POPULARITY
Listener discretion is advised. References: Gutierrez, E. (2023). The Vasopressor & Inotrope Handbook: A Practical Guide for Healthcare Professionals. Hu W, Wang X, Su G. Infective endocarditis complicated by embolic events: Pathogenesis and predictors. Clin Cardiol. 2021 Mar;44(3):307-315. doi: 10.1002/clc.23554. Epub 2021 Feb 1. PMID: 33527443; PMCID: PMC7943911. Marik PE, Farkas JD. The Changing Paradigm of Sepsis: Early Diagnosis, Early Antibiotics, Early Pressors, and Early Adjuvant Treatment. Crit Care Med. 2018 Oct;46(10):1690-1692. doi: 10.1097/CCM.0000000000003310. PMID: 30216303.
Interview with Baptiste Jean, MD, author of β-Lactam Inoculum Effect in Methicillin-Susceptible Staphylococcus aureus Infective Endocarditis. Hosted by JAMA Network Open Associate Editor Angel N. Desai, MD, MPH. Related Content: β-Lactam Inoculum Effect in Methicillin-Susceptible Staphylococcus aureus Infective Endocarditis
Who knew that the Duke's criteria could be further modified? In Part 2, Vin and Ruan continue discussing infective endocarditis with the help of skilled cardiologist, Dr Raaesah Bhorat, this time discussing treatment: empiric, targeted and surgical therapy.About our Guest: Dr Raeesa Bhorat is a cardiologist at Sunninghill hospital, working as an interventional fellow under Professor Hellig. She completed her cardiology training at Groote Schuur hospital in 2024; and her interests include structural intervention and research in the application of artificial intelligence to cardiology, particularly the electrocardiogram. She completed her fellowship in internal medicine in 2019 and received her MBChB degree in 2013, cum laude.WE'D LOVE YOUR FEEDBACK ON THIS EPISODE – Visit the Microbe Mail website to sign up for updates Follow on:Instagram: Microbe_MailX/Twitter: @microbemailFacebook: MicrobeMailTiktok: @microbe.mailWatch this episode on our new YouTube channel: Microbe MailE-mail us: mail.microbe@gmail.com
Who knew that the Duke's criteria could be further modified? In this episode, Vin and Ruan explore this update to the criterion and other critical aspects of diagnosing and managing infective endocarditis with the help of skilled cardiologist, Dr Raaesah Bhorat.About our Guest: Dr Raaesah Bhorat is a cardiologist at Sunninghill hospital, working as an interventional fellow under Professor Hellig. She completed her cardiology training at Groote Schuur hospital in 2024; and her interests include structural intervention and research in the application of artificial intelligence to cardiology, particularly the electrocardiogram. She completed her fellowship in internal medicine in 2019 and received her MBChB degree in 2013, cum laudeWE'D LOVE YOUR FEEDBACK ON THIS EPISODE – Visit the Microbe Mail website to sign up for updates Follow on:Instagram: Microbe_MailX/Twitter: @microbemailFacebook: MicrobeMailTiktok: @microbe.mailWatch this episode on our new YouTube channel: Microbe MailE-mail us: mail.microbe@gmail.com
In this episode, Dr Kat Ralston chats with Dr Nik Rae about infective endocarditis. They discuss the complexities of clinical presentation in this condition and share tips to help you in your diagnostic journey. They explore a pragmatic approach to management, including individualised decision making and the emerging evidence base for use of oral agents. Dr Nikolas Rae is a Consultant Physician in Infectious Diseases and Acute Medicine with a range of clinical interests including infections in people who inject drugs, blood borne viruses, mycobacterial and fungal infections. Dr Kat Ralston is a geriatric medicine registrar in Edinburgh. She is also the Education Co-Vice Chair and the joint Podcast Lead for the RCPE Trainee & Members' Committee (T&MC). Recording date: 7 November 2024 -- Useful Links -- Oral vs IV antibiotics systematic review - https://pmc.ncbi.nlm.nih.gov/articles/PMC8901545/ European Society of Cardiology (ESC) Endocarditis Guidelines - https://academic.oup.com/eurheartj/article/44/39/3948/7243107 WikiGuidelines Endocarditis Consensus Statement - https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2807791 Scottish Antimicrobial Prescribing Group (SAPG) penicillin allergy de-labelling guidance - https://www.sapg.scot/guidance-qi-tools/quality-improvement-tools/penicillin-allergy-de-labelling/ -- Follow us -- https://www.instagram.com/rcpedintrainees https://twitter.com/RCPEdinTrainees -- Upcoming RCPE events -- https://events.rcpe.ac.uk/ -- Become an RCPE Member -- https://www.rcpe.ac.uk/membership/join-college Feedback: cme@rcpe.ac.uk
In this episode of MedPOD AFMC, Brig (Dr) J Muthukrishnan hosts Wg Cdr (Dr) Rohit Vashisht, Professor of Medicine and Infectious Disease expert from AFMC, Pune, for an in-depth discussion on infective endocarditis. The episode delves into the clinical presentations, risk factors, and diagnostic challenges of this life-threatening condition. Dr. Vashisht shares insights into identifying complications, understanding microbial etiologies, and the essentials of effective treatment strategies. This episode offers valuable information for healthcare providers managing complex infectious diseases and aiming to improve patient outcomes
Oral health and postoperative infective complications by AORNJournal
Commentary by Dr. Valentin Fuster
Welcome to this high-yield episode on infective endocarditis! Join us as we explore the diagnosis, etiologies, and management of this complex disease. We hope you find this helpful!
Commentary by Dr. Candice Silversides
Commentary by Dr. Valentin Fuster
In this episode we're examining two skin conditions that are frequently presented in general practice, infective folliculitis and pseudofolliculitis barbae. During this episode, we'll explore their distinguishing clinical presentations, dissect their differential diagnoses, and discuss the range of management strategies available for effectively addressing these dermatological conditions. https://skinhealthinstitute.org.au/for-health-professionals/spot-diagnosis/spot-diagnosis-podcast-season-5/See omnystudio.com/listener for privacy information.
CardioNerds (Drs. Amit Goyal, Matthew Delfiner, and Tiffany Dong) discuss infective endocarditis with distinguished clinician-educator Dr. Michael Cullen. We dive into the nuances of infective endocarditis, including native valve endocarditis, prosthetic valve endocarditis, and right-sided endocarditis. Notes were drafted by Dr. Tiffany Dong, and audio editing was performed by student Dr. Adriana Mares. The CardioNerds Beyond the Boards Series was inspired by the Mayo Clinic Cardiovascular Board Review Course and designed in collaboration with the course directors Dr. Amy Pollak, Dr. Jeffrey Geske, and Dr. Michael Cullen. CardioNerds Beyond the Boards SeriesCardioNerds Episode PageCardioNerds AcademyCardionerds Healy Honor Roll CardioNerds Journal ClubSubscribe to The Heartbeat Newsletter!Check out CardioNerds SWAG!Become a CardioNerds Patron! Pearls and Quotes The physical exam is crucial in the evaluation of infective endocarditis and includes cardiac auscultation and a search for sequelae of endocarditis, such as immunologic and embolic phenomena. The modified Duke Criteria categorizes the diagnosis of infective endocarditis into four different buckets: definite endocarditis by pathology, definite endocarditis by clinical criteria, possible endocarditis, and rejected. The diagnosis of endocarditis may involve several different imaging modalities, including transthoracic echocardiogram, transesophageal echocardiogram, 4D CT, and nuclear imaging. For left-sided endocarditis, indications to operate include endocarditis due to S. aureus or fungi, heart failure, evidence of perivalvular complications, persistent bacteremia, and large vegetations. The management of endocarditis often involves multiple teams, including cardiology, infectious disease, addiction medicine, neurology, anesthesiology, and cardiothoracic surgery. Notes What signs/complications of endocarditis are apparent on physical exam and labs? A new or worsening cardiac murmur with possible signs of volume overload. Vascular phenomena encompass splinter hemorrhages, conjunctival hemorrhages, Janeway lesions, mycotic aneurysms, and TIA/strokes. Immunologic phenomena include glomerulonephritis, Roth spots, and Osler nodes. Positive blood cultures with 2-3 samples collected. Elevated inflammatory markers. How does the modified Duke criteria assist in the diagnosis of infective endocarditis? The modified Duke criteria separate the diagnosis of endocarditis into four categories: definite endocarditis by pathology, definite endocarditis by clinical criteria, possible endocarditis, and rejected endocarditis. Definitive endocarditis by pathology requires pathologic confirmation of “bugs under the microscope.” Definitive endocarditis by clinical criteria requires two major criteria, one major and two minor criteria, or all five minor criteria. Possible endocarditis requires one major and one minor or three minor criteria. Major criteria:Positive blood culture for typical organism Evidence of endocardial involvement (e.g., vegetation on echo) Minor CriteriaPredisposing clinical factors (e.g., intravenous drug use, known valvulopathy)FeverImmunologic phenomenaVascular phenomena Blood culture for atypical organism What is the role of TTE compared to TEE in endocarditis? TTE and TEE both have their roles in the workup for endocarditis. TTE can provide a baseline screen and yield a better understanding of ventricular size and function than transesophageal. The strength of TEE is the ability to visualize smaller vegetations along with perivalvular complications that may be missed on TTE. If clinical suspicion is high for endocarditis, repeat echocardiography is warranted. What are other tools to evaluate for endocarditis in prosthetic valves? TTE and TEE remain important and should be commonly utilized for the diagnosis of endocarditis.
In this episode of Heart Matters, Matt Ducsik, Associate Vice President of Clinical Institutes at Providence, is joined by Jim Walsh, MD who specializes in Addiction Recovery Services at Swedish Medical Center in Seattle, Washington, and James Brevig, MD, FACS, a Cardiac and Cardiothoracic Surgeon at Providence Cardiac Surgery in Everett, Washington.Our panel discusses the important topic of how we treat the whole person when caring for cardiac patients, especially those who are poor and vulnerable. In this case, we will be talking about a specific heart condition that disproportionately affects patients with substance use disorder, many of whom are without stable housing or access to other basic health services. Be sure to tune in and listen to the other episodes of Heart Matters or subscribe to have the latest episode delivered to your favorite podcast platform.For more information and resources, visit:ProvidenceProvidence Heart InstituteBoston ScientificMatt Ducsik's LinkedIn
Willow Bioscience CEO Dr Chris Savile joined Steve Darling from Proactive to announce a significant collaboration agreement between Willow Biosciences and SUANFARMA. This partnership is focused on optimizing cell line productivity for manufacturing a high-volume anti-infective Active Pharmaceutical Ingredient (API) using precision fermentation. Savile explained that SUANFARMA will gain access to Willow Biosciences' proprietary strain optimization technologies, enabling the development of a more cost-effective production process for the API. Willow Biosciences will apply its strain engineering technology platform to facilitate cost-effective commercial production of the API at SUANFARMA's manufacturing facility. SUANFARMA is a Contract Development and Manufacturing Organization (CDMO) with a strong track record and expertise in fermentation, purification, and chemical synthesis technologies. Their commitment to maintaining the highest quality standards in pharmaceutical and biotech manufacturing makes them an ideal partner for this collaboration. The agreement reflects both companies' dedication to advancing biotechnology solutions for pharmaceutical production. #proactiveinvestors #willowbioscienceinc #tsx #wllw #otcqb #cansf #bioscience #biotech #invest #investing #investment #investor #stockmarket #stocks #stock #stockmarketnews
Last week, Sarah shared the story of a patient who was finally diagnosed with infective endocarditis after presenting with several symptoms, including fever, tachypnea, chest pain, hypotension and more. In this episode, she'll further explain how the patient was diagnosed and the pathophysiology of this type of infection.Sarah goes over how septic emboli form, and the clinical manifestations that result when they travel in the body as well as the risks and signs of valvular damage to look out for when you've diagnosed infective endocarditis.You'll also learn the areas of the body that can be affected by endocarditis, the diagnostic criteria, and what conditions can predispose a patient to infective endocarditis. Sarah covers the critical role that nurses can play in treating these at-risk patients and how education and compassion can make the biggest difference in the patient's long term outcome.Make sure you're prepared to recognize the signs and symptoms of infective endocarditis and tune into this episode now!Topics discussed in this episode:What predisposes a patient to infective endocarditisWhy and how bacteria starts to formWhat happens after bacteria has invaded the bodyHow endocarditis can lead to dysrhythmiasThe formation of mobile septic emboli and their dangerHow infective endocarditis presents in a patientCommon symptoms of infective endocarditisHow the diagnosis of infective endocarditis is madeThe two treatment options for infective endocarditisThe Nurse's role in caring for this patient populationMentioned in this episode:AND If you are planning to sit for your CCRN and would like to take the Critical Care Academy CCRN prep course you can visit https://www.ccrnacademy.com and use coupon code RAPID10 to get 10% off the cost of the course! Rapid Response and Rescue Intro CourseIf you would like to check out Sarah's 1hr, 1 CE course, go to: http://www.rapidresponseandrescue.com To get the FREE Rapid Response RN Assessment Guide and the coupon code for $10 off the cost of the course, message Sarah on Instagram @TheRapidResponseRN and type the word PODCAST!
In part one of this two part series, our host Sarah Lorenzini shares a story about a patient she was called to see who was under the care of nurse Clayton, a trusted colleague and previous Rapid Response Podcast guest, after he saw a drop in the patient's blood pressure and had a gut feeling something wasn't right. Sarah walks us through her assessment and how the team came to the conclusion that this patient had infective endocarditis.In part two of this series, Sarah will elaborate on this case by explaining how bacteria or fungus grows inside the cardiac muscle, how infective endocarditis presents itself in patients, and the different diagnostic criteria for endocarditis.Topics discussed in this episode:Clayton's concern over a patient's drop in blood pressureSteps Sarah took to assess the patientWhat they found after calling for an expedited echo for the patientWhat is infective endocarditis?Introduction into infective endocarditisMentioned in this episode:AND If you are planning to sit for your CCRN and would like to take the Critical Care Academy CCRN prep course you can visit https://www.ccrnacademy.com and use coupon code RAPID10 to get 10% off the cost of the course! Rapid Response and Rescue Intro CourseIf you would like to check out Sarah's 1hr, 1 CE course, go to: http://www.rapidresponseandrescue.com To get the FREE Rapid Response RN Assessment Guide and the coupon code for $10 off the cost of the course, message Sarah on Instagram @TheRapidResponseRN and type the word PODCAST!
An internist, an infectious disease specialist, and two cardiac surgeons get together to chat about the increasing clinical and ethical conundrum that is infective endocarditis in the setting of patients who inject drugs.
Commentary by Dr. Valentin Fuster
Announcements: The interactive Clinical Pathways have launched and they are available for free! In this episode, Sam Ashoo, MD, and TR Eckler, MD, discuss the March 2023 Emergency Medicine Practice article on Emergency Department Management of Infective Endocarditis-Associated StrokeEpidemiologyPathophysiologyPopulations at RiskComplicationsIntracranial hemorrhageAneurysmsHeart blockPrehospital CareED History and ExaminationImagingAntibiotic TherapySurgical TreatmentSpecial PopulationsSummary
Today we have special guest, Dr. Sarah Gilligan, a nephrologist, to talk about the new study of thiazides for kidney stones. We all learn in medical school that thiazides reduce urinary excretion of calcium, but does that really translate to fewer kidney stones? We also have Dr. Brian Locke on to talk about the CAPE COD trial, a big new critical care paper on using hydrocortisone in severe pneumonia, as well as the latest COPD guidelines and a retrospective study of oral antibiotics for infective endocarditis. Check it out! Hydrochlorothiazide for Kidney StonesSteroids for Pneumonia Meta-analysisHydrocortisone for Severe CAP (CAPE COD)2023 GOLD COPD GuidelinesReal World Use of Oral Antibiotics for EndocarditisMusic from Uppbeat (free for Creators!):https://uppbeat.io/t/soundroll/dopeLicense code: NP8HLP5WKGKXFW2R
This episode covers infective endocarditis.Written notes can be found at https://zerotofinals.com/medicine/cardiology/infectiveendocarditis/ or in the cardiology section of the 2nd edition of the Zero to Finals medicine book.The audio in the episode was expertly edited by Harry Watchman.
Looking for more information on this topic? Check out the Ineffective Endocarditis brick. If you enjoyed this episode, we'd love for you to leave a review on Apple Podcasts. It helps with our visibility, and the more med students (or future med students) listen to the podcast, the more we can provide to the future physicians of the world. Follow USMLE-Rx at: Facebook: www.facebook.com/usmlerx Blog: www.firstaidteam.com Twitter: https://twitter.com/firstaidteam Twitter: https://twitter.com/mesage_hub Instagram: https://www.instagram.com/firstaidteam/ YouTube: www.youtube.com/USMLERX Learn more about Rx Bricks by signing up for a free USMLE-Rx account: www.usmle-rx.com You will get 5 days of full access to our Rx360+ program, including over 800 Rx Bricks. After the 5-day period, you will still be able to access over 150 free bricks, including the entire collections for General Microbiology and Cellular and Molecular Biology.
Episode Notes Episode Notes Inspired by lamentations on Twitter, Drs. Bobbi Jo Stoner (@BobbiJo_Stoner), Jonathan Ryder (@JonathanRyderMD) and Sami El-Dalati join Dr. Jillian Hayes (@thejillianhayes) to hash out some of the controversies we encounter while managing infective endocarditis. Do we really need gentamicin and rifampin for all cases of staphylococcal prosthetic valve endocarditis? Where do oral antimicrobials fit into this disease state? Who should have a seat at the table to provide the most comprehensive care to these patients? Tune in for the answers to these questions and more! Learn more about the Society of Infectious Diseases Pharmacists: https://sidp.org/About Twitter: @SIDPharm (https://twitter.com/SIDPharm) Instagram: @SIDPharm (https://www.instagram.com/sidpharm/) Facebook: https://www.facebook.com/sidprx LinkedIn: https://www.linkedin.com/company/sidp/ Listen to Breakpoints on iTunes, Overcast, Spotify, Listen Notes, Player FM, Pocket Casts, Stitcher, Google Play, TuneIn, Blubrry, RadioPublic, or by using our RSS feed: https://sidp.pinecast.co/ References: IDSA/AHA Infective Endocarditis Guidelines: https://www.ahajournals.org/doi/10.1161/CIR.0000000000000296 Deconstructing the Dogma: Systematic Literature Review and Meta-analysis of Adjunctive Gentamicin and Rifampin in Staphylococcal Prosthetic Valve Endocarditis: https://pubmed.ncbi.nlm.nih.gov/36408468/ Twitter Poll – Gabe Vilchez (March 2021): https://twitter.com/IdVilchez/status/1372148761112240131?s=20&t=fYuyNWGmzZACWrpUb7Fp3g Survey of ID Physicians on Gent and Rifampin Use: https://pubmed.ncbi.nlm.nih.gov/32964063/ Bacteriological outcome of combination versus single-agent treatment for staphylococcal endocarditis: https://academic.oup.com/jac/article/52/5/820/760105 Treatment of experimental foreign body infection caused by methicillin-resistant Staphylococcus aureus: https://journals.asm.org/doi/abs/10.1128/AAC.34.12.2312 Successful therapy of experimental chronic foreign-body infection due to methicillin-resistant Staphylococcus aureus by antimicrobial combinations: https://journals.asm.org/doi/abs/10.1128/aac.35.12.2611 Rifampin Combination Therapy for Nonmycobacterial Infections: https://journals.asm.org/doi/10.1128/CMR.00034-09 ARREST Trial: https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(17)32456-X/fulltext Is Rifampin Use Associated With Better Outcome in Staphylococcal Prosthetic Valve Endocarditis? A Multicenter Retrospective Study: https://pubmed.ncbi.nlm.nih.gov/32706879/ Nephrotoxicity of vancomycin, alone and with an aminoglycoside: https://pubmed.ncbi.nlm.nih.gov/2351627/ Clinical Data on Daptomycin plus Ceftaroline versus Standard of Care Monotherapy in the Treatment of Methicillin-Resistant Staphylococcus aureus Bacteremia: https://journals.asm.org/doi/10.1128/AAC.02483-18 Multicenter Cohort of Patients With Methicillin-Resistant Staphylococcus aureus Bacteremia Receiving Daptomycin Plus Ceftaroline Compared With Other MRSA Treatments: https://academic.oup.com/ofid/article/7/1/ofz538/5691187 CERT Trial (in process): https://clinicaltrials.gov/ct2/show/NCT04886284 Rifampin for Surgically Treated Staphylococcal Infective Endocarditis: A Propensity Score-Adjusted Cohort Study: https://pubmed.ncbi.nlm.nih.gov/26872729/ A step-by-step guide to implementing a multidisciplinary endocarditis team: https://journals.sagepub.com/doi/10.1177/20499361211065596 Management of Infective Endocarditis in People Who Inject Drugs: A Scientific Statement from the American Heart Association: https://www.ahajournals.org/doi/10.1161/CIR.0000000000001090?cookieSet=1 Infectious Complications of Addiction: A Call for a New Subspecialty Within Infectious Diseases: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7319263/ A Cross-sectional Analysis of Linezolid in Combination with Methadone or Buprenorphine as a Cause of Serotonin Toxicity: https://academic.oup.com/ofid/article/9/7/ofac331/6625822 POET Trial: https://www.nejm.org/doi/full/10.1056/nejmoa1808312 Risk of New Bloodstream Infections and Mortality Among People Who Inject Drugs With Infective Endocarditis: https://pubmed.ncbi.nlm.nih.gov/32785635/ Comparing right- and left sided injection-drug related infective endocarditis: https://pubmed.ncbi.nlm.nih.gov/33441950/ Evaluation of Partial Oral Antibiotic Treatment for Persons Who Inject Drugs and Are Hospitalized With Invasive Infections: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7745005/ Dalbavancin as Primary and Sequential Treatment for Gram-Positive Infective Endocarditis: 2-Year Experience at the General Hospital of Vienna: https://pubmed.ncbi.nlm.nih.gov/29659732/ Impact of the duration of antibiotic therapy on relapse and survival following surgery for active infective endocarditis: https://academic.oup.com/ejcts/article/55/4/760/5126415 Bacteriological Outcome after Valve Surgery for Active Infective Endocarditis: Implications for Duration of Treatment after Surgery: https://academic.oup.com/cid/article/41/2/187/529954 Long-term Risk of Hemorrhagic Stroke in Patients With Infective Endocarditis: A Danish Nationwide Cohort Study: https://academic.oup.com/cid/article/68/4/668/5039147 Sign of the Times: Updating Infective Endocarditis Diagnostic Criteria to Recognize Enterococcus faecalis as a Typical Endocarditis Bacterium: https://pubmed.ncbi.nlm.nih.gov/35262664/ Prevalence of colorectal disease in Enterococcus faecalis infective endocarditis: results of an observational multicenter study: https://pubmed.ncbi.nlm.nih.gov/31444092/ Check out our podcast host, Pinecast. Start your own podcast for free with no credit card required. If you decide to upgrade, use coupon code r-7e7a98 for 40% off for 4 months, and support Breakpoints.
Deion Sanders or "Prime Time" is one of the greatest Defensive Backs to ever play in the National Football League (NFL). In fact, he was inducted into the NFL Hall of Fame in 2011. In addition to being a professional American Football player, Deion Sanders also put in a respectable career in Major League Baseball (MLB).But that's not why we're here today. Instead, we're going to focus on Deion Sanders' (now Coach Prime) positive impact on Jackson State University and the coaches, staff, and players there. Coach Prime leads from the front in the show of the same name on Amazon Prime.Coach Prime's statement, "Are you effective or infective?", the title of this episode, comes from the last episode of the series where Coach Prime puts a vote up to this team and coaching staff to help deal with someone spreading negative vibes throughout the Jackson State University football family.So, hit play and hear more about how this decision went and how we can all benefit from asking ourselves, "Am I being effective or infective?" when leading or part of sports, project, or public safety teams.Remember...Have a plan to keep teams in syncStay informed with facts, not fearGet involved so you can make a differenceGodspeed,Kevin
This episode features Dr. Shaefer Spires from DASON and Dr. Reinaldo (Rey) Perez from Duke Infectious Diseases. The article reviewed in this episode is available here: https://doi.org/10.1186/s12879-021-06391-2. For more information about DASON, please visit: https://dason.medicine.duke.edu. Find out more at https://dason-digest.pinecast.co
In this episode, we have Dr. Malika Sharma, Infectious Diseases physician take us through the 2015 Guidelines to the diagnosis, treatment and management of endocarditis. We also include some of the new 2020 updates as well! Host: Dr. Sheliza Halani (Internal Medicine Resident)Sound Editing: Alison LaiProduced by: Dr. Sheliza Halani and Dr. Catherine LeurerSupport the show
Commentary by Dr. Valentin Fuster
Commentary by Dr. Valentin Fuster
In this episode, we have Dr. Malika Sharma, Infectious Diseases physician take us through the 2015 Guidelines to the diagnosis, treatment and management of endocarditis. We also include some of the new 2020 updates as well! Host: Dr. Sheliza Halani (Internal Medicine Resident)Sound Editing: Alison LaiProduced by: Dr. Sheliza Halani and Dr. Catherine Leurer
This week, Rob and Zach will be teaching you everything you need to know about Infective Endocarditis.We will be discussing:Definition of Infective EndocarditisCausesPathophysiologyClinical FeaturesPhysical Exam FindingsDiagnosisTreatmentPreventionTo follow along with Notes & Illustrations for our podcasts please become a member on our website! https://www.ninjanerd.orgwww.ninjanerd.org/podcast/infective-endocarditisFollow us on:YouTube: https://www.youtube.com/ninjanerdscienceInstagram: https://www.instagram.com/ninjanerdlecturesFacebook: https://www.facebook.com/NinjaNerdLecturesTwitter: https://twitter.com/ninjanerdsciDiscord: https://discord.com/invite/3srTG4dngWTikTok: https://www.tiktok.com/@ninjanerdlecturesSupport the show (https://paypal.me/ninjanerdscience)
Contributor: Jared Scott, MD Educational Pearls: Variability of organisms in infecting the myocardial valves Duke Criteria for Infective Endocarditis includes three categories that can be used to definitively diagnose endocarditis Pathologic Criteria pathological evidence of infection Major Clinical Criteria positive blood cultures positive echocardiogram findings (TEE is more sensitive than a TTE) Minor Clinical Criteria (must include all of the below criteria) Fever Underlying heart condition or IV drug use Vascular phenomena (includes Janeway's lesions) Immunologic phenomena (includes Osler's nodes, Roth spots) Positive blood cultures or serologic evidence of infection with bacteria known to cause endocarditis Some studies show up to a 33% one-year mortality of people diagnosed with endocarditis This criteria was developed by David Durack, MD and he was affiliated with Duke University, shout out to Dr. Pete Bakes! References https://www.mdcalc.com/duke-criteria-infective-endocarditis https://www.youtube.com/watch?v=3NLtNg-pqv0 Holland TL, Baddour LM, Bayer AS, Hoen B, Miro JM, Fowler VG Jr. Infective endocarditis. Nat Rev Dis Primers. 2016;2:16059. Published 2016 Sep 1. doi:10.1038/nrdp.2016.59 Summarized by John Spartz, MS4 | Edited by Erik Verzemnieks, MD The Emergency Medical Minute is excited to announce that we are now offering AMA PRA Category 1 credits™ via online course modules. To access these and for more information, visit our website at https://emergencymedicalminute.org/cme-courses/ and create an account. Donate to EMM today!
Commentary by Dr. Valentin Fuster
Role of Imaging in Known or Suspected Infective Endocarditis Guest: Michael W. Cullen, M.D. (@mwcullen) Host: Paul A. Friedman, M.D. (@drpaulfriedman) The diagnosis and treatment of patients with infective endocarditis can be complex. Successful outcomes require multidisciplinary support for imaging, management and therapy. Joining us today to discuss the use of imaging in the initial evaluation and management of infective endocarditis is Michael W. Cullen, M.D., a cardiologist and expert echocardiographer at Mayo Clinic in Rochester, Minnesota. Specific topics discussed: Risk factors, signs and symptoms that raise the suspicion of infective endocarditis Comprehensive physical examinations necessary for diagnosis Hospitalization, blood cultures and antibiotics required for evaluation Imaging types and considerations for use Potential complications and their diagnosis Role of imaging in the management of infective endocarditis Surveillance imaging and follow-up Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV. NEW Cardiovascular Education App: The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today! No CME credit offered for this episode. Podcast episode transcript found here.
Commentary by Dr. Julia Grapsa
Master endocarditis! Don't feel thwarted by a positive set of blood cultures. We're joined by Dr. David Serota (@serotavirus) for a comprehensive discussion of the pathophysiology of infective endocarditis, frameworks for work-up and diagnosis, the TTE vs. TEE debate, indications for valve surgery, antibiotic tips, harm reduction strategies, and more! Claim free CME for this episode at curbsiders.vcuhealth.org! Episodes | Subscribe | Spotify | Swag! | Top Picks | Mailing List | thecurbsiders@gmail.com | Free CME! Credits Writer and Producer: Adam Barelski MD Show Notes: Beth Garbitelli; Adam Barelski MD Infographic: Adam Barelski MD Hosts: Matthew Watto MD, FACP; Paul Williams MD, FACP, Adam Barelski MD Reviewer: Meredith Trubitt, MD Executive Producer, Cover Art: Beth Garbitelli Showrunner: Matthew Watto MD, FACP Editor: Clair Morgan of nodderly.com Guest: David Serota MD Sponsor: Imperfect Foods Right now, Imperfect Foods is offering our listeners 20% off your first 4 orders when you go to https://www.imperfectfoods.com and use promo code CURB. Sponsor: Southern California Permanente Medical Group Want to make a difference in a community that appreciates your passion and expertise? Then join SCPMG as an Outpatient Internal Medicine Physician. Learn more or apply at scpmgphysiciancareers.com or call (866) 449-1684. Sponsor: P3 P3 is a revenue cycle management provider that takes over your workload for claim submissions, and denial management. P3 is offering a 10% discount on all invoices for a limited time period. Visit www.p3care.com/curb and avail your offer today! CME Partner: VCU Health CE The Curbsiders are partnering with VCU Health Continuing Education to offer FREE continuing education credits for physicians and other healthcare professionals. Visit curbsiders.vcuhealth.org and search for this episode to claim credit. Show Segments Intro, disclaimer, guest bio Guest one-liner, Picks of the Week* Case from Kashlak; Definitions What to do with positive blood cultures Initial workup for endocarditis How to diagnose endocarditis When to get a TTE and a TEE Indications for valve surgery Antibiotic tips Oral vs IV antibiotics Treatment considerations for patients who inject drugs Take-home points Outro
Dr. Jason Goodchild, Vice President of Clinical Affairs at Premier Dental Products Company, and Dr. Mark Donaldson, Associate Principal in Pharmacy Advisory Solutions at Vizient discuss the merits of a recent statement on antibiotic prophylaxis for infective endocarditis with host Gretchen Brummel. Guest speakers: Jason Goodchild, DMD Vice President of Clinical Affairs Premier Dental Products Company Mark Donaldson, BSP, ACPR, PHARMD, FASHP, FACHE Associate Principal, Pharmacy Advisory Solutions Vizient Moderator: Gretchen Brummel, PharmD, BCPS Pharmacy Executive Director Vizient Center for Pharmacy Practice Excellence Show Notes: [00:53-1:55] Antibiotic prophylaxis against infective endocarditis as an important tool [01:56-2:48] Risks of over- or underutilization of this treatment modality [02:49-4:52] History of the guidelines [04:53-5:48] New statement impacts moving forward [05:49-8:49] Doxycycline as alternative to clindamycin in penicillin-allergic patients [08:50-9:47] The rationale to abandon clindamycin [09:48-11:49] How clindamycin compares to other agents [11:50-12:59] The bottom line Links | Resources: Prevention of Viridans group Streptococcal infective endocarditis: a scientific statement from the American Heart Association: Click here Prevention of infective endocarditis: guidelines from the American Heart Association: Click here Antibiotic prophylaxis guidelines: is there new information for 2021? Click here Subscribe Today! Apple Podcasts Amazon Podcasts Google Podcasts Spotify Stitcher Android RSS Feed
In this episode Jame and Callum discuss Infective Endocarditis. In this 2nd of two episodes on this topic we discuss the: severity assessment, indications for surgery, treatment options by organism and innovations in practice. Send suggestions to idiotspodcasting@gmail.com
In this episode Jame and Callum discuss Infective Endocarditis. In this 1st of two episodes on this topic we discuss the: definition, causative organisms, risk factors, symptoms/signs; diagnostics; and the Duke's criteria Send suggestions to idiotspodcasting@gmail.com
This episode talks about etiopathogenesis of Infective Endocarditis, modified Duke's Criteria, Symptoms and Signs of IE, Complications, Investigations and Management of the disease.
Commentary by Dr. Julia Grapsa
Today we'll be covering Infective Endocarditis, going along with this month's theme, Infectious Disease- Chest Infections. If you haven't listened to our podcast before, each week we have a case-based discussion about a medical topic to help you study for the pediatric medicine board exam. Episodes are released every weekend, and the case is then reviewed and reinforced on social media throughout the week. Follow the podcast on social media: Facebook- @portablepeds (www.facebook.com/portablepeds) Twitter- @portablepeds (www.twitter.com/portablepeds) We'd love to hear from you via email at portablepeds@gmail.com! Also, feel free to visit our website, www.portablepeds.com, for more content. Today's Case: A previously healthy 7 year old male was admitted to the ICU following a TBI. A PICC line was placed as part of his therapy. As he recovers, he develops persistent fevers, arthralgias, and malaise. On exam, a new heart murmur is noted. His blood cultures are positive, and due to the new heart murmur, an echocardiogram is obtained. The echocardiogram demonstrates a new endocardial vegetation confirming the diagnosis of infective endocarditis. Which organism is most likely growing in his blood cultures? An Enterococcus species Viridans group Streptococci Staphylococcus aureus Coagulase negative Staphylococci A Salmonella species We would like to give an enormous thank you to Zack Goldmann for designing this podcast's logo and accompanying artwork. You can find more of his work at www.zackgoldmann.com. The intro and outro of this podcast is a public domain song obtained from scottholmesmusic.com. Intro/Outro- Hotshot by Scott Holmes Disclaimer: This podcast is intended for healthcare professionals. The information presented is for general educational purposes only and should NOT be used as professional medical advice or for the diagnosis or treatment of medical conditions. The views and opinions expressed do not represent the views and opinions of our employer or any affiliated institution. Expressed opinions are based on specific facts, under certain conditions, and subject to certain assumptions and should not be used or relied upon for any other purpose, including, but not limited to, the diagnosis or treatment of medical conditions or in any legal proceeding. Full terms and conditions can be found at portablepeds.com. Thanks for listening! As always, please Rate and Review this podcast on Apple Podcasts, Facebook, or your favorite podcasting platform. Also, Subscribe to get all the latest episodes, and Share this episode with someone you think would enjoy it! Hope to see you real soon!
Commentary by Dr. Valentin Fuster
Kyle Wamsley, Pharm.D. (@KyleWamsley1) discusses current literature surrounding the use of oral antimicrobials in the treatment of infective endocarditis (IE), identifies specific patient populations in whom it may be appropriate to consider oral therapy for the treatment of IE, and outlines oral antimicrobial regimens which may be most appropriate for use in the treatment of IE. For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter! You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
EMplify September 2020 – Infective Endocarditis Topics: Definition and new classification methods. Changes in at-risk patients in the U.S. History and Examination Imaging Chest Xray Trans-throacic Echocardiography (TTE) Trans-esophagel Echocardiography (TEE) CT Angiography MRI Bacteriology Antibiotics Summary Write us at emplify@ebmedicine.net
This week's episode is all about infective endocarditis. We discuss the approach to a patient presenting with suspected endocarditis, review work up, antibiotic therapy and surgical indications, and highlight the updated AHA/ACC prophylaxis guidelines! Podcast written by: Dr. Liam Finlay (Internal Medicine Resident)Reviewed by: Dr. Zain Chagla (Infectious Disease Specialist) and Dr. Leslie Martin (General Internist) Infographic by: Howard Ong (Medical Student)
Andre Maddison, General Internal Medicine (GIM) fellow at Western University, is hosting this week's episode on The Rounds Table alongside Mike Nicholson, clinical fellow in cystic fibrosis at the University of Toronto. Together they are covering antibiotic prophylaxis and incidence of infective endocarditis and baloxavir marboxil for uncomplicated influenza. Influenza viruses are emerging resistance to ... The post Quit Buggin' Me: Antibiotic Prophylaxis for Infective Endocarditis and Baloxavir Marboxil for Uncomplicated Influenza appeared first on Healthy Debate.
Andre Maddison, General Internal Medicine (GIM) fellow at Western University, is hosting this week's episode on The Rounds Table alongside Mike Nicholson, clinical fellow in cystic fibrosis at the University of Toronto. Together they are covering antibiotic prophylaxis and incidence of infective endocarditis and baloxavir marboxil for uncomplicated influenza. Influenza viruses are emerging resistance to ...The post Quit Buggin' Me: Antibiotic Prophylaxis for Infective Endocarditis and Baloxavir Marboxil for Uncomplicated Influenza appeared first on Healthy Debate.
Andre Maddison, General Internal Medicine (GIM) fellow at Western University, is hosting this week's episode on The Rounds Table alongside Erin Spicer, faculty member in GIM also at Western University. This week they cover partial oral versus intravenous antibiotic treatment of infective endocarditis (POIATE trial) and microvascular outcomes in patients with type 2 diabetes mellitus ... The post POIATEic Insight: Oral versus Intravenous Treatment for Infective Endocarditis & Bariatric Surgery in Diabetes appeared first on Healthy Debate.
Andre Maddison, General Internal Medicine (GIM) fellow at Western University, is hosting this week's episode on The Rounds Table alongside Erin Spicer, faculty member in GIM also at Western University. This week they cover partial oral versus intravenous antibiotic treatment of infective endocarditis (POIATE trial) and microvascular outcomes in patients with type 2 diabetes mellitus ...The post POIATEic Insight: Oral versus Intravenous Treatment for Infective Endocarditis & Bariatric Surgery in Diabetes appeared first on Healthy Debate.