Podcasts about nmn

Upgrade your week in just 10 minutes with D(AI)ve Asprey's essential rundown on what matters most in longevity, biohacking, AI health tech, and medical freedom. This episode covers: • Apple Cider Vinegar Myth Busted A weight-loss study just got retracted. ACV will not melt fat, but it may blunt glucose spikes or ease digestion when diluted in water before carb-heavy meals. Skip the shots and protect your teeth. Source: https://www.sciencedaily.com/releases/2025/10/251001092216.htm • NMN Is Back The FDA reversal puts NMN back on shelves as a clean NAD precursor. Dave explains why quality, cycling, and stacking with anti-inflammatory strategies make the difference. Source: https://www.prnewswire.com/news-releases/renue-by-science-celebrates-fda-reversal-confirming-nmn-is-lawful-for-use-in-dietary-supplements-302573317.html • Poor Sleep Ages Your Brain Machine learning MRI studies show poor sleep makes your brain biologically older and raises dementia risk. Dave shares the three dials to track (deep sleep, REM, resting heart rate) and the three biggest levers to fix them. Source: https://www.sciencedaily.com/releases/2024/10/241023171543.htm • Psilocybin for Lasting Reset New research finds a single guided dose can unlock plasticity, ease pain patterns, and lift mood for weeks. Dave outlines safe protocols, integration steps, and why it is a strategic reset tool, not a party trick. Source: https://www.sciencedaily.com/releases/2025/06/250616040215.htm • AI Detects Cancer Earlier A new AI tool called DOLPHIN can find hidden genetic markers to flag cancer risk sooner. Pairing high tech scans with low tech terrain fixes like sleep, muscle, and insulin control is the prevention model that works. Source: https://www.sciencedaily.com/releases/2025/10/251001092206.htm All source links provided for easy reference to the original reporting and research above. This is essential listening for fans of biohacking, hacking human performance, functional medicine, and longevity who want actionable tools from Host Dave Asprey and a guest who embodies what it means to age with energy, clarity, and vitality. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday (audio-only), and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: Apple cider vinegar, weight loss myths, NMN supplements, NAD precursors, cellular energy, sleep and dementia, brain aging, deep sleep optimization, REM sleep, psilocybin therapy, BDNF, neuroplasticity, pain relief, mood reset, AI cancer detection, early cancer screening, biohacking news, longevity science, Dave Asprey, Human Upgrade podcast Thank you to our sponsors! Screenfit | Get your at-home eye training program for 40% off using code DAVE https://www.screenfit.com/dave. LYMA | Go to https://lyma.sjv.io/gOQ545 and use code DAVE10 for 10% off the LYMA Laser. Vibrant Blue Oils | Grab a full-size bottle for over 50% off at https://vibrantblueoils.com/dave. Resources: • Danger Coffee: https://dangercoffee.com/discount/dave15 • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 — Introduction 0:18 — Story 1: Apple Cider Vinegar and Weight Loss 1:49 — Story 2: NMN is Back in Supplements 3:31 — Story 3: Sleep and Brain Health 5:39 — Story 4: Psilocybin and Lasting Relief 7:49 — Story 5: AI Tool DOLPHIN for Early Cancer Signals 9:48 — Conclusion & Weekly Roundup See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Extending our healthy years isn't just about eating well and exercising — it's also about the systems around us. Social policies, public health programs, and access to care all play a huge role in how long and how well we live. In this episode, we look at what it takes to improve health for everyone, everywhere. We each have personal choices to make, but what about the bigger picture?Dr. Tyler Evans is a physician, infectious disease specialist, and author of Pandemics, Poverty and Politics: Decoding the Social and Political Drivers of Pandemics from Plague to Covid-19.In a wide-ranging conversation with Peter Bowes, Dr. Evans connects stalled life expectancy to weakened safety nets, unequal access to healthcare, and the cracks exposed by recent global crises. He emphasizes practical action — meeting people where they are, funding prevention, and rebuilding systems that can spot and stop health threats early. Drawing on his experience from Los Angeles's Skid Row to global epidemic response, Evans calls for a non-partisan, evidence-driven approach that focuses on those most at risk — because when the most vulnerable communities thrive, everyone benefits.----This podcast is supported by affiliate arrangements with a select number of companies. We have arranged discounts on certain products and receive a small commission on sales. The income helps to cover production costs and ensures that our interviews remain free for all to listen. Visit our SHOP for more details: https://healthspan-media.com/live-long-podcast/shop/ PartiQlar supplementsEnhance your wellness journey with PartiQlar supplements. No magic formulas, just pure single ingredients, like NMN, L-Glutathione, Spermidine, Resveratrol, TMG and Quercetin. Get a 15% discount with the code MASTERAGING15 at PartiQlarEnergyBits algae snacksA microscopic form of life that could help us age better. Use code LLAMA for a 20 percent discountSiPhox Health home blood testingMeasure 17 critical blood biomarkers from home. Get a 20% discount with code LLAMA Disclaimer: This post contains affiliate links. If you make a purchase, I may receive a commission at no extra cost to you.Support the showThe Live Long and Master Aging (LLAMA) podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice. If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.

In this episode, Dr. Jones talks again with Dr. Paul Anderson, naturopathic doctor, researcher, and teacher. He joined the podcast last year to talk about cholesterol and lipid labs. This time the focus is on NAD (Nicotinamide Adenine Dinucleotide) and why it matters for your health.They explain what NAD does in the body, especially for energy, brain function, and recovery. You'll hear how NAD levels drop as we age, how alcohol and medications can drain it faster, and the different ways the body makes NAD on its own.Dr. Anderson also talks about today's options, from supplements like NMN, NR, and niacinamide to IV therapy. He shares when IVs make sense, when oral forms might be enough, and what to know about side effects and safety, including the common question about NAD and cancer.This is a straight talk about NAD, what's real and what's hype, and how it can support energy, recovery, and long-term wellness.

Momentum Shake with Michael Tecku – The Longevity Nutrition Formula Looking for a complete longevity shake that delivers clinically dosed ingredients for energy, focus, muscle recovery, and gut health—all in one? In this episode, Debbie talks with Michael Tecku, creator of Momentum Shake, to uncover the science and sourcing behind this all-in-one formula. Learn how it combines 30 g grass-fed Irish whey protein, collagen, colostrum, NMN for NAD⁺, lion's mane, methylated B vitamins, electrolytes, L-glutamine, and hyaluronic acid at research-backed doses for true cellular support.

In this episode of Accelerated Health with Sara Banta, I talk about one of the hottest topics in the biohacking and longevity world: NAD Supplements — Miracle Molecule or Metabolic Trap?If you've tuned into a biohacking podcast, stepped into an IV clinic, or scrolled through a longevity forum, you've likely heard the hype around NAD+. It's being called the cellular currency of youth—linked to mitochondrial power, anti-aging benefits, brain health, and even lifespan extension.But here's the truth no one's talking about: NAD+ isn't always safe. I talk about how NAD+ could be harmful if your metabolic terrain is compromised by histamine intolerance, methylation issues, sulfur sensitivity, spike protein exposure, or even hidden cancer.Before you book your next NAD+ infusion or stock up on NMN supplements, watch this episode first.Supplements Featured In This Episode:• Acceleradine® Iodine https://www.acceleratedhealthproducts.com/products/acceleradine-iodine-supplement • Accelerated Liver Care™ https://www.acceleratedhealthproducts.com/products/accelerated-liver-care • Accelerated C60™: https://www.acceleratedhealthproducts.com/products/accelerated-c60 • Accelerated Methylene Blue® https://www.acceleratedhealthproducts.com/products/accelerated-methylene-blue-supplement • Accelerated AMINOS™ https://www.acceleratedhealthproducts.com/products/accelerated-aminos • Accelerated Cogniblast® https://www.acceleratedhealthproducts.com/products/cogniblast-nootropic Not sure what food to eat and avoid? This guide is for you.⬇️

✨ Länger leben, besser aussehen❓In dieser Folge sprechen wir über Longevity-Supplements. Welche Wirkstoffe versprechen nicht nur ein längeres, sondern auch ein gesünderes Leben?

Apologies there was a glitch in the recording system, please enjoy the last hour (8a-9a) of NMN | aired on Monday, September 22nd, 2025 on Nashville's Morning News with Dan Mandis.See omnystudio.com/listener for privacy information.

Today, I'm joined by Annette Verpillot, the visionary founder of Posture Pro, whose work is transforming how we think about alignment, movement, and brain health. Annette shares her groundbreaking brain-first approach to posture, revealing how the real root of tension, pain, and subpar movement lies not just in your muscles or bones, but deep within your nervous system. Episode Timestamps: The three sensory pillars: feet, eyes, and jaw ... 00:11:11 Parkinson's, basal ganglia, and movement improvement ... 00:09:12 How sensory input drives posture, energy, and cognition ... 00:14:46 Vagal system, childhood development, and stress ... 00:17:09 Jaw and tongue posture in child and adult health ... 00:23:22 Jaw, feet, and eye interplay: posture chain explained ... 00:28:47 Risks of dental interventions without holistic assessment ... 00:32:42 Therapeutic insoles vs. orthotics and how they work ... 00:46:08 User experience: insoles, Vivobarefoot, and performance gains ... 00:51:27 Blood pressure normalization and cardiovascular connection ... 00:55:17 Hormones, HRV, and the stress cascade ... 00:59:47 Functional Activator and jaw retraining benefits ... 01:06:11 Mouth breathing, sleep, and natural jaw development ... 01:09:00 Troubleshooting, compliance, and optimizing results ... 01:14:08 Rapid-fire: myths, habits, and overhyped tools ... 01:18:22   Our Amazing Sponsors: Puori: It's minimally processed, made from pasture-raised cows' milk, and it's tested for over 200 contaminants every single batch. Go to Puori.com/NAT and use code NAT for 20% off— it also applies to subscriptions so you'll get nearly a third off the price.   Digestive Bitters by Just Thrive - One capsule before eating helps your body absorb more nutrients, ease digestion, and leave you feeling light instead of weighed down. Head over to Justthrivehealth.com/discount/NAT and use code NAT20 for 20% off.   Wizard Sciences - NMN+G Rx - A scientifically formulated blend of NMN, ginsenosides from Panax ginseng, and apigenin. Together, they enhance mitochondrial function, boost NAD+ levels, and support cellular repair. Go to wizardsciences.com and look for NMN+G. Use code NAT15 at checkout to get 15% off your purchase.   Nat's Links:  YouTube Channel Join My Membership Community Sign up for My Newsletter  Instagram  Facebook Group

NAD (Nicotinamide Adenine Dinucleotide) is vital for energy production in every cell. But did you know your body can make NAD naturally from NMN (Nicotinamide Mononucleotide), which itself comes from vitamin B3 in your diet?In this episode, Dr. Terence Tan breaks down the science behind NAD and NMN, explains whether supplements are truly necessary, and uncovers if they really deliver anti-ageing or health benefits for everyday individuals.#NMN #NAD #VitaminB3 #AntiAgeing #SupplementsFor more tips on body management, follow Halley Body Slimming Clinic on:•Facebook•Instagram•YouTubeLearn more from the doctors at Halley Body Slimming Clinic! Schedule your appointment with them:Tel: +65 6246 8806Email: askhalleybody@halley.com.sgWhatsApp: +65 8879 4938Address: 277 Orchard Road #03-16 orchardgateway Singapore 238858

What if your collagen cream isn't working, because your skin doesn't have the raw materials to use it?In this episode of Biohacking Beauty we reveal the missing half of most people's skincare: the internal protocol. From vitamin C as a collagen cofactor (“10x harder for your skin to build collagen without it”) to the role of omega-3s in plumping skin from the inside out, this episode lays out a step-by-step supplement strategy for real skin longevity.We break down why oral hyaluronic acid outperforms topical forms in clinical trials, why senescent cells are not the root cause of aging (just a symptom), and how bioactives like NMN, ergothioneine, and astaxanthin actually get expressed in the skin, unlike most topicals.We also discuss trends like matcha and how it outperforms coffee for skin health, and why oral senolytics like fisetin help eliminate zombie cells that drive inflammation and visible aging.You don't want to miss this one! What's Discussed:(00:39) Why Supplements Matter More Than Serums(03:38) The Foundational Skin Stack: C, D, E, Omegas, Collagen, HA(19:04) Mid-Tier Bioactives: CoQ10, Curcumin, EGCG, Astaxanthin(34:33) Advanced Longevity: NMN, Fisetin, Spermidine, Sulforaphane(43:05) Metabolomics Testing + Personalized Skin Protocols(52:46) Final Takeaways: Building a Skin Longevity RegimenFind more from Young Goose:The YouTH Firming Body Cream: Smoother arms, firmer thighs, tighter skin, powered by NAD+ and spermidine. Your body's anti-aging breakthrough →younggoose.com/bodycreamSpermidine Serums: Fewer wrinkles. More collagen. Real skin renewal at the cellular level. The serum your face has been waiting for →https://www.younggoose.com/collections/serumsUse code PODCAST10 to get 10% off your first purchase, and if you're a returning customer use the code PODCAST5 to get 5% off at https://www.younggoose.com/ Instagram: @young_goose_skincare

Metformin | rapamycin | ivermectin | NMN | NAD | resveratrol | spermidine

Today, I'm sitting down with the brilliant Dr. Joy Kong, a trailblazing clinician and scientist at the forefront of regenerative medicine and stem cell therapy. In this episode, Dr. Kong shares how she blends rigorous science with hands-on clinical practice to help people tackle everything from brain injuries and autoimmune conditions to skin aging and joint pain—often with transformative results.   Products she mentions: CharaOmni facial cream   Episode Timestamps: How stem cells address chronic illness ... 00:07:12 When to use IV vs. local stem cells ... 00:10:06 Types and sources: autologous, umbilical, MSCs ... 00:11:40 Why younger stem cells are superior ... 00:17:38 Emerging cell therapies: V-cells, Muse cells ... 00:20:25 Decline of stem cells with age ... 00:24:19 Stem cell therapy for neurological, organ, and autoimmune conditions ... 00:27:14 Techniques to target brain and optimize therapy ... 00:29:46 Donor screening and safety ... 00:34:41 Stem cells in healing injuries and recovery ... 00:42:28 Immune modulation and overall rejuvenation ... 00:44:56 Anti-aging protocols: frequency of IV therapy ... 00:48:36 Aesthetic uses: skin, microneedling, hair ... 00:50:08 Handling and potency of exosomes ... 00:55:01 Future of anti-aging and stem cell therapy ... 00:59:02 Legality and access in the US ... 01:03:13   Our Amazing Sponsors: Wizard Sciences - NMN+G Rx: A scientifically formulated blend of NMN, ginsenosides from Panax ginseng, and apigenin. Together, they enhance mitochondrial function, boost NAD+ levels, and support cellular repair. Go to wizardsciences.com and look for NMN+G. Use code NAT15 at checkout to get 15% off your purchase.   Ultimate GI Repair by LVLUP Health - Whether you're struggling with digestive discomfort or want to strengthen your gut health, Ultimate GI Repair provides the comprehensive support your body needs to restore balance. The ingredients are unmatched! Visit https://lvluphealth.com/ and use code NAT at checkout for 20 % off.   Body Cream by Young Goose - Powered by NAD+ APEX, CelVio Spermidine, and targeted peptides, this advanced formula restores cellular energy, supports collagen production, and enhances skin resilience. It clears cellular waste, improves skin texture, and deeply hydrates areas where aging shows most—like arms, legs, neck, and décolleté. Visit YoungGoose.com—use code NAT10 to get started, or 5NAT if you're an existing customer.   Nat's Links:  YouTube Channel Join My Membership Community Sign up for My Newsletter  Instagram  Facebook Group

Is NAD really the fountain of youth, or just another overhyped supplement trend? From energy boosts to wrinkle reduction, the excitement is everywhere, but the truth is a lot more complex. In this episode, I sit down with biomedical engineer Courtney Van Bussum to cut through the noise. Courtney brings deep expertise in cellular and longevity science,, giving her a unique perspective on both the research and the real-world clinical applications. We cover: What NAD actually is and why it's essential for energy, longevity, and healthy aging. How to know if your NAD levels are low and whether it even matters. The biggest myths and misconceptions about NAD supplements. NAD changes in pre- versus post-menopause. Why precursors like NR and NMN may backfire if deeper pathways aren't addressed. Free and low-cost ways to preserve and recycle NAD naturally. What you need to know about the molecule 1-MNA (and why it may be more important than NAD itself). Courtney Van Bussum is the COO and co-founder of Longevity Launch Labs, an innovation incubator accelerating breakthrough products and companies in cellular and longevity medicine. With a background in biomedical engineering and early experience as a strategy consultant working with both Fortune 500s and startups, Courtney brings a rare blend of scientific insight and operational execution. Before launching Longevity Launch Labs, she helped modernize operations at the Boulder Longevity Institute—one of the country's leading functional and regenerative medicine clinics. Courtney's mission is to help build parallel systems that make healthcare smarter, more proactive, and more personal—especially in the rapidly evolving world of cellular health. PAST EPISODES ON NAD THE PROBLEM WITH NAD PRECURSORS: https://podcasts.apple.com/us/podcast/88-women-in-menopause-fighting-fatigue-the-problem/id1531105768?i=1000562648714 A MORE EFFECTIVE WAY TO BOOST NAD: https://podcasts.apple.com/us/podcast/the-problem-with-nad-boosters-a-more-effective/id1531105768?i=1000523483729 WHY NR IS DANGEROUS: https://podcasts.apple.com/us/podcast/120-mitochondria-101-why-nr-is-dangerous-how-to-optimize/id1531105768?i=1000586943234 NAD 101: https://podcasts.apple.com/us/podcast/nad-101-nmn-vs-nr-the-best-and-cheapest-way-to/id1531105768?i=1000700598071   1MNA: https://1mna.com ZORA for 20% off first purchase of 1-MNA https://ohphealth.com/products/endoteliol-1mna Contact Courtney Van Bussum: Website: https://longevitylaunch.com/about-us Instagram: @cvanbuss Linkedin: https://www.linkedin.com/in/courtneyvanbussum/   Give thanks to our sponsors: Try Vitali skincare. 20% off with code ZORA here https://vitaliskincare.com Get Primeadine spermidine by Oxford Healthspan. 15% discount with code ZORA ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠. http://oxfordhealthspan.com/discount/ZORA Get Mitopure Urolithin A by Timeline. 20% discount with code ZORA at https://timeline.com/zora Try Suji to improve muscle 10% off with code ZORA at TrySuji.com https://trysuji.com Try OneSkin skincare with code ZORA for 15% off https://oneskin.pxf.io/c/3974954/2885171/31050 Join ⁠⁠⁠Biohacking Menopause⁠⁠⁠ before October 1, 2025 to win FLEXBEAM red light therapy device. Or save 10% with code ZORA at recharge.health https://recharge.health/product/the-flexbeam?ref=51   Join the Hack My Age community on: YouTube: https://youtube.com/@hackmyage Facebook Page: ⁠⁠⁠⁠⁠@⁠Hack My Age⁠     Facebook Group: ⁠⁠⁠⁠⁠⁠@⁠Biohacking Menopause⁠⁠⁠⁠⁠⁠ ⁠  Private Women's Only Support Group: https://hackmyage.com/biohacking-menopause-membership/ Instagram: ⁠⁠⁠⁠⁠@⁠HackMyAge⁠    Website: ⁠⁠⁠⁠⁠⁠HackMyAge.com⁠   

Liz is answering your questions on overdoing healthy fats, strategies for hip pain, migraine management, NMN and the links between intermittent fasting and hair loss.In this episode, Liz chats through Emma's question on overdoing healthy fats and supporting bile flow, and answers Denise's questions on hip pain and managing migraines.Liz also chats through NMN and NAD+ for Carol-Anne, plus looks at whether intermittent fasting can cause hair loss.Links mentioned in the episode:Napiers Best British BittersThe Naked Pharmacy Natruflex Turmeric - save 20% with LIZLOVESWild Nutrition Food-Grown Organic Turmaforte Turmeric - save 15% with LIZLOVESCefaly migraine deviceWhy women age differently - with Dr Andrew SalzmanIs NMN safe to take? Everything you need to know about this longevity supplementYouth & Earth NMN - save 20% with LIZLOVESA Better Second Half by Liz EarleHave a question for Liz? Send a WhatsApp message or voicenote to 07518 471846, or email us at podcast@lizearlewellbeing.com for the chance to be featured on the showPlease note, on some occasions, we earn revenue if you click the links and buy the products, but we never allow this to bias our coverage and always honestly review. For more information please read our Affiliate Policy. Hosted on Acast. See acast.com/privacy for more information.

You've probably heard NAD (nicotinamide adenine dinucleotide) called the “miracle molecule” for anti-aging — but how much of that is science, and how much is hype? In this video, I break down:

Today, I'm joined by Christian Drapeau, a visionary pioneer in stem cell science and the mind behind the concept of endogenous stem cell mobilization. Christian's journey takes us from his days as a neurophysiology researcher, wrestling with questions about memory and consciousness, to a life-changing pivot into plant medicine—ultimately leading to groundbreaking work with stem cell–mobilizing botanicals like blue-green algae and sea buckthorn. In our conversation, Christian explains how the body's innate repair system slows down dramatically with age, and why many of the answers we're seeking in regenerative health might actually be within our own biology. We dive into the latest science on harnessing your body's own stem cells for healing—covering everything from muscle recovery and brain support to remarkable outcomes in heart failure, Parkinson's, and beyond. If you want to learn more about STEMREGEN, visit stemregen.co/NAT15. If you want to experience stemregen for yourself - use code: NAT15 for 15% off your order.   Past episodes: Episode #93: How to Stimulate the Release of More Stem Cells in Your Body to Promote Healing Episode #232: Harnessing Your Own Stem Cells: Christian Drapeau's Unique Approach to Healing   Episode Timestamps: Christian's background: brain research to plant medicine ... 00:04:12 Discovery of AFA algae and stem cell mobilization ... 00:12:40 Demystifying stem cell decline and repair with age ... 00:18:02 Concerns about running out of stem cells addressed ... 00:25:23 Exosomes vs. stem cells & synergy explained ... 00:28:43 How to prime the body for more stem cell release ... 00:32:14 Stem regen's clinical data: how many stem cells? ... 00:37:06 Athletic & muscle recovery applications ... 00:41:09 Key case studies: heart failure and Parkinson's ... 00:51:34 Limitations of “biological age” markers ... 01:00:00 Stem cells, inflammation & autoimmunity ... 01:06:11 Synergies with regenerative medicine procedures ... 01:16:21 What Christian would research with unlimited resources ... 01:26:55 Common misunderstandings about regeneration ... 01:28:07   Our Amazing Sponsors: Puori - It's minimally processed, made from pasture-raised cows' milk, and it's tested for over 200 contaminants every single batch. Go to Puori.com/NAT and use code NAT for 20% off— it also applies to subscriptions so you'll get nearly a third off the price. Tro Zzz by Troscriptions -  Physician‑formulated and pharmaceutical-grade. Head to troscriptions.com, use NAT10, and get 10% off your first order. NMN+G Rx by Wizard Sciences - A scientifically formulated blend of NMN, ginsenosides from Panax ginseng, and apigenin. Together, they enhance mitochondrial function, boost NAD+ levels, and support cellular repair. Go to wizardsciences.com and look for NMN+G. Use code NAT15 at checkout to get 15% off your purchase.   Nat's Links:  YouTube Channel Join My Membership Community Sign up for My Newsletter  Instagram  Facebook Group  

There's a point where even the best skincare starts to feel like it's not doing enough. Serums stack up, results slow down. What no one tells you is that this might not be a product issue, it might be an energy issue. Specifically, cellular energy. NAD+.You'll learn why NAD+ declines with age, how that leads to slower healing, collagen breakdown, and pigmentation, and why traditional skincare can't keep up. We explain the science behind topical NAD+ delivery, how it compares to IVs and supplements, and why your body doesn't prioritize skin when it's low on resources.We also break down the best NAD+ precursors (NMN vs NR vs niacinamide), how to track your NAD+ status, and which ingredients actually raise NAD+ levels in skin, not just systemically. You'll discover how to combine fasting, HIIT, and smart supplementation to build an energy-optimized skincare routine that works from the inside out.Plus, we reveal the research behind NAD+ Apex™, the latest innovation from Young Goose that boosts epigenetic repair and reduces wrinkle depth by 15% in just 10 weeks.If you want your skin to keep up with your biohacking lifestyle, this episode is your protocol for recharging skin at the cellular level.What's Discussed:(00:06) When Your Skin Stops Responding—This Might Be Why(16:07) The Real Way to Raise Your NAD+ (Hint: It's Not Just Supplements)(22:01) What Happens When You Flood Your System with NAD+(37:32) Why Your NAD+ Supplement Isn't Helping Your Skin(43:52) The Skincare Ingredient Everyone's Talking About—But Most Get WrongThe YouTH Firming Body Cream: Smoother arms, firmer thighs, tighter skin, powered by NAD+ and spermidine. Your body's anti-aging breakthrough → younggoose.com/bodycreamSpermidine Serums: Fewer wrinkles. More collagen. Real skin renewal at the cellular level. The serum your face has been waiting for → https://www.younggoose.com/collections/serumsFind more from:Young GooseUse code PODCAST10 to get 10% off your first purchase, and if you're a returning customer use the code PODCAST5 to get 5% off at https://www.younggoose.com/ Instagram: @young_goose_skincare

Ready to glow like never before? In this episode of the THE WELL PODCAST, we're spilling all the tea

Learn how to slow, and even reverse, your biological age with cutting-edge science on the molecule that controls your longevity. Host Dave Asprey sits down with Dr. Leonard Guarente, an MIT PhD and one of the most respected longevity researchers in the world, to reveal how NAD+, sirtuins, and DNA methylation clocks can help you hack aging, upgrade your mitochondria, and extend your healthspan. This episode gives you the real science, proven by over 250 studies, behind supplements, nutrition, and biohacking tools that actually work for brain optimization, metabolism, and human performance. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR You'll learn why NAD+ is a master regulator of mitochondrial health, how DNA methylation clocks accurately measure biological age, and why boosting sirtuin activity improves resilience, neuroplasticity, and recovery. Dr. Guarente shares insider strategies from decades of functional medicine research, including nootropics, targeted supplements, fasting protocols, and diet adjustments from carnivore to Mediterranean that can shift your metabolism toward longevity. Dave and Dr. Guarente explore advanced biohacks like cold therapy, sleep optimization, and ketosis, plus how to balance these interventions with your genetics, lifestyle, and health goals. You'll also hear about the surprising role of homocysteine in brain aging, how to use lab testing to guide your longevity plan, and why resilience is the ultimate measure of health. You'll learn: • How emotional repression affects brain function, metabolism, and decision-making • Tools for nervous system regulation and emotional healing that drive high performance • Why most people fail without emotional intelligence and internal safety • How somatic awareness can optimize your energy, focus, and relationships • The science of fear, trauma release, and how to turn discomfort into growth • How to coach yourself out of stress, shame, and negative self-talk Whether you want to sharpen your brain, protect your heart, or upgrade your energy systems, this is a masterclass in smarter not harder biohacking for a longer, higher-performing life.Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday, Thursday, and Friday (audio-only) where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. Keywords: NAD+ supplementation, Sirtuin activation, DNA methylation clocks, Biological age testing, Mitochondrial biogenesis, Epigenetic reprogramming, Pterostilbene benefits, Nicotinamide riboside (NR), Nicotinamide mononucleotide (NMN), Homocysteine reduction, Oxidative stress repair, Superoxide dismutase (SOD) activation, Functional medicine longevity, Healthspan optimization, Resveratrol bioavailability, Menopause mitochondrial support, Phenylbutyrate and protein folding, High-fat diet longevity studies, Neurodegenerative disease biohacking, INCHIANTI aging study Thank you to our sponsors! Screenfit | Get your at-home eye training program for 40% off using code DAVE https://www.screenfit.com/dave. Timeline | Head to https://www.timeline.com/dave to get 10% off your first order. Zbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order. Resources: • Elysium Website. Use code ‘UPGRADE25' for 25% off the first month of a monthly subscription to any Elysium supplement: https://www.elysiumhealth.com/ • Dave Asprey's Website: https://daveasprey.com • Danger Coffee: https://dangercoffee.com/DAVE15 • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 — Introduction to NAD & Sirtuins 0:59 — Intro 7:04 — Animal vs Human Aging Studies 10:07 — Discovery of Sirtuins 14:43 — NAD's Role in Aging 15:34 — Resveratrol vs Pterostilbene 23:13 — Timing NAD Supplementation 36:34 — Diet & Lifestyle Factors 50:05 — Elysium's Basis & Signal 1:00:03 — Future Clinical Trials 1:05:14 — Psychology of Aging & Wrap-Up See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

By age 50, you've already lost half of your NAD levels—and without it, your energy, mind, and health decline faster. In this powerful episode, Dr. Kerry Gelb continues his conversation with Harvard-trained physician, NAD expert and CMO in Wonderfeel Youngr™ NMN Dr. Andrew Salzman to explore how NAD impacts blood pressure, muscle growth, VO2 max, sleep quality, heart health, and even eye diseases like glaucoma and macular degeneration. Discover how lifestyle factors like poor sleep, stress, refined carbs, and sedentary habits deplete NAD—and how exercise, diet, and smart supplementation (NMN, NR, resveratrol, hydroxytyrosol, ergothioneine) can restore it.

Today, I'm joined by the trailblazing Liz Parrish, a true pioneer in the world of longevity science and regenerative medicine. Liz doesn't just talk about cutting-edge gene therapies—she's the first patient to actually undergo many of them herself. In our conversation, Liz shares how her journey from stem cell advocacy to biotech innovation was fueled by a deeply personal mission: her son's diagnosis with type 1 diabetes.   What we discuss: How Liz Parrish got into genetics and stem cells ... 00:06:45 Transition from childhood disease to treating aging ... 00:09:35 Difference between stem cells, gene therapy, and exosomes ... 00:14:20 Challenges in gene therapy delivery and cell reprogramming ... 00:19:22 Liz Parrish as patient zero for gene therapies ... 00:22:01 Results and lessons from Parrish's self-experimentation ... 00:23:16 Senescent cells, telomeres, and aging interventions ... 00:29:22 Evolution and progress in gene therapy ... 00:34:14 Barriers and ethics of gene therapy for rare diseases and children ... 00:36:53 Public perception and future accessibility ... 00:44:55 Affordability, scaling, and redosing gene therapies ... 00:55:00 Practical longevity habits and hormones ... 01:03:54   Our Amazing Sponsors: OraltidePro™️by Profound Health - A unique mouthwash that: Promotes growth of shrinking gums, Speeds healing of mouth & tongue, Prevents oral infections (such as gingivitis), helps with enamel remineralization, reduces bacteria growth and etching and fills slots in damaged enamel. Check out OraltidePro™️at profound-health.com and use code NAT15 for 15% off your first order. NMN+G Rx by Wizard Sciences -  A scientifically formulated blend of NMN, ginsenosides from Panax ginseng, and apigenin. Together, they enhance mitochondrial function, boost NAD+ levels, and support cellular repair. Go to wizardsciences.com and look for NMN+G. Use code NAT15 at checkout to get 15% off your purchase. Fresh-Pressed Olive Oil Club: Get a full-size $39 bottle of one of the world's finest artisanal olive oils — fresh from the new harvest—for just $1. No commitment to buy anything, now or ever. Go to GetFreshLongevity.com for a free bottle and pay just $1.   More from Nat:  YouTube Channel Join My Membership Community Sign up for My Newsletter  Instagram  Facebook Group

A new study is challenging one of the most pervasive messages in health and fitness: the belief that 10,000 daily steps are needed to prolong life and prevent disease. Led by Professor Melody Ding at the University of Sydney and published in The Lancet, the study is the largest of its kind, analyzing data from more than 30 studies worldwide. Its findings suggest that significant health benefits may be achieved with as few as 7,000 steps a day—an attainable target for many who find 10,000 steps daunting. In this interview, Professor Ding discusses the scientific basis for rethinking our daily activity goals, how the research caught global attention, and what it means for public health recommendations moving forward. Peter Bowes speaks to Professor Ding to unpack what this shift in guidance could mean for millions tracking their steps around the world. PartiQlar supplementsEnhance your wellness journey with PartiQlar supplements. No magic formulas, just pure single ingredients, like NMN, L-Glutathione, Spermidine, Resveratrol, TMG and Quercetin. Get a 15% discount with the code MASTERAGING15 at PartiQlarEnergyBits algae snacksA microscopic form of life that could help us age better. Use code LLAMA for a 20 percent discountDisclaimer: This post contains affiliate links. If you make a purchase, I may receive a commission at no extra cost to you.Support the showThe Live Long and Master Aging (LLAMA) podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice. If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.

In the final hour of NMN, Dan is joined by Congressman Tim Burchett at the top of the hour, and Chris Hand joins later on. Sam wins the "Dadgumm(it)" over/under | aired on Monday, August 11th, 2025 on Nashville Morning News with Dan Mandis. See omnystudio.com/listener for privacy information.

How to raise NAD naturally? Nicotinamide adenine dinucleotide (NAD+) is a very important molecule that helps us make energy, repair damaged DNA, and is involved with sirtuins, protein-based enzymes that play a role in aging. We appear to make less NAD as we grow older. Replenishing NAD via supplements like NMN and nicotinamide riboside is a popular anti-aging strategy, and I give my thoughts on what supplements would be the best options. Let's discuss the research showing how you can raise NAD without supplements and what I believe is the very best way.    To see the research watch the video https://youtu.be/lLqWMDGey6w   Read My Rhabdo Book   Education is the best defense against getting rhabdomyolysis. I've been teaching about rhabdo for over 10 years. If you are in the US, you can order my book directly from me. ·      Purchase My Rhabdo Book ·      Order on Amazon (affiliate link)    Consultations  https://supplementclarity.com/private-consultations/    Connect With Me ·      Joe-Cannon.com ·      SupplementClarity.com ·      YouTube ·      Tiktok    About Me  For over 30 years, I've been sorting nutrition facts from fiction and helping people understand dietary supplements, using clinical research as my litmus test. I am unbiased. I analyze the research so you don't have to.   I wrote the first book about exercise-induced rhabdomyolysis. I have an MS in exercise science and a BS in biology & chemistry.    Disclaimer   Episodes are for information only. I'm NOT a medical doctor. NO medical advice is given or implied. ALWAYS consult your physician for the best health advice for you. I participate in the Amazon Associates program which means if you click on a link to amazon and make a purchase, I may make a small commission at no extra cost to you.      

The Peptique is LIVE! Go to https://thepeptique.com/ to get all your research peptides .As a loyal listener use the discount code POD15 to get 15% off the entire line of products.Have questions? Feel free to reach out to me: tarawest@westwellnessatx.comWant to get started the right way, but don't know where to start. Email me tarawest@westwellnessatx.com to set up a 30 minute $100 session to get your personalized protocol. A special discount on your first order will be included. These spots fill up fast so schedule today!Want the free peptide guide? Email me tarawest@westwellnessatx.com and comment Guide and I'll shoot it right over!Follow me on instagram @westwellnessatxTakeaways: This podcast episode marks the 50th installment, showcasing significant growth and listener engagement. The primary focus of today's discussion centers on the relationship between NAD and cancer risk. NAD is crucial for cellular functions including energy production, DNA repair, and immune response. Current research presents mixed results regarding NAD's role in cancer, demanding further investigation and caution. NAD supplementation may not inherently cause cancer but could influence existing cancer cell behavior. Listeners are encouraged to conduct their own research and consider their personal health situations regarding NAD usage. Research Links NAD+ biology, aging, immunity, DNA repairCovarrubias et al. “NAD+ metabolism and its roles in cellular processes during ageing” (review). https://pmc.ncbi.nlm.nih.gov/articles/PMC7963035/ PMCGhanem et al. “Inhibitors of NAD+ Production in Cancer Treatment” (NAMPT/NAPRT review). https://pmc.ncbi.nlm.nih.gov/articles/PMC10889166/ PMCManickam et al. “Nampt: a new therapeutic target for modulating NAD metabolism in cancer and inflammation” (2025 review). https://cdnsciencepub.com/doi/10.1139/cjpp-2024-0400 Canadian Science PublishingExtracellular metabolism and cellular uptake (do IVs reach cells?)Gasparrini et al. “Enzymology of extracellular NAD metabolism” (ectoenzymes; NR/NMN/NAM import). https://pmc.ncbi.nlm.nih.gov/articles/PMC8038981/ PMCYusri et al. “The role of NAD+ metabolism and its modulation” (2025 review; NR via ENTs; NMN dephosphorylation; SLC12A8 debate). https://www.nature.com/articles/s44324-025-00067-0 NatureYaku et al. “NR and NMN: similarities and differences” (2025 perspective; NMN→NR conversion before uptake). https://www.science.org/doi/10.1126/sciadv.adr1538 ScienceHuman IV NAD+ / IV NR dataGrant et al. “A Pilot Study… during a 6-hour intravenous infusion of NAD+” (750 mg IV NAD+, plasma/urine...

View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter's Weekly Newsletter Eric Verdin is a physician-scientist and the CEO of the Buck Institute for Research on Aging whose career has centered on understanding how epigenetics, metabolism, and the immune system influence the aging process. In this episode, Eric traces his scientific journey from studying viruses and histone deacetylases (HDACs) to leading aging research at the Buck Institute, offering insights into how aging impairs immune and nervous system function—including thymic shrinkage, chronic inflammation, and reduced vaccine response—and how these changes impact lifespan. He explores the metabolic underpinnings of aging, such as oxidative stress and insulin and IGF-1 signaling, and he discusses practical tools like zone 2 cardio, ketogenic diets, and GLP-1 drugs. The conversation also covers declining NAD levels with age, the roles of NAD-consuming enzymes such as sirtuins and CD38, and what current NAD-boosting strategies (like NMN, NR, and IV NAD) can and can't accomplish. Eric weighs in on promising longevity interventions including rapamycin, growth hormone for thymic regeneration, and anti-inflammatory therapies, while also examining the promise and limitations of current biological age tests and the potential of combining epigenetic, proteomic, and organ-specific metrics with wearables to guide personalized longevity care. We discuss: Eric's scientific journey from virology to the field of geroscience [2:45]; How dysfunction in the immune system and central nervous system can drive aging throughout the body [5:00]; The role of metabolism and oxidative stress in aging, and why antioxidant strategies have failed to deliver clear benefits [8:45]; Other aspects of metabolism linked to aging: mitochondrial efficiency, fuel utilization, and glucose-modulating drugs [16:30]; How inefficient glucose metabolism drives insulin, IGF-1 signaling, and accelerates aging [21:45]; The metabolic effects of GLP-1 agonists, and the need to move beyond crude metrics like BMI in favor of more precise assessments of metabolic health [27:00]; The case for immune health as a “fifth horseman” [36:00]; How the innate and adaptive immune systems work together to build immune memory [39:45]; Why vaccines lose effectiveness with age: shrinking of the thymus gland and diminished T-cell diversity [44:15]; Exploring growth hormone, thymic regeneration, and the role of exercise in slowing immune aging [48:45]; The challenges of identifying reliable biomarkers for immune function, and the potential of rapamycin analogs to enhance vaccine response in older adults [57:45]; How rapamycin's effects on the immune system vary dramatically by dosage and frequency [1:03:30]; The limitations of mouse models in aging research and the need for cautious interpretation of rapamycin's benefits in humans [1:08:15]; NAD, sirtuins, and aging: scientific promise amid commercial hype [1:15:45]; How CD38 drives age-related NAD decline, influences immune function, and may impact longevity [1:23:45]; How NMN and NR supplementation interact with CD38 and NAD metabolism, and potential risks like homocysteine elevation and one-carbon cycle depletion [1:31:00]; Intravenous NAD: limited evidence and serious risks [1:37:00]; Interleukin-11 (IL-11) as a new target in immune aging, the dual role of chronic inflammation in aging, and the need for better biomarkers to guide interventions [1:43:00]; Biological aging clocks: types of clocks, promise, major limitations, and future outlook [1:48:30]; The potential of proteomics-based aging clocks for detecting organ-specific decline and frailty [2:00:45]; and More. Connect With Peter on Twitter, Instagram, Facebook and YouTube

In this re-released solo episode from 2023, Dr. Mike Belkowski revisits one of the most pivotal topics in the world of mitochondrial health: methylene blue. As interest in this powerful compound continues to grow, Dr. Mike brings back an essential conversation outlining its top ten benefits — from brain function and mood to immune support to antiviral activity and beyond!   He also shares exciting updates about the future of the podcast, including a rebrand launching in August and a major expansion of the Mitochondrial Triad into the Mitochondrial Core Four. You'll also hear about BioLight's newest supplement, BioBlue Fountain of Youth, and how combining methylene blue with red light therapy can lead to powerful healing synergy.   Whether you're brand new to methylene blue or a longtime user, this episode will deepen your understanding of why this blue dye might just be the missing link in your health toolkit. If you care about energy, mood, memory, immunity — or just want to future-proof your brain — this episode is packed with insights you won't want to miss! - Key Quotes from Dr. Mike Belkowski: “Red light therapy and methylene blue on their own are powerful tools. But when you use them together, you're getting a synergistic benefit that may be unmatched in the world of mitochondrial health.”   “The more I read, the more I research, the more I realize: this compound that started as a dye might be one of the most important mitochondrial tools we have.”   “Methylene blue has been around since the 19th century. It's safe, it's effective, and the amount of research backing its antiviral, neuroprotective, and metabolic benefits is staggering.”   Key Points:   00:00 – Introduction: A Podcast Rebrand and New Direction   03:11 – Evolving the Mitochondrial Triad into the Core Four   05:17 – Why Methylene Blue Deserves a Second Look   07:15 – BioBlue: A New Mitochondrial-Enhancing Supplement   10:45 – NMN, Folic Acid, and Gold-Silver Nanoparticles Explained   11:07 – The History of Methylene Blue: From Textile Dye to Healing Tool   15:11 – Fish Tanks, Surgery, and the Safety of MB   17:57 – Malaria Cures and Forgotten Medicine   20:16 – BioBlue FOY: The Cadillac of Mitochondrial Supplements   21:38 – Methylene Blue + Red Light = Antiviral Powerhouse   22:29 – Cognitive Enhancement, Memory, and Focus Support   23:00 – Rapid Mood Shifts and Depression Relief   24:26 – Reversing Alzheimer's: A Look at the Research   29:25 – How MB Boosts Mitochondrial Energy at the Molecular Level   31:31 – Hormonal Benefits: More Energy, Less Estrogen, Higher Testosterone   32:00 – MB as an Antidote for Poisoning and Metabolic Toxins   36:29 – Methylene Blue's Powerful Antiviral Capabilities   44:12 – Alzheimer's Hallmarks Reversed with MB and Red Light Therapy   55:11 – Autism, Gut Health, and Restoring Mitochondrial Function   58:44 – The Nitric Oxide Link to Depression and Brain Fog   01:03:07 – Bipolar and Mood Stabilization Studies with MB   01:04:27 – Autism, Oxidative Stress, and Endotoxin Insights   01:13:33 – MB as a Rapid Pain Reliever for Surgery and Chronic Conditions BLUE SPECIAL THIS WEEK... SAVE 20% ON ALL BIOBLUE SUPPLEMENTS!!   Choose from our wide range of BioBlue products — four varieties of liquid BioBlue and four varieties of encapsulated BioBlue. Need help figuring out which BioBlue makes the most sense for you? Respond to this email!Discount code: BLUEPODCAST Expires Thursday, 8/7, midnight PST*Discount code is not valid with bundles or 2-, 4- or 10-packs. Must use "single" option and then increased to desired quantity.   Shop all BioBlue products by clicking here! - Dr. Mike's #1 recommendations:Water products: Water & WellnessGrounding products: Earthing.com EMF-mitigating products: Somavedic Blue light blocking glasses: Ra Optics  

As consumer wearables track everything from our heartbeats to nightly sleep cycles, a new industry has emerged—one focused on making sense of this avalanche of personal health data. In an era when prevention is prized over cure, questions abound: How accurate is the data captured on our wrists and fingers? Can these metrics truly guide us to longer, healthier lives, or are we just generating noise? For Marco Benitez, a biomedical engineer and co-founder of the health data platform Rook, the challenge isn't just about collecting the numbers but turning them into actionable insights—for both individuals and the broader healthcare world. As the medical establishment wrestles with integrating this torrent of information—and as users grapple with privacy and security—a revolution in health is quietly unfolding. Peter Bowes sat down with Benitez to discuss the promise and pitfalls of wearable data, the evolving relationship between Big Pharma and digital health, and what it will take to shift the system from sick care to prevention.___If you value our video and audio content, we would appreciate your support.Any contribution - large or small - is hugely appreciated and helps us to continue sharing insights that could help us all live longer and healthier lives. With gratitude. https://www.buzzsprout.com/87724/support PartiQlar supplementsEnhance your wellness journey with PartiQlar supplements. No magic formulas, just pure single ingredients, like NMN, L-Glutathione, Spermidine, Resveratrol, TMG and Quercetin. Get a 15% discount with the code MASTERAGING15 at PartiQlarSupport the showThe Live Long and Master Aging (LLAMA) podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice. If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.

The Silent Killer of the Mind: What You Don't Know About Alzheimer's Could Be Hurting You Already What if the path to Alzheimer's doesn't begin in your 70s—but is already unfolding in your 30s, 40s, or even earlier? In this powerful conversation with Dr. Robert Love, we expose one of the most misunderstood, underestimated health threats of our generation—Alzheimer's disease—and what you can do today to not only prevent it, but potentially reverse its early effects. I've had some of the best minds on this show, but Dr. Love stands out. He's not just brilliant—he's a world-class communicator on a mission to bring hope, tools, and clarity to one of the scariest topics out there: losing your mind. Dr. Love pulls back the curtain on the real causes of Alzheimer's—and it's not just genetics. It's inflammation. It's sugar. It's chronic stress. It's poor sleep. He explains how our modern lifestyle is sabotaging our brain health decades before symptoms appear. And here's what hit me hard: your inflammation levels at age 40 are one of the strongest predictors of your Alzheimer's risk at 70. That's not fear—that's a wake-up call. But the best part? We're not powerless. From simple lifestyle shifts to breakthrough supplements like lion's mane and curcumin, Dr. Love shows us the map to protecting the most vital organ we've got—our brain. We also dive into cutting-edge science that isn't just about prevention—it's about reversal. Dr. Love shares promising new treatments and even clinical results from his medical clinic where Alzheimer's symptoms have improved or stabilized through non-drug protocols. He gives us a first-hand account of a patient who went from disoriented and forgetful to alert, clear, and sharp—all within six months. I'm telling you, this isn't science fiction. This is the new frontier of brain health. Beyond the data and science, what really resonated with me was this: so much of what protects the brain is also what builds a better life—quality sleep, exercise, meaningful learning, low stress, good food, and strong relationships. Dr. Love reminds us that joy, curiosity, and purpose aren't just nice-to-haves—they're biological armor for your brain. And if you're young and thinking this episode doesn't apply to you? Think again. The decisions you make today will echo into the quality of your future decades. Key Takeaways: Alzheimer's starts decades before symptoms appear—your 40s matter Inflammation is one of the biggest risk factors for cognitive decline Sleep, gut health, stress, and sugar all have massive impacts on brain aging Supplements like lion's mane, curcumin, and NMN can support neurogenesis Alzheimer's symptoms can be improved or reversed with lifestyle interventions Your lifestyle is not just shaping your body—it's shaping your brain This one is a must-listen. Share it with someone you love. This information can change lives. — Max Out  

Today, I'm joined by Mike Feldstein, founder of Jaspr (get $400 off this week ONLY) and a true disruptor in the world of clean air and biohacking. If you've ever overlooked just how much the quality of your indoor air affects your sleep, your immune system, and your long-term health, prepare to have your mind changed. CLICK HERE for $400 off your NEW JASPR or use code NAT at checkout. Offer ends 8/8/25. Get my Top 5 Favorite Peptides List FREE click here to download the pdf.   What we discuss: Air scrubbers vs. purifiers ... 00:07:14 Mike's journey and Jasper origins ... 00:08:48 Indoor pollution and wildfire smoke ... 00:14:09 Health impacts from indoor air ... 00:17:16 How air scrubbers work ... 00:18:05 Real-world results and user stories ... 00:20:21 Jasper's sleep and mold studies ... 00:23:36 Wildfires, urban air, and recovery ... 00:30:13 Beyond scrubbers: plants and other tips ... 00:35:44 Microplastics and Jasper's research ... 00:45:55 Filter design and DIY alternatives ... 00:51:25 Kindling Academy & healthy school movement ... 00:56:25 Extending clean air to more schools ... 01:04:43 Jasper discount offer and wrap-up ... 01:11:21   Our Amazing Sponsors: MitoBlue - Everything in the formula is there to help you think clearer, move better, and stay resilient—mentally and physically - Methylene Blue, NMN, PQQ, Apigenin and Ginseng. Go to wizardsciences.com and look for MitoBlue. Use code NAT15 at checkout to get 15% off your purchase. CAROL Bike: With its cutting-edge, science-backed method, CAROL Bike can boost your VO2max by 12% in just 8 weeks—essentially rewinding your fitness clock by a decade. The folks at CAROL Bike are offering a 100-day FREE trial! Visit http://carolbike.pxf.io/Nat or use code NAT100 for a free 100-day trial. OraltidePro  - A unique mouthwash that: Promotes growth of shrinking gums, speeds healing of mouth & tongue, prevents oral infections (such as gingivitis), helps with enamel remineralization, reduces bacteria growth and etching and fills slots in damaged enamel. Check out OraltidePro at profound-health.com and use code NAT15 for 15% off your first order.   More from Nat:  YouTube Channel Join My Membership Community Sign up for My Newsletter  Instagram  Facebook Group

Future nutrition should be personalized, with artificial intelligence as a key driver, according to Melissa Snover, founder of Nourished, a UK-based company that makes 3D-printed gummy vitamin and supplement stacks.  She believes the current approach to supplementation and health products is outdated and poorly tailored to individual needs. Snover, registered dietitian, joined us to discuss the burgeoning field of precision nutrition. Nourished uses AI-powered algorithms to create customized nutrient gummies, based on users' lifestyle data and health goals—an approach she says offers a significant leap beyond the traditional "one size fits all" vitamin regime.  PartiQlar supplementsEnhance your wellness journey with PartiQlar supplements. No magic formulas, just pure single ingredients, like NMN, L-Glutathione, Spermidine, Resveratrol, TMG and Quercetin. Get a 15% discount with the code MASTERAGING15 at PartiQlarSupport the showThe Live Long and Master Aging (LLAMA) podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice. If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.

Have you heard any of the buzz about NAD supplements? NAD is a molecule found in nearly every cell and sits at the heart of energy production and DNA repair. Our levels of NAD though can decline with age which has led to the idea that this could be one cause of many age-related diseases, chronic inflammation and cognitive decline. Enter the idea of boosting NAD levels by supplementing with NAD itself or its precursors called NMN and NR. A surface level reading of this topic will soon bring someone across all sorts of claims about benefits including extending lifespan, improving metabolic health and many more. In this podcast episode, I explain what these NAD family of molecules are and critique the clinical evidence to see how it stacks up in front of the health claims.Links referred to in the podcastReview of effect of NR supplementation in humans https://www.science.org/doi/10.1126/sciadv.adi4862Review of NMN and NR supplementation on muscle mass and function https://pmc.ncbi.nlm.nih.gov/articles/PMC12022230Episode transcriptTo access the full episode transcript, go to the following link and select the individual podcast episode and then click on the ‘Transcript' tab https://thinkingnutrition.buzzsprout.comConnect with meInstagram doctimcroweFacebook Thinking NutritionX CroweTim

Send us a textDr. Bobby unpacks the surge of health hype—from red light therapy to NAD⁺ boosters—and empowers listeners to stay curious yet skeptical using science-backed tools and critical thinking.Are claims like “boost your mitochondria” or “natural detox” real breakthroughs—or today's version of snake oil? Dr. Bobby explores why health hype is everywhere, why we're vulnerable to it, and how to sift compelling theories from proven treatments. He outlines examples of widely accepted beliefs that ultimately didn't hold up to rigorous scrutiny. Inserting stents to open clogged arteries seemed sensible, but studies like the COURAGE and ORBITA trials found no added benefit over medical management (NEJM). Dr. Bobby then turns to newer fads. Claims around NAD⁺ boosters (like NMN or NR), red light therapy, PRP for knee pain, and hydrogen water often rely on plausible-sounding mechanisms or mouse studies—but currently lack human RCTs to back them up. While these ideas may sound promising, human trials are either missing or preliminary.Why does this hype persist? Financial incentives are everywhere: the U.S. spends over $5 trillion annually on health, and the supplement market alone is worth $150 billion. Influencers, professionals, and even well-meaning providers may promote approaches they financially benefit from. As patients, we're often eager for solutions to symptoms like fatigue or anxiety—especially when conventional medicine doesn't have a satisfying answer. This opens the door for pseudoscience, placebo effects, and the viral spread of misinformation.To navigate this environment, Dr. Bobby outlines seven action steps. First, demand human evidence: ask if a treatment has been tested in RCTs, replicated, and proven in diverse populations. He recommends Examine.com for non-biased supplement research and revisiting his episode on evaluating health headlines (#22). Second, follow the money—financial conflicts should raise your skepticism. Third, be alert to hypey language like “miracle cure” or “doctor secrets”—phrases designed to manipulate, not inform. Fourth, understand the placebo effect, especially with vague symptoms. Fifth, ask  questions: “Compared to what?” “In whom?” “For how long?” “With what risks?” These shift the focus from excitement to real evaluation. Sixth, adopt what Dr. Bobby calls the mindset of a curious skeptic—open to ideas, but insistent on evidence. Finally, he urges listeners to consult evidence-literate doctors who will explore with you, both mainstream and emerging treatments with a critical eye—see episode #20 for more on choosing the right provider.Takeaways: Ask, “Has this been tested in people?” before jumping on a health trend. Beware buzzwords and financial conflicts—science, not sales, should guide your decisions. Embrace curiosity, but anchor it in real-world evidence to truly live long and well.

現代人越來越重視外表管理，尤其是「凍齡」與「美顏」成為熱門關鍵字， 其中NMN就是近年紅透半邊天的熱門討論之一， 但是你真的了解它是怎麼運作的嗎？ 台大藥學博士譚誠明從專業角度來幫大家講解什麼是NMN、為何被視為延緩老化的新希望，還有目前市面的NMN產品在標示上有什麼問題，理解抗老背後的科學原理．．． / 營養師輕食 重磅升級！【NMN力線體】 https://tw01.co/XX1wq 全台唯一！食物型態純300mg的NMN，直達文獻的有效劑量！ ✔️反式白藜蘆醇 150mg：提升NAD+ 160% ✔️還原型Q10 30mg：直接作用，能量滿滿 ✔️神秘PQQ：食物型PQQ，青春開外掛，但市場幾乎沒在賣 ✔️B-聚葡萄糖 250mg：百搭打底，調整機能 人生實用商學院 獨家 NMN力線體2入，就送膠原蛋白正貨1盒（價值$1980） 偷偷告訴你，還能搭配官網滿額贈喔！ 馬上去買→ https://tw01.co/XX1wq 專屬優惠只到7/29 的23:59，售完為止 （譚博士提到的商品請到上方網站購買與《人生實用商學院》以及吳淡如FB的的小編無關

Today, Dr. Lovely welcomes a conversation with Amitay Eshel, co-founder and CEO of Young Goose and host of the Biohacking Beauty podcast. Amitay, an entrepreneur in the biohacking and beauty industries, explains the science behind accelerated skin aging during perimenopause and menopause, focusing on how declining estrogen impacts essential skin components like collagen, elasticity, hyaluronic acid, and cellular autophagy.   Highlights from our chat: NAD+ is a foundational molecule for cellular repair and longevity, whose levels decline rapidly with age and are further reduced by falling estrogen, leaving skin "starved". Amitay focuses on an "upstream" method of anti aging with the skin, providing NAD+ precursors like NMN to replenish energy and repair functions, rather than just treating visible wrinkles. Spermadine is introduced as a "magical molecule" essential for triggering autophagy, the body's vital cellular recycling process that renews older cells and boosts collagen production. Women experience accelerated skin aging during perimenopause and menopause due to significant drops in estrogen, leading to rapid declines in collagen, elasticity, hyaluronic acid, and autophagy, contributing to a pro-inflammatory skin state. Young Goose integrates these NAD+ innovations and spermadine into its skincare range, offering a holistic approach to biological aging in the skin. Find out more about Young Goose skincare and Amitay by visiting younggoose.com (code LOVELY for a 10% discount).  Find the 2 products Dr. Lovely speaks about in the show here:  Hyperbaric Mask and the Eye C.A.R.E.  (don't forget to use the code LOVELY) !!

While most people regularly check their blood pressure or glucose, few consider routinely assessing their body's ability to move—and yet, this may be just as crucial to long-term health. Andrew Menter, CEO of Physmodo, joined Peter Bowes to explore the software company's mission to raise the profile of movement as a vital sign of good health. Andrew shares his personal journey from a career in law and finance to entrepreneurship in movement science, motivated in part by his athletic pursuits and the injuries that accompanied them. He discusses Physmodo's innovative use of computer vision technology, enabling self-assessment of mobility and posture via simple smartphone or tablet tools—making this once-specialized information accessible to everyone, not just elite athletes. He highlights the power of early intervention, the surprising ways movement influences sleep and mental health, and the growing importance of personalized preventive care.  PartiQlar supplementsEnhance your wellness journey with PartiQlar supplements. No magic formulas, just pure single ingredients, like NMN, L-Glutathione, Spermidine, Resveratrol, TMG and Quercetin. Get a 15% discount with the code MASTERAGING15 at PartiQlarSupport the showThe Live Long and Master Aging (LLAMA) podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice. If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.

Today, I'm joined by the brilliant Dr. Vincent Pedre, one of the most sought-after experts in functional medicine and an incredible advocate for what he calls “gut-centric medicine.” Together, we explore how your emotions and beliefs directly impact your gut, why there is no one-size-fits-all approach to gut healing, and the practical steps you can take to support your body's natural balance.   What we discuss: Dr. Pedre's personal and medical background ... 00:06:05 Mind-body connection and overcoming fear through meditation ... 00:09:16 Impact of antibiotics and gut health journey ... 00:18:06 Energy healing, boundaries, and the empath-practitioner challenge ... 00:21:05 Gut-brain connection and integrating mindset in healing ... 00:24:45 Mindset, mantras, and patient transformation ... 00:30:04 Personalizing gut protocols and addressing resistance ... 00:39:03 Tools: intuitive eating, true cravings vs. microbiome-driven urges ... 00:47:45 No one-size-fits-all: diversity and personalized gut diets ... 00:54:08 How the Gut Smart Protocol tailors recommendations ... 00:58:54 Probiotics, spore-based options, and gut support basics ... 01:02:48 Coffee as a gut health microhabit (toxins, plastics, quality) ... 01:06:33 Happy Gut Coffee: rationale, tips, and final takeaways ... 01:09:11   Our Amazing Sponsors: StemRegen - A plant-based supplement protocol designed to enhance stem cell function. support your recovery, flexibility, and long-term vitality. Visit stemregen.co/NAT15 and use code: NAT15 for 15% off your order. Mitolux NEW Second Generation - This second-generation red and near-infrared light therapy panel hits all the marks. Two new wavelengths—810nm and 940nm—target brain performance, deep muscle recovery, and circulation. I use GAMA mode for focus, and Fireplace 2 to wind down. Get a Mitolux BTS2 Sunlamp for 10% off at https://mitolux.com/NAT10, NAT10 will be automatically applied at checkout. MitoBlue - Everything in the formula is there to help you think clearer, move better, and stay resilient—mentally and physically - Methylene Blue, NMN, PQQ, Apigenin and Ginseng. Go to wizardsciences.com and look for MitoBlue. Use code NAT15 at checkout to get 15% off your purchase.   More from Nat:  YouTube Channel Join My Membership Community Sign up for My Newsletter  Instagram  Facebook Group

What if your skincare routine could do more than hydrate and smooth?What if it could actually reprogram how your skin ages?In this episode we break down exactly how to build a science-backed skin longevity routine—from the biology of skin aging to the ingredients and protocols that work at the cellular level. Whether you're dealing with hyperpigmentation, acne, rosacea, or just want to slow down visible aging, this episode teaches you how to treat your skin like the intelligent, adaptable organ it is.You'll learn why NMN, NR, and spermidine are game-changers in topical skincare, how to layer serums correctly, and what most routines are missing when it comes to barrier support, photoprotection, and post-procedure recovery. We also talk about the exact Young Goose products we recommend for different skin concerns—and why it's time to start choosing skincare like you choose your supplements: based on mechanism, not marketing.➡️ If you're ready to move beyond trends and build a routine that actually enhances skin health, repair, and resilience, this one's for you.We Also Discuss:01:30 – The real reason your skin ages: inside the 12 hallmarks of aging02:21 – Why NMN, NR, and spermidine changed the skincare game05:46 – The exact routine Anastasia recommends (even for sensitive or aging skin)12:00 – What to add for hyperpigmentation, acne, or rosacea24:39 – A skincare product that mimics hyperbaric chamber therapy?!Learn more about:Young GooseUse code PODCAST10 to get 10% off your first purchase, and if you're a returning customer use the code PODCAST5 to get 5% off at https://www.younggoose.com/ Instagram: @young_goose_skincareInstagram: @maratvna

Longevity Supplements: Do NMN and NR Actually Work? Read on to find out what the research says. Overview:In this week's episode, we dive into the popular supplements NMN and NR that are touted to increase longevity and healthspan. We break down what these supplements actually are, what the research says about their effects on muscle and physical function, and whether you should spend your money on them. Key Takeaways: 0:45 - What are NMN and NR? Precursors to NAD+, which declines with age 2:30 - Animal studies show benefits, but what about humans?3:45 - Results of a systematic review of RCTs in older adults on muscle strength and physical function 5:00 - Studies sponsored by industry show benefits, but lower quality evidence6:30 - Are they worth spending your money on? CTA: Dive into the research and decide for yourself - listen to the full episode now!See omnystudio.com/listener for privacy information.

一、NMN 簡介與理論基礎：* NMN (Nicotinamide Mononucleotide) 是一種備受關注的營養補充劑，尤其在健康、生物駭客（Biohacking）和抗衰老領域中廣泛討論。NMN 被宣傳為能「逆轉衰老」的「神」級補充劑。* 其作用原理與 NAD+ (Nicotinamide Adenine Dinucleotide) 分子有關，NAD+ 自 1970 年代起被研究，牽涉細胞內超過 100 個機制，其中多項與衰老相關，例如粒線體功能（細胞的發電廠）和基因修復。* NAD+ 是細胞運作的「主角」，而 NMN 則是 NAD+ 的「前驅物」（precursor），作為載體幫助 NAD+ 進入細胞發揮功效。二、研究進展與結果：* 老鼠實驗（2013-2019）：* NMN 的廣泛知名度始於 2013 年哈佛大學抗衰老專家 David Sinclair 博士發表的關於 NMN 的老鼠實驗。實驗顯示，NMN 在老鼠身上能在數天內顯著恢復粒線體功能，使其功能如同年輕粒線體。後續老鼠實驗也發現，NMN 能改善肌肉功能、新陳代謝、膽固醇和血糖等指標，使其數字「年輕化」；這些老鼠實驗的成效「令人意外地好」。* 人類實驗（2019年至今）：* 自 2019 年起，約有 18 個關於 NMN 的人類實驗，但數量「非常少」。* 正面結果： 人類服用 NMN 後，血液中的 NAD+ 含量確實會增加。* 令人失望的結果： 大部分人類研究顯示，對於大眾關心的健康指標（markers），NMN「沒有分別」，即未見顯著改善。* 零星的「曙光」： 只有在非常個別的實驗中，針對年齡超過 60 歲、肥胖且生活方式極不健康的人群，NMN 似乎有輕微改善部分數字，但這些改善「都不是真的那麼令人驚喜的」。* 整體而言，老鼠實驗令人興奮，而人類實驗結果則「令人失望」。三、關於 NMN 的討論與建議：* 主持人自身的選擇： 自從人類實驗結果顯示 NMN 效益有限後，主持人已停止服用 NMN。* 人類實驗數據的局限性： 目前人類實驗的數量極其有限，且多為短期研究，因此對於 NMN 的長期效益和潛在副作用知之甚少。* 副作用： 目前 NMN 的短期副作用「似乎是沒有的」。* 成本效益分析：* NMN 的價格「貴」。* 從「性價比」（Bang for Bucks）角度來看，將同樣的錢用於健身會籍或桑拿會籍，其效益證明遠高於 NMN。* 美國 FDA 近一兩年已將 NMN 從補充劑列表中移除，認為其可能不屬於補充劑範疇，因此在美國較難購買，這也可能影響其普及性和價格競爭。* 藥廠即便未來將其作為處方藥銷售，保險公司亦可能因其高價且缺乏壓倒性效益而不予承保，影響其市場普及。* 維他命 D 等普及且專利期過後的補充劑之所以便宜，是因為市場規模大且缺乏專利限制，能大規模生產，這點 NMN 尚不具備。* 健康管理的優先順序：* 補充劑在健康管理中應排在「最低」的位置。* 更重要的健康支柱包括：飲食（如控糖飲食）、睡眠、壓力管理和運動。* 改善睡眠和運動的效益遠大於服用補充劑。* 補充劑的合理使用：* 補充劑應用於「身體需要的東西」，例如經血液測試證實缺乏的維他命（如維他命 D）或礦物質（如鎂）。* 例如，許多居住在陽光不足地區的人，即使不進行血液測試，也可能推斷自己缺乏維他命 D，此時適量補充可能是合理的。* 主持人透過 DNA 檢測發現自身維他命 D 吸收存在「弱點」，因此需要比常人攝取更多來達到同樣效果。* 補充劑應是「輔助性質」或「補洞」的工具，用來彌補生活習慣或飲食結構上的不足，而非替代。例如，若難以從飲食中攝取足夠 Omega-3，魚油丸可作為補充。* 批判性思維與警惕「神藥」心態：* 健康是「累積的效果」（compound effect），而非單靠服用某種「神奇」的補劑就能「長生不老」或「逆齡」。單靠補充劑解決問題的心態非常「危險」，會導致人們忽略建立真正健康的習慣 。* 如果 NMN 真的如宣傳般「神奇」，它應該會變得「很普及」，因為「這個世界沒有什麼秘密」。所有健康行動都應有「一定的證據去支援」，這是一種「科學精神」。* 健康的真正底線是透過了解自身狀況，建立並保持「良好的健康習慣」。 This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit leesimon.substack.com/subscribe

Welcome back to the Longevity Podcast! In this episode, I have the pleasure of sitting down with James Strole, a beacon in the radical longevity space and the visionary founder behind People Unlimited and RAADfest. James shares the personal journey that led him into the world of life extension—shaped by a spiritually open-minded mother, a pivotal loss, and a lifelong desire to challenge the idea that aging is inevitable. Get 10% off your tickets to RAADfest using code: "niddam"   What we discuss: James Strole's personal journey to radical longevity ... 00:04:00 Spiritual roots and early inspiration ... 00:10:00 Transition from spiritual to scientific approaches ... 00:13:00 Launching RAADfest and the shift toward hard science ... 00:16:00 Evolution of the longevity movement over the decade ... 00:21:00 Access to longevity innovations and RAAD Clinics ... 00:22:00 Most exciting developments: gene therapy and age reversal ... 00:24:00 Daily longevity pillars: diet, movement, mindset ... 00:26:00 Mindset and embracing the possibility of immortality ... 00:35:00 Overcoming skepticism and “against nature” arguments ... 00:41:00 Societal implications of extreme longevity ... 00:44:00 Are we at the tipping point? The “era of immortality” ... 00:47:00 Advice for newcomers: join the conversation and community ... 00:50:00   Our Amazing Sponsors: NEW Timeline Gummies: Urolithin A supports muscle strength and cellular energy. It's about improving how your body functions at the source. Mitopure is the only clinically proven Urolithin A, giving you six times more than you'd get from a glass of pomegranate juice. Visit Timeline.com/nat20 and use code nat20 for 20% off your purchase. Mitoblue by Wizard Sciences - Everything in the formula is there to help you think clearer, move better, and stay resilient—mentally and physically - Methylene Blue, NMN, PQQ, Apigenin and Ginseng Go to wizardsciences.com and look for MitoBlue. Use code NAT15 at checkout to get 15% off your purchase. Mimio: A supplement that gives you all the cellular, metabolic, and longevity benefits of a prolonged fast—even on the days when you're eating normally. Visit mimiohealth.com/nat and use code NAT FOR 20% off your first single purchase or subscription order.   More from Nat:  YouTube Channel Join My Membership Community Sign up for My Newsletter  Instagram  Facebook Group

Brian Wilson joins in on NMN with Dan MandisSee omnystudio.com/listener for privacy information.

Welcome back to the Longevity Podcast! I'm your host, Nathalie Niddam—nutritionist, human potential and epigenetic coach, and I'm excited to share another solo episode with you. Today, I'm diving into a topic that really resonated with my community on Instagram: five essential habits I wish everyone in their 40s (and honestly, any age!) knew to set themselves up for better health and longevity—without spending a dime.   Resources from the episode: • Grounding – The universal anti-inflammatory remedy • Associations between bedtime eating or drinking, sleep duration and wake after sleep onset: findings from the American time use survey • Meal Timing and Anthropometric and Metabolic Outcomes • Meal Timing, Aging, and Metabolic Health • Obstructive sleep apnea and neurodegenerative diseases: A bidirectional relation • Investigation on the Effect of Oral Breathing on Cognitive Activity Using Functional Brain Imaging   What we discuss: Digestive bitters before meals: benefits and how to use ... 00:02:10 Digestive bitters: impact on digestion, absorption, and immune system ... 00:04:01 Digestive bitters: sources, supplements, and usage tips ... 00:08:17 Training your glymphatic system for brain health ... 00:09:12 Tips to support glymphatic drainage: sleep, exercise, hydration, nutrition, sleep position ... 00:10:19 Grounding: definition, science, and health impact ... 00:13:39 How to ground in urban environments; grounding sheets and tools ... 00:17:08 Eating dinner three hours before bed: why and how ... 00:19:02 Early dinner vs. skipping breakfast for metabolic health ... 00:21:36 Circadian rhythm alignment tips and jet lag hacks ... 00:24:05 Nasal breathing vs. mouth breathing: importance and intro to solutions ... 00:24:36 Mouth breathing risks, sleep apnea, and cognitive implications ... 00:26:52 Practical tools and professionals for correcting mouth breathing ... 00:29:12 Summary of the five key longevity tips ... 00:31:59   Our Amazing Sponsors: MitoBlue by Wizard Sciences - Everything in the formula is there to help you think clearer, move better, and stay resilient—mentally and physically—Methylene Blue, NMN, PQQ, Apigenin and Ginseng. Go to wizardsciences.com and look for MitoBlue. Use code NAT15 at checkout to get 15% off your purchase.   More from Nat:  YouTube Channel Join My Membership Community Sign up for My Newsletter  Instagram  Facebook Group

 In this episode, we dive into the tiny but powerful molecule called NAD+ — the fuel your cells need to create energy, repair damage, and keep you feeling young and strong. As we age, NAD+ levels drop, and that can lead to low energy, slower healing, and more health problems. But here's the exciting part: science is showing that we can boost NAD+ through smart lifestyle habits and supplements — helping improve energy, brainpower, heart health, and even slow down aging. We'll break it all down in simple terms:  ✅ What NAD+ does in your body  ✅ Why it matters for your health and aging  ✅ How to naturally boost your NAD+ levels  ✅ What new research is saying about its future If you want to unlock more energy, sharper thinking, and better long-term health, this episode is for you! Tune in and learn how to help your body thrive — from the inside out.

Today, I'm joined by Cynthia Thurlow, a remarkable nurse practitioner, podcast host, and true hormone whisperer who is on a mission to help women thrive through perimenopause and beyond.   What We Discuss: Perimenopause, menopause, and longevity connection ... 00:06:09 Hormone misunderstandings and HRT discussion ... 00:07:34 Cynthia's clinical experience and women's health ... 00:07:53 Recognizing hormonal imbalances and PCOS in young women ... 00:12:09 Autoimmunity risks and thyroid issues ... 00:19:55 Lifestyle factors: aging, processed food, and alcohol ... 00:24:02 Fasting, digestive rest, and metabolic flexibility ... 00:35:02 Practical fasting tips for different age groups ... 00:36:38 Diet flexibility and protein-forward meals ... 00:41:26 Meal timing, circadian rhythm, and satiety ... 00:56:04 Muscle loss, strength training, and optimal protein ... 01:00:36 Gut microbiome recovery and dietary diversity ... 01:06:15 Creatine: benefits, dosing, and sourcing ... 01:08:36 Where to find Cynthia and her products ... 01:15:30   Thank You To Our Sponsors: Peptide Pro App: can help manage every part of your peptide protocol. From smart scheduling to real-time dose checklists, note taking, and easy calculations. Listeners receive 50% off for the first month. Visit www.peptidepro.app to download the app and use code NATHALIE50 to get started today.  BEAM - These minerals come from humate, a natural substance formed over millions of years as freshwater plants broke down and deposited their nutrients into the soil. Over time, those minerals concentrated into this black, crystalline material that's now one of the most mineral-dense substances on earth. That's what's going into your body—and your cells absorb it within minutes. Visit https://www.beamminerals.com/NAT20 and use code NAT20 for 20% off.  Wizard Sciences - Mitoblue - Everything in the formula is there to help you think clearer, move better, and stay resilient—mentally and physically - Methylene Blue, NMN, PQQ, Apigenin and Ginseng. Go to wizardsciences.com and look for MitoBlue. Use code NAT15 at checkout to get 15% off your purchase.   Learn more from Cynthia Thurlow: Website Twitter Instagram Facebook LinkedIn  Youtube   Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter  Instagram  Facebook Group

One day, you forget where you put your keys. Next, you're walking into a room and can't remember why. And maybe the worst part? You start to wonder if this is just part of getting older.But what if it's not?In this episode, Dr. Josh Helman explains why brain fog, forgetfulness, and mental fatigue hit harder after 40 and what you can do to fight back.He's not just an MD. Dr. Josh is a Harvard-trained biochemist and emergency medicine physician who now helps people reverse Alzheimer's and reclaim their mental clarity. His message? It's not too late. And the decline isn't inevitable.We talk about why your sleep quality, not just the number of hours, quietly shapes your brain's future. We get into the sneaky role of inflammation and gut health, why environmental toxins are slowly hijacking our minds, and the powerful but often overlooked link between stress and dementia risk.And Dr. Josh doesn't stop at theory. He gives you the exact supplements he recommends (including creatine), the detox routines that actually work, and why donating blood might just save your brain.Whether you're worried about your own cognitive health or caring for a parent who's slipping, this episode is your action plan.Because aging doesn't mean losing who you are.Timestamps:00:00 - Introduction05:23 - Dr. Josh's background and journey to brain health06:30 - What is Alzheimer's, and why is it reversible?11:01 - How sleep quality impacts brain health15:54 - Exercise and its connection to brain function18:11 - Nutrition for brain health and the gut-brain connection22:17 - Stress management for cognitive performance29:53 - Environmental toxins and cognitive decline32:38 - DDT and its lingering impact on brain health35:35 - How to detoxify your brain and body41:46 - Early warning signs of cognitive decline44:14 - Dr. Josh's process for reversing Alzheimer's49:02 - The importance of reducing medications50:34 - Top brain-boosting supplements56:08 - Final thoughts on reclaiming brain health

If you've been anywhere near health optimization circles, you already know Ben Greenfield as a NYT bestselling author, former Ironman triathlete, coach, one of the OGs of biohacking. Today, he's my guest on the Longevity podcast.   What we discuss: Ben's new home, cold exposure, and microdosing cryotherapy ... 00:06 Writing, updating, and revising “Boundless” ... 00:09 Key updates: Self-quantification, longevity, new detox protocols ... 00:12 High-tech blood filtration and its impact ... 00:15 Daily detox strategies: Lymphatic movement, sauna, exercise ... 00:17 Ben's evolution: From strict keto to Mediterranean-style eating ... 00:21 Genetics, ancestry, and personalized nutrition lessons ... 00:23 Impact of endurance training, hormone and gut issues, recovery via flexible dieting ... 00:27 Addressing high coronary plaque: Statins, PCSK9 inhibitors, supplementation ... 00:35 Tracking heart health non-invasively (CIMT) ... 00:38 Thoughtful, limited use of pharmaceuticals for health ... 00:44 Peptides: Orals, protocols, favorites (BPC-157, TA1, etc.) ... 00:47 GLP-1 agonists: Powerful but require careful dosing ... 00:51 Biohacks gone wrong: Dosing mishaps and psychedelic stories ... 00:55 Ben's three core tips: Family time, naps, and prayer ... 00:58   Our Amazing Sponsors: Wizard Sciences - Mitoblue Everything in the formula is there to help you think clearer, move better, and stay resilient mentally and physically - Methylene Blue, NMN, PQQ, Apigenin and Ginseng. Go to wizardsciences.com and look for MitoBlue. Use code NAT15 at checkout to get 15% off your purchase.   Mitolux NEW Second Generation - This second-generation red and near-infrared light therapy panel hits all the marks. Two new wavelengths—810nm and 940nm—target brain performance, deep muscle recovery, and circulation. I use GAMA mode when I want to lock in focus, and Fireplace 2 when I want to wind down. Get a Mitolux BTS2 Sunlamp for 10% off at https://mitolux.com/NAT10, NAT10 will be automatically applied at checkout.   LVLUP - Neuro Re-Generate the world's first liposomal triple peptide formula, designed to support mental clarity, focus, and overall brain health. Visit www.lvluphealth.com and use code NAT for 10% off your order.   Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter  Instagram  Facebook Group

My guest is Dr. Mark Hyman, M.D., a physician and world leader in the field of functional medicine. We discuss a systems-based framework for diagnosing and treating the root causes of disease, rather than simply managing symptoms. We also cover cutting-edge health and longevity tools such as peptides, NAD/NMN, exosomes, proactive blood testing and cancer screening, as well as nutrition, supplementation, detoxification, and strategies for addressing specific diseases and health challenges. This discussion will benefit anyone seeking to improve their vitality or combat specific health concerns. Read the episode show notes at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman Joovv: https://joovv.com/huberman Eight Sleep: https://eightsleep.com/huberman Function: https://functionhealth.com/huberman ROKA: https://roka.com/huberman Timestamps 00:00:00 Dr. Mark Hyman 00:01:48 Functional Medicine, Chronic Fatigue Syndrome, Mercury; Systems Medicine 00:08:51 Metabolic Psychiatry; Medicine, Creating Health vs Treating Disease 00:12:19 Sponsors: Joovv & Eight Sleep 00:15:06 Wholistic View of Body, Root Causes 00:19:48 Medicine & Research; “Exposome”, Impediments & Ingredients for Health, Whole Foods 00:26:30 Seed Oils, Starch & Sugar, Ultra-Processed Foods; Obesity Rise 00:36:27 Sponsors: Function & ROKA 00:40:05 Tool: Ingredients for Health, Personalization; Multimodal Approach 00:46:25 Essential Supplements, Omega-3s, Vitamin D3, Multivitamin, Iodine, Methylated B12 00:56:54 Supplements & Traditional Medicine; Limited Budget & Nutrition 01:02:54 Air, Tool: Air Filters; Tap Water Filter; Tool: Health, Expense & Whole Foods 01:09:03 Food Industrialization, Processed Foods 01:14:23 Sponsor: AG1 01:16:18 Declining American Health & Nutrition, Politics, MAHA 01:26:03 Toxins, Food Additives, Generally Recognized As Safe (GRAS) 01:29:25 SNAP Program & Soda, Food Industry & Lobbying 01:36:58 Big Food, Company Consolidation, Nutrition Labels 01:44:21 GLP-1 Agonists, Doses, Risks; Food as Medicine, Ketogenic Diet 01:51:29 Cancer, Diets & Alcohol 01:54:03 Blood Markers, ApoB, Cholesterol, Tool: Test Don't Guess, Individualization 02:02:54 Mercury; Tool: Detoxification, Sulforaphane, N-Acetylcysteine (NAC) 02:04:56 Endocrine Disrupting Chemicals, Fertility, Tool: Hormone Panels; Heavy Metals 02:11:36 Upregulate Detox Pathways, Gut Cleanse, Tools: Cilantro Juice, Fiber 02:17:08 Peptides, PT-141 (Vyleesi), BPC-157, Thymosin Alpha-1; Risks, Cycling 02:22:03 Cancer Screening, Data & Personalized Health; Alzheimer's Disease 02:30:45 Longevity Switches, NAD, NMN; Exosomes, Stem Cells 02:39:50 Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, YouTube Feedback, Protocols Book, Social Media, Neural Network Newsletter Disclaimer & Disclosures

This podcast is the first episode in a series featuring companies I am eager to explore and share with my community. Today, I am thrilled to welcome Dr. Andrew Salzman, a Harvard-trained medical doctor, pioneering scientist, and esteemed inventor. Dr. Salzman is the Chief Medical Officer at Wonderfeel, where he applies over three decades of medical innovation. His research into DNA repair with NAD-activated enzymes led the way for a groundbreaking treatment for BRCA-related breast and ovarian cancers, which he licensed to Genentech. Dr. Salzman was among the first researchers to publish papers on the gut microbiome and leaky gut syndrome in the 1980s, and he has published over 170 peer-reviewed papers and holds more than 50 patents. In our conversation today, we dive into what NAD is, its significance, why it matters, and how it impacts fertility, menopause, and sexual health. Dr. Salzman walks us through the symptoms of NAD deficiency and explains how an enzyme called CD38 can emerge when NAD levels are low, triggering inflammation and oxidative stress. We explore the difference between pharmaceutical agents and nutraceuticals, examining why oral NMN is preferable and how sleep and alcohol can influence NAD levels. We cover the risk factors for breast, ovarian, and uterine cancers, looking at what we can do to reduce them, and we also talk about Wonderfeel and how their supplements and botanicals enhance wellness for women.  This is an invaluable discussion with Dr. Salzman, so you will likely want to listen to it more than once. IN THIS EPISODE YOU WILL LEARN: How our NAD levels change as we get older The role of NAD in energy production  How oxidative stress and inflammation affect NAD levels in the ovaries Why NAD is essential for sexual health Lifestyle choices that could affect NAD levels How inflammation can increase CD 38 levels and deplete NAD Why oral administration of NMN or NR is the most practical and effective method for maintaining NAD levels How alcohol affects NAD levels and increases the risk of cancer How, with Dr. Salzman's input, Wonderfeel developed a product combining NMN with botanicals to enhance NAD levels Connect with Cynthia Thurlow   Follow on Twitter Instagram LinkedIn Check out Cynthia's website Submit your questions to support@cynthiathurlow.com Connect with Dr. Andrew Salzman On the Wonderfeel website .

What are the pros, cons, and efficacy of dihydronicotinamide riboside (reduced NR), perhaps the most potent NAD+ precursor, as well as reduced NMN, taking NAD+ directly, or making it from scratch from tryptophan?