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On this episode, host Pete Moore dives into the cutting-edge world of regenerative medicine and longevity with guests Howard Leonhardt, founder of Leonhardt Ventures and Lionheart Health, and Scott Hoots, an expert in health and wellness franchising. Leonhardt is an innovative medical entrepreneur whose journey started in 1982 with the founding of Leonhardt Ventures, the parent of Lionheart Health and Lionheart Longevity and Wellness. Over the decades, Leonhardt has pioneered groundbreaking medical inventions—most notably in combining stem cells with bioelectronic stimulation to assist in regenerating parts of the heart muscle. Since launching this research in 1988, Leonhardt has raised and invested more than $150 million, driving clinical trials in collaboration with over 50 leading research centers worldwide, including the Mayo Clinic and Cleveland Clinic. To date, over 600,000 patients have been treated using technologies developed by Leonhardt, whose inventions have generated more than $1.7 billion in annual revenues for their acquirers. With regards to turning back the clock on aging, Howard states, "Lionheart Health technologies basically, in short, helps in regenerating your body twenty years, and that includes skin, hair, sexual health, and joint health. That is our goal for our clinics. That is our goal for our products, and we have 500 patent claims protecting that very unique technology." Key themes discussed Longevity and regenerative health technologies to help reverse aging. Lionheart Health's patented EMS suits and stimulators. Business models: Licensing, franchising, and commercialization strategies. Clinical results and patented protein expression stimulation. Integration opportunities for med spas and fitness operators. Investment options in Lionheart Health and related ventures. Challenges of competing with traditional pharma solutions. A few key takeaways: 1. Lionheart Health's Unique Regenerative Technology: Howard Leonhardt's team has developed technology that combines stem cells and bioelectric stimulation to aid in regenerate tissue and reverse aging signs. Their EMS suits and stimulators are patented to specifically induce the production of proteins—like klotho and follistatin—that are associated with longevity and age reversal. 2. Clinical Results and Diverse Applications: Lionheart Health's approaches are already well-tested: Over 600,000 patients have been treated with related technologies, and the team has run FDA trials and partnerships with top institutions (Mayo Clinic, Cleveland Clinic, etc.) Applications extend beyond muscle and joint health to skin, hair, and sexual health—essentially offering full-body rejuvenation. 3. Business Model-Licensing and Franchising: The team is rolling out Lionheart Health through both licensing and franchising. Existing med spas, EMS studios, or wellness clinics can license these suits and stimulators, differentiating their business and adding high-value longevity services. Franchise opportunities will open up more broadly in 2025, with flexible models to suit different markets. 4. Revenue Potential and Clinic Setup: Licensing starts at $40,000 for a dedicated suite, with ongoing royalties. The professional EMS suits for clinics range in cost; most studios operate on a membership basis, with clients attending regular sessions (e.g., twice weekly for 4-12 weeks.) The company has plans for significant expansion, targeting over 100 licensed/franchised locations in the coming years. 5. Vision-Competing with Traditional Solutions: Lionheart is directly challenging “big pharma” and traditional approaches (like pill-based ED solutions), offering regenerative, non-pharmaceutical interventions. They're participating in major longevity challenges (such as the $101 million XPRIZE for healthspan), aiming to drastically improve muscle, brain, and immune health—potentially reversing aging by 20 years for participants. Resources: Howard Leonhardt: https://www.linkedin.com/in/howard-leonhardt-6694185 Leonhardt Health: https://lionhearthealthstim.com Leonhardt Ventures: https://leonhardtventures.com Prospect Wizard: http://www.theprospectwizard.com Promotion Vault: http://www.promotionvault.com HigherDose: http://www.higherdose.com
Summary This The Future of Dermatology Podcast focuses on recent advancements in the treatment of vitiligo, particularly highlighting the role of Afamelanotide in clinical trials. Dr. Kamangar includes insights from the SF Derm 2024 Annual Meeting, the mechanisms of vitiligo, and the potential of Afamelanotide to aid in repigmentation without affecting the immune system. Clinical trial results and patient outcomes are also discussed, emphasizing the importance of this treatment for patients with darker skin types. Takeaways Vitiligo treatments have traditionally focused on the immune system. Afamelanotide aims to boost repigmentation without immune suppression. The study is a phase three trial comparing Afamelanotide with narrowband UVB. Initial results show promise for Fitzpatrick skin types four to six. The treatment is suitable for adolescents and adults aged 12 and up. Photos from trials indicate significant repigmentation in patients. - Afamelanotide has a good safety profile based on previous treatments. The drug is being studied for its broader dermatological applications. - There are concerns about unregulated versions of Afamelanotide in the market. Awareness of Afamelanotide is crucial for dermatologists. Chapters 00:00 - Introduction to the Future of Dermatology Podcast 01:20 - Exploring Vitiligo Treatments and Research 03:10 - Afamelanotide: A New Hope for Repigmentation 05:37 - Clinical Results and Implications of Afamelanotide
Historically, ACL repair resulted in poor outcomes and this procedure fell out of favor while ACL reconstruction became the gold-standard surgical approach for a torn ACL. Recently, thanks in part to the advent of more modern techniques, ACL repair has regained interest in the Sports Medicine community as a potentially viable option in certain situations that may provide advantages in comparison to ACL reconstruction. To this point, the literature comparing these two surgeries with modern techniques has been heterogenous in terms of quality and design, and results have been mixed. Drs. Kyle Kunze, MD and Benedict Nwachukwu, MD, MBA and their team from Hospital of Special Surgery (HSS) bring us this systematic review and meta-analysis to cull the best literature available. Their findings indicate that, while ACL repair may have an evolving role in our toolbox, its failure rate remains higher than that of ACL reconstruction and thus should be approached with caution.
In this episode we're joined by Justin Zenanko, CEO and co-founder of SynerFuse to discuss groundbreaking technique combining spinal fusion and direct nerve stimulation to treat chronic low back pain, aiming to eliminate the need for postoperative opioids. Justin delves into the inspiration behind the technology, its clinical results, and the company's approach to quality and regulatory management. He also provides insights on raising funds in a competitive market and the potential future applications of SynerFuse's technology.Justin's BioJustin Zenanko, CPA, MDiv, is the president, CEO, and co-founder of SynerFuse, Inc., a Minnesota-based company innovating the spine industry with its integrated approach which combines spinal fusion and direct nerve stimulation to address the chronic low back pain that is unaddressed in about 40% of the 500,000 traditional spinal fusion surgeries that take place annually in the US alone. The SynerFuse approach aims to eliminate the post-surgical need for addictive opioids. Link to SynerFuse website: https://www.synerfuse.com/00:00 Introduction and Welcome00:41 Meet Justin Zinenko: From CPA to MedTech Innovator03:16 The Birth of SynerFuse: Combining Spinal Fusion with Nerve Stimulation05:29 Clinical Results and Patient Success Stories08:46 Quality and Regulatory Approaches in MedTech10:29 Future Applications and Innovations14:59 Advice for Aspiring Entrepreneurs17:51 Fun Insights and Closing Remarks Qualio website:https://www.qualio.com/ Previous episodes:https://www.qualio.com/from-lab-to-launch-podcast Apply to be on the show:https://forms.gle/uUH2YtCFxJHrVGeL8 Music by keldez
Ready to bring clinical-grade micro-infusion to your home?In this episode, Amber sits down with with skincare maven, holistic health coach, and YouTube sensation Chris Gibson, to talk about the Qure micro-infusion system. Hear why micro-infusion has become a cornerstone of Chris's beauty regimen and get ready to be blown away when he reveals his age! You'll learn about::Micro-Infusion Precision vs. Derma Rollers: Understand the distinctions between micro-infusion systems and derma rollers, emphasizing the Qure system's precision and controlled infusion over the potential risks and imprecision of rollers.Scientific Insights: Hear about the science behind micro-infusion, discovering how this innovative device delivers serums to activate collagen production, thereby enhancing skin texture and vitality.Step-by-Step Demonstration: Get a guided tour through the correct usage of the Qure system, and how to integrate it seamlessly into your beauty routine.Beta Glucans vs. Hyaluronic Acid: Delve into the benefits of beta-glucans for skin hydration, contrasting them with hyaluronic acid and emphasizing beta glucans' ability to deeply hydrate skin without external moisture reliance.Skincare Strategies and Age Consideration: Gain insights into skincare timing and the ideal age to initiate certain skincare treatments, while advocating for proactive approaches to maintain skin youthfulness without solely relying on procedures like Botox.Qure Micro-Infusion System Recommendation: Discover why Chris advocates for the Qure Micro-Infusion System as a cost-effective at-home alternative, highlighting its affordability and effectiveness in achieving radiant skin.DISCOUNT: Use code ARTBEAUTY for 10% off
PDS Biotechnology (PDSB) stock price is up over 61% this past year. PDS Biotechnology director, president, and CEO, Dr. Frank Bedu, weighs in on the latest trial results that indicated 100% clinical response for treatment of cervical cancer patients with large tumors using a combination of PDS101 with standard-of-care chemoradiotherapy. All patients had a tumor shrinkage of 60% or greater.
Dr. Lora Bean gives an overview of phenotypically-driven clinical results in this episode of DNA Today!Dr. Lora Bean is a clinical molecular geneticist who currently serves as the Senior Director of Quality Assurance at PerkinElmer Genomics. Dr. Bean has expertise in traditional clinical molecular testing as well as newer techniques such as next generation exome and genome sequencing. She has served as a molecular editor for GeneReviews and as a member of the American College of Medical Genetics Laboratory QA / QC Committee, an item writer for the ABMGG, and is currently a laboratory inspector and a Biochemical and Molecular Genetics Committee member for the College of American Pathologists. Previously, she served as an Associate Professor in the Department of Human Genetics and Senior Director and Regulatory Director of the EGL Genetics (formerly Emory Genetics Laboratory) Molecular Diagnostic Laboratory. Dr. Bean earned her PhD in the Department of Human Genetics at Case Western Reserve University and completed a postdoctoral fellowship at Emory University. She is board-certified by the American Board of Medical Genetics and Genomics and a fellow of the American College of Medical Genetics. On This Episode We Discuss:Differences between gene panels, exome, and genome sequencing Adapting workflows from exome to genome utilizing existing frameworksAdvantages of different types of testingLimiting the floodgates of variants that inevitably come with whole genome sequencingHelpful information for providers to include with specimens to guide the laboratory when the data are analyzedThe role of phenotypic data specifically in classification of sequence variantsDeep intronic variantsKira was off by one, but Dr. Bean was right, ACMG has 73 genes on the list for reporting of secondary findings in clinical exome and genome sequencing: a policy statement of the American College of Medical Genetics and Genomics (ACMG). If you found the topics that we discussed on this episode interesting, check out this recorded presentation from Dr. Bean entitled, “Why Bigger Isn't Only VOUSier.”Learn more about phenotypically-driven clinical results at PerkinElmerGenomics.com and follow them on Twitter, Facebook, and LinkedIn. Stay tuned for the next new episode of DNA Today on October 21st, 2022! New episodes are released on Fridays. In the meantime, you can binge over 205 other episodes on Apple Podcasts, Spotify, streaming on the website, or any other podcast player by searching, “DNA Today”. Episodes since 2021 are also recorded with video which you can watch on our YouTube channel. DNA Today is hosted and produced by Kira Dineen. Our social media lead is Corinne Merlino. Our video lead is Amanda Andreoli. See what else we are up to on Twitter, Instagram, Facebook, YouTube and our website, DNAToday.com. Questions/inquiries can be sent to info@DNAtoday.com. When Willow was diagnosed with Multiple Sulfatase Deficiency (MSD), her mother, Amber was told to love and care for Willow but that there was no cure for this terrible fatal condition. Amber set out to find and fund the cure for MSD. That's when she started the United Multiple Sulfatase Deficiency Foundation. She shares this personal experience on Episode 205 of DNA Today including how this affected her family and the relationships she has built with other families in the MSD community. (SPONSORED)TrakGene has designed a genetics electronic health record. Here's what it features: pedigrees, demographic data, genetics information, risk tools, and sophisticated reporting, all within a clinician designed workflow. It integrates with other clinical genetic software, databases, and hospital information systems to maintain accurate patient records.Go check it out at TrakGene.com. And keep your eye out for our full episode interviews with TrakGene coming soon to DNA Today. (SPONSORED)
Drs Madhukar Trivedi and Bradley Gaynes discuss the benefits of measurement-based care and how best to deliver it for patients with major depressive disorder. Relevant disclosures can be found with the episode show notes on Medscape (https://www.medscape.com/viewarticle/968559). The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals. Resources Patient Health Questionnaire-9 (PHQ-9) https://reference.medscape.com/calculator/271/patient-health-questionnaire-9-phq-9 Clinical Results for Patients With Major Depressive Disorder in the Texas Medication Algorithm Project https://jamanetwork.com/journals/jamapsychiatry/fullarticle/482026 Depression, IV: STAR*D Treatment Trial for Depression https://ajp.psychiatryonline.org/doi/full/10.1176/appi.ajp.160.2.237#F1 APA Clinical Practice Guideline for the Treatment of Depression Across Three Age Cohorts https://www.apa.org/depression-guideline/guideline.pdf The Efficacy of Measurement-Based Care for Depressive Disorders: Systematic Review and Meta-analysis of Randomized Controlled Trials https://www.psychiatrist.com/jcp/depression/measurement-based-care-depression/ Final Recommendation Statement – Depression in Adults: Screening https://www.uspreventiveservicestaskforce.org/uspstf/document/RecommendationStatementFinal/depression-in-adults-screening Nonpharmacologic Versus Pharmacologic Treatment of Adult Patients With Major Depressive Disorder: A Clinical Practice Guideline From the American College of Physicians https://www.acpjournals.org/doi/10.7326/M15-2570 The 16-Item Quick Inventory of Depressive Symptomatology (QIDS), Clinician Rating (QIDS-C), and Self-report (QIDS-SR): A Psychometric Evaluation in Patients With Chronic Major Depression https://www.biologicalpsychiatryjournal.com/article/S0006-3223(02)01866-8/fulltext Hamilton Depression Rating Scale (HAM-D or HDRS) https://reference.medscape.com/calculator/146/hamilton-depression-rating-scale-ham-d-or-hdrs Montgomery and Åsberg Depression Rating Scale (MADRS) https://www.apa.org/depression-guideline/montgomery-asberg-scale.pdf
Madhukar Trivedi, MD, and Manish Jha, MD, MBBS, review the evidence on the efficacy of esketamine and ketamine as a treatment for major depressive disorder. Relevant disclosures can be found with the episode show notes on Medscape.com (https://www.medscape.com/viewarticle/968556). The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals. Resources Symptom Clusters as Predictors of Late Response to Antidepressant Treatment https://www.psychiatrist.com/jcp/depression/symptom-clusters-predictors-late-response-antidepressant/ Intranasal Esketamine https://www.janssenlabels.com/package-insert/product-monograph/prescribing-information/SPRAVATO-pi.pdf Sequenced Treatment Alternatives to Relieve Depression (STAR*D) Study https://www.nimh.nih.gov/funding/clinical-research/practical/stard Clinical Results for Patients With Major Depressive Disorder in the Texas Medication Algorithm Project https://jamanetwork.com/journals/jamapsychiatry/fullarticle/482026 Efficacy and Safety of Olanzapine/Fluoxetine Combination vs Fluoxetine Monotherapy Following Successful Combination Therapy of Treatment-Resistant Major Depressive Disorder https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207330/ Esketamine Nasal Spray for Rapid Reduction of Depressive Symptoms in Patients With Major Depressive Disorder Who Have Active Suicide Ideation With Intent: Results of a Phase 3, Double-Blind, Randomized Study (ASPIRE II) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7816667/ Esketamine Nasal Spray for the Rapid Reduction of Depressive Symptoms in Major Depressive Disorder With Acute Suicidal Ideation or Behavior https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8407443/ Ketamine Versus Midazolam for Recurrence of Suicidality in Adolescents https://clinicaltrials.gov/ct2/show/NCT04592809 Youth Depression and Suicide Research Network (YDSRN) https://clinicaltrials.gov/ct2/show/NCT04572321 The Neurobiology of Depression, Ketamine and Rapid-Acting Antidepressants: Is it Glutamate Inhibition or Activation? https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6165688/ Effect of Ketamine on Limbic GABA and Glutamate: A Human In Vivo Multivoxel Magnetic Resonance Spectroscopy Study https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7507577/ Identifying Novel Mechanisms and Treatment Targets for Irritability and Aggression in Psychiatric Disorders https://www.nature.com/articles/s41386-021-01166-4 Ketamine Versus Midazolam for Recurrence of Suicidality in Adolescents https://clinicaltrials.gov/ct2/show/NCT04592809 Ketamine for Depression: An Update https://www.biologicalpsychiatryjournal.com/article/S0006-3223(16)32579-3/fulltext MDMA-Assisted Therapy for Severe PTSD: A Randomized, Double-Blind, Placebo-Controlled Phase 3 Study https://www.nature.com/articles/s41591-021-01336-3 Trial of Psilocybin versus Escitalopram for Depression https://www.nejm.org/doi/full/10.1056/NEJMoa2032994 The Clinical Pharmacology and Potential Therapeutic Applications of 5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT) https://onlinelibrary.wiley.com/doi/10.1111/jnc.15587
Drs Arner and Zaffanini discuss A comparison between Polyurethane and Collagen Meniscal Scaffold for Partial Meniscal Defects: Similar positive clinical results at a mean of 10-Years of Follow-up.
Clinical Results of Topography-based Customized Ablations in Highly Aberrated Eyes and Keratoconus/Ectasia with Cross-linkingOn the laser's edge – breaking taboos! Dr Aanchal Gupta is the Director of Training for the South Australian Training network and a Senior Clinical lecturer at the University of Adelaide. She reviews Clinical results of topography-based customized ablations in highly aberrated eyes and keratoconus/ectasia with cross-linking, the article as written by her fellowship mentors that started her interest in refractive surgery. The results demonstrate how laser platforms can go beyond routine vision correction. Irregular astigmatism, keratoconus patients and those with decentred ablations can be successfully treated with laser. This allows patients to avoid rigid contact lenses, transplants or glasses with suboptimal vision. Do the results last? What are the long-term outcomes? What can go wrong? Aanchal explores… View article here
Vadim Alexandre, Head of Healthcare at SP Angel discusses Spectral MD's #SMD Clinical Results and DFU Application. About Spectral MD Using its DeepView® Wound Imaging Solution, an internally developed AI technology and multispectral imaging solution that has received FDA Breakthrough Designation for the burn indication, Spectral MD is able to distinguish between non-healing and healing human tissue invisible to the naked eye. Spectral MD currently is able to provide 'Day One' healing assessments for burn wounds and diabetic foot ulcers with other applications being explored.
YOUTH® Health Chat – Learn more about how Shaklee scientists developed YOUTH to deliver Clinical Results without Compromise™. Formulated by harnessing the power of botanicals, providing essential nutrients and vitamins to nourish skin all formulated with advanced technologies to provide clinically proven clean beauty in four simple steps.
Shaklee TV: Videos from Shaklee Corporation, the #1 Natural Nutrition Company in the United States.
YOUTH® Health Chat – Learn more about how Shaklee scientists developed YOUTH to deliver Clinical Results without Compromise™. Formulated by harnessing the power of botanicals, providing essential nutrients and vitamins to nourish skin all formulated with advanced technologies to provide clinically proven clean beauty in four simple steps.
If you have ever been to San Francisco because you need help repairing from something no one else could figure out, then you are no doubt there to see Marc Weil. For over 40 years Marc has used his exceptional skills in natural medicine to heal or reverse cancer, scleroderma, pain of all types, stroke recovery and scar tissue repair with nutrition, and devices for diagnostics and treatment that come straight out of a sci-fi movie. He is my mentor. He is my friend. He is going to give you more to learn about and use than you could possibly imagine was possible!Oh, and just in case you have a need to detox (who doesn't?!), THIS is the episode to pay attention to for the healthiest and most effective way to go about clearing toxins, stagnant lymph, and cellular debris from your body.Marc is the real deal, and I am honored to talk with hm in this episode of [un]common medicine. You can connect with him directly for your healthcare needs through his websiteCoreCareCenter.com
Today's episode is covering and extremely sought after topic: DNP. Justin will take you into his understanding and research on DNP and how it reacts within the body. What studies have shown, what it can be used for, what it shouldn't be used for, how it can be abused and how it can be positive. It's one of the most interesting PEDs we've talked about and this one is heavy. Make sure to get out your notepads and listen a few times through. Remember, do your research thoroughly, don't let ignorance take over. At the bottom of the show notes are links to studies and articles covering DNP that we reference in the podcast. This podcast is brought to you by Revive and RAW Nutrition. Use code Mihaly15 for Revive and Mihaly for RAW. Follow the podcast on Instagram for daily clips from your favorite episodes! @JMIHALYFIT @SCOTTSIMNZ DISCLAIMER: The content of this episode is for entertainment purposes only. It is not intended to substitute for professional medical advice, diagnosis or treatment. Always seek the advice of your physician or other qualified health provider regarding medical conditions. REFERENCES: https://www.researchgate.net/publication/236279897_Use_of_dinitrophenol_in_obesity_and_related_conditions_Final_report https://www.researchgate.net/publication/5833165_Use_of_Dinitrophenol_in_Nutritional_Disorders_A_Critical_Survey_of_Clinical_Results https://www.researchgate.net/publication/7087648_Relationship_between_blood_cholesterol_and_increased_metabolism_from_dinitrophenol_and_thyroid https://www.researchgate.net/publication/285049903_Febrile_respiratory_and_some_other_actions_of_dinitrophenol https://www.researchgate.net/publication/236310875_Actions_and_uses_of_dinitrophenol_Promising_metabolic_applications https://www.coursehero.com/file/p5qclku/Biological-Study-of-Dinitro-Drugs-in-Humans-By-Dr-Jacques-Bell-Bell-Jacques/ https://www.researchgate.net/publication/285033172_Dinitrophenol_in_the_treatment_of_obesity https://www.researchgate.net/publication/236287135_Metabolic_actions_of_dinitrophenol_with_the_use_of_balanced_and_unbalanced_diets https://www.researchgate.net/publication/236323763_CLINICAL_CIRCULATORY_EFFECTS_OF_DINITROPHENOL https://medcraveonline.com/PPIJ/PPIJ-04-00096 https://www.drugbank.ca/drugs/DB04528 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2444737/ https://patents.google.com/patent/US4673691A/en https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1315023/ https://www.ncbi.nlm.nih.gov/pubmed/11871126 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1187562/ https://www.ncbi.nlm.nih.gov/pubmed/16238490 https://www.ncbi.nlm.nih.gov/pubmed/14885489 https://www.ncbi.nlm.nih.gov/pubmed/21177364 https://www.ncbi.nlm.nih.gov/pubmed/2450196 https://www.ncbi.nlm.nih.gov/pubmed/18461559
Wow this is the 300th episode of BFR and I wanted to make it special! So, we're talking about the little known potential health benefits of the popular mitochondrial uncoupler, 2,4 Dinitrophenol AKA DNP! Before anyone turns their nose up at hearing this, LISTEN TO THE EPISODE AND READ THE RESEARCH YOURSELF! I'm not inventing anything new or ground breaking here, these are literally facts and some very interesting facts at that! So enjoy the 300th episode of Beast Fitness Radio and here's to the next 300! REFERENCES https://www.researchgate.net/publication/236279897_Use_of_dinitrophenol_in_obesity_and_related_conditions_Final_report https://www.researchgate.net/publication/5833165_Use_of_Dinitrophenol_in_Nutritional_Disorders_A_Critical_Survey_of_Clinical_Results https://www.researchgate.net/publication/7087648_Relationship_between_blood_cholesterol_and_increased_metabolism_from_dinitrophenol_and_thyroid https://www.researchgate.net/publication/285049903_Febrile_respiratory_and_some_other_actions_of_dinitrophenol https://www.researchgate.net/publication/236310875_Actions_and_uses_of_dinitrophenol_Promising_metabolic_applications https://www.coursehero.com/file/p5qclku/Biological-Study-of-Dinitro-Drugs-in-Humans-By-Dr-Jacques-Bell-Bell-Jacques/ https://www.researchgate.net/publication/285033172_Dinitrophenol_in_the_treatment_of_obesity https://www.researchgate.net/publication/236287135_Metabolic_actions_of_dinitrophenol_with_the_use_of_balanced_and_unbalanced_diets https://www.researchgate.net/publication/236323763_CLINICAL_CIRCULATORY_EFFECTS_OF_DINITROPHENOL https://medcraveonline.com/PPIJ/PPIJ-04-00096 https://www.drugbank.ca/drugs/DB04528 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2444737/ https://patents.google.com/patent/US4673691A/en https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1315023/ https://www.ncbi.nlm.nih.gov/pubmed/11871126 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1187562/ https://www.ncbi.nlm.nih.gov/pubmed/16238490 https://www.ncbi.nlm.nih.gov/pubmed/14885489 https://www.ncbi.nlm.nih.gov/pubmed/21177364 https://www.ncbi.nlm.nih.gov/pubmed/2450196 https://www.ncbi.nlm.nih.gov/pubmed/18461559 •••SUPPORT OUR SPONSORS••• (COACHING) Alex - www.theprepcoach.com (FREE OPEN FORUM w/ EXCLUSIVE VIDEOS) http://www.theprepcoachforum.com (SUPPLEMENTS) www.projectad.me___use discount code “BFR25” to save off your order! (RESEARCH CHEMS) www.maresearchchems.net___use discount code “alex15” to save off your order! (SPECIALTY SUPPS) www.masupps.com___use discount code “alex20” to save off your order! (BULK SUPPLEMENTS) www.truenutrition.com___use discount code “AXK5” to save off your order! •••FIND THE EPISODES••• ITUNES:https://itunes.apple.com/us/podcast/beastfitness-radios-podcast/id1065532968 LIBSYN:http://beastfitnessradio.libsyn.com VIMEO: www.vimeo.com/theprepcoach •••PREP COACH APPAREL••• https://teespring.com/stores/the-prep-coach-apparel
Episode 296 is an introduction episode to the "Fat Burner" Family Tree concept which is harder to make than you'd think as EVERY pathway has so many interactions with the others it makes it somewhat difficult to split them into separate "families." So with that being said this is simply the 1st part of the Fat Burner Family Tree as I finalize the rest of this project! REFERENCES https://www.researchgate.net/publication/236279897_Use_of_dinitrophenol_in_obesity_and_related_conditions_Final_report https://www.researchgate.net/publication/5833165_Use_of_Dinitrophenol_in_Nutritional_Disorders_A_Critical_Survey_of_Clinical_Results https://www.researchgate.net/publication/7087648_Relationship_between_blood_cholesterol_and_increased_metabolism_from_dinitrophenol_and_thyroid https://www.researchgate.net/publication/285049903_Febrile_respiratory_and_some_other_actions_of_dinitrophenol https://www.researchgate.net/publication/236310875_Actions_and_uses_of_dinitrophenol_Promising_metabolic_applications https://www.coursehero.com/file/p5qclku/Biological-Study-of-Dinitro-Drugs-in-Humans-By-Dr-Jacques-Bell-Bell-Jacques/ https://www.researchgate.net/publication/285033172_Dinitrophenol_in_the_treatment_of_obesity https://www.researchgate.net/publication/236287135_Metabolic_actions_of_dinitrophenol_with_the_use_of_balanced_and_unbalanced_diets https://www.researchgate.net/publication/236323763_CLINICAL_CIRCULATORY_EFFECTS_OF_DINITROPHENOL https://medcraveonline.com/PPIJ/PPIJ-04-00096 https://www.drugbank.ca/drugs/DB04528 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2444737/ https://patents.google.com/patent/US4673691A/en https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1315023/ https://www.ncbi.nlm.nih.gov/pubmed/11871126 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1187562/ https://www.ncbi.nlm.nih.gov/pubmed/16238490 https://www.ncbi.nlm.nih.gov/pubmed/14885489 https://www.ncbi.nlm.nih.gov/pubmed/21177364 https://www.ncbi.nlm.nih.gov/pubmed/2450196 https://www.ncbi.nlm.nih.gov/pubmed/18461559 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085709/ https://www.ncbi.nlm.nih.gov/pubmed/29320480 https://www.ncbi.nlm.nih.gov/pubmed/25943561 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5614479/ https://clinicaltrials.gov/ct2/show/NCT00158899 https://www.ncbi.nlm.nih.gov/pubmed/11103222 https://www.ncbi.nlm.nih.gov/pubmed/8201901 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3649093/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC155439/ https://www.ncbi.nlm.nih.gov/pubmed/16840650 https://www.ncbi.nlm.nih.gov/pubmed/10209080 https://www.ncbi.nlm.nih.gov/pubmed/2000046 https://www.ncbi.nlm.nih.gov/pubmed/1949202 https://www.ncbi.nlm.nih.gov/pubmed/1345887 https://www.ncbi.nlm.nih.gov/pubmed/16603237 https://www.ncbi.nlm.nih.gov/pubmed/17068216 https://www.ncbi.nlm.nih.gov/pubmed/22820505 https://www.ncbi.nlm.nih.gov/pubmed/8388847 https://www.ncbi.nlm.nih.gov/pubmed/9464899 https://www.ncbi.nlm.nih.gov/pubmed/10499369 https://www.ncbi.nlm.nih.gov/pubmed/3830935 https://adc.bmj.com/content/archdischild/87/4/323.full.pdf https://www.ncbi.nlm.nih.gov/pubmed/9827665 https://www.ncbi.nlm.nih.gov/pubmed/6408016 https://www.ncbi.nlm.nih.gov/pubmed/14557420 https://www.ncbi.nlm.nih.gov/pubmed/14557419 https://www.ncbi.nlm.nih.gov/pubmed/17560731 https://www.ncbi.nlm.nih.gov/pubmed/21710402 https://www.ncbi.nlm.nih.gov/pubmed/1777550 https://www.ncbi.nlm.nih.gov/pubmed/6145164 (https://www.ncbi.nlm.nih.gov/pubmed/21319959) (https://www.ncbi.nlm.nih.gov/pubmed/12530470) (https://www.ncbi.nlm.nih.gov/pubmed/22922125)(https://www.ncbi.nlm.nih.gov/pubmed/17095930) (https://www.ncbi.nlm.nih.gov/pubmed/14965188) (https://www.ncbi.nlm.nih.gov/pubmed/11997383) (https://www.ncbi.nlm.nih.gov/pubmed/15058305) (https://www.ncbi.nlm.nih.gov/pubmed/17264220) (https://www.ncbi.nlm.nih.gov/pubmed/19059538) (https://www.ncbi.nlm.nih.gov/pubmed/22027215) (https://www.ncbi.nlm.nih.gov/pubmed/17202835) (https://www.ncbi.nlm.nih.gov/pubmed/23118793)(https://www.ncbi.nlm.nih.gov/pubmed/23808999)(https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2410097/) (https://www.ncbi.nlm.nih.gov/pubmed/23683609)(https://www.ncbi.nlm.nih.gov/pubmed/20022616)(https://www.ncbi.nlm.nih.gov/pubmed/16873787)(https://www.ncbi.nlm.nih.gov/pubmed/12550067)(https://www.ncbi.nlm.nih.gov/pubmed/17303791)(https://www.ncbi.nlm.nih.gov/pubmed/10448525)https://www.ncbi.nlm.nih.gov/pubmed/3275760)(https://www.ncbi.nlm.nih.gov/pubmed/9160809)(https://www.ncbi.nlm.nih.gov/pubmed/9056266)(https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/104057/citedby/?tool=pubmed)(https://www.ncbi.nlm.nih.gov/pubmed/9096856)(https://www.ncbi.nlm.nih.gov/pubmed/22172158)(https://www.ncbi.nlm.nih.gov/pubmed/6772742)(https://www.ncbi.nlm.nih.gov/pubmed/13479136)(https://www.ncbi.nlm.nih.gov/pubmed/11508317)(https://www.ncbi.nlm.nih.gov/pubmed/20372701)(https://www.ncbi.nlm.nih.gov/pubmed/9109644)(https://www.ncbi.nlm.nih.gov/pubmed/8387037) (https://www.ncbi.nlm.nih.gov/pubmed/22423897)(https://www.ncbi.nlm.nih.gov/pubmed/10812920)(https://www.ncbi.nlm.nih.gov/pubmed/21462332)(https://www.ncbi.nlm.nih.gov/pubmed/21711570)(https://www.ncbi.nlm.nih.gov/pubmed/21538147) (https://www.ncbi.nlm.nih.gov/pubmed/9762007)(https://www.ncbi.nlm.nih.gov/pubmed/19930003)(https://www.ncbi.nlm.nih.gov/pubmed/14633804)(https://www.ncbi.nlm.nih.gov/pubmed/16634838)(https://www.ncbi.nlm.nih.gov/pubmed/20924865)(https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3767714/)(https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5067830/) •••SUPPORT OUR SPONSORS••• (COACHING) Alex - www.theprepcoach.com (FREE OPEN FORUM w/ EXCLUSIVE VIDEOS) http://www.theprepcoachforum.com (SUPPLEMENTS) www.projectad.me___use discount code “BFR25” to save off your order! 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Episode 238 is a follow up to my previous podcast where I talked about the original clinical trials on DNP and broke down what REALLY happens internally on this drug. Now, I wanted to present the compilation of bloodwork that I've received over the years from clients and non-clients who have utilized DNP in the trenches to show you what potential markers may or may not go out of range if you chose to utilize this compound. As always this is purely the knowledge for you to make your own informed decision. Be an adult, do the research, and decide for yourself. Do not simply listen to the never-ending stories from people about how bad DNP is yet they push diuretics and trenbolone through the roof. REFERENCES https://www.researchgate.net/publication/236279897_Use_of_dinitrophenol_in_obesity_and_related_conditions_Final_report https://www.researchgate.net/publication/5833165_Use_of_Dinitrophenol_in_Nutritional_Disorders_A_Critical_Survey_of_Clinical_Results https://www.researchgate.net/publication/7087648_Relationship_between_blood_cholesterol_and_increased_metabolism_from_dinitrophenol_and_thyroid https://www.researchgate.net/publication/285049903_Febrile_respiratory_and_some_other_actions_of_dinitrophenol https://www.researchgate.net/publication/236310875_Actions_and_uses_of_dinitrophenol_Promising_metabolic_applications https://www.coursehero.com/file/p5qclku/Biological-Study-of-Dinitro-Drugs-in-Humans-By-Dr-Jacques-Bell-Bell-Jacques/ https://www.researchgate.net/publication/285033172_Dinitrophenol_in_the_treatment_of_obesity https://www.researchgate.net/publication/236287135_Metabolic_actions_of_dinitrophenol_with_the_use_of_balanced_and_unbalanced_diets https://www.researchgate.net/publication/236323763_CLINICAL_CIRCULATORY_EFFECTS_OF_DINITROPHENOL https://medcraveonline.com/PPIJ/PPIJ-04-00096 https://www.drugbank.ca/drugs/DB04528 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2444737/ https://patents.google.com/patent/US4673691A/en https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1315023/ https://www.ncbi.nlm.nih.gov/pubmed/11871126 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1187562/ https://www.ncbi.nlm.nih.gov/pubmed/16238490 https://www.ncbi.nlm.nih.gov/pubmed/14885489 https://www.ncbi.nlm.nih.gov/pubmed/21177364 https://www.ncbi.nlm.nih.gov/pubmed/2450196 https://www.ncbi.nlm.nih.gov/pubmed/18461559 •••SUPPORT OUR SPONSOR••• (COACHING) Alex - www.theprepcoach.com (FREE OPEN FORUM w/ EXCLUSIVE VIDEOS) http://www.theprepcoachforum.com (SUPPLEMENTS) www.projectad.me___use discount code “BFR25” to save off your order! (HPLC TESTED PEPTIDES) www.maresearchchems.com___use discount code “alex15” to save off your order! (SPECIALITY SUPPLEMENTS) www.masupps.com___use discount code “alex20” to save off your order! (INJECTABLE L-CARNITINE) www.synthetek.com___use discount code “alexkikel” to save off your order! (BULK SUPPLEMENTS) www.truenutrition.com___use discount code “AXK5” to save off your order! •••FIND THE EPISODES••• ITUNES:https://itunes.apple.com/us/podcast/beastfitness-radios-podcast/id1065532968 LIBSYN:http://beastfitnessradio.libsyn.com VIMEO: www.vimeo.com/theprepcoach YOUTUBE: https://www.youtube.com/c/ThePrepCoach •••PREP COACH APPAREL••• https://teespring.com/stores/the-prep-coach-apparel
Dr. Jack West reviews the preliminary clinical results on the IMpower150 trial that tested the value of adding the immune checkpoint inhibitor atezolizumab to carbo/paclitaxel/bevacizumab in patients with chemo-naïve advanced non-squamous NSCLC.
Doblin on Peyote: Legality, Safety & Clinical Results by Dr. Richard L. Miller
Doblin on LSD: Addiction, Clinical Results & Spirituality by Dr. Richard L. Miller
Doblin on Peyote: Legality, Safety & Clinical Results by Dr. Richard L. Miller
Whitaker on SSRIs: History & Clinical Results by Dr. Richard L. Miller
Whitaker on SSRIs: Clinical Results & Long-Term Depression by Dr. Richard L. Miller
Whitaker on SSRIs: Clinical Results, Depression & Exercise by Dr. Richard L. Miller
Whitaker on SSRIs: Clinical Results, Safety & Depression by Dr. Richard L. Miller
Doblin on MDMA: Safety, Clinical Results & User Experience by Dr. Richard L. Miller
Doblin on Ibogaine: User Experience, Addiction, Clinical Results & Safety by Dr. Richard L. Miller
Doblin on MDMA: Clinical Results & Risks by Dr. Richard L. Miller
Grob on MDMA: Clinical Results & Safety by Dr. Richard L. Miller
Mithoefer on MDMA: Clinical Results by Dr. Richard L. Miller
McKenna on Ayahuasca: Overview, Clinical Results & Addiction by Dr. Richard L. Miller
Grob on Ayahuasca: Clinical Results by Dr. Richard L. Miller
Grob on Ayahuasca: Clinical Results & Addiction by Dr. Richard L. Miller
Grob on Psilocybin: Clinical Results & Anxiety by Dr. Richard L. Miller
Grob on Psilocybin: Clinical Results by Dr. Richard L. Miller
XDx employee Tod Klingler discusses the development of molecular diagnostics and how the recent advances in technology have affected the field of medicine. (February 10, 2009)
This podcast covers the JBJS issue for November 2009. Featured are articles covering Predisposing Factors for Recurrent Shoulder Dislocation After Arthroscopic Treatment; Comparison of the Clinical Results of Three Posterior Cruciate Ligament Reconstruction Techniques; Bilateral Low-Energy Simultaneous or Sequential Femoral Fractures in Patients on Long-Term Alendronate Therapy; recorded commentary by Dr. Lane; Thromboprophylaxis in Patients with Acute Spinal Injuries: An Evidence-Based Analysis; Extracorporeal Shock-Wave Therapy Compared with Surgery for Hypertrophic Long-Bone Nonunions.
This podcast covers the JBJS issue for November 2009. Featured are articles covering Predisposing Factors for Recurrent Shoulder Dislocation After Arthroscopic Treatment; Comparison of the Clinical Results of Three Posterior Cruciate Ligament Reconstruction Techniques; Bilateral Low-Energy Simultaneous or Sequential Femoral Fractures in Patients on Long-Term Alendronate Therapy; recorded commentary by Dr. Lane; Thromboprophylaxis in Patients with Acute Spinal Injuries: An Evidence-Based Analysis; Extracorporeal Shock-Wave Therapy Compared with Surgery for Hypertrophic Long-Bone Nonunions.