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Warwick Smith of American Pacific Mining connected with MSD's Michael McCrae to discuss the upcoming drill campaign at the Madison copper-gold porphyry project in Montana. Having now received a key drill permit in early October, this next phase of drilling will test large-scale porphyry and high-grade skarn targets with step-outs and deeper holes guided by decades of geologic mapping, geochemical sampling, geophysical surveying, and 3D structural modeling.
Barry Knapp of Ironsides Macro joined MSD today to provide his thoughts on why the last 25 bps cut by the FOMC under-shot the target to save small business, bank and the housing market. Barry also dives into some important data about the weakening labor market and historical data on capex buildout in the current economy.
Mining Stock Daily is thrilled to announce well-known resource reporter, Michael McCrae, is joining MSD as a new correspondent. We welcome Mike into the channel today. We have new drill results to report from Stellar AfricaGold, Intrepid Metals and Aton Resources. Fortuna Mining launch a new JV exploration deal with DeSoto. Both Collective Mining and NexGen announce financings. This episode of Mining Stock Daily is brought to you by... Revival Gold is one of the largest pure gold mine developer operating in the United States. The Company is advancing the Mercur Gold Project in Utah and mine permitting preparations and ongoing exploration at the Beartrack-Arnett Gold Project located in Idaho. Revival Gold is listed on the TSX Venture Exchange under the ticker symbol “RVG” and trades on the OTCQX Market under the ticker symbol “RVLGF”. Learn more about the company at revival-dash-gold.comVizsla Silver is focused on becoming one of the world's largest single-asset silver producers through the exploration and development of the 100% owned Panuco-Copala silver-gold district in Sinaloa, Mexico. The company consolidated this historic district in 2019 and has now completed over 325,000 meters of drilling. The company has the world's largest, undeveloped high-grade silver resource. Learn more at https://vizslasilvercorp.com/Equinox has recently completed the business combination with Calibre Mining to create an Americas-focused diversified gold producer with a portfolio of mines in five countries, anchored by two high-profile, long-life Canadian gold mines, Greenstone and Valentine. Learn more about the business and its operations at equinoxgold.com Integra is a growing precious metals producer in the Great Basin of the Western United States. Integra is focused on demonstrating profitability and operational excellence at its principal operating asset, the Florida Canyon Mine, located in Nevada. In addition, Integra is committed to advancing its flagship development-stage heap leach projects: the past producing DeLamar Project located in southwestern Idaho, and the Nevada North Project located in western Nevada. Learn more about the business and their high industry standards over at integraresources.com
Dr. Monty Pal and Dr. Matteo Lambertini discuss a compelling global study on the clinical behavior of breast cancer in young BRCA1 and BRCA2 carriers, the association of pre-diagnostic awareness of BRCA status with prognosis, and the importance of identifying healthy people who are at risk of carrying the BRCA1/2 pathogenic variants. TRANSCRIPT Dr. Monty Pal: Well, hello everyone, and welcome to the ASCO Daily News Podcast. I'm your host, Dr. Monty Pal. I'm a medical oncologist, professor, and vice chair of medical oncology at the City of Hope Comprehensive Cancer Center in Los Angeles. Now, when we think about genetic testing, whether for patients diagnosed with breast cancer or for other family members of them, it seems to be widely underutilized. Today, we're going to be discussing a recently published study in the Journal of Clinical Oncology that reported on the clinical behavior of breast cancer and specifically young BRCA1 and BRCA2 carriers, and the association of pre-diagnostic awareness of BRCA status with prognosis. I thought this was just a fascinating piece, and I honestly couldn't wait to have this conversation. It's a really compelling paper that highlights the importance of identifying healthy people who are at risk of carrying the BRCA1/2 pathogenic variants, and really the need for genetic counseling and testing to inform people about early detection that could lead to a better prognosis. I'm really delighted to welcome the study's lead author, Dr. Matteo Lambertini. He really needs no introduction. He's very well known in the breast cancer world for his amazing contributions to fertility in the context of breast cancer, to pregnancy in the context of breast cancer, and genetic testing. He's an associate professor at the University of Genova, and a breast cancer medical oncologist at the San Martino Polyclinic Hospital in Genova, Italy. Dr. Lambertini, thank you so much for joining us today. Dr. Matteo Lambertini: Thank you very much, Dr. Pal. It's a great pleasure. Dr. Monty Pal: Oh, thanks. And just FYI, if you're listening in and you want to hear our disclosures, they're all listed at the transcript of this podcast. So, I poured through this paper [Clinical Behavior of Breast Cancer in Young BRCA Carriers and Prediagnostic Awareness of Germline BRCA Status] yesterday, Dr. Lambertini, and first of all, congratulations on this study. This was a huge international multicenter effort, 4,752 patients. How did you pool all these patients with young breast cancer? Dr. Matteo Lambertini: Thanks a lot for the question. Yes, this was an effort made by several centers all over the world. The main idea behind the creation of this network that we have named as BRCA BCY Collaboration, was to get as many data as possible in a sort of niche patient population in the breast cancer field, meaning women diagnosed with breast cancer at the age of 40 years or younger, and all of them being BRCA carriers. We know that around, in the Western world, around 5% of breast cancer cases are being diagnosed under the age of 40 years, and among them around 10-15% are BRCA carriers. So, I would say it's a relatively rare patient population where we did not have a lot of evidence to support our choices in terms of counseling on treatment, prevention, and oncofertility as well. That was the idea behind the creation of this network that includes many centers. Dr. Monty Pal: Yeah. You know, what's so interesting about this is that you sort of draw this line between patients who have BRCA testing at the time of diagnosis and then BRCA testing earlier in their course and then leading to a diagnosis perhaps. And I think that's where really sort of the dichotomy in outcome sits. Can you maybe elaborate on this and tell us about timing of genetic testing in this study and what that meant ultimately in terms of prognosis? Dr. Matteo Lambertini: In this specific analysis from this large network, including almost 5,000 women with breast cancer diagnosed at the age of 40 years or younger and being a BRCA carrier, we looked specifically into the timing of genetic testing because this is a retrospective study and the criteria for inclusion are those that I have just mentioned, so diagnosis at a young age plus carrying germline BRCA pathogenic or likely pathogenic variant. In this analysis, we have looked into the time the patient has got the genetic testing and particular we focused on two populations: those that were diagnosed, knowing already to be a BRCA carrier, and those that got tested after being diagnosed with breast cancer. And the main findings from this analysis have been that knowing to be a BRCA carrier was associated with a lower stage at the time of diagnosis, meaning more T1 tumors, so a tumor less than 2 cm, more node-negative disease, and this translated into less aggressive treatment, so less often axillary dissection, less often use of chemotherapy and anthracycline-based chemotherapy. And even more importantly, we have seen a better overall survival for those patients that were diagnosed already knowing to be BRCA carriers as compared to those tested after breast cancer diagnosis. These results after adjusting for all the confounding, stage, treatment and so on, there was not significant anymore, meaning that it's not the timing of test per se that is probably leading to a better survival, but it is the fact that knowing to be a BRCA carrier would likely translate into having access to all the preventive measures that we have in this setting and this will translate into an overall survival benefit, so in terms of saving more lives in young BRCA carriers. Dr. Monty Pal: I think it's such an important point, and it's one that I think might sound implicit, right, but it needs to be proven, I think, through a study like this. You know, the fact that finding this early, identifying the mutation, doing enhanced screening, and so forth, is really going to lead to superior clinical outcomes. One of the things that I think many people puzzle over, including myself, is what to do? I personally occasionally will see BRCA altered patients in the context of prostate cancer. But that's a very different population of individuals, right? Typically older men. In young females with BRCA mutation, I guess there's a specific set of considerations around reproductive health. You'd already highlighted preventive strategies, but what sorts of things should we be talking about in the clinics once a patient's diagnosed and once perhaps their breast cancer diagnosis is established? Dr. Matteo Lambertini: Yes, exactly. Knowing to be a BRCA carrier has a lot of implications from prevention to treatment to survivorship issues including reproductive counseling. And this is important not only for the patient that has been diagnosed with breast cancer but also for all the family members that will get tested and maybe identify with this sort of genetic alteration before diagnosis of cancer. Why this is important is because we have access to very effective preventive measures, a few examples: MRI screening, which starts at a very young age and normally young women don't have an effective screening strategy outside the BRCA field. Also, primary preventive measures, for example, risk-reducing surgery. These women are known to have a high risk of breast cancer and high risk of ovarian cancer. So the guidelines are suggesting to undergo risk-reducing salpingo-oophorectomy at a young age, so 35 to 40 years in BRCA1 carrier, 40 to 45 years in BRCA2 carrier. And also risk-reducing mastectomy should be discussed because it is a very effective way to prevent the occurrence of breast cancer. And in some situations, including the setting that we are talking about, so young women with breast cancer, BRCA carrier, also risk-reducing mastectomy has shown to improve overall survival. On the other side, once diagnosed with breast cancer, nowadays knowing to be or not a BRCA carrier can make a difference in terms of treatment. We have PARP inhibitors in the early setting, in the adjuvant setting as well as in the metastatic setting. And in terms of survivorship implication, one of the critical aspects for young women is the oncofertility care which is even more complicated when we talk about BRCA carriers that are women candidates for gynecological surgery at a very young age. So this sort of counseling is even more complicated. Dr. Monty Pal: One of the other things, and this is subtle in your paper and I hope you don't mind me bringing it up, is the difference between BRCA1 and BRCA2. It really got me thinking about that because there are differences in phenotype and manifestation. Do you mind just expanding on that a little bit for the audience because I think that's a really important reminder that you brought up in the discussion? Dr. Matteo Lambertini: The difference between BRCA1 and BRCA2 carriers has been known that there are different phenotypes of breast cancer that are more often diagnosed in these two different populations. Normally BRCA1 carriers have a higher likelihood to develop a triple negative breast cancer as compared to BRCA2 carriers, more likely to develop a hormone receptor-positive HER2-negative disease. In this study, again, a specific population of young women with breast cancer, we have seen the same findings, mostly triple negative disease in BRCA1 carrier, mostly luminal-like disease in BRCA2 carrier. But what's novel or interesting from this study is to look also at the age at the time of diagnosis of this disease. And particularly in BRCA1 carriers, we should be sort of more careful about diagnosis of breast cancer and also other primary tumors including ovarian cancer because the risk of developing these malignancies is higher even at a younger age as compared to BRCA2 carriers. And this has implications also in the primary and secondary prevention that we were talking about earlier. Dr. Monty Pal: Oh, interesting. I guess the fundamental question then from your paper becomes, how do we get at the right patients for screening for BRCA1 and BRCA2? And I realize our audience here is largely oncologists who are going to be listening to this podcast, oncology providers, MDs, nurses, etc. But maybe speak for a moment to the general practitioner. Are there things that, for instance, a general practitioner should be looking for to say, “Wait a minute, this patient's high risk, we should consider BRCA1, BRCA2 testing or germline screening”? Dr. Matteo Lambertini: Yes, it's a very important question for the breast cancer community. After the updated ASCO guideline, the counseling is way easier because right now the age cutoff goes up to 65 years, meaning that all the patients diagnosed with breast cancer below the age of 65 years should be tested these days. And then above the age of 65, there are different criteria like triple-negative disease or family history. From a general practitioner standpoint, it's of course a bit more difficult, but knowing particularly the family history of the person that they have in front will be crucial to know if there are cases of breast cancer diagnosed at a young age, maybe triple-negative cases, knowing cases of ovarian cancer in first-degree relatives or pancreatic cancer in first-degree relatives, and of course cases of prostate cancer as well. So, I would say probably mostly the family side will be important from a general practitioner perspective. From an oncology one, the other point that I think is important to stress also based on the data that we have shown in this publication is that having a case of breast cancer known to carry a BRCA pathogenic or likely pathogenic variant. It means that all the people around this case should get tested and if found to be BRCA carrier and healthy carrier, these people should also undergo the primary and secondary prevention strategies because this is very critical also to improve their outcomes and try to avoid the developing of breast or ovarian cancer, but also in the case of diagnosis of this disease, a diagnosis at an earlier stage, as we have seen in this paper. Dr. Monty Pal: Brilliant. I'm going to diverge from our list of questions here and close by asking a question that I have at the top of my mind. You're very young. I know our podcast listeners can't see you, but you're very, very young. Dr. Matteo Lambertini: Thank you. Thank you for that. Not so young but yeah. Dr. Monty Pal: You have nearly 300 papers. Your H-index is 67. You've already made these seminal contributions, as I outlined it from the outset, regarding fertility, regarding use of GnRH analogs, regarding pregnancy and breast cancer. What are you studying now? What are you really excited about right now that you're doing that you think might potentially be practice changing? Give us a little teaser. Dr. Matteo Lambertini: Yeah. Thanks a lot, Dr. Pal. Receiving this compliment from you is fantastic. So, thanks a lot for that. From my side, in terms of my research, I've been interested in the field of breast cancer in young women since the start of my training. I've had very good mentors from Italy, from Europe, from the U.S. I'm still interested in this field, so I think we still have a lot to learn to try to improve the care of young women with breast cancer. For example, the oncofertility care, which is something I worked a lot over the past years. Now with all the new treatment options, there's a sort of new chapter of oncofertility counseling. So, what's the impact of immunotherapy? What's the impact of the new targeted agents? More on the genetic aspects, now we know that there's not only BRCA1 or BRCA2. There are a lot of other different genes that may increase the risk of breast cancer and other malignancies. And also for these genes, we really don't have a lot of evidence to counsel women on prognosis, treatment, prevention strategy. So we need to learn way more for this special patient population that are quite rare, and so we really need a multicenter academic effort to try to give some evidence in this field. Dr. Monty Pal: Yeah. It's tough because these are rare circumstances, but, you know, I think that you've done really well to sort of define some collective experiences that I think really define therapy. I mean, I just remember when I was in training 25 years ago, just reading through textbooks where all the experience around breast cancer and pregnancy was really just very sort of anecdotal almost, you know? And so it's great to see that the state of the science has moved forward. Well, gosh, I really enjoyed our conversation today. I think your study really reminds us how powerful genetic information is in terms of improving outcomes. And, you know, hopefully this will lead some individuals to perhaps test more broadly in appropriate settings. So, thank you so much, Matteo, for joining us today with your fantastic insights on the ASCO Daily News Podcast. Dr. Matteo Lambertini: Thank you very much, Dr. Pal. It's a real pleasure. Dr. Monty Pal: And thanks to our listeners too. You'll find a link to Dr. Lambertini's study in the transcript of this episode. Finally, if you value the insights that you heard today on the ASCO Daily News Podcast, please rate, review, and subscribe wherever you get your podcasts. Thanks a ton. Disclaimer: The purpose of this podcast is to educate and to inform. This is not a substitute for professional medical care and is not intended for use in the diagnosis or treatment of individual conditions. Guests on this podcast express their own opinions, experience, and conclusions. Guest statements on the podcast do not express the opinions of ASCO. The mention of any product, service, organization, activity, or therapy should not be construed as an ASCO endorsement. Find out more about today's speakers: Dr. Sumanta (Monty) Pal @montypal Dr. Matteo Lambertini @matteolambe Follow ASCO on social media: @ASCO on Twitter ASCO on Bluesky ASCO on Facebook ASCO on LinkedIn Disclosures: Dr. Monty Pal: Speakers' Bureau: MJH Life Sciences, IntrisiQ, Peerview Research Funding (Inst.): Exelixis, Merck, Osel, Genentech, Crispr Therapeutics, Adicet Bio, ArsenalBio, Xencor, Miyarsian Pharmaceutical Travel, Accommodations, Expenses: Crispr Therapeutics, Ipsen, Exelixis Dr. Matteo Lambertini: Consulting or Advisory Role: Roche, Novartis, Lilly, AstraZeneca, Pfizer, MSD, Exact Sciences, Gilead Sciences, Seagen, Menarini, Nordic Pharma Speakers' Bureau: Takeda, Roche, Lilly, Novartis, Pfizer, Sandoz, Ipsen, Knight Therapeutics, Libbs, Daiichi Sankyo, Gilead Sciences, AstraZeneca, Menarini, AstraZeneca, Menarini Research Funding (Inst.): Gilead Sciences Travel, Accommodations, Expenses: Gilead Sciences, Daiichi Sankyo Europe GmbH, Roche
Episode 2 of our monthly GU Cast Journal Club and today we focus on two key papers from recent times - the TRANSLATE trial of transperineal vs transrectal biopsy, and Keynote-564 on the role of adjuvant pembrolizomab following nephrectomy. After great feedback from last month's launch episode, we are delighted to welcome back our GU Cast Journal Club Editors, Dr Carlos Delgado (Melbourne, AUS), and Dr Elena Berg (Munich, GER), along with main GU Cast Hosts, Renu Eapen and Declan Murphy Links to papers and previous podcasts below:1. Local anaesthetic transperineal biopsy versus transrectal prostate biopsy in prostate cancer detection (TRANSLATE): a multicentre, randomised, controlled trial Lancet Oncology 2025GU Cast on TRANSLATE 2. Overall Survival with Adjuvant Pembrolizumab in Renal-Cell Carcinoma NEJM 2024GU Cast on K-564 OS paper GU Cast Journal Club is supported by our Partner, MSD, through an unrestricted educational grant.Even better on our YouTube channelAbout GU Cast Journal Club:Each month, two papers are discussed, each of which are of importance to the GU Oncology community. These may be recent papers, or occasionally we will chose a classic landmark paper in GU Oncology. The objective is to draw attention to important papers in GU Oncology, and critique these in a robust manner. The key target audience is trainees working in Urology, Medical Oncology, Radiation Oncology, Nuclear Medicine, and diagnostic specialties such as Radiology and Pathology. But any of our regular audience are likely to enjoy this Journal Club series.
Is drench resistance an issue on your property? Thanks to modern technology, we have tools at our disposal to help.This week's guest is Ryan Luckman, vet and founder of DAGI, (Drench and Grazing Integration), an app that displays the risk of larval challenge/resistance risk for the paddocks on your farm, helping you make better grazing decisions. With the help of industry experts and the support of B+LNZ, Ryan has been building the DAGI (Drench And Grazing Integration) app over the past 2 years. Ryan talks us through the app and how it works on farm, as well as discussing the state of drench resistance in New Zealand. He and Ferg also discuss the topic of refugia and how this is all about the genetics of the worm population on your farm. Take a look at DAGI here:https://www.dagi.nz/why-dagiHead Shepherd is brought to you by neXtgen Agri International Limited. We help livestock farmers get the most out of the genetics they farm with. Get in touch with us if you would like to hear more about how we can help you do what you do best: info@nextgenagri.com.Thanks to our sponsors at MSD Animal Health and Allflex, and Heiniger Australia and New Zealand. Please consider them when making product choices, as they are instrumental in enabling us to bring you this podcast each week.Check out Heiniger's product range HERECheck out the MSD range HERECheck out Allflex products HERE
It's been a busy (and meaningful) stretch for us these past few weeks! In this episode, we take you behind the scenes of our latest adventures across Michigan — from savoring local flavors at the Taste of Generosity event in Royal Oak to celebrating our 20th wedding anniversary (20 years!) at a Detroit Tigers game, complete with accessibility wins at Comerica Park. But our travels didn't stop there. We also traveled to Lansing for MS State Action Day, where we met with lawmakers to advocate for solutions to medical debt, a critical issue for many in the MS community. Additionally, we share updates from our recent neurology appointment in Ann Arbor, including how a small medication adjustment made a significant difference in Dan's sleep and daily life. Join us as we reflect on the power of self-care, the importance of caregiver support, and how embracing each moment keeps us moving forward together. Here are the links we referenced that offer depth and insights for our conversation: • Epic in-state journeys from baseball @ Comerica to lawmakers @ the Capitol – Our blog photo essay that highlights the moments we discuss in this episode. • Episode 84 – Taking on MSd with the Wrong MFR – Link to the podcast episode featuring our conversation with Adam Powell, one of the many friends we a chance meeting with at Taste of Generosity. ***** Remember to rate, review and subscribe to A Couple Takes on MS Podcast for two insightful perspectives on this one multifaceted disease.
Neste programa, olhamos para alguns dos temas que marcaram a semana. Na Guiné-Bissau terminou o prazo para a apresentação de candidaturas às eleições de 23 de Novembro, com a candidatura do PAI-Terra Ranka a ser indeferida por parte do Supremo Tribunal. Domingos Simões Pereira exortou o Supremo Tribunal de Justiça a "corrigir o erro cometido”. Em Angola, cinco organizações da sociedade civil instaram as Nações Unidas a liderarem uma investigação internacional sobre as mortes que ocorreram durante a greve dos taxistas. Em Moçambique, o Presidente da República pediu às Forças de Defesa e Segurança “estratégias para incinerar” o terrorismo. Começamos com a Guiné-Bissau, onde quase duas dezenas de candidaturas foram apresentadas às eleições de 23 de Novembro, de acordo com as intenções divulgadas até ao final do prazo, nesta quinta-feira. O histórico PAIGC corre o risco de, pela primeira vez, ser afastado de eleições, depois de o Supremo Tribunal de Justiça ter rejeitado a candidatura da coligação PAI-Terra Ranka às próximas presidenciais e legislativas da coligação que venceu com maioria absoluta em 2023 e foi afastada do poder com a dissolução do parlamento pelo Presidente, Umaro Sissoco Embaló. Esta sexta-feira, em conferência de imprensa, o líder do PAIGC, Domingos Simões Pereira, exortou o Supremo Tribunal de Justiça a reverter a exclusão da candidatura e a "corrigir o erro cometido”. Na quarta-feira, o candidato presidencial da coligação, Domingos Simões Pereira, falou com a RFI e deixou um aviso: “Ou participamos nestas eleições ou se está a convocar o país para algo de terrível.” Quanto às outras candidaturas, Hugo Correia, em serviço especial para a RFI, fez-nos o resumo. O actual chefe de Estado, Umaro Sissoco Embaló, recandidata-se apoiado pela Plataforma Republicana "Nô Kumpu Guiné", que também viu a candidatura rejeitada, a 16 de Setembro, mas que acabou por ser aprovada depois de corrigidas as irregularidades apontadas pelo Tribunal. O antigo Presidente da Guiné-Bissau José Mário Vaz anunciou que volta a candidatar-se ao cargo, que perdeu para Sissoco Embaló em 2019. José Mário Vaz desvinculou-se do MADEM G-15 e é apoiado pelo COLIDE-GB (Convergência Nacional para a Liberdade e o Desenvolvimento da Guiné-Bissau). Na corrida às eleições, outra coligação, a API Cabas Garandi, que perdeu a maioria dos protagonistas que se tinham juntado em protesto contra o regime do Presidente Embaló. A coligação foi fundada por Braima Camará, depois de o MADEM G-15, que fundou com Sissico Embaló, se ter divido em duas alas, a que apoiava a sua direcção e a que estava com o Presidente da República. O mesmo aconteceu com outro dos fundadores, Fernando Dias, que ficou com uma ala do Partido de Renovação Social (PRS), fiel ao chefe de Estado. Na coligação estava ainda Nuno Gomes Nabiam, antigo primeiro-ministro que, a poucos dias do fim do prazo para a apresentação de candidaturas, deixou a coligação Cabas Garandi e anunciou que volta a concorrer a Presidente da República, apoiado pelo partido que dirige, a Assembleia do Povo Unido - PARTIDO Democrático da Guiné-Bissau (APU-PDGB). Braima Camará foi o primeiro a sair da API Cabas Garandi, depois de ter sido nomeado em agosto primeiro-ministro do Governo de iniciativa presidencial. Fernando Dias, do PRS, avança pela coligação e disse publicamente que nada o impedirá de ser candidato a Presidente da República. Outro membro e deputado do PRS, Siga Batista, entregou também no Supremo Tribunal de Justiça a candidatura às eleições presidenciais. João Bernardo Vieira, ex-secretário de Estado dos Transportes e Comunicações e dirigente do PAIGC, também se candidata à presidência. Nas candidaturas às presidenciais, encontra-se também o antigo primeiro-ministro, Baciro Djá, pela Frente Patriótica para a Salvação Nacional (Frepasna), e o presidente do Partido Aliança para República, Mamado Iaia Djaló. No último dia do prazo, entregaram ainda candidaturas o Partido Movimento Social Democrático (MSD), o Partido do Povo (PDP), o Partido Social dos Trabalhadores (PST), o Partido Unido Social Democrático (PUSD) e o candidato Independente Mamadu Embaló.)) Em Moçambique, os grupos armados em Cabo Delgado, no norte do país, continuam a atacar aldeias, raptar civis e saquear comunidades para sustentar a sua máquina de guerra. O Presidente da República, Daniel Chapo, pediu às Forças de Defesa e Segurança “estratégias para incinerar” os grupos insurgentes. Oiça o trabalho de Orfeu Lisboa, o nosso correspondente. Em Angola, cinco organizações da sociedade civil instaram as Nações Unidas a liderarem uma investigação internacional independente sobre as mortes que ocorreram durante a greve dos taxistas. As ONG´s predispõem-se a fornecer documentação para apoiar a busca por justiça. Francisco Paulo, o nosso correspondente, fez-nos o relato. Angola enfrenta, ha nove meses, um surto de sarampo em larga escala, com um registo de mais de 6 mil casos. Luanda, Uíge, Bié e Lunda-Sul são as regiões mais afectadas devido à falta de cobertura vacinal de rotina. A coordenadora do Programa Nacional de Imunização, Alda de Sousa, admitiu que a falta de cobertura vacinal de rotina para travar esta doença tem contribuído para o aumento de casos. Em Cabo Verde, o sector da Justiça melhorou em 2024, mas continua lento, admitiu o Procurador-Geral da República, Luís Landim. No sector da educação, a primeira-dama, Débora Katisa Carvalho, mostrou-se preocupada com a diminuição de rapazes no sistema de ensino e apelou, também, às famílias para promoverem uma educação mais equitativa e inclusiva, como nos contou Odair Santos. Em São Tomé e Príncipe, escolas em várias localidades estão a registar uma diminuição significativa no número de alunos, contou-nos o nosso correspondente Maximino Carlos. Na cultura, o coreógrafo e bailarino moçambicano Ídio Chichava esteve em destaque na Bienal de Dança de Lyon, em França, considerada como o principal evento de dança contemporânea do mundo. Ídio Chichava apresentou um espectáculo participativo feito com o público e também o espectáculo “Vagabundus”. Oiça aqui.
This episode covers: Cardiology This Week: A concise summary of recent studies Strategic decisions in valvular heart disease Optimising drug therapy in chronic coronary syndromes Mythbusters: Does wearing a white coat make you smarter? Host: Susanna Price Guests: John-Paul Carpenter, Fabien Praz, Robert Storey Want to watch that episode? Go to: https://esc365.escardio.org/event/2092 Want to watch that extended interview on Optimising drug therapy in chronic coronary syndromes ? Go to: https://esc365.escardio.org/event/2092?resource=interview Disclaimer: ESC TV Today is supported by Bristol Myers Squibb and Novartis. This scientific content and opinions expressed in the programme have not been influenced in any way by its sponsors. This programme is intended for health care professionals only and is to be used for educational purposes. The European Society of Cardiology (ESC) does not aim to promote medicinal products nor devices. Any views or opinions expressed are the presenters' own and do not reflect the views of the ESC. The ESC is not liable for any translated content of this video. The English-language always prevails. Declarations of interests: Stephan Achenbach, Yasmina Bououdina, Nicolle Kraenkel, Fabien Praz and Susanna Price have declared to have no potential conflicts of interest to report. Carlos Aguiar has declared to have potential conflicts of interest to report: personal fees for consultancy and/or speaker fees from Abbott, AbbVie, Alnylam, Amgen, AstraZeneca, Bayer, BiAL, Boehringer-Ingelheim, Daiichi-Sankyo, Ferrer, Gilead, GSK, Lilly, Novartis, Pfizer, Sanofi, Servier, Takeda, Tecnimede. John-Paul Carpenter has declared to have potential conflicts of interest to report: stockholder Mycardium AI. Davide Capodanno has declared to have potential conflicts of interest to report: Bristol Myers Squibb, Daiichi Sankyo, Sanofi Aventis, Novo Nordisk, Terumo. Konstantinos Koskinas has declared to have potential conflicts of interest to report: honoraria from MSD, Daiichi Sankyo, Sanofi. Steffen Petersen has declared to have potential conflicts of interest to report: consultancy for Circle Cardiovascular Imaging Inc. Calgary, Alberta, Canada. Robert Storey has declared to have potential conflicts of interest to report: research grants and personal fees from AstraZeneca and Cytosorbents, and personal fees from Abbott, Afortiori Development/Thrombolytic Science, Boehringer Ingelheim/Lilly, Bristol Myers Squibb/Johnson & Johnson, Chiesi, Idorsia/Viatris, Novo Nordisk, PhaseBio and Tabuk. Emma Svennberg has declared to have potential conflicts of interest to report: Abbott, Astra Zeneca, Bayer, Bristol-Myers, Squibb-Pfizer, Johnson & Johnson.
Host: Susanna Price Guest: Robert Storey Want to watch that extended interview? Go to: https://esc365.escardio.org/event/2092?resource=interview Disclaimer: ESC TV Today is supported by Bristol Myers Squibb and Novartis. This scientific content and opinions expressed in the programme have not been influenced in any way by its sponsors. This programme is intended for health care professionals only and is to be used for educational purposes. The European Society of Cardiology (ESC) does not aim to promote medicinal products nor devices. Any views or opinions expressed are the presenters' own and do not reflect the views of the ESC. The ESC is not liable for any translated content of this video. The English-language always prevails. Declarations of interests: Stephan Achenbach, Yasmina Bououdina, Nicolle Kraenkel and Susanna Price have declared to have no potential conflicts of interest to report. Carlos Aguiar has declared to have potential conflicts of interest to report: personal fees for consultancy and/or speaker fees from Abbott, AbbVie, Alnylam, Amgen, AstraZeneca, Bayer, BiAL, Boehringer-Ingelheim, Daiichi-Sankyo, Ferrer, Gilead, GSK, Lilly, Novartis, Pfizer, Sanofi, Servier, Takeda, Tecnimede. John-Paul Carpenter has declared to have potential conflicts of interest to report: stockholder Mycardium AI. Davide Capodanno has declared to have potential conflicts of interest to report: Bristol Myers Squibb, Daiichi Sankyo, Sanofi Aventis, Novo Nordisk, Terumo. Konstantinos Koskinas has declared to have potential conflicts of interest to report: honoraria from MSD, Daiichi Sankyo, Sanofi. Steffen Petersen has declared to have potential conflicts of interest to report: consultancy for Circle Cardiovascular Imaging Inc. Calgary, Alberta, Canada. Robert Storey has declared to have potential conflicts of interest to report: research grants and personal fees from AstraZeneca and Cytosorbents, and personal fees from Abbott, Afortiori Development/Thrombolytic Science, Boehringer Ingelheim/Lilly, Bristol Myers Squibb/Johnson & Johnson, Chiesi, Idorsia/Viatris, Novo Nordisk, PhaseBio and Tabuk. Emma Svennberg has declared to have potential conflicts of interest to report: Abbott, Astra Zeneca, Bayer, Bristol-Myers, Squibb-Pfizer, Johnson & Johnson.
Hedgefund Telemtry's Thomas Thornton joined MSD today for some general market commentary. Tommy discuss the gold move and how he's seeing the charts today as the market provides a little bit of a pullback.
Ben Pullinger of ATEX Resources joined MSD to discuss the updated mineral resource estimate for the Valeriano Project in Chile, which now includes the mineralization from the latest addition of the B2B Zone. The company also announced a new surface rights agreement surrounding the project. Ben talks about the importance of this agreement and what it means for the continued development.
Thousands of you listen to the podcast every week, but we've come to realise many of you don't know exactly what we do here at neXtgen Agri. In this episode, Mark, our host and CEO, takes to the mic and chats about all things neXtgen Agri and the services we provide to farmers across the globe. He shares how “farming in our hearts, science in our heads” drives everything we do.From helping farmers lift genetic gain to building tools that make breeding decisions clearer and faster, Ferg goes through the work that keeps our team busy. We're out in the yards and around kitchen tables across Australia and New Zealand, as well as in meetings and boardrooms for multiple industry bodies, helping provide the knowledge transfer bridge between farmers and scientists.If you have ever wondered what neXtgen Agri is really about, this is the episode that explains it all.Head Shepherd is brought to you by neXtgen Agri International Limited. We help livestock farmers get the most out of the genetics they farm with. Get in touch with us if you would like to hear more about how we can help you do what you do best: info@nextgenagri.com.Thanks to our sponsors at MSD Animal Health and Allflex, and Heiniger Australia and New Zealand. Please consider them when making product choices, as they are instrumental in enabling us to bring you this podcast each week.Check out Heiniger's product range HERECheck out the MSD range HERECheck out Allflex products HERE
Arizona Sonoran Copper's George Ogilvie spoke with MSD last week at the Beaver Creek Precious Metals Summit. He emphasizes the two important catalysts approaching for the Cactus Project in Arizona. First, the company's updated mineral resource estimate (recently published) and then the Preliminary Feasibility Study to follow.
Elemental Altus Royalties and current CEO, Frederick Bell, sits down with MSD to chat about the announced merger with EMX Royalties. The deal is being back by new board members from Tether and will create a new mid-tier royalty company in the mining space. Fred discusses the merging of business strategies and cultures in the new company.
Daniel Earle joined MSD for an introduction to Highlander Silver. Highlander Silver is primarily focused on advancing the bonanza grade San Luis gold-silver project that is located adjacent to the past-producing Pierina mine in Central Peru. San Luis hosts Indicated Mineral Resources of 356 koz Au at 24.4 g/t Au and 8.4 Moz Ag at 579 g/t Ag and ranks among the 10 highest grade projects globally in both gold and silver categories. ** Today, Highlander published those new drill results which were highlighted with 24.8m at 7.43 g/t Au and 16.45 g/t Ag.
Luke Alexander of Newcore Gold joined Trevor at the MSD studio in Beaver Creek to provide some thoughts on the conference. Luke provides some details into the general themes he's saw at the conference along with ideas of questions he received in his meetings.
Our guest this week is Vicky Alexandrou, co-founder of Woven Optics.Over the past eight years, Vicky has helped design and build a handheld microscope that lets you measure wool fibre diameter right there in the yards or shed. Instead of waiting for lab results, you clip a small sample, take a few quick images along the staple, and within seconds, the device tells you the mean micron, standard deviation, coefficient of variation, and comfort factor.You can scan the sheep's ear tag so the data is linked instantly, meaning decisions on classing, culling or breeding can be made on the spot with the most up-to-date information.Vicky and Ferg also chat about the importance of industry collaboration, the current commercialisation of Woven Optics, and the future potential of AI in agriculture.Woven Optics is available now through your local Heiniger representative. Head Shepherd is brought to you by neXtgen Agri International Limited. We help livestock farmers get the most out of the genetics they farm with. Get in touch with us if you would like to hear more about how we can help you do what you do best: info@nextgenagri.com.Thanks to our sponsors at MSD Animal Health and Allflex, and Heiniger Australia and New Zealand. Please consider them when making product choices, as they are instrumental in enabling us to bring you this podcast each week.Check out Heiniger's product range HERECheck out the MSD range HERECheck out Allflex products HERE
Kit Marrs of Alaska Silver, formerly Western Alaska Minerals, provides MSD with a corporate update from the Illinois Creek project in Alaska. Kit talks more about the strategy for its resource estimate in the near future and some thoughts on the gallium mineralization found within its concentrate.
Sandeep Singh, CEO of Western Copper and Gold, provides MSD listeners with a general update on the current process on permitting its Casino project in Yukon.
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What does leadership look like in agriculture today? For Felicity Taylor, Area Manager for Rabobank in Moree and a 2025 Zanda McDonald Award finalist, it's about connection, community and supporting others to succeed.In this episode, Felicity shares her journey from growing up on a cropping property to becoming the youngest area manager in Rabobank's history. She talks about the rising costs facing farming, the challenge for young people to get started, and why she believes regional Australia offers opportunities that city life cannot. Head Shepherd is brought to you by neXtgen Agri International Limited. We help livestock farmers get the most out of the genetics they farm with. Get in touch with us if you would like to hear more about how we can help you do what you do best: info@nextgenagri.com.Thanks to our sponsors at MSD Animal Health and Allflex, and Heiniger Australia and New Zealand. Please consider them when making product choices, as they are instrumental in enabling us to bring you this podcast each week.Check out Heiniger's product range HERECheck out the MSD range HERECheck out Allflex products HERE
Hugh Agro of Revival Gold joins MSD for a walk-through of the latest met test work done on the sulphide mineralization from Beartrack-Arnett. The company has partnered with the GlasLock Process from Dundee Corporate to find improved contrates of gold and a drastic decrease of the arsenic content. Hugh talks about the technology and next steps of the testing process.
What does it take to keep a sheep business moving forward? For our guest this week, Hamish Thomson of Moojepin Merinos, it's a mix of genetics, management and never being afraid to try something new.In the podcast, Hamish talks about the progress they've made since we spoke to him last, which was four years ago! They have been continuing to select for traits like growth, muscle and fat, as well as intensifying the focus to welfare traits such as dag, worms and, more recently, foot structure. He and Ferg also discuss the importance of ewe lamb joining and using ram lambs, containment feeding, and how they are tackling their most unproductive pastures. Twitter: MoojepinMerinosFacebook: MoojepinMerinosHead Shepherd is brought to you by neXtgen Agri International Limited. We help livestock farmers get the most out of the genetics they farm with. Get in touch with us if you would like to hear more about how we can help you do what you do best: info@nextgenagri.com.Thanks to our sponsors at MSD Animal Health and Allflex, and Heiniger Australia and New Zealand. Please consider them when making product choices, as they are instrumental in enabling us to bring you this podcast each week.Check out Heiniger's product range HERECheck out the MSD range HERECheck out Allflex products HERE
Here it is, the first of our new series called GU Cast Journal Club! A dedicated GU Cast Journal Club has been suggested by many of our listeners and viewers over the years, and we are really pleased to kick off today with the first monthly episode. And we are particularly pleased to introduce our GU Cast Journal Club Editors, Dr Carlso Delgado (Melbourne, AUS), and Dr Elena Berg (Munich, GER). Declan Murphy is anchoring today's episode while Renu is busy elsewhere. Each month, two papers will be discussed, each of which are of importance to the GU Oncology community. These may be recent papers, or occasionally we will chose a classic landmark paper in GU OncologyThe objective is to draw attention to important papers in GU Oncology, and critique these in a robust mannerThe key target audience is trainees working in Urology, Medical Oncology, Radiation Oncology, Nuclear Medicine, and diagnostic specialties such as Radiology and Pathology. But any of our regular audience are likely to enjoy this Journal Club series. For this inaugural epsiode, we have selected two very important recent papers:1. Active Surveillance for Screen-detected Low- and Intermediate-risk Prostate Cancer: Extended Follow-up up to 25 Years in the GÖTEBORG-1 Trial 2. Standard or Extended Lymphadenectomy for Muscle-Invasive Bladder Cancer GU Cast Journal Club is supported by our Partner, MSD, through an unrestricted educational grant.
Magna Mining's CEO Jason Jessup joins MSD today for his corporate commentary on this morning's drill results out of the Levack Mine. The company drilled into the R2 system, underneath known mineralization encountered earlier this summer. The results returned high-grade base and precious metals which are moving the stock into new all-time high territory.
Our co-host, Ramona Dallum, is joined by Zonetta English, Project Delivery Director at Louisville MSD. MSD is the regional utility for safe, clean waterways, providing quality wastewater, stormwater, and flood protection services. The duo discusses the current work of the utility, flood response, disaster preparedness, and lessons from Hurricane Katrina.English graduated with a BS in Chemistry from UK and a Masters in Business Administration, Concentration in Management and Finance. She also holds a certificate from the Design Build Institute of America.
Kai Hoffman of Soar Financial joins the MSD airwaves for some spirited commentary on the mining and exploration market. Despite gold mostly flat today, the miners and developers continue to outperform with a few specific equities are breaking out to the upside. We also highlight the Deutsche Goldmesse happening this November in Frankfurt. You can find information about the event HERE.
Ever considered using a drone on your farm? Well, this is the podcast for you. This week, our guest is Luke Chaplain, founder of SkyKelpie. Luke is one of the leading experts in drone mustering in Australia and has spent the last three years researching drone technology to find the best fits for Agricultural use. More recently, Luke has gotten involved in the training of drone usage, to give farmers and other industries the necessary tools for effective drone usage. One of these tools is their latest offering, "SkySim", a simulation to help improve drone piloting skills across all sectors.To find out more about SkyKelpie, you can visit their website here: https://www.skykelpie.com/skysimHead Shepherd is brought to you by neXtgen Agri International Limited. We help livestock farmers get the most out of the genetics they farm with. Get in touch with us if you would like to hear more about how we can help you do what you do best: info@nextgenagri.com.Thanks to our sponsors at MSD Animal Health and Allflex, and Heiniger Australia and New Zealand. Please consider them when making product choices, as they are instrumental in enabling us to bring you this podcast each week.Check out Heiniger's product range HERECheck out the MSD range HERECheck out Allflex products HERE
If you want to know about sheep genetics in New Zealand, our guest this week, John McEwan, is the person to ask. John has been involved with genomics “since before genomics was a thing.”From discovering key reproductive genes and rolling out DNA parentage, to the sequencing of the sheep genome and the industry adoption of genomic selection, John takes us through the milestones that have shaped New Zealand sheep breeding. Tune in today to hear where we're heading next. Head Shepherd is brought to you by neXtgen Agri International Limited. We help livestock farmers get the most out of the genetics they farm with. Get in touch with us if you would like to hear more about how we can help you do what you do best: info@nextgenagri.com.Thanks to our sponsors at MSD Animal Health and Allflex, and Heiniger Australia and New Zealand. Please consider them when making product choices, as they are instrumental in enabling us to bring you this podcast each week.Check out Heiniger's product range HERECheck out the MSD range HERECheck out Allflex products HERE
When you think of a 'modern merino', what comes to mind? For our guest this week, Willera Merino stud principal, Simon Coutts, it means a sheep that works for your business, regardless of the weather or market conditions. Simon explains Willara's breeding philosophy, which focuses on developing a 'modern merino' that is multi-dimensional and provides multiple income streams from high-value wool, prime lamb, capital stock and mutton. Simon and Ferg chat about the three Willera properties and how they work together, as well as the genetic progress they have made by mating ewe lambs and ram lambs. A great insight into a very forward-thinking breeding programme. Willera are having their 2025 ram sale on Friday 29th August”Wadalla” 1072 Old Boort Rd, Bears Lagoon 3517Head Shepherd is brought to you by neXtgen Agri International Limited. We help livestock farmers get the most out of the genetics they farm with. Get in touch with us if you would like to hear more about how we can help you do what you do best: info@nextgenagri.com.Thanks to our sponsors at MSD Animal Health and Allflex, and Heiniger Australia and New Zealand. Please consider them when making product choices, as they are instrumental in enabling us to bring you this podcast each week.Check out Heiniger's product range HERECheck out the MSD range HERECheck out Allflex products HERE
Simon Saunders is one of the original farmers behind Headwaters and runs the elite ewe flock at his farm, Stag Valley. In this episode, he discusses how the breeding program has evolved, what it takes to deliver consistency at scale, and the future of the Lumina lamb programme.If you're wondering how to extract more value from your sheep operation or thinking about speciality lamb production, then this episode is not one to miss! Head Shepherd is brought to you by neXtgen Agri International Limited. We help livestock farmers get the most out of the genetics they farm with. Get in touch with us if you would like to hear more about how we can help you do what you do best: info@nextgenagri.com.Thanks to our sponsors at MSD Animal Health and Allflex, and Heiniger Australia and New Zealand. Please consider them when making product choices, as they are instrumental in enabling us to bring you this podcast each week.Check out Heiniger's product range HERECheck out the MSD range HERECheck out Allflex products HERE
Brock Colterjohn, CEO of Onyx Gold, joins MSD for a walkthrough of the company and their latest drill results coming out of the Argus North target at the Munro-Croesus Project near Timmins, Ontario. Brock walks about the years of work it took the company to consolidate the ground, the process of discovering the Argus North target, and managing the company's equity as a darling of these recent markets in gold exploration.
MSD connects with Brixton Metals once again to discuss their strategic shift towards shallow drilling and a balanced commodity focus. CEO Gary Thompson joins us to discuss the company's approach at the Thorn project, where 50% of the budget targets gold and the other 50% copper. Discover how this strategy is unlocking high-grade mineralization near the surface and what it means for the future of the Camp Creek and Glenfinish zones.
This week, we're chatting about the differences between US and NZ sheep production systems with Dr. Whit Stewart, an Associate Professor and Extension Sheep Specialist in the Department of Animal Science at the University of Wyoming.Whit has spent the last year on a sabbatical in New Zealand, learning and absorbing as much as he can about sheep farming here. Because of this, he has some great insights into the comparisons between systems as well as what we do well, and what we could do better at. He and Ferg chat about predator pressure, grazing public land, the structure of the US lamb supply chain, and what it's like farming in a country where golden eagles can take 40% of your lamb crop. Whit also chats about what he's learnt here in NZ. Our use of tools like FarmIQ, a strong export focus, and top-notch forage management are our strong points, according to Whit. And he also shares what he thinks we could learn from the US in return.It's a great conversation with someone who is very passionate about building better sheep businesses, regardless of where he is on the globe! Head Shepherd is brought to you by neXtgen Agri International Limited. We help livestock farmers get the most out of the genetics they farm with. Get in touch with us if you would like to hear more about how we can help you do what you do best: info@nextgenagri.com.Thanks to our sponsors at MSD Animal Health and Allflex, and Heiniger Australia and New Zealand. Please consider them when making product choices, as they are instrumental in enabling us to bring you this podcast each week.Check out Heiniger's product range HERECheck out the MSD range HERECheck out Allflex products HERE
AI has revolutionized drug discovery by enabling scientists to process vast amounts of historical data, thus accelerating the identification of disease targets and molecule development. AI helps avoid past mistakes and improves the quality of research, making it an indispensable tool in the lab. MSD's approach to AI involves a blend of internal talent and strategic partnerships. By combining computational and web science expertise, MSD ensures that both technological and scientific endpoints are effectively addressed, says Matt Studney, SVP of Research Labs at MSD. Topics addressed: Internal vs. External AI Development at MSD Global Data Management Challenges Generative AI's Impact on Drug Discovery Confidential AI Systems and Documentation Challenges in AI Integration Workforce Upskilling and Cultural Change Future Breakthroughs and Concerns Synthetic Data and Drug Repurposing www.facesofdigitalhealth.com Newsletter: https://fodh.substack.com/ Youtube: https://youtu.be/pgCz-tgHaL0
Isaac Maresky of Gold Hart Copper joins MSD to discuss the first drill result out of the Tolita project in Chile. The hole returned 203.5m of 0.25g/t gold equivalent from 137.5m, including a higher grade zone of 67m at 0.38g/t gold equivalent. Later in this same hole, Gold Hart intercepted another 118m of 0.24g/t gold equivalent, including 45.5m at 0.30g/t gold equivalent. Isaac shares some thoughts on the pending results for the next hole into the project.
This week we're (belatedly) joined by Jack O'Connor, winner of the 2025 Zanda McDonald Award. Jack lives and works on the family's fourth-generation mixed farming operation, Oxton Park, in southern NSW.He and Ferg discuss his career so far and why, for Jack, business success comes down to the people and community he works alongside. And with 20 staff, 15 properties, and both livestock and cropping enterprises, that focus on people is essential!They also chat about the importance of professional development, leadership, and mentorship. It's a great listen for anyone thinking about the future of agriculture and how to bring their team along with them.Head Shepherd is brought to you by neXtgen Agri International Limited. We help livestock farmers get the most out of the genetics they farm with. Get in touch with us if you would like to hear more about how we can help you do what you do best: info@nextgenagri.com.Thanks to our sponsors at MSD Animal Health and Allflex, and Heiniger Australia and New Zealand. Please consider them when making product choices, as they are instrumental in enabling us to bring you this podcast each week.Check out Heiniger's product range HERECheck out the MSD range HERECheck out Allflex products HERE
The Police Minister is defending the focus of a new anti-corruption taskforce. The Serious Fraud Office will aim to understand threats to the public sector. The six-month pilot will be limited to six Government agencies - Inland Revenue, ACC, Corrections, MSD, Land Information NZ, and Sport NZ. Mark Mitchell told Ryan Bridge that globally, some of the biggest recent corruption issues - relate to sporting codes. He wants to ensure there's best practice to maintains the country's low-corruption reputation. LISTEN ABOVESee omnystudio.com/listener for privacy information.
Have you ever felt like a fraud or doubted your accomplishments? In this episode, Kevin welcomes Aoife O'Brien to discuss the often-misunderstood phenomenon of imposter syndrome. Aoife shares research that led her to identify five distinct imposter identities: The Overachiever, The Comparer, The People Pleaser, The Procrastinator, and The Success Fearer, and explains how these behaviors show up and affect individuals and teams. They also talk about how common imposter syndrome is in the workplace, how it can hurt performance and confidence, and how leaders can recognize and support team members who might be struggling. Aoife also introduces her simple ABCDE framework as a practical tool for overcoming imposter thoughts. Listen For 00:00 Intro to Imposter Syndrome 00:30 Welcome to the Remarkable Leadership Podcast 01:25 Kevin introduces his book “Flexible Leadership” 02:10 Introducing Aoife O'Brien 03:00 Aoife's professional journey and inspiration 05:00 Organizational culture and work fulfillment 06:00 Connecting imposter syndrome to workplace happiness 07:00 Aoife's personal imposter syndrome story 08:30 Being featured in a national newspaper 10:00 Defining imposter syndrome 12:00 The impact on individuals and teams 13:00 Imposter syndrome vs. confidence 14:00 How widespread is imposter syndrome? 15:30 Common triggers and barriers 17:00 What leaders can look for in team behavior 18:40 Examples of behavior linked to imposter syndrome 20:00 Real-world feedback from the audience 21:20 Aoife's 5 Imposter Identities 23:15 The Overachiever 23:45 The Comparer 25:20 The People Pleaser 26:15 The Procrastinator 28:00 The Success Feeler 30:00 Aoife's ABCDE Framework 31:00 Acknowledge 31:40 Build Belief 32:30 Courageous Action 33:30 Do It Anyway 34:00 Everyday Practice 35:00 What Aoife does for fun 35:50 What Aoife is reading 36:30 Where to find Aoife online 38:00 Kevin's “Now What?” challenge to listeners Aiofe's Story: Aoife O'Brien founded Happier at Work in 2019 because she witnessed firsthand the impact of poor workplace culture on both organizations and employees. Using her research-based Happier at Work framework, she partners with Global Talent & HR Leaders to cultivate human-centered workplace cultures that prioritize wellbeing, career growth, and meaningful impact. She supports employees to build their confidence, gain career clarity and reach their full potential, while driving increased engagement and retention in organizations. Her clients hire her to speak, train and deliver corporate programs. She has worked with global organizations like Meta, MSD, Ciena, AbbVie, Logitech, and HubSpot. Her award-winning podcast, Happier at Work®, has a global audience of over 125k. This Episode is brought to you by... Flexible Leadership is every leader's guide to greater success in a world of increasing complexity and chaos. Book Recommendations The Happiness Trap (Second Edition): How to Stop Struggling and Start Living by Russ Harris Flexible Leadership: Navigate Uncertainty and Lead with Confidence by Kevin Eikenberry Like this? Love Your Imposter with Rita Clifton Join Our Community If you want to view our live podcast episodes, hear about new releases, or chat with others who enjoy this podcast join one of our communities below. Join the Facebook Group Join the LinkedIn Group Leave a Review If you liked this conversation, we'd be thrilled if you'd let others know by leaving a review on Apple Podcasts. Here's a quick guide for posting a review. Review on Apple: https://remarkablepodcast.com/itunes Podcast Better! Sign up with Libsyn and get up to 2 months free! Use promo code: RLP
We're back on the genetic evaluation theme with Peta Bradley, Operations Manager at Sheep Genetics, to talk all things sheep genetics and the exciting changes that are happening at MLA in terms of bringing the two LAMBPLAN databases together. Peta also discusses the evolution of the Sheep Genetics genetic evaluation over the years, the crucial role of genomics as well as phenotypes and a current reference population, as well as her ice-swimming journey! Head Shepherd is brought to you by neXtgen Agri International Limited. We help livestock farmers get the most out of the genetics they farm with. Get in touch with us if you would like to hear more about how we can help you do what you do best: info@nextgenagri.com.Thanks to our sponsors at MSD Animal Health and Allflex, and Heiniger Australia and New Zealand. Please consider them when making product choices, as they are instrumental in enabling us to bring you this podcast each week.Check out Heiniger's product range HERECheck out the MSD range HERECheck out Allflex products HERE
On the Heather du Plessis-Allan Drive Full Show Podcast for Wednesday, 9 July 2025, Infometrics' Brad Olsen breaks down today's OCR decision and tells Ryan Bridge when we might get another cut to interest rates. The Government is keen to get unemployed job seekers involved in the flood clean-up in Nelson/Tasman. MSD's Craig Churchill tells Ryan so far just six jobseekers have put their hands up. Zoologist professor Philipp Seddon is not a fan of trying to revive the moa and won't hold back on why it's a dumb idea. Plus, the Huddle debates why public servants think half of their co-workers didn't get the job on merit. Get the Heather du Plessis-Allan Drive Full Show Podcast every weekday evening on iHeartRadio, or wherever you get your podcasts. LISTEN ABOVESee omnystudio.com/listener for privacy information.
Tim Coughlin of Royal Road Minerals joins MSD from the Rule Investment Symposium for a breakdown of the exploration work happening throughout their portfolio of jurisdictions.
Vietnam is emerging as one of the fastest-growing pharmaceutical markets in Southeast Asia. Rising healthcare demands, coupled with ongoing policy reforms, are creating exciting new opportunities. However, these developments also present significant challenges that businesses in the industry must navigate. So, what does it take to unlock the full potential of this dynamic and fast-evolving market?Our guest on this week's English edition of Vietnam Innovators is Ms. Katharina Geppert, Managing Director, MSD Vietnam, who has spent over four years living and working in Vietnam. Drawing from her leadership experience across multiple major markets, Ms. Geppert offers valuable insights into MSD's growth strategies, emerging trends in the pharmaceutical industry, and the collaborative opportunities between businesses and policymakers to build a more sustainable healthcare ecosystem for Vietnam.Thank you MSD Vietnam for accompanying Vietnam Innovators. MSD, known as Merck & Co., Inc., Rahway, NJ, USA in the United States and Canada, is one of the premier research-intensive biopharmaceutical companies in the world. With more than 130 years of experience, MSD is at the forefront of research, delivering innovative health solutions that advance the prevention and treatment of diseases in both people and animals. The company fosters a diverse and inclusive global workforce and operate responsibly every day to enable a safe, sustainable and healthy future for all people and communities. For more information, please visit www.msd.com and http://www.msd-vietnam.com; and connect with the MSD team on Twitter, LinkedIn, and YouTube...—Listen to this episode on YouTubeAnd explore many amazing articles about the pioneers at: https://vietcetera.com/vn/bo-suu-tap/vietnam-innovatorFeel free to leave any questions or invitations for business cooperation at hello@vni-digest.com
More than a dozen Ministry of Social Development staff have walked off the job, refusing to return to what they say is an unsafe office with ''strong mould and sewerage smell'. Staff in the ministry's Thames office walked out of the office on Monday, leaving more than 10,000 clients without a face-to-face service. The office was supposed to be a temporary space, after MSD closed its main office in November 2023 due to damage. The Public Service Association has now issued MSD with a Provisional Improvement Notice under the Health and Safety at Work Act, which requires the employer to address concerns about health and safety. MSD has re-deployed staff to Paeroa which is 33km away and has upset community leaders. Thames Community Board chairman Adrian Catran spoke to Lisa Owen.
This episode covers: Cardiology This Week: A concise summary of recent studies Big data in cardiology Measuring lipids: what clinicians need to know Milestones Host: Perry Elliott Guests: Carlos Aguiar, Karim Lekadir, Kostas Koskinas Want to watch that episode? Go to: https://esc365.escardio.org/event/1808 Disclaimer: ESC TV Today is supported by Bristol Myers Squibb and Novartis. This scientific content and opinions expressed in the programme have not been influenced in any way by its sponsors. This programme is intended for health care professionals only and is to be used for educational purposes. The European Society of Cardiology (ESC) does not aim to promote medicinal products nor devices. Any views or opinions expressed are the presenters' own and do not reflect the views of the ESC. The ESC is not liable for any translated content of this video. The English-language always prevails. Declarations of interests: Stephan Achenbach, Nicolle Kraenkel and Karim Lekadir have declared to have no potential conflicts of interest to report. Carlos Aguiar has declared to have potential conflicts of interest to report: personal fees for consultancy and/or speaker fees from Abbott, AbbVie, Alnylam, Amgen, AstraZeneca, Bayer, BiAL, Boehringer-Ingelheim, Daiichi-Sankyo, Ferrer, Gilead, GSK, Lilly, Novartis, Pfizer, Sanofi, Servier, Takeda, Tecnimede. Davide Capodanno has declared to have potential conflicts of interest to report: Bristol Myers Squibb, Daiichi Sankyo, Sanofi Aventis, Novo Nordisk, Terumo. Perry Elliott has declared to have potential conflicts of interest to report: consultancies for Pfizer, BMS, Cytokinetics, AstraZeneca, Forbion. Kostas Koskinas has declared to have potential conflicts of interest to report: speaker fees / honoraria from MSD, Daiichi-Sankyo. Steffen Petersen has declared to have potential conflicts of interest to report: consultancy for Circle Cardiovascular Imaging Inc. Calgary, Alberta, Canada. Emma Svennberg has declared to have potential conflicts of interest to report: Abbott, Astra Zeneca, Bayer, Bristol-Myers, Squibb-Pfizer, Johnson & Johnson.
Join Elevated GP: www.theelevatedgp.com Net32.com Follow @dental_digest_podcast Instagram Follow @dr.melissa_seibert on Instagram As the founder and director of Spear Education, Dr. Spear continues to be recognized as one of the premier educators in esthetic and restorative dentistry in the world today. Dr. Spear earned his dental degree from the University of Washington in 1979, and an MSD in periodontal prosthodontics in 1982, also from the University of Washington. Dr. Spear has been recognized by numerous associations for his contributions to dentistry. In 1993, he was awarded the Christensen Award for Excellence in Restorative Education from the Chicago Dental Society. In 1995, the American Academy of Cosmetic Dentistry presented him with a special award for having advanced the Art and Science of cosmetic dentistry in the United States. In 1996, he received the Saul Schluger Memorial Award for Excellence in Diagnosis and Treatment Planning from the Seattle Study Club. In 2003 he and colleague Vincent G. Kokich were awarded the first ever Presidents Award for excellence in education from the American Academy of Esthetic Dentistry. He also earned the 2004 Distinguished Alumnus Award from Pacific Lutheran University his undergraduate Alma Mater. And in 2013 was named Distinguished Alumnus for the University of Washington School of Dentistry. In 2018 he received the first ever Charles Pincus - Ronald Goldstein Lifetime Achievement Award in Esthetic Dentistry from the American Academy of Esthetic Dentistry. He belongs to multiple dental organizations including the American Academy of Esthetic Dentistry, American Academy of Restorative Dentistry, and the American College of Prosthodontics.
In this episode, host Randy Goruk explores ‘workplace injury prevention' with Dr. Jeff Staheli. Having personally experienced a workplace injury, then practicing in the field of rehabilitation for several years, Dr. Staheli has transitioned to the very important side of injury prevention. Today he trains and educates companies in various industries on how to keep their employees from being hurt at work. He will interactively train you and your team to properly lift, turn, bend, sit and move in any direction. In this episode you will learn: What musculoskeletal disorders (MSDs) are and their impact on workplace safety. Common MSD risks in different work environments. Proper training versus passive training. The importance of shifting from a reactive to a proactive approach to injury prevention. How to create an effective MSD training program that is interactive and job specific. The role of supervisors in identifying and mitigating workplace injury risks. The significant financial costs associated with workplace injuries. Strategies for creating a safety culture that encourages reporting and prevention. The value of ergonomic equipment and proper training in reducing workplace injuries. Practical steps companies can take to start addressing MSD prevention. The potential return on investment for implementing comprehensive injury prevention programs. The bottom line is, don't let your people get hurt; provide effective relavent training, observe, and don't ignore the signs that could lead to life-long pain and suffering. Contact Jeff Staheli on LinkedIn: https://www.linkedin.com/in/jeffstaheli/ Website: https://www.injurypreventionconsultants.com/ Workplace MSD Checklist: https://www.injurypreventionconsultants.com/msd-checklist
Dr. Diane Nicolson of Amarc Resources joins MSD for the first time to provide a general introduction into the company and the three district in BC the company works on. After making a market-moving discovery this winter, the company has recently published results out of their IKE Project.
Join Elevated GP: www.theelevatedgp.com Free Class II Masterclass - Click Here to Join Follow @dental_digest_podcast Instagram Follow @dr.melissa_seibert on Instagram Diego Velásquez, DDS, MSD is a graduate of the Pontificia Universidad Javeriana School of Dentistry, Colombia. He holds certificates in Prosthodontics and Dental Materials, a Master's degree in Science of Dentistry (Indiana University) and a certificate in Periodontics and Dental Implants (The University of Texas Health Science Center at San Antonio). Dr. Velasquez works in private practice in Fenton, Michigan and is an Adjunct Clinical Assistant Professor at the School of Dentistry of The University of Michigan. He is a Diplomate of the American Board of Periodontology and is a member of the peer review panel of the Journal of Periodontology, Clinical Advances in Periodontics, and former consultant of The International Journal of Periodontics and Restorative Dentistry. He is part of the Expert Council of The Osteology Foundation. He is past president of the Midwest Society of Periodontology, Michigan Periodontal Association and The American Academy of Periodontology Foundation.