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Dr. Dan Ackerman and Dr. Reza Bavarsad Shahripour discuss the diagnostic performance of 4 major modalities: TCD, TTE, TEE, and cardiac CT in patients with embolic stroke of undetermined source. Sho citation: Read the related article in Neurology® Clinical Practice.
Dr. Dan Ackerman talks with Dr. Reza Bavarsad Shahripour about the diagnostic performance of 4 major modalities: TCD, TTE, TEE, and cardiac CT in patients with embolic stroke of undetermined source. Read the related article in Neurology® Clinical Practice. Disclosures can be found at Neurology.org.
Rodman live from Trance In the Woods, Not So Secret Stage, 30.05.26. Choose your player
durée : 00:06:18 - Grand Reportage - par : Aurélie Kieffer - À 28 ans, Zelliana est titulaire d'un master en neurobiologie. Mais parfois, elle parle comme une enfant de 8 ans et dit se prénommer Irish. Son cerveau abrite ainsi plus de dix personnalités. Psychiatre, Pr Hingray rappelle que le trouble dissociatif de l'identité reste, à tort, très controversé. - réalisation : Tara Schlegel, Annie Brault, Caroline Bennetot, Éric Chaverou Vous aimez ce podcast ? Pour écouter tous les épisodes sans limite, rendez-vous sur Radio France
durée : 00:02:14 Vous aimez ce podcast ? Pour écouter tous les épisodes sans limite, rendez-vous sur Radio France
They're Listening, Drupal, TTE, KEV, Mythos, Megalodon, Boris and Natasha, MFA, Pope Leo, Aaran Leyland, and More on the Security Weekly News. Visit https://www.securityweekly.com/swn for all the latest episodes! Show Notes: https://securityweekly.com/swn-584
They're Listening, Drupal, TTE, KEV, Mythos, Megalodon, Boris and Natasha, MFA, Pope Leo, Aaran Leyland, and More on the Security Weekly News. Show Notes: https://securityweekly.com/swn-584
They're Listening, Drupal, TTE, KEV, Mythos, Megalodon, Boris and Natasha, MFA, Pope Leo, Aaran Leyland, and More on the Security Weekly News. Visit https://www.securityweekly.com/swn for all the latest episodes! Show Notes: https://securityweekly.com/swn-584
They're Listening, Drupal, TTE, KEV, Mythos, Megalodon, Boris and Natasha, MFA, Pope Leo, Aaran Leyland, and More on the Security Weekly News. Show Notes: https://securityweekly.com/swn-584
durée : 00:21:24 - A trois jours de la finale de Ligue des champions entre le PSG et Arsenal, on répond à une question proprement existentielle : le football pratiqué par les Gunners est-il vraiment si moche ? - réalisation : Pia Clemens Vous aimez ce podcast ? Pour écouter tous les épisodes sans limite, rendez-vous sur Radio France
durée : 00:58:25 - Le Book Club - par : Marie Richeux - Camille vit dans les Ardennes, il dialogue avec son double intérieur et arpente une région chargée d'histoire. L'enfant promène son regard poétique sur le monde qui l'entoure dans un roman aux allures de conte à la fois sombre et lumineux. - réalisation : Vivien Demeyère - invités : Gérard Lefort Journaliste, critique de cinéma et écrivain
We welcome our Artist of the Year 2025 - Transaphonic to The Trance Empire guestmix. Choose your player
durée : 00:06:30 - L'invité de 8h15 de "ici Gascogne" - Chaque jour pendant les vacances de Pâques, un gendarme landais raconte l'affaire, l'intervention qui a marqué sa carrière. Ce jeudi matin, la colonelle Fifonsi-Gwladys Quenum Possy-Berry, commandante en second du groupement, revient sur un "cas d'école" en matière de police scientifique. Vous aimez ce podcast ? Pour écouter tous les autres épisodes sans limite, rendez-vous sur Radio France.
durée : 00:27:59 - Les Pieds sur terre - par : Sonia Kronlund - Allongé dans l'herbe, au milieu de la ville, ou au bord de la mer, le nez en l'air pointé vers le ciel, qui n'a pas un jour regardé défiler les nuages ? A quoi font penser ces cheveux d'ange, ces gros nuages lourds, ou ces petits floconneux ? De 5 à 88 ans, les réponses fusent sous le ciel… - réalisation : Sandrine Chapron, Élise Andrieu, Charlotte Bienaimé, Amaury Chardeau, Leila Djitli, Rémi Dybowski Douat, Morgane Du Liège, Bahar Makooi, Pauline Maucort, Olivier Minot, Nicolas Ruffault, Delphine Saltel, Jérôme Sandlarz, Farida Taher, Léa Veinstein, Julie Beressi, Alexandra Malka, Annabelle Brouard, Emmanuel Geoffroy Vous aimez ce podcast ? Pour écouter tous les épisodes sans limite, rendez-vous sur Radio France
It's 20 years since the 106 season and 15 years since Wimb started The Tilehurst End! Ben and Ross bring on the founder for a breakdown of the Wigan Athletic game and a walk down TTE memory lane. With the 106 season celebration coming up, Ross quizzes his (said with love) older compatriots on their memories from the campaign, and the lineup from the promotion-winning game in Leicester City. Thanks as always to our friends at ZCZ Films for sponsoring the pod Thank you to The Amazons for providing the theme song Thank you to Siren Brewing - Get 10% off your next Siren order. Use code TILEHURST10 at the checkout on a minimum spend of £30. Follow The Tilehurst End on Twitter @thetilehurstend Follow Ross on Bluesky @webberross.bsky.social Follow Ben on Twitter @mrblthomas
durée : 00:12:35 - Les Enjeux internationaux - par : Guillaume Erner - Au Danemark, Mette Frederiksen s'affirme à l'international face aux crises, mais sa popularité étrangère suffit-elle à séduire les électeurs danois, divisés et attentifs aux clivages nationaux et aux coalitions ? - réalisation : Félicie Faugère - invités : Christelle Meilland Chercheuse à l'Institut de recherches économiques et sociales (IRES)
durée : 00:03:58 - Le Grand reportage de France Inter - David Guiraud est arrivé largement en tête du premier tour des élections municipales à Roubaix, dimanche 15 mars, avec 46,64% des voix, loin devant son adversaire de la droite, Alexandre Garcin, et ses 20,09%. Il repart désormais en campagne pour essayer de consolider son avance. - réalisation : Matthieu Bonhoure Vous aimez ce podcast ? Pour écouter tous les épisodes sans limite, rendez-vous sur Radio France
La previsión pivotaba en torno a la posibilidad de disfrutar de unprograma de radio con un plus de extraordinario. Los motivosno estaban claros, pero las coordenadas estelares así lodejaban entrever. Una vez finalizado, la conclusión es que nonos hemos equivocado. Interesante sí, no para tirar cohetes,pero sí muy completo, lleno de conversaciones distintas eimpactantes. Lo demuestra el hecho de que, a pesar de habersido cinco y no seis los invitados, nos ha seguido faltandotiempo para poder exponer todo el trabajo previamenterealizado.Aún así, tiempo hemos tenido en la presentación para explicarnuestra opinión en torno a la cínica y camaleónica posición delgobierno para con el conflicto en irán, así como para hablar,cuando ya estábamos en los estertores del programa, de eseabrazo sincero entre el Rey Felipe VI y la Nobel María CorinaMachado. Un tema que también nos ha servido para conectarcon nuestro colaborador Francisco González, que estos días seencuentra en Venezuela, y nos ha explicado como se ve este yotros temas desde esa joya sudamericana venida a menos porculpa de los últimos 30 años de dictadura chavista.Entre medias, otros tantos invitados de un programa que se hainaugurado con la presencia de Ana Pellicer, 1ª Tte. De alcaldedel ayuntamiento de Benidorm, con la que hemos repasado,aunque por encima, sus casi 11 años de concejal y alcaldesaen funciones que tantas veces ha ejercido. A ella le ha cogidoel relevo en el micrófono otro edil, en este caso de obras ymovilidad, y es que Francis Muñoz es hoy día el protagonistade la vida pública en la ciudad de Benidorm, con la puesta enmarcha de las obras de la avenida Jaime I que derivarán en unportentoso parking dentro de 15 meses.Y entre el principio y el final, dos temas curiosos y atractivos.Han vuelto hasta LEO RADIO nuestro grandes peregrinos:Fernando escudero y Álvaro Lazaga. Con ellos hemosdisfrutado durante un largo rato del Camino de Santiago.Pasado, presente y futuro se han fundido en una apasionadaconversación que yo no dejaría de escuchar. Para finalizardespués con la escritora, speaker y mentora Rose Polo, quedesde su experiencia, ha venido a presentarnos el nuevocírculo para mujeres que tiene previsto realizar el próximo 5 deabril de 10 a 14 h en Muchamiel. Vale la pena conocerla y, encaso de estar en período de búsqueda personal, acudir a suencuentro.
durée : 01:48:21 - Soft Power - par : Frédéric Martel - Fondée en 2012, la Banque Publique d'Investissement (BPI) est devenue l'un des rouages clé de l'innovation française. Quatorze ans après ses débuts, le travail de l'organisme est autant salué par les uns que ciblé par les autres. Soft Power reçoit son directeur, Nicolas Dufourcq. - réalisation : Peire Legras, Alexandra Malka - invités : Nicolas Dufourcq Directeur général de Bpifrance; Pierre-Olivier Costa Président du Mucem.; Charlotte Casiraghi Ecrivaine, présidente et co-fondatrice des Rencontres Philosophiques de Monaco
Two hours of the best Trance music, this is episode 412 of The Trance Empire, with your host, Rodman. Choose your player
Two hours of the best Trance music, this is episode 411 of The Trance Empire, with your host, Rodman. Choose your player
- INTRO (00:00:00) - PRESENTACIÓN (00:02:37): ¡¡con Javo del podcast "La hora de los marcianitos"!! - OJETE AVIZOR (00:09:53): Lanzamientos / Más casting de la serie de GoW / Los del Expedition se hacen caballeros / Serie de Baldur's Gate - NOTICIAS DE MIERDA (00:27:10): CAPCOM liberará el virus-T / Te jodes con tu Labo VR de cartón / Fracaso de 2XKO y despidos / Muria, el betatester de PC Fútbol 8 da la cara (y bebe en taza) / Más cancelaciones de Ubisoft - *DE-VATER - REIVINDICANDO EL FRIKISMO (00:42:50)*: Debatimos sobre cómo los frikis hemos pasado de ser los estigmatizados por la sociedad a, de una manera u otra, mover el mundo (porque sí, con nuestra cartera lo movemos bastante…). ¿Qué pasó por el camino? También nos sinceramos sobre nuestro pasado y os contamos cuán frikis somos. - ENDING (02:13:18) SUSCRIBETE (y TIRANOS LA SUSCRIPCIÓN PRIME A LA CARA) Anímate y déjanos en comentarios tu amorcito ❤️ O pásate por nuestro grupo de Telegram: https://t.me/ILTjuegos ⏬ Aquí puedes pasar el rato con nosotros ⏬ - Twitch: https://twitch.tv/ILTjuegos - YouTube: https://www.youtube.com/@iltjuegos - iVoox: https://www.ivoox.com/podcast-iltjuegos_sq_f1446764_1.html - Spotify: http://spotify.iltjuegos.com - Apple Podcasts: http://itunes.iltjuegos.com - Instagram: https://www.instagram.com/iltjuegos - X (Twitter): https://x.com/iltjuegos - TikTok: https://www.tiktok.com/@iltjuegos Agradecimientos - Gracias a tod@s por vernos o escucharnos cada semana. - Gracias a Jose Manuel Fernández 'Spidey' por el tema chiptune del outro y a todo Metodologic por estar siempre ahí. - Gracias a Suno por brindarnos una IA para hacer el tema de la intro "Los chachos se han pasado al Twitch". - Gracias a https://ocremix.org y a todos los artistas que aparecen en el streaming con sus creaciones como cama musical y que hacen este programa mejor. Si estás escuchando la versión podcast de este streaming, recordarte que puedes consultar los artistas de todos los temas a través de la versión streaming (Twitch o YouTube) de este episodio de ILT Juegos.
Two hours of the best Trance music, this is episode 407 of The Trance Empire, with your host, Rodman. Choose your player
We open the mailbag to answer your questions on whether Life Insurance Retirement Plans (LIRPs) are a scam, if spending millions on a Super Bowl commercial is ever a good idea (looking at you, CrowdStrike), and if equal-weight S&P 500 ETFs are the best way to hedge against a tech crash. Plus, we debate the future of the energy sector, discuss the power of "stock cannibals" like Adobe and PayPal, and reveal the two stocks we think could generate life-changing returns over the next 15 years.01:44 Housekeeping and Listener Support02:53 Diving into Listener Questions03:04 Explaining Life Insurance Retirement Plans09:03 Super Bowl Commercials: Worth the Investment?16:47 Exploring ETF Diversification23:10 Introduction and Wayne's Email23:17 Colin's Energy Market Inquiry24:04 Oil and Gas Market Dynamics27:38 Investment Strategies in Energy Sector29:48 Wayne's Question on ADRs32:17 John's Query on Stock Buybacks37:41 Ramey's AI and Investment Question43:27 Future Investment Picks47:23 Spam Comment of the MonthCompanies mentioned: ADBE, AZO, CRWD, GDDY, KNSL, KR, ORLY, PSX, PYPL, RKLB, TBBB, TTE, TXNFind where to listen & subscribe, portfolio contests, and contact information at https://investingunscripted.com*****************************************To get 15% off any paid plan at fiscal.ai, visit https://fiscal.ai/unscriptedListen to the Chit Chat Stocks Podcast for discussions on stocks, financial markets, super investors, and more. Follow the show on Spotify, Apple Podcasts, or YouTube*****************************************Join our PatreonSubscribe to our portfolio on Savvy Trader
Two hours of the best in Trance music, this is a 138 & 140 bpm special episode 406 of The Trance Empire, with your host, Rodman. Choose your player
Two hours of the best in Trance music, this is episode 405 of The Trance Empire, with your host, Rodman. Choose your player
durée : 00:05:16 - La Revue de presse internationale - par : Catherine Duthu - Dans un Iran privé d'Internet, impossible de connaître le bilan précis de la répression menée par le régime contre les manifestations qui durent depuis deux semaines mais des médias parlent de 3 000 voire 12 000 morts. Portraits de victimes de cette répression, tuées par balles ou bientôt exécutées.
Two hours of the best in Trance music, this is episode 404 of The Trance Empire, with your host, Rodman. Choose your player
Two hours of the best in Trance music, this is episode 403 of The Trance Empire, with your host, Rodman. Choose your player
Oh dear: the Leam Richardson bump comes crashing down as Reading lose two games with a whimper in the space of four days. TTE writer Bobbins joins Ross to discuss the fallout from the two games and helps dissect a mailbag full of frustrated Royals. Plus, the pair discuss Lewis Wing's recent impact on the team, the seeming lack of leaders and the silent style of Joel Pereira, and the recruitment mistakes that need correcting in the next transfer windows. Thanks as always to our friends at ZCZ Films for sponsoring the pod! Thank you to The Amazons for providing the theme song! Follow The Tilehurst End on Twitter @thetilehurstend Follow Ross on Bluesky @webberross.bsky.social Follow Bobbins on Twitter @ohbobbins
durée : 00:00:57 - Idée derrière la tête Vous aimez ce podcast ? Pour écouter tous les autres épisodes sans limite, rendez-vous sur Radio France.
durée : 00:17:27 - Le monde d'Elodie - par : Elodie SUIGO - Tous les jours, une personnalité s'invite dans le monde d'Élodie Suigo. Mardi 16 décembre 2025, le vététiste de l'extrême Kilian Bron. Il publie son autobiographie, "Le vélo m'a sauvé", aux éditions Flammarion. Vous aimez ce podcast ? Pour écouter tous les autres épisodes sans limite, rendez-vous sur Radio France.
Celebrating 400 episodes of The Trance Empire, this is a live recording of Rodman solo and Rodman b2b with Jasmine Lorna from TTE 400 Live in Sheffield taken on Saturday, December 6th @ Plot 22. PART 1 - RODMAN SOLO Rene Ablaze - Tokyo [FSOE] Lange feat. Skye - Drifting Away (U-Mount Bootleg) [White Label] C-Systems, Aina - In The Cold [In Trance We Trust] K.O.V.I. Project - Searching [Alter Ego] Robin McIlmoyle, G. Summers & Ren Faye - Paradise Here [Think Trance] Transaphonic & Ren Faye - Nothing On Your Love [ZYX Trance] Dogzilla - Without You (Rodman's Blinding Lights Remix) [White Label] Rodman - Storm [SPACE 4] Rodman - Aurora [Ascent] Para X - Elarion [ZYX Trance] Paul Miller, Sneijder - En Route [Who's Afraid Of 138?!] Chris Hunt - Unifier [We Love Trance] RAM & Arctic Moon & Stine Grove - A Billion Stars Above (Darren Porter Remix) [Nocturnal Knights] C-Quence, Fictivision, Ferry Tayle & Tonks - Symbols (Mirage Remix) [In Trance We Trust] Drival, Christina Novelli - Save My Life (Steve Allen Remix) [AVA White] Phil Stringer feat. Carolann Curran - My Love [Reason II Rise Uplift] Ferry Corsten, Gouryella & Saskia Lie Atjam - Marama (Moon & Stars) [Flashover] ***** PART 2 - RODMAN b2b JASMINE LORNA Ralphie B, Frank Waanders & Collide1 - No Tomorrow [Find Your Harmony] Billy Gillies - Expand [Afterdark] John O'Callaghan - Riverside (Paul Denton Remix) [Subculture] Ferry Corsten, Ben Hemsley & Rose Gray - Tidal [Armada Music] Matt Robertson - Sunstruck [VANDIT] CRW - I Feel Love (Omar Sherif Remix) [Grotesque] Rodman - Runway [State Control] Trance Wax - Ascend (Sneijder Remix) [Armada Music] Asteroid - Kanjō [FSOE] Enigma State - State Of Mind (Bryan Kearney Rework) [Kearnage] David Forbes, Susie Ledge - Lose Ma Head [Who's Afraid Of 138?!] The Rocketman - Strange World [Armada Music] Giuseppe Ottaviani - Linking People [VANDIT] Everything TTE
TTE editor Simeon Pickup is on the pod to discuss Reading's first league win in Blackpool for two decades. Ross runs through the things that can still improve after an impressive 3-0 win, and Ben comes around on Daniel Kyerewaa, lauding his breakout performance in Royal colours. The TTE team also discuss Kelvin Ehibhatiomhan's evolving role at the club and how it may look after Jack Marriott returns to fitness. Thanks as always to our friends at ZCZ Films for sponsoring the pod! Thank you to The Amazons for providing the theme song! Follow The Tilehurst End on Twitter @thetilehurstend Follow Ross on Bluesky @webberross.bsky.social Follow Ben on Twitter @mrblthomas Follow Sim on Twitter @simfrombucks
durée : 00:11:39 - L'invité de 7h50 du week-end - par : Ali Baddou, Marion L'hour - Audrey Azoulay vient de terminer son deuxième mandat à la tête de l'Unesco. La désormais ex-directrice générale de l'institution internationale est l'invitée de 7h50. Vous aimez ce podcast ? Pour écouter tous les autres épisodes sans limite, rendez-vous sur Radio France.
In this week's episode of Dividend Talk, we're back with a jam-packed Dividend Announcements & Earnings deep dive.We kick things off with PayPal initiating its first-ever dividend (welcome to the club, Monkey!), Hershey holding flat to stay off the aristocrat chopping block, and a wild stat on revenue-per-employee (OnlyFans crushes tech giants at $37.6M per head). Then it's over to dividend hikes from Iberdrola (+8.2%), Rockwell Automation, AbbVie, and ExxonMobil, before diving into earnings: Nestlé's volume rebound in China, Schneider Electric riding data-center tailwinds, Altria's cash-rich but growth-poor reality, UnitedHealth's margin squeeze, T. Rowe Price outflows, and Shell's $10B FCF buyback machine.In the Q&A, we tackle benchmarking vs. S&P 500, dollar-cost-averaging into falling knives, estate tax broker moves, covered-call ETFs, Finnish gems, Evolution's permanent pivot, and stock-specific takes on Novo Nordisk, APD, Qualcomm, and more.SEE YOU ON THE INSIDE!!Tickers discussed: PYPL, HSY, GOOGL, MSFT, EBAY, AMZN, IBM, MCD, IEP, IBDR.MC, MUM.DE, SIE.DE, APD, LIN, NOVO-B.CO, EVO.ST, QCOM, ARE, ADC, MO, BATS.L, PM, UNH, TROW, SHEL, XOM, TTE, ITW, ABT, ADP, SCHN.PA, ROC.AX, NOVN.SW, NESN.SW, MCD, APH, DHR, TXN, VFC, RELAS, VWS.CO, WSO, GRG.LJoin us:[Facebook] – Https://www.facebook.com/groups/dividendtalk[Twitter] – @DividendTalk_ , @European_DG[Discord] – https://discord.gg/nJyt9KWAB5[Premium Services] – https://dividendtalk.eu/download-your-free-samples/[Malmo Meetup] – https://t.co/STgV1nMWKj
In this week's episode of Dividend Talk, we're back with Q3 Earnings Roundup.We kick things off with Novo Nordisk shaking up half its board of directors, before covering two big dividend announcements from McDonald's and Amphenol. Then it's over to earnings, where we break down results from Germany's Mensch und Maschine, Danaher, Evolution Gaming, and Texas Instruments.We also review a listener portfolio from “Bella Dividends,” packed with high-yield European names, and share our thoughts on diversification, growth balance, and dividend safety.In the Q&A, we talk estate tax and brokers, the future of quarterly reports, DCF vs. dividend discount models, and stock-specific questions on Intel, TotalEnergies, Watsco, and GreenCoat UK.SEE YOU ON THE INSIDE!!Tickers discussed: NVO, MCD, APH, MUM.DE, DHR, EVO.ST, TXN, SHEL, IBM, TTE, INTL, WSO, RELAS, IBDR.MC, VWS.COJoin us:[Facebook] – Https://www.facebook.com/groups/dividendtalk[Twitter] – @DividendTalk_ , @European_DG[Discord] – https://discord.gg/nJyt9KWAB5[Premium Services] – https://dividendtalk.eu/download-your-free-samples/[Malmo Meetup] – https://t.co/STgV1nMWKj
durée : 00:45:24 - La 20e heure - par : Eva Bester - Le réalisateur israélien, auréolé de nombreux prix, vient nous présenter son dernier film « Oui », ou l'histoire d'un musicien précaire à qui l'on confie une tâche de la plus haute importance : la mise en musique d'un nouvel hymne national à la gloire de l'action militaire israélienne à Gaza. Vous aimez ce podcast ? Pour écouter tous les autres épisodes sans limite, rendez-vous sur Radio France.
durée : 00:02:43 - Regarde le monde - Direction la Corée du Nord. Alors que Donald Trump envisage une nouvelle rencontre avec Kim Jong-un, rencontre ce matin avec la fille du dictateur. Vous aimez ce podcast ? Pour écouter tous les autres épisodes sans limite, rendez-vous sur Radio France.
durée : 00:02:43 - Regarde le monde - Direction la Corée du Nord. Alors que Donald Trump envisage une nouvelle rencontre avec Kim Jong-un, rencontre ce matin avec la fille du dictateur. Vous aimez ce podcast ? Pour écouter tous les autres épisodes sans limite, rendez-vous sur Radio France.
durée : 00:04:13 - Comme personne - Sur l'île de São Miguel, Madalena Motta dirige l'une des deux seules plantations de thé d'Europe, et la plus ancienne. Héritière d'un savoir-faire familial, elle mêle tradition, innovation et engagement social dans son exploitation centenaire.
durée : 00:47:41 - Affaires sensibles - par : Fabrice Drouelle, Franck COGNARD - Aujourd'hui dans Affaires Sensibles, Zidane, histoire d'un coup de tête - réalisé par : Frédéric Milano Vous aimez ce podcast ? Pour écouter tous les autres épisodes sans limite, rendez-vous sur Radio France.
CardioNerds (Drs. Rick Ferraro and Georgia Vasilakis Tsatiris) discuss ATTR cardiac amyloidosis with expert Dr. Justin Grodin. This episode is a must-listen for all who want to know how to diagnose and treat ATTR with current available therapies, as well as management of concomitant diseases through a multidisciplinary approach. We take a deep dive into the importance of genetic testing, not only for patients and families, but also for gene-specific therapies on the horizon. Dr. Grodin draws us a roadmap, guiding us through new experimental therapies that may reverse the amyloidosis disease process once and for all. Audio editing by CardioNerds academy intern, Christiana Dangas. This episode was developed in collaboration with the American Society of Preventive Cardiology and supported by an educational grant from BridgeBio. Enjoy this Circulation Paths to Discovery article to learn more about the CardioNerds mission and journey. US Cardiology Review is now the official journal of CardioNerds! Submit your manuscripts here. CardioNerds Cardiac Amyloid PageCardioNerds Episode Page Pearls: You must THINK about your patient having amyloid to recognize the pattern and make the diagnosis. Start with a routine ECG and TTE, and look for a disproportionately large heart muscle with relatively low voltages on the ECG. Before you diagnose ATTR amyloidosis, AL amyloidosis must be ruled out (or ruled in) with serum light chains, serum/urine immunofixation, and/or tissue biopsy. Genetic testing is standard of care for all patients and families with ATTR amyloidosis, and the future is promising for gene-specific treatments. Current FDA-approved treatments for TTR amyloidosis are TTR stabilizers and TTR silencers, but TTR fibril-depleting agents are on their way. Early diagnosis of ATTR affords patients maximal benefit from current amyloidosis therapies. TTR amyloidosis patients require a multidisciplinary approach for success, given the high number of concomitant diseases with cardiomyopathy. Notes: Notes: Notes drafted by Dr. Georgia Vasilakis Tsatiris. What makes you most suspicious of a diagnosis of cardiac amyloidosis from the typical heart failure patient? You must have a strong index of suspicion, meaning you THINK that the patient could have cardiac amyloidosis, to consider it diagnostically. Some characteristics or “red flags” to not miss: Disproportionately thick heart muscle with a relatively low voltages on EKG Bilateral carpal tunnel syndrome – estimated that 1 in 10 people >65 years old will have amyloidosis Previously tolerated antihypertensive medications Atraumatic biceps tendon rupture Bilateral carpal tunnel syndrome Spinal stenosis Concomitant with other diseases: HFpEF, low-flow low-gradient aortic stenosis How would you work up a patient for cardiac amyloidosis? Start with a routine ECG (looking for disproportionally low voltage) and routine TTE (looking for thick heart muscle) CBC, serum chemistries, hepatic function panel, NT proBNP, and troponin levels NOTE: It is critical to differentiate between amyloid light chain (AL amyloidosis) and transthyretin ATTR amyloidosis, as both make up 95-99% of amyloidosis cases. Obtain serum free light chains, serum & urine electrophoresis, and serum & urine immunofixation to rule out AL amyloidosis. (See table below) AL Amyloidosis ATTR Amyloidosis → Positive serum free light chains and immunofixation (Abnormal M protein) → Tissue biopsy (endomyocardial, fat pad) to confirm diagnosis → Negative serum free light chains and immunofixation (ruled out AL amyloidosis) → Cardiac scintigraphy (Technetium pyrophosphate with SPECT imaging) What treatment options do we have to offer now for ATTR CM, and how has this compared to prior years? Before 2019, treatment options were limited outside of cardiac tr...
CardioNerds (Dr. Rick Ferraro and Dr. Dan Ambinder) join Dr. Sahar Samimi and Dr. Lorraine Mascarenhas from Baylor College of Medicine, Houston, Texas, at the Houston Rodeo for some tasty Texas BBQ and a tour of the lively rodeo grounds to discuss an interesting case full of clinical pearls involving a patient with nonbacterial thrombotic endocarditis (NBTE). Expert commentary is provided by Dr. Basant Arya. Episode audio was edited by CardioNerds Intern Dr. Bhavya Shah. (Photo by Xu Jianmei/Xinhua via Getty Images)Xinhua News Agency via Getty Images We discuss a case of a 38-year-old woman with advanced endometrial cancer who presents with acute abdominal pain, found to have splenic and renal infarcts, severe aortic regurgitation, and persistently negative blood cultures, ultimately diagnosed with nonbacterial thrombotic endocarditis (NBTE). We review the definition and pathophysiology of NBTE in the context of malignancy and hypercoagulability, discuss initial evaluation and echocardiographic findings, and highlight important management considerations. Emphasis is placed on the complexities of anticoagulation choice, the role of valvular surveillance, and the need for coordinated, multidisciplinary care. US Cardiology Review is now the official journal of CardioNerds! Submit your manuscript here. CardioNerds Case Reports PageCardioNerds Episode PageCardioNerds AcademyCardionerds Healy Honor Roll CardioNerds Journal ClubSubscribe to The Heartbeat Newsletter!Check out CardioNerds SWAG!Become a CardioNerds Patron! Pearls- Nonbacterial Thrombotic Endocarditis Eliminate the Usual Suspects. NBTE is a diagnosis of exclusion! Always rule out infective endocarditis (IE) first with serial blood cultures and serologic tests. More than Meets the Echo. Distinguishing NBTE from culture-negative endocarditis can be tricky. Look beyond the echo—focus on clinical context (underlying malignancy, autoimmune issues) and lab findings to clinch the diagnosis. TEE for the Win... Mostly. While TEE is more sensitive than TTE, NBTE vegetations can be sneaky and may embolize quickly. Don't hesitate to use advanced imaging (i.e., cardiac MRI, CTA) or repeat imaging if you still suspect NBTE. Choose your champion. In cancer-associated NBTE, guideline recommendations for anticoagulation choice are lacking. Consider DOACs and LMWH as agents of choice, but ultimately use shared decision-making to guide management. No obvious trigger? Go hunting for hidden malignancies or autoimmune disorders. A thorough workup is essential to uncover the driving force behind NBTE. Check out this state-of-the-art review for a comprehensive, one-stop summary of NBTE: European Heart Journal, 46(3), 236–245. Please note that the figures and tables referenced in the following notes are adapted from this review. notes- Nonbacterial Thrombotic Endocarditis Notes were drafted by Dr. Sahar Samimi. What is nonbacterial thrombotic endocarditis (NBTE)? NBTE, previously known as marantic endocarditis, is a rare condition in which sterile vegetations form on heart valves.1 It occurs most commonly in association with malignancies and autoimmune conditions (i.e, antiphospholipid antibody syndrome or systemic lupus erythematosus).1 In addition, NBTE has been reported in association with COVID-19 infection, burns, sepsis, and indwelling catheters.2 Precise mechanisms remain unclear, but an interplay of endothelial injury, hypercoagulability, hypoxia, and immune complex deposition contributes to the formation of these sterile vegetations. 1 How do we diagnose NBTE? Physicians should have a high level of suspicion for NBTE in at-risk patients (e.g., with active malignancy) who present with recent or recurrent embolic events (i.e., stroke, splenic, renal, or mesenteric infarct, and acute coronary syndrome).1
En este episodio cubrimos los eventos más relevantes antes de la apertura del mercado: • Wall Street cede terreno ante tensiones geopolíticas: Futuros a la baja: $SPX -0.3%, $US100 -0.3%, $INDU -0.2%. El posible ataque de EE.UU. a Irán en las próximas semanas mantiene la incertidumbre elevada. El 10Y se mantiene en 4.39% y el 2Y en 3.95%. La Fed dejó tasas sin cambios esta semana y Powell reafirmó su enfoque prudente. Hoy se publican el índice manufacturero de la Fed de Filadelfia (-1.7 esperado) y el Leading Index de mayo (-0.1%). • Tesla lanza megaproyecto de baterías en Shanghái: $TSLA firmó un acuerdo de $556.8M con el gobierno de Shanghái y Kangfu Leasing para su primer desarrollo Megapack a escala de red en China. La instalación fortalecerá su presencia en almacenamiento energético global. La acción sube +1.3% premarket. • La IEA exige mejoras ambientales al sector GNL: Según un nuevo informe, las emisiones del GNL podrían reducirse hasta 60% con electrificación, captura de metano y tecnologías CCUS. El GNL emite 25% menos que el carbón, pero sigue representando 350 Mt CO₂eq al año. La IEA urge acción de actores como $SHEL, $XOM, $TTE y $CVX. • Circle sube tras aprobación del GENIUS Act: $CRCL avanza +12% y acumula +34% desde el miércoles. El Senado aprobó la ley que regula los stablecoins respaldados en dólares y Treasuries, con auditorías y protecciones al consumidor. El proyecto pasa ahora a la Cámara. El senador Hagerty destacó su impacto para fortalecer el dólar y controlar la innovación cripto desde EE.UU. Una jornada con foco en geopolítica, energía limpia y el avance del marco legal para activos digitales. ¡No te lo pierdas!
En este episodio cubrimos los eventos más importantes antes de la apertura del mercado: • Wall Street se estabiliza tras tensión Irán–Israel: Futuros al alza: $SPX +0.5%, $US100 +0.6%, $INDU +0.4%. A pesar de nuevos bombardeos israelíes el domingo, el mercado reacciona sin pánico. Rendimientos al alza: bono a 10 años $US10Y en 4.45%, 2 años $US2Y en 3.99%. Esta semana, el foco es la Fed. Se espera que mantenga tasas sin cambios el miércoles, con Powell adoptando tono cauto ante la presión del crudo. Hoy se publica el Empire State (estimado: -5.90). • Nvidia avanza con su estrategia de IA soberana: $NVDA impulsa proyectos en Reino Unido, Francia y Alemania para desarrollar infraestructuras propias de IA. Incluye una nube industrial junto a Deutsche Telekom, y “Mistral Compute” con Mistral AI. Colabora también con fondos europeos y proveedores regionales para democratizar acceso a modelos de lenguaje y cómputo avanzado. • Amazon y Roku integran mayor red de CTV en EE.UU.: $AMZN y $ROKU lanzan integración exclusiva en Amazon DSP con alcance a 80M de hogares. Mejora targeting en Prime Video, Roku Channel, Tubi, Disney, FOX y más. Las pruebas iniciales redujeron la repetición publicitaria en un 30% y mejoraron alcance único un 40% con el mismo presupuesto. • Kratos refuerza producción nacional de motores militares: $KTOS construirá nueva planta en Oklahoma para fabricar motores turbojet GEK, comenzando con el GEK800. La instalación será de 100K pies², cinco líneas y operará a pleno en Q4 2026. Se crearán más de 100 empleos calificados y fortalece la defensa industrial según el CEO DeMarco. • TotalEnergies expande exploración en Golfo con Chevron: $TTE adquirió 25% de 40 bloques offshore operados por $CVX. Las áreas clave incluyen Walker Ridge y Mississippi Canyon. Refuerza alianza en proyectos como Anchor y Jack. Además, $TTE aumentará inversión en electricidad al 30% del capex, buscando que represente el 20% del portafolio para 2030. Una jornada de transición tras tensión geopolítica, con foco en tecnología, energía y política monetaria. ¡No te lo pierdas!
durée : 00:23:41 - L'invité de 8h20 : le grand entretien - par : Nicolas Demorand, Léa Salamé - Anthony Samradi, Gérard Araud et Isabelle Lasserre étaient les invités de Léa Salamé et Nicolas Demorand ce lundi. Ils apportent leur éclairage sur la situation entre Israël et l'Iran.
durée : 00:58:47 - Concordance des temps - par : Jean-Noël Jeanneney - Longtemps consommée dans toutes les catégories de la société, la tête de veau mérite une histoire à la fois sociale et politique. Pierre Michon présente ce plat devenu symbole d'agapes régicides et objet d'un humour vache et inquiétant. - réalisation : Vincent Abouchar
durée : 00:13:32 - Faure/ Mayer-Rossignol, qui va prendre la tête du PS ?