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Sermão ministrado pelo Rev. Sílvio Bizzo com base em Efésios 1.1-2. Igreja Presbiteriana Redenção.
Sermão ministrado pelo Rev. Sílvio Bizzo com base em Atos 28.17-31. Igreja Presbiteriana Redenção.
On this episode of Ropes & Gray's podcast series, Decoding Digital Health, Christine Moundas, a health care partner and co-chair of the firm's digital health initiative, is joined by Dr. Bernardo Bizzo, a senior director at Mass General Brigham AI and assistant professor of radiology in the Department of Radiology at Mass General Hospital. Dr. Bizzo discusses his work in the field of digital health and AI, including the development and clearance of AI products by the FDA. They also explore the promising aspects of AI in health care and the challenges involved in developing and deploying AI tools.
Sermão ministrado pelo Rev. Sílvio Bizzo com base em Êxodo 22.1-15. Igreja Presbiteriana Redenção.
Sermão ministrado pelo Rev. Sílvio Bizzo com base em Êxodo 21.12-36. Igreja Presbiteriana Redenção.
Sermão ministrado pelo Rev. Sílvio Bizzo com base em Atos 21.1-26. Igreja Presbiteriana Redenção.
Sermão ministrado pelo Rev. Sílvio Bizzo com base em Atos 18.1-28. Igreja Presbiteriana Redenção.
Sermão ministrado pelo Rev. Sílvio Bizzo com base em Êxodo 20.3. Igreja Presbiteriana Redenção.
Sermão ministrado pelo Rev. Sílvio Bizzo com base em Atos 12.1-19. Igreja Presbiteriana Redenção.
Sermão ministrado pelo Rev. Sílvio Bizzo com base em Êxodo 6.14-27. Igreja Presbiteriana Redenção.
Sermão ministrado pelo Rev. Sílvio Bizzo com base em Atos 5.12-42. Igreja Presbiteriana Redenção.
Sermão ministrado pelo Rev. Sílvio Bizzo com base em Atos 4.1-22. Igreja Presbiteriana Redenção.
Sermão ministrado pelo Rev. Sílvio Bizzo com base em Atos 2.22-36. Igreja Presbiteriana Redenção.
Sermão ministrado pelo Rev. Sílvio Bizzo com base em Gênesis 49.1-33. Igreja Presbiteriana Redenção.
Sermão ministrado pelo Rev. Sílvio Bizzo com base em Atos 1.1-5. Igreja Presbiteriana Redenção.
Premier Battles champion and Preston Legend BIZZO BOND rocks up to the KSC to tell us how it is!
Sermão ministrado pelo Rev. Sílvio Bizzo com base em Gênesis 34.1-31. Igreja Presbiteriana Redenção.
Sermão ministrado pelo Rev. Sílvio Bizzo com base em Marcos 13.1-2. Igreja Presbiteriana Redenção.
Sermão ministrado pelo Rev. Sílvio Bizzo com base em Gênesis 33.1-20. Igreja Presbiteriana Redenção.
Sermão ministrado pelo Rev. Sílvio Bizzo com base em Marcos 12.38-44. Igreja Presbiteriana Redenção.
Sermão ministrado pelo Rev. Sílvio Bizzo com base em Gênesis 32.1-32. Igreja Presbiteriana Redenção.
Sermão ministrado pelo Rev. Sílvio Bizzo com base em Gênesis 25.1-26. Igreja Presbiteriana Redenção.
Sermão ministrado pelo Rev. Sílvio Bizzo com base em Gênesis 24.1-67. Igreja Presbiteriana Redenção.
Sermão ministrado pelo Rev. Sílvio Bizzo com base em Marcos 10.1-12. Igreja Presbiteriana Redenção.
Sermão ministrado pelo Rev. Sílvio Bizzo com base em Gênesis 23.1-20. Igreja Presbiteriana Redenção.
Gary Bizzo, a business startup, marketing, and branding specialist, and CEO of Bizzo Management Group, joins Tejas Mehta to discuss the importance of empathy, storytelling, and community engagement in marketing and future marketing trends.
Gary Bizzo, a business startup, marketing, and branding specialist, and CEO of Bizzo Management Group, joins Tejas Mehta to discuss the evolution of digital and influencer marketing and how to become a Social Media Rock Star.
Sermão ministrado pelo Rev. Sílvio Bizzo com base em Gênesis 19.1-29. Igreja Presbiteriana Redenção.
Sermão ministrado pelo Rev. Sílvio Bizzo com base em Marcos 8.22-30. Igreja Presbiteriana Redenção.
Sermão ministrado pelo Rev. Sílvio Bizzo com base em Gênesis 4.16–5.32. Igreja Presbiteriana Redenção.
Long Hair Linda is joined by talented musician and battle rapper Bizzo Bond to exchange their best dad jokes. For more from him, follow @BizzoBond on Twitter, Instagram, and Tik Tok Get updates on music and support his merch at bizzobond.com For tickets to see Premier Battles champ Bizzo Bond face the GOAT Tony D at The Plug, taking place at The Fiddler's Elbow in Camden on 2nd July 2022, head to premierbattles.club Like what you heard? Rate, subscribe and share with a friend please :) You can get updates on new episodes by following @PodOfMercy on Twitter and Instagram, and search ‘Talk About It Network' on YouTube for the most entertaining, authentic and wild podcasts. #PodOfMercy
Sermão ministrado pelo Rev. Sílvio Bizzo com base em Marcos 1.40-45. Igreja Presbiteriana Redenção.
Sermão ministrado pelo Rev. Sílvio Bizzo com base em Gênesis 3.1-7. Igreja Presbiteriana Redenção.
Sermão ministrado pelo Rev. Sílvio Bizzo com base em Marcos 1.29-39. Igreja Presbiteriana Redenção.
About the speaker: https://www.crunchbase.com/person/vineet-toshniwal
Sermão ministrado pelo Rev. Sílvio Bizzo com base em Gênesis 1.2-25. Igreja Presbiteriana Redenção.
Sermão ministrado pelo Rev. Sílvio Bizzo com base em Gênesis 1.1. Igreja Presbiteriana Redenção.
Sermão ministrado pelo Rev. Sílvio Bizzo com base em Salmo 139.23-24. Igreja Presbiteriana Redenção.
Long Hair Linda is joined by the super talented Bizzo Bond to answer some ‘would you rather' questions, which include ‘be the last person on earth or the only man on earth' and ‘nipple length d!ck or d!ck length nipples'. Ridiculousness ensued… of course. Follow @BizzoBond on Twitter and Instagram and check out his music and previous battles here: https://linktr.ee/bizzobond Get your tickets to All The Smoke, taking place at Brixton Jamm on 5th December 2021: https://www.tickettailor.com/events/premierbattles/590189/ Like what you heard? Rate, subscribe and share with a friend please :) You can get updates on new episodes by following @PodOfMercy on Twitter and Instagram, and search ‘Talk About It Network' on YouTube for the most entertaining, authentic and wild podcasts. #PodOfMercy
Entenda a relação entre hipertrofia, treinamento e hormônios com a participação do treinador Vitor Bizzo
Gary Bizzo is a man of many hats and talents, he is a serial entrepreneur, start up investor, university professor and consultant to innovative start up companies. On this episode he shares some examples with us on financing disruptive technologies. Gary also reinforces the thought to surround yourself with talent and be a trusting leader. Please enjoy, subscribe, and share the Build Your Success Podcast with your friends. https://buildcs.net/ brianb@buildcs.net http://www.garybizzo.com/
Check out The Boom Bap Hour Uncut's raw and uncut commentary on the hottest entertainment news! --- This episode is sponsored by · Anchor: The easiest way to make a podcast. https://anchor.fm/app --- Send in a voice message: https://anchor.fm/the-boom-bap-hour-uncut/message
Check out The Boom Bap Hour Uncut's raw and uncut commentary on the hottest entertainment news! --- This episode is sponsored by · Anchor: The easiest way to make a podcast. https://anchor.fm/app --- Send in a voice message: https://anchor.fm/the-boom-bap-hour-uncut/message
Check out The Boom Bap Hour Uncut's raw and uncut commentary on the hottest entertainment news! --- This episode is sponsored by · Anchor: The easiest way to make a podcast. https://anchor.fm/app --- Send in a voice message: https://anchor.fm/the-boom-bap-hour-uncut/message
Check out the newest Bizzo Stories, where he meets an unknown band from Philly that grew to be one of the most prolific groups in Hip-Hop history. --- This episode is sponsored by · Anchor: The easiest way to make a podcast. https://anchor.fm/app --- Send in a voice message: https://anchor.fm/the-boom-bap-hour-uncut/message
Instagram RoidzClub https://www.instagram.com/roidzclub/ Vitor Capial https://www.instagram.com/vitorcapial/ Vitor Bizzo https://www.instagram.com/vitorbizzo/
Check out the newest episode of Bizzo Studio Stories! Bizzo meets legendary DJ and Hip Hop pioneer Grandmaster Flash, where he puts Bizzo's skills to the ultimate test. --- This episode is sponsored by · Anchor: The easiest way to make a podcast. https://anchor.fm/app --- Send in a voice message: https://anchor.fm/the-boom-bap-hour-uncut/message
https://roidz.club/ Instagram MrSaizen https://www.instagram.com/mrsaizen/ Vitor Bizzo https://www.instagram.com/vitorbizzo/
https://www.engati.com/ Engati is the world's leading no-code, multi-lingual chatbot platform. Blog link: https://blog.engati.com/ | Subscribe now. Follow us on Facebook: http://s.engati.com/157 LinkedIn: http://s.engati.com/158 Twitter: http://s.engati.com/156 Instagram: https://www.instagram.com/getengati/
PeopleHum talks to Gary Bizzo on how the new age technology and artificial intelligence gives rise to automation and is a helping hand to the rising entrepreneurs. If you like the podcast, please follow the channel, so we could keep producing more content like this!
O Heavy Meta de hoje recebe Ricardo Mattana e Gabriel Bizzo, finalistas da sexta edição do CLUBE DA LUTA PAUPER para falar sobre a final secreta, o field do próximo campeonato e, claro, os dois campeonatos super importantes que rolaram no mol nesse último final de semana. Estaríamos vendo um retorno triunfante do BOROS MONARCH? Tem muito conteúdo hoje! Devolve um prisma, baixa um prisma, devolve um prisma, baixa um prisma e clica no play! Comentados no episódio HM20 sobre o Clube da Luta Pauper https://open.spotify.com/episode/6osgWuOXIDv7v0nQxow7xn?si=pwE7XjkQSg-uV2q3cM3TFg Pauper Challenge 23/02 https://magic.wizards.com/en/articles/archive/mtgo-standings/pauper-challenge-2020-02-24 Pauper Premier 22/02 https://magic.wizards.com/en/articles/archive/mtgo-standings/pauper-premier-2020-02-23 Stompy Mtg Blog: Usar ou não usar delver? https://www.youtube.com/watch?v=rPapxdVqp4A Stompy Mtg Blog: Izzet Skred Sideboard Guide https://www.youtube.com/watch?v=ux3ueRF3x_U JETHRO TULL - Songs From The Wood https://www.youtube.com/watch?v=c3Xlmh0lvK0 Shaman - Fairy Tale https://www.youtube.com/watch?v=-0SbwokIF4Y ------------------------------------------ Ricardo Mattana: Twitter Canal do Youtube Facebook Artigos na Ligamagic ------------------------------------------ Heavy Meta no youtube! Edição: Fernando Portelada (@fportelada_videos e @ifportelada no twitter) Design de marca: Felipe Teixeira (@felipetxs)
Check out Bizzo's cool story on meeting Tah Tah - Jay Z's best friend in the studio. --- This episode is sponsored by · Anchor: The easiest way to make a podcast. https://anchor.fm/app --- Send in a voice message: https://anchor.fm/the-boom-bap-hour-uncut/message
Neste primeiro podcast, os Engenheiros de Segurança do Trabalho Rogério Santos e Tatiana Coaracy levantam temas e discutem acerca da NR 10 em conjunto com o maior especialista no assunto no Brasil, Engenheiro Aguinaldo Bizzo. Bizzo relata recente participação na Feira A+A que ocorreu em DUSSELDOLF na Alemanha, trata-se de uma das maiores feiras de segurança do trabalho do mundo, ocorre a cada 2 anos, segundo o mesmo em termos de equipamentos o Brasil não deixa a desejar como muitos pensam, no geral estamos muito bem, o que muda são questões de “gestão”. Rogério segue levantando a questão da “negligência” da Análise de Risco na área de segurança com eletricidade, segundo Bizzo sem dúvida um dos temas mais importantes quando se fala de eletricidade, transcorre dizendo que a NR 10 é uma norma de gestão e responsabilidade, a qual fala da obrigatoriedade da análise de risco, porém não fala como deve ser feita... Em breve novos vídeos sobre o assunto, fique atento em nossas redes, sempre com muitas novidades no segmento de Segurança do Trabalho.
First things first, THANK YOU for helping me reach 1,000+ global plays today. I am extremely chuffed and i've announced a fan give away on the show for my audience in South Africa. Byron AKA Bizzo made his debut on my show where he discusses his displeasure with the entire LFC team being in the starting 11 of the LFC/MUFC combined team from Sky Sports pundits. Bizzo makes arguments for a few United players and we chat briefly about our expectations of Manchester United vs Liverpool at Old Trafford. As controversial as ever, enjoy this show and thank you again for helping me reach this milestone.
Please SUBSCRIBE & Leave a REVIEW! If you enjoy this podcast, checkout other content from the Sana G Morning Show: Crush On You: https://www.iheart.com/podcast/960-Sana-Gs-Crush-On-You-28823199/ Sanacast Podcast: https://www.iheart.com/podcast/139-Sana-G-Morning-Show-25095719/episodes/ Sana G Morning Show ON DEMAND Podcast: https://www.iheart.com/podcast/139-Sana-G-Morning-Show-25095719/episodes/ Blog: http://kmel.iheart.com/featured/the-sana-g-morning-show/ YouTube: https://www.youtube.com/user/KMELtv?sub_confirmation=1
Please SUBSCRIBE & Leave a REVIEW! If you enjoy this podcast, checkout other content from the Sana G Morning Show: Crush On You: https://www.iheart.com/podcast/960-Sana-Gs-Crush-On-You-28823199/ Sanacast Podcast: https://www.iheart.com/podcast/139-Sana-G-Morning-Show-25095719/episodes/ Sana G Morning Show ON DEMAND Podcast: https://www.iheart.com/podcast/139-Sana-G-Morning-Show-25095719/episodes/ Blog: http://kmel.iheart.com/featured/the-sana-g-morning-show/ YouTube: https://www.youtube.com/user/KMELtv?sub_confirmation=1
Check out Bizzo's cool story on how he came to meet Chuck D. of Public Enemy. --- This episode is sponsored by · Anchor: The easiest way to make a podcast. https://anchor.fm/app --- Send in a voice message: https://anchor.fm/the-boom-bap-hour-uncut/message
On the Dec 27th, 2017 YourLIVINGBrand.live show we interview Gary Bizzo of www.garybizzo.com. Gary is a social media rockstar and I will let him tell you why.
Visit EOFire.com for complete show notes of every Podcast episode. Gary mentored over 1000 business leaders, investors and entrepreneurs. As an Agent of Change, he used social media to change Canadian Law with Bill C470. The former Founder/COO of Kickstart Business Catalyst, he is now the CEO of Bizzo On Business, an online incubator/accelerator academy.
Imagine if you started a business and it was successful the first time around? No failure, no troubles, no problems--sounds like a dream, right?! In this episode we are talking to Gary Bizzo, entrepreneurial thought leader and mentor for over 1,000 entrepreneurs. He shares with us why and how it is the little things that can help make your business a success the FIRST TIME. Sometimes they simply just get over looked. Gary also reveals in this episode: Creating your business plan using the ESSENTIALS How guerilla marketing helped him grow his business quickly (and what guerilla marketing means!) Forming a business based on your lifestyle - not just the dollar signs Gary Bizzo made big changes in Canada, but also in his personal life. He realized that it is never too late to start something new in business but also how to pivot in your current one. Be able to adapt in every environment, sometimes things happen and it changes the course of where your business is going. Know that it is ok! Embrace the change and see where it takes you! Mentioned in this episode: Don’t forget to pick up Gary Bizzo’s book called “How To Start A Business Right the First Time” Connect with Gary: @garybizzo http://garybizzo.com Connect with Kelly: www.kellyroachcoaching.com www.facebook.com/kellyroachinternational www.twitter.com/kellyroachint A HUGE thank you for listening to Unstoppable Success Radio! I would be so grateful if you left me a rating and review! My mission and goal is to serve you, my listeners, so please submit your questions for an upcoming #ask Kelly episode by emailing coaching@kellyroachcoaching.com or @kellyroachint or calling 610 910 3600 to submit your questions! Here's how I can help you achieve your goals: -How to build, scale and automate growth in your business:kellyroachcoaching.com/yes -Take your hobby, side hustle or new business quickly to the 100k mark: kellyroachcoaching.com/100k -Turbo charge your productivity, break through overwhelm and the impact the profit in your business in 30 day or less kellyroachcoaching.com/higher-profits/ -Inquire about Private consulting and coaching by completing the application at: http://kellyroachcoaching.com/apply-now/ Get insider tips and resources only available to my private email community by texting IGNITE to 44222 or visiting kellyroachcoaching.com and selecting any of the exciting resources or trainings available for immediate download. Have you gotten your copy of UNSTOPPABLE: 9 Principles for Unlimited Success in Business and in Life at Amazon here NOW!
The How of Business - How to start, run & grow a small business.
Starting a successful small business, the first time! Gary Bizzo, an entrepreneur, mentor, and author is our guest. Gary shares his interesting and diverse background, and his experiences, tips and advice on how to start a successful business the first time. Gary believes you must have a business plan and the resources in place before you start your business, and surround yourself with good people. Henry Lopez is the host of this episode of The How of Business show – dedicated to helping you start, run and grow your small business. (TheHowOfBusiness.com)
Gary Bizzo is an accomplished business owner, mentor and social media ‘Agent of Change’. Over the years he has mentored over 900 investors, business leaders and entrepreneurs. While he was running his own advertising agency he was approached to lead a business incubator in Vancouver and did this for 10 years while also running his own business. As a top social media influencer Gary has a large following on various platforms online and he was able to help change a Canadian Law (Bill C-470) by leveraging on the power of Twitter. His specialities are startups, incubators and finance - all of which he gives us an insight to in this interview. Gary shares with us the key challenges that he sees small and micro enterprise owners making all the time and shares a unique idea on how to creatively solve these challenges through a pay-it-forward system. Doesn’t make sense? Then have a listen to the podcast! He also goes over what he has learned about the importance of confidence and value perception from working closely with and mentoring hundreds of businesses. He also shares some advice for new entrepreneurs and what led to him writing his first book titled, How to Start a Successful Business – the First Time. In an interesting story Gary shares about the time he spent with Michael Gerber, author of The E-Myth, what he learned from him and their collaboration. More about Gary can be found at the following websites and social media platforms: Website: http://www.garybizzo.com/ Facebook: Gary C. Bizzo Instagram: @mentorbizzo Twitter:@garybizzo Gary’s books, How to Start a Successful Business – the First Time, can be found on Amazon here. He will be publishing two more books in 2017 one titled, Social Media Rockstar and another titled, Startup. Gary also recommends all entrepreneurs and startup owners to read Michael Gerber’s The E-Myth. Conference highlight CAI Annual Conference and Exposition www.caionline.org Las Vegas, NV: May 3rd - May 6th 2017 SPRH Podcast is sponsored by: Knight Dik Insurance http://www.knightdik.com/ Cumulus Global www.CumulusGlobal.com
Gary Bizzo has Mentored over 1000 business leaders, investors & entrepreneurs. Bizzos book, “How to Start a Successful Business The First Time!” is on Amazon. He was a National Finalist in the 2014 Business Development Bank of Canada Mentorship Award. His book was nominated for the International 2014 Small Business Book Awards. He was a Nominee for the 2014 & 2015 International Small Business Influencer Award. Entrepreneur Magazine, in 2014, said Bizzo was one of 17 Masters of Marketing & PR Entrepreneurs Can Learn From. Bizzo is a Social Media ‘Agent of Change’ and an expert at managing multiple businesses with several hundred thousand followers on Twitter, LinkedIn and Facebook. He helped change Canadian Law through Bill C-470 that made charities more transparent. He is an Elite Weekly writer for Equities.com the largest platform for emerging growth companies. He is also a Contributing Columnist for Stockhouse.com, Canadas #1 financial portal and one of North America’s largest small cap investor communities. Bizzo ran two business incubators for 13 years where a community of entrepreneurs with innovative ideas were nurtured and supported through workshops, bootcamps, mentoring, executives in residence and financing options. He is a Partner at Equifaira Advisors Inc. – Liquidity Event Planners. Equifaira are specialists in strategy & execution, corporate finance, capital formation & investor relations. His next book, “Startups From Early Stage to Early Growth” will be in stores in May 2017. What you’ll learn about in this episode: What Gary’s been up to since his last interview on System Execution Gary’s upcoming books “Social Media Rockstar” and “Startups From Early Stage to Early Growth” How Gary successfully manages multiple businesses Gary’s recent work with Equifaira, a consulting company that works with companies that aren’t public yet to raise money The system that Equifaira has in place to be in compliance with the British Columbia Securities Commission Why Equifaira is very selective of the companies they work with Why they help the people they work with sell no more than 49% of their companies How the social media piece fits into the overall system Upcoming projects for Gary Ways to contact Gary: Website: garybizzo.com Email: ceo@garybizzo.com Twitter: @GaryBizzo LinkedIn: www.linkedin.com/in/garybizzo Book: “How to Start a Successful Business The First Time!” A transcript of this episode is available at: systemexecution.com/managing-multiple-businesses-system
Gary Bizzo has been a Mentor to over 1000 business leaders & entrepreneurs. He was a National Finalist in Canadas 2014 BDC Mentorship Award & his book “How to Start a Successful Business The First Time!” has been nominated for the International 2014 Small Business Book Awards. Entrepreneur Magazine, said Bizzo was one of 17 Masters of Marketing & PR Entrepreneurs Can Learn From. Bizzo was Founder/COO of Kickstart Business Catalyst, a business incubator/accelerator & Venture Financing business. He is currently a Partner with Equifaira Advisors, Liquidity Event Planners, specialists in strategy & execution, corporate finance, capital formation & investor relations. What you’ll learn about in this episode: Gary’s system of execution How Gary figured out that he was really good at execution and why he chose this area to excel in it Why execution all comes down to organization Gary’s 7 digital folders that are the foundation of his system of execution How Gary and his partners are changing the system to simplify the process Getting everyone to comply with this system The calendar system that Gary and his partners will be implementing next Ways to contact Gary: Website: garybizzo.com Twitter: @GaryBizzo LinkedIn: www.linkedin.com/in/garybizzo Book: “How to Start a Successful Business The First Time!”
Newcomer of the year Heretic joins Tom to discuss his winning sarcasm and rapid climb to the upper echelons of the scene. Help support BRR and pick up some exclusive merch: https://battlerapresume.bigcartel.com/ For Patreon exclusive episodes, full interviews weeks before release + tons of other BRR content, check our donation page and help out the show: https://www.patreon.com/battlerapresume Battles discussed: vs. Kid Verbal vs. Danny Jaqq vs. Bizzo vs. Stowaway vs. Innuendo vs. Shuffle T @battlerapresume // battlerapresume@gmail.com Hosted by @tomkweipoet // Help support BRR: http://www.redbubble.com/people/battl... Theme by Alex Cottrell (http://alex-cottrell.com/) Logo by https://www.behance.net/Danogormandesign Thumbnail design by Nathan Jones (https://nathersjonesblog.wordpress.com) Photo by http://www.idjphotography.com/
Gary mentored over 1000 business leaders, investors and entrepreneurs. As an Agent of Change, he used social media to change Canadian Law with Bill C470. The former Founder/COO of Kickstart Business Catalyst, he is now the CEO of Bizzo On Business, an online incubator/accelerator academy. Visit EOFire.com
In this episode of Discovering Darwin we discussed the fifth chapter of Origin of Species titled Laws of Variation. Ironically there are no laws actually discussed in the chapter but Darwin does outline a variety of phenomenon and patterns of inheritance and variation that puzzled and intrigued him. When we consider the great variation in forms that we see in nature it is often difficult to tease apart the cause of that difference in form. For example, variation in form may be genetically determined as described by Mendel and his experiments with pea plants. Of course Darwin did not have a sense of genes and how multicellular plants (excluding mosses) and animals get two copies of each gene, one form their mother and one from their father, that codes for traits. Those two copies of the genes determine the expression of physical traits. Looking at the chart below of Mendel's pea plant traits you can see how variable the sweet pea plant could be.Imagine Darwin's confusion if he saw pea plants with yellow or green seeds, purple or white flowers and variation on where the flowers are located on the plant. Even more intriguing is the notion that yellow seeded pea plants with purple flowers could be crossed and produce offspring with green colored pea seeds and white flowers! Today, with our knowledge of genetics, we understand the concept of recessive and dominant traits and how recessive traits can be hidden in the parents but expressed in the offspring when they inherit only the recessive versions of the gene.We discussed if Darwin actually was aware of Mendel's work and Josh mentioned an interesting paper by Bizzo and El-Hani that argued Darwin was aware of Mendel's work. That paper can be found here.Acclimation versus AdaptationSarah discussed how Darwin seemed to use the terms acclimation and adaptation interchangeably as he worked through his understanding of how organisms can exhibit variation in form. Today biologists see these two concepts as separate and unique characteristics.Some of the best examples of acclimation can be seen in arctic animals, like this arctic fox, that can dramatically change their coats from winter to summer. Acclimation is when the organism alters its form, physiology or behavior in response to local environmental conditions. Often these changes are induced by hormonal changes in the organism which themselves are triggered by environmental stimuli. These changes are typically not permanent.In contrast, if you look at a population of a species you may see variation in forms but these are adaptations to local conditions. An interesting example of local adaptations is seen in the north American rock pocket mouse (Chaetodipus intermedius) that lives in the southwest desert areas of US and Mexico. This small, bite sized rodent, lives in a variety of rocky habitats which differ in color depending upon the geological history. The brown sandy colored rocks are in contrast to the black balsaltic rock that formed from geologically recent lava flow events. The mice have strong local selection to avoid being seen by their natural predators so selection favors coat colors that blend with the background. The top two images are showing the local mouse in its native local condition, the bottom two panels are swapping mice from their native locations. All of these mice are the same species but their coat color variation is genetically determined by expression of Mc1r gene for black pigmentation and that gene has undergone local mutations and selection. http://uanews.org/story/coats-different-color-desert-mice-offer-new-lessons-survival-fittest We also discussed how creatures locally adapt to caves by losing the ability to see and often become pale colored or completely lose their coloration. Josh read a wonderful quote by Darwin where he described blind cave crabs possessing components of the eye but it was incomplete in form.Image from http://imgarcade.com/1/blind-cave-crabWe also discussed how Darwin recognized the pattern that certain traits correlated with individual sexes but did not understand how that was possible. Darwin spoke of calico cats and how he was puzzled that they are typically only female. Of course we now understand that sex is determined by sex chromosomes and traits can be sex-linked when they are located on the sex chromosome, which in mammals are called X and Y chromosomes (females are XX, males are XY).A very nice summary of the genetics of calico cats can be found here.image from WikipediaDuring the podcast we discussed Darwin's critique of the idea that every unique species was individually specially created by a Creator. Darwin mentioned how improbable it was that the creator would take the time to make different varieties of turnips. This discussion stimulated a flashback for Josh to remember when he was an undergraduate seeing outside a professors office a classic Farside cartoon concerning special creation. "Oh my, me...." copyright Gary LarsonModern View of Inheritance and Sources of Genetic VariationIn contrast to Darwin's semi-blending model of inheritance, biologist today rely on the particulate model of inheritance, which is based on the idea that individuals gain specific set of genetic particles (chromosomes) from both their parents. We now understand that the process of sexual reproduction creates great variation in offspring without relying solely on the process of genetic mutations to create new forms.Yes genetic mutations are important in creating new traits (see mouse story above) but much of the genetic variation we see in nature within a generation derives from shuffling and recombining preexisting traits when creating gametes (eggs and sperm) and combining those gametes (fertilization) into a new individual.To illustrate how variation is created through sexual reproduction allow me to use an analogy where playing cards represent genetic information. Imagine you take a complete deck of cards sans the joker and partition them out such that you have all the heart and spade suits and your reproductive partner has all the diamonds and club suits. The red colored suits (diamonds and hearts) represent the original genetic material inherited from your mother's side and the black suits (clubs and spades) denote the original genetic material inherited from the father's side. Each of these cards would signify a chromosome, a strand of DNA that has a variety of genes which code for traits. Since you would have two copies of each chromosome - a heart and spade set of ace, 2, 3, 4, 5, 6, 7, 8, 9, 10, jack, queen and king - you are considered a diploid (di - two) individual. So is your reproductive partner who has the diamond and club suit of the same cards. In this example you would have a total chromosome count of only 26 where in reality humans have a total chromosome count of 46 but this simplified example will illustrate how inheritance and a majority of the variation occurs.Your diploid genome - 1/2 the genetic material from your dad, 1/2 from your mom.When you go to reproduce sexually you make gamete cells, either sperm or eggs depending upon your biological sex. To make those cells you randomly draw a single card from either the heart or spade suit to create a cell that has only one copy of each card - ace through king. This new cell would have a chromosome count of only 13, half of what you have, and is called a haploid cell. Your partner is doing the same thing with their cards, creating a haploid cell that contains ace through king cards randomly chosen from the diamond and club set they contain. When those two haploid cells fuse, a process called fertilization, you recreate a diploid individual who has two copies of each of the cards ace through king. So in sexual reproduction it is a reduction in total genetic material (in haploid gametes) and then a reconstitution of the total genetic material during fertilization.The traits encoded in the genes on the chromosome, represented by the playing cards, get passed from parent to offspring as intake distinct "particles". Variation is also created in this process because when the gametes are formed the single chromosome donated to the cell came about from randomly drawing from the two possible sources. Imagine you are actually flipping a coin to decide which card to choose with the rule that heads picks the red card and tails picks the black card. You could randomly draw all the red cards to make your gamete, improbable but not impossible. It would require flipping 13 heads in a row which for a fair coin the probability of occurring is 1 out of 8192 times. Improbable but not impossible. The inverse is true for drawing only black cards. Most likely the gamete would contain a mixture of red and black cards for the ace through king cards. But even then, you could create a large number of possible combinations of just those thirteen cards - 8192 to be exact. You then repeat the process for the other gamete and it is easy to see how many different combinations of chromosome pairs the new fertilized gamete can contain. This process of creating genetic variation through random drawing of each chromosome is called independent assortment, that is each chromosome independently assorts into the gamete cell.One of 8192 possible haploid gametes you could makeAs you imagine all the probable outcomes of creating this gamete it becomes clear that you could create a great diversity of gametes - in humans with 23 pairs of chromosomes you can create 223=8,388,608 genetically different gametes! On top of this source of variation, there is also a phenomenon called crossing over where two sister chromosomes - in our example imagine two of the cards of the same value, e.g., the queen cards - break apart and recombine with each other. So take your queen of hearts and queen of spades, stack them together, rip them randomly in two and then tape the two opposite colored halves back together to create a queen card that now has top half red and bottom half black and the other card is the inverse, top half black and bottom half red. This would then allow traits on one chromosome to be combined with traits on a completely separate chromosome so they are now being inherited together. Assuming these traits were housed on the same chromosome, which is not true, imagine grandma had brown eyes and was farsighted, whereas grandpa had blue eyes but had normal vision and all of these traits were on the same chromosome. Now with crossing over, we have a chromosome with grandmas brown eyes and grandpas normal vision and grandpas blues eyes now combined with farsightedness. A crude approximation of crossing over creating two new chromosomes.As you can see with crossing over and independent assortment occurring you can appreciate the great array of genetic diversity that can be created in the offspring during sexual reproduction.The opening and closing theme to Discovering Darwin is "May" by Jared C. Balogh. http://freemusicarchive.org/music/Balogh/Revitalized_Eyes/MAY Copyright: Attribution-NonCommercial-ShareAlike: http://creativecommons.org/licenses/by-nc-sa/3.0/ Interlude music if Frenchy's String Band "Sunshine Special" recorded in Texas sometime around 1927. https://archive.org/details/FrenchysStringBand-SunshineSpecial
Gary has mentored over 1000 Business Startups, he was a President of an Association of 10,000 entrepreneurs and is a Certified Business Counselor. As an Agent of Change using Social Media he helped change Canadian Law. His current book is How to Start a Successful Business – the First Time. Below are two free resources to IGNITE your Entrepreneurial journey!FreePodcastCourse.com: A free 15-day course that will teach you how to create, grow, and monetize YOUR Podcast!TheWebinarCourse.com: A free 10-day course that will teach you how to create and present Webinars that convert!
Gary Bizzo: Writer of “How to Start a Successful Business the First Time”. He has a coach and mentoring business and recently started an incubator, accelerator and financing company that offers workshops and very basic business courses to run a business. Ideas for retired baby boomers Retired Caretaker: Move into a residential apartments and take...16. Receive Financing ($1million) and Training if You’ve Got a Great Idea- Gary Bizzo was first posted on May 21, 2015 at 7:21 am.©2015 "Income For Baby Boomers". Use of this feed is for personal non-commercial use only. If you are not reading this article in your feed reader, then the site is guilty of copyright infringement. Please contact me at kensproperties@hotmail.com
Chatting With Champions: Interviews With Successful Entrepreneurs
Chatting With Champions Podcast Interview #49. Tyler Basu and Gary Bizzo “How To Start A Successful Business The First Time” Gary Bizzo has been fulfilling the needs of small to medium The post Gary Bizzo: How To Start A Successful Business The First Time appeared first on Chatting With Champions.
Gary has mentored over 1,000 Business Startups, was a President of an Association of 10,000 entrepreneurs, and is a Certified Business Counselor. As an Agent of Change, he has used Social Media to help change Canadian Law. His current book is How to Start a Successful Business – the First Time.