Podcasts about febrile

Increased body temperature due to an inflammatory response

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Best podcasts about febrile

Latest podcast episodes about febrile

Blood Cancer Talks
Episode 72. frontMIND Trial in DLBCL with Dr. Charles Herbaux

Blood Cancer Talks

Play Episode Listen Later Jun 21, 2026 41:02


Episode OverviewFor the second time in two decades, a phase 3 trial has shown a statistically significant improvement over R-CHOP in newly diagnosed diffuse large B-cell lymphoma (DLBCL). In this episode, Eddie, Raj, and Ashwin sit down with Professor Charles Herbaux to unpack the data, debate the clinical implications, and ask the question that's on every hematologist's mind: is this enough to change practice?Background: Setting the Stage for TafasitamabBefore diving into frontMIND, the episode provides context on tafasitamab, a CD19-targeting monoclonal antibodyL-MIND (Phase 2 — relapsed/refractory DLBCL):81 patients with R/R DLBCLORR 58%, complete response rate 41%Established activity of tafasitamab + lenalidomide in the relapsed settinghttps://pubmed.ncbi.nlm.nih.gov/32511983/First-MIND (Phase 1b — frontline DLBCL, IPI 2–5):66 patients randomized: tafa-R-CHOP (n=33) vs. tafa-len-R-CHOP (n=33)ORR: 75.8% vs. 81.8%, respectivelySerious treatment-emergent adverse events: 42.4% vs. 51.5%Provided the signal (and the safety caution) to move to phase 3https://pubmed.ncbi.nlm.nih.gov/37369099/The frontMIND TrialDesign: Phase 3, double-blind, placebo-controlled randomized trialIntervention: R-CHOP + tafasitamab (12 mg/kg IV days 1, 8, 15 per cycle) + lenalidomide (25 mg/day, days 1–10 per cycle)Control: R-CHOP + placebosGCSF mandatory (given double-blind design); VTE prophylaxis (heparin or aspirin) mandatory given lenalidomideEnrollment: May 2021 – March 2023; 899 patients randomizedPrimary endpoint: Investigator-assessed progression-free survival (PFS)Patient Population:Age 18–80; DLBCL or high-grade B-cell lymphoma, IPI 3–5Median age: 65 years96% advanced stage; 54% bulky disease; 31% ECOG PS 2; 82% elevated LDH55% IPI 3 / aaIPI 2; 43% IPI 4–5 / aaIPI 38% double/triple hit — a high-risk subgroup included despite R-CHOP being the controlBroad histologic inclusion: transformed lymphoma, grade 3B FL, T-cell/histiocyte-rich LBCL, EBV+ DLBCL, ALK+ LBCL, HHV8+ DLBCL Note: On retrospective central review, ~7% of patients had a different histology (roughly half had FL grade 1–3A), underscoring the diagnostic challenges in DLBCL~40% received pre-phase steroids; 8% rituximab; 4% vincristine prior to cycle 1Key Efficacy Results(Primary analysis at median follow-up 35.2 months) | Endpoint | Tafa-Len-R-CHOP | R-CHOP | HR / p-value | 2-year PFS | 71.1% | 62.9% | HR 0.75, p=0.0194 | 3-year PFS | 67.3% | 60.7% | ~6.6% absolute difference | Overall Survival | — | — | HR 0.85, p=0.27 (immature)Points of Discussion:Absolute PFS benefit at 2 years: ~8.2%; at 3 years: ~6.6% — a modest but statistically significant improvementOS curves cross early, then separate slightly from ~18 months; data remain immatureEarly censoring observed: ~17% (intervention) and ~14% (control) censored by 9 months — raises questions about off-protocol therapySubgroup consistency: PFS benefit appeared consistent across prespecified subgroups; specific subgroups discussed in the episodeSafety Adverse Event | Tafa-Len-R-CHOP | R-CHOP | Fatal treatment-emergent AEs | 6% (26 pts) | 4% (17 pts) | Diarrhea (any grade) | 25% | 17% | Febrile neutropenia | 17% (incl. 1 death) | 13% | Grade ≥3 anemia | 24% | 17% | Grade ≥3 thrombocytopenia | 27% | 14%The addition of tafasitamab and lenalidomide to R-CHOP adds meaningful hematologic toxicity, particularly thrombocytopenia and anemia, as well as diarrhea and febrile neutropenia.Key Discussion Points from the EpisodeDid the early-phase L-MIND and First-MIND data justify bringing tafasitamab into the front-line setting, and was tafa-len-R-CHOP the right intervention arm to take forward?Is R-CHOP the appropriate control for a patient population that includes 8% double/triple hit lymphoma?What are the implications of using investigator-assessed PFS as the primary endpoint — and how critical is effective blinding to the integrity of that endpoint?How do we interpret the early OS curve crossing and currently non-significant OS benefit?Is the ~8% absolute PFS improvement at 2 years clinically meaningful enough to change practice — particularly given the added toxicity?How should we think about patient selection: who would you prioritize for tafa-len-R-CHOP over standard R-CHOP in clinical practice?What does frontMIND mean for the DLBCL treatment landscape alongside polatuzumab-R-CHP (POLARIX)?Resources & Further ReadingfrontMIND trial: Lenz et al. Lancet. https://pubmed.ncbi.nlm.nih.gov/42217458/POLARIX: Tilly H, et al. NEJM 2022About BloodCancerTalksBloodCancerTalks is a medical education podcast hosted by Raj, Ashwin, and Eddie, dedicated to the latest advances in hematologic malignancies. New episodes available wherever you listen to podcasts.Follow us on X/Twitter for episode updates and hematology/oncology content. 

EMplify by EB Medicine
Febrile Travelers

EMplify by EB Medicine

Play Episode Listen Later May 27, 2026 23:03


In this episode, Sam Ashoo, MD and Dr. T.R. Eckler, MD discuss the May 2026 Emergency Medicine Practice article, Emergency Department Evaluation and Management of Serious and High-Risk Infections in the Febrile Returning Traveler.0:16 — Podcast Introduction1:08 — Episode Introduction7:30 — Malaria13:55 — Dengue17:33 — Enteric Fever (Typhoid/Paratyphoid)20:53 — Leptospirosis22:43 — Clinical Presentations26:33 — Diagnostic Testing33:17 — Treatment38:59 — Special Populations & Risk Pitfalls43:05 — Closing Pearls & OutroSubscribers, take the CME test here. Emergency Medicine Residents, get your free subscription by writing resident@ebmedicine.net

The Plant Path
5 Top Herbs for Treating Fever (A Vitalist Guide)

The Plant Path

Play Episode Listen Later May 20, 2026 44:15


 Let's be honest, fevers suck, and they make you feel miserable. But should we make the fever go away so we can feel better? Actually, no, that would be a mistake. Fever is an intelligent response of the body that should be supported rather than suppressed. It plays a very important role in healing the body, and this has shaped the perspectives and practices of traditional herbalists since humans first began using plants as medicine.    In this post, we'll discuss the purpose of fevers, how to treat them, and I'll delve into my top five diaphoretic herbs for supporting the body through the febrile response.   Option 2 for intro -  Febrile illnesses can be intense, prolonged, and very taxing, but from a clinical herbalism perspective, fever is not something to fear or to suppress. This article explores how to work with the intelligence of fever using traditional diaphoretic strategies to support resolution, rather than suppression.   Here's what you'll learn: Why fever is a vital, intelligent healing response and usually shouldn't be suppressed  The core principle of treating febrile conditions regardless of pathogen (virus, bacteria, etc.) The difference between stimulant and relaxant diaphoretics, and when to use each type How diaphoretics support the body by driving heat outward and relieving surface tension Why hot water and tea preparation enhance the effectiveness of diaphoretic herbs How to match herbs to the stage and presentation of the fever  A clinical breakdown of five key febrile remedies: Elderflower, Lemon Balm, Yarrow, Black Cohosh, and Boneset, and how and when to use each herb with preparation information Why the term "antiviral" is often misleading, and how to think more precisely about herbal actions How to formulate teas for palatability, strength, and compliance The role of fasting during fever and restoring digestion afterward Additional herbal allies from the kitchen and clinic for febrile support Other supportive therapies for fever A step-by-step therapeutic regimen for fever support and recovery Why suppressing a fever can prolong illness, and how proper herbal treatment can shorten its duration ———————————— CONNECT WITH SAJAH AND WHITNEY ———————————— To get free in depth mini-courses and videos, visit our blog at:  http://www.evolutionaryherbalism.com   Get daily inspiration and plant wisdom on our Facebook and Instagram channels: http://www.facebook.com/EvolutionaryHerbalism https://www.instagram.com/evolutionary_herbalism/   Be sure to subscribe to our YouTube Channel: https://www.youtube.com/channel/UCyP63opAmcpIAQg1M9ShNSQ   Get a free 5-week course when you buy a copy of the book, Evolutionary Herbalism: https://www.evolutionaryherbalism.com/evolutionary-herbalism-book/   Shop our herbal products:  https://naturasophiaspagyrics.com/   ———————————— ABOUT THE PLANT PATH ———————————— The Plant Path is a window into the world of herbal medicine. With perspectives gleaned from traditional Western herbalism, Ayurveda, Chinese Medicine, Alchemy, Medical Astrology, and traditional cultures from around the world, The Plant Path provides unique insights, skills and strategies for the practice of true holistic herbalism. From clinical to spiritual perspectives, we don't just focus on what herbs are "good for," but rather who they are as intelligent beings, and how we can work with them to heal us physically and consciously evolve.   ———————————— ABOUT SAJAH ———————————— Sajah Popham is the author of Evolutionary Herbalism and the founder of the School of Evolutionary Herbalism, where he trains herbalists in a holistic system of plant medicine that encompasses clinical Western herbalism, medical astrology, Ayurveda, and spagyric alchemy. His mission is to develop a comprehensive approach that balances the science and spirituality of plant medicine, focusing on using plants to heal and rejuvenate the body, clarify the mind, open the heart, and support the development of the soul. This is only achieved through understanding and working with the chemical, energetic, and spiritual properties of the plants. His teachings embody a heartfelt respect, honor and reverence for the vast intelligence of plants in a way that empowers us to look deeper into the nature of our medicines and ourselves. He lives on a homestead in the foothills of Mt. Baker Washington with his wife Whitney where he teaches, consults clients, and prepares spagyric herbal medicines.    ———————————— WANT TO FEATURE US ON YOUR PODCAST? ———————————— If you'd like to interview Sajah or Whitney to be on your podcast, click here to fill out an interview request form.

In conversation with...
Ulrikka Nygaard and Nadja Vissing on antibiotic treatment in children with high-risk febrile neutropenia

In conversation with...

Play Episode Listen Later May 11, 2026 23:13 Transcription Available


This episode considers how antibiotic use can be safely reduced in children in high-risk scenarios or with severe infections. To discuss this we are joined by Dr Nadja Vissing and Dr Ulrikka Nygaard, paediatric infectious disease specialists from Copenhagen University Hospital, who led a randomized controlled trial in Denmark evaluating the early discontinuation of empirical antibiotics versus extended treatment in children with cancer and high-risk febrile neutropenia. We hear about the importance of this trial for children with cancer and their families as well as for broader antimicrobial stewardship. We discuss other recent RCTs that are informing safely reducing antibiotic exposure in children with urinary tract infections, uncomplicated bone and joint infections and probable early onset neonatal sepsis. Nadja and Ulrikka share with listeners their take home messages related to antibiotic decision-making from these trials along with words of wisdom and motivation for other paediatric clinical trialists. Click here to read the full article: https://www.thelancet.com/journals/lanchi/article/PIIS2352-4642(26)00039-8/fulltext

PediaCast CME
Febrile Neonates: Can We Safely Skip the Lumbar Puncture? - PediaCast CME 121

PediaCast CME

Play Episode Listen Later May 5, 2026 56:38


Dr Brett Burstein and Dr Nathan Kuppermann visit the studio as we consider febrile neonates ≤28 days of age. Can we skip the lumbar puncture in low-risk babies? What constitutes low risk? And how can we employ shared decision-making with parents of these infants? Tune in for this important conversation!

ACEP Critical Decisions in Emergency Medicine
March 2026: Pneumothorax Management and Pediatric Febrile Rashes

ACEP Critical Decisions in Emergency Medicine

Play Episode Listen Later Apr 14, 2026 30:32


In the March 2026 episode of Critical Decisions in Emergency Medicine, Drs. Danya Khoujah and Wendy Chang discuss pneumothorax management and pediatric febrile rashes. As always, you'll also hear about the hot topics covered in the regular features, including recurrent syncope in a patient with gastroenteritis in The Critical ECG, a case of pulmonary embolism in Clinical Pediatrics, sternoclavicular joint septic arthritis in Critical Cases in Orthopedics and Trauma, ultrasound-guided subacromial injection in The Critical Procedure, peripheral vasopressor use for early sepsis-induced hypotension in The Literature Review, a patient with a sore throat in The Critical Image, flucytosine in The Drug Box, and nickel carbonyl toxicity in The Tox Box.

Healthy Children
The Latest on Childhood Vaccines: Measles, Febrile Seizures and Newborn Shots – Ep. 76

Healthy Children

Play Episode Listen Later Mar 26, 2026 12:29


Dr. Ari Brown joins guest host Dr. Jennifer Shu to talk about childhood vaccines. They share the latest update about the measles outbreaks in the U.S. and what they mean for the disease's elimination status. They also delve into shifting federal recommendations, the facts around febrile seizures and why the vitamin K shot remains essential for newborns. For resources go to healthychildren.org/podcast.

shots newborn measles seizures febrile childhood vaccines ari brown jennifer shu
Kids Healthcast
Episode 177: Screen time, helping children cope with doctor visits and febrile seizures

Kids Healthcast

Play Episode Listen Later Mar 7, 2026 19:22


Join Drs. Manson, Atieno and Anstine as they talk about screen time, helping your child cope with pediatrician visits and febrile seizures, along with some fun trivia and a parenting tip for the month! Topics and timestamps: Screen time: 1:45 Helping children cope with pediatrician visits: 3:31 Parenting tip: 8:18 Febrile seizures: 11:21 Trivia: 16:52 Conclusion: 18:17

REBEL Cast
REBEL Core Cast 150.0: Emergency Medicine Consults: How to Call a Consult + Handle Pushback (With Scripts)

REBEL Cast

Play Episode Listen Later Feb 12, 2026


🧭 REBEL Rundown 📌 Key Points The 4 Steps of an ED Consult:👋 Introduce yourself and your role🎯 Lead with the outcome (the ask)🧾 Give a focused case summary (why it’s theirs + what you’ve done)🔁 Close the loop (timeline, next steps, contingencies) Click here for Direct Download of the Podcast. 📝 Introduction Today we’re tackling one of the most important (and most under-taught) skills in emergency medicine: how to call a consult in the ED and what to do when a consultant pushes back.To call a consult in the ED, start with a brief introduction, lead with the outcome you need (“the ask”), give a focused decision-relevant summary, and close the loop with timeline and next steps. If the consultant resists, clarify the “why,” restate the ask, offer alternatives, and escalate when patient safety or disposition is at risk.After two decades in emergency medicine and countless consult calls, here’s a simple framework—plus copy/paste scripts—to make your consults faster, clearer, and easier to say “yes” to. 🤔 Why Consult Skills Matter in Emergency Medicine Consults aren’t a formality—they’re a patient-care intervention. Strong consult communication:Reduces delays in time-sensitive careImproves ED throughput and dispositionDecreases conflict and miscommunicationClarifies ownership and next stepsProtects the patient (and the team) when plans are unclear 🪜 The 4-Step ED Consult Framework (Introduction → Ask → Summary → Close the Loop) Most consult friction comes from one of two problems: unclear expectations or excessive noise. This four-step structure solves both.1) Introduce yourself and your roleA simple intro sets a professional tone and removes ambiguity.Script: “Hey, this is Swami, one of the ED attendings. I’m calling for an ortho consult.” 2) Lead with the outcome (the ask)Don’t bury the lede. The consultant wants to know what you need—immediately.Script: “I’m calling about a patient with a suspected septic knee. I need you to evaluate for operative management.” 3) Give a focused, decision-relevant summaryYour summary should answer:Why this is your service’s problemWhat’s already been doneWhat I’m worried about / what decision is needed nowScript: “43-year-old man with no major PMH, 3 days of knee pain and swelling. XR negative. Febrile. Aspiration yielded purulent fluid—cultures sent. We started antibiotics after the tap. He’s hemodynamically stable.” High-yield pearl: Add quick “stability anchors” when relevant:“Airway stable, pain controlled.”“Neurovascularly intact.”“No signs of compartment syndrome.”“No hypotension or escalating oxygen requirement.” 4) Close the loop (timeline + next steps)This prevents the consult from floating in limbo and protects patient flow.Script: “When do you expect to see the patient, and do you want anything done before you arrive—NPO, repeat labs, additional imaging?” 📝 ED Consult Script General ED Consult Script “Hi, this is Dr. ___ in the ED. I’m calling for a ___ consult. The reason is ___. Briefly: ___ year-old with ___. We’ve done ___ and started ___. I’m concerned about ___. Can you see them today, and what’s your preferred next step?” Septic joint / Ortho Example “Hi, this is Swami in the ED. I need an ortho consult for suspected septic arthritis. 43-year-old with 3 days of atraumatic knee swelling and fever. XR negative. Tap produced purulent fluid—cultures sent. Antibiotics started after aspiration. Can you evaluate for operative management, and when can you see the patient?” Neurology example (time-sensitive) “Hi, this is Dr. ___ in the ED. I need neurology for suspected acute stroke. Last known well ___. NIHSS ___. CT/CTA completed (or pending). I’m calling to discuss candidacy for thrombolysis/thrombectomy and next steps. When can you evaluate and what additional workup do you want now?” ⛓️‍💥 Common ED Consult Mistakes (and Fixes) Mistake: Long story before the askFix: Lead with the outcome in the first sentenceMistake: Unfiltered data dumpFix: Provide only decision-relevant detailsMistake: No timelineFix: Ask explicitly when they’ll see the patient and what they need firstMistake: Implicit “ownership”Fix: Clarify who is admitting, who is following, and what happens if the patient worsens ✋ What to Do When a Consultant Pushes Back Even a perfect consult can meet resistance. Your job is to stay calm, keep it professional, and protect the patient.1) Ask “why?”Don’t argue first—diagnose the refusal.Script: “Help me understand your concern about seeing this patient.” Many refusals are based on misunderstanding: wrong service, missing key detail, or incorrect assumption about stability.2) Restate the consult in one sentence, then offer optionsIf the conversation starts spiraling, reset it.Script: “To be clear, I’m concerned this is septic arthritis and needs ortho evaluation. If you don’t feel you’re the right service, who should be—rheum, medicine, or another surgical team?” This keeps you collaborative while preventing dead ends.3) Humanize the decision (use sparingly)This is a “high-voltage” tool. Use it when stakes are high and you’ve already clarified the medical facts.Script: “I’m worried we’re missing something time-sensitive. If this were your family member, what would you want us to do next?” Use it to re-anchor to patient risk—not as a guilt tactic. ⚡️When and How to Escalate a Consult Escalation isn’t personal—it’s a safety mechanism when there’s an impasse that threatens timely care.When to escalateTime-sensitive condition is delayed (e.g., septic joint, cord compression, testicular torsion, GI bleed with instability)No clear disposition plan despite reasonable ED evaluationConsultant refusal blocks needed specialty decision-makingPatient safety or deterioration risk is increasing in the ED How to escalate (lowest to highest intensity)Ask for the consultant’s attending (if speaking to a resident)Call the on-call attending directlyInvolve ED leadership/medical directorEscalate to service chief/department chair (rare, but real)Hospital supervisor/admin escalation for immediate operational impasseScript: “We’re at an impasse and the patient needs a decision. I’m escalating to clarify ownership and ensure timely care.” ️ Documentation Tips for Consult Refusals Documentation should be factual and patient-centered, not punitive.Include:Your clinical concern and why the consult is neededWho you spoke with (name/role)Their stated reason for refusal or delayAlternatives discussedEscalation steps taken and final plan 👉 FAQ: Emergency Medicine Consults What is the best way to call a consult in the ED?Introduce yourself, lead with the specific ask, summarize only decision-relevant details, and close the loop with a clear plan and timeline.What should I say when a consultant refuses to see a patient?Ask why, clarify misunderstandings, restate your concern and the ask, and request an alternative plan or appropriate service.When should I escalate a consult?Escalate when an impasse delays time-sensitive care, threatens patient safety, or prevents appropriate disposition.How do I document a refused consult?Document the clinical concern, who you spoke with, their stated reason, alternatives discussed, and escalation steps taken. 🏁 Conclusion Mastering emergency medicine consults makes you faster, safer, and easier to work with. The goal isn’t to “win” a consult call—it’s to get the patient the right care, with clear ownership and a shared plan. Post Peer Reviewed By: Marco Propersi, DO (Twitter/X: @Marco_propersi), and Mark Ramzy, DO (X: @MRamzyDO) 👤 Associate Editor Anand Swaminathan MD, MPH All Things REBEL EM Meet The Team 🔎 Your Deep-Dive Starts Here REBEL Core Cast – Pediatric Respiratory Emergencies: Beyond Viral Season Welcome to the Rebel Core Content Blog, where we delve ... Pediatrics Read More REBEL Core Cast 143.0–Ventilators Part 3: Oxygenation & Ventilation — Mastering the Balance on the Ventilator When you take the airway, you take the wheel and ... Thoracic and Respiratory Read More REBEL Core Cast 142.0–Ventilators Part 2: Simplifying Mechanical Ventilation – Most Common Ventilator Modes Mechanical ventilation can feel overwhelming, especially when faced with a ... Thoracic and Respiratory Read More REBEL Core Cast 141.0–Ventilators Part 1: Simplifying Mechanical Ventilation — Types of Breathes For many medical residents, the ICU can feel like stepping ... Thoracic and Respiratory Read More REBEL Core Cast 140.0: The Power and Limitations of Intraosseous Lines in Emergency Medicine The sicker the patient, the more likely an IO line ... Procedures and Skills Read More REBEL Core Cast 139.0: Pneumothorax Decompression On this episode of the Rebel Core Cast, Swami takes ... Procedures and Skills Read More The post REBEL Core Cast 150.0: Emergency Medicine Consults: How to Call a Consult + Handle Pushback (With Scripts) appeared first on REBEL EM - Emergency Medicine Blog.

EM Pulse Podcast™
Tiny Hot Patients And The PECARN Febrile Infant Rule

EM Pulse Podcast™

Play Episode Listen Later Feb 4, 2026 33:26


This episode of EM Pulse dives into one of the most stressful scenarios in the ED: the febrile infant in the first month of life. Traditionally, a fever in this age group has meant an automatic “full septic workup,” including the dreaded lumbar puncture (LP). But times are changing. We sit down with experts Dr. Nate Kuppermann and Dr. Brett Burstein to discuss a landmark JAMA study that suggests we might finally be able to safely skip the LP in many of our tiniest patients. The Study: A Game Changer for Neonates Our discussion centers on a massive international pooled study evaluating the PECARN Febrile Infant Rule specifically in infants aged 0–28 days. While previous guidelines were conservative due to a lack of data for this specific age bracket, this study provides the evidence we've been waiting for. The Cohort: A large pool of infants across multiple countries. The Findings: The PECARN rule demonstrated an exceptionally high negative predictive value for invasive bacterial infections. The Big Win: The rule missed zero cases of bacterial meningitis. Defining the Danger: SBI vs. IBI The experts break down why we are shifting our terminology and our clinical focus. Serious Bacterial Infection (SBI)  Historically, this was a “catch-all” term including Urinary Tract Infections (UTIs), bacteremia, and meningitis. However, UTIs are generally more common, easily identified via urinalysis, and typically less life-threatening than the other two. Invasive Bacterial Infection (IBI)  This term refers specifically to bacteremia and bacterial meningitis. These are the “high-stakes” infections the PECARN rule is designed to rule out. Dr. Kuppermann notes that we should ideally view bacteremia and meningitis as distinct entities, as the clinical implications of a missed meningitis case are far more severe. The HSV Elephant in the Room One of the primary reasons clinicians hesitate to skip an LP in a neonate is the fear of missing Herpes Simplex Virus (HSV) infection. Low Baseline Risk: While the overall risk of HSV in a febrile infant is low, the risk of “isolated” HSV (meningitis without other signs or symptoms) is even rarer. Screening Tools: Most infants with HSV appear clinically ill. Clinicians can also use ALT (liver function) testing as a secondary screen – transaminase elevation is a common marker for systemic HSV. Clinical Judgment: If the baby is well-appearing, has no maternal history of HSV, no vesicles, and no seizures, the risk of missing HSV by skipping the LP is exceptionally low. Practical Application: Shared Decision-Making This isn’t just about the numbers—it’s about the parents. “Families don’t mind their babies being admitted… They do not want the lumbar puncture. It is the single most anxiety-provoking aspect of care.” — Dr. Brett Burstein The PECARN “Low-Risk” Criteria:  (Remember, this rule applies only to infants who are not ill-appearing.) Urinalysis: Negative Absolute Neutrophil Count (ANC): ≤ 4,000/mm³ Procalcitonin (PCT): ≤ 0.5 ng/mL The Bottom Line: If an infant is well-appearing and meets these criteria, physicians can have a nuanced conversation with parents about the risks and benefits of forgoing the LP, while still admitting the child for observation (often without empiric antibiotics) while cultures brew. Key Takeaways The “Well-Appearing” Filter: If an infant looks ill, the rule does not apply. These patients require a full workup, including an LP, regardless of lab results. Meticulous Physical Exam: Assess for a strong suck, normal muscle tone, brisk capillary refill, and any rashes or vesicles. History is Key: Always ask about maternal GBS/HSV status, pregnancy or birth complications, prematurity, sick contacts, and any changes in feeding, stooling or activity. Procalcitonin: PCT is the superior inflammatory marker for this rule. If your facility only offers traditional markers like CRP, the PECARN negative predictive value cannot be strictly applied. In the words of Dr. Kuppermann: “If you don’t have it, for God’s sakes, just get it! ALT to Screen for HSV: While not part of the official PECARN rule, our experts suggest that significantly elevated liver enzymes should raise suspicion for systemic HSV. Observe, Don’t Discharge: Being “low risk” does not mean the infant goes home. All infants ≤ 28 days still require admission for 24-hour observation and blood/urine cultures. We want to hear from you! Does this change how you approach febrile neonates in the ED? How do you handle shared decision-making with parents? Connect with us on social media @empulsepodcast or on our website ucdavisem.com. Hosts: Dr. Julia Magaña, Professor of Pediatric Emergency Medicine at UC Davis Dr. Sarah Medeiros, Professor of Emergency Medicine at UC Davis Guests: Dr. Nate Kuppermann, Executive Vice President and Chief Academic Officer; Director, Children’s National Research Institute; Department Chair, Pediatrics, George Washington University School of Medicine and Health Sciences Dr. Brett Burstein, Clinician-Scientist and Pediatric Emergency Medicine Physician at Montreal Children’s Hospital, McGill University Resources: Burstein B, Waterfield T, Umana E, Xie J, Kuppermann N. Prediction of Bacteremia and Bacterial Meningitis Among Febrile Infants Aged 28 Days or Younger. JAMA. 2026 Feb 3;335(5):425-433. doi: 10.1001/jama.2025.21454. PMID: 41359314; PMCID: PMC12687207“Hot” Off the Press: Infant Fever Rule “Hot” Off the Press: Infant Fever Rule Do I really need to LP a febrile infant with a UTI? PECARN Infant Fever Update: 61-90 Days Kuppermann N, Dayan PS, Levine DA, Vitale M, Tzimenatos L, Tunik MG, Saunders M, Ruddy RM, Roosevelt G, Rogers AJ, Powell EC, Nigrovic LE, Muenzer J, Linakis JG, Grisanti K, Jaffe DM, Hoyle JD Jr, Greenberg R, Gattu R, Cruz AT, Crain EF, Cohen DM, Brayer A, Borgialli D, Bonsu B, Browne L, Blumberg S, Bennett JE, Atabaki SM, Anders J, Alpern ER, Miller B, Casper TC, Dean JM, Ramilo O, Mahajan P; Febrile Infant Working Group of the Pediatric Emergency Care Applied Research Network (PECARN). A Clinical Prediction Rule to Identify Febrile Infants 60 Days and Younger at Low Risk for Serious Bacterial Infections. JAMA Pediatr. 2019 Apr 1;173(4):342-351. doi: 10.1001/jamapediatrics.2018.5501. PMID: 30776077; PMCID: PMC6450281. Pantell RH, Roberts KB, Adams WG, Dreyer BP, Kuppermann N, O’Leary ST, Okechukwu K, Woods CR Jr; SUBCOMMITTEE ON FEBRILE INFANTS. Evaluation and Management of Well-Appearing Febrile Infants 8 to 60 Days Old. Pediatrics. 2021 Aug;148(2):e2021052228. doi: 10.1542/peds.2021-052228. Epub 2021 Jul 19. Erratum in: Pediatrics. 2021 Nov;148(5):e2021054063. doi: 10.1542/peds.2021-054063. PMID: 34281996. ****Thank you to the UC Davis Department of Emergency Medicine for supporting this podcast and to Orlando Magaña at OM Productions for audio production services.  

Emergency Medicine Cases
Ep 212 PECARN Febrile Young Infant Prediction Tool: When To Safely Forgo LP and Empiric Antibiotics

Emergency Medicine Cases

Play Episode Listen Later Jan 27, 2026 47:36


If you've been practicing EM for more than a decade, your approach to the febrile young infant has (appropriately) evolved. For years, the default was LP + empiric antibiotics + admission for almost everyone. That approach prevented missing meningitis, but at the cost of a lot of harm: invasive testing, unnecessary antibiotics, and hospitalization-related complications. The modern approach is a paradigm shift toward risk stratification, biomarkers, and shared decision-making, while still respecting one immutable truth: Missing neonatal bacterial meningitis can be catastrophic. This episode revisits the framework from a prior EM Cases episode and updates it with a landmark study that directly informs how far we can safely go—especially in the 0–28 day group, with the father of multiple well-known PECARN rules Dr. Nathan Kuppermann and lead author Dr. Brett Burstein...

The Zero to Finals Medical Revision Podcast
Febrile Convulsions (2nd edition)

The Zero to Finals Medical Revision Podcast

Play Episode Listen Later Jan 26, 2026 6:24


This episode covers febrile convulsions.Written notes can be found at https://zerotofinals.com/paediatrics/neurology/febrileconvulsions/Questions can be found at https://members.zerotofinals.com/Books can be found at https://zerotofinals.com/books/The audio in the episode was expertly edited by Harry Watchman.

The Medbullets Step 2 & 3 Podcast
Neurology | Febrile Seizures

The Medbullets Step 2 & 3 Podcast

Play Episode Listen Later Jan 18, 2026 16:00


In this episode, we review the high-yield topic of ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Febrile Seizures⁠⁠ from the Neurology section at ⁠⁠⁠⁠Medbullets.com⁠⁠⁠⁠⁠⁠Follow⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Medbullets⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ on social media:Facebook: www.facebook.com/medbulletsInstagram: www.instagram.com/medbulletsofficialTwitter: www.twitter.com/medbulletsLinkedin: https://www.linkedin.com/company/medbullets

Merriam-Webster's Word of the Day

Merriam-Webster's Word of the Day for January 2, 2026 is: febrile • FEB-ryle • adjective Febrile is a medical term meaning "marked or caused by fever; feverish." It is sometimes used figuratively, as in "a febrile political climate." // I'm finally back on my feet after recovering from a febrile illness. // The actor delivered the monologue with a febrile intensity. See the entry > Examples: "Peppered with exclamation marks, breathless and febrile, this is an utterly mesmeric account of how one man's crimes can affect an entire community." — Laura Wilson, The Guardian (London), 20 June 2025 Did you know? The English language has had the word fever for as long as the language has existed (that is, about a thousand years); the related adjective feverish has been around since the 14th century. But that didn't stop the 17th-century medical reformer Noah Biggs from admonishing physicians to care for their "febrile patients" properly. Biggs apparently thought his medical writing required a word that clearly nodded to a Latin heritage, and called upon the Latin adjective febrilis, from febris, meaning "fever." It's a tradition that English has long kept: look to Latin for words that sound technical or elevated. But fever too comes from febris. It first appeared (albeit with a different spelling) in an Old English translation of a book about the medicinal qualities of various plants. By Biggs's time it had shed all obvious hallmarks of its Latin ancestry. Febrile, meanwhile, continues to be used in medicine in a variety of ways, including in references to such things as "febrile seizures" and "the febrile phase" of an illness. The word has also developed figurative applications matching those of feverish, as in "a febrile atmosphere."

Febrile
124: Fulfilling an Unmet Need - Live from IDWeek 2025!

Febrile

Play Episode Listen Later Nov 3, 2025 26:20 Transcription Available


We are back and live from IDWeek 2025! Drs. Camille Kotton and Roy Chemaly join Febrile to discuss refractory HSV infection in immunocompromised patients!This episode was recorded at an IDWeek 2025 affiliated event in Atlanta, GA on October 20, 2025. Drs. Camille Kotton, Roy Chemaly, and Sara Dong were sponsored speakers by Aicuris Anti-infective Cures AG for this event, however this Febrile content was planned, produced, and reviewed solely by Febrile.Episodes | Consult Notes | Subscribe | Twitter | Merch | febrilepodcast@gmail.comFebrile is produced with support from the Infectious Diseases Society of America (IDSA)

I'm That Mom
Ep 55 - Our Experience with Febrile Seizures

I'm That Mom

Play Episode Listen Later Oct 31, 2025 21:36


Send us a textKaty and Emily wanted to come back to talk about their experience with their little ones having febrile seizures. From the lead up to the event itself, they're walking us through how they handled each situation - and what they learned in case it happens again. Keep up with us on social media!Instagram - @cadenlaneTikTok - @cadenlanebabyFacebook - @cadenlaneCheck out our mom blog:imthatmom.comAnd our store:CadenLane.com

WolverHeme Happy Hour
Chill For 5: The Febrile Neutropenia Survival Guide

WolverHeme Happy Hour

Play Episode Listen Later Oct 9, 2025 49:25


In this episode, Bernie and Anthony review the optimal management of febrile neutropenia! We talk about some historical data, optimal patient workup, proper selection of antibiotics, and a discussion of newer data regarding early antibiotic de-escalation in FN.

Planet Normal
Feeble Starmer is stoking a febrile country

Planet Normal

Play Episode Listen Later Jul 30, 2025 72:29


With Donald Trump giving Starmer a piece of his mind, there's no shortage of madness this week, and your co-pilots are ready to make sense of it all!Allison thinks The US President took the Prime Minister to task on his immigration and green power policies, completely humiliating him on the world stage.Whilst Liam says the ‘febrile atmosphere' in the country isn't being managed very well by Starmer's immigration policies.Stowing away this week is Epping resident Orla Minihine who tells the co-pilots why she is protesting against a local hotel being used to house migrants.Read Allison ‘They tried to break Lucy Connolly, but the decent people of Britain will never desert her':‘https://www.telegraph.co.uk/news/2025/07/29/allison-pearson-lucy-connolly-southport-decent-britain/ |Read more from Allison: https://www.telegraph.co.uk/authors/a/ak-ao/allison-pearson/ |Read Liam ‘I've changed my mind about why Britain has a chronic housing shortage': https://www.telegraph.co.uk/business/2025/07/27/immigration-fuelling-uk-chronic-housing-shortage/ |Read more from Liam: https://www.telegraph.co.uk/authors/liam-halligan/ |Need help subscribing or reviewing? Learn more about podcasts here: https://www.telegraph.co.uk/radio/podcasts/podcast-can-find-best-ones-listen/ |Email: planetnormal@telegraph.co.uk |For 30 days' free access to The Telegraph: https://www.telegraph.co.uk/normal | Hosted on Acast. See acast.com/privacy for more information.

Febrile
120: Gray and Present Danger

Febrile

Play Episode Listen Later May 26, 2025 35:53 Transcription Available


Drs. Sumanth Cherukumilli, Milagritos Tapia, and Adama Mamby Keita join Febrile to describe an approach to a gray membranous pharyngitis!Episodes | Consult Notes | Subscribe | Twitter | Merch | febrilepodcast@gmail.comFebrile is produced with support from the Infectious Diseases Society of America (IDSA)

Mike, Mike, and Oscar
A "Febrile" Cannes Opening - ORC 5/17/25

Mike, Mike, and Oscar

Play Episode Listen Later May 17, 2025 74:25


What is This Episode? - Top of Show . CANNES IS UNDERWAY: DeNiro Hints at Trump Tariff Unrest - 2:24 Mission Impossible Meh - 11:23 . A “Febrile” Reviewing the Reviewers of the In Competition Films - 16:24 The Best Review of 2025, and What's with These Pushes? - 28:11 . GOLDEN GLOBES ADD BEST PODCAST - 38:23 . CONTENDER TRAILERS: The Smashing Machine - 45:47 Weapons - 49:51 Highest 2 Lowest Teaser - 54:31 F1 - 57:44 Materialists - 59:28 Superman Trailer #8000 - 1:01:50 Conjuring Last Rites - 1:06:59 . . WHAT'S NEXT/LEAVE US 5 STARS/WORDS OF WISDOM - 1:09:19

Febrile
118: Below the Belt

Febrile

Play Episode Listen Later Apr 28, 2025 32:23 Transcription Available


Drs. Morgan Hui, Jonathan Darby, Max Olenski, and Catriona Halliday join Febrile from Australia to share a unique case of a transplant recipient with a painless lump.Episodes | Consult Notes | Subscribe | Twitter | Merch | febrilepodcast@gmail.comFebrile is produced with support from the Infectious Diseases Society of America (IDSA)

Emergency Medical Minute
Episode 951: Pediatric Febrile Seizures

Emergency Medical Minute

Play Episode Listen Later Apr 7, 2025 6:40


Contributor: Taylor Lynch, MD Educational Pearls: Pediatric febrile seizures are defined as seizures that occur between the ages of six months to five years in the presence of a fever greater than or equal to 38.0 ºC (100.4 ºF). It is the most common pediatric convulsive disorder, with an incidence between 2-5% What are the types of seizures? Simple: Tonic-clonic seizure, duration

Red Pill Your Healthcast
Q&A: Advanced Endometriosis, Febrile Seizures, Whooping Cough, & Clean Living as a Parent Gallbladder Removal,.

Red Pill Your Healthcast

Play Episode Listen Later Mar 7, 2025 32:27


Connect with the Hosts! Dr. Charlie Website Instagram Membership  Nurse Lauren Website Instagram Email List Amazon StoreFront Membership E-Book on Natural Remedies Check out our website: https://www.redpillyourhealthcast.com/ Welcome back to Red Pill Your Healthcast! Dr. Charlie Fagenholz and Nurse Lauren Johnson are tackling listener-submitted health questions. This week, we dive into: Endometriosis – How diet, lifestyle, and natural remedies can help manage symptoms. Febrile Seizures – Natural approaches to support the body during a fever response. Whooping Cough – The Vitamin C protocol and herbal support for lung health. Gallbladder Removal – How the body responds  and key strategies to support digestion. Clean Living in a Community – How to stay true to a holistic lifestyle while navigating social settings    Supplements + Products Mentioned: All VerVita Supplements Mentioned: Shop All Supreme Supplements Mentioned: Shop Lauren's Fullscript: https://us.fullscript.com/welcome/naturalnursemomma   Dr. Charlie's Fullscript: https://us.fullscript.com/welcome/cfagenholz   —------------------------------ Advanced Endometriomas Artichoke – Shop here: Supports liver and digestion Chaste Tree Supreme – Balances hormones Reducing inflammation through diet and lifestyle Resveratrol from Apex (Shop in Fullscript) – Antioxidant support Japanese Knotweed Supreme – Anti-inflammatory properties Red Infrared Light: Shop Here Emotional Trauma & Healing: Watch Dr. Charlie's Video in Membership EFT Tapping: Learn More Here Find an NET Provider: More Info Castor Oil Packs – Supports detox & circulation SRT Light Therapy: Supports nervous system regulation. Shop Here (Use code DRCHARLIE50 for $50 off) Febrile Seizures Peppermint Oil Epsom Salt Baths – Shop Amazon Homeopathy (Bella Donna) – Shop Amazon The Wet Sock Method: Read This Blog Black Walnut Supreme – Supports microbial balance Scutellaria Supreme – Herbal immune support Acerola Supreme – High in vitamin C VerVita Immune Armor – Immune system support VerVita Matrix Synergy – Cellular health VerVita Elite Harmony Oil – Balances body systems Calcium Lactate by Standard Process: Shop in Fullscript Whooping Cough Vitamin C Protocol: Dr. Suzanne's Guide Astragalus Supreme – Supports lung health Usnea Supreme – Herbal immune support Scutellaria Supreme – Supports respiratory health Takesumi Supreme – Detox support VerVita Elite Harmony – Body balance VerVita Immune Armor  Watch the Deep Dive Vaccine Video in Dr. Charlie's Membership Just the Inserts Informations Here: https://justtheinserts.com/ Our Podcast on Vaccines The Elephant in the Room - Part One - Listen The Elephant in the Room - Part Two - Listen The Elephant in the Room - Part Three - Listen Bringing Food to Family Parties Favorite Snacks (PaleoValley use code DRCHARLIE for 15% off) Gallbladder Removal Watch the Gallbladder Video in Dr. Charlie's Membership Digestive Enzymes (Shop in Fullscript)  Oxfile – Aids liver and bile function Artichoke – Shop here Castor Oil Packs – Promotes circulation & detox

Febrile
114: Season 4 Finale: Match Update & Supporting IMGs in ID

Febrile

Play Episode Listen Later Dec 16, 2024 61:33 Transcription Available


In our Season 4 finale wrapping up 2024, Febrile is excited to host our biggest guest list yet to discuss the importance of International Medical Graduates (IMGs) in infectious diseases! Our guests:Ana Del Valle (Pediatric ID faculty at Arkansas Children's Hospital)Cristina Tomatis (Pediatric ID faculty at Nationwide Children's Hospital)Diego Cruz (Current pediatric resident and recent graduate of pediatric ID fellowship program at Nationwide Children's Hospital)Radhika Sheth (Adult ID faculty at Henry Ford Health System)Shweta Anjan (Adult ID faculty at University of Miami and Jackson Memorial Hospital)Zheyi Teoh (Pediatric ID faculty at Seattle Children's Hospital)Cesar Berto (Adult ID faculty at University of Alabama Birmingham)Episodes | Consult Notes | Subscribe | Twitter | Merch | febrilepodcast@gmail.comFebrile is produced with support from the Infectious Diseases Society of America (IDSA)

Real Talk with Kid Docs
Episode 47. Febrile seizures with Dr. Carey Wilson M.D. Pediatric Neurologist

Real Talk with Kid Docs

Play Episode Listen Later Dec 5, 2024 17:14


Febrile seizures are seizures (abnormal electrical activity in the brain) that occur in the setting of a fever. About 2-5% of all children will experience a febrile seizure in their life. They occur between 6months and 6 years with a peak around 12-18 months of age. Although common and benign, they can be scary- especially the first time your child has one in front of you. What do you do if your child has a seizure? If it was a febrile seizure, will it happen again? Should you pre-medicate for fever?Join us as we welcome Dr. Carey Wilson, M.D. to the show. Dr. Carey Wilson is a Pediatric Neurologist and Epileptologist as well as the Medical Director for the Comprehensive epilepsy clinic at Intermountain Healthcare Primary Children's hospital in Salt Lake City, Utah. I am lucky to say I knew her when she was an intern and have gotten to watch her become an amazing physician and mother. 

Infectious Diseases Society of America Guideline Update
Let's Talk ID x Febrile at IDWeek 2024

Infectious Diseases Society of America Guideline Update

Play Episode Listen Later Nov 5, 2024 32:59 Transcription Available


Recorded onsite at IDWeek 2024 in Los Angeles, the hosts of Let's Talk ID and Febrile discuss what they value most about the conference, including the opportunities to support ID workforce development.

The Dana & Parks Podcast
Febrile Seizures: What are they? Hour 1 9/3/2024

The Dana & Parks Podcast

Play Episode Listen Later Sep 3, 2024 38:56


Febrile Seizures: What are they? Hour 1 9/3/2024 full 2336 Tue, 03 Sep 2024 19:00:03 +0000 F9eNRxQAVA7rWKO15i9hqbtGJLS3E3YT news The Dana & Parks Podcast news Febrile Seizures: What are they? Hour 1 9/3/2024 You wanted it... Now here it is! Listen to each hour of the Dana & Parks Show whenever and wherever you want! 2024 © 2021 Audacy, Inc.

PedsCrit
Invasive Candidiasis with Dr. Paul Sue and Dr. Sara Dong

PedsCrit

Play Episode Listen Later Aug 19, 2024 26:37


Dr. Paul Sue is an associate professor of pediatrics at the Columbia University and Director of the Pediatric Transplant and Immunocompromised Host or “PITCH” Infectious Diseases Program at the Morgan Stanley Children's Hospital in NY.  He completed his pediatric residency at Jacobi Medical Center at the Albert Einstein College of Medicine in the Bronx, and his fellowship in pediatric infectious diseases at Johns Hopkins University in Baltimore. He then moved to UT Southwestern in Dallas TX, where he served as director of Pediatric ICH ID service for the next 8 years, prior to his recent move back to NY.  His research interests include the impact of invasive fungal and viral infections in the immunocompromised host,  leveraging measures of functional immunity to improve infectious disease outcomes in high-risk patients,  and the emergence of community acquired multidrug resistant (MDR) bacterial infections in immunocompromised children. Sara Dong, MD is an adult and pediatric infectious disease physician at Emory University School of Medicine & Children's Healthcare of Atlanta, where her clinical focus is transplant and immunocompromised host ID.  She earned her MD from the Medical University of South Carolina.  She completed her internal medicine and pediatrics (Med-Peds) residency and chief residency years at Ohio State University Wexner Medical Center and Nationwide Children's Hospital, followed by Med-Peds ID and Medical Education fellowships at Beth Israel Deaconess Medical Center and Boston Children's Hospital.  She is the creator and host of Febrile podcast and learning platform, co-host of the ID Puscast podcast, and the program director for the ID Digital Institute.Learning ObjectivesAfter listening to this episode on invasive candidemia, learners should be able to discuss:Treatment of candidemia in a critically-ill immunocompromised patient.Management of indwelling central catheters in critically-ill patients with candidemia.The role of immune adjuncts (e.g. G-CSF or granulocyte transfusions) in the management of persistent candidemia in an immunocompromised patient.References:https://febrilepodcast.com/ Pappas PG, Kauffman CA, Andes DR, Clancy CJ, Marr KA, Ostrosky-Zeichner L, Reboli AC, Schuster MG, Vazquez JA, Walsh TJ, Zaoutis TE, Sobel JD. Clinical Practice Guideline for the Management of Candidiasis: 2016 Update bQuestions, comments or feedback? Please send us a message at this link (leave email address if you would like us to relpy) Thanks! -Alice & ZacSupport the Show.How to support PedsCrit:Please complete our Listener Feedback SurveyPlease rate and review on Spotify and Apple Podcasts!Donations are appreciated @PedsCrit on Venmo , you can also support us by becoming a patron on Patreon. 100% of funds go to supporting the show. Thank you for listening to this episode of PedsCrit. Please remember that all content during this episode is intended for educational and entertainment purposes only. It should not be used as medical advice. The views expressed during this episode by hosts and our guests are their own and do not reflect the official position of their institutions. If you have any comments, suggestions, or feedback-you can email us at pedscritpodcast@gmail.com. Check out http://www.pedscrit.com for detailed show notes. And visit @critpeds on twitter and @pedscrit on instagram for real time show updates.

PedsCrit
Approach to Invasive Fungal Infections in the PICU with Dr. Paul Sue and Dr. Sara Dong

PedsCrit

Play Episode Listen Later Aug 12, 2024 51:11


Dr. Paul Sue is an associate professor of pediatrics at the Columbia University and Director of the Pediatric Transplant and Immunocompromised Host at the Morgan Stanley Children's Hospital in NY.  He completed his pediatric residency at Jacobi Medical Center at the Albert Einstein College of Medicine in the Bronx, and his fellowship in pediatric infectious diseases at Johns Hopkins University in Baltimore. He then moved to UT Southwestern in Dallas TX, where he served as director of Pediatric ICH ID service for the next 8 years, prior to his recent move back to NY.  His research interests include the impact of invasive fungal and viral infections in the immunocompromised host,  leveraging measures of functional immunity to improve infectious disease outcomes in high-risk patients,  and the emergence of community acquired multidrug resistant (MDR) bacterial infections in immunocompromised children. Sara Dong, MD is an adult and pediatric infectious disease physician at Emory University School of Medicine & Children's Healthcare of Atlanta, where her clinical focus is transplant and immunocompromised host ID.  She earned her MD from the Medical University of South Carolina.  She completed her internal medicine and pediatrics (Med-Peds) residency and chief residency years at Ohio State University Wexner Medical Center and Nationwide Children's Hospital, followed by Med-Peds ID and Medical Education fellowships at Beth Israel Deaconess Medical Center and Boston Children's Hospital.  She is the creator and host of Febrile podcast and learning platform, co-host of the ID Puscast podcast, and the program director for the ID Digital Institute.Learning ObjectivesAfter listening to this episode on invasive candidemia, learners should be able to discuss:Risk factors associated with invasive fungal infections in critically-ill immunocompromised patients.Common pathogens associated with invasive fungal infections in critically-ill immunocompromised patients.Principles guiding selection of empiric antifungal agents for critically-ill patients at risk of invasive fungal infections.References:https://febrilepodcast.com/ Pappas PG, Kauffman CA, Andes DR, Clancy CJ, Marr KA, Ostrosky-Zeichner L, Reboli AC, Schuster MG, Vazquez JA, Walsh TJ, Zaoutis TE, Sobel JD. Clinical Practice Guideline for the Management of Candidiasis: 2016 Update by the InfQuestions, comments or feedback? Please send us a message at this link (leave email address if you would like us to relpy) Thanks! -Alice & ZacSupport the Show.How to support PedsCrit:Please complete our Listener Feedback SurveyPlease rate and review on Spotify and Apple Podcasts!Donations are appreciated @PedsCrit on Venmo , you can also support us by becoming a patron on Patreon. 100% of funds go to supporting the show. Thank you for listening to this episode of PedsCrit. Please remember that all content during this episode is intended for educational and entertainment purposes only. It should not be used as medical advice. The views expressed during this episode by hosts and our guests are their own and do not reflect the official position of their institutions. If you have any comments, suggestions, or feedback-you can email us at pedscritpodcast@gmail.com. Check out http://www.pedscrit.com for detailed show notes. And visit @critpeds on twitter and @pedscrit on instagram for real time show updates.

Beyond the Pearls: Cases for Med School, Residency and Beyond (An InsideTheBoards Podcast)

Today's Episode Alexis reviews Case 47 from the Pediatric Morning Report book. A 20-month-old female is brought into the emergency department via ambulance. Her mother had called 911 after the child became unresponsive and exhibited convulsions of her arms and legs. The patient's convulsions stopped after approximately 5 minutes and had ended prior to the arrival of the paramedics. She had developed fever, rhinorrhea, and cough and has been less playful than normal that day. The patient's mother states that her temperature was 103.3°F 1 hour prior to the event. Today's Host Alexis Burnette is a 2nd year medical student at Los Angeles General Medical Center. About Dr. Raj Dr Raj is a quadruple board certified physician and associate professor at the University of Southern California. He was a co-host on the TNT series Chasing the Cure with Ann Curry, a regular on the TV Show The Doctors for the past 7 seasons and has a weekly medical segment on ABC news Los Angeles. More from Dr. Raj www.BeyondThePearls.net The Dr. Raj Podcast Dr. Raj on Twitter Dr. Raj on Instagram Want more board review content? USMLE Step 1 Ad-Free Bundle Crush Step 1 Step 2 Secrets Beyond the Pearls The Dr. Raj Podcast Beyond the Pearls Premium USMLE Step 3 Review MedPrepTGo Step 1 Questions Learn more about your ad choices. Visit megaphone.fm/adchoices

REBEL Cast
REBEL Core Cast 122.0 – Neutropenic Fever

REBEL Cast

Play Episode Listen Later May 15, 2024 8:06


Take Home Points: There are many causes of neutropenia, chemotherapy being by far the most dangerous. Febrile neutropenia is a condition conveying high mortality. Early administration of antibiotics is the only factor known to reduce this mortality. For a patient with neutropenic fever, remember that the body's own flora is the greatest danger. Isolate, but ... Read more The post REBEL Core Cast 122.0 – Neutropenic Fever appeared first on REBEL EM - Emergency Medicine Blog.

PEM Currents: The Pediatric Emergency Medicine Podcast

Febrile Seizures are among the most common neurological problema in young children, occurring in 1 out of 50 children between the ages of 6 months and 5 years of age. This episode of PEM Currents: The Pediatric Emergency Medicine Podcast is a Question and Answer style exploration of some of the most common learning points […]

Albuquerque Fire Rescue Podcast
AFR Case Studies Febrile Seizure

Albuquerque Fire Rescue Podcast

Play Episode Listen Later May 6, 2024 14:36


AFR Case Studies Febrile Seizure by Albuquerque Fire Rescue

Albuquerque Fire Rescue Podcast
AFR Case Studies Febrile Seizure 1

Albuquerque Fire Rescue Podcast

Play Episode Listen Later May 6, 2024 12:14


AFR Case Studies Febrile Seizure 1 by Albuquerque Fire Rescue

Albuquerque Fire Rescue Podcast
AFR Case Studies Febrile Seizure

Albuquerque Fire Rescue Podcast

Play Episode Listen Later May 6, 2024 12:14


AFR Case Studies Febrile Seizure by Albuquerque Fire Rescue

Febrile
97: StAR! Introducing State-of-the-Art Reviews

Febrile

Play Episode Listen Later Apr 15, 2024 17:32 Transcription Available


Drs. Paul Sax, Tara Vijayan, and Allan Tunkel join Febrile to chat about the debut of a new series called “StAR”!! These upcoming episodes will highlight the outstanding Clinical Infectious Diseases (CID) journal State-of-the-Art Reviews (StAR), which cover common clinical topics that ID clinicians encounter. Learn more about the creation of these articles from these CID editors before we kick off 4 back-to-back episodes!!Episodes | Consult Notes | Subscribe | Twitter | Merch | febrilepodcast@gmail.comFebrile is produced with support from the Infectious Diseases Society of America (IDSA)

Infectious Diseases Society of America Guideline Update
Podcasts Killed the Radio Star: Leveraging Digital Education Tools for Modern Learners

Infectious Diseases Society of America Guideline Update

Play Episode Listen Later Apr 13, 2024 31:51


In a new crossover episode with the Febrile podcast, host Buddy Creech, MD, MPH, FPIDS, and Febrile creator and infectious diseases physician, Sara Dong, MD, discuss the power of digital education tools on infectious diseases training.

Febrile
95: Viva Pediatric ID! Live from Memphis

Febrile

Play Episode Listen Later Mar 18, 2024 33:46


Drs. Sumanth Cherukumilli, Emma Mohr, and Paul Spearman join for a live Febrile recording at the St. Jude / PIDS Pediatric Infectious Diseases Research Conference in Memphis, TN. They cover some learning points about early onset neonatal sepsis and chat about career development. Thank you to the conference organizers for the opportunity!Episodes | Consult Notes | Subscribe | Twitter | Merch | febrilepodcast@gmail.comFebrile is produced with support from the Infectious Diseases Society of America (IDSA)

Febrile
88: WAAW with SPIDS - Managing MSSA

Febrile

Play Episode Listen Later Dec 18, 2023 26:03


In collaboration with Saudi Pediatric Infectious Diseases Society and the King Abdulaziz Public Library, Febrile episodes 86-88 are coming to you live from Riyadh!In the last of three episodes, Dr. Rabab Alghaithi and Dr. Meshari Alabdullatif discuss a case of persistent MSSA bacteremiaEpisodes | Consult Notes | Subscribe | Twitter | Merch | febrilepodcast@gmail.com

Febrile
86: WAAW with SPIDS - Deep Dive into DTR Pseudomonas

Febrile

Play Episode Listen Later Dec 4, 2023 21:23


In collaboration with Saudi Pediatric Infectious Diseases Society and the King Abdulaziz Public Library, Febrile episodes 86-88 are coming to you live from Riyadh!In the first of three episodes, listen to Dr. Efteraj Alhowity Dr. Bashayer Alshehail discuss MDR/DTR-Pseudomonas aeruginosa and carbapenemases from a global perspective.Episodes | Consult Notes | Subscribe | Twitter | Merch | febrilepodcast@gmail.com

Febrile
83: Febrile at IDWeek 2023

Febrile

Play Episode Listen Later Oct 23, 2023 41:29


A recap from IDWeek 2023. Check out the guests/correspondents below!Group 1:Dylan Koundakjian, third year internal medicine resident at Emory University, Atlanta, GA (who is applying to ID fellowship!)Jonathan Ryder, Assistant Professor at University of Nebraska Medical Center, Omaha, NE (who is back for this third IDWeek review!)Alainna Jamal, second year internal medicine resident at University of Toronto, Toronto, CanadaCarlyn Harris, fourth year medical student at Emory University, Atlanta, GA (applying to internal medicine and internal medicine primary care)Group 2:Bismarck Bisono-Garcia, second year adult ID fellow at Mayo Clinic, Rochester, MNAnais Ovalle, ID attending and Director of Population Health for internal medicine residents at Kent with Care New England - Brown affiliate, Providence, RIKailynn Jensen, second year medical student at University of Nebraska Medical Center, Omaha, NEBill Wilson, pediatric ID pharmacist specialist at UNC Childrens Hospital, Chapel Hill, NCRaul Macias Gil, ID attending and associate program director for ID fellowship at Harbor UCLA, Los Angeles, CA[and Jonathan Ryder, who was also in Group 1 above]Please check out and sign up for the new IDSA PROUDLY ID Interest Group Community, which Anais, Bill, and Raul mentioned in the episode. This platform is serving to provide a space for LGBTQIA+ advocacy, representation, and education. The link is here: https://docs.google.com/forms/d/e/1FAIpQLSeMtfcT5OOB9akApk-7r7bT9h4MtoL-qDYxhRpBJq06N2R1FA/viewform?usp=sf_linkGroup 3:Rija Alvi, second year adult ID fellow at Henry Ford, Detroit, MI (member of ID Digital Institute)Memar Ayalew, ID clinical pharmacist and co-director of antimicrobial stewardship at Walter Reed Hospital, Washington, DC (member of ID Digital Institute)Radhika Sheth, second year adult ID fellow, Oregon Health Sciences University (OHSU), Portland, OR (member of ID Digital Institute)Julie England, chief medical resident, University of Alabama Birmingham, Birmingham, AL (applying to ID!)Christina Lin, chief medical resident in research at Emory University, Atlanta, GA (applying to ID!)The IDWeek Out-BREAK escape roomPart 1 featured the organizers of the escape room:Victoria Chu, second year pediatric ID fellow, University of California San Francisco, San Francisco, CADiana Zhong, adult ID attending, University of Pittsburgh, ID Connect, Pittsburgh, PAAs well as the other members of the planning committee:Katie Lusardi, ID PharmD, Baptist Health Medical Center, Little Rock, ARJustin Searns, pediatric ID attending at University of Colorado / Children's Hospital of ColoradoJuri Boguniewicz, pediatric ID attending at University of Colorado / Children's Hospital of ColoradoPaul Pottinger, adult ID attending, University of Washington Medical Center, Seattle, WALiz Ristagno, pediatric ID attending, Mayo Clinic, Rochester, MNRachel Wattier, pediatric ID attending, University of California San Francisco, San Francisco, CAAdarsh Bhimraj, adult ID attending, Houston Methodist, Houston, TXNatalie Gabriel, IDSASara Dong, adult and pediatric ID attending at Emory University, Atlanta, GAPart 2 included 2 teams that experienced the escape room:Team 1:Rebecca Kiliany, PharmD, Atrium Health, Charlotte, NCDhananjay Kumar Sinha, nephrologist, Varanasi, Uttar Pradesh,...

Febrile
82: Curious Congenital Conundrums - Pox Puzzle

Febrile

Play Episode Listen Later Oct 9, 2023 34:49


Welcome to Febrile's Curious Congenital Conundrums Part 2!! Drs. Gunjan Mhapankar and Justin Penner discuss approaching a call about a mother of a NICU baby with a new blistering rash.Episodes | Consult Notes | Subscribe | Twitter | Merch | febrilepodcast@gmail.com

Febrile
81: Curious Congenital Conundrums - Dormant Daisy

Febrile

Play Episode Listen Later Oct 2, 2023 29:51


Welcome to Febrile's Curious Congenital Conundrums Part 2!! Drs. Lizzy O'Mahony and Felicity Fitzgerald field a call about persistent fever in a baby boy.Episodes | Consult Notes | Subscribe | Twitter | Merch | febrilepodcast@gmail.com

Febrile
80: Curious Congenital Conundrums - Viral Rival

Febrile

Play Episode Listen Later Sep 25, 2023 38:58


Welcome to Febrile's Curious Congenital Conundrums Part 2!! Drs. Fionnuala Ryan and Alasdair Bamford discuss a NICU consult for neonatal sepsis with hepatosplenomegaly, rash, and elevated ferritinEpisodes | Consult Notes | Subscribe | Twitter | Merch | febrilepodcast@gmail.com

Febrile
79: Curious Congenital Conundrums - Mycobacterial Malady

Febrile

Play Episode Listen Later Sep 18, 2023 34:51


Welcome to Febrile's Curious Congenital Conundrums Part 2!! Drs. Amedine Duret and Liz Whittaker kick off the series with the first episode featuring a mycobacterial malady affecting mother and baby!Episodes | Consult Notes | Subscribe | Twitter | Merch | febrilepodcast@gmail.com

PEM Currents: The Pediatric Emergency Medicine Podcast
Do we need labs or a head CT after simple febrile or unprovoked seizures?

PEM Currents: The Pediatric Emergency Medicine Podcast

Play Episode Listen Later Sep 12, 2023 16:28


Labs or CT scans are not necessary to provide additional diagnostic information or reassurance for most children who recover completely following simple febrile seizures or unprovoked first time generalized seizures. The rate of abnormalities on these studies is very low, and the cost and downsides are too high to justify ordering them on a regular […]

Febrile
77: Pièce de (Gram-negative) Resistance, Part 2: CRE

Febrile

Play Episode Listen Later Jul 10, 2023 33:05


Welcome to Part 2 of this pair of episodes on management of antimicrobial resistant Gram-negative infections!! Drs. Hawra Al-Lawati and Pranita Tamma walk through the alphabet soup of CRE with 2 mini-cases. Don't miss the prior episode (Febrile #76) for more on AmpC and ESBL!You can find the most updated 2023 IDSA Guidance at this link: https://www.idsociety.org/practice-guideline/amr-guidanceEpisodes | Consult Notes | Subscribe | Twitter | Merch | febrilepodcast@gmail.com

The eLife Podcast
Social media and febrile fish

The eLife Podcast

Play Episode Listen Later Jun 6, 2023 36:50


This month we look at a method to raise the bar on the quality and trustworthiness of information shared over social media networks, how fish running a fever heal from infection faster, what miniature bat backpacks can reveal about the eating and hunting habits of our flying mammalian cousins, how kingfishers come by their plumage patterns, and the evolution of spider venom genes. Join Dr Chris Smith for a look inside the science at eLife... Get the references and the transcripts for this programme from the Naked Scientists website

PICU Doc On Call
Integrated PICU Journal Club: An Intubated, Febrile Toddler

PICU Doc On Call

Play Episode Listen Later May 21, 2023 19:55


Today's episode of "PICU Doc On Call," with Dr. Pradip Kamat and Dr. Rahul Damania, pediatric ICU physicians, delves into intriguing case and management strategies within the acute care pediatric setting.This episode focuses on a 2-year-old child transferred to the PICU due to pneumonia-induced respiratory distress. As the child's condition deteriorates, intubation becomes necessary to address acute hypoxemic respiratory failure.We discuss the significance of minimizing unnecessary blood cultures in febrile patients with central lines in the PICU. A study implementing a quality improvement program is referenced, which successfully reduces blood culture rates, broad-spectrum antibiotic usage, and CLABSI rates without impacting mortality or length of stay.Next, we'll explore the comparison between a high-flow nasal cannula (HFNC) and continuous positive airway pressure (CPAP) in pediatric patients experiencing respiratory distress. Findings from a randomized controlled trial revealed that HFNC is non-inferior to CPAP in terms of time required for liberation from respiratory support.We further investigate the application of pediatric early warning scores (PEWS) and automated clinical prediction models to identify patients at risk of deterioration and transfer to the PICU. The importance of employing clinical judgment and a combination of assessment tools to determine the need for transfer is emphasized.Lastly, we'll highlight the significance of screening for social determinants of health in critically ill children and their families. A study demonstrates that a substantial number of participants had unmet social needs, underscoring the importance of screening to provide appropriate interventions and resources.To summarize, this podcast episode covers key topics such as reducing unnecessary blood cultures, comparing HFNC and CPAP in respiratory distress, utilizing PEWS and clinical prediction models for patient identification, and the importance of screening for social determinants of health.Be sure to listen in entirety as we discuss the case.

The Clinical Problem Solvers
Episode 287: RLR – Febrile and Rigid – an episode dedicated to our Rafa Medina

The Clinical Problem Solvers

Play Episode Listen Later May 17, 2023 31:42


RR dedicate this episode to our beloved Rafa Medina.  Rafa's GoFundMe page.