Podcasts about serm

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Latest podcast episodes about serm

Sabiduría para el Corazón
Rasgos de un discípulo de Jesucristo

Sabiduría para el Corazón

Play Episode Listen Later Jun 19, 2025 28:30


(Estudio del evangelio de Lucas, lección 28) Es fácil caer en la tentación de proyectar una imagen diferente de quien realmente somos. Sin embargo, cuando Jesús predicó en el Sermón del Monte, él reveló el verdadero carácter de quienes le siguen, dejando al descubierto la condición real de nuestro corazón. Jesús nos llama a examinarnos con honestidad y reflejar ciertas características que deben marcar a sus seguidores. Pasaje Bíblico: Lucas 6:38-45

El Ritmo de la Mañana
Cosas que si por el nombre deberían de ser más bonita

El Ritmo de la Mañana

Play Episode Listen Later Jun 18, 2025 10:37


ESNE - Enamórate
¿Son bienaventurados los que lloran?

ESNE - Enamórate

Play Episode Listen Later Jun 16, 2025 22:05


Las bienaventuranzas son las enseñanzas que Jesús nos dio en el Sermón de la Montaña, éstas nos muestran el camino a la felicidad. Y el día de hoy aprenderemos la que dice "bienaventurados los que lloran" para entender mejor el sufrimiento y dolor en nuestras vidas. ¡Quédate con nosotros aquí en Enamórate con Lupita Venegas y aprendamos juntos esta gran enseñanza!

Daniel Ramos' Podcast
Episode 485: 16 de Junio del 2025 - Devoción matutina para Adultos - ¨Con Jesús Hoy"

Daniel Ramos' Podcast

Play Episode Listen Later Jun 15, 2025 5:09


====================================================SUSCRIBETEhttps://www.youtube.com/channel/UCNpffyr-7_zP1x1lS89ByaQ?sub_confirmation=1====================================================DEVOCIÓN MATUTINA PARA ADULTOS 2025“CON JESÚS HOY”Narrado por: Exyomara AvilaDesde: Bogotá, ColombiaUna cortesía de DR'Ministries y Canaan Seventh-Day Adventist Church ===================|| www.drministries.org ||===================16 de JunioPacificadores«Bienaventurados los pacificadores, porque serán llamados hijos de Dios» (Mat. 5: 9).En el Sermón del Monte Jesús se presenta como el gran apóstol de la no violencia, es decir, de su plan divino para que aprendamos a convivir felices y libres en un mundo en paz:

La Vida Que Quiero
Cómo ser asertiva y atreverte a decir lo que quieres y necesitas

La Vida Que Quiero

Play Episode Listen Later Jun 15, 2025 32:10


Saber lo que necesitas no sirve de nada si no te atreves a decirlo. En este episodio hablamos de cómo dar ese paso que tanto cuesta: expresar lo que sientes, poner tus límites y hacerte valer sin miedo a incomodar. Si siempre te adaptas, si callas para no molestar o te cuesta pedir sin culpa, este episodio es para ti. Porque ser asertiva no es ser borde: es respetarte. Y hablar desde ti —aunque tiemble la voz— es el principio de tu libertad emocional. ⭐ Accede GRATIS aquí a mi curso: Ser Más Feliz.  ♥️ Únete a mi membresía TENERTE A TI MISMA para aprender a sanar tu relación contigo y reconstruir tu autoestima: https://tenerteatimismo.com/

Igreja Presbiteriana Redenção
JOÃO 3.9-21 - A maior demonstração de amor da história

Igreja Presbiteriana Redenção

Play Episode Listen Later Jun 15, 2025 44:47


Sermão ministrado pelo Rev. Lucas Carvalho com base em João 3.9-21. Igreja Presbiteriana Redenção.

Igreja Presbiteriana Redenção
1 SAMUEL 9.1 - 10.16 - A Providência e os Propósitos de Deus

Igreja Presbiteriana Redenção

Play Episode Listen Later Jun 15, 2025 74:06


Sermão ministrado pelo Rev. Luciano Vieira com base em 1 Samuel 9.1 - 10.16. Igreja Presbiteriana Redenção.

SER Málaga
SER Deportivos Málaga (13/06/2025)

SER Málaga

Play Episode Listen Later Jun 13, 2025 39:45


El espacio de deportes en SER Málaga de la Cadena SER

Catholic Daily Reflections
Friday of the Tenth Week in Ordinary Time - The Love of Friendship

Catholic Daily Reflections

Play Episode Listen Later Jun 12, 2025 6:21


Read OnlineIf your right eye causes you to sin, tear it out and throw it away. It is better for you to lose one of your members than to have your whole body thrown into Gehenna. And if your right hand causes you to sin, cut it off and throw it away. It is better for you to lose one of your members than to have your whole body go into Gehenna. Matthew 5:29–30This imagery of tearing out your eye and cutting off your hand is clearly meant to get our attention. Though we can be certain that Jesus is not actually suggesting we mutilate our bodies, we should not hesitate to prayerfully ponder this imagery so as to understand the truths Jesus is speaking.Saint Augustine, in reflecting upon this passage, states: “By the eye we must understand our most cherished friend…” Augustine further points out that Jesus specifically mentions the “right eye” as a way of denoting those friendships that have a “higher degree of affection” (Serm. in Mont. i. 13.). Thus, although friendship—especially very close friendship—is a gift, sometimes those close to us can become a source of sin or an occasion of sin. In that case, they are not truly friends, and it might be better to limit or even end that relationship rather than to allow it to lead us into sin.Think about the people in your own life. Though we must love all people with the love of God, friendship is more than love. Friendship establishes a special bond with another and opens you up to their presence and influence in your life. When you establish a friendship, you allow another a certain influence in your life. When that influence is good, then the friendship produces much good fruit. But when that influence is evil, then that friendship becomes a danger to the good of your soul. In that case, it may need to be torn out or cut off so that you are not drawn into serious sin or even the occasion of sin.When a friend in your life becomes an occasion of sin to you, your love for them must remain, but it must also change. Love, in this case, may take on the form of a loving rebuke, a withdrawal of your own heart, or a limiting of your interactions. But this is love. By analogy, when a person sins against God, their relationship with God also changes. God withdraws His friendship. He is less present to the person, and their internal communion diminishes or even ends when the sin is serious. This is not a lack of love on God's part; it is simply the effect of sin. So also in our relations with another, when the grace of God is not mutually given and received between two people, then friendship in the truest sense is not possible. True friendship is always centered in God's grace and dependent upon it. Therefore, when God is excluded from a relationship, that relationship must change from a true friendship to a relationship that imitates God's love for a sinner. Mercy, compassion and forgiveness must continually be offered, but interior communion and unity will end. But this is love.Reflect, today, upon those in your life whom God has given you to love. First, reflect upon those relationships that do have God at the center. These relationships will become true friendships and will produce an abundance of good fruit in your life. Rejoice in these friendships and give thanks to God for them. Second, reflect upon any relationship that does not bear good fruit. As you do, prayerfully consider how you approach that relationship. Do you attempt to maintain a “friendship” even though God is not able to be the center of that relationship? If so, ponder how God is calling you to change that relationship so that it more fully reflects the love God has for you and for that other person in your life.My Lord and true Friend, I thank You for loving me with a perfect love. I pray that I will always be open to that love so that my unity with You will ever deepen. I also pray that I will be an instrument of Your love to others. Please give me the grace to love everyone in my life in the way that You love them, nothing less and nothing more. Jesus, I trust in You.Image:  El Salvador beneint by Lluís Ribes Mateu, license CC BY-NC 2.0Source of content: catholic-daily-reflections.comCopyright © 2025 My Catholic Life! Inc. All rights reserved. Used with permission via RSS feed.

P4Cast
P4Cast 330 - Vivendo a cultura do sobrenatural - Pr. Rodrigo Freitas

P4Cast

Play Episode Listen Later Jun 12, 2025 79:28


Mensagem gravada em 08/06/2025 Pastor Rodrigo FreitasVivendo a cultura do sobrenatural Mateus 16:13-20 NVI[13] Chegando Jesus à região de Cesareia de Filipe, perguntou aos seus discípulos: “Quem os outros dizem que o Filho do homem é?” [14] Eles responderam: “Alguns dizem que é João Batista; outros, Elias; e, ainda outros, Jeremias ou um dos profetas”. [15] “E vocês?”, perguntou ele. “Quem vocês dizem que eu sou?” [16] Simão Pedro respondeu: “Tu és o Cristo, o Filho do Deus vivo”. [17] Respondeu Jesus: “Feliz é você, Simão, filho de Jonas! Porque isto não foi revelado a você por carne ou sangue, mas por meu Pai que está nos céus. [18] E eu digo que você é Pedro, e sobre esta pedra edificarei a minha igreja, e as portas do Hades não poderão vencê-la. [19] Eu darei a você as chaves do Reino dos céus; o que você ligar na terra terá sido ligado nos céus, e o que você desligar na terra terá sido desligado nos céus”. [20] Então advertiu a seus discípulos que não contassem a ninguém que ele era o Cristo.https://bible.com/bible/129/mat.16.13-20.NVI 1 Pedro 2:4-10 NVI[4] À medida que se aproximam dele, a pedra viva—rejeitada pelos homens, mas escolhida por Deus e preciosa para ele—, [5] vocês também estão sendo utilizados como pedras vivas na edificação de uma casa espiritual para serem sacerdócio santo, oferecendo sacrifícios espirituais aceitáveis a Deus, por meio de Jesus Cristo. [6] Pois assim é dito na Escritura: “Eis que ponho em Sião uma pedra angular, escolhida e preciosa, e aquele que nela confia jamais será envergonhado”. [7] Portanto, para vocês, os que creem, esta pedra é preciosa; mas, para os que não creem, “a pedra que os construtores rejeitaram tornou-se a pedra angular” [8] e “pedra de tropeço e rocha que faz cair”. Os que não creem tropeçam, porque desobedecem à mensagem; para o que também foram destinados. [9] Vocês, porém, são geração eleita, sacerdócio real, nação santa, povo exclusivo de Deus, para anunciar as grandezas daquele que os chamou das trevas para a sua maravilhosa luz. [10] Antes vocês nem sequer eram povo, mas agora são povo de Deus; não haviam recebido misericórdia, mas agora a receberam.https://bible.com/bible/129/1pe.2.4-10.NVI #Jesus #igreja #honra #transformação #Jesus #ressurreição #PalavraDeDeus #DeusPai #EspiritoSanto #PAI #Mensagem #Pregação #Sermão #p4 #p4church #onLine --Curta, compartilhe e inscreva-se para ficar atualizado com os nossos conteúdos!Para saber mais sobre nossa igreja:Site: https://igrejaprojeto4.com.br/Faça seu pedido de Oração: https://igrejaprojeto4.com.br/pedidosFacebook: https://www.facebook.com/p4church/Instagram:  https://www.instagram.com/igrejaprojeto4/Podcast:  https://igrejaprojeto4.com.br/p4cast/Youtube:  [https://www.youtube.com/@IgrejaProjeto4](https://www.youtube.com/IgrejaProjeto4)- --Culto online todos os domingos no YouTube!

SER Málaga
SER Deportivos Málaga (12/06/2025)

SER Málaga

Play Episode Listen Later Jun 12, 2025 39:41


El espacio de deportes en SER Málaga de la Cadena SER

AuDios Cristianos Sencillos
RESUMIENDO EL SERMÓN. Mateo 11

AuDios Cristianos Sencillos

Play Episode Listen Later Jun 12, 2025 7:38


Este capítulo marca un punto de transición y el comienzo de una fase del ministerio de Jesús caracterizada por una creciente oposición y desilusión. Presenta temas clave como la duda, la identidad de Jesús, el rechazo del mensaje y lasoberanía de Dios en la revelación y la salvación. La estructura general puede dividirse en tres secciones principales después del versículo de transición.I. Transición en el Ministerio de Jesús (Mateo 11:1)II. La Duda de Juan el Bautista y el Juicio de Jesús sobre la Generación Impenitente (Mateo 11:2-19)III. Juicio y Misericordia: La Oportunidad Rechazada y la Invitación (Mateo 11:20-30)

Yeni Şafak Podcast
Süleyman Seyfi Öğün-Katı ve yumuşak

Yeni Şafak Podcast

Play Episode Listen Later Jun 12, 2025 6:53


Emek ve sermâye açısından kapitalizmin en derin çelişkisi sâdece birikim odaklı değildir. Bu aynı zamanda dolaşım boyutunda da tezâhür eder. Sermâye kendisini büyütmek adına, engellenmeden dolaşımda olmak zorundadır. Girdiği her yerde, çektiği artığı büyütmek isteyecektir. Sömürgecilik ve emperyalizm bize bunun açılımlarını verir.

SER Málaga
SER Deportivos Málaga (11/06/2025)

SER Málaga

Play Episode Listen Later Jun 11, 2025 39:59


El espacio de deportes en SER Málaga de la Cadena SER

Igreja Anglicana Âncora
Seremos como a luz da manhã | Bispo Eric Rodrigues

Igreja Anglicana Âncora

Play Episode Listen Later Jun 10, 2025 53:07


Sermão de domingo (08/06/25), Domingo de Pentecostes. Texto base se encontra em João 16,33.Nesse sermão, aprendemos que vivemos numa ditadura da performance onde tudo precisa ser filmável, então estamos cansados de tentar “dar certo” o tempo todo. Que nossa alma só vai repousar de fato quando estiver cheia do Espírito Santo. Que Jesus não nos ilude quanto às tribulações da vida, mas também não nos deixa só. A obra do Espírito Santo é nos fazer um com Cristo.Coleta de Pentecostes: “Ó Espírito Santo, criador e doador da vida, vinde mais uma vez a nós. Inquieta-nos, ó Espírito Santo, com Teu fogo santo e nos mova para onde quiseres. Enche-nos, mais uma vez, nós te suplicamos, para que amemo-nos uns aos outros, assim como Cristo nos ama; para que sejamos um, assim como Pai, Filho e Espírito Santo são um; para que anunciemos com coragem e alegria aquilo do qual somos testemunhas; para que façamos a vontade do Pai até as últimas consequências, assim como Jesus Cristo a fez quando suportou a morte de cruz. Por Jesus Cristo, nosso Senhor, que vive e reina contigo e Deus Pai, agora e para todo o sempre.Amém.”

Interioriza - com Iza Camargo
E se eu não quiser ser mãe? Como se proteger das pressões com Aline Wolff e Juliana Teixeira

Interioriza - com Iza Camargo

Play Episode Listen Later Jun 10, 2025 40:40


Por que sentimos tanta culpa até ao descansar?No @interior_iza desta terça-feira (10/06), recebo Aline Wolff (@alinewolffpsi), psicóloga do Comitê Olímpico Brasileiro (@timebrasil), e Juliana Teixeira Gomes (@julianateixeira.gineco), ginecologista e obstetra, para falar sobre maternidade, carreira e a pressão invisível que faz muitas mulheres se sentirem culpadas até quando cuidam da própria saúde.Descanso não é luxo. É base para uma performance sustentável, dentro ou fora de casa.Inscreva-se em nosso canal @IzabellaCamargoreal https://www.instagram.com/interior_iza https://www.instagram.com/izabellacamargoreal https://www.tiktok.com/@izabellacamargoreal Convidadoswww.instagram.com/alinewolffpsiwww.instagram.com/julianateixeira.ginecoEste episódio tem o #patrocínio por @clearblue.Quero agradecer também a @jubutlerbabyshopper, @pripripacifico e @sonhosdeninar por esse cenário lindo e a @emmafiorezi por esse look maravilhoso desse episódio!! #IzabellaCamargo #PodcastInterioriza #EspecialMaternidade #SaúdeMental #AlineWolff #JulianaTeixeiraGomes #CarreiraEFamília #BemEstar #ProdutividadeSustentável

Entrenamiento Hoy
Cómo ser más constante en cualquier cosa

Entrenamiento Hoy

Play Episode Listen Later Jun 10, 2025 8:16


Para lograr buenos resultados en cualquier cosa que te propongas necesitas constancia.En este episodio te cuento algunas cosas que a personalmente me han ayudado a conseguirlo.Apúntate a la newsletter en: https://www.lifters.es

La Vida Que Quiero
Cómo soltar el resentimiento (sin forzarte a perdonar)

La Vida Que Quiero

Play Episode Listen Later Jun 9, 2025 32:51


¿Sientes que no puedes pasar página, aunque haya pasado el tiempo? ¿Sigues dándole vueltas a lo que te hicieron, como si revivieras una y otra vez la misma escena? En este episodio te hablo de por qué cuesta tanto soltar el resentimiento, qué función inconsciente cumple en tu vida y cómo liberarte de esa carga sin traicionarte a ti misma. No se trata de justificar al otro ni de reconciliarte con nadie. Se trata de recuperar tu paz, tu energía y tu capacidad de abrirte de nuevo a la vida. ⭐ Accede GRATIS aquí a mi curso: Ser Más Feliz.  ♥️ Únete a mi membresía TENERTE A TI MISMA para aprender a sanar tu relación contigo y reconstruir tu autoestima: https://tenerteatimismo.com/

Igreja Presbiteriana de Irajá
Culto noturno - 08/06

Igreja Presbiteriana de Irajá

Play Episode Listen Later Jun 9, 2025 38:14


Canal oficial da Igreja Presbiteriana do Brasil em Irajá. Igreja cristã, reformada e com o intuito de glorificar o nome de Jesus Cristo. Venha nos visitar e participar de uma reunião conosco. Estamos nas redes sociais com o @presbiterianadeiraja.Sermão: Sem. Wellerson Samuel - Culto noturno - 09/06/2025

Igreja Presbiteriana de Irajá
Quando Deus muda o decreto

Igreja Presbiteriana de Irajá

Play Episode Listen Later Jun 9, 2025 34:00


Canal oficial da Igreja Presbiteriana do Brasil em Irajá. Igreja cristã, reformada e com o intuito de glorificar o nome de Jesus Cristo. Venha nos visitar e participar de uma reunião conosco. Estamos nas redes sociais com o @presbiterianadeiraja.Sermão: Rev. Carlos Alberto Monteiro - Culto matutino - 08/06/2025

Sermões do Instituto Bom Pastor
A caridade do Espírito Santo contra o orgulho luciferino do Liberalismo (08.06.2025)

Sermões do Instituto Bom Pastor

Play Episode Listen Later Jun 9, 2025 23:20


Sermão para o Domingo de PentecostesPadre Marcos Mattke, IBP.Capela Nossa Senhora das Dores, Brasília.

Sermões do Instituto Bom Pastor
Soldados ou desertores? O que fizemos da nossa Crisma? (08.06.2025)

Sermões do Instituto Bom Pastor

Play Episode Listen Later Jun 9, 2025 21:39


Sermão para o Domingo de PentecostesPadre Ivan Chudzik, IBP.Igreja Nossa Senhora do Rosário dos Homens Pretos, Belém/PA.

Sermões do Instituto Bom Pastor
O testemunho do Espírito Santo. (01.06.2025)

Sermões do Instituto Bom Pastor

Play Episode Listen Later Jun 9, 2025 23:26


Sermão para a Festa da AscensãoPadre Thiago Bonifácio, IBP.Oratório da Imaculada Conceição – Curitiba/PR.

Sermões do Instituto Bom Pastor
Quem sou eu no confessionário? Parte 2 (01.06.2025)

Sermões do Instituto Bom Pastor

Play Episode Listen Later Jun 9, 2025 25:17


Sermão para a festa da Ascensão. Padre Ivan Chudzik, IBP.Igreja Nossa Senhora do Rosário dos Homens Pretos,Belém/PA.

Sermões do Instituto Bom Pastor
Para melhor fazer as orações vocais (04.06.2025)

Sermões do Instituto Bom Pastor

Play Episode Listen Later Jun 9, 2025 14:45


Sermão para o Domingo na Oitava da AscensãoPadre Leonardo Carvalho, IBP.Capela Nossa Senhora das Dores, Brasília

Cartas de um Terapeuta
#118 - É possível gostar de ser mãe de adolescente?

Cartas de um Terapeuta

Play Episode Listen Later Jun 5, 2025 30:27


Neste episódio, Vanda (nome fictício) me escreve, irritada com uma fala minha em que eu disse que estava amando ser pai de adolescente. Eu respondo ao bilhete dela com uma conversa sobre o diálogo possível com eles, e sobre como nós, culturamente, andamos muito mal na forma de reconhecer a beleza possível que eles trazem para o mundo. Então dê o play e venha para mais um CARTAS DE UM TERAPEUTA!As cartas são a escrita que a alma faz, sem rodeios, para as perguntas que nos inquietam, para aquilo que nos atravessa, para a vida que tem urgência de ser dita. Em palavras faladas, as cartas são o sopro que nos conecta por um instante. Abra este envelope, ele é pra você. Vai começar mais um episódio do “Cartas de um terapeuta”.Cartas de um Terapeuta é um podcast apresentado por Alexandre Coimbra Amaral.E para enviar a sua carta o e-mail é: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠alexandrecoimbraamaral@gmail.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Produzido por Abrace Podcasts. Visite-nos em ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://abrace.digital/⁠⁠⁠⁠⁠⁠⁠⁠Esta temporada é apresentada por Avatim. Acesse o link ⁠⁠⁠https://bit.ly/cartas-e-avatim⁠⁠⁠ e use o cupom CARTAS15 para garantir 15% de desconto em todos os produtos do site.

Rede Paizinho, Vírgula!
#118 - É possível gostar de ser mãe de adolescente?

Rede Paizinho, Vírgula!

Play Episode Listen Later Jun 5, 2025 30:27


Neste episódio, Vanda (nome fictício) me escreve, irritada com uma fala minha em que eu disse que estava amando ser pai de adolescente. Eu respondo ao bilhete dela com uma conversa sobre o diálogo possível com eles, e sobre como nós, culturamente, andamos muito mal na forma de reconhecer a beleza possível que eles trazem para o mundo. Então dê o play e venha para mais um CARTAS DE UM TERAPEUTA!As cartas são a escrita que a alma faz, sem rodeios, para as perguntas que nos inquietam, para aquilo que nos atravessa, para a vida que tem urgência de ser dita. Em palavras faladas, as cartas são o sopro que nos conecta por um instante. Abra este envelope, ele é pra você. Vai começar mais um episódio do “Cartas de um terapeuta”.Cartas de um Terapeuta é um podcast apresentado por Alexandre Coimbra Amaral.E para enviar a sua carta o e-mail é: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠alexandrecoimbraamaral@gmail.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Produzido por Abrace Podcasts. Visite-nos em ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://abrace.digital/⁠⁠⁠⁠⁠⁠⁠⁠Esta temporada é apresentada por Avatim. Acesse o link ⁠⁠⁠https://bit.ly/cartas-e-avatim⁠⁠⁠ e use o cupom CARTAS15 para garantir 15% de desconto em todos os produtos do site.

Lo que hay que saber
Cristina Kirchner será candidata a legisladora bonaerense; la nafta será más barata de madrugada

Lo que hay que saber

Play Episode Listen Later Jun 3, 2025 2:05


Resumen de noticias de la mañana de LA NACION del 3 de junio de 2025 

PazConDios — Capacitando líderes para equipar a la iglesia
Cantar a Dios Desarrolla Raíces Profundas | Raíces Profundas #5

PazConDios — Capacitando líderes para equipar a la iglesia

Play Episode Listen Later Jun 3, 2025 29:55


Acabamos de publicar el Sermón de la Semana: Cantar a Dios Desarrolla Raíces Profundas. En este mensaje, aprendemos que los hijos de Dios deben cantar las alabanzas de su gran Dios y Rey siempre, a diario.. ¡Usálo en tu ministerio! En www.PazConDios.com puedes conseguir el bosquejo detallado de este mensaje para poder usarlo en tu iglesia. También, en esta página hay muchísimos recursos para líderes de la iglesia, y todo completamente gratis.En www.PazConDios.com nuestra misión es equipar a los santos para hacer la obra del ministerio.¡Todo es completamente gratis!Libros: http://pazcondios.com/?page_id=5095Sermones: http://pazcondios.com/?cat=23Seminarios: http://pazcondios.com/?page_id=5121Artículos: http://pazcondios.com/?cat=144¿Preguntas?: preguntas@pazcondios.com¿Consultas del liderazgo?: consejos@pazcondios.comMúsica de PazConDios: https://www.youtube.com/@pazcondiosmusicaTodos los videos: https://www.youtube.com/watch?v=RUF3Gp6FTm0&list=UULFMPaf3L9StVNggFJD7O-KCwTalleres para Líderes: https://www.youtube.com/watch?v=Adol5569wjY&list=PLxsoGHoYj9T8Zle1xyiwD2-SeCudWNOj_Preguntas cortas: https://www.youtube.com/watch?v=RUF3Gp6FTm0&list=PLxsoGHoYj9T-28D2co2gJmEJOMLVvXyNGSermones: https://www.youtube.com/watch?v=JshB0JRyjxM&list=PLxsoGHoYj9T8PubRdWl8jUjqNvR0YNzpjPreguntas y Respuestas EN VIVO: https://www.youtube.com/watch?v=mYgWrC3GTyw&list=PLxsoGHoYj9T-1JqRpVgXRcWTsap8aVLgjEn www.PazConDios.com, proveemos recursos para líderes en la iglesia. Nuestra misión es equipar a los santos para hacer la obra del ministerio. Visítanos en www.PazConDios.com para encontrar toda clase de recursos para líderes completamente gratis.

Hoy por Hoy
La economía de Hoy por Hoy | La factura de la luz en el mes de mayo será más cara por culpa del apagón

Hoy por Hoy

Play Episode Listen Later Jun 2, 2025 4:49


El análisis de actualidad económica, todas las mañanas a las 07:30. 

Igreja Presbiteriana de Irajá
Quais são os processos da vida cristã?

Igreja Presbiteriana de Irajá

Play Episode Listen Later Jun 2, 2025 36:40


Canal oficial da Igreja Presbiteriana do Brasil em Irajá. Igreja cristã, reformada e com o intuito de glorificar o nome de Jesus Cristo. Venha nos visitar e participar de uma reunião conosco. Estamos nas redes sociais com o @presbiterianadeiraja.Sermão: Rev. Carlos Alberto Monteiro - Culto noturno - 01/06/2025

Igreja Presbiteriana de Irajá
Quando Deus rejeita o culto

Igreja Presbiteriana de Irajá

Play Episode Listen Later Jun 2, 2025 50:24


Canal oficial da Igreja Presbiteriana do Brasil em Irajá. Igreja cristã, reformada e com o intuito de glorificar o nome de Jesus Cristo. Venha nos visitar e participar de uma reunião conosco. Estamos nas redes sociais com o @presbiterianadeiraja.Sermão: Rev. Carlos Alberto Monteiro - Culto matutino - 01/06/2025

Mil Palabras
#288 Hablar en público no es lucirse, es servir

Mil Palabras

Play Episode Listen Later May 30, 2025 23:05


Hablar en público no es lucirseEl objetivo principal de hablar en público no es ser brillante. Ni ser gracioso. Ni parecer interesante. Hablar en público se trata de servir. Y eso cambia todo. Te explico.Hablar en público no es lucirse, es servir¿Te da susto hablar en público? Bueno, es normal. A la mayoría nos ha pasado. El problema es que creemos que estamos ahí para demostrar algo: inteligencia, carisma, talento. Cuando en realidad estamos ahí para otra cosa.Estamos ahí para ayudar.Hablar en público es, ante todo, un acto de servicio. Es compartir algo que puede hacerle bien a otro. Una idea, una historia, un dato. Un punto de vista. Un chiste, incluso. No para que se rían de ti, sino para que se rían contigo.Cuando dejas de pensar en “lucirte” y empiezas a pensar en “servir”, algo se desbloquea. Ya no es tu ego el que está en juego. Es tu mensaje. Es lo que puedes dejarle al otro. Y ahí, mágicamente, baja el miedo.¿Cómo se ve eso en la práctica?– No memorices discursos, entiende el mensaje que quieres dejar.– No hables como experto, habla como alguien que quiere ayudar.– No esperes aplausos, espera conexión.– No temas equivocarte, teme no aportar.Una vez un conocido dio una charla con la camisa algo arrugada. Era una tela delicada y probablemente el ajetreo previo y el haberse sentado en algún sofá, se la desorganizaron un poco. Al principio se sintió fatal. Después, se concentró en el tema. Nadie mencionó la camisa. Pero sí le escribieron varios para agradecerle el contenido. Y ahí el y yo entendimos: el orador no era el protagonista. Era el mensaje.Si vas a hablar en público, piensa a quién puedes servir con eso que sabes o que has vivido. Porque no se trata de parecer brillante, sino de ser útil.En este episodio te comparto algunas historias de sacerdotes que se quieren lucir en su sermón, y su palabra no impacta. No es que este sea un episodio religioso ni mucho menos.#Hablar en público, #Oratoria, #Comunicación efectiva, #Miedo escénico, #Servicio al comunicar, #Santiago Ríos, #Mil Palabras, #Marca personal, #Storytelling, #Habilidades blandas, #Presentaciones, #Podcast, #Podcast Corporativo, #Sermón, #Cura, #Misa, #SacerdoteRecuerda por favor escucharnos y suscribirte en la plataforma que más te guste:https://podcasts.apple.com/co/podcast/mil-palabras/id1472769024 https://open.spotify.com/show/4ntUNh1i9rPue1MkeuEYLs http://bit.ly/googleMPhttps://www.spreaker.com/podcast/mil-palabras--4898895https://www.deezer.com/mx/show/1872052Para participar, escríbeme tus comentarios a santiagorios@milpalabras.com.coRecursos recomendados en este PodcastSuscríbete al http://www.milpalabras.com enhttp://www.milpalabras.comDescarga GRATIS el ebook “Cómo Crear un Podcast Corporativo”https://milpalabras.com.co/Otros podcasts recomendados de nuestra redUn café con tu futuroLas mejores prácticas empresariales para crecer como profesional y como persona.

Mindalia.com-Salud,Espiritualidad,Conocimiento
¿Cómo hablar con fallecidos? ¿Tú podrías ser MÉDIUM? | Raúl Vaquero Médium

Mindalia.com-Salud,Espiritualidad,Conocimiento

Play Episode Listen Later May 28, 2025 39:46


En Ivoox puedes encontrar sólo algunos de los audios de Mindalia. Para escuchar las 4 grabaciones diarias que publicamos entra en https://www.mindaliatelevision.com. Si deseas ver el vídeo perteneciente a este audio, pincha aquí: https://www.youtube.com/watch?v=l8e3kbH2xEU ¿Es posible comunicarse con los que han partido? ¿Tienes señales, sueños o intuiciones y no sabes qué significan? Raúl Vaquero, médium, revela cómo funciona la conexión con el más allá y si cualquier persona puede desarrollar esta capacidad. Descubre los secretos de la mediumnidad y aprende a interpretar los mensajes del otro lado. ¡No es casualidad que estés aquí! Raúl Vaquero Médium Médium mundialmente reconocido. Más información en: https://www.mindalia.com/television/ PARTICIPA CON TUS COMENTARIOS EN ESTE VÍDEO. -----------INFORMACIÓN SOBRE MINDALIA--------- Mindalia.com es una ONG internacional, sin ánimo de lucro, que difunde universalmente contenidos sobre espiritualidad y bienestar para la mejora de la consciencia del mundo. Apóyanos con tu donación en: https://www.mindalia.com/donar/ Suscríbete, comenta positivamente y comparte nuestros vídeos para difundir este conocimiento a miles de personas. Nuestro sitio web: https://www.mindalia.com SÍGUENOS TAMBIÉN EN NUESTRAS PLATAFORMAS Facebook: / mindalia.ayuda Instagram: / mindalia_com Twitch: / mindaliacom Odysee: https://odysee.com/@Mindalia.com *Mindalia.com no se hace responsable de las opiniones vertidas en este vídeo, ni necesariamente participa de ellas.

La Vida Que Quiero
Sincronicidades: Cuando la vida te habla - Cómo desarrollar una espiritualidad sin intermediarios

La Vida Que Quiero

Play Episode Listen Later May 28, 2025 35:22


¿Sientes que la vida te está hablando pero no sabes cómo escucharla? En este episodio hablamos de espiritualidad sin dogmas, de sincronicidades como lenguaje simbólico y de cómo desarrollar una conexión directa con la vida que te dé sentido, pertenencia y dirección, especialmente en los momentos más difíciles. ⭐ Accede GRATIS aquí a mi curso: Ser Más Feliz. ❤️‍

Iglesia Presbiteriana Westminster - EPC
Buena Ocasión Para Una Nueva Orden  - Sermón 17 de abril de 2025

Iglesia Presbiteriana Westminster - EPC

Play Episode Listen Later May 28, 2025 22:07


Juan 13:31-35Support the show

PazConDios — Capacitando líderes para equipar a la iglesia

Acabamos de publicar el Sermón de la Semana: Una Palabra para las Madres. En este mensaje, comparto una palabra de ánimo y guía para las madres.. ¡Usálo en tu ministerio! En www.PazConDios.com puedes conseguir el bosquejo detallado de este mensaje para poder usarlo en tu iglesia. También, en esta página hay muchísimos recursos para líderes de la iglesia, y todo completamente gratis.En www.PazConDios.com nuestra misión es equipar a los santos para hacer la obra del ministerio.¡Todo es completamente gratis!Libros: http://pazcondios.com/?page_id=5095Sermones: http://pazcondios.com/?cat=23Seminarios: http://pazcondios.com/?page_id=5121Artículos: http://pazcondios.com/?cat=144¿Preguntas?: preguntas@pazcondios.com¿Consultas del liderazgo?: consejos@pazcondios.comMúsica de PazConDios: https://www.youtube.com/@pazcondiosmusicaTodos los videos: https://www.youtube.com/watch?v=RUF3Gp6FTm0&list=UULFMPaf3L9StVNggFJD7O-KCwTalleres para Líderes: https://www.youtube.com/watch?v=Adol5569wjY&list=PLxsoGHoYj9T8Zle1xyiwD2-SeCudWNOj_Preguntas cortas: https://www.youtube.com/watch?v=RUF3Gp6FTm0&list=PLxsoGHoYj9T-28D2co2gJmEJOMLVvXyNGSermones: https://www.youtube.com/watch?v=JshB0JRyjxM&list=PLxsoGHoYj9T8PubRdWl8jUjqNvR0YNzpjPreguntas y Respuestas EN VIVO: https://www.youtube.com/watch?v=mYgWrC3GTyw&list=PLxsoGHoYj9T-1JqRpVgXRcWTsap8aVLgjEn www.PazConDios.com, proveemos recursos para líderes en la iglesia. Nuestra misión es equipar a los santos para hacer la obra del ministerio. Visítanos en www.PazConDios.com para encontrar toda clase de recursos para líderes completamente gratis.

Iglesia Presbiteriana Westminster - EPC
No Basta Con Una Mirada - Sermón 13 de abril de 2025

Iglesia Presbiteriana Westminster - EPC

Play Episode Listen Later May 26, 2025 25:24


Juan 12:12-16Support the show

Igreja Presbiteriana de Irajá
Liberdade cristã

Igreja Presbiteriana de Irajá

Play Episode Listen Later May 26, 2025 27:08


Canal oficial da Igreja Presbiteriana do Brasil em Irajá. Igreja cristã, reformada e com o intuito de glorificar o nome de Jesus Cristo. Venha nos visitar e participar de uma reunião conosco. Estamos nas redes sociais com o @presbiterianadeiraja.Sermão: Rev. Carlos Alberto Monteiro - Culto matutino - 25/05/2025

Igreja Presbiteriana de Irajá
Quando Jesus entra na família

Igreja Presbiteriana de Irajá

Play Episode Listen Later May 26, 2025 29:27


Canal oficial da Igreja Presbiteriana do Brasil em Irajá. Igreja cristã, reformada e com o intuito de glorificar o nome de Jesus Cristo. Venha nos visitar e participar de uma reunião conosco. Estamos nas redes sociais com o @presbiterianadeiraja.Sermão: Rev. Carlos Alberto Monteiro - Culto noturno - 25/05/2025

PazConDios — Capacitando líderes para equipar a la iglesia
Cómo experimentar la intensidad del ayuno | Raíces Profundas #4

PazConDios — Capacitando líderes para equipar a la iglesia

Play Episode Listen Later May 24, 2025 29:33


Acabamos de publicar el Sermón de la Semana: Cómo experimentar la intensidad del ayuno. En este mensaje, aprendemos cómo experimentar la intensidad en nuestra búsqueda de Dios que el ayuno trae.. ¡Usálo en tu ministerio! En www.PazConDios.com puedes conseguir el bosquejo detallado de este mensaje para poder usarlo en tu iglesia. También, en esta página hay muchísimos recursos para líderes de la iglesia, y todo completamente gratis.En www.PazConDios.com nuestra misión es equipar a los santos para hacer la obra del ministerio.¡Todo es completamente gratis!Libros: http://pazcondios.com/?page_id=5095Sermones: http://pazcondios.com/?cat=23Seminarios: http://pazcondios.com/?page_id=5121Artículos: http://pazcondios.com/?cat=144¿Preguntas?: preguntas@pazcondios.com¿Consultas del liderazgo?: consejos@pazcondios.comMúsica de PazConDios: https://www.youtube.com/@pazcondiosmusicaTodos los videos: https://www.youtube.com/watch?v=RUF3Gp6FTm0&list=UULFMPaf3L9StVNggFJD7O-KCwTalleres para Líderes: https://www.youtube.com/watch?v=Adol5569wjY&list=PLxsoGHoYj9T8Zle1xyiwD2-SeCudWNOj_Preguntas cortas: https://www.youtube.com/watch?v=RUF3Gp6FTm0&list=PLxsoGHoYj9T-28D2co2gJmEJOMLVvXyNGSermones: https://www.youtube.com/watch?v=JshB0JRyjxM&list=PLxsoGHoYj9T8PubRdWl8jUjqNvR0YNzpjPreguntas y Respuestas EN VIVO: https://www.youtube.com/watch?v=mYgWrC3GTyw&list=PLxsoGHoYj9T-1JqRpVgXRcWTsap8aVLgjEn www.PazConDios.com, proveemos recursos para líderes en la iglesia. Nuestra misión es equipar a los santos para hacer la obra del ministerio. Visítanos en www.PazConDios.com para encontrar toda clase de recursos para líderes completamente gratis.

ASCO Daily News
ASCO25 Preview: Key Research Accelerating Cancer Care

ASCO Daily News

Play Episode Listen Later May 22, 2025 20:42


Dr. John Sweetenham and Dr. Erika Hamilton discuss top abstracts that will be presented at the 2025 ASCO Annual Meeting, including research on tech innovations that could shape the future of oncology. Transcript Dr. John Sweetenham: Hello, and welcome to the ASCO Daily News Podcast. I'm your host, Dr. John Sweetenham, and I'm delighted to be joined today by Dr. Erika Hamilton, a medical oncologist and director of breast cancer and gynecologic cancer research at the Sarah Cannon Research Institute in Nashville, Tennessee. Dr. Hamilton is also the chair of the 2025 ASCO Annual Meeting Scientific Program, and she's here to tell us about some of the key abstracts, hot topics, and novel approaches in cancer care that will be featured at this year's Annual Meeting. Our full disclosures are available in the transcript of this episode. Dr. Hamilton, it's great to have you on the podcast today, and thanks so much for being here. Dr. Erika Hamilton: Thanks, Dr. Sweetenham. I'm glad to be here. Dr. John Sweetenham: Dr. Hamilton, the Presidential Theme of the Annual Meeting this year is ‘Driving Knowledge to Action: Building a Better Future,' and that's reflected in many of the sessions that will focus on action-oriented guidance to improve care for our patients. And as always, there'll be great presentations on practice-changing abstracts that will change treatment paradigms and transform care. Can you tell us about some of the hot topics this year and what you're particularly excited about? Dr. Erika Hamilton: You're right. Dr. Robin Zon's theme is ‘Driving Knowledge to Action: Building a Better Future,' and you're going to see that theme really interlaced throughout the ASCO program this year. We had a record number of submissions. Over 5,000 abstracts will be published, and there'll be about 3,000 presentations, either in oral format or poster presentations. We have 200 dynamic sessions. Many of the discussants will be highlighting key takeaways and how we can translate action-oriented guidance to better treat our patients to build a better future. Our state-of-the-art science will include a Plenary Session. This will feature presentations as well as discussion of each of the presentations for clinical late-breaking abstracts. We have Clinical Science Symposia that I'm particularly excited about this year. These will feature key abstracts as well as discussions and a foundational talk around the subject. We're covering novel antibody-drug conjugate targets, turning “cold” tumors “hot” to include CAR T, as well as the future of cancer detection. There'll be rapid oral abstracts, case-based panels, and this will also feature interactive audience polling and case discussions. I also want to highlight the community connection opportunities. There will be 13 Communities of Practice that will be meeting on-site during ASCO, and there's also really a plethora of networking opportunities for trainees and early-career professionals, a Women's Networking Center, a patient advocate space, and I'm happy to report there will also be live music out on the terrace this year at ASCO. Dr. John Sweetenham: Well, that's going to be a really great addition. I have to say, I think this is always a special time of year because excitement starts to mount as the meeting gets closer and closer. And once the abstracts are out there, I certainly personally feel that the excitement builds. Talking of abstracts, let's dive into some of the key abstracts for this year's meeting. I'd like to start out by asking you about Abstract 505. This reports on 15-year outcomes for women with premenopausal hormone receptor-positive early breast cancer in the SOFT and TEXT trials. It assesses the benefits of adjuvant exemestane and ovarian function suppression or tamoxifen and ovarian function suppression. So, could you talk us through this and tell us what you think the key takeaways from this abstract are? Dr. Erika Hamilton: Absolutely. This is essentially the SOFT and TEXT trials. They are trials that we've been following for quite some time, evidenced by the 15-year outcome. And I think it really answers two very important questions for us regarding adjuvant endocrine therapy for patients that are facing hormone receptor-positive disease. The benefit of ovarian function suppression for one, and then second, the benefit of exemestane over tamoxifen, which is our SERM [selective estrogen receptor modulator]. So, in terms of the SOFT trial, when we talk about distance recurrence-free interval, which I really think is probably the most meaningful because secondary cancers, et cetera, are not really what we're getting at here. But in terms of distant recurrence-free interval, certainly with tamoxifen, using tamoxifen plus ovarian function suppression adds a little bit. But where we really get additional benefits are by moving to exemestane, an aromatase inhibitor with the ovarian function suppression. So, for example, in SOFT, for distant recurrence-free interval for patients that have received prior chemotherapy, the distance recurrence-free interval was 73.5% with tamoxifen, bumped up just a tiny bit to 73.8% with ovarian function suppression. But when we used both ovarian function suppression and switched to that aromatase inhibitor, we're now talking about 77.6%. It may seem like these are small numbers, but when we talk about an absolute benefit of 4%, these are the type of decisions that we decide whether to offer chemotherapy based on. So, really just optimizing endocrine therapy really can provide additional benefits for these patients. Just briefly, when we turn to TEXT, similarly, when we look at distance recurrence-free interval for our patients that are at highest risk and receive chemotherapy, tamoxifen and ovarian function suppression, 79%; 81% with exemestane and ovarian function suppression. And when we talk about our patients that did not receive chemotherapy, it increased from 91.6% up to 94.6%—very similar that 3% to 4% number. So, I think that this is just very important information when counseling our patients about the decisions that they're going to make for themselves in the adjuvant setting and how much we want to optimize endocrine therapy. Dr. John Sweetenham: Thanks so much for your insight into that. Dr. Erika Hamilton: Yeah, absolutely. So, let's turn to hematologic malignancies. Abstract 6506 reports exciting results on the new agent ziftomenib in relapsed/refractory NPM1-mutant acute myeloid leukemia. This is a phase 1b clinical activity study and safety results. This was the pivotal KOMET-001 study. And my question is, will this new agent fulfill an unmet need in this NPM1 space? Dr. John Sweetenham: Yeah, great question. And I think the answer is almost certainly ‘yes'. So, just as some brief background, NPM1 mutation is known to be a driver of leukemogenesis in around 30% of patients with AML, and it's a poor prognostic factor. And typically, about 50% of these patients will relapse within a year of their first-line therapy, and only around 10% of them will get a subsequent complete remission with salvage therapy. Menin inhibitors, which disrupt the interaction between menin and KMT2A, are known to be active in NPM1-mutated as well as in KMT2A-rearranged AML. And ziftomenib is a selective oral menin inhibitor, which in this study was evaluated at a dose of 600 mg once a day, as you mentioned, a phase 1b/2 study, which is multicenter and presented by Dr. Eunice Wang from Roswell Park. It's a relatively large study of 112 patients who were treated with this standard dose with relatively short median follow-up at this time. The median age was 69 years, and median prior therapies were two, but with a range of one to seven. And I think very importantly, 60% of these patients had previously been treated with venetoclax, and 23% of them had had a prior transplant. Looking at the results overall for this study, the overall response rate was 35%, which is actually quite impressive. Specifically for those patients in the phase 2 part of the study, around 23% achieved a CR [complete remission] or CRh [complete remission with partial hematologic recovery]. What's very interesting in my mind is that the response rates were comparable in venetoclax-naive and venetoclax-exposed patients. And the drug was very well tolerated, with only 3% of patients having to discontinue because of treatment-related adverse events. And I think the authors appropriately conclude that, first of all, the phase 2 primary endpoint in the study was met, and that ziftomenib achieved deep and durable responses in relapsed and refractory NPM1-mutated AML, regardless of prior venetoclax, with good tolerance of the drug. And so, I think putting all of this together, undoubtedly, these data do support the potential use of this agent as monotherapy and as a new option for those patients who have relapsed or refractory NPM1-mutated acute myeloid leukemia. So, let's move on a little bit more now and change the subject and change gears completely and talk about circulating tumor DNA [ctDNA]. This has been a hot topic over a number of years now, and at this year's meeting, there are quite a few impactful studies on the use of ctDNA. We have time to focus on just one of these, and I wanted to get your thoughts on Abstract 4503. This is from the NIAGARA trial, which looks at ctDNA in patients with muscle-invasive bladder cancer who receive perioperative durvalumab. Could you tell us a little bit about this study? Dr. Erika Hamilton: So, this was the phase 3 NIAGARA trial, and this is literally looking for patients with muscle-invasive bladder cancer that are cisplatin-eligible, and the addition of durvalumab to neoadjuvant chemotherapy. So here, this is a planned exploratory analysis of ctDNA and the association with clinical outcomes from NIAGARA. So, this is really the type of study that helps us determine which of our patients are more likely to have a good outcome and which of our patients are more likely not to. There were 1,000 randomized patients in this study, and 462 comprised the biomarker-evaluable population. There were about half in the control arm and half in the durvalumab arm. And overall, the ctDNA-positive rate at baseline was about 57%, or a little over half, and that had decreased to about 22% after neoadjuvant treatment. ctDNA clearance rates from baseline to pre-radical cystectomy was about 41% among those with durvalumab and 31% among those in control. And the non-pCR rate was 97% among patients with pre-cystectomy ctDNA-positive status. So, this really gives us some information about predicting who is going to have better outcomes here. We did see a disease-free survival benefit with perioperative durvalumab, and this was observed in post-cystectomy ctDNA-positive as well as the ctDNA-negative groups. Shifting gears now to GI cancer, Abstract 3506 is a long-term safety and efficacy study of sotorasib plus panitumumab and FOLFIRI for previously treated KRAS G12C-mutated metastatic colorectal cancer. And this is the CodeBreaK-101 study. What are your thoughts on this study? Dr. John Sweetenham: Yeah, thanks. A very interesting study, and this abstract builds upon the phase 3 CodeBreaK-300 trial, which I think has just been published in the Journal of Clinical Oncology. This showed that the combination of sotorasib and panitumumab improved clinical outcomes in patients with chemorefractory KRAS G12C-mutated metastatic colorectal cancer. The current abstract, as you mentioned, reports the CodeBreaK-101 trial. And this was a phase 1b trial where FOLFIRI therapy was added to sotorasib and panitumumab in previously treated patients with KRAS G12C-mutated metastatic colorectal cancer. The abstract reports the overall and progression-free survival results, as well as some updated safety and response data. So, in this study, patients with this particular mutation who had received at least one prior systemic treatment but were KRAS G12C inhibitor-naive were enrolled into an expansion cohort of the CodeBreaK-101 protocol. And these patients received what apparently now recommended as the standard phase 2 dose of sotorasib of 960 mg daily, plus panitumumab and a standard dose of FOLFIRI. And the primary endpoint of the study was safety, and secondary endpoints included confirmed response, overall response, and progression-free survival, as assessed by the investigator. And by November of last year, 40 patients had been enrolled into this study. Common treatment-related adverse events were cutaneous; some patients developed neutropenia, and stomatitis was fairly widespread. Discontinuation of sotorasib because of adverse events was only seen in 1% of patients, although patients did have to discontinue because of toxicity from some of the other agents in the combination. Looking at the results of this study, the updated objective response rate was 57.5%, and the disease control rate was estimated at 92%, going on 93%, with a median time to response of 1.6 months and a median response duration of 6 months. After a median follow-up of 29.2 months, the median progression-free survival was 8.2 months, and the overall survival 17.9 months. So, the authors have concluded that this combination, including sotorasib, panitumumab, and FOLFIRI, does appear to show quite promising long-term efficacy in pretreated patients with this specific mutation. The ongoing phase 3 study they mentioned, CodeBreaK-301, is aiming to evaluate this combination against the standard of care in the first-line setting for patients with KRAS G12C-mutated colorectal cancer. So, promising results, and we'd be very interested to see how this particular combination performs in the frontline. Dr. Erika Hamilton: Fantastic. Thanks so much for sharing that. Let's shift gears again and really talk about digital technology. I feel that we're all going to have to get much better with this, and really, there are a lot of promises for our patients coming here. There are a lot of abstracts at ASCO that are focusing on innovations in digital technology, including a really interesting psychosocial digital application for caregivers of patients that are undergoing hematopoietic stem cell transplantation. Can you tell us a little bit about this? It's Abstract 11000. Dr. John Sweetenham: Yeah, absolutely. This abstract certainly caught my eye, and I think it's intriguing for a number of reasons, partly because it's app-based, and partly also because it specifically addresses caregiver burden and caregiver needs in the oncology setting, which I think is especially important. And although the context, the clinical context of this study, is hematopoietic stem cell transplantation, I think it has potential applications way beyond that. We all know that caregivers of patients undergoing stem cell transplantation have significant quality-of-life struggles. They are well-documented to have significant psychological and emotional strain before, during, and after stem cell transplantation. And this abstract describes an application called BMT-CARE, which is aimed at improving caregivers' quality of life, caregiver burden, mood symptoms, and coping skills, and so on. So, this was a single-center, randomized trial from MGH [Massachusetts General Hospital] of this app for stem cell transplant caregivers, compared with usual care in those individuals. And the eligible patients, or eligible individuals, were adults caring for patients with heme malignancy undergoing either an autologous or an allogeneic stem cell transplant. Patients were randomly assigned either to use the app or for usual care. And the app itself—and I think it'll be interesting to actually see this at the meeting and visualize it and see how user-friendly and so on it is—but it comprises five modules, which integrate psychoeducation, behavior change, stress management, and they're delivered through a kind of interactive platform of educational games and videos. And then participants were self-reporting at baseline and then 60 days after transplant. So, around 125 patients were enrolled in this study, of around 174 who were initially approached. So, just over 70% uptake from caregivers, which is, I think, relatively high, and evenly distributed between the two randomized arms. And the majority of the participants were spouses. And at 60 days post-stem cell transplant, the intervention participants reported a better quality of life compared with those who received usual care. If you break this down a little bit more, these participants reported lower caregiving burden, lower incidence of depression, fewer PTSD symptoms, and overall better coping skills. So, the authors conclude that this particular app, a digital health intervention, led to pretty substantial improvements in quality of life for these caregivers. So, intriguing. As I said, it'll be particularly interesting to see how this thing looks during the meeting. But if these kind of results can be reproduced, I think this sort of application has potential uses way beyond the stem cell transplant setting. Dr. Erika Hamilton: Yeah, I find that just so fascinating and very needed. I think that the caregiving role is often underestimated in how important that is for the patient and the whole family, and really giving our caregivers more tools in their toolbox certainly is quite helpful. Dr. John Sweetenham: Absolutely. Well, the meeting is getting closer, and as I mentioned earlier, I think anticipation is mounting. And I wanted to say thanks so much to you for chatting with me today about some of the interesting advances in oncology that we're going to see at this year's meeting. There is a great deal more to come. Our listeners can access links to the studies we've discussed today in the transcript of this episode. I'm also looking forward, Dr. Hamilton, to having you back on the podcast after the Annual Meeting to dive into some of the late-breaking abstracts and some of the other key science that's captured the headlines this year. So, thanks once again for joining me today. Dr. Erika Hamilton: Thanks so much for having me. Pleasure. Dr. John Sweetenham: And thank you to our listeners for joining us today. Be sure to catch my “Top Takeaways from ASCO25.” These are short episodes that will drop each day of the meeting at 5:30 p.m. Eastern Time. So, subscribe to the ASCO Daily News Podcast wherever you prefer to listen, and join me for concise analyses of the meeting's key abstracts.   Disclaimer: The purpose of this podcast is to educate and to inform. This is not a substitute for professional medical care and is not intended for use in the diagnosis or treatment of individual conditions. Guests on this podcast express their own opinions, experience, and conclusions. Guest statements on the podcast do not express the opinions of ASCO. The mention of any product, service, organization, activity, or therapy should not be construed as an ASCO endorsement.   More on today's speakers: Dr. John Sweetenham   Dr. Erika Hamilton @erikahamilton9   Follow ASCO on social media:  @ASCO on Twitter  ASCO on Bluesky  ASCO on Facebook   ASCO on LinkedIn     Disclosures:     Dr. John Sweetenham:     No relationships to disclose  Dr. Erika Hamilton: Consulting or Advisory Role (Inst): Pfizer, Genentech/Roche, Lilly, Daiichi Sankyo, Mersana, AstraZeneca, Novartis, Ellipses Pharma, Olema Pharmaceuticals, Stemline Therapeutics, Tubulis, Verascity Science, Theratechnologies, Accutar Biotechnology, Entos, Fosun Pharma, Gilead Sciences, Jazz Pharmaceuticals, Medical Pharma Services, Hosun Pharma, Zentalis Pharmaceuticals, Jefferies, Tempus Labs, Arvinas, Circle Pharma, Janssen, Johnson and Johnson   Research Funding (Inst): AstraZeneca, Hutchison MediPharma, OncoMed, MedImmune, Stem CentRx, Genentech/Roche, Curis, Verastem, Zymeworks, Syndax, Lycera, Rgenix, Novartis, Millenium, TapImmune, Inc., Lilly, Pfizer, Lilly, Pfizer, Tesaro, Boehringer Ingelheim, H3 Biomedicine, Radius Health, Acerta Pharma, Macrogenics, Abbvie, Immunomedics, Fujifilm, eFFECTOR Therapeutics, Merus, Nucana, Regeneron, Leap Therapeutics, Taiho Pharmaceuticals, EMD Serono, Daiichi Sankyo, ArQule, Syros Pharmaceuticals, Clovis Oncology, CytomX Therapeutics, InventisBio, Deciphera, Sermonix Pharmaceuticals, Zenith Epigentics, Arvinas, Harpoon, Black Diamond, Orinove, Molecular Templates, Seattle Genetics, Compugen, GI Therapeutics, Karyopharm Therapeutics, Dana-Farber Cancer Hospital, Shattuck Labs, PharmaMar, Olema Pharmaceuticals, Immunogen, Plexxikon, Amgen, Akesobio Australia, ADC Therapeutics, AtlasMedx, Aravive, Ellipses Pharma, Incyte, MabSpace Biosciences, ORIC Pharmaceuticals, Pieris Pharmaceuticals, Pieris Pharmaceuticals, Pionyr, Repetoire Immune Medicines, Treadwell Therapeutics, Accutar Biotech, Artios, Bliss Biopharmaceutical, Cascadian Therapeutics, Dantari, Duality Biologics, Elucida Oncology, Infinity Pharmaceuticals, Relay Therapeutics, Tolmar, Torque, BeiGene, Context Therapeutics, K-Group Beta, Kind Pharmaceuticals, Loxo Oncology, Oncothyreon, Orum Therapeutics, Prelude Therapeutics, Profound Bio, Cullinan Oncology, Bristol-Myers Squib, Eisai, Fochon Pharmaceuticals, Gilead Sciences, Inspirna, Myriad Genetics, Silverback Therapeutics, Stemline Therapeutics

Iglesia Gracia Redentora
Mateo 20:1-16

Iglesia Gracia Redentora

Play Episode Listen Later May 20, 2025 24:43


Sermón: Mateo 20:1-16 Serie: Reinos Enfrentados

La Vida Que Quiero
¿Te sientes solo? Cómo superar la soledad

La Vida Que Quiero

Play Episode Listen Later May 19, 2025 46:34


La soledad no siempre se nota, pero pesa. En este episodio hablamos de los distintos tipos de soledad —emocional, social, circunstancial y elegida— y de cómo empezar a salir del aislamiento interno. Verás por qué a veces te sientes solo incluso acompañado y qué pasos puedes dar para construir vínculos más auténticos, empezando por ti. ⭐ Accede GRATIS aquí a mi curso: Ser Más Feliz.

Iglesia Presbiteriana Westminster - EPC
Lo Más Valioso - Sermón 06 de abril de 2025

Iglesia Presbiteriana Westminster - EPC

Play Episode Listen Later May 19, 2025 28:00


Juan 12:1-8   Support the show

Un Mensaje a la Conciencia
«Porque no logré ser médica»

Un Mensaje a la Conciencia

Play Episode Listen Later May 17, 2025 4:01


En este mensaje tratamos el siguiente caso de una mujer que «descargó su conciencia» de manera anónima en nuestro sitio www.conciencia.net, autorizándonos a que la citáramos: «Soy una joven de veinticuatro años y vivo con mis padres.... Mi madre... se enojó [mucho porque no logré] ser médica, y me compara con mi hermana menor, quien pudo completar sus estudios antes que yo. »He caído en una depresión por no hacerla feliz con mi carrera y mi vida.... Yo trato de dirigirme a ella con respeto... pero ella no se siente honrada. »Tengo trabajo y sigo asistiendo a la escuela. Le he dicho que quiero mudarme para independizarme, pero ella lo toma a mal y me dice que no me mude sino hasta que me case.» Este es el consejo que le dio mi esposa: «Estimada amiga: »Comprendemos por qué se siente descorazonada. Por lo general, cuando alguna persona a quien amamos está decepcionada de nosotros, eso hace que nos sintamos mal. Esa sensación de deficiencia nos lleva entonces a tener pensamientos recurrentes que ponen en tela de juicio todo lo que creemos acerca de quiénes somos. Y cuando dudamos de nosotros mismos, es muy difícil estar motivados acerca del futuro. »... Es posible que [su mamá] la presione a usted debido a que ella nunca logró lo que quiso en su propia vida y, como resultado, quiere que, a diferencia de ella, usted no tenga que arrepentirse de nada a lo largo de su vida. O tal vez crea que le corresponde a ella como mamá suya ejercer presión cuando usted no obtiene los logros que ella piensa que usted es capaz de alcanzar. »Los padres que tienen hijos adultos deben pasar de ser proveedores, protectores y maestros, a ser amigos cercanos que los animan. Sin embargo, algunos padres nunca llegan a comprender que ese cambio en la relación es saludable. Y otros padres dejan que influyan en ellos su propia inseguridad y personalidad dominante, o su propia inmadurez y egoísmo. »Su mamá concibe que ella la protege al mantenerla en casa hasta que usted se case. Pero ¿qué tal si usted decide no casarse? ... Los hijos adultos que siguen viviendo con los padres a veces descubren que con el paso de los años se vuelve cada vez más difícil independizarse. »Si usted cuenta con los recursos económicos necesarios para vivir por su propia cuenta, entonces creemos que el mudarse e independizarse es una opción aceptable. No obstante, esa decisión la debe tomar conforme a su contexto cultural, ya que algunas culturas no permiten que las mujeres vivan por su propia cuenta. »Usted dice que, a pesar de dirigirse a su mamá con respeto, ella no se siente honrada por usted. Ya que uno de los Diez Mandamientos es honrar a padre y madre, le aconsejamos que siempre honre a su mamá. Sin embargo, honrarla no significa obedecerla o estar de acuerdo con ella en todas las cosas. Ni significa que usted esté obligada a ejercer la profesión que ella desea que practique.» Con eso termina lo que recomienda Linda, mi esposa. El consejo completo puede leerse con sólo ingresar en el sitio www.conciencia.net y pulsar la pestaña que dice: «Casos», y luego buscar el Caso 723. Carlos ReyUn Mensaje a la Concienciawww.conciencia.net

Iglesia Adventista del Séptimo Día, Keene, Texas
DEVOCIONAL | 2025.05.16 | "A solas con Jesús" | "Más poderoso que un sermón"

Iglesia Adventista del Séptimo Día, Keene, Texas

Play Episode Listen Later May 16, 2025 5:21


"Este devocional es una iniciativa de la Iglesia Adventista del Séptimo Día en Keene, Texas, diseñado para fortalecer tu espíritu y renovar tu fe cada día. A través de reflexiones sencillas pero profundas, encontrarás ánimo para enfrentar los retos diarios con confianza y esperanza. Cada mensaje te invita a recordar las promesas de Dios y a disfrutar de momentos íntimos y transformadores “A solas con Jesús”. Directora: Nancy Rodríguez Referencia: ""A solas con Jesús"" (1998) | Pr. Alejandro Bullón Lector: Jackie Martínez Redes Sociales: @AdventistaDeKeene Website: https://www.keenehsda.org Créditos de la Música: ""Emotional"" | Autor: AlexBird ¡Dios le bendiga!

Podcasts do Portal Deviante
Ser Mãe (Miçangas #230)

Podcasts do Portal Deviante

Play Episode Listen Later May 15, 2025 53:05


Nesta semana, recebemos a Senhora Tick, a Lívia! Conversamos sobre como foi ser mãe para ela e dividimos outras histórias de maternidade. SEJA NOSSO PADRINHO AJUDE A NASCER UM MIÇANGAS...

Música Cristiana (Gratis)
Clip del Sermón «Navegando Mar Adentro», por Geraldo Belgrove @ibc_ebenezer

Música Cristiana (Gratis)

Play Episode Listen Later May 12, 2025 0:35


Clip del Sermón «Navegando Mar Adentro», por Geraldo Belgrove @ibc_ebenezer by #HappyThanksgiving #Thanksgiving #navidad2024 #navidad #merry #viernesnegro #regalos #gif #christmas #merrychristmas #regalos #diciembre #love #merrychristmas2024Conviértete en un seguidor de este podcast: https://www.spreaker.com/podcast/radio-ebenezer-rd-emisora-cristiana--3279340/support.

El Mañanero Radio
Sandra aclara que su vida privada será más oculta - Trapitos al sol

El Mañanero Radio

Play Episode Listen Later May 12, 2025 10:52