they looked at this and they showed persistent low testosterone in adult rats studies. Now rats fed a diet with DEHP also have serious lifelong thyroid issues. So the theory on this is it's an epigenetic phenomenon. So in other words, if you expose a fetus in utero to DEHP, which is everywhere, then it can turn on an epigenetic phenomenon, meaning that there are certain genes that get turned on. And then that becomes the new norm. That's how come they proved that you can sit there and have low testosterone for the rest of your life. That's how come you can end up with thyroid issues when you become older, because that transcription of the genes has been turned on. Ken Brown You need to that's the epigenetic phenomena. Epigenetics means that you have genes you're predisposed but then if you have an environmental factor that comes in, then that actually turns that gene on. Well, as it turns out, DHEP does this to people significantly in utero. So they looked at elderly people and it suggests that insulin resistance is actually due to DEHP or DEHP sorry, so insulin resistance so diabetes. Chinese studies have looked at children and their BMI goes way up when they have higher levels of this metabolite in their urine. There's all kinds of studies on this where it's like, oh my gosh, you mean the incidence of diabetes incidence of thyroid, the incidence of hormonal issues is going up? So that's one example, endocrine disrupter. So I thought about this when I read this. I thought about you when I read this. Eric Rieger Okay. Ken Brown What you think would happen if I give homage to do you remember the article we did about liver failure?Eric Rieger I do remember gavaging CBD Yes,Ken Brown Go back to our episode 26, go to Episode 26. And we talked about garaging which means that you're going to stick a tube down a mouse and put in copious amounts of... Eric Rieger The title was CBD causes liver failure,Ken Brown So they gavaged some poor rats. And can you guess what happened to them?Eric Rieger With that?Ken Brown Yeah, with with basically DEHP. DEHP I'm I'm just going to call it DEHP from now on. Eric Rieger Well, I think that if you're going to gavage DEHP and since nothing is sounded like it with the favorable I would imagine they exploded that they turned into robots, but maybe not as bad. Ken Brown No, it's worse. Eric Rieger Oh, okay.Ken Brown It's worse. What it did. Cause testicular atrophy just shrunk their testicles. Eric Rieger Wow.Ken Brown Basically made them not men. So I was. I mean, you and I've talked about this, but if you ever end up in a situation where your testicles are too big.Eric Rieger Oh yeah. Ken Brown And I find you chewing on some IV tubing, I'll know why. Eric Rieger You'll know why Yeah. Ken Brown I'll know why. Because you're trying to control the size. Eric Rieger You don't want them too big. It's craziness. Ken Brown You just sit there nawing on some IV tubes.Eric Rieger Yeah, yeah, it's gonna get some some space in the pants.Ken Brown I mean, think about that you they can actually show that it causes such a disruption in the testosterone pathway and the hormonal access pathway that you will actually end up with testicular atrophy. You will not have testicles.Eric Rieger What's interesting is I'm curious how, how prevalent is it beyond the those of us in the healthcare environment for people to be exposed to DEHP Ken Brown So glad that you asked that. We're going to go through and now we're going to talk about so so far I've kind of focused on the thing that that concern me Sure. testosterone and you know, the Eric Rieger Work environment? Ken Brown Yeah, work environment. But it also looks like it. It does all kinds of stuff. It'll mess with ovaries. This is really interesting. It seems to increase endometriosis.Eric Rieger Oh, wow. Ken Brown Yeah.Eric Rieger That's terrible.Ken Brown So I see a lot of patients that have a ton of pain. And they did a study where they looked at Indian women and that had endometriosis. And they checked their DEHP metabolites significantly higher than their non endometriosis counterparts. Eric Rieger Goodness gracious. Ken Brown Yeah. And it appears that the reason why that happens is due to our old friend oxidative stress.Eric Rieger Wow,Ken Brown Just park that one and let's Let's come back to that for a moment. Eric Rieger Okay. Ken Brown So it's due to oxidative oxidative stress. Oh, this is this is really fun. This is neat. So as it turns out, it's nephrotoxic.Eric Rieger None of this sounds good. Ken Brown It's Nephrotoxic. Eric Rieger That's bad for your kidneys.Ken Brown Holy cow. Now they decided to look at dialysis patients. Guess who gets exposed to all Kinds of medical tubing? Eric Rieger I mean, they're getting they're getting new tubing every time they go in.Eric Rieger Every single time and most dialysis patients are three times a week for four plus hours each visit.Ken Brown How did I not hear this? They've looked at this. dialysis patients have some of the highest DEHP levels metabolites. Ken Brown Think of that dialysis setup and all of the tubings that go into the cartridge. Remember the cartridge that goes on there with the new membrane, all of the flexible tubing that's on there. Ken Brown It's crazy my dad did peritoneal dialysis and I mean my gosh, it's it's tubing that's in there. You're bathing yourself in this And I'm just telling you that it can already mess with your endocrine system, it can already be nephrotoxic. So if you had any chance of recovering your kidneys, then you're just you're stacking the deck against yourself. Eric Rieger Okay? And maybe we'll get to solution here in a moment. But at the moment, I'm curious, what are the alternatives outside of what we're doing now, I guess.Ken Brown We will get there. Okay. And that's something that we're going to do. We're going to develop the KBMD bubble to be like the bubble boy. Yeah, we're gonna we're gonna launch that. We're not gonna do that. We're gonna we're gonna get into all those. All right, but let me if you're not already scared enough. Yeah. And you're just going, Okay, well, you know what? Screw that. I don't really care about my testosterone. I don't care about endometriosis. I'm not on dialysis. Not a big deal. Well, there's one thing that we all have. There's one thing that you and I talk about all the time, the gut brain access. Yeah. So as it turns out, we all have a gut brain. Yep, your brain takes a hit Also. Eric Rieger I'm sure. Ken Brown Your brain takes a hit also, essentially If it's exposed now I'm going to keep saying the same thing over and over. The younger you are when you're exposed, the more damage it does. And I'm going to get to this because spoiler alert autism. We're going to get to that a little bit. But so your brain takes a hit. Also, it can disrupt the normal fetal brain development, it appears to mess with the hippocampus. So the hippocampus is the area of the brain that's super important for memory and spatial recognition. Very important. And it's, it's for the spatial navigation. So if you can get through the fetal exposure of it, then throughout your life, the more exposure you have to it, so in other words, the more flexible plastics you're exposed to it does something really interesting. It decreases your BDNF. Eric Rieger Oh, no. Ken Brown Yes. Do you remember what BDNF is? Eric Rieger The brain...goodness gracious I don't remember exactly what it stands for but it's exactly but that's exactly what we talked about for brain plasticity. Ken Brown Correct. Eric Rieger Yeah. Ken Brown Its brain derived neurotrophic factor. That's right. Eric Rieger Sorry about that. Ken Brown No, it's but you and I have we've always talked about this because remember when we heard David Perlmutter give a talk at Helio Fx?Eric Rieger That's exactly who I was thinking about.Ken Brown He was talking about how coffee fruit had a very small study where it showed it increased BDNF. Well, as it turns out, BDNF can be increased by a lot of different polyphenols. BDNF is the protein in your brain that allows new neural connections. Eric Rieger Yeah, all the DEHP I've been exposed to made me forget what BDNF actually stood for.Ken Brown And we also believe that one of the reasons why there's a lot of dementia is because we lose our BDNF and we do not grow new cells, right. So as it turns out, BDNF decreases. Oh, it appears that it decreases because of reactive oxygen species developing in the brain leading to oxidative stress.Eric Rieger So it sounds to me like what DEHP is if I'm connecting the dots here is going to be catalysts for oxidative stress. And so what we're going to need to do is if we can't eliminate DEHP from our environment, what can we do to mitigate the oxidative stress? Correct? Ken Brown Correct. We're going to get to that. All right. Yeah, you're you. You've already you've already made the links. So if you're, if you're still listening, and you want to learn how to do that, what Eric just described is exactly what I want to tell you how we're going to do that. We talked about depression and anxiety. They looked at a study, I mean, I just cannot believe how much data is on this stuff. They looked at a study at pubertal females they did some mouse models and then they correlated it with some human studies as it turns out, the more DEHP DEHP that you're exposed to you have more anxiety and depression.Eric Rieger Golly Man, what a it's a large manifest of a bunch of different things. And I don't know that you can escape flexible plastics. We just you just said if PVC were flexible, then maybe would have it actually was reminded, as I thought about that in our last home. When we, when they ran the cold and hot when we built the home, they ran flexible tubing on off of a big spool blue for cold and red for hot because they don't run pipe through foundations the same way anymore. No down here in Texas. Ken Brown oh, because it shifts.Eric Rieger Yeah, it can shift Ken Brown it can bust yeah Eric Rieger So many times they run it overhead through, you know, the whatever they call it the attic or whatever. But essentially, that's flexible plastic. And if you're drinking water from home, it's going to I would imagine it's leaching in there, correct? That's how it's happening.Ken Brown Well, once again, the CDC looked at people and almost everybody has the metabolites in the urine. It is and it's not it's worldwide. Um, alright, so we'll finish up with I mean, clearly it's already scary, right. So... Eric Rieger Yeah, definitely. Ken Brown There's also the article goes on to a molecular reasons why how it messes with the liver and it messes with the heart. And, oh, it's linked to autism. The autism and they Kind of briefly talked about it in this article and fortunately, our graduate student knew that I'd be more interested. So she sent me a follow up article recently published even, I mean, these things are all being published like a week ago, like we get them in, like pre transcript. She's amazing. And so she sent me another article that actually talked about this specific thing. But now it's right in our wheelhouse, right in our wheelhouse. So don't be scared. Because now we know that we have this ubiquitous plasticizer that clearly is very toxic. We know it's toxic, we know what's there. And it's used in healthcare all over the place.Eric Rieger Everywhere. Ken Brown So right now there is a movement currently going to try and get rid of this, we know that it's bad. So over the past 10 years, people have been trying to do this, but since it's everywhere, it's gonna take some time to get out of there. And it's sad because as you know, sometimes medicine is not the fastest to change for some of this stuff, because of contracts and blah, blah, blah, blah, blah. So we're always trying to find so right now there is this movement to try and use PVC free alternative polymers like polyethylene. So there's hope we're moving away from it. So when you said, Well, what, what can we do, but while we're here, I'm going to try and help you out with this. So I wanted to dig deeper in this because we know that autism is such a hot topic. If you're a parent with a child with the autism spectrum disorder, ASD, then you'll do anything to try and try and help...Eric Rieger It's your kid.Ken Brown It happens to be a passion of mine, or at least a passion in the sense that my aha moments of seeing some of my autistic patients improve mentally when we went when we fixed our gut. Yeah, I mean, I see it and so I'm very passionate about this. Here's what's really neat, this article. I mean, I just, it's almost like some of these. It's, it's like, I want to go and hug some of these scientists. So the whole article goes into how DEHP predisposes and leads to autism spectrum disorder related to drumroll. The microbiome.Eric Rieger Microbiome! Ken Brown Yea.Eric Rieger Nice! Ken Brown So we've we've these articles hit on everything that I love to talk about.Eric Rieger So heal or protect yourself and the damage DEHP by taking care of your gut.Ken Brown So this is so cool. So studies have shown that exposure in utero, in utero to toxic chemicals can lead to dysbiosis in the fetus. Dysbiosis by definition is basically a change in the microbiome, but not for the better. So you can have too much of one thing not enough of another, you don't have enough diversity. dysbiosis by definition just means it's not right. your microbiome your microbiome is super important. In fact, a recent study showed that children with autism spectrum disorder had higher concentrations of DEHP DEHP, but more importantly, they also looked at fecal samples of these kids with autism, and they had higher levels of a metabolite called P kressel.Eric Rieger P Kressel? Ken Brown This is how dialed in, we're getting into this. Now. Now we're talking about something that they looked at these autistic kids. And they said you have more of this plasticizer in your body. In addition to that, we're going to look at your microbial content, you've got dysbiosis, and you've got this one metabolite called p kressel. So as it turns out, when you have this dysbiosis, the bacterial composition can either be harmful or beneficial. So these scientists show that the link between bacterial metabolites and neuro developmental disorders are taking place. So they actually then use that knowledge, took it to mice, gave them DEHP, and then analyzed their microbiome. So the whole shift went from, oh, it does all this end organ damage. So I just told you that if you gavage yourself, you're gonna end up with testicular atrophy, I just told you, you're gonna have endocrine disruption, you're going to end up with liver problems, heart problems. Now these guys are looking at it going well, wait a minute, we're exposed to this all the time. Why do some people get it? Why do some people don't?Eric Rieger Yeah, they're controlling their inflammatory.Ken Brown They're controlling their inflammatory process. Super cool. And so what they did is the most important thing, when they looked at these mice is that the older mice with a more diverse microbiome were completely protected from the effects of DEHP. Eric Rieger Interesting. Ken Brown The most important factor was that and they showed that there has been studies in autism spectrum disorder, where an overabundance of a Clostridium species was linked to autism. So possibly by not having the age protection where you developed a diverse microbiome your entire life, and not having a full microbial diversity to do the post biotic metabolism, of these in virus mental toxins. That may be why when we expose children to certain things that could turn on the epigenetic phenomenon, or more importantly, these bacteria are now producing this P kressel. Which then shows that they're being exposed to DEHP, which could lead to autism spectrum disorder. Eric Rieger Wow. Ken Brown It's the first time I've come across an article like that. I'm like, holy cow, how in the world that I just read this article on plasticizers. And she found this incredible article linking the microbiome to this. I mean, I mean, this is, I mean, it's really hard to not geek out on this. We know that the bacteria your microbiome, actually does an incredible job of breaking down toxic metabolites of all kinds of things, including DEHP. Now we call these toxic metabolites and we call these different things. xeno biotics, that's spelled with an x xeno biotics are molecules that get through your body and then your own microbial background, your mind microbiome breaks them down. And if you have an appropriate microbiome, then you can, your body can be exposed to some stuff and handle it, right. But when we start exposing kids in utero, you're stacking the deck against them right off the bat. That's what's super scary. So one of the things is that you can show a dose dependent process where they even took these mice that were that were impervious to some of the effects of it. But at some point, the bacteria got overwhelmed. And then the DEHP cause dysbiosis and then they got sick. So once you took enough of it in, then you couldn't keep up with it. It's really I mean, it's, it's, it's dose dependent. So you can't just say, Oh, I'm gonna let my microbiome do everything. You still have to realize that at some point, you can overwhelm it. So just keep that in mind. So taking together DEHP can be neutralized in a mature diverse microbiome. So if p kressel is produced this has been linked to autism and they showed an overabundance of a particular Clostridium will actually convert and they even went so far as to show we've determined that the amino acid tyrosine will be converted by p Kressall by this Clostridium species. Whoa! Thik stuff. I'm sorry, I threw all this at you, but I just got super geeked out when I was reading it, and I just found it fascinating. So just to summarize, flexible plastic like that straw that I tried to kill you with has a compound in it called DEhp. DEHP gets converted to D NOP! D NOP. And that hurts you. And what we do know is that most of the end organ damage happens because of oxidative stress. Eric Rieger Wow. But you can control that. Ken Brown We can control that. Yeah. How would you control it? Eric Rieger Well, you you hit on a few things. You want to make certain that your microbiome is certainly well diverse.Ken Brown One! Eric Rieger You could do that with a reasonable diet, you can do that with making certain shift good exercise you could also do that by giving your body the appropriate level of polyphenols that it would help make that happen. Just so happens Atrantil I think, would be a great proanthocyanidin polyphenol to to assist in that. You also want to be able to handle the stress load. So handling the stress load the oxidative stress. Allowing your body to not be overstimulated from stress would be something that you could do to to do that. So polyphenols, by some level, handled that directly but not having your body overstressed to be something that you would want a healthy endocannabinoid system. And that way you could handle stress and oxidative stress wouldn't play into more of a cascading effect that turns into an inflammatory process for your organs and tissues. So starting with those three things diet polyphenol intake exercise and actually four CBD, I think would be a good start.Ken Brown Yeah. You're exactly right. So while we're on it, one of the things I'm super proud of, is thatEric Rieger Oh, look at that.Ken Brown We have the KBMD health subscription box. We do. Let's unbox it. This is this month box just arrived Sarah Jean sent this to me. I actually subscribe to my own box. And now you're gonna fairlight I'm gonna let you just pick the ingredients out here. This is the box. Your health has arrived. We'll start out with our main products here. So basically, the box comes like this. My kids w

How social is your toilet?

Play Episode Listen Later Jan 9, 2020 66:28

Eric Rieger All right, you have now joined the gut check project. This is episode number 27. I'm here with your host, Dr. Kenneth Brown. I'm Eric Rieger. It's 2020.Ken Brown We're in a new decade. This is unbelievable.Eric Rieger So that's interesting. Some people will say that the decade does not begin on years that end in zero, because when the calendar started, there was no Year Zero. It was let's have a year this is year one. So lots of people end up saying technically a decade doesn't start to the ones but nobody talks that way. When you say the roaring 20s it started 1920. So I'm on board with you. I think this is the beginning of a new decade.Ken Brown How did you...I mean, how could you say when you were born when it was BC, were you like I'm minus 20?Eric Rieger Yep, that's pretty much what they did. Ken Brown Is that what they did? Yeah, they'd just walk up...Eric Rieger In 745 years they will begin to count. I think that's how it went down.Ken Brown Is that how the whole the whole calendar went down? Like All right, everybody, we're starting over. Eric Rieger Yeah, y'all are gonna love this. There's gonna be a Messiah. We're gonna start counting it's gonna be great. Ken Brown I love it. Eric Rieger Well, today's episode of course is brought to you by Atrantil developed by the guy right across the table from me Atrantil is a daily source of polyphenols to address issues of symptoms related to IBS, as well as definitely bloating. Ken Brown You know what I'm really getting into also is all the new information coming out with polyphenols in sports performance. Talking about how polyphenols actually can improve blood flow by increasing nitric oxide. I can't wait till we can start working with some endurance athletes and start testing them to see if we can get some new prs and some of these people.Eric Rieger Hundred percent! Ken Brown If you're running some marathons. If you think about it, if you're an endurance athlete, like a triathlete or something, you know, I got my good friend Ron Tribendis who has his own podcast also tremendous chiropractor and he's like high level performance and all that he actually sells Atrantil. But we were talking about that, that, you know, he gets so many of his clients that he trains and that are his patients that when they start training for these triathlons and marathons and they're taking in all that goo and the high fructose stuff to try and or not even just the fructose based sugars to try and gain fuel from it. That's when they start having gi distress. I feel like we can help all those people.Eric Rieger Definitely it's interesting that you bring that up right off the bat because at CPSDA and the reason why this is important is Atrantil is chock full of polyphenols. That's where the magic is. So that's why discussing Atrantil leads us to talking about athletes and when I was at CPSDA about a year and a half ago. Joe VotelKen Brown The PhDEric Rieger The PhD from Exeter University over in Europe. She came over and they've done extensive research on multiple different research opportunities where they've shown that daily polyphenol intake and athletes will decrease recovery time, increase blood flow, just as you pointed out, increase nitric oxide production. These are things that serious athletes love to know. And it's, it's natural. Even more importantly, though, you can always say, get rest, or eat polyphenols or have some fruits. But ultimately, when someone wants to do it, it's how much? And she was able to show that pre no, I'm sorry, proanthocyanidins, at 1000 milligrams per day was an optimal dose for active athletes. So anyhow...Ken Brown If you want it to get that, I mean, what would I have to eat? If it was like cherries or something. Eric Rieger If you wanted to have that. This was her example. It's awesome. She showed that you would probably have to have four to five bowls of cherries or blueberries. Good fruits. Unfortunately, there's a lot of high fructose or not high fructose. There's a lot of fructose that's in there. And serious athletes oftentimes don't want to over load their daily sugar even if it happens to occur naturally now-separate debate. But she she quickly pointed out that if you could consume proanthocyanidins that did not have high fructose content, you'd have something magical and just so happens that Atrantil four capsules roughly equals 1000 milligrams of proanthocyanidins...Ken Brown I've actually had a lot of patients tell me that they do better. Oh, one thing we're going to start doing in 2020, and we're going to go back. Let's just do a little disclaimer here. Although I am a real doctor. Eric Rieger Yeah. Ken Brown Do not take this as medical advice for that weird rash or that unusual, extra toe growing out or something. Go see a doctor, don't listen to us. We're here to have fun, possibly educate a little bit but more importantly, help everyone to discover some new things because that's what we want to do. We want to find new things in the literature, new things that are coming out and make sure that everyone can biohack in the way that we have tested on ourselves. SoEric Rieger Definitely. So find Atrantil at antrantil.com or lovemytummy.com is much easier to remember, forward slash kbmd Atrantil lovemytummy.com/kbmd. Not just for bloating, it's also for athletes. It's really for everyone.Ken Brown It really is. And so that's how I mean it's...this is fun. In fact, this brings me up to something so I just shot a video for this. We have a new website that has launchedEric Rieger finally,Ken Brown Finally! So go to kbmdhealth.com. Check it out, give us your feedback. There's going to be a video there where I kind of get into the things that I like the things that I like our biohacking CBD, I'll try and deal with polyphenols and making sure that you can have access to some of the best vetted supplements meaning a lot of the stuff that people are buying may not actually benefit you or may have something dangerous in it. In fact, there was um, I need to find out what she had. But there was a news article here in the DFW Metroplex, a very unfortunate 23 year old, who was taking some woman's multi weight management. They didn't say the name of the product or what was in it. Eric Rieger Sure. Ken Brown But unfortunately, they believe that that actually caused daily drug induced liver injury. So that's one of the things when I've had patients come in, and you find out that they're on a supplement, but that supplement is not third party tested or that supplement is coming in from someplace else. Anything can happen to anybody. I understand that you can have a bad reaction, you can have an allergic reaction to something but make sure that you're at least if you're going out trying some different things to make sure it's third party tested, which is why we have the kbmd health subscription box. Eric Rieger Yeah, we, definitely you can find that health subscription box prominently located on the right side of the new kbmchealth.com. Ken Brown I think it looks so nice. You did an excellent job. Eric Rieger I did not do that. That was was the help of Stephen and people that understand how to build websites. So our bad website that we had before was me. And we moved over to a real one. Ken Brown Which is an awesome website for CRNA.Eric Rieger Yeah, that's exactly right. So if you want me to build a home, and you want to say I got a home built by a CRNA, and it may or may not have a door that closes, you should totally ask me to do it. But otherwise, no, Stephen and Drew and Mark did a great job I think putting together a pretty cool, easy to understand website. And just so that everyone knows there are new pieces going to be added as time goes along. We have a large repository of CBD information that's going to be added to the website. We've got ways for people to access videos where they can get educated on on things that may not have anything to do specifically with polyphenols or CBD we there's a lot of things they're going to add to the site. They'll be easy to find. Ken Brown This is so exciting because we've done so much background work of trying to set the store up trying to do different things now we can start to really interact with everybody. We want this to be a community. One of the things that can lead to disease is the feeling of loneliness. So if you're feeling lonely might as well join this community, hit us up, say, Hey, I read this article on this, can you look into it? And that's kind of what I want this podcast to grow into where we can sort of play. We can vet stuff, we can get new stuff out there, we can get people communicating. Look at all our patients that show up and they're like hey I watch your show. I would like to come on and talk about this like, yeah,Eric Rieger Yeah, happens happens more often than I would have expected, especially as early as we've been doing this.Ken Brown Oh, you wanna know. Another way we're going to get a lot more people here...our friend Dan Clark. brain.fm. Yes. So we we have this we have been fortunate enough to meet this incredibly intelligent CEO named Dan Clark, who was named I think 30 under 30 in Forbes. Yeah, well, they have a app that when you put headphones on, does something called neural phase locking neural phase locking, which some people confuse it with binaural beats like I did, but what it does It stimulates various areas of your brain so you can calm down or wake up. I actually when I actually use it to go to sleep, and I use it to wake up, and that's when you and I were talking, and we're going to start out seeing if this can help calm down my patients before colonoscopy, and help them wake up quicker. So if you're listening to this, and you need a colonoscopy, you can be part of something really cool. No, it's it's just headphones and music. So it's not dangerous, it's going to be really cool. And we're going to get some really neat data out of this. When we tried it on our first eight patients they all loved it. Eric Rieger They all loved it. There was it wasn't just an absence of complaints. It was really just robust compliments and thanks so much for letting me be a part of it. Ken Brown Can you imagine if you're sitting in the waiting room of a of a dentist's office or something that you really don't like or your gynecologist or whatever it is, I'm using doctors but this could be the IRS or whatever, putting some headphones on and taking yourself down and calming from the brain which will then tell the cortisol to decrease and everything will calm down. It will be all good. That's it. That's a whole new level of science, which I'm super excited about. Because there's really no side effects. It's music. Eric Rieger It's just music. And it's actually really, really cool. Ken Brown Based on science. Music based on science with functional MRIs and everything. They've got some studies where they showed a the relaxation scores of people that have listened to the most "relaxing" music are having the most relaxing and then the control was Coldplay, which I thought was really funny in their study, and then they had them listen to brain.fm and unequivocably all the people that had brain FM felt much more relaxed. So there is some really cool science to this. Now we're just going to add some objective data. And maybe we'll be able to get some patients that absolutely love it. This is this could be the future of what we're going to do. You use less medicines. My patients are happier and it's a win win win for everybody.Eric Rieger Anything that we can do to make the experience of going in for an elective procedure or any really any stressful situation, but if we know that we can help people feel better, why not try it and it's just sound so we know we're not causing pain or harm.Ken Brown So I'm going to like I'm trying to get my kids with this where if they are getting ready to like so my kids play tennis, which is where the family is right now they're in Florida winter nationals. In fact, Lucas i think is in the throes of a match right now he's still in it. They've been there since last Thursday. Eric Rieger Right on. Ken Brown Yeah, they've been there for four weeks. So the you know, you go home when you lose and he did he's out of the main draw. He'd lost in a really tough third set battle but mentally came back and has won three more matches which is which I think is the coolest thing when you lose to not just let your give up right there but and so he uses he actually uses my account at brainfm. Don't tell Dan that we're sharing an account. He uses my account for whenever he studies and so he likes it so yeah, I think that that's it I think it's super exciting. So what's going on? Oh, how were your holidays? Eric Rieger Holidays were great. We had we had family in town for for Christmas to come visit we cooked steaks we chilled out we I mean we saw everyone we saw everyone on my side of the family, on Marie's side of the family it was it was a lot of fun. The boys the last obviously just like Lucas and Carla, they had basketball tournaments. Mac had a great tournament for the junior varsity. They really played up for the JV. They played bigger schools, they ended up closing out their last game they won by 30. Ken Brown Won by 30?Eric Rieger Yea. So they were really happy with being able to close up the tournament with that. Mac and his whole team. I mean, they're really preparing to next year they'll all be on varsity. So he he and his brother get along great. He just wants to be able to contribute just like his older brother did, who actually competed in one of the nation's longest I think the top four or top five longest running high school basketball tournaments and that's the Whataburger tournament and Gage's Decatur Eagles, second year in a row, won the whole tournament. And Gage was named all tournament. Ken Brown Woo, woo. Go Gage!Eric Rieger Yea. He played. He played really well. Super proud of both of the boys. It's I mean, it's just It's fortunate to have to have these opportunities with your kids. I wasn't an athlete like that. So it's just so much fun to watch them work so hard and achieve and they do it as a team for them.Ken Brown You're not concerned that gage is going to try to be like Al Bundy sitting on a couch talking about his 2019 glory year of basketball when he's like 45. Eric Rieger We talked about it every night. To make sure he doesn't do it. Ken Brown Don't be Al Bundy. Eric Rieger Yeah, we use the brain FM anti Bundy music track.Ken Brown Yea, we have to make sure that he continues to succeed in other areas. He committed to Texas Tech so that's a good start. Eric Rieger Yeah, he's gonna play there...intramural, but he'll play there. Ken Brown There we go. Eric Rieger There we go. Well, let's let's get into it. SoKen Brown Yeah, well, I got one other thing that's super cool over the holidays. Oh, by the way, I'm one and a half days into my five day fast. I'm starting the year with a fast. Eric Rieger Nice. Good for you. Ken Brown Yeah, so we're that's where I'm at to get my get my water tea broth kind of thing. Just going to try and do that to liquid fast. So we'll see how that goes. Speaking of fasting, got a really cool contact. Do you remember Melanie Avalon podcasts intermittent fasting podcastEric Rieger I definitely remember MelanieKen Brown Super cool person very smart you know crushes it on the on the whole podcast scene. Well, she contacted me and she has a new app out. Oh no. Yeah, really cool an app called the food sense guide. I need a favor from you. Eric Rieger Okay. Ken Brown It's a searchable comprehensive guide to over 300 plus foods for general levels of different things like the amines, fodmaps glutamates, gluten, histamine, lectins, oxalates, salicylates, sulfites, and so on. If you don't know what any of those are, it's because you're very fortunate, and you don't have to worry about what you eat. But that world is my patients. They come in and we talk about diet. So now this is gonna be really cool. I'll be able to help Melanie out, put my patients on it. Unfortunately, it's not on Android yet. And I got a Google Pixel. So I'm going to have you download it and then we're going to play with it and then we're going to post a review for her. And if anybody else wants to download that, it's the what did I say it was it's the food sense guide on the iTunes it's for iPhones only now. So take a look at it if you've got food sensitivity or anything like that, or your doctor said, try fodmap or you just want to try some different things. It's a great start.Eric Rieger Food sense guide. Sense?Ken Brown Yeah, food sense guide.Eric Rieger Food sense guide. Yeah, download that from Melanie. She runs a great podcast, actually two different podcasts. And she does an awesome job of keeping her audience up to date with the latest information. So I'd feel completely comfortable in going ahead and recommending it as we try it.Ken Brown Absolutely. And we'll get to we'll eventually get a code for everybody that maybe we can get a code so that they can get a little discount or something. Who knows. Let's start the new year out. I want to ask you a question. Eric Rieger I'm ready. Ken Brown I want you to be honest. Eric Rieger Okay. Ken Brown Do you use your phone when you're in the bathroom? Much like our mascot here? Gutsy. Do you use your phone like him when you're in the bathroom? Eric Rieger As much as I want to say no, that's not true.Ken Brown Well, as it turns out, you are not alone. Eric Rieger I didn't think it was. Ken Brown Different studies have shown that up to 75% of Americans do this. So, next time you're scrolling through on your Instagram, and you see that sexy Instagram model picture, there's a good chance she's sitting on the toilet while doing that, while she's posting. Think about that for a moment. Eric Rieger That's where the work that's where the work is done. Ken Brown That's where that's what they're saying is that many a lot of the Instagram posts and everything are probably done when people have a little alone time when they've they've taken their photo shoots and then it's time to upload it. Eric Rieger It's funny, they say probably with a with the GPS stuff that you give up just by using those apps, they probably know that that's where you Ken Brown Well, they certainly know for sure. On 20% of the people to do it because 20% of Americans have admitted to dropping their phone in the toilet. Eric Rieger Oh, and I've not done that. Ken Brown 20%Eric Rieger Yeah, I'm in the other four out of five. I have not done that. And I don't know that I would reach in to grab it. That just may be it.Ken Brown I think that's why I think that's why the new iPhone is bragging so much about being waterproof. That's what that's what the commercial should be. It should be an Instagram model that drops it in the toilet. She's like, eh, grabs it and pulls it up, keeps going.Eric Rieger Now I don't think it should be that they may make one like that.Ken Brown Now, wait a minute. As a gastroenterologist, I encourage everyone, to when you sit on the toilet, I want you to snap, tweet, Facebook, Insta, play Words with Friends or whatever it is that people do buy Atrantil online through, you know, through the website, and you can do any of that. Because when you sit on that toilet for a long time, you're going to create hemorrhoids. I love hemorrhoids. I love treating hemorrhoids. So I encourage everyone to go ahead and do that. But almost everyone, almost, I'm not gonna encourage my employees to do it.Eric Rieger No No you probably wouldn't, because that would run up a bill on the opposite end trying to care for it.Unknown Speaker Well, it would also run up the It would also decrease the productivity.Eric Rieger Yeah, probably soKen Brown And leave it up to the Brits to figure this part out. Eric Rieger What's that?Ken Brown Well, this is all leading up to a study, I was actually going somewhere with all this. I know you're looking at me like why are you focusing on the phone in the toilet so much? Eric Rieger Well, I mean, I was but I was I was genuinely interested.Ken Brown So let me ask you, in the UK, it's estimated that the lack of productivity due to extended toilet breaks, is costing the United Kingdom $7.5 billion dollars a year. Eric Rieger 7.5 billion? Ken Brown Yeah. So you're the chancellor, Emperor of England. Is that Emperor now? or What is it? It's a...Eric Rieger Guardian? Ken Brown Guardian?Eric Rieger Yeah.Ken Brown Okay. Eric Rieger Something like that.Ken Brown That's beacuase I'm wearing my guardians of the galaxy shirt. Eric Rieger That's exactly where I got that from.Ken Brown All right. I want to know, Eric Rieger. What would you do if you were president of united states and you say, we can We can improve our our overall bottom line by getting people to get off their phones while they're in the bathroom. Eric Rieger What would I do about it? Oh my goodness I if I honestly I just don't even have a smart alec answer. Scramblers? Not really sure.Ken Brown Well, I was thinking about that also cuz I'm like, where's where's this article going? Where they're talking about people $7.5 billion being lost like every time you know, you go to the bathroom, you just go to Cha-Ching. Ken Brown Seems like a lot seems like overkill and it seems like thers... So as it turns out, there was a who is now CEO of a company, a British designer was waiting to use the restroom at a truck stop while waiting for stalls to open up. And what he noticed is that all these guys were coming out holding their phones, and he was getting super annoyed because he had to use the bathroom and everything was taking a long time. Yeah. So it occurred to him that this is probably going on at work. So he designed a toilet that slants eight to 13 degrees down. Eric Rieger It seems like a lot though.Eric Rieger You know what I saw this. Ken Brown You did? Eric Rieger I saw the design, it looks like it was very uncomfortable to sit there for a very long time. is that right? Ken Brown They purposely built a toilet so it's uncomfortable to sit in. Actually, what it does is and you can choose so if you're like, if you're a nice boss, you just do eight degrees, you do 13 degrees and what it does, it makes you kind of stand up so your quads burn. So you have all these now you can start seeing all kinds of Instagram models with giant quads and just big legs. It's gonna move from the Kardashian bottom to the to the Insta thighs that look like a good leg press. 1000 pounds, but so it's making them uncomfortable. What's your thoughts on that?Eric Rieger Man, I don't know. It It's interesting, I don't think that you can. I think what we, where we are right now is we've just identified a in terms of the employer. A time waste is what they feel like. But I feel like that people have been finding ways to waste time since the dawn of time. I don't know that you're really gonna curve anything. In fact, I would say that there are probably some who's still trying to remain productive by answering email. I mean, I don't know what they're calculating. There's 7.5 billion on that of those who just can answer text or email. I'm just throwing that out there. Ken Brown Oh, yeah. That wasn't taking into account maybe it's more productive for some people. Eric Rieger Yeah. I mean, it probably really could be better. Ken Brown But you're saying like since the dawn of time, what were those people that would send Telegraph's Do you think the guy would like take it into the bathroom and go?Eric Rieger Yeah, you got an extension here. Little extension cord is one in there. Ken Brown And it's been going on since the dawn of time. Eric Rieger Beedle E Beat where ever he was to do that. Is that the correct word for it? From Western Union? Ken Brown Yeah, exactly. It's the Western Union person I'm thinking. That's exactlyEric Rieger I don't know. I mean, a slanted toilet though I mean, for those who don't waste time in the in the bathroom, it seems like a disservice to them to have to be on an uncomfortable toilet.Ken Brown So it got me thinking a little bit. So I just found the article kind of funny. And I thought it'd be interesting to talk about here. But now let's science it up a little bit. So the reality is, what they're doing is they're actually, so there is something called the optimal angle of defication Eric Rieger Wouldn't that be undoing that? Ken Brown It's undoing it. So it's going to be counterproductive. Yes, they might be off their phones, but they're not going to have an effective bowel movement. Eric Rieger Sounds to me like they won't evacuate as well. Ken Brown And it'll take them longer to evacuate leading... Ken Brown Multiple trips, leading to more Hemorrhoids and things like that. So the whole concept of Oh, I'm just going to make this uncomfortable, is going to completely backfire. In fact, in 2011, I did a whole blog on this. If you go to Kenneth Brown, MD. com, I did a blog on the angle of defication. And what they did is some Japanese scientists, they took people and they well, it's unfortunate, but they took medical students, and they actually put radio paste in their bottoms, so they can watch them deficate. And then they had them do this multiple times with various angles. So they did it was like an engineering type thing. You can see the perfect angle. And the reason why we need a certain angle is that we have muscles down there, one of them called the puborectalis muscle. And when it doesn't completely relax, well, you can end up having a very ineffective bowel movement. So when I talk to my patients, I say, do you get the urge to go to the restroom? They say yes. When you go to the restroom, do you feel that you are fully evacuated? They're like, No, I have to strain a lot. Are they constipated? And by constipation meaning are you just not getting the urge but when you have the urge, you can't get it out. In my mind. That's not constipation. That is an evacuation issue that is pelvic floor. Dis synergy is what the actual medical term is. Wow. So there's little tricks to fix that. And it's the exact opposite of what this toilet is. The first trick is you actually get your knees above your hips. That's how squatty pottys making a living they're getting people to do that. Eric Rieger Multiple trips. Eric Rieger That'swhat they do. Ken Brown And then if you lean slightly forward, what they figured out is you get that muscle to kind of come out of the way. One of the things is, I started really thinking about this the reason why I wrote the blogs because one of my patients said, Hey, whenever I go camping, I don't ever feel constipated. Why is that? I'm like, do you dig a hole in the ground? She goes, Yeah, yeah, cuz like, Okay, she goes camping a lot, she's like, and you dig a hole in the ground, you're squatting so we're one of the few countries well now England for sure. But we're one of the few countries Well, I just take it back. Western countries use toilets, but most of the countries that don't use aboveground toilets do not have hemorrhoid or constipation issues. Eric Rieger No they're in optimal defication pose. Ken Brown They're, an optimal defication pose so I just thought it was kind of interesting that somebody would go around and and purposely build a toilet. And I started thinking of all my patients that have like serious issues, Chrone's, colitis, irritable bowel, bacterial. It's it was described by a couple people on Twitter as a dystonia, dystonia era in the bathroom. Eric Rieger Yeah. I mean, somebody's always gonna go a little too far. Yeah. I mean, so what were alternatives be, I've noticed that there are certain bathrooms that maybe only have like one or two stalls, and oftentimes because they aren't frequented, they'll have the motion detector. And I've heard stories that people saying that they they knew they were in there too long because the motion detector timed out and they were in there in the light went off. You know, so, I mean, I think there are other there are other ways that won't actually hamper your natural ability to use the bathroom, but maybe we'll get your attention that you've been there too long, whether it be lights off, you know, clicking off or maybe a bell with a lock on the stall doors been engaged for too long or who knows? Ken Brown You know what? Something that might work. Also, did you see that YouTube video of Mark Rober with the exploding glitter bomb for the porch porch pirates?Eric Rieger Oh yeah I did it the the parcel box it just basically shredded and sprayedKen Brown And sprays glitter.Eric Rieger Yeah. Ken Brown For people that that actually steal it. It's I mean, he's gotten tons of notoriety. Yes, he's been on Jimmy Kimmel a bunch of other things, just little mini little things and have a timer that some people walked out they were glitter on their face. Ahh a little too long huh? It's the Mark Rober bathroom bathroom optimizer?Eric Rieger Yeah. I mean, it seems. Again, it seems aggressive for somebody who may actually have a legitimate issue but I mean, you probably could be a little bit more inventive than creating a disadvantage for everyone that needs to use your your toilet. Ken Brown Yeah, I thought that was kind of an interesting way to start a year. You show up to your job. And you're like has anyone seen those toilets yet?Eric Rieger Well, when I saw that, I mean, I almost think it was a YouTube TV news story or something like that. Because when regardless, it doesn't matter. I saw over the holiday, but I thought it was a joke. So I didn't think it was real. I saw better I saw them showing the plane and then the the angle down of the toilet drawn there but I had no idea that was a serious solution proposed by somebody I thought it was other than being silly. Yeah, so it is pretty silly anywayKen Brown Lead line them so you can't get Wi Fi or phone signal.Eric Rieger Yeah I mean that that would probably be the quickest expediter and would filter the right people out right?Ken Brown Oh, they'll die from lead poisoning eventually. That will filter them.Eric Rieger Yeah, but I mean you would definitely filter the right people out because you wouldn't have you or at least have a scrambler because you could the people who are legitimately need to be in it for a long time are going to be there no matter what. And the people that were wanting to play on the phone couldn't access their phone.Ken Brown Yeah, but in in all seriousness, it is. It is a really big deal in my field hemorrhoids rectal bleeding if you do this, go to YouTube and take a look at our rectal bleeding video so that you're not too concerned. And then we can if you're local, make an appointment to fix those hemorrhoidsEric Rieger We got a cool e book coming out here pretty soon they'll be able to make public yeah That'll be not only will it have a couple of suggestions for solutions that you can participate in, but pretty soon it will have more than one option and I can't really talk about it today, but I'm excited about that.Ken Brown Awesome. What else you got on your mind?Eric Rieger I really don't. I mean, we're starting off a new year, new year for everyone and it's 2020 I think it's got a lot of cool plays on on words. It was pointed out to me earlier this morning that just as a quick PSA, if you're writing a check, or something that requires the date for you to have written in normally in the past, you may have written October 3 2019 is /19. You probably want to go ahead and write out the 2020. Okay, somebody else could miss date for whatever advantage that they may have. If you happen to run a 20 somebody else could follow in and put a one eight or 190 Yes, a trailer on there and possibly do something to a document just a little anectdotal has nothing to do it today. But then again, it does. So maybe just to protect yourself right out 2020 I don't know. I have no idea there's any legitimacy to that or not, but it's interesting.Ken Brown So we that is Eric's public service announcement of the day. I wish I had one of those little shooting star things that you know Ken Brown Yeah. The more you know.Eric Rieger The more you know, Ken Brown Eric's The more you know, segmentEric Rieger Maybe Paul will give us a little wind chime or something right there.Ken Brown You want to get nerdy for a moment? Eric Rieger Let's do it. Ken Brown Alright, so there's a there's been a lot going on in the news. A lot of stuff has been published. We haven't a chance to talk about. Something I came across that is a passion of mine, you know that one of my big things. I there are epidemics going on right now. And we know that autism is an epidemic,we know that autoimmune is increasing. Well, the other one that I'm you know, really want to fix because I feel like you spent a whole life loving, hurting, living seeing things collecting memories, and then dementia and Alzheimer's sets it. To me, that's one of the most horrific diseases that are going on. And it's exponentially increasing. And there's a lot of confusion as to or there's a lot of reasons as to why. But a recent study just came out of the University of Berkeley, it was in December 2019. It came on out of the Journal of science and translational medicine. What they did is they looked at essentially senile mice, and they're trying to figure out what made some of these mice and they were given them different markers to see if they could create neuro inflammation or brain inflammation. Well, as it turns out, even if they looked as the mice aged, almost all of them started having decreased cognition, especially fed on the typical human or Western diet. Yeah, the American diet. Eric Rieger I think I know where we're going. Ken Brown So very Interesting what they did is they talked about this in a very unique way. I've never heard of scientists going down this path. And this is University of Berkeley. This is you know, these are these are legit people that are finding something they had their aha moment that you and I've talked about a bunch. What they found is we used to think or the trend right now not we used to because the current trend is is that the aged brain ages in the same way that everything else does. You have neuro degeneration, you have less nerve cells, you've got decreased capacity to learn more and all these other things. There are some people that believe it's micro infarction, there are some people that believe that it's amyloid plaques, but either way, your nerve function is decreasing. So age involves loss of function and dead cells, generally speaking, which is how we age. But there's new data to tell a totally different story about why the aged brain is not functioning well. It is because of the fog of inflammatory load. Eric Rieger Make sense. Ken Brown And my we always talk about this patients that come in with irritable bowel bacterial overgrowth. They're like, Man, I'm not right, I'm in a brain fog. Now we realize that that brain fog could potentially be an inflammatory load in this mouse model, they're showing that. So when you remove that inflammatory fog, they call it the inflammatory fog. When you remove that inflammatory process within days, the brain starts acting like a young brain.Eric Rieger That's impressive that they've been able to kind of morally morally more establish this connection because it wasn't that long ago that we were before we even started the podcast having a discussion that if you have a leaky gut, more or less, it's probably correlating with a leaky brain, right? So if you have permeability issues in your gut, chances are it's a systemic issue, and it's occurring, what they call the blood brain barrier, which protects your brainKen Brown 100% I think it is interesting you brought up morally because unlike the gavage study that we talked about a few weeks ago about the CBD, just gavaging tube down the mouse and just pouring buckets of it. These guys are actually waking or like helping these mice out there like, hey, look, you got a young brain now. So, more and more research is showing that with age, the filtration system, that's that blood brain barrier prevents molecules or infectious organisms from the blood leaking into the brain. This is the blood brain barrier, like I was saying, over time. In fact, they were showing that after the age of 70, it becomes more and more leaky, letting in chemicals that cause inflammation and a cascade, which ultimately creates this brain fog, which ultimately does lead to cell death. So after age 70, nearly 60% of adults have leaky brain barriers. I'll say that again. After age 70. Nearly 60% of adults have a leaky blood brain barrier and this is according to some really cool things. This is a MRI studies where they're looking at this, this is functional MRI studies. So it isn't just, you know, we can't really get in there and biopsy the brain and do these different things. So the inflammatory fog induced by leaky blood brain barrier alters the mouse's normal rhythms. And in these mice, this is fascinating. And I'll say it again, because my patients come in and they're like, I'm not right. I just feel like I'm just not firing on all cylinders. They showed in these mice, the very first signs of this are micro seizure like events, little tiny little seizures. It's not a total, it's not a total seizure, where your body does just in these little areas, like momentary lapses in the normal rhythm within the hippocampus. Eric Rieger Interesting. Ken Brown Alright, so now think about this. We talked early on about the neural phase programming, or neural phase locking. So the brain is an electrical impulse, everything comes down to this. This study shows that when you have leaky brain caused most likely by leaky gut, that you're going to have an electrical impedance problem, which they're detecting through eeg, or different processes as micro seizures. So everything comes down to electricity in the brain. So it's it's really interesting that I wonder if the science and neural phase locking could get to the point where you could counteract some of the seizures that are going on. That's a whole separate discussion, but it just gets you thinking. It's like hmm.Eric Rieger It does get you thinking, but it also makes me wonder, a couple of different questions. One would, how would a lay person be able to identify they had a micro seizure? Two would be how do I control inflammation because it sounds to me like concentrated inflammation is putting me a risk of developing these issues are being a part of the 70% over 70 having these problems, right. And then three, the people that don't or the mice that didn't show that they had these breakdowns in their blood brain barrier were they without significant inflammation universally. So were they comparing these two and showing that we had people or mice that didn't have inflammation and they didn't exhibit these problems, see what I'm saying? Ken Brown Oh, yeah. Eric Rieger So or and then I guess the fourth would be would that number be as high in a country that didn't consume a traditional Western diet every day? And maybe had more polyphenols or Mediterranean style diet?Ken Brown Very interesting fact. I will just look at this not to get off topic. I'm going to finish this. Yeah. And then we're going to talk about that because I watched a Netflix thing and I want to just briefly hit on because i'm really confused. Eric Rieger Was it the office? No? Okay.Ken Brown When you have this these little micro seizures, what they found in this mice is it produced some of the same symptoms seen in diseases like Alzheimer's and they were able to show with EEG's, really sensitive EEG's. That's what neurologists will put the, all those little wires attached to a head. And they can see if somebody's seizing, they could see this and really tiny little levels, they revealed very similar wave disruption, or they were showing a paroxysmal slow wave event. Literally, the inflammation was slowing your brainwaves down. Yeah, all my patients that go, I'm just not on, something's off. Their brain is being slowed. It's like trying to go through molasses as it's trying to conduct a current. So in a normal human with epilepsy with cognitive dysfunction, they can actually show that there's mild cognitive impairment. So even if you're not having the seizures, they can actually show that you could probably function at a higher level if you can get that fixed. So what's really cool about this paper is you were saying how do I know that this is happening? Right? This is the first time ever these The reason why I think this is a seminal article is because the papers give Doctors, two biomarkers. These two biomarkers are leaky barriers detectable by MRI and abnormal brain rhythm detectable by eeg, what they've been able to show is even in humans, young brain, old brain, they can show the leakiness of it or the permeability. And then they can show where that's happening, that there's increased micro seizure activity going on. really fascinating because what this allows it to do is it is a tool to say, Oh, I mean, that would be awesome. If I could, my patients were to come in, and I'm like, Look, we're trying to figure out if you've got leaky gut due to bacterial overgrowth, or whatever. And remember, nobody's been saying leaky. I mean, I've been saying leaky for five years, and people were laughing at me and now you've got people like at the Mayo saying leaky gut, now you've gotten these guys saying leaky brain. I mean, clearly, we're just defining something that inflammation is bad if you can keep inflammation out of your brain in any way possible. And that includes trauma and that includes drugs, alcohol, all that stuff, you're just going to be better offEric Rieger Hundred percent I can remember we we tried to find five years ago if if leaky gut was anything that anybody was searching for. And at that time, the answer was no. And nowit's everywhere. Yeah, so it's applicable. Ken Brown Yeah. And so what's what's really cool is, you know, you can imagine if I could take these, I could take a patient and say, Oh, you're you're having leaky brain, much like checking a low density lipoprotein or, and all the other cholesterol markers that we do to try and predict if you're gonna have a heart attack, if I can get in there and go, okay, you're having some leaky brain and some inflammatory process going on in your in in your brain. You're 40 years old. We need to stop this. And we now have a marker where we can do this through change in diet, protecting your gut, taking the polyphenols, things like that. Then we can show that that's going to decrease and then you do in a preventative thing for dimentia. Yeah, super cool. Now these guys are going to take it one step further. And they're not, I don't blame them. But they're, they've come together and raise some money and they're going to try and develop a drug to seal the blood brain barrier. Eric Rieger Okay? Ken Brown Make sense? I mean, you figured that out, they want to slow and reverse this, they have started this company to develop a drug to heal the blood brain barrier for clinical treatment. Now, that being said, I'm a little bit biased, because I believe that the inflammation doesn't start in the brain it can't. It's not like the something has to be out of the brain. Think about this for a moment. And they didn't get into this at all. They didn't talk gut at all. To cross the blood brain barrier, you must be coming from outside of the brain. So the blood something in the blood is inflammatory goes into your brain, and your brain reacts to it and then you have the fog or the heaviness of inflammation.Eric Rieger This is not an just just for the listeners. The blood brain barrier itself is not a new concept we have drugs that we know that do and do not cross the blood brain barrier that apply to all kinds of different diseases or anesthesia that we use with patients.Ken Brown Yeah, as an anesthesia provider. This is this is your world. Because your job is to get those drugs past that so that you can calm the brain down.Eric Rieger Yeah, I mean, there there are some Anticholinergics that we know that do and technically do not cross the blood brain barrier. But every now and then, and then aged patients, some of those that we felt like shouldn't cross the blood, the blood brain barrier I can, I can still remember looking back and it's going well, we didn't think we would get that response with this. But we also weren't talking about leaky brain a decade ago. We weren't talking in those terms. And it's kind of exciting because I think that we're rounding a corner really understanding the systemic effect of bad gut health and how it actually affects the entire body. Ken Brown What'sso one of the one of the problems I run into in traditional medicine is when I talk to my colleagues, I'll be like, Oh, I haven't seen a study on that. You want some water? Yeah. They'll say, Well, I haven't seen, I haven't seen a clinical trial on this. And the, the only way that clinical trials can get done in these kind of things, is to go through either a huge NIH grant to have a big pharmaceutical company pay for something like this. But what you need to do is look at the objective data, like this mouse study here. We're not talking whether a drug can do stuff, what we're showing is that there is a comparative analysis between a young mouse and a young human, and you do this functional MRI study, and an old mouse and an old human and you show the intestinal permeability, or I'm sure you show the blood brain permeability, and you can show that there's a cognitive decline. So we can agree if we can agree that and if I'm talking to even a skeptic, they'll be like I don't believe in that the blood right, but we know you just said the blood brain barrier is a selective brain barrier. Yep. The gut blood barrier. So the gut barrier, the tight junctions is a select permeable barrier permeable, its job is to let certain things in, keep certain things out. When you disrupt this, it can allow too many things in. So let's start with the gut. And let's just assume that you have something happened infection, drugs, bacterial overgrowth, and it causes an inflammatory response. Different things like zonulin show up which lead to some intestinal permeability, then that turns on your inflammatory cascade, and now you've got these little inflammatory markers floating around the blood. These guys believe that they can develop a drug that will actually block TNF beta. I think? Because that's what they're going to go after, so they're gonna, they're gonna try and chase the inflammation in the brain. I'm opposite. Eric Rieger Let's just stop inflammation. Ken Brown Let's just stop the inflammation. So there was that one study, I think you're making small reference to where they actually looked. And they took human intestinal tissue and then they took a blood brain barrier tissue, so cadaver tissue, and they did an impedance study where they soak the tissue in some inflammatory they started. And what they did is they took the normal tissue, and then they did these different size molecules. So one way to determine if somebody is having some leaky gut is that let's assume that our dung beetle here is a is a certain, whatever kill adult I don't even know what size there but it's like the really tiny. And so they use these molecules where they can sit there and show and what they'll do is they'll soak the tissue and then the dung beetle can't get through and so just moves on. Then they soaked the tissue in inflammatory typical inflammatory cytokines, meaning the stuff that you're going to produce with all disease, TNF alpha, interleukin beta, like all these different CRP, CRP, you know, stuff like that, so they did it specifically. And then what they showed is the dung beetle went straight through, so then they found the dung beetle on the other side. He was going around, they're like, Uh Oh, so then they did the exact same thing with the with the blood brain barrier. And the first time they went through the blood brain barrier, blocked it, they put it in the exact same inflammatory cytokines. And it just opened right up. And then he's had a little party.Eric Rieger Well the cells, maybe in two different locations, but they are very similar both in structure and function in the way that they protect what they're there to protect. So it's not really that surprising. And you don't have to think that hard to understand that the blood is simply just a vehicle to spread markers all over the body in different parts of your body going to respond in different ways. There is no, to my knowledge, there is no set assignment for a marker to only go in one direction down one vessel to reach one destination. It just goes everywhere until it lands where it's gonna land. And so that's kind of how the brain gets affected. It's your gut is sick. Yeah, I mean, if you're gut is sick, chances are other parts of your body is going to be sick as well.Ken Brown It's so then this kind of gets into this part. So now we're having these discussions. Finally we're finally seeing in the literature discussion about leaky gut leaky brain. But we're what we're talking about is these things cause chronic condition. And it seems to be getting worse. So I made either the mistake or a brilliant move. I think a lot of people have talked about game changers. Yeah, Game Changers the end. So I took it a step further because I was on I was on hospital this whole week. My family's out of town. So when I had a moment, I was watching some Netflix, sitting on the toilet, you know,Eric Rieger texting? Ken Brown Texting. No. I watched what the health and I think you had told me about this years ago. Eric Rieger That one's a real kick in the gut man Ken Brown That one. Oh, my goodness, that one's...Eric Rieger That if you don't like game changers don't watch that one.Ken Brown Yeah, that's worse. That one's next level. And the problem is, is that it's, there's just an I get that all of a sudden you guys I youtubed afterwards and rebuttal after rebuttal and all this other stuff, but you know some of the stuff you're like, Oh, no. What if I love meat!Eric Rieger Well, I will at least say this. I think that the game changers for the most part, the producers, and the writers probably believe a lot of what they say. I felt like what the health was just engineered to mask. I mean, I felt like they were they were bad da withholding evidence through a lot of it. It just did not. It did not pass the smell test. Ken Brown I could see how it could it could go around. So I had my annual doctor appointment this morning. And so it's with its with Kevin Wilson at smart wellness now, and he's a he's a functional medicine practitioner. And so we were I was asking him about this. We're going over my labs and everything and he is a strong, I guess, a paleo style. You know, autoimmune paleo style lifestyle here kind of thing. He looks great and he's got no fat on him his and so we talked about his blood work. You know his typical diet is six eggs with ham and cheese in the morning and then some leafy greens with some grass fed meat and then have a little bit of carbs like that sweet potato with a smaller meal and we're talking about his labs and his cholesterol is perfect and his you know, insulin levels are perfect his hemoglobin A1-C. And then so we started talking about different things. I tried the whole plant based diet but I think I did it wrong. And I went get all the the fake packaged sausage and chicken and everything and I got really inflamed. I don't think my body went with that. Then we started talking about differences in his patients and what he's seen and so he had two patients that went on the carnivore diet and one labs completely improved and the other one didn't change at all. And so you just start looking at these different these different movies and stuff and you go Okay, what is let's take a big step back, getting away from the whole thing of plant based slash veganism or carnivores slash paleo, you know, those are I guess, those are the The the diets that people will really be kind of passionate about because they're kind of on the extremes over here and go, okay, is it possible that we're all genetically meant to have a slightly different diet? Is it possible that you know, there's a lot of different so like in my blood work, I'm very surprised I my LDL has crept up a little bit. Fortunately, my HDL is still real high. Yeah, my inflammatory markers are nothing. And so we're trying to figure out well, why did your cholesterol go up a little bit? Well, I do play around with my diet a lot. I'll go into extreme. And I think it kind of throws my body for a little bit of a loop but then it got me thinking, I started looking at different countries with the highest incidence of coronary vascular disease and, and you look and it's, it's Russia, Germany, it's the US and then you come down and then there's Spain, Italy, Japan are that are the healthiest right now is that crops is that lifestyle is that the polyphenol content, you know, I always think that it's diets really based on the polyphenol content and then I watched Patriot Act patriot act with oh we're gonna have to look that up Hassan the comedian. Eric Rieger Oh yeah the show? Ken Brown The show. Yeah so I think the his last show of the of the year was looking at how America is making other countries fat and it really targeted one particular company, really Coca Cola. High fructose corn syrup when they have shown that high fructose corn syrup is brought in and some of these countries like China, Mexico I'm trying to think of all these other countries but just India, country after country that starts getting exposed to this then that's like the window to come in. And then it ends up being that you have these fast food places and stuff like that. And without a doubt everyone is definitely becoming more obese. So is it this all started. Oh, that's all I did not know this. It's gonna be blamed on Richard Nixon. As it turns out, yeah. When the economy dropped and he goes into explain it, obviously he's a super smart guy. Yeah. And he's funny, but he's really make sense. Yeah, he was describing that Richard Nixon did that for a bunch of different reasons. And Hassan actually says that he goes, there's a bunch of reasons here for like, economics. I won't get into them if you want to pause it right now and write these down. But it basically goes into why richard nixon did some sort of farming subsidy to allow the increased growth of corn.Eric Rieger Okay, yeah.Ken Brown And so it was some sort of subsidies to keep the economy up and all this other stuff. And so then they had this excess of corn that then became high fructose corn syrup. It's then as in everything, Eric Rieger Yeah, it is. Ken Brown That's where you start. That's I apologize earlier, when I said that the track athletes take high fructose corn syrup. They take straight fructose, which is the sugar in fruits. But once you convert corn to high fructose corn syrup, that may be the culprit. That's what's in all the sodas. That's what's in everything. You just got me thinking that if we're over here saying our plant based it's carnivore diet. I don't know. But I do know that if you're opening a package, probably like what happened to me, when I tried to do my whole vegan diet for a week where I was trying to subset I was trying to substitute every meat that I would normally have with some sort of meat substitute. I got super inflamed. Yeah, I don't think it was toxins leaving my body,Eric Rieger Probably not in every instance. But it seems like if things are compounded to withstand or extend shelf life, more than likely, it's probably not the best way to consume whatever it is you're eating.Ken Brown So I'll give everybody an update. What I'm gonna do is I'm gonna change my diet a little bit. I'm going to be actually I've, I just, you know, just dabble in different diets and have, you know, fun with it and go on the extreme and whatever. And so, Kevin and I talked, it's like, okay, we're gonna, we're gonna put you on an actual regimen. You're actually going to be a patient now and you're going to like, actually do what I say. And so I had to laugh. I'm like, okay, no, I don't really do that. We're gonna see what happens. I mean, it's the good news. You know, he's got he's got a lot of his patients where he wants to get their hemoglobin a one see below four.He doesn't play around with that 55-56-57 range that a lot of people are happy to be in. He wants him below four. And not really even looking at body fat, stuff like that, because then what he's looking at is inflammatory markers, sed rate CRP, different things like that. And what is really kind of interesting is that my cholesterol went up and we were trying to figure it out. And what I had been doing, which is a little bit of a curveball is you know, I do intermittent fasting. What could be and then we looked at my genetic profile, I'm a cholesterol hyper absorber genetically. So, it I may be the small subset of people that should probably have just strict three meals so that my body isn't absorbing. Because, you know, because that first meal I'll just rawr, yeah, sure. You know, and just ravenous don't know, it's just it's another little caveat. It just gets, it gets back to the whole thing that maybe there isn't one thing for everybody and everybody has to take a step back and maybe go see a really smart guy like that. That looks at your blood work, looked at your genetics and says, Okay, this may be better for you.Eric Rieger Yeah, no, maybe it does make sense. We are all very much the same, and also very, very different in all of that's, okay. There's another, I would throw a monkey wrench in this train of thought. But there's even a subset of folks that talk about the natural eating should really mimic what is naturally available during the season, where you're at, for you to optimally be absorbing the right kind of nutrients. Like if you're eating a fruit that shouldn't really be available that time of year that probably isn't best for your body. I've not seen science behind it, but maybe there's something to it. I've no idea that's a whole nother topic, but it's interesting because that's how a lot of people try to figure out how to get healthier.Ken Brown That's Why anytime any celebrity comes out with a cookbook, somebody's gonna buy it or anytime some new diet is because we have not figured out exactly what the ideal diet is. And I will give what the health credit that they did show that there is lots of lobbying lots of money. To try and make sure that our US government, the FDA, the USDA, things like that, that are looking out for our best interest. Really, there's, I was a little bit shocked to see the people that are funding some of these charities like the American diabetic Association, the American Heart Association, and Susan G. Komen. A little surprised. There's a lot of money accepted from fast food companies and things like that. Eric Rieger Probably not really interested in the results. This more or less the continuation of lots of customers,Ken Brown Although I will say that for the right price. I could just see you and I year from now and be like, Eric, this is the new Big Mac sponsored by McDonald's.Eric Rieger I don't think so patna. I'm not going down that route.Ken Brown Oh, I almost died number of the time you're telling the whole story of you were trapped when you almost died? Yeah. Your near death experience.Eric Rieger Oh on the run the rock.Ken Brown Yeah, where you almost got waved to death.Eric Rieger Yeah, yeah yeah that was almost the end of Marie and I for sure yeah.Ken Brown And I gave you my near death story of wrong turned into a McDonald's drive through.Eric Rieger Yours was scarier. Yeah no i don't i don't see us being sponsored by McDonald's,Ken Brown I want to try this if everybody gets a chance to do this number one, if you look up fasting, specifically a prolonged fast, it's remarkably healthy for you on a cellular level. It's not there to lose weight. It's not there to do anything but it's the turn yourselves on. When I'm fasting. And I'm like walking by a TV. I want to say 80% of the time it's a food commercial. It's Pizza hamburgers or fried chicken or something here is I'm paying attention. I'm hungry. Wow, just all the commercials visually are just coming at us with food.Eric Rieger What's weird is it's more appealing to me to learn what restaurant or eatery features are really good tasting salad with good lettuce. And I know that's not how I thought when I was a teenager as a teenager, I wanted the fried chicken or in every stomach is fried chicken tastes great, right? I mean, it's, it's good. But as I've gotten older, and I my body doesn't just accept anything that I put into it anymore, where I'm just happy and I'm sure a lot of our listeners feel the same. I've been conditioned that I want to know where I can get a great tasting meal that's going to be healthy for me. So how long would it be until that becomes more of the norm in what the advertising gets the market is for people to gain attention because I always say that I feel like it's going to change 15 years ago, 20 years ago, especially if you didn't have the restaurants like modern market, unrefined bakery, taco deli, which talks nothing about except for we have all organic ingredients. For all of our tacos, but that stuff is becoming far more popular,Ken Brown Far more popular here, Bella green things like that. Eric Rieger Yeah, Bella green. Ken Brown Let's go to Galveston. Let's go to Corpus Christi. That makes it so it's super unfortunate that there is and I think in different socio economic climates you're the options to eat where was I that's just south of Oklahoma took Lucas to a tournament. Eric Rieger Wichita? Is that right? Ken Brown Bob Burnett? Is that right? Eric Rieger Oh Burt Burnett. Ken Brown Burt Burnett. Yeah. I drove around trying to find something to eat that wasn't what a burger. It was nuts. Eric Rieger Brahms and What-a-burger. Ken Brown Brahms and water burger. Yeah. So in these, you know, smaller communities that's just not happening.Eric Rieger And it's not like that there's anything wrong with an occasional what a burger and an occasional Brahms. drive through. That's not the point. But that can't be your core diet. That can't be your only core offering. And I would like to be optimistic and think okay, well, everybody else is eating great food at home when they're not eating out, but we know the stats that's not really at today's people live You don't have options like that though.Ken Brown Yeah. And that's when when you see these extreme shows like that, whether it's the plant based when you have the exact anecdotal differences where people are strict paleo and they're in great shape and they're, you know, they've their cardiac calcium scores nothing and stuff, you're like, Okay, well wait a minute, you know, and so who knows, but it was just it got me thinking that I'm going to really try and focus a little bit harder on working on a few things be a little more disciplined and not being so reactive. Watch whatever show I'm watching and then it's a watch Joe Rogan. We're going carnivore, Eric.Eric Rieger Yeah, I love meat, but I couldn't do that either. That would that would be really really hard. Who's it Shaun Baker.Ken Brown Shaun Baker was the carnivoreEric Rieger And he's all in and Jordan Peterson and his daughter to escape autoimmune issues went I think they're almost all carnivore isn't that right? Am i remebering that right?Ken Brown Yeah. I think they are. I would just be curious. You know, one of my Friends, a cardiologist, Mordecai Klein, he completely went plant based he feels like a change his diet as a as a cardiologist, one of the few cardiologist discussing that we should have him on the show to talk about it.Eric Rieger Yeah, I'd be interested in that. You know, I, there's probably nothing wrong with taking a break from meat. But I just don't think that a long term diet for success or somebody exists without meat. But that's my opinion. I just don't think so. Sounds really hard. If you're taking a bunch of supplements just to make up for the nutrients that you're not getting, or the fact that they can measure it. What is he saying you can measure a food by its certain protein content, but the difference is, plant based protein is not nearly as bioavailable as heme protein from an animal in certain instances. I mean, th

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CBD causes liver failure?

Play Episode Listen Later Dec 19, 2019 100:49

All right. Welcome to the gut check project. I'm here with your host, Dr. Kenneth Brown. I'm Eric Rieger. This is gut check project, Episode Number 26. We're going to wind up 2019 with some awesome info. What's up, Ken?What's going on Eric? How are you doing, man? Episode 26. Unbelievable. I apologize if I'm a little too sexy today because I'm just coming off of a small cold. I think the hottest people are those that are sick.Well, I'm not sick. I'm post sick. Remember, the viral prodrome. The reason why we always like pass so many viruses is that you tend to pass the virus before you even know that you're sick by the time you're actually sick. You're probably okayYeah. At that point you can go back and say I heard you might be sick. I was too back then.Yeah, exactly. Good to see you?Well, today's episode is going to be pretty awesome. We're going to tackle number one, we've received tons of email in your clinic because you also sell the KBMD CBD at your clinic, you get these questions. These have been coming in Fast and Furious over the last little over 14 days. And it's questions about the safety of CBD oil and its application. So we're going to tackle that I do need to tell everyone. Thank you. We're on episode 26 because the first 25 shows were so well supported by all of you who've been keeping up with a gut check project. We grow every single day. Paul, the guy who's helping us put together the production now and helping us spread the word. We just hung up the phone with him. We've gotten more and more downloads each week. So thank thank you every single one of you for liking, sharing, emailing, telling your friends about it. We sincerely appreciate it.We learned so much about it like today we have a new a different guests we do Instead of gutsy our little mascot or green frog, but since we do film on a green screen, he gets blocked out did not know that didn't even realize that. So now we're going to go with a dung beetle, right here? Yeah, yeah, we did. So that's Dilbert, the dung beetle,Dilbert, the dung beetle. So one of my favorite things is whenever we're bringing any patients back and somebody sees you, and they're like, hey, you're Eric, I watch your show that just warms my heart. So if you happen to be a patient and show up and you watch the show, if you say that it just makes us both feel really, really well...needed wanted, appreciated.Yeah. At least outside of me putting you to sleep. Take five or six good deep breaths. Exactly. Today's episode is sponsored by Atrantil. Your bloating relief, it's what we do. So go to Atrantil.com or lovemytummy.com/KBMD. Today it's also sponsored by KBMD CBD oil. You can find your own KBMD CBD oil at kbmdhealth.com which of course, the initials KB, Kenneth Brown, it's endorsed by the guy who's sitting across the table from me. So Ken, why is...What does MD stand for? Well, I'm not really sure.I thought it was your buddy Mike Doyle, but I don't know.Yeah, it's probably. So tell us a little bit about KBMD CBD. Alright, so KBMD CBD oil. I got involved with the science of CBD because I saw the beneficial effect with my patients when we developed Atrantil I then learned that the science of Atrantil the polyphenols in it actually augment CBD. So I'm seeing this combination do incredible things for people. So this particular CBD is one that we have researched, I've seen it work clinically. And we know that it comes with a certificate of analysis. It is organically grown, it is naturally extracted with co2, so it meets all the criteria that you want in your CBD because this is important. The rest of this podcast is going to be all about the dangers of CBD.Definitely and It's really interesting since we do have so many people who have begun to purchase CBD find benefit. It's really kind of weird what's occurred over the last two weeks. And what I would say is a little bit of misinformation. But it's more or less probably just misunderstood information and or or misapplied information. But regardless, the benefits of CBD used correctly, have been undeniable with the people who've come back through the clinic with people that we've scoped, and how well that they are doing. And so, hopefully today, we're going to provide some context on why more or less the dangers that you may or may not have read about in the news recently are really a little concerned. But we'll, we'll see. We'll see how far along we get in at the last. The last thing. Our last sponsor is the KBMD health box. You can find KBMD health box by going to kbmdbox.com. Now last week we did a full unboxing which is something I think we're going to try to do at least once a month. But essentially, if you want almost $300 of physician vetted supplements that can help you benefit your life and get them for only $147 which you would spend, not you would spend more than $147 worth of time driving somewhere to pick them out for yourself and having someone handpick them for you. Go to KBMDbox.com. What was one of the things that we had a patient come through just earlier this week, who showed us his lab results that he took to his primary care physician? So we're starting to make a difference in the landscape of health here in the DFW Metroplex and different places. I've been getting emails and calls from people around the country that will actually hear the podcast and then they'll want to sign up for the box. And what we're seeing is that these vetted supplements actually are making a difference with both subjective how they feel and objective the labs. So the reason why I chose these things is they all have third party analysis. And they all have some scientific background that actually explains how they're going to help you. So much so that I'm thinking of ordering my household, another box. So although it is the KBMD Health box, I actually I love the fact that I can get these things that I'm going to purchase anyways, they come into my house, so my whole family's on it. Now we're running out of stuff. So I'm gonna end up having to double up on everything. So it's one of those things that I feel really good that we can look at different aspects. And when somebody says, Oh, I tried X, Y, and Z, I didn't notice anything. I'm like, oh, did you try one that had a third party analysis? No. And then they do and they're like, Oh my gosh, big difference. Same thing with CBD. I mean, a lot of CBD out there doesn't really have what's on the label. And we're going to get into that because we're going to talk about what the FDA thinks about it. We're going to talk about the different media and what they're doing, and hopefully get into all that but that's the whole point of that box is I want to deliver these vetted things to your house monthly so that you can continue to improve your health. Hundred percent. So without further adieu, be sure to like and share the gut check project. We certainly appreciate all of the support to date. We're going to hop right into it. So what we've received here recently is a lot of speculation and concern from people who have said, Hey, I'm interested in CBD. I know that you and Dr. Brown have heavily studied, been entrenched with CBD and its application over the last few years. I just learned that the FDA is associated or made public a study that says that it may be hepatic toxic or bad for my liver. It's, unfortunately, it's a weird jump off point. So I'm going to kick it to you. Because immediately I had lots of different thoughts and instead of getting emotional, what did we do? We went and tried to find the sources of where this information came from. We want to backtrack on how they got to that conclusion. And I think that we can put a lot of questions at ease and even help people learn how to be a little bit more critical with the data that they receive when they receive it. Because let's face it, lots of stuff that we see on the internet, or that we hear on the news or reading the paper, it's basically clickbait. It's basically things to keep you engaged, whether or not the actual substance is worth the headlines that are written so...So what you're referring to is recently the FDA put out a statement, a consensus statement in the news and it's making all kinds of traction in the news that they're saying that CBD is not as safe as people think not only that it can be harmful. Now this has bled onto TV and my patients have been asking me about this FDA statement. Then there's been other news articles like the one that Forbes published, read said that CBD causes liver failure. Failure. That was the title liver failure caused by CBD. I want to get into all that I wanted to take a really deep dive into the science of all of this as a gastroenterologist, I'm board certified gastroenterologist, which means not only am I a simple country, butt doctor from Texas, but we actually have to learn liver disease, hepatology, I'm not a hepatologist like some of my other friends where I send like really complex things, but we at least have to understand the liver, how it works and what it does. So a lot of these articles discuss this but they don't clarify so many little things. Because and they shouldn't it's a it's a journalist writing an article they want they want it to be shared. And anytime you mentioned CBD, anytime that that is thrown out there, you're going to get some clicks, you're going to get a whole lot more clicks. If you say you're going to die from taking CBD. It reminds me of the I remember Jerry Seinfeld was on Saturday Night Live one time and they were making fun of the nightly news where they always do the promo at like three o'clock. Like five household items that are guaranteed to kill you, tonight at six.You're like what? If it was so important, they probably wouldn't make you wait.No, I'm gonna die before you put this on the air. So what I'd like to do is talk about the briefly the science of the endocannabinoid system and CBD, then do a little bit deeper dive into the liver. So everyone's going to get a primer on the liver 101 here, because these studies don't make sense unless you know, some of this knowledge. It's just sensationalism. For some of it, some of it is a little bit unfair. I think some of it is for what the FDA got, and it's there. But I just want this podcast today to be something that can be useful for industry people that can be useful for patients or people that are thinking about taking CBD and it can be useful for a subset a small subset of people that may be should not consider taking it. Yeah. So all of this is kind of, you know, for the future of this podcast, It's almost going to be a bit of a rebuttal. Not necessarily a defense of hemp derived CBD. But let's just buckle up and kick some science. This might be a little bit I don't know how long we're going to go where we're going to go with this. We're just going to feel it out and see what happens. But I at least want to be able to explain why I still believe that a lot of people should be taking CBD even though Forbes is like you're gonna die from this.Yeah. It's not arsenic people. No it isn't and I think another cool application here is there are people out there who have been on the fence on whether or not I should try CBD or is this something that's good for a family member for me? And unfortunately, there you hit this intersection, where a news headline is written that CBD causes liver failure. Well, if they've been on the fence, that's a pretty big No, no, right? So now you've taken away maybe an avenue that they were considering to help them out. What I hope that we can do with this particular episode is basically let's temper and let's see things in context. I think context is a word that as you get into sensationalism is something that is kind of the rescue item. If I could put something into context, then at least I'm giving someone a fair chance to understand the information that's before them. I don't feel like sensationalized headlines do things like that. Then again, I also don't feel like someone who shakes, hand picked or cherry pick studies is doing that either. So what I think today that we can do is fairly evaluate and talk about the process of how the liver works, and why some of these studies are or are not applicable to the nature they were presented.Absolutely. So the first one we got to discuss is what what what the heck did the FDA say? Sure. So the FDA came out and they mentioned that they've got several issues with the safety of CBD. The two main ones that they're really concerned about are potential for liver injury, and interactions with other drugs. What they actually said is that they're concerned that people may mistakenly believe that trying CBD can't hurt the agency wants to be clear that they have seen only limited data about CBD safety. And these data point to two real risks that need to be considered as part of the drug review and approval process for the prescription drug containing CBD. Interesting. Now, what I say this is because the FDA is referring to the data that was presented to them by GW Pharmaceuticals, who has a epid... eipdi..x you know?E-p-i-d-i-o-l-e-xYes, which is the first FDA approved prescription CBD isolate,Right,for seizure disorders.It's important to point out that is not full spectrum. Correct. That is not full spectrum. And there's some that's important because here later in the podcast, and think we're going to draw some comparisons and just if you're listening, just remember, epidiolex is a CBD Only isolate it is not a full spectrum product.So let's talk about what the FBA what the FDA actually does. So the FDA has a really daunting task. The Food and Drug Administration is responsible for protecting the public health by ensuring the safety, efficacy and security of products. So it is super daunting because there's a lot of products hitting the market, and the FDA has tried keep up with this to try and protect people. And let's be honest, let's look at the elephant in the room. The elephant in the room is that there are a lot of bad CBD products out there. Yep. In fact, in a jam article 2017 showed that 70% of the CBD products that they looked at did not have what was on the label and what was there could be higher levels of CBD could be lower levels of CBD. So it's a gamesmanship that's going on right now. So it is totally true that you need to make sure that you've done your homework on what type of CBD that you're actually taking. There currently is little to no regulation in the CBD industry. There is the President and CEO of Natural Products Association NPA. His name is Daniel Fabricant. He's a PhD. I love this quote. He's quoted as saying it is well past time to bring science into the equation, as federal rules require safety and Consumer Protection must come first. I agree. And we all agree with that. Sure. And I think that all companies that have reputable CBD companies, they all want that. Problem is when you have these different stories leaking out, which gain much more traction, it just starts creating a little bit of confusion misconception, and then people don't really know where to turn. So the feeling is, is that possibly statements by the FDA saying that it creates this narrative that questions the safety of CBD overall, strictly to address a few number of companies which are producing quite frankly, some crap products.What was the number that we learned the last time that we were in Utah at meeting I believe it was one out of every 23 to 24, I could be off it was definitely in the 20s. But every to every 23 or 24,25, CBD labels available for retail purchase. One is seen as a reputable well marketed or correctly labeled product, which means that even if it happens to be off a little bit, you've got 23 or 24 other labels which are just not truthful or probably not correct, don't have a certificate of analysis or are blatantly, just not even what's in the bottle.100%. There's a lot of people out there trying to take advantage of this wave that's coming. So I do not. I believe that the FDA is doing their job by looking at the data that was actually presented to them Agree. So let's take some time and break all this down for the consumers, health care providers, industry personnel. Starting with the question, does CBD cause liver damage? Unfortunately, or fortunately, because I like science we really need to talk about what the endocannabinoid system is. Because if somebody's listening to this, they're like, Well, I was thinking about taking this but I'm worried becasue it can cause liver failure. I don't know why I'm taking it. Why in the world should I be taking it? So let's do a quick one minute discussion of the endocannabinoid system. Let's do it!All right, the endocannabinoid system. The endocannabinoid system is a system which was discovered in the 90s that we now realize it's probably everywhere in the body. There's primarily two different types of receptors, but essentially, the way that I try to explain it to my patients, it's concentrated more so in the neural areas, nerves, brain and the immune areas. Although we now know it's in every single organ, that's where all the original research was. We now realize that its job, the endocannabinoid system is to produce these products called endocannabinoids. Which work as traffic cops. They just kind of get your body to get back to an area of balance. If you've got too much activity, they go Whoa, slow down a little bit. If it's not enough, they go, come on. Let's go ahead and get some more going here. So you have this fantastic system in your body that really just tries to keep balanced. Think of it that way. And you're going to hear a little bit later why I think most of America is out of balance. I think most of America needs some replenishment of their own endocannabinoid system. So that's the important thing is is that there's a dire need to try and get us all back to a certain balance, because the reality is we're getting sicker as a nation. And one of the causes could be that we took hemp derived foods out of our diet and out of our livestock diet. And there's a theory on that, that possibly that's one of the reasons why we're having more autoimmune diseases, why we're having more of the other problems that we're seeing, Well at least contributing factor.Certainly at least a contributing factor. So keep this in mind. So the the primer on the endocannabinoid system is if you're, if you have ears and you're hearing this, you also have an endocannabinoid system, and you have a higher than likely chance that you are out of balance with that. And if you are out of balance with that, then you probably could benefit from some of this. Sure. So right now you're going well, I'm out of balance, I'm going to probably benefit but I'm going to go into liver failure if I do this. So let's talk about what liver failure means. You have a genius living within you. You probably have multiple geniuses living within you.Thank you. That feels great. Sometimes the voices in your head don't say to do bad things.The evil genius. Yeah.Well, one of the geniuses living within you as this beautiful origin called your liver. So you have this and it's amazing. So to understand where they're going with this, let's talk about what the liver actually does. So we all have livers. And they work differently in every single person, and they can continue to adapt, evolve and change. One of the only organs that you can transplant a partial portion of it and it will grow into a full liver. So the nephrologist think that the kidneys, the smartest organ, the neurologists will think that the brain is the smartest organ The cardiologist says if you don't have blood, you can't think so It must be the heart. Yeah, yeah, exactly. I'm gonna say, well, for health span, smartest organ in the body is the endocannabinoid system. So eventually, we're going to have Endocannabinoidologists. Because what ends up turning out is that the endocannabinoid system is in all these different organs.Correct.They're not completely separated. So let's talk about the liver. The liver is responsible if you ever wonder what the liver does. So do you have any idea what the liver does? I've got a little bit of an idea... Little bit of an idea. So the liver is responsible for selective uptake, concentration, metabolism, and excretion of the majority of drugs and toxins, also known as xenobiotics. So let me just say that again. Basically, the liver takes the crap that you bring into the world. And it says, I'm going to convert it to something useful, or I'm gonna get rid of it for you. Yeah, it can detoxify it, or it can say, Oh, you need to be this and then you're useful. That's why I say it's a genius in your body. And it the liver figures this out, it figures out what you need, and it determines if it's a drug, or if it's a toxin, and it can turn into a better form. Now, one of the problems I have with these different articles that I've been reading, is that they discuss that then enzymatic process called the P 450 system, and they just write it like that they're like, CBD has been shown to affect the P 450 system. What doesn't affect the P450? So that's the issue. So let me break that down, I bring up the P 450 because in the lay literature without even describing what it is, it is a complex. It's called a phase one metabolism of the liver. Under p 450. It's an umbrella term that has over 60 different genes, that code for hundreds of enzymes to break down anything that comes your way. So the P 450 enzyme is like saying, Oh, I don't even know an analogy, but it's top of the funnel down. It's like you just so generic, that you can't just say that. So but they write it in the lay literature almost as a sounds sciency so I'm sure that it's, I'm sure that it's right. That's kind of my feeling on I'm like, why would and all these people it's almost like these news articles parrot each other. And nobody's stopping going, wait a minute, because as it turns out, the P450 system, not the P450 enzyme, the system breaks down almost everything that we put in our bodies. Yeah, no joke. So a lot of going back to the pharmaceutical days, I remember that was one of the biggest challenges with with any of the drugs that we detailed a physician on was, how is it affecting the P 450. And that would be something that they would be all salespeople be coached on that before they would go on calling a physician. But the truth is, it doesn't have to be a compound. It doesn't have to be a medical pharmaceutical compound for that to be somewhat important. Something as simple as grapefruit juice. Also, detectibily inhibits the metabolic ability of the P 450. So there's all there's a handful of different drugs that people who are elderly, maybe caution, don't drink grapefruit juice, because it will inhibit your ability for your body to clear this particular drug. And I say that to say this. It's not nothing is inherently just special because it does or does not directly affect the P450, almost everything you take into your body is either cleared quickly or slowly by that same system.Yeah, so they kind of imply like CBD is the only thing that gets...Not even close....that gets processed in the in the P450 system. In fact, we know that there are multiple medications that can be altered by certain foods. Grapefruit is the most common one, and that really affects like immunosuppressants tremendously and that's where it really came up. When they realized, oh my gosh, you have these different drugs, let's say blood thinners and immunosuppressants, which have a very narrow therapeutic window, you have to have these things like right dialed in. Yeah. And then people talk about grapefruit but you know, other things that have actually been shown to do this cranberry juice, black tea, pepper, even chocolate Yep. has been shown to affect drug absorption and they have been shown to affect certain pharmaceuticals. We don't even know the tip of the iceberg on this because you have to do the study on it. You have to do the pharmaco kinetics, the PK is what it's called to actually determine that which is so funny because they say oh CBD is metabolized by the P450 system. That means nothing. And so if you take CBD and or chocolate and or drink tea, be careful. I mean...I think a good analogy a seriously a good analogy is it the P450 being metabolized by the P450. It may be good for base knowledge, but the truth is, is does it overwhelm that, as you put it system, if it is overwhelming that system, chocolate, for instance, for most intents and purposes would be like a single car driving down a six lane highway by itself. It's not really if the highway was a P450 and the car was the chocolate. It doesn't take anything to funnel that that car through.Correct.The problem is is whenever you happen to overwhelm that system. And that is important to know. But I would say in terms of context, kind of the way that we started this discussion in context. It's not my belief through what I've read and seen that CBD inherently overwhelms or becomes more than a single car down that six lane highway.So not only is it just one single car going down the highway, remember that not only foods but drugs, nobody's talking about drug drug interaction.Right.So there's a reason. So I see a lot of patients that one drug may be very effective one thing may be very effective, but there's so many variables like for instance, drugs, the sex of the person plays a role, you may have different levels, the age of the person and any diseases can all affect this whole system called the P 450 which produces enzymes. So not only that, but then genetics play a huge factor, alcohol intake.Alcohol intake, all of that. I mean, genetically, this may be why some drugs work on certain people and why they don't work and others fact there's a whole field of science right now where people are trying to determine the genetics ato go, Oh, you're going to need a higher level of whatever Plavix which is one that they've actually looked at. Or you can, you're going to take less. So we this is a whole field of this beautiful science where we can go Okay, genetically, you're going to be predisposed to need more medications. So when these enzymes get used up, basically if you've got this one chocolate, which is a car, one on six lane highway, and then you add fluconazole, which is an antifungal, that's an but that's not a car, that's a semi now and then you add alcohol, which is a minivan could be ccould be a couple minivansand then you do whatever something else, but you can see that the liver has to try and process this right. So what happens is it becomes this once it becomes a traffic jam. Then people start getting angry, they start honking their horn that is a rise in your what we call lfts liver function panels liver function test Yeah, so AST and ATL are the two ones that we always talk about, that's exactly what the FDA was referencing. So I want everybody hear this. When you overwhelm the liver with multiple cars using your analogy, then honking starts and the honking the warning sign is this rise in AST and ALT. So, for instance, your body can adapt to it. We've seen this all the time. If you drink alcohol on a regular basis. you build more lanes, you build more lanes, you get really good at metabolizing alcohol. Build tollways. I'll use myself as an example.Not with alcohol.With coffee, Okay.I always have to laugh. Whenever I go to the my own doctor. They say how much coffee do you take? I just write obscene amount because I've down regulated by receptors or I've had the ability to ramp up my my livers ability to convert that coffee into an inert thing and there it is. So you see it as an anesthesiologist or as a crna. I mean, describe what your experiences whenever you try and put somebody to sleep using propofols, different medications.Yeah, well, I mean, definitely, if someone says that they happen to be a large consumer of or a consumer of large amounts of alcohol, it generally takes anywhere between 20 and 30% more of an agent to put them to, to sleep safely, say, But back to your point of body habitus, for whatever reason, even just something as simple as someone being a redhead fair skinned, those people generally take more agent to make them go to sleep. Yeah, let's go ahead and clarify this. This is a well known thing in anesthesia. You're not being prejudiced? No, not at all. No, they literally just for whatever reason, the metabolism rate of someone who's fair skinned with red hair is typically higher than the average calculation and you can go through any types of weight based medications that we use to bring sedation to someone and generally fair skin redhead folks just take more. Is that interesting?Yeah, it is. So that is more than just anecdotal like they've actually done some studies on this and they've actually shown probably because whatever lineage, they come from Scotland, Ireland, they have a higher P450 to metabolize that particular or a higher subset of the P450 systems. So just keep that in mind. So when you take certain foods or drugs, everything's competing for your liver, to do to just say, hey, fix me, you know, figure out what's going on. Fortunately, it is a badass organ and the liver is tough and it can handle a lot, the largest solid organ that we have in the body. So usually it can handle everything. Now the most common example like we've talked about, if you take grapefruit juice with certain immunosuppressants and things then that particular combo because those drugs need exact or how they were manufactured need exact metabolism numbers. Not only that, did you know that like nutrition plays a big role. So, high protein diet will actually affect your P 450 and malnutrition will affect it. of course it will. So those are all of our paleo friends over at paleo FX and such those guys have revved up p 450s. Eating a lot of protein working out a whole lot, they're able to do this. Unfortunately, malnourished people probably can't tolerate as muchNo and they aren't they aren't they honestly they don't have the supply to rebuild the enzymes that are that are used within the P 450 I mean it's just malnutrition is going to deplete all different types of systems, not just the liver.So in the intro, I kind of mentioned that we're getting sicker. And so let's use nutrition as an example. federal policies tightened by the controlled substance act of 1970 essentially banned the production of industrial hemp during the war on drugs effectively we made hemp CBD illegal and put it under the umbrella of cannabis cultivation. Now what were we were talking with Will Clyden of O-hi energetics right, who actually discussed this and he said some cool stuff on this. He back before this when they were they were using hemp and hemp has been used for ever like since we landed in America, hemp has been using hemp has been used in China for thousands of years and all this other stuff that we were feeding because it's a fantastic crop. It's it detoxifies the soil. And it actually works. It grows quick. It's a great crop industrial. What were we thinking making it a banned substance, I don't know, separate discussion. But they've got data to show that when they were feeding chickens, so for everybody out there I had a patient today who said I said Oh, she was suffering from some things and I think CBD would help with and I mentioned Hey, have you ever considered CBD Oh, I would never ever, ever, ever do anything like that. I am not like that. I said, Okay, that's cool. said hey, let me tell you something. Do you know that before 1970 we were actually feeding animals like chickens and cattle. One of the primary things that we would feed them would be hemp, and it's been shown that you can take a chicken egg and it had over 250 milligrams of CBD, right so right now if you're somebody that just spent $200 on your CBD that has 300 milligrams in 1968 you could've just had an egg.A three cent egg.I know 3 cent egg. And I looked at the literature and I and I could not find anything that said death by egg otoxicity. It didn't so everybody that's sitting there thinking oh my gosh, no. I'm not going to do CBD. We were having CBD in our diet. A great Great example, to learn a lot more about this and do a deep dive. Our friend Chris kresser had Will Clyden and the CEO of O-hi, O-hi energetics on and he went into this tremendously. It was so cool. It was just like I just it's crazy that we stopped like, and I as a physician have seen that we are getting sicker as a country. So in 1970, we've got since 1970. We've got more chronic disease, we've got more dementia, we've got more autoimmune disease. coincidence, like we said in the intro, maybe it's at least a contributing factor. And now we have the FDA saying that CBD can be harmful yet it was in our food supply up until 1970.That's nuts, dude.It is nuts. And it doesn't make sense and if you look at mean hemp seed, birds eat seeds, birds consume seeds, they do all kinds of things where they can they take in product, What's the matter? No, I'm just looking at I'm trying to make sure we get through everything.Okay good, but I mean they eat everything and people have been consuming eggs from not just chickens they've been consuming eggs from all different birds on the planet for that long. The fact that we've restricted hemp growth etc has only taken away one of the natural things that birds were eating.If you're if you're really interested in this like I said go to Chris Cressors podcast where he's got Will Clyden on there is really cool wills smart dude Chris is super smart dude. So those guys those guys kick some crazy knowledge.Right?So that is it's weird that we're talking on this episode about CBD causing hepatotoxicity. And we've already shown that the liver's pretty badass, right? It can do a whole lot and we've already shown that the endocannabinoid system is necessary and since 1970, or up until 1970. We are taking in significant amounts of CBD in our dietRight.Weird.It is weird, but it's not so weird when we get down to why everyone's alarmed. So you want to get into a...Now let's go ahead and look at the studies. So that is sort of the phase one of this podcast because now we're going to start geeking out a lot. So I hope I didn't hope I didn't lose everybody with a but you kind of need that background to understand what we're going to talk about next.Sure, you definitely that background.Alright. So what they're talking about is the FDA published this revised consumer update. So this is the consumer update that they put out there for everybody detailing the safety concerns about CBD products. Now, this was based on the studies provided by GW Pharmaceuticals, GW Pharmaceuticals has done multiple different studies looking at different things to get their FDA approval. And I'm going to say right now, that kudos to GW for being the first company to step up and really try and make something for a group of people with intractable seizures have an alternative. Kudos to the FDA for doing their job and looking at the data that was presented to them. What I'm going to do is go next level and say, Well, you didn't look at everything. That's the bottom line here. So I'm not bashing anybody. Let's make let's make certain of this. Sure. So there have been several randomized, controlled and open label trials that studied the effects of epidolex, I'm going to call it epidolex from now on it's just easier, which is a 99% pure oral CBD extract on patients with refractory epilepsy. So this in turn led to the FDA approval for two diseases, dravet syndrome and Lennox-Gestaut syndrome. So if you recognize those names, bless you, because you're dealing with some serious stuff, It's a serious seizure issue. If you don't know those. Count your blessings. It's one of those times to go well, no matter where you're at in life. It's like well, thank goodness that I don't have to Deal with a child that has this because that's, that's a really big deal. These are intractable seizures. So they looked at the data on that. And in these studies, the kicker here is I'm going to say it again, getting back to the lane highway, the patients maintained on their stable drug regimen with a median of three anticonvulsant drugs. That's important. It's super important. Three anticonvulsant drugs. So when we use the analogy of the car on the road, imagine a six lane road. And three of those roads. Three of those lanes are double semis.Yeah, that are closed construction... Or closed, Yeah, that's more likely or closed. So let's talk about that. So when we're talking about three different agents used to control seizures, some of those agents would be and I'm assuming here, but probably Depakote, probably Dilantin, also known as phenytoin, or fosphenytoin, which is seravex. There's a handful of anti seizure medications and through my knowledge, all of them, all of them have been recorded as raising the enzyme levels used by the liver which of course would lead to ALT and AST elevation, showing that the liver is essentially working overtime to long term process these drugs right or wrong?Correct. Correct, which is exactly what the FDA is supposed to do. They're supposed to look at this data and go Okay, so let's just look at the study that they're talking about. So the FDA accumulated this data, and they looked at what GW presented GW presented in isolette of CBD, not a full spectrum. And the dose they ramped up to 20 mg's per kick 20 mg's per kick. What that means is a guy like me would take 1954 milligrams a day.That's a lot more...of CBD isolate. Now I see the effects, beneficial effects of taking KBMD health CBD 15 milligrams twice a day,that's 30 milligrams,that's 30 milligrams.The exact dose of what makes people feel better is very argued because all the data coming out of Israel shows that a lot higher doses, but I'm seeing effects at these doses So let's be real quick let's stop for context. So right now at this intersection what we're what you're saying is with a full spectrum and we said this at the beginning of the podcast that what GW Pharmaceuticals has with epidiolex is a CBD isolate and what they've done...You're saying epidiolex now that's funny. Yeah, whatever it is, Well, because I started with that. Then you told me no, that's not how you say it.I think we should switch it up the whole time. EPA max the way it was edimax. What they did is they were able to establish that almost 2000 milligrams for you would be the ideal dosage however, you...isn't that correct? That's the dosage that they went for or the dosage that they felt was safe, Safe. Okay, I'm sorry. So but but on the upper end of... That was what they were aiming for on everybody. In essence, though, from where you have had beneficial effects, you're talking 60 times that amount, two months worth, is what they are saying the safe level would be in one day where you're finding the beneficial spectrum. So just just in terms of context, full spectrum, CBD, one 60th of the dose that they're saying it's a it's a safe level is really all that you need from our experience.Yeah. Now in GW's defense, let's look at the data. So in dravet syndrome, seizures dropped 39% and in Lennox-Gestaut 42%. So... that's good. So they probably did their homework and said, well, we need to get up that high to actually help that so I don't know anything about that. I'm not a neurologist. That's where it's at. But I'm just saying that when we look at that dose, no average consumer is going to be able to consume that Much CBD in a single day, unless it comes through this 2 full grams a day is more than most take Yes,yeah. Now here's the problem 94% of the people had side effects. Okay 94% at the highest dose compared to 75% placebo, kind of weird. So there's just a huge placebo side effect profile that doesn't get discussed at all.Did they say what it just had a curiosity do they state with the placebo was for the control,They did not stay with the placebo was oh, I take that back. I don't know what they use, but basically they left people on the same medications. So, essentially, let's just look at this and say okay, but the good news is, most of it was not a big deal. Most of it was what the FDA also discussed beyond the liver tests and beyond the drug metabolism. They also said Oh, CBD can cause nausea. It can cause drowsiness. It can cause all these other kind of nuisance things. That's what they're referring to right here. It's interesting though, that have a side effect profile assigned to a placebo that's that exceeds around the 30% range, because that's generally the throwaway number. Yeah. So we've gone twice away from the throwaway number. And they've had they've had reported side effects, which I'm not trying to over draw conclusions here, but it could at least indicate that side effect profiles assigned to CBD in this study probably weren't solely to CBD, Well, you're dealing with one of the highest risk populations you can get your hands on, when I did clinical research and when we would do a moderate to severe Chron's study. The placebo arm would have tons of side effects because the disease is bad. That's what's going on here also. So most was not a big deal, upper respiratory tract infection, somnolence, decreased appetite, diarrhea, blah, blah, blah, blah, blah. But the one that they focused on is the increase in amino transferase concentrations. This once again was a revised consumer update, they put this out to the public and their statement is increase in liver amino transferase concentrations when I just got done explaining what the liver does. Did I ever say amino transferase concentrations? No. I said liver enzymes. right? frickin talk to the public if you're going to release a consumer paper. yeah, liver enzymes. AST ALT. This is hiding behind scientific garbaly goop. It's like you're doing half science half anyway. But but whatever. So a patient show up and they're like, I need you to check my amino transferase concentrations. I'm like, Whoa, why? They Hand me this, this, this news article. Right? This is what we're trying to address right here. So what they found is that in the higher dose, 20 mgs per kg, there was a rise in some patients in three times the level which is significant, so if your normal is 20. You can be 60 if your normal is 40 it can be 120. When patients come into me and it's three times the level it sounds alarming. Do you know what happens when somebody gets hepatitis A acute infection? It's way more than that thousands of times the level when somebody goes into foaming at failure there AST and ALT will go from 40 to 10,000.AST and ALT have risen for almost everyone who's listened here, way more than three times throughout their lifetime multiple times in acute or in very isolated settings. It happens with illness.So getting back to your highway analogy, which I think is really cool analogy. I'm glad you came up with that. Thank you .Getting back to the highway analogy. 80% of them were taking a drug called valproic it matters Depakote Yeah, that matters. That matters a lot.It's when you take these medications, which is why at the beginning of the show, I said you're more likely don't have to worry about it. But if you're on certain medications, keep it in mind. Now that being said at the lower dose didn't see this stuff. So there is a dose dependent usage of the P450 enzyme you can if I give you one drink, or if I give you a bottle of tequila 512 which in my opinion is really one of the tastiest, most fantastic tequilas you can ever get your hands on. It is delicious. It's delicious. I'm gonna I'm gonna digress right here. Oh my God, Tequila 512... Also sponsored by Tequila 512Tt was really good seriously, ummm in every single person with liver test rose.They went back to normal if they decreased the anticonvulsant or decreased the CBD. So either one it went back to normal. So it wasn't number one, it wasn't permanent liver damage. More than likely correct they were able to return back to normal. And number two, it was simply A case of an overwhelmed P450 pathway more more than likely.So you want to get really confusing? Not really but we might as well try. I don't want to but here's what's really interesting, then they kind of get a little geeky. So GW presented their their stuff and then they showed that the P450 in this enzymes and they went into will, the CYP to, 2c19 CYP three a four can inhibit the CYP blah, blah, blah. Those are all just cytochromes people. Those are all just cytochromes It's under the umbrella of P 450. That's how complex this is. Yeah,It is nuts how complex. The highest plasma concentration to CBD occurs within two to three hours after exposure to the Epidolex. With medication, so timing of these medications going to play a role, which actually got me down a weird rabbit hole where i started thinking. We haven't done this much analysis on what happens if you take your Ace inhibiter and you take your cholesterol medicine, timing wise PK analysis on different people and everything. Because when they do these pharmacokinetics, they do it to get the FDA approval, they do it on people that are healthy, that they can understand it. Let's put this into context again, if you're listening to this you've ever taken tagamet. Have you ever thought about when you take your tagamet, you probably only take it whenever you're afraid that you're going to have acid problems, right? Cimetidine?Yeah, guess what? It's also known as a high level p 450 inhibitor if it's over consumed. So I guess what I'm saying here is, there's probably way more alarms being driven over something that yes, is handled by the P 450 system, but is far less invasive or it's much it's a much smaller vehicle on this highway than some of the other things that the alarms are not sounding over.And then surprise surprise after I just got done talking about the liver and the genetic variability and all these other things. When they looked at the pharmacokinetics there was tremendous variation. Hmm. Weird. Yeah. Odd, right? So and anybody that's listening to this that is a, a pharmacist or is a scientist or like Well, yeah, duh. Like I know, duh. But why put out such an alarming statement? Yeah. Without context.Yeah, yeah, you're right. So it for Okay, so it's a little bit of clickbait stuff, right. And so maybe even the journalist who wrote it doesn't understand specifically, the implication, they may have only seen P450, written somewhere turned to a health care provider and said, What is this? Well, that's indicating that things are rising up, they freak out. They write a headline that says CBD causes liver failure. I just learned that from this health care provider. So I'm going to write this piece.Well, that we're going to get into that. The liver failure. This is still just the FDA. Oh, yeah. To the consumer. So I hope that the FDA looks at this and says, You know what? That's right. All that stuff that was just being said it's right. But we didn't have the time to do it. We couldn't sit there put that on paper, we'd lose everybody. I get it. It's quite true. We all we all but we all have a responsibility, much like any doctor to try and explain. You and I have this ability to have this forum to reach hundreds of trillions of people.Yeah. It eflects in our subscriptions on YouTube. They so many trillions of people subscribed, they started his back over to about 200. Yeah, so every time we got trillions, they start back over. Yeah. So So anyways, so what what you're realizing here is exactly what we're talking about. When you put stress on the liver. The liver honks its horn and does a little rise and the lfts goes, Well, hey, guys, maybe not so much. Can we just back off the traffic a little bit and see what's happening here. So additional studies have shown that levels of the anticonvulsant drugs actually caused the daily effects. So now we start wondering that the that the CBD may actually rise some of the anticonvulsants and then you have more side effects from that comes down to the same thing we're talking about how many things do you want to tax your liver, that's the bottom line. To summarize high dose of a pure CBD isolate, not full spectrum, while using a mean of three other anticonvulsants can cause temporary rise in liver tests and affect the metabolism slightly of the anticonvulsant. Of note, it did not happen at lower doses. So one more time, if you are on an anticonvulsant discuss with your doctor and make sure that you stay well below the 2000 milligrams a day. Yep. So this whole thing of Oh We're going to block the P 450 the P450 is So frickin complex, it is nuts. So anything you want to add to that, because I'm going to move on to the thing that I really want to, like kind of make fun of No, not really, I just want to say that I think that the FDA, unfortunately, is a very important and serious organization within our government. And I think that for all of the flack that they take their, unfortunately, with any other entity, there are limitations on what it is that they can do. And I do believe that they try their best to fairly ascertain and address situations as they are presented to them. Regardless of how frustrated that one of this may get is we don't get a result from them. A lot of it is just simply because there's not enough manpower. Oh, absolutely. They get thrown everything think about, think if you're in an organization where you know that 70% of the crap that's out there needs to be pulled off the shelves and you're limited. It's a government organization. These people making these statements are MD's. I'm really limited fortunately, I have well, we have the show where I kind of enjoy looking up some of this stuff. Fortunately, we have some friends of ours that are that work in the nutrition industry that are fantastic at researching articles. And some of that gets gets brought to me I want to make sure that we all get better this is the whole purpose of this.Hundred percent.I want to help the FDA and help GW I want to help the CBD industry. I want to help all of it. But let's just talk about this because something super weird happened. And this is the one that got the most press A Forbes article came out that promoted a mouse study and made the sensational claim that CBD causes liver failure.Yeah, that's kind of what I was referencing earlier. I may steal the thunder but yeah, you're right.Yeah, so this is you're exactly right. In the intro, you said it was clickbait. I really after looking at this study after pulling the study, because how many people read that article are actually going to pull the study.Well is the is the person who wrote this study that well versed in reading studies like that. I mean, that's that's an important thing. I mean, they I think that probably even the author of the article feels like that they are doing a service to the reader, but probably doesn't understand. And if they do, then shame on them, but if they don't, I think that would be a better explanation doesn't fully understand how to read the study and the quality and the qualifications of that study to make a statement like that.Yeah. And you know, this, this could be an arguable point, I'm sure that the person that that wrote this feels very strongly that what they said was right, the bottom line is the goal of this study was to investigate CBD cannabidiol hepatic toxicity, meaning liver issues in an eight week old male mouse. So they they took a group of eight week old male mice, and then they gave them a CBD that they produced. The CBD that they produced and Will Clyden will just jump up and down when he hears this because he decided Is this on Chris Cresser's podcast. The CBD that they produced was used to extract using hexane, which is a molecule that is known to be hepatotoxic. Yeah, you're not supposed to have heaxane. Don't do that! Will Clyden talked about the fact that if you find a CBD with an outrageously high amount of of CB, if you find a full spectrum CBD with an outrageously high amount of CBD more so and the price ranges, okay? Because what they did is they extracted that with hexane in a cheap way and threw it in their bottle and said, there you go. Now you can check that's got 10,000 milligrams of CBD or whatever. And it's really interesting because there's so much going on in the industry like this. So this particular study out of the University of Arkansas, took the CBD, or they made their own CBD using hexane which is a hepatotoxic in itself and in their certificate of analysis. It was there and then they gave it to these mice. Second thing neatI don't even know there has to be a second but we can hear it. Because I mean seriously, that's, that's like saying, I know your stomach hurts. You should take this Pepto bismol. And then I don't tell you that I've broken up some glass shards and have you drink it and you're like i'm bleeding now! What's going on? I'm like, I don't know. Yeah, but you only paid half the price.I made it myself.Which, by the way, that last batch of propophol that you did in your bathtub is working phenomenally. I'm sure it is. Now we do not make propophol in our bathtubs.Alright, so the second issue. If we have any mice that are subscribers to our show, or listening, I would like you to have your children removed from the room at this moment. Because they took these poor mice, and they gavaged to them. Would you mind defining what gavaged is? I think it's when you kind of force feed somebody I don't think it's willing. That's your I think gavaged something you kind of threw one at me there I think to gavaged someone you basically introduce a funnel to the esophagus and well you kind of get after it, don't you? Yes, I'm currently gavaging my mic right now trying to figure it out. I just undid everything. You're gavaging our ears with your, your microphone adjustments?All right, so gavage is they forcibly give these mice?The CBD extract? Yeah, I don't think it's comfortable nor pleasant.No typically through a tube feeding or down the throat to the stomach is how they generally gavage things. A quick side note, now because I'm now all of a sudden I feel like I'm living in a glass house when I was an undergraduate student. I actually did my first surgery on a rat and we took out their adrenal glands. And I'm just saying that so I don't want to sit there and pretend like I'm not done mean things to an animal. But that was when I knew immediately I could not be a bench researcher. I did not like that. At all, now I was like, I need to, I want to heal. I want to heal. I don't want to hurt these animals, but it's it's a whole separate discussion. So anyways, so they gavage these animals with different doses, and it's really interesting. Now in what they call their defense, they call it allometric dosing, which means they're trying to get the body weight to human weight ratio appropriate. I've read some rebuttals of this article where it is a joke, you just can't do that. And when I read vitamin weed Michelle Ross? Michelle Ross, when I read vitamin weed she dis... she specifically discusses why research on CBD versus mice is very difficult to do because the weight basing the endocannabinoid system is different, all these other things. So allometric dosing being said, assuming that they're saying it's right, so the dose would be the equivalent of what they gave and What a human would give So I'm doing the allometric dosing, which I think is actually higher than what it actually is separate thing. They took mice and they gavaged them with zero milligrams of hexane derived CBD 246 milligrams per kilogram 738 milligrams per kilogram or 2460 milligrams per kilogram of dirty CBD. It doesn't make sense dirty CBD isolate. So for instance, in a horrible alternate universe where humans are now the test subjects and we have large mice which are running tests on us, and they decided to gavage me with the same thing. That would be the equivalent at the highest dose of 241,080 milligrams of hexane derived CBD isolate. I'm not even sure what the hexane would do it 240,000 milligrams 242,000 milligrams.No I mean that being the more or less than now at this point, it's just an additive. It's just I mean it's it's not an excipient It's a straight up additive. That would not make sense at all. Oh, it's crazy.It's poison.This article came out in Forbes and said CBD causes hepatotoxicity. Also hexane causes hepatotoxicity.It is nuts. Alright, spoiler alert. The mice suffered hepatic toxicity and death at the highest dose. Shocking... You know what? I also hear it's bad to have breakfast cereal with not milk but drain-o. Just something that I'm gonna go out on a whim. Don't think you're supposed to do that. It just doesn't make sense. It's It's It's not. That is not an apples to apples comparison if you're talking Okay, so we talked about it earlier. reputable CBD source there is no reputable CBD producer that's going to have and Will special shout out to you it's going to have hexane as a byproduct or an excipient in their full spectrum COA approved which is also why KBMD Health with powered by olyxenol hundred percent is does not have that. I mean they do co2 extraction, which is the important thing which is a reason why we partnered with them to make that product. So we are the one out of the 23 or 24 that is the safe and trusted COA back no hexane etc etc. Doing this study is not an apples to apples comparison on what would happen because who knows? Who Okay, I don't get it because GW we already did that study. They determined that 20 Meg's per kg which is still a shit ton. It's a lot. It's a lot. Yeahis the safe maximum dose. These guys went times it by 100.Yeah, they did.And see what happens? Yeah, it's it's a bad it's a bad comparison. I mean, yeah, honestly, if you wanted to find out if CBD plus hexane causes liver toxicity at a ridiculous amount, top to bottom, then that's a great study outside of that, since nobody does it, I would say it's a bad study. Speaking of road, that's a road to nowhere.Yeah. And so study like this, uh, like you had mentioned is essentially it's not science. It's clickbait. Yeah. And right now that that author, that journalist is just kind of laughing. He's like, I know, and now you're bringing it up, and I'm going to get another whatever, because that's what people are trying to do. They're trying to get attention at this point.So at that point, good for you, you got to click but I would be truly interested if possibly that particular journalists would say, you know what, I didn't fully understand it. I mean, that's okay. Let's look reading studies, right? There's there's a study to reading studies. I mean, we heard that we heard the breakdown that kresser did on Joe Rogan is he Twice had to address his approach to completely different topic about the the plant based diet and then how he had to re approach that with the rebuttal. All that just simply to say, there is a science to reading studies and being really good at understanding what is and is not applicable and then how to find studies that you can compare to each other for good meta analyses. So what we're doing right now is I'm telling you that maybe sometimes there aren't studies, but my anecdotal evidence, I have a busy practice, you hear the patients, we hear them talk I listen to them, when they say that doesn't work. I go, Okay, I'm not publishing it. I don't have time to do that. I wish I did. If I published everything that we're gathering data on, if we're looking at, you know, just so many different things, CBD is just one of them. We've got I love I'm a huge fan of brain.FM for the ability to use sound to change your mood. I Would love to they're unpublished, a lot of studies on stuff like that. There's, there's tons of stuff. So when people go, oh, the studies aren't out there, there is something to be said about the Socratic method, or I'm sorry, the paternalistic method, the way that medicine used to be where the guy in front of you that saw thousands of patients, this is the method that he has. You see me scope, I mean, there's a difference in scope techniques.So they, although some may even still say it qualifies as anecdotal, I will say that there's objective data in both in a scope, somebody can't just come, anybody can come to you say I feel better. Anybody can even if they don't mean it. But they can't make the disease disappear from the imaging that we see in their colonoscopy, or the the mucosal samples that you take. And that's something that's completely objective data. That we see. So those are the everyday results that we see from these types of applications where you just, look it's not made up whenever we okay full pleasure when we first started looking at CBD, I thought was bullshit. Who you looking at?Just anybody who's out there. But when we first started talking about it, I didn't believe it. I was like, man, let's see, because we've been down this road before but we tried new, new without throwing a bunch of things under the bus. We tried new or innovative different things and high hopes. And unfortunately, low expectations and the expectations get met and the hopes are never never realized. The opposite for me personally occurred with CBD over the last three and a half years. And that is it actually stinking works.Dude, I knew that we were onto something with Atrantil, because after we did the initial studies, everybody came back and said, I want more. I knew that I was onto something or I was not on something. I knew that CBD had a viable place in my practice, because I bought and the story goes all the way back which is why we work with which is why it's powered by elyxenol right now, when we went to paleo FX, and I ordered a couple cases and I just gave them away to patients. That was not cheap. Not because I was sitting there trying to be altruistic, not because I was doing charity. I'm like, I don't know. I didn't. And I told everybody, I don't have a clue. I haven't even looked at this yet. All I know is try this. Tell me what happens. And when about 80% of them came back said I want more. And I went, Okay, we're onto something. And that's when I took my clothes off the deep dive into the science and went, holy cow. Yeah,this is crazyUp until that point, I just didn't know there was a whole lot to it. I mean, it really didn't. And then the fact is, oh, and to clarify, it's not like Brown just handed out CBD to just anybody who came to the clinic. You literally just like we did with Atrantil you found very diseased patients to say and who had gone through a gamut of different pharmaceuticals and weren't finding relief, and suddenly they're like, this is working for me. Tell me more about it. And I was, I was blown away.So let's talk a little bit. So we're I'm over here going well studies I haven't published and everything. Let's talk about a few studies. So I've got a Mendeley account, I know how to look at PubMed. I know how to get a Google Scholar, I just want to talk about a couple studies have come out recently. And let's kind of compare it and see if it still makes people concerned that they're going to die of liver failure.Sure. Alright. So in the Journal of Clinical Pharmacology published in 2019, the this was actually a study, also sponsored by GW Pharmaceuticals, as part of the process of getting the FDA approval that the FDA did not reference the best I can tell they did not reference this. This is way more complex and it gets super cool, because what they're looking at is the pharmacokinetics or how CBD is actually metabolized by that beautiful genius called a liver. In high doses in people with liver disease. Yeah, they went through the trouble to take high doses of CBD and give it to people People that did not have liver disease had mild liver disease moderate and severe. This was ballsy to say the least, because using a product like this in somebody with liver disease is is risky. This thing could backfire and it could shut down the whole process. Here's what's nuts, the pharmacologic and safety of a single oral dose of 200 milligrams of epidolex, which is the CBD isolate. They were assessed in subjects they had eight people with moderate or with mild disease, six people with moderate and eight people with severe and then they had this collection of normal people. Blood samples were collected to check for the pharmacokinetics This is how drugs are looked at. They give you a drug and then they check your levels. Basically, the blood concentration was higher in the hepatic impairment and they describe it in nanograms. So the nanogram comparison is that it's a little bit higher in those with severe hepatic impairment. But this is what's nuts there was no increase in adverse reactions. There was no change in blood levels. So basically, the only adverse reaction that they found was a little bit of diarrhea. And it all happened in the mild hepatic impairment. So the FDA had mentioned Oh, studies have shown that it causes diarrhea. What was really funny about

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Exercising is a Waste, New Website, and Turkey Day

Play Episode Listen Later Nov 27, 2019 70:55

Alright, welcome to episode number 24. This is the Gut Check Project with your host, Dr. Kenneth Brown. I'm Eric Rieger. What's up man?Man I'm super excited we are going to do this together.Yeah.Here we're starting to work the few kinks out we had that really cool episode that we did with SurePath which is just gonna be launched and then Dr. Marisol which got launched last week. We're getting some really cool episodes building up here. So I thought that this could be an episode where we circle back with each other and get reconnected. You know, I mean, I'm still recovering from you abandoning me when Dr. Marisol came here and I was alone.Yeah, I know. I was I was knee deep in talking to tons of dietitians up in Philadelphia. And so that's okay because up there they like cigarettes. I learned a lot of cigarette smoke and Philadelphia along with cheese steak but it was it was a great episode and of course since we've been at the new studio we have had CBD takeouts Jeremy kender. We've had Dr. Marisol and we've also had Patrick Brewer as well as Tim power of SurePath and now we're going to experiment with having a reconnection and talking about some research.You know, what was really cool about that having Tim and Patrick on, that they're just so freakin smart at what they do.Definitely .And I'm so stupid in that world, that that's, I'm you know, it's just being around people that are specialists in that field. It's really cool.And that gets me, man, honestly, it's really cool to hear somebody else who has, it really is it's a holistic approach to how you handle your finances and your money. And so many people get caught up in the race of making sure that they have their work, their job, their family items planned out that the last thing they think about is how well am I making certain that my money is not only secure, but working for me. And if you haven't checked out Episode Number 23 with SurePath that is actually a great primer, whether you use them or not, be sure you take care of your stuff. It'll, it'll take away the stress.It's so interesting when you start thinking about money and how money can create stress, or the lack thereof can create stress. And in fact, you know, forget that I have a lot of friends that have sold their businesses. And then suddenly the stress of what do I do with this money pops in which most people would love to have that problem, I get that. But even that in itself can be an issue. And so then you have the fact that money plays into this. And any type of stress can affect your intestines, your guts, whatever. And that can lead to dysmotility can lead to all different kinds of things. So we want to act like we have all these different fields and we want to act like that this is my such and such guy. This is but really we all have to be together. Because if my finances are going south, I'm going to be stressed out, I'm not going to sleep well. It's gonna affect everything. And if your gut isn't good, and you've got the resources, you're not going to enjoy it, because what do you have if you don't have health?Yeah, no, you're exactly right. And I would even go even a step further when, when I was just getting started off on my own and Marie and I just gotten married and you don't have a lot of money back then. It seems like stress was a little bit less because basically, let's face it, that extra hundred dollars, we knew what it was going to go to, it was already kind of spoken for. And so you, you kind of knew where your money was going. And then as you build your career and you a little bit larger, and you don't really stay in tune with what's happening, that's where the stress comes in. So having someone help you plan where you're effectively using your money, regardless of your income is a huge stress relief. You don't it's never too early to turn someone like that.It's so interesting that everybody always talks about the simpler times the simpler terms, but when you're in the simpler times, all you're doing is looking forward to the time when you can actually not sweat the next bill. So this kind of comes down to that whole aspect of just living in the moment.Sure.Just be true to this. I'm in the moment with you right now my brother.That's rightJust in the moment. So we got big news before we even get into research. What happened today?Oh my gosh, this is so exciting. So in the CBD world, everybody's being jerked around by having these processors where the banks won't do this and we got a website we're having trouble running these different credit cards and stuff. Today we actually got a processor square processor.We did and and for those of you who have been loyal and allowing us to manually process when your credit card doesn't go through because of various bank rules, it all ends this week. We've got a new website, we've got a new processor, no more of having to chase around to get that kind of stuff going and we got cool things are going to come because of it. Black Friday specials Christmas specials, you're going to be able to get KBMD CBD trusted, certified, etc. at a breakneck cost. What am I trying to say here at a, at a breakneck cost doesn't make sense...I always think about breakneck as speed but yes, you can have this CBD sent to your home at a breakneck speed. At a substantial savings because we have been so excited to get this out to everybody. When we sit there and talk about CBD, one of our sponsors KBMD health has CBD, we also have Atrantil, my baby there, the coolest thing is those two things work together. I talked to so many people and every time I meet somebody, they're like, Yeah, I don't really understand that. I see all these stores popping up and I try to explain it. Here's the bottom line. You have an endocannabinoid system. This system, if you live in the United States, you have a very high likelihood that it is not optimizedRight.All this does is allow your body to bring you back to balance Everybody tries to make it too complex. Everybody tries to make these claims. That's not what we're going for here. My role is to get people to just get back to their balance. And then we can work on the other issues. Because it's an uphill it's a complete uphill battle. If I'm trying to fix your gut, and your anandamide a fancy scientific term of one of your own endocannabinoids is not at its optimal level. You're not going to function that way. So everybody says, Oh, I want my thyroid to be this, oh, I want. I want to make sure that my adrenal glands are functioning and my cortisol, I'm telling you, you're chasing your tail, because if your endocannabinoid system is not optimized, all this other stuff, and all this money you're spending on supplements, probably is not doing nearly what it can be doing for you.Definitely. And so this particular episode since it's scheduled to be released on a Thursday, that's next week, and that's Thanksgiving. So this is actually going to be released at the early part of this of next week. So this is Thanksgiving week. Tune in KBMDhealth.com. We will have black FRIDAY SPECIALS running through the weekend all the way until What do they call it Cyber Monday? We'll have specials exclusive to KBMD health shoppers. KBMDhealth.com. Tune in, save money trust the source. It'll be KBMDhealth.com.KB as in boy, M as in Mary, D as in dog, health.comThat's correct. Go there. Check it out. And well, I couldn't be more excited for everyone who's who's helped us get this far.This is it is so much fun to have this transition. I personally like the whole live aspect and I think that will eventually go right back to live once we get all the all the kinks worked out because we have to understand that we're we moved the studio Special thanks to all the people at Mojo and Spoony that have come over and helped us and helped us set this studio up but I love the fact that it's so convenient because it's close to my office. And I'm selfish that way.Yeah, it's the same drive for me regardless. It doesn't really matter. But one of the things, I want to start interacting with our audience a little bit more, and one way to get them interacting is to really just give them silly discounts. We're going to unleash this physician recommended CBD at a breakneck pace with a breakneck price.That's a really bad adverb I threw in there. Lots of neckbreaking. I don't know where...Cuz I think I'm Busta Rhymes or something. I'm not really sure. Not a very good not a very good adjective or adverb, whatever the right word for that.Well, anyways, this is super exciting. This is very, very cool that we can sit there and get this physician recommended CBD in the right hands of the people that actually need it. So that the people that want to hear some science, and I want to, I want to interact with our community, so that you know, share it, share this podcast, share this idea, share this email that we're going to send out If you actually subscribe to us, we really want everyone to start getting back to balance. That's the bottom line.That is the bottom line. So today what is it? Oh, hey, what are you drinking their?A little hop tea? We had this last week on the show. I love this stuff. We gotta we have to find these guys.We do have to find those guys. I think that they're out of Boulder, Colorado. Luvich if you're listening help us out on that. So hop tea. Free plug hop tea. Good stuff. So...Well, let's get back to this. Just you and I now, we don't have to worry about other people's schedules and things. Dr. Marisol had a plane to catch. And we were running a little late. Our podcast went a little long for a little bad about that. What's going on with the family with you and the family?Oh, wow. So we're getting ready for we're getting ready for Thanksgiving. Of course. That's that's coming up. That's going to be at my brother's house. But second from that Marie and I are both super pumped because it's our oldests senior year in basketball and our youngest is now on the JV. They both just kicked off this last weekend playing against a...ok so my boys are classified in their high school as 4A. It's a top 10 program in the 4A right now. So 4A means what for everybody that's listening. Texas has classification...So we've got6A all the way down...We've got NBAYes4ARightCollege.And then on down.Yeah it's just between D league and NBAGot it.Yeah, it's really exclusive.Yeah.So but Gage's varsity team is ranked in the top 10 for for 4A currently and they were matched up against another top five team at a 5A over the weekend and Mac's JV team got to play the JV team at the same school. So Mac got to play first. His team was back and forth, back and forth, back and forth. They ended up trailing and losing by 2 at the end. Huge, awesome effort. I mean, for a 4A school top notch to be going against a 5A, it's a big deal.So then two hours later, Gage, Gage's team matches up with their varsity against that same 5A school squared off they actually were trailing by almost 10 fought back took the lead, go to overtime. They tied up in regulation ended up losing by two. It was awesome. It was a great sparring match two high caliber quality high school teams, both stacked with with good kids who are who listen to their coaches, great athletes, but more really just kind of pulling the same direction. So it was it was a blast.That's awesome.Isn't that awesome seeing, seeing that many good kids out there and you were just I mean, you look at the level of athleticism that's it's just insane.Definitely. I mean and the Sulfer Springs kiddos who came to play against Gage's and Mac's squad. I mean, you could tell they they are well disciplined. They work really really hard. I'm certain that they'll go far just as their projected so uh anyway for them. That's probably the biggest thing on our news at the moment and Gage, see since we've been on the air, he has picked his school. He's going to go to the business school at Texas Tech.Yeah, there we go. So It's exciting and he prepares to graduate.Hook em Raiders right?That's ridiculous. No that'sNot right...No, yeah, that's silly, silly all the way around. What's going on y'all?Well, so we have a November's our birthday month my Carla turned 13 Lucas turned 15 and Loida turned 29 for the 10th year in a row or something like that. I don't even keep track. Before I forget Marie also has a birthday. Her birthday was was earlier in November also.So as you you know, I'm and we're going to get into this because what I want to do so on today's show, I know that we're starting out talking about some personal stuff, but I do want to talk with some science. I'm gonna get back to our roots the way we were doing that at Spoony. Geek out a little bit without a guest we've, I've got something I want to talk about in the news. I got a book review that I want to do.Oh yeahAnd we haven't done that yet.What's up Tony Yun.Yeah, we'll start doing that. We're gonna do a book review, and then get into a little bit more really, really cool science and talk about why..Well, really you're wasting your time exercising,That, that would be news.Did I just throw you off a little.Yeah, I was not expecting that.Yeah, basically you're wasting your time exercise. So we're going to get into that. So make sure that you here because I've got some interesting data. Im always looking at data. So one of the things that I've always talked about is I'm not a big fan of how everybody sits on their phone all the time.And I had to break down. I because of the traveling of the kids, and because of the way that the world now communicates. Both kids now have phones for the they've been the last holdouts in their school. So both Carla and Lucas now have cell phones, iPhones to be exact. So Loida got an upgrade. Both kids got phones and I'm just sort of dealing with that fact. And so Lucas got his phone. Loida and Carla went out of town. And or I'm sorry, I take that back. Loida's car broke and Carla went to school Lucas decided he want to go play tennis. And we just adapted and persevered did what every other kid already has been doing for years. I was just shocked that he just did it on his own and downloaded the Uber app and then spent the whole day just sort of ubering himself around for things he wanted to do. Tennis, yoga, he took 4 Uber rides in the first day that we left them alone with his phone. Like, okay, you're exploring the world.Me either.Yes. It's pretty amazing though. If somebody went to time travel and see that kind of availability, I don't even think they could comprehend much. That's kind of amazing.Oh, man. I mean, we can get into that a little bit more. But speaking of Uber, I'm, you know, just something to go off topic a little bit. I heard a really cool podcast this morning. Yeah. While I was on the treadmill.Okay.Even though I just said that exercise is worthless. Yeah. So, while I was on the treadmill this morning, I was listening to a podcast, happiness, something rather I'll figure it out but really, really well done. It's a Yale. It's a Yale psychologist that was discussing the fact that we, she interviewed. I forgot his name. Do you know that the inventor, there was a guy who worked. I don't remember exactly where he worked at the story of this is irrelevant, but it is relevant because it's here in Dallas.Okay.He was sitting in line at the bank, and it was taking over an hour. He's just like, I need to be back in my office. He's an entrepreneur. He's like we're developing things. Sure. And he went back and said that that is just a colossal waste of time. And as it turns out, he is the inventor of the ATM. Oh, he's 90 something years old. He lives here in Dallas. She flew to Dallas to interview him. And this totally gregarious and cute and his wife has never used an ATM.How?Never used one because she said I didn't like how it depersonalized the banking system because I like talking to the teller, and then this gets into socialization and how we just keep putting ourselves in a bubble.Sure.And the reality is being antisocial is just as dangerous or not being social with others, or being...Everybody thinks they're being social, but they're not being social on the phone, you're not actually looking at somebody and saying, Hey, how are you? And what they looked at is that multiple studies have shown that, oddly, when you interview people, they say that they really want to be left alone. So for instance, there was a railway system and I don't remember it was New York or something, where they did a poll of everybody and people basically said, I want to be left alone. So they made quiet cars. And this guy did a study. I'm going off the cuff because I just I listened to it just a few hours ago. I'll give the, we can do better show notes on this and I can tell you about it but it's really interesting.Okay.Because what it comes down to is the more that we make ourselves, our lives convenient, the more and more we don't know it, but we're emotionally isolating ourselvesI believe it.And the more that we emotionally isolate ourselves, the direct correlation to happiness starts changing. So to be happy, you have to be part of a group, you have to be part of a tribe. And that's why I think us showing up here and having the KBMD health tribe, be part of it, share it, get people moving, talk to us, because that is a social interaction. They did a study where they took a couple groups of people and they said, I want you to go on the on this train. It's like a commuter train in Philly or New York or something. Don't talk. Sit down to somebody and engage in a conversation. And then sit down with somebody engage and then just listen, ask questions and listen. And so they were trying to see, completely across the board, those that actually engaged with other humans had a much more pleasant experience. And they didn't think that they would, because the perception of humans is, well I don't want to ask, I don't want to say hi to somebody on a random train because they're going to kill me. It's this worst case scenario type thing. So the train took a took a poll, and they decided to make quiet carts based on the pole. But this same Professor went to them and said, you know, what you should really do is make interactive ones.Yes!Chatty, ones, whatever. And they said, well, we we actually did something like that we had like a, like a, an interactive car. And it was too crowded all the time. Okay, so you're so contradicting yourself. Humans want to be involved with each other. I only bring up this briefly because with Lucas getting on Uber and doing that, it's just, you know, you're not getting out there again and doing this, the apps are too easy. You can order groceries to your house, not interact with anybody, but just sitting there saying, Hey, tell me your story. I want to start what I'm going to what I'm going to do is I'm going to carry around a journal and I just got done reading The soulful art of persuasion.Oh, Jason's book? Yeah.Yeah. What's his last name? Jason?That wasn't good.No, it's not good. I just, I just finished this morning also. So I've had a really good a very enjoyable morning, I read and worked out did some work. But what it basically shows is that when you have a story, and you can tell it, people are much more engaged.Right?Jason Harris.Jason Harris, that's it. We're going to need to see him in person. And...It's and incredible book.It's a great book. But basically, when you can tell a story, you can engage with somebody and get them to. He encourages people to carry around a journal and when you meet people and they get a cool story, write it down. Just write it down. It's an engaging thing. So I'm going to start doing that. I'm gonna sit in line you're waiting in line. Instead of being in line and making it worthless. Turn around, say what's up.Yeah, you're exactly right. The cool part about Jason's book, The soulful art of persuasion is that it really is just a guideline on how to engage with someone. It really is not about, you know, using subversion to win them over. It's about the human gain trust about being trustworthy, and people will want to interact and do things with you.We will do a full book review on that one because I took a deep dive on that.Yeah.Speaking of book reviews, I think you know this guy. I do!It's big Tony Yun.Our friend, Dr. Tony Yun. I read his book recently. It's called playing God, Anthony Yun. I gotta admit, I was a little skeptical as being a doctor. I was expecting just straight up. Grey's Anatomy style. I did this save this life. This is you know, Blah, blah, blah. What was really, really, really cool was that it's really heartfelt. It shows him from the beginning shows him in in early residency, where he describes in detail being stuck doing but pus duty. He's doing his residency, he goes all the way from having, you know, having to do these but pus things being broke.Yes.You know, trouble with that. He's got some really great stories through his residency, like the time that he had his wife come up to the call rooms whose overnight and they tried to get intimate, but it really smelled like blood and poop and people were running around outside and there was lots of yelling and stuff and he kept getting called out and she just basically said, this is never gonna happen.Yeah.Which is very different than a Grey's Anatomy episode.Yeah. Every closet is a place to hook up.I know. But some really, really, really funny stuff he puts in there, but also he puts some very intimate things. Like people dying.Right. Like the time that he was nervous, the time he didn't know what to do. As I was reading it as a physician, I thought it was really cool because I'm like, I get this, this is exactly how I would think he was talking. He was talking about how his phone would ring. And it would be this difficult patient or a lawyer or something in his heart would stop. And it was just Oh, and he had to keep it together and still go through with it. And he was it's really heartfelt.Sure.And then ultimately, you know, some wins, where he did some really cool things. And that is pretty much from a doctor's perspective. Yeah, high five to you, Tony, because you're honest about it. He's said everything, the hard work that it takes to get there. And then if you're not a doctor, because this isn't really meant for doctors, I want everybody to get this book, because you'll understand what your doctor went through to get there.And definitely and knowing Tony and his approach to life, how this this book isn't just a facade. I mean, he's a great guy and he puts his patients first, he's definitely altruistic in his approach to how he cares for his patients. And yeah, good job, Tony.And he, he also talks about a system where there's a lot of doctors that don't think like he does.Right.You know, I mean, he's, you know, his trademark is the, you know, America's holistic plastic surgeon. He's a lot more than that. I mean, he's a talented surgeon and all that, but looking at what he went through to get there. It's like, everybody that you see that has a successful business. That only took 10 years to be an overnight success. It only took 16 years to be a successful plastic surgeon.Yeah, only.Only.YeahThat kind of thing. post-college. So anyways, that's our first book review Playing God. Go to Amazon pick it up, Tony Yun. I actually found it to be a really enjoyable, easy read. And I think it's going to be very important for both people in the medical field to read it so that they go Yeah, I'm not alone. And then everybody who's not in the medical field to go, oh my gosh, my doctors probably been through a lot to get to where he's at.Definitely Yeah, good job Tony playing God Tony Yun or Anthony Yun, MD. I think you can find the Amazon and really anywhere.America's holistic plastic surgeon. Awesome. Well, hey I was going to tell you briefly about a very interesting documentary that I've got to finish. To full disclosure, I tried to watch it yesterday in preparation of today's show and I fell asleep. It was a it was late in the evening as I turned it on and.... That's what resounding cool review there, buddy.Yeah, it has nothing to do with the content has everything to do with that was a little fatigued and i fell asleep, but it's called Tell Me Who I Am. And it was just released on Netflix within the last few days, I believe. But here's the premise. It's two twins. I think they're in their late 50s. And essentially, they've grown up and one of them has a pretty serious accident that gives him amnesia. And it's its global. He doesn't really remember much of... How old was he? I think he was in his 50s. And his other twin to care for his brother begins to fill in the holes for him. But he learns that his twin that had all the information basically only told usI think he was 18 when it happened. Oh, the accident? Yes, I'm sorry. I know I meant the episode whenever they talked about...I want to know when he was hit. Sure. No, I think the accident was whenever he was in his teens, you're correct. But he begins to fill in the blanks for him and doesn't tell him about all the bad things that they've been through together. He just tells him the good stuff. And what's really interesting is that as the twin who had amnesia has been filled in, he notices that as he loses his dad and then later loses his mom, that the affinity that he has for his mom and dad is far different than the way that his brother is experiencing everything. And his brother was basically protecting him from basically it was a it was a childhood of abuse, that he didn't tell him. Oh my gosh, could you imagine that weight on you? No.Where you both went through it as twins. You both probably sat there for 18 years and talk to each other about the horrific vents that were going on. Yeah.And then you have the opportunity to go, I'm going to give you a new life. Yes. And so basically his, his twin that didn't have the accident, loved his brother so much. He didn't want to burden him with basically what he was living with. And he's basically in his own little hell there. And coming from I mean, I had a great childhood. I did. And for those of you who didn't, I'm really sorry that you didn't get to experience that but I feel for you because this guy has a real weight around his neck. And he saw... Did your brother tell you that you had a great childhood?Yeah, that was it. But you could tell that, that he has this weight around his neck of all this information and he decided for his brother that that's that's freedom. I'm not going to tell this to you. And so now he's going back and just basically processing what has happened but even at that rate he's just processing as being told to him he doesn't he doesn't really have the memory of it. So fantastic documentary to get started on. I'm looking forward to finishing it to see how they round out and basically reconcile the information but Tell Me Who I Am Netflix. It's pretty powerful.Well, let's talk about that because that means that his world looking seen probably pictures and stuff like that. Yeah.Painting this whole thing. He's happy. It's a perception, which shows the power of the mind. He's still although he has amnesia. Sure. There's deep subconscious battle scars in there. And it's fascinating that even the subconscious portion of it was wiped clean. Yep. And in I like when I hear this, I, I just go, wow, there's two sides of this one is you get a chance to go I mean to let your brother live a completely clean life by letting his brain do it, which shows how powerful the mind is. And then the flip side is that the brother that's still dealing with the regret and all this other things, has the ability. If you're, I mean, if you meditate enough, if you're able to control the thoughts that you can control those negative emotions as well.Yea. It's not just you don't, you don't just need to thump your head and have amnesia. You can actually do some different things. There was, I mean, we talked about it before, but I think that's one of the reasons why ayahuasca, psilocybin, and these different studies that are going on at Johns Hopkins right now, because what it does is it gets you to just stop for a moment. And then you get to have control of your brain again. Yeah. Because in my opinion, When you have these perserverating thoughts, if you're somebody that's out there that is depressed if you're somebody that's dealing with PTSD if you're dealing with emotions, childhood stuff that we never get rid of, but it gets ahead of you then that dominates your conscious thought. This is something where you can show wiped clean you have total control. He had a perfect life.Yea check this out. So when you look at the age marks, I mean, the wrinkles and whatnot, the one who remembered everything. He definitely deals with stress on a completely different level. And he's a little heavier. I mean, it's it's all of the things that go along with perpetual stress. This guy deals with it because it's turned into anxiety. He's not happy as we're certainly not as happy as the one is his brother has been liberated of all of these horrific memories, right? So,yeah, it's it's a...Well it's super fascinating that I realized that that is something that I have to quit saying every time I every time I get around you and I start thinking of different stuff. I always say it's super fascinating but it is super fascinating. Sure. When they've done studies where they look at people and I say, okay, Eric, for the next 10 seconds, do not think of a white elephant.That's all I'm going to think about.So these different psychologists have shown that they put bells on the table. And, and when they told a class to not think of a white elephant, just if you do hit that bell, bing, bing bing bells started going off in the more they went off, the more they did, which means that the more somebody did this, they triggered to not think about that, then all of a sudden, you're associating don't do this with the memory that I'm not supposed to do this. I'm not supposed to do this. That's what our brains do during PTSD. Sure. They just keep bringing that bell and just hitting it faster and faster.Well, our lizard brain that's the protective mechanism, right? I mean, you're you learn what danger is before you learn what pleasure is, you because to know what danger is is survival. To know what pleasure is may or may not pay off for you but to know what danger is, is survival. So...Yeah, yeah, absolutely. That is really interesting. Yeah. That is interesting. I came across something pretty cool with that. Let's start taking some science now. In the news article just came out. A woman in China became temporarily blinded in one eye because she was on her phone all night.That is weird.It is weird. The article describes her staying up all night playing on her phone. And then suddenly she went blind in one eye. Went to the emergency room and scans revealed that she had large patches of blood in her retina, blocking her vision. And she was diagnosed with valsalva retinopathy.Really?Yeah, valsalva retinopathy. So this is because I'm trying to picture this now, because I just got done saying that we gave the kids have phone. Everybody has their phones are on it a long time this person was on there all night long and then woke up blind in one eye valsalva retinopathy. So the article actually discusses that it was described in 1972. And I took it a little bit further and I actually found that there's documentation of valsalva issues in health in 1704. Okay, it was the treatment of choice. Basically what valsalva is, is you try and breathe out on a closed glottis meaning no air is coming out. So you're like, oh, man, that's a fancy term, everybody valsalvas if you're going poop you're valsalvas.Yep, when you bear down.When you bear down Yeah, you bear down and...Lifting heavy things bear down you actually valsalva when you're sneezing real hard, you're not letting it out. Even you can have cough. There's something called micturition, and defication syncope, when people push too hard to pee, or they push too hard to poop they will actually pass out. And that that's called valsalva syncope. Right? And so this one is valsalva retinopathy. So in 1704, it was first reported that doing the valsalva maneuver, where you push down real hard was a way to clear out ear infections because it would blow the eardrum and pus come out. That sounds cute.I know it's, it's wild, so technically, it's when you're trying to breathe against a closed airway. But what I found fascinating about this one was what was she doing with her phone? That she literally blew out her eye hole?I don't know. That's what I can't quite wrap my head around. What about the valsalva retinopathy is related to the phone?That is the funny part they didn't get into it. Like my first question would be like, what app were you playing? What website were you on? What were you doing? What made you so worked up that you're like, aaaghhhh.It's like really intense Bejeweled? I mean what do you do? I don't even I don't even know that game. I've just seen it. I mean, the connecting dots? I'm not really sure. Facebook really hard?I know like Facebook super hard or you just you just can't stand that tweet. Yeah. So you just startSnapchat. So anyways, next time you're up all night and you're valsalva or next time you're up all night you're on your phone, and you start getting super emotional. Just breathe. Yeah.Just breathe or you don't want to blow your eye hole... Put the stupid phone down.I mean that that's crazy. I mean, she's able to attribute the long term use she that's self reported. They don't know that. I know. So what is she doing? That's why I'm much more curious what she was doing on the phone to create that. Or she was on the phone while on the toilet. I saw some comments.That's the problem. Well, I saw I saw on Instagram we posted our Dr. Marisol social media thing where basically you know, I asked her in the first 10 seconds, Welcome to the show how you pooping I'm pooping like a champ. I'm pooping like a queen. Somebody said is awesome. I'm listening to this while pooping. Yeah. I mean, I think if everyone's full disclosure greater than 90% of the people are opening up their phone while they go in into the throne library. Well, this is something you know, I love treating hemorrhoids in my office. If you have any hemorrhoids, if you have any rectal bleeding, go see your doctor, but I can fix those hemorrhoids. And we do it painlessly, and have about 90% success rate with using something called the CRH medical system. Right? We're gonna bring those guys on the show. They've already reached out to us because they want to start collaborating on a few different things. But wow, I almost feel like I should. Well, everybody already has phones, but had I known how effective phones would be to create hemorrhoids? Sure. I would have like, started sending phones to all my patients when they first came out. What do you think the percentage increase in time is that people spend on the toilet because of an electronic device that will occupy their attention. Oh my gosh... It's had to have gone up.There's, there's there's a famous meme on Reddit cuz you know, Reddit can be a time suck. You start scrolling, and it's one guy does the 3d picture of him holding toilet paper going it's time to wipe.But it's so true man. I mean, people go in there and they they get to scrolling on their phone and they get into a chat room or they Snapchat whatever they do. And I'm guarantee that people there's a significant amount of more time people spend on the toilets in the because they've got that phone.Oh, absolutely. We're, I mean, the way that we eat and everybody gets constipated. I mean, I'm actually I'm morally torn. I probably never disclosed this to you before.Yeah, not about this. I don't thinkI love treating hemorrhoids.Okay. But the horse chestnut and Atrantil fixing bloating and constipation Sure.Takes away some of that hemorrhoids. business. It does.I'm torn. But it's natural.It's natural. It helps bloating and constipation and change about habits and I'm over here trying to find more people with Hemorrhoids and I'm fixing them so it's like I'm I'm sort of competing against myself here so I'm morally torn.So get Atrantil and if it persists they can come see you and you can fix it. There we go.Yeah Nice. Yeah so, but anyways, yeah she blew her eyehole.I don't know how you do that or if there's a Chinese character for that blown eyehole.I'm telling you I want to reach out to this woman there was no way she did a playing an app she was pooping or she was doing something else that created her to valsalva. I don't know.Don't you think it's kind of weird though earlier you were talking about the interaction of people. And I was sitting there thinking that a lot of people now when they interact with their friends, they'll do it daily through an app a social app, Facebook or Snapchat or Instagram, something like that similarly. However, if you get texted if you get a phone call or if you get a ding from one of those social apps, I sense frustration in myself when it happens and I happen to be engaged with someone that I'm talking to. If I'm talking to someone and my phone begins to buzz, I'm annoyed by the buzz it because it's interrupting my personal interaction with someone else. I don't get upset with someone who comes up to talk to me while I'm finishing up a text. I will fully put that down. So yeah, let's talk because this is annoying. It really is. I'm ready to get to the point where I can throw this thing in the river. I can't stand to be on the phone. It drives me crazy.The more that we can interact face to face, the more that we can start realizing that we need this. Humans want to look each other in the eye. They want to smile. The vast majority of people that strangers that you talked to are not trying to kill you. They're not trying to you know the chances are this is funny, the chances are the vast majority of people calling your phone are trying to sell you something trick you into something...It's all spam calls now anyway.It's a con it's the biggest con game ever. Yeah. That you can sit there you're better off walking up somebody just being like hello.You know I'm going to challenge KBMD health community do this. Let's see if we can't do this with our our newly launched season as we continue forward. If you watch Gut Check Project, send it to a friend have them watch it, talk about it, begin to watch it together compare notes. What did you learn? Send us topics together. Hey, my friend and I were talking about x y and z after ya'll brought this up. Could y'all address this? Let's make this more the community that we did in the first season that was 1 through 20 and let's let's do this together because what's the point in just consuming this by yourself? We want to help people's health. Start a social community hashtag Ken's a jerk. Yeah As long as we know that we don't care. Right?There's, I mean, people getting out and doing things. In in Jason's book, he talks about a hairdresser who was really just didn't really know how he could give back. And he realized I'm a hairdresser. So he went out San Francisco, I believe, and spend an hour and did somebody hair. A homeless persons hair, sorry, not somebody's. Oh, wow. Went out and did a homeless person's hair. And what what he found is, is that he learned about this person actually stopped and said, hey, and the guy had a story. And there's a lot of different like, we're all human. How in the world are we 99.9% the same DNA and we can treat each other so badly. And we can ignore each other and I can pretend like, well, I'm sure Eric doesn't feel bad when I say something or ignore him. I mean, if there's one thing we can start doing is just pulling people in and going, hey, we all feel the same. As a doctor. I love this part. I stick my finger in so many butts and they're all the same? Yeah. We're all 99.9% exactly the same on a genetic level. That has to be some common ground.It's gotta be common ground. I mean, okay, when we're scoping and if you've ever been in to see us do we just wheel them back and then just have them get into position? No, maybe next to never do that. We almost always try to engage with every single patient that comes through so that they feel like that it's it's a conversation.I don't think you're trying to I mean, I've seen you do it 10s of thousands of times, you're like so what do you do? Where you're from? Those are my first two questions everytime. What do you do? Where are you from? And then they get to choose so it's not you know, full I'm because I'm unemployed I'm not gonna say that. I'm just gonna say I'm from Rockwall or wherever, which is I never I never know where they're from. But it's a way to get people to go hey, who are you? What is it? And then later we'll, we'll start talking about remember that guy that will the attorney from Greenville or whatever, yeah. Oh, yeah. Yeah, I'm like, that was really cool. I ended up going to blah blah blah this is how you, this is how the network is. Yeah. It's, hi. I'm Ken. Who are you? Tell me something about yourself.When people come through there I mean it would be so easy. And in fact, we could even go faster through the day if we did not try to get personal. But that to me is no fun. And there's no reward in that.You know what, let's do this. So don't be surprised if you come to my clinic or you come to the endo center, we should make a poster to put...we'll frame it and we'll put it in my office and over the over at the endo center that says loneliness is just as dangerous as smoking. Ooh. Turn to your right. Say hi to somebody. Yeah. Find out why they're here. They're all they all have something in common. It's something with their guts. I'm going to do that. I'm going to challenge my waiting room to get off their phones and to just start interacting with each other,Yeah, no, that would be awesome. Wouldn't that be cool?Yeah. And it probably the time would go by quicker. I mean, think about it you, you get to visiting with people, time escapes you because it's pleasurable. It's not and you're actually picking up things you're interacting. It's not hold up when you're simply in this over time you get fatigue. I mean, you do. Well, that's one of the reasons why we have this show. We love bringing people on. Yeah. And learning from other people. Definitely. And, you know, please hit us up, let us know what topics you want to hear, broad, whatever, do more on finances, do more on, on supplements, do more on whatever and we can we're now reaching out to people, we're meeting a ton of really cool people that are so knowledgeable, and they're reaching out to us. And they're saying, hey, I want to come on your show and talk about protein because I think people get it wrong. Kind of like the whole game changers Netflix thing that everybody's really controversial with Yeah I'll tell you my experience with that. I saw it and I was pretty I was pretty moved. I was like, wow, that's interesting. So Loida and I did it, we did seven days. She still on it, she loved it. I made the mistake like I always do just jump all in and I went to Whole Foods found their vegan section and got every meat substitute possible. Tried to eat for seven days. Holy cow, the thing I kept forgetting, I'm like, man, I am swollen. I am just not feeling good things are just not right. My joints hurt everything. They use a lot of gluten and that stuff and I'm gluten intolerant. And I wasn't taking Atrantil with it because I thought it was plant based and I was gonna do this so that in itself to be a really kind of interesting topic where let's let's bring a protein expert on somebody who knows that If anybody's watched game changers I'm I mean it seriously I'm really interested in what people thought of the show, and what they think is actually practical. So I don't for one second think that we can't eat less meat or certain types of meat. I honestly I don't know. But I don't think that were made to not eat meat. I mean, I just I don't know think that we had the canine teeth for no reason it just doesn't make sense. Meat tastes good.This is it's a fascinating that because it's such a well done documentary that it's one of the few things that has really knives over forks that kind of thing I get it food inc. those those are all really interesting.What was the other the other one was just horrible was what the health that was out of control. What the health or whatever but but this one is this one shows elite athletes being plant based. I really I mean, I want to be an elite athlete I want to do you know, I mean I wanted to but man I jacked myself up trying to go all in and you know, so there's so for me maybe there's a limit i'm i've done well paleo the last six or seven, eight years, and I tried to just shift it and my body kind of fought back at me I did not feel like it was an anti inflammatory diet with me but I but in I realized I probably did it myself because I think I was doing a lot of the substitutes. Like like a true vegan would be like hey, you gotta like really make sure you get enough protein from your legumes and this and that I just jumped in said, let's just all do plant based. What's the guy's name? the orthopedist. Shaun Baker. Shaun Baker. The carnivoreHe's all meat all the time. Correct. Correct. I don't think that's right either. I mean, it's just it No, that's not good either. Because cauliflower is pretty tasty. I mean, that's the thing. I mean, like it's, it's good. You can have great vegetables and great meats. I think it does matter where you get your stuff from. And it does matter where your food sources are and if it can be trusted, but to totally write off all vegetables to totally write off all fruits and totally write off all meats is is nuts. Just, you just gotta be sensible. Stay away from the genetically modified stuff. Stay away from the crap that you know is crap. Just eat good food and you'll probably be okay and don't eat as much. But the crazy thing is, whenever you end up commiting to eating clean food, you tend to overeat way, way less. And it just, I don't know, it seems it seems silly and dumbed down but that's if you're going to start somewhere start there.Well, definitely nutrition is super hot topic. People want to get healthier. Sure. That's a That's why every time I walk into the gym, I always see a bunch of people sitting there on the ellipticals banging it away.Yeah. Oh, hey, what about the exercise thing? Exactly.So let's talk about it.So it's really, I'm going to be going on vacation soon, gonna be going to a beach. And like a lot of people that start realizing that, you know, we're sitting in November, I'm like, man, I'm going to be on a beach. And I could probably, I want to shed these 10 pounds right now. Okay. And so I started looking at a few things and just kind of saying, Okay, how can I shed this and then I came across a 2007 study, which was really interesting. It looked at...it was in the Journal of obesity, where they took 200 sedentary people, and they had them do what they called moderate aggressive aerobic exercise. They divide them into 100. That said, you keep doing what you're doing, sit on the couch, and they took the other hundred and said, you're going to do 60 minutes of aerobic exercise six days a week, and they follow them for a year. So 52 weeks. They got 100 people that were sedentary to do exercise and actually get into a little bit where they said that a lot of the exercise was made for them to come in and do it in person. So they watched Alright. Or they had pedometers that they can log in and kind of watch it and see how much they do. And they had these people do it. It was amazing. The weight loss was absolutely incredible. So they had 100 people that were sedentary sitting on the couch and they said keep sitting on the couch. That's it. That's it. And then they had another hundred people and said, Get off your ass, you're going to come to 60 minutes of aerobic exercise six days a week. Was it that machine with a belt that goes around does this really fast? They actually do not get into exactly what they did. Okay. But it was either some sort of jogging or the elliptical or just a typical gym stuff that people do. Okay. Massive amount of weight loss, guess how much the average weight loss was in the aerobic group? Are we talking about percentage or pounds? Pounds! In the aerobic group? In the aerobic group compared to the one over compared to the couch sitters.10 pounds? I don't know. In a year. Well, I don't know! At 60 minutes, six days a week?But it sounds to me like that's a lot of fatigue and build up just but i don't i don't see it being a long term solution. Yeah but they worked out for a full year. I mean, there's a lot of people sitting here listening to this right now that might be on a treadmill. They might be on an elliptical. I mean, I think old me would think that that would be hundreds of pounds. But I it sounds to me like a lot of stress.It's gotta be hundreds of pounds. It's not though. It's three pounds.Yeah. Three pounds. So and the diet didn't change for either group. This is just adding in the exercise, is that correct?So it's just adding in the exercise, but there's there's a lot of what is what is the, what is the epidemiologic term? Causality versus correlation? Okay.Causality versus correlation. You know, did they lose the weight because they did the exercise? Did they not lose the weight because they did the exercise? Is it true, true and unrelated, and there's just other factors going on? So you gotta take everything with a grain of salt. OkaySomebody who's really good at explaining this kind of stuff and breaking down the sciences. Peter Aditya the cardiothoracic surgeon has his own podcast and super smart guy, but he's really big about looking at studies that make it into the media. And then said, well, let's look at the causality versus correlation. Let's look at this. Let's look at the code. You know, the confounding factors. So this has a lot of that. But what it does tell me is, a lot of people are trying their asses off to lose this weight and get on the elliptical because they see everybody else doing it. As it turns out, this particular study in 2007 went on to say, well, in these 200 people, they only lost three pounds in a year... Of exercise.Six days a week. That's nuts. That's nuts. Then there's a really cool podcast. So then I started digging deeper. I was like, This is crazy. How can you only lose three pounds with exercising like that? So then I found a podcast called Science Versus and actually, the topic of it was exactly this. Does exercise help you lose fat? And so they had a couple experts on it's a very well done podcast, super high level. And they brought in and they looked at a 10 years study. There was a meta analysis that had over 5000 people and 5000 people Okay, that's pretty big sample size.Huge. Where they basically showed that aerobic exercise was not very effective for weight loss. In fact, across the board, almost everyone gained weight. So once again, is it correlation versus causality? Meaning does A cause B or are A and B separate? So did they exercise and gain weight? Or did they exercise and nothing happened? Were they going to gain the weight? Anyways, there's a lot of variables, but 5000 people they looked at, and they really couldn't even conclude that aerobic exercise helps people lose weight. There might be a lot of reasons for this. It's pretty hard to burn calories. People don't realize that. So when you were talking about well did the people what did they do? Did they change their diet? Did they do things? Well, it's human nature to go well, I was on that treadmill for 40 minutes for 60 minutes. Then I'm okay with having the doughnut now.Yeah.You stop and think about it. A bagel 400 calories? You need to aggressively run like 40 minutes to burn off that 400 calories. Oh, wow. And people that we just lose that we just don't you know, we talked about the phone earlier how life gets simpler. All these things you're ubering instead of riding your bike and doing all this stuff, we're making life so much more convenient. But we're also in this calorie excess no matter what you do. I mean, you really got to ratchet it down, you start looking at it. It's crazy. So aerobic exercise. So over this 10 year period, almost everyone gained weight and it wasn't muscle. The type of exercise was variable. They couldn't control that but kind of makes you think because you know, you could argue well, where they do it hit where they doing this, no, it was just typical aerobic exercise show up and do this. So exercise, not a weight loss thing.I wonder yeah, but I am curious about doing resistance exercise and lifting heavy weights. If that... It didn't even get into that at all this is strictly aerobic. Strictly really aerobic, yeah.So,Well it doesn't really surprise me though, whenever you look at we've talked about this before in previous episodes and of course just whenever we're spitballing but your your longevity endurance athletes unless they're doing some element of strength training, oftentimes they end up their body habitus changes to basically store fat in weird different ways. They don't really lose weight anymore. And you're, in some instances, your long term runners and your long term marathon bikers, they end up having fat deposits cardiac disease and different things like that because you're under a constant level of stress without the peaks and valleys that from normal exercise that we get.That is a yeah, so that's going to be a whole separate discussion of how do you the hormetic effect meaning your body adapting to it. Right. I think the problem is when you say go exercise people go they get on elliptical, they get on a bike, they're on their apps, their Facebook, they're reading I mean I hardly ever seen anybody read a book anymore. I remember I used to years ago people bring books and set them on there. So your body adapts to whatever you're doing. Sure. There's no shock...any type of you're not causing the hormetic effect the hormetic effect is I need you to be under stress and your body will adapt to it. That's what weightlifting is. That's what sauna is. That's what cold therapy is. That's what a lot of these different things that's what polyphenols do polyphenols create a hormetic effect. Yep. They actually your body has to break them down and then as they do that, they create anti inflammatory molecules from that so the polyphenols and Atrantil do that. The CBD allows your body to adjust to that hormetic effect so that you can adapt. So if you want to beach body contrary to what all the exercise all the commercials and stuff Richard Simmons sweating to the oldies, you know, shake it off.Thighmaster?Thighmaster. I I started to doubt this when I was about two years into my Prancercise routine. And I just realized, you know what that lady in that Prancercise video. I'm not really sure that this is for me I mean she was skinny. That was cool. Yeah. If you haven't seen it just YouTube PrancerciseYeah. She's She's interesting. I didn't know whether to do that at the old Jane Fonda tapes. Yeah. I wasn't really sure.I'm all about anything. I like trying different things. And I think that's that's one of the I think that's one of the cool things about science is that you can always go back on itself. You can have medical reversals and everything. But you do remember that I did say I was on the treadmill this morning.Yeah, I do remember that.So before you run out and run up to your cardiologist and say you're a liar and all this other stuff. Really cool stuff actually happens when you exercise. It's just not for what I was looking for. I'm trying to get a beach body in like five days or six days. That's not going to happen. Let's let's be clear, there's nothing wrong with running. You just gotta of mix it up.Yeah. So as it turns out some really cool stuff happened. Number one mood let's talk about mood a lot of people talk about. I remember Rhonda Patrick was sitting there talking about how she really likes to go for runs in not even for the anything but it elevates her mood. So we do know that it helps with mood. Unfortunately, they did look at a large meta analysis. And if you're in deep clinical depression, you can't outrun your depression. So it momentarily elevates some dopamine and some serotonin. But it's temporary. So don't think that you can just say, Well, I'm going to quit taking my antidepressants go out for a jog that is not that they've definitely shown that there's probably more complex things going on with major depression, but it can elevate your mood, but some really cool science, some other deep stuff. It does appear to have tremendous effects on cardiovascular health. This all started because they looked at double decker buses in the UK. Yeah. And there's one guy that runs around and collects everybody's tickets and has to run up and do the same thing and then run back down and do the same thing. He's does this all day long, and then the other guy drives the bus. They found that usually each one person stayed doing the job. The other one did. They showed a 60% increase in cardiovascular events from the driver compared to the guy running around. Heck, yeah. So you got the same environment, you could say ah well, they're being exposed to fumes. They're being exposed to stress. No, it's the same exact day that they're doing. One guy had a 60% increase. So clearly, moving and doing things is good for cardiovascular health. So that's reason number well number one elevate mood number two, cardiovascular health. Number three, it appears to stave off dementia. Yeah. In this podcast, they were talking about a study where they looked at people, older people who were aggressively exercising and who are in pretty good shape. Those that were moderate shape and those that were sedentary, striking difference between the sedentary and the really good shape. They actually show that dementia was completely different in these people. So brain health, longevity. They also found that regular exercise seems to turn on natural killer cells, which are cells that go around and they look for early tumors. ASbnormalities. They look for abnormalities. They're like they're like the patrolmen in your body. Sure. Well, when you exercise, these guys get released from their cages and they go, we're going to go find some bad actors, when you don't exercise and you're sitting there, you got cancer cells that are starting to grow.And not only just for that, and in of its in this particular study, but second from that is your goodness gracious, HDL can actually increase with good exercise over time. Isn't that correct?Yeah. So there's all these other this particular thing was looking at the we a lot of people exercise, and they do it for their vanity. I'm saying, I'm going to start exercising more and doing more cardio, but in a way that if I want to actually improve my cardiovascular health my brain health ultimately try and prevent cancer. So as it turns out, it is a great medicine to prescribe to your patients but the media is trying to tell you to do it for a different reason. Oh yeah, yeah.That's kinda what I'm getting at. You're not going to or at least in the clinical trials, but there's a lot of people I mean I've run I've had periods where I was in what I consider myself really good shape where I was running every single morning and my total body fat was pretty low. I ached everywhere.Yeah, I imagine so.My hips ached my backs ached, backs, I got several backs.Yeah, well, I've I gave up on just the running only several years ago and I couldn't be happier. It's a it's a hard way to go to me from...I'm a so today so I'm working out a cowboy fit and I've been getting some low level light laser kind of like what we had with the Thor laser JamesJames.James Carol.The different so Thor Lasers a little bit different this one it's I'm trying to sound a little wrist injury, I want to go surfing so I need to be able to pop up on my board. YeahSo I'm trying to handle that and looking at that I'm like, okay, all of these things are all about cellular health. Everything comes down to inflammation, inflammation, everything. You exercise too much you don't give yourself a break. Constant inflammation. We see these people that do you know marathons, they have a heart attack because the inflammation keeps it up there. There's we're all learning and we're learning about the diet we just come out with this game changer. Oh, you need to be vegan over here. And we've got meat eater podcast and show over here that says now you need more meat and everything. Then we have the media saying oh, this is you need to do your shake weight to get in shape. And, you know, there's just a lot of stuff being thrown at us. I think diversity is the key to all of this. Like all things just like you said. If you only ate cauliflower it wouldn't be healthy. If you only did one type of exercise probably not that your body will adapt.Definitely. So what this tells me is, there is the media out there with all different kinds of avenues for people to explore exercise. If you have a question about a particular type of exercise, benefits, and or detriments, hit us up KBMDhealth.com. Go to the Connect with us section, shoot us an email and we'll start addressing it here on on the show.Right on and then I want to start getting a bunch of experts over here. I want to get Gabrielle Lyon, Dr. Gabrielle Lyon. Talk about proteinsI think there's an S on the end of thatIs there an S? I think so. L-Y-O-N-S. We'll figure it out before she comes off. Yeah, well. We'll definitely check.Let's see if we can hit up that Prancercise woman to see if she's still crushing it.I don't think she's gonna make it.Jane Fonda's not coming either.Oh my goodness. So what do we learn today, man?Man, I learned that you gotta be careful about the way you exercise it. Tony Yuns got a great book out as well as Jason Harris. Playing God by Dr. Anthony Yun, MD. The world's or America's holistic plastic surgeon. And then Jason Harris...One more plug for Anthony. He's just a cool guy. YeahLike when you read this book, I really felt like I was talking to him. YeahIt was written and I know that he wrote it with Alan eyes and stock and helped him write his first book the Age fix. Which I have that one, but this was a really nice fun read. So I encourage everyone to get that Playing God. Go to Atrantil.com take a look at Atrantil. That's our baby right there helping there with the polyphenols. Getting rid of bloating. I mean, nothing is out there fixing people's bloating and we got something we got lightning in a bottle. Have you seen that Key and Peele skit about lightning in a bottle? No. It's really funny. Get out, basically, Key, I get them always backwards. He's talking to him. He goes, hey, man, we need to do an app. And he goes, yeah, just a lot of apps out there, but whatever. And he goes, like an app that people buy and they get more and he goes, yeah, but what you're describing is lightning in a bottle. And he is like, oh, I got that. But no, but I mean, it's just it's just a saying it's just it's just a phrase. He's like, no, I mean, I got that. He's got lightning in a bottle. No i haven't sen that. It's really funny because then it just kind of goes on and on it goes, because this is not he's like we can we can make a lot of money off this. This would be like, this would be like the goose that lays the golden egg. He's like, Oh, you mean honkers?Of course, you have a goose that lays the golden egg.So who else we have Jason Harris's Soulful Art of Persuasion.Yeah, but yeah, but I want to do a full review on that one because that one is super deep.We'll do that soon.Yeah, he's got he, I mean very clearly he's, he's been a really good person because he's got a lot of friends that back him up Tim Ferriss, Ryan Holliday, some people that I really respect, read a lot of their books. And, and you know what's really fun I like opening a book I just forgot how much I enjoy sitting down, doing some charts, having a cup of coffee, I'm trying to get into my routine. One of the things that that most successful people do is that they have a morning routine. And I'm going to start making this part of my morning routine, just read X number of pages from a from an actual book hardcover.It's a lot easier on your eyes than the screen. No doubt good. Dude I'm not gonna blow an eye hole doing that. No, no, no valsalva retinopathy here. Getting all the way through that. Hey, last but not least KBMDhealth.com. By the time you're listening to this podcast, we got a real processor.Oh my goodness, that means that we're gonna we're gonna pass on our frustration and the fact that we've had have been so patient, so we're just going to celebrate, it's going to be like confetti, just CBD bottles falling out of the sky...There's roughly 1000 of yo

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Dr. Marisol, The Queen of the Thrones

Optimize Paleo by Paleovalley

Play Episode Listen Later Nov 14, 2019 86:59

All right.This is super exciting. We have the 22nd episode of the gut check project. And, unfortunately, my co host Eric Rieger is actually at a conference right now. But we have a huge upgrade. We have Dr. Marisol naturopathic doctor, who is now my co host, and my lead guest both, which is awesome. So, this is going to be a super super, super fun show because what we have going on is Dr. Marisol. We're going to talk about pooping. We're going to talk about castor oil. We're gonna talk about bowel habits. I'm just a simple country, butt doctor, she's a brilliant naturopath. So we're going to welcome Dr. Marisol. Oh you're awesome. Ken thanks so much. You're so so so so humble. It's amazing but I have to say you're pretty incredible gi specialist honestly.That is thank you very much but I'm just I'm just thrilled to actually have a different co host so we're gonna let we're just gonna bounce off each other we're gonna let and let everything roll here.You're just happy it's a cuter co-host.Eric's extremely attractive. If he'd shave i think that i think we'd have a more of a connection but he just won't do that. I know. I know he could do that whole Mr. America contest. I'm telling you. I keep telling him to go in it. I love that Dallas accent.Before we even jump in I just want to ask one one question Yeah. How you pooping?How am i pooping? I'm pooping like a champ. Actually, I'm pooping like a queen. Right?So sure her moniker is that she is the queen of Thrones which is why, now it's not just because you're here. That's actually how I introduce everyone, as I just asked him how you pooping? I love it. And I'll go to family reunions and just walk up and say hey, how you pooping?You know, that is the most important question that we should be asking people, honestly, or at least asking ourselves every day, right? How am I pooping? Because it's so important. It's like your number, you know, they get I always say, you know, poor poor poo, you know, it has a bad job where it you know, got the number two label right? Like, why is it not the number one like, in my opinion, poo is number one, not number two, the most important thing that comes out of your body And you know, this was completely planned, but this is Episode two two and we've got the queen of number two. I love it.This is awesome. You know, synchronicity at its best. I'm telling ya. Yeah, that's an important question. Honestly. That's what that's what I've been asking myself for the past, gosh, 40 years of my life. Right?So you did this in utero? You're asking questions. Oh, you're so sweet. No, no, I'm definitely over forty. But because I poop well, I do look younger and better and I feel better than I did otherwise. Right? And when I was younger I really suffered with digestive problems like constipation. My mother was constipated constantly. You know, my father had IBS it was we were just a bunch of problems in the butt. Tt was just gosh, everyone always a bathroom occupied. We only had one bathroom in those days.At home was in Ontario Canada?Yeah, Ontario, Canada, right back up northern Canada. So we were isolated in the very north in the mining towns. Oh, my goodness. Very interesting experience growing up there.Lots of family members coming out of the bathroom going, Oh, that didn't go well ay?That's right. So for us, you know, that conversation was very, very open. We would talk about it at the kitchen table, we would talk about it everywhere. And then I would remember going to a friend's house. And then I started talking about it or say something to a friend of mine and they'd be like, Oh my God, you're so weird. Why are you talking about poo? And I'm like, I don't know it's interesting, and it's what we talked about. Right? There was a common converstation at our home. It was really it was really interesting. And I keep on you know, what really changed my life though was Oprah and Dr. Oz. Ironically, the the that show they opened, I think Dr. Oz was just going on The Oprah show for a couple of episodes. And he went on in one of his first episodes. And what he did was a huge explanation about what you're poo is saying about you. And that day when I watched that episode, something in my heart lit up. And I was just looking at him like a child in the candy store, like I just was amazed by what he was talking about, and how there was actually things you could find out about your body from your poop, and it just set me on this trajectory on this pathway to really always constantly be looking and investigating my poo and because I suffered with IBS, with so much digestive problems up until I was in my 30s when I finally you know, figured out my formula to fix it. I was looking and learning from my poo, so it was just it's just It's been a really cool ride to get me to becoming the queen of the thrones and what I'm doing now. And the ride on the throne that is.Let me ask you, so when you watch this episode with Dr. Oz, were you a naturopathic doctor at the time? No. Oh my gosh, this is talk to that we're talking like 19 I think it could be like 1992 maybe earlier like I was around 11. It was it was early on in my life. Like it was a point, a foundational point in my life where that something just inside me clicked. It was like, I want to talk about poop that seems really important to me. What were you doing at that time?So at that time, I was a young young kid I was in dancing in my dreams were to become a Liza Minnelli and a doctor. I wanted to be both of those things. My Liza Minnelli dreams got crushed by a dance teacher who said I didn't fit quite in.Uh huh. Right? Which you know was now I look at that as the best gift I could have given been given in my lifetime. Because if I fit in, I would not be here talking about poo, let's face it because it was taboo. Righ?t And so what I wanted to go into was, was being a doctor.Really?Yeah, yeah. And so that was, was that the motive to get you to start studying naturopathic medicine?100% Oh, because I suffered my entire life suffering suffering and you know, your purpose is within your pain 100% of the time, when you you know, you're dealing with something, you're trying to figure out how to make it better. And you and like someone like me, like I I, I'm always looking how to advanced, how to be better, how to improve, and I couldn't get this part of my life improved, because IBS can be a huge beast, you know, because it's not just only what's going on in the digestive tract it's so much more. So I really needed to look at all those things, and I needed I think I needed to take it into my own hands and take it and that's why that's what eventually led me into naturopathic school.Oh, that's awesome. So I'm really blessed. I mean, I think that one of the most common things is that when people in other fields of medicine and I think there's so many naturopathic doctors that really focused on the gut because they realize how important it is. Yeah, I mean, I'm a little bit bias because I'm a gastroenterologist. I say that all health begins and ends in the gut. But it really is because what I see in my clinic and I'm sure it's exactly what you see, you can't get away from it. If you have a sore knee, you quit running. You go to an orthopedic, whatever, you get a surgery, something like that. But when you have intestinal issues, it's always there. So. Yeah. Always. Yeah, it's always there and it permeates your entire life. You're constantly dealing with it constantly thinking about it. Like I'm still in the habit of when I turned in my 20s my IBS shifted from a constipation more to a diarrhea and I'd have periods of constipation, but it was predominantly like explosive I don't know when it's coming diarrhea. I love this. I've never been able to talk so openly about this. You know, like, I'm just like, this is my love my story.So I want to get into your I want to get more into you as the person. Yeah. You in the history. But I want to tell you that you may not even remember this.Yeah, eah, yeah. So I met you a couple years ago at mindshare. Yeah. And we were sitting around talking.Oh i remember. I myself am gluten intolerant to me a long time. Trying to figure it out. So you know, we developed Oh, little bit of housekeeping totally forgot. This episode's been brought to you by Atrantil. Go to lovemytummy.com/spoony or go to lovemytummy.com for a discount code. I forget that my our own product is sponsoring the show. So sorry Chuck. So I did not realize I was gluten intolerant. Yeah. Until the person that helped me develop this,Brandi, who's my research manager, we diagnosed her with celiac disease. So I would go out to lunch during work and I would I would eat gluten free sort of to support...The people. And it took me a long time to realize that I would not have to rush back to the office because I'd have to use the restroom. Before I'd start seeing people again and she pointed that out. And I was talking to you. I was like, yeah, it took me forever. I would go out on a run and be like a mile out. And then you have this urge to go. You don't know if you should stop and waddle bad or whatever, and that's when...Or squat.And then you told me a really funny story that if you're cool with sharing I'd like you to share?Yeah, well, gosh, I have so many funny stories like that. Are you talking about my Dominican Republic story probably the one on the bus?The only one that you told me. No, it's one that you had a route and that you would actually squat in somebody's yard. Oh, yes. That's Oh, yeah. Oh, yeah. Yeah. Cuz I mean, I have a around my house, I have a pond. And you know, it would be that it would be explosive, right? I'd be like, suddenly, Oh, my gosh, what's happening? And so I literally have squated in people's lawns and their back lawns, thank God because it's going heading in butt. You know, like when nature calls, you know, nature calls and when, when, when she's calling in that way. It's not. It's not always a call that you love or really want to answer, but you got to do something about it. And you know what I like to this point, now in my life, it's so funny and I'm re patterning this, so up until now. I would always look and see where the bathroom is, wherever I go. Because of that, right? Because there's been so many times that I've had accidents or what have you like when you're suffering I realized you just don't know when it's going to come and it's it's a can be a scary thing to live with. We probably share very similar patients and when that the trauma that can happen I mean I have stewardesses,pilots, people that are trapped in a, you know, here in Dallas there's commuters and the thought of that just the anxiety of that can actually trigger something. Exactly it makes it worse and you know, you know how you say like the gut is it all and then begins with the gut. I agree. 100% like, you can't like digestion is how you are digesting your life. Like there is no other way around it like if things are not good in your life emotionally and hence the anxieties triggering an IBS like an explosive diarrhea. Like emotionally physically what have you. It all has started in the gut,all of it. So my research in you know, I do a lot of irritable bowel do a lot of inflammatory bowel disease. And we got really into I was one of the first doctors that really started embracing worked with Dr. Mark Pimentel when he was I was one of the people that on this study for Xifaxan and things like that and so I was hearing about bacteria, the microbiome like 10 years before everybody else was and now it's really interesting because even my own colleagues still aren't addressing that but the naturopathic world embraced it early on.Oh yeah, we're all about the bugs and bacteria right? Because we're all about the ecology and how the body is a system right? In conventional medicine. I mean, I love you guys thank God for you guys thank God for conventional medicine. You know what we all benefit from it the the but you you tend to look at it as like one organ system, right? So but we look at it as our as it as like a garden like we're a garden, right? And in the garden, you need things like water, you need nutrients, there's bacteria in the soil. So for us, it wasn't a large stretch to think oh, wow, we should be using like probiotics in our prescriptions because guess what, it's a garden for us. So just like already our methodology about how we think about the human body, and how like in naturopathic medicine, there really aren't specialists. Really we're all generalists, but we just have a focus on certain areas, like some patients, some doctors and naturopathic doctors might have a focus on you know cancer care you know I have a focus on gi just like you so the majority of my patients I see a lot of IBS Crohn's colitis, but I tend to also see things like autoimmune conditions and cancer but you know what I treat them all very similar really because I still start with the gut on everybody.So you watch this Dr. Oz episode? Yeah. Tell me about your history. Like when does one become a naturopathic doctor? What did you do? Just give me the give me the history of the queen of thrones. Oh, gosh, so so this is the thing so I watched Oprah Dr. Oz I was in a time of my life. I was rounder you know, I was I was, you know, isolated from society, like not society. But from, you know, kids kids didn't like me. I was the strange little Spanish girl who brought sardine sandwiches. It didn't smell good you know?We know. So. Up in, you know, that was my life back then and... Were you born in Canada? I was born in Canada. Yep. So my father's from Spain and my mother's from South America. Where in South America? Uruguay. Okay.Beautiful, beautiful country like it's...Se habla espanol? Se hablo espanol. I'm always trying to get my teenage kids to speak Spanish because you know, it's such a gift to be able to speak Spanish, I've got my he's soon to be 15 year old, I got my 15 year old who is will only speak Spanish at the house. And there are times I'm like So that's, you know, that's good though. That's good because, you know, Spanish opens up doors in so many different ways. And you know, like I love coming to this in Canada, where I'm at, I don't run into too many Latinos, but when I'm in the States, especially Dallas, and you know, like the more southern states, it's awesome. I love it because I'm constantly speaking Spanish. It's just like, this is great. I want to move to America. I love the states.I would say that my, my Spanish really took off when I was in training in San Antonio. Yeah. Almost every patient i saw...And you know what I see patients because of the languages that I speak. Many of them come and search me out. It's super cool, but back to my story. What had happened was that I you know, I wasn't living a happy life as a kid. I was, you know, isolated from the crowd and I was also very anxious, right, anxiety was a huge predominant factor because of my isolation from the group, you know, I was I was a different kid. And so I was but I got diagnosed with asthma instead of anxiety. And so the medical system kind of failed me when I was younger. And unfortunately it put me on a series of lots of drugs lots of prednisone, which made me go from a you know, a plump cute to a very overweight teenager and itWhy were you on prednisone?Cuz was I was having such anxiety and but it would manifest and look like an asthma attack. But the doctor never even examined my lungs he never he never did a physical exam What?!There was no oh no yeah, this is back in the day. Yeah, nothing was done. So you can imagine my what I thought of the conventional medical system and family medical doctors at that point in time, right I didn't really have very cause here I was, like, you know, medicating with prednisone to reduce my asthma attacks, which I wasn't really every having them it was all anxiety. So I was I was I was the case I was really mismanaged and it is made me gain more weight isolated me more my anxiety got worse as I got fortunately my mom got to the point where she's like you know what i'm done with you taking these drugs and she just pulled me off of them. How old were you when this?I think by that time I was around 15-16 so I remember going into high school and still being a bit overweight and then once appropriate the prednisone was gone. My weight started to go down.And it's not just that it's not just the weight but the acne the inability to sleep that's a horrible drug. It's a tough drug it was a tough drug to be on as a. I was, the acne didn't affect me. Definitely sleep was a problem. Like so lots of my systems weren't working very well. Right like I like it. My body definitely wasn't happy. I like it. I like stories like this because it shows you know you said that your pain is you know, your your pain point ends up becoming your your purpose. Yeah. And for anybody that's ever had a child, that's 15 and unhappy and anxious Gosh, it's so hard.You know, and then to see you take that and then become really this incredible brand where you really put yourself out there if anybody gets a chance look at her YouTube channel. There's videos of her on the toilet talking. It's really funny.It's awesome. I love it and I get to be my Liza Minnelli right? Because I get to do it but my own way talking about poo. It's so perfect!So you're 15 you're going into high school, you finally get pulled off the drugs? What happened? Yeah, well, then then my life just suddenly becomes much better, right? But my anxiety is still there because that's still not really being managed. And, you know, so but I do lose weight, I'm looking better and being accepted more, which is great when you're in high school, you know, I still have a lot of confidence issues, of course, because you know, you spend the greater majority of your life at that time, you know, being unconfident, unhappy with who you are anxious, you know, it's not not a nice nice, not a nice life. And then you know, someone tells me to go into a beauty pageant. So this is where I've got the queen. And this is actually what helps to build me It builds me up. So I you know, entered it in the hopes of I didn't think I would win it because I didn't think about myself. as attractive or anything or that I didn't like up until then I didn't believe it right I didn't believe that I could achieve anything like that. I but I could achieve the talent because I was very talented I played the piano and I danced. So I went into the competition and and I won the talent and I oh no I didn't win the talent I won Miss Congeniality, which was like awesome to me sounds like at least I want something. How do you win the Miss Congeniality part?You're just really pleasant and nice person like I am i guess.You know what? I'm going to say if this was a Canadian beauty pageant where everybody's pleasant and nice. Winning Miss Congeniality is a serious deal.That's right? Oh, that's a really awesome way of thinking about it. I need to think about it more that way. That's wonderful.Yeah, I mean, like you would almost think like in other Yeah. Like if you're not I don't want to single out a certain part of the United States. Yeah, certain parts all you gotta do is just be like, say, hey, and you won.That's so awesome.Instead of flipping somebody off.There you go, but it what ended up happening is I actually won it and and me winning it. It was first time I became a queen, and it's one of the reasons why my brand is also called the queen of the thrones is that it just it just built my confidence. So I just needed that one little vote of somebody else seeing the magic that I had inside of me. So that really changed my mindset changed how I was working and expressing myself as a person out here in this world. So that was really cool. And then, you know, took me through travels, I started doing more pageants, more, more, more, more of that and, and then it came time to go into high school into university and I, my mother was like, go be the doctor, go be the doctor. And I was like, I'm not being the doctor. I don't want to be a doctor. Look what happened to me. I was taking prednisone and I was like, 180 pounds by the time I was like, you know, 13 like that. No, I don't want to, I don't I'm not going to go become a doctor and do that to anybody. Because that's what my that's what my paradigm was. I looked at medical doctors at the time, that they didn't help you that they they they just gave you drugs that weren't good for you. And a lot of people think this, you know, and I still want to correct that. Because there's a time and a place for every single medicine. There's a time and a place for prednisone. You know if the patient is assessed properly? And you may need them. Right like in an acute flare up of Crohn's and colitis and you can't manage it. Prednisone would'nt you say?Oh, yeah, this is what I. Like my biggest problem is as a gastroenterologist is having people that possibly have been mismanaged for a very long time. And then they come in and they've got osteopenia, and they're 30 years old and they've got all these other issues they're morbidly obese they've been on and off prednisone and other options have not been discussed. So the way that I view prednisone is is exactly that. It's a very powerful drug, but you only want to be on it twice in your disease course. Once to see if you go into remission the next one to say okay, now the we pull you off for the second time. What are we going to put you on so that you don't have to back?Yeah, yeah, see and that's that's that's that's a great doctor. And and that's that's what there are so many great doctors out there. Right? It's like any profession, right? Like there's, you know, great naturopaths and there's not so great naturopaths and there's great doctors and not so great doctors. There's great lawyers and I don't know if that works. Like, no, I know really good lawyers, like I love my lawyer. So, you know, like, they're in all professions, it's like that. So you just have to search and find the one that really resonates with you and just just you need to listen for these key things, right? Like a doctor who is saying these things to you, like, you know, we'll try prednisone, but that's a dangerous drug. Like it's not something that should you should be on, managed for years. Like I was on it for years. So I ended up instead going into languages and business. So that was where my school ended up taking me. Really?Yeah. Because one thing I knew that I loved talking, and I loved people, and I figured, you know, one of the greatest platform to do that would be business. And so that led me there. And then I ended up going into actually my first very first job coming out of school was it was completely aligned in the stars was to work for a homeopathic pharmaceutical company from Germany called Heel Called Heel? Heel. Hiel? Heel. Heel. And they are an unbelievable force in natural medicine they created this product called Traumeel it's no longer available in the United States they pulled out. But it was available and people out there will understand what if they've ever been in the natural world they've heard of Traumeel, an excellent anti inflammatory actually works very similar to a prednisone, but natural. It's an incredible thing. And there's no side effects to it. So in Germany it's number one.Yeah, so one of the things like we would as we're launching Atrantil in the EU and stuff, oh, my goodness, though, so we, we have our own. We got recognized in Canada. So we have our own...That's great. GoodNPI number, whatever it is that you guys do.NPN. Natural product number. Yeah.So we got our own NPN. And then we were not expecting the added expense of having to translate everything into French.Oh, yes.So that one was that was one of those non budgeted type things. So we're in Canada now. We're bilingual. But dang those Germans. They are strict.Oh, yes. Oh yeah, they're quality control. Everything is just phenomenal. And that's great. I think that's fantastic. I think anything that we do in our life, if it's worth doing is worth doing with excellence, you know, and and I loved working for that company. I was so fortunate, you know, I was able to train with the best, the best doctors in Europe and Germany and Belgium, you know, sports, medical doctors, like gastroenterologists. It was just awesome. Like, I got the opportunity to see the world from so many different places around the world.Where did you travel with that company?how old are you when you're doing all this? So I would go to Germany, I'd go to the United States, South America, it was just, it was just everywhere. Those are the main main places, but it was it was phenomenal. Like what an experience, but what it did is it introduced me to other practitioners. So that's where I got my first flavor of what a naturopathic doctor was, and a chiropractor, and then it opened up a whole new world to me of a different form of medicine. You know, a medicine that was inclusive, that really focused on from what I knew, really focused on assessing the patient, right because we know up until where we're at only what we have had experience in our lives. And my experience with the medical system was was one of not being well managed, you know, because even then later on in my, in my teenage or sorry, adult years when I started going to things like birth control, you know, I wasn't well advised on birth control and I, you know, went on a different pathway for that. So, so many so many issues there, right, like I was given Depo-Provera, and Depo-Provera just actually aggravated a lot of my digestive symptoms. It also made me bloat on certain points of time, you know, my period was messed up when I went off of it. So, you know, that was my perception of medical system. But then when I saw naturopaths and chiropractors I go, hey, there's different ways to do things. And there always is, right? I'm about 26 or 27. I'm about 26 or 27. And then I finally like, just something inside me when am I I was back up in my hometown I was as that sales rep. I was speaking to a doctor when my good good doctor clients, and I was teaching him and training him all the methodology of what Heel taught which was something called homo toxicology, the study of toxins within the human system. So it's so phenomenal. It talks about the you know, how disease becomes manifests and how it reverses. And how, you know, first signs of disease are things like discomfort or, or, or discharge, right? Like if in our world, it would be like mucus and our stools are diarrhea. And then after that, it becomes inflammation. And it's just like the different steps of the pathology of how you know how disease manifests and how to reverse it. It was super phenomenally interesting.That's really cool. I mean it's basically all in, in my opinion, all of disease really comes down to inflammation. If we can stop the inflammatory process, we can stop cells from being damaged and blah, blah, blah, blah. So...I'm gonna add I'm an add in stress. Because I think to me, it's like a two a two prong thing. I think people will have like, it'll either be the like, you know, chicken or the egg. It's they'll start with the stress and then the inflammation comes about or the inflammation starts and then they have more stress. So then it's just like, and then it's you know that snowball effect down the hill but that big snowball is becoming bigger and bigger and bigger. Have you ever seen a snowball living in Dallas?A snowball. It's...soBasically two snowflakes will fall a year and there will be like 700 accidentsOh that's so funny oh my gosh That's very it'll it'll snow like once a year just kind of dusting and everything will just shut down. Everything will shut down. It's just like disaster mode.So funny. Yeah but it's so it inflammation and stress are really really key. And you know, like if I look at myself and even just my history like that, that anxiety I was dealing with was full on stress like that was of course messing up my digestive tract, right it was making making my digestion feel totally off.So I... Trying to move your mic here so that we can get a little better picture of the queen of thrones here. So you know, this the whole studios in an adjustment you know this is two two but everybody wants to see the Beautiful, Dr. Queen of Thrones here so there we go.But yeah, so so it was a great introduction and what an amazing methodology to learn. So I was training at that point, naturopathic doctors who are top in their class, treating cancer, a G like GI focused doctors, it was awesome. And what ended up happening is this doctor in my hometown said to me, he goes, What are you doing being the sales rep, what are you doing? He's like, you need to go be the doctor. You need to go be the doctor. And again, it was one of those foundational points in my life, you know, someone believes in you, and it's just enough, you know, gas in that engine to make you go phoom right, just jump on. So and I you know, when when I get an idea, and when he when he planted that idea in my mind, that was it. I was like, I literally called the company the next day and said I was quitting.Oh my. You don't play around.I don't play around. You know, when I know it feels right. It feels right. And that felt right. I just I knew it 100%. So what I what I did is the company actually wouldn't let me go that fast. So they actually prepared my journey to meet more doctors and really made it great. So then I went to naturopathic school at 28. But I didn't have my sciences because I had done a business degree. So I actually had to like read get all my sciences done. So you know, when you go back to school after you've been working, making money, you know, and you have to you have these big mountains you have to succumb to right, like, I literally had like Everest, I had to go back and do my basic sciences. I had a lot to do, right? Luckily, there was ways I could do it faster and get my basic sciences and I did that. And I started school and I loved it. I was just like, this is where I need to be. I had to really focus on the sciences and get really in depth those first few years because they were a little bit more challenging because I didn't have you know, all the years of the science background that that that other people did. And I went in as a mature student, but it was an amazing and amazing experience.Had school always been easy for you? No, no, no. And you know why? So let me explain this. I am brilliant and I don't I say that in the most humble way, I'm my, my superpower is really to be able to grab things, complex, complex ideas and simplify them. So I'm very fortunate in that way. But because I didn't have confidence in myself, because of all my experiences as a child and what was happening, I wasn't excelling in school at all. And I don't think that the school system was meant for my mind and how my mind works. You know, like I if if a concept if a simple concept is skipped through, and it jumps to the advanced concept without going through the basics, I get lost. So there was many times in like math class or such, like fractions, I couldn't get my mind into fractions. I couldn't understand the concept of it, right. And so they jumped to the next step, and then I would be lost and my marks would would, would be that way. So I had to work hard. So going back to school would have been somewhat stressful for you. Very, very. I mean, just the idea that I'm gonna quit this job. I'm gonna go back to school and I'm going to revisit a lot of my insecurities. That's impressive.Yeah. And, you know, to the and thank you for that. That means a lot. The the impetus also to go back to school was also that I was like, you know what I had been to see a lot of naturopaths and I had been to see a lot of doctors. And you know, my gi specialist at the time was like, I'm sorry about your luck. There's nothing you can do. And I'm like, Okay, well, thanks. I'm like, that's not you know, that's not the answer I want but another, you know, another mismanagement.Yeah, the one that I mean, I always joke around that everybody, all the patients that come to see me and I'm sure you had this also, which is, you go to the doctor, you wake up from your endoscopy colonoscopy, and they're like, great news. It's all normal. You just have IBS.And then you walk out and you're like I still feel like shit, exactly. What does that mean? Now I just have a label.Exactly. And you know, even with an naturpaths I had seen before going back naturopathic school, they had none of them had tested my food sensitivities, and they just put me on these diets, for my food intolerances. They just put me on these diets that actually made me feel worse. So I kept on like losing confidence in the entire system. And I was like, well, maybe I can go back and become a naturopath and I can figure it out for me, right because I was that determined because I'm like, there has to be a better way to live. There really has to be a better way to live. And you know, and of course you know, go back into school it was challenging because I wasn't an excellent student, but I did become that but it did aggravate all my IBS symptoms. So during school I was I was a mess again, right and I had to work through it. I had to walk through it and try my best. And then finally someone tested my food intolerances and my sensitivities. And the thing was this is that all the naturopathic and cleansing diets before that time, were all based on rice and almonds and you know, you would take away the gluten and take away the dairy but you'd still be eating the grains like the rice and one of my big I'm Spanish background, you know, guess what I've been exposed to the majority of my of my life, you know, my gut is constantly being exposed to piyaya, maybe and piyaya is made out of rice, and I have a very permeable gut because I'm suffering with IBS my whole life. So what, what what food molecule is going to be elevated?And then of course the South American component where you can add a bunch of beans to it so.Yep, love those beans do exactly right. I love me some piyaya. Oh man, I love me piyaya too. But the thing was I had to I had to be stay away from rice for a period of time because I was just over consuming it and it had become an intolerance to me my body was overreacting to it. And that's like, That's awesome, right that I was able to figure that out through school. So that was one of the components. Super like good great experience. I've been really, really blessed in my life I'm so thankful for.It's really cool and I like hearing the background stories of somebody like you because you've over although you've you've been able to make changes, you make adjustments you pivot, and then you make this life change. And then you revisit some of these insecurities, which only makes you stronger. Yeah. And only allows you to continue to grow as a person. So then, you get into naturopathic school. What was that like?Yeah, so it was a total shit show. I'm not sure if I could say that word on here but...Ya no, this show you can basically say anything you want.Oh, fantastic. I've been really like, you know, trying to be very prim and proper here but I really wanted to bring out my bad ass.When we were on the spoony network or when we're still on the Spoony network, oh that's the label to Spoony right there.Oh awesome.Shout out to Ron and all those guys but it was pretty fun and because I was concerned about that also you want to like be normal and everything and so they're like look in our world just do not say GD or the F word and basically everything else is okay.Cuz I say shit a lot. Patients say shit a lot to me.Of course they do you know my my first book coming out in the in the spring is called Oh shit. I saw that. I cannot wait. Yeah. That is really cool. But you know why I labeled it oh shit because I was I used to say when I would be ready to about to have an accident. I'd be like, Oh shit. Like, and if you look at us, what we do is when we have a moment of anxiety, what do we say? Oh shit. Oh shit, right. So that's the whole energy of it. So the book is gonna be really great. I'm super excited for it, but I'm back in school so I'm in school...Just to clarify so that I saw that the title of the book is doesn't actually say shit you do the...Yes I do the little star I do I do. I'm keeping it clean. You know, the reality is is that like Northern Ontario you swear a lot like I grew up in Northern Ontario. Like lots of truckers like we said, I don't want to stereotype anybody but I just grew up in a place where I learned to swear a lot right so and the majority of the words I would swear with shit typically so that and you know, and I like I like saying like I'm a badass because I am a badass. You know, but it's it's uh, yeah, I gotta keep it clean you know, got it gotta do those things.So right now we're in a shit show. Yeah. Which we're just kind of bounce around so I love a I've got a little add Yeah, like bouncing around. So we just went forward in time we got a book coming out. We'll talk about that. But now you're at the shit show called naturopathic school or are you going into graduate school?Yeah, I mean, the school is phenomenal. Like the knowledge and education you learn is great, but you know what the volume is a lot. Because like, it's like we're talking like we not only have to learn everything that conventional doctors learn, we also then have to learn what naturopathic doctors learn. So the amount of material that we have to go through is incredible unless you're constantly being I mean, I'm sure medical school also is very stressful. And it takes it takes a bit of life out of you, you know, but which you regain amazingly, afterwards. But it was a lot, a lot to learn a lot to learn at once. And so and because and because I had been in the past challenged in my learning, I would invest a lot more time than the average person would. So I was taking it to that next level, because I really did. You know, when you go back, a lot of the people in my program were younger, you know, they hadn't lived, they hadn't worked. And, you know, a lot of them just cared about getting good grades on their exams. And you know, the typical mentality of students. Well, it's a typical mentality of a graduate for sure, cuz they worked that hard to get where they're at. And then all of a sudden they're amongst everybody else. So like in medical school, at least in medical school, I went to, everybody was at the top of the class when they came from undergrad, and all of a sudden to be the top of the class there. It's, it's an ego blow. And a lot of people just view it as a badge. Like, I'm just gonna learn this and crush this and do whatever, but to actually realize no, I'm learning stuff to apply to people later on, is hard to do.And then like, I remember there was one girl who was like in a we're in a class and she's like, lifting her hand. She's like, Can we just like know, like, what topics you are actually going to be testing? And I like actually flicked her in the head. She was say me, I never because I was like, I looked her and she turned around, she's like, I go, I go, you are going to be a doctor, taking care of people's lives. That is a huge responsibility. And if they're not going to come in with just what you learned on the test, like honey, you I could do that because I was an older mature student, right? She was younger, and we were friends and you know, and she and she loved me so I got away with it. But you know, I said to her, I go, you know, you have a it's an enormous responsibility to be a doctor and you know, I feel so honored and blessed and like you do to Ken I know because we've had so many conversations like this.That is I want to not to digress from this at all, but this is a great opportunity. I got our good friend, Tony. Just came out with his book and your book, I can't wait to read your book. But Tony's awesome. Tony's awesome love this guy, this whole book. It's called playing God, but it's basically exactly what you're talking about. And he brings up an example in there, where there's this star resident, the star resident that's kind of competing with him about this plastic surgery. But Tony got they went and took a test. And he did well on it. And then there was like medical emergency the next day, and he figured something out that and he said the patient's life, and the other resident didn't like it, like How'd you know how to do that? He's like, well, it was on the test, but it's all about studying to apply.Exactly. Yeah. Yeah. Studying to apply. And It's so important, right? So I would definitely spend like, prob I would say like my 82 Gosh, probably 120 hours I would be I would be studying or in school. So it was intense. And you know, I really I unfortunately really hurt myself in in in that that time and by the time I got to third year moving into my fourth my fourth my residency year, I actually I felt completely ill like chronic fatigue. I couldn't get out of bed I couldn't I couldn't do anything. I was just I was really really stuck. Really? Yeah. And and at that time, which was scary was that I was actually doing all the right things. I was eating all the right diets for me, I was taking all the right supplements I was you know, doing all the right things that I could do. And I you know, had a really heartfelt conversation with my lovely mother, who you know, normally was one who just constantly pushed me forward, push, push, push, push, push, but this was the time in my life where she said, uou know what, it's time for you to rest and take the time that you need, so you can get back to being you. I thought she was gonna put you back on prednisoneNo, no, thank God. No, my mom my mom was always trying to get me on to witches brew right it was like she was she already have that latin American you know, let's do like the natural I got some herb.No I would like I said when I was studying in San Antonio not uncommonly the whole you know, the whole chicken eggs under the bed kind of thing and whatever.Absolutely raised part of our culture and our tradition is so awesome but and you know what and I did that and but more more importantly than that what I did was this there had been something that was recommended to me at every health food store I had gone to as a sales rep for that natural company, every naturopathic doctors office, every chiropractor I had talked to every every person I had been in contact with with something called the castor oil pack. And I had said no that I wasn't going to do it for the longest time probably about 15 years at that point. Because it was messy I felt like it was too much time it was a hassle didn't make sense to me. I'm like how can this thing that's like you pour castor oil, you know, which is you know what, you know, people that live in the Caribbean people are like oh god don't give me castor oil because they you know take it weekly to you know purge so that they prevent their parasites right this kind of like cultural tradition. I didn't know that. Caribbean islands? Yeah, Caribbean Indian Indian culture as well too. They do that weekly one tablespoon castor oil to purge the gut. Right. So So I was thinking like, I don't want to do that like because I had a misconception of it and how is castor oil put on your body topically gonna go in your body? And how is that going to work and help my gut and you know, just miraculously improve my IBS, right? I'm like, whatever. I didn't believe it. That was my like, cuz I was also you know, my sister's a dentist. So I also have that mindset where it's like, you know, I am very, very, very scientific and I am and the woo woo's. I'm into both of them. I don't want to call naturopath a woo woo but you know, that yeah, I mean, it is it's like, you know, Earth medicine and like the herbs and then the homeopathy and all these different things like just different tools, mindset. These are all different tools, and I think they just were I think they work so good together with Science and these tools are now like natural things are also getting a little bit more science behind them which is excellent and and experience helps too but I had to figure out something different I needed to do something different so then what I said to myself was this you know what? I am going to try that that castor oil pack I don't care if it's a shitty mess whatever I'm going to do it I'm going to try it and I'm going to see if it's going to help me.Now wait a minute. What were your symptoms that you were experiencing at this time? Well, it was it was severe chronic fatigue including like constipation alternating with diarrhea so I had mono antibodies so I was you know and and and stress honestly like I think to me I think the really the biggest problem was just that it was stress like that the stress was just so enormous and then I was putting so much pressure on myself to be the best that I could be so that I could be the best doctor because I wanted to be no I need no I'm I needed to be the best doctor ever because this was super important to me because of what happened to me as child.So what I like getting the history of this and I like listening to your struggle because people don't see that and what they do is they'll go on your YouTube video and say, Oh, she's got it all together.She's so amazing, perfect.Yeah, and people don't realize that you you had kind of a difficult childhood you turn around and then in your quest to become a really good doctor you destroyed yourself. People don't realize that that's the kind of effort that's the kind of mentality it takes to become the queen of Thrones. And all people see is this end product.Yeah exactly. You know what we are one of those this quote this weekend one of my friends said, it's like you know, people see in the one minute of success what people have been doing behind the scenes for like 10 years, right or from in anyone's case it's like their lifetime before that like everything that is created who they are up until this moment right now.There's a saying in the entrepreneur world it only it only took 10 years to be an overnight success. That's right, exactly that right like and that's the thing is that you know, it's like every like everything I look at my life, everything that every journey every every every shitty point, you know those things shitty points are so bad. And now I guess, I'm so happy I swear this is like awesome. A whole new.You know, all those points, they're all part of your journey and it's so important you have to honor them. Do you have a favorite spanish swear word? No, because my mother wouldn't really I know my mother wouldn't really like teach us that right and so because we were in Northern Ontario there weren't too many Spanish people we never got indoctrinated with, with, you know, any of the spanish swear words. My parents were very clean. So we did. I mean, maybe the worst one would be like hijo de puta. I feel bad when I say I'm like my mom, like, no, don't say that. Right.We're gonna send a clip of that to your mom. Oh, no. She's seen and she's up in heaven.Oh that's right! I'm sorry.She passed way this year. Yeah. Do you want to talk about that for a second. Yeah, we can. Yeah, totally. So my mom, you know, she she's also a big driver in why I do what I do because of her suffering with constipation. And, you know, I truly wish that she would have dealt with her constipation earlier on and had the availability of better doctors to be able to get better because you know what people who have constipation for their lives, especially women and overweight then they tend to be highly likely to get some type of hormonal breast hormonal cancers, right? Like breast cancer, right? You have all this weight, you know, constipation, it just it just it's something that can happen very easily. And, you know, my mother's, you know, was one of my very first cancer patients actually, but fortunately she beat stage four breast cancer. She beat it. At stage 4?She did comp a mix of we were so fortunate we actually like we're very personal close personal friends with the oncologist at our hospital because they've actually kind of given her nothing's really going to happen. But we were able to get her breast removed we were able to like do both chemo and radiation. And then she she, you know, suped it all up with adding and all the natural stuff on the side with naturopathic medicine and she did awesome and she survived 10 years 10 years and then what end up happening was it was a stroke. A hemorrhagic stroke out of the blue. But you know, we got 10 more years, which is amazing. And you know, you know, but if she is still like to this day if she had worked better on, I think being better at her bowels. When you're better with your bowels Your life is simply better. Like it's it's just it's just the way it goes you feel better when you poop better, right? Like there's no...Well I think that if you have a if you go to your website, you've got the 50 shades of poo.I love that. Yes, my fifty shades poo. My nasty little secret.So she's got her 50 shades of poo, which you gotta talk about that that really, when we see how people are digesting a lot of that actually can come down to as a kind of a window into what's happening in your body. And so yeah, yeah. So I'm so sorry that your mom died this year.Thanks Ken. Yeah, you know, it has been definitely a huge journey and a lot of it has brought up a lot of different things because she was truly the biggest believer in me, you know, and so to lose that force behind me, but I haven't lost her and that's the thing truly like she's actually here constantly and like, I feel her presence completely. And so I feel guided by her and, and her passing actually just makes me makes me must have this and help more people more, you know, because my goal is to actually reach a billion people and I will do that this is a must in my life. And and the reason why is because, you know, 20% of our population actually deals with like constipation or some form of digestive, like problems. That's a billion people around the world.Oh, it's huge. It's huge. In in certain countries. It's really interesting because when you look at different countries that have digestive issues, it really is the Western world. And now as other countries become more westernized, they're starting to develop these same things. Latin America. Latin America. I mean, Brazil is one of the largest IBS populations also. US Brazil, and then we have these different countries and so, you know, we've always been taught that 20% of the US population has irritable bowel syndrome. And there's that is my explanation as to why we have this huge increase of autoimmune disease and all these other things.Yeah. And the thing is what's really cool is this. So I found stats on constipation, it's 14% in North America 21% in Latin America countries. 7.8% in Asian countries. So it just goes to show right like, and you know, Latin America, like I could say that being a Latin American is that it is it is definitely getting corrupted with a lot of the North American, like the SAD diet, like the standard American diet is really infiltrating into that.The SAD diet. Stsndard American diet. I have never thought aboutYeah, right. Like, because it's like, I mean, you know, and not all Americans are a SAD die, right? Many of us are like, I feel like I'm an American. Many Americans do live a good healthy lifestyle, right. But there are those people who are eating a lot of packaged, processed, you know, fast food, and that's the majority of their of their diet. And that's the type of diet that will really, you know, like be a detriment to your system. And you know, Latin American countries are taking that all up as well to, you know, and I think just just sometimes too, they do eat a very starchy diet and heavy starches also can be a problem for constipation. So that could be a thing too. But it's it's it's really interesting and this is a must for me now like, really I want to help people because my mom's passing I know I probably would have gotten another 10-15 years had her constipation not be a problem and then her not having cancer and not having those, those struggles to go through in life. How did your sister handle it?My sister, so interesting, you know, she couldn't even watch her pass, which was she ended up coming into the room to watch her pass, but she didn't want to. And I found that very interesting, because, you know, she's a healthcare professional as well too, but she's a dentist, so she doesn't necessarily deal with death and dying. You know, I've seen quite a few patients death, and I've been at their bedside for death and dying with my cancer patients. So I'm more used to it so I could deal with it, but my sister keeps on going. That's what she does. So I'm a little bit of the emotional wreckage you know, that like falls apart and is like, you know, crying for months on end. I actually took a sabbatical from clinical practice for six months, Six months? Yeah, I've never done that before but I just need I needed time. Because that was that was an important it's it's one of the hardest things that you deal with when you lose a parent. Right? Like, like the only other thing that I think could be worse would be to lose a child. You know, cuz you never want your children to leave before you. But losing a parent is detrimental but it has also given me a lot of strength. So I feel very honored to have been on that journey with her.Yeah, I lost my dad when I was 21 before I went into medicine but, but I always find it interesting when medical people have to deal with death or illness. And you know, you just start looking at things a little bit differently,Huge differently. And it's funny, we couldn't do anything for my mother we had no, there was nothing to save her in the stroke being hemorrhagic like is just like she was bleeding like they could have gone and got into her brain but we said you know, what are we doing? Like that's not going to be good quality of life. We don't even know she'd come out and she would be a vegetable. And we figured you know, this is her time. And and when I did see my sister was this is that her and I both tried to become the doctors when our mom got the stroke. Right? And but I, I not so well because I get too emotional. So I'm like, I don't want to treat family like you can't do it was too close to you right? But my sister got into like Dr mode, right? You want to see the scans you want to see this and I'm like thank God at least you can do that and I'll I'll be the emotional support you will be. So we're good team that way. So thank God. That's awesome. Yeah.So getting back to when you finally discovered this castor oil pack. So what did it do for you?Well, immediately I started sleeping better. And immediately I started noticing that my my bowel movements were better, better formed. I'd had them a little bit more frequently or when I did have them I'd actually go more. So I'd have more eliminate all at once. So I was pretty impressed with that and then and then you know of course I was also doing other things I was getting IV therapy. I was I was doing other things on top of that. Because I wanted to get better and I wanted to get back into my life right. I felt like I was having to take a big pause and a break and I wasn't happy with I really wanted to be back in the joy of what I was learning and doing. And so I started, I committed to myself to do these packs every single night because I wanted to feel better and that's what I did and and and I thought I would have to take a lot more but only and I ended up having to take one little semester and I got right back into the groove of things. And honestly, I feel it was the castor oil packs that really did something different for my body. And and what I ended up learning and researching years later was that it it of course it works on the digestive system and on the guts and on inflammation like castor oil is a well known, you know, topical, anti inflammatory, it does all those things. But what it did more than anything was that it changed my stress state. It moved me from being in the stress to sympathetic, you know, hardcore, constantly wired to be stressed out. And it moved me into the paused state which is like the parasympathetic and the relaxed state. And I think that above and beyond everything is what I needed more than anything, and I needed to be able to sleep better so that I could I could heal better at night, right? Because I wasn't healing good at night because I couldn't sleep. Right. I would spend hours just like in my mind.I think that that is it's really interesting. And I want to geek out. About castor oil. I'm not very familiar with it, certainly the topical application of it I did a little bit of reading about it. But what's let's get back to the whole stress aspect. It is so fascinating that I have so many people that will go through a profoundly stressful period, and then develop a significant disease. It's almost like insult to injury. Yeah, I'll have people to go through a bad divorce and then they'll show up with crohn's. They're like what there has to be some sort of correlation, all of this with the cortisol and just these inflammatory markers that are all going up. And then don't even get me started. I think that the three pillars of health are our gut, brain and sleep. Basically, we need to make sure that we decrease the inflammatory process in our brain. We need to protect the gut, and you gotta sleep.See I say eat sleep, poop. But the brain is in there for sure, I think the brain is just an extension of the gut. That's my that's my perception of it. I've got, I've got a talk that I give and quite a bit of data where I can actually show that they have taken. And so a lot of lot of traditional doctors will not discuss leaky gut. And you know, but if you say, Oh, it's intestinal permeability, maybe that'll be a little bit more, but it's really well known and they're documented does some people say there's not science, I've got thousands of articles documenting a lot of this, something really wild. And this is how I end up telling my patients I'm like, Look, they did a study where they took human digestive tissue and they put it with inflammatory markers. And then I checked the permeability of it. And they actually showed the different things like zonulin like leaked through and stuff, and then they had different sizes. So there, that's an in vitro study, then there's not a blood brain barrier, same exact inflammatory markers, and they, they show that the blood brain barrier becomes leaky. So we've got leaky gut, leaky brain, it's all tied together,All tied together. And then so this is a thing to talking about cortisol Is that the research that I've looked at is mainly that my focus has been a lot on the stress component and cortisol and and my research has shown that whenever there's an elevated level of cortisol, your gut is impermeable so it goes completely together is that you know like it's that inflammation back to the chicken and egg we were talking about earlier not the chicken under the bed but the chicken and the egg right the chicken and the egg where it's like it's you got inflammation first and then you get stressor you get stress and then you get inflammation so it that's that that whole that's what's playing out there with that. Alright now let's talk geeking out. You are now going to become a teacher to me.Absolutely! Love it!So castor oil. You on your website you have it is the castor oil pack that you wear. yeahSo just tell just teach me just I don't know shit about castor oil. Well, I'm going to show you how to shit with castor oil. But not early. So we all know like Castor Oil of course you know that's it's it's approved by Health Canada. It's approved by the FDA orally for use to for bowel movements or for constipation right and actually at the turn of the century castor was one of those oils that was you know, everywhere and all the little like apothecary pharmacies, right and they would use it along with like things like Ipecac and those all those old herbs. So castor oils are super cool. castor oil actually is a plant of vegetable vegetable plants, some water in a vegetable plant and this vegetable plant actually what's so cool about it is that the bean will kill you but the oil that is extracted from it will heal you so the bean is actually used in like warfare. It's like a biological weapons that it'll kill you it'll stop your DNA replication and they'll kill you within like six hours if you take enough of a dose.The whole been like if you just eat it.Yeah, yeah, yeah, the bean I mean can kill you. So it's, like so many patients have seen it on like CSI and they're always like, Oh my god, I heard that on CSI about like the castor bean. It's like a biological warfare. It's neat. But the oil when it's extracted and cold pressed doesn't contain the component that kills you which is the ricin component. So yeah.Oh wait. Ricin?Yeah, that's from he castor bean.Yeah so ricin it kills you right? It kills your ear it like block your receptors. Oh! I had no idea.Oh yea it's potent neural toxin. Ricin comes from castor bean?Yeah. Castor bean yeah ricin comes from the castor bean. So so the castor oil though however does not contain that, but how castor oil actually like if you were to take a spoonful of castor oil to actually have a bowel movement. What ends up happening is it's not the people think that it's the ricin that makes you you know have explosive diarrhea. That's not the way it works. Castor oil stimulates nitric oxide production within the gut, nitric oxide production within the gut which nitric oxide of course is healing Of course, you know, that simulates paracel in it's a speak to me about it. About nitrous oxide.Oh, nitric oxide. That's that. So nitric oxide, the reason why I'm super interested into it and we know that that is the molecule that stimulates vascel dilation, which increases blood flow. And so we're real big in nitric oxide because we have been working with some sports medicine people without Antrantil, and I'm here once again, plug Atrantil, sponsor of the show. So what as it turns out the polyphenols in there, they actually have been shown to increase nitric oxide. So for sports recovery. And it decreases reactive nitrogen species reactive oxygen species so so we're so we're super big about nitric oxide.So and this is what one of the actions of castor oil does. And so which is which is amazing. And nitric oxide is also, you know, in other research, they're using it as antimicrobials. So there's some really neat, neat, neat research and they actually use it on catheters and such they'll they'll put nitric oxide on it in order to help reduce infection rates. Yeah, it there's that there's really neat, neat, neat information coming out with nitric oxide Of course, it's a you know, gasotransmitter of the digestive system as well too, but the nitric oxide is one of the mechanisms of action but there's also castor oil also stimulates PGE3 and it's it touches on to the receptors in the gut that create parasol cysts. So that's how it gets yourPGE3 is a smooth muscle receptor.A hundred percent exactly so so it creates a paracelsus and smooth muscle of the body if you take it orally, so in the digestive tract but then also in the uterus so that's why there's a contraindications so don't use castor oil if you're pregnant unless you are inducing a baby and you've been you know your midwife or someone has recommended to do that. Because castor oil will stimulate any sleep muscle in the body to go to the bathroom so uterus is the other smooth muscle of the body. So that's enough action to go to the bathroom. Then castor oil topically has been compared to capsaicin which is like hot red hot chili pepper, and red hot chili peppers are known as a very good anti inflammatory The only problem with it is it makes it red and a bit burning is called a rubefacient effect. It gets it gets really really red into the skin when you put... Rubefacient...Rubefacient yeah, right.That's a big word. I didn't learn that in medical school.No well hey...I love it.These canadian naturopaths are smart!So that reddening is uncomfortable for people right and then of course you know like think about it you get like chili pepper on your fingers or your hands what happens if you get a close your eyes it's like burn, so you don't want that but castor oil has the same effect in terms of like reducing edema, reducing the inflammatory markers and not and and not oh also reducing substance piece so your pain perception is reduced with castor oil topically and it's an amazing oil.So it does this topically but that you had a systemic effect. So how does that happen when you put soemthing on topically?So it has to do with the the triglyceride chains in the oil of castor oil. So castor oil is composed of mai

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EP204: Weekend Wellness - 4 Things Your Supplements Should Never Contain

Play Episode Listen Later Nov 8, 2019 15:39

Timestamps 3:14 Number 1, 5:17 Number 2, 6:34 Number 3, 7:56 Number 4, 9:30 Quick Tips Links/Offers The Danger of Certain Synthetic B Vitamins Titanium Dioxide & Inflammation Research Titanium Dioxide & Nutrient Absorption Carrageenan & Inflammation Stearic Acid & Immune Suppression in Mice Carrageenan & The Immune System Research The Truth About Iron & Oxidative Stress With Morley Robbins Whole Food Vitamin C vs. Ascorbic Acid With Morley Robbins Paleovalley Clean Supplements Grass Fed Organ Complex - nature’s multivitamin made with gently freeze-dried organ meats from 100% grass fed and grass finished beef Essential C Complex - immune-boosting vitamin C from whole organic acerola cherries, amla berries, and camu camu berries Apple Cider Vinegar Complex - fat burner and digestion booster with organic ACV, turmeric, ginger & more Turmeric Complex - inflammation fighter with organic turmeric, ginger, rosemary, coconut oil & more Naturelo Supplements Concentrace Minerals Drops Nordic Naturals Fish Oil Rosita Cod Liver Oil Gaia Herbs Just Thrive Probiotics Atrantil *For the sake of transparency, this link is an affiliate link which means I receive a percentage of your purchase. If you’re uncomfortable with this in any way, please just google “Atrantil” and order directly from their website. But if you’d like to support me and the free content I create, it would be greatly appreciated. :) 10% off COUPON CODE for this episode is "ww10" Connect with me on Facebook Connect with Paleovalley on Facebook Connect with Paleovalley on IG

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Jeremy Kinder, CBDTakeout, Curated & Trusted CBD

Play Episode Listen Later Nov 7, 2019 73:08

Welcome to the new location of the gut check project. I'm your host, Eric Rieger along with your other host, Dr. Kenneth Brown. How you doing Ken what's going on?So well, we've moved from the Spoony studio and we are attempting our first own podcast over here at the new studio at the KBMD Health studio. We are and guesswhat, you know we are still on the Spoony network, but I can't express how nice it is for you to now have a studio that's closer to the clinic. It's closer to where we do the procedures. It's the same distance for me no matter what.And most importantly, it's closer for our guests like Jeremy who just flew in from Austin. All the way from Austin because we got so much closer. Yeah, thank you guys. Much closer. Awesome. So our firstguest here in the new studio is going to be Jeremy Kinder here with CBD Takeout and I'm going to let Jeremy kind of take it away a little bit about what is special about CBD Takeout here in just a moment. Dr. Brown real quick, do we have any catch up items that we needed to do to kind of put in front of Jeremy to see if he wants to weigh in on anything?Well, we got like several visual on so first of all, we want to hear the story about how you and Jeremy met Sure. We want to talk about how much synergy there is. Whenever you start meeting people and you start connecting with people. We came back from the baby bath water event and just met incredible people. We had Tim powers over here who we're going to have back on because we actually had the equipment. We were unpacking the equipment when our first real guest showed up and he was kind of helping us just show how to...like we were like wiring this stuff together. Check thisout. Before Tim came over here, he was over at a hotel and then put his iPhone down to simply turn around and pay a guy at the bar. No, no, no, he was going to turn around and refill his ice tea. Oh fill his iced tea.Like five feet away at like a Homewood suites are just like some. Yeah, you know, like normal family.A little hotel. Did somebody grab his phone? Withinlike three seconds, three seconds took off. So he was in town. And so me my wife, my daughter, my son was out of town, me, my wife and my daughter, we're going to take him out to dinner. And I pick him up. And this is what we have to do is figure out so now we're, I'm learning how to move the camera. So now we're back on me. Yeah, nice. Sweet. So we're working on that. And I picked him up in like a boss. I mean, like a boss. He was like, Hey, man, what's up? I'm like, why did I have to face you know Facebook you? Yeah, funny thing and he stops in the car, funny thing my phone just got stolen I'm like when? He's like, I don't know eight minutes ago. I'm like, you are a boss. I stopped the car. I'm like do we go to BestBuy? Do we get you a flip phone? What do we do here? This is crazy. So was he calling youfrom like an iPador something? He sent me and I'm not a Facebooker and so he sent me a message said hey, phones, phones not working. It was cool about it phones not working. message me through this and I'll I'll do it through my iPad. When I picked him up, I mean, he was just like, I would have been curled up in a corner, crying, whatever. And he's like, yeah, let's just go to dinner. It's all good.Let's go get a drink.Let's just I mean, he was just cool and super, super neat about it. And then that evolved into a realization for himself and go ahead and expand on that. The coolest thing was is he found how addicted he was to his smartphone.Yeah, he said he began to sleep better, he communicated better with people that are in front of him. His anxiety level, he said, the first day was palpable, where he didn't feel captivated by the phone constantly vibrating for something for him new to look at.So, man, I don't know how much y'all want me to talk because I bet I'm a talker I'll throw in stuff on everything. But my wife and I have been talking about how do we decouple from our devices and I've tried everything if you're getting a second device or getting an Apple Watch and you know, all kinds of different stuff and honestly, the thing that that's helping me the most is just discipline you know, but I'm not going to you know get on my device and it's freaking hard I mean it's really like a you know like a drug fix of it My mind is telling me Hey, I need to check my phone go through the cycle of okay check Instagram, check the email check, you know. And then 15 minutes later I've been on my phone the whole time and I I literally don't need to be on there. But that's probably about a year ago we started talking about how how we can improve our lives and have better sleep quality and a lot of that stuff and decoupling from electronics was a big part of thatI don't remember was that Aaron File at baby bathwater who made the statement that there's a boxthere's a box..No it was Jack Olocka. Oh Jack Olocka. So it was Jack Olocka . So Jack Olocka...I'm a little bit echoed here. Is that you know what, whatever we're just we're just gonna run the first one is studio thinking first one new studio figured out. So Jack Olocka . So Jack, so this group that we're with is like, it's like, you know, like when you like meet a bunch of people and you just go oh my gosh, I'm I'm like around a bunch of like minded people yeah well Jack Olocka is a PhD in psychedelics, all his research has been in this and like not like, Oh, I'm really good at psychedelics like he actually has a doctorate on the neuro plasticity and what happens I mean, just brilliant guy. And he gave a little speech there's this thing called a Baby Einstein, we're just going let it echo doesn't matter now. Where the Baby Einstein where everybody kind of gives either an ask or a give. And you know, his give was there's something called a kitchen safe. And what you do is you put your phone in the safe in the kitchen. Yeah. And when you set the timer, you nothing can get that phone out until the timer stops. Like there's like like even if somebody breaks it, it's just pretty much like yeah, you better have a landline going Yeah, yes. You know. And so unless you have dynamite and a crowbar and the reason is is because people are so addicted to their phones and we know that the blue light affects sleep. If you look at the how important sleep is and how affected it is just getting in just shutting your phone off and not looking at it is probably the most important thing that you can do.Yeah, yeah. My problem though, is you know, I come from the technology world and my house is wired like I have sono speakers everywhere and I have lights that are on smart plugs and all that stuff. And I did all this before I knew the the harmful effects of emf and so now I kinda thinking. So if I put my phone in a safe like I can't turn my lights on or I can't listen to music. Or turn the air conditioner down. I'm hosed. Just honey. I can't flush the toilet. Right. My phone's in the safe.Yeah, yeah. So you know we're talking about how to it maybe shut all that down and all that butyeah. That's funny. So let's talk a little bit about CBD take out that's why you You came up here today we're going to explore opportunities that are synergistic between the two of us. I was going to kick it off by saying one of the things that allowed you and I to get on this wavelength to start talking. So I went down to Austin to join a friend of mine. Marie and I are really good friends with the Leath's. Rennon Leath is basically the founder of a podcast called Lazy Sundayz Lazy Sunday, Lazy Sundayz and that's with a Z. So lazy Sunday's podcast. It's really kind of cool. It's four people who got together and have anxiety issues. So they forced themselves to start a podcast to confront their anxiety and now they just recorded their 50th Show and The 51st comes out this weekend. Yeah, so They wanted me to come down and help him see it. They held it at the Tequila 512 headquarters. Thanks to Scott Willis. Oh, can you do me a small favorover there and hold up that bottle. oh yeah that's the old vintage bottle. this is so now I'm going to change the camera here so this is the vintage bottle. This is the original bottle of tequila 512 that when a they were in a tasting contest according to your buddy there that he said that they call this a shit-tastic label. They did. Shit-tastic.Once they replaced it with the new and they said yeah old label kind of cool pretty shit-tastic . Yeah,the tequilas phenomenal . The label is bad. So can you guys hear that?Yeah.I don't know. Maybe it? Is it? Is it too loud on me? It's been first podcast.It might just be the headphones popping?I don't know. It's probably something that we did with the microphone.Ron. So run. Shout out to Ron and Paul, everybody else that helps us out with this that they're going to be dying laughs I'm going to try and puttogether Episode 21 good content from Jeremy bad audio from me.So, anyway, we go down to do the podcast we did it at Tequila 512 casita there in Austin and man great turnout. Yeah, they had what...60 people? I was running down to the liquor store trying to buy more liquor. Yeah, everybody was having a great time. Theymaxed out the what 512 made available to them. Yeah. And then we had to shut the party down at nine. That was the rules of that particular neighborhood. So, great podcast, great turnout. And then Jeremy, I'd heard Jeremy's ads on the podcast previously, I've listened to my friends podcast before and I was really intrigued because your first and second interview specifically talked about what y'all do at CBD takeout is essentially you're going to find CBD on CBD takeouts website. It's been vetted. You've made certain that the certificates of authenticity are real, and that the measurements of everything that's in there, it's real CBD per the label that's given to you now. It was at baby bathwater that we learned that just on the retail side 26 to 28 offerings of CBD to 1 are fraudulent for every good one was 26 to 28, which are not so thankfully for someone like Jeremy and CBD take out. This is a bastion of where you know, everything that you're going to find on there is vetted. And I think that hopefully over time, you'll find the KBMD will be a part of their repertoire.I think that would be awesome. And so I mean, Jeremy just get everybody up to speed you come from a long lineage of CBD growers. You're the seventh generation of a hemp grower you have extensive experience with CBD, your great great great great grandfather was the first original CBD producer. And now you decided to go digital but am I a little off on that?No that's spot on? I guess you read my bio. Yeah, like that couldn't be further from the truth.No. So my, my career's been is in technology, so I've worked for a lot of software companies and sold, you know, really high end platforms to major corporations and may have had a great time doing it, But I wanted to do I wanted to do something different that I was passionate about. And so at the same time that I was building technology companies and doing all that I just have always had a passion for health and fitness. And I think that that goes back to being a collegiate collegiate athlete. So I was a cheerleader at the University of Kentucky. Oh, yeah. went there on a full ride. That's fantastic. died doing that. Yeah. My wife's also a cheerleader. She was a cheerleader at the University of Texas. So, you know, we grew up as gymnast and so athleticism is in my background. But then about, I don't know, age 21-22 I started and that's really kind of when things peaked I started having gut issues. And back then I didn't mean that was, what 25 years ago, something like that i there wasn't research that was readily available, you couldn't go to the, to the grocery store and find gluten free products, none of that it was really really difficult. You know, I went to doctors and had lots of blood work done and they always came back with your you're healthy, you know, but I didn't feel something just didn't feel right. And so that kind of started me off on this whole exploration of, of diet and trying to find balance in my body. And you know, I've been tweaking that for 25 years and that that's what really led us to starting CBD takeout and and getting into this industry.Were you ever normal or more did you actually feel that there was an event that took place that changed everything?Yeah. So when I said that, you know, around 21 22 is kind of when all of that peaked when I started peeling that onion and going back, so I had spinal meningitis when I was six months old. So massive amounts of antibiotics, you know, had IV's in my head, all that good stuff. And, you know, at that point, nobody really knew about balancing flora, and that, that antibiotics could basically just kill all the good bacteria in your gut. And so I think from, you know, six months old that I was at a disadvantage. And then by the time maybe 15 or so, you know, just like, you know, normal teenager started having acne, and I got on tetracycline, so I took an antibiotic every single day for, you know, maybe two years. And I remember around that 15-16 I remember my body changing not in the teenage way. Just I remember Remember things with, you know, with going to the bathroom and stuff like that, that there were changes, but I didn't know. I didn't know why. So I started having a lot of athlete's foot and a lot of rashes and stuff like that. But so it was there an event? Yeah, I think there was probably a lot of events along the way that then you couple that with a college life style of shoot we were we were sponsored by Papa John's, at the University of Kentucky. I mean, we could call up and get a large pepperoni pie for like four bucks. We were We were rocking that every other day.I have this image of Jeremy and his buddy catching that one cheerleader that they throw up in the air and she keeps getting heavier as the season goes on. It's like yeah, we gotta find a new sponsor.Yeah, yeah. What thank God we had ephedrine back then.That's great. So Jeremy, when when you realize that there was an opportunity there to basically take...Well, no, actually you went to this where you are starting to realize some changes. So what progressed? And how did it take to take you to where you are now?So back that up to the question? So how did my dietary issues affect? So yeah, I think that that that just spawned a passion within me and starting to research that there were ways to put my body in a position that it could heal itself versus looking to a quick fix of let me take a pill let me you know, kind of that that approach tothis was during college when you were starting to think about this, or when did you start to do this? Yeah, yeah, that's, that's about right. It's really interesting, because everybody that we've met, that we've met in this field, when they start doing that they really get drawn to medicine. Yeah, and you didn't. Well, I, I mean, career wise.Oh, gotcha. Yeah. So I think What I really contemplated back then getting into more of dietetics and and going about it from the diet route, but man I am not a scientist by nature I think and and even at that stage that the issues that I was having, that you have concentration issues so, so to follow a, you know, a profession and medicine, It just wasn't in the cards for me So, and plus I like to talk so it kind of led me into more of the sales avenue of business.You know, Eric puts people to sleep for a living and he talks the whole time so you can still do medicine. yeah, you can do it, but they don't ever respond to anything I say. So yeah, pretty much.Yeah. He has full on conversations with all my patients and they wake up happy like subconsciously they love communicating with Eric.Yeah, it's always a good dream. Yeah.So obviously then you still pursued, your career, you said that you got into software sales correct? And but you didn't lose the passion for trying to find something that was going to allow you to heal. And I like that you say it that way, find something to heal and not a quick fix. Oftentimes the companies that cater to the medicine world now, it's pharmaceutical, and it's always a quick fix. It's a patch. You know, I didn't know that growing up. I always felt like well, you may be dependent upon medicine that's just the answer. And what I've learned is that's oftentimes absolutely incorrect. You can learn to heal from the inside and get so much better. So what turned you to that for your own personal health?So the point around pharmaceutical companies and that methodology if you look at foundationally how how they are built, they're not financially, they're not, they're not compensated to heal you, to fix you, they are compensated to get you on a regimen, that you come back and be a repeat customer. If anybody knows about publicly traded companies, the the end goal is to increase the stock price. So pharmaceutical companies, they they don't have and this isn't a political statement, this isn't a perspective of whether they're bad or good. It's simply foundationally they have to satisfy that stock price and if they get people off of their drugs, then that stock price does not go up, it goes down, right? So, from from that perspective, they they are not going to be in the business of healing people.clear my throat there. It's alright. Sofrom the perspective of,of healing yourself, I come from the perspective that of that we're creative beings and then We, God created us in a way that we should function properly. But what stands between us and that is desires. So does the food tastes this way? Do you want? Are you chasing the way that that tastes? Or do you not want to exercise because you're too tired? So there's the I think that there are things that stand between us living an optimal life, that it comes down to choice. So I begin to peel that onion for myself in my own life of what was standing between me and optimal health. And over time, you know, I have experimented with different supplementation or different diets and so on and so forth.So that my perspective. I want to expand a little bit about what you just said, because that's never really been addressed before, which is that our health is related to our desires. Now we know that fast food industry we know that processed food industry, they hire, I have patients who are chemical engineers, their sole job, and they've told me this is to figure out how to make the food more palatable, more satiable, more like everything about it that you want more. How do you put a coating on a freedom? So it goes down easier. Yeah. So we have the pharmaceutical industry over here trying to combat high cholesterol, obesity, coronary vascular disease. We've got the food industry over here trying to figure out how to how do I get you to eat more Doritos? How do I get you to eat more Fritos? And I love how you said that because what you basically said is something I've never thought about. We battle our desires, but our desires are influenced by both the media scientist there's some really smart people trying to get us to take certain things.Certainlylet's go back to the beginning of this conversation was about technology. So I was in the technology business, and the exact same thing that you're talking about of how they create foods so that they're more palatable, they look better, whatever they do the same thing with, with technology. So your, your phone is created in a way that they call it gamification. How, how do they attract you? And it's really like a drug, how did they attract you in a way to keep you using the device? And once again, I'm not saying something bad about the company companies are here to be to be profitable and build a company. It's up to us to choose if if we're going to engage that or not. So it goes back to your desire. Are you do you have fomo right? So do you have to look at your device and start figuring out what am I missing? What am I missing? And I need information or you know what be at peace that you're world and things going on in your life is what's important to you versus everything else.We're getting super deep, real quick, but I asked just another No, no, I love it. But I want to ask a couple quick things because Eric and I talked about our family and our kids all the time. You have kids, family, wife married Tell me about that real quick. I've been married for 17 years.Two kids, 14 and 8. Two girls. They're fantastic. Beautiful.Yeah. So the reason I bring this up is because a lot of times since I've had kids, so I have a 14 year old a 12 year old about ready to be 15 and 13. Eric has his sons. And when we sit there and you live your life, when you start thinking how do I want my kids to live? It really changes your perspective. For sure You suddenly just go Oh, no, I want and the fomo thing like you don't realize that you're on your phone, but when you see your kids on the phone, you go Wait a minute, and they look at you and go, but you're on yours. That that puts you in check. I mean, Eric and I talked about this all the time.Yeah, it's difficult. I remember the when Ken and I actually just started working together. Whenever my oldest got a an iPod, they would communicate with other iPods. And I remember saying, Man, this is kind of weird. I don't know if I like it or not, but he does every now and then need a ride because he's going to soccer and basketball back then. And it helps. Maybe it was the lure that conveniently lure at that moment sank its little teeth in and then about three years later, he's got a phone and then suddenly we're like, well, that's certainly certainly is convenient in the younger we didn't have to wait till he was the same age. He actually got one about nine months later and honestly, looking back at it, I wish we had just never jumped off of that cliff. I do think that we both Marie I both have looked back and tried to carve out the time that we just absolutely don't have a phone at dinner when we're having family conversations etc. But the thing that stinks, is it when it's on you and you're not planning the formal talk with with whomever you whomever you're talking with even if it's your family sometimes you like oh yeah, yeah, two seconds let me finish real quick. That never existed growing up and in all I feel is more fatigue at the end of the day just because of that.It's kind of weird. So wesomebody shared with me this YouTube video that you should probably share with your daughters. It is a Harvard psychologist which is talking about the affects and I've shared it with Eric before but it's essentially thatthethe fact that we have these desires and things when we get a like or and I say we because we're all human or get a like when we get a share when we get whatever it releases dopamine. Yeah. And dopamine makes you feel good for a quick second.They knew that when they created it. Isn't that nuts? For sure that's nuts! It's the gamification.See that molecule right there? That's dopamine, advancement of dopamine because we sit there and look at this, and I just think, wow, I want to actually...when we talk about it, we don't want. We don't want dopamine pleasure, you want happiness, Serotonin is the happiness molecule. And when you release dopamine, you actually reduce your happiness molecule, which is serotonin. So everything that is done, and unfortunately stopped, sorry. Everything that is done is to get people to do more of it. We're talking about tequila companies we're talking about. And the beauty is this is a great segway for us to talk about this, that this isn't a discussion of desires or everything. It's a discussion of how do we start healing? Yeah, well, one way to start healing is is that because of all this crap that's going on, we as a society, have an Endocannabinoid deficiency. And I think that's kind of what you were gonna get at that you were you went from the space of digital to realizing I need to start helping people.Yeah. Well, I got to this place in my life whereI had enough money to where I could just say, you know what, I'm not going to do this anymore. And I mean, we could go down that route of, should I have done that in the beginning anyway, I don't know. But I decided I'm going to apply everything that I've know that I've learned to this point, and apply it to something that I'm passionate about and giving back to people. So all of this research that I've done, and you talk about not going down the route of, of medicine. I did it in my own way. Right. It was, it was experimental. And, and so I gained a lot of knowledge along the way of what worked for me and I wanted to I wanted to give back so we took that that knowledge especially in the technology space and applied it to I mean if you go to our site it's I'm going to brag a little bit our site is is fantastic. We've got a....what's the URL real quickCbdtakeout.com so we've got a bot on there that readily answers questions now it's about to get an upgrade so he's not perfect right now but we're we're growing and we're we're making updates to the system but technologically we're we're, we're spot on. So we wanted to build a fantastic site that was really easy to use. And then we saw an issue in the market with this flood of CBD products that were unregulated and because I have toyed with supplementation for so long, I there's so...You can say so much and it's hard to weed through all of that junk and so we wanted to help people by vetting those products and having a marketplace of fantastic products in one place that like you talked about that have the the lab tests and every product has the lab tests that you can pull up and see on our site.That's awesome. I think it's I love it when people have a success in one industry and then want to give back. That's essentially what you're saying.Well, I wanted to do that all along, but it...No we don't want to tell our audience that I made you take off all your gold chains and your watches and what you've got like for Lambos out front right? Right. Not that well. I can just pay my bills. Let's say it that way. But it is it's just fascinated because you come from a background of health and there's no doubt about it, dude. I mean, Kentucky cheerleading. I have had friends that have been cheerleaders and they're like the most. I mean, they're like now CrossFit beasts that I work out with. I'm just like, holy cow. Yeah, these guys like that is hardcore. Yeah, Kentucky cheerleaders a dynasty. I think they're on their 23rd national title, I lose count. But my my teammates still a coach their Jamal Thompson. And they are, they are beasts. They're fantastic.It's so I mean, essentially you're a an elite athlete, gets sick, tries to discover his route develops a successful business. And then wants to give back and you're giving back by CBD takeout by trying to make sure that people have access to proper material, proper products, proper supplements. I think that's fantastic.Yeah, I think the other thing to say there is, we were dedicated to the process. You know, when there's a product that everyone wants and needs, it's very easy to get on the latest gimmick and we refused to do that. We We're taking our time to vet these products to vet these companies and, and really vet the trends. And that's that's not easy to do that takes a lot of time to figure out what is right for for people and what products are right for people. So that's important to us.I was just looking at something because I don't hardly ever get to correct anybody but I want to have some fun since you went to Kentucky. Kentucky did win a ton of national championships in a row. And they finally were unseated by the Texas Tech Red Raiders this last year. I just had to throw that out there. So welcome to the show.WhichI love the I rarely get to correct anybody just asked Marie. Yeah, I'm going to use this opportunity even though we're on our first podcast and I'm going to insult our first guest, but I never get to do it. I never getto do it and do it becauseHave you seen Scott yet?Since we were... Oh no I haven't. Okay well the nevermind. I'm holding that okay. Yeah okay. But back to Texas Tech now look them up and see how many they have won. I think it's one.You're right. We just did it we just did it so you can come on the show.In fact, you know, they are always...I work for the organization that you know for that competition. Varsity spirit worked for them for a long time. They want someone else to win because nobody wants to go compete because like well, Kentucky's already won and the competition hasn't started yet. So there are they're actively hoping that someone comes and beats the team.I went I went to the football game this last weekend because gage went out to go visit Tech's campus and when we were there, they talked about how there was finally a school to unseat Kentucky. Yeah, I'll still give mad props. I mean, that's, that's a huge thing. I mean, so it's basketball and cheerleading. Everybody knows that about Kentucky. It's becausethe university really supports the program. If you go to other universities, they just don't support the program and I understand cheerleading is a huge liability and it doesn't make any money. Kentucky just really appreciates. I mean that there's there's been a guy there. T. Lynn Williamson he is the university attorney. And he started the cheerleading team at the University of Kentucky. Dedicated.How dedicated Kentucky is to finding talent, too. He doesn't come from Kentucky. He's originally from Denver city, Texas. Yeah. Yeah. I'm from Texas.Yeah. How'd you end up going to Kentucky? Doing cheerleading? Yeah, yeah.So I went to a junior college first. And I got recruited. So the junior college I went to was really good at cheerleading as well. And you come from a background of gymnastics is that correct? yes. Yep. Man that's impressive.Well, now I'm just old and...You're not that old.So one of the things I want to ask you did you have to quit gymnastics after you grew the mustache because the aerodynamics threw you off, or is that something that you can still do gymnastics with? Actually when you twist it makes this cool whisp.you spin faster.So one of the secrets if you guys are not out there the reason why Kentucky wins and gymnastics every year is that all the men have to have mustaches because it actually it actually augments the twists and turns. Yeah, yeah, that is awesome. So you have this really kind of cool background and then you do CBD Takeout and you're doing it for one reason. It's one reason is to source proper supplements. Is it only CBD or do you guys have other supplements or what are you doing? So it's all CBD in different shapes and forms, right? We've got salve, we've got capsules, we've got tinctures, we've got massage oils, there's quite a few different we stay away from the gimmicks like CBD candles, CBD toilet paper, that kind of stuff. We don't carry that. We want good value for our customers, you know, if you if you can't absorb it into your system, and there's really no value to it, we don't carry it. But, you know, honestly, I've built a business for scale to be able to help as many people as we can to reach as many people as we can. So in terms of direction of will we can carry other products, I'm open to that. Does it help people? Does it increase the benefit of CBD? If there's a product out there, maybe cue Atrantil. That that works together that has a harmonizing effect, we would consider that.When he and his wife went home, he let me know that she'd already picked up Atrantil from people's pharmacy. Oh, that's awesome.Yeah. Well, what I love about this is that you're not doing the death by 1000 cuts. You're staying true to one thing. We're going to do one thing. We're going to build a really good website first. Yep. We're going to make sure that the thing that I'm good at which is digital, we're going to do it well. And then we're going to offer this. Now you have a calling to this, why do you think it's going to make a difference?I think in that goes back to you talking about building it in a way that we can execute properly. I, I'm convinced that and I mean there's science behind this, you can talk about this that our bodies need cannabis. And and so I, I think that there's some interesting reasons why people have been have been kept from cannabis for so long. And I'm frankly I'm just excited to be a part of call it a revolution Call it whatever. I think the impact that cannabis can have on people lives because you can remove so many pharmaceuticals, you can aid with cannabis. And then that puts you on a road. I don't think cannabis is the end all. I think that it can still be a crutch depending on how you use it. I think it is. It has the potential to put people on the road to healing. So I think it's very powerful. I think that there is a fantastic opportunity. If we can wade through all of the noise and trust me people there is a lot of noise in the business right now. The the people that I talked to day in and day out. There's some great people that are getting into the cannabis business, but there's a lot of people that honestly it's the the old culture of just drug dealers that have moved one step over to legitimising and they still have the same principles and so we're really committed to the culture of cannabis and representing it in in a proper way and we could spend probably an hour talking about what I think the the proper way to do that but... Let me just clarify really quick for the listeners here so cannabis what you're talking about right now on your website is purely CBD correc?t Correct. Yes and we split that up. We have some that are guaranteed THC free we've got a filter on that. If you need something that is guaranteed THC free you can find it easily. But everything is hemp derived so it's all . 3% or less so all federally legal.And it's so frustrating because when we get into this we understand that the confusion about it. Cannabis where you're knowledgeable about it because we know that comes from the same genus species of the plant, but everybody hears cannabis and they have a connotation of it.Yeah but in and that's the that's the thing that I'm talking about changing because I believe in the power of THC as well in proper dosing. But here's the thing is we don't even in legal states, the the science has not come along enough for people to get accurate. dosing, time and time again, it's still trial and error. And so while you can't overdose from THC, you know, from a medicinal standpoint where you know, you can't kill yourself, but it can cause psychological issues if you consume too much THC. So that's the culture that I'm talking about where THC has this, this negative connotation because it's been attached to this attitude of rebellion. How high can I get, can I get the strongest THC product available, and I just think that's wrong. And because it's been represented that way, then we don't get the the truly beneficial aspects of THC and and so many people have dismissed it, but then they'll go get, you know, an anti anxiety drug that causes 15 other issues. So how do we move back to this culture of, you know, business people should be able to consume small amounts of THC that are blended with other cannabinoids. So if it's just THC, that's where that's where you have issues with. I'm super paranoid and I'm freaked out. If you were to consume a nice dose of CBD in conjunction with that, it balances it out real nicely. So I just think that the industry is in the elementary stages right now and I'm talking to all of the the entire cannabis industry. I think it's in the elementary stages. And we're excited to be a part of that.You know, we if anybody's interested in getting a little bit more into this Chris Cresser just had a little client in both friends of ours just had a little client who is CEO of oh hi energetics on his show. And Will went into deep detail about the history of hemp, CBD, marijuana, Cannabis, whatever. And it's been ingrained in our culture for so many years, our genetics actually eat a certain amount of it. And one of the things that's really fascinating to me is that we used to feed our livestock, hemp. And when they would eat that, like a chicken would have an anecdote of 250 milligrams of CBDA in it and then our bodies would convert it. That would be the acidic version of it to get all sciency and stuff. But basically, we were getting CBD in our diet until the US government decided to say. Okay, now wait, this is an illegal product, we're going to ban it and then the farm bill came around just recently in the last five years and started changing things and now it's become more available, but I think you're exactly right. I think that the black and white notion of I'm going to get high or I'm not going to get high I'm going to do this and that am I doing something? No I was testing mine. But we're...Eric you could probably attest to this remember that the Joe Rogan does a whole set about how people have done that they get the little gummy. Eric and I, Eric and I are huge comedy fans. Yeah, yeah, like like he actually takes his sons to comedy shows when they buy and don't like to see what you see. Who the guys you've seeing live?In the last year we've seen Bill Burr, Tom Segura, Marie went with us on that and we also saw Hannibal Burris. Yeah. I mean it's it's a pretty rich and actually gauge for his birthday last week he and his friends went to go see Eric Andre that's off the chain. Wild stuff right there.Yeah, Who was the comedian at baby bathwater that just wrecked it.Oh, goodness. What is her name? She killed it. She's a total amateur and just gets up there and just starts. She was inShe was in between bands on the top of a mountain and when I mean she nailed it. It was like, you gotta have your own Netflix special nailed, really. And she just sat there with her iPhone. She's like, I just don't talk about this and just killed. Love it. I respect comedy at that level, just having the balls to get up there and just do it is nuts. No kidding. So anyways, I'm digressing, but basically Joe Rogan does a whole set about how the guy gives him a gummy and he goes, just eat the arm. He'slike the arm? What kind of shit are we making these days? They just are gummy bears.They just they are. I can't tell you how many times I hear that story of people. They're like, oh, I'm going on vacation. My wife and I are going on vacation to Colorado. And we're going to eat some gummies so they eat gummies and they're like, man, I got so high. I was freaked out and like what I mean, that's what I'm talking about. You don't have access to how do you dose properly and edibles are especially bad because you're going through your digestive system and how much did you eat before that? How hydrated you are? So you know the insulin uptake yet all of that... Jeremy, have you ever tried alcohol? Drink this bottle.Right? Right just chug it. Yeah.yeah. Can you guys hear me crackling? Yeah, I don't know. What's up with that?Yeah, I think so. You know what I'm gonna go take a little pee break real quick. Okay, figure we forgot the crackling you guys keep talking and you're on camera right now. All right. Okay so what we'll do is we'll hit here real quick about whenever someone does visit CBD takeout something that's interesting to me. We get feedback a lot about people that take CBD currently and order it from KBMD health. Most of our feedback though, is directed towards people who come to see Ken for gut issues in particular, IBD such as Crohn's, ulcerative colitis, advancing proctitus, even to a lesser extent, a lot of folks who have found issues with celiac disease, but that began to open up a completely different arm of people who have systemic autoimmune disease. So a lot of IBD's are viewed as are viewed as an autoimmune disease in and of themselves, but so is psoriatic arthritis or all the way up to Alzheimer's. Where do you get a lot of your reviews from? Because the thing I really love about your right, your website's great, and I've seen it before, but as I'm watching it scroll now. You get so many athletes on here. Yeah. And Brandon, the host of lazy Sunday'z podcast, has his own CrossFit gym. So the synergy there and your application obviously the way that you're marketing to these folks, where do you get mostl of your reviews and do you see them kind of branch out a little bit?Yeah. So one of the things that we looked at when we we developed a site was what are the the markets that we want to to support and athletes is definitely one of those you can see that pretty quickly when you go to the site. And the reason that we wanted to focus on athletes is because the CBD's ability to help with recovery is is really, really great. So and what I mean by that is I don't think it's any secret that CBD helps with sleep, sleep quality. So if you can improve your your sleep quality, then your body is going to recover better and more quickly and for athletes that that's key, especially within the CrossFit, CrossFit world. It's how much how much output can you get out of your body, and so recovery is the biggest is a big deal there. And then the other thing is, you've got receptors in your skin, Endocannabinoid receptors and so you can use topicals to reduce soreness. So athletes use our products very consistently. So obviously a group that we we wanted to service. Another group is the aging community that does have issues with specifically arthritis, because, like you mentioned, Eric arthritis is a symptom of, of inflammation. And so CBD has shown that it has the ability to lower inflammation. And so we get a lot of feedback from that group. I think also that group is, I don't know, I feel like they are more open to providing us feedback. We get more more feedback from that age group than we do from our athletes. Athletes are always talking about it when we see them, but that aging community man they give us a lot of reviews and feedback, a lot of emails and we hear fantastic stories, you know, you want to talk about reaping the benefits of creating a company. We talked about this quite a bit of, you know, customer saying, I haven't been able to walk in, you know, six months because of my arthritis. And now I it's changed. This was a word that was used, it changed my countenance I had to go look it up. But it really is helping with that arthritic community. In fact, we've written a couple of blogs on on how it helps with arthritis.Wasn't Chad Hudson, his father, one of those that..He was, yeah, he got off of opioids. I mean that that stuff blows me away when we look at the opioid crisis that that we're having in the United States. If if we are directly directly related to helping people get off of opioids, man, I'll keep doing this forever.That's that's, that's no joke. So Ken, just while you stepped out. I was talking about how we get feedback through KBMD mostly it originates around gut health gut issues, gut inflammation about what we've started to basically branch out and get reviews from people going, I have autoimmune disease, etc, etc. But essentially, like Jeremy just outlined, it all is based around inflammation. So according to their website, if you look at everything and it's it's based around athletes and recovery is where they started getting their reviews, but now, just like what we experienced the KBMD health, you're starting to get reviews from all different facets and it's the geriatric community is pretty impressed I think with their, their access now to CBD. And it's unfortunate that it took until their golden years to start finding something that is going to work for them.There's a couple of, if I can, a couple of other areas unless you're going to if you're going to change the topic. We gotta goat in here. We've got a goat. Goodness gracious.So a couple of other areas that we are focused on on the site. One is, is pets because they also have an endocannabinoid system. And, you know, we hear dogs freaking out on the 4th of July.I'm sorry, I was trying to time that to open for you. I was going to have a bark and I tried to download an animal sound and it became a goat. So but one of the things that people don't realize is that goats take CBD too. Yes, if you have goats. Let's make sure that...We have a goat section...look for the goat tab.So one of the things so I I've actually talked to a lot of high goat athletes that have been going to your site CBD takeout Yeah, yeah. These are elite goat athletes. These are goat jumpers goat runners, and they love it.Yeah, yeah. We're thinking about rebranding it to just be I mean the feedback we get from the goat community.Of the animal species they're some of the best credits in there. Yeah. And they can they can actually afford high level CBD.You'll find that selection in your takeout C Billy DeeI was trying to think of something, something snappy, but that was good.I'm really good. I'm really good at URLs, man. Yeah.So yeah, so um, unfortunately, I have to, you know, one of the one of the addictions that Eric does have is that he buys basically he owns every domain name.He spends hours on Godaddy.I got an ideaAll of a sudden you'll be like oh, that'll be funny to have like goat CBD athletes but somebody bought that?I have JeremyKinder.com if you want it?Yeah.Just kidding.20 grand.I'm sorry. No, I mean, the same endocannabinoid system so it it helps with anxiety and you know, dogs freaking out on the Fourth of July and if they have arthritis, I mean it's really beneficial. So we've got dog treats and tinctures and all that stuff for cats and dogs and animals.So let's just really quick because when we talked on the phone, we were talking more like my whole role is science. So not to sit there and a joke about goats and goat athletes and all sort of stuff but let's be honest about something. We we have a system called the endocannabinoid system, just as important as the cardiovascular system, neurologic system or gastro intestinal system, which I'm a specialist in. Eventually we're going to have doctors labeled as Endocannabinologist. Yeah. It's that important that it will be incorporated into med school, we will have specialists. And what we're going to need is people like you that are sorting through people that are just trying to make a buck, and you're able to put stuff up there that can actually help some people. So much like I like a website called examine.com. Where they vet products, you're doing the exact same thing for the CBD industry. And I commend you on that. And I want to thank you for coming out of your other other profession and being able to put your digital expertise into something to help people.Yeah, it appreciate it. You're right. We talked about the mess. I mean, what do you say 22 out of 24 products I don't know.Actually what they said was 26 to 28 to one yeah, is a fraudulent product.I don't know if you guys listen to the FDA hearing on CBD, but one of the things that kept coming up over and over and over maybe the most consistent thing was, how many fraudulent products there are out there. And it's it's bad. And I think, I mean, that's where the benefit of having the FDA regulate. You know, what can be said and what can't you know, from a marketing perspective is important because you've got people that just want to make a quick buck and they look for situations like this on a early to market, non regulated product that actually works. It is a quick buck type business person's dream. But you got to balance that with how do we vet all these products out and vet these companies. And that's what we we partner with those companies that we feel like are going to be there for the long term. And, and those are the products that we have.What I feel I like the most though about CBD takeout and this approach is that oftentimes with something like the FDA, you're right, they may try to put in some tools or mechanisms to prevent something from happening. But what ends up happening oftentimes is they block access to legitimacy. Yeah. So really, what Jeremy and his company are doing, I think, is from the inside, you're basically beating them to the punch saying no no no we've got a mechanism here. We can filter out the bad, we want to bring you the good so having a resource like that to turn to say, if I shop here this is where I'm going to find the high quality product it's no different than going to a natural grocers and knowing that every time you buy produce in there it's going to be organic regardless of the supplier Yeah. Or going to a whole foods and saying when I shop in the organic section here, I know this has been vetted, it's been tested I can trust what I'm buying here. There's lots of other reputable grocery stores I'm not just singling them out but there's a market for the market itself to police itself and they will rise.Yeah, you know where I think that's going to be particularly important at where I think that we're we're going to really take off is when the other cannabinoids start catching on when that research research starts showing that CBN CBG and blended cannabinoids because we will have already shown our community that we vet CBD companies and it's going to be the same companies that are doing the research on CBN CBG and we will be able to offer that very quickly to our customers as that comes to market.For somebody who is a former cheerleader slash digital marketer who doesn't believe that he should have get on a new medicine you are you are speaking like a doctor. And it is phenomenal. You're speaking like a researcher. What you're describing is, you understand the next wave of this. The majority of people don't even have any clue about CBD or anything else like that. But you're talking next level type stuff. Because the way that I envision it is the endocannabinologist will sit there and say, oh, my goodness, you have ankylosing spondylitis with ankylosing spondylitis. What I believe is that you need a ratio of THC of 10% CBD of 30% CBG of x and this is going to be the response you're going to have in order to be able to control your immune system. And we're not gonna have to put you on prednisone would not have to put you on infliximab, but Remicade or Humera, and the future of this is essentially real medicine. And when, because what I would like to do, I mean, when you sit there and say I love the fact in the very beginning of the show, you said, Well, I made enough money doing this other thing that I can focus on my other thing, I would like to make enough money doing my thing that I can sit there and do my real passion, which is research. I love research. I want to be able to sit there and say, Jeremy, I believe that I'm going to do this study, we're going to pay for it. We're going to look at what these different Endocannabinoids do in different diseases, and then I can go to somebody like you that can actually promote it in an ethical, honest way to say that this is the research that's there. If this is something that you believe that you need, that's awesome, but we've done our homework on the products that are there. And quite honestly, if it's OhHi energetics if it's elixinol that CBD line with CBD plus, these are all really good companies. Yeah, we need to get the word out. It doesn't matter who's putting it out there. Yeah, it's Not a competition anymore. It's a matter of let's start helping some people.Yeah, yeah, man, you're hitting on a lot of a lot of great things that I'm it. I'm wondering how how deep I outta go into this, but you talk about ethics. And I mean, that is a common thing that you hear in business people talking about, we want to do this ethically I'm to the point that if if we can't do it ethically, I'm not going to do it. And that that really becomes a complicated issue. When you look at you gotta pay your bills, you got it, you have to decide, do we make this dollar or do we do this ethically, and I just got to the point where if I'm very solidified in that fact of the company will grow if we are servicing enough people in the right way. And when you talk about doing that research Doing what you're passionate about, and doing it ethically. I just encourage you to stick to that. And things, things will happen to reward that in a way because we need that research from from a humanity standpoint, we're our, our society is so written with anxiety, and I mean, everybody it is, I hate to use extremes, but everybody hates each other because they're on this political side or that political side and I'm just tired of, of our society being that way. And I'm susceptible as well. And and so, I, you start sparking, sparking these emotions in me when you start talking about those things of ethics and what you're passionate about and all those things because, man, our country has, has falsely said that We we were on this righteous pursuit and and we've said it for a long time as a country. And honestly, I don't think that was the deal. I think we were in the pursuit of of making money. And so I'm hoping that we can heal as a nation and go back to, to this place of being responsible and helping each other out even when it might be detrimental to ourselves. And what I mean by that is, okay, I'm going to help you even though that's going to cost me money in a way where I can't pay my bills. So stepping out there in a way to help each other like we should be doing.That reminds me of the book Atlas Shrugged by Imran.Imran. Yeah.The definition of altruism to actually do something where you are not going to benefit. Yeah, that is the definition of it. So...Big shout out also since we've been talking about CPG to Dan and Kayla Wright from Green Sweet are a small company that is started just out of California and they're going around finding all organic land from California is as far east as Texas to plant basically hemp and cultivate before it grows too big so that they can simply go to CPG. Because they want to do research. Yeah. They want they are dedicated research and they're going to work with OhHi. And hopefully us as we go forward.It's one of those things this is like this is it's it's super cool that we're setting up this conversation because that means is essentially the first time we've met but it's crazy. How many people want the same thing. You want your kids to be healthy. You want to live a healthy life. Yes. You want to be able to pay your bills. Yes, you want to do all this stuff, but the majority of people want society to rise as a whole. Yeah, we really want to help and I think that one way that we can do this is to focus on the endocannabinoid system. Yeah, and just get everything back in balance. Yep, that's my thing that I tell all my patients The endocannabinoid system. What it does is just mediates everything to get everybody back in balance so that you're not over firing. It's not a big nerve that's setting off.Yeah. Yeah. The cool thing about that is, you know, Eric, you were talking about the feedback that we get. And yeah, I think CBD might be getting a bad rap for all it fixes everything. But the weird thing about it is when you balance your body, I mean, I was talking to somebody the other day that said that they had male male pattern baldness and they said, Well, my hair started growing back. And you could you could save what the CBD is not going to do that. But the thing is, is CBD is putting his body back in balance to do what it was supposed to do. So his body was just out of balance in a way. Alright, so I mean, not to not to interrupt, but a great example is when I see patients and they're like I've have I'm having weight loss. I'm having a hair falling out having this and that and then we can get to the point where you realize oh, you're not sleeping well, you're stressed. Your your thyroids out, and then we fix that. And then everything starts fixing itself. They don't think anything of that, right? They're like, Oh, well, we got your thyroid back to normal. Yeah, your hair is growing back, you're sleeping better. You're having normal bowel movements. It's all good. They're like, Oh, yeah, my thyroid's back to normal. That's cool. And we did that through nutrition usually, yeah. Because I'm not a not an endocrinologist. So I don't just you know, but we usually do it through nutrition and you know, change in lifestyle. Nobody thinks anything of that and, and then when we do the endocannabinoid system, ahthat can't be true, yeah. Guess what? Yeah, it essentially is like a hormone. Yeah, it's essentially it's a system. The endocrinology system is everywhere in your body. Your neurological system is everywhere in your body. The endocannabinoid system is everywhere in your body. Why can't it just come back to balance and cool things started happening? Yeah, it can That's awesome well I think that'll do it for our first podcast from the first studio our first our new studioWell we want to we want to end with one, okay. We always want to end with something with our guests. Yeah. So Jeremy tell us one last time about CBD takeout where they can go to find you where they can find you on social media the usual stuff and why supporting you supports the industry and helps people.Yep. Right on. So CBDtakeout.com. You can find us on Instagram CBD underscore takeout Facebook CBD takeout you know all the normal stuff you can find this if you go looking for us. We are a marketplace that vet CBD companies and provides the best slash high value CBD products and that has many different forms. You know, tinctures, salves, all that good stuff. And in one fantastic, easy to use website, one place to find that you know, going back to the the benefit of the industry is we're doing the work you know speaking to you customers. We know that you're overwhelmed with trying to find a good CBD product first you're like, what does this do? Second, why is it everywhere in the gas station or whatever? Third, how do I choose the product for me? I would recommend you go to CBDtakeout.com, we're doing that work for you and constantly reading laws, reading science, reading the research and vetting these companies to provide great products for you to use.It's awesome. I got one question for you. I've been looking for the best CBD toilet paper. Do you guys offer that?Yes and it's made of goats hair.No, no mo nomo hair.There you go. That's great.So and I wanted to add one of the things that you said when we first met to your website that ya'll wanted to add and the reason why I wanted to get you in and and Ken here together is soon ya'll like to be able feature educational videos. Basically walk people through the application of CBD and what to look for. Yeah, certainly. And we're about to launch a video series. It takes time, you know, coming from the technology world. I don't have video, well, I didn't have video equipment. I didn't have all these microphones and all this stuff and so acquiring that and figuring out what equipment do we need and, and hiring a good editing company and because if you outsource everything, you guys have probably figured this out, you lose your voice. And and so we figured that out pretty early that if we had a marketing agency doing everything for us and videographers and everything, then they were telling us what to do and they were chopping it up in a way that we didn't necessarily want to do. So we have decided to slow that down. Everything is done in in house and then we we will dictate, you know, hire out certain things but it takes time to build all of that but we are coming out with a video educational series. And y'all frankly, let us know what you want to hear we we don't want to just be talking about stuff that we're interested in. We're directing this to you guys and to educate, educate our customers, so let us know.Well, I'm going to offer this to CBD Takeout that the thing that we can offer Eric and I, which is science, yep. And so, you know, if there's, we have access to graduate students that look up a lot of articles. I just got into several articles today from our favorite graduate student, and she sent me some crazy stuff on the endocannabinoid system and autism and you just eat it up because then you start breaking it down. What I want to do is I want to say the how and the why that these things can happen. Yeah, for instance, it isn't that oh male pattern baldness gets better with this. I'm going to say, here's the markers that get improved when you take CBD because your own endocannabinoid system will decrease the inflammatory brain markers aisle 12 aisle 23, TNF alpha, TNF beta and it's done in animals and it's done in humans and they look at it and people go there's no research. No, there's tons of research. Yeah, there's tons of research, you just got to put the work in and we fortunately have somebody who's a rock star at finding this kind of information and I get daily emails that when I have my next job when I make enough money and I can do what you're doing into the thing that I really want to do, then I can sit there and spend all day looking at it but that you're exactly right. So our our, our gift to you, we want to make sure that CBD takeout is successful. And we want to help you in any way. So if your if your audience if your listeners ask questions, we want to make videos for you CBD takeouts and not for a product for you that we can offer some help for your listeners and explain different things.Yeah, yeah, fantastic. I think that'll be great because one of the things I mean, it's why I'm here is there, there are people out there that don't want to be guinea pigs and don't want anecdotal evidence they want science and frankly, I don't blame them and, and so that's one of the things that we want to get better at is providing hard science as it's coming out and being on the cutting edge of all the research we want to be leading with with that information.Sweet. Jeremy, thank you so much for hopping on the show. So you'll find Jeremy's fine offerings at CBDtakeout.com that is CBDtakeout.com also brought to you today by Atrantil. Go to lovemytummy.com forward slash spoony save some money. But you're giving me hands here. I'm just giving hands because I'm just like oh wow this is sponsored by so many wonderful thingsThat's right. Sponsored by love, sponsored by God, this is sponsored by the world, this is sponsored by...Yeah, I wanna I want to thank lazy Sunday'z Podcast for bringing Jeremy and I together Tequila 512 casita, you can find about find out more about tequila 512 at tequila512.com. And of course, the new website for KBMD Health should be rolling out pretty soon KBMDhealth.com. If you don't like the current site, you have no one to blame but me because websites should not be built by anesthesia providers. Shitty website.Right? So Jeremy, so this is this is one of the things and this is this little piece of advice to everybody out there listening. So I have a patient who's an extremely successful business person. And the one of the things he told me was that you want to know the number one reason why businesses fail. I'm going to ask you this. What's Jeremy, what's the number one reason why businesses fail?I would say lack of execution.That's much better than me. I said lack of funding. Okay, so he said, they never jump. They never jump off the dock. Yeah, there's essentially execution. Yeah, they never just jumped anf go well, Eric and I are jumpers and sometimes we don't build real build the best thing.It's a long way down. A really, really long way. Yeah.And then when you smack, then what do you do? There's a quote from Mike Tyson that that I love. And he said, I'm gonna mess it all up. I'm paraphrasing. Everybody's tough until they get hit in the mouth.Everybody has a plan until they get punched in the mouth. That's his classic quote. Yeah, I mean. Everybody says I'm gonna do this, this and thisNow, what do you do? So jumping, I'm also a jumper. And I've had to learn over time when you bounce now what do you do? And I've learned to think before I jump a little bit, man, when I was young, I would just jump. Here we go. You gotta jump. I mean, that's how you start, but then when you bounce then what do you do? How do you execute from there on out?Well the beauty of this is that I'm not a jumper by nature I'm a I'm truly like and it's funny when I think about it I'm truly a scientist by nature I've been Yeah, I've been a nerd my entire life. I've been in healthcare my entire life. And then you meet somebody like Eric and you get inspired and then we developed a product called Atrantil. And all of a sudden you realize that you become a jumper but I'm like, does not necessarily parachute but it's more Mary Poppins. My umbrella is science. Yes, well, I'm gonna jump but I'm pretty good idea that because of what's already been discovered what's already been shown, I'm going to land softly. Yeah, and I'm not going to do a dead cat bounce and, you know, just smack. And that's an old stock term, I think where people would sit there and say when the stock just plummets, it'll have a little bounce and that adds a dead cat bounce. I'm not trying to offend the feline lovers and thing

Bryan Bradford, CN, Sunflower Shoppe, Host of "The Healthy Approach" Podcast

Play Episode Listen Later Aug 1, 2019 117:31

Bryan Bradford is a certified health coach and nutritionist. He is also an owner of the Sunflower Shoppe. Sunflower Shoppe is a long tested pioneer of healthy grocery and supplement stores located in Tarrant County (Fort Worth) Texas. A US Army and Gulf War veteran, Bryan found inspiration to serve his fellow citizens by helping his family business become a stronger resource for health. Bryan joins the GCP to discuss the process of vetting quality products, the importance of certifications and COAs, the dangers of misinformation, bad labels and chemicals.The Sunflower Shoppe serves Tarrant and surrounding counties by having well trained staff, fully screened high quality products, and frequent open forum lectures to educate all of heir customers.https://sunflowershoppe.comhttps://podcasts.apple.com/us/podcast/the-healthy-approach/id1444435104https://lovemytummy.com/spoonyhttps://gutcheckproject.comhttps://kbmdhealth.comAnd now an ad from dad save money on car insurance when you bundle home and auto with progressive what is this where did you get this I'm talking to you with the hair yeah where did you get this good stuff so that's another nearly solid stuff progressive can't save you from becoming your parents but we can save you money when you bundle home and auto progress casually intrinsically affiliates and other insurers discuss not available in all stricter situations all right it is August 1, 2019 this is episode 19 the gap check project with your host Dr. Ken Brown I'm Eric Greer what's up can August 1 August 1 does it give a final become summer here in Texas because it's been really mild it's amazing we haven't I don't think it officially which I think official temp records in our area By DFW airport I don't think they've officially recorded 100° day in all July which is amazing if you're not from Texas that does not happen often I was listening to a Jim Gaffigan set on the way over here we talked about living in the Midwest spring just it sometimes it did vanish like louts it's April it's 30° the next days like 90 music well there was spring on every thrill hot pocket juggling hey so it is it is August 1 and for all of the several hundred of you that wrote in to let us know that you have liked and shared get your project back to the month of July for the contest for the signature package from Dr. Brown being a month supply about trying to heal and keeping the CBD thank you thank you thank you so much for the help the growth the the spreading of the word all of the winners will receive an email by the end of this week we were advised not to read off your names here because we need to have your permission which kinda stinks but I really didn't think that that's being new to to podcast and that's why we have a producer to make sure that we don't step on her on her feet that way Ron is like now you gotta get that kind of in writing so you will be notified the good thing is is after all of the success of the present especially in the art inside we don't have five winners of six winners six winter so it's awesome that's over $600 worth of giveaways right there that you make available to everybody so thank you again to everyone we will have more contests and more chance to share more opportunities and incentives on the good stuff coming forward but what a great way to to roll into the summer so absolutely so you have is our guest today guest today is the great Brian Bradford from sunflower shop and some flower shop if you don't know you live here nor Texas you are missing out basically they are they are the pioneers especially here in Tarrant County so it started to bleed by his grandmother run by his father down in Fort Worth they've expanded now they get a gigantic store appear in Colleyville right off of the 121 and you've given to records – on a super impressed is super smart guys certified health Coach got his own podcast called the healthy approach former military veteran really knowledgeable and I've given two lectures at his store with great turnout like standing remotely like people really enjoy going to stores and hanging out little lecture I does the first time that I've had a differing age population right and you know we always hand out cards to see how people react to its first time I got like didn't understand a word like oh I need to remember not talking to healthcare professionals all the bad I want to like redo it for her to drag her house and be like when he does redo this or catch maybe a little science as well but was also pretty funny and some of those responses were great lecture and they circled one so they just backwards on the net on the numeric scale which I thought was funny that all the time whatever doing those online, root reviews through Keith world somebody will sit there and say you amazing that it save my life and the one you calm up joke hey kid you change that formula, ruining the curve yeah it's not first place any five stars is that's funny stuff well out Brian in his store there was so much more than store which is why were having him here they their pioneer in the community what does it mean to choose healthy foods to have supplements that mean something to have someone guide you to something that it's going to actually benefit you that's why they have such a good turnout whenever you went there to get those lectures these people the customers and the clients that they have their date they don't shop there just because it's convenient place to go to they go there because he getting information on how to live better yeah I can't wait to bring about article with him also trying to was NSF certified I do and the polyphenols have been shown to augment athletic performance correct by increasing nitric oxide an article just came out that's Asada warned athletes about rise in ligand role use so the Australian sports anti-doping Authority warned athletes less than a year ago the ligand role was appearing regularly in random supplements so people are putting this in ligand role is a storm a storm is a selective androgen receptor modulator it's a class of compounds that have very similar products or similar properties to anabolic agents have less androgenic properties and so athletes were using this started in the bodybuilding world and now it's ending up in all these supplements and people to realize it so you have these pro athletes that are being stripped of their titles and stuff like for instance Joaquin Noah tested positive for was suspended for 20 games the best ballplayer emits mixed martial arts athletes that have been find money and had to sit out for six months or so and they swear that they were taking it on purpose and it just shows I can't wait to talk to him about how he vets the different products ago in his in his store and how many NSF certified products he has and so on so because that is exactly why we go to the trouble doing NSF I think really be going to what's the nutrition oh were going to fencing and that that is at the house but on my dates incredibly that is the last week of October or the lastregardless it's a gigantic nutrition conference for our registered dietitians coming there they're basically the front line of how we are reaching so many people 100% not sure that Brian will talk little bit about that because I pretty sure they have registered dietitians startled yeah I know that he is a clinical health coach and not Kunkel nutritionist himself so so this is why it's so important that when you have a product that you can not only to help with bloating not only do we help with the note G.I. distress different things like that bacterial overgrowth SEBO but you know we can show that it's NSF certified you knew the polyphenols as a benefit for your athletic performance yet that is so important to somebody who's a nutritionist dealing with clients could be athletes college athletes Olympic athletes professional athletes even right now Lucas is up in Kalamazoo and he's playing at high level you start applying IETF's and they have banned substances that are actually listed there so just that it happens even a really early age so NSF certified optional until go to love my Tommy.com/spoony SP 00 NY and you get a really big discount on this in a minute challenge everybody to commit to do this because we want to get a little bit of a pusher and make sure that we start promoting the NSF certification the polyphenols and the overall digestive relief on your safety and your confidence is critically important you start whenever we started the company you made no bones about you want to make certain that you had a product that worked to make sure that she had a product was healthy it featured polyphenols but at the same time he didn't want cost to be an issue you wanted to be in excess or I'm sorry a barrier to accessing you also didn't want anybody to not be confident what they were choosing was it safe that's funny because eventually have to write a book about the whole process because like when I look back there are some really funny moments like for instance when we were trying to figure out how to get the we knew that Cabral chose you to be our main ingredient type so we contacted a company that we now work with regularly in the fantastic company but I got some terrazzo in the because I'm worried about everything so I better make sure that this is exactly exactly what it is so I called around if you want to hear something funny stay tuned so I called around and asking labs and the like now as it turns out there's only really one major deconstruction lab it's in Kansas I got hold of the owner and I was like hey I need you to freeze I was like no problem send me some of the bar can all do it I would send you some of the bark is a gas chromatograph on if we get one major spike reducing that's that but I can only do that to a comparison just you watch way too much CSI several white bags that tell us what that is but he comes back it is just like out goes actually we have to compare to get something no gas chromatograph it's it's a fingerprint of the molecule right and we did that episode on food pairing to remember that all yeah that was a gas chromatograph you look at different foods with similar gas chromatograph's and the aromas augment each other and as a way to do food pairing we do that we shut Patrick early on but this is this is an example so I send it to them and I'm like I got a flat on Argentina get some tree bark just go to chop it off and send it so that we went through a lot of trouble to make sure that it was everything was pure but I was the funniest thing you watch too much CSI well and and then beyond that whenever you and Brandy or step in interest to try it out because every single thing you've ever turned out the all of always put yourself through the test first and we learned that through without even knowing that but we learned that through Dr. Dryden right out of Kentucky he's a fantastic guesser neurologist full bird colonel I believe he's an obscure himself and we got to talking that there is a Helsinki rule that if the researcher is willing to do it to himself and it's not questionable or anything then essentially you're saying no I believe this is safe and here's my data with that so yeah everything that we've done it's always been on me and Brandy first so so did you have a brainy phone call one time we were at the time this two different types Toronto Roger Blanco and abrazo Colorado which one is in 20 oh Colorado so the blanket was much easier want to get that act as a molecule in the cold your Hindi which can be a stimulant and it's been reported to have different effects including improved sexual function and things like that but that's one that nobody can find in fact that was well when I did Melanie Avalon's intermittent fasting podcast is check that out right the first one I did it twice with over the first one I found her in website that she tried to make out trying to at home and it did work and work and we actually had a long discussion as well it's because it's a totally different type of molecules because it says Toronto doesn't mean that it's it's this dongle easy to get Colorado not not and so we got the Blanco we will try to dose it out what what we thought it would be to state that Brady had to go to a meeting and I dumped the rest on the sink night and then one of the employees came back say the sink stopped up like what I realize that did say it'll just congeal in water and I went so I called up I'm suggest our children water coke out of the once you have a bowel obstruction to have explained that but virtually nothing happened but I member when we first launched also so we called up with some abdominal pain and I worried I mean I took a bunch so I just ate a whole bottle just make sure wouldn't cause like an obstruction or anything patient call back on fine and hassle – it's going well I got time 60 capsules sit in my stomach let's see what happens you like a Kobayashi of the eating contest but that being said we did understand this is it that reckless we do understand the science of this the cool thing about these polyphenols is that they are poorly absorbed so they stay primarily in the small intestine and there have been studies that have shown that the blood levels are essentially negligible but then when they try and find it imprudent find less than 1% of the original molecule which means it's doing exactly what we needed to do goes through goes to the colon where your bacteria break it down into all these beneficial molecules like euro with and things like that which help with overall my coffee G cell turnover carrying a very antiaging then your Litton is if you done any research and you really try to figure out molecularly what you should be interested in your lesson should be of a good trigger word I think over time it's can be more ubiquitous or more prevalent as people begin to talk about what you can do to be as someone is actively antiaging I totally agree the only thing we were talking about this people become O'Brien the only thing that I don't like is that when this research happens everybody's trying to find their angle and so when Morgana was in town talking about this she's a PhD that we work with he we got to talk about the different metabolites in how people try to figure out how to make these metabolites and turn them into drugs or turn them into a new supplement and it just doesn't work that way mother nature knows how to do it just can't completely manipulated like that now you mother nature works in its whole form I made it we've seen that time and time again we we reference that with that even even marketed drugs that are trying to compete with over-the-counter supplements specifically melatonin we go back to the days of Rozerem when they tried to isolate and make this basically Roseann was post to be a super melatonin that was going to be 14 times the binding affinity of of endogenous or regular melatonin turns out it didn't do much anything you just separated a lot of bills that your wallet didn't sleep anymore it's me that's a bit that's frustrating to see this when we have a lot most pharmaceutical start from a plant-based something she made a Mormon weldment form and the agent Jacoby reductase inhibitors the cholesterol medications aspirin and most of them start or what GW is trying to do now with spinning down that CBD specifically doesn't work nearly as well they can charge you how much do we hear that someone is being charged I don't know exactly but it is tens of thousands is what I was told because it's such a rare orphan goes in orphan drug status duvet syndrome and Lenox Gestalt which is unfortunately a severe form of epilepsy in children small gripe and happened to notice that I didn't read this before did you know okay so upfront for those you who may not know whenever you have something it is prescriptive that may have addictive traits then the FDA technically awarded what they call a scheduled class and schedule class I they basically say highly addictive but has no medicinal purpose there's a handful of things that fall in their people usually a default say heroin etc. and you got to which is most of your potent opioid stent nail cocaine etc. have some medicinal use but could be highly abused or had abuse potential as always down to schedule control five I saw on the label for GW's new release that they have a C5 on there which it really hates schedule it's not addicted it's the most ridiculous FDA's allowed to call schedule five which is like drinking water right and then they had all that coming due or just talking six months ago were people being arrested and saying you can't do this it's addictive in all kinds are so much misinformation out there about CBD is think about that they're trying to trying to pair this this connotation it that there's a little bit of fear and if you understand scheduled medications are trying to say that there is an element of addiction associated with and I spun down CBD isolate its insane it is so now now they are there quite worried about anybody even coming close to pairing up a disease claim with the with CVD and this is from the same institution which has allowed the food products that you eat to be sprayed with with Roundup doesn't it does not there's just so there's so many things were heading and a lot of wrong directions which is why we like having just like Brian on we can talk about how shop like some Photoshop can really help out guide you in your food choices guide your supplement choices I mean just look at CB dealing one of the reasons why we teamed up KPMG health CBD we got that certificate of analysis we really want to make sure that you get what you're doing so CBD my wife she owns a wellness studio called body body balance wellness and its indicator and she has all kinds of different people to come to ask questions and she gets asked about CBD also just yesterday she came across an article where yet another celebrities endorsing the use of it so this is it coming for mazes and coming from my Dr. Brown but Michael J Fox is apparently become part of one of the CBD companies and specifically because of the effect that CBD is having the positive effect it's having on his Parkinson's which I found interesting but not surprising knowing how we think that the Indo cannabinoid system strikes a balance between our nervous and immune systems it does make sense knowing the Parkinson's has some elements of inflammation and a course you have the uncontrolled twitches and whatnot would ask which of course would be the your neurologic complex of our bodies, running out of control he's found some elements of improvement in his life by making CBD a daily part of it so basically treating CBD for him and in his words is a micronutrient oh really isn't what I was really really yeah me last week show we did brief we covered three articles but one of the articles we did cover was on the micro biome affects people with Lou Gehrig's disease and how the micro biome has anti-inflammatory markers which which does this order talk a little bit later about how complex these and a cannabinoid system really is and how a lot of things can be affected but that makes total sense and I want to see at some point that were having CBD catered to in you right have ready so scared to say diseases but CBD catered to something with a different terpene compound turbines are the essential oils in it or different flava noise component because we considered okay what are you looking for this for what I have I have a neurologic process I got MS I've got Parkinson's like the circuit we need something to cross the blood brain barrier more so let's try this particular one with a higher content that's right think the sciences had yeah and it's it's put the cart for the horse because you can't make your disease claims or if you like that but at least we can sit there and go okay this makes sense why that's actually happening you know if I was in Norway we can pull that off you what I'm say was that debt Texas oh yeah so today I learned on Reddit sounds good yeah that Norway people use the term Texas as slaying for crazy it doesn't hurt a person but a chaotic atmosphere or state of mind so saying a party was totally crazy in Norwegian would be debts of our help Texas which literally means it was Texas and I'm looking at the comments of those people from Norway going up we do say that is awesome I I think it is also the green to that point it would be that would be pretty pretty amazing what you know what Holly what what movie was that I think it was Independence Day when the aliens were coming down and they showed how different people were panicked but they paint over to Los Angeles and they were all going crazy and welcoming the aliens I could wait to be abducted it's almost like if you want to join us have like a weird connotation Los Angeles is kind of said yeah that's that you could say it's it's only Los Angeles or Texas is now apparently just wild crazy and wild about Israel so I'm not sure helping the families we have in no way right now but the now that forgot his name but my dancing partner when we are rude to the bathwater 000 she's Norwegian yes yes it is pretty nasty yeah he took control of the as a live band and had them play what he wanted them to play those Norwegians there so Texan yeah and I he was he was great he's hilarious so we now with Brian coming on here in our next half-hour old and have a good 90 minutes this guy this guy's got incredible experience long before he decided to get into running the DSM flower shop which he has your which we referenced in locations in Fort Worth often can't buoy your location appear in Colleyville and got another one it's a smaller version over on heritage trace the cool thing that I liked about it is as they've grown they just simply found that people looking for a local answer that has real guidance to get people into the store so what what you think it takes for a community that may be somewhat isolated to began to find out that they may have better access to this type of nutrition and where they don't to turn to just the Internet over the Internet away because if you look at like the span of where a lot of the healthy shots are its economy migrates from the west and Canada tapers down almost a a diagonal line into Texas and as you go to the southeast until you hit some some populate your supply. Parts of Florida you really don't see you don't see a lot of sunflower shops and stuff like that why is I've never really thought about him for when I imagine the West yes because that becomes her but Texas is really embracing it right now sure and a lot of people they want to go to their doctor and they want to talk nutrition and the doctor is busy doesn't have time doesn't maybe doesn't know a lot I freely admit that I'm continually learning more and more about nutrition little account locale even just think in your life how you changed your thought about what the importance of food is any outside of of medical school the growing up in Nebraska me going up in Texas at first I read anything much about us came home and ate and I have a lecture change my pocket I go to the convenience store and buy something but it's not like that it all for me anymore and then nowadays when we think of you'll you'll hear okay this year so-and-so is released the most obese states of the most obese cities are the least healthy whatever unfortunately this statement immediately comes to mind is first Mississippi or something like that and then it is quickly followed by Alabama Louisiana is a great topic to go over with Brian is a social economic is an education thing is it possible to eat healthy on a budget is it possible to to do all these things the highly processed foods that mean we talked about this all the time I think Netflix just has a new thing called fat something I'm seeing it and I'm assuming that either I was scrolling around with Carla try forgot something to watch and it does get into the fact that 30 years Gordon 1970 I think there's a 1.5 million Americans with diabetes I would like 30 million only some crazy jump that just happened under our noses and we didn't even notice it so that is really a lot to talk about the Bronx on policy bills I don't see the business side to see him as a healthcare provider how do we merge the two where would you go with it it's really really cool that's an unacceptable level and rate of growth is just not enough time for many people to have her since we said Carlsbad I'm sorry fat bad maple starter really double down on the carbs and you know the ass oil started taking place watch watch less which episode I really appreciate all the emails about Amsoil where you can guided some of those comments are pretty pretty funny white liquid and be back in just a moment with Brian Bradford of sunflower shop and that of course the healthy approach podcast we will see you here in just a expenses blue yellow pills to charge your sex life are you thinking about what we can promise you the same results for three paying $20 a pair for the other path you're getting taken to the cleaners same results for less than three dollars and $16 account for the same results right now for blue or yellow pills 23 and keeping more than hundred dollars our pharmacy prices right now your 40 4 PM and qualify for free setting over pain, right now 186 473-800-2186 473-800-1864 73 800-218-6473 fast-track student loans can get your student loans out of the vault stop any wage garnishments stop collection calls and stop seizure of your tax refund give yourself a break to stop the stress and get your student loan payments down to as little as $25 a month based on what you can afford to pay 800-709-4395 800-709-4395 800-709-4395 800-709-4395 now you can fly anywhere in the world and paid discount prices on your airline tickets flight to date alignment harassment to read or anywhere else you want to go and pay a lot less guarantee quality international travel department right now low-cost airlines grade 452-107-5800 452-1075 that's 800-452-1075 although we are back in his 19 year with Dr. Brown your host and I met Eric Rieger today we have a special guest this is Brian Bradford of the sunflower shop here in North Texas Brian how you doing I'm doing well thanks for having me on today thank you for coming down and make time with us of course you are now the host of your I guess somewhat recently launched the healthy approach podcast have a healthy approach but because we distorted that your recently to sober try to get kick started to get into this environment this much you guys are that is awesome I know that when can I were talking last half-hour about whenever he came to do the two lectures up at some flower shop now a course your shop is necessary close to him because he's on the other side of the Metroplex right off shop there for years I was not surprised to turn out the first think and said it was that was amazing the engagement was real direct the room yeah well I think that is what's really cool so you actually have on the second floor a full lecture room old 80% 80 people comfortable 80 people I was just shocked both times I went completely packed and I what I like is the sense of community how a lot of people make this the regular outing they want to learn and you you help them learn and you were asking last half-hour how do we go about getting people to become healthier will it all everything comes on education but it does and that's what we pride yourself and as stump our shop is really trying to give people all the education and let people know who's in their backyard having a lot of people don't notice people like yourself who are open-minded to both medical and alternative nutrition and that's huge because people are seeking this information and people like you got Brown coming in and doing your speaking engagement such a blessing for a lot of people both certainly an honor in your you get out the community and you get to hear little bit what people are saying and after the Q&A is so long because people are questioning oh boy yeah and do that and then you start realizing oh my gosh there's some there's a little mismanagement going on out there know my doctor wanted you X, Y, and Z them like why we try to quit doing that in the 70s that's weird yeah it's about keeping up with the research and I know you're someone is a pioneer in that well the one thing that I'm like very open to I watched a Kimber what podcast it was a Freakonomics Freakonomics podcast had a whole episode on medical reversals and you realize I fully expect that what I'm doing today should be somewhat tweaked and could be a little wrong and may be misinformed just like retirement when white low-fat hi card we became sicker that's right and that was that will spread like crazy you know where people do this I was there is a podcast a listen to this morning holds all bones and it's the doctor that that kinda talks about medical misinformation possibly in her husband it's kind of funny and they were talking about alkaline water about how people want to drink alkaline water and she would just go back over the science of it they do a whole episode on medical reversals also and it's not necessarily that your doctor doesn't know what's going on because most of the time the doctors figured it out for instance when Eric was a drug rep for Xenical when they said that you could block fat and lose weight it didn't take long for the medical community to learn something yes they were introduced to add soil so as it turns out he created a lot of in a leakage of oil could you can digest your fats and yeah the warning was to wear white pants with that right warning on the bus that was at that was the corporate response type hands you're not sick it's completely natural that we can all just realize were losing weight is it's only then he is really only 20 years ago I mean that Danielle Ally still would like still out there as far as I know has everyone Walt Walmart had pallets about stuff like crazy has a fat blocker and that's not that's not the source of your problem it's it's it's it's it's unfortunate I did that start out with potato chips or something this night it did when Xenical was like will board this is not going to around let's just sell the which is still being treated so that both Frito-Lay and all the big giant companies they got it they called olestra olestra and everything in San Antonio was in medical school and a DJ on the edge I was driving and he was like Joe not eat these Doritos is horrified euro detailed graphic incidents about how it just he had no control the student realize was happening and is through upward summary stories about that yet people just started with potato chips on their people come in and say hey these things really upset me big time you know I need something else my bowels back in order again crazy what's crazy how fast they pass the buck to because it did start start off is the generic name orlistat and then they just barely tweak the name and called it olestra and move it into large consumables we just want warm at all now that is going down a surprise attack what you know with some flower shop I find it to be an incredibly awesome store and it was refreshing to me when I first did I discovered I was doing we had Dr. J. Anna was doing anesthesia with him that get here Bedford and then I drove along I saw some flower shop looks like a place I like to go to so did you think it was a floral shop though the very first time I didn't honestly I didn't really know I think this is right when the iPhone pretty much had made its way to me and I was googling a place to find a healthy snack and I was it down in Bedford and it came up with some flour shot you can with some flower shop and when I just sawed off in the distance a light I guess at that I'm headed now it's right but a course I yell or not that far from ignorant traditional big chain grocery storages setback behind you so I walked in and immediately I could say okay this place is different and and there's a reason why it exists and it's a lot because of what you talked about with the change in fat content and how people moved over eating different foods it forced people to have to find a different answer and so your grandmother and your dad started this several years ago in 1970 there was a reason they that long ago get into something like this and that is the aspect that it was considered broody right hours herbs and supplements go but no my grandmother started because her sister was dying of leukemia and just all the horror of course you know what treatments were like back in the 60s for the top of this you know Jesus was looking for better ways and she came across some of the pioneers like Adele Davis and Linus Pauling and so forth and said hey baby or something to this we need investigative mordant so that's really what she sold her moving company with that a moving company at the time sold but gamble everything on a subpar shop now why the name I can't tell you why the name all we know is that you love some flowers so is probably where it started out there but that's really work began in 1970 in Wedgewood Texas you know in Fort Worth area and then it grew to now where were at three locations three generations later my brother and two sisters now run the all three locations man it's in its awesome is something one of the things he jumped at me right away when I very first went in there so it was it was probably not inoculation into a store the sky like that and where you go to a big chain they have to identify if they identify the foods that are there okay and or and or non-GMO and rare we don't have to worry about that because everything and there's been vetted they're not going to put a crappy product in the store so first like the wonders of Abel that's okay this fits what I'm after so what what you think led her to decide you know what I don't like what's offered everywhere else and not only my going to open up my own I'm probably gonna carry a lot of things it really is not comfortable with or doesn't know how a lot about how did she decide and then you fallen your dad fall into the idea I like educating people want to know about the selection comes out that's where it really started was really based all centered around education okay no course we didn't know was much we do down today but it started with the education of just saying hey let's learn more about the body and how you know certain plants and herbs can interact with body the best we do back in the 70s is where she started but she wanted everything is clean as possible she didn't want anything to do with chemicals and in anything that's foreign to the body and spirit that way she was really want to keep things clean as possible now today health is relative to the person she notes that we got something with it for everybody what's good for one doesn't mean it's good for the next person and that's where what we pride herself and in consumer like yourself walks into the store we ask a bunch of questions we want to know little bit who you are where you're coming from what your mission goals are and so were gonna do our best to try to isolate you know even though we may have 20 different vitamin C's on the shelf which one is best for you everybody's a little different for each reason summary very first launched trying to heal and we were talking about where all that we wanted to take it just ideas how do we how do we let people here know I gained a whole new respect or what it takes to get into a repeatable store because we talked about trying to let some flower shop on the first longitude and yellow light well we need to see why you think it works what's the story behind it we had to submit all of our ingredients yell called back ask questions the exchanged information that way it was an easy and it was worth it so basically it filtered it keeps out the noise and it put innocently woke on this we think so but puts in the solid product that's available to your well beyond customers or clients well it's a reputation you know we we want make sure that when you're pick up a product simpler shot but it's a good quality product to the best that we can bet it yeah that's that keyword that because that's what ends up happening with that these big box when we we always reference the Wall Street Journal article that described how when they did DNA analysis then we show that 70 over 70% of the products that I have what was on the label a new study just came out on melatonin were the range from nothing to 500% of what was on the label and so it's still happening all the time all the thing it is it's all the time and here we get hit which all these companies are always want to come into the store and it's like you said it becomes low noise and you gotta be old have some kind of system to filter that down and figure out what what in the product is a good for you no good for you it's got her chip is attested for heavy metals in bold pollutants and all the toxins we get to know those things it's important to try to get the best quality product to the consumer and that's I mean what were talking about that I did want to hit on something so when somebody maybe doesn't have the will to say really air water like a really expensive so were an arrow on in LA ditto like celebrities like to go there and it's note similar to what you have but I think it's probably little pricier jurisdiction only mild horse so how do you that like this put this much work into it and still make it affordable so the people become in our system we got some great people the store really do know exactly what to look for what to ask for the questions that we need to know from manufacturers now on my side of things all even fly out to the manufacturing plants I want to see what whether sources are coming from how the processing is much as we can make sure that the bathtub is clean going to make sure the colloquy was possible Eric always there always places drugs and put one of my patients asleep that he just made that propofol this morning's bathtub the flash works real good you don't know you boys your insurance is bad little humor takes away the head to bad food helps everybody but it is it is it really boils down to the best quality get good there's a lot of junk out there there isn't special I know you're big on the CBD side I mean look how many CBD companies are just popping up left and right we get stores popping up all around us you know how are they now they really betting what their carrion and make sure it's good quality product is an unfortunate since this is just the just another thing that just cannot come in around in it we just have to do a lot of educated speaking of educating Brian whatever we do the show I was trying pull an article and now that you brought up CBD limits I about this article that is really interesting because it it hits home with me so dear have anybody comes and complains of the belly issues got issues that is not complaining about soil probably about 3040 times a day so in the this just got published in the Journal of pharmacologic sciences this looks at the role notes can be a really fancy title all eventually get to the point where it's like this is really what this means but it's exciting for me because it's in my world the role of cannabinoid signaling in the brain over Rex and grown induced visceral anti-nociception in rats fancy title basically what what's going on here is that if anybody's ever had abdominal discomfort you been labeled with irritable bowel syndrome then you know that you have what's called visceral hypersensitivity meaning what they have shown is that when people have got issues like bacterial overgrowth see Bo IBS irritable bowel syndrome that they can inflate a balloon in a normal person and this is been proven in humans and animals that one person at the same when one person like yeah there's a balloon in my rectum I can feel it at the other persons come off the table in pain because the direct correlation of the brought date of the gut brain access actually get that person to feel the pain more we call that visceral hypersensitivity so what they're looking at here is that these guys were looking at two hormones correction which is a fasting hormone and sodas hypo cretin to neuropeptide regulates arousal wakefulness and appetite Eric and I were doing a five day fast one time and basically I made my whole company do it in almost all of us like middle the night on day four day three I don't remember what it was but we were all up just run around wired wired yeah and that the old Rex and is this neuronal peptide which is kicking in man and it's because if you go a certain period of time an evolutionary standpoint it's time to go until something in feed go feed the village that's right and so this all wrecks and does that and what it also does which I was unaware of in this is it actually decreases your abdominal perception of pain very fascinating to me and then growling is the hunger hormone we always badmouth it but it actually also decreases the perception of abdominal pain as well so they were citing prior studies with this where this was new to me but we've got these two direction and grown which do this so now it's well known that CBD cannabidiol has been shown to also help with bowel hypersensitivity and it was I don't my practice as he does benefit all the time I put everybody on trying to in CBD and we just get overall benefit for whatever is going on does your belly feel that yes it does what we've always kind of thought will maybe it was an interaction with the receptor CD1 receptor is in anticholinergic the end of cannabinoid system is so complex would really, learning that attract what this article did is it really it was really cool it theorized that CBD had a direct effect on erection and growl and so they set up an animal an animal model to try and prove what they did is they took various rats and they had these pain perception techniques which were too cruel but not very nice either but everything I remember our animal study it's like doesn't sound Nido sound good to know they used a CD one and CD two agonist meaning they were able to give a molecule to turn on CD wanted CD to which are our Endo cannabinoid receptors then they used synthetic correction and growling to actually kick those out finally they had CB one CB two erection and relevant antagonists or blockers so what they did is they could turn your enter cannabinoid system on that you turn it off they could turn on your grill and anorexia and they can turn it off so first what they did is they blocked the CB one receptors and then they gave the hormones of erection and drilling next they gave a CB agonist with no hormones and then third they just gave the CB blocker less ICBM in the undercabinet system blocker and checked central rocks and Negron levels so what I thought is pretty interesting when the end of cannabinoid system of the CB receptors were stimulated this actually induced improved pain perception from colonic stretch so we have a mechanism of action we can't make disease claims but now we've got a study that proves that when you stimulate BCB receptors then they can tolerate more colonic stretch then the hormone effects were severely blunted when the CB receptors were blocked okay so when they gave Grell and Anil Rex and it didn't work unless you have proper CBD levels so basically we can say that that ECC has health is paramount to all Rex and a growl and performing their job absolutely this is the first time it's ever been associated that this would suggest that that the CB receptor CB wanted to be to they can actually mediate the correction induced effects on paint okay we have a mechanism of action that now says oh it's modulating this hormone that helps out a first time somebody's going to this depth what was interesting is growing was also blocked by CB to but not by CB one so it's just really complex okay they go down some rabbit holes I'm trying to really supply this but it is geeky geeky geeky science so what to suggest is that CBD is involved in the hormone benefits of pain relief in the bowel super interesting because many people believe that CB to is in the periphery but there were showing is it's also the brain affecting drilling that is amazing I know it's amazing because we we don't do complex but you don't want to simplify it too much ego this is all that we know so they're saying no there's a lot of CBT receptors in the brain and its regulating other peptides and hormones so this shows a very intricate interplay of the under cannabinoid system and how it can mediate central hormone effects so in layperson terms if you have hypersensitivity got it if you expect if you want these people that when you bloat it hurts really bad because we don't have pain receptors with stretch receptors so if you have bloating due to bacterial overgrowth or irritable bowel syndrome then you may notice an improvement through couple ways you can check the erection up by fasting so that was something else think about Mike that we should do more long fast right or prolonged style fast if you're low on your own endogenous Endo cannabinoids then taking CBD may increase these hormones get you back to balance and finally if you're not in balance than these other complex processes are knocking work as well so just really complex but I thought this was really interesting that I can say oh I have a reason why you feel better and you don't hurt as much when you're taking a good quality city Sony really I think the take away here is nothing in the body is is in a vacuum they long ago you use all connected everything's connect that's right and it's like whenever you take an ad and anti-inflammatory doesn't just go to where you heard it circulates everywhere you just notice that it's helping you or taking away the pain that Harry with the same thing is for the E CSR Indo cannabinoids system it all needs to be healthy and so balanced yeah it's all this really says is you have to have a healthy ECS if you don't want to have too much pain that's not what you're benefiting from you benefit from extra pain so Brian when I deal with doctors and I'm talking them especially traditionally trained doctors guess what neurologists intro medicine will be like how there's no science on Mike there is so much science I will ship every day there's so much but you gotta like knuckle down and read articles like that okay there's no science that says this cures this disease right but there is science it says on a cellular level this is happening which is probably why it might help or may help or could help or whatever term you want to use because unfortunately I think in traditional medicine which is why they go to sunflower shop to get some advice to get some education most of the doctors or just the busy the referring to either what was the last conference I went to which if you're been on its drug rep sponsored to the hilt and they're just kinda being detailed on what the last person can explain to them or their doing things out of habit so a lot of this there's not a lot of time to get really passionate about this one thing I will learn deep into it and then you start realizing I've got I've said this before but anytime you want any articles I've teamed up with a graduate student and we share this Mengele account we can love it me and I got we got over 10,000 downloaded articles I had to laugh because it's like you know I will never get through that now without talking like 1930 that's right I'm up to date stuff. He published all the time and people say unless it makes it to its sensationalized on good morning America or something most people don't ever hear about a lot of this cool stuff I'll call up some of the scientists and elders before that I read their article on like fascinated everywhere you go with it now oh they lost their NIH funding and they had to close the lab or whatever that but yet the research is just amazing and you know some far sharper lease we personally for sure we try to network with a lot of doctors because we know they don't get time to do those things and that's why were always trying say hey send them over here will educate him or not there to try to sell them something is not were not commissioned were not trying to push supplements on you were to try to educate you when the doctors don't have time to do that is like you said it's your busy the busy so it's important to really get as much education can that's what we pride yourself on our whole steps that way yeah it's the you know it's the frustrating thing to see somebody come in with a whole bag of supplements and it's all from Sam you know I worst enemy Dr. Alden Oprah every time they speak about a supplement we get a flood of people that come in the store and 90% of the time we got a tell of this is it for you this is they think it's a one-size-fits-all just because they said it and so it's a love-hate relationship is for sure but we have to really we turn people away more on supplements that are being touted or marketed from certain celebrities especially sure you know because it's not is not for everybody and that's what we want to make sure that was really one of the problems that we run into when we lots are trying to lose it is so different than the mechanism so unique very similar to the amount of knowledge people have a CBD that when we go to like we go to the IFN conference you know there's a lot of really good functional medicine manufacturers but they're just kind of moving around similar ingredients into whatever fancy name you have if you want a white label that's right so one of the big hurdles is to first educate will know this is the problem you have we can fix it because of this this is doing in a completely unique way and then know the answers I Marta I Marty on a probiotic I just spent 20 minutes explaining about it but I have a searcher to think about the early days of auction deal whenever we number the sum of the first marketing material was explaining what type of bloating because people didn't even understand say people several people didn't understand what we meant by this you true bloating and in and being mediated by methane production or whenever people thought that John Teal would cure all constipation we found that when none and it's actually permitting induced constipation it has actually nothing to do with opioid induced constipation so I think even so Dr. Oz had to go in front of Senate committee yeah yeah, taken to taking the task of blood very well they sure did mean it's sometimes they just talk I don't I really don't know how show operates you know how the elbows products get on the shows but well it's I think all of us in this room realize that like if you're a mean just talk about something so anybody is regular and I'm pretty sure I'm not wake up over the night before I sit with my kids on the bottom are then this morning going over articles which was about on the Reddit looking at the euro Denmark: brings Texas you know Dr. Rogers shows up and he's got people just himself in a dry Teleprompter so there poor guy I mean I know it's not like he has the time either to be reviewing all this literature and stuff that's true but you know it that's what sorta gives our industry a bad rap sometimes because now you got 50 people who were never taken are now taken something that they may really not need and that's technical subissues I get it so well so it's an educational issue I know exactly when Oprah or Dr. Oz says something because that'll be the first to be the 10th question I get that degree and I'm like okay Mike you have to watch the summer have to watch these episodes just so I know what that's what we have to do to get by customers in a day in the Nelson were on the watch Dr. Oz at night to figure out what he was saying and why you saying that word that information is coming from that's exactly right yet I am this celebrity status that will bring something that did to the taillight to the forefront and it happens in all industries all details before Michael Jackson had his issue with propofol I didn't have any patients who ever knew what in the world I was talking about but probably what would you say 25% 50% of the people that we have before I put them to sleep for the four procedure they say oh the Michael Jackson sauce every every day and it's not their fault but that's that's the impression that they got inserted that celebrity influence is real well they and it's not just that I mean there they sell advertising all the stuff so they don't just stop at the show me that he's got his magazine's gesture so this is a big massive machine I was talking to Eric before the sergeants I was in the middle of watching this Netflix special boot the big hacker something like that were chasing well it's it's all about how Cambridge America manipulative Facebook does is why Zuckerberg had to go in front of the Senate committee and all that right you just like oh my gosh we are just little ponds me to manipulate us in that so many different ways so many ways that's so true and that's why it really boils down we start our level is that our main goal is gotta be to educate the client you know as much as possible and you in the end of 5 to 30 minutes that we got spent time with them on the floors try to give as much that's really that's really what I want to get into is how the sunflower shop and stores like it because you we are just here in Tarrant County drink with the sunflower shop but we were talking in the last half-hour why is it that tell you he almost see from the West Coast and almost in a diagonal line down to Texas the proliferation of stores similar to yours and then we move over to the East a few states and just don't see them quite as much and it kinda correlates with where we say some of the worst health is found whenever we do no an analysis of which states unfortunates have the highest rates of obesity etc. there's there's a service that you're providing and a couple other industries are providing that are born out of the lack of good information in there trying to find good places to get good products on talk about whenever we get back your Brian I got to where he got what sunflower shop is doing to fill those holes in the community and foreclose out don't forget like and share a gut check project go to get check project.com you will go and connect us there let us know that you have liked and shared in course you can be entered into the next contest don't forget if you want this last month will be emailing you by the end of the week seen on this is the only 24 hour take anywhere platforms dedicated to food and fun clear spoony this hour from Townhall.com, the best way forward on healthcare Democratic presidential candidate Joe Biden says it's not the plan being offered by rival Pamela Harris there will your paycheck during last night's debate Harris criticized Biden healthcare blueprint for everyone in America you are in your own people people's access to healthcare in America running for president cover send candidates on the CNN stage last night 10 others debated Tuesday night Heritage foundation's Genevieve Boyd says there's one big issue working against any Democrat hoping to unseat Pres. from Mary Ron when people are feeling good about where they are what variables one. Building background want to be able to deepen their family the son of Osama bin Laden said to have followed in his late father's terrorist footsteps is reportedly dead I'm so bin Laden apparently killed sometime in the past two years one person was killed five others hospitalized following a massive explosion and fire in Lincoln County Kentucky overnight natural gas pipeline blew up a Navy pilot still missing after jet crashed during a training mission yesterday over death Valley search for the pilot continues on Wall Street to shower the Dow is off about 72 points the S&P ahead 11 NASDAQ up 66 more on the stories@townhall.com I never forgotten apparel is more than just a premium women's and men's clothing line it's a movement to remind us to where American-made and serve those who serve us our heroes never forgotten apparel gives 20% of their total sales to nonprofits that support homeless veterans and off-duty firefighters and 50% to individual veterans and firefighters in need nationwide checkout never forgotten apparel.com use promo code Matt and ATT and get 15% off your purchase why have thousands of aspiring authors teamed up with Christian faith publishing to publish their blog because Christian faith publishing is an author friendly publisher who understands that your labor is more than just a book we provide authors freedom and flexibility throughout the publishing process professional book editing award-winning design and some of the highest royalty structures in the publishing industry and is always you will retain 100% of the rights to your book I was looking to find a company that I could trust one that assisted in the editing process completely Christian faith publishing will publish market and sell your books in all major bookstores and online booksellers as well especially Christian bookstores call for your free author submission kit 800-978-4812 800-978-4812 800-978-4812 that's 800-978-4812 Dr. Kim Brown here a host of project with my cohost Eric Rieger I've seen in my practice that I'm trying to is a whole lot more than just a floating product yes it is a whole lot more than just exploding because of the polyphenols that you find in Alicante what are some of these polyphenols do these polyphenols help you have more energy and polyphenols are great sounds like it's helping a lot more people than just loading go to let my family.com/I start the second hour at episode 19 get a project with host Dr. Ken Brown Amir Krieger and we are doing today with Brian Bradford of sunflower shop real quick before you get too far don't forget love my Tammy.com/spooning pickup your own the 20 or you go to branch shop similar shop I challenge everyone to this challenging storm to shop and commit to go into some flower shop to go about trying to forgo to let my tummy.com/spoony is exactly right discount we got a little low show special get you can also like and share the program the podcast got check project.com and you can also find us at YouTube search get to project and you can go to the page and liking look it does look at Dr. Brown in the video you can even see that Brian showed up and much nicer clothes and waited for a coat restart episode wanted tuxedos and we've just gone downhill that's where your body right now – we got a costume shop three warrants and they came in just as a hot dog one time to find the episode that is now it is elegiac well I'm quite sure I hate to break this to we did a whole show and silicide and that he thought he was dressed as a hotdog the whole time flow show I was like you. It's it's about suicide yeah oh yeah I didn't know know know know like I could hear sound like and I could that could you not get I wait to hear Seneca to sound even when I'm still there which is which before we get into a lot of questions I have for you about how your journey with this and some Photoshop and how you help your community you know there's there's a lot of stuff there's a really good chance that psilocybin will be either a therapeutic drug or even over-the-counter product and not too long really things early oh there's some really cool research coming out mainly on depression opioids that comes thing for his part for your project we should hook him up with the Dennis even he would mean the applicable science from Hector Institute would be interesting I think in the chemical what was cool about you is that you're also a grocery store teacher so you do a whole show on sulci than the go does this habit you like jet Philip taken the lens billet portobello have a behind-the-scenes GMO products yet what we had we had a mushroom expert on cold Cooper read and he was describing how you can grab the and he was using the different terms of the mushroom and you can tell the silicide and content based on how it turns purple fastening really that is fascinating that I'm so into mushrooms right now not just the trippy mushrooms but how complex have been massive of a kingdom this is it so interesting he forages for mushrooms and he can say which ones are edible which ones are also all the so they don't become an oncologist or at least one professional trading the mycology acumen of exec with a yellow you're barely what he's referring to Dennis McKenna's a few years ago where pale you effectively showed up with microphones and just put them up in the air B&B that we are at just happen to be that the Godfather of psilocybin mushrooms who is a PhD in mycology really the him and his brother wrote a book on how to grow magic mushrooms when they were in college and it's like the Bible still so he hung out with us for like two hours we just did just geek out on mushrooms and fastening the therapeutic side of it that O'Brien was what is what really got my attention and before he came on to tell us even some of the cool stuff was just the data they had some hindrance to the blaze and is in Idaho and they had people smoking cessation for instance one but six months and 91% success rate what was even more astounding was it five years it's well over 60% smoking cessation 60% got really sick 64 – 16 change massive like that is massive like when we talk about the what's the drug that people take to get off that 00 Chantix Chantix that's like 35% at six months really that's what their standard is right now and this is studies are coming well that's the study of the half-truth Institute new studies are coming out of Johns Hopkins looking in the getting very similar results while it's just it just shows that there's a lot of things that we have left uncovered that's for sure and mother nature that probably could help with disease states and their doing the research on the witches are super exciting that it's very exciting survive for you to get where we are at some flower shop today you let us know you were born in Oklahoma they did what town and not a true okay those are unders six months I think you go to because by six so I can still consider myself to be a Texan guy yeah Dr. Tinker Air Force Base my guy was in the Air Force at the time house I was born there in Oklahoma think is $4.36 is what I cost him so to achieve better cost them a lot more later on their dad to remove the text structure that and gosh my background you want to know RB I got the military back in the know 89 to 93 is when I served as holes in the purse go for French Army nice Army yard mighty preservice appreciated the what got me interested I guess really in health of my first duty station was actually military intelligence duty station knew that from 89 to 93 9380 993 so a friend of Rich Hagedorn patriot leaders liquor with eight anyway they started a veterans organizations that are doing pure whiskey vodka held as we have heard okay I were just about hundred first airborne at that exact same time that really is I was and I was in college he was the was doing that one yeah well yeah you do the exact same thing that you did he was paratrooper that's awesome and I was a paratrooper I dumped more radio operator but I got to be stationed in the military told units not love the detective work oh I was there me all the information coming in trying to sorted and disseminate that to the higher command so forth that's what got me interested in going a I wouldn't mind being in the FBI one day guess what I really wanted to educate I think I've always want to be in law enforcement we are not but my second duty station was a medical and so actually when we went to the Gulf War I was in a medical unit we sort of picked up no bodies and things as we went through the way and love the medical side and soft like me don't want to do this so I set soon as I get the military I went through EMT school I went to the police academy and that's I was just driving that way to really be BBB FBI agent one day is my ultimate goal and then that God had other plans for me I guess in the your 9093 my dad was building the store in Colleyville and need some help putting up shelves and so what wells waiting to get on the four Police Department I went over there to help them out and I met my now wife at that point time to and so I had to make a decision on do I want to pursue the law enforcement career or stay with the store in that I actually stayed with the store and the way I look at though is that what drove me in the military of the military intelligence in the medical side it really shake need to become what I now call myself the body detective in the sense of saying instead of trying to catch criminals and investigate the criminal side investigating the body and that's where I turned that attention focused to so I'm in nerdy but hard to as well too I met you I guess you're the bigger nerd I get out I thought I was a pretty big nerd but other data

united states america god tv jesus christ american university netflix texas canada health israel europe google china bible internet los angeles coach olympic games americans germany west phd colorado building dj joe biden european australian toronto ny european union healthy dna holy army nashville iphone institute east argentina kentucky fbi authority cnn journal iowa oklahoma md oprah winfrey wall street south carolina sony cbs valley harris southern california wall street journal navy reddit psalms democrats starbucks mississippi midwest senate cd commerce michael jackson nebraska west coast cbd norway idaho air force oz denmark san antonio democratic fda rogers ebay independence day godfather mark zuckerberg bronx ganz heritage parkinson mormon chamber creek norwegian costco us army att reno gulf nasdaq fort worth texas blanco texan soto imperial photoshop bradford town hall gmo helsinki cvs hindi laden kpmg cbt nih cb sears viagra emt walgreens argentine johns hopkins doritos mps csi michael j fox gulf coast sunflowers gw dow lays roundup seneca oakland raiders pta shabbat dsm browning camacho bedford osama cabral gulf war uc irvine comand alicante indo kalamazoo primus endo jim gaffigan lou gehrig nsf ecc frito lay kobayashi nido c5 benders impala gcp cvd shoppe ibf ppl ecs icbm tarrant dryden kunkel sills mengele teleprompter breck autocad asada metroplex delisle negron tarrant county cosco texas city ankeny bcb dennis mckenna litton french army bill davis sebo ietf linus pauling ifn bluebonnets kim brown grell coas cd1 melanie avalon amsoil toradol united states china dowson atrantil tinker air force base ankeny iowa

Travis Page, Pharma Rep & Team Roper

gut health sibo kenneth brown atrantil

Play Episode Listen Later Jul 25, 2019 117:16

Travis is a former collegiate team roper and bronco rider, that has found a career in relationship building and sales.Incredible science review about polyphenols vs aspirinTravis' experience and hobby with raising cattleTeam ropingThe conundrum of pharmaceutical representation vs fairness and the lawSERIOUSLY FUNNY examples of medical sales experiences, from erection pills, to pain relief side effects, to unexpected results from an experimental weight loss drug... You will love it!Nancy husband and wife may kiss the bride connectivity care whenever you need video chatting with the doctor right from your phone so I don't need stitches thank you Dr. United healthcare health plan benefits may vary helps if I need to make their morning live show I was on so that out of the mud you Mary and for Larry where is Jeff when you need him for this is the gotcha project episode number 18 I McGregor with your host Dr. Ken Brown what's happening what's going on up so the writing were already up to this is fantastic were having some great responses I'm even like bumping into people that are looking us up that's a good show gut check project canalboat we are 18 why not 18 years not quite there love my tummy.com just who had knocked it out the bag lobectomy.com/spoony check that out if you would like to get your own Arbitron teal the reason why moving so quickly today is because we've got some studies to get to we've got an incredible gas from an industry that we don't always get to represent on the show that in a course is going to be Travis page 3 of Travis page on he is a drug rep but is also very interesting upward to talk about a lot of different topics but were not to talk specifics of anything know it is to be a general just Pharma thing when I can get him in trouble now is generic company will not be brought up is generic drug won't it's going to be really neutral so there you go Travis yeah Travis will will not reveal his company and I even asked him if I can rhyme it with other words said no idle whiteboard all the guts to hold it up withhe said it won't won't happen so that's about what is a lot of stuff but one of things I do want to talk about is the stories that you had being a grubber the stories that I've had through the years in training what's going on how the drug industry is changed in like this the regulations that have been placed so it's a wild thing because I didn't realize as a young person going to the doctor with my parents what why in our small town to Gainesville occasionally was somebody in a three-piece suit sitting amongst all of the people in the in the waiting room and they always seem to be holding pamphlets and couldn't wait to get in and they didn't have to have their name on the list and they would go back but a lot of things has changed since those days and the way that pharmaceutical representatives have to become educated how they represent to the physicians how they support the positions with their staff and patients etc. so there's so want to get into in a coursers lots of others lots of funny stories to go along with having a yeah a pharmaceutical rep but yes the big news in the big news happens to be in conjunction with the KPD health box and before we forget I wanted you to touch on the feedback that you got this last week and then what you have coming out is a little there's actually an updated change so we did the box opening last week with the KB of the health box but this is a really exciting thing this is a brand-new venture for us and for member box and they did an amazing job and I've had some great feedback my patients were to make big differences you met him boxing is a primary got box yesterday we sat was Sarah Jean and were building next month's box and were making it even better because more vendors are allowing their products to be part of member box you can build your own box once you get going this is really exciting I want to personally change the healthcare landscape naturally and allow people to really start changing things about themselves this pretty awesome because some of the feedback that we got from our patient just yesterday it was scope to received her first box and she said this is amazing I don't have to guess anymore and I thought that was really awesome to have yet another new element of a patient testimony it says this is helping me be healthier and saving money, the biggest thing about the boxes once you realize that there is that study that came out the chilled 79% of the stuff that you're buying at big-box stores or the Walgreens GNC late that article came out which showed that it did not have on the label what was arching the capsules so we took the liberty of going okay you look@thingslikeexamine.com consumer labs and you make sure that things are third-party tested then you realize okay what studies have been done that have actually shown O for instance tumor does do this or trunk teal can help in different ways we get the science to back it and we vetted the products and you're able to get it a huge discount so this particular box hundred $47 for some people that's that's out of range but a lot of people are spending to 5300 on supplements and you may just be throwing it away so hundred 47 to over $250 worth of vetted supplements one of the really exciting things is one of my patients her husband passed away of Alzheimer's disease right and she he was an artist and so she took his original art and she's made cards for basically blank cards thank you cards old-school member like instead of just texting somebody hey thanks that was awesome to catch you write thank you for doing whatever will on the back of it all the proceeds go to the Alzheimer's foundation so were you put that in anybody's box so our office purchased all of her cards and were to put that in the box and I just want it's an opportunity to Cordish to share that message others diseases like Alzheimer's which are really devastating and people you will be reminded of it Mrs. original art that's being sent to restart interact on hey we can put this in your box like that's awesome thank you that is awesome and if you've ever wanted to go and use a physician's recommendation as you move through the aisles of where what supplements actually work which brands are the ones that I can trust and which ones can I save money on to accomplish all of the things that I want to to supplement mount health that's what the K BMD boxes all bouts of KB MD box.com will direct you to where you can learn more to see a video of Dr. Brown on boxing the first months box that'll be replaced here pretty soon when we basically updated and unpack month number two which was very similar to one that always has small little tweaks just to basically improve your health and you can join and you can pause at any time there was never go to the you can go to the the member store and build more build you can deftly build more he can remember boxes getting more and more products in their really and it's all you know I want do is build a box it's based on science speaking of one of our people has member box set me article this morning that I normally would really go to personal stuff here but remember you can little love my Tommy.com/spoony and get a big discount and outrun till you're wondering okay will I don't have bloating or anything like that this article was just sent to me about 15 minutes ago in the article is anthocyanins protect the gastrointestinal tract from a high fat diet -induced alterations blot within burial integrity disposal really fancy these are the molecules are talking about right anthocyanins and what they do they looked at mice and they fed them a typical high sugar high fat American diet and they demonstrated that when they did this that the mice became fat they had insulin resistance they developed steatosis which is fat in the liver and they showed despite Elsa so the bacteria got screwed up and we got then they gave the mice the same molecules that we have and are trying to fed him the same diet and it started to reverse all that process so the science is coming out on this is so fascinating so if you don't if you're not taken Toronto right now because you do not bloated you might want to do it if you're eating a typical American diet leased from the small animal studies so that's and that's in the box and that's one of the main ingredients that's only one more facet in terms of what are 20 or just straight polyp I tried to learn not it's really what polyphenols can do to enhance or protect you and your health so now we know that it works well for gut now we know that tab with that Dr. Bo tells research from the UK from Exeter that polyphenols daily for athletes actually improves performance and tissue perfusion from from blood flow in a course you slow down your recovery time all of that comes from polyphenols not to mention making your endogenous or your your normal CBD your your normal cannabidiol that you have in your body work more efficiently there's just benefits to having polyphenols in your daily diet so we built this box is a gut health box right when you start looking for science to get the polyphenols for performance you get the megastore to increase the diversity of your bacteria so that they can actually use the food that you're bringing in and then the little thing we talked about before was true see that's the micronized hydrogen to improve your VO2 max meaning that you can actually have better oxygenation these are all studies that have just recently come out and of course you get a big steep discount on KB MD CBD oil service it's exclusive to everybody he's a KPMG box number no doubt that will almost all of my patients are on our Toronto plus KB MD CBD because the molecules are trying to augment your own endogenous and or cannabinoids or in other words your own CBD that your body produces and of course taking CBD is like a insurance policy against the world because it's really get you back to balance with your immune system and your nervous system speaking to CVD so I've tweaked my back in the past several years ago a few years ago and unfortunately just this last weekend Gage was out playing basketball up in Kansas and I went to watching and I decided to go engage in a workout and I lifted incorrectly I knew better it's a it's a it's a routine I work at that I normally do but you saw this was Ronnie Coleman 600 pounds on scrub I did 550 550 is from take it easy just be safe though truthfully it wasn't that much weight but what I did I put myself in a in a compromising angle that I don't normally do is in the equipment that usually use I knew better but regardless I did get a small spasm in my lower back usually the past it would take five sometimes seven days to really get more mobility that that injury gets it's a small injury occurred Sunday and you saw me pushing beds yesterday up at the end of center and I'm not 100% but the only difference that I have now that I didn't have the last time I hurt my back from lift is it I take on trying till daily antic CBD now and I think the level of inflammation that I experienced is less now it's anecdotal it's just me I feel great today will Susan feel totally 100% let's go back to that same doing the exact same exercise injure yourself but don't take either that way we have a control group and we have a treatment group you took the words right out of my mouth is exactly what I want to do is drive back to Wichita Kansas Wichita are our lovely and nice has nothing to do that it's just five hours from here to get there so at say it's a long round trip looks like your haircut I did get a haircut and yeah several of them cut several of them I'm such a fancy place what you talking to the person that was chop in your hair I was the hairstylist that's it you you call a woman the catcher here I guess that the hairstylist was cutting my hair and she asked me use it kind of funny in the chair and I say well actually just kinda stretch my back go back I tweaked it but I'm getting better and then she went on to tell me a story about she had been rear-ended by a large truck that erection Torcon on Interstate 35 in Denton and it took about eight months to get back to where she could hold her arms up to cut hair and then you know work at home in the scissors and without feeling fatigued lots of pain so I stress it would all work that she said well I did a few things that the pain doc recommended that do it it stretches but what made the biggest difference for me is when I found a CBD that I could trust and I could take but the hardest part should try several she has rides whatever we value this all the time she said the hardest part was finding one that was reputable that she could depend on didn't break her wallet so the one that worked the best was running her a little over $135 a month and she said it'd always make it to the end of the month even though she was following the instructions on their I let her talk and it was almost like she just walked straight into what you know what it is that you do it sought his ashes what would it have made a difference if you had a physician it said I recommend this CBD because it works clinically for my patients and here's why and she said I would've done in a heartbeat if so what if I could told it would have been about half the cost of the hundred and $35 brain that you are using she said well obviously I would've saved money I would've felt better Chuck told her that KB MD she she went straight to an ordered some so it's it's it's really kind of cool that we remove the access of the cost and that of the worry of is this legitimate CBD and so there was talk about it notes the waters are being really muddied right now. His boots of there's people there's essential oil companies that outrun at CBD there's every try to put it in different things and people ordered off Amazon which right now you're getting hemp seed oil united in getting CBD right is lots of mislabeling and so I think it's really important to have something to trust same thing that you're doing and buy a supplement or make sure that your CBD use is of quality something will happen is also on the topic of that of yesterday I I like it is so Greek salad and turkey patties from from Kenny's burger which is right by my brother my office to tasty Kenny's burgers but Chef Eric said that he was with him on the show under someone holding to it here pretty soon but I was I was Artie talking some people some somewhat regulars there was I googled you and I found you show LOL my guess it's also active on the show because it googled me as a doctor but find it a joke of growth nature and that she was tell me more about the CBD and then just immediately started this whole discussion about passivity was her talk about it and then it went sideways because she goes what you talk about tomorrow Mike that's a great thing am open to looking at different articles a look at what is really interesting one that just came out about a fecal microbial transplant is not effective in irritable bowel I forget that I'm at a restaurant you said that getting said yeah out loud to your class he got real classy records. The never disconsolate that I had to explain the article on the Gladwell will so you take what you slurry it up and put it I'm sorry document can you please leave the stage and a restaurant as I know I was like what yeah okay I'm just as it doesn't get any better not go into detail about how they actually did it which is what I want to do later maybe go to a restaurant that is not does not sell more burgers is Chevron Arcana came out was like yeah let's just move you back in the corner over there and let everybody else eat the burgers no need to wash your hand yes exactly so that we talked about CBD they found us just by doing and then I got put in the corner because I have a potty mouth it's okay well yeah is about a subject hey I just a real real quick reminder for all of our listeners be sure to like and share the gut check project and then shoot us an email gadget project.com under a connector contact let us know that you like and shared we got hundreds of people over the last few weeks so we are still going to give away the signature protection package which is a combination of Tron deal and KPD CBD month supply direct from yours truly Dr. Brown so where are we on the research topic for this week Jess of Unitech before Travis Or Did You Want to Save It's for Now Save It for a Little Bit I Want to Get More into Tell Me What Happened with the Family That's Compacted in Which Delegates You Go That's Great Is His Last Big Tournament As a Yeah Is a Highschooler before He Starts Haskell Ball I Got Have One More Turn up the Rest of the Summer but They Went to What They Call a Great American Shootout It It's Basically Huge Huge Basketball for Kids Who Are in High School to College Coaches Come in and They Watching He Dent the Weekend before down in South Dallas Duncanville and Other Match of Seven in Kansas Were Were Great I Mean They They Were Challenged They Ended up Finishing Two into One Teenage Face Twice They Beat Once in the Last Two Later and but If It Was It's so Good for the Development of This Program for Them to Have That Kind of That Kind of a Set up and It's It Puts Them into a Real Game Environment and That the Boys Worked Hard so It Was A Lot Of Fun and It's Always Good to Get at Town with Any Family Member Where You're Kind of Forced to Sit the Car Talk, but As Funny Subjects Laugh So It's Now I'm Not Really Fortunate Both My Kids Did Have Good Road Trips Exactly in and You Guys Are Sit There Talking You Know He's on His Phone Now Which Due To the Lot Where They Put the IPad the Back Everything Else We Do the Same at like Whatever We Do Road Trips It's You Realize You Hate to Drive Yes but I Have Kinda Grown a Little More Fond of It Because You Gets up and Talk Yeah My Undivided Attention When My Back Was Hurt Then on the Way Back so Gage Gauges Forced to Drive and I Could Even Look down to Look at My Phone) That We Had a Great Trip and Then Abreaction Stayed in Town Because Our Youngest Son Here the Best Will Tournament but Here's the Crazy Thing You Know That I Live in a Small Town or to Such a Small Town of 5000 People Marie Was a Part of This New Concert Series It Happens Indicator That They Would Just Now Starting to Implement and They Had a Large Music Acts That Amos Tony Leroux Who Came to Downtown Decatur Will Have 5000 and Change That Claims They Live in Decatur Property Had over 6000 People on the Square Just to Watch This One… That's so ALSO They Did a Great Job of Promoting and Bring Your Buddy Downtown so It's It's like A Lot Of of Americana in Canada Trying to Revitalize the Old Square and to Bring the Community Together so They Did a Great Job of Bullets People Downtown That's Awesome That's Very Sweet so That You and the Kids Well Okay so Last Week Show so the Both Kids Were Playing in Florida for Clay's For Clay-Court National Site and so Carla Had Just like I Think the Data Redoing the Show She Just Lost It before so She Was out Luke Is Actually Doing Real Real Good He Got Six Place 256 of the Best National Tennis Players in the Country and He Was the Youngest Which Is No Problem and What Was Really Cool Is That Carla Was There the Whole Time but She's Good Enough Now That She Can Warm Lucas up so She Was Lucas's Warm Apartment Nice so Yeah so I Thought That Was Really Really Cool so Last Night so They Came in on Sunday and Last Night They Start Asked Me about the Show Which I Think Is Really Fun so Carl Goes You Know What You Say about Me Tomorrow You Might Hello Point I Would Have Been with You Which Is like I Won't Look Us up so I'm like Okay Then Something I Could Not Do Liberals Don't Ask Me to Do No No No It's Impossible Bulges Flyby and Then Lucas Others Pretty Cool Because the Last Week You're Talking about How the Weeds Grow Everywhere Yeah and He Goes I Found a YouTube Channel Called Great Big Story Just Random Stuff Is Really Well Done 4 Million Subscribers Whatever Okay There Was a Story on That He Said Talk about This So Interesting and Will Get Only Gets up Patrick's Take on a Couple of These Things but It Is a Harvard Law Professor Who Dropped out or Just Quit after Practicing Law Just Said Turned on with This Became Forager So to Speak She Became a Weed Expert Okay And She Just Goes around Collects Weeds and She Takes Them to the Finest Michelin Star Rated Restaurants in New York City Where the Chefs Do Amazing Things with Weeds and Never Last Week Were Taught about the Fact That These Weeds Grow They They Have More Seeds That Grow Were in Inhospitable Environments They Have All These Different Sure Were Probably Looking at A Lot Of Food That We Could Be Dabbling in but I'm Not Encouraging Everybody Run out and Start Eating Everything in Your Yard EE I Remember That Reverent Story Ever into the Wild Right the Alexander Supertramp Who Happen to Eat Something and He Was Bare Garlic Instead of Wild Garlic Which Was Listed on the Same Page the Buckingham Dying in a School Bus in the Wilderness of Alaska but Yes That Moving the Book Is Really Great Actually Acts and Injuring Them in a Book on My Think at the Book and the Action Was an Article in Outdoor Magazine and Then It Was Became a Book and I Became in the Movie but down What Was That We Need That You Said That You Are You Ready Okay so Yeah There so Many Edible Plants but Having A Lot Of Them Require Special Preparation There's One in Texas Called Pulte Salad And down like a Silver Dollar Weed The Problem Is Yes the Boiler like Five Times Boiler Drain It Boiler Drain and Boiler Drain It before It Doesn't Make You Sick and Ends up Just Being Another Boiled Green but My Question Is Always Point How Many Children Did You Make Sick Throat Got up I Will March Me Know Jill's Sixth Mother Let's Try To Boil More Time Drain It in and Try Again I Never like Blowfish How Many Sailors on One Ship Died. I Cut It Correctly Yeah but Having Kids Is Probably Act of Desperation Is to Find out What You Mean at Some Point You're Kind of Force You Do Yeah I Mean and Forging Is a Big Thing Now I've Been Assuring You While the Hunting Wild Mushrooms in I Know He's Actually It's It's Awesome but It's Really Scary Because I Don't Know You Know We Have from Even It Comes to Mushrooms On One of the Episodes We Had Cooper Read on the Atkins We Did a Whole Episode on How to Identify Mushrooms How They Grow Idea That's Fascinating to Me That My College Is Coming I Don't Know How in the World They Can Get That Confident I Can Think You Could Study and Study and Study but Then Suddenly You're out on Your Own Going and That Was Pretty Good Really Want You Try That Make Sure It's Pretty Good Note School Is out Is Morels Have Not There Is No Other Mushroom That Looks like Them That's Poisonous so You Want Hot Mushrooms Be Sure to Learn How to Identify Morel Mushroom and Forget the Rest And 80 Bucks a Pound It's Been Shopping for Where Do You Find Morel Mushrooms and Well All over the Place at Texas Not so Much North Texas Maybe Far North Texas Arkansas Missouri Digits Did You Know That A Lot Of Texas Mushrooms Joke in the Arm of the Supercollider There Are Going to Build Oh Yeah so That the Tunnels They Began to Build Around Here in North Texas That Quercetin Completed but There Are These Gigantic Tunnels They Had to Make That They Made Use of Them And Eight They Cultivate and Grow Tons of the Mushrooms That You Get in Your Grocery Stores in the Old You're Kidding Supercollider Tunnels Yes It's Really Awesome They Have Is Awesome That My Ankle Time I Know That Jerry and Ray They Walk in a Manner like These Big Wheels and I Mean It's like the Perfect Tank No Sunlight Environment for White Mesh Row Ever since Ever since That Episode I Become so Intrigued by Mushrooms Was Even a Netflix Special That I Watched about Mushrooms and How Prolific They Are All the Things That You Do You Know Him As You Know I'm a Big Fan of All the Research Going on with Silicide and the Micronutrients and in Mushrooms Are Me and Can't Get Them Framed from Any Other Sources It Is Amazing with a Half-Hour I'm Looking at the Time I Feel This Is Unbelievable and We Yeah This Is Unbelieving Okay so Coming up Next Generic Travis From the Generic Page Family Talking Here Outline a Cyclical Generics Is Generous Is There's There's There's It's Also Generic It's a Way to Teach You How to Be so Generic That You Will Be Invisible Will Generically Laugh Your Ass off If You Are Trying to Quit Drinking or Doing Too Many Drugs Listen to Me You Don't Know Me and Will Never Meet I Had a Problem like You Want I Drank and Used a Party a Little Too Much till He Got Out Of Control and Almost Ruined My Life I Realize I Needed Help to Fix My Problem before It Totally Destroyed Me If You Tried to Fix Your Drinking and Drug Problem and You Know You Can't Do It Alone You Need to Call the National Treatment Advisors That Will Immerse You into a 30 Day Program to Replace Your Old Habits with New Habits and Totally Change Your Life and If You Have PPL Private Health Insurance the Entire Program May Be Covered Fix Your Problem Right Now before It Gets Any Worse Get Clean Call Now and Learn More 800-296-1252 800-296-1252 800-296-1252 800-296-1252 Are You Tired of High Cable TV Rates Sign up for Dish Today and Get a $500 Bonus Offer While Supplies Last Loss Locking Your Price for Two Years Guaranteed Call American – Your Dish Authorized Retailer Now 800-570-6630 800-570-6630 – 800-570-6630 Authors Required for the Occasion 20 from Early Termination Fee at the Auto Vein Restrictions Apply Call for Details Fast-Track Student Loans Can Get Your Student Loans Out Of the Vault Stop Any Wage Garnishments Stop Collection Calls and Stop Seizure of Your Tax Refund Give Yourself a Break to Stop the Stress and Get Your Student Loan Payments down to As Little As $25 a Month Based on What You Can Afford to Pay 800-709-4395 800 709-439-5800 709-439-5800 70943950 Projects We Are Now Joined with Mr. Travis PageIs the Generic Pharmaceutical Everything That Was Brought on Correct That's Correct Okay Now We've Just Gotten Legal Permission to Show His Face That Is Not That Generic Is That Some Other Cool Stuff Going on That's How You and I Originally Met You Had These Studies Cattle They Were Doing Anything That That There Were Supposed to Tell Me to Bring the Girls Alert the Cold Court Entered an Elected Mexican Cattle Espanola Yeah I Went to His Ranch in the Rye Had Little I Little Discussion Was like Him He Stood Back to His House yet Is How We Got in Line Had Never Thought about Speaking Spanish I Don't Speak Spanish but the Mexican Guy Needed You to Come over and Help Me out with That Once We Got in Line I Was like Hey I Got a Great Idea I Hope You Want You Come to My Office and Bring Lunch Occasionally That That's How It Works Yeah That's Right. That's Really All There Is It's Almost 90s What Is What You Say 97% of Pharmaceutical Reps Started in the Cattle Industry Oh That Is It's Much Lower Than That I Hope My Way off Bad Stats in Math and so Well We Get Now That We Have Somebody from the from the Farms of the Industry We Wanted to Have Travis Calloway in on Some of the Articles That Were Going to Discuss Today and in the Science Corner From Dr. Brown so Let's so I Got It Norma What Transmittal Do Sometimes I'll Take a Really Kind of a Cutting-Edge Article and Take a Deep Dive but There's Several Different Studies That Pertain to Our Previous Shows I Just Want to Come to Gloss over Them Wanted to Let Travis Decide Which One Were to Talk about First So Very Important You May Just Pick One of Those Pages Are All Negative That Gary Sakata Description First Actually Do You Want to Hear about the Tie between the Jott Micro Biome In a Potential Way to Help People with ALS Pamela Tropic Lateral Sclerosis Is Usually Known As Lou Gehrig's Disease Stress Data Was Choice Number One Choice Number Two Would You like to Hear the Previously Discussed Kenny's Restaurant Poop Transplant Story Choice Number Two Choice Number Two or Choice Number Three Out Of a Canadian University They Been Able to Identify And Produce Molecules in This Behalf Plant That Are Actually 30 Times Stronger Than Aspirin For Anti-Inflammatory Now You Heard Eric Talk about His Back Could Be That CBD Was Doing Something Real Nice We May Have the Molecules Three so This This Is Actually More of a Personality Test For You to See Where You Actually Landed Where Where You Headlined Is Generic Travis Your Job Is on the Line Yeah I I Feel like It's a Personality Test the Number Two with the Poop Would Be like to Go to Choice One with the Got Biome ALS Biome LSO Study Just Cannot Hear with I Looked at the Motor Neuron Disease ALS What They Have Found Is That There Is a Clue That This Horrible Condition and We Had Brandon Brown on Last Week We Were His Dad Died We Went into A Lot Of Detail about the Just Slow Progression of It and You Know We've Had Other People Call in That Event Actually Dealt with Us so Is This What Killed Stephen Hawking They Have Linked Changes in the Micro Biome That Live in Our Gut so They Have Discovered That Micro Biome Will Secrete a Proper Micro Bar Will Secrete Nicotinamide Vitamin B3 And This Appears to Slow the Course of Motor Neuron Disease by Improving the Function of the Muscle Control Neurons in the Brain Now This Is Pretty Exciting Because This Is the First Time They've Been Able to Show How the Micro Biome Will Produce a Neuroprotective Molecule and What They Showed Is That They Took Some Mice and Dooming a Biotics in the No Longer Produce So When We Start Destroying and Dropping Bombs and Not Feeding Our Microbiota We Don't Produces so It Nicotinamide You Made This May Seem Familiar to You Because We Were Working with the Guys That Produce Nicotinamide Ribonucleic Acid Which Is a Precursor of This so Basically What Happens Is Nicotinamide Gets Converted to Something Called NAD Plus and This Converts Food and Energy It Repairs DNA and It Helps the Circadian Rhythm so All These Things Eventually I Want to Try Get Some NAD in Our Box Sure but so It's Pretty Exciting Because Once Again It Comes Back to the Gut Can Affect Your Brain Were All about the Got Right Axis Here And so That Was Kind of Exciting and We Should All Think before We Just Go over to Gazette about Taking Antibiotics to Eat This Crappy Food Because Your Kinda Doing Some Neural Protection Every Time You Eat Polyphenols Every Time You Improve the Diversity of Your Micro Bio/ME I Think That You Could Look at There's Two Inputs to Your Brain and and Its Health One Is the Obvious It's What You're Doing to Learn and Keep Your Your Mind Active but the Other Thing Is Just Plain and Simple You Rest of Your Body Has To Get Nutrition From Somewhere in the Only Way to Get It Eat What You Eat in a Matter I Would Just Shown Time and Time Again That the Typical Western American Preservative Filled the Diet the Preprocessed Food It's Just Destroy Your Health It Really Is We Were Seeing an Epidemic of Autoimmune Disease and Everything Else Which Is Why I Think Everyone Has an Endo Cannabinoid Deficiency We Always Talk about This There Is the Gastro Vessel System the Cardiovascular System Neurologic System Will Have an Endo Cannabinoid System I Want to Be the First Board-Certified Endo- Kanab and All Just out There I Think I Can Because I'll Have To Form the Whole John Ronald to Certify Myself Immediately to Me Interesting Residency for Sure It Will Be Really Interesting Yeah So That the Other Study Were to Talk about Which Is These Guys Figured out These Two Molecules Cannot Live in a Can of Light and Be What's Interesting to Me about This Is That They Are Flavonoids So in a Full-Spectrum Hemp These Are the Polyphenols Which Are Also Was CBD Original CBD Nobody Talk about All the Other Molecules That Come along with It We Talk about the Terpenes Which Are the Essential Oils and We Talk about the Flavonoids Which Are the Polyphenols Right And What They Showed Is These Template and a and B They Provide the Anti-Inflammatory Benefit of Taking a Full Spectrum Interesting and They Showed They Can Show This Is What's The More Interesting They Implied That They Show That These Different Molecules Are 30 Times More Effective Than Taking Aspirin by Blocking Prostaglandins Prostaglandins As Part of the Arachidonic Acid Pathway Okay yet so Just for Those Who May Not Be Completely Aware of Their Economic Acid Pathway You Start with the Prostaglandin and It Moves down I Think It's Either Level I or Level II You Get into the Cyclooxygenase of the Cox Enzyme Correct Correct and That's Where Aspirin and Those Other NSAIDs Would Work so Basically You're Saying That a Natural Flavonoid Will Stop or Prevent That That Progression down That Pathway Earlier Correct Exactly This Is Patrick He Is Just Studio Touching Things Very Range of ZZZ's Adjusting Camera Started out There So So What's Really Actually about This Is That There's No There's Big Business I Mean Back When I Was a Resident There Was Talk of a Farmer Here for Second the People Throwing the Money Out Of Us Were the Cox Two Inhibitors Sure of Who I Can't Member Who They Were but They Got There Pulled off to the Realtor Causing Heart Attacks Afflicted by Vioxx Was One of the so Just to Finish up This Article There Was Really Interesting Because I Was like Wow This Is so Cool and Then I Went These Guys Didn't Discover This in Fact It Was Discovered in 1985 That These Molecules Did This What They Did Is They Discovered the Enzyme to Produce It So They Want to Start Manufacturing Just These Two Molecules And They Probably Will Make It a Drug Sure like They Want to Do so This Is Interesting Because We Talk All the Time That the Full Spectrum Allow Mother Nature to Do Her Thing So No Offense of the Farm Industry but Frequently Though Find Something Oh There Is the Molecule during This Then They'll Manufacture It and Hope That It Works As Well As in Mother Nature but We See It Time and Time Again That It Doesn't You Need Everything in the to Do It and I Did Have Some Fun with This Because I Want on Reddit and Looked at Somebody I Recently Discovered Read about Three Months Ago Yes It Just Started Ready Friend and I'm like Reddit Thing Is Super Cool When You Find That Modems Had a Quick Side Note They Go on I Gonna Read It Funny Pretty Good Way to Start Your Day Just Looked at Cop Arresting a High a Really High Kid and I Don't Know What Happened before Goes the Cop Looks at Him and Just Goes I Mean like When They Make Fun of High People and They Portrayed in Movies You're Mad As Hell Man Thanked Its Front Page Read It for Sure It Was so Somebody Wrote Them Basically What They're Talking about Is That It's Been Known for a Long Time That These Kenna Flavin's a and B Have Been Able to Do This and the Study They Were Referring to His 1985 but It Just Kind of Implies That This Is You Know the Way Things Go What's Really Cool about It Is That There Are Potentially Thousands of Other Molecules We've Not Discovered In These Plants I Made Such a Complex Plant Which Is Why Think It Is so Many Things so That's Article Number Two Article Number Three Is I Get Asked All Time on My Patients about Fecal Transplants and so You Take Someone's Poop Stick and Somebody Else and A Lot Of My SEBO Patients A Lot about Your Mobile Patients Always Asked That Randomized Trial Came to the Conclusion That Now It's Not Any Better Than Placebo the Real Taking Someone Else's Poop Does Not Help Irritable Well Hey Just a Curiosity That Particular Study How Big Was It and Are You I Do Think the Methods Were an Effort to Be Disk and Totally Conclusive on That Element Now I'm Sure It's Not and I Don't Member Lussier Got off Public Results I'm Only Curious Because We've Seen in the past but Sometimes You Can Hundred and 75 People Recruited Okay 75 Now That Being Said It's like All Things for Me and Some Other People Would Go Ahead and Critique Us so They Took the Capsules the Frozen Food Pressure Okay Though Some Would Argue Is It You Know Is It Actually Working to Present to D Have To Go in and Do This so Do Remember Quick Side Note We A Few Years Ago We Were Interviewed We Had This Yale Gastroenterology Fellow We Took A Lot to Eat He Was Considering Joining Us and His Research Was on Fecal Microbial Transplant so Taking My so What They Would Do Is Take a Skinny Mouse and a Fat Mouse and They Would Swap and See What Happened with That Mousey Little Skinny Mouse and They Were Showing That Fat Mice Started to Lose Weight after Getting the Fecal Transplant Skinny Mice Gained Weight So While He's Telling Us This As You Can See I Have a Habit of Talk about Poop and Restaurants Yeah Our Waitress Was like What Hold on to Explain That He Goes into More Details I Guess I Will Publish This in It's Really Exciting She's like He Was Ever Thought about How Their Fat Families Is Genetics or Are They Sharing Their Poop Once You Live with Somebody Long Enough Whether You like It or Not You Sharon Poop and Just to Women with Somebody so She Just Goes Oh My God It Looks over the Water Boys like Six 420 S. West That Just Became the Sexiest Man in This Restaurant Yeah Yeah Yeah I Did So so Anyways Brigham Young University Just Came out with Actually Did a Fecal Microbial Transplant Study on Weight Loss The – Documents and so Is Small Study but It Actually Did Not Show That Improved Weight Loss I Had a Patient That Did a Microbial Transplant from Her Sister and She Ended up Getting The Same Diseases As Her Sister Though She Developed Acne and Hypothyroidism and Put on Weight It's Really Interesting Though Because I Think It Even United Whenever That Study First Came out from Brigham Young That Was That There Probably Are Still Some Environmental or Extrinsic Controls That There Probably Weren't Measured Because Did the Fecal Transplant Actually Have Number One Time to Change the Habits of the Desires the Person Had Now It Seems like There's A Lot Of Different Facets Whenever You're Talking about Essentially a Human in the Wild of the Western Civilization and And All of the Different Offerings That You Can Have for Food Sources Etc. Can Be Reversed So I Thought from a Generic Farming Nice Yeah so I'm in a Really Have To Not Beating in My Scene To Ingest Somebody Else's. Psalm Tanya Seems like There Would Be A Lot More Negative Than Positive to Write Well Will I Think That There's so Much Science Coming out on the Micro Biome We Don't Know What to Do with And There's A Lot Of People Who Are Really Desperate I Think You're on an Island I Think Most People Are Totally into Having Someone Else Do You Think That We Took a Poll I Don't Know It See This Is What He Brings up a Good Point Maybe My Sample Size Is Way Too Small Maybe I Need to Ask More People Than Just Myself Okay That Was No Pun Intended Right Your Sample Size I'm Glad Someone Is Picking up a Ladder Right after L Phoenix on Friday Obviously Travis Does Not Work for a Mixed Good Restaurant Is Awesome Yeah but No It's Believe It or Not It's a Topic of A Lot of Scientific Inquiry Right Now Yeah Microbial Transference the Microbiota What's Going on I Mean This Is People Not Ever since the Advent of the Phone I See More Pictures of People's Poop and I Don't Need to Just Keep It Right There Don't Know What You Can I Got the Good Imagination I Imagine That Is Interesting No and We Did Get Asked about That Quite a Bit at the Procedure Clinic About What You Know about Fecal Transplants but I Think There's Still Time Left to Discover If It's Well so It's the Brakes of Been Put on It Because Just Recently That Study, We Have People Died Two People Died from Getting a Fecal Transplant Because the There Was a Bacterium That Yeah That's What I Was in Salmon There's That Negative Outweighing the Positive Right Because There's so Much Negative from Its Waste Right I Will yet so Technically That's True but That's It Has Your Micro Biome and It Has A Lot Of Dead Things Is a Ton of Waste in It and You Know Poop Is Extremely Complex We Don't Really Quite Understand What to Do with It or How to Make It Better but We Do Know That Your Micro Biomes Your Genome within Your Genome We Need to Start Treating That Accordingly Give It What It Wants You Start Having A High Process with High Sugar Food You're Going to Have Bacteria That Are Going to Proliferate More I Will Start Sending Signals to Your Brain to Ask for More of That so Are You in Control Or Is Your Bacteria in Control of You That's the Interesting Thing Yeah Definitely Has Many Other No Words No That's That's We Just Waited Technically for Quick Studies Today NL Just Came out but Right Now I Got I Got I like Commit to One and Do a Deep Dive on It but We Were Able to Come to Cover the Cover Basis Rather While They Want to Gain It Well Travis Walking the Show Thank You Ashram so You Were Born in Carrollton Texas Correct Yes and Currently Now and of Course We All Teasing but We Can't Worried Asked Not to Totally Reveal Exactly What Farms It Was a Represent What Company That You with but That Won't Prevent Us from Talking about the Journey to Get to Where You Are Now so It Will… Let's Go Ahead and Cleverly Were Microfiber but the Reality Is Is That the Pharmaceutical Industry Has Been under Fire for the Last Decade or so Though Sure That the Regulations What Can Be Said What You Can Be Represented Have Really Been Ratcheted down in Some Part of the Fun I Want to Do Today's Talk about My Journey As the Doctor Where There Was No Limit Free-For-All It Was a Free-For-All to Now Would You like to Know You Can't Say Anything And I Can't Bring You Anything and We Can't Do Anything and Everything's under Tight Regulations It's Morphed A Lot I Mean Definitely over the Last Three Decades It's Probably Not a Recognizable Profession When It Was 30 Years Ago Compared to What Is Now Yesterday There's a Guy That That Worked with On the Primary Care Side That Will Just Call MAC Outright and He Was 60 Something Years Old He'd Been through He Made It through like Eight Different Layoffs over The Course of His Career Right Me Just Could Not Kill This Guy And He Was a Fixture Every Wednesday He's in This Particular Office Right and I Just Asking Him and Talking to Him about What The Industry Was like 30 Years Ago When I Came into It I Mean You I Missed out on On All of That Right and You Know It's It's the Only Sales Job Really That I Can Think of Where It's Not Okay to Take Your Customer to Dinner or Take Your Customer out for a Drink or out to Play Golf or or Whatever the Scenario Might Be I Mean Yeah One of My Best Friends Is His Family Owns a PVC Pipe Manufacturing Company Right They Live on That They Live on Entertaining Their Customers I Mean It's Expected Brian and I Is Not Funny Because Doctors Now Are so Scared Especially with Happen to Some Hospitals Doctrine Hospitals the Stuff That If You Own It If You Do Anything in Medicine I Do Not Want I Don't Take Any Money from You I Do Not Want to I Feel like a The High-Level College Recruit Just like Now What I Will Pay for My Own and Because He Is There so Much Fear on the Doctor and Roots like Look at You Being Influenced And the Reality Is There Was A Lot Of Money to Influence People's Behavior and That's What That's Why the Relations Came around His Right Is Wrong I Don't Know While Internet and That All of the Training and Everything You Get Is a Rat Now Is All Very Patient Focused Right It Is It Is All about Presenting a Case and Paying a Picture of a Particular Patient That Needs Help And That That's Really Our Job at This Point Is to Go Get in Front of the Physician Somebody Has the Capability to Improve Somebody's Life Right by Writing a Prescription or Doing a Procedure Whatever the Case May Be in Just Painting a Picture of the Patient That They See on a Daily Basis but Maybe Get Lost in the Shuffle Are That They Don't Recognize and Try to Paint a Picture of How That Patient Suffering and How You Can Help So I Mean I We Will See the Company Name but I've Been Doing Clinical Research for A Lot Of Different Pharmaceutical Companies and I Work A Lot Assigned to Place on Sears Has Some Really Smart PhD's That a Return to Work This out so There's There's All Different Kinds of Views of What This Industry Is and What It Was What It's Become And Everybody Insurance Companies Have a View of That the Patient Has a View of That the Doctor Has a View of It the Company and There's so Much So Many Moving Parts That Are Continually Moving so If a Drug Company of Or Research Division of the Drug Company Has a Pretty Good Product If It Doesn't Look like It's Gonna Be a Homerun There's Just a Recent Pharma Startup Were There Looking at Something in Cannabis in the Phase 3 Clinical Trial Was Looking Bad And Somehow It Got Leaked Their Stock Plummeted 81% On This The Rumor That the Trial Wasn't Going Well It's Crazy Because He Almost Are Stockholders in Industries like That You're Always Betting on the Future It's Never on the Present Value of What Merely Delivering a Good Service Would Heavy It May Have so Much Weighing on That in Fact If Armor the Number Correctly You May Be Able to Correct near It's Probably Grown since Then but the Late 90s We Were Told the Stat And That Was That so Much of the Money in the United States Of America Pharmaceutical Industry Is Strictly to Stave off the Costs of R&D and the Elements That Go into That to Move That Product Soaked over Told Is That before One RX Is Sold of Any Doesn't Matter All Comers Is Sold That over $1.4 Billion Had Been Invested Industrywide to Create Good Multifarious Trials the Experiments That the Development Of a Said Drug That Would Come with Every Lineage You You Yourself Even Said They Had That Started with a Steady Back in 85 and Now They're Trying to Find an Enzyme to Do Something Will Were 30 Years Removed from That so over That Time How Many People Spent Time Reading That Article so This Is an Aggregate of All of the Time and All the Research That Goes into This and Avenue Where We Can Improve Either an Outcome or What Have You Is Just A Lot Of Money on Top of That Before You Can Turn a Drug out to Somebody You Gotta Go through At Least Three Phase Clinical Trials and Then Moving to the Force Where the Consumer Will I Will Say This Travis Are Here Because Number One Your Atypical for a Drug Rep So How in the World like What Your Journey Man Were to Start College and Appear Yes so It It's It's Really Not That I Complicate Our Plan to Be Here A Lot Sooner Than That I Was a Mean on That Third Show Doesn't Start until I Was Right on Time for That Yes so You Are Talking about My Journey Right so I'm a Third-Generation Sales Guy When My Dad Went through School When He Came out It Was All about Computer Software and Hardware Right When I Was in School It Was All about the Pharmaceutical Industry and so It Was My Ambition Right to Be in Sales It's All I've Ever Done Don't Care If It's My High School Job My College Mates It's Always Been Involved in Sales so I Knew That's What I Was Going to Do in the Hot the Hot Job to Have Come You Know Back in 1999 Was Coming into the Pharmaceutical Industry and It All Went to a Small State University Which Was Mistake Right Great Experience Great Education but Just Not Allowed A Lot Of Alumni Support Board Job Right after You Get Out Of School You Know When and at That Point I Thought I Was Going to Be a I Thought It Was Going to Be a Pro Athlete Right Because We All Do When Were 18 or 19th And so When I Discovered That I Wasn't Going to Be Right I Try to Get into That the Job Market Will Sports So I I I Rodeo Road in College and You Know I Thought That That Was Going to Be Realizing Your Second College Rodeo Yes Scholarship Person That We Got on the Show the Odds That's Where I Show 18 We Had to Know Me That's the Elementary Him Percent Yeah Hendrickson Was a Rather One Robo That's Right Robo So What Would He Compete and What Was His Mostly Bad Ass Surrey Samurai Night Was That He Was a I Think He Was a Bronc Rider It Is a Professional Bronchitis Think He Was a Bronc Rider Yeah Yeah Yeah so That's What I Did but There It Was Very Evident That I Was Not Going to Be Professional at It by the Time I Arrived National Rodeo Person Liquid of the Skills and the Acyl Basically Your Your You're Willing to To Put Your Money Forward and Go on the Relative Absolute Zero Sensitivity in the Mail Nether Region There's That Your Behalf Shopping to Play Smudges As People Think That It Is That Often so We Don't Have To Worry about Being Somebody Runs up and Just Kiss You All of the Terry A Lot Of You A Lot Less People Sign up If That Were the Case Yeah No I Mean It's It's Really You Know It's It's It's One of the Few Sports in the World Where There's No Contract There's Nobody Paying You Unless You Went so You Gotta Be Able to Foot the Bill to Go Compete And Then Yard You Know Basically Sustaining Yourself with Whatever You Went so If You Don't Win It's Not Sustainable Is Basically What the Deal Is so That the First Job Interview I Had a College Was with Copenhagen's Goal Right Okay and so I Go down to the Office There in Louisville Used To Be on Main Street There in Louisville and I Go in There and I'm Talking I'm Talking to This Gentleman and It's a Sales Job and Ides Promotional Job and I Get to Go on the Road All These Rodeos and Stuff and Promote Copenhagen's Goal Might Man It Sounds Fantastic I Said so How You Guys Health Benefits Magazine That We Don't Have That We Pay like 70 Company I Mean Yeah Yeah Your Initial You Will Take Jobs Coming out You Have To Eat so Did You Have Any Issues Taking a Job That Actually Is Harmful To Society yet so in When You're 18 or 19 It Are More Associated with Cowboy Than I Did It Measure Harmful You Know and As You As You Grow up and Mature You Realize That That's Not a Great Thing You Know What I Mean but an 18 or 19 I Just Associated with Being Able to Be Look at How You Look at Look at the Advertising They Were Doing Then It Is Sex for for Your for Your Peers That's Sexy to Be Doing Copenhagen School Started to Happen When I Was 14 Years Old I'm 42 Today Today State Not Today Matt How Is Patrick and with Everything. I Wish It Was My As Long As the Mud Pie We Yeah so Know They Definitely Marketed on the Old You Your Walt Garrison Everything I Mean You To Be What You Had Done to Dip Snuff You Know At Least I Thought That When I Was You Know in Middle School You Know What I Mean so Yeah I Would Not I Would Not Do That Today God's Blessing Because Now You're in Your Center Help to This Said Again Your Products Help My Patients so You Come Full Circle without Definitely and That's It That Is That Is the Most Gratifying Part of of What I Sell Is That You Don't Unsolicited Patients Will See You in a Waiting Room and With This Particular Product That I'm Selling Now at Mean It's a Lifesaver Right so like Literally so Patient Comes up to Me This Is Not a Month Ago In the Waiting Room and Says You Thank You for Doing What You Do You Say My Life I Can Save Your Life Right but It Makes Me Feel Good to Think That I Know Made a Case for That Patient Advocated for That Patient in Front of Physician That Ito Saw Fit to Put This Patient on That Product and It of Their Life Is Improved Because That in Some Dramatic Way so That's the Big Deal with Travis That Was Ablated Not You Just Did Your First Half-Hour with Us on the Guttering Project We Have a Whole Another Hour to Go with Travis We Got Tons of Really Cool Stories about the Pharmaceutical Industry Will Be Back Here in Four Minutes This Is the Only 24 Hour Take Anywhere Platforms Dedicated to Food and Fun We're Spooning Our Townhall.com, Is a Thing or Two about What It Takes to Succeed in National Politics and President Frump Believes the Russia Probe Will Hurt the Democrats Politically in 2020 President Is Predicting That the Democrats Focus on the Russia Investigation Will Backfire in Next Year's Presidential and Congressional Races after Former Special Counsel Robert Muller's Congressional Testimony the President Said There Was No Defense to This Ridiculous Hoax Greg Claxton the White House Horace Johnson Vowing to Silence What He Calls the Doubters the Doomsayers the Gloom Steers You Don't Think You'll Be Able to Successfully Lead Britain Out Of the European Union The New British Prime Minister Is Held His First Cabinet Meeting Later Address Parliament Johnson Promising to Exit the EU by the End of October North Korea Has Fired a Couple of Short Range Missiles into the Sea off Its East Coast South Korea Says One of the Two North Korean Missiles Flew 450 Miles Longer Than Initially Suspected Soul and Set Both Missiles Got to That Distance before Landing in the Walters of the Country's East Coast the South Categorizes Both Missiles a Short Range but It Concerns As to Their Status Senior Japan Official Says If They Were Ballistic Missiles They Would Be Violating UN Sanctions on Charles the Ledesma Party Time in Puerto Rico Protesters Celebrating Afterword That the Embattled Islands Governor Will Resign a Week from Tomorrow Led by Strong Demand for Commercial Aircraft in Cars Durable Goods Orders Rose by 2% Last Month on Wall Street This Morning Stocks Are Lower the Dow Is down about 138 Points the NASDAQ Composite Index All 58 S&P Currently down 14 Points More on the stories@townhall.com Now You Can Fly Anywhere in the World and Paid Discount Prices on Your Airline Tickets Flight Today to Learn This Harassment to Read or Anywhere Else You Want to Go and Pay A Lot Less Guarantee Quality International Travel Department Right Now Low-Cost Airlines 800 452 1075 800-452-1075 That's 800-452-1075 Got an Old Car Donated Whether It's Running or Not to the United Breast Cancer Foundation and Save a Life They'll Even Come and Pick It up for Free The United Breast Cancer Foundation Has Saved Hundreds of Women's Lives through Their Free or Low-Cost Breast Screening Exams but Now They Need Your Help The United Breast Cancer Foundation Wants to Save More Lives through Early Detection by Offering Women Free or Low-Cost Breast Screening Exams In Donating Your Old Car SUV or Truck Whether It's Running or Not Helps Pay for Them Plus You Get a Charitable Tax Deduction Help the United Breast Cancer Foundation Save Lives by Donating Your Old Car SUV or Truck Call Now for Free Pickup 800-245-0823 800-245-0823 800-245-0823 Call Right Now That Number Again Is 800-245-0823 Never Forgotten Apparel Is More Than Just a Premium Women's and Men's Clothing Line It's a Movement to Remind Us to Where American-Made and Serve Those Who Serve Us Our Heroes Never Forgotten Apparel Gives 20% of Their Total Sales to Nonprofits That Support Homeless Veterans and Off-Duty Firefighters and 50% to Individual Veterans and Firefighters in Need Nationwide Checkout Never Forgotten Apparel.com Use Promo Code Matt and ATT And Get 15% off Your Purchase Will Go Back into Our Number Two Check Project Episode 18 on Their Clear Here with Your Host Dr. Ken Brown in the Course Today We Have the Generic Pharmaceutical Rep Travis Page Real Quick Don't Forget to like and Share Gut Check Project Go to YouTube.com Search Gut Check Project Then Be Certain to Subscribe and Tell a Friend Then Go to Get Check Project.com Go to Contact or Connect Let Us Know That You Did It to Be Entered into the Contest Where This Month Next Week We Give Away At Least Five Signature Pack 10 Troubleshoot the Signature Packages I Have Heard You Talk about This but It Is Change the Time Two Cans of Copenhagen's Good for Your Patience I'm Glad That's Better Than That to Be Month Supply about John Teal and Katie Being CBD Paired Together and You Get to Choose Your Flavor like Natural Natural like Sentiment Gets in So It's, like Opening You Choose Your Flavor Yeah Yeah Signature Package, like Copenhagen Be Sure That Is Now like Travis Are Coming on Your Great Salesman Genesis I Was of Delta Here Is a Reminder Ever since the Invention of the of the Phonathon Wonders for My Hemorrhoid Business and That's Why so This Is My Public Service Announcement Don't Red and Poop Because You Get Him Yeah That's Public Service Announcement How Does like the Fact That Friday Nephrology's Toilet This Is Weird That's Gutsy That's Her Mascot Yeah It's It's Cool That He Can Also Articulate His His Hand to a Phone and He Uses the Potty but Now It Away This Is What Amphibians Do Nowadays This Is with Her into Everybody's Evolving Everybody Is Evolving See Evolving so Tribes You Had Quite a Change from You Went to If You Had Mentioned Earlier That Lady Said He Went to Stephen F Austin Kratz Yes Sam Foster State University down in Nacogdoches or East Texas and Currently Now You Live in Crom Which Is Just West of Denton Texas Correct Correct and You Did Not Leave Your Team Roping Skills behind Is Part of Your History You Just Lunch Would Expand on That You Have Any They Do That Anyhow Yes so That in Our Roadblocks in College and We Always Thought That the Timed Event Guys Are Kind of the Sissy Guy I Know I Just Turned out They Were the Smarter Ones Right It Really It Really Does Turn out That Away You Know Your Your Career Is Is Prolonged Quite a Bit You Know When When Your Mount Is Not Trying to Put You on the Ground Hurt You You Know so It It Was Very Much Considered to Be and an Old Man Type Thing by the by the Rough Stock Guys Will Now I Fit That Bill Right Side Zero Shame about about Team Opening It's Actually Extremely Complicated and I'm Rude I Learn Something New Every Time I Go about so It's Some Guys Fish Some Guys Play Golf on Llama Pharmaceutical Rep by Trade but My Hobby Is Timo Days a Week Do You Do T-Mobile or Do You Work on It Yes so It's It's Tough Right Because of You Know All the Resource That You Need to Actually Practice Something I Have You Know What a Dummy If You Will That I Can Roped It Stationary That I Can Do by Myself All the Time but to Actually Get Rigged up and Get on a Horse in and Have a Live Cattle the Rope for Me Not to Be Someone You Have the Cattle Strictly Roof Yes so This We Just Built a House Last Year But before That I Was on a Real Property That Actually Had the Facility A Roasting Pan on It and so We Would Bring Cattle Lisa Basically to This Facility but We Have A Lot Of Space Sure so You Go Online You Start Trying to Leave Lease These Corian Take Cattle What They Want to Lease 100 up We Have Space for 100 Right so We Needed 5 to 10 Generally Be Whole Lot Easier If He Had the Hundred in That Same Space and I Was Going Fishing in Lake Geneva Was Starting Okay That Would Get Really Complicated in a Hurry Bill out Would Be A Lot Of Moving Parts Anyway since We Figured out That You Know There's a Market for This Bird You Know the Small Group of Cattle so My Idea Was on My Little Place to Raise Five and There's All These You Always Have Five Babies on the Ground That Would Mature and and Be Able to Be Leased out to Somebody's Facility and You Drive up down 380 You Know You're from Decatur You Know What I'm, There's All These Little Farm and Ranch Is There and A Lot Of Them Have Team (so That If You and and and Their Alts Smarter Not Hundreds of Acres Right There There 8 to 10 so Not A Lot Of Space to Keep a Bunch of Cattle so That Was My Idea so I Got And Just like Everything Else I Get Myself into a Little More Complicated Than What I Thought You Know It's A Lot Going on This for like I Think Is My Fourth Year and Raising the Yeah Yeah so I Started out with Two Mama Cows in My Idea Was to Breed Him and Then Turn out Babies Will Eat You Can Only There You Can Only Keep Him Permanently If Their Female Right Because That's the Only Way to Make More Cows Right Is to Have Female so If You Have Males That Doesn't Grow Your Herd You Know What I Mean You Can't Bring Them Back to Each Other and I Can't Think so It It's Been an Endeavor Right so Were in the Were in the Process but Yeah That's Another Aspect of the Hobby I Guess You Have like a Career in the Dating Apps with the Yeah Yeah What Side of the Body Corian Table down the Road so You Know Every Every Winter I Take Him on a Date Hello Demo Gals in the Trailer We Take One or On a Day over in My Buddy's Place Even for Them Swipe Right around and Only One so That They Are A Lot Of Choice on a on a Quick Side Note We Talked about This before That When You Have Too Many Choices There Is a Psychologist That Did a Site Psychological Study Were People Who Chooses Many Types of Jams That They Wanted and Had like 40 Different Kinds but You Could Bring Her Back Didn't like It or They Could Choose between like Three And He Showed That the People Had More Choices Were Less Happy with Their Choice or with Their Decision and the Other Ones Didn't That's Exactly What I Think Data Gaps Are I Think You Should Download an App and You Go One of Two Choices That Are You This Guy like That You Pick It and I Think People Would Be Happier Person I Don't Have Any Experience with It so That All I Not One Time Have I Ever Had It I've Always Had You Insane the Natural Old-Fashioned Way Right so I Don't Even Know What This Means This Online Anything I Don't I Don't Get It Never Participated in Also You like Me Look like like the Old Way like like OkCupid Original Apps like I See You Are and You Always Are I Say Something Funny You Know and Then We Dance and Then We Have a Beer and That's It L Next Week and We Go to a Movie like a Real Relationship But I Guess This Is a Real Thing Will Go My Point Is How Unhappy People Are And I Think That Deserves That Foam Well There's Always a Sphere of Zero Something More to Be like You Could Choose You Driving down the Elders Bolted Usually with That Will Make Better You Know Kids with This Was the Swear That That's an Interesting Concept What If If Back before Social Media If People Think of Everything You Give up to Put Your Profile on a Dating App May Not Only Do You Have How You Aesthetically Look but You Begin to Say Your Name or Your First Name out I Assume Sometimes I Do They Ever Ask If You Giggle the Deeper What Your Occupation Is WikiLeaks Which Hobbies Are but If You Just Had to Wear Shirt Just Said Your Name And Then Your Hobbies Where You're from And like What What Area You Live in and Then You Are in a Bar and Then You Begin to Weed out People before You Ever Got to Know Them Just Based on What Their Hobbies Were Never Printed on Their Shirt They Would Bay It Would've Made Things Just a Dating Shirt When You Compare the Hobbies of Everybody and There Probably Not Be Satisfied with the Fact That You May Not Find Somebody like Team Roping And It Just Because It Wasn't Listed on There so the Promo Comes from Looking at All This and I'm Not Seeing My Hundred Percent Match Here If You Have These Small Biographical Details but They've Done I Mean There's a Whole Lot of Evidence We Are Not Becoming Happier As a Society Affect Depression Is This Huge Which Is Why Think Things like Sulci but I Can Make a Big Difference Probably All These Drugs and Everything Probably Just Putting the Phone down for a Little Bit Is a Great Way to To Reconnect and Reset Which Is What I like about What You Do Is Your Hobby You Your with Nature Your Beer Interacting That's Awesome Well in That You Know the Contrast Is My 11-year-old Son Just Turned 12 He's 12 Years Old Now but Now He Is So Not Interested in That Aspect of My Life and When I Was Growing up What a Kid Because I Didn't Have It You Know What I Mean I Ate Was All Indirect It Was Adjacent to Me Was the Influence Was All for My Mom Side of the Family But It Was Everybody a Kind Move past It so I You Know When I Got into It I Can I Got into It on My Own so I Would've Loved My Dad to Be Involved in Something like That and My Son He's a Baseball Player This Thing This Is Not but He'll Pick up the Phone All Day No Enemy Ill Be on That PlayStation but You Know That's It's Just Completely Different from When My Experience When I Was Growing up Totally Can You Explain Exactly Were Saying Team Roping You Know I've Never Watched It I Don't Know Just Tell Me What You Do Okay so I'm on That I'm on the Head Side Right so It Set up This Away There's A Shoot in the Middle Where the Callous Deployed Right in on Either Side I Shoot There's a Box so the Cows Deploy to Get a Head Start Right and Then It's Basically a Horse Race Right so the Guy on One Side Is Responsible for Roping the Horns the Other Guys Responsible on the Other Side for Coming behind and Roping the Feet And Then yet You Dally off Your Saddle Horn and Kinda Stretched Tight for a Split Second They Drop a Flag Not Your Time so It's a Time to Vent Animals and Hurt Not at All Not at All Not All Yeah so There's A Lot Of Controversy Sir Surrounding What They Call Tiedown Roping Where They Use Sprite with a Flip Them over so There's a There's A Lot Of Controversy and Not Just the Way It It Looks I Think Team Roping Is A Lot Less Shocking but You Know That the Bottom Line Is Is That There's All Kinds of of Regulation and That Kind of Thing to Make Sure That That That the Animals Are Taken Care Of and I'm Telling You This Those Horses I Would If I Could Come Back Is on My Want to Be High and Horse Absorbed a Performance Horse of Some Nobody Lives Better Than I Did Have a I Had a Friends Family That They Bread over the Cold Cut Horses Big Big Big Money

women american amazon time money game world movies business uk man technology men work college talk running training change stress pain doctors career friend thinking project story food sharing writing gold wild fire sales toronto mistakes european union market development diversity mind north carolina movement cost drive missing study south habits birth greek weird environment high school trade budget island horses patients launch playoffs wall raising human phone skills players diet attention drink beer alaska advent medical idea kansas sea blind hurt childhood heard deep dive position beach improving roots reddit couple picture mine behavior integrity comparison phase calm dinner sexy cult app front math effort hobbies alzheimer's disease fellowship lego points cannabis finish succeed incredible paying eat ends breathe degree wilderness cbd bar construction lol ipads car exciting habit drug exit shoot presidential google play san antonio foot waste views commit weed louisville east coast recognize costs bed bucks advantage gas deadly account physicians cancel primary convention landing epidemics floor poop lives representation mushrooms desires gut gross paint forced pattern regulation promoting flat fell arm correct omaha requirements covered function americana horn invention app store little bit spike dating apps outcome facilities last night industries presenting firefighters implement weeds compete fascinating copenhagen gut health big deals mic bit resident ridiculous tolerance farms good time mother nature lose weight small town prescription next year blocking really matters my life other side cura eis rope tron amount texting earned leases pie side effects pharma kpmg essential oils looked way back masses bacteria patent walters sphere brakes walgreens cattle weight gain horns hundred pizza hut massa tie conductor interstate exeter gainesville small groups produces clinical trials keyboard influence people merck listed denton pharmaceutical manner intrigued tab make friends specialists rhymes sheet autoimmune disease golf courses dealt primary care six months occasion new habits go ahead kb personality tests injection know how go get potty help people waiting room marker soit your heart your brain doubters last one percentage ade floors each other capability western civilization east texas gastro foresight solaris circadian rhythm school bus many things same page bloating poisonous artie referred roper great ways revitalize believe it pringle flipside hypothyroidism med school raise money number two hamburgers aig molecule best use leech gallon restructure i won gazette precursor last decade it doesn my head conference call his house heart rate car talk absorption micronutrients early detection state laws be sure enzyme only way different kinds great job gloss keep talking take it vo2 somebody else aggregate always good cvd boiler making fun whole thing pharmaceutical industry gladwell that guy day program be heard know me different people old way make it better capsules not okay big fan thanksgiving break guile daily basis scone what works stave mind right my friends twentysomething what it takes he said troubleshoot district manager really cool ardmore your phone quit drinking my own construction company kpd hellhole all kinds drug companies national politics sexiest man dropping bombs gonna be pizza place pocketbook do anything zzz show how ronnie coleman congressional races polyphenols great example fecal transplants free for all roping powers that be five weeks nacogdoches save it congressional testimony claritin you were born we play win it mean it ken brown speak spanish retort motor neuron disease company name my buddy be able probably not dietary fat research triangle our business does it matter that kind been told what you get it was all being able doomsayers amsoil old you that moment team roping this program present value her shoes far more i think it both ends will have her sister future it your position your price put you prostaglandin atrantil be involved outdoor magazine arbitron sarah jean i keep i mean it all just commercial aircraft your ticket my butt you drive where you are now unitech me not you begin be professional i looked cyclooxygenase i called you living i give it yeah is

18. Dr. Kenneth Brown on gut health, SIBO, and creating Atrantil

Gut Honest Truth

Play Episode Listen Later Jul 10, 2019 68:44

Katie and Jen speak with board certified gastroentrologist Dr. Brown on gut health, treating SIBO, and creating Atrantil.

#113 - Facebook Groups, IF For The Elderly, Foods To Open Your Window, Food As Fuel, Macronutrient Freedom, Clean Fasting & More!

freedom fasting fuel foods groups window elderly macronutrient atrantil

Play Episode Listen Later Jun 17, 2019 60:38 Transcription Available

Visit IFpodcast.com/episode113 for full show notes, links, references, and more! JOOVV RED LIGHT THERAPY DEVICES: Use The Link Joovv.com/IFPodcast With The Code IFPODCAST For A Free Gift! 10:40 - ATRANTIL - Use The Link Lovemytummy.com/ifp With The Code IFP, To Get 10% Off! 14:50 -Listener Feedback: Annie - Finally Seeing Food As Medicine And Fuel, And Accepting IF As A Way Of Life 14:50 -Listener Feedback: Lynda - Thriving On PUFA 22:55 -Listener Feedback: Alex - Macronutrient Freedom! 27:10 -Listener Feedback: Maria - Success With The Clean Fast! 28:40 - GREEN CHEF: Use The Link GreenChef.us/IFPODCAST75 For A Total Of $75 Off - That's $25 Off Your First Three Boxes! 30:30 -Listener Feedback: Abbe - What Foods To Open Your Window? What Foods To Eat? 36:35 -Listener Feedback: Sally - How Many Elderly Women Do IF? Could You Create A Facebook Group For Us? For information regarding your data privacy, visit acast.com/privacy

Cooper Read, Digital & Social Entrepreneur, MAPS Advocate & Zendo Project Vol.

Play Episode Listen Later Jun 13, 2019 117:11

Cooper Read is a GREAT storyteller while his career journey includes playing college baseball, a surgical technician, an adventurer and journeyman, MAPS & Zendo Project Advocate.Cooper has tells how he found inspiration knowing that he wanted more out of life than what the health care industry could provide in traditional institutions. Also, a mention from Ken & Eric about how you cannot out exercise a sedentary lifestyle and a customer story about CBD and vagal mediated atrial fibrillation. Instagram: @cooper_readhttps://maps.orghttps://zendoproject.org/https://lovemytummy.com/spoonyhttps://kbmdhealth.comInfluencing I think during Re: did you want to stuck in a bad bundle get a great bundle AT&T vibrant DirecTV and get $100 reward card requires 24 month TV 12 month Internet agreement redemption required limited availability may not be in your area if you qualify.com/bundle AT&T that are subject to change new customers requires a minimum 49 and nine month 12 months after the price hiring secular Internet 25 minutes or higher minimum $40 a month early termination of return taxes fees and restrictions apply, visit.com for full details and it is now time for the gut check project you were here with your host Ken Brown MD I'm Eric Rager this is where you check your ego at the door because nothing got the table Doug can you do it for the person or the few times it is my title there MD so I'm here with my co-third-grader cRNA like that mix it up as you can tell I will do it different almost every single will episode 14 at what we are on episode number 14 that is correct so today we got a really cool desk alone and I'm super excited about this sort of things that you what I have done we get a lot of feedback from people that are been writing in is that we bring just on that were try to learn some stuff from correct and I think that almost everything will episode I become more knowledgeable it is expanded my mind I think today is exactly where we need to be because we have somebody who's a great storyteller that's got some incredible experiences just throws himself out there that's kind of a sort of how work, doing everything right now and if you're new to the gut check project I think it would you find that what can I both want to do out of the guest is find a little bit about their journey that took them to where they are now because life is a journey to find that you you're going to be satisfied once you know more about yourself and how you know what you want until you have exploded morality so exactly so work we have Cooper read on the show today and he is somebody who is really it's a lightning she actually inspires me and other people around him and he just jumps and of to explore different areas different ways of health and easily get into a lot of different stuff but if you're somebody who's kind of stuck in a rut right now this is your show converted to cover novel French stuff that I think is actually something that can change both health and mind yeah absolutely happy at think that Cooper has a great story of just being dissatisfied is where he found himself and decided to do something about it so allowable I'm not going to ruin his story that will get to that whenever he joins us here about just so happens that is doing something about it in a field that I have tremendous interest in and medicine is going that way and I think that we will all be talking about this five years from now as how really to improve mental health without question without question real quick of course if you also knew to get project and even if you aren't should always go to love my tummy.com/spoony where on the spoony network so/Bernie will give you are trying to heal outrun teal at a discount that you won't find hardly anywhere else so what is that all 20 oh that makes it so unique to Brown so this is kind of exciting this is my baby right here in a little shout out to Siobhan Sarna who is the head of the IBS SEBO SOS summit because probably much to her relief I finally got done filming my webinar for the experts on that is so nice and we got a chance to one of the reasons why I was looking at the other of future lectures and she's like you're the last one to do this of Mark Pimentel the psyche shroud it is we've got to know Tom Osborne that that is all these other people and Allison C Becker she's like you're holding up the whole show they yell for those who are into keeping the health and follow us and get the emails that we get every week that we send out just be sure and tune in because what Dr. Brown is referencing is see below SOS some and if you've ever been interested in why certain people suffer from G.I. distress and they can't quite find the answers that's kinda what this whole summit is about not everything is going to apply to everyone but there may be something in there for everybody who tunes in supercool about this particular summit and what Siobhan is put together is that you have people that have had different experiences doing different things right and my experience was in trying to find a natural solution for people with reputable bowel syndrome bloating change in bowel habits and that's how we discovered trying to with two trials which have been published and we been out now for about three years and the reality is worse in the same clinical results that we did in those trials which is 4 to 5 people to get better if you have the classic symptoms of when you meet you blokes now the other cool thing since we launched is that we have since learned through other scientists contacting us that the polyphenols in front your action extremely beneficial for you they work on an antiaging level there's data to show that you are living goes up which helps get rid of old and aging cells this data to show that you increase nitric oxide to the muscles so if you're an athlete so it's really exciting I started this journey to try and help people that were bloated that have bacterial overgrowth and we just keep expanding and knocking down your doors and that's what's so exciting about this I'll try to love my tummy.com/spoony putting code spooning SP 00 and why and you can also experience the so this is my baby show little support at least cash in one coupon that's that's your mission I want everyone to commit to cash in one coupon so that I know that people are at least realizing the importance of both gut health and overall health threat on the battery cell five for a friend or family member that may separate from my G.I. issues so I of course got check project like and share like and share like and share thank you for all of the new subscriptions we reached out to our KB MD health community for the first time this last week to introduce to them the contest where we are giving away to at least five winners the signature protection package of arch on tail whether it be with community CBD natural flavor or sentiment and keep those submissions coming get a friend get a family member to do the same for you like and subscribe to get to project either on YouTube or on iTunes choose an email through going to KB MD.com Sino community health.com and you click on contact sheet is an email it's easy that's all you have to do sign up and then in July we will be drawing at least five winners so the public to be more solid and make you kick the science this time why do you call that the signature package what do those two things blend so well together CBD and affronted absolutely no great thing that you're doing with CVD is that everything that you put behind this and this and I'm in if you're listening through the audio only I picked up both the CBD and the John Teal you have real cases that have come through the clinic and was shown improvement so using this combination is what you found to be the most predictable I guess solution for people who had some type of inflammatory issue and I won't go through all the different disease states but essentially combining the CBD with our Tron tale is the polyphenols and allow the CBD to even work better how does a Duke well there's a little enzyme in there that Decker dates are endogenous CBR cannabinoids like Ananda might for instance name FAH and good polyphenol intake actually prevents FAH from becoming overactive in eliminating the CBD from working were supposed to work exactly and so you're taking a science today but that's on, called the signature package they each make each other better and that's how come we teamed up to have the KB MD health CBD powered by Alexa absolutely so likes it like a chair guy got check project thank you for all the new subscriptions as last week that is that is amazing they tell us it would take at least 20 shows and were doing about episode 14 so we certainly appreciate it so now in a move into Dr. Brown what you have on the news topic for today well so on this topic first of all you couple quick shout out side I am horrible with time zones and we were going to have a fantastic Dr. Dr. Gabrielle Lyons she's a medical doctor in Manhattan she is a fitness expert muscle centric protein expert she did her graduate studies looking at protein she was in a call in and where to talk about peptides because that's my article to talk about little bit later peptides and unfortunately she text eventually gritty role in like oh time zone difference forgot about that and so she is a doctor so we couldn't get her to the work you have her own prolonged show trip organizer bring her here or would you be able to do it she's I think due to have a baby pretty soon so I don't want to have a new mom flying around like that which probably zoom her and but she's super smart and the reason why bring up is because we had one of our listeners asked something and this is right in Dr. Lyons were real house I was a said Trisha's email Tricia called in and said hey can you recommend a Kazen free protein powder now coming up soon in a week or two were to have another fitness expert named Max Fairchild she is super smart peptide expert he formulates nutritional products he's really the one answer that question Chris were to get that to you right away I can look it up but honestly go with the people that have already done the homework they've Artie tested it is the people that have looked at all the formulations were to find the best one for you so keep those questions, and it absolutely and did you have anything to add to video shot you on awesome podcast that just aired early this week I was I was on the intermittent fasting podcast with Melanie Avalon and Jim Stevens I think this is the second or third time a bit on their going on the dance anytime I think yes and yet the second time it's great we talk about fasting the lot more than fast we talked about fasting the medic diets we talk about all kinds of different things and I thought it was a great show and shout out to Melanie she's got a new podcast and I would be going on that on the well go one of the 24th I don't know when should you publish it but she's got so she has a hold of the podcast but that was really cool check it out intermittent fasting podcast and you can hear that episode and we talk a little bit more than just fasting it's those are two really smart people very very fun people talked about that's awesome I did want to bring something up to you I was reading a blog article from Chris Kuester here recently in a reminded me somebody member a little over a year ago there was this new message was being pushed out talking about sitting is the new smoking that's right so never talk about a sedentary lifestyle will if you remember it wasn't that long ago did tell you and I, laugh there's a lot of truth behind what you eat oftentimes you can't necessarily out exercise and what was that someone said you can't outrun the fork you can't outrun the fort that was it that's a shout out to somebody that we do have have in the show at some sometime the name Todd Smith is a bodybuilder trainer out of Omaha Nebraska he'll supplement stores and I heard him say that once like I am still sure what is is a lot of truth to that you know if you want to be healthy a lot of it comes to aware which of your food fuel source is is it healthy for you and what is that translate to so what Kuester was able to illustrate quite well is that if you're sitting for long periods of time throughout the day he can't really out exercise the damage that you're doing by sitting for this law say that again so so and this came in a blog from Chris Chris are who we know well and was your oven is great guy he wrote a blog all about sitting then yes he did any reference to a handful of studies he basically put together he does a great job of always aggregating different things that he's reading pulling great information making easy prey to can I consume but essentially showed that even marathon runners when they're not actively training is another there's other issues that may be going on with marathon running of long-term inflammation exposure anyhow but that aside there actually at more risk according to some of these articles he has and therefore coronary artery disease because of the long periods of times it they're not training and that are not running the marathon site are sedentary and that actually affects their metabolic rate from sitting so then you begin to die little bit deeper looking into sitting while working if you go to in office and you don't engineer of engagement your computer and your having to type for long periods of time you're still sitting obviously you're working you're working hard but possibly examine what would it take for me to get a standing desk or something similar that would give you some variability in fact Robert Hendrickson has a a new a new product that easily come out with rover that we had on from full bucket health that's right after the show he was sure the silver color prototype to have some sort of portable version of that so that you can get away from just sitting all the time you admits it's brilliant anyway it solves a lot of problems of course it gives you a portable office that you want to go but at the same time you now have the availability to not be confined to sitting while taking care of work will essentially what Christer pointed out is sitting for 11 to 13 hours a day and many people may say when I don't do that I get more than that and you may think that but you drive to work and then you put in 6 to 8 hours of sitting you wake up you set out have a cup of coffee and follow up on whatever it is you do you come home drive to work you may work out but that is a matter because they can sit down to eat when you sit frequently and then you sit down to attitude to maybe watch program at home before you go to bed that amount of sedentary non-movement over time as an aggregate the you simply can't out out exercise according to the studies well it's interesting because if you sit for more than six hours it's been shown that your lipoprotein lipase actually goes down and that's what burns fat you can actually have a decrease in your bone mineral density leading to osteoporosis and then ultimately increased coronary events due to high blood pressure and coronary artery disease than when you stop and think about it sitting is not very good. And if you look at how we evolved we really didn't do a whole lot acidic we were always on the move around so let's come up with some ideas right now we want everybody to at least try for the next week to sit there and do the so when you're put a timer on your desk chair or timer on your desk I think about it you can elevate your desk a little bit that there's all kinds of different options out there for you to do it what if you if your teacher if your teacher and you feel like that you are engaging the students on a particular subject maybe change the scenery have a walking meeting don't take the elevator if you can take some stairs what else oh I was just thinking that the first for the whole teaching thing to remember the meeting that we are at in Utah with the bathwater, and one of the moderators before they even began made everybody stand up and shout around guess I just get energy upright just get everybody moving and then that's how she said she starts all her podcast like that she makes her guess do that just to get them up and ready which is really cool so anytime you get up and do that I think that elevating your – we walked Wenatchee had a patient from Veritas the big company that does this trip we walked around my office and looked at different ways different deaths we can do for the employees last of it with this be something you would like and they were all unanimously really interested in that unlike Robo was talking about he thought that would be really difficult the beginning but suddenly he's standing for eight hours doing all his work no big deal at all none at this temperature and it don't you find it days it weaned up having to pound away a lot of computer work compared to the days were doing a lot of scopes are you doing a lot of clinic visits I have more energy after doing all the movement throughout the day than I do when I'm what's up once a month twice a month I just have to kind of pound a lot of work on the computer those of the most draining dates to me in it and I really didn't move I just sitting there panning out on the computer and its signage oil will melt let's just throw one other thing in there so people sit that they sit all day than they come home dad and then they get on their computer the blue light now your jacket up your circadian rhythm and I mean where really try to kill ourselves and like everything that we do in life right now is basically shortening our arches our health time is really what it's doing we have this were doing those other things to try to correct it but these are all easy life hacks that we can do get out wake up one of the greatest depending what time you wake up wake up really early so the sun is out for the greatest things you can do to turn your circadian rhythm is get up go for a walk on an empty stomach with sunlight to convert the vitamin D you turn on your circadian rhythm you're telling your brain were going to do this and it does a couple quick things number one you get your body movement to get out you little sunlight and you not waking up and immediately sitting down which is what a lot of people do and you know what I'm I try to do this I wake up every morning really early and I make my coffee in the French press and I got my little routine habit or routine is pretty important if you like a lot of people like Tony Robbins of the people to say Arnold Schwarzenegger like really highly effective people they'll have a very specific morning routine chair Tim Ferris Joe Rogan all that I will sit there and start regular coffee then work on the charts I took it one step further and I got a vibration plate I tried to stand on it and I should do my truck; unpacking this setting was it turns out it's really hard to do computer work with vision vibrating (32 oscillations per second or whatever so you have noticed in those vibration plates are kinda interesting but if you lock your knees out man at that there really affects model skinny legs I just take the population straight up to my eyeballs I can't hardly see much anything that so just simple access something that will go talk about in the next half-hour is going to be a another hack I was listening to one of the greatest biomarkers of all time Ben Greenfield, he talks about migration place he talks about getting out or talks about the get some sun they were talking about peptides which is really what I wanted to have Max Fairchild on in his you come back on here in a few weeks to talk about peptides and that is another little hat these are all things you can do that aren't that not that difficult to really make a big difference in your life and offset some of the stuff so fierce that they're stuck in traffic or if your sit in your cube: every time you stand up your bosses sitdown or your student teacher says sitdown there's ways to get around it just make sure that when you have it under control you can do all kinds of stuff were going to be talking with Cooper about different ways to engage with nature also data that's another little way to get your brain stimulated to get your circadian rhythm and track and all that definitely ending of these these are things that if you're a member of KB MD health here pretty soon Dr. Brown his mood coming up of the system where we can start putting together some of these small tips that were finding out basically just amassing these studies and how you can take these into practical life managers hearing this morning I work at XYZ I understand it's tough it's up to make a change what we want to do is see if we can help people find easy modifiers to make those changes meaningful to you and a little teaser may be have it delivered straight or maybe have it delivered straight to your home is by building a news coming out about that over the weekend so if you are on KPMG health.com and they are member of KPMG health look this site no later than the Sunday maybe before but probably no later than the Senate would get a really really really cool announcement on something you been working on for well over a year well over a year with some really smart people out there shout out to Mr. Zell of course but there I want to make a difference in my community sure and I think this is a way to do it and I'm really excited to start implementing some leasing's meeting other experts do all kinds of stuff and you would be Sony and if you're not a member of KPMG health aide cost nothing you said to go to KPMG health.com Pan down on the button on the poorly designed website that basically have no about myself and about we are working to prove it we brought in and we have an intern in Internet started this week we have someone who's actually going to help us do stuff thank goodness yes thank goodness that read had to find somebody that's like half our age to do that I am super excited to have someone help us get those things done and he sees already off and running in and helping as the redesign so that will be great speaking which I need to address something you know that the processor is you write yes so several of you and by several I mean a few hundred of you have not have had issues while trying to make purchases through the website on KB MD health and it is truly no fault of ours it's two healthcare people try to run a website but the processor since we do process CBD sales all of the banks collectively have basically come up with new parameters that you have to be vetted and you have to have a right processor they're basically trying to prevent fraud so for every reputable business is about 20 they just aren't there try to weed them out so we're it it's it's inconvenient for us but were were getting through it and I've been kinda forced to handle it in the evening some phone calls from some folks so that we can do some manual transactions not a big deal though and not all bad has come out of it I've met some great people some great supporters some people just have questions knowing you like I could totally see you know it's not bad in fact I'm been invited to several weddings and onto a vacation with whatever whomever they are but I did get interesting call I guess it was three days ago from a Jonah from South Carolina and he's been watching the show because his daughter who lives in Houston found found the gut check projects weight and they been sharing it back and forth they like the episodes well he's now customer of KPD health CBD but he wanted to tell me specifically about what CBD was doing for him and on a moment to full depth on this with you but vagal mediated PVCs that was basically where he was coming from he said that his vagus nerve in his interpretation of it was that over vagal stimulation in even even in that I I'm still trying to wrap my head around it but would elicit PVCs and throw him into a fit and post and say the vagus nerve is a exquisitely complex thing that runs from the brain all the way down so were to have a vagus nerve expert what outpatients that's his work as a PhD he's working at vagus nerve stimulation and what it does and where can go so we can that's good that's a whole separate episode but I love the fact that he called and why do you think the CBD helped him I don't else really good question his his interpretation was that something with the vagus nerve whenever it wasn't performing properly he could have PVCs and throwing himself into a fit but something that he'd found out is that using high quality revocable CBD dose actually prevented him from having a fib episode taken last summer between 812 hours 28. Go in a fit anymore and he had the same experience so far with KB the CBD which I thought was great in a course is anecdotal's are not making a claim but this is what he's found utilizing that he's been in in conversation with his with his cardiologist to talk about that but all that aside I would like to dig in deep with within the course the vagus nerve is it's think that Vegas is Latin for wanderer it's a nerve it is the peer sympathetic nerve is a great regularly because all way down and regulate your gut as well and it's interesting because even in the SEBO form committees and things people really try and make some sense of it they try and figure out how to manipulate the vagus nerve words can bring one of the world's experts on church to do a deep dive real geeky scientific dive into it to make sure that your vagus nerve is hopefully the beauty of CBD it works I can adapt to gents which credit goes where you need yellow you get the faster time goes by that because that's another half hour so episode 14 will be back here after the break with Cooper read in just a moment why have thousands of aspiring authors teamed up with Christian faith publishing to publish their blog because Christian faith publishing is an author friendly publisher who understands that your labor is more than just a book we provide authors freedom and flexibility throughout the publishing process professional book editing award-winning design and some of the highest royalty structures in the publishing industry and is always you will retain 100% of the rights to your book I was looking to find a company that I could trust one that assisted in the editing process completely Christian trade publishing will publish market and sell your books in all major bookstores and online booksellers as well especially Christian bookstores call for your free author submission kit 800-978-4812 800-978-4812 800-978-4812 that's 800-978-4812 never forgotten apparel is more than just a premium women's and men's clothing line it's a movement to remind us to where American-made and serve those who serve us our heroes never forgotten apparel gives 20% of their total sales to nonprofits that support homeless veterans and off-duty firefighters and 50% to individual veterans and firefighters in need nationwide checkout never forgotten apparel.com use promo code Matt and ATT and get 15% off your purchase Dr. Kim Brown here host of project with my cohost Eric Rieger I've seen in my practice that I tried to as a whole lot more than just the bloating product yes it does a whole lot more than just exploding because the polyphenols if you find in Alicante what are some of things these polyphenols do affect these polyphenols can help you have more energy and polyphenols are great it sounds like it's good health: more people than just loading go to let my Tommy.com/and we are now back for the second half hour episode 14 gut check project I am now joined on my ride by Mr. Cooper read digital entrepreneur and social engineer Adaline Cooper doing very well guys I'm happy to be here so you're also a maps advocate as well as the fun I'm going to screw the name of Zenda project I volunteer correct absolutely as in the project and maps organization the multidisciplinary Association for psychedelic studies you have an advocate for that can push that but I really am a volunteer present no projects yet what is what is on the project and the project is a project it's underneath the maps organization they set up the arts in music festivals all around the world and again hold space for people that are having difficult psychedelic experiences that have story after story was the reason why want to have you on so bad is because I really do we we've actually interviewed Dennis McKenna who is a godfather in psilocybin there are in my world there are no FDA studies going on with her looking at suicide but for different things and were to jump right into your history as soon as I countertop but we always try doing the shows at least we get through one academic paper to get everybody up to speed at least on something try to teach something so there just yesterday the US news to know the report where it showed that US death rates from suicide alcohol and drug overdose is reached an all-time high so I think there is no better time for somebody like you being involved with the maps to start integrating some of the stuff because were clearly not doing a very good job were committed suicide more often were dying from opioids and all this so what I wanted to get into on the fringe a little bit is something called peptides so I am not an expert in peptides of Max Fairchild is Gabriel aligned Debbie alliances that we were talking about but so I try to teach myself a little bit about this and so I found an article on a peptide called BPC 157 soap BPC 157 is a peptide chain consisting of 15 amino acid so peptides are just very specific amino acid and Ben Granger was talking that when does a peptide become a pro to Mauritania yet and if there's there's really do know the experts on this can say well it gets really weird because growth hormone is still considered a peptide but it's really that it's a really big peptide so that it's just very specific amino acids put together so BPC 157 although it's considered synthetic it's actually a protective protein which is found in the stomach and it's known for its anti-ulcer effects of the known about that for quite a while Dr. Lyons is the one who told me to start using my guest wrote you practice I'd never even heard of it nobody ever talked about that so I'm super excited that I'm now getting into this aspect so researchers are conducted numerous rodent studies that show that it doesn't protect against of protective effects but it also seems to extend beyond the stomach and intestinal tract so BPC 157 has been shown to benefit ulcer healing the stomach intestinal damage such as fistulas and inflammatory disorders but there is some anecdotal evidence to show that bone and joint healing also takes place what I really wanted to get into is in my practice I talked about the brain got access all the time so I found an article researchers out of Croatia have done rodent studies looking at the influences on the brain got access and this actually comes from 2016 and what they did is they looked at DPC 157 and over a very long period of time they tried to show how not only is it protective in the stomach but it is very useful as a peptide in other areas of the body specifically the brain is funny because their thought on this was the first auditing to think about this when we top of the brain got access in the first one actually show that was Pavlov I have lobby and respond Escher fistula in the dog ring a bell here's it turns on the intestines that's a brain gut response yet is so we all have this and so the main thing that BPC 157 does it is a growth like peptide so it turns on genes that increase blood vessel growth and nerve growth since we were taught to draw ever is if you're like me going what BPC 157 turns on blood vessel growth and nerve growth while that's while it has wild so wild so what they did as they looked at a bunch of different well brain mood issues and I specifically looked at these animals and so how does BPC 157 help with this/want to go through in the articles really Berrigan charity coupons along so I try to go through a few things because if you suffer from any one of these but start talking some peptides okay depression they proved that BPC 157 actually acts on the dopaminergic and serotonergic systems as well as the GABA system member a few episodes back we talked about how CBD can directly bind to serotonin right much like an adaptive gent it's almost like this is adapted and also they show that in these animals they induced depression and I don't I really get into how they actually do this with the animals on and off they served with divorce papers nudging winter jobs only or that you like the big firearm then whatever it something you know I can't sit down for too long so actually induced depression measured all these different levels and they showed that serotonin and open dopamine and GABA all came back to normal levels after being injected with interesting 57 okay super well, this will alcohol withdrawal they showed that it actually counteracted acute and chronic withdrawal as well as healing the liver and the G.I. tract that is very interesting but it makes a lot of sense on why people can't escape alcoholism oh one step further opioid withdrawal allow just kept on saying you with death rates from suicides alcohol drug overdose will result in high and what you're going to talk about as some psychedelics have some great promise I'm learning about this for the first time and I'm reading this albeit animal models but it's very hard to get FDA to approve human studies we know that so there has to start with animal models sure it showed that the opioid receptors would be down regulated after getting it so that they didn't have that yearning with her like demanding the opioids that's that's actually really impressive then it gets into disease states multiple sclerosis BPC 157 effectively counteract the development of brain lesions and MS induced mice traumatic brain injury they actually stimulated nerve growth and decreased brain edema after inducing try to bring injury spinal cord injuries it improved rat tail movement after the end because a spinal cord injury so basically this is what I really consider a true life hack if it difficult this can be put over that's what I want to have his peptide experts on so I have not use the personally I've not given it to my patients yet to them just discovering this but when we start combining these different things sure it's a natural immediate well it's a synthetic amino acid sequence but these peptides the really big in the bodybuilding community the really big and antiaging community which sometimes I've always said that I felt like endurance athletes and bodybuilders know more about nutrition than any gastroenterologist they manipulate the body through sure so what we talk about here and you're going to carry the torch now because what we talked about is some pretty cool stuff like we've covered stem cells CBD photo bio modulation these are all easy to implement things that can make a huge difference in your life so I was looking at the star some Facebook groups that are that are really proponents of peptides and I will set a couple emails on that question to have no like right now whenever for Max and just for us to come to think about something that we have the answer specifically from the research that that we have I know before Shire for 157 but what makes it synthetic and is there a is there a natural counterpart that that does that and the other one would be with all of the the advances are the disease states that we talked about would benefit from what about peripheral diabetic neuropathy if you're talking about our generation and blood flow in an angiogenesis or growth of blood vessels and that's that's ultimately what ends up you got get there poor guys got diabetic neuropathy in his feet and he is sitting too close to floor heater and burns off the ends of ends of his toes he can feel it or or starts taking Lyra cover gabapentin or something and you know all those commercials yeah cause depression above the head falls off to me all those things so what makes it synthetic I did I had to look this up on examine.com it's considered a 50 amino acid sequence it's only considered synthetic because the particular sequence has not been extracted be in the exact sequence it's probably believed to be a large one that gets cleaved that works on the side of protective area of the of the stomach so it's only synthetic because they've not been able to actually extract it in the exact same sequence from a human possible that it lives somewhere even if it only for a brief period of time we do seven found in its whole form yet exactly it's like many things that you know you can either I've had this I've had this discussion with different pharmaceutical companies where when you look at that will say oh it doesn't get absorbed with the be like systemic effects in the argument from the pharmaceutical company is owner but when you take our drug you won't see this in the blood in my argument is when you eat a steak yes he stake in the blood yeah right you break down ESU and amino acid complex and that's that's that's one of the things actually happens to do pharmacokinetic studies they say oh take this is it in your blood doesn't get absorbed okay white why my feet swelling wide what are right I heard or whatever you that since the whole prodrug to active component thing you know it's basely taken in this hold this this is and what's going to the action it's when it's broken down or assembled into something else that is in the doing whatever it is yeah totally so BPC 157 were to learn more about it and when we do have a real expert on about that I'm just can eat his brain and just or her right however the expert is not only messy that's just some work I just subscribe for shares are welcome to gut check the project's mess so speaking messes I don't know while that is even a good segue really at all so I think that we should go ahead and not reconnoiter here and go read and reread and reintroduce Cooper Cooper read I like he said he is a digital and social entrepreneur now that you found use your way there in a completely different career path and where we probably may have crossed paths early before didn't but didn't really get to know each other right right absolutely no born here in Texas I was born here in Texas small town grew up in Paradise Texas tiny little you know I know there's a dot for paradise but it's out of nowhere here in North Texas and then now what where did you find yourself after you are you left. I yeah so died I felt paradise when traveling around for you know I get a plate a year of college baseball Texas Boston University in the know then I went in the Denton and got really to the arts after my baseball careers have over from there I decided I wanted to go into performing arts so went to Dallas got a degree performing arts and from there I got opportunity rip Chicago studying commie and no second city in the improv Olympic up there just to show talking about your your life is one of the comedy cards like you to say offensive stuff and just blame it on the company joined the professional comedy Association it's much easier to get into the actors Guild yeah yes I like what if about you to the cards always want to do it whenever I offend anybody absorb what you say yeah right as it I don't mean it this material anyways and from there I became a father and came back to Texas and had to get a real job and quit bartending in and doing comedy stuff on the weekends got into the surgery technology that assert became certified surgical tech and started my career in Denton and then moved to back home in Wise County Decatur Texas and wise region there specializing in euro spines in Branson orthopedics will you that orthopedic so you know he worked with one of our former guess right would that be Dr. Wade McKenna yes Ashley work in Canada several cases it had II have a very just so many fond memories working with that guy he so good so talented what he does in and then his you to ongoing research and education for himself and just what he does is just awesome I'm a big fan Dwight McCann I like to give them a shout out some point and say hello where he says hi you were actually huge fans also when it when he came on the show I thought that was one of the coolest if you have a chance look at that episode whatever number whatever number that stem cell self there is something that you did look at did you ever do it who did you assist him in any stem cells are to do only just do the open cutting stage and open cutting staff you know and then he would get in and then you'd spin the plasmon stuff in and re-administer that no one's closing was done to help with the healing and think that you know like that after he was doing that in the MLR PRP experiments to hear he had his own centrifuging at using one or two dedicated people there they were just there is basically a mini lab and rail are right in the middle of the signing Alec while we were doing the casing I would be spinning that the PRP and separating all that and then at the end of it it was a know what the assist job or whoever was helping in a close up the case they would administer that for a for you know the healing process and regeneration goes on that is really cool why Nancy was into any course she had added to awesome ortho's there have chronic and repair of the asset I spent lots of time working with Dr. Barrow he's these were my favorite surgeons is a great great position and a great guy and generally you know just anyways those guys and in his first assist is her sister Jacob has been with him many many years is one of my best friends and and I super sharp guy and also super fun and really get another college baseball player yeah yeah so it sounds you had a great environment right there did something happen what you dislike said screw this through down the live trocar or whatever it is take off and walked out or what happened so I really I wasn't I wasn't happy or fulfilled after certain amount of time you know I like I said I was in Chicago studying calmly all the stuff and then I was like okay what I get a real job raise a family do that sort of thing so Jacob Mayberry invited me Dino to his okay maybe should come check it now follow Romero and I in the case and see if you want to go get certifies of something you want to do and so I did that audited today with Barrett Ruth Rivero at Bridgeport and then from there is like a family survive and do this for a while and then you know several years ago I know that for five years and I start to just kind of check in with myself and realize that I'm not not happy now at my home life I'm looking back on now might be a little bit of depression you know I had all these great things going on had a good job is in a happy I like the people I was working with but you know there was just I was tired. He didn't have a creative outlet I didn't have that outlet now you did know if you do the performing arts than comedy you've got that brain that needs to constantly be stimulated like that right right and so when in surgery became so monotonous so robotically you know do insane things and you know I I rose up to be no really good you know in the in the spine and euro area and then and even that you know everyone like I'm helping people you know it's fine brains working on that and that's awesome that's exciting I love it but after a while I just knew that I did what I wanted like my heart was call me to like be out and about and go moving shaking and then but as my my health started deteriorating as well with liquid like to the 50 and that the depression and asked her to gain weight and really was the unhappiness with the way in all not really unhappiness with the way but just like the not being fulfilled and being unhappy plus the weight gain had every check in with myself and figure out what was going on there so start taking steps to get healthy so let's look at that what how you think that you ended up becoming unhealthy in that environment because unfortunately we see a lot of people in healthcare and I think there's a lot of reasons for the hours stress the shift work all different cards think so our healthcare providers sometimes are sacrificing themselves without even realizing it to try to help other people how do you think that process happened with you I'd I mean I agree I think that's what it was he knocked the long hours the unit with its physical work here on your feet you know 812 hours a day that's good thing though now that's a great thing to be moving but once you know that the long hours and just being of exertion with the mental exertion as well you know go and the emotional you're working with people you're trying to save lives here you know and so they take their jobs very seriously so mentally physically long hours that will sale that do you say that standing in one spot you leave your working as the technician and you often times especially in difficult case your holding a pose for a very very long time something being articulated something being cut out and you really are sacrificing a lot get you get aches pains etc. you probably absolutely accurate is this holding these Sina you want to move so understand back when I was a med student we had to do that yeah and you like a member universe aggressor redoing a gunshot wound like 2 AM in your hold his retractors and you start getting fatigue start shaken surgeon starts yelling at you like trying yeah three a little bit of sweat and I hope it's not going to fall into the sterile field you know yet is all kind of distress is that going on yet for sure but I think it's so over a long period of time I think that that that weighed a lot on me just with the stress that goes on with the environment and in that and then justly and not not being out and being active is much being indoors so it putting in those hours and you not try and hit on this in the past but what was your interpretation of maybe this is an institution of health that I'm in but make no mistake it's an institution and it absolutely needs an industry what did you think about the hospital industry where you're supposed to be delivering health and then maybe some of the execution of some of that as it is rolled out right and that's where you have met so morally I saw some things but didn't sit well with me being in that industry right. I saw that that said you have the patient the becomes accomplished someone that's there in the middle right and you have for me in a lot of cases you would have the insurance companies now and the doctors going back and forth and becomes more like an a number you know the patient becomes maybe a number of verses like eyelets really care what's going on here rather than like walking into be like okay who's is insurance what you know what the insurance here you know in and so that for me is like it was just a is one of the minor things but as one things got my attention you know that like it's it's not where the healthcare system is for me is like need to be more focused on you know the patient and patient health patient well-being rather than be no worrying about you know needed the money parts in the insurances and I know that out that all plays a very important role in it all for sure but I just cannot seem like there the patient was kinda being put to the wayside in this I now and so that was for me one of the indicators like I don't know if I'd want to stay in this enough for I make a career lie I know that the three or those that you referenced Rivero McKenna and have Blahnik they all were incredible patient advocate I will as I say so is the hard part I see nothing and struggle with it to it's like how can I deliver the service in can you know this a lot of times it's not even can I do this without insurance it's driving have a place to allow this you try to do a charity case here recently in almost got blocked when you're trying to give up your time and that kind of stuff gets in the way when you're like look I'm just trying to provide a service who needs it we get others who are able to basically start so yeah unfortunately it's super complex absolutely we have developed a system that is an organism that feeds on itself we have developed a system where will I crisscross or talk about all the time yeah we are trying to fix the end organ thing and trying to and then people have figured out how to make a profit on it right I remember listening to Peter Addie a talk one time or he's use a party thoracic surgeon I think is he really felt like he was at the bottom of the hospital and people were lobbing eggs yes try to catch the eggs like when we quit throwing the eggs out the window that and that's kinda what you're getting at where your mind I can see that you are very in tune to your feelings nature and everything and that's really cool that you took a step back and with wait a minute this is not for me write Dr. Bill to solve it so sure not to go to hospital ministration politics and arrive the eye that I was working I was editing blogs for a guy who's really in the sustainability name Rob Greenfield and when I was working with him I was like man how to weep back I would love to try to take on the medical industry and just the waste that they produce the thing I so I'd like to have the ambition again if I like how can this happen but then again you know it's such a he there so many things are going on with it but the act is something that I can't solve I took a step back and said well this I would I would love I know it's going on but I'm texted back and what's best for me and so that led to me I did take one last hurrah as a travel surgical tech when travel took some contracts the United States Tennessee, where my mind was on that oh it's not just wise Kelly not just a problem yeah yeah was there it was there a strong proverbial straw that, I was like you know what this is this the part that is nonnegotiable for me or was it just counted everything together kind of at EL it is all Elkanah came together and it was where I was in life any of these can I felt like a time to move on the I love the people I work with and and you know I was I enjoyed my time doing that but at same time as I was I was ready for more I want to be fulfilled I wanted to I need a challenge I need a challenge titled how old is your son of the sun so I have a daughter daughter she's eight right now so back didn't see you whenever I stopped all this you know she was 56 yeah yeah yeah really and so I imagine that you you left there for much more lucrative investment banking type thing yes so quite the opposite so what I did is I think a little money I did have and I purchased a school bus and herded into the camper and then spent the rest of money on Christmas gifts for the family that year in then yeah converted a school bus into a camper and went roaming around in the mountains of New Mexico and Libya Colorado and no plan really other than I wanted to get in the travel like I'm like now the time to do it I want to figure out a way to make a living no traveling so what do I do I get the school bus converted numb site I start inviting people on these adventures of the mountain second as I get a venture you know pay for gas give me a lecture and not show you great time have connections in New Mexico and Colorado and you know various other places in Texas so that was my first kind of entrepreneurial thing how people find social media yet is utilizing social media I started I became part of this group called superhero Academy I can find them superhero Kennedy.net or anywhere online and get a really good thing going on start learning about social entre nous or ship just how to utilize Facebook and Instagram and YouTube to make a living right to to purchase about their the brand yourself right so this is back in 2015 or so that I started the 2015 716 anyway so far I started that's how I started back the tyro knew like that's that's where I was posting this with my close community friends and family on Facebook and now this were my first few customers came from and went from there to a long bus or short bios have a short bus it was like when it was an old law wasn't it was a 1998 Thomas and it was more the shorter versions wasn't a long one but it was necessary like a short bus I was like one of those admitted weird big block at tween area as I get a big and blocky and now but it only had like 67,000 miles and was a diesel when I bought it from a kid that was moving down to Texas A&M and had it for his buddies to go fishing in and paid 4300 bucks for it and I was like this is a little nugget of gold right here that she sounds pretty awesome like it like your first year just ended up being like serial murderers are you by your Jason is a guy yeah my trash back to him he probably would've lightened up on my trip that we had a good time and that's what it was about that was about getting out and finding yourself in exploring and being out nature and also just the travel experience in the cognitive effects it does have on the mind and just in and just how healthy it I think it I think a lot of our health starts at are in our minor thought process in her brain so that's what I wanted to show people hate get out do what you love but also here's a healthy way to do it by getting outside and pushing yourself challenge yourself let's go skiing let's go snowboarding go kayaking you know let's go hiking up in the mountains so that's really cool that's actually the stuff you do it was a bit was like an adventure bus it was an adventure bus yeah and that's what it was absolutely Jerry problems with that that 98 diesel in the in the cold ever fired up yeah I mean to mean no serious problems there was a couple mornings are there were a couple mornings where if you select slow start but even use a fire right up and this thing was a beast it was it just ran and ran and ran and I think part of it is because it had low mileage and he was just kinda getting broken and you know like a decent run forever and ever and it is getting broken in but now it fired right up in the mountains that is the exact opposite of the job that you are doing is a surgical tech maps act opposite yeah that is a bit just real quick before we have 30 seconds to break but okay did you feel that the moment you began to engage with people on a personal level that suddenly now you're starting to feel an elevated mood versus always seen patients are asleep absolutely absolutely that was my favorite part of actually being in the surgery is like you know commuting with those patients before they were when it went under and in yes when I moved into and started talking people one on one that was where I really start to thrive wherever this Latin is half-hour ending in that joint to begin for the next hour but will be back in just a moment and that's not where his story stop seated at this is the only 24 hour take anywhere platforms dedicated to food and fun query spoony this our Townhall.com intelligence committee issuing subpoenas for former national security advisor Michael Flynn and former Trump Deputy campaign manager Rick Yates is part of the committee's ongoing investigation of counterintelligence issues raised by the molar report Committee Chairman Adam Schiff says the two have refused to cooperate fully the subpoenas demand that the to submit documents by June 26 and appear for testimony on July 10 both Liam and Gates are cooperating with prosecutors in ongoing investigations both have entered guilty pleas to various crimes connected to the Russian interference in the 2016 elections but have yet to be sentenced Capitol Hill correspondent Wally Hines amid heightened tension in the Persian Gulf region two oil tankers have apparently been attacks in the Gulf of Oman the two vessels reportedly hate sends out signals and their crews were evacuated who might have carried out these attacks and how is not yet clear this is happened in shipping lanes that carry a significant amount of the world's oil supplies and at a time of high tension in the region the US recently tightened its sanctions on Iran and reinforced its ministry in the golf the BBC's Alan Johnson Pres. Trump says there is no harm in lessening that's what he tells ABC's George Stephanopoulos who asked the president whether he would accept campaign dirt against a political rival, foreign sources somebody call from a country Norway we have information on your I think I want to hear Mr. Trump insisted simply listening to the information would not constitute outside interference in a US election Dr. higher on Wall Street this our Dow is up about 94 points NASDAQ ahead 51 S&P 500 index up 12 points more on the stories@townhall.com are you tired of high cable TV rates sign up for dish today and get a $500 bonus offer while supplies last loss lock in your price for two years guaranteed call American dish your dish authorized retailer now 800-570-6630 800-570-6630 that's 800-570-6630 offers required critical negation 20 from early termination supply call for details if you are trying to quit drinking or doing too many drugs listen to me you don't know me and will never meet I had a problem 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our number two episode 14 catching project check your ego at the door nothing is off the table where joining Dave I Cooper read digital and social entrepreneur and of course a maps advocate and a volunteer position to project we will get to that in just a moment but let's touch base again in case you've forgotten love my tummy.com/spoony get your discount on our Tron teal today in the big challenge for everyone everybody to commit buy a bottle for a friend or family member use that code Cusick is a winner there and don't forget if you really want to you really want to win subscribe and share the gut check project go to catch a project on YouTube to get a project to channel or search for catching project on iTunes subscribe then all you have to do is go to KB MD health.com or get check project.com connect with us let us know that you did it to be entered and draw at least five winners in July 5 words literally going to get the signature protection package which is trying to heal and KB MD CBD one month supply no cost to you enter as many times as you want the course will to see what happened to me of times you can subscribe so I but will will go that route if you're new to get your project we are hosted on the spoony network and there's an amazing array of shows that they are that dad Dr. Brown and I both have trying to take in as many episodes as we can everything from family meal was chef Mark Conway to know but it's too big to tryst with 20 that's with Alisa Shakespeare in a course the great Jeff Patrick Mosher's on this channel also so tune into this bony network if you ever want to learn a little bit about food it's not just gut check project on here talking about new innovations in health and new approaches it is also a lot about food and food science and improving the way to cheat would just try to make this is about make everybody better and were listening to Cooper talk about some really cool brave changes in his life he saw that his health was heading in the wrong direction pivoted and got that bus/camper started doing things so you start to discover nature and thinks a lot of things that I like to do sometimes with Eric all acts I'll ask him philosophy quotes if he can remember the philosopher who said it so here is the philosophical quote of the day reality is wrong dreams are for review rally is wrong dreams are for it that's that was what Tupac did Jesus talk was a philosopher man like EEA you know like say what you want about it but a lot of people love them but man is some content you just can't new to the game straight to the hip-hop repertoire not as nice Cooper welcome to the show the other episodes but yeah no you don't normally it said said little Wayne little Waylon today but I don't know I think is pushing the boundaries on so it's not it's not it's not silent geez and lasagna cheese lasagna is a boost as a whole website dedicated to little Wayne quotes posted in a wheelchair called a virgin mobile I have yours wrapped that truth that I just liked how what what points are you going to maps.org the new sailor cited writes music would you like to put all some of Everett is leading yeah you do it on the right some crazy. So hey we we left off last half-hour you are talking about that the bus you have any you have any experience in the busted may be didn't go exactly as planned yeah I had a couple know the one that sticks out the most though as we are in Taos New Mexico and it had been yet sounds what now love town elements my favorite so we were but we'd been there for about a week or so was with my brother and my friend Amy Shane we were descending at time of the mountain some other friends were over in Angelfire so we like minute but then down the mountains and it is time to go home and we came in on this like really sketchy like mountain trail it wears like I was I had been there several times and came in like the normal way but for whatever reason the GPS Lake was late go this direction and I like and save you yeah and I was like okay cool working to go this way in the back way in and so naturally like when we left like there was a hit there had been snow in and you know the temperatures drop to about to zero while we are there so we're heading out like go back that direction and see what happens and it was not a good choice we got up I was going uphill on these frozen Rosie on this is Charles all dirt you know this is just rocks and dirt and I might die and you and you a sketchy going up on Mike you know what I was gonna go with it and see what happens and no okay now we start sliding me know and I can't get it under control wind up I am trying to press the brakes at one point words, this incline gives airlines on this bus it and I don't even know honestly have no idea. It really cold yet you know we are just sliding and back back back back you know we cannot almost scan were going off of the mountain side a little bit was like a steep drop off but it would been something I could not of gotten out of so I tried to like steer it back in it just as I was sliding backwards or turn the wheel I turned the wheel and got it like just perpendicular with the road and try to pull out but even even turning in trying to get out of it is made the situation even more and I going into the bank of the road saying on the bus and everyone well after a lot of silence strays silence a lot of you like any nobody has a lot to home of the engine going and being out everyone just quiet like what like why did you take us this nightly understanding about adventure but I like this is not for us and he only is my brother is just back there shaking his head like I don't know how to get out of this is like I understand you got insured for the show exactly know this is go anyway so we go to the bank in the nose of the bus is stuck into the side of the road in the snow and all that so we had to get Dick to the city officials or the Rangers I think that the park ranger showed up in his big old snowplow monster truck looking thing comes out in the tie chain on and yank us out and get us going back the opposite direction back to the safe road is a trail used to make she made down yeah yeah they did they did because the rest of luckily I was like downhill so it is an easy cruise down but but that was a sketchy moment because like we are most went off the mountain backside and we crashed into the bank on the outside so so when you are following this snowcapped thing didn't have a bumper sticker that said if you can read this. It arises you know that I don't know if Manny was like I want to try to go at it that that's not I would not do I would only like Joe will like Mossad I totally admire you from doing that and I think that is what so cool you left this career you jumped in both feet and you start pushing your boundaries exactly inc

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#112 - Dr. Ken Brown: Polyphenols, Fasting Mimicking Diets, Time Restricted Eating, Circadian Rhythms, Polyphenols, Skipping Breakfast And Heart Attacks, Dirty Keto, Carnivore, Atrantil, And More!

fasting diets heart attacks microbiome carnivore circadian rhythm hippocampus mimicking time restricted eating ifp polyphenols ken brown skipping breakfast dirty keto atrantil

Play Episode Listen Later Jun 10, 2019 69:29 Transcription Available

Visit IFpodcast.com/episode112 for full show notes, links, references, and more! 01:05 - JOOVV RED LIGHT THERAPY DEVICES: Use The Link Joovv.com/IFPodcast With The Code IFPODCAST For A Free Gift! Just for our listeners, use the link lovemytummy.com/ifp with the code IFP, to get 10% off your purchase of Atrantil! 7:30 - Dr. Ken Brown's Background 9:30 - Study Shows Skipping Breakfast Increases Heart Attack Risk? 16:45 - How Does Circadian Rhythm Play A Part With IF? 21:40 - Time Restricted Eating, Circadian Rhythm, The Hippocampus, and Microbiome 23:40 - Polyphenols As Fasting Mimetics 24:20 - Intermittent Fasting For Cellular Health 26:50 - Fasting Synergy With Polyphenols And Exercise 27:30 - "Dirty Keto" 29:30 - Extended Fasts And The Fasting Mimicking Diet 33:50 - Hacking The FMD? 35:10 - Fasting For Ulcerative Colitis And Leaky Gut 36:30 - BONAFIDE BONE BROTH: Go To BonafideProvisions.com, Add Three Keto Broths To Your Order, And Use The Code IF3FREE To Get Them FREE! 38:00 - Water Fasting Vs. Prolon Experience 40:30 - Caloric Restriction Mimetics 46:10 - The Fantastic Benefits Of Fasting - Cancer Potential 49:20 - The Carnivore Diet, Plant Polyphenols, And The Gut Microbiome 59:40 - Atrantil Polyphenols For Exercise Performance And Recovery 1:03:05 - Atrantil: Who And Why To Take? 1:05:15 - Atrantil: When To Take? (While Fasting?) 1:06:45 - Use The Link lovemytummy.com/ifp With The Code IFP For 10% Off Atrantil! For information regarding your data privacy, visit acast.com/privacy

Leif Harrison, Dir. Bus. Development for Elixinol

Play Episode Listen Later Jun 6, 2019 117:30

Leif Harrison has entered the world of the Hemp business after a multi-varied work experience in both high-level corporate business and post US Navy career. Born in AZ, raised in OH, Leif was a scholarship competitive sailor for the US Naval Academy. He is a trained parachutist, and tells of his religious calling to embark upon a 40 day fast. Incredible show about resolve and calling, check it out!And now I thought from Geico motorcycle it took 15 minutes to take a spirit animal quiz online please be the cheetah please be the cheetah and learn your animal isn't the cheetah but before less appealing blog fish come on let insult to injury you could've use those 15 blood fish minutes to switch your motorcycle insurance to Geico Geico 15 minutes could save you 15% or more on motorcycle insurance hello listeners out there it's a gut check project here with your host Dr. Ken Brown I'm Eric Rager and a course I got check project you check your egos at the door and nothing's off the table this is episode number 13 Doug Brown with that number 13 I miss that music bandwidth we actually had to travel little bits we missed last week we did a rerun on that one but I love that music and get my little metal groove I'll never hit him like a word and have some fun today yeah you know it's it you remind me of that you say you miss at music the music that I remembered when I was younger on Thursdays was cost show but were not going to be putting anything anybody's drinks so just mean you great way to open the show will will be, oh boy you will about sweaters anymore is it stepping out about sweaters so let's let's touch on that last week we've been trying for two and half years to you to get to the Institute functional medicine shall and this year we got our first chance to be a part of it I would say it right being Trond Teal trying to and that we were joined by Mike Logsdon and I think the three of us unanimously decided that not only was a great exposure for trying to heal we connected with people that have been using arch on teal for a long time and on top of that I think that we found a lot of new fans who just basically wanted new explanation on how much until could fit into their practice they love the fact it was less expensive was all natural solution for bloating and a course in Canada we can say IBS and Joseph say afterwards a I BSA but not BSC and obviously is IDSA but it was what you think I thought that the exposure to that level of really involved in caring practitioner was cute well so we the I FM this was the international IFN meeting we been trying to get in there for a long time what I learned from that was holy cow there are a lot of very smart doctors who are now adopting this functional approach because the system that we have right now are we just treat diseases it's breaking the bank lately it is a broken system that needs to feed on itself so these are a group of doctors that have flown in from all over the world and there are trying to help people at the base level so that we don't have to get to a point where they're being prescribed opioids or whether being prescribed this were to do this thing and so have a booth there without trying to and then have all these doctors that already knew about us was such a cool experience speaking of all of those positions that were there think about some of the other people that were there talking about their new delivery systems or for instance Carolyn Krishnan and just so everyone knows we can do a quick reset writ right here if you don't mind last week we did have shell so because we were on the road we didn't have the ability to do remote show because we were doing a completely different set up that being said Ron Krishnan of mega spore or actually it's like bio lads the makers of the megastore is a fantastic probiotic and we ended up doing a recording which will be released later this month of thus interviewing with Charon those kinds of innovative minds that's what's all over the IFN it's new ways to deliver health and wellness in a savings to the patient using in most cases natural approaches and they work they have science that backs it up is really super exciting that was so cool so first of all thank you get on yeah for taking us to have future results with amazing Peruvian Asian fusion restaurant and we just had a blast we did and I love being around like-minded people and entrepreneur who's a scientist she's a microbiologist in his training when he came to the house we did the podcast he kicked some crazy knowledge absolutely phenomenal as to why you should be using a spore based probiotic and not a traditional probiotic based on plausible science replicated in the lab that is what is amazing she is all about will that makes sense let's test he is a researcher first entrepreneur second and that's kind of the model we have outrun to you is because really we've got some science to back it and that's why we developed it and that's why think were gonna be able to possibly work together to really help a lot of people using the combination of the two dad hates he says he's pretty amazing in the way that he talks about science it's like he's talking about a friend oh he's just I mean he describes the you have to listen to this episode because it's so into it that it's so cool but we come from bacteria make no mistake about it yet and we have lost sight of that and we have developed a world that kills what he calls the whole mobile which is a term of never heard is a real rain forest when you take out the canopy things die and we have systematically been destroying our own God given reason why were here which is our micro bio and were all about the microbe I'm also talking about polyphenols talk about probiotics protecting Mike by Marissa said he just came out I just saw that yesterday where they were looking at how the micro biome affects aging if you have a healthy micro biome is an anti-aging situation then and it set in really when you start digging into the science that your Acheron and now is butchering his name so Chiron uses to back up where why spore-based probiotics are not only more efficacious but actually more natural and then you begin to look at how the micro biome itself benefits from having a spore base probiotic make its way to the: it's it really the mysteries no longer mystery it makes sense on why you need to care for that for your body and your you're basically a vehicle for bacteria and if you're keeping them healthy and happy you can be healthy and happy it's the signals we talked about what we've always talked on the bottom of this we talked a few episodes ago were in TCU they did the study with injected people would like the polysaccharides and they show that the new information created impulse problems the lead to anxiety all kinds of stuff please brought up LPS that's exactly what he talked about was a better marker remember that instead of just using C-reactive protein and other markers to find true long long-term information in order to find out if you could heal the gut LPS was a better marker and you could speak to distant is that something that current practitioners through traditional medicine are using no traditional medicine does not look at LPS I do have a science article today were really touching a little bit Because when we talked about the leaky got leading to leaky brain right well I got really cool article just published this month 2000 19 June 2019 will real look at how CBD and a cannabinoid like Endo cannabinoid called PEA actually some really cool science on that and that's what we always come back to bridging the gap or to trying take some science and bring it over here John was talking about that the whole time because this doesn't make sense why people are doing this with probiotics when we should be doing this because this makes a lot more sense we want to ruin that episode because I think it is one of the coolest funny nerdy episodes were we get way into it because just like you talk about he talks about the spores like there is little baby that he loves those things yet he does and you're right we don't want it we don't want to spoil that episode because we will release it here in a couple weeks however today on today's episode we have an incredible guest who's got a great journey and his story on how he got to where he is today that's Lafe Harrison now currently he is an executive for director of operations for licks and all and we know quite well from that but he's got so much more depth than just somebody who who lucked into being in a frontier industry in fact one of the coolest things about Lafe and the fact that he's in the hemp industry is this is a man who has a military service in the Naval Academy was in Annapolis he was trained by the Army on becoming a parachutist he's got tactical training not only in the Navy but as a civilian he worked at Boeing am I gonna ruin his whole biography will let him do it but the man has got lots of exposure from the military from a large corporate structure and now working in literally the wild West of a very legitimate industry which needs legitimacy absolutely and that's one of the reasons why we have teamed up with election all because I really think that they are just a step above everybody else we've had Joy Beckerman on that they brought on and she is a procedure and policy expert Christmas song with the marketing he's been involved in that a listen to those two episodes were to have Dr. Paul Blair onward and talk about the science PTSD and all that what we have with Lafe is this business background really smart guy coming from incredible background to say no you need to legitimize this because this is real it's not going away and people need this we talk about healthcare dollars we talk about functional medicine CBD is not going away and we just need legitimate companies producing great products without question so stay tuned life will join us in the next half hour and well let's see here real quick paying the bills go to love my tummy.com if you weren't at the IFN conference and you would like to learn a little bit more about our 2011 my tummy.com/spoony use code spinning say some money and you'll see everything that Mike Ken and I talked about bollard in San Antonio that I have him and we will definitely be back next year that was a fantastic get to that was really cool but seriously I want everyone to commit to this please go to that website support everyone because the supports spooning the supports functional medicine supports upfront Hill which were also doing research were teaming up with the board meeting all kinds of stuff so love my Tommy.com/spoony SP 00 NY last thing forgetting to Dr. King's corners going to be we keep getting responses of people who have now decided to subscribe to iTunes I do want to remind everyone you can also subscribe to gut check project on YouTube where you can enter again and of course if you subscribe screenshot that you have subscribed go ahead and leave its review and in July we will be awarding at least five winners a free month supply of arch on teal as well as KB MD CBD of your choosing either natural or Senate flavor and death funny story about that real quick before I finish out how you can enter and that is we have a friend whose son is he was a bull rider suffered a brain injury and has seizures now so this is completely anecdotal I don't want to make a huge claim here but however is been struggling on what's the correct diet recipe for myself not have these issues has a neurologist that he sees at Wichita Falls and he recently began using KB MD CBD just last night that mom that dad that young man let me know that he doesn't go anywhere without his KB MD CBD now and he doesn't have nearly the exacerbations of his seizure activity absolute love that loving source like that these are real this is not a subjective oh I filled out better this is not a placebo effect is somebody that has objective data showing that they have improvement in something not a disease claim ever get so scared about saying that but what we did learn from note get on is that you can say what it helps but not the disease so if we can decrease neural impulsivity which leads to a seizure sure that's that's really the marker that we can do and that's kind of science we need to get out there absolutely so just to continue if you want to win your own free trying to link a B&B CVD subscribe screenshot share write review send a notification to us that you've done that@kbmdhealth.com or gut check project.com just go under connect you'll see the drop-down menu can let us know that you have subscribed and you will be entered and then you can be a winner that's it everyone wins that's everyone wins so Dr. Brown going on not much so you know we talked about the IFN this really cool I have not been sick to years and years and years and I finally got like my first cold/I don't know what it was bad in years and it's fun so I did not go during the proliferative stage of the virus I made sure that I secluded myself forcing happened on a Friday and I could, hide and let that go but then come to develop the bronchitis afterwards and had to go to a show right when you talk so Nate spurred recipe that we were in beautiful San Antonio fry FM over near it was held at the JW Marriott great little air B&B we stayed out that was cool like right off property so that was me that was nice you can schedule the wrong day so little funny story to the sum of what you tell it because I'm a little embarrassed so I'll throw it back to you you can describe what happened so basically can you tell me that Eric I'll meet you down there I'm flying to your driving or taking equipment down and I did it when checked in and then I went to the location where the home was forced to stay and I rang the proprietor and just as you said I should she's incredibly friendly and she said hey how you doing as I can find to this is Eric reinstate your house he said yeah yeah can't wait see you tomorrow and I I will that's cool because I'm here today and she couldn't of been more accommodating she laughed she got everything ready within an hour home was beautiful so we had that we had a great stay but she was able scramble around everything up and running if you've never done a home share things like Uber I mean the RBL air B&B are both super easy to use and huge house very comfortable and not really expensive for is using for to consider the Princeton hotels under them no because we were correct eventually got you a few people be you and Mike it was pretty funny because that's what happens when you've got two people that are busy doing a bunch of other things and just sort of all you have to put the place yes okay doubled up on you move on and so it probably would be better if we just had somebody to be handling that kind of stuff for so yeah now it's okay if the Internet well out turned out perfect and so we went to beautiful San Antonio like I said Johnson was also a great dinner we had a wonderful time that's a joy to my training so I'm I'm very fond of Sen. that's where I met my wife that's all that stuff so going doctors always find a lot of people there but that was a great great conference I was awesome while I was there quick update on the family Carla actually had a tennis tournament and she killed it in Dallas in the Dallas area she won the whole thing so she started to really hit stride right now really proud of her and you know she's realizing that there's a lot of both physical skill but you in tennis you really have to put the mental with it because Rother alone and she's really hit your group right now and band were to be having some national tournaments coming up with both kids are now playing on the national level so I'm very proud of Carl she did awesome Lucas appears we go through a growth spurt because he did actually nothing just slept the night I don't blame you Lucas and good Alcala network so and then of course myself to him with cold and though you know Lloyd is basically has to make sure the kids get started so how about you guys not everything on our home front is great breeze business sat with her wellness Center continues to grow and Doug Gage had day 17 had his wisdom teeth taken out I guess it was that you have days ago and he's recovering but he's doing well maybe we expect good things I think it will be back to his normal self by about a day or two and then nab Mac we had at several so yard turn in early summer that need new sod around town around Decatur so Mac went out after basketball practice on its was Monday and Tuesday and basically he's visit by he's in a new entrepreneur is nice walking home with 200 bucks a day throwing sod saw death that is not easy I did that when I got my first home in San Antonio so he's pretty pumped about then the little change in his pocket and dad not enough time to spend it's that's the best way to do it and for 15-year-old it said it's not too bad there that's awesome that's awesome now that's it that lets you like the removing all Midsummer that's cool we quick shout out to Melanie Avalon and Jen Stevens because I did the intermittent fasting podcast again love going on their show had a great time talk about all kinds of stuff I want things that we did hit on which I actually had a little research was the carnivore diet told him about it well recordable diet it's basically meet nominate me all right and while doing some homework on that you actually pointed to Jordan Peterson out to me right you how did you find Jordan Peterson and the work he was doing originally actually it is this attribute to gauge gauge is a big he just spends his time reading about different things all the time and he finds Jordan Peterson to be somewhat interesting just as a personality himself just so happens that Jordan and his daughter I believe suffer from his daughter deftly suffers from some autoimmune issues that they should be the most outspoken person with this correct Michaela right at sadly that's her name and so she and Jordan both had at least some type of autoimmune issues they both reset decided to go and try to carnivore dad had been reading about it and according to them they don't have those issues anymore and I think he's 18 months into it or something like that it's around that time on I can't member exactly but I have heard his interview on Joe Rogan and a few other different podcasts where but Rogan is 16 at the most disease has the longest format and it's really interesting to hear someone make that transition I love vegetables I love fruit so I don't know if the carnivore diet is for me did you see the Joe Rogan Sean Baker one the orthopedic surgeon that Stu the carnivore died as well now I know he's quite outspoken also not really on Instagram much but I've seen that he's pretty prolific and basically showing that he likes meat he likes meet similar thing where he went his orthopedic surgeon really smart guy is doing strictly meat is eaten quite a bit of meat so I have my first patient we had a long talk and we tried a bunch of different diets still struggle with some stuff and so I put them on the cardboard I've lost two weeks he feels good really yet so my knee-jerk reaction would be no way like everybody else like every other diet that's out there is a traditional doctor you look at this and you go want what Haley oh no go oh well that's kind of interesting sure OT don't know now Tito I tried you know I'm mostly pale Leo tried Tito I'd I it's difficult for me to say on what I do and we talk about this on the podcast so that comes out next Monday I believe all IFP yeah yeah intermittent fasting contest that she generally set next Monday which are all this but the problem is that a lot of people do like I do his dirty Quito you think your keto in the new country and ruin everything and I cannot screw your base are screwed some things up doing that so we look these different diets will the initial reaction is oh the carnivore diet that's crazy needs bad apples meet your: the John Wayne died with 20 pounds beautiful whatever clearly untrue and there are certain primal lineage people that really survive purely on meet during certain times of the Inuit Eskimos for instance trying to not eating vegetables now it's just strictly meat and then Sean Baker had some examples of some tribes in Africa that really only have meat and they are extremely healthy so I'm looking more into it not succumb only wants to talk about it so we got weird into that little bit that's first time I love going on podcast like that reps do little homework I like to listing every single week we trying to little homework we try and bring everybody up to speed and supercharge a little bit better at something and that's just another example looking into it I got my first patient experience with let's see what happens if you try the carnivore diet out there in your listeners GCP or you know someone has to choose an email I'm really curious to see what it's like in and what that transition is like and how do you feel how long did you do it what is it like it when we talked at Quito diet and doing dirty Quito I can certainly relate and I didn't realize I was relating in the same way out after I come avoiding carbs and avoiding sugars but something that I wasn't taken into account was was offsetting some of that by consuming probably more protein and a should have and you could probably speak this if you over consume the protein in terms the protein ratio to the fat body can actually just go through gluconeogenesis and basically use the protein turning circle and glucose he can for yourself out of Quito itself right yet it sounds sounds counterintuitive but Dr. Sean Baker extra possible disease is a power lifter hold couple records at his age group and he got arguments with other doctors were they said no you and enough glycogen in the muscle to do this with the fact you write on the protein the amino acids and then you for glycogen in the muscles that's fuel so people do Quito but they take to too much protein in and then you actually stored glycogen in your liver and your muscles and then when you work in fact you when you and I were fasting we did a little experiment with you where we were actually working in between patient oh yeah and we did the we have a keno mojo we we checked your ketones right Cheetos were up blood glucose was rewriting yet again 958 some around there and I'm okay let's try something once you do a bunch of squats that and what happened I think to check the glucose again was it 10 minutes later and I was at 76 to correct yet you go to slop in your teachers with relevant Burly ketones is fuel and immobilize some of the glycogen right muscle and so a lot of this physiology takes place and people don't realize that that's actually going on I did remaining in technical ketosis cadets .5 I believe on the Quito mojo hundred percent and so one of the things is to direct you just burn some key tones or did you mobilize like that I think will build both probably length and selection of stuff goes on the interesting thing to have motivated by intermittent fasting just the idea of it and you know this most days that only consume bacon and eggs for breakfast and so I typically stay in moderate ketosis in the morning until we finally get to lunch past the first half-hour was really fast holy cow I got so much more stuff to talk about placing a hopping but we didn't get to the to the study and and I run it by him and see what he thinks and I trust some of the new doing that but anything to add before we take this break I just want everybody to take this break and go to love my tummy.com/booty yeah yeah he should totally do that because it's the summer everybody wins there nothing out of some orders I will be back with Lafe Harrison here in just a moment say to get a project episode 13 Dr. Kim Brown here a host of check project with my cohost Eric Rieger Eric Regency and mojo guys over there and overhears Billy talk about our 20 over bloating I've seen in my practice that I'm trying to is a whole lot more than just a floating product yes it does a whole lot more than just exploding because the polyphenols that you find to and trying to get your exactly right the polyphenols are those molecules that we find in the Mediterranean diet it makes vegetables and fruit very colorful what are some of the things these polyphenols do Eric these polyphenols can actually stop in formation help you have more energy thinking have you antiaging and polyphenols are great athletes it sounds like it's your health: more people than just loading tell me how everybody should be taking out front if you want to go so 2002 capsules three times a day basically with if you aren't bloated just want that polyphenol intake every day to three classes a day will work for you go to love atomic.com/now you can fly anywhere in the world and pay discount prices on your airline tickets flight today to London Paris Madrid or anywhere else you want to go and pay a lot less guarantee quality international travel department right now low-cost airlines 800-452-1075 800-452-1075 that's 800-452-1075 never forgotten apparel is more than just a premium women's and men's clothing line it's a movement to remind us to where American-made and serve those who serve us our heroes never forgotten apparel gives 20% of their total sales to nonprofits that support homeless veterans and off-duty firefighters and 50% to individual veterans and firefighters in need nationwide checkout never forgotten apparel.com use promo code Matt and ATT and get 15% off your purchase all right but I for the second half hour it's getting project episode number 13 and we were talking as we close at the first half-hour about fasting and then I had asked Lafe don't say anymore because he chimed in and said I tried some of that fasting and I was going to think how long did you do it was like for five days like I dig that was really hard and he said no I did one that was how long 40 days and 40 nights that is was it is at the Daniel fast which was no that was just the irresistible call by God the fast route yeah so I just did some quick Internet research on like how to even attempt it and I settled on it was all water with a little bit of organic fruit juice in the morning in a little bit of organic veggie juice at night and I just ran without the hallway 40 days Yep that's the longest everybody doing it… Looking back on that this probably maybe four years ago literally not possible without God really I don't think I don't think a human being can just sit down and knock it out of the room while did you have a regimen of prayer that you are doing with those yes Ramadan the way that the that that is done yes I think it was probably to three times a day I had some note cards of prayer said it written down in advance and I just work through those with with issues I am my family were dealing with at the time we just work through that the whole time that's amazing there is when you look at fasting it's in every single religion really if you look at it oh yeah but in the only person I can remember this even come close to as long as life is that Rita Marie Scott oh that's right she went to and for the almost the same bid the same motivation she went and she went to a rosary uncle resort but is basically a place that they facilitate people that are going to do long term fast and they give them coaching they give them support they make certain that they don't have to move too much while they do it and make sure they have water that are hydrated but she member she said she did four weeks five weeks something like that did you have a die off. Her some. We went through like a keto Fluor that stuff the people to also I don't have any terms for it but you go through multiple stages during the whole process so my experience was probably about every 45 days you would switch from one aspect of it to an entirely new one and so it started out with incredible headaches and then those past and then this is my understanding I don't know if it's valid or not but it appears that may be there are a bunch heavy metal stored up in your body and that in the course of an extreme fast they are there being released and hopefully flushed out but apparently they tend to then collect in the larger muscle groups so you go through things like extreme thigh pain extreme back pain that type of thing and that's the only correlation I can make the why you get those kinds of pains but then again over the weeks of the fast they tend to be the focus and then they tend to move on from that you really selling this like I said it's not something that can be done on your own in my opinion so this is yeah holy cow identified a fast you get a water fast days I've done the prolonged fasting mimicking diet I've done fasting in my opinion is the greatest life hack you can do that what you did is like Navy seal stuff that is that it's tough it's my opinion it's God inspired and God supported so I don't think it can be done on your own and for the for the scripturally sound people out there I'm well aware that the Bible does speaks to this is not something you brag about I only share it because that was just a process I went through and and maybe somebody else can relate to that no is an incredible journey having a need and I don't think you're bragging all the interest it's an experience for so yeah know you're being very honest headaches yeah muscle aches half can only do it if I focus on prayer now that's I mean I think that that is there's a lot of people that need to reset and I I do the fast I fast for the five days usually around trying to do it four times a year and I find a lot of habits that I've developed that I go oh my gosh that's more of a habitual thing of having that snack or having a glass of wine at night or whatever when you start paying attention to it one surprise at the end I did need to come off it mean when I finally hit the goal I I could've kept going but I stopped but I wasn't expecting a part while it is that is that is very impressive and you said a word I like is reset so it sounds to me like life you you are inspired to do it and you had your own motivations one of them that you didn't specifically mention but of course the body being a temple it would only make sense what type of away from the spiritual benefits what type of of the body the improvements did you notice at the conclusion of the fast did you feel healthier did you sleep better did you find maybe even during the faster began to just have better periods of rest and in clarity as countries I don't know that I can speak to any of those specifically know what little reading I did on it leading up to it and then try to kind of understanding it after all all that happened was it you know if if losing weight is a goal of your fast then I'm under the impression that you really don't want to be in caloric deficit more than about 300 cal per day when you're doing an and at that level you tend to compensate for that deficit your body tends to burn way more fat than switch to muscle for calories when you do an extreme one that sort of 9010 ratio becomes more like 50-50 and so you you take hits across the board so it it literally came out to I think I was 39 pounds lighter after 40 days 39 pounds right but a lot I lost a lot of muscle mass in the process sure yeah I'm it's a sacrifice though for you for going for going through it to me nothing like that comes easy but I do think that there's a spiritual reset there's a family interaction reset this did you do with would with your wife was as you will know I I told her in advance and then we as I just I told her it just kept feeling this Paul and this not preoccupation with it but it just wouldn't set aside and then I I targeted the date for the future it started but I was just like I think I'm just going start now so I just wonder because this would be all you know I do know what was common and that would affect you know the family for a good six or seven weeks but I basically just started about a week or two after having it come top of mind and just did it that's impressive because limits are what I've had. During those five day fast each one had different issues but it I want to I wanted to date three you like to get them done you know I want to know this is I am hungry definitely did you go through so both Eric and I experienced there is a hormone called a Rex and that when you get to a certain point your body is telling you to get out there and go do something did you have a surge of energy at some point day for day five of the first know but I appreciate the people would do shorter fasts go through experiences like that so I think mentally I was in this for the long run but to the best that I could be so I wasn't thinking a bit in short chunks plus I was dealing with the fact that sort of various kinds of pain were coming and going up that would really absorb a lot of the moment but I do know that people do three day five day type runs it's almost F it's almost like a runner's euphoria but there's there's there are things that can kick in during that time's up that can make a pretty special and it's hard to access those other ways is not passing because mentally your body your body knew that it had to do this is the reason why the sexy chicks and it's it's it's an evolutionary thing where if you're if you're part of a tribe and you need your get food you haven't had food by day three or four you get this surge of energy and we all day I woke up at 1 AM and started cleaning the closet and it makes sense because this hormone kicks in as it says look you get you need to get food you need to go get a surge of energy when you get beyond that when you get into a longer fast that ends and then you're actually in the starvation mode you actually went to a starvation point yeah what's also interesting is you think about people lost at sea all kinds of situations you know civil unrest something where one food and water become an issue the really do seem to be some hard stops and hard stops tend to be like three days max without water or your you're in serious trouble but you could go 30 days without food and so I don't know I'm sure most people are prepared to try to do that but it seems like physiologically you could do that if you had to while that's just impressive but super impressive and it states and ended not so much the faster the duration it's the commitment did that life was able to put himself into seems aware of your background which is really cool and very clearly or very mentally strong person but you don't own it you say no I can only have done it with prayer and through God yet it was a it was a irresistible Paul was never something I thought about it just happened in that about two weeks later decided to just go for Noah to be more like you from now on I must start with this also to stand up for second look at as an irresistible pull here is an irresistible pull into your quick picture taught that ritualized picture because I would be more like life well Amazon just launched a brand-new thing at the connection started yesterday called Stiles snap and you can look at here is a picture of late that I just took their and then Amazon will build your outfit for me it's called style snap somebody has to find out so I can get there you go Tommy Hilfiger sure I can get from Amazon so basically my wife's been trying this for seven years and was left except that I get some genital pants and I will look exactly like yourself it's called style steps interesting so Amazon has not been very good about breaking through the clothing market assault news article on it yesterday they're just about to walk around the city and be like that person looks cool take a picture and then just order the whole outfit to your house right there I don't know if that's cool or creepy as hell's creepy that mean it is cool as a Tinker that said I could see me at day seven looking just like that be like my muscles my head hurts screw the sun what if you take a picture of somebody who's really really stacked now it doesn't show shortages has a bunch of waits for you to order a treadmill or something like that awful mail through a blender and some protein, videos is very sweet lady might sit in while we will be attacked this week's research topic must do this I so ever so weak we always I was trying to pick up something that's relatively new that I find interesting and most of the time it gets really science you really geeky so I try to dumb it down but this is really cool because a few weeks ago we talked about leaky gut and a lot of my colleagues in the traditional medicine space they don't even acknowledge we can get them say that we can get exist they say that there's no intestinal permeability we really do know that there's a lot of evidence out that the article we describe that time was leaky gut leaky blood brain barrier right now we have some evidence that Alzheimer's and dementia can actually be caused by intestinal health so this article just came out it was published in the inflammatory bowel disease June 2019 very recent very recent and what they actually looked at these researchers some really cool stuff that comes out of the UK and they looked at its action one article including two different studies one an in vitro study which means they do things outside of the body in a lab then they use that knowledge to piggyback it on and in vivo study in the in vivo's when you look at humans and you look at certain and outcomes so this is really cool and what they looked at is that we all know that the tight junction in the intestines it's a selectively permeable barrier you have to be able to absorb and take in calories and you know enforcement, fasting a lot of people with a lot of intestinal disease were they fast you really don't want to because they're not actually absorbing all the food without you taking it right so in addition to CBD that we always talk about right there are other endo- cannabinoid light compounds in the definition of them and we talked about that like Bridges owns one of them right but another one is called PEA or Powell toy less than Nola mind and this is an atypical and a cannabinoid possession found in foods was found in soybeans some found in eggs in our body X produces it it increases your own endogenous and then my levels and it actually binds to certain receptors so little sightsee but it makes sense of this article looked at CBD and PEA PEA is one of those molecules that depending on how you want to use it but it is an entourage molecule so it actually works together with CBD in your own and a cannabinoid system so they have shown that PEA can buy to something called PE part alpha which is just a receptor similar to an end of cannabinoid receptor just keep that in mind. So this group had previously shown that inflammation actually causes an increase in the permeability of the intestine so these guys are on the forefront of leaky gut and have always been on the forefront of this they looked at how CBD in previous animal models could actually help this may publish this big meta-analysis looking at animals on how CBD and PEA can actually correct leaky gut based on this they went down this path and this is the study that they are she just published so when we had to don on the show he geek out like crazy and he deftly did this is my digging out because this justifies a lot of the stuff and why a lot of the reasons why all health begins and ends in the why will become sicker as a society I am working some of that crisscross article that you have it that you got from him and it makes total sense so the in vitro part of this is that they took intestinal tissue human intestinal tissue and they soaked it in these inflammatory cytokines so these are cytokines that your body produces when it's exposed to toxins specifically like TNF alpha interferon gamma and things like that they showed that this inflammation caused an increase in leaky gut and they looked at these very specific cell parameters were they could show oh look this size of molecule came through and they did it in a very elegant study so is this tend to be outside molecules penetrating or inside materials leaving so what they did is they soaked the tissue in these inflammatory cytokines and then they used immunofluorescence to show that it actually was going through from one side to the other so inside to well technically the inside of the lumen crossing the barrier into the inside of what ever that they had this case it was just another medium but it would normally be crossing into the lemon appropriate where your body would react to it so essentially what you're saying is the particles that shouldn't have been making its way to the bloodstream are now being sampled by the lecturer in this piece of fish priceless first time I've ever read an article recently looked at this and said leaky gut does exist when you cause inflammation this actually happens okay so then they added PEA okay the molecule that is cannabinoid -like receptor that is found in a full spectrum hemp product so it's going to be one of the entourage molecules that and they showed that the PEA markedly decreased the penetration of these modules I good so then I said okay will that's objectively try to cool so then they blocked the receptor the PEA binds to copy part alpha so they did that with another molecule the leaking us continued continued impressive so now we know so we sit there and we talked about where's the science in the CBD and cannabinoid industry there's people like this publishing this and nobody talk about this absolutely amazing because they said okay look it's Dr. then we blocked where it works and it happened again development I saw then they added CBD this also markedly improved the permeability stop the permeability then there able to bind the CD1 receptor and it happened again okay so they get a molecular model where they showed oh this is what is happening it actually prevents leaky gut this in my mind proves a subtle level that inflammatory markers alone can create intestinal permeability or leaky gut but now we have a mechanism but I can tell my patients like this is why I like to use these products and the symptoms that you have we now know that when somebody comes in and they got bloating and that hurt to get a bad diet a highly processed diet and they say things like I have brain fog I feel fatigued I've developed Hashimoto's I've got this we know that you've now open this gate in your body is reacting to the outside world specifically to be reacting to bacterial components to antigens things like that so many of these people this is how I got into talk about CBD the first W. Soucy in such incredible improvement sure I don't really know why you're getting better now we have a reason why don't you feel like at these levels of validation in terms of discovering what the NOAA I'm sorry but the mechanism of action is in part is is one of the key pieces that universally the hemp industry just needs for the validation and actually it's not even about the hemp industry that could be the diet industry could be anything where there is applicable beyond anecdotal improvement it's just how do I piece together the science to show that what were doing is going to actually work I think that we can do that with studies like that when you study like that were the plausibility of it makes sense and these guys clearly are deep into the weeds in this kind of stuff this is your passion and they've Artie done that analysis on on animal model so they Had a pretty good idea look we just did approve it on so so then I kicked up a notch in the same paper which is fastening which is basically two different study right and it is pretty fascinating then I decided okay this is cool know if you believe us let's see what we can do in humans so the same group took 30 individuals and gave them high dose aspirin aspirin in itself can actually create it's an inflammatory thing we know aspirin creates ulcers I'll see people commit with G.I. bleeds and know their own aspirin as per the some good things but also increases intestinal permeability okay so the way that they prove this is that they got people they gave an aspirin and then they did what's called a lactose mannitol test it's an interesting old test that mannitol is a very small molecule and it'll go through MB absorbed the depute out lactulose is a big molecule and technically you don't absorb it and you'll poop it up tonight if you have intestinal permeability that lactulose mannitol ratio comes closer so you start peeing some lactulose out night so they get aspirin until people start P lactulose so that was pretty impressive yeah want a good baseline for coming things down I think I followed that I like that they did references, funny they did reference other science articles as to why they use as principles other things in the reference a few trials in Europe were people try to give them straight micro polysaccharides which is bacteria and people and subjects of the so all of this is not an ideal test at the close of you gets up like this so what they determined that they had leaky gut and what they determined that they were peeing out this lactulose they randomly this was a randomized placebo-controlled trial gave them CBD PEA more placebo okay now they did give a pretty high dose of CBD at 6 mg and PEF 600 mg per day yes per day and admittedly said there was sort of rescaling given that docent sure happens they try to base it off some of the ratios that they soaked the tissue in in the first study but they admittedly say were just trying this to see what happened they didn't they did have a placebo-controlled though they did have a placebo correct so they were able to show that the addition of CBD and PEA dramatically reduce the lactulose mannitol ratio okay so in humans they showed that at least with this particular test leaky gut improved they took it one step further these guys are mean it's like it but I would publish the first part sure been eureka and they do this one and the lightweight I wait for it right let's take molecules which of the exact size of bacterial life policy okay without causing sepsis important so they found these text rents called FB for nifty 10 which II just I love science minds work were somebody just goes let's get the exact size because the size thing right and if it crosses then we know that they're going to react to the lie proposed record of the to react to the bacteria these happen to be very similar to the size of E. coli and I commend what sucker with the other one was basically very common G.I. pathogen okay that we would actually act both CBD and PEA reduced the FD four and FD 10 transfers well so people were paying that so they're using it like a lactulose mannitol test and why this is relevant is because this is the first time in humans that two compounds have a mechanism to repair mucosal induced wiki that's impressive and they believe it's through changes in the tight junction receptors and something called optimal Warren three in the ileum I'm not her that I've not heard of it either as it turns out aqua porn three is something that in Crohn's disease gets upregulated to try to absorb more water so you don't get dehydrated so insight it's a mechanism that the body knows that the got is inflamed and you want to absorb more water so you can survive longer as you can go three days without water or if you have too much diary of that old new depleted share of the 30 days with food so it's an incredible mechanism that you can't beat mother nature yet it you you give it you give what the body needs it's going to do this so what they theorize that this is why it may be really useful inflammatory goddesses so in my space this is an incredible find where we've got did I get a lot of Crohn's and colitis have got a lot of the people with that I can at least look at them and say look I think that this might help because of this mechanism when you look at the research with mega spore biotic disease claim you're talking about mechanisms the mechanism makes sense and many of my colleagues on and believing that God so it's very hard to actually talk about hey I want to tell you about a disease process and then I will tell you how this molecule that you probably don't know anything about is you help and this is what were to get into the next half hour you know that the whole process of how you sit there and educate and where people, and that's what Lacey did to get a great incredible background but how do you educate someone on a benefit when they don't even know that the disease exists that's out white noise that we are talking about so well they forget to go through your your history and how you got to where you are but just we got just a couple of minutes what do you think since you are a director of business and the hemp industry when you hear new levels of validation for the application of hemp products and it's not it's not just subjective this is object of data what does that do to embolden the effort of education in and around CPD yeah I think two things come to mind one is thirst just a vacuum waiting to be filled bigger than we can imagine for science backed argument for what's going on that many many people can just anecdotally express but don't know what type of context or framework to put it in in the number two it's communication there are so many people waking up to what this seems to be and in doing so few sources to go to and also buyers in the CBD market needing a eight 1/2 a a simple message that resonates that speaks truth above all the noise in the market that is confusing it and probably in it in itself based on a lot of nonsense it's it's difficult to explain but it's just stressing that everybody coming in and taking a look needs to be brought in in in a way that that is anchored to truth to the best of our ability so that they can make the best decisions for themselves and I think that so what we I am a graduate student that helps us and she send me articles like this weekly she's like talk about this on your show this is really cool and this is a thick thick thick article so every time I talk to people my colleagues to traditional MDs go there's no science behind it like alone on yeah I got thousands of articles looking at the site you just haven't taken the time to do. Not a drug rep show up and go here's the detail piece we have been Pavlovian training that we should look at anything unless you have lunch in your that is that is the truth so that is going around up this half-hour going to be back here in just a moment but looking to bring back some context behind Lake Paris and see all in just a couple minutes this is the only 24 hour take anywhere platforms dedicated to food and fun queer spoony writing this hour from Townhall.com I'm Wally Hines marking the 75th anniversary of D-Day by honoring it survivors and the fallen June 6, 1944 operation overlord that massive Allied land and sea invasion of the French coast that began Nazi Germany's downfall help and World War II a year later to the Americans that fought there you are among the very greatest Americans who will ever live speaking your Omaha beach the president called them the pride of the nation French leader Emmanuel LeCrone said his nation thanks them and the other Allied troops who broke Hitler's hold on France we know what we owe do you vent the rents all freedom I'm solder man God before heading to Normandy the president telling reporters in Ireland he's not worried about threats to block his plans to impose tariffs on Mexico felt Mexico go on and I'm very happy with it and a lot of people have no idea what no no I ahead with those tariffs on Monday and less talks in Washington between the US and Mexico aimed at curbing illegal immigration bear some fruit a power outage at LAX last night scrambling check ins enforcing dozens of flight delays diversions or cancellations Katie bellum spoke with K NBC-TV right now all of the rest the lights are out and official say it second power bump because the airport go dark about 6 PM local Amazon says it's getting close to starting drone deliveries of packages in the coming months and promises some deliveries in 30 minutes or less news and analysis@townhall.com never forgotten apparel is more than just a premium women's and men's clothing line it's a movement to remind us to where American-made and serve those who serve us our heroes never forgotten apparel gives 20% of their total sales to nonprofits that support homeless veterans and off-duty firefighters and 50% to individual veterans and firefighters in need nationwide checkout never forgotten apparel.com use promo code Matt and ATT and get 15% off your purchase is the expenses through our yellow pills to charge your sex life are you thinking about what we can promise you the same results from three if you are paying $20 a pair for the underpants you're getting taken to the cleaners deliver the same results for less than three dollars and $16 account for the same results right now, stored at 44 blue or yellow pills for 23 discrete shipping you can save more than $100 our pharmacy prices right now and get your 44 pounds over $700 and qualify for free shipping over pain, right now 800-218-6473 800-218-6473 800-218-6473 that's 800-218-6473 Dr. Kim Brown here a host of project with my cohost Eric Rieger I've seen in my practice that outrun to the whole lot more than just the bloating product yes it is a whole lot more than just exploding because the polyphenols if you find in all 20 waters of the things these polyphenols do Eric these polyphenols help you have more energy and polyphenols are great it sounds like it's your health: more people than just loading go to let my tummy.com/welcome back we are now going to start the second hour of getting project episode 13 I'm joined by your host Dr. Kenneth Brown nonmerit rigor and today's guest is Lafe Harrison he has quite a journey to his current position as Dir. of business operations for election all and dad before we get to life just need to remind you that if you would like to grab your self some are trying to heal gotta love my Tommy.com/spoony use the code's many safes and money that is power packed with polyphenols happens to be the only NSF certified for sport indicate over-the-counter product for IBS and bloating can't but is that mean well that means that we have done rigorous testing on it so if you happen to be an Olympic athlete a college athlete or somebody wants to make sure that what you take there was a recent study that just came out yesterday on how they were warning teenagers lots of increase to ER visits were teenagers returning to weight loss products and sport supplements that the finding lots of nefarious ingredients in their pharmaceutical stuff and that's NSF guarantees that none of that stuff exists and so that's outcome if even if you're an athlete's polyphenols can help you recover they increase nitric oxide to the muscles and they get rid of reactive nitrogen species and reactive oxygen species is Quickstart you know last week I have been there were two physicians that deal with athletes and A's they saw the NSF Marne moniker which doesn't always mean a whole lot to everyone but when you're with athletes it matters to they came up and they said that's really cool that you have that that means that we can use that and I didn't know I knew nothing about NSF until I was contacted by the registered dietitian it was on staff from the Oakland Raiders and wanted to know if I could sell them in bulk Sinatra and Teal for them to distribute amongst the coaches and the wives of players in a civil what about the players and he said Wiley if you not NSF certified is not anything that we can do with it and that's really went through me and I learned that they have a collective bargaining agreement with that includes the recommendations from physicians and dietitians that work in the MLB NFL most NCAA sanctioned whatchamacallit schools they have to adhere to NSF or for cleanliness and the other thing we are such a geek out little bit the polyphenols and are trying to do something really cool related to the under cannabinoid system to assure that is well basically you have your own endogenous cannabinoids that your body uses to stimulate your ECS and it just so happens that FAH is one particular enzyme that breaks down those Indo cannabinoids where they are supposed to function and if you are light in your polyphenol intake that enzyme may be a little bit more reactive than you need to be and so your ECS or your Indo cannabinoid system tense not function at its optimal level so having enough daily polyphenols can actually enhance the ability for your CBD both the oil you CBD you may be taking but as well as your endogenous cannabinoids to work better so one of his recovers and is absorbed this matter until one of the reasons why we teamed up powered by lexical KPMG health CBD is because they do everything right from the beginning to the end soil to bottle there they have certificate of analysis and we have our guest today at Lafe Harrison who happens to be the what is your official title Dir. business development director of business development and his pathway to get there it is really interesting yes it is and what you find out when we get through all of this is that a company like… All is really finding some very intelligent very well-rounded people to bring some legitimacy to this industry which really although it's been around it's been referenced since Chinese medicine 2400 BC or whatever it is a retard little little shows right now it seems really fairly new and there's a lot of people out there, the wild West and so they tracked a guy like you down and working to go through setting one of the cool things is your background we talked about your 40 day fast in the mental discipline and your calling by God to go ahead and do that that shows your character but where you come from I think is absolutely amazing so bad now so you filled out a questionnaire like we ask everyone to do and you were born in Phoenix and then I know if you ended up in Annapolis and the Naval Academy so you my life tell us little bit about what that would drive you to join the Naval the Naval Academy and and what that experience was like in the 80s while this was the 80s so wasn't exactly spoke I was Piccoli without the marijuana I actually grew up in the Midwest in Ohio but believe it or not a group a competitive sailor from probably age 8 on and did well enough that by the time I got through high school I got enough accolades to actually draw the attention of the sailing coach at the Naval Academy and at the time they were like multi-year NCAA champions so minus the sailing well is probably it was probably accommodation two things I got me and one was a sailing one was us is right in that sweet spot of the Reagan Lehman Navy build up for the for the 600 ship Navy at the time so they were just allowing more people in sure and caress you a quick question because whenever people come on the show like I'm two years ago we had Robo on Mike how did you become a professional rodeo got how does one get into saline and like what you start with that right so my dad was an extremely gifted mechanical engineer and through a job change to Ohio he got surrounded by other high-end engineers who were actually in this very high performance sailing world and so they sailed us one type of boat, 505 and this boat was very technically demanding and so for an engineer who could like to tinker on at the same time that's what his draw was but the ask my parents became very good sailors and then I just brought in that world 24 seven whatsit 505 is that calico catamaran or it's it's actually it's metric so it gets stands for like really 5.05 m that was the length of the boat it was just called the 505 but was very similar to some of the high-performance boats they would say looked in the Olympics at the time and so you didn't like start out like when you find like when people become Formula One race car drivers a start on go carts in the work… As you do so there are there are many different kinds of boats to fit many different kinds of of capabilities and goals and so you can really progress sort of graduate almost like you know tadpole to admit oh you know all I can and going up the dolphin you don't get your badges along the way sailing is a lot like that and then coincidentally at the same time as when windsurfing was born so my folks again just happen to be at the right spot where there were less than maybe 8000 windsurfers the entire world this is right at the beginning in the mid-70s they had them so I learned how to do that at the same time so I was almost parallel paths and then again by the time I got to high school I was good enough to you know finish well at national championships and things like that and then from that unexpectedly get the attention of the coach of the Naval Academy and the next thing I know is essentially I did just well enough on SATs and all the other requirements everybody else had that I the opportunity to go that is no joke Naval Academy is a me when you say that it's just immediately total respect to me that's that is an impressive place to get your education without question and then so your expanse the Naval Academy were you on our competitive on the sailing team for all four years are yet I did it for 3 1/2 3 1/2 years I decided to snow last semester to shut it down but it was it was her it was a that was some schedule I mean so if you go from being sort of spy coleus in high school okay right to then bang your on the other extent other extreme of hard regimen hard academics hard hours commitment me know I was probably between it's between academics and sailing I be like you have a few hours a week you know to myself we talk about it with our kids you're your son's age of 17 he is looking at colleges my sons a competitive tennis player you start realizing why when you choose take that scholarship to a college it's a job and no matter what it is was talking about it he went and did rodeo in his college yet in your dislike I don't care if it's football sailing rodeo no matter what you do and that's a job gets a job yet rated the sport probably took 35 to 40 hours a week just on the sport while my goodness what so your experience the Naval Academy beyond the sailing your degree you math I got about her science and mathematics that's fantastic and that not being a about whether brought under looks all right your math acumen I don't think they say that well I had so bit. Probably a lot of your experience along the way is the reason they brought you on and I know when your Naval Academy you you did become a parachutist and so what did that entail what you were trained to jump from planes and what kind of training that right so part of the professionalism the motor professionalism you undergo at the Academy is are you sort of summer experiences that are required so if you think of a normal through three months of summer they fill it up with two in terms of various kinds of training depending on what grade you're at the Academy so one of the summers generally one of those two months that you have to do is set your aunt ureter on a ship or you're getting a variety of sort of worldwide naval experience of submarines aircraft the Marines all kinds of things very cool but the other month is more elective and if you could pass the required tests you could do things like go to Army Airborne school at Fort Benning Georgia where the soldiers go we could get scuba training or jungle training in Panama there were all kinds of things at that time this is your electric playing going to be in the jungle to raise cool man was bowling so you see you selected to go to Georgia and jump on a plane what was that like it was okay I mean notes the Army way so they took three weeks to teach you something you can learn in a week so just in San Antonio where I said that we were just there but I did my training and so we would have to rotate your fellowship at Wilford Hall and Brooke Army base and totally cracked jokes like that the whole time on each other generate yeah it's inevitable it never stops so it's funny because you know you go through this training and it's you know it's the Army world and you just have to play ball for a few weeks but it's also the same training that that seals would go to after buds because it was the only sort of real formal basic parachuting school to go to like the Army would send their rangers to her their airborne guys to that type of thing those guys would just stand there and laugh the whole time I mean the Army you know sergeants running this program they didn't even know what to do with them but this is just some boxer seals had to check it out to her for those guys standing around and you wouldn't touch him with a 10 foot pole but you know you're just trying to like that with the young soldiers notice these other kinds of guys out there and

christmas god tv american amazon california canada europe uk bible internet washington france mexico olympic games british americans french west research colorado africa chinese ohio russian ny er development ireland army hawaii institute veterans fb white house scotland ptsd academy mba cnn va ncaa walmart navy museum world war ii fasting mac midwest senate alzheimer's disease adolf hitler joe rogan cbd lol san antonio bc ot clinton cold war pe moscow powell ethical boeing soviet union bridges panama mediterranean soviet marines pepsi omaha att ramadan frank sinatra jordan peterson gut health thursday night football us navy d day ibs town hall roosevelt robo tcu wiley hemp aol kpmg crohn ussr mlm nazi germany lakes naval john wayne la fe world war iii normandy bsc cheetos hashimoto mb allied oakland raiders formula one yugoslavia lax lps midsummer annapolis leif quito teal naval academy indo decatur geico chiron cpd kleenex tinker mds endo sats artie nsf fd stiles pea tommy hilfiger piccoli quickstart farmville jg charon gcp us naval academy mcwilliams sean baker ecs milgram irby mlb nfl alcala wichita falls pavlovian jepson doug brown rother ifp polyphenols fluor burly soucy acheron jw marriott pef rbl ifn idsa kim brown bmd coas cd1 gorky park bob gardner fah melanie avalon kenneth brown army airborne elixinol atrantil rick moore joy beckerman

Hammer Man, NBS, PTSD, Selfie danger, Dropping IQs, and more

SIBO SOS™ with Shivan Sarna

Play Episode Listen Later May 23, 2019 117:14

Ken & Eric tackle the outlying topics, nice GCP show contest, learn about NBS (Narcotic Bowel Syndrome), selfies are killing people, PTSD and med marijuana in Texas... Drop in the GCP and enjoy DR. Brown addressing the topics that could be shaping the world around you.https://lovemytummy.com/spoonyhttps://gutcheckproject.comNancy husband and wife may kiss the bride connectivity care whenever you need video chatting with the doctor right from your phone so I don't need stitches thank you Dr. United healthcare health plan benefits may vary welcome to the projects with your host Dr. Ken Brown I Eric Rieger will we all check our egos at the door and nothing is off the table again what happened man we are on episode number 12 we are big doesn't it is a big dozen so it's always like this on this is like a recap episode were just going to cover a lot of stuff just you and I and really really really cool like this is super exciting so on we call this episode topic talk simply because next week we actually will be out of town to go to IFN down in San Antonio the functional medicine Society corrected outwardly running the booth there outfront you there and I FM in San Antonio I love San Antonio it's a great city absolutely and it's kinda wild so if you never heard of IFN we have tried for this is our third year it's so popular but even though we were asked by the IFN to go ahead and be a part of the show we just wait we can sign up in time they heavily that everyone is going to be a part of the show they wanted John Teal in this year now they've moved venues to a larger one John Teal was definitely invited were really really excited to be there on behalf of trying to heal so looking forward to the show next week on how the Antonia I love the functional medicine doctors because they are open to just talk about checking your ego at the door they will at least listen to anything at all prior episodes episode number 12 we covered a lot of things that could be considered a little bit atypical you know the photo bio modulation things CBD talked to were always doing all that kind of stuff himself stem cells that stuff is novel and it's the functional medicine community it typically leads the way and they start using it and then we can start getting some data and then we can start putting into traditional medicine definitely so today's today show we decided we would kind of reset we got a great contest to remind everybody about we've got does some some viewer emails that have suggested some incredible topics to one of their particular from the believe it's leaves David and I were going to get to that in a moment but can a reset of course to begin speaking about trying to heal if you ever suffer from bloating or abdominal discomfort get yourself your daily polyphenols with all trying to heal go to love my tummy.com/spoony love my tummy.com/20 why/spoony can muddy think would say that because it makes everybody a winner when you put in the code spooning you out of the vision rolled into our discount contest in your hundred percent guaranteed to get a huge savings on this so SPO and why putting codes booty definitely so love my tummy.com/spoony spoony so the network continues to grow the popularity continues to grow I checked out trays chow down again just as last week I'm a terrible cook you know this I'm getting a a nice girl sets a big green egg yeah green egg having him come in the worst on the grill but now I follow directions I can actually what makes food the people will eat not just the menagerie of animals that is charred remains and I you know is less easily but no it's is a lot of fun but Trey shot out is got great information check them out on the spinning networks money.com has a full lineup of his ally would be all the times that I realize there are a lot of people who catch the repeat go to spoony.com and you can see for all of the shows but definitely trays chow down where it finishes and where it re-airs throughout the week awesome the one of things only try with you okay right now just I realize I think one of the things we should do is continue to grow intellectually okay you know that I like to read the daily stoic every day they always have quotes from scholars Jeff Solomon read you a quote but I want you to tell me which scholars said this okay this sounds hard yes it's gonna be really difficult okay I am probably in the sky flying with the fish or maybe in the ocean swimming with the pigeons see my world is different I'll give you a hint okay who loves lasagna oh is this this is God belittling this little why I should've known that now yeah yeah I know that's good he had a real Jesus movement sounds like lasagna I got in real Jesus move in silence like lasagna yeah man I got as deep on lyrics sure that's funny so what do you what you are going on as best we can mass past weekend was the beer I have a stuff like essay on repeat but where were back into into basketball and hip so that a couple times I have said that 12 times the exact I know no doubt and debit actually this last Sunday because of basketball the boys missed they miss their traditional celebration with with mom so Marie and the boys went drove I went drove vast electric go carts which we are introduced to backhaul crewmen knock her out in California I think you may miss that woman I want to go with them in thesis racetrack called K-1 and I have one now here in Dallas and that means great they loved it K-1 the one that so I did one when I was it I was given a lecture at ECG I went to the morrow and ready one and it's it's basically a tract that has light turns that little beat dips up the down it's not just a straight flat what was this one that is deathly not flat but I don't think it has any bridge volley or anything else I can think it's all routine S-curve about it but it is deftly technical and of course the boys and Marie came back and they send in one's great number to their surprise at the max speed limit is 45 and Max said my youngest he said that's scary scary dad but nope I really want to be out jet when you were almost tight turns like that oh yeah yeah for sure so the great Mother's Day no not typical but really not typical she liked do I do things are adventurous so that was that it was deathly fun for them speaking of carts do you remember when our good friend Russ ironic Dr. Veronica San Antonio which were to be seen next week sure he called into the show when we were talking about Lou Gehrig's disease and you know the effect is that dying of that right one of his good friends their son was a go Carter like always the child became really good when on the circuit and now like races for Porsche no way is like a 18 or something cool scratches will tell Mac to stick with it just seemed it seems so hard and I know it's it's a career pathway that I'm completely ignorant to I don't know how they how they get to that point where was someone said when I want you to drive for my team even though I'm pouring millions of dollars in this car in for a crew and equipment etc. that just seems it seems while was not sunny like okay you look it's you wonder how people end up in certain sports like for instance Tim Duncan was when he was a swimmer yeah you know if Michael Phelps didn't jump into the pool what would you be doing in certain countries they certainly communist countries were back in the day when they would find Olympic athletes they would like looked like you you're to be a power lifter based on X, Y, and Z user to do this I don't know yet so that give you a Tim Duncan is doing now no I believe that he has been training as an MMA fighter post-NBA career no way I yeah I'm certain I read that somewhere but yet that's that's what he spends his time doing is its MMA training etc. mean so from awesome swimmer if I remember correctly story about Tim Duncan I don't think that he I think that he really played competitive basketball until was a very late team and then went on to and he and Junior hide in play and then he did start planes like his junior senior high school maybe I do it one time I don't member the whole sword hung up as I was we lived in San Antonio I saw San Antonio and I had the David Robinson and Tim Duncan team and they were just an incredible team to watch so focused individual for sure how you know what I did not tell you crazy story so you knew I was in San Antonio two weeks ago the family okay I taste funny story sup with a family and we use over and lift whenever we go on vacation it just it just takes away the anxiety of having to wonder where you can go and even though you may be familiar with and it was a town just is easier nobody can hop in a you joy your conversation you go out to eat happen to a new girl after something some kind of rideshare something like that well after one of the games we often do one of these ride shares and were going back to our hotel which is down in downtown San Antonio which is going through a great renovation of of Regent application and it didn't do a lot clean up I mean there's cities do that they Evan flow and San Antonio is kind of on the uptake right now so it is starting to really kinda come together but we stayed at this new hotel that just open nothing months ago and were making our way down the road and the traffic jam begins to kind of near Jack is bottlenecking because there's construction and we see seal vacationers tourists like to know what they are what parts on a cousin over in downtown will probably like Riverwalk area area now, probably like two blocks away from Riverwalk itself where where we are on the car but you can see tourists making their way to the Riverwalk area and I believe our hotel backed up to it so about 2 1/2 three blocks away from our hotel's hotels nice really nice well so on one side you see tourist making away on the other side you see where the the economic developer has a quite started but it looks like to get some preparations forward to redoing the road and there's just a group of just random folks I'm okay and one gentleman grabbed my attention because he stood out and is wearing on the tour side are only not on the terrace okay he looked like he knew where he was but not everyone else really knew if he knew where he was whole and he had a tie-dye shirt on and it was his kind dirtying in and tatted me up that happens on our tattered tatted but that tattered and I hit on some camo shorts and lots of keys like EEE can probably open up most of the doors and Senate just like on the changes this is a big ring and a Dave they look very noisy I can tell of it was that was an alert bell that he made for himself or he really had access to lots and lots of places but since we this gigantic ring of keys and he's kind of looking at some of the key master from the court or Ghostbusters it doesn't really matter and at this point he's looking it away and were stopped in traffic which is bottlenecked as a red light and he's, looking closely cars and then kind of checking them out now and I'm still not thinking too much of it but I did I just noticed you like holding keys up to I think this will work to put my name in there now it it it what wasn't quite like that but then suddenly he just decides to make his way in there's just these two trash cans there's a black one as a blue and but that they are identical and in shape and whatnot but it's the big metal was a kind bow out there there meant to be on the sidewalk easy for passage and you throw garbage and it will he walks past the black one with intent and then dips his head down into the blue which was the second with complete intent and he's only in there for half a second because he reaches in and he grab something right away so he it appears to me he knows this is in there and is he brings it up he's holding a handle and he's basically shaking off will looks like trash can juicer trash can do what I want to it's it's it's a really really rare fruit but and in most urban settings you'll find this this trashcan fruit in you and then you can squeeze the juice yes you can always squeeze the trashcan or as later my my my family decide that I think that's just blood because what it will hence was a no go was a hammer it was about 18 inches long and then he picks it up and looks at it turns it from side to side glances that all of the cars and then sets the hammer down and put his hands on his hips and so the key master of San Antonio yes nothing happened was trash Nancy standing there and then all of a sudden he just bypasses and realizes that he remembered where he left that hammer he said I guess he was in the marinating and I'm not really sure what was going on but it was read it was really interesting because then I found myself feeling like a fish in a fishbowl I we hopped out I don't know what we do and why is he looking at our car was he looking at the other cars what to do with those keys once you hammer how do you know is in there what's that juice so anyway I just I found myself wondering what puts someone in that situation but he had he had no conversation with anyone around it is probably 5 to 10 people walking passing by and then is he just kind of zoning out scanning vehicles watching them bottleneck he just decided well it's time on going to go ahead and pulled his hammer out and he didn't go and do anything with it he just stared at cars every set it down and then kept staring at the hammer and then staring at cars and then finally we moved hello you guys in traffic I saw is bottlenecked seriously in any way we we've gone from two lanes down to one but finally the light turned green and slowly we made our way and have I was happy-seemed like a bully expecting Russ to call in again like this will go much so here in San Antonio you know hammering like little back story here because words do filled in that or just maybe he's looking for a second nails I don't know he's looking for something it's given given the door to open given some construction project to do he's ready he's ready to build really quick that it's funny that you brought the goober live thing because on the news this morning they were talking about how certain industries just disrupt everything what we know that with completely disrupted the whole transportation sure catches whatever everything well because of the Over and lift drivers now in certain airports will do this in certain places this whole article came out about how at the Washington airport I think with the Reagan airport Washington broom lift drivers would get together and they would all turn off their apps for two minutes and what that would do is in the algorithm of bring with okay it would show that there is a lack of drivers in that area and increase the fair yeah so they were genius they would all do it together at the same time so that they could increase their fares you know how it says oh fair increased high-volume time it's a really highborn time that you have a lack of drive right and so they all get together it's technically illegal in the Buber and lift driver handbook handshake whatever it is the cheater there been other things that happened in Newbern lifts the would that be considered price-fixing I'm here 100% is considered price-fixing that means what would it be on the action of the other drivers are doing I'm just curious because their action at the one putting in the algorithm for the fair increase it's technically over and lift or any of the others who are doing that they are there calculating it by their scarcity so these drivers are just on their there free to turn their phones on and off the other actually saying that what the will do that but here's the here's the quote every night several times a night to relive drivers at Reagan National Airport simultaneously turn off the rideshare apps for a minute or two to trick the app into thinking that there are no drivers available creating a price search when the fair gets high enough they all agree it's time and they turn it back on so they probably are just sitting there searching to see what the cost is everybody sit there waiting and it's like old hold go to Braveheart and that's nice now that's really interesting but I mean if you think about it I mean that's that's the access that's it's the loop all right that's what everyone does they find loopholes they find it the path of least resistance there thereafter to make money I mean that's some of them that's that's their job that's just but it drives me nuts because I mean you know I've been to let conventions like that like natural Expo West or when thousands of people suddenly walked out of the building with some massive conference and you go to that group or a new light the fair just quadrupled oh yeah just coming that's nuts we've been that even the Lubbock and so I've gone out there to either sport and I met the one driver low but by the way the wind so I I've been out there for for game day now for it to take the ball game or even basketball and when it's not you want to take an Uber you can go from one side of town to the other it's very easy drive people drive friendly at their it's super super easy is never congested you can make one side of the other in about 10 minutes no matter where you are there may be $10 at most but on game day you can easily see it going just from being at the campus which is around the 4th to 19th area and then head over to 50th you may see the fair as much is 35 bucks just to get your going to meet people for for dinner whatever after a game but yeah that's I always wondered that because it's not it's done at the hard to hail the Uber why the fair increases it silly just because you can because that's really what it is why think I think it all comes down to that I think the algorithm sure that is basically there's a load a need or the drivers are being used up the fair will increase I think is to incentivize other drivers that are on break or whatever to down and out to get out and do that and I don't know I've never lived under the rug she had friends who been in between jobs and it's been it's been great for them to be able to supplement income is really some I don't know do do Cooper drivers airlift drivers get like in an alert that taxpayers are increasing they wanted turn your the cab I don't owe very much like John Wick with the assassins when the yeah they tell about the alert's time it's time to go back in business and help in my car so what what is happening in the Brown household at the moment well we got kind of proud of Lucas tonight he is being inducted into the national honor Society who is nice this is interesting right over here in Colleyville which means I don't have to go to farm and hang out here just work here in this lovely Fort Worth area no joke what I meant drag a five minute drive yeah it's nice for you Lloyd is complaining that it's at 5 o'clock in Colleyville and like to meet you there it's so proud little guy doing the title of the Internet and, she's she's been Judy named Shiva name to the list man so the school this public school the school that Carly goes to has some really smart kids and it is very proud of Carla she got always wish of this presidential award right and they gave always other awards and this is it the school goes up to the eighth grade and one of the awards that they gave was the when Duke invites kids to take the SAT tips five tips are some general but it's the real SAG that I get in there put the same pools although the high schoolers they had at the school seventh and eighth graders they had like 12 of a score over the 95th percentile 95th percentile compared to high school senior US why probably US white while yeah that's why I'm so proud of of my daughter for you and straight A's in school that is academically extremely competitive wow well that's that's just a curiosity so I your and your oldest Lucas he's been doing home so now for this last year so that he could do the touring that he needs to do for tennis house that has a working out for him both working out that's why were doing this over here it's actually considered great by public school but does everything online) it's just because of his schedule it's just one of those things you can't miss is what schools he doesn't so great I call it was actually pretty well known throughout Texas for their curriculums that's really interesting they seem really innovative account on top of it it's a little so far it's worked really well in ways they don't like it and that's also siding the usual stuff so I think next year when he goes to high school he's going to try and integrate himself a little bit with some of the extracurricular type stuff but there's something that will and in that makes sense though so he can be he would be involved kind in the club activities of people his own peers and have some more social interaction but it's not like you didn't have any this last year he's got on me I hear you bring it the same names over and over again that is a tennis cohort said he sees on the road Weatherby from the West Coast or down to Florida he just sees them sets kind of his colleagues the moment it's pretty much the colleagues I mean everybody get out to some of the basketball menu guys do is run these different circles and sure you know you just end up becoming friends the parents become friends know the boys liked (different ages notes it's the beauty of life just can't get yourself exposed to get out there little bit speak of exposed your boys are not should say speaking of exposure that's all that is all right yeah well I was always dance up that I had a great time seeing your family at generosity feeds once told him about the man Ronco blending while huge contact that we met out at dead baby bathwater and note big shout out to Hollis Mladic for knowing exactly who to who would include net group so ill for the listeners Dr. Brown here is he doesn't say to himself as one of the most altruistic people without ever saying it and basically we took the company they were starting here we have that I don't have the sick as I have it tattooed on my lower back but debit for the CBD and the research and are trying to heal we always want to find the best avenues to give back to the public and sometimes weekly letter window when we do it sometimes we don't but this last week it was really cool we get to talk about a little bit because it took a lot of pictures and his generosity feeds and Rocco Bundy with mod pizza they go to a lot of different urban areas I think almost every weekend and they recruit people to come in and pack meals in this last Saturday it was Saturday Saturday yeah we we packed 11,000 meals for needy children in 44 minutes 44 minutes in the DFW area what something I did not know is that one in five kids the only food that they get is actually at school in certain in certain urban areas because of the the lunch program that's the only meal that they get so that they may go the whole weekend without food that's what this is for us to stick food in their backpacks so that they can eat there was a really cool thing and actually when I was even also equally impressed with was the quality of the ingredients they were pulling out to make those suits that were on the go that it wasn't just beans and it wasn't just beef it was high quality beef broth Max etc. they they want to feed the kids a nutritious meal when not to say hello a look we give them some rice the complex Caritas like that you have the protein you've got a the rule base for the libido fat that's awesome was I totally agree and pack and that those you are doing doing charity like that once in a while just remind you that there there are people out there that are quiet but they may not be getting the the basic needs of life that it was it was a lot of fun Ron thank you so much for the invitation and of course he's he's been a great template on showing us what we can do to engage in more charity getting back with the companies and we we plan to take full opportunity to do so that was a quick half-hour next time I will already already get into a research topic in the next half-hour we had a talk about the dangers of selfies really interesting statistics there had what's going on that you in developed countries not building see here a little bit so 12 I have thousands of aspiring authors teamed up with Christian faith publishing to publish their blog because Christian faith publishing is an author friendly publisher who understands that your labor is more than just a book we provide authors freedom and flexibility throughout the publishing process professional book editing award-winning design and some of the highest royalty structures in the publishing industry and is always you will retain 100% of the rights to your book I was looking to find a company that I could trust one that assisted in the editing process completely Christian trade publishing will publish market and sell your books in all major bookstores and online booksellers as well especially Christian bookstores call for your free author submission kit 800-978-4812 800-978-4812 800-978-4812 that's 800-978-4812 Dr. come around here a host of project with my cohost Eric Rieger I've seen in my practice that I'm trying to is a whole lot more than just the bloating product yes it is a whole lot more than just exploding because of the polyphenols that you find in Alicante what is looking to these polyphenols beware these polyphenols help you have more energy and polyphenols are great sounds like it's good health: more people than just loading go to love my family.com/take the pain out of ordering your diabetic testing supplies with diet thrive diatribe ships the testing supplies you need directly to you when you need them best of all with plans starting as low as eight dollars a month diatribe is probably going to cost you less than what you're paying today diatribe is so convinced that you love their service they're offering your first month of supplies three simply type the Kodak DOC and checkout diet Thrive.com that's DIA Thrive.com okay that is now the second half hour at episode 12 that check project is reminding your break I completely forgot to hit on something that was important even said I was going to do it the top of the last half hour and forgot so what was tests I now when I forget probably because I'm not training radio so you do a lot of things were not trained definitely heavily do so gut check project we want to reward the listeners and we already had people who have responded heavenly appreciated everyone so far has sent me examples of doing this through iTunes and that's great so keep that up but essentially the contest to win a free month supply of Voltron teal and a free KB MD CBD flavor of your choice whether it be natural or sentiment is simply have to go to you YouTube or iTunes or really both and then subscribe take a screenshot send me an email which all you have to do is go to get your project.com go to connect you'll see on there you can select the message it says I subscribe 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a huge discount you to save money right there your home your phone for you looking at what I'm laughing because remember okay the top of the hour I said I want to be more intellectual with you which scholars said I'm probably in the sky fly with the fish or maybe in the ocean swimming with the pigeons Jesse my world is different I give you a hint that I said has something to do with lasagna will my wife Loida just texted me and she said with that I thought it was Garfield legal scholar Garfield right you actually probably on equal footing just in two different ways I got the logical thing to say he did a political basis is a lazy cat what you think about that is that is AAA really really lazy cat that made his own cartoon no being that lazy is pretty successful towards Casca but you know you're not lazy I know you have a research topic that you want to get to I do want to get to that but first I want there's some cool stuff that's happened in the news recently I was forwarded an email that House Bill 3703 in Austin patients will now be able to have access to the states medical marijuana program if they been diagnosed with medical seizures multiple sclerosis terminal cancer incurable Alzheimer's Parkinson's Huntington's autism and Lou Gehrig's disease and we we often talk about Alzheimer's Lou Gehrig's disease and autism we talked about that a lot so this is this bill did pass in Austin yesterday I think is what passed those pretty one thing the people were little upset about is that they did not allow PTSD which is honestly very very common but PTSD know that is interesting do you think that what number one the exclusion of it it just this is a unique to the medical field either legislators are elected to make these decisions don't you think it's kind of strange though that probably there's a lack of expert opinion in helping shape things and applied to someone who would have the knowledge to do that you got elected person who has any idea what their background is in essentially they are the ones determining what the best sciences to make a decision for who can have access to something so I had a patient that is a patent attorney and there's some patent laws that her changing and she got together with a bunch of other patent attorneys and other offices and they got hold of the senator into I think I would get this wrong but basically to have a lunch with him to explain why the bill that's presented is not a good one and it will lead to patent issues Robert has a little date they hide stuff and that it cost like $50,000 to have lunch with oh my educate go to okay yeah but I mean what is the money go to the coast to the campaign or to go through whatever but the whole point is is who gets to the person that makes the vote just as make sense it's that's tough and you know the whole PTSD thing that's what my actual article is on but it's it's pretty thick it's pretty cool to get into that but there's a reason why I really do think that we need other treatments for these diseases that right now in the medical field we don't have good treatment for and people are self-medicating all over the place onto a quick story before you get that research his adjuster mommy and I did not share this with you this last week but you know that I do I blocks for another friend of mine now ophthalmologist Dr. Rogers Eckhart fantastic out the mobs by way of indenting so we had a patient who came in older German served Vietnam service country proudly he's basically been relegated to the VA for his his healthcare to get chronic pain my pain issues this particular patient did and he came in with some bad pain so he couldn't get under control and the person overseeing his care at the VA has determined now that he will not refill the OxyContin or wherever he was on I can't protect which one it was a HUD known size hardcode on hydrocodone that he was currently on he's not getting any more because they felt like it it it kept increasing hey base was getting diminishing returns they just are stopping it for a while will basically what that did is it allowed his blood pressure to increase to Heinz where we could do the procedure so this poor man it is relying on the VA etc. he begins to pour his heart out to me says I've gone to the VA I tell them I am in pain and they're telling me that all I'm trying to do is raise the dose I have no interest in quota quote being high or anything else like that and then he went on to tell me something did just Kelly shattered and shatter me when I hear you talk about the marijuana lawn it's great that they're opening up access but he went on to tell me that 3 1/2 years ago he had gone out of state to Colorado with his family and was able to obtain marijuana legally in Colorado and that his pain threat or is is obtained for the threshold I guess technically in his in his description, went up the threshold went up and the pain went down any had great comfort he was able to sleep for the first time and will able to go to the bathroom without issues and so when I hear that and he returns here and he said he was then worn by the VA when he began to talk to his doctor about it if he were to test positive he may be kicked out of the availability to get his hydrocodone here while he still in Texas it just what what kind of service are we allowing these people to get this poor man now he couldn't get his it will be good to scatter so I mean if you stop and think about that this is the problem when I went to medical school we were told you can you have to know one of the five things you have to make sure that you take care of it's a vital sign pain is now vital sign I what is your pain level if you're if you have somebody was in pain you are obligated to treat that paint and we were told that don't worry you can get people Vicodin all this other stuff because is always a real pain there will be no addiction issues that is not true not true at all we learn that one like right now were still learning it that's also excited to see that Denver at least decriminalize the use of soul Sieben yeah because there are trials going on right now silicide is extremely effective in PTSD and you and I had a long talk with Dennis McKenna right and that psilocybin is the actual molecule bits and mushrooms the people described as mushrooms the hallucinogenic mushroom but that civil Sieben really does some interesting neurologic stuff and somebody was a huge part of that is Joe Rogan Brian I was listening to item number which one it was Joe Rogan was on and that they kept talking about doing suicide and in various doses and how micro-dosing is actually something that a lot of people are doing a lot of very successful CEOs are doing so it was with Jorge my hospital is an MMA fighter name in MMA fighter they were talking about where Jorge did some bro science it took a little too much mushrooms is pretty funny episode but I always get back to this we we create this problem and then what would you do is were just going to say no not to give you anymore because we know like almost everything else that you take caffeine included I can have 67 cups of coffee and I'm perfectly fine because I drink a lot of coffee my receptors down regulate the response to which that's can happen with opioids this can happen with everything and when somebody needs more to achieve the same pain level is not necessary that the third seeking more for the addiction property you literally will start having pain at the same dose I have to keep going up and then we withdraw people get into note they go through withdrawal it's a legitimate addiction go through withdrawal and then nearby Gustavus of compensatory mechanisms that basically just like this gentleman was experienced with high blood pressure now we can't his vision now suffers his quality of life is going down because he's in chronic pain he's having to be wheeled around by his daughter it's in she's in tears as were saying it's just not safe to do your eye right now we wanted someone so badly to do it but high pressure hi ocular pressure and blood pressure can lead to a rupture and then he would just lose vision in his eye altogether so unfortunately we had to just reschedule high blood pressure due to withdrawal symptoms distribute an anxiety component to maintain component to it and when you say that you can't sleep sleep is the most important medicine the one thing if I can get one thing for all my patients to do get a good night sleep because so much stuff goes on that heals your body that makes you better while you can sleep so that's one of the reasons why I'm so adamant that when we launch this health box the D had health box you we will make sure the people can heal their brains get some sleep there to have more energy all of it works together if we can get people feeling better definitely and hereby to touch on that PTSD did it before you get to that hinge is one second one more thing on the veterans here's what I think some people forget whenever the federal government prevents us from doing research on a particular substance it's just that means there is no innovation it's really legally allowed to be had so keep in mind that most of the movement for us to move forward to have evidence-based practice or protocols I should say using medical marijuana helping states like Colorado and California kind of set us on the track way were we can start looking at THC and other substances came from Israel because we prevented it from happening here but they were specifically interested in taking care of people that serve their military which is everyone has to do two years over there we should be taking better care of our veterans here they have sacrificed their time and for the most part several years of earning power to simply serve their country and it just doesn't make sense that when it comes time to take care of them in and I'm in a situation where they are in direct need and we've essentially used them as a country to serve us why we turn them away it just doesn't make sense that we did that's that's the system that they have to exist we were talking there is a friend of mine and Rich Hagedorn out of vogue in Omaha Nebraska one from the date he's part of founding member of soldier Valley spirits words they actually get proceeds to veterans so they got their own there making different whiskeys winning awards doing that kind of stuff and they give a certain percentage all the time to our veterans which is cool and it's only veterans that work so super cool I wish to have them on yeah I know he's really really really funny guy super high-energy two quick things on the opioid thing To do so in the news yesterday that a small study came out oh New York Northeast I can't remember see it's not ethical is Mount Sinai I think him on Mount Sinai where they took a small number of people that were heroin addicts and they actually gave them marijuana okay CBD CBD I hope to see I haven't read the article just on the news I want I need to get that article and they it really helped with OP addiction so we got that question brought up in one of the shows about does does CB do you know you always be careful about making claims but when a study comes out because I'm not making a claim I'm referring to the study the study showed that they were able to get some of these opioid heroin addicted people off of heroin using CBD now I did not see it but it does sound incredibly annoying but that's just have to be no topic for a show to follow up with because I don't know but it sounds incredible and just think four years ago that kind of research wouldn't exist certain that stateside no effect on the news director talk and that most of the research coming out of Israel or Canada now now since Canada's the get into a little bit direction looking at it what was the name of the person that emailed you about have you ever heard of narcotic bowels that was David David H LLC last name on it that's what something you give me permission to do but to David and what he did as he specifically brought them into our attention at David thank you this was an awesome email basically saying that articles date back to 1987 and then several of them the NIH has posted two articles on it and then nine 2007 they were even revised in 2017 and it's a condition called NBS or narcotic bowel syndrome just like I Dr. Brown said coming there's a there's actually a lot of legitimate research that behind it and his his claim here is by physicians and pharmacist are completely unaware of it even being a problem but I mean you are you being a G.I. maybe you did know by this moniker but you kinda seem the symptom occur I have I've had a couple patients and you're almost chasing me almost on the acculturation of the Dragon because this is fascinating you can be taking opioids for let's say back pain the motor vehicle accident you get the chronic back pain drawn opioids and a very weird thing can happen this narcotic bowel syndrome actually when you're on opioids it can actually change the motility of the intestines and we know that which is motility you can allow bacteria to grow which means you can have more gas produced and it actually causes something called hyperalgesia so your visceral sensitivity goes up in a paradoxical way song to say this again you take opioids for back pain but your gut actually ignores the opioids and hurts worse so I've had people on opioids and they look like their pain seekers is like my belly really hurts and you realize we could get you off these opioids and that's what I've done with about four patients the whole point was trying get them off cold and in the medical terms called opioid induced hyperalgesia so it's a characterized by paradoxical response people that are getting opioids suddenly now what's interesting is that doesn't just happen in the gut we have a term for there is a possible tapping other places in your body words like oh now this art will all be lowering the pain threshold in other places where what happens what happens acutely and that in hospital course would be blood have too many opioids one of the first things I complained about it it almost always starts with the nose but it can spread out to the body that's the itching you have had this conversation before many times the first thing that's prescribed to them is Benadryl and unfortunately it's not a histamine mediated itching response at all that will do nothing you need to use unfortunately to offset the opioid drug yet to get a opioid mix agonist antagonist did like it like a new vein or something like that to make the itching stop because the Benadryl simply will just stop histamine makes him tired so that it is fall asleep itchy and you not really doing anything unfortunately it can take someone to another state where since the opioid suppress respiratory drive and not being awake actually will drive down your respiratory rate as well that's a natural response that you get rest so it's just a bad combination Ali around when especially when in today's day and age mostly outside of anesthesia trained people the first thing people reach for is not an all an opioid agonist antagonist to handle it when you and I had a conversation first I thought of I was an intern in San Antonio how about 2 AM called by a nurse we give this patient's pain medicines and I was itching everywhere 0.5 Benadryl what he is normally your intern I learned something early on this is advice to anybody that's doing a career when you find someone who's been doing it a lot longer knew no matter what their title is listen little. I've always so we had to rotate with the military in the military you know if you go in as a doctor you automatically going as a captain so your officer right but you do whatever that master sergeant says yeah so I made my life real easy but when I was at the VA in the ICU I would just I would defer to the nurses that were there for 30 years be like you teach me even do a little longer I've been here a week elevating that eight years but you're exactly right maybe we we didn't want us coming up through the anesthesia training I can remember you would have's fantastic scrub techs have done lots more hearts and I had time and they were there great onset of ALU but you just listen to them because they help you but it makes sense so when I first came in the practice of I was doing a lot of L2 lot ERCP's at medical city Plano :-) RCB is yes it's where it's it's called an endoscopic retrograde calendula pancreas talk big sculptors through the scope that you just go down like an endoscope and you go up into the liver and into the Pancras thank goodness it was fun at that time it was that Dr. my partner Dr. Goldschmidt and now we have Dr. Ackerman who are both experts in it so as it turns out it's a skill yeah but the more you do the better you get but is pretty funny because the ERCP team that was there you know I'm your new and you try to act like you know what you're doing and you like to know get me the jagged whatever and something else but you had a thousand hot water so I was always trust in this nurse had he has been there forever and he would hand me the stuff and he's hilarious is from the Philippines get a real call nature and so what you do is you get into the you get into the bile duct and you cut so you can pull stones out and do stuff like that and Moses said I no longer do ERCP skills we got better experts doing it but I'm doing it and I'm making this cut and I look over at Henny and I'm like that's that's good right knee goes I think you need a little bit more and know it in the just red blood everywhere you go Steph was too much but in the next hour trying to stop the bleeding sores like that run like yeah well you ask the experts are there for a reason people to specialize and thankfully they do give enough time to tackle this will I just want to bring up another interesting news stories uncovered were kind of all over the map here but a story just came out today a woman from Greenville South Carolina is suing Burger King because she claims that she was diagnosed with irritable bowel syndrome after suffering symptoms since eating improperly cooked food at the restaurant she's asking for $330,000 for medical expenses missed work medication gas mileage as well as public embarrassment excessive weight loss and additional damages while all I mean a lot of different things to think of their I may not obviously probably most fast food I don't want to name Burger King specifically the probably most fast food is not the best kind of food to eat but I think most of us should know that I now what he think well what I think is really interesting to me is that we know that 20% of people that have a gastroenteritis no matter what the cause of right May not a big burger again maybe it was whatever the matter what the cause 20% of them will actually develop a disk motility meeting your intestines will not move very well allow bacteria to grow and then you suffer all the symptoms what is striking is she's been doing this for years was several years before that she said that this happened in she was then labeled as debt as irritable bowel that's lysine clinical the time literally all day long people, no I meant I was perfectly fine I traveled somewhere and I came back we talk about veterans there's a lot of people that when they do a tour someplace else they get sick select 20% of the Dr. Mark Pimentel I still think he's doing the study is doing a study on veterans a comeback and the burden of irritable bowel syndrome people get labeled is actually something fixable and that's how we develop ultra until summer in the story and I'm like I was poor woman just a doctrine to yeah ors I fax and depending on what type of bacteria is an ARM is going to call an audible here I think we had to move your study to that to the next half hour so we have enough time that takes me to another topic one of the places that actually carries her KB ending CBD had a question and she her name is Jacqueline up in Oklahoma and she was asking me what is the connection of why people may suffer insomnia and I'm I know you have talked about a couple different mechanisms mechanisms but also thought about another one I want to run this by you so whenever we have inflammation some a marker histamine right so histamine of courses is something that basically races whenever we have cutting abrasion we have in it an insult we can have history right this minicourse is one of those that works in awake center that keeps us awake so if we have chronic inflammation just like we were talking a while ago when you give someone Benadryl they don't necessarily need it you're blocking histamine they get tired if you have chronic inflammation you have this you have a meta-chemical messenger in your body that circulating that your body is producing being histamine making you stay awake and alert because technically your body thinks it's under distress needs to go and do something about it so until you can basically control and slow down inflammation and get some level of handle on that it would seem yet another natural reason why it would make sense to have a healthy Indo cannabinoids system to slow down the histamine response so the you don't have over information yet and I think it's it's that such is his remember the histamines be released by the mast cell right and that's part of a cascade of inflammatory markers there's all kinds Tina fell for aisle 12 mile 23 all these things were learning more and more about and last week was a little bit before we discussed how when you have leaky gut you can have leaky brain your blood brain barrier action becomes permeable to these inflammatory molecules these inflammatory molecules can then reside in the hippocampus which is your sleep center and you don't sleep well and then it becomes this horrible cycle which many Americans are actually a stress is a good thing acutely acutely rise your body adapts to chronic stress no that's really were talking about we just talked about the gentleman that was that the VA chronic pain chronic inflammation chronic stress that's that's the problem stressors are not bad at all when you work out to grow muscle you if you think hard and then you take of you know you rest and then your brain rearranges but I like the histamine example only because for some people that are new to learning why inflammation may be tied to their insomnia most people have at least either experience or had a close one experience taking something like Benadryl diphenhydramine and they get sleepy it's because you're blocking histamine but it think of the thought about that and I guess with your anesthesia training you certainly are much more knowledgeable about the depths of sleep and the stages of sleep and things like that because you have to make sure that somebody doesn't run away bad bad luck there is that's so funny you're going on this route this morning when I was working out I was listening to I listen to a podcast called health hacker members name but he had his guess today was a MD called Dale Broadus he wrote a book it's all about preventing Alzheimer's so Alzheimer's and dementia is becoming one of the leading causes of burden on the US and death and all the stuff she showed something which is really interesting bit typically in the US we start becoming ill around 40 restart in diagnosed with chronic illnesses in the UK it's around 50 so what he was saying is that we may be living long but are six times longer here which ultimately the longer your sick so if you have chronic diabetes if you have sleep issues if you have all the stuff you decrease BD NF which is a substance that cleans up your brain and what he saying it was it's a very interesting podcast is basically everything you said you need to fix your gut you need to sleep well need to protect your brain all those things that we always talk about because this is the burden it's going to happen if you don't do those things properly and he was talk about doing a like this cog not Skippy the colonoscopy to do a Cognos copy periodically you go in and you check different markers insulin levels hemoglobin A-1 C and things like that in a bunch of others but I thought it was just an interesting term I think your parents called us to be like that we don't think any of going in and having a colonoscopy because now it's normal for everybody at one time it wasn't we should be doing Cognos could be in trying to alter the course what interesting well it's a really cool idea especially if you could tie it back to what the cause was what causation was met with the that's exactly was talking about unfortunately you have pain I give you opioids let's go back to the root why do you have the pain man there is the music hey that was at its first hour of getting project episode 12 in the books like us and share on iTunes and on YouTube we will be back in just a moment this is the only 24 hour take anywhere platforms dedicated for food and fun we're spooning our town hall.com, there are downed trees and power lines homes and businesses damaged or destroyed after tornadoes right parts of Missouri overnight they capital Jefferson City was hard-hit often Thompson lives there and says his apartment complex suffered heavy damage through formal offices all look over the one billing that may save one story and I willingness to story this one going one story now my building my room every PC rocket windows blown out a tornado killed three people in Golden city Missouri now flooding is a major concern severe thunderstorms moving across parts of Oklahoma Missouri in Kansas John Walker Lind has been released from a federal prison in Indiana California man spent 17 years behind bars or providing support to the Taliban in Afghanistan he was captured on a battlefield there in late 2001 there is a legislative standoff in Washington Pres. Trump says it will not end until House Democrats stop investigating him any hope that the president and congressional Democrats could work together on infrastructure has been shot down and Mr. Trump says ongoing house investigations are to blame you can't do it under these circumstances because the investigations phony and is refusing to negotiate policy until they're over and the presidents also upset that the speaker has accused him of engaging in a cover-up Greg Claxton the White House lawmakers in New York have given final approval to a bill it would allow president from state tax returns to be released to congressional committees that have so far been barred from getting the president's federal returns Josh sharply lower on Wall Street now down about 370 points loss of more than 1% the S&P is off 35 points Marley stories said town hall.com are you tired of high cable TV rates sign up for dish today and get a $500 bonus offer while supplies last loss locking your price for two years guaranteed call American dish you are dish authorized retailer now 800-570-6630 800-570-6630 – 800-570-6630 offers required by vocation 20 from early termination fee at the auto face friction supply call for details have you done it yet you catch a glimpse of yourself in the mirror I'm I'm one of those people you don't want to see naked I yeah most of us but I mean you look and you're going to die I don't get whatever all its horrible stock Townsend and Brad Staggs to tell you about a different way to shed those pounds this is brand-new technically been around for a couple years or so it was based on research from the University of California that said there is a molecule called OEA that's found naturally in your body produces it in the Mediterranean diet that when taken in concentrated amounts it will actually make you feel fuller and boost your metabolism I lost about 10 pounds so far is an amazing Valley school company said we can take this to market to make this great product will help you it's called read you zone our IDU zone.com our IDU zone.com Brad's workers were comrades work for me countless other people go to read you zone.com and try today you're gonna love it read you zone.com remember that our IDU zone.com it looks like you're losing I am I losing weight I am losing my lost about 10 pounds how are you doing it funny name but I done it with review zone RAD use zone.com and the stuff works it's you get it all that the molecule this and that found in that all I can tell you is it it so it makes you feel full and he keeps your mind off of wanting to overeat and also boost your metabolism as your done and more guide try it today it's gonna work for you like his work for Brad and countless other people read you zone.com are IDUs zone.com all right we are now and to our number two of yet checked project so number 12 with your host Ken Brown I'm Eric Rager check egos at the door because nothing is off the table so we have a study that we promise are going to get to but I've got to remind everyone to like us on iTunes go to iTunes get check project is search for gut check project you'll find is there like us to take a screenshot email is that you did it@gutcheckproject.com through connect and once you do that you'll be entered into the contest where you will receive outrun teal and your preferred flavor of KB MD CBD and that we should call it the signature pack on the KPMG store that's that offers what I'm skewed hunt is more than $100 value as I stumble over my words easy for me to say goodness yes value over $100 and just go to gut check project.com hit us on connect tell us that use that you subscribe to to get your project on iTunes and you will be entered so also you want to just when is Dr. Brown puts it when no matter what go to love my tummy.com/Simoni get yourself a discount on the world's only NSF certified over-the-counter solution for bloating and abdominal discomfort packed with polyphenols but a lot of polyphenols in this box – especially one in your hand but I'll try and teal developed by a board-certified gastroenterologist who happens to be sitting across the table from me after until is NSF certified for sports or if you're an athlete and you need your daily polyphenols go to love my tummy.com/spoony and get your daily polyphenols to help with recovery and athletic performance band what is that dead the doctors name from the exit University about about well but well yeah she's got some excellent information on how Pro anthocyanins which of the polyphenols inside about trying to heal actually benefit athletes when taken at thousand milligrams a day so give the doctor it's basically four capsules about trying to predict correct yeah it's so for capsules due to the polyphenols as the antioxidant component I have a new article that were to talk about at some point where it actually looks because there's some confusion about I did talk to a PhD who is doing some research and said oh we no longer think polyphenols because of the pro-oxidant component to it meaning oh does it actually create a lobed of information as it turns out a new article came out the polyphenols are fasting mimetic molecule meaning you get the same effect as fasting which means you to have my toffee G autophagy cell renewal because the six cells go away that's the pro-oxidative effect but the antioxidative ones so once again it comes back mother nature just seems to do better it's really hard to take a concept in a petri dish and reproduced with humans yeah definitely so I'll try and he'll get some love my tummy.com/spoony so Dr. brass P00 and one save everybody's a winner yes so I don't run you were going two to address a PTSD article and I don't want to get cut short here so because we did last half hour ago and that you can stearate will I was little there but first I wanted to this is dangerous this is by no underlings in Chelsea this is a note kind of interesting I want to present a scenario you got me thinking about how you saw that guy in San Antonio with all the keys and he just walked up to the trash cow handout cameraman cameraman and you're trying to do a back story for likewise he otherwise indicates why you will regret it now I doing other things I want to tell you a story and then I want you to tell me the back story okay okay this is an NLP exercise whose Robert Seale Dany Michael Barnhouse stuff yeah signed neurolinguistic programming and what that is certain words or certain sounds are certain memories will create emotions around this time okay I just want to back so I just want to know what's actual happen you sitting there and out of nowhere a woman runs up to another woman and slaps her that's it tell me what happened to me why Tillie what's going on with that scenario well I can't believe you don't remember because the woman that was sitting there had basically commandeered the other woman's vehicle from Walmart and had parked it in the wrong spot and it was totally and the woman came in and did the slapping told her that he I think you forget the you were on a boat in Africa oh that slapping yeah yes that slapping incident yet that was the woman who was supposed to fed the lions but because she didn't the woman he came in and slapped her family was bit by few liens and that she was upset that since the one who just sitting there didn't feed them she basically allowed the lines to go hungry and they went after humans wow that so it's because somebody did not do their job properly and that affected her so she was slapping her out of revenge he has a sad day that everybody was okay but you know it's it was very scary interesting nice boat ride out thinking I would I do remember that so that that is your take if you ask a bunch of people gotten you get all different kinds of sorrows yours interesting with the with the.feeding the lion of the lining to the people that's convinced but yours is a story of basically it's of violence right what really happened is that you are on a boat in Africa a mosquito landed on the cheek and she went over and killed the mosquito because that is a malaria infested area and she saved her life it wasn't a violent act she was actually protecting that woman so there's two things of this number one the neurolinguistic programming your prior history of anything like that filled in the gaps right if you're in that area and you witness that you probably think old the woman will save the woman's life sure because we can't have the mosquitoes passing malaria anyway you told it out I immediately place them into an adversarial role between each other no doubt I was doing a NLP lecture which is with this came up and the guy actually open the lecture with that just I just for listeners I had no idea what he was going to tell me to step down, that you just left field which is all about that leads into something super super cool okay so today the story came out about malaria I and for the first time ever a vaccine is been developed okay so were sitting here were like malaria whatever malaria affects nearly half the world's population and a new vaccine may be able to actually stop us and save millions of lives and malaria is one of the reasons why certain countries can't get out of economic crisis because it kill so many people kill so many kids it's super scary I didn't mean one site and I was thinking about it because the NLP story exactly that with the guy said in the lecture by and then I read this article malaria no like others fits perfect and your data into your hammer man story malaria really is humanity's curse we don't think about it in the US but it kill so many people in fact when you look at the world's dangerous animals like always but homes yes mosquitoes only one yeah mosquito rains me they kill more people because of malaria then every other thing that's out there job and about volunteerism when people go to Africa and they you can take I think it's an antimalarial pill I don't know about it but I know that you basically stock up on it and then you take it and then you go and then one of the most important pieces of equipment is the mosquito nets around where you sleep so that you don't get malaria but before you get really deep in their always wondered of taking care of the few young kiddos who had sickle-cell anemia here stateside and usually not not a good situation and but that being said if sickle cell anemia they think was an adaptation mutation so that humans could survive that's an exposure to malaria epigenetic thing where you're at in the environment your genes turned on so that if if you have sickle cell I wondered is the survival from malaria it does do that offset like if if those same kids were exposed to true malaria with that allow me to have a never and never quite figured out why the adaptation is so beneficial because in most cases not every case but in most cases the lifespan is rather short do you know what is really cool is if you get an international infectious disease doctor start asking questions like that it's really wild especially if they get an epidemiology background as well right so you got an ID that deals with stuff like that and they can explain that's a little bit out of the scope of my medical practice not interesting thought but it's fast and because this up I guess in Afr

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005: What Methane In Cows Can Teach Us About SIBO w/ Dr. Kenneth Brown

Play Episode Listen Later May 9, 2019 25:14

There’s no easy way to say it: Bloating causes more pain and discomfort for people than loose stools or constipation. And in the same vein, it’s more beneficial for our bodies if we treat the root cause of bloating before treating for the symptoms of the colon. Today’s guest, Dr. Kenneth Brown, is a gastroenterologist from Plano, Texas who runs a busy practice where he treats patients suffering with symptoms of bloating and abdominal pain. He has been instrumental in discovering the link between research into methane production in cattle and symptoms of SIBO in humans. Ken has used this information to develop the first all-natural supplement to help treat symptoms of methane production and SIBO. Atrantil comprises only three natural ingredients that work together symbiotically to reduce methane production in the gut. If you’ve been suffering from bloating for only a short while, Atrantil will work a lot quicker than if you’ve been dealing with SIBO symptoms for many years. And many people who have successfully reduced their bloating like to continue taking a maintenance dosage of the supplement. Atrantil is not only beneficial for those suffering from bloating, constipation, diarrhea, and other digestional issues. This supplement can also help people who show signs of gluten intolerance, rosacea, and other skin conditions, as well. In this episode, we talk about what causes bloating and how you can start treating it at home, without any additional supplementation. We also look at why modern antibiotics aren’t always the best option when it comes to treating SIBO. Finally, we compare SIBO to SIFO and discuss the differences between bacterial and fungal overgrowth in the gut. Do you suffer from bloating on a regular or semi-regular basis? How does your diet impact your gut health? What are you doing to combat the symptoms of your SIBO? In This Episode: How the research into reducing methane in cows lead to a breakthrough for SIBO How the 3 ingredients that make up Atrantil work together to reduce methane production Why it depends on how long you’ve had symptoms of SIBO for the Atrantil supplements to start having a positive impact How can Atrantil help treat other symptoms like rosacea and gluten intolerance Why our modern day antibiotics don’t often work against gut bacteria Why you will feel so much better when you treat the bloating before you treat the symptoms of the colon What type of diet will work best to help reduce symptoms of bloating What the difference between SIBO and SIFO is Quotes: “Most of the people [in the clinical trial] started seeing a significant result between 10-20 days.” (7:33) “We do know that if we treat SIBO, a lot of other issues get better.” (12:08) “I think that bloating is probably the single biggest problem that really affects people. They can handle a little of loose stools, they can handle some constipation, but it’s the bloating that really is the disruptor.”(17:02) “I would say that the majority of people that believe they have a Candida problem, it’s probably a bacterial overgrowth and we’ll treat that first. If they don’t respond, then we start thinking, well, maybe there is a small component of this fungus.” (21:18) Links Join the SIBO SOS 2019 Speaker Series Find out more Dr. Kenneth Brown Online Buy Atrantil Online Check out the full episode post here Keep up with everything SIBO SOS™ here Follow Shivan on Facebook | Twitter | Vimeo Join the SIBO SOS™ Facebook Community Get access to the complete SIBO SOS™ course catalog

Rachel Scheer & Dr. Jay Yepuri, MD - Collaboration between Nutrition & GI for health

The Anxiety Coaches Podcast

Play Episode Listen Later May 2, 2019 117:29

Rachel Scheer is a fitness model, BS Nutrition and Dietetics, and Functional Medicine Nutritionist . She has several years of experience directing clients to better whole health, and has personal journey of having to find better gut health. She has long collaborated with physicians to allow her clients a more comprehensive picture of improving and maintaining health. Dr. Jay Yepuri, MD, is a board certified gastroenterologist, the CMO of Riduzone, and has served the gastroenterology community in many capacities including being a former president of the TSGE. Dr. Jay is an ardent patient advocate, and has long worked to improve health and patient outcomes by looking beyond the traditional establishment approach. Both of the guests in this episode have played a critical role in creating the DHAT Health box. (DHAT = Digestive Health Associates of Texas) A vehicle for consumers to get direct advice on home products and supplements that are fully vetted, approved, and shown to deliver health benefits, at a competitive cost delivered monthly.DHAT Boxhttps://dhatbox.comRachelhttps://rachelscheer.comInstagram: @rachelscheer and @rachelscheernutritionFacebook.com/rachelscheernutritionDr. Jay & Riduzonehttps://riduzone.com (DRJAY for 30% off)https://dfwgidoctor.comhttps://www.facebook.com/JayYepuriMD/Instagram @DFW_GI_DocAtrantilhttps://lovemytummy.com/spoonyhttps://gutcheckproject.comProgressive number line number two employee hey Jamie it's me Jimmy this is your daily peptalk I know it's been rough going ever since people found out about your a cappella group met harmony but you will bounce back I mean the guy always helping people find coverage options with the name your price tool it should be you given me the peptalk now get out there get that high note and take Matt harmony all the way to nationals this is sorry the insurance company and affiliate by state law and gentlemen welcome to the gut check project where we all take our egos in the door with your host Dr. Kent Brown MD I am Eric Rager 10 it is episode number nine we think that this is so exciting my lysing cats there's nine it's a great number so it's also number there's a Seinfeld I think it was that no no I know it was a fierce Buehler 19 kind every time I hear the date faded number nine this is so exciting though because were starting a little traction were being get on the message by people this is really fun and I cannot tell you how excited I am about today show today show it we actually have we actually have a real offer we've got viewers who have been watching us weekly and now we have something we can actually give back to them and then well know you're right I'm pretty fired up in fact today's episode is unlike any other we have an offer for everyone here to tell us about that often help us explain it is going to be Rachel Scheer certified sports nutritionist and fitness model as well as Dr. J Dr. J Perry and I he is a course a board-certified guesser neurologist and he happens to serve as the CMO of Rich's own which a lot of our listeners are probably heard us talk about absolutely so this is not so the reason I'm so excited about this just wouldn't be doing offer but more importantly our two guests are actually amazing people so Rachel has this fantastic story she's super smart she's a nutritionist and she's able to stay in incredible shape and she's got help our listeners hopefully look a little bit like her someday so we were just on mojo and I had to laugh that Brad Brad encouraged her that she is off to a good start which was pretty funny yeah and I just hope she can hold together before she got ahead and like like many people that are very passionate about their jobs she has a heroes journey that she's young tells about and choosing to explain how she ended up doing this and you're getting her degree at Baylor and overcoming some obstacles and all of the above which is awesome and so that's gonna be super excited talk to her about that she's a big advocate of I'm trying to my baby that's her and I got to know each other and that she can talk about proper way to eat properly to exercise and it might surprise you because a lot of people are probably being way too restrictive for there being two other trying to do this and that and she's you and explain how look like she does still pretty much what you want sure you get to know her story a bit better it's really cool because she has her own personal journey did that relates to a lot of people the May you may think that people they want to come on and talk about things like that that their story does relate to you that it at the case at all she would just recently spoke at the millionaire mastermind is over 500 people to pay a lot of money to be a mastermind group and they had her as a speaker discussing this and she's really open about that because when you look at somebody that is overcome some struggles you realize hey I can do this and there's people like that out there that have learned how to use nutrition which I consider the foundation of all health because if you have good nutrition you have a healthy.all health begins and ends in the chair and she also collaborates with lots of other gastroenterologist including yourself to help serve the people that you serve and it's it's a great unified front she's a great collaborator in that capacity absolutely and then somebody that I completely respect so that we have on that his name is Dr. J you. He is an influencer in the gastroenterology world definitely she was the former president of the Texas Society of gastrointestinal G.I. TSG whatever that stands for but anyways he was president of that he got a political science degree from Penn University super smart I worked with him for the last 17 years he's an influencer always doing the right thing always looking at things from both a political and a patient centric view how do we do the right thing politically and make sure that the patient gets the best of everything we need more people like him out there talking about laws making sure that patients get access to healthcare and he's also the chief medical officer of the product or trauma ridges on emergent get into that and that's super cool also if you haven't heard of it stay tuned because it is so neat we're going to cover so much ground to the front so excited I respect both our guests so much and Anna learned a ton every sewer guest we have had I've learned a lot and that's one of the reasons why we do the show edit without question more thing to add to Jay I like to say that I've doing anesthesia I've gotten to work with a lot of different positions all different kinds of capacities but the people that often times stick out are those that you can tell are altruistic and function as real patient advocates has deftly Dr. J he's been that way since the day that I don't and it's it's no wonder why it's put him into the position that he's in now the cool thing is is that either one of these guests could easily get deftly have either one of them on specifically to talk about what all of their interest are just by themselves but they join together because they actually want to talk about this offer that's coming up later absolutely Emmy is more likely will have each one of these guests back on to give them a full hour and have to say whatever on their mind but today we have such a big offer that we believe it to really important people should announce it with us sure without question real quick paying the bills don't forget that if you ever suffer from bloating go to love my tummy.com/spoony that's love my Tommy.com/spoony use the code spoony it's also printed on that landing page whenever you get there and does save some money on the world's only NSF certified for sport product for IBS symptoms and bloating and if you're wondering what NSF is well Rachel can explain yeah she might just bill a bit familiar with it without being in sports nutrition and death course to all of the people that are just clever wondering really good sign that one of the things that I have been told by I was message said that so whenever you talk about the landing page people did not realize how much money they can save when the putting that code spoony so not only do you go there and get it but you're gonna save a lot of money was pretty surly listening use that code use it as it saves money definitely all a lot of money that's right and just to follow after that train of thought there Oya this last week and received lots of email keep them coming I appreciate all of the comments we had last week of Chris being on episode number eight Christmas song course was the market expert for him but I'm still getting requests for information on how to connect with that James Carroll and of course how do I find Dr. Wade McKenna if you want to know anything about stem cells go back to that episode so much so that he was spotted on our episode by someone making a ducky series about stem cells and now Dr. Wade McInnes can be featured oh that's awesome that crazy man one thing I learned from that night I just said I respect him as a doctor that stood by his guns and realize that he developed this get a patent on something church and just to reiterate that a better thing came out anyway you better come and use you even though my names on this thing that is amazing to me that you shows pure patient advocacy so it's hard work for me is that it looked a lot easier my brain but yeah that's right I think that the just blown my mind with at the infancy of where stem cell is same thing with all these other topics that were really try to tackle here and show you will try and bring a little knowledge differently so if if you want to connect with the show to ask more questions about Dr. Wayne McKenna James Carroll Joy Beckerman Chrissy song anybody we had in the show Sean Brian's please go to gut check project.com and then you will find the connect tab of the top Stratus an email at any point in time and if you like to show all we ask that you do is subscribe and like it and share it with different absolutely were gaining some traction you see today that these Rachel has acute social media following go ahead and check out her Instagram page it's it Angel at Rachel Scheer nutrition register nutrition correct register.com they all pretty much leave the same place you can find right and that's our ACH yell SCh ER and of course like always will: include all links about our guests and the offer in the show notes you can always find us at YouTube channel gut check project and on iTunes search.check project so absolutely now to move into the little personal stuff like we normally do and you hit some KB MD corner news so that Ken is going on I got an interesting week I just came back from Newark New Jersey right where I was part of filming our national commercial for trying to nine are going to launch a national campaign on TV that's always fun to go there and see a totally different industry and realize what's happening and I guess the the take away it was good it went really well is really fun when I was doing my makeup I had to laugh because I was this the makeup artist had all her material out there and of course as a guest neurologist one thing I noticed Miller's tons of things was a tube of Preparation H grab that and I said you know I can help you with this issue like she is and how it I my casserole dishes like oh my gosh no use of her eyes I put another piece of the bag felt like saying if you preparation H layout picture hemorrhoids said that she's fine pretty hard to explain them away so I did that and the kids the usual thing would go to my daughter Carl in theater is their learning about wicked so now she wants you to New York watch with good and will probably maybe consider going in August when that superhot wants the U.S. Open also I don't know but I'm being coerced into going to watch wicked in New York and my son just came back from Florida where he played in IGF which is the next level XVIII and under kind of thing you heavily second round upbeat by the 70th right player in the world did it proudly played well and the guy that did it pulled him aside and kinda coach Leftwich which I think is the coolest eyes and said you're brewing up and comers is awesome work on this work on this hidden feedback he gave them feedback this is this is this what I did when you did this so yeah and that's so was worth the trip to Lucas he lost second-round beloved so what's wrong with your family the boys are basically just attacking the hoop this said this, we can they have a quick tournament they both played over the weekend they they play dad Monday and that's that seems to be the agenda they did go and see the latest not this is how little I know about superheroes I know that there is a big blockbuster superhero movie that just came out and told Sue spoiler alert this for me I wouldn't do it because I don't even know the name of it as they both my girl you know that that's when the running joke is that don't do any spoiler alerts everybody it's all over read it I don't know you don't have to do that I don't have your luck you do a starless vision arguing for now absolutely not and wife is doing great she's really busy this weekend with a bunch of the local activities she's heavily involved with that and then not getting run with you actually on a quick business trip at Arizona separate in the transit the week for me yeah we one quick shout out to a friend of mine and a colleague Dr. Stuart Ackerman he's a part reminder to check them out he's a specialist in the pancreas issues biliary US ERCP that kind of thing but he sent me a link to somebody that we both really like it's little Dickie yeah remember the wrapper little Dickie just came out with an earth video was really cool was he sent me a follow-up video on YouTube where he talks about how the way that we are producing our food is affecting the environment what I loved about it through some of the cows producing methane and of course that's right in our wheelhouse until yeah so you don't methane what if your bacteria grow merchant you're going to get very bloated and when that happens it can affect you know we always talk about our demographic and our avatar when we talk about marketing you really need to dial it in and I was messaged by half port Bjorn soon he plays the mountain from Game of thrones and Magis von Magnuson they have me that heavy letter from ESPN ESPN strongman yeah and they said you know we get bloated also and you're ignoring our demographic what yeah and so I spoke with you know I spoke with our team at the altar until I said were completely ignoring a group of people here and so were you got a new SKU for the mountain of game of thrones and Magnus Vaughn Magnuson fields take over the microsecond down I will go ahead and show you this is going to narrate what reductions doing okay so he stepping away and I get out of do this in golf voice or not you listening to I tend you can see the visual who he's opening up backhoe he's training down like you got an atlas down all my goodness there is a gigantic take green box marked just like the familiar Arbitron teal box while yeah so this is our newest view is trying to yield for strongmen it is a it is 40 kg look like a like a month on your back will I can tweet it I'm faking it right now all intentions even the later nature calls on that inflammatory response so I know this is not a strong man I know they did not actually message me this is actually a gift for episode number nine from our CEO Chuck Scott also super cool nice it looks it's an exact replica of the little one originally this guy right here at all times because I'll try until we can fix people we help with their bloating even strongmen but they don't have to take the big box was nice in the coal that was such a cool gesture and supernatant that's you know something that we get the word out for international commercial now yeah like that and I just got is the CEO KBS research the parent company of trying to also add nice work. There Chuck I do notice though can hear the bottom it says I 90 capsules just like the yeah like the regular size yes so in the also says to 75 mg just like the regular size are you there must be a lot of empty space in these capsules well knowing that we were initially making this for strongmen how you know each capsules about 2 inches long and filled with lead social to really weigh it down okay since no one can swallow so if you if you ordered the large volume here Voltron tales going to cost you a lot of shipping and you will not be will go through metal detector and lead poisoning social just just order the smile you have a bigger one here for you like I had to laugh Chuck Scott just messaged us and said oh my gosh you had me going I thought you were seriously well yeah that's what you I like that know that's that's awesome I think that is so cool and you don't mean that's what were trying to do as a company were trying to sponsor spoony radio care so the alternate what you brought up Morse code last weekend and bid chow down and there's water you chow down his restaurant on his lot really really cool shows and of course we got our we got a man Patrick chef Patrick is yet a show so gently awesome well once you hit up the corner and let us know what's on the other research page for this week so basic what we always like to try and do is talk about a little bit of science here, try get that this really quick and it's gonna seem like a lot but I will come full circle and explain it at the variant and the reason I'm doing this is because our guest Dr. J Perry happens to be an expert on one of these things right on okay and what's silent here that by so I'm a big fan of the PhD name Michelle Ross meeting she wrote a book called vitamin weed and I think it's one of the more comprehensive molecular books that I have read and she covers a lot of ground here one of the things that we always have is the end of cannabinoid system we all have it just as important as the gastrointestinal system all those everywhere in the body if you think about what it really does is it links the neurologic system and the immune system so it really ties those two together so it's extremely important for a lot of different things the purpose of this is actually like a traffic cop and control the amount of nerve and about nerve activity going back and forth so just try to make sure that everything works well which is why work so well in anxiety and autoimmune diseases so the end of cannabinoid system helps deal with physical and emotional stress so now what is a cannabinoid basically you can take a cannabinoid final cannabinoid you can synthetically make one drug not a fan of those sure and your body makes him what were to talk about are the cannabinoids that your body makes okay so it's it gets into a little bit deep stuff but the most prominent thing that I want you to keep in mind is that there's two and or cannabinoids that everyone always talks about Ananda mind into a Jew when record our mothers because those are the ones ever talks about and they deserve their own hour each what I want to talk about our the atypical ones and then this actually explains why a full-spectrum Fido cannabinoid like the KB MD brand right here powered by Alexa no actually works a lot of different ways and that's one of the reasons why I believe that the full spectrum will always outperform a synthetic cannabinoid or drug cannabinoid buds naturally powered by numbing it's basically a doorway that nature intended it to happen so course is usually better yeah so even if you know quite a bit about CBD so if we get our people out there like I know all about it yeah and about to Aegean and Ananda might listen up because this is a little different so I want to talk about four different Endo cannabinoids one of him is called PEA P like a grantee that she stands for and Palma told EO then Nola mean originally discovered an egg yolk ticket of this is that it has been shown to have a potent anti-inflammatory activity and has a role in preventing neuropathic and chronic pain while one of the problems is that alcohol decreases PTA okay so keep that in mind because a lot of people trying your luck you will develop alcoholism or opiate abuse because of chronic pain a full spectrum vital cannabinoid has PEA in it so it acts in synergy with the other main one to AG and Amana mind born entourage effect when you help those out and it inhibits an enzyme that breaks it down called F88H so the enzyme FAA age breaks down your endogenous under cannabinoids So that's one I hope this works on inflammation and chronic pain then there's a supercool one called OE a and only old less than Nola mean OEA let's unfamiliar does sound familiar it's in this bottle and holding my hand from ridges on exactly what they have and here's the key ingredient's riches on one of the sponsors of mojo and spoony chief medical officer Dr. J Perry coming on the show today want to let him talk about why they put a concentrate of OEA in a bottle want to tell you is that your body makes some OEA and it's been shown to do some pretty cool things this is produced naturally in the small intestine from fatty acids and the major target is another cannabinoid receptor called P part alpha easy for you to say I know that's a proliferator activated receptor alpha now that is something that I would be doing quite a bit writing on because people are alphas or NP pile for people or gamma our associate with inflammatory processes in ulcerative colitis also the proctitis wow so I'm in a working to be publishing some really geeky cool stuff but I just want to throw this out there really quick that OEA has been shown to be good for brain health and believe it or not it's actually been shown to increase memories in rodents and it doesn't pretty cool things for weight loss but I believe that the doctor your Perry later because that's where most of the science is been done but they have shown that this molecule actually helps the brain and memory it is so wild I mean basically were talking about natural compounds available to us to make us feel better and stopping inflammation in it wild bit how many times over the last decade now have you encountered this this this crossroads of stop inflammation help your neurotic neurologic system help the way that you think helped ladies sleep I mean there's a lot of other connectivity there it just keeps going back to all health begins and ends got exactly in his illegal had explained Dr. Pursley go ahead and explain about how rigid zone gets converted in the got into this potent molecule that works in his own, different science but I did not know it actually helped with memory in the brain as well so it decreases the inflammatory response that awesome number three something lumpy will heard of DH eat a dry and dull Xhosa hex being all teeth and no new beauty mean hard that's likely make acronyms for all these no real word it's really hard to Google now this is made from the fatty acid DHA which is fish oil omega-3 DHEA has been shown to reduce inflammatory gene expression there's that word again inflammatory your body will naturally produce the hormone DHA in the adrenal gland in turn DHEA helps produce other hormones like testosterone and estrogen Rachel's really get into that some adrenal fatigue some adrenal lagging this is the kind of thing that nutritionist work on and then the last one here is not an ADA Nora can O'Donnell dopamine it's not really clear how it's made but it is made in the brain in the hippocampus region it relieves pain increases sleepiness and decreases body temperature while relaxing your muscles okay so will all those neck all those acronyms those I brought this up is because when I give CBD FIFO final cannabinoid to my patients I get all different kinds responses now it makes sense you could be deficient in one of these so the short review was necessary because patients may tell me that they sleep better with her nerve pain is better now I can say oh if you have insomnia maybe your not all levels are low or that needs be increased or if your memory is bad maybe you need more OTA oh your sex drive is down how about increasing that DHEA in other words this is why a full spectrum high-quality CBD can be so effective it's filled with all these are the benefits that nobody ever talks about how they are talks about but you know ever but a lot of different people have made these connections if you want to be healthier if you want to sleep better if you want to feel they all go together you simply have to eat better so that you can sleep better to sleep better she can think better yet the sleep better so you can repair your body it's it's amazing we've only got every half-hour or so Dragon Go! I know but everyone to you now because we have our two guests on and limits I want you to watch this live trust me on this it is good to be a cool shoulder to cover a lot of stuff and it's the offer that's most important that he has said Rachel Scheer is coming on with Dr. JJ Perry to basically deliver some great news that is happening here has been announced anywhere else and trust me you don't want to miss it subscribe and share gut check project iTunes and YouTube seamen got an old car you can donate it whether it's running or not to the United breast cancer foundation and save a life they'll even come and pick it up for free the United breast cancer foundation has saved hundreds of women's lives through their free or low-cost breast screening exams but now they need your help the United breast cancer foundation wants to save more lives through early detection by offering women free or low-cost breast screening exams in donating your old car SUV or truck whether it's running or not helps pay for them plus you get a charitable tax deduction help the United breast cancer foundation save lives by donating your old car SUV or truck call now for free pickup 800-245-0823 800-245-0823 800-245-0823 call right now that number again is 800-245-0823 it looks like you're losing I am I losing weight I am losing my lost about 10 pounds how are you doing it funny name but I've done it with review zone RAD use zone.com and the stuff works it's unique it and all that the molecule Bissonnette found in that I can tell you is it it's it makes you feel full and keep your mind off of wanting to overeat and also boost your metabolism if you're done and more guy try it today it's gonna work for you like his work for Brad and countless other people read you zone.com are IDUs zone.com FastTrack student loans can get your student loans out of the vault stop any wage garnishments stop collection calls and stop seizure of your tax refund give yourself a break to stop the stress and get your student loan payments down to as little as $25 a month based on what you can afford to pay 800-709-4395 800-709-4395 800-709-4395 800-709-4395 five so here we are back where set up where you have Rachel cheer Rachel give us a little wave over here Dr. January's on his way to show Patrick over there messing with our sign so that's that should be resolved shortly and Dr. Jacob Perry is entering the room welcome Dr. Jay running a little behind his usual not a problem so Hayward while getting started here on this the second half hour being spent on what is on the second half hour want to welcome have your Mike oh I got him holding exam. This one takes it so we believe we are we on episode 99 episode 90 so were going to fix a couple things and elect the real host Dr. Kent Brown handle the set up and I'll be back in a moment so for the record is the first time we've attempted to guess at the same time and we are working the kinks out with one of the mice it isn't working but we have the two most important people in the room here Rachel why don't you go ahead and tell us who you are my name is Rachel Sharon and functional testing test here in the Dallas-Fort Worth area is not our idea by building and can accomplish it is that how you met Dr. Jerry Perry on the on the fitness model circuit precedent lot I try try to keep that on little bit second second CV if you so knowing what no one wants to see that the ups Michael Dr. J very quick bio here what's going on with you where you come from who are you for our listeners who might well so native of Louisville Kentucky missing home this weekend because the Kentucky Derby try to make it up as often as I can but been down here in Texas 18 years and haven't found a reason to leave yet so been fortunate to be your partner in our in our larger group practice for many years now and and enjoying working with you in a lot of different different different ways we have so far so absolutely so Rachel we went on mojo earlier for little bit we covered a lot of ground in just a very short period of time but I think one of the cool things is that you just recently gave a lecture at the millionaire mastermind club correct mastermind million-dollar mastermind tells about that and why were you chosen to do this that's a huge honor by writing something down at the heart grow closer and basically he brought on different influential people Oliver United States entrepreneurs have created their own business and any talking about sale of business strategies that they brought me on as a nutritionist very different type of form that my business name brand and being able to share my story nutrition is very important as we now for overall health think about it from a business standpoint I can again have your point is why nutrition is essential to building a business from an entrepreneur print right why how did you become so passionate about this and getting the word out about nutrition now nutrition is something that always been important to me and I suffered from mental illness speaking or lapping in very unhealthy environments my mom was very absent for most my child had an very unhealthy growing up they prompted me to want to get into nutrition and extending into Shanghai Weightlifting along the lines on background that growing up base nutrition and always doing the right thing for family and along with my right to allot and different health issues related to later on sale I really have to make a lot of different changes in my diet to really think out but worked slowly back up and do you think that your you said you were not making healthy choices because you were trying to become stage ready you are starting to get a whole fitness modeling tell me about the add big mythic between felid and health that we live in a world where everything is the last thing on building muscle and makes me look healthy from outside you can lose weight eating teepees the defendant don't print any packet to be healthy now and I think a lot of them might have me think carbohydrate is carbohydrate and fat really is not the case any nutrition Avenue the carbohydrate is a need to stand on bath a big misconception concurrent with my American Standard something one of the cool things is that you become very best about it I think his attrition is turning into a business as awesome as gastroenterologist J I did not get that much training nutrition during my fellowship did you well it's a great point you bring up Canon and listening to Rachel talk kind of got those wheels turning in my brain and to echoed the point you just made it's important we get no training in that regard I mean that traditional pathways all based on pharmacology and medications and treatments and interventions and procedures that we do but these kinda more basic fundamental building blocks mean it's cliché but you are what you eat breakfast by cringing when she hears me say that but I think it it it really resonates and rings true in the current era it's been it's not something that we patient always talk to us about it but is something we have to defer to someone like Rachel who is an expert because we don't have that training unfortunately you know it's not something that you and I talked about were when I sit there and I actually tell my patients point blank some of the best knowledgeable people are fitness people bodybuilders an extreme sports like triathletes because they have to take it to the level where they are so dialed in and I learned a lot I learned a lot from my other colleagues have done that there are people out there I got a chiropractor friend of mine that we brought up before his name is Dr. Ron try to bend us in the Plano area delete triathlete is the first guy that's talking about nutrition and whole foods and things like that and so what you did is you jumped into this started getting into the body changing type of mind came from a background of it sound like a very difficult childhood and you want to control your life and then you did something and you paid a bit of a price that we deal with patients all the time the commensal tongue what happened after that cell I Carolina stress dietary strength physical strength training very hard on a lot of mental stress this volunteer instructor is one mean initiators and Ellen and over the course of training really hard and really trying to down I did not hear gastrointestinal issues in the process where basically I remember I couldn't eat anything anymore without being severely distended a lot of chronic bloating brain side and I mean I was miserable and even now from the outside and looked healthy I like definitely not healthy Ceylon really prompted my change in nutrition and going more into that function functional medicine and nutrition that is what is the most common patient the senior officer I mean you can as you know we see the full variety of digestive and liver issues but I would say is not a day that goes by that a patient doesn't come in with some of the issues that that that that Rachel is described that we don't have a blood test for necessarily that we don't have a an x-ray to do that we don't have a procedure that we can do to assess but it's it's all part of being thoughtful careful listening taking a good history as we call it and and part of that now as as Rachel brought to light is understanding what our patients are eating with the putting in their bodies that can help contribute to the symptoms this is a new developing burgeoning area of inquiry research and in clinical endeavor into exciting meeting to see what's coming out this I think it's kind of a it's funny because even somebody like myself who considers myself more functional casserole just I do podcasts all outgoing people shows and I'm unfortunately I want to try everything to see if there's something that's there so that I can offer to my patients so I will try reading first and then do it and we have a mutual friend Kevin Wilson who is actually my primary care Dr. and I had to laugh because I got blood work done and he called me up and is like to what is going on like everything I'm doing everything is accordingly much this supplement the summer I can try to figure out where I overshot it and my bloodwork got really screwed up liver test one my cholesterol got all messed up I went okay can't do everything all at once and what I did the real big mistake that I did as I played partial Kito I did dirty Q Roseland Chito you know what I want to sort of cheated what I wanted not the exact worst thing that you could do so even when you're living it you don't realize that you're doing some of these things so like you're living in your eating bad so how did you end up correcting all of that well I went from a lot of different doctors to doctor that blew my mind right now I ever talked about he never went back to when I was putting into my body endoscopy colonoscopy CT scan and MRI and everything analysis got stopped at the label of irritable bowel thing on which to diagnosis at all like a stinking nice next contend that any biofuel into depression throughout this process depressed and I was offered laxity is not offering that many if I think I mean how getting diagnostic at one point I had misdiagnoses and always miss is getting medication and medication anyone really went on to write that will cause what is causing this in the first place I went to see you and I think you are one of the first doctors actually saw something that a lot of doctors hypermobility going on here can't cannot let one and she is going to the Mayo Clinic and found that actually had a genetic defect. Thanks Thomas Ingram is about to sail could have been added by weightlifting and again it still came back to and once I really looked at my limiting a lot of different taste in that standard American diet really started to make progress in fevers don't think you really feel better overall J you and I've had discussions about this your thought leader in the industry I'm in your recognize on a national stage and both of us wish we weren't so busy I mean if you were were really too busy and there's something going on here where people are getting sicker it really is an epidemic I mean I think you know we see these folks every day and and again where we continue to struggle with a lack of I guess where all creatures of habit we want to be able to offer the test want to be able to offer the treatment we want to be able to offer a cure that these are complex issues and in the very individualized I think the one thing that both of us have realized over time is one of a person one patient is any different from another patient and and it's not some boilerplate it's not in a page 32 the textbook it's can be very individual approach patient by patient but you're right I mean these patients are filling our offices were happy to help him but we have many more resources and we mean we need needs things up and go back to be able to offer patients think that every time the I did a patient where I struggle we figure something out I become better I learn and I know I've met all of your partners I got my partners and just about everybody I know in our group digestive health Associates of Texas D hat is a very conscientious group this is a smart group like I think we've collected some of the best gastroenterologists in the country in one area and everybody wants people to get better so unfortunately when a patient comes in and we don't you do: EGD when you start thinking outside the box when you start thinking about the functional aspect of it so when you said you are functional nutritionist can you expand on that little bit of function on looking hot now find people going into the doctor and I think I have Andy throw the mind filling in anything really interesting because not just interesting testing that will cause would be there diet their lifestyle that I can exercise and really trying to deal with my nutrition practice I'm looking at real cot why do we have this problem in the first place inlet committee to restore function and it comes back to the lifestyle I die like an exercise in meaning initiators as chronic in today's world I think when I talk to people one of the things I discuss his death rolled as I believe there's three pillars of health one of them is gut health absolutely all hope begins and ends in the gut to use the we are chronically fatigued society and three rain you know I discussed on that article the beginning there about these different final cannabinoids and help the brain help me when you address a patient that has something like this and what is your what is your methodology to try to figure out how you can help this person and I think you're the approach you outlined these three pillars is is is key I think this this concept of sleep hygiene is something that's been under recognized and underappreciated for a long period of time and these are not mutually exclusive pillars right any date they feed into one another that the lack of sleep increases cortisol levels you eat as a result you feed the beast when those cortisol levels are up such a self fulfilling prophecy so I think the those three really do feedback on one another not be too exclusive in any way but I agreement I think again it goes back to this individual approach the patient in and try to understand exactly what that root causes as rituals ELOQUENTLY put on to help that patient yeah I think it's so cool that you chose functional medicine is really cool is that you chose a very Hartfield to maintain as somebody who's always worked out and I'm digging on pushing 50 now and I am trying to work out harder to do it all this other stuff tell me about the lifestyle of somebody that actually gets ready to go on stage well completely different in mind the least of my problems for me in the work that is kind engraved in my routine now I love working out nutrition and I love you now feeling my body appropriately and that the whole mindset of having to get up on stage in preparation in the training of food and take a bath link takes it to a whole never not a level running out for general person if he could just focus on healthy foods and eliminating process and artificial fluid that can really make a huge deal in their health that for someone who is a an Olympic athlete or something like a bodybuilder are trying to get to a certain level things have to be a little bit more now than when it comes to their carbohydrates and fat and protein intake and definitely takes a lot more concentration in a lot more work to really fascinating because I just got in the mail about Glenn Greenfield second revision of his beyond training have you usually with Ruben Greenfield is yet so bad I did his part just been is a former bodybuilder than triathlete and then now he's just a big proponent of his brand is your wrinkled tile KIO and supercool guy but in his book his intro the first chapter is the description of a 50-year-old guy whose tried to maintain his try to be a triathlete and in the process became skinny fat increased distress started having injuries and also the stuff and it just shows that in this desire to maintain health sometimes we miss the big picture they can can hear me oh yeah hey it's Eric I'm all I got here in the garage I was really lonely I run out of did it really wasn't a problem not of had to go outside so you help them Parks and Kari took a wonder I kept trying to I know it's a mystery just to add about talking on then Ben is actually going to come up to demonstrate his audience he actually saw Ben and his helper Angel Keeley's going to come to North Texas so that we can do a colonoscopy on someone who has gone through the quota quotes getting fat and that being basically he him working in nutrition just like Rachel does and then of course Dr. J Perry working in gastroenterology I think that something is really cool by the two people sitting across the table from you is that these are collaborators and they collaborate and they want to do something for their audiences much like what Ben wants to do so why don't we can talk a little bit about what it is that we want to do for the people and then we can really cannot get into that for the next whole hour the absolutely so one of things we talk about here we've got a brilliant guest urologist and a brilliant nutritionist Dr. Jaeger Perry spent a lot of his free time advocating for patients on a political level is a political science degree from Penn University what you choose that by the way science yeah well in a previous life I thought I was good to be a lawyer and and even become a lobbyist spent some time working on Capitol Hill between and after college and I realize overtime that wasn't for me but what I liked about twice I was it it's a field that makes you have to take a lot of information understand it digested no pun intended and and then be able to make arguments from it and it's very much like medicine you got it learn a lot be able to process it be able to assimilate it in bring it back out and order entered into care patients I mean I've from my standpoint's admittedly when you start medicine you work really hard to get them and then you become very selfish as you try to start your practice or try to feed your family good becomes you know this is my this is my dig so I've always watched you from the very beginning always be involved on the political stage always trying spread the message always trying to you been running the ACG practice management thing that I've been part of a couple times the project management group so what what we need is people with a voice that have a stage the to do something like this and then Rachel you got the functional nutrition background so one of the reasons our big offer is that we as a group digestive health Associates realized that our community in the Dallas-Fort Worth Metroplex could use a little assistance could use some knowledge could possibly use some of that it help just in case you're not eating perfect not able to go to whole foods and get the the wild salmon to get your omega-3 used to protect your brain to know all these other things and that's were to get into in the next half hour I don't want to spoil that too much I think it's a really cool thing Eric you want to comment on that no I do think it's a really cool thing there's a lot of challenges that people endure whenever they are going to select supplements and just doing anesthesia both with Dr. Perry Amber Dr. Brown I have personally seen people come through and they'll have a litany of things and then as both of y'all have seen those people leave the clinic whenever y'all done the examination will save habits that they have just isn't going to work for them or I don't know that I can trust the brands if you're spending all this money on so when I saw the two of y'all and the rest of the D had a group begin to work together to say we're going to tackle this issue where we can actually leave the walls of the clinic use some help from a nutritionist just like Rachel and began to find the correct type of supplements that would benefit people and lastly save money it takes the guesswork out of trying to be a good patient and trying to find health something it's really pretty awesome I think one of the cool things is that you're able to follow your patient home we can give some information if somebody follows you an answer which by the way how did you get 260,000 Instagram follows pretty happy what we up to Eric eight or something like that just got number nine Monica Crowley had no idea they were actually growling to be something that made I started it when I got an outstanding tensioning Titanic started posting track and recipes and think that I find to be motivational for myself in a way to hold myself accountable and I really wanted always to help you but I found his passion from the beginning fell over mechanically derailed and banned from each success has nothing to deal about it on fire as I have or about how much money a status value I can bring to others and how many lives that I contact change that's really been important for me having as my foundation I think has allowed me to really grow my following and really create that trust now so I think very much like taking an oath that were going to treat people well you know social media is got to the point where now you're held to a certain obligation. You also have a responsibility to do things correctly people look up and down a lot of information even on social media for example there was the cochair recently in the Dallas-Fort Worth area has led getting out different diet plans and putting herself as a coach and scamming people out of money set itself up to the consumer to do their research and are looking for coaches online and looking to people for advice on sale social media have a huge influence in people do not have to honor that I think you and I were talking about the Netflix special fire were I believe that they are trying to prosecute some of the influencers you write there later using their using their influence for four not good and I think the D had obviously is taking the can the complete opposite approaches they want to guide people that are already turning to them for advice and visa returning patient so obviously you want to be satisfied so I think that your online reputation speaks for itself you have an incredible social media presence on online reputation patients are saying go see Dr. your per it's the same thing you're getting as physicians you are being spoken about in patients trust you and there to tell their mother's sister friend husband wife to go see you and you and obligation to do that also to know sometimes get tough cases well and it's this notes the community right so you is you and Rachel both touched on it's this idea that were being held accountable there's a lot of ways in which were held accountable but I think is that we started to realize you are pioneering the scan but this idea that our patients are starting to look online and an understanding that the doctors that they're seeing the professionals at their seen counselors there seem this is not well understood or well fleshed out sick seven years ago but clearly over the last five years as its gain momentum when we realize this is how our patients are finding us now and it's it's in a word of it's the 21st century word-of-mouth if you will and and and you know I think unfortunately there still a lot of fraud out there but what what hopefully social media online reputation patients being proactive in reviewing doctors and in other providers is the idea that they're going to help people find the right provider for them that's going to help get them where they need to get total in I think that you probably if you put yourself out there so what I do admire about you Rachel is that number one to get up on stage with a little close which is able to do I would have to if I did some sort of stage competition it would be like jumpsuit things are this is why got a bikini And starting again it's a bit better for everybody well you know what I mean I was following you for a long time on Instagram in your bikini competition I been the last follower I have another as long as I could and I appreciate I'm looking right now where is there were some convocations they asked that it was taken down to I think that's one of the requirements of bikini modeling is landscaping and I will leave it at that have nothing to add to that no but I think that's so one of the things that Jay and I have to deal with which sometimes is a very good thing is the negative review and I sometimes it's valid sometimes not very often it'll tell me that if they warned me of something tried to call couldn't get through it's things were always working on in the business aspect that's one person there's probably 20 people and we really do acknowledge that and the person helps me out with that to-Keith Kaiser who a look at these and says okay you're seeing a trend here we need to sit down with the office manager and possibly talk that may be XYZ is broken so we I use these reviews as a way to grow as well not just say okay yeah this is kind of doing well do you ever get any negative things on your Instagram with 259,000 people out there to over 250,000 people and you're gonna get people always have something to say and think it's taking anything else on and course I like to listing any type of feedback that I can take in and prove myself and they also just cannot stay out of that negativity and just focusing on the people who I can actually benefit any and most important to me okay so one of the things review of weird people with income embouchure but my kids don't have phones and I'm 14-year-old a 12-year-old and the reason is because I discovered a YouTube video early on which discussed how there the equivalent of getting lights is a little dopamine release very similar to other things that you can become addicted to and ultimately when you are depleted in dopamine dear Sir or basically when you release dopamine your serotonin goes down so your happiness is serotonin your pleasures dopamine and the phones really can do that because it consumes you and so I let my children decide right now they have chosen to say you know what were just going to cut up avoided that right now which I'm happy about it's I don't know how much longer I can do they all can I hate to cut you off only got about one minute left before have to take our four minute break and I do want to let everyone know that Rachel Scheer and Dr. J Perry will be joining us and then for the next hour but before anybody has to they have to check out and they want to learn more kindling hold that that box of just so people can get a preview organ we talk about the next hour that is the D hatbox and if you want information without any cost to you to be sent to you as soon as it's available go to D hat box.com it's DH ATB OS X.com and then you will be some of the first in the country to be given the opportunity to check out anything more avidly likely to quit so this is we just got to know you guys over this first half-hour now going to get into some super fun stuff like ridges own love this product Jason to get into that about the signs of that were to talk about the box and about different supplements that Rachel likes to use to look this great instantiate so combat for the next half hour or to get into the science part of the refund this is the only 24 hour take anywhere platforms dedicated to food and fun clear spoony is this our Townhall.com, as word Atty. Gen. bar a no-show this morning before the House Judiciary Committee wanted to ask more questions about the molar report are skipping the hearing in a dispute with Democrats over plans to allow committee lawyers to take part of the questioning Georgia Republican Doug Collins reason Belmar is not here today is because the Democrats decided that in morning here today we didn't choose not that Mr. Barcomb he chose Chairman Jerry Nadler we will we cannot permit him anybody ministration to dictate the manner in which we function Nadler adjourning the hearing following the committee will get the answers it needs to conduct oversight capital Hill correspondent Molly Hines German that were threatening to hold borrower in contempt of Congress yesterday the Atty. Gen. spent six hours before the Senate Judiciary Committee one senator raising some serious last test about the origins of the Russia collusion investigator Lindsey Graham says one thing's for sure about the FBI probe into Hillary Clinton's use of a private email server we know that the person in charge of investigating hated traps guys grandma says a blanket over that hatred led to Hillary Clinton being exonerated despite the evidence and that counterintelligence investigation the trap campaigns worn it featured a heading that investigation bowing and text messages to stop trauma from being elected by new report Sen. Michael Bennet of Colorado the latest Democrat to announce he's running for president strategy and plan to announce sooner but pause after being diagnosed with prostate cancer I was cleared with a clean bill of health that gave me a chance to think about whether I really wanted to run or not better tell CBS's morning he decided he does want to Bonnie seeking the party's presidential nomination for 2020 Wall Street the Dow up 15 points the S&P better by five and the NASDAQ composite index 26 points higher more of these stories@townhall.com now you can fly anywhere in the world and paid discount prices on your airline tickets flight today to learn this harassment to read or anywhere else you want to go and pay a lot less guarantee quality international travel department right now low-cost airlines 800-452-1075 800-452-1075 that's 800-452-1075 Dr. Kim Brown here a host of ship project with my cohost Eric Rieger Eric Regency and mojo guys over there and overhears Mooney talk about 20 over bloating I've seen in my practice that I'm trying to is a whole lot more than just a floating product yes it does a whole lot more than just exploding because polyphenols that you find keen on trying to get your exactly right the polyphenols are those molecules we find in the Mediterranean diet it makes vegetables and fruit very colorful polyphenols do these polyphenols can actually stop and nation help you have more energy thinking have you antiaging and polyphenols are great athletes sounds like a hellhole more people than just loading tell me how it is taking out front if you want to go so 2002 capsules three times a day face you aren't bloated and just want to polyphenol intake everyday to three chances are they will go to love my tummies.com/never forgotten apparel is more than just a premium women's and men's clothing line it's a movement to remind us to where American-made and serve those who serve us our heroes never forgotten apparel gives 20% of their total sales to nonprofits that support homeless veterans and off-duty firefighters and 50% to individual veterans and firefighters in need nationwide checkout never forgotten apparel.com use promo code Matt and ATT and get 15% off your purchase oh Mike we are back I was having separation anxiety comes that Levi got stuck at their lady is no way you can count on without you know Senate small it was to properly throw me off I Have a look over there trapped in a glass cage of a move should I want to bring so sorry I hate the fact that now that I'm back there we got more serious that's that's the sad part and knows no laughter all all all the fun stuff is over now hate just a real quick reset we are gotcha project we are on the spinning networks we.com course host several shows you mentioned earlier trays chow down chef Patrick who works is our producer also as a show on their but did you know Dr. J you. If you met him he is considering starting a nether health based show on screen or is that about his former career as a bikini model that's exactly what just happened you know I think that's exactly where came to a failed attempt at bikini modeling and and lack of landscaping that's where that came from I can imagine with the title going to be but as long as main scape works in there it's going to be thinking of you will be it will be a nice hit the panic up of the bills for this next to lowered be sure to check out love my Tommy.com/spooning as lobotomy.com/vignettes where you will find your offer just for listening to spoony and the gut check project to save money on trying to heal and what we hear Dr. J were good people go to learn a little bit more about ridge them so the ease place to go to his riches zone.com are IDU CO and E.com it'll give you it will give folks a good overview of what Richie's own is the science behind it of which there is quite a bit and and how it works and how we like how we how we think people should use it really get the best benefit from perfect and Rachel Scheer make make no bones about it she's got what an incredible following so Rachel what is your favorite way for people to connect with you as well I can connect with me like it's pretty simple lights at Rachel RA HDL and my last name Scheer each EEI canopy where the majority of my social network is to be found my website which is again just 9% nice Rachel Scheer.com Rachel Sherry.com well let's not KISS alright so let's not lose our momentum on what were talking about because when I get here before I had the microphone working again is that we talk a lot about synergy collaboration and it always comes with the right person in mind which is to benefit the patient before you joined us earlier J I can remember that you always know your colleagues that our patient centric or patient advocates and I think that's a key reason on why you were chosen to be the CML why you've never turned away from research and why your patients I've seen firsthand don't just want to be trusting their health decisions with you they like coming to see so knowing they were putting the patient first what it rejected take what did it what it is they were doing is a collaborative to put something together like the hatbox okay so we try to get into a little bit and lost all but the reality is were doing something which is actually incredible very innovative were to be the first large single specialty group to put together health in a box we want to put health in your hands and nothing of your slogan here so the hat is arranging a program where we can put the holes were many Americans lack because of nutrition we can help them out Rachel and I were just talking about this Rachel like for instance when you see somebody what are some of the common supplements that you like to have your clients on that I think there are four essential supplement everyone should be on the first to be a high-quality monk like to say that we can get all of the nutritional needs from the food that were eating back just Arabian American band standardized and fast is not really reality standing on a high quality multivitamin to prevent any type of nutritional deficiencies on this icon would be a good probiotic game going back to got to be the foundation for how promoting a good healthy got my car bran on the third one would be a vitamin D some most the population is deficient in vitamin D and vitamin D became to get fromsale especially here in Texas and because it's hotter now that I'm very much and just in general and a lot of micronutrients testing in the majority of my clients come back with a deficiency in vitamin D then the fourth amendment be in omega-3 fish oil saddle again going back to standard American diet we get a lot more on Bacchus Texas which are pro-inflammatory and instantly need to counter act by adding in more on the three check enemy anti-inflammatory said that for that I think everyone ought to be and it's going to be a good multivitamin probiotic vitamin D and omega-3 fish oil so hearing that list Dr. Brown or Dr. Perry what were some of the pitfalls that the patient to come into both of your practices what what is it that someone comes in with a Rachel hit the nail on the head will get to it in moment but whenever she said hi quality probiotic there is tons of bacteria sources out there that some you may say is beneficial you say that you said it what you think when someone is watching some random probiotic and any notes expensive it's a great questionnaire and the issue is so can I see this every day in the office is some will come in and and it's this it's a typical scene they'll be sitting there and then on the exam table to put out the bottles of snuff caretaking and one by one the go when you think about this what you think about this what you think about this and most the time and and can may have the same shirts I have to say I don't know because these things have not been vetted wheat we don't know and I don't know enough about them to recommend one or another and I will generally say that you know in general I think this is probably safe to use I don't know of any downside but I can't 100% recommend or give a stamp of approval to something because it's not something I've vetted that I know enough about that did to him to be able to give it that enthusiastic or at least thumbs up and that's tough because again you know skin spoke to in the first half we try to establish his rapport with our patients and establish trust in and get that sense if you be a resource for them we can be experts on everything which again is why folks like Rachel are so integral and essential to this process but at the end of the day it's nice to be able to have a way to have a structured way to have a a a supplements and other and other things we can recommend to our folks and that's where I think the box comes so yeah I think that's you know there's a study that came outward look at DNA analysis and that showed almost 79% of the of what is in the bottles not on the label 79% of the products that are on big box shelf so we know that there is a lot of possibly maybe not complete a quality it's being sold out there because it's kind of unregulated and then in your industry when we look at weight loss product sexual enhancement products and I can't know what the other one is almost 40% of those categories had dangerous pharmaceuticals and so in your industry so and I had some patients that are showing up with the liver failure and when you start looking and what what what's going on here is to look at the list you like what what is that ends up being a pro hormone the problem is metabolism the liver and it's creating anyways so it's not only you may be wasting your money but there is a slight possibility that you could actually be harming your body so that's why we came together as a group to say look working to try and that these were you trying find things in a certificate of analysis third-party testing let's see what's there there is some science with that I'm trying to get our group Dr. Harry Sorrel to do this almost every show I call him out because I want to do functional research I want DRI which is digestive research Institute our research division of D hat to look at some of these things would you know really I think it's we can help people out so when somebody holds us out they could say because is no money in doing the research it's not that people don't want it it's just who to pay for that's

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502: Alcohol Stress and Anxiety

Play Episode Listen Later Apr 24, 2019 19:53

♡ SUPPORT THIS PODCAST ♡ In today's episode, Gina discusses the role of alcohol in our experience of anxiety. Alcohol can contribute tremendously to our experience of anxiety and can cause panic attacks. Listen in for advice on how to limit the adverse affects of alcohol on your anxiety! If you suffer from bloating or abdominal discomfort, or suspect you might have symptoms similar to IBS, Atrantil can help. Go to http://www.lovemytummy.com/acp and use code acp for 10% off of your own Atrantil today. To learn more go to: http://www.theanxietycoachespodcast.com Join our Group Coaching Full or Mini Membership Program Learn more about our One-on-One Coaching What is anxiety? Quote: You can’t calm the storm, so stop trying. What you can do is calm yourself. The storm will pass. -Timber Hawkeye

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496: Aromatherapy for Anxiety

The Anxiety Coaches Podcast

Play Episode Listen Later Apr 3, 2019 24:53

In today's episode, Gina shares her knowledge and experience of aromatherapy and essential oils in the context of anxiety. Gina suggests a whole range of oils you can try today and gets specific with five oils. Additionally, Gina describes how you can go about using these oils to help improve your experience today! ACP episode 300 with Aromatherapist Liz Fulcher: http://www.theanxietycoachespodcast.com/episodes/300-aromatherapist-liz-fulchers-anxiety-healing-journey PubMed article: https://www.ncbi.nlm.nih.gov/pubmed/19962288 If you suffer from bloating or abdominal discomfort, or suspect you might have symptoms similar to IBS, Atrantil can help. Go to http://www.lovemytummy.com/acp and use code acp for 10% off of your own Atrantil today. To learn more go to: http://www.theanxietycoachespodcast.com Join our Group Coaching Full or Mini Membership Program Learn more about our One-on-One Coaching What is anxiety? Quote: Healing begins with an aromatic bath and daily massage. — Hippocrates

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Marc Semmelmann - Beating the odds & Surviving cancer, Raquel's Wings for Life

The Anxiety Coaches Podcast

Play Episode Listen Later Mar 28, 2019 117:30

Marc is the ONLY known 5 year survivor of de-differentiated chondrosarcoma. A former D1 football player for the University of Texas, father of 3, and devoted husband learned almost a decade ago that his life was most likely to soon come to a close. With his optimistic and make the most of it attitude, Marc is beyond 9 years of being in remission for a once thought to be incurable condition. Marc has since turned his experience into giving back and has become a private pilot and flies today's cancer sufferers to treatment from North Texas (Decatur), and volunteers his time with many charities including Raquel's Wings For Life. "You're gettin what you're gettin, cuz your givin what your givin..." https://raquelswingsforlife.comhttps://kbmdhealth.comhttps://gutcheckproject.comHey hi Mandy if you don't know me it's probably because I'm not famous but I did start a men's grooming company called Harry's the idea for Harry's came out of a frustrating experience I had buying razor blades most brands were overpriced overdesigned and out of touch and here is our approach is simple here's our secret we make sharp durable blades and sell them at honest prices for as low as two dollars each we care about quality so much that we do some crazy things by world-class German blade factory obsessing over every detail means were confident in offering 100% quality guarantee millions of guys have already made the switch to Harry's so thank you if you're one of them and if you're not we hope you give us a try with the special offer get a Harry starter set with a five blade razor weighted handle shave gel and a travel cover all for just three bucks plus free shipping just go to Harry's.com and enter 5000 at checkout that's Harry's.com code 5000 enjoy and here we are it is episode number four of get Jake project here with Dr. Kenneth Brown I am Eric Rieger again hey doing today I'm doing fantastic episode number Quatro number Quatro that is Spanish for radio no as mentioned before that is Spanish number four yes you are you pretty well versed in Spain Georgia were bilingual home absolutely well do you like to speak Spanish and I'm probably the worst speaker in the house. Let's say okay hey just a quick tough nod off the jump don't forget that today's episode of gut check project is brought to you by John Teal get your own genteel@lovemytummy.com/spooning use code spoony same sums of money so have I been taking some voiceless and also trying to nail that the throne going it's going horrible was that it was that your that you shot that was my best shot is that you back also brought to you by KPMG health brand-new KB TCDD but now you can get to the gut check project.com and be linked directly to the KPMG store and find your own KPMG CBD awesome baby if I gargle with that before trying single improvement it could work well we got a great show today and were going to get to him in just a moment that our guest today is Mark simple minimal touch on that here in just a moment incredible story of survival new lease on life and what he's doing after his battle with cancer but if you been watching get check project for all of the last three weeks you know that dark to our first half-hour is news and notes for gut check project so Dr. Brown what's happening new in the Brown household here since Elisha well in the Brown household what's really exciting is my daughter in her improv it's just theatric class she's a sixth-grader she came home and taught me something really really good that basically whatever you doing improv what you have to do is say yes it's yes and secondly if dues trust third thing is listen and then the fourth thing is make a statement and I heard that no like I need your teacher to come over to KBS headquarters we can work on that as a teambuilding exercise improv exercise to make a team yes and I love that yes and and then I want to trust what's coming next I loved this pretty while the basically an improv class she is learning just great communication skill left I thought we were laughing about it last night so Zachary know to come home with like what you learned today and that's were talking about the really cool thing our house is my son is currently playing in the finals of a really big tennis tournament out in Indian Wells California the Easter bowl to big one so at 11 o'clock our time he will be playing in the finals were very very proud of it in both singles and doubles so the brown households having some good times right now about you well number one shout out to Lucas and Karla those are both the great notes to to be able to carry around the data know that you're proud of both of them for me both of the boys have moved into off-season basketball there really fired up they've been out of basketball all of about 10 days which I think if you shoot who apparently that's way too long so they both get started but something that we did as a family that was a lot of fun just a little week ago I should've mentioned it last week show I'd never done it before my oldest son actually done it before a couple of times and that is we all sat down relaxed and got pedicures and I'm here to tell you that include dad included nice if you haven't done it don't knock it did you try it because I'm going back that fell awesome and now I mean table I got really ticklish feet but I didn't know something learned about myself is that my left foot is more ticklish than my right because as they began to exfoliate the bottom of my foot especially the left side I was crying from laughing so hard as I got in my mouth and of course the other woman doing is looking up and laughing again with everyone else as they exchanged their own jokes in another language I'd alsojust like Spanish and did it at my expense was completely worth it and I will deftly be back so I almost got a pedicure once I know standing out front and I looked at my feet and it remind me of the scene from dumb and dumber with a grinder to toenails a wireless want to do that to anybody to put the clause back in the shoe keep on walking now is he always worried he wanted done it when I reveal like a Frito toenail or anything else like that but I think I walked away as best we can be that had since probably I was a baby's kids really good pedicure now don't even have to ask what you been up to because you and I rush to hang out we were this last weekend he and Emily were business makes a little bit of pleasure yeah and that was in the Utah powder mountain that was awesome incredible skiing lots of powder fantastic so much snow for late March he was beautiful is a great place to go and visit not crowded either now our ski experiences were little bit differently where they were loaded and so to put it in context Eric was like Kelly dropping and taking these tractors up and I actually had escorted down the mountain by two wonderful people Lindsay Vaughn and Susie Chapstick but it was Juliet and Karen are awesome so I survive it was a big thing didn't break anything didn't do anything but the our expenses were totally different you came back just on my couch that was incredible backcountry all powder and I was like oh yeah my little different I had two women sort of guiding me down the mountain the whole way so there's no shame in effect I'll even say whenever you but whenever we yeah got into our skis the first day you had planned on even making a few runs together it was snowing so hard I stopped to buckle up my helmet is safe and I looked up and Ken and the other four people that I was skiing with were gone they probably want you probably want 20 feet away from me but it was a complete wideout for the first what our we skied oh no I Don't I ended up staying in that area and like true why don't I lost everybody like it was you couldn't see your hand in front of you who not only did I not been skiing over 10 years that's not the way to start now and shout out to Blake Kingsbury for finding me he looked like a yeti lost in a snowstorm and that basically was my beacon on the way down I had no idea how to get down but dad know that was that was a great time up it to powder mountain if you like skiing snow skiing deep powder skiing you take yourself a big powder mountain we move on here a little bit to basically the news because yesterday while we were working at the Indocin or you ran up to me you said look at this study this is a little bit more in terms of what we've been talking about bore catalysts and what causes cancer I will let you take it over from there because it's pretty pretty incredible piece but thought it was so it was just published a photo so appropriate to have Mark on the show were duly talking about cancer and surviving cancer well in this just recently published in the Journal of science this month they did a study with a looked at how high fructose corn syrup actually enhances colon cancer in mice so what they did is they took the equivalent of one soda a day and they gave the mice that amount of fructose corn syrup the issue is that they had genetically engineered these mice so that they would get polyps and cancer sure which is funny because you wonder like your to be genetically engineered you never think that your to get that like I'm genetically engineered to be faster genetically engineered bigger stronger than one poor mouse is like on genetically engineered to get cancer and that's how they end up looking at these different studies so what they did as they showed that by giving the high fructose corn syrup dramatically raise the amount of polyps and cancer over 80 times the mice that were not given high fructose corn so this is with an equivalent of one soda one soda a day so it's absolutely incredible because I love your member but a year ago study came out where was looking at how the rate of colon cancer millennial's has been going to share we did a video on that on YouTube or Ricardo was we did the interpretive jujitsu and what it showed is it dealt with the millennial's were getting a higher rate of colon cancer because of obesity they should with these mice they did not become obese they did not develop metabolic syndrome it's strictly due to the fructose and the sugar that they were consumed then they were able to actually show that I take it was fructose the tumor cells love it so much that they could put a radioisotope and they could show that it just got sucked up it turns on certain genes that allows the tumor to go undetected absolutely fascinating because the fructose and that the high fructose corn syrup they believe could be very similar to others like table sugar bottom line is tumors love sugar and this is the first study that's been done were really actually look at that and it's actually fascinated Mileage Is about to Come to Clear My Throat What This Actually Shows Is Now They're Looking at How to Actually Adapt Fasting Plus Ketogenic Diet When You Have Two More Surprises If You Can Give Him Sugar That's Just Going to Absolutely Feed It like Crazy so Fascinating Study Just One Soda a Day Can Do This Just Write down A Few Things Here Because You Said A Lot Of Impressive Information so If We Were to Backtrack and We Can Take Away That Tumor Cells Love Sugar and Live They Love Circulating Glucose That's Going to Be Their Main Desired Use for Energy and That's How They Grow They Don't Have Energy They Can't Grow Something Else That You Said and There Was Was Really Captivating to Me and That Is They Were Able to Take the High Fructose Corn Syrup after Consumed and Basically Activate A Process Where the Body Could Not Detect That They Were Tumors Themselves so Not Only Were They Now Stealing the Energy so They Could Continue to Grow As a Cancer And Develop into a Bigger Tumor Diesel Tumors Now Are Being Able or Allowed to Activate Something Where They Were Basically Incognito Not Being Able to Be Detected by the Mice and Their Immune System Greg Will Exactly Actually Gets into so This Is Where I Start Getting into the Geeky Stuff Little Bit There's an Enzyme Called Keto Hexokinase Which Will Change Fructose into Fructose One Phosphate While That Turns on The Gene in the Tumor to Use the Glucose More so That's What Tells It to Absorb It More so It Actually Little Cascade and They've Actually Shown the Third Trying to Develop Drugs That Actually Block That So There's Ashley Phase 2 Clinical Trials Going on with Her Trends If They Can Block That One Little Enzyme Does That Sure so What Then The Able or Would We Then Be Able to Extrapolate That Maybe the Reason Why Millennial's Are Now Seeing an Increase In Colon Cancer Is Because Generationally Probably If We Were to Back It up Two or Three Generations We've Seen an Increase in Sugar Consumption People Believe That Sugar Is Related to Inflammation That Those Two Things Combined Together Are Now We Are Seeing an Increase in These Types of Cancers They're Being Detected Because When You Consume Any Type of Food He Goes Straight to Your G.I. Tract Would You Say That This Is Somewhat Related or Possibly Related Will That Was the Funny Part Is This Study Gets You Thinking about That Because When They When They Were This Is the First Time That We Have Seen People Having a Higher Incidence of Colon Cancer Than Their Parents Rights for Simon so It Was Speculated over It's Gotta Be Obesity It's Gotta Be the Metabolic Syndrome This Is the First One Would You Look at Something Ago Now Looks like It's the Way That Were Processing Food The High Fructose Corn Syrup Is in Everything Everything but It's Really Concentrated One Can of Soda and so the Consumption of Soda Has Increased since the 80s Significantly So Is It Our Diet That's Doing This Were Trying to Label It with Different Things Owed Sedentary Lifestyle or Possibly It Smoking or Whatever Now Looks like Our Diet Is Really Contributing to the Amount of Cancers That Were Seeing You It's Wild If You Just Look Back I Can Never Looking Back at Pictures of My Dad or My Mom Growing up and What Family Pictures Look like Whenever They Went on Vacation He Would See Everyone and All the Ancillary Players in the Photographs Around And Who They Considered to Be Overweight Back Then In the 50s and 60s and Stephen the 70s And It's Starkly Different Than the Then the Body Type so What People Look like Today and What We Consider Overweight and for Me Personally I Really Don't Even Point It Those People It's Just Our Food Supply Is so Inundated With Lots of Things That You Just Are Unaware Could Possibly Be Contributing to Natalie Being Overweight but Probably the Diseases That Maybe Are Going to Have That You Don't Even Know the Are Manifesting Right Now Unfortunately Possibly Even Colon Cancer for Millennial Becomes Really Kind of the Disheartening That They Are Actually Allowing or They'd the Insurance Companies Are Allowing Us to Screen People at an Earlier Age and They Wouldn't Do It If It Weren't In Balance with with Cost It's Always More Cost-Effective to Catch a Cancer Early Then Late so If They Are Allowing People to Not Have To Wait till 50 To Come in and Just Get Their First Screening and Now They've Lowered It Doubly 4545 and If There's a Family History of Violence Then It's 42 Start to Begin and That Was Not That Way It All 10 Years Ago for Sure It Was an End It's Fascinating Because Here I Am I Just Got This Article Yesterday You and I Were I Was Doing Colonoscopies Yesterday and I Just Started Jumping up and down Because I Realize That When Patients Go into Recovery Most of Them Are Given a Can of Soda after They Get out There Sentiment. To That Right Now Were to Put a Stop Ides I Told All the Nurses Alike No More so to Tour Patients Were Trying to Stop Colon Cancer And Were Causing It by Drinking Minnesota so We Should At Least Lead by Example Would Be Given Patients a Pack of Cigarettes with Her Leaving the Endo Center I Got Admit It Did Nobody in the Hospital System Seems to and from RT Friends at Them so I Bet If You Want to Find the Smoking Dock Just Look for the Respiratory Therapist outside of the Hospital Why That's the Same at Every Single Hospital Ultimate Training Every Hospital Billing I Don't Know Either It It's It's It's Really Kind of Fascinating Hey Before We Might Give Any Other Quick Takeaways from This Particular Study Rotates Just That This One Is Just so Impressive Because It Really Shows That the Way That We May Be Treating Cancers in General Is Wrong so I Talked to Some My Cancer.Friends of My Katie Put People in a Ketogenic Diet Greatly When the Do That No We Don't Do You Ever Use Fasting When Somebody Has Us and We've Discussed before That the Fasting Mimicking Diet Actually Has Been Shown to Improve The Effect of Chemo And Decrease the Amount of Side Effects but That's Still Not Being Implemented so Here Is One Example It Always Starts out As Animal Studies Are Which Is When Humans but I Think That This Is the First Step to Show Hey Proper Treatment of Cancer Is to Starve It Not to Just Dump a Bunch of Sugar on It Which Is What Were Kinda Doing Yeah Isn't It Interesting That Maybe Even When Your Body Is Trying to Recover from an Episode of Cancer Not Just When It's Chemo Induced but When People Begin to Lose Weight Everyone Immediately Becomes Concerned Possibly It's Sometimes the Body Just Knows What He Wants to Do And by Starving These Tumors from the Circulating Glucose Is Its First Mechanism of Defense We've Got to Stop Feeding This Is Base Leads Rogue Cell Or Whatever It Is It Happens to Be Going Out Of Control Yeah… That I Think It's Faster Oh Did You See the Speaking Fascinated to See That That's California Man Was Awarded $80 Million Because He Had 56 Acres That He Was Using Roundup for Decades $80 Million That Is so Wild That It so It's an Incredible That It It Took This Long to Find out about and We Were Spraying It on Everything so We've Got Dividing up the Deck Stacked against You If You Got a Carcinogen on Your Food Chair and Then If You're Going to Take the Corn Fructose Which the Horn Was Sprayed Right Now We've Got a Double Whammy Going on Right There You I Can or When the First Big Move in a Big Push of the Non-GMO Foods This 90 Mode Foods That and I Was Really Rather Ignorant in Terms of What That Actually Meant And It Was Really Easy to Find Detractors from People Who Were Reporting That Movement like All They're Just They're Just Afraid They Were Doing New Technology in Food Development and Etc. so Much More Than That It Comes down to Protecting You and Yourself from Carcinogens Which Can't Taste You Can't Detect You Have No Idea You Have the Healthiest Person in the World Is Exercising Not Smoking Trying to Eat Right And While They Are Eating the Foods That They Trust Such As a Great Piece of Broccoli Vegetable Actually Consuming Glyphosate or Roundup In Their Food and They Get Sick That I Read Another Article Which Showed If You're Exposed to Round up on a Regular Basis You Have over a 41% Chance of Getting Lymphoma Hodgkin's Lymphoma I Don't Know Where They Got That That I Need to Find the Actual Article but in This Particular Study They Were Referencing Ups I Think That Was Used As a Type of Cancer That That Man Got And That's Why He Was Awarded This so Probably for a Follow-Up Episode Because What We Do Here Is Always Try to Speak into the Facts and Know That We Seen the Trend on Various Types of Cancers Including Lymphoma Have Been Increasing I Just Don't Have It on Hand That We Will Tackle That Probably in a Future Episode in Terms of the Non-GMO Versus GMO Roundup Life Estate Is or Has To Be Something to Though Because You Have the Lymphoma Belt in the United States Which Is Nebraska and Iowa Run from Agronomy and That's What University Breast Is so Good at Transplants Because They're One of the First Places to Do the Autologous Bone Rail Transport Because They Were Seen so Much Leukemia and Lymphoma And They Didn't Technically Everyone Said They Couldn't Explain They Didn't Know What It Was But It's the Same Thing Is Whenever They First Figured out the Black Lung Was Kind of the Problem In Minutes It's Really No Different EE No One Created the Industry to Make People Sick but Once People Began to Get Sick It's like What's the Acclamation Here Are Just Kind Crazy Everybody's Getting Sick and You Realize It's a Sit in the Air and You It's It's Really No Different from the Time That You and I Went to Virginia We Worked in the Coal Mine That One Day Yeah with Zoo Lander Haplotype Man Man's Underrated Moving Speaking of Movies Are Yesterday's Sent Me His at His Top Five Movies or Lease That I Reminded Him of That He Wants to Cover Why Does He Send Them to Well He Said to Me Because I Was Just Curious on What He Would like to Talk about Ancillary to Some of His Incredible Story Already but Will Dig in and See How How Well He Actually Knows These Movies Whenever the Last Half Hour Rolls around and See What Mark Knows about His Own His Own Favor. He Descended to Her Did He Fill out Our Gut Check Project Intake Form That's a Good Question so If You Have Somebody July Can Nominate to Be on Our New Show Gut Check Project You Can Visit Us a Gut Check Project.com Go to Connect and since Some of the Way That You Think You Be a Good Fit for Get Your Project to Be Interviewed by Your Very Own Dr. Brown and on That Form of Course We Find out Really Little Bit Everything about Who It Is Going to Have on Show I Do Know It's the It's the Eric and Dr. Ron I'm Here to Just Pull up Movie Lines Occasionally When You Say Things like Black Long That's That's All I Could Think about Them like Julian Yeah Well You Know That That There's Nothing Wrong, Challenge You to Ask the Hard Questions Okay for Any of Our Guests Yeah What You Say That You so We I Think in the Future What We Should Do Is You We Should Have an over under Policy Only Jessica Make Riley Barbara Walters Style Okay Really Did Indeed Make Sense That Something I Met Me Physically or a Mean Just by My Emotional Place Was Funny Because I Actually at the Conference We Are at 01 of the Things Was They Had a Bunch of Movie Directors That Were Actually There They Were Discussing When They Start Doing like Dr. Series Interviews When the Guest Starts Becoming Uncomfortable That's When They Get Their Best Footage and They Really Start Pushing the Boundary Right There so That No Question That Make Sense Though Because It's Gonna Be the Emotion I Said, Raw Motion Is Coming out yet Exactly so If You Can Just Get Everything That's Real Let's Put on Them or Not Billy Gilbert in the Show Here It's Somebody's Review on Some People to like the Movie That Is What It Is but It's Real So before He Finishes the Last Half Hour One of the Main Questions That We Got since Our Last Episode and That We Get A Lot on Polyphenols CBD Really Bob about Your Hobbies but the One That Really Stuck out to Me That We Had Asked I Think Six Different Times Was How Does CBD Address Anxiety and We Don't Have a Whole Lot of Time Right Now but That You Take That You Would've Drilled a Hole Show on That but Basically the Way That I Tell My Patients Is CBD Just Sort of Presses the Reset Button and Puts Everything Back in Balance and If You Think of It Anxiety Is Just an over Firing Nervous like Sensitive Nerve Always Does Is Just Calm It down like a Traffic Cop so That You Just Get All the Anxiety Is Just a Perception of Neurons Firing Right below the Extreme Version Would Be Seizure Early on Just Because Everything down Gets to Go Back to Normal Now so I Kind of Explained It to My Patients Might Just Try It If You Have a Deficiency in Your Endo Cannabinoid System Chances Are You Can Have a Pretty Good Response with Wild Thing Is the Just of Multiple Applications for Utilizing The Indo Cannabinoid System Which Everyone Has In Their Own Body Basically Resetting Just like He Said to Make People Feel Better and There's a Bunch of Different Ways to Make It Happen but Rather Than Make It Sound like a Magic Pill for Everything We Really Want to Break That down and Build Keep Those Questions Coming Dealing with Anxiety Is Something You're Going to Have Someone on a Think in about Six Weeks I Think so You and at That Point Time Will Get a Much Much Much Deeper but Any Other Applications of CBD and Questions like That Combine with Polyphenols… Gasifier Questions Because This Is Holding Figure Who Do Other Episodes Definitely What Is the Old Anybody That Swimming Towards Us Asking a Question We Want to Address It and We Have the Ability to Bring Some Experts in and Were Just Gonna Make Sure That We Do This and Try to You Have Some Fun but Also to Work, Science Here and so We Want to Make Sure That We Use Science and Studies to Explain Everything in a Very Delay Term Hopefully We Can Do It Because the Other Cannabinoid System Is a Tough System to Explain He Said Were There Hopefully and That's Something That We Want to Do Today with Today's Guest Is Going to Join Us in the Next Half Hour Will Bring All Hope to Everyone This Is Our Next Guest Is Mark Simone and He Is the Only Documented Five Year Survival Are Survivor from D Differentiated Chondrocyte: Please Get an Incredible Story to Stick around He Is Taking His Journey and Turning It into His Way to Reach Others and Deliver Now You Can Fly Anywhere in the World and Paid Discount Prices on Your Airline Ticket Book a Flight to Date Alignment Harassment to Read or Anywhere Else You Want to Go and Pay A Lot Less All the International Travel Apartments Right Now Low-Cost Airlines 800 452 1075 800-452-1075 That's a Got an Old Car Donated Whether It's Running or Not to the United Breast Cancer Foundation and Save a Life They'll Even Come and Pick It up for Free The United Breast Cancer Foundation Has Saved Hundreds of Women's Lives through Their Free or Low-Cost Breast Screening Exams but Now They Need Your Help The United Breast Cancer Foundation Wants to Save More Lives through Early Detection by Offering Women Free or Low-Cost Breast Screening Exams In Donating Your Old Car SUV or Truck Whether It's Running or Not Helps Pay for Them Plus You Get a Charitable Tax Deduction Help the United Breast Cancer Foundation Save Lives by Donating Your Old Car SUV or Truck Call Now for Free Pickup 800-245-0823 800-245-0823 800-245-0823 All Right Now That Number Again Is 800-245-0823 Never Forgotten Apparel Is More Than Just a Premium Women's and Men's Clothing Line It's a Movement to Remind Us to Where American-Made and Serve Those Who Serve Us Our Heroes Never Forgotten Apparel Gives 20% of Their Total Sales to Nonprofits That Support Homeless Veterans and Off-Duty Firefighters and 50% to Individual Veterans and Firefighters in Need Nationwide Checkout Never Forgotten Apparel.com Use Promo Code Matt and ATT And Get 15% off Your Purchase Alright We Are Back for the Second Half Hour Episode for Gut Check Project I Married Grigor Joined Here by Your Host Kenneth Brown and Now We Have a Fantastic Guest Joining Us Today His Name Is Mark Silliman and As I As I Mentioned at the Bottom of the Last Half Hour. He Is the Only Five Year Survivor Of D Differentiated Chondrocyte, The Only Five-Year Survival on Record Eyes Got an Incredible Story of Actually Known Mark for Almost 20 Years I You're an Entrepreneur Your Husband and Father of Three Former D1 Football Plate Would You Where Did Apply Zero Other School like Other Than the University Of Texas I Didn't Do Nothing about Him You Had a Bright Did Not Know the University Nebraska Has One That Texas Tech Has Programmatic When You Get That UniFirst Nebraska That's Royal Memorial North Because of the Cornhuskers Mark Has an Incredible Story and To Briefly Mention I've Known Him for Almost 20 Years Actually My Wife and I Bought Our First Home From You Back When You're Dabbling in Our Building Homes and Even Had Cereal Lunch Manure for a Long Time Go Ahead and Looking at Bring a Jump Forward a Little Bit But Once You Take from Their Which Part the Serial Entrepreneur Report What Are the Cancer Part Well in 2010 I Guess I Would Diagnosed with Bone Cancer Okay and Originally It Was Just Gonna Be a Simple 19 Hour Procedure 15 Hours by the Surgeon Four Hours by the Plastic Surgeon There Were to Take out Half My Pelvis so Actually Had a Hemi Pill Back to Me with Allograft I Was Stuck You Real Quick Good Is Working to Get It That's When You Want Is Not What You're Going to Want Something Different Well Now It's It's It's How It Kinda Hit from You Little Bit So I Remember Bringing My Oldest Gauge over to Your House and This Would've Been an Earlier 2010 Right and You Were Laying on the Floor of Your Living Room And You Kept Saying Rear My Back Honest I Don't Know What the Hell's Going on This Only Place I Get Comfortable Take a Nap and You Are Laying on the Floor of Your Living Room with Her Legs Propped up and Physician Interposition Had Scanned Her Back I Was Trying to Find out Where the Pain Was Coming from and Got Different Diagnoses of a Stretches and Other Things like That They Weren't Working And Then It Led to Someone Look Old and a Little Bit Different Location So I Guess in January of That Year and Coach My Daughter's Basketball Team And They Were Doing a Drill in Particular like the Way the Drill so I Hopped in June This Year and under the Real And Course There 10 or 11-year-old Girls Must like Herding Cats Betting on so I Get up the Next Morning Get This Back Pain Thinking Whelming on Little Older and Will Shape Just Pulled Something Couple Weeks Later Be Fine That Didn't Work So Would It Gotten so Painful and I Was so Restless That My Wife Kicked Me Out Of Bed Not Move the Couch Could Getting Comfort There Then I Moved to the Floor and That's What You Remember Him Sleeping on the Floor No Jumpers Are You Comfort Well up into Two or Three Different Doctors Had Had the MRIs of My Lower Back and Had SI Injections I Went to a Chiropractor for Couple Three Weeks of He Said I'd Be I Can Get You Straightened out New Massage Therapist Went to Massage Therapist Every Day for a Week and She Said I Can Get That That Muscles in This like a Rope and I Can Get How Old Were You When You're Going through the 4445 And the The Massage Therapist Is Heather's New Work Sports Medicine Guy across the Street Want to Go See Him I Walked in And He Looked at Me and Says Will You Come to Get Your Gates, Funny And He Took Extreme up My Pelvis Which Nobody Every Identified My Pelvis Because the Pain Was in My Lower Back And Send Me Cross to the Hospital to Do a MRI of One of My Lower Pelvis Now And I Come Back to Him and in the and in Small Town You, Know Everybody Lives There Will the Radiology Tech Pulls Me Out Of the of the Tube in His Shoes, White until Something Wrong And His Name's Mark Also And Marquis Prompts I Can't Tell You You Just Can't Go Back across the Street See the Doctor Have All the Film Thing Else Will He Pulls up the Films and I've Got This and What Just Lit up on Screen This Tumor in the Pillows That Was the First Indication of Where It Was Always Just a Muscular Muscular Problem and Not a Bone Problem or Cancer Problem Bryant Family History of Bone Cancer or Anything like That Don't Cost My Mom to To Diet Coke Today To Brain Cancer. And She Fought That for 10 Years and Multiple Servers But No Bone Cancer They Can Is It Even Common for an Older Person to Have a Bone Cancer Both Extinct It's Very Rare The Type of Cancer You're Talking about the One That You Ended up Being Diagnosed with What's Unusual about It That Involves Both Bone and Cartilage Nice Leather Coat the Deed Differentiated Type of Cancer Router Actually Goes into Both of Them There Is a KJ's Disease When You're over the Age of 60 That Can Turn into Bone Cancer but Most of the Time It's Kids That Actually Came to Bone Cancer That's Called Osteosarcoma so This Is A Completely Different One It's Very Unique Very Very Rare Well the Congress or Coma Is As Rare and That Was the Original Diagnosis from the First Biopsy Which Is like You Said Boeing and Cartledge and F They Took the Tumor out and Did a Full Biopsy Then They Decided What We Pulled out a Bunch of Homogeneous Sales at That Point in Time and so Controversial, Is Not Exactly What It Is No Matter/in This This Loaf of Bread to Define the The Real Answer and It Should Be Differentiated Which Means That They Can't Tell You Where It Came from Whether Described It to Me Was If What What's the What's the Cell in Your Body That the T Cells That Produced the The so the Osteoblast No Over-The-Counter Blessed Usually It's It's a Blast That's the Precursor No so If I Have a Cell in the Body of Stem Cell or Something That's Going to Create a Fingernail As of the Stem Cell Yeah Okay so the Stem Cell It Is Releases Sale to Become a Fingernail or Hair Follicle And That It Was It's Differentiated So It Goes from What That Stem Cell Is to the Fingernail Will It Fall Short That's the D Differentiated Part so They Don't Know Where It Came from It Ends up And All Your Organs at Some Point Time They There Wasn't There Is No Cure That They Have Found This Point They Just Keep Having Surgeries and Taken Stuff out So What You Think You Know Your 44 Years Old Got Young Kids What's Really Going through Your Brain I Mean Let's Walk Us through Somebody That Actually Unfortunately You're Still Here to Talk about It What's Going through Your Brain That You Had a Doctor Come in Well So Entry Part of the Story I'm in Amman for a Week Four Weeks Actually in a Body Cast, but I'm Laying in His Bed and Can't Move And Now Let the Bones Everything He'll And the First Time the Doctor Comes in Orthopedic Lady She Brings a Guy with Her Big 6 Foot Seven Guy Hi Mark I Want You to Meet This Guy from the Blood Bank Okay Great a Home or Not She's Always She's Just Been No She's Trained in All These Fellows She's Just This Incredible Physician Innovative Because Five Years Prior to The Surgery That She Did for Me They Just Took the Leg off Understand. So You Run Rampant Leg She Had Created and Innovated This This Particular Procedure So the Guy Comes in from the Blood Bank And He Says I Think We've Infected with HIV In One Yeah Blood Transfusion I Think We've Given Your Chubby So I'm Kind of Freak in a Little Bit of Artie Get This This Rehab This Will Be a 24 Month Rehab and Learn How to Walk and Develop a List of Internet Your Company Thanks and Thorne Legibly And the He Was Kidding Right Was a Silly Bit Series And so We Can Freaked out so It Goes Janice and I Gonna Freak out All Just This Conversation but You That I Know It's Only Kind of Well He Comes Back in 0234 Days Later and Says Ride so We've Retested Your Blood It's Not Showing up There's No Markers in Your Blood Will Continue to Test You Will Think You're Okay I Think We Have Something False Reading Which Is Probably Not Coming He's Probably Just the Messenger They Probably Have the Biggest Guy There's like Every Head Every Time We Infect Some Truth HIV-AIDS Has Represented How Often Does This Happen in That Particular Blood Bank Is like Sorry I Got a Get to Know the Room Overhearing. We Have an Assignment You So He Leaves after I Come in the Clear but This Kind of a Roller Coaster of Stuff That You Know You Had the Surgery 24 Months Now You Have a Chevy or Whatever You Get Is No Fight This Fight She Comes in a Couple Week Later Zone Brings Another Doctor and Says Hey Mark You Need to Get Your Affairs in Order Oh Because You Got about That Best Six Months to Live Unlike What Was Going on and so You Ask about What Was Going to Your Head Are You There's Denial First You Told Me HLB's Are Not Buying Your Story Anymore Now You Tell Me That I Got Six Months to Live on the Bind That Story Anymore Either And the You Know He Leaves and Then We Go through All the Scenarios over the Statistics What's Is This Legit How Do You Know Is Is a Misdiagnosis We Believe in Miracles Mistakes And He Wouldn't Talk about Any of That Stuff Just Works on a Positive Attitude No You Have Good Family Good Support Group and We Need to Pray to Whoever You Pray to And the In Order to Go As Best We Can Only Point I Would Become Polytheistic Sure Start Praying to All of Them Well and He Leaves Right and so There Is a Guy in Town Aaron Milstein Was in Town Visited Me in the Hospital and This Guy Delivers Loses Me an Error My Dad I'm 10 Crap And My Wife's Back Home And She Had Heard This in a Cigarette I'm Not Saying a Word Aaron When You Go Home You Not Saying a Word to Your Wife I Want This out to My Wife Comes Back in This Weekend and Dr. Robbie by the Way You're Gonna Deliver the News I'm Not Going to Write so He Leaves And so You Go through the Know Is Calico 5° of Separation You Denial Whatever What You Gonna Do Now Get Your Fair Share Is My Tell You That You Get Zero Liberty Anything but Your Kids And in the Lives of Things That Night I'm Laying in Bed and Talk about Having No Begin Being the Religious Was out Born and Raised in the Church and Hence Have a Pretty Good Religious Background but I'm Pitched at That Point I'm Having a Fight with God More Argument The Stages Brother and This Isn't Happening to Me And I've Got a Wife I Get Three Kids If I'm Good – I'm Okay Back but I'm Not Okay Leaving Them Alone Without Needed to Take Care Of My New Summer Influence Rest Their Life And the Time Marcus Was Third Grade and Then EAN Where like to Fit in Sync with Their Six Grade Yeah They're Not Rulon I'm And Some past Minimum Wrestling in Bed before Because I Can't Get Any Risk As I'm in so Much Pain Amount to Different Campaign I'm Fighting in Bed And, and I Asked the Doctor Early about Miracles Mistakes And I'm I'm Telling You since I'm Sitting Here Pam There's a Just Peace Washes over Me and I Was like I Got This Boot You Have To Worry about It Again from That Point on Never Thought about It Again No New That I Just Knew I Was Gonna Survive My Job Was Just to Sit Back and Let the Doctors Do What They Do Just Survive And I Never Had Another Doubt It Was Just Another Doubt When You Go to All Kinds of Different Emotions but at That Point I Can Pinpoint That Particular Night In That Particular Time Lay in My Bed That Just This Piece Just Should Just Watch the So It Was a Journey so Obviously Held That the Doctors There Was Intervention There Was Medicine Use What Was the First Step and Then Going through That Kind of Schedule Well after He Told Me Also Dine Six Months He Says Renders and Chemo Which One Part of the Original Plan And He Says If the Cancer and Get Your First Chemo Might Take You to His Close like in the Death And so Started at about 240 Pounds And Ended up at Hundred and 87 Pounds Not Hear My Head Not Eyebrow Not on Those Here Nothing to My Butt Crack Nothing Great I Got a Great Plus Track Story I'll Tell You What I Think Is Interesting It's like I Can't See Any Hair Appear Honey Get over Here and Check It Check It You Opened It up so I Got a the Story Them so Now They Get You up to Rehab Right and You Get Move in and and Running It through One of My Jobs Was to Get up Just Walked to the Nurses Station and Back And I Got This Walk and I Get This Go We Haven't Got a Nobel Drama so Don't Fall down And His Name's Alex Left That Matters but Some Walking a Little Bit And I Get a Nurse Station Come Back Think of Had a Good Day Chemo Start to Sit in This Is Going on for Several Weeks Now Now I'm Bald In Almost All My Eyebrows Nothing Else, but Record Showed That Just Run the Story Anyway so I'm Plugging along with This Little Walker and I'm Sweat Its Work And so His Squeak Squeak Squeak Is a Bad Food You Gotta Stop The Guy Gets New Tennis Shoes or Something to Those at the Time No Hearings All Messed up And so That Was Just Really Driving Me Crazy so That You Stop It's Not May Misuse Arts Week and That Is Not Me so Just Stop He Stopped and I Don't Squeak We And Alex That You Know It's Not Me Markets Coming Out Of the Words Come from Is Not Me Maybe It's the Walker That Is Not the Walker Alex to Stop so He Lets Go And We Schooley and a Wooden Walker so at This Point I Am Not Weight-Bearing on That, My Right Leg at That Point What It Happened I Had Worked up Just Enough of Us Went up That In My Butt Crack Every Time I Walked He Would Just Go So Now I Go through All This Every Stop Looking around and so Now I Know That Every Time That I Was Going to Rehab I Was in a Walking Pillow Squeaked That's When I Knew That I Had Accomplished My Goal Don't Use Workup Enough to Wash with Sweat Now Get the Squeak Going and It Was Just the Funniest Thing That I Got a Bazillion Just Hilarious Stories Out Of All This Have a Real Serious Situation but There's a There's A Lot Of Humor in It and You Have Some Humor Chair Otherwise You Know the Doctor Really Said If You Don't Have Some A Positive Attitude about Stuff and Support Your Family and I Completely Believe That Because There's so Many Things in Our Brain We Don't Know That the Brain Does Leases or Controls in You Being You Guys Mean the Doctors Will Have All That Knowledge Young at All, Intellectual Me What I'm Trying to Wrap My Brain around Is When Your Brain Said No We Got This What Did Something I Mean There's Epigenetic's Going on When No I Got This Does That Change Something in Your Body That Allows You To Have a Better Chance of Surviving a Cancer That Kills a Mindset Has To Matter Hat on It Months It's Been a Big Think about Using Somebody in the Office in the Head They Walk around Get That Permanent Frown on Her Face No They're Just Negative All the Time and They Got Those of People Walk around or Just Bouncing off the Water Happy and You Can't Tell Why Is That Is That Genetics Is That Something in Your Life Is It Just Your Attitude What Is It Your Your Physical Appearance Turns into What You're Your Attitude Becomes and If a Negative Note That the Frown on My Face Than You Can See the Body Language That Best Personality That You Become so the Survival Piece I Think Is Is A Lot Of It Is Mental and It's a Battle and If You Decide At Some Point I'm Going with This Then You Can Whip It I Can Tell You That Story but I Could Also Mean There Will Be Another Thousand Stories out There the People Didn't Survive How Do You Know I Remember after It Has a Good While after You Finished Everything You Came up with a Slogan I Think You Started to Incorporate Will Get to It Later but It Was Your Getting What You're Getting Because You've Been Giving What You Been Giving Right And That Can Go Back to Your Attitude Really in Anything Right It's That's Funny I Stole This from Zig Ziglar I Wish I Could Say I Invented or Kept It but It Wallace I Was Gonna Let You Float within the 21 When Her Water, Carried My Wife Work Foreman and Brought Home All the Tapes and so on Wasn't to Home and I Thought Just That's Just so Appropriate Because If You Give a Bad Attitude You Can Get a Bad Attitude and Return And I've Just Goofed around in Different Settings Where People Can Get into a Situation Were A Lot Of Negative Gossip Producing All the Nonsense on Social Media and in the Talking Heads in the News and the Media Nowadays You Going to Setting and Thereby Can Be Fixated on a Particular Item Have This Negative Attitude and You Just Bring One Person in There and You Start Lacing in the Loop with a Positive Attitude and You Watch the Whole Dynamics of the Room Change yet and It's Kinda Interesting Just Somebody's in the Coming Change in Attitude and Works the Same Way yet I Just Know Where to Listen or Ask Might so That's a Big Long Name for the Cancer but It's a Type of Bone Cancer but Is It That Is There Any Other Way to Describe It He's Asking If There Is Any Other Way to Scratch I Have yet Forgot What I Thought As I Have Found Art but That Is Any Other Way to Describe That Type of Bone Cancer Mark The Lie We Had a Listener Who Is Written in and Wanted to Know Better That Long Night – GD Differentiated Congress or, Yeah Indeed Differentiated You Can Convert Sarcoma Condo Sarcomas the Common Name for It but Because It's Special The Differentiated Gallic Alec up and I'll Just Text a Link Back to Them through Spiny and yet It's a It's It's Rare It Say There's Really No Other Way to Describe It Other Than You've Got This Cancer That's Crossing over between the Cartilage in the Bone and This Is Forming The Cancer That's Coming to the End of the Pelvis like That The Edges Sounds While I Equate Just Give Us a Rundown and Then of What the Activities What You Had to Do I Know They Had to Do Chemo You Had Your Surgery So Yeah so We Had 19 Our Own Record of Good Story in This So You Know Is Doctors Going for Any Kind of Surgery They Give You the Purple Pen Right Operate on the Right Knee and so As the Patient Number Right Now No Make a Mark on My Knee Right Knee So When You Go and You Don't Screw up and Mark the Light on the Left So the Plastic Surgeon Guy Comes in and He Still Me All That Were Gonna Do And They Were Going to Take 6 Cm Out Of the Middle of My Stomach All the Way down Past My Bellybutton up Got a Whole Brand-New Bellybutton by the Way And There Were No since This Backup Okay and Their Rent Their Creighton Flaps If You Think about Taking a Big Jump Folgers Coffee Cup Put Record Your Pelvis and Pushing It Always through Your Body Everything That Went into That Coffee Cup Ended up in the Trashcan Okay so You Got a Cavity There Now What Are You Going to Do so They Were Taken the 6 Cm Out Of My Lab to Put into This Flap down Here to Keep My Insides from Falling up the Backside These Pointers Right Going Right Drawing and the So I Took That Purple Pen and I Said Dr. Reese Make Sure You Leave Me a Sixpack Abs on My Stomach I've Never Had a Sixpack Abs I Thought That Was the Only Chance I Was Ever to Get It and He Did a Pretty Dang Good Job But The Orthopedic Lady Worked for 15 Hours Straight And in the Plastics Guided a Four Hour Surgery on Same Day on the Same Setting And so 19 Hours Totals, It's Amazing Crazy That Is a Long Surgery Which Is I Mean Just Absolutely Incredible Because A Lot Of Times We Talked about Where Medicine Fails but Certainly You and I Talked about That True I Feel like Medicine Could Be Doing a Better Job For Instance Controlling Diet Right Then We Have That 15 Hours Surgery That Is Incredible This Is Where It's Definitely Succeeding Yes Well You Guys There's a Reason Why They Call It You Practice Medicine Because There Is Little Perfection in It Because You're Operating on Human Body Which Is Imperfect to Begin with Right And so And We Talked a Bit Earlier How Went from from One Dr. Trying to Chase down a Diagnosis and I Feel Fairly Fortunate That Each Doctor Said I've Tried I've Made an Attempt and I'm in Have To Send You to Somebody Else and so I Kept It Referred over and over and over It Might've Been a Frustrating Situation but in Reality the Doctors Practicing What He Knows And's Finally Stops and Says I Think There's Somebody Better To Help with Your Diagnosis or Help Push You down the Track Where You Need to Be so Appreciated That That They Weren't so Egotistical That Said I Got This in the Switch Problem Is in and Sit Me down You the Wrong Path so It Was Kind of a Neat Progression That See How the Physician Community Just They Work Together Come up with Right Diagnosis at the End of the Day So Then What Were the Were There Any Other Foreign Bodies Any Other Animal Parts That Maybe You're Sporting Right Now That Didn't Just Belong to You Well So I Have Somebody Else's Pelvis and Me Okay and I Don't Know Are You Going on Animal Parts but While I'm Here Here about a Man Not Really Sure so the Good the Joke Is That They Were Looking for Similar Pelvis Same Shape Same Size the Telegraph You Know of Cadaver Bone to Bone And the Want to Find Something And They Finally Find It in the Comments Aren't We Can Do Surgery on This Particular Day Now You Don't Have a Whole Lot of Female Orthopedist Right And the Lady That's down at MD Anderson Is a Female And so I Thought That Was a Little Unusual And I in My Day Job I Do with Physicians All over the Country And so That's a Little in Common So I Go to the MD Anderson Website Liquor up And It's Black Lady Which Makes It Even More Uncommon And When You Meet Her You Go Oh My Gosh You Are Perfect for This Job You Are the Right Person She Is a Freak and Ball Buster and She Always Had All These Other Physicians Following Her around Because She Was Kind of a Pioneer in This Particular Type of Procedure so She Had Called And Finally Found the Bone Mrs. Art Room Schedule Surgery for This Particular Day How Does She Do That like Can't Even Begin Looking for a Pelvis It's Going to Fit In a Could Ever There's a Bone Bank And Oh so You – and Then Donate Your Organs and the and This Is up California and This Is Another Funny Story That I'm at a Conference That I Go to Once You're Always with You Guys In All These Vendors Are in the Know in the Exhibit Hall And I'm Talking about My Story It to This One Guy Nieces Where Did You Get Treatment Sit down in Houston in the Engine Just When Did You Do That Is It in July 2010 I Think I Know about You Simply Mean Sidwell My Wife Works at the at the the Bone Donor Place Whatever It Is Where They Freeze All the Stuff and She Was Working Going to Bone after Bone after Bone to Try to Find a Picture When It Was This Size and Had to Go to Houston and Bob Baugh And*The Chief I Was Least Found She Was Looking for Shoes As It Will This You Know Anything about the Person That I Got It from And She Says Yeah 300 Pound Black Lady So I Thought I Got This Black Doctor Working on Me I Got This Black Bone in Me and I'm Have a Soul When I Come out Here You Do Dance Better No I Do Not Either to Help Me up Here But I Forget What Your Original Question Was about Diverted into the Wrong Snow We Were Just Talking My Animal Yeah We Just Just the Different Different Graphs That You You Had to Use Mean Here's Surgery Although It We Already Know That It's Long There's There's a Process to It Is a Process to the Chemo There Was a You Had the Best Attitude but It Was Still Work but I Can Still Remember That the Months and Months of of Watching You Show up Tell Your Kids Athletic Events and Games Try to Pull the Truck As Close As You Could to the Football Field You Said You Could Watch and Participate In Family Activity and Every Time I Stop by to See You He Did All You Could to Smile and I Knew That It Was Difficult But You Made It through… Told and Believe Miracles Mistakes Not I Think I'm a Walking Living Breathing Miracle You Don't Ever Take a Single Day for Granite Because If You Have yet Sit and Think about It for Second Get Your Affairs in Order Get Six Months to Live I Think That Would Change Your Life a Little Bit The Things That You Would Miss Definitely so It Just Enhances Your Attitude There Is a Great Day Rated below When You Got to the End Of Basically Felt Okay We Are in the Clear Now We Are Now Are Counting Months an Hour to Count Years of Mark's Survival Time What Was the Turnaround Said Okay We've We Got to the End of What Were Going to Do with You What Was That Day like and Then How Did You and Susan Then Susan's Wife Is His Wife's Name by the Way Has You and Susan Then Began to Get into the Frame Set of Okay We Are Now Moving on with Our Life Everyday's a Great Day And Then Sending Our Accounting up and Yelled Me to a Year Then Is Alluded to Earlier You Made It to Five Years an Hour Already Little over Seven Right So What Was It like No One Halyards This July Night 19th 98 so I Was off the Year What Was It like to to Get to the End of Whatever Therapy That What's so I Mentioned before I Start out 240 Pounds How Is It Jim at Hundred 87 Pounds Indicator Where We Live They Have This I Didn't Have Any Idea but Had at the Time There's a Service That Would Flock Cancer Patients to and from Houston for Free Guy Would Take Any Money If You Driven to Houston It's Not the Most Scenic Drive from Dallas-Fort Worth to Houston Is, Beating Long to Yeah So He Put You in a Plain Little Private Plane to Fly and Drop You off a Millionaire Take Unicorn Delivery to the Hospital and Then Come and Pick You up When You're Done Instead of Being a Five or 6 Hour Dr. and then up in an hour and 1/2 flight which was Fantastic So to Start the Process I Was in Pretty Good Shape Other Than a King Physically Move Mentally I'm Okay But by the End of the Process Nine Months Later Shriveled Withered Enough That I Can't Physically Get Out Of Their Plane And Susan Had to Call Somebody in Town to Come Pick Me up Physically Pick Me up Put Me in My Car Because I Couldn't Do It Myself And I Member Were Driving Home And Just Exhausted And Grind and Say I Can't Do This Anymore Unfinished and He Said Either the Cancer to Get Your Chemo Going Get You At That Point I Was Done of the Chemo so We Call Them Safe Were Done And so Think with That Tortured You Enough That's Reasonable We Have Got to Finish That Story in the Next Half Hour and Then We'll Talk a Little Bit about That Same Charity That Flies People down to Houston Because Mark Decided His Journey to Lead and Inspire Him to Do Something That Is Really Cool Thank You for Sharing That We Had Movies Get to The This Is the Only 24 Hour Take Anywhere Platforms Dedicated to Food and Fun We're Spoony Our Townhall.com, the Special Counsel's Rush Investigations Walking Fresh Speculation the President from May Pardon Some of Those Charged in the Probe Some of the President's Closest Advisers and GOP Allies Fear the Pardons Could Set off a Political Firestorm The President Preparing to Hit the Road Later Today As White House Correspondent Greg Clugston Explained for the First Time since Being Cleared of Russia Collusion by the Special Counsel the President Goes before Thousands of Supporters at a Michigan Rally This Evening Political Observers Will Be Watching to See How Mr. Trump Addresses the Issue Which Could Be a Preview of How He Uses It Politically during His Reelection Campaign the President Calling for the Resignation of Democrat Congressman Adam Shifts Chair of the House Intelligence Committee on Twitter the President Writes a Shift Spent Two Years Knowingly and Unlawfully Lying and Leaking Mr. Trump Also Talking about the Just a Small Laissez-Faire Writing That the FBI and DOJ to Review the Outrageous SEs Smell like Case the Presidents Blasting Chicago Prosecutors to Drop Charges against Millett Tweets Their Handling of a Quote Outrageous Case Was an Embarrassment He's Calling on the FBI and Justice Department to Investigate Correspondence Argument Johnny Says Mr. Trump Altercation Embarrassment to Our Nation Facebook Being Accused of Housing Discrimination Charge Leveled by the Department of Housing and Urban Development HUD Is Accusing Facebook's Ad Platform of Encouraging Enabling and Causing Housing Discrimination Facebook Recently Vowed to Overhaul Its Ad Targeting Systems to Prevent Discrimination in Housing Credit And Employment Ads a Seattle Bus Driver Being Lauded As a Hero despite Being Shot and Wounded by a Car Jacquard He Still Managed to Drive His Boss with a Dozen Passengers on Board Out Of Harm's Way While Street the Dow up 48 Points More of the Stories at Town Hall.com Take the Pain Out Of Ordering Your Diabetic Testing Supplies with Diet Thrive Diatribe Ships the Testing Supplies You Need Directly to You When You Need Them Best of All with Plans Starting As Low As Eight Dollars a Month Diatribe Is Probably Going to Cost You Less Than What You're Paying Today Diatribe Is so Convinced That You Love Their Service They're Offering Your First Month of Supplies Three Simply Type the Kodak DOC and Checkout Diet Thrive.com That's DIA Thrive.com Have You Done It Did You Catch a Glimpse of Yourself in the Mirror I'm I'm One of Those People You Don't Want to See Naked IBM Most of Us but I Mean You Look and You're Going to Die I Don't Get Whatever All It's Horrible Hey That's Doc Townsend and Brad Staggs to Tell You about a Different Way to Shed Those Pounds This Is Brand-New Technically Been around for a Couple Years or so It Was Based on Research from the University Of California That Said There Is a Molecule Called OEA That's Found Naturally in Your Body Produces It in the Mediterranean Diet That When Taken Concentrated Amounts It Will Actually Make You Feel Fuller and Boost Your Metabolism I Lost about 10 Pounds so Far Is an Amazing Ballet School Company Said We Can Take This to Market to Make This Great Product Will Help You It's Called Reviews on Our IDU Zone.com Our IDU Zone.com Brad's Work Does Were Comrades Work for Me Countless Other People Go to Read You Zone.com and Try Today You're Gonna Love It Read You Zone.com Remember That Our IDU Zone.com Are You Tired of High Cable TV Rates Sign up for Dish Today and Get a $500 Bonus Offer While Supplies Last Loss Locking Your Price for Two Years Guaranteed Call American – Your Dish Authorized Retailer Now 800-570-6630 800-570-6630 – 800-570-6630 Authors Required Critical Negation 20 from Early Termination Fee Any Auto Restrictions Apply Call for And Welcome Back This Is Going to Be the Second Hour Episode Forever Getting Project Here with Your Host Ken Brown I Am Eric Rager Joined Today by Mr. Mark Silliman Will Continue His Story Here in Just a Brief Moment Quick Reminder If You Want to Get Your Daily Polyphenol Fix Pickups and Are Trying to Let Love My Tummy.com/Spoony He's Wearing It All Right Here in so Many I Love That He Just He Just Took off Her Sweatshirt and There It Was Perfect We Are to Get Comments Today so You Go to Get Check Project.com and You'll Take Straight the Page Go to Connect You Can Send Us Messages What Is Really Cool One of the Listeners Said That He Deftly Checked His Ego at the Door so We Call This the Jet Check Project You Really Can't Learn If You Think You Already Know Things so The Ego Is the Biggest Enemy to Learning So We Ask Everybody to Check Their Ego at the Door so We Can Talk about Anything Including Squeaky Butts Squeaky Bats Mark Did That Right off the Bat First Half-Hour Ego No Enzyme No Ego and That One at All No No No Hate Mark so We Are Rounded out the Last Half-Hour You Telling Us That You Had Been at the Point Where You're like I'm Ready to Stop Not Being Able to Get Out Of an Airplane And You Finish It up on That Story Where You Began to Emerge Out Of Therapy and and Post Cancer Treatment Will The Treatment Part Was over Now Just to to Survive So I Go Back Every For a Long Time As Every Month First Year Goes by Course Masking the Chemo Doctor Now Tell Me Statistics Many Survivors Do We Have No Who Else Is like News out There I Get Nothing They Could Be Grim Nothing You Know When I Don't Talk about That Which Have a Good Attitude We Could Move Forward Right So It's Every Month Asking the Same Question Back down Houston Finally Had Your Two Rollaround Same Questions Same Story Give Me the Same Answers Showers and a Great Attitude about Improbable Your Three Rolls around And or the Statistics And He Finally Coughs up That We Gotta Have People You Can Have a Data Backup Patient Right Now We Got a Bunch of Patient Statistically like You Tell Me Where a Man How Many of My Mother Would Get 455 Patients in Our Database And I'm Thinking I Am Not Sure That's a Statistical Analysis Enough of the Sample Size for Statistical Analysis May Be so Mean Spirit Better Than Nothing Sure but That's Only Give Me at That Point so Your Four Rolls around And I'm Beat Them up Again Whether Stats Only People like Me except Her And Get Better and Put on Weight Grumble Her Back The One Closer to Normal Aside from I Don't Have a Groin Muscle and Half of the Hamstring Muscle In Somebody Else's Pelvis and We Can so It… I've Got Some Limitations in the Things That I Physically That I Can Do And Give Many Statistics Year for He Finally Says Will You Are the Only Patient That We Have Had That Hasn't Had a Reoccurrence In the It within Four Years so to Bed Mentioned Earlier That That Then Take out the Tumor but They Don't Know Word or the Genesis of the Cancer So It It Affects All the Rest of Your Organs and He Had Said That And We Just Take out Organs As They Go on to You Can't There's More and We Can't Take out and That's It You Your Done Lights out So He Says You're the Only Case That We Have That Has Had a Reoccurrence of the for Your Mark Five Years Rolled around I Give Him the Same Questions And He's Pretty Excited That Point And He Says You Know I Think I Found the Secret Elixir to Solve This Problem He Lost His Brother to This Type of Cancer so He's, Dedicated His Life to Solving the Problem Whoa And He Says That I Think I Want to Go from 0% Success Rate To 20% So Go Seem the Following Year and How's All That Going Were the Stats Not until Manning and He Says He Is Buried I Don't Use Were Depressed but He's Not It's Jovial and As Happy As He Has Been Because He It's What He's Doing Now What He Did on Me Is Not Working on Other Patients so He Where He Thought He Had Found Some Kind of Cure to Help Some People It Had Worked so at That Point He Said We Still Have Any Documented Survivor And I'm Now at Nine Years of Be Nine Years of Some And so for Lack of And One Was Living There Anybody with This Type of Cancer They Get Funneled to MD Anderson to Take Well It's Rare Enough That I Don't Know That Everybody You Know Can Identify the Particular Type of Cancer and They End up at Anderson Sure You Know That I Feel Fortunate Enough That I Had Doctors That Said Well You Got Something's Kinda Weird Here and I Think You Need to Go on Those Centers of Excellence So My Mom Spent Middle Years Go on the MD Anderson and I Had Experience That in the Care That They Gave You There's so That's First Place I'm Going But There's Other Places in the Country That These Guys These Researchers Shared Information Back and Forth I'm Not Saying That the Dr. Robbie Had 455 Patients of His Own Don't Hate They've Collected This from from Other Clinics or Other Centers of Excellence and Greatest Database and Sharon Research So You Were Patient Number One To Make It to the Five Year Survival Mark and I Did Not See Him in January and Still Go Back Every Year But I Didn't Get Him on the Schedule So the Orthopedic Lady but This December Want to Go Back I Will Make Sure I Have Him on Schedule so I Can Give Him One More Time Right Where the Stats We Also like Me Is There Anybody Else out There That's That Surviving How Are You Doing to Your Cretin The New Elixir Saul Somebody Else's Problem It's Crazy but That's Just like When You Are down to Your Last Dollar You Don't Know How You're Going to Get Out Of the Casino And You Going to Put It on the Table and Hopefully Hit Hard Eight or Something like That so That She Could Buy the The Flight Home That Is Exactly What I Was Thinking throughout the Whole Story Yes They Can Blackjack the Whole Time That's All I Mean That's That's All and Its Outlets Actually It's Craps but so March I Whenever You Talked about the Flights down to Houston This Whole Journey Inspired You to Take up a Completely New Hobby You Still Have Your Other Job Where You Still Deal with the Orthopedists and That's Obviously Something That You've Done Well in Your Own Entrepreneurial Spirit Etc. but You Took up a Completely Different Line of Hobbies And Wanted to Tell Us Little Bit about That Well so the Guy That Runs This Nonprofit Indicator Kept Busting My Chops Marketing Learn How to Fly Needle Half-Life And Off-Line Looks like A Lot Of Fun Theoretically at Coming That Looks, Your Fighter Pilot Doing All That Stuff but When You Actually Watch What They Go through and What They Do and What They Have To Know and Learn I'm the Guy That Wants to Put the Key in the Car and Just Go Right I Don't Know All the Details and All That Other Stuff Is Just One Draft Just Want to Go and Watch Him and All the Stuff That He Does Fine so There's No Way So I Mentioned Earlier That He Wouldn't Take Any of My Money So the Only Way That I Could Give to Him Because What He Gave to Me Didn't You Get Good or Given Which Given I Decided to Volunteer They Do a Charity Bicycle Race Every Year in August a Week or so before Hotter Than Hell And We Have People to Come from All We Had Somebody from Czechoslovakia and Australia with People from All the World That Show up This By Chance And Then End up in Modern Hill in Wichita Falls Which Is Kind of a Cool Ride so These People Arrived in Sandman This Is A Lot Harder And Harder Than Help Is How to Enhance Flat You Have Some Hills to But It's Pretty Good You're Right in the Trees and on the Country and It's a Little Bit Different Anyway so I Volunteer My Time for This Bicycle Rally And of Course He's Given Me the Mark Geller How Fine You Gotta Do All the Stuff in the Next Bobbio He's Cuban But As Names Fob You And We Say Five You Think of Long-Haired Guileless on the Harlequin Romance Books and Stuff up to Another Five Euro Story in a Minute but Anyway so Bobby I'm Not No Money to Do It One of the Ladies That Runs This Kind of Head Pet Dog in Charge of the The Bicycle Really She's a Doctor in Town Jesus: Clients Not like That That's Just Bob You What You Comply with Me and I'll Show You What It's Really like Pilots Live in Decatur It's Not That Big of a City Is Only Five 6000 People Live in Decatur but 74,000 Pilots through the You Think Everybody's Flying Planes Yeah She Gets Me in and Select Jeep Punching the GPS and the Plane Just Takes You There Right Skunk in Your Car except You Gotta Drive Give a Gas and Brake When a Plane You Just We Put in the GPS and It Just Goes I'm Oversimplifying Thi

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493: Nutrition and Herbs for Anxiety

Play Episode Listen Later Mar 24, 2019 21:14

In today's episode, Gina shares her knowledge of nutrition and herbs in the context of anxiety. Gina recommends foods and herbs that help alleviate and reduce anxiety while also indicating what foods and herbs to avoid to keep from making anxiety worse. The foods and herbs are discussed not only in the context of anxiety but how they can benefit overall health. If you suffer from bloating or abdominal discomfort, or suspect you might have symptoms similar to IBS, Atrantil can help. Go to http://www.lovemytummy.com/acp and use code acp for 10% off of your own Atrantil today. To learn more go to: http://www.theanxietycoachespodcast.com Join our Group Coaching Full or Mini Membership Program Learn more about our One-on-One Coaching What is anxiety? Quote: Bodies always tell the truth. They give us hints of how to listen for it, and to recognize it when we hear or see it. ―Robin Rose Bennett

health anxiety wisdom food wellness nutrition ibs herbs atrantil robin rose bennett

Chef Patrick Mosher, cooking for many, the science of healthy food on large scale

Play Episode Listen Later Mar 21, 2019 115:58

Chef Patrick joins the show, also serving as producer of GCP for the Spoony Digital Radio station, to discuss the launch of the new show, planning executive chef level meals for large groups, and medical vs restaurant trivia!https://kbmdhealth.comhttps://gutcheckproject.comHey hi Mandy if you don't know me it's probably because I'm not famous but I did start a men's grooming company called Harry's the idea for Harry's came out of a frustrating experience I had buying razor blades most brands were overpriced overdesigned and out of touch and here is our approach is simple here's our secret we make sharp durable blades and sell them at honest prices for as low as two dollars each we care about quality so much that we do some crazy things by world-class German blade factory obsessing over every detail means were confident in offering 100% quality guarantee millions of guys have already made the switch to Harry's so thank you if you're one of them and if you're not we hope you give us a try with the special offer get a Harry starter set with a five blade razor weighted handle shave gel and a travel cover all for just three bucks plus free shipping just go to Harry's.com and enter 5000 at checkout that's Harry's.com code 5000 enjoy and welcome back to the chase project episode number three we are still here and love and we think we can keep doing this to like episode like Joe Rogan episode number 2068 they still let us back on 2068 means only have 2065 the ghetto Jordan close we are getting closer so thank you again for joining us that the feedback is that once awesome it's a it's impressive I had no idea it this many people in such a short amount of time and want to hear what we had to say about bridging the gap between health and nine natural and medical science absolutely I love it we've been as we get to hear shortly is a big message by a bunch of people and had a lot of friends from you know all over the United States contact us and say hey that was that was interesting is recovering some cool stuff special last week with Sean Brian's on if you did not check it out please deep dive into CBD and a little bit into the cannabis industry but really cool such a deep dive that the material was so informative that YouTube of course allowed us to keep spreading the message but Facebook will hold our our recording down for little while we had replaced it with YouTube so I guess if you want to know the truth then sometimes I suppose, slow down a little bit about the debts and we covered those topics like they obviously did that because of the particular topic that were time as we are all about the science of it where showing everything that's working to do really continue to do this and today what could we have our show today we are going to be joined by Chef Patrick Mosher now if you listen to the spoony network already chef Patrick Mosher is already somebody they are quite familiar with however get experience from all different aspects of cooking for gigantic hotels being a part owner of some large chains and putting together the food items ever essentially he's he knows how to build food and how to make something out of his message is you are what you eat my messages all health begins and ends in the gut this is why teaming up with chefs and getting out those can be supercool thrilled to have him is actually the producer of our show so this is going to be any reason to tune in to be that were to move him over here and easier to be a guest so we had to on the fly he had to on-the-fly teach Eric's wife Marie to run the to the production desk over there so if anything let's just stay tuned for that because as a camera isn't where it's supposed to be don't be mad at her doing what she did she just learn how to do it two seconds ago hey you can't blame her for me setting the camera incorrectly can't blame her yelling at the right way that are really fun though regardless speaking of let's get caught up on our on our recent week weekends anything big happened with with you and your families last week it's pretty chill something conical I just mentioned a little bit about how people been messaging us now remember we are the gut check project I phrases check your ego at the door everything is on the table and somebody had messaged me on Instagram and asked why do we what was to get your project Y check your ego at the door and only last week was actually my birthday on our show and I I read a book written by Ryan Holliday called the daily Stoic all this is a fun little way to start your day by those every single day he takes a lesson from a Stoic philosopher McKenna dumbs it down and gets it through okay so March 14 was one that I had I thought it was way too coincidental that somebody message me for this and this was the actual thing so bear with me while I explain this but it makes total sense to me and this is the kind of stuff I start my day with so the quote is from DRG this layer to this Zeno would also say that nothing is more hostile to a firm grasp on knowledge than self-deception so what I like about it Reinhold he then breaks it down basically says self-deception delusions of grandeur these aren't just annoying personality traits ego is more than just offputting and obnoxious instead it is the sworn enemy of our ability to learn and grow as Epictetus said it it is impossible for a person to begin to learn what he thinks he already knows today we will be unable to improve unable to learn unable to earn the respect of others if we think were already perfect and a genius admitting it so that was the philosophy that you and I have ordered set up the show it's got check project check your ego at the door sitdown and let's learn from each other let's teach each other and that's why we have a chef on today is regularly about food right we deftly learn little about food you well it's good question so I speaking to my wife who is going to work in Camas today for a show thank you Marie this this last weekend we spent our time with my boys putting down a new floor on the chicken coop so alive has had experience in the past we've had her own chickens and we harvest on eggs is the best tasting as you can possibly imagine but if you like spending around 72 $73 and egg get yourself some chicken because it's awesome they taste terrific buddy on the great that reminds me because I do believe that you guys tried some beekeeping at one time you and I put together what we've taken care of carob some patients which I'm sure that be okay with me saying that that they were beekeepers so there was a Dr. Robert Bender was a gynecologist in town unfortunately died of cancer but it was the funniest thing having lunch with him and he thought about how him and his wife decide to get into making honey results fantastic to goes I'm a gynecologist I know how to deal with women I sent you will treat one queen really good and I get all this honey and were selling this honey its local natural honey it's $7.60 a bottle only cost me 28 per bottle exactly what you say and I love that guide I love the quote unfortunately always best on book I like it when people take risks like that kind of owner will completely own it, check your ego at the door to tell you that were having fun doing it were not making money the farm fresh eggs taste great we just got to get to the point where we don't have our dogs take chicken that's others to hate the originals you mentioned a book and some is really cool/we even reading this book from Isabella Wentz ideas yes you and I both receive this fantastic book Isabella Wentz is an amazing PhD once you haveso can I fortunately meant to admit Isabel and her husband's a year and 1/2 ago when were working in San Diego and she was diagnosed Hashimoto's and dad she then asked she was diagnosed with Hashimoto she went on to change her diet laminate some of her triggers trigger foods like gluten and dairy containing foods and then began to find that she could eliminate out that inflammation and put herself on a road to recovery it's not any different than what you wrote out what you have the Stoics book the reason was to get to project what dad Dr. RI what does chef Patrick's going to join us and talk about how you can control how you feel with great food it's no different so thank you very much Isabella for Isabella and your husband's name but will find that out and thanks so much for sending us the book W read this to recommend it to my patients you done an amazing job oh yeah Hashimoto's food pharmacology food pharmacology comes with a full meal plan at the very back with all the way down to what exactly what to buy inmates like any other recipe book but it's it's high quality tell you why why you're doing what you're doing not just eat this for here's what will do will all of them will all read come back into her like a sort of synopsis of the book once again as well thank you so much for doing that supersmart woman love talking to her when we were in San Diego with my insurer meeting that was awesome definitely absolutely season quick catch up for listening here on spoony don't forget if you want to drop by and pick up some love my tummy.com/spoony for your own are trying to heal you get a discount for using spinning is the discount code as well as check out KB MD health get your brand-new KB MD CBD in our new store so if any of you have ever read Isabella Wentz's books or if you enjoy the show at all we are all transported to other this is a rising tide will lift all ships one way to do that is to actually go to these websites purchase a product and use those codes so that everyone is trying to help each other out we want to make sure that Chef Patrick has a successful show and his network grows in the spoony radio digital platform becomes massive and one way to do it is definitely going on and supporting our sponsors without question without question will get moving here when our first half-hour and dad, the format is that we touch on health matters as they come through KB MD health was to talk about here the gut check project so can want you tell us a little bit about what is on your mind healthwise today so one of the things I mean I'm a complete nerd so you want to geek out at some point in the show and I was thinking of the articles I but I basically spent my nose in journals all day long and starts trying figure stuff out but then I came across this really cool article about the science of food and it just falls perfectly into this Hashimoto's food pharmacology and were to have Chef Patrick on here so no food is fascinating why do we like it does so many things you've got texture you've got smell you taste the consistency of it there is a whole science cold food pairing Scientology porcine science science and science technology and technology articles food pairing technology Where you look at this and you can actually manipulate which we like for instance one of the examples were the more simple examples would be like when you eat really fatty meal ribeye right will the lubrication that happens on your tongue if you do too much of it you can balance that out with an astringent thing that actually binds to proteins and gets rid of that slimy field okay so it's the balance you don't want too much of anything guess what is very stringent read one that's how come red wine pairs so well with a good adding ribeye has and an actor just get that to go away so I started going down this route a whole family's articles and I'm sure that this is second nature to the chefs out there and the other golf course that is but this work is really fun as it turns out only 20% of your taste is actually happening on your tongue okay 80% is the aroma and it's the aroma the terms on everything else so the we perceive the aromas because they interact with our olfactory nerves so as it turns out these different aromas do different things and you can augment them we talked about the entourage effect last week you can actually have an entourage effect when it comes to food by pairing certain foods that have chemically similar aroma molecules okay so in and before you do for my taking a sip of this be similar you said that you would use an astringent to basically cleanse your mouth it's really probably no different than using I'm guessing Ginger whenever you're about to eat sushi so the ginger works like that exactly so as it turns out like for instance did you know that like white chocolate and caviar go very well together did not it's wild because when you put it through when you take these foods and what the scientists are doing is they're taking the foods and they're putting it into a gas chromatograph okay and what that is is that is something that actually shows the molecular weight you can go out here despite your spike these two foods share similar spikes as it turns out white chocolate and caviar share similar spikes in that molecule is trimethyl Ammon Miriam smells like fish sure does in fact there's a disease on the side note: try methyl or I'm sorry it's try meth alanine is the molecule trimethyl and manure is one that I'm familiar with is I've actually had patients come to me and like it's weird when I eat certain foods people can't be around me there like you have a weird odor that's called trimethyl Avenue area and it's that molecule which is trimethyl M and trimethyl amine certain people have a genetic predisposition with the Caprica and I looked at them going to do anybody receipts in a like for like yeah and Mike got in all we do is change your diet problems gone yet so I could you start looking at some of the stuff in the science behind it is so cool when you're looking at the interactions what can happen is that you can have similar molecules that paying your olfactory nerve to go to your brain and go oh that's this and then if another food pairing pink that same one a little bit a little more little less so on then it heightens the first one so you can build your recipes and food off of the molecular structure and beyond the whole tongue thing you know the sweet salt bitter sour mommy the new one the earthy flavor of this is the way to really take your food to the next level and much of what chefs have probably learned Michelin star rated shaft is there already doing it without realizing that it could be based on the science of this church so for instance like a large portion of a strawberry actually has cheesy molecules really so you can sit there and pair strawberries with a certain cheese and it will augment each other the they will build each other up so really fun I never would've thought about this checking my ego at the door I start going down food science because we got a chef on the show today and then this opened up the whole thing right on the UK website now just real quick it would just be any kind she's surely has to be you would make strawberry nachos I'm just saying I can a case on top of the pile strawberries no no it has to be certain she's with similar molecules okay that have this yet and so you can go to food pairing.com and my kids are having some fun with this today where you can create a recipe so I so I looked out to Chef Patrick give me a protein anything you want give me some food product or to build a recipe offer right now live let's go with duck duck so this done whereas I specifically duck breast reason to start with this not a malady yeah okay would you like to be wild yes okay wild now will begin to do is somebody has put a duck breast into a gas chromatograph and they have figured out how to actually pay the so now foods that are similar or foods that have a molecular component that is similar include all kinds of different stuff but basically here we go I think that you should pair this with as it turns out Remi Martin cognac that's why he had his first thinking online CLE source any serious interest in their honor will find out right here what we put a citrus solicitors one day before he answers Patrick what kind of citrus would you would you already kind of will intuitively think it will because he thinks something is sweet yet astringent like can I do colorize right so you have this rich duck in and it's not just a fat ass again okay accommodation all the flavors some curious if if the classic pairing in particular is one that comes up one would match okay and also so fun about this is that now or build it so I an interesting fruit that you showed up as persimmon oh so will add that one so now it's happenings were build missile recipes so you can decide how you do this so we have the ability now to realize okay why do certain foods taste good so my son Lucas and I were talking others were having fun today looking at this and he goes wait a minute is this a way to prepare foods so that the healthier foods will seem like they taste better take so like I want to put tail and do something else with that and I'm a parent with something that'll augment the cheesy flavor of something else use less of that more of the tail they help each other out like this facet of never ever ever heard of using food pairings through molecular studies to possibly trick your brain into liking the food more making healthy food more appetizing making healthy food more appetizing as well yeah interesting yeah so just come and follow things left my nerdy clip of the of the of the show youngest and hours on there now you just ruined her life anyway though I am so what you can do is you can actually Savior food parents and my kids were doing this also and my daughter Carla built a 40 or 50 when we look at it here she started with C Urchin okay branched out and we've got all kinds of stuff see urgent tied to cow mozzarella which eventually takes us to buckwheat and you can just see how much fun this could be were you could do this and it's it's based off the realm of what I loved about what Lucas said was let's make healthy food tastier sure and do it like this sure a lot of chefs probably know this but this is a way to actually use this as this is the style that I would do when I have the Hashimoto's food pharmacology going on to make it taste a little better as a way to do nano kid let's answer bets and brilliant tool that I had never been exposed to Alec some of the idea that foods could make you smell all the different onions for instance I may not love onions but if not grilled in your eating fresh onions it's MS your partner is also eating onions it sets, no go right you and I had a discussion on and I wanted to rail us off of of building that the foods to make them taste better but wasn't that long ago you and I had a discussion about what asparagus does to urine and you said that somebody was doing a test whenever I believe you are in med school that they were basically trying to figure out how fast somebody could rapidly make the the year and change its odor from consuming disparaging of that conversation is absolutely so back in the day this during my fellowship Dr. Wessler was the was a pioneering guesser elegy he's the guy that figured out that there is such a thing as lactose intolerance and we say that like it's nothing but somebody had to figure out that there's an enzyme called lactase and so he was as it as a scientist and document it was kind of fun because he would give us a lecture every year and the fantastic guy is in his 70s just kinda having fun with us each a part-time no part-time lecturer and it would be the same lectures would be lovely pictures from like the 70s it's awesome he made everybody eat a bowl of asparagus and then they had to go P and never really had the time when they could spell when they could smell the asparagus is because that was his absorption study which are not only do away with that now ribs like you ever eat this brilliant. We started smelling yeah yeah the take away whenever you were doing that they were stressing how quickly it happened to break down the food I was really quickly in these molecules that do this – get in your bloodstream and get filtered through your and some of them remarkably quick so what do we handle distribute on about onions when people take Allison which is a garlic extract that they will actually use the garlic out of their breath out of everything because it just gets absorbed so much and that's one of the issues that my patients will have in the company will be taking supplements be like something's wrong Mark are you and Allison like yeah Mike I could smell it from here well if you happen to watch the gut check project and you want us to have the ability to tackle a new subject the best thing to do is go to KB MD health.com escaping the health.com go to the gut check project show you'll find that there is the ability to connect with us and submit something he wants to tackle that's really how we the last two weeks we stumble across what we've always come across to talk about we cover so much ground he only would it be really cool we were talking last week about bringing Dr. Blair on Col. Blair onward and talk about TBI right now imagine doing the product light on the hospital's trauma hospital we have a food protocol for traumatic brain injury we don't have CBD protocol with DHEA or any that stuff when the beat amazing week ago were going to be a brain information diet your to be on the supplements and this is the protocols can happen that's the goal of this whole thing is to bring science and I mean a whole separate show would be talking about so fewer of thing which is a molecule and cruciferous vegetables like broccoli was it turns out it's really really good for you it's anticancer it's anti-inflammatory but when you cook it the enzyme can't break it down called the Rawson Ace and so like a little hack would be a chef we can sit there and say no were to put some of mustard seed powder on it and then it will actually convert it so you just made your broccoli or broccoli sprouts way healthier sure so if you ever get diagnosed with cancer and there's all these crazy studies about like bladder cancer and stuff like that when you do that like I would love to have a protocol food protocol what you're gonna do the Hashimoto's food protocols right there working have a food protocol if you get this venture headed that way no joke on the Chrysippus vegetables they come with them basically so you're blocking the estrogen correct correct yeah not separate magical inane speaking of preservice vegetables B cauliflower just last night my wife and I went to go eat pizza awesome pizzeria and actually make gluten-free pizza the crust was made out of cauliflower it's amazing what they're doing cauliflower now because it taste like great bread and is not read it all basically having a great Chris Arafat's vegetable while you're eating a delicious pizza and were hoping that in spray glyphosate on it so that it's a good skill LOL yeah non-GMO vegetable crust they taste just like regular bread is real know I love all of those cauliflower crust so it is delicious so we've got about half a minute here before she attaches going to join us in the next half hour just a quick reminder if you are watching spinning network EA know if you haven't you read to be sure and check it out there is also the no-show is hosted by Alisa Shakespeare Alicia Shakespeare and her name her shows no butts to big snow but stupid' TS is too big to get out it's a great show and we will join you in the next half-hour dry don't ill make you feel really good about yourself doing something good for somebody else if you'd like to do that today J DRF.org join them in the fight against type I diabetes J DRF.org it's something good you can do for the world.org hey guys Matlock the conservative cartel I like to take a minute and tell you about a new weight loss product that's instantly becoming part of the mojo 50 family it was launched by a Dallas area company when taken the good stuff and olive oil created a patented product that helps people control their appetite and lose weight 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dish authorized retailer now 800-570-6630 800-570-6630 – 800-570-6630 offers required critical location 20 from early termination fee any auto vein restrictions apply call for hi it's Doc Thompson for Matthew 25 ministries Matthew 25 ministries is one of the few charities all actually endorsed because I know them I've worked with him and I know almost all the money that you donate goes to help people go to M2 5M.org M to 5M.org and welcome back to the project this is GCP and Mayor Gregor joined by your host Dr. Ken Brown what is up check your ego at the door let's learn some stuff hey guess what we have now our second ever guest our third ever show so we figured it out third ever show you never say never guess we are joined to my right the man the myth the legend Chef Patrick Mosher hey don't you know that's that's quite an intro not sure I can live up to you lots not bad for sending DUI if you live in an Iraq chef Patrick does a lot of everything is chef obviously he also produces many the programs here on spoon radio he drives fast he texts and drives he doesn't sleep he likes his smile he likes to laugh Emily now I only text voice text almost and I just use a series command so if it comes in a garbled and funny blame Siri yeah well I just made it up at any another string I like you I drive lightning I got around on the weekends between here and there for work in any other time off I have so like the real work so doctors are unique persons are they have unique personalities I chefs are I think they take the cake and fruit upon the intended I've met a lot of chefs and a lot of sepsis patients and I am just fascinated by that lifestyle that you don't thank you so much for coming on we talked earlier about how Isabella went send us her book and last hour talk about how food is you are what you eat all health begins and ends in the gut and here we are we've got a chef with some serious experience you have you have done a lot if you think you and I worked at been fortunate to work all over the world I asked you can start my culinary career in Japan well as I started my culinary career career in a Sizzler steakhouse when I was like 14 what what kind scissors Western Sizzler is yearly wishes Sizzler stay cast so Sizzler was a pretty big Chad pretty chain back in the 80s and early 90s her hand so I would see I was the busboy dishwasher at the scissor state has until Thursday night came around I got Says that as a dishwasher busboy and apparently on Thursdays there is all you keep popcorn shrimp so the kitchen as he was like okay cool I'll cook so I was Sam's bussing outback that he can put 10 piece shrimp on any given play because it's all you can eat right there Arizona State football team and command after he simply teachers that your back in your ear like helping other iron in their back there, laughing at you because they get your percentage of your tips not only do the hardest job is to clean the fire at the end of the night but they get your money it only took me at six weeks to figure that out here and I was like man I'm the dumbest guy in the planet and and shrimp everywhere feared you yeah you know what's it's interesting that my first job in the kitchen sent me home smelling like seafood because leaders are progressing to see Sheehan seafood specifically every night was like a gate getting came to bed before he took a shower because your sheets are just a mistake in his previous but it is what is your family was your family a frequenter of the Sizzler growing up yes we reduces her in Omaha Nebraska so the salad bar limits telephone the logic of that was just going there my favorite item there as a kid was that not any part of the salad that the canned chocolate pudding for whatever reason quite nutritious goes right alongside the square chicken fried steak so this is what I love me with with your culinary chops that has gone all the way to Japan to learn this is where you start is frying shrimp and it says look I lasted about two weeks at McDonald's for that but I don't really count that right now I have nobody ever does now I was acquitted sure what I should do to food my father had a large garden but we lived in upstate New York and the town of Carinthia Corinth if you live there it's near Saratoga Springs Albany that area coming in the middle of steak and damn mind my dad's entire family all of his siblings except one brother lived it within a mile of each other on the same road and my grandfather owns a few sections of land on either side he had a dairy farm and then a large vegetable garden and my father attended at least an acre garden every year so we spent summers as I was like three on the pic means you're picking beans and snapping beans and helping mom put stuff in jar so she could cannon like a cat I am not sure I tell my first culinary job as a real job in the family right up your alley just doesn't work out well my grandfather's letter to cattle every winter and then we split the meat up but amongst the family charities usually did two more later but early in the winter the first big heavy snowfall made at and C have to string them the absolute peace how you gently say you killed him he just killed the bank and then… Our first episode we are to explain my background were Eric would go with his dad to register you and I would go to the slaughter house and my dad was a running neck and since that's what you're saying that let me know know it's not actually it's more like the ad that gasped AGI part O… Depart this maybe maybe maybe I missed my calling but before they can ask to get the animal there something has to be done so they hang it up upside down you have to climb up a ladder and you have to I was five years old when I was taught this my first time you to cut around the muscle up around of the maintenance and yet the tide because if you don't when the stomach elongates it's a geyser oh comes at the back is so that was my first real job for the family in slaughtering B was I got to climb the ladder and hi Taft about who I now I am I much rather have a mean as more or less permanent constipation makes total sense what you were drawing you like him to know where you already you know why writing for lent for several years plus the cost so after you had the exposure to the dairy farm and all the vegetables then that obviously is setting a foundation for you to get into food you probably had no idea that's where your leaning but i know i did and i really my mother was a great cut my father was a good cook a very good cook and her whole family every every that revolved around food okay so as i got my father died very young i was six years old he died to great cancer at 47 while yes and dad back then there was no really no treatment by the time they figured out why you had back pain is been much over and anyway so but i spent a lot of time when my mother cooking after that – i just i just picked up i really love food i did i i was fortunate enough to move to germany my senior year in high school and the family that that that i lived with that hosted me was very generous in that we had to get other countries in and dine on some fantastic food and food as a way of life for them and in germany is where i learned about minimalism in the covered you know because they have dorm style refrigerators don't have baked refrigerators are slightly larger than little boxes you have in your dormitory in the shop every day every single day at least once a day to shop as it was for your bracket was delivered in the morning fresh while that's pretty interesting. it was awesome so i just a side note growing up and watching my grandmother cook my dad's mom she was she was fantastic i loved her fried chicken as she fried a lot of stuff but for some reason back then she still remained skinny but she and i don't know if your mom or your dad was like this my grandmother could flavor anything to taste terrific fried chicken chicken fried steak vegetables etc. but one of her trademarks was to always cook with a cigarette hanging out of her lip that was flavored building with burn ashes in there as well as i think that she saved all the different kinds of meats that she brought in the oil and in different folders cans fish oil and that chicken grease etc. is it something that you also did not say new york yeah you don't weld eventually i think had a different flavor and if it will will start thereby produce because we have burn pile of year trees that would fall with a lot of property and we burn on the actual garden so what would and might my father would rotate back and forth into plots so each season the previous year's burn pile become the new garden in city dias content right the potash well – content was really high so a lot of minerals and i mean it's it's amazing how healthy the vegetables are when you do that you people used to take the ashes from the fireplace and put them into the burn pile into their compost deep sure we don't anymore but that is not right there was just fantastic for the flavor and the freshness of vegetables but my money as she skewed everything okay you accept what you call it swiss steak was boiled whatever lien beef steak she could buy it was the cheapest cut with a bone in it and smothered in them tomatoes and garlic and then she broil that the oven it was actually pretty good – he sounds delicious compared to what were some of the first part of the show what i'm thinking is that you know smoking has a lot of it is a carcinogen known as benzene but we should do is see the chemical structure similar to benzene to add that good childhood flavor that you're missing the smoke when without getting the cancer yeah yeah probably so he can get you can put winston cigarettes into the mass spectra shouldn't even pops out to charge me figure out figure out what fruit or vegetable has a similar molecular component near benzene time answer i'm interested that i'm really curious about that this is a fascinating science for me and i'm thinking i could just as i could change my restaurant consulting business to just be menu consulting based on this and take the elevator TOoh yeah absolutely this is the kind of stuff and we wouldn't be talking about if we were preparing for the show i was just i was just a deal try to think of okay what's a really cool thing we talk about i have to sciences up i like it i'm a nerd and i'll probably try do this with every single topic that we do find something that yes really fun oh terrible that would be really cool so you're sitting there sobbing for your dispose of this great organic before organic was cool you guys had a mechanically warm touch poor poor alright so what happened after that we moved arizona which was a whole different thing i learned about spicy spicy foods right my first meal out in every week and eat out a lot as a child very rarely maybe once or twice a year at the most we went to this little mexican restaurant between chandler and gilbert arizona which are now massive towns that have grown together but then they were just very small towns and that limit its cost is something this little mexican place and i had a chimichanga's mother eating spicy green chili salsa and i went ballistic it was it was done i was never anything but eat tasty food again and and and and not healthy necessarily but flavorful food and that that cannabis bondholder you and you live down there is i guess i was in sixth grade summer and allowing a nice set of a few years so then you you progress through graduate and then you end up oil before you graduate you worked the sizzler and then how did you decide that food beyond being told they arraigned a danger going to do popcorn shrimp something you want to pursue and deliver to people to make him happy what i had few other jobs cooking after that but what i realized is that no matter how how cash strapped your family might be there is always food in the restaurant and she works there used to get some of it for free sure so i think that was it i think mentally i determined never be hungry again right and i just parlayed into into a career but i really and start cooking full-time jobs in japan is working as an interpreter such working as a copywriter start get some interpret good job in japan like writer i did for chemical trans tech international they were a check technical translation company the parents of a friend of mine had come to united states to go to school in eighth grade and stayed all the way through high school they owned and ran the company in osaka japan and he invited me to come and work for them after while i was acting in college time well so i heard you speak german and you also speak japanese type hello, so wow so this is fascinating so chefs or super intelligent people that know i'm serious. many of my friends are chefs or people of extremes share the nar that is fascinating you speak japanese german english to work and back doing appetizer version and it was as fascinating i love you and japanese chefs are so meticulous they have the waiting approach for japan and she had a proverb that defines through japan and it's it's it's that the only the audience at is actually it's it's not just food it's the food it is the substance of the universe right so their philosophy is let it let little seem like much as long as it is fresh and beautiful let little seem like much, as long as it is fresh and beautiful so small portions very ornate and well garnished very clean and seasonal seasonal is the key word there and typically local all just too far ahead but i do remember one of our previous conversations you did say that you were with the noble as well greg i did work for number for number years i actually i was the executive chef and that helped open a restaurant in aspen last month he said that's his last name and then i was fortunate similar location so in a minute i'll imagine all those principles that you're talking about probably carried over to the live presentation the food yeah you know honeywell there's a whole another layer there and he he lived and worked in peru for a long time and he was fascinated by french cooking techniques so he took these japanese base ingredients added the layer of the like infuse the flavors of's of peru and chile and then to add that to another level by using french cooking techniques and just phenomenal stuff while yelling at ocean would say there so my family were huge asian cuisine fans all of it our favorite restaurant is actually japanese restaurant in plano we go there at least once a week really i mean you can send him a plug – or llama iam a check now yeah we have the it's just unbelievable it's it's it's it's good and sensitive i think is very very traditional japanese food had told me our waitress is always our waitress so we just sit around and through to start showing up that's what i love the methodical just this is what's happening it is predictable it is well and it's thoughtful thoughtful yes so it here's a really interesting cultural thing from japan is a great book called mino because with some the dip the anatomy of interdependency okay okay describes her whole culture one of things in japan and when you start a sentence they finish it for you like ice to teach for this guy jenna ricci he had two small children i spoke in my itouch spoken english i taught them english and japanese speaking is my second day speaking with so gimme a break he would call in and he would say i think you and i say yes he is jonah lychee desiccated and will mean this is generally key and he just stopped and i'm supposed to finish since you must be calling about but i wish i didn't know that right some just like okay hi i just wait for him to say something but eventually you learn it's like him japanese interject a lot they say hi a so they stay in there what they're doing is they might say yes oh is not so there interjecting to let you know there listening actively listening even if they say something in agreement it does mean they agree okay i mean yeah but anyway back to the point i was making is when somebody hurts a guest and some house for the first time in you they say would you like some coffee and you say yes they don't ask you how you want to and they don't bring you the things to put cream and sugar in it they automatically put in cream and sugar because the first time as a guest in their house you should not have to think about how you want your coffee served from then on you can just make your own but the date alleviate the pressure from you even if he didn't want it that way and you accept it graciously because that's the generosity they're getting you to relieve you of the pressure of having to say would you please fix it this way oh wow cool yeah there's so many layers of complexity to japan's culture that's all that's a month that well that's a whole series of shows for next year while even a chef for a long time what would be something that in the year in the realm of being a master chef going from the being taught japanese in the office it was some french i carryover what what take your take you to your favorite style of the play setting now i thinks my love simplicity and food such il might my mother she stupid a lot of things but were really great fresh ingredients if it wasn't steered my father was a big fisher and fishman and hunter and so we had a lot of wild game he had we always had a ton of venison backstrap a lot of rabbits a lot of fish so everything is very simple when we went camping my father did take stuff for dinner he would hunted or efficient while a fish will also describe the pressure then a joke yeah yeah tv show now yesterday i really afraid survive as their grills at this time you shop for breakfast but you a loser it was very simple food so you take out lemons potatoes salt pepper and onion and so if if you cut trout then he to be slice of the potato and onion stuff inside with a couple of wedges lemon slices lemon salt-and-pepper and then wrap it will a pat of butter there wrapped up in tinfoil turn on the fire you know if there is other game to be had than it was you super simple or boiled potatoes and simple fixings and then salt-and-pepper on one of the game and so these really clean simple flavors for me i really would identify with any candidate that you can't really elevate that sure with a few adjustments but really being able to identify the main component like the center of the play item the protein if you can't taste what it's supposed to taste like i'm not sure what the point is sure will will today you just unit of joining us because you had just left a gigantic gathering that you are asked to basically help map out how do you know whenever you have so many mouths to feed that you know i'm going to be able to put together this coming plate to serve this this type of convention or do they give you parameters of what they do and don't want hello hello yeah so i'm to make so many development or menu yeah menu development or menu selection for any large parties very very critical because you have to think about if you have have multiple selections especially then what is the em what is the time to plate each item on a plated is his buffet mean all that comes into play i've done parties as large as 2100 people we get i work for a company in houston and we get a large plated dinner for the md anderson cancer research center answer hospital is so wheat we did 2100 people seated but the preparation for that took a week but nothing is really cooked until needed some things are made today before but not cooked until that day but all the proteins like all the tenderloins all the seabass so there are 1100 pieces seabass and 1400 piece of tenderloin while the kennels were hole we had to cut them i i had cut the measure but yeah that's that was we we all that gets cooked in ovens lined out inside of this big giant makeshift kitchen that's 20,000 ft.² and then we had 16 ovens in there like big commercial ovens do you feel like that your principles and how you wanted to live you want to deliver good health for people through the way that they eat that sometimes you get compromised because it gets so big yeah i mean hat so there are ways to dragon simplicity is number one pitcher and then limiting your your menu to items that fit your your desires and what you want to give to people and bring people in the hospitality industry you can't compromise that so only serving things that you may look for an alternate approaching so if they couldn't afford the that tenderloin we could do something like baseball saker you know tri-tip or something like that site to get a similar quality product just not as expensive i think that's that's part of the creativity that chefs have to work with nowadays is planning for and like an upcoming season we change menus to the four times a year restaurants so you're primarily doing this right now for your work also i do that yeah i mean ii will this is your this is my baby i want to get into that as this is how did you end up here doing a digital show but friend will talk about sorry love you so much anyway but the planning phase is really what it is yet to be very organized and there's a science to you know how many pieces everything you need what the portion sizes and what your standard batch size recipe see to scale that up although there can be complications or because salt doesn't scale directly other some other components like oil don't care they don't scale you know it's not exponential it's not like six times this equals that know if the scale somethings back and skipping some something so what i love about this is that you're talking zach the kind of leads into the first part of the show but this is how i cook i view it more as a science and i want to know what this and you're like i don't i didn't have a grandmother with a marble light in her mouth inside yeah so like now at the stage like i have a really i really enjoy quickbooks us all so excited that isabella went something cookbook i got bobby flay's cookbook which is that one on the quick side note is that the ill be like now add the sausage you like got it and then you turn to page 20 like that sauce is 50 and so there is a very famous book book called the the reese's gag gastronomy great and and there's another one by written by august escoffier who who really founded modern french cuisine right in the way that they cooking french kitchens and what happens it'll say like a cookie was a shock which is its sea scallops with marty athos or something right when he says cc the scalp recipe and it says okay now seat recipes 42 918 when you go to the buyer the year but is like 97 steps and then you have the mornay sauce is like when yeah whatever whatever size you are making is like 467 steps and you can't make it you can't story cold as beheld hot and fresh i mean it's just it's so complicated i was like okay that was go back on the shelf and maybe never adult ever dust the back off again i read it religiously 1000 cal you have a terrible cook and sometimes whenever i want to cook and i'm learning to tip these says certain things together if i see that there's a whole another mess of steps to make one ingredient i usually light which is not have any this it's it's changing out the menu the item is off the menu are going to do something well and that's part of the so i'll say on the show sometimes i don't i don't do show prep well i crept much better for life in restaurants than i do life on the radio sure and sometimes i get half with your essay like this make sense now that in the night so i spent a minute research demo i did next he read the recipe i just assume that this is what they meant because this is the type recipe so pre-reading the recipe knowing the ingredients in the methodology they're coming up are really important during the prep work will before we end up rounding out the last is our since you are one of the main producers for the spoony digital radio station we will get to why you ended up joining spoony radio etc. but tell us little bit about some of the other shows that i can and i are just now joining cemented lisa shakespeare she she actually has a her show no butts to big is phenomenal she's very energetically young lady but she had some health issues and she owns a company called total cluster fudge which is not so there's another new and called some monkey butts but that one is is the healthy version of the desert she does now for total cluster fudge and as this dessert manufactures she had to stop eating the things that she makes in the said these are carried in them convenience stores and cosco and there sold over the internet and at some restaurant seasons well which which is great she touched details each watching three healthy tips and tricks to just we held your life every day and along those lines is gwen rich of the rich solution solution yeah she's just stage iv cancer for the last 6 1/2 years she's why she looked way past her expiration date as she and her husband adam say that she was misdiagnosed for eight years before that so she gives tips on eating mortgage with more nutritional value more healthful and how to if you have been diagnosed how to prevent being diagnosed as best as possible that's the very first show i did with dr. thompson you rest his soul you are supposed to sit on my show he's an undertaking to get here early and you shall prep well i love this didn't really into it like that we can do so we can include the chemistry can say how do we make these things healthier like increase yourself you are paying and stuff like that euro lutherans all these big words that basically you can eat well and you're really healthy why don't i mean we have room for play marsh joseph you want to collaborate that were ready to go yet get so we have you have a minute here for you to wrap this this part up so if you're watching now stay tuned you can always check out love my tummy.com/spooning to pick up electron teal caving de health.com he can pick up your kb md cbd next half-hour going to talk to shift patrick little bit more about not just what is done as a chef or what brought them to spoony that also you also required to experience with cbd chef patrick and told us stories night shift well you know this is the only 24 hour take anywhere platforms dedicated to food and fun we're spoony this hour from townhall.com, the fbi joining a criminal investigation of the faa certification process for the boeing 737 max a jetliner the blazer crash since october killing more than 300 people there are a number of inquiries getting underway including one by the transportation department inspector general and another investigation by congress in the wake of the mosque shootings new zealand's government banning military style semiautomatic firearms in high-capacity magazine prime minister jacinda arter and says additional gun control measures in the pipeline's motor began entrance to look at issues around licensing issues around registration issues around storage there are a range of either an image that we believed to need to be night and it will be the second tranche of reforms yet to come following a visit to ohio today vice president from in michigan in grand rapids tonight the president will address supporters at a make america great again political rally's trip to west michigan follows a daytrip to politically important ohio yesterday where he reminded factory workers about the economic gains during his time in office with 2020 democratic candidates already crisscrossing the country look for president from to also be traveling to states that will be crucial or his reelection greg clugston at joint base andrews in maryland national guard troops been called in residence being told to stay inside after elevated levels of benzene were detected your houston-area petrochemical storage facility that can't fire this week several school districts also canceling classes for the day citing bad air quality the national weather service is warning the plotting and parts of south dakota and northern iowa it soon reach historic levels floodwaters have driven a lot of people out of their homes, several midwestern states wall street the dow up 57 points the s&p seven point tire one of the stories@townhall.com if you are trying to quit drinking or doing too many drugs listen to me you don't know me and will never meet i had a problem like you want i drank and used a party a little too much till he got out of control and almost ruined my life i realize i needed help to fix my problem before it totally destroyed me if you tried to fix your drinking and drug problem and you know you can't do it alone you need to call the national treatment advisors they'll immerse you into a 30 day program to replace your old habits with new habits and 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payments down to as little as $25 a month based on what you can afford to pay 800-709-4395 800-709-4395 800-709-4395 800-709-4395 six booty food and fun okay we are back for another half hour of gut check project it said year three join here with your host dr. kenneth brown this is awesome so this next half hour should be hilarious because were going into chef stores but more important on which we don't do the job we have are from producer marie rieger how we doing i just cannot send it down alright we have also our guest here and i sent to patrick when i speak to eric when she speaking to micah when i got like this to make sure i keep okay so there is something i have instructions already well so for all of about what one hour is so so you start doing this we have this thing guys have this thing i have to always tell people to come and see you keep the microphone close never looks at me with disdain like like i know guys have this phobia about putting something phallic looking right up to your mouth and show a smile and wave smiling way to be okay :-) how these on an emory better nothing ice not well we left off this last half-hour basically talking about your journey on how to become a chef and where you been we learned that he spoke japanese and german hello the spanish and if he traveled and and it the age of five was able to close a cow: yes tied off time off dear: close to a man climbing up the oh my goodness that's like everything but the last half-hour makes me just feel bad about myself wanting you bring your homework for kindergarten and also to maybe climb the cow instead of a ladder knife in her hand and run around your neck you will tell us a little bit more about your journey now to rejoin here the next for some in the next half-hour you have moved into not just shiftwork but you've also been exploring cbd so i know you got a story behind it what in the world brought a chef is now on a digital radio station to explore cbd well just because he was my was my hero back in high school not really know because my my mother died in a diabetic appeared my father passed of pancreatic cancer and my mom died 01 and about that time i actually heard about that they discovered cbd and that was mid 80s i think when they discover that they were really starting to realize that while they made a big push medical cannabis was now legal in in california working on colorado and so i was just fascinated by that how that worked in the body i i don't like the psychotropic effects of of kinsey's audience is the antiaging specific because you know as a chef i always want to fill a coming control yeah that's that personality so i i really am i never really partook in it but when i found out about that that cds and how they affect the body i got became fascinated and so i just i got involved in a business that was related data in and i'm actually a partner in medical cannabis related business and in an tactic, and in massachusetts but we do a lot of really high cbd extremely low thc strains and stuff like that that's cool so my my experience the reason why i'm so into cds that you know i kinda had a heroes journey where i saw some incredible fact did you have anything like that happen yeah so i you and i think i cacti brushed over that little bit with my children but so my son and daughter have a i'm a 20 else on an essential daughter my son was 12 he kept having these ankle injuries playing soccer and he was trying to get into that a lick big development pool and kinda girl that way anyway so about the third time we took him in for ankle sprain in like six months we took him to specialist but i trust and she does i is really long high arches and his ankles are kinda rolled out he think he has cmt like cmt i don't cmts but so charcot-marie-tooth syndrome causes degradation of the neural pathways between and in the in extremity skin it causes type of neural what neuropathy peripheral neuropathy measure and what happens with that and that that the small muscles start to weaken the bone structure starts to deform so a lot of children or or adults with that with cmt will have like a limp wrist were that the wrist turns in and out a little that is truly painful it can be and will actually ache it can be painful but in this case you have to start to lose sensation so my son at 12 is about between 17 increased 18% deficient in the pass-through of you know the impulse from elbow to fingertips and needed toe okay so after testing their likely something that you can do just keep them strong become a fiscal therapy there's no treatment for its tenets genetic so over time my daughter started getting injuries and my son went off to a 2 am text dammit 18 and as as he was like a 18 a week i think his birthday just to curry start school and he was competitive tennis players i know you have a tennis person family and when a debtor where the antennas from the bottom that's right that's right that's right state championship anyway he was having ankle injuries there so when he came out of that that program the only thing i found i done thousands of hours of research looking for anything that could help them in the only true they say is stay strong be active don't get fat that's the three ways that you treat yourself boxers there's nothing else that they've known to to cause any actually to delay the effects of it if if if it is to progress further than staying strong and healthy and so he was very active but i found this this article the cds actually on that while website that i shared with you called echo connection.org and i did some reading i called some friends i talked to guy another dr. physician california anyway so i just i order my said look you take this twice a day and let see what happens and not only did his focus on his schoolwork away up and his grade started to get better six months let lesson six was later we took him to the texas anam research facility where they do studies on neck back and spine injuries but they also do some neural testing and things like neurological testing so first date they deliver the jet they did not look to the genetic marker on that wednesday we know he has it so what they did do a stated a more comprehensive testing on the neural pathways than he had originally the first two times and it was back to hundred percent so now before he was down he said 1718% he's probably got 25% by the time we took in it by the time he went at this time to be tested so i'm gonna kick that up and break something the results we got scolded for i now i do not migrate a hearing and i just want to be a rock star please not constant today this is my season recap though your son that the biggest change in imago simply does adding this evening i was the only change made the only change that was made in his diet and i was very very he's a very clean eater he actually started cooking his own food he was off his meal ticket at school and he saves on a very at enthusiastic weight training program that he designed himself and so but that was the only thing that changes diet and exercise regimen at all we will be look at this if you realize that charcot-marie-tooth syndrome affects the nerves and we know the cbd of the endo cannabinoid system is deeply rooted in the nerves then when that you start decreasing that inflammatory process and what i love is that you just said the key here is to changes.we know that food can be just like medicine and it can actually help out so here we have a college student it's on cbd and eating his own food not eating on diet plan that's amazing and he been well i mean an end at home he was a very clean eaters while he's like the one person the family does like desserts he won't eat cookie dough like anything with frosting on it very low sugar intake refined sugar like fruit didn't live on it measures none none that i'm aware of it i would like to ask a question he has them his hands and feet are always cold but he does have hair side of the follicles can't really thinking that you can go here with any without any ennui that i thought it might be circulatory service account because there's little knowledge syndrome 90 there were to get a little cold and you your it's an autoimmune it's component of autoimmune disease were your arteries sort of clampdown its interest is also a warning sign for autoimmune diseases top bring us more yeah and angry people all over the place have nods yet it's not uncommon you say it just kinda matter-of-fact all of a sudden you know she had 100% improvement there and you know it's one of those things where people hear the stories and you feel like you're being sold something but you say very genuinely it's like what's this thing that a difference in his life and that's why people are so passionate about cbd gasoline and like i have nothing to gain by telling so i don't not financially sure i'm not rr production facility is even open it were still the middle building it in our tech companies $14 million away from making money so if you want to join in the future of the industry go ahead but yeah there is that i just tell my story to share with people so what did you do when you did when whenever he told you how he felt and you knew that it was a real difference it wasn't it wasn't just subjective it was an objective improvement for him you mentioned his grade you mentioned his his mood is energy etc. so those are things as a parent i know that you would be able to easily perceive what did you want to do that information right off the bat and how did people receive it when you shared well immediately i started taking the product i started my daughter I and so because i want to know the effexor and audiology i for someone who is so well versed in the in the in the industry i don't take it on a regular basis i don't know why i have this it's just it just falls off the plate with so to speak when when i look at my daily supplementation but but so i put my daughter on it right away and then i went to a meeting with some people that were interested in cbd's there is a conference going on and i spoke i gave but i just told my sent store i told my story my son story from my perspective and then and i just type i have been an advocate ever since while we all have kids guessing your kids suffer from anything just well there's no way to ike i can't that's got me held that the greatest loss of for anyone ever is to lose a child but even when they're ill i mean or they don't feel w

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Inaugural show!!!!

Play Episode Listen Later Mar 7, 2019 117:13

Welcome to the GCP, your host Kenneth brown, MD along side Eric Rieger, CRNA. Dr. Brown introduces why he launched the project and where he wants to take the project in his journey to bridge the gap between medical and natural science. Check your ego at the door and listen up to the GCP!All right welcome to the gut check projects I am Eric Rager and I am joined by your host on the object project the board-certified gastroenterologist Dr. Kim Brown what of your own show while so we are now on the gut check project this is the inaugural show John just thinking that we been planning on doing something like this for a long time with this incredible opportunity to do it with these great mentors Jeff Patrick and all these other great guys here doing this incredible production value now we have a studio on thinking that maybe our tagline should be something like the gut check project let's all check our egos at the door and learn from each other nothing is off the table nothing is off the table in fact we have a bunch of stuff on a table so this is our first episode people may say get check project sounds great who in the hell is that guy he says he's a doctor but is not wearing scrubs want you tell us a little about yourself Dr. Brown so my name is Kenneth from a board certified guesser neurologist I do want to back up just a second and explain exactly why were here because of a few weeks ago I had the opportunity and the pleasure to come and actually be a guest on Dr. Thompson's show here on mojo 5.0 chair and then we came over to spoony radio and we had a great show you can go to the YouTube channel take a look at that and unfortunately a few days later he was actually tragically killed so I just want to pay respects to that and say thank you we wouldn't be here without him I had such a great time with him and he's the one that explained man you you can do this you guys should have your own show it's really fun so unfortunately you know we lost as great guy and he's the he's the real reason why were sitting in this particular Studios I got so excited hanging out with him so no doubt yeah so as I said my name is Ken Brown board-certified gastroenterologist I'll give you almost give you the whole story this probably led people to don't know anything about me so I probably don't I'm I was actually born in Lubbock Texas that's right big red raider big red raider briefly parents moved almost immediately to Nebraska so I consider myself more of a Nebraskan and I went to medical school Nebraska my fourth year of med school and scraping ice off my car and I just went now done with this move someplace cool and warm and I just ran to Texas and so I end up doing the rest my training in San Antonio and became board medicine certified in internal medicine and then gastroenterology and since then moved to the Dallas area Plano Texas have been practicing astrobiology for while too long now capture a good while not a rear end yeah yeah a lot yeah we do I know you know I may, but Dr. that's why say nothing is off the table were over here and so I have two kids I have a Puerto Rican wife so we speak Spanish in the house I worked very hard so that my family can play a lot of tennis and world spoony radio we got chef Patrick being a mentor here and as it turns out my family's total foodies we love sort of bonding around foods was a perfect environment when this diner setting to great way to launch the show so I will ask you Eric super fly reader think that's your juror yeah yeah now would I? My parents always told me to find the esoteric I know that you are a child actor would breathe. You did you are a rodeo clown right and then your male model yet and so what if what you doing now besides help me host the show well I was in the middle of inventing a mechanism to create high temperature ice cubes and I didn't really work out so I was a melting every time there was nothing I could do but I will say that that led to me deciding to become a cRNA or a certified registered nurse anesthetist in and back in 2012 and in meeting you and we've been I was your anesthesia provider is that you are working in gastroenterology and course I work get a few places outside of the G.I. clinic to deliver anesthesia as well but I also have a wife and two sons they are not into tennis but very much into a competitive basketball and both in high school now and so that basically led to me working alongside you and next thing I know just like every aspiring gastro neurologist and anesthesia provider I ended up on a podcast there we go so you so it looks like your tRNA you've got kids that are heavily involved in basketball trip I do believe you work for another company called trying to let you dear to my heart which will talk a little bit yeah and you even have worked for a particular company and still have a part owner of that right yeah I am a small owner of that at one of my best friends I grew up with in Gainesville Texas his name is Scott Willis and several years ago he just approached me and said I'm gonna start to kill company by myself unless you want to help and I knew nothing about an essay that sounds great let's do it so we asked people for money with a like to invest into killing people like investing in alcohol and he back in 2012 when I met you he launched tequila 512 and that's based at Austin and they slowly are going out as an organic tequila and he's a doing quite well very excited so we both are involved in several companies this what happens when ADD just meets momentum and just keep going and we decide yeah let you several podcast now beautiful studio that has no great mentors like I'd mention like working I have the ability to have his high production value would get the cameras this is stuff that we could never do with you and I have talked about in the pockets before but I'm so excited that were on spoony radio right now to actually launch this weave we been involved with a lot of great people of last few years I but I've done a lot of podcasts without question yeah and we've made some great contacts and basically all those guys everyone the practice we got on guys like Chris Presser and Rob Wolf and I could just name we've Done Ben Greenfield Tunl., Park as they've all been so clueless and kept in touch and said would you guys have your own show we can do this I would love for spoony radio to get big enough that we can start flying these people and having great shows and talk about different things that's my ultimate goal with this so no support of the shows will be really important I would say with the mentorship of Doc Thompson in the course in his wake you still have Patrick you still have Ron you still have that Tom and all the company really picking up and pressing with spoony radio that it won't be long until that happens and you know you do doesn't just stop at those that podcast that you mentioned in your event on know you even on the wellness mama you even Rhonda Karen Fitzgerald the exposure that you had there from the going on all those different types of podcast I think is well this is really eye-opening so tell Silbert about why are you doing this podcast after doing all of those podcasts every time that we have the opportunity to go on with such great people that were really established if they had like Melanie Avalon okay intermittent fasting I went on her intermittent fasting podcast and because of the research I did for that now I practice intermittent fasting so I start looking at what everybody's messages we look at Ben Greenfield's bio hacker love the stuff is doing I looking everything that he has going on that's all, now I have a infrared sauna I got a vibration plate I got I'm doing all the file hacking because of going on been showing talking him but all that stuff and you know I essentially I read Rob Wolf's first book I have read a second book yet but his first book of the pillow solution great book I realize oh my goodness I I'm wanted to change my diet here so that we can I can be more pale you every time I go to show Chris Kress or the compressor Institute holy cow fantastic functional medicine doctor I'm a traditionally trained MD and honestly he opened up my world to the aspect of treating a patient holistically and working on their lifestyle to make everything better he was the first person that I got in close contact with it was actually talking like that so every time we do want these podcasts I grow from it I become more robust I become a more holistic I've just grown from being a traditional trained MD to more of a functional gastroenterologist and I really want to thank every podcast I've been on a map to get some really fun ones with sexy brain the author sexy brain right that was a superfund one sure it's just her whole philosophy is that you have to as we age continued of sexuality in promoting that protecting the brain and you start seeing certain themes what were seeing is protect the brain in my motto it's all health begins and ends in the got pregnant you get is unhealthy everything else is going to start breaking down on you so we can protect your gut and we know we can protect your brain and if I can get you to sleep then we know that all the pillars of health are covered and were going to hopefully bring all these people in to give their expertise in each one of the spots that's gonna be the real goal of the show is to bring education that I'm out there talking to people with after I would do is show I was shocked at how many people would contact me from all over the country if not all over the world and they would set her doing this podcast you mentioned this one thing can you expand on that a little bit more like while they're emailing neither do this I just on the podcast that was it people try to make appointments with me because they were so frustrated that their doctors were not listening to them and here I am learning from authors we have bio hackers we've got athletes with professional athletes that we been talking to I feel like with the whole point of gut check project is check your ego at the door let's learn from each other and if we can learn from each other and I can get that message out to more people I truly believe that we can change the landscape of health someone to say something here I've known you for several years so I know and I seen your patients come through and I've seen where a lot of this genesis of new ideas and new applications of what you want to do with your patients and how they begin to receive it because we see them in the G.I. lab and we seen the from the very beginning and 70 they begin to feel better and they talk about not only how is it affected them but how they want to share that message with their own family and then lo and behold I believe the first actual podcast that you went on he didn't have any warm-ups you went straight to Chris Chris or because we literally did not know what you're getting into and it that point you went on and really it was less than 24 hours it was published it suddenly phones email website traffic on and on and on people began to reach out to you long outside or far outside your nucleus of where you have your practice and in North Texas it was multiple states tell me what about that what he did do for you to recognize what that platform is doing for you and the message that you had for people to get better what that told me was that the people that were listening to that podcast had a trusted source there was no agenda it's just somebody that they trusted and they listen to that and they wanted to continue to believe in whatever he was sent okay when it's a podcast you have the ability to subscribe or not got stuck in traffic and I just pops up and it does this this is what this shows going to be about I want to talk about stuff that I truly believe it also I want to talk about things that I have seen success with I have a lot of patients that have had tremendous success of doing diet changes supplements no change a few things work out routines and I get tremendous benefit from that and none of that other doctors are talking like that will the platform is bigger than this we have to get the word out when I learned something I want everyone to get better so what Chris showed me was we just jumped right in that that medium is so powerful if you're honest if you're talking science if you're backing it up in your bringing guests on that are doing the exact same thing that's what I want to do with this I want to bring typical scientist like that to talk research to help out with that kind of thing so somebody has a question let us know hey can you talk to us about antiaging will reach out to me that I have goals and aspirations Peter Addie as I'm a huge fan of him if you don't know who he is he is an antiaging specialist pseudo-roots I get some other interests also jujitsu and things like that you know eventually will have some you know Joe Rogan on the show that's my aspiration to show off you may be a little much on the first show to say that but I think we can bring it work a merger bridge the gap between traditional medicine and functional science or natural solutions okay so you just hit on something else in another room to touch on eventually and just so people know the idea behind gut check project is every Thursday from 9 AM to 11 AM central central time we will stream live and in the course will be available recorded after that but every Thursday that's going to be to get check project and while we know that that's all going to do going to have basic themes every single time that we do that and what has enabled us to D's to decide Dr. Brown how to reach out to people on this medium is that he does want to bridge the gap so that something I know they were going to talk about the next half hour but what is it to you to bridge that gap what is that mean specifically because I know that it's between medical in natural science and the applications of the two what started my practice I came out of this the classic Midwestern medical school training center and as I've mentioned of learned a lot there about different disease applications in different to the disease states and then once I start my practice I started doing clinical research and pharmaceutical products that were being developed and it was fascinating to me I saw the whole process of how a drug a compound starts what they have to do to get it to market how they have to get it FDA approved the studies that are done and I did those studies there's limitations set it costs to hunt them on a ton of money and you not to spend $30 million to get a drug approved if you're not, stacking the deck your way so realize that there's we need research when I went to medical school it was the dawn of the evidence-based medicine approach or so before that it was always you know you just had this mentorship were the guy in front of you taught you what they did and so on that was the Socratic method of teaching now all of a sudden were talking oh we need evidence-based medicine that everything became evident the numbers didn't add up no go no go yeah will guess what if you get enough money those numbers can add yeah something you can buy some go you can buy some go yeah and that's all that's what I was seeing so because of the traditional research that I was doing I actually was able to find some holes and that's how we ended up developing a product called archer until my baby very close to me if you have any washing you can see this is arch until I saw green packaging will get into that a little bit more but bottom line is do me a favor everybody go to love my tummy.com/spoony spoony SP 00 NY show some love you we want to support this station not just for us but also word trying to make sure that Dr. Thompson's vision keeps growing keeps growing and that's one way to do it is to support the sponsors happens to be that I'm honored that my own company is a sponsor and still offers the 100% moneyback guarantee and they did it before we're given a show that's what so cool yeah oh yes they did so props through our CEO Chuck for taking a bit of chance there and hopefully will continue to grow subject so we have talked over the bridge again you've obviously hit on the fact that you are the creator and a researcher behind the development of John Teal it is a natural solution you did do testing on it for IBS bed legally here in the United States have say bloating ironically enough though when the product was invited with open arms by the intervening Canada what is it we can St. Canada a as he cracks a Molson so yeah it's very fascinating we just got our NPS and NPS the Indian NPN number in Canada and in Canada there is a very different than the US they actually they don't want you to talk around issues like what do your studies what is show what is it show what is the disease state so in Canada were in Canada our new labeling says irritable bowel syndrome in Canada and not have to give some props out to I I do a lot of hemorrhoid work and the hemorrhoid work the company that I was using CRH medical actually called them this week because like how we market in Canada how do we team up to do this as it happens the the the products and not try to help with bloating and constipation which ultimately bloating constipation causes hemorrhoids and liquids team up so that's another thing that will get into but it's fun note launching a different country different culture try to feel what's going on so yeah so in Canada we can say irritable bowel here we gotta say bloating and the vague terms what were all looking around and shifting our heads because this is our first half hour ever the yeah of the gut check project but what I can tell you is you view tuned in so far hang with this for the next hour and half we can talk a little bit about what it was for Dr. Brown to research what it was about the creation of John Teal where he is on the ideas of the cannabis industry natural naturally apply medications on and on and were still going to get into some of the fun stuff in fact what's is all God's name you can guess go ahead and email us the first 17,000 people to email this will get a green too thick yes so the inaugural show we realize that we needed a mascot were calling this guy got see he's up frog on a toilet with a phone correct and I figured that if we had somebody here gutsy that if somebody had a question I couldn't answer we have this little guy call up an expert because of all the work we've been doing I do know a lot experts do know people there are experts in all kinds of things you have an expert next week were to have an expert next week that's correct and probable have experts every single week on topics of anyone has any topics they want to cover KB MD health Pat Sajak came out with stage IV pancreatic cancer to wrong I'm wrong with that database Alex Tribbett will extra back they I watch a lot of TV sound now you did not ask it in the form of question here you did not so it's very sad but I cannot today and I started thinking I was like oh my gosh I had people texting me all morning long hey what does stage IV cancer pinker cancer may not like them when my partners I got to partners or pancreatic experts that will tell you everything about that that's what these guys do we have a pancreatic surgeon that I work with all the time you see a statement Naomi Joshua so he was so brave he did it and is very is very professional tone and even through to a joke saying he knows he's going to survive because he's got three years left on his contract and amp and it's it's of incredibly difficult thing to go through knowing that he I believe is 70 years old is he really saying he looks amazing he looks incredible after all those insults by Sean Connery through still looks like Eric and sucker Trebek had no eyes shut up saying I live and the yeah the Jeopardy's lead with that will Ferrell and all and in the Sean Connery and Burt Reynolds impressions Ella some of the greatest things when I saw that that he actually a bank of cancer for sale but it was S&L yeah gotta watch you not actually watch Jeopardy but the first thing I thought of but that's good for him for embracing it and things like that bring awareness so if there's anything like that going on were delivering those experts people have questions let's talk about different things that help prevent that like healthy lifestyles and really big in the diet various diets and all do them all one of the route you want to think is going on these various podcast meeting people I do a lot of lecturing and Saul go to like Paley why faxes yeah right one of love that come from great conference great conference and got a note the opportunity to actually lecture this year there will probably be lecturing next year also Michelle Noris called me up and said man we really want you to come back there's a great example of the ability of diet to just completely change people's lives Mediterranean diet in no profound anticancer diet and you were to hidden all that stuff check but it's not just going to be my opinion it's going to be backed by science we can sit there and talk about it working to try and bridge that gap like we mentioned and if it's complex conflicting with complex something that's really complex as the Endo cannabinoid system the ECS and in fact then actually leads into a little bit something else we we may have neglected and this is a gut check project the gut check project is basically brought to you by KB MD health so this is Ken Brown can Brown medical doctor so KB MD health.com is where you can find a lot of the research it will be posting is a brand-new website started a week ago and from there will be able to help bridge that gap and show your methods in terms of the research the proven science what works what doesn't work and you can even give suggestions on people you would like to see him get check project from KB MD health I don't it's we talked about Halifax I think it was three years ago that I would spell effects of the speaker just to check out to see if we should be a sponsor and that's what I want by the elixir no oh yes and a looks and all is I've since learned is a company that is fantastic they been doing the right thing the entire time tossing IG industry really vetted a lot of companies and ultimately is the company that I partnered with but is really funny because what happened as I walked by the booth and a person is not friend Christine said this is three years ago hey you you know anything about the ECS and I am a medical doctor like I know absolutely nothing and she just proceeded to vomit so much information on me that I liked what I'll buy a case ship it to my office and I literally handed out hemp garage CBD to my patients for free and I just said look I know what she was saying at that time to there's so much information was coming at me so fast all I know is that just about every patient came back and said I need more of that and that's when I knew that okay I need to do a deep dive for the last three years I've been really diving deep into this doing more research this is a functional medicine type research were to find different ways to apply this but using science will have fun but I also want to talk science downdraft talk sets in fact working to get into that later today about ECS and what it is that it means to you and then I think you and I can both completely admit that regardless to manage the training or your med school and why not ECS not talked about we talked about the digestive system we talked about the skeletal system nervous system etc. that particular system which everyone has completely and it's fascinating because it's just not talk about a medical school and so when you go to medical schools do we get busy yet and we don't know that's our job will be teaching that and were looking over at one of our mentors here we got music, and I guess that means we need executive break as the first half-hour catching project holy child thank you all for joining us we will be back here at the bottom now you can fly anywhere in the world and paid discount prices on your airline tickets flight today to London Paris Madrid or anywhere else you want to go and pay a lot less Gary call the international travel department right now low-cost airlines 800 452-107-5800 452-1075 that's 800-452-1075 fast-track student loans can get your student loans out of the vault stop any wage garnishments stop collection calls and stop seizure of your tax refund give yourself a break to stop the stress and get your student loan payments down to as little as $25 a month based on what you can afford to pay 800-709-4395 800-709-4395 800-709-4395 800-709-4395 have you done it you catch a glimpse yourself in the mirror I'm I'm with those people you don't want to see naked IBM most of us but I mean you look and you're going to die I know I get to whatever you call it's horrible hey that's Dr. Townsend and Brad Staggs to tell you about a different way to shed those pounds this is brand-new technically been around for a couple years or so it was based on research from the University of California that said there is a molecule called OEA that's found naturally in your body produces it in the Mediterranean diet that when taken concentrated amounts it will actually make you feel fuller and boost your metabolism I lost about 10 pounds so far is a mere amazing Valley school company said we can take this to market to make this great product will help you it's called grid you zone our IDU zone.com our IDU zone.com Brad's work does work Brad's work for me countless other people go to read you zone.com and try today you're going to love it read you zone.com remember that our IDU zone.com all rights we are back with the second ever half hour of the gut check project I just heard in my headphones alive and read for which is the riches of I have heard of them also into Rich's own my good friend Dr. Jaeger. The medical director of that and this is super exciting because ridges own happens to actually function like a typical cannabinoid that said the science that we could get into the oh EA oh eat a fascinating it is in all of oil extract that when he gets in small bowel it gets broken down into something that functions like an Endo cannabinoid it suppresses your diet I have no stock in the company of anointing only CJ and his CEO Cecile Sasi Sasi on CJ and Sasi Excel 1 of the things that I do want to bring up on the show for everyone I want everyone have all the knowledge I want every company to succeed I want every advertiser do well basically what I'm saying is a rising tide lifts all ships it does indeed just to reset this is Dr. Ken Brown this is his first episode of the gut check project he is a board-certified guesser neurologist so we left off last half hour talking a little bit about will why were here and the whole idea schedule bit more specifics here for this half-hour so you last half-hour you mentioned that your you want to build bridges between natural and medical science and that's a really kind of the flyover term is a lot of debt to that and I've seen a lot of that debt since you have been working together so once you go ahead and and tell us a little bit about what that isn't what led you from going to med school working as a gastroenterologist all the way down to the road where you want to see what works on both sides both medically and naturally so like all things always go back to school thing signed like all things I think one of the most influential people that has affected my career is getting Leonard Woods was a physical therapist somebody that I also get even a step back further and so good work you have all these people is just so I grew up with a great friend and Junior Bryant he played and of going to Notre Dame and played football there in 49 or 49 of them played for about 12 years and 49 as well a lot of people don't know is that his eighth grade summer a water heater exploded and burned him with his mother he ended up living with me because his mom still in the hospital so he calls me up for Michigan and says the doctors go discharge me I kinda need a place to go riding and asked my parents right beside you live with me still dental my mom and dad hey Junior as you live with us so he spent some time with us and a moment happen where the doorbell rang and again I said my name is Leonard Woods I hear that you have young man has been burned I'm a physical therapist I want to help out at night like okay and then he ended up taking rehabbing Junior making him state champion shotput go to Notre Dame Fulbright football playing whatever the junior always get back to the burn burn victims and burn burn community and now were talking with him about CTE and football and all that so it's really we kept the relationship going little puncture but when you when you have a moment like that were somebody just altruistic Lee brings her doorbell Chris Acree people out on the doorbell you now but but but 30 years ago some 30 years ago I don't yet I don't date myself so yeah so anyways that he pulled up his horse and buggy and but so that that I would be physical therapist and so I ended up doing all through college I worked in a burn unit and I just I did trauma victims and things like that and then I ended up doing mentorship with Woody Leonard Woods when you really admire somebody and he pulled me aside and said dude you need to be a doctor I think that this is I think there's there's more out there for you and then that's when you go from believing okay I'm here to the guy that I really admire says I can be here sure and ever since then it's just been a passion to just break down barriers and figure out ways and hopefully due to her altruistic way and hopefully do it in the safest way possible and so on so that's I got into clinical research so after much about school did my fellowship two years into working at D had to just of health Associates Sgt. clinical research and I one of the first projects that I did was on a drug called by fax and Dr. Mark Pimentel if anybody's ever had any experience with bacterial overgrowth called SEBO well he's kind of godfather that he definitely is located on California and so when I saw the work that wouldn't do that now is one of the leading enrolling sites in the country for their first trial that ended up getting published in the New England Journal of Medicine so they spend like $30 million to put the study out there they go to him to be a speaker form I'm watching all this this is fantastic it's a novel treatment it's safe it's everything that I'm all about its new science that makes notes older at the 11th hour the FDA pulls the rug out from under him and says you know what we want more data they'd already hired salesforce they had already had people that had moved their families out of money and time so much money in time so there is the whole machine is so much bigger than people realize there's a lot of people in the farm industry that are put their whole life on the line. So it's not like this is good or bad it's that these are just different industries and you we may have a few things broken I think that possibly we allow devices to come to market maybe two quick look at a show called the bleeding man she had a bleeding edge on Netflix that'll kinda get into that and on the flipside I think that we have products the FDA is just there to show if it's safe so the 11th hour the rug was pulled and then they had to do a hold of the trial that took about four more years will in that that. That's when I was looking at it and am still in contact with all the scientists around the country and I'm like wow there is a big hole being Mr. we could probably solve the problem using mother nature okay and that was the first time that ever thought about anything like this in the actual story behind this event to return any of my other podcast my real story is I'm talking to Dr. Pimentel he is explaining that will never be able to help the bloated person with constipation is there producing methane gas by fax and doesn't affect the type of bacteria the produce is that at that time I research manager Brandi comes in my office is like why did you write method on the board such scruff the phone as crazy as it turns out it's about methane which is very time appropriate because that Congresswoman oh I forgot her name so we will have to remind about that that that young woman was talking about the greenhouse effect and how we have to get rid of cows Co. Locascio yes I just read that on-site home and we been talking methane and cattle for a long time lesson Brandy goes hey when I was a policy letter for Sen. in Iowa they were trying to mandate that farmers put certain food products in the cattle feed to prevent the methane production in the stomach I think she had inadvertently on her website to her big thing was that she said how parts were causing everything sure is really Cal burps because I just ruined it right and so that's what's happening and that was the aha moment I just went holy how it literally literally holy cow yet a bloated cow came through with all this and that's when I said can get some of that data all that animal data somebody did on leg workforce it's out there just nobody's taking the time to do it because everybody is focusing on rocks that's how we ended up developing outrun to and I believe it's tip of the iceberg I believe that we can do this with other things one of the things we have in my back pocket I have a I have a good friend that is an incredible researcher she will find any article ever any time and so somebody has any questions about hey does this work but no let's see what happens a lot of times the problem with doing natural research is that you even know what you're actually looking at right what I mean by that is there is a study the cannot 2015 where they looked at products at GNC Walgreens the major the major players and they show that almost 79% of those products did not actually show what was in the capsule what was on the label through DNA analysis right so it's 80% of the stuff that you taking might not be anything I not be anything I don't think that the people that are marketing those those that products really care they only care they got caught well it could be that it could be that they don't know that they may not know they may not know you have the best of intentions that a leader you will certainly without her until we hire our own third-party testing rack check the top middle and bottom of every single batch of natural ingredients original does that also absolutely that's why the KPMG health remember upfront till go to love might help me.com/spoony SPOONY show some love with that because that's just going to only keep growing and so when we start talking about natural research the first thing we have to do is are you looking at the ingredients are on the label lemming that is a recent study just came out pretty basic and melatonin melatonin does amazing things for you there's lots of evidence that it actually work on your end of cannabinoid system we can help with your acid reflux it helps you sleep and a recent study to show that when they analyzed melatonin it could be anywhere between .5% to 400% of what's actually in late right so when we start talking data if I come to you and I'm like you know Eric I would like you to start using reserve patrols and antiaging product to show me the data and the data is inconclusive it's all over the map that's looking the people that did the studies may not even realize they didn't spend money to do third-party because it costs so much money how they recoup now you're right on and I also think that in the natural space number one I think what you're alluding to is or may not be enough money in there to publicize the results another thing is when people are doing natural research there researching without prejudice they are doing it to find necessarily just some print a pre-determined endpoint they are just trying to say this is going to work and were going to make sure the numbers were there just doing research reporting research and sometimes it just lays uncovered because it's not heavily funded build on the search for just as you describe and it lays dormant until someone begins to put the pieces together so, describe how that had applied to you and in terms of what you wanted to do to build a bridge between natural in medical science from understanding what natural could actually do to give real results so in my practice and seeing things in my own self like I said I'm but I consider myself as the bio hacker to a fault I will do all go on like one of mycelial were my favorite pupils Ben Greenfield it's funny because he'll do anything to himself I called it when I want to show whatever we we talk research we always talk about the and of something meaning the number of patients to have an outcome and so it's the end of one the end of two whatever I called it the bent of one anything to them so I'm kind like that so I'll call I'll do a podcast the patient will tell me something like I'm on it yeah let's do this and see if it works and I evensong myself I would order different brands of the same thing and I could see different results so you know that there's different things going on so the first thing is I want to make sure that anything I recommended to the patient was third-party tested trip so they know exactly what they're getting so if I say you're going to have better sleep because this melatonin to work I know that are trying to is NSF certified so you can as Olympic athlete you can take that right are certain certifications for that that actually led to my own digestive group she had actually were about ready to launch our subscription box where health arrives to your home were to do that vetting for you which is so cool that they're cutting edge enough to do something like that so basically it's a large G.I. group that knows that their patients take supplements and they want to make certain that if they know their patients are taking supplements which are over-the-counter and they have the opportunity to take various supplements and all different kinds of brands this is a G.I. group it's taking a step forward and say okay we know you're doing this let's help give you some guidance is that, you're describing that's exactly it and this is all going on right now as we speak so amazing it's so cool this was actually present we have a unique opportunity I'm with Simon several healthcare entrepreneurial groups I think I've seen you at the meeting of Bender wanted to do so word several groups and because that were exposed to some very exciting people both in the science side and the business side trip and one of the people he came in contact with he said looked if you guys are so concerned about the health and your community take some ownership of it step up front and say I want to at least vet these things for you and in my opinion if you cover the three primary pillars of health which is gut health all health begins and ends in the gut forgot isn't healthy nothing else will be brain health what's the point of all of this when dementia and Alzheimer's is exponentially increasing must protect that and then forget about the other side of the epidemic of autism right onto the roof left brain health also share an anxiety and depression and all the other things and then ultimately sleep if I can get if I can fix it got protect the brain and get people to sleep there can have all the things they want in their life which is weight loss more endurance better mental clarity all of the above energy happiness and it comes with those three pillars no doubt yes I'm super excited that my company D had decided to do this I want to double down on this right now and say that I truly believe it will be the first large group to do natural research and just show unbiased research that knowing full well that is not to be a whole lot of financial recourse in it but were doing it because we care you want to change the landscape of the health and in our community and hopefully expand beyond our community through stations like spoony radio sure so eight nowadays you you definitely see kind of this this weird split Emerging where if you were to go back to the 80s it was if you're sick go see a doctor and you and your physician so if you're sick go see Dr. if he and you feel this way and you don't feel well go see a doctor and then ultimately that time of course all physicians for the most part want to do their best by their patients but they can they can only do it from the research and the information education they received in school why do you think that we had to shift over to natural medicine number one number two what is it that kept people from embracing some of the natural medicine and then maybe even what are some of the limitations in leaving the medical world behind and ignoring still the good parts that could be in the medical side all just for for natural because you say you want to build this bridge what is it about the good sides of both bringing them together to help people find relief that you found that this is a reason you help people build this bridge so when we look at the pharmaceutical industry will people don't realize is that the way that pharmaceutical companies can communicate with doctors has actually changed over the years and I've done that probably for the good of the whole industry trip in my in my opinion I mean when I was in medical school it was pretty wide open I will get to a look at there's a whole lot of of pharmaceutical reps would have to spend the money hey wait a minute that reminds me of a story and never do the job but yet you good drug rep at one time it's not important important thing is is that you learn lessons and you move on so my marinara care was actually he's been in multiple industries I want you to tell the story because I think it's a really cool and I think it shows where you are at the whole time sure about the hamburgers yeah so we we often were given entertainment budgets and I know that you were the beneficiary of some those entertainment budgets both as a medical student and of course as a physician because how else are you going to get someone's time to tell your message you are a a drug rep and you feel altruistic and yet this is not out there I'm not judging any shirt field or anything it's everything the business over things and industry everything what is it's really hard it be really hard to to see me and get any attention if you're not gonna bring in some food my staff is just the nature of it unfortunately when you and you have to get access because you that the physician is there to serve the patients and so how is she going and access but you have to basically enticing and make it okay for the staff to come and pay some attention to your message along with the physician so we were given a very very large budget and at the time I had mostly a rural area that serviced and I just I couldn't possibly spend all of the money that they kept allocating for for us to spend and and in yellow everything is measurable my numbers by quarter were fine and so I just got to a point where I realize I had all this entertainment money and I didn't really see the reason to just keep buying snacks and things that people wouldn't necessarily need or enjoy the office so I started going and buying just bulk numbers of hamburgers and going to Port Said the town both in Ardmore and Wichita Falls pulling up in my little company issued Jeep liberty opening up the back and and handing out hamburgers and the weird thing that happened there was one day I advised I think 47 hamburgers from the two frogs Grill in Ardmore Oklahoma and I drove to the east side Oklahoma there's a great guy up there in the town's name is Dr. for and I'd Artie been by's office earlier that day but he saw me and he saw me with a bunch of Styrofoam boxes handing it out to people in Ardmore and he stop mePsalms it will be doing Antonella handing out hamburgers that is what one over somebody who is more altruistic he liked the fact that I was taking the money and he knew that most physicians know it's a simple entertainment budget and you're doing it to gain the attention of somebody are hoping will recommend your product produce sales but when I was really doing was I just saw surplus and I thought there's no way could benefit from this better than somebody just truly hungry today so I bought a bunch hamburgers and handed them out and it turned out that through just dumb luck in turning to be a great sales pitch for me doing the right thing eventually pays on a daily basis and has one thing yeah and you know we took we talked about this that everything is still an industry it's still businesslike I said these people get their products out there and they have to get in front of doctors and when we launched our trunk heel I try to get production right away complain that sandbox right way too expensive so you we learned our lesson that Lorena let them do that but PeopleSoft make money for instance Platelets that sandbox were plain on spoony radio so go to love my tummy.com/spoony put in the code spooning SP 00 NY of an supports companies like upfront to heal so that you know we eventually can start doing some of this natural research when you are asking earlier about why you think there's this shift what you think Chris Kress are in the compressor Institute and the Cleveland clinic in Mark Hyman and all these people and Dave Asby are gaining so much traction talking about this kind of stuff and I think it's because a great example when I was a resident I was working a geriatric clinic and people would come in and every time they go see a doctor so if they're sitting there and they have no five or six doctors every doctor just given a drug they go so is it geriatricians are spent three years working in geriatric clinic I would look at their meds and go don't take that don't take that hill… When you're 95 years old and are on so many pills so many pills so I think that people get very frustrated that they go to the doctor the Department of medicine and they're not getting the results of because of the Internet and the information that is available like shows like this like shows like Brody talked about Chris Presser showing thing Bob.Rob good people are becoming important chair so it's no longer on just go do it what my doctor says that's why there is this movement dysfunctional health slide so excited about this member box that were good it would be you brought some accounting interesting earlier neat and he said that that the FDA's purpose there with that drug research is to make certain that the drugs most of our foremost aren't harmful but then there's an element where they had to show a little bit of efficacy what was the funny realization that you found it happens in the pharmaceutical or medical side for a drug to get approved for to be recognized is making a difference over placebo versus what you are able to do with a natural product before you even branded it and you realize I has something that's different it's already safe but it's actually making a difference so in my space in the gastrointestinal space when you have a disease called like irritable bowel syndrome with the bloating and change in bowel habits a lot of the drugs that are available even drugs that I like to get pulled off the market share after they found them to be unsafe like Zelnorm everything is around 9 to 10% better than placebo and the really expensive and so when we started figuring out natural ways to fix people were having better results mean the reality is we can get 4 to 5 people feeling better if you have the right symptoms in its natural cheaper it's affordable so whenever I think of anything is it available is it affordable is it affected those are the three things will be FDA's main goal is are you going to cause harm right that's what they're really being paid for are you going to cause harm not so much Arrigo determined that this is a very effective product Ricoh make sure you can hurt people and that's under drugs come around I was looking at the an article written get into that in the next hour because I think one of the things we can really talk about a lot is CBD cannabidiol the inner cannabinoid system and get into that and talk about how that inner plays with certain diets but as it turns out the pharmaceutical industry is really trying to get involved with that industry shredder figure out how to manipulate different enzymes one of the problems that we see all the time is that mother nature will do something and then the farm industry will need to have a patent and so they have to extract and manufacture a molecule and then put a drug name to it and say this is going to do this and we've seen that time and time again without question when pharmaceutical companies what I'm learning in the functional spaces mother nature since the do little bit better with right diet you take a whole client you take the whole molecule and not try and mess it up your body will figure out what to do with it work better than work but a great example a great example is that the Mediterranean diet for instance sure is filled with molecules called polyphenols follow polyphenols make vegetables colorful that make fruits colorful when you eat these polyphenols are poorly absorbed but they go to your colon where your own micro biome if you have a healthy micro biome will break down these molecules into beneficial anti-inflammatory antiaging molecules called Euro Lutherans and different things like that were learning more and more about that you cannot reproduce that with the drug right now because it's so complex were working with scientists down in South America and I there are several PhD's of come up and we go out to dinner and talk there like it is these micro biome or doing things that we can never reproduce in the lab is very deep it's really deep really deeply so and you know when you when you talk about pharmaceutical industry does tomatoes isolate that that's that's again they been doing for quite some time you hit on the fact that I had some experience in that pharmaceutical side I can still remember when they when they launched Roseann and Roseann is melatonin but it's an isolated melatonin and they told us it would have 14 times the affinity to the MT 192 receptors to induce sleep and even though they thought that little isolate was the trigger and actually underperformed it didn't do it any better then home melatonin did that's why I don't find it anymore and I believe that's why think that we can start seeing this whole shift back if we can just find a company that can bring some validity to it so that people can walk into a doctor's office and go look this study did show this it's unbiased this is what came out this is what happened we need to start doing that and if you're costing more money because with the prove that it's third-party analyze we need to make sure that we team up with companies like examine.com or consumer labs.com and make sure that everything comes to the things that are certified NSF certified and so on so yeah I don't really get a little deep here on under that aspect of that's I'm so passionate about functional medicine because there is real hope people go to their doctor and they get told no try this antidepressant try this anxiolytic take this you'll be fine take this pain medicine when young this year were making our first appearance I believe it to the IBM conference will be in San Antonio of the functional medicine conference yeah that place is filled with physicians and it grows by number every year that are just in the same position that you are and we meet more and more than every year medical met MDs DO those who have been trained in med school how to deal with disease and situations and more more they find it doesn't just exist in the pharmaceutical answers there are things beyond that their natural diet sleep whatever related that are going to help my patients feel better and then look at the opioid crisis that were doing with did you see in the news today that a police officer did a stop the woman handed him something and it appeared to be some sort of affordable fentanyl now and needing dark in the cop on a traffic stop oh because of that TOD by touching it by touching that's ridiculous I know it's crazy and I hate to interrupt the ship Patrick but did you know that dads up the fish that are coming out of the Puget Sound are contaminated with opioids I guess it's not filtered out during water treatment process so it's it's crazy nuts it's fit no fish no floundering new finfish their head up if you want to double down you have yourself some puffer fish sushi yeah you go to the tocsin or the fat know it's going to get you you can catch all your fish with a narco net pay that's the end of the first hour of the get check project things were hanging out we will check up with you here in about five minutes is five and I guess this is the only 24 hour take anywhere platforms dedicated to food and fun career spoony Townhall.com, as the Senate debates the green new deal the biggest disagreement appears to be over exactly what is in the Democratic plan and say the bill seeks to turn the country into a socialist state minority leader Chuck Schumer and says those concerns are way overblown they exaggerate they tell Miss truths but Sen. Mitch McConnell says there's only one green thing about the green new deal the huge unprecedented pile of middle-class families money the Democrats are itching itching to grab McConnell's promising ascetic boat soon on the green new deal but I knew Capitol Hill former Florida police officer facing up to life in prison after being convicted in the fatal shooting of a black motorist whose car is broken down along an Interstate 41-year-old Newman Roger shot 31-year-old Cory Jones in October 2015 an American journalist detained in and then deported from Venezuela County windowless fleet several hours late and deported back to the US executives at his Miami-based TV station and union representatives went in hundred 24-1 in foyer's most recently working as a freelance stylist for ABC affiliate local 10 years in Miami correspondence area shackling KID says it's the worst she's ever seen the Alabama Gov. talking about the massive destruction caused by the tornadoes it pummeled Lee County last weekend is truly tragic is nothing but splint was left to think size all broken up you talk about the loss of buildings and homes and livelihoods shelf this is horrendous devastation the death toll in the small town of Beauregard stands at 23 heavy losses on Wall Street the downtown 232 points more on the stories@townhall.com mold is a better way take the pain out of ordering your diabetic testing supplies with diet Thrive diatribe ships the testing supplies you need directly to you when you need them best of all with plans starting as low as eight dollars a month diatribe is probably going to cost you less than what you're paying today diatribe is so convinced that you love their service they're offering your first month of supplies free simply type the Kodak DOC and checkout diet Thrive.com that's DIA Thrive.com never forgotten apparel is more than just the premium women's and men's clothing line it's a movement to remind us to wear American-made and serve those who serve us our heroes never forgotten apparel gives 20% of their total sales to nonprofits that support homeless veterans and off-duty firefighters and 50% to individual veterans and firefighters in need nationwide checkout never forgotten apparel.com use promo code Matt and ATT and get 15% off your purchase have you done it did you catch a glimpse of yourself in the mirror I'm I'm one of those people you don't want to see naked IBM most of us but I mean you look in your gonna die I know I get to whatever you call it's horrible hey that's Doc Townsend and Brad Staggs to tell you about a different way to shed those pounds this is brand-new technically been around for a couple years or so it was based on research from the University of California that said there is a molecule called OEA that's found naturally in your body produces it in the Mediterranean diet that when taken concentrated amounts it will actually make you feel fuller and boost your metabolism I lost about 10 pounds so far is a mere amazing ballet school company said we can take this to market to make this great product that will help you it's called grid you zone our IDU zone.com are IDUs zone.com Brad's work does work for Brad's work for me countless other people go to read you zone.com and try today you're going to love it read you zone.com remember that our IDU zone.com all rights back for our number two they have not kicked us off the gut check project try design will receive the over under I'm seeing these guys exchange money over here I buy yeah I got a 14 seconds hey I just heard an ad for rigid zones like we did the last half hour and the person doing that live raid was the late Doc Thompson want to give a big shout out to him and do all of the crew here at spoony Patrick Ron Tom thank you so much for having us this is when I was in the books is been a lot of fun so far is a lot of fun and this is this is one of the essays will reset in the last hour the rising tide lifts all ships I really want to see these guys succeed there the really busted the tail to get out there something more important in a state if the people I see what you look like you know I met the frog is very handsome but I think that appreciating the TV as well you can get a Facebook and go to this many radio paging that I turn to page and it streaming live there and I going watch the video like it – it's pretty fun not to mention Nicholas on speaker and also in iHeartRadio dealership Patrick I think is good there we were just talking between the sets about how to get more views and you imagine more nudity and Shepherd has the air America was a male model so was the nudity our CEO texted me and said thanks the Shanna Fisher mention my last name so shout out check Scott because when I think of validity I think I just got there we go yeah that's yet he shows A lot in all seriousness we do want to get back a little bit on-topic in terms of what were trying to do here for our first ever got check project and that is basically laid on the format what we can expect whenever you tune in each week to get a project because this this banter course you you may see both as you will almost always see Dr. Brown it is not going to be the cornerstone we will have some great guests on we will be talking about a bunch of the great topics from everything from research with stem cells to how to exercise to the cannabis industry to polyphenols to on and on and on various topics but today were going to basically let you put a strong idea in terms of who is Dr. Kenneth Brown and why is it that he's he's doing that so we left the last half hour talking little bit about bridging the gap between natural and medical science and is removed to the next half hour let's talk a little bit about what it means to examine some other serious systems that have been somewhat ignored in the body namely the ECS the Indo cannabinoid or cannabinoid system however you Mr. Burnett set tomato tomato so what do you want to say briefly you what we were talking and your super comfortable for Mike, I'm a little more nervous than the stuff I actually a background for me as a child I started growing up so being TV and radio and stuff so stressful but is really cool that your talk about what your dad taught you because your dad was in radio was yeah and unfortunately he died two years you yesterday to have your so shut out to him as payment cycle kept him everybody but he knew my dad loved and he was those who knew him quite well and we give a yeah good little moniker that he always said which is hey guys so for those who they knew him they they know that he did it take you to the radio station your tips well reluctantly asked that I like to put my hands on the turntables and I think that he was that each identity that too much but yeah he went to the radio station several times my dad my dad was in the meat rendering process so he would take me and I could play with the kidneys of cows why am I doing this he lead you to where you were when I was holding organs introducing you to the endocrine system of the renal cyst of an animal that's what you're playing with that the when I when I was a medical school it universe Nebraska they really want an oppressed family practice doctors to go to rural communities trip and so I spent three months at a rural community where the main industry was meatpacking and injuries what happened in these doctors were overworked and I'm 1/3 year med student and stuff that would come in I look back on that I just go hold the child that's a rough one it was rough yeah I am I remember were to get back to the CSO is a cool stuff but perhaps get to know us that share where I come from now Alecto not meet there were some of me to talk about meatpacking and Ike I speak Spanish in the very first hour mention my wife's Puerto Rican my mother's Argentinian we speak were bilingual home and I was working the emergency room Lexington Nebraska a woman came in pregnant water broke and I called the doctrine: is like I want to weigh in is a true visit and he said the name is like a loose liquor a schedule talk you through is like I'll be there doorbell major she's got this down if it happens before and she did she talk me through wash your hands and just like your mask is on backward camera.your names can let you cry but she didn't have an accident but that's is the one I defaulted so we did and that's what you're saying so props your dad prompted our Thompson proxy had add props to everyone that has taught us anything sure because it's got check radio or get your project is a project and we check our egos at the door and we just learn from everybody we did that's our goal so the ECS so we've we've heard of the digestive system we heard about the nervous system the skeletal system renal lung pulmonary whatever you want to call it why is the ECS new or is it new to us this is one of those things where you walk up and props to Christine Thiel of Alexa and all and Gabriel CEO Prolixin all for grabbing me and making me listen and not by me lunch and not taking me on a trip like you know we've I've had done with farm industries sure just call me out general information you need to know this and they threat a bunch of information like vomiting it was overwhelming and now I know why it is because we have discovered a system in our bodies called the Endo cannabinoid system the throughout your entire body but the reality is if you would think it and really simplify it links the immune system to the nervous system and right there two circles coming together that's where the ECS lives so although it does all kinds of crazy things if you have anything on your brain meaning anxiety all the way from anxiety to seizures it just sort of controls it and calls it down it's a traffic cop if you have anything in nerves like diabetic neuropathy or if you've got sciatic pain pain pain inwardly writing about this on KPMG health.com sure lots because I'm so blown away that I feel like I've been gifted the ability to learn about a system that now my colleagues know about our elaborate on that just a little better because you said were going to be writing about it but I do want to draw a good distinction here and not that other people don't put in the time for research because there's a lot of people after the do it but I will say that if if Dr. Brown it can end up putting any element into a level research to have something written it's because it's actually happened everything that you've done as long as I've known you is well I've read this about it let's find out if that's true and so that's really what KB MD health is all about is basically to spread the information good or bad about how something does may or may not work and so is is that something that you found somewhat inspiring to be able to dig in deep whenever you first started working with the CBD you if our member correctly like arms can see this works and find out what happens yeah so the first so what ended up happening is three years ago was appellee or fax which is conference I like in Austin and I was walked by the elixir tollbooth I got grabbed and I was being support information didn't know anything about it and I love the passion sure someone one thing that I will will always be drawn to his passion and so if you're passionate about anything those things I don't know about and working to bring those experts here yeah order bring essential oil exports and because I know about it and I want to learn and it says Snyder right is a essential oil exports just published a book on that were to bring probably her into talk about it because we want to sit there and make sure they were not leaving any stone unturned but there's only so much time in t

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#085 - IF For Mood And Depression, “Melting" From IF, Not Fasting Benefits, IBSD When Breaking The Fast, Atrantil Timing, And More!

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Play Episode Listen Later Dec 3, 2018 49:09 Transcription Available

Check out IFPodcast.com/Episode85 for full shownotes and references, and IFPodcast.com/StuffWeLike for all the stuff we like! Get Melanie's Book What When Wine: Lose Weight and Feel Great with Paleo-Style Meals, Intermittent Fasting, and Wine, on Amazon and Barnes & Noble! Get Gin's Books' Feast Without Fear: Food and the Delay, Don't Deny Lifestyle Today's episode of The Intermittent Fasting Podcast is brought to you by Prep Dish and Bonafide Provisions Bone Broth! They're two fantastic companies, and we've got special deals for listeners for both!! Prep Dish is an awesome meal planning service which sends you weekly grocery and recipe lists, so you can do all your meal preparation at once, and be good to go for the week! It's perfect for the IF lifestyle! And better yet, the meals are all gluten free or Paleo, which is fantastic if you're already doing so, but also a wonderful way to "try out" gluten free or Paleo with delicious meals, and no feelings of restriction!! We can't recommend them enough! Free Subscription! Get a FREE 2 WEEK TRIAL at Prepdish.com/ifpodcast! Bonafide makes wonderful organic bone broths and bone broth soups, slow simmered for 18 hours, and completely free of preservatives! Bone broths are wonderful, nourishing foods and a fantastic way to open your window! Bonafide broths are available online and in stores near you! Go to BonafideProvisions.com for more information, and use the code IFBroth for 20% OFF!! SHOW NOTES 09:45 - PREP DISH Free Subscription! Get a free 2 week trial At Prepdish.com/ifpodcast! You'll get weekly gluten-free and Paleo grocery and recipe lists!! 13:30 - BONAFIDE BONE BROTH: Go To BonafideProvisions.com And Use The Code IFBroth For 20% Off!! 15:50 - Listener Feedback: Michelle - Everyone Should Not Be Fasting At Certain Times 25:20 - Listener Feedback: Libby - Can You Take Atrantil During The Fast? Tips For Preventing IBSD After Fasting? 34:45 - Listener Feedback: Sabine - Can IF Help Depression Due To Keto Effect? 48:30 - Listener Feedback: Elena - Does IF Make You Melt? Can It Help Depression? For information regarding your data privacy, visit acast.com/privacy

19 / How To Beat Intestinal Bloating w/ Dr. Ken Brown

Muscle Medicine

Play Episode Listen Later Nov 8, 2018 53:16

A lot of my patients are working hard on their functional movement as they try to get out of pain through rehab. Sometimes I notice that part of the issue is caused by bloating. Of course, they’re not going to get better until that’s corrected so they can stabilize their core. That’s where today’s guest comes in. Dr. Ken Brown has been studying and researching the causes of bloating and its solutions and is here to tell us what he knows. Dr. Brown is a gastroenterologist in Dallas. While doing clinical research for big pharma, Dr. Brown realized that there was a huge connection between the methane in our diet and a whole load of health problems. This led him to develop the supplement Atrantil to address the causes of this problem. Dr. Brown continues to be passionate about research into functional medicine and bridging the gap between traditional medicine and natural solutions. Bloating can have so many causes and lead to near countless ramifications. Dr. Brown and I talk about how you can identify the issue, understand its causes, and treat it in an effective way. By being on the cutting edge of research, Dr. Brown has a wealth of knowledge on this complex and overlooked subject. Have you noticed issues related to bloating affecting your health? Leave a comment! In this episode: Some of the common causes of bloating Your gut biome and its role in creating bloat-causing gases like methane The causes and consequences of leaky-gut and what you can do to avoid it Understanding the polyphenol content of what you eat and how it has many different health benefits Steps you can take to get rid of bloating Quotes: “You don't need to give someone antidepressants because they’re bloated. You need to fix the root cause.” [5:31] “The multibiome interacts, and if you eat poorly and keep abusing your body, you’re going set yourself up for a situation where all you’re doing is feeding this little ecosystem in your body.” [15:46] “Wouldn’t it be fantastic to change lifestyle and make a huge difference in people’s lives as opposed to always throwing a drug out?” [37:19] Links: Find Dr. Ken online Atranil Love My Tummy Digestive Health Associates of Texas Check out the full show notes for this episode here Urban Wellness Clinic Follow Emily & Urban Wellness on Facebook | Twitter | Instagram | YouTube

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#080 - Tips For Starting IF, Fasting Without Coffee, Fasting In Chunks, Kale, Saunas, The Diuretic Effect, Weight Tracking Apps, Facebook Groups, Rodent Study Implications & More!

Play Episode Listen Later Oct 29, 2018 61:10 Transcription Available

Check out IFPodcast.com/Episode80 for full shownotes and references, and IFPodcast.com/StuffWeLike for all the stuff we like! Today's episode is sponsored by Atrantil! On Episode 79, we discussed the amazing Atrantil with its founder Dr. Ken Brown. Atrantil can help you beat IBS and SIBO! Atrantil contains natural herb compounds which work syngeristically to control bacteria in the small intestine, while also providing antioxidant and other GI benefits. You can use Atrantil to reduce (or even eliminate!) gas, bloating, constipation, and diarrhea, and also to support digestive health in general! Be sure and give the product a full 30 days to evaluate it's effectiveness, as it can take that long for some people to get your gut bacteria back in line, but it's so worth it!! And it's got a 100% money back guarantee! Use the link lovemytummy.com/ifp with the code IFP, to get 10% off your purchase! Get Melanie's Book What When Wine: Lose Weight and Feel Great with Paleo-Style Meals, Intermittent Fasting, and Wine, on Amazon and Barnes & Noble! Get Gin's Books' Feast Without Fear: Food and the Delay, Don't Deny Lifestyle SHOW NOTES 9:30 - Listener Q&A: Michelle - Tips For Starting IF? How Long To See Results? 20:40 - Listener Q&A: Anne - Too Much Raw Kale? 26:55 - Listener Q&A: Vaun - Benefits Of Using The Sauna While Fasting? If You Order A Joovv With The Link Joovv.Shop/IFPodcast And Forward Your Proof Of Purchase To Melanie@IFpodcast.com, We'll Send You A Free Gift! 30:00 - Listener Q&A: Vaun - App For Weight Averages? 34:05 - ATRANTIL: This amazing plant-based supplement can stop your GI distress and restore your gut microbiome!! Use the link lovemytummy.com/ifp with the code IFP, to get 10% off your purchase! 36:15 - Listener Q&A: Vaun - Soapwalla Natural Deodorant Cream Recommendation 36:30 - Listener Q&A: Vaun - The Difference In Gin's Facebook Groups? 39:20 - Listener Q&A: Vaun - Melanie's Facebook Group? 41:20 - Listener Q&A: Vaun - Does IF Have A Diuretic Effect? 43:15 - Listener Q&A: Nai - How To Fast Without Coffee? 50:05 - Listener Q&A: Wendy - Can You Fast Two Different Times Instead Of One Long One? 54:25 - How Fasting Affects Rodent's Body Weight Different Than Humans (And What This Means?!) For information regarding your data privacy, visit acast.com/privacy

#079 - Dr. Ken Brown & Atrantril: Fixing GI Issues Fast, IF & The Gut Microbiome, Plant Polyphenols, Fasting Mimetics, Stress, Seratonin & The Gut, IF In A Pill, And More!

healing eating effects symptoms gut health microbiome parasites leaky kiran leaky gut gut microbiome histamine microbiologist dysbiosis kiran krishnan atrantil guthealing

Play Episode Listen Later Oct 22, 2018 72:49 Transcription Available

Check out IFPodcast.com/Episode79 for full shownotes and references, and IFPodcast.com/StuffWeLike for all the stuff we like! Today we have a super special episode all about intermittent fasting, gut health, the gut microbiome, polyphenols, fasting mimetics, addressing GI distress, and more!! It's with Dr. Ken Brown, developer of the plant-based supplement Atrantil, which can reduce and even eliminate gas, bloating, and GI distress through the powerful polyphenolic power of plants! And just for our listeners, use the link lovemytummy.com/ifp with the code IFP, to get 10% off your purchase of Atrantil! Get Melanie's Book What When Wine: Lose Weight and Feel Great with Paleo-Style Meals, Intermittent Fasting, and Wine, on Amazon and Barnes & Noble! Get Gin's Books' Feast Without Fear: Food and the Delay, Don't Deny Lifestyle Today's episode of The Intermittent Fasting Podcast is sponsored by Prep Dish! Prep Dish is an awesome meal planning service which sends you weekly grocery and recipe lists, so you can do all your meal preparation at once, and be good to go for the week! It's perfect for the IF lifestyle! And better yet, the meals are all gluten free or Paleo, which is fantastic if you're already doing so, but also a wonderful way to "try out" gluten free or Paleo with delicious meals, and no feelings of restriction!! We can't recommend them enough! SHOW NOTES 2:15 - Dr. Brown's Background 7:00 - IF In A Pill? 7:25 - Why Do We Have SO Many GI Issues Today? GI Issues In Europe Vs. The US (Pesticides And Gluten Oh My!) 10:30 - IBS, Leaky Gut, Behavioral Changes, And Food 12:40 - The Role Of the Gut Microbiome 14:30 - How Fast Does The Gut Microbiome Change? (24 hours!) 19:05 - Stress, Seratonin, And The Gut Mind Connection 22:10 - IBS Motility Antibodies 22:30 - Fasting To Stop Gut Dysbiosis 26:30 - Falling Off The Wagon (It'll Be Ok!) 27:40 - Making A Change In One Day 29:30 - What Does The Clinical Literature Say About IF? 29:45 - Prep Dish: Free Subscription! Get a free 2 week trial at Prepdish.com/ifpodcast! You'll get weekly gluten-free and Paleo grocery and recipe lists!! 36:30 - Fasting Mimetics And Polyphenols During The Fast 38:40 - How Does Dr. Brown Eat? 39:00 - Addressing Food Phobia 41:50 - Melanie's Experience With Atrantil 41:40 - Homemade Atrantil? 47:50 - How Does Atrantil Work? 51:30 - Should You Take Atrantil If You Don't Have GI Distress? (Yes! Anti-aging, Anti-Inflammatory, Supports GI Health!) 53:00 - "Postbiotics" From Food 53:30 - Atrantil + IF 55:00 - The Importance Of Brain & Gut Health 56:20 - How To Take Atrantil With IF 56:20 - IF In A Pill? (Fasting Mimetics!) 59:20 - Atrantil For Athletes - Atrantil Is The NSF Certified Supplement For Athletes For GI Issues! 1:00:05 - The Necessity Of Commercialization For Legitimacy And Access? 59:20 - Atrantil For Athletes - Atrantil Is The NSF Certified Supplement For Athletes For GI Issues! 1:03:40 - French Town's Longevity Thanks To Wine? 1:04:45 - Getting Worse Before You Get Better? (Hacks For DieOff) 1:07:45 - SPECIAL OFFER: Use the link lovemytummy.com/ifp with the code IFP, to get 10% off your purchase of Atrantil! For information regarding your data privacy, visit...

Healing Leaky Gut and Dysbiosis with Kiran Krishnan

Women's Wellness Radio

Play Episode Listen Later Aug 7, 2018

Kiran Krishnan is a Microbiologist with over 20 years experience in the probiotics industry. In this webinar we did in May, Kiran talks about leaky gut, the microbiome, gluten, the immune system & supplements for a leaky gut. Here's what you'll hear: Min 03:20 Introduction to WWC Min 04:05 Kiran Krishnan & his work Min 08:35 Leaky gut progression Min 13:13 Effects of a leaky gut Min 17:15 Effects of stress on the gut Min 20:40 Symptoms of a leaky gut Min 23:30 Is leaky gut genetic? Min 27:15 Gluten & Megaspore Min 33:25 Eating right Min 35:50 Megaspore Min 43:20 Getting the right probiotic Min 48:25 GI Restore supplement Min 50:25 Taking probiotics for bloating Min 54:30 GI Assist supplement & gut restoration kit Min 1:01:00 Parasites & leaky gut Min 1:04:35 Candida, immune deficiency & breastfeeding while on probiotics Min 1:11:00 Histamine Resources: Megaspore Gut Restoration kit Gut Infection kit GI Restore powder GI Assist Atrantil Healing Gut & Oral Infections With Herbs with Rachel Fresco Why Chronic Bloating Happens with Eric Rieger High Energy Morning Detox Guide No time to detox? If you are willing to put in just 5 minutes a day, you’ll see a shift in just 5 days! Grab our High Energy Morning Guide and get some spring back in your step, naturally. Learn more here...

Why Chronic Bloating Happens with Dr. Eric Rieger

Women's Wellness Radio

Play Episode Listen Later Jul 31, 2018 39:42

Dr Eric Rieger is an anesthetist and registered nurse. He is our guest this week where we talk about bloating, SIBO, IBS, gut bacteria, causes of chronic bloating, and polyphenols. Here's what you'll hear: Min 02:55 Causes of SIBO Min 05:55 Dr. Rieger's health history Min 08:45 Archaea bacteria in the small bowel Min 11:20 Other bacteria found in the bowel Min 13:50 Chronic bloating & foods that feed bloating Min 20:15 Resetting & intermittent fasting Min 23:10 Foods that increase bloating (FODMAP foods) Min 29:30 Polyphenols Min 34:50 Using Atrantil To learn more about Dr. Eric Rieger & Atrantil, visit this website and follow them on social media: Facebook Twitter Instagram Resources: Atrantil Megaspore Schedule a Free consultation SIBO Causes and Treatments with Dr. Ken Brown Most Bloating is Caused by This... Functional Health Solutions Program To learn more about our private Functional Health Solutions program, please fill out the brief form here. After filling it out, you'll get a short series of emails to teach you about how functional health coaching works, and if it's a fit for you and your case. As thank you, we provide a discount code at the end of the series for learning about us!

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014_Bloating_How to Determine the Root Cause and Alleviate It Once and For All

Detoxing with Dani

Play Episode Listen Later Jul 27, 2018 30:03

Today's episode hits close to home, because bloat has been something I've had to deal with for quite some time now. Today I dive into how my and mr. bloat parted ways and talk about different supplements and strategies you can implement to help you determine what could be causing your bloat. So come along and let's dive on in! Things Mentioned in this episode: Digest Gold: https://amzn.to/2K03q0D Digest Gold with ATP: https://amzn.to/2OmvQVV Critical Digest on DWD: https://detoxing-with-dani.myshopify.com/ Atrantil: https://amzn.to/2LEyxUx Thrive Market Link: http://www.anrdoezrs.net/click-8641210-13259173 Vital Proteins: https://amzn.to/2On7Yl0 Vital Proteins Beauty Greens: https://amzn.to/2JYzz8J The PinnerTest - Food intolerance test that analyzes over 200 different foods and your intolerance level. Contact Dani to Order 30 Minute Consultation with Dani - Schedule Here Please Subscribe & Leave a Review :) (asking nicely) Want to get notified when a new episode is released and get the inside scoop on how to have gut health, glowing skin and a gorgeous YOU?? Click here to subscribe to the podcast on: iTunes Stitcher Google Play It would mean so much if you would leave a rating and review. I would love to know how I can make the podcast better and bring you the topics, tips and tricks you all want to hear about. Plus leaving a review helps get this information in front of so many more people who need to hear it. Thank you so much for listening and taking the time out of your busy schedules, I hope this has been helpful! xoxo Dani This podcast is not meant to diagnose, treat, cure or prevent any diseases.

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How Embarrassing Gas, Bloating & Constipation Happens (& How To Get Rid Of It Forever)

Ben Greenfield Life

Play Episode Listen Later Jul 21, 2018 69:46

For the millions, including me, that have had to deal with bloating and abdominal discomfort alone or accompanied by constipation, diarrhea or both, life can get pretty miserable. New research shows that the problems start with methane producing bacteria. Left untreated, these out-of-place bacteria feed off the foods you eat and create methane gas that leaves you bloated and uncomfortable. Dr. Ken Brown, today's guest, is an expert at how to permanently fix this issue. He received his medical degree from the University of Nebraska Medical School, and completed his fellowship in gastroenterology in San Antonio, Texas. He is a board certified gastroenterologist and has been in practice for over 15 years with a clinical focus on inflammatory bowel disease and irritable bowel syndrome. Dr. Brown declares that his mission is to bridge the gap between medical and natural science. For over a decade he has been conducting clinical research for various pharmacologic companies. Dr. Brown recognized an unmet need for something natural that could help his IBS patients find real relief. After developing the only all-natural, clinically proven answer for IBS and bloating for over 6 years, ATRANTIL (ahh-tron-teel) launched in the summer of 2015. Dr. Brown developed Atrantil to help those suffering from the symptoms of IBS which we now know are caused by bacterial overgrowth. During our discussion, you'll discover: -Why bloating occurs in the first place...10:00 -The very best test to determine the source of your bloating...18:00 -The mechanism by which polyphenol would get rid of bloating, and the fascinating action of "postbiotics"...24:00 -The South American herb "Quebracho", and how it can disrupt hydrogen production and kill archaebacteria in the gut...42:00 -How horse chestnut and peppermint work together to get rid of bloating and gas, and also to heal the gut...47:30 -Whether the three ingredients in Atrantil have been studied for efficacy in the gut...52:00 -The best way for people to get Atrantil, how long to take it, and after every meal...1:03:45 -And much more! Episode Sponsors: - Get 3 cups for FREE using promo code "ben". - and . For increased vitality in your sexual health. Get 30% off your first treatment using my links! - Anti-Aging serum. -. The leading meal delivery service in the U.S. Use my link and get $30 off your first order! Resources from this episode: - - enter code “BEN” at checkout for 15% off of your purchase -Viome microbiome test - -CBD Oil -My podcast on "Restore" with Dr. Zach Bush Do you have questions, thoughts or feedback for Dr. Brown or me? Leave your comments at http://bengreenfieldfitness.com/gas and one of us will reply!

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Episode 35: SPONSORED: Dr. Kenneth Brown / Atrantil

New Frontiers in Functional Medicine

Play Episode Listen Later Feb 13, 2018 52:01

Small-intestinal bacterial overgrowth, or SIBO, is notoriously hard to treat. Patients often experience persistent bloating—and even when they find relief, symptoms can return months later, seemingly out of the blue. After struggling to help patients feel better using the tools of conventional gastroenterology, Dr. Ken Brown began to research compounds that could effectively treat SIBO-related bloating. The result of his work is Atrantil, the only all-natural formulation for treating SIBO-related bloating. In this podcast, Dr. Fitzgerald talks to Dr. Brown about dosing and treating patients with Atrantil, when to run further tests, and what other treatments can be used in conjunction with Atrantil to get the best results.

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Demonstrating expertise to connect with your clients and launch a revolutionary product with Kenneth Brown, MD

Entrepreneurs on Fire

Play Episode Listen Later Nov 6, 2017 27:23

Kenneth is a board certified gastroenterologist with a research & clinical focus on inflammatory bowel diseases and irritable bowel syndrome. He is the creator of Atrantil, the proven natural solution for bloating, IBS, and leaky-gut. Top 3 Value Bombs: 1. Your overall health starts and ends with your gut. 2. Be calm, don’t just react to situations; show people you’re in control. 3. Your success means nothing if you’re not healthy. Kenneth’s website - LoveMyTummy.com Sponsors: ZipRecruiter: Unlike other hiring sites, ZipRecruiter doesn’t depend on the right candidates finding you; it finds them. Post your job on ZipRecruiter for FREE – that’s right, FREE! Just visit ZipRecruiter.com/fire. Davinci: Davinci meeting rooms start at just $10 an hour! No wonder entrepreneurs, startups, and Fortune 500 companies use them. Book your space now at DavinciMeeting.com/fire and the first hour is on them!

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1332: Low-Carb Cruise – Dr. Lucia Aronica

Play Episode Listen Later Nov 1, 2017 36:29

Research Associate and Instructor at Stanford University Dr. Lucia Aronica is our special 2017 Low-Carb Cruise guest speaker featured in Episode 1331 of “The Livin’ La Vida Low-Carb Show.” Have you heard about the annual Low-Carb Cruise that our host Jimmy Moore helps organize each year as the preeminent event for the low-carb community? They just completed their tenth one in 2017 with lots of incredible guest speakers who are the leading voices for carbohydrate restriction and ketogenic diets, including people like Dave Feldman, Dr. Eric Westman, Dr. Lucia Aronica, Dr. Steve Phinney, Dr. Adam Nally, Tom and Chareva Naughton, Jackie Eberstein, Dr. Ann Childers, and many more! Today’s featured lecture is from a Research Associate and Instructor at Stanford University named Dr. Lucia Aronica from Stanford Medicine who will be sharing her lecture “Towards A Personalized Low-Carb Plan: Genetic And Epigenetic Markers Of Carbohydrate Tolerance”. JOIN US ON THE LOW-CARB CRUISE MAY 19-26, 2017 If these lectures whet your appetite to be a part of the festivities on the big, historic celebration on the 11th Annual Low-Carb Cruise coming up May 20-27, 2018, then it would be awesome to have you join in on the fun in the sun with all of your low-carb, ketogenic, and Paleo friends. SIGN UP HERE to reserve your seat to meet next year’s guest speakers, including Dr. Ted Naiman, Dr. Andreas Eenfeldt, Dr. Ann Childers, Dr. Ken Berry, Dr. Jonny Bowden, Dr. Jacob Wilson/Ryan Lowery, Dr. Eric Westman, Michel Lundell, Jimmy Moore, Tom Naughton, Darryl Edwards, Daniele Della Valle, Meg Doll, Shawn Mynar, Maria Emmerich, Melanie Miller, Christine Moore, Martina Johansson, Dave Feldman, Mike & Deanna Mutzel, Jessica Tye, and more. This is one event you do not want to miss if you are a fan of livin’ la vida low-carb! Sign up now and we’ll see you there next May. This is already going to be our biggest Low-Carb Cruise ever! ORGANIC BRANDS YOU LOVE FOR LESS THRIVEMARKET.COM/KETO FOR 25% OFF NOTICE OF DISCLOSURE: Paid sponsorship Join The Keto Clarity Club For $1 Blood Ketone Test Strips! NATURAL BLOATING RELIEF GO TO LOVEMYTUMMY.COM USE COUPON CODE “JIMMY” FOR 15% OFF GET A $39 BOTTLE OF OLIVE OIL FOR JUST A BUCK GET YOUR $39 BOTTLE FOR JUST $1 NOTICE OF DISCLOSURE: Paid sponsorship DELIVERED TO YOUR DOOR – WITH FREE SHIPPING Use coupon code LLVLC for $200 OFF NOTICE OF DISCLOSURE: Paid sponsorship Links discussed in episode 1332: – SUPPORT OUR SPONSOR: Organic brands you love for less at thrivemarket.com/keto – SUPPORT OUR SPONSOR: The world’s freshest and most flavorful artisanal olive oils. Get your $39 bottle for just $1 – SUPPORT OUR SPONSOR: Love your tummy with Atrantil. (Get 15% off with the coupon code “JIMMY”) – SUPPORT OUR SPONSOR: Join The Keto Clarity Club For $1 Blood Ketone Test Strips! BestKetoneTest.com –

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1328: LLVLC Classic – Dr. Richard Feinman Works Tirelessly For Low-Carb Research Acceptance

Play Episode Listen Later Oct 24, 2017 102:16

Biochemistry professor, researcher, and author Dr. Richard Feinman Is our guest in episode 1328 of “The Livin’ La Vida Low-Carb Show". The low-carb, high-fat message is a force to be reckoned with around the world. In countries like Sweden, South Africa, New Zealand, Australia and more, carbohydrate restriction has become the basis of a societal paradigm shift that has been going on in the research world for more than a decade. It’s as if we’re now seeing a second low-carbohydrate revolution underway as a biochemistry professor from SUNY Downstate in Brooklyn, New York named Dr. Richard Feinman puts it. He’s laid the case for this bold proclamation in his book The World Turned Upside Down: The Second Low-Carbohydrate Revolution. In this special LLVLC Classic edition, we bring you an interview that Jimmy conducted with Dr. Feinman, as well as a special episode of Ask The Low-Carb Experts. Listen in as Jimmy and Dr. Feinman exchange ideas about how to unravel the years of flawed science that have kept the low-fat, high-carb diet afloat, how writing about nutrition involves not just science but politics too, how the field of nutrition has very low standards for evidence, the gold standard for anything you’re trying to prove is the one that answers the question, the problem with confounding factors in diet research, when the first low-carb revolution happened in the early 2000’s, results of the Gary Foster low-carb trial and why the methodology wasn’t good, how Dr. Christopher Gardner’s low-carb studycompared, whether we will ever see a genuine ketogenic diet used in research studies, why the burden of proof is on the low-fat diet to provide the evidence, why there’s no controversy about low-carb diets in the science, how not all revolutions necessarily turn out well, why George Washington is on the front cover of his book, how to insure the second low-carb revolution is a success, why he believes the government have to be a part of the solution (although they’re inept at giving advice), his American football analogy of the quarterback with insulin in metabolism, what’s happening with the respected researchers at Harvard Medical, how the red meat studies are incredibly misguided, the “Bill Gates walking into a bar” confounding statistical variation, the “seventh egg” story about the absurdity of health conclusions from nutritional choices, showing benefit for one year does not mean you’ll fall apart in two years, and how the Journal of N=1 would be an incredible medical journal. A fascinating conversation you WON’T want to miss! ORGANIC BRANDS YOU LOVE FOR LESS THRIVEMARKET.COM/KETO FOR 25% OFF NOTICE OF DISCLOSURE: Paid sponsorship NATURAL BLOATING RELIEF GO TO LOVEMYTUMMY.COM USE COUPON CODE “JIMMY” FOR 15% OFF GET A $39 BOTTLE OF OLIVE OIL FOR JUST A BUCK GET YOUR $39 BOTTLE FOR JUST $1 NOTICE OF DISCLOSURE: Paid sponsorship DELIVERED TO YOUR DOOR – WITH FREE SHIPPING Use coupon code LLVLC for $200 OFF NOTICE OF DISCLOSURE: Paid sponsorship Join The Keto Clarity Club For $1 Blood Ketone Test Strips! Links discussed in episode 1328: – SUPPORT OUR SPONSOR: Organic brands you love for less at thrivemarket.com/keto – SUPPORT OUR SPONSOR: The world’s freshest and most flavorful artisanal olive oils. Get your $39 bottle for just $1 – SUPPORT OUR SPONSOR: Love your tummy with Atrantil. (Get 15% off with the coupon code “JIMMY”) – SUPPORT OUR SPONSOR: Join The Keto Clarity Club For $1 Blood Ketone Test Strips! BestKetoneTest.com – Dr. Richard Feinman bio – “Richard Feinmain The Other” blog – AMAZON: The World Turned Upside Down: The Second Low-Carbohydrate Revolution

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1324: Dr. Ken Berry Answers Whether Type 2 Diabetes Is A Curable Disease

Play Episode Listen Later Oct 16, 2017 42:38

Camden, TN physician and author Dr. Ken Berry Is our guest in episode 1324 of "The Livin' La Vida Low-Carb Show". Ken D Berry, M.D., has been practicing Family Medicine in rural Tennessee for over a decade. He is board certified in Family Medicine, and was recently awarded the degree of Fellow by the American Academy of Family Physicians. Having seen over 20,000 patients over his career of all ages, he is uniquely qualified to advise on both acute and chronic diseases. More and more, Dr. Berry has focused of chronic disease caused by the Standard American Diet and Lifestyle, and has made it his mission to turn the tide on the epidemic of Type 2 Diabetes, chronic inflammation and dementia. Listen in today as Jimmy talks with Dr. Berry about his book, Lies My Doctor Told Me, where he exposes lies told by doctors to patients, often in a well-meaning way, which sabotage the patient's health, Curing Type 2 Diabetes, how the Keto/Paleo Diet Lifestyle changed his life, the eat less/exercise more dogma, whole grains, why there are fat doctors, the Lipid Theory controversy, chronic overuse of PPI's (Nexium,Prevacid), Vitamin D, and much more. ORGANIC BRANDS YOU LOVE FOR LESS THRIVEMARKET.COM/KETO FOR 25% OFF NOTICE OF DISCLOSURE: Paid sponsorship GET A $39 BOTTLE OF OLIVE OIL FOR JUST A BUCK GET YOUR $39 BOTTLE FOR JUST $1 NOTICE OF DISCLOSURE: Paid sponsorship DELIVERED TO YOUR DOOR – WITH FREE SHIPPING Use coupon code LLVLC for $200 OFF NOTICE OF DISCLOSURE: Paid sponsorship Join The Keto Clarity Club For $1 Blood Ketone Test Strips! NATURAL BLOATING RELIEF GO TO LOVEMYTUMMY.COM USE COUPON CODE “JIMMY” FOR 15% OFF Links discussed in episode 1324: – SUPPORT OUR SPONSOR: Organic brands you love for less at thrivemarket.com/keto – SUPPORT OUR SPONSOR: The world’s freshest and most flavorful artisanal olive oils. Get your $39 bottle for just $1 – SUPPORT OUR SPONSOR: Love your tummy with Atrantil. (Get 15% off with the coupon code “JIMMY”) – SUPPORT OUR SPONSOR: Join The Keto Clarity Club For $1 Blood Ketone Test Strips! BestKetoneTest.com Dr. Berry on Youtube Dr. Berry on Facebook Sign up to receive a free chapter of Lies My Doctor Told Me

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1323: LLVLC Classic – Christine Cronau Putting Healthy Saturated Fat On The Map Again In Australia

functional sibo gastro ken brown kenneth brown atrantil

Play Episode Listen Later Oct 11, 2017 93:18

Australian low-carb, high-fat nutritionist and author Christine Cronau is our guest today in Episode 1323 of “The Livin’ La Vida Low-Carb Show.” In today's LLVLC Classic Episode, we have a double show with Christine Cronau. As bad as the obesity epidemic is in the United States, it’s even worse in the country of Australia. That’s why it’s great to have people who are enthusiastic about high-fat, low-carb living sharing the message so passionately there like Christine Cronau. While others like former podcast guest David Gillespie have published books on the importance of avoiding sugar, Christine is the first author extolling the virtues of consuming dietary fat with the release of her new book The Fat Revolution: Why Butter And Real Fats Actually Make Us Slim. She shares in that book why reducing dietary fat actually makes us fat, sick and even depressed. Plus, she describes why the vilification of fat is the biggest public health scam of the 21st century by presenting the facts about how dietary fats are an essential part of a healthy lifestyle. If you want to know what REALLY makes you fat and get heart disease, Christine drops some truth bombs pointing the finger of blame at the REAL culprit–carbohydrates! Listen in to hear Jimmy and Christine talk about the critical work she is doing in her home nation to bring about the changes necessary to improve the weight and health of people there and around the world, as well as her fantastic lecture discussing her journey to Fat Revolutionary. ORGANIC BRANDS YOU LOVE FOR LESS THRIVEMARKET.COM/KETO FOR 25% OFF NOTICE OF DISCLOSURE: Paid sponsorship DELIVERED TO YOUR DOOR – WITH FREE SHIPPING Use coupon code LLVLC for $200 OFF NOTICE OF DISCLOSURE: Paid sponsorship Join The Keto Clarity Club For $1 Blood Ketone Test Strips! NATURAL BLOATING RELIEF GO TO LOVEMYTUMMY.COM USE COUPON CODE “JIMMY” FOR 15% OFF NOTICE OF DISCLOSURE: Paid sponsorship GET A $39 BOTTLE OF OLIVE OIL FOR JUST A BUCK GET YOUR $39 BOTTLE FOR JUST $1 NOTICE OF DISCLOSURE: Paid sponsorship LINKS MENTIONED IN EPISODE 1323 – SUPPORT OUR SPONSOR: Organic brands you love for less at thrivemarket.com/keto – SUPPORT OUR SPONSOR: The world’s freshest and most flavorful artisanal olive oils. Get your $39 bottle for just $1 – SUPPORT OUR SPONSOR: Love your tummy with Atrantil. (Get 15% off with the coupon code “JIMMY”) – SUPPORT OUR SPONSOR: Join The Keto Clarity Club For $1 Blood Ketone Test Strips! BestKetoneTest.com – Christine Cronau official website – Get The Fat Revolution and The Fat Revolution Cookbook

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Dr. Ken Brown, MD: Gastro Doc Going Functional

The Evan Brand Show

Play Episode Listen Later Oct 6, 2017

Kenneth Brown, M.D. is aBoard-Certified Gastroenterologist who has been in the conventional gastroenterology trenches for quite some time. Now, he is incorporating more functional medicine strategies and solutions into his practice, especially with his formulation of Atrantil, an herbal SIBO formulation. They are now sponsoring the podcast, so that means you can get this formula for 10% off by using the coupon code evanat checkout: http://lovemytummy.com/evan

1319: LLVLC Classic – Ivor Cummins Brings An Engineering Mind To The Cholesterol Debate

Play Episode Listen Later Oct 3, 2017 38:13

Chemical engineer Ivor Cummins is our interview guest today in Episode 1319 of “The Livin’ La Vida Low-Carb Show.” Irish chemical engineer Ivor Cummins from “The Fat Emperor” blog began having some issues with his health when a few blood tests came back as less than optimal. When Ivor put on his engineering cap to apply that methodical approach to solving his personal health problems, he researched and examined all the evidence involved in raising inflammation and cholesterol levels and what he discovered was astonishing to him. He read over 200 studies and came to the conclusion that what we have been doing to treat things like high cholesterol and metabolic syndrome have been wrong–DEAD WRONG! THE CHOLESTEROL CONUNDRUM AND ROOT CAUSE SOLUTION http://youtu.be/fuj6nxCDBZ0 SUGAR AS A PRIMARY ROOT CAUSE OF METABOLIC SYNDROME http://youtu.be/xrsHqIKtXNw Listen in to hear Jimmy and Ivor talk about how he’s always thought in a “very technical” manner, the high iron, GGT, and cholesterol levels that caught the attention of his doctors, how he started digging through the research on ferritin and GTT which he traced back to carbohydrate intake, how he got deep into looking into several hundred studies on cholesterol that intrigued him, why he started doing seminars and creating videos to help educate people about the low-carb answer to most of today’s chronic health issues, why he used to think the food quality issue wasn’t a big deal, the mass industrialization of food hasn’t occurred in Ireland yet, why his videos are very long and extremely detailed, how Dr. Robert Lustig’s 90-minute “Sugar: The Bigger Truth” video has nearly 5 million views, the response and feedback he’s received from his videos, how his health has improved and changed since going low-carb ketogenic, how he can “sense” being in ketosis, whether he will start testing ketones for a future lecture/video, predictions about when the low-carb message will be fully embraced, how Dr. Atkins was ahead of the nutritional curve decades ago, why keeping your mind open about nutritional science is critical to progressing, and the topics he has on his radar screen (including insulin) next. Nutrient Rich Vegetables In An Easy To Drink Powder "JIMMY" at checkout to get 20% off your first order! Join The Keto Clarity Club For $1 Blood Ketone Test Strips! NATURAL BLOATING RELIEF GO TO LOVEMYTUMMY.COM USE COUPON CODE “JIMMY” FOR 15% OFF NOTICE OF DISCLOSURE: Paid sponsorship GET A $39 BOTTLE OF OLIVE OIL FOR JUST A BUCK GET YOUR $39 BOTTLE FOR JUST $1 NOTICE OF DISCLOSURE: Paid sponsorship DELIVERED TO YOUR DOOR – WITH FREE SHIPPING Use coupon code LLVLC for $200 OFF LINKS MENTIONED IN EPISODE 1319 – SUPPORT OUR SPONSOR: Get all the nutritious vegetables you need with Dr. Cowan's Garden ("JIMMY" at checkout to get 20% off your first order!) – SUPPORT OUR SPONSOR: The world’s freshest and most flavorful artisanal olive oils. Get your $39 bottle for just $1 – SUPPORT OUR SPONSOR: Love your tummy with Atrantil. (Get 15% off with the coupon code “JIMMY”) – SUPPORT OUR SPONSOR: Join The Keto Clarity Club For $1 Blood Ketone Test Strips! BestKetoneTest.com – Ivor Cummins bio – “The Fat Emperor” blog – VIDEO: The Cholesterol Conundrum – and Root Cause Solution – “The Cholesterol Conundrum” slide presentation – VIDEO: SUGAR As A Primary Root Cause of Metabolic Syndrome and the Obesity/Diabetes Epidemic – “Sugar As A Primary Root Cause Of Metabolic Syndrome And The Obesity/Diabetes Epidemic” slide presentation – Ivor Cummins on Facebook – Ivor Cummins on Twitter – Ivor Cummins’ YouTube Channel

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1315: Dr. Jacob Wilson And Ryan Lowery Preaching The Keto Gospel In The Ketogenic Bible

Play Episode Listen Later Sep 25, 2017 54:50

Authors and Ketogenic Researchers Dr. Jacob Wilson and Ryan Lowery are our interview guests today in Episode 1315 of “The Livin’ La Vida Low-Carb Show.” As you know, The ketogenic diet is on fire this year as more and more people become familiar with this powerful dietary approach that has proven effectiveness for conditions ranging from obesity and type 2 diabetes to Alzheimer's disease to cancer—not to mention its positive effects on athletic performance. In The Ketogenic Bible, Jacob Wilson and Ryan Lowery offer a comprehensive look at the ketogenic diet and the fat-burning state it induces, ketosis. It's the most complete source for information on keto—not only how to follow a ketogenic diet but also how it affects the bodily systems and processes that are at the core of how we feel and function every day. Their approach is based on the wide range of scientific research that’s been conducted on ketosis, including the research they're doing at their own Applied Science and Performance Institute. Through their work with people who are switching to a ketogenic diet, they also know the most common concerns and questions, so they've included practical tips and advice for following keto, along with more than 75 easy and delicious recipes. Listen in today as Jimmy talks with Dr. Jacob Wilson and Ryan Lowery about launching their book The Ketogenic Bible, the science and practical application behind the ketogenic diet, exogenous ketones, and all of their potential applications, human performance, whether you can gain muscle and lose fat on a ketogenic diet, the newest, cutting edge research on longevity, potential impact for cognitive disorders (Alzheimer’s, Parkinsons, and TBI), and much more. NATURAL BLOATING RELIEF GO TO LOVEMYTUMMY.COM USE COUPON CODE “JIMMY” FOR 15% OFF NOTICE OF DISCLOSURE: Paid sponsorship GET A $39 BOTTLE OF OLIVE OIL FOR JUST A BUCK GET YOUR $39 BOTTLE FOR JUST $1 NOTICE OF DISCLOSURE: Paid sponsorship DELIVERED TO YOUR DOOR – WITH FREE SHIPPING Use coupon code LLVLC for $200 OFF Join The Keto Clarity Club For $1 Blood Ketone Test Strips! LINKS MENTIONED IN EPISODE 1315 – SUPPORT OUR SPONSOR: The world’s freshest and most flavorful artisanal olive oils. Get your $39 bottle for just $1 – SUPPORT OUR SPONSOR: Love your tummy with Atrantil. (Get 15% off with the coupon code “JIMMY”) – SUPPORT OUR SPONSOR: Join The Keto Clarity Club For $1 Blood Ketone Test Strips! BestKetoneTest.com – Ryan Lowery on Twitter – Dr. Jacob Wilson on Twitter – The Ketogenic Bible

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1314: LLVLC Classic – Morley Robbins Underscores The Critical Importance Of Magnesium

Play Episode Listen Later Sep 20, 2017 45:48

Wellness coach, certified nutrition educator and bona fide magnesium expert Morley Robbins is our interview guest today in Episode 1314 of “The Livin’ La Vida Low-Carb Show.” As a hospital executive for over 30 years, Morley Robbins became disenchanted with the “revolving door mentality” of these “illness maintenance” enterprises. He has dedicated the remainder of his career to “saving one starfish at a time” by coaching clients how to eat “real food” and thereby facilitating the process of natural healing. We all know there are benefits to getting adequate amount of vitamins and minerals into our diets through both the foods we eat as well as added supplementation. However, many people neglect the importance of certain critical micronutrients that they need in their bodies to function as optimally healthy as possible. That’s a message that Morley “Magnesium Man” Robbins is seeking to convey to the public regarding the subject of magnesium. While Vitamin D and Vitamin C get most of the headlines these days when it comes to their importance on human health, Morley makes the argument that magnesium deserves a place at the table of discussion within the context of gaining health. Listen in as Jimmy and Morley talk about this lesser-known but incredibly important nutrient that everyone needs to be more aware of getting adequate amounts of in their diet. ENJOY! GET A $39 BOTTLE OF OLIVE OIL FOR JUST A BUCK GET YOUR $39 BOTTLE FOR JUST $1 NOTICE OF DISCLOSURE: Paid sponsorship NATURAL BLOATING RELIEF GO TO LOVEMYTUMMY.COM USE COUPON CODE “JIMMY” FOR 15% OFF NOTICE OF DISCLOSURE: Paid sponsorship JIMMY AND DR. ADAM NALLY’S KETO LIVING SUPPLEMENTS LINKS MENTIONED IN EPISODE 1310 – JIMMY AND DR. ADAM NALLY’S NEW SUPPLEMENT LINE: Try the KetoEssentials Multivitamin and Berberine Plus ketogenic-enhancing supplements – SUPPORT OUR SPONSOR: The world’s freshest and most flavorful artisanal olive oils. Get your $39 bottle for just $1 – SUPPORT OUR SPONSOR: Love your tummy with Atrantil. (Get 15% off with the coupon code “JIMMY”) – Morley Robbins bio – “Magnesium Man” web site – Morley Robbins on YouTube

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1310: LLVLC Classic – Nina Teicholz Bringing Healthy Saturated Fat Back Into Favor

Dr. Berkson's Best Health Radio Podcast

Play Episode Listen Later Sep 12, 2017 102:27

Investigative journalist and New York Times bestselling author Nina Teicholz is our guest today in Episode 1310 of “The Livin’ La Vida Low-Carb Show.” Every five years, the United States Department of Agriculture (USDA) convenes a panel of experts on nutrition and health called the Dietary Guidelines Advisory Committee to determine the Dietary Guidelines for Americans. But for investigative journalist Nina Teicholz, author of the New York Times bestselling book The Big Fat Surprise: Why Butter, Meat, and Cheese Belong in a Healthy Diet, she’s concerned that that general public is not being told about the incremental move towards a vegan diet. Today’s interview guest is an investigative journalist named Nina Teicholz who has written columns for Gourmet magazine, The New Yorker, The Economist, The New York Times, and The Washington Post. After being asked by a publisher to write a book about the health impact of trans fats over a decade ago, Teicholz found a much deeper story that was more salacious and groundbreaking than even she realized at the time–the negative attention saturated fat receives as a culprit in disease was just plain wrong and the unfounded low-fat diet advice has been the most disastrous public health experiment in world history. The culmination of over a decade of research and writing has resulted in the release of her 2014 book The Big Fat Surprise: Why Butter, Meat and Cheese Belong in a Healthy Diet that has already hit the New York Times bestsellers list. Listen in to hear Jimmy and Nina discuss the latest disturbing developments with the Dietary Guidelines, the differences between her book and Gary Taubes’ classic Good Calories, Bad Calories, the history behind how the American Heart Association bought into the anti-saturated fat bias of Ancel Keys, how the anti-sugar work of John Yudkin was mocked and ridiculed by anti-fat proponents, the fraudulent way the Mediterranean diet was created (by Keys) and marketed as “healthy,” how the vilification of tropical oils like coconut oil actually led to the increased use of trans fats, how groups like the Center for the Science in the Public Interest led by Michal Jacobson have had such an influence with good and bad results, the problem with omega-6-rich polyunsaturated fats from vegetable oils producing oxidation products when heated, and so much more! This new book from Nina Teicholz takes the message of Taubes to the next level in a narrative form that makes the notion of a high-fat diet more mainstream that it’s ever been before. The tide is turning and this book is going to be a big reason why. GET A $39 BOTTLE OF OLIVE OIL FOR JUST A BUCK GET YOUR $39 BOTTLE FOR JUST $1 NOTICE OF DISCLOSURE: Paid sponsorship NATURAL BLOATING RELIEF GO TO LOVEMYTUMMY.COM USE COUPON CODE “JIMMY” FOR 15% OFF NOTICE OF DISCLOSURE: Paid sponsorship JIMMY AND DR. ADAM NALLY’S KETO LIVING SUPPLEMENTS ORGANIC BRANDS YOU LOVE FOR LESS THRIVEMARKET.COM/KETO FOR 25% OFF NOTICE OF DISCLOSURE: Paid sponsorship LINKS MENTIONED IN EPISODE 1310 – SUPPORT OUR SPONSOR: Organic brands you love for less at thrivemarket.com/keto – JIMMY AND DR. ADAM NALLY’S NEW SUPPLEMENT LINE: Try the KetoEssentials Multivitamin and Berberine Plus ketogenic-enhancing supplements – SUPPORT OUR SPONSOR: The world’s freshest and most flavorful artisanal olive oils. Get your $39 bottle for just $1 – SUPPORT OUR SPONSOR: Love your tummy with Atrantil. (Get 15% off with the coupon code “JIMMY”) – Nina Teicholz bio – The Big Fat Surprise: Why Butter, Meat and Cheese Belong in a Healthy Diet – Jimmy Moore’s review of The Big Fat Surprise – The Big Fat Surprise official website – Nina on Twitter – The Questionable Link Between Saturated Fat and Heart Disease – VIDEO: ‘The Big Fat Surprise’ Rocks the Health Food World on “Good Morning America” – VIDEO: Nina Teicholz at TEDxEast: The Big Fat Surprise

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Functional gastroenterologist Dr. Kenneth Brown (#73)

Play Episode Listen Later Sep 8, 2017 83:59

Functional gastroenterologist Dr. Kenneth Brown, looks at the bigger picture including food and herbs to heal America’s ill guts. The gut has been called the 2nd brain, the mother ship of our health, the seat of our immune system, and the place where we get our authentic gut instinct—if all is working well. But if your gut is ill, “all” of you can feel miserable. This is difficult to appreciate if you haven’t experienced serious gut issues. But millions have. 60-70 million Americans suffer with gastrointestinal disease 240,000 deaths yearly from severe gastrointestinal disease (this number is similar to the number of breast cancer diagnoses in 2016 and double that of colon cancer) $141 billion dollars was spent in 2004 on gut illness Health starts in the gut. Many respectable research institutions are proclaiming and demonstrating this. But Americans are having more and more gut issues and worse and worse overall health. We have the first generation of kids who are forecasted to die earlier than their parent’s generation. Dr. Ken Brown admits that gastroenterology has insufficient tools to meet the demands and disease needs of our increasing ill Americans. That’s why he is the first gut doc, who used to design pharmaceuticals, to now recommend diet, herbs and even CBD oil. Dr. Ken Brown received his medical degree from the University of Nebraska Medical School, and completed his fellowship in Gastroenterology in San Antonio Texas. He is a board certified gastroenterologist who has been in practice for the past 15 years. His clinical focus has been on inflammatory bowel disease and irritable bowel syndrome. For the last 10 years Dr. Brown has been conducting clinical research for various pharmacologic companies. During this time, he saw the unmet need for something natural that could help his IBS patients find real relief. After working on the development of Atrantil for over 6 years Atrantil launched in 2015. Dr. Brown and his research team developed Atrantil with the intent of helping those suffering from the symptoms of IBS which we now know are caused by bacterial overgrowth. Dr. Brown shares how the application of Atrantil has expanded (when combined with diet, other herbs and functional medicine protocols) to include inflammatory bowel disease as well as a bucket list of other serious gut conditions often thought to either have no answers or require life long meds or surgery. Dr. Brown shares that he regularly gets his patients off drugs or into remission, rather rapidly, by these natural means, without meds or surgery. This is a dynamic, informative and inspiring 1-1/2 hour show. To purchase Atrantil: go to lovemytummy.com/berkson And use the code “berkson” at checkout to get 10% off + free shipping! Lastly, take a look at this fun Atrantil video!

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1307: LLVLC Classic – Dr. Datis Kharrazian Uses Functional Medicine To Treat Thyroid & Brain Issues

Lets Truck with Kevin Rutherford

Play Episode Listen Later Sep 5, 2017 102:06

Natural medicine practitioner and author Dr. Datis Kharrazian is our guest today in Episode 1307 of “The Livin’ La Vida Low-Carb Show.” How many people are dealing with the negative effects of dysfunctional brain function these days? From a total lack of concentration, brain fog, afternoon fatigue and a general sense of things not being quite right in the heard, it’s an all-too-common issue people just tolerate or medicate to deal with it. But today’s podcast interview guest says there are some very easy things people can do right now to take back control of their brain health for good. Health educator Dr. Datis Kharrazian from DrKNews.com, who specializes in sharing non-pharmaceutical applications to chronic illnesses, autoimmune disorders, and complex neurological disorders to medical practitioners around the world, is back today sharing about his brand new book on this subject of brain health entitled Why Isn’t My Brain Working?: A Revolutionary Understanding of Brain Decline and Effective Strategies to Recover Your Brain’s Health. This book contains so much invaluable information that most physicians, unfortunately, don’t know about regarding their patients’ brain health. Listen in as Jimmy and Dr. Kharrazian discuss the critical role nutrition and other lifestyle factors play in issues with the brain, gut, and overall health, his foray into nutrition and natural medicine, his frustration with the pharmaceutical model of treating disease, why the prescription drug industry is leading to a shutdown of various bodily functions, how the food solution is often times ignored by mainstream medical professionals although the public is beginning to educate themselves more, what the thyroid gland is and the function it serves. This one is an absolute MUST-LISTEN! NATURAL BLOATING RELIEF GO TO LOVEMYTUMMY.COM USE COUPON CODE “JIMMY” FOR 15% OFF NOTICE OF DISCLOSURE: Paid sponsorship JIMMY AND DR. ADAM NALLY’S KETO LIVING SUPPLEMENTS ORGANIC BRANDS YOU LOVE FOR LESS THRIVEMARKET.COM/KETO FOR 25% OFF NOTICE OF DISCLOSURE: Paid sponsorship GET A $39 BOTTLE OF OLIVE OIL FOR JUST A BUCK GET YOUR $39 BOTTLE FOR JUST $1 NOTICE OF DISCLOSURE: Paid sponsorship LINKS MENTIONED IN EPISODE 1307 – SUPPORT OUR SPONSOR: Organic brands you love for less at thrivemarket.com/keto – JIMMY AND DR. ADAM NALLY’S NEW SUPPLEMENT LINE: Try the KetoEssentials Multivitamin and Berberine Plus ketogenic-enhancing supplements – SUPPORT OUR SPONSOR: The world’s freshest and most flavorful artisanal olive oils. Get your $39 bottle for just $1 – SUPPORT OUR SPONSOR: Love your tummy with Atrantil. (Get 15% off with the coupon code “JIMMY”) – Dr. Datis Kharrazian bio – Why Isn’t My Brain Working?: A Revolutionary Understanding of Brain Decline and Effective Strategies to Recover Your Brain’s Health

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DH 123 | August 30 |

Destination Health

Play Episode Listen Later Aug 30, 2017 100:32

Our guest on the show is Dr. Kenneth Brown creator of Atrantil, also a Board Certified Gastroenterologist. ATRANTÍL CHANGES THE CYCLE NATURALLY—AND GETS YOUR DIGESTION BACK ON TRACK - For millions, bloating and abdominal discomfort sometimes accompanied by a change in bowel habits make life miserable. New research shows that the problems start with methane-producing bacteria is present where it shouldn't be. Left untreated, these out-of-place bacteria feed off the foods you eat and create methane gas that can leave you bloated and uncomfortable. The problem isn't all in your mind - it's in your digestive tract. Atrantil:https://letstruck.com/collect…/supplements/products/atrantil Leaky Gut Kit: 15day or 30 dayhttps://letstruck.com/products/leaky-gut-kit…

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August 30 | Trucking: DestinationHealth

Play Episode Listen Later Aug 30, 2017 100:46

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1303: Dr. Ashley Lucas Explains Why Weight Regain Is So Common After Weight Loss

Play Episode Listen Later Aug 28, 2017 43:40

Ph.D. in sports nutrition and chronic disease, and registered dietitian Dr. Ashley Lucas is our guest today in Episode 1303 of The Livin’ La Vida Low-Carb Show with Jimmy Moore. One of the most frustrating experiences is losing a significant amount of weight only to have it creep back on. On today's show, Jimmy talks with Dr. Ashley Lucas from phdadvancednutrition.com about this very problem. From her own athletic background, Dr. Lucas began her career in sports nutrition working with athletes nationwide in optimizing performance and body composition, but quickly found a passion in nutrition for obesity related issues. Referencing studies dated from the 1800’s that successfully treated the (then rare) cases of obesity, without medications, fad-dieting, severe caloric restrictions, or chronic levels of exercise, she developed a new protocol for individuals battling the continuous weight gain of today’s society. Her scientific approach focuses not only on the metabolic consequences of fat gain, but also on the behavioral and psychological aspects. The PHD approach to achieving optimal weight is truly life changing, and one that is helping people across the country achieve their peak wellness once and for all. Listen in today as Jimmy talks with Dr. Lucas about how to keep weight off once weight loss goals have been achieved and why weight regain is so prevalent, common mental barriers during weight loss, what it takes from a program stand point to see true success with weight loss and maintenance, clinical benefits from low carb eating she's witnessed (reversal of type 2 diabetes, HTN, fatty liver, skin conditions, GERD, sleep, clean teeth and so much more), exercise more as a wellness tool, eating everything in moderation doesn’t work for everybody, and sport performance and low carb living JIMMY AND DR. ADAM NALLY’S KETO LIVING SUPPLEMENTS ORGANIC BRANDS YOU LOVE FOR LESS THRIVEMARKET.COM/KETO FOR 25% OFF NOTICE OF DISCLOSURE: Paid sponsorship GET A $39 BOTTLE OF OLIVE OIL FOR JUST A BUCK GET YOUR $39 BOTTLE FOR JUST $1 NOTICE OF DISCLOSURE: Paid sponsorship NATURAL BLOATING RELIEF GO TO LOVEMYTUMMY.COM USE COUPON CODE “JIMMY” FOR 15% OFF NOTICE OF DISCLOSURE: Paid sponsorship LINKS MENTIONED IN EPISODE 1303 – SUPPORT OUR SPONSOR: Organic brands you love for less at thrivemarket.com/keto – JIMMY AND DR. ADAM NALLY’S NEW SUPPLEMENT LINE: Try the KetoEssentials Multivitamin and Berberine Plus ketogenic-enhancing supplements – SUPPORT OUR SPONSOR: The world’s freshest and most flavorful artisanal olive oils. Get your $39 bottle for just $1 – SUPPORT OUR SPONSOR: Love your tummy with Atrantil. (Get 15% off with the coupon code “JIMMY”) – phdadvancednutrition.com

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1302: LLVLC Classic – Dr. Peter Attia On Eating A Low-Insulin Diet

Play Episode Listen Later Aug 23, 2017 149:06

Medical doctor and nutrition science blogger Dr. Peter Attia is our guest today in Episode 1302 of The Livin’ La Vida Low-Carb Show with Jimmy Moore. In this LLVLC Classic episode, we bring you one of the premier voices in the low-carb, high-fat community. Dr. Peter Attia from EatingAcademy.com was a typical medical doctor who was trained well in prescribing medications for a variety of chronic diseases. But he decided the typical high-carb, low-fat diet he was on was not optimal for managing his weight and health and he embarked on an incremental journey to start livin’ la vida low-carb. First he cut sugar, then other white carbohydrates, then starchy carbohydrates and finally cut carbs down to 50g daily along with reducing protein to 120g per day. The result was lower body fat, improved cardiovascular markers and a marked improvement in his athletic performance. Dr. Attia also believes that people should find a diet plan that works for them and stick to it, finding that consistency is key. Listen in today as Jimmy and Dr. Attia talk about what he learned about nutrition in medical school, how he found himself overweight and felt like he was doing everything right, setting out to find what the problem was, why low-carb is not a 'silly fad', doctors who thought he was “crazy” but were open-minded, “unnecessary human suffering” that takes place prior to death, the trend in newer studies focusing on calories are deceptive, the JAMA study from Pennington researchers in January 2012, and much more in this exciting episode. ORGANIC BRANDS YOU LOVE FOR LESS THRIVEMARKET.COM/KETO FOR 25% OFF NOTICE OF DISCLOSURE: Paid sponsorship GET A $39 BOTTLE OF OLIVE OIL FOR JUST A BUCK GET YOUR $39 BOTTLE FOR JUST $1 NOTICE OF DISCLOSURE: Paid sponsorship NATURAL BLOATING RELIEF GO TO LOVEMYTUMMY.COM USE COUPON CODE “JIMMY” FOR 15% OFF NOTICE OF DISCLOSURE: Paid sponsorship JIMMY AND DR. ADAM NALLY’S KETO LIVING SUPPLEMENTS LINKS MENTIONED IN EPISODE 1302 – SUPPORT OUR SPONSOR: Organic brands you love for less at thrivemarket.com/keto – JIMMY AND DR. ADAM NALLY’S NEW SUPPLEMENT LINE: Try the KetoEssentials Multivitamin and Berberine Plus ketogenic-enhancing supplements – SUPPORT OUR SPONSOR: The world’s freshest and most flavorful artisanal olive oils. Get your $39 bottle for just $1 – SUPPORT OUR SPONSOR: Love your tummy with Atrantil. (Get 15% off with the coupon code “JIMMY”) – Dr. Peter Attia's EatingAcademy.com

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1298: LLVLC Classic – Dr. Richard Johnson Finds Fructose Turns On The Fat Switch

Play Episode Listen Later Aug 15, 2017 44:00

Professor of medicine and fructose obesity researcher Dr. Richard Johnson is our guest today in Episode 1298 of The Livin’ La Vida Low-Carb Show with Jimmy Moore! In this LLVLC Classic Episode, Jimmy chats with Dr. Richard Johnson from the University of Colorado Denver as a follow up to Dr. Johnson's first appearance in Episode 223 of the podcast in January 2009 discussing his book The Sugar Fix where he hypothesized that fructose alone was the root cause behind obesity and chronic disease, Jimmy challenged him about his theory during that interview encouraging him to examine the role of ALL carbohydrates on metabolic health. And so he did. Dr. Johnson returned to discuss his newfound support for low-carb nutrition in his book titled The Fat Switch published by the great online health advocate Dr. Joseph Mercola. Listen in today as Jimmy and Dr. Johnson discuss what he found when he started researching how carbohydrates respond in the body, what led him to shift his views on the cause of obesity from fructose to all carbohydrates, and what it takes to turn on and off the “fat switch.” This is a fantastic conversation you’ll enjoy from one of the world’s top obesity researchers. ORGANIC BRANDS YOU LOVE FOR LESS THRIVEMARKET.COM/KETO FOR 25% OFF NOTICE OF DISCLOSURE: Paid sponsorship NATURAL BLOATING RELIEF GO TO LOVEMYTUMMY.COM USE COUPON CODE “JIMMY” FOR 15% OFF NOTICE OF DISCLOSURE: Paid sponsorship JIMMY AND DR. ADAM NALLY’S KETO LIVING SUPPLEMENTS GET A $39 BOTTLE OF OLIVE OIL FOR JUST A BUCK GET YOUR $39 BOTTLE FOR JUST $1 NOTICE OF DISCLOSURE: Paid sponsorship LINKS MENTIONED IN EPISODE 1298 – SUPPORT OUR SPONSOR: Organic brands you love for less at thrivemarket.com/keto – JIMMY AND DR. ADAM NALLY’S NEW SUPPLEMENT LINE: Try the KetoEssentials Multivitamin and Berberine Plus ketogenic-enhancing supplements – SUPPORT OUR SPONSOR: The world’s freshest and most flavorful artisanal olive oils. Get your $39 bottle for just $1 – SUPPORT OUR SPONSOR: Love your tummy with Atrantil. (Get 15% off with the coupon code “JIMMY”) – Dr. Richard Johnson bio – FructoseDoctor.com – Official web site for The Fat Switch

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1294: Model Crosby Tailor Brings Keto To Mainstream On Food Network's "Chopped"

Play Episode Listen Later Aug 7, 2017 61:35

Model, health coach and Food Network "Chopped" contestant Crosby Tailor is our guest today in Episode 1294 of The Livin’ La Vida Low-Carb Show with Jimmy Moore! Crosby Tailor from TailordLife.com is a represented fashion model and graduated college football athlete turned health coach, biohacker and sugar-free dessert chef. He studied Chinese tonics herbs under mentors Ron Teaguarden of Dragonherbs, and George Lamoreaux of Jing Herbs, as well as mastered the art of biohacking with the help of Dave Asprey of Bulletproof. Crosby is a very strong advocate of the keto world and started making sugar-free keto desserts, which he eventually called Eat Dessert Burn Fat! Recently, Crosby founded a breathwork and meditation group with 3 others that they named The Wildfire Initiative and its growing like “wildfire!” Crosby has been featured in US Vogue & Elle Magazine, Business Insider, NY Mag The Cut, Well and Good, Health.com, The London Times, and was even a contestant on Food Networks Chopped where Crosby made high fat keto meals! Listen in today as Jimmy chats with Crosby Tailor about his journey from model to health coach, and now to Food Network Star. ORGANIC BRANDS YOU LOVE FOR LESS THRIVEMARKET.COM/KETO FOR 25% OFF NOTICE OF DISCLOSURE: Paid sponsorship JIMMY AND DR. ADAM NALLY’S KETO LIVING SUPPLEMENTS GET A $39 BOTTLE OF OLIVE OIL FOR JUST A BUCK GET YOUR $39 BOTTLE FOR JUST $1 NOTICE OF DISCLOSURE: Paid sponsorship NATURAL BLOATING RELIEF GO TO LOVEMYTUMMY.COM USE COUPON CODE “JIMMY” FOR 15% OFF NOTICE OF DISCLOSURE: Paid sponsorship LINKS MENTIONED IN EPISODE 1294 – SUPPORT OUR SPONSOR: Organic brands you love for less at thrivemarket.com/keto – JIMMY AND DR. ADAM NALLY’S NEW SUPPLEMENT LINE: Try the KetoEssentials Multivitamin and Berberine Plus ketogenic-enhancing supplements – SUPPORT OUR SPONSOR: The world’s freshest and most flavorful artisanal olive oils. Get your $39 bottle for just $1 – SUPPORT OUR SPONSOR: Love your tummy with Atrantil. (Get 15% off with the coupon code “JIMMY”) – TailordLife.com – Crosby Tailor Instagram

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1293: Gunnar Lovelace Changes The Organic Food Game With Thrive Market

Play Episode Listen Later Aug 2, 2017 28:46

Founder and co-CEO of Thrive Market Gunnar Lovelace is our guest today in Episode 1292 of The Livin’ La Vida Low-Carb Show with Jimmy Moore! As a listener of The Livin' La-Vida Low-Carb Show, you understand just how important it is to have readily available quality foods. And thankfully, this mindset is growing by leaps and bounds, so much so that it has given rise to supermarket chains like the 800 pound gorilla on the block Whole Foods. But as the joke goes, Whole Foods can feel more like "Whole Paycheck". Our guest today, Gunnar Lovelace from ThriveMarket.com watched his mother struggle to provide his family with quality food on a budget and he made it one of his missions to find a way to make quality food affordable. Listen in today as Jimmy talks with Gunnar about the mission of Thrive Market and what that means to him personally, why he sees passion for quality food as more important to younger generations, how Thrive Market keeps their prices low, providing more than just food for a healthy lifestyle, how Thrive Market gives back to the community and much more. ORGANIC BRANDS YOU LOVE FOR LESS THRIVEMARKET.COM/KETO FOR 25% OFF NOTICE OF DISCLOSURE: Paid sponsorship JIMMY AND DR. ADAM NALLY’S KETO LIVING SUPPLEMENTS GET A $39 BOTTLE OF OLIVE OIL FOR JUST A BUCK GET YOUR $39 BOTTLE FOR JUST $1 NOTICE OF DISCLOSURE: Paid sponsorship NATURAL BLOATING RELIEF GO TO LOVEMYTUMMY.COM USE COUPON CODE “JIMMY” FOR 15% OFF NOTICE OF DISCLOSURE: Paid sponsorship LINKS MENTIONED IN EPISODE 1293 – SUPPORT OUR SPONSOR: Organic brands you love for less at thrivemarket.com/keto – JIMMY AND DR. ADAM NALLY’S NEW SUPPLEMENT LINE: Try the KetoEssentials Multivitamin and Berberine Plus ketogenic-enhancing supplements – SUPPORT OUR SPONSOR: The world’s freshest and most flavorful artisanal olive oils. Get your $39 bottle for just $1 – SUPPORT OUR SPONSOR: Love your tummy with Atrantil. (Get 15% off with the coupon code “JIMMY”) – ThriveMarket.co/Keto – Gunnar Lovelace LinkedIn

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1288: Karen Thomson and Emily Maguire Teach How You Can Beat Sugar And Carb Addiction In 28 Days

Play Episode Listen Later Jul 24, 2017 36:13

South African anti-sugar troubadour and recovering addict Karen Thomson and Scottish ketogenic nutritional health expert Emily Maguire are our guests today in Episode 1288 of “The Livin’ La Vida Low-Carb Show.” We all know how difficult sugar and carb addiction can be, and for a lot of people there are underlying emotional and psychological issues that go deeper than nutrition alone can address. Our guests today Karen Thomson from TheSugarFreeRevolution.com and Emily Maguire from LowCarbGenesis.com have created a 28 day Sugar Free Lifestyle video course that will empower individuals to beat their sugar and carb addiction by addressing these issues. The Challenge is a 28 Day Lifestyle Reset (not a diet), that aims to help people regain control over their cravings, feel super human, and reverse the progression of chronic, preventable diseases. Listen in today as Jimmy talks with Karen and Emily about getting to the root of what makes us turn to unhealthy foods and behaviors. They share about Karen and Emily's new video series that is all about combating sugar addiction focuses and addressing these underlying issues that drive the addiction, why traditionally trained nutritionists focus on cutting fat, the misinterpretations of data in the medical establishment, why we need people to bring clarity to the popular dietary advice, how people can implement their program into their real lives, why we need the support of others, why real, whole foods matter, treating food addictions the same way you treat chemical addictions, dealing with guilt and shame, the future of dietary guidelines, and much more. SUPERFOODS YOU SHOULD NEVER EAT NOTICE OF DISCLOSURE: Paid sponsorship THE PERFECT KETO SUPPLEMENT USE COUPON CODE LLVLC FOR 15% OFF NOTICE OF DISCLOSURE: Paid sponsorship NATURAL BLOATING RELIEF GO TO LOVEMYTUMMY.COM USE COUPON CODE “JIMMY” FOR 15% OFF NOTICE OF DISCLOSURE: Paid sponsorship WORLD’S 1ST REUSABLE BREATH KETONE ANALYZER NOTICE OF DISCLOSURE: Paid sponsorship LINKS MENTIONED IN EPISODE 1288 – SUPPORT OUR SPONSOR: GetEnergy53.com – SUPPORT OUR SPONSOR: Jump start your ketogenic diet with PerfectKeto.com/Jimmy (USE PROMO CODE LLVLC FOR 15% OFF) – SUPPORT OUR SPONSOR: Love your tummy with Atrantil. (Get 15% off with the coupon code “JIMMY”) – SUPPORT OUR SPONSOR: Get the BRAND NEW 2017 Ketonix breath ketone analyzer from Ketonix.com – Karen Thomson bio – Emily Maguire bio – Karen on Twitter – Emily Maguire on Twitter – Emily on Instagram – RELATED PODCAST: The LLVLC Show #998: Karen Thomson And Emily Maguire On The Sugar Free September Challenge – TheSugarFreeRevolution.com/Challenge/ – TheSugarFreeRevolution.com – LowCarbGenesis.com

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1287: Andreas Eenfeldt – 2016 Low-Carb USA

Play Episode Listen Later Jul 19, 2017 54:07

Swedish physician and low-carb, high-fat diet advocate Dr. Andreas Eenfeldt is our special 2016 Low Carb USA guest speaker featured in Episode 1287 of “The Livin’ La Vida Low-Carb Show.” Low Carb USA™ is an organization focused on dietary education and support by hosting scientific conferences, providing online coaching and mentoring, and legislative efforts. Low Carb USA™, founded in 2015, hosts educational public conferences at which scientists and doctors present their latest research findings into nutrition and the low-carb lifestyle. Online coaching and mentoring forums are offered to help people learn how to adopt this lifestyle and change their lives. A new initiative is also underway to support a unified coalition of communities advocating science based nutrition advice to influence the USDA to modify dietary guidelines using evidence-based research. For this effort, Low Carb USA™ is joining forces with journalist Nina Teicholz, author of the best-selling book The Big Fat Surprise and the Nutrition Coalition. In July of 2016, they brought together the world’s top medical and scientific minds on how nutrition can treat and prevent serious disease at the largest-ever low-carb conference. JOIN US IN SAN DIEGO, CA ON AUGUST 3-6, 2017 Listen in to hear various lectures from that conference on “The Livin’ La Vida Low-Carb Show” podcast all month long to give you a taste of what this event was all about. Today’s lecture is from a Swedish physician and low-carb, high-fat diet advocate named Dr. Andreas Eenfeldt from DietDoctor.com. He will be sharing his lecture titled “A Global Food Revolution”. And if listening to these lectures gets you excited about attending the Low Carb USA conference coming up August 3-6, 2017 in San Diego California, then GET YOUR TICKETS NOW for this awesome event featuring lots of familiar names and maybe a few new ones as guest speakers who will share more of their knowledge for you to soak in. This conference is great cross between the really science-heavy conferences and the consumer-driven ones for the perfect balance of education and inspiration in your own low-carb lifestyle! Our host Jimmy Moore is excited to be speaking there again this year and hopes to see you there. THE PERFECT KETO SUPPLEMENT USE COUPON CODE LLVLC FOR 15% OFF NOTICE OF DISCLOSURE: Paid sponsorship NATURAL BLOATING RELIEF GO TO LOVEMYTUMMY.COM USE COUPON CODE “JIMMY” FOR 15% OFF NOTICE OF DISCLOSURE: Paid sponsorship WORLD’S 1ST REUSABLE BREATH KETONE ANALYZER NOTICE OF DISCLOSURE: Paid sponsorship SUPERFOODS YOU SHOULD NEVER EAT NOTICE OF DISCLOSURE: Paid sponsorship LINKS MENTIONED IN EPISODE 1287 – SUPPORT OUR SPONSOR: Jump start your ketogenic diet with PerfectKeto.com/Jimmy (USE PROMO CODE LLVLC FOR 15% OFF) – SUPPORT OUR SPONSOR: Love your tummy with Atrantil. (Get 15% off with the coupon code “JIMMY”) – SUPPORT OUR SPONSOR: Get the BRAND NEW 2017 Ketonix breath ketone analyzer from Ketonix.com – SUPPORT OUR SPONSOR: GetEnergy53.com – DietDoctor.com – Low Carb USA conference coming up August 3-6, 2017 in San Diego California, GET YOUR TICKETS NOW

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1283: Dr. Salih Solomon – 2016 Low-Carb USA

Play Episode Listen Later Jul 11, 2017 19:14

Member of The Noakes Foundation Dr. Salih Solomon is our special 2016 Low Carb USA guest speaker featured in Episode 1283 of “The Livin’ La Vida Low-Carb Show.” [powerpress] LISTEN AND DOWNLOAD AT ITUNES Low Carb USA™ is an organization focused on dietary education and support by hosting scientific conferences, providing online coaching and mentoring, and legislative efforts. Low Carb USA™, founded in 2015, hosts educational public conferences at which scientists and doctors present their latest research findings into nutrition and the low-carb lifestyle. Online coaching and mentoring forums are offered to help people learn how to adopt this lifestyle and change their lives. A new initiative is also underway to support a unified coalition of communities advocating science based nutrition advice to influence the USDA to modify dietary guidelines using evidence-based research. For this effort, Low Carb USA™ is joining forces with journalist Nina Teicholz, author of the best-selling book The Big Fat Surprise and the Nutrition Coalition. In July of 2016, they brought together the world’s top medical and scientific minds on how nutrition can treat and prevent serious disease at the largest-ever low-carb conference. JOIN US IN SAN DIEGO, CA ON AUGUST 3-6, 2017 Listen in to hear various lectures from that conference on “The Livin’ La Vida Low-Carb Show” podcast all month long to give you a taste of what this event was all about. Today’s lecture is from member of The Noakes Foundation, Dr. Salih Solomon. He will be sharing his lecture titled “How to Change the Way a Country Eats”. And if listening to these lectures gets you excited about attending the Low Carb USA conference coming up August 3-6, 2017 in San Diego California, then GET YOUR TICKETS NOW for this awesome event featuring lots of familiar names and maybe a few new ones as guest speakers who will share more of their knowledge for you to soak in. This conference is great cross between the really science-heavy conferences and the consumer-driven ones for the perfect balance of education and inspiration in your own low-carb lifestyle! Our host Jimmy Moore is excited to be speaking there again this year and hopes to see you there. NATURAL BLOATING RELIEF GO TO LOVEMYTUMMY.COM USE COUPON CODE “JIMMY” FOR 15% OFF NOTICE OF DISCLOSURE: Paid sponsorship WORLD’S 1ST REUSABLE BREATH KETONE ANALYZER NOTICE OF DISCLOSURE: Paid sponsorship SUPERFOODS YOU SHOULD NEVER EAT NOTICE OF DISCLOSURE: Paid sponsorship THE PERFECT KETO SUPPLEMENT USE COUPON CODE LLVLC FOR 15% OFF NOTICE OF DISCLOSURE: Paid sponsorship LINKS MENTIONED IN EPISODE 1279 – SUPPORT OUR SPONSOR: Love your tummy with Atrantil. (Get 15% off with the coupon code “JIMMY”) – SUPPORT OUR SPONSOR: Get the BRAND NEW 2017 Ketonix breath ketone analyzer from Ketonix.com – SUPPORT OUR SPONSOR: GetEnergy53.com – Low Carb USA conference coming up August 3-6, 2017 in San Diego California, GET YOUR TICKETS NOW

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1280: Peter Defty – 2016 Low-Carb USA

Play Episode Listen Later Jul 4, 2017 55:26

GM of VESPA, nutrition expert and ultra athlete Peter Defty is our special 2016 Low Carb USA guest speaker featured in Episode 1280 of “The Livin’ La Vida Low-Carb Show.” Low Carb USA™ is an organization focused on dietary education and support by hosting scientific conferences, providing online coaching and mentoring, and legislative efforts. Low Carb USA™, founded in 2015, hosts educational public conferences at which scientists and doctors present their latest research findings into nutrition and the low-carb lifestyle. Online coaching and mentoring forums are offered to help people learn how to adopt this lifestyle and change their lives. A new initiative is also underway to support a unified coalition of communities advocating science based nutrition advice to influence the USDA to modify dietary guidelines using evidence-based research. For this effort, Low Carb USA™ is joining forces with journalist Nina Teicholz, author of the best-selling book The Big Fat Surprise and the Nutrition Coalition. In July of 2016, they brought together the world’s top medical and scientific minds on how nutrition can treat and prevent serious disease at the largest-ever low-carb conference. JOIN US IN SAN DIEGO, CA ON AUGUST 3-6, 2017 Listen in to hear various lectures from that conference on “The Livin’ La Vida Low-Carb Show” podcast all month long to give you a taste of what this event was all about. Today’s lecture is from Peter Defty, GM of VESPA, nutrition expert and ultra athlete who developed a safe, healthy approach to fat adaption for endurance athletes called “Optimized Fat Metabolism” (OFM). Peter got into running circa 2000, going from carb burner with poor results to a fat burner with success in racing. He’ competed in the Western States 100, among many other events, and also coaches ultra athletes on using fat as fuel (Timothy Olson, Nikki Kimball, Zach Bitter, etc). He works with guys like Stephen Phinney, Jeff Volek, etc., on refining this approach for success in life and racing. “Winning On Fate”. And if listening to these lectures gets you excited about attending the Low Carb USA conference coming up August 3-6, 2017 in San Diego California, then GET YOUR TICKETS NOW for this awesome event featuring lots of familiar names and maybe a few new ones as guest speakers who will share more of their knowledge for you to soak in. This conference is great cross between the really science-heavy conferences and the consumer-driven ones for the perfect balance of education and inspiration in your own low-carb lifestyle! Our host Jimmy Moore is excited to be speaking there again this year and hopes to see you there. GET A $39 BOTTLE OF OLIVE OIL FOR JUST A BUCK GET YOUR $39 BOTTLE FOR JUST $1 NOTICE OF DISCLOSURE: Paid sponsorship NATURAL BLOATING RELIEF LOVEMYTUMMY.COM “JIMMY” FOR 15% OFF NOTICE OF DISCLOSURE: Paid sponsorship GIVE YOUR ELECTROLYTES A SUGAR-FREE BOOST USE COUPON CODE “LLVLC” FOR $10 OFF NOTICE OF DISCLOSURE: Paid sponsorship LINKS MENTIONED IN EPISODE 1280 – SUPPORT OUR SPONSOR: Go to JImmyKeto.com for delicious Keto friendly foods delivered to your door. (Get a $150 discount on any 28 day program when you use coupon code LLVLC) – SUPPORT OUR SPONSOR: The world’s freshest and most flavorful artisanal olive oils. Get your $39 bottle for just $1 – SUPPORT OUR SPONSOR: Love your tummy with Atrantil. (Get 15% off with the coupon code “JIMMY”) – SUPPORT OUR SPONSOR: Get the new lemon-lime flavored Jigsaw Electrolyte Supreme supplement (Get $10 off your order with coupon code “LLVLC”)

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1276: Franziska Spritzler – 2016 Low-Carb USA

Play Episode Listen Later Jun 26, 2017 49:28

Registered dietitian Franziska Spritzler is our special 2016 Low Carb USA guest speaker featured in Episode 1276 of “The Livin’ La Vida Low-Carb Show.” Low Carb USA™ is an organization focused on dietary education and support by hosting scientific conferences, providing online coaching and mentoring, and legislative efforts. Low Carb USA™, founded in 2015, hosts educational public conferences at which scientists and doctors present their latest research findings into nutrition and the low-carb lifestyle. Online coaching and mentoring forums are offered to help people learn how to adopt this lifestyle and change their lives. A new initiative is also underway to support a unified coalition of communities advocating science based nutrition advice to influence the USDA to modify dietary guidelines using evidence-based research. For this effort, Low Carb USA™ is joining forces with journalist Nina Teicholz, author of the best-selling book The Big Fat Surprise and the Nutrition Coalition. In July of 2016, they brought together the world’s top medical and scientific minds on how nutrition can treat and prevent serious disease at the largest-ever low-carb conference. JOIN US IN SAN DIEGO, CA ON AUGUST 3-6, 2017 Listen in as you will hear various lectures from that conference on “The Livin’ La Vida Low-Carb Show” podcast all month long to give you a taste of what this event was all about. Today’s lecture is from Franziska Spritzler, is a Registered Dietitian and Certified Diabetes Educator who takes a carbohydrate-restricted, whole-foods approach to managing diabetes and insulin resistance. She will be sharing her lecture titled “How to Achieve a Healthy Low Carb Lifestyle”. And if listening to these lectures gets you excited about attending the Low Carb USA conference coming up August 3-6, 2017 in San Diego California, then GET YOUR TICKETS NOW for this awesome event featuring lots of familiar names and maybe a few new ones as guest speakers who will share more of their knowledge for you to soak in. This conference is great cross between the really science-heavy conferences and the consumer-driven ones for the perfect balance of education and inspiration in your own low-carb lifestyle! Our host Jimmy Moore is excited to be speaking there again this year and hopes to see you there. GET A $39 BOTTLE OF OLIVE OIL FOR JUST A BUCK GET YOUR $39 BOTTLE FOR JUST $1 NOTICE OF DISCLOSURE: Paid sponsorship NATURAL BLOATING RELIEF LOVEMYTUMMY.COM “JIMMY” FOR 15% OFF NOTICE OF DISCLOSURE: Paid sponsorship GIVE YOUR ELECTROLYTES A SUGAR-FREE BOOST USE COUPON CODE “LLVLC” FOR $10 OFF NOTICE OF DISCLOSURE: Paid sponsorship LOW-CARB KETO FOODS FOR LESS THAN $15 A DAY– WITH FREE SHIPPING Use coupon code LLVLC for $150 OFF NOTICE OF DISCLOSURE: Paid sponsorship LINKS MENTIONED IN EPISODE 1276 – SUPPORT OUR SPONSOR: Love your tummy with Atrantil. (Get 15% off with the coupon code “JIMMY”) – SUPPORT OUR SPONSOR: Get the new lemon-lime flavored Jigsaw Electrolyte Supreme supplement (Get $10 off your order with coupon code “LLVLC”) – SUPPORT OUR SPONSOR: Go to JImmyKeto.com for delicious Keto friendly foods delivered to your door. (Get a $150 discount on any 28 day program when you use coupon code LLVLC) – SUPPORT OUR SPONSOR: The world’s freshest and most flavorful artisanal olive oils. Get your $39 bottle for just $1

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1275: Dr. Jacob Wilson – 2016 Low-Carb USA