Proactive - Interviews for investors

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Welcome to the Proactive podcast channel – the destination for breaking news on growth companies and up to the minute market coverage. Here we plug you into what’s new and exciting in the world of business.

Proactive


    • Sep 30, 2025 LATEST EPISODE
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    Latest episodes from Proactive - Interviews for investors

    Nextech3D.ai CEO Evan Gappelberg says Eventdex deal adds $10m upside

    Play Episode Listen Later Sep 30, 2025 5:54


    Nextech3D.AI (CSE:NTAR, OTCQX:NEXCF) CEO Evan Gappelberg talked with Proactive's Stephen Gunnion after the AI-powered event management company signed a binding letter of intent (LOI) to acquire Eventdex, a registration and badge-printing software company. The acquisition brings a suite of tools, including badging, floor plan mapping, AI matchmaking, and an app with AI navigation. Gappelberg described the move as transformative, saying it allows the company to deliver a true all-in-one solution that event organisers have been seeking. He revealed that the average order value per customer could rise from $3,000 to $20,000 due to cross-selling opportunities across over 500 annual events, noting: "It's a $10 million revenue potential just from upselling existing customers." Importantly, the deal accelerates the company's blockchain ticketing rollout. Gappelberg confirmed a launch is anticipated in Q4 2025, potentially within the next six weeks. He highlighted that blockchain technology offers fraud-free, bot-resistant ticketing and smart contract integration, giving Nextech3D.ai an opportunity to tap into the $85 billion global ticketing market. Funded entirely in cash, the acquisition avoids shareholder dilution and is expected to double revenue. The company plans further M&A activity in the fragmented event tech space. “We expect to see our business going cash flow positive in 2026 and beyond,” Gappelberg added. For more interviews like this, visit Proactive's YouTube channel. Don't forget to like this video, subscribe, and enable notifications so you never miss future updates. #Nextech3DAI #Eventdex #BlockchainTicketing #EventTech #AIEvents #SmartContracts #MergersAndAcquisitions #TechInvesting #DigitalTicketing #ProactiveInvestors

    Solvonis Therapeutics CEO on transformational first half, SVN-001 trial and licensing plans

    Play Episode Listen Later Sep 30, 2025 7:01


    Solvonis Therapeutics PLC (LSE:SVNS) Anthony Tennyson talked with Proactive's Stephen Gunnion about the company's progress following its acquisition of Awakn Life Sciences and the advancement of its lead programs targeting central nervous system (CNS) disorders. Tennyson outlined how the acquisition strengthens Solvonis's pipeline, bringing late clinical-stage assets in alcohol use disorder and psychiatry, specifically a joint venture for post-traumatic stress disorder. “With the acquisition of Awakn we're able to acquire linked clinical stage programs within addiction for alcohol use disorder and then acquire the full joint venture program... in Psychiatry for post-traumatic stress disorder,” he said. The company's lead program, SVN-001, is currently in a Phase 3 trial in partnership with the University of Exeter and the UK Department of Health. Recruitment began in July 2024, with results expected in late 2027 or early 2028. Solvonis is in licensing discussions with several pharmaceutical firms for this asset. Tennyson also provided an update on SVN-002, which targets the US market by repurposing J&J's SPRAVATO for alcohol use disorder. The FDA has agreed to a regulatory path that could bypass early-stage trials, significantly reducing costs. Key 2025 milestones include: progressing licensing for SVN-001, establishing a scientific bridge for SVN-002, and declaring a lead candidate for SVN-SDN14. For more videos like this, visit Proactive's YouTube channel. Don't forget to like this video, subscribe, and hit the notification bell to stay updated. #Solvonis #AnthonyTennyson #AlcoholUseDisorder #SVN001 #SVN002 #CentralNervousSystem #BiotechNews #CNSDisorders #DrugDevelopment #PTSDTreatment #PharmaLicensing #SPRAVATO #AwaknLifeSciences #proactiveinvestors

    Light Science CEO on PFP growth and new fire safety accreditation

    Play Episode Listen Later Sep 30, 2025 3:37


    Light Science Technologies Holdings PLC (AIM:LST) CEO Simon Deacon talked with Proactive's Stephen Gunnion about the company's progress in its Passive Fire Protection (PFP) division, highlighting the growth opportunities ahead. Deacon explained the importance of recently receiving the BS 8670 accreditation from Construction Online, which he described as “very significant” for the business. He noted that Construction Online was originally a government department and has been supporting thousands of businesses across Europe for more than 20 years in compliance and supply chain management. According to Deacon, the new accreditation is designed to “streamline the supply pre-qualification process and will really help unblock the delays across the construction industry and supply chain.” Deacon said the accreditation will further validate Light Science Technologies' expertise across safety, leadership, risk management, and fire and life protection. He also discussed the company's pipeline, which has grown to around £28 million. Recent orders worth approximately £0.5 million have been secured across the UK, covering projects in schools, hotels, social housing, and more. Looking ahead, Deacon said both the PFP and AgTech divisions are expected to be the strongest revenue generators, with net profit anticipated for the group in 2026 as backlogs clear. For more interviews and updates, visit Proactive's YouTube channel. Don't forget to give this video a like, subscribe, and enable notifications for future content. #LightScienceTechnologies #PassiveFireProtection #AgTech #ConstructionIndustry #FireSafety #UKBusiness #BuildingSafety #SupplyChain #RevenueGrowth #ProactiveInvestors

    EMV Capital CEO on H1 results, Destiny Pharma opportunity and Venture Building platform

    Play Episode Listen Later Sep 30, 2025 8:52


    EMV Capital (AIM:EMVC) CEO Dr Ilian Iliev talked with Proactive's Stephen Gunnion about the company's evolving strategy, recent investments, and focus areas following its growth to over $100 million in assets under management. Iliev noted the company has expanded from 8 to over 70 portfolio companies since its merger with NetScientific five years ago. EMV Capital continues to target deep tech and life sciences sectors, underpinned by a capital-efficient investment model. He outlined how the business is managing liquidity through diverse revenue streams and selective secondary disposals. “The core of what we're doing is we're trying to get to a point where we're covering our ongoing costs from ongoing, cash resources,” Iliev explained. A key topic was EMV Capital's acquisition of Destiny Pharma's IP and clinical assets. Iliev described the deal as part of a broader strategy to address antimicrobial resistance. The company implemented a venture build program to grow the value of the asset at no cash cost, adding £0.5 million of direct value to its balance sheet. He also discussed Martlet Capital's recent 2.5x return, which he said validated EMV's dual-playbook strategy: active venture building and minority co-investments. Looking ahead, Iliev pointed to promising growth from portfolio companies including a US-based remote patient monitoring business and Scandinavian deep tech recycling initiatives. For more interviews and updates, visit Proactive's YouTube channel. Don't forget to like the video, subscribe to the channel, and enable notifications for future content. #EMVCapital #IlianIliev #DestinyPharma #VentureCapital #LifeSciences #DeepTech #InvestmentStrategy #AIMStocks #ProactiveInvestors #MartletCapital #AntimicrobialResistance #PrivateEquity #HealthcareInnovation

    Trust Stamp launches biometric age-verification platform to tackle compliance gaps and online safety

    Play Episode Listen Later Sep 30, 2025 4:33


    Trust Stamp President Andrew Gowasack joined Steve Darling from Proactive to announce the rollout of the company's proprietary biometric-binding technology, positioning it as the critical solution to systemic failures in age-verification laws that are increasingly collapsing under real-world pressures. As governments worldwide push for stronger online safety measures, existing age-verification systems have proven inadequate. According to Gowasack, most current solutions rely on weak proxies—such as verifying a device, browser, or IP address—and then pretending this equals verifying a person. These approaches create security loopholes that can be easily exploited, leaving companies exposed to both regulatory penalties and reputational harm. Trust Stamp's newly launched solution, TrustedAge™, directly addresses these flaws. Unlike traditional systems—likened by Gowasack to a “paper ticket, easily copied or passed around”—TrustedAge functions as a biometric key permanently bound to a single user. A live biometric capture confirms that the rightful owner is present for every login session, rendering the credential useless to anyone else. The urgency for a viable solution is clear. Gowasack noted that recent challenges in the UK with VPN-based circumvention are a preview of the chaos heading to the United States, where more than two dozen states are rolling out legislation mandating age verification. Companies face potential fines of up to $10,000 per violation, creating what Gowasack called a “compliance nightmare.” Trust Stamp's technology offers a ready-to-deploy answer. After a one-time verification, the credential is permanently bound to the individual. Subsequent access requires only a quick, live selfie check—without storing sensitive biometric data. This ensures that the age credential is non-transferable, immune to theft or sharing, and closes compliance loopholes that leave companies vulnerable to both legal and financial risk. With TrustedAge, Trust Stamp positions itself at the forefront of solving one of the most urgent challenges in digital safety: enforcing age verification in a way that works, scales, and protects privacy. #proactiveinvestors #truststamp #nasdaq #idai #IdentityTech #DigitalIdentity #Fintech #GhanaID #SouthKoreaStartup #AsiaExpansion #KStartupChallenge #FinancialServices #Biometrics #TechExpansion #ProactiveInvestors #AndrewGowasack

    Medicus Pharma gets positive FDA feedback on Skinject microneedle therapy for basal cell carcinoma

    Play Episode Listen Later Sep 30, 2025 5:19


    Medicus Pharma CEO Dr Raza Bokhari joined Steve Darling from Proactive to announce that the company has received encouraging feedback from its recent Type C meeting with the U.S. Food and Drug Administration (FDA) regarding the clinical development pathway of its innovative microneedle-based therapy, Skinject™ (D-MNA), for the treatment of basal cell carcinoma (BCC). The Type C meeting focused on reviewing key elements of the protocol, including study design, endpoints, and patient population definitions for upcoming clinical trials. According to Dr. Bokhari, the FDA provided clarity and alignment on several critical points. Specifically, the agency indicated that a relative bioavailability study with D-MNA, administered under certain conditions, could serve as a basis for establishing a regulatory bridge while addressing bioavailability requirements for the product. Importantly, the FDA offered constructive and supportive guidance on multiple aspects of the proposed development program, including the appropriate primary endpoint for the next clinical study. The company must define the patient population, such as tumor size limits, lesion location restrictions, and histological confirmation requirements and design a randomized, double-blind, placebo-controlled trial to demonstrate efficacy in treating BCC. This regulatory clarity is expected to further strengthen Medicus Pharma's ongoing clinical program. The company is currently conducting its Phase 2 trial across nine clinical sites in the United States. Patient randomization began in August 2024. In March 2025, Medicus Pharma announced results from an interim analysis of the Phase 2 study, showing a positively trending clinical clearance rate exceeding 60%. The interim data, based on more than half of the targeted 60 patients randomized at the time, were highly encouraging, although final results may vary once the study is fully completed. #proactiveinvestors #nasdaq #mdcx #tsxv #mdcx #pharma #Biotech #CancerTreatment #ClinicalTrials #FDAApproval #SkinCancer #HealthcareInnovation #Investing #MedicalResearch #SkinCancer #BasalCellCarcinoma #BiotechNews #CancerResearch #UAEHealth #NonInvasiveTherapy #Doxorubicin #ClinicalTrials #HealthcareInnovation

    EnWave signs commercial license with Brazil's Solve Solutions for exclusive use of REV tech

    Play Episode Listen Later Sep 30, 2025 3:49


    EnWave Corporation CEO Brent Charleton joined Steve Darling from Proactive to announce the signing of a new royalty-bearing, commercial license agreement with Solve Solutions, a Brazilian food company specializing in the production and sales of premium dried fruits, vegetables, and snack products. Solve Solutions serves both private label brands and consumer packaged goods manufacturers within Brazil and in international markets, making it a strong partner for EnWave's global expansion strategy. As part of the agreement, Solve Solutions has also purchased one of EnWave's 10kW Radiant Energy Vacuum (REV™) machines, which was previously leased under a Technology Evaluation and License Option Agreement. With this purchase, the company will now hold an exclusive license to use EnWave's patented REV™ technology for drying select fruits, vegetables, and cheese products within Brazil. Under the terms of the deal, Solve Solutions will pay EnWave a royalty structure in line with other existing licensees. In addition, Solve Solutions is required to purchase a large-scale REV™ machine within six months of the commercial license's effective date in order to maintain exclusivity, as well as remit minimum royalty payments on an ongoing basis. Charleton emphasized that EnWave intends to work closely with Solve Solutions to support product development and ensure the successful commercialization of premium dried food products in Brazil and beyond. By leveraging REV™ technology, Solve Solutions will be able to deliver shelf-stable, nutrient-rich products that appeal to health-conscious consumers while differentiating itself in a competitive global food marketplace. #proactiveinvestors #enwavecorporation #tsxv #enw #DehydrationTech #VacuumMicrowave #RoyaltyBusinessModel #BluechipClients #FoodTech #BusinessNews #Investing #RadiantEnergyVacuum #Agritech #Procescir #DehydrationTechnology #FoodInnovation #SupplyAgreement #InvestmentNews #ProactiveInvestors #microdried

    ReElement inks long-term rare earth offtake deal with POSCO International America to bolster supply

    Play Episode Listen Later Sep 30, 2025 4:19


    American Resources Corp CEO Mark Jensen joined Steve Darling to announce a major long-term offtake partnership with POSCO International America Corp, a global leader in steel, magnetic materials, and advanced industrial solutions. The collaboration will unite ReElement's cutting-edge chromatographic separation and purification platform with POSCO's deep expertise in materials science, large-scale deployment, and its extensive relationships across the global automotive and industrial supply chains. Together, the companies will work to establish a scalable, secure, and sustainable supply chain for high-purity rare earth elements, which are indispensable to defense, clean energy, electric vehicles, advanced semiconductors, and emerging AI-driven technologies. Jensen explained that the agreement reflects both companies' long-term commitment to developing resilient and transparent rare earth supply chains that meet the surging demand for critical minerals. As part of the partnership, ReElement and POSCO will form a joint taskforce dedicated to securing diverse global feedstock streams—including mixed rare earth concentrate, magnet manufacturing waste, and end-of-life scrap magnets—to ensure a reliable input pipeline for purification and refining. The offtake agreement includes an initial targeted supply of purified, separated rare earth oxides—specifically dysprosium, yttrium, terbium, and neodymium-praseodymium. The deal anticipates scaling production to over 3,000 metric tons through 2030, representing a transformative step toward meeting the world's growing demand for magnet-grade rare earth elements. Beyond its commercial significance, the partnership also reinforces the strategic alliance between the United States and the Republic of Korea, aligning with global efforts to reduce dependency on limited and politically sensitive supply sources. By securing stable access to rare earths, this initiative directly supports national defense readiness, clean energy independence, and the advancement of next-generation technologies that underpin modern economies. #proactiveinvestors #americanresourcescorporation #nasdaq #arec #SustainableMining, #MineralRefining, #RecyclingInnovation, #CriticalMinerals, #RareEarthRecycling, #EVRecycling, #BatteryRecycling, #princialminerals #adamjohnson #RareEarths #EWasteRecycling #ReElement #CriticalMinerals #SustainableTech #MagnetRecycling #TechInnovation #GreenSupplyChain #ElectrifiedMaterials

    Immunic CMO on CALLIPER MS trial results at ECTRIMS

    Play Episode Listen Later Sep 30, 2025 9:24


    Immunic Inc (NASDAQ:IMUX) chief medical officer Dr Andreas Muehler talked with Proactive's Stephen Gunnion about the company's presence at ECTRIMS - the world's largest conference focused on multiple sclerosis research and treatment - including the oral presentation and the late-breaking poster on its phase 2 CALLIPER trial results of vidofludimus calcium in progressive multiple sclerosis (MS). Muehler explained that the CALLIPER trial demonstrated a medically relevant signal for prevention of disability progression in both primary progressive MS (PPMS) and non-active secondary progressive MS (SPMS) populations. He highlighted that unlike most approved therapies, the trial results were not driven by residual inflammatory activity, but instead pointed to a potential neuroprotective effect through Nurr1 activation. “CALLIPER really showed a medically relevant signal for disability … it was a very consistent signal in this trial,” he said. He added that vidofludimus calcium showed a 2.8 times increase in disability improvement events compared with placebo and maintained a strong safety and tolerability profile with no new safety signals. Beyond CALLIPER, Immunic also presented three additional posters, including phase 2 long-term extension data in relapsing-remitting MS, showing that more than 90% of patients remained free from disability worsening after over three years of treatment. The company also shared new preclinical findings that further support vidofludimus calcium's neuroprotective mechanism. Looking ahead, Muehler said regulatory discussions for a potential phase 3 trial in progressive MS are ongoing, while the next major milestone will be from the fully enrolled ENSURE phase 3 trials in relapsing MS, which are expected to deliver results in 2026. For more videos, visit Proactive's YouTube channel. Don't forget to like this video, subscribe to our channel, and enable notifications for future updates. #Immunic #MultipleSclerosis #MSResearch #ECTRIMS2025 #ClinicalTrials #ProgressiveMS #RelapsingMS #VidofludimusCalcium #BiotechNews #Neuroprotection

    Coinsilium boosts balance sheet with Forza Bitcoin, eyes $YELLOW token launch

    Play Episode Listen Later Sep 30, 2025 11:13


    Coinsilium Group Limited (AQSE:COIN, OTCQB:CINGF) CEO Eddy Travia and CFO Ben Proffitt talked with Proactive's Stephen Gunnion about the company's interim results, treasury strategy and future outlook. Proffitt outlined the financial transformation driven by the launch of Forza Bitcoin, which raised approximately £17 million over the summer. Around 182 Bitcoin have now been added to the company's treasury, leading to a significant rise in digital assets on the balance sheet. “Our Bitcoin value on the balance sheet moved from around £0.5 million to £6 million,” Proffitt stated, with cash reserves also increasing from £400,000 to £3.5 million. Travia said the Bitcoin treasury forms a foundational asset base but clarified that Coinsilium remains fundamentally a blockchain venture builder and investor. He noted that many of the company's investments are held at cost due to their early-stage nature, but expects token launches to begin unlocking value. On this point, Proffitt discussed the Yellow Network's upcoming $YELLOW token launch. Once live, the tokens will provide market-based valuations, enabling Coinsilium to reflect fair value in its portfolio. Looking ahead, Travia highlighted three major trends for 2026: the tokenisation of real-world assets, greater adoption of stablecoins, and evolving regulations opening the door to broader crypto adoption. “AI will play a role in the automation of crypto trading,” he added. For more videos like this, visit Proactive's YouTube channel. Don't forget to like this video, subscribe, and enable notifications so you never miss an update. # Coinsilium #BitcoinTreasury #ForzaBitcoin #YellowToken #CryptoInvestment #BlockchainVenture #Stablecoins #Tokenisation #CryptoTrading #RealWorldAssets #CryptoPortfolio #DigitalAssets #CryptoRegulation #Layer3Technology #ProactiveInvestors

    EnergyPathways CEO on MESH project gaining key UK backing; latest developments

    Play Episode Listen Later Sep 30, 2025 5:30


    EnergyPathways PLC (AIM:EPP) CEO Ben Clube talked with Proactive's Stephen Gunnion about the UK government's designation of the company's flagship MESH project as “nationally significant” — a major milestone under the Planning Act 2008. Clube explained that this classification helps streamline the planning and approval process, accelerating the project's timeline with a view to being operational by 2030. The MESH project is central to the UK's Clean Power 2030 goals, offering both long-duration energy storage and low-cost hydrogen production. Clube emphasised that “we think we can produce hydrogen at the lowest cost relative to two other technologies available to the UK market.” EnergyPathways has secured key partnerships with Siemens Energy, Costain, Zenith Energy, Hazar Group, and KBR Inc., each contributing to the integrated clean energy system — including compressed air energy storage and methane pyrolysis hydrogen production. Siemens is a core technology partner for energy storage, while Hazar and KBR support hydrogen development. Clube also discussed recent capital raised from investors and directors, confirming that the company has now entered the FEED (Front-End Engineering Design) stage. “There's a lot of demand, we think, to backing the company through FEED and through the development cycle,” he added. The company expects several upcoming milestones as it navigates the Planning Act process and advances project approvals. For more interviews like this, visit Proactive's YouTube channel. Don't forget to like this video, subscribe, and turn on notifications for updates. #EnergyPathways #HydrogenProduction #CleanEnergyUK #MESHProject #BenClube #EnergyStorage #SiemensEnergy #MethanePyrolysis #NetZeroUK #FEEDstage #WindCurtailment #CompressedAirStorage #ProactiveInvestors #CleanPower2030

    Trust Stamp highlighted by Intel for AI-driven, privacy-first digital identity verification platform

    Play Episode Listen Later Sep 30, 2025 3:40


    Trust Stamp Chief Technical Officer Scott Francis joined Steve Darling from Proactive to announce that the company has been featured in a Partnership Brief published by Intel Corporation, highlighting Trust Stamp's cutting-edge privacy-first, real-time identity verification platform powered by AI-optimized biometrics. The Trust Stamp Protect™ platform leverages Intel® Xeon Scalable Processors® to deliver high-throughput, low-latency identity verification at scale, with deployment capabilities across cloud, edge, and hybrid infrastructures. By utilizing quantized AI models optimized through Intel's OpenVino™ toolkit, the platform reduces model size and latency, enabling deployment even in resource-constrained environments without compromising performance or security. Francis shared with Proactive that Trust Stamp's AI-driven identity platform redefines traditional authentication methods. Through advanced facial biometrics, liveness detection, and privacy-preserving tokenization, the platform replaces vulnerable one-time passwords (OTPs) with a seamless, selfie-based experience. Real-time 1:1 identity matching is performed using irreversibly transformed identity tokens (IT2™), ensuring user privacy while maintaining robust security. Designed for scalability and speed, Trust Stamp Protect™ minimizes latency and model size through AI quantization, enabling secure, frictionless authentication across industries such as digital banking, fintech, and KYC/AML workflows. Layered data protection and spoof-resistant verification further empower financial institutions to reduce fraud, enhance regulatory compliance, and maintain customer trust without compromising privacy. Francis emphasized that the collaboration with Intel demonstrates the platform's ability to meet the growing demand for secure, privacy-first identity solutions, enabling organizations to scale authentication seamlessly across diverse environments and digital services. #proactiveinvestors #truststamp #nasdaq #idai #IdentityTech #DigitalIdentity #Fintech #GhanaID #SouthKoreaStartup #AsiaExpansion #KStartupChallenge #FinancialServices #Biometrics #TechExpansion #ProactiveInvestors #AndrewGowasack #scottfrancis #intel #truststampprotect

    Poolbeg Pharma CEO on active H1, POLB 001 & GLP-1 trial plans

    Play Episode Listen Later Sep 30, 2025 8:14


    Poolbeg Pharma PLC (AIM:POLB, OTC:POLBF) CEO Jeremy Skillington talked with Proactive's Stephen Gunnion about the company's interim results and key clinical milestones. Skillington highlighted that Poolbeg ended June with £10 million in cash, supported by an upsized and oversubscribed £4.87 million fundraise earlier in the year. He said this extends the company's cash runway into 2027, providing a strong foundation for advancing upcoming trials. One of the company's main focuses is POLB 001, which is being developed to prevent cytokine release syndrome in patients undergoing cancer immunotherapies. “We expect to have interim data in the summer of 2026 that we can start sharing with our pharma colleagues,” Skillington noted. The trial will take place at the Christie NHS Foundation Trust under Dr Emma Searle, with support from Accelerating Clinical Trials (ACT). Skillington also discussed Poolbeg's oral GLP-1 program, developed in partnership with AnaBio Technologies. This program uses an encapsulation technology to allow oral delivery of GLP-1, currently given mostly by injection. A rapid proof-of-concept trial is planned under Prof Carel le Roux at the University of Ulster, with data expected in the first half of 2026. Looking ahead, Skillington said Poolbeg is entering a “catalyst-rich period” with multiple updates expected that could attract pharmaceutical partners. For more interviews and updates, visit Proactive's YouTube channel. Don't forget to like this video, subscribe, and turn on notifications to stay informed. #PoolbegPharma #POLB001 #GLP1 #CancerImmunotherapy #Biotech #ClinicalTrials #Oncology #ObesityTreatment #DrugDevelopment #PharmaInnovation

    Active Energy treasury adviser on $100k allocation to trending altcoins

    Play Episode Listen Later Sep 30, 2025 8:13


    Active Energy Group PLC treasury strategy adviser Adrian Rowles talked with Proactive about the company's initial $100,000 allocation into a basket of trending digital assets and how that short-term programme complements longer-term energy and AI hosting initiatives. Rowles explained that Active Energy maintains some Bitcoin in its longer-term treasury, but the new, tactical allocation focuses on highly liquid alternatives with strong community momentum, such as Solana, Binance Coin and Dogecoin. He noted the timing also reflects caution around a major Bitcoin options expiry and the associated volatility. “It just seems a very good place to dip our toe in the water and start to position some of this money, and I'm anticipating the fourth quarter is going to be exceptionally strong,” Rowles said. Rowles outlined an institutional-style risk framework for the 30–90-day trading approach, including sizing, exposure, timing and duration limits aimed at optimising returns while limiting downside. He also set out how the trading activity sits alongside Active Energy's pipeline of AI power and hosting projects. The company has “projects in the pipeline… securing in excess of £10 million in revenue” and is in advanced stages of implementation, he said. Rowles added that Active Energy has identified surplus energy that can be sold to third parties amid tight grid conditions driven by AI demand. He cited a 30MW pipeline, describing it as power sufficient for a small town, and shared a constructive fourth-quarter outlook after a “red September” for crypto. For more interviews like this, visit Proactive's YouTube channel. If you found this useful, please like, subscribe, and turn on notifications for future content. #ActiveEnergyGroup #AdrianRowles #CryptoTreasury #Altcoins #Solana #BNB #Dogecoin #Bitcoin #AIHosting #EnergyInfrastructure #TreasuryStrategy #Q4Outlook #30MW

    ReElement expands Noblesville facility 141%, boosting supply of ultra-pure critical defense minerals

    Play Episode Listen Later Sep 26, 2025 4:15


    American Resources Corp CEO Mark Jensen joined Steve Darling to announce a major capacity expansion at its Noblesville, Indiana critical mineral refining facility, operated through its subsidiary ReElement Technologies. The expansion increases the site's footprint by 141%, bringing it to more than 16,500 square feet and providing near-term refining capacity of over 200 metric tons per year of ultra-pure separated defense elements and rare earth oxides. Jensen explained that this investment significantly enhances ReElement's ability to deliver critical minerals essential to the defense and advanced technology sectors. Among the materials targeted for production are yttrium, germanium, gadolinium, gallium, terbium, samarium, dysprosium, and antimony — all of which are designated as vital to U.S. national security and high-performance applications. The Noblesville facility now stands as a key near-term supplier while the company's larger-scale Marion Supersite continues to advance toward commissioning. As part of this expansion, ReElement recently installed nine additional separation columns, alongside critical equipment such as its state-of-the-art ICP-MS machine, ensuring the facility can consistently produce materials of 99.999% purity at commercial scale. Notably, the company has managed to execute this expansion while maintaining uninterrupted daily operations, demonstrating its operational efficiency and scalability. Meanwhile, at the Marion Supersite, ReElement has either ordered, identified, or begun installing more than 60% of the equipment required for the site's initial contracted growth phase. Once operational, Marion will provide large-scale refining capacity across multiple critical materials, including magnet-grade rare earths, battery metals, antimony, and additional defense elements. Jensen emphasized that the Noblesville expansion is an important step in strengthening the United States' domestic critical minerals supply chain. By scaling up both near-term and long-term refining capacity, ReElement is positioning itself as a cornerstone provider of sustainable, onshore solutions for defense, clean energy, and advanced manufacturing markets. #proactiveinvestors #americanresourcescorporation #nasdaq #arec #SustainableMining, #MineralRefining, #RecyclingInnovation, #CriticalMinerals, #RareEarthRecycling, #EVRecycling, #BatteryRecycling, #princialminerals #adamjohnson #RareEarths #EWasteRecycling #ReElement #CriticalMinerals #SustainableTech #MagnetRecycling #TechInnovation #GreenSupplyChain #ElectrifiedMaterials

    B HODL CEO and CFO on building revenue and value with Bitcoin following AQSE listing

    Play Episode Listen Later Sep 26, 2025 7:27


    B HODL PLC (AQSE:HODL) CEO Freddie New and CFO David Boylan talked with Proactive about the company's listing on the Aquis Exchange and its strategy as a Bitcoin treasury and services business. New explained that B HODL aims to take advantage of both Bitcoin's store of value and its potential as a medium of exchange. New said: “What really, really excites me about B Hodl PLC is not simply the treasury… it's that opportunity to show what Bitcoin can do.” New outlined the company's ambition to generate revenue from Bitcoin through operational strategies like providing liquidity to the Lightning Network. Boylan also emphasised transparency as a cornerstone of the company's investor approach. “Bitcoin is still scary to people… we're basically staking our reputations and service behind Bitcoin,” he said. B HODL plans to provide accessible data and reporting to help demystify Bitcoin for investors. New discussed the company's strong management team, which includes experience from CoinCorner, PayPal, Baillie Gifford, and other financial services and crypto institutions. He also noted that while the business is listed and fully compliant with UK regulations, many of its operational activities remain outside the scope of traditional regulation. Boylan added that the company will track traditional treasury metrics like NAV and Bitcoin yield, while also highlighting new KPIs tied to Bitcoin utility and revenue generation. For more interviews like this, visit Proactive's YouTube channel. Don't forget to like this video, subscribe to the channel, and enable notifications for future content. #Bitcoin #BHodl #CryptoTreasury #LightningNetwork #CryptoInvesting #BitcoinRevenue #BitcoinUK #AquisListing #CryptoTransparency #DigitalAssets

    Poolbeg Pharma kicks off POLB001 Phase 2a trial with specialist partner

    Play Episode Listen Later Sep 26, 2025 5:25


    Poolbeg Pharma PLC (AIM:POLB, OTC:POLBF) CEO Jeremy Skillington and principal scientist Liam Tremble talked with Proactive's Stephen Gunnion about the company's upcoming Phase 2a trial for POLB001. Tremble explained that Poolbeg has partnered with Accelerating Clinical Trials (ACT) in the UK to conduct the study, which will be led by Dr Emma Searle at the University of Manchester and the NHS Christie Foundation Trust. The Christie is one of Europe's largest cancer centres, treating more than 60,000 patients annually, and will act as the lead site. Tremble emphasised, “We've been really fortunate and feel quite blessed that we found a massive amount of interest in participating on this trial.” The trial will be a single-arm, open-label Phase 2a study involving approximately 30 patients. With sufficient supply of both POLB001 and the required bispecific antibody, Poolbeg expects to generate data throughout 2026, with a focus on safety and efficacy. Skillington noted the wider potential for POLB001 in cancer immunotherapy. He said that reducing cytokine release syndrome could allow treatments to move beyond specialist centres into community hospitals. “We feel POLB001 can do that,” he added, describing the market opportunity as greater than $10 billion. He also highlighted that the company holds FDA orphan drug designation for POLB001 and has a cash runway into 2027, positioning Poolbeg to achieve multiple milestones and advance partnering discussions. For more interviews and updates, visit Proactive's YouTube channel. Don't forget to like this video, subscribe to the channel, and enable notifications for future content. #PoolbegPharma #POLB001 #CancerResearch #Immunotherapy #ClinicalTrials #Biotech #Oncology #BloodCancer #PharmaNews #DrugDevelopment

    Arecor CEO on AT278 partnership with Sequel Med Tech, $11m royalty funding deal and interim results

    Play Episode Listen Later Sep 25, 2025 8:32


    Arecor Therapeutics PLC (AIM:AREC) CEO Sarah Howell talked with Proactive's Stephen Gunnion about the company's strategic updates, including a key partnership with Sequel Med Tech and a new royalty financing agreement with Ligand Pharmaceuticals. Howell explained that Arecor has partnered with Sequel, a US-based insulin pump device company, to advance its lead program AT278, described as “the only ultra-concentrated, ultra-rapid acting insulin in development.” Together, the companies will co-develop AT278 in combination with Sequel's twiist automated insulin delivery system, with phase 2 clinical trial preparations already underway. Each party has committed up to $1.3 million to fund development, with trial readiness targeted for 2026. Discussing the rationale for the partnership, Howell said Sequel “really bring innovation to the table, significant experience in terms of patient need, the market and also clearly commercialisation.” She noted the potential for AT278 and the Twist system to extend insulin pump wear times and support future miniaturisation, expanding access for people with diabetes. In addition, Arecor announced a royalty financing deal with Ligand Pharmaceuticals, securing up to $11 million in non-dilutive funding linked to partnered products using its Arestat technology. Howell said this extends the company's cash runway into the first half of 2027, while supporting development of AT278 and its oral peptide delivery platform. For more interviews and updates, visit Proactive's YouTube channel. Don't forget to like this video, subscribe to the channel, and enable notifications for future content. #ArecorTherapeutics #AT278 #DiabetesCare #InsulinPump #SequelMedTech #TwistSystem #DiabetesTechnology #BiotechNews #PharmaUpdates #ClinicalTrials

    Gunnison Copper makes first copper sales from Johnson Camp, bolstering U.S. supply chain

    Play Episode Listen Later Sep 25, 2025 4:27


    Gunnison Copper Corp SVP and CFO Craig Hallworth joined Steve Darling from Proactive to announce a major operational milestone for the company — the first commercial sales of pure copper cathode from its fully operational Johnson Camp Mine (JCM) in southeast Arizona. The mine, which has the capacity to produce up to 25 million pounds of copper cathode annually, has now transitioned into revenue generation following successful commissioning. Hallworth reported that on September 15, Gunnison completed its inaugural copper sales, delivering a total of 225,371 pounds of finished copper cathode. The copper was sold at an average realized price of US$4.64 per pound, generating gross proceeds of approximately US$1.05 million. These sales represent the first “Made-in-America” copper cathode from JCM delivered directly into domestic markets, marking a significant contribution to strengthening the U.S. copper supply chain. Looking ahead, Gunnison Copper expects to begin production using Nuton's innovative bio-leaching technology later this year. Nuton, a venture of Rio Tinto, has selected JCM as the first commercial-scale deployment site for this breakthrough technology, which is designed to deliver improved recovery rates while reducing environmental impact. Production at Johnson Camp Mine officially began during the final week of August 2025, ahead of schedule and with an exemplary health and safety record. The mine's output is entirely U.S.-produced, directly supporting critical industries tied to energy independence, advanced manufacturing, clean technology, and national defense. Hallworth emphasized that this milestone is not only a key achievement for Gunnison Copper but also a significant development for domestic copper production, as the company continues to build value while contributing to America's strategic resource independence. #proactiveinvestors #gunnisoncoppercorp #tsx #gcu #otcqb #gcumf #CopperMining #USMining #CopperProject #CopperMining #GunnisonCopper #NutonTechnology #USMining #CriticalMinerals #CopperProduction #MiningStocks #NaturalResources #ElectricEconomy #CopperPrices #FreeCashFlow #JohnsonCampMine

    Aftermath Silver outlines Q4 2025 drilling plans at Challacollo silver-gold project in N. Chile

    Play Episode Listen Later Sep 25, 2025 2:54


    Aftermath Silver CEO Ralph Rushton joined Steve Darling from Proactive to provide an update on the company's exploration strategy for its flagship Challacollo Silver-Gold Project, located in Region 1 of northern Chile. The property hosts a low-sulphidation epithermal Ag-Au vein system with a significant established silver resource, making it one of the more prospective undeveloped silver projects in the region. Rushton shared that Aftermath plans to initiate a 7–10 hole diamond core drilling program in Q4 2025, targeting up to 2,000 meters of total drilling. Previous drilling campaigns primarily focused on the Loló́n Vein, the principal structure on the property, which has been drilled to approximately 200 meters below surface. Importantly, the oxidation zone bottoms at around 200 meters, and beyond this depth the mineralized structures remain open and largely untested. Notably, gold and base metal grades have been observed to increase at depth, further enhancing the project's exploration potential. The upcoming drilling campaign has three key objectives to expand the current resource by extending known veins down dip and along strike. Test additional veins—both historically identified but untested, as well as newly interpreted structures within Aftermath's land package and twin select RC holes to collect supplementary geological and metallurgical data, strengthening the company's understanding of orebody characteristics and potential processing options. Rushton emphasized that this program is designed to both de-risk the existing resource and unlock new exploration upside, positioning Challacollo as a cornerstone asset in Aftermath's growing silver-gold portfolio. #proactiveinvestors #aftermathsilverltd #tsxv #aag #otcqx #aagff #mining #SilverMining, #BerenguelaProject, #Mining #Silver #Copper #Manganese #Peru #DrillingResults #BatteryMetals #ResourceModel #Investing

    Algernon Pharma secures $4M non-dilutive deal to launch U.S. neuroimaging clinics for Alzheimer's

    Play Episode Listen Later Sep 25, 2025 5:34


    Algernon Pharmaceuticals CEO Christopher Moreau joined Steve Darling from Proactive to announce a major milestone in the company's transition toward specialized healthcare services. Algernon has signed a definitive equipment purchase and financing agreement with Catalyst MedTech for four U.S. FDA-cleared Oncovision CareMiBrain brain-specific Positron Emission Tomography (PET) scanner systems. These systems will be deployed in Algernon's first four planned neuroimaging medical clinics in the United States. The agreement, valued at over CAD $4 million, is a non-dilutive transaction and also includes provisions for Algernon to acquire an additional six scanner systems on an adjusted cost basis to support the establishment of future clinics. This marks an important step in scaling Algernon's clinic network across North America. Moreau also highlighted that Algernon intends to rebrand as Algernon Health, a move that reflects the company's strategic pivot into the Alzheimer's Disease diagnostic market. The company's neuroimaging clinics will be the first in the U.S. dedicated exclusively to brain-specific PET imaging, focusing on the early detection of Alzheimer's Disease. In addition, the facilities will offer advanced PET imaging for other neurological conditions, including various forms of dementia, epilepsy, neuro-oncology, and movement disorders. Algernon plans to work closely with neurologists, geriatricians, primary care physicians, and other healthcare professionals to generate patient referrals and ensure its clinics are well-integrated into the broader medical ecosystem. The need for brain-specific imaging capacity in the U.S. is significant. While PET/CT scanners exist nationwide, the vast majority — 45% of which are located in hospitals — are prioritized for oncology and cardiology diagnostics, leaving limited availability for timely brain scans. This shortage is particularly pressing given the emerging demand for Alzheimer's diagnostic tools and therapies. Each Alzheimer's PET brain scan at Algernon's planned clinics will cost approximately US$5,000, a service covered in the U.S. by private insurers, Medicare, and Medicaid. By establishing a dedicated network of clinics, Algernon aims to address this critical gap in diagnostic services and position itself at the forefront of the rapidly growing Alzheimer's care market. #proactiveinvestors #algernonpharmaceuticalsinc #cse #agn #otcqb #agnpf #alzheimerdisease #demetia

    New Era Energy & Digital completes Phase 1 engineering for Texas data centers, paving 1 GW AI campus

    Play Episode Listen Later Sep 25, 2025 5:54


    New Era Energy & Digital CEO Will Gray joined Steve Darling from Proactive to announce the successful completion of Phase One engineering for Texas Critical Data Centers LLC, the company's flagship data center and power development project located in the heart of the Permian Basin of West Texas and southeastern New Mexico. TCDC is structured as a 50/50 joint venture between New Era and Sharon AI, Inc., combining expertise in energy infrastructure and artificial intelligence. Phase One engineering included a comprehensive series of environmental studies — all of which successfully passed review — along with detailed feasibility assessments for data center development and load studies to evaluate long-term energy requirements. Gray confirmed that the next step will be filing a large load interconnection application, a key milestone that will set the foundation for securing reliable energy delivery to the site. Based on the current project timeline, New Era anticipates that initial power delivery could begin as early as 2027. The TCDC campus is being designed to ultimately scale to 1 gigawatt of power capacity, positioning it as one of the largest AI-optimized data center complexes in North America. This ambitious design underscores the growing demand for next-generation data infrastructure capable of supporting artificial intelligence workloads, cloud computing, and high-performance computing applications. The project is further strengthened by previously announced partnerships that will establish behind-the-meter power islands, ensuring reliable energy delivery while maintaining compliance with Texas Senate Bill 6. This legislation, which directly affects large energy consumers like data centers on the Electric Reliability Council of Texas (ERCOT) grid, requires new operational models for balancing grid reliability with rising power demands. Gray emphasized that completing Phase One engineering validates the constructability and scalability of the TCDC project, providing a clear pathway toward developing a premier energy and data hub that will meet the needs of both AI-driven industries and broader digital infrastructure markets. #proactiveinvestors #neweraheliuminc #nasdaq #nuai #oil #gas #perimianbasin #HeliumProduction #NaturalGas #DataCenters #AIInfrastructure #PecosSlope #VerticalIntegration #EnergyMarkets #PermianBasin #Semiconductors #PowerGeneration #ProactiveInvestors

    NEXE Innovations expands coffee portfolio with 4 new SKUs, targeting broader market reach

    Play Episode Listen Later Sep 25, 2025 2:58


    NEXE Innovations President Ash Guglani joined Steve Darling from Proactive to announce an exciting expansion of the company's product portfolio, unveiling the launch of four new coffee SKUs in collaboration with a leading North American distributor specializing in office coffee services and retail channels. Since beginning this partnership in February 2025, NEXE has seen consistent customer engagement through recurring orders, underscoring strong market demand for its products. The first SKU in this launch is a seasonal pumpkin-flavored coffee pod, of which the company has already produced and distributed six pallets across U.S. and Canadian markets. Looking ahead, NEXE is actively developing three additional SKUs — decaf, vanilla, and bananas foster — which are expected to hit the market in the near term. These offerings are designed to cater to diverse consumer preferences while maintaining the company's focus on high-quality, innovative coffee experiences. Beyond these initial launches, NEXE and its distribution partner plan to introduce at least ten more SKUs over the coming months. At the same time, the company is in advanced discussions with potential new partners to expand its distribution network, aiming to secure broader market access and reach more consumers across North America. NEXE remains dedicated to sustainable innovation, particularly in packaging and product development. Through strategic partnerships and environmentally conscious initiatives, the company continues to position itself as a forward-thinking leader in the coffee industry, blending quality, variety, and sustainability. #proactiveinvestors #nexeinnovationsinc #tsxv #nexe #otc #nexnf #Sustainability #CoffeePods #EcoFriendlyProducts #Manufacturing #PatentTechnology #StrategicPartnerships #AshGuglani #ProactiveInvestors #GreenTechnology

    Resourcing Tomorrow: mining's future takes centre stage this December

    Play Episode Listen Later Sep 25, 2025 6:34


    Resourcing Tomorrow divisional director Andrew Thake talked with Proactive's Stephen Gunnion about what makes this year's event a pivotal moment for the global mining industry. Thake outlined how the conference brings together over 2,100 attendees, more than 175 mining companies, 500+ investors and representatives from over 40 governments. “We have really, really crucial conversations that set direction for the future of the industry,” he said. Key topics in 2025 include geopolitics, defence, and the impact of recent M&A activity, including the Anglo-Teck deal. Thake noted the return of commodity price strength, particularly in gold, as a driver for discussion. ESG and sustainability also remain on the agenda despite recent geopolitical pressures. Special focus sessions include keynote addresses from NATO, as well as unique panels featuring voices such as advertising executive Martin Sorrell. Roundtable discussions—under Chatham House rules—cover sensitive subjects including Ukraine's reconstruction and deep-sea mining, with notable participants such as Dominic Raab and Geoffrey Pyatt. Technology Pitch Battles return to spotlight innovation, offering startups the chance to present solutions directly to miners and investors. The event also coincides with the inaugural London Mining Week, fostering wider collaboration through events like the Women in Mining Lounge and the Oxford Mining Club. Resourcing Tomorrow takes place from 2–4 December at the Business Design Centre in Islington, London. For more interviews like this, head to Proactive's YouTube channel. Don't forget to like this video, subscribe to our channel, and enable notifications so you never miss an update. #ResourcingTomorrow #MiningConference #AndrewThake #MiningInnovation #GeopoliticsAndMining #SustainableMining #MiningESG #MiningInvestment #TechnologyInMining #LondonMiningWeek #ProactiveInvestors

    Tertiary Minerals MD on latest drill results at Mushima North; confirmation of wide silver zones

    Play Episode Listen Later Sep 25, 2025 3:33


    Tertiary Minerals PLC (AIM:TYM, OTC:TTIRF) managing director Richard Belcher talked with Proactive's Stephen Gunnion about the latest drill results from the Mushima North project in Zambia. The company confirmed a 350 by 300 metre mineralised footprint, with results that remain open to the north, south, and at depth. Belcher described the new findings as “very significant for us,” noting the consistent wide intervals, near-surface mineralisation, and the presence of higher-grade silver zones. He explained that the results support Tertiary's working model for an open-pit mining approach, highlighting Zambia's long history of successful open-cast mining as a strong precedent. Mineralisation has been identified within just two metres of the surface, further reinforcing the low-cost extraction potential. Looking ahead, Belcher outlined key upcoming milestones, with around half of the drilling results still to be released. He emphasised that investors can expect further updates from multiple drill batches, as well as initial metallurgical and mineralogical studies that will determine whether the mineralisation is amenable to low-cost processing. Mushima North is a high-priority project within Tertiary's Zambian exploration portfolio. The company is also advancing its interests at Konkola West and Mukai through joint ventures, while exploring opportunities to progress projects in Nevada, USA, potentially through new partnerships. For more updates on Tertiary Minerals and other mining companies, visit Proactive's YouTube channel. Don't forget to like this video, subscribe, and turn on notifications to stay informed. #TertiaryMinerals #ZambiaMining #SilverExploration #MushimaNorth #DrillResults #MiningInvesting #CopperGold #MiningNews #ProactiveInvestors

    Anglo Asian: Gilar & Demirli drive H1 production surge

    Play Episode Listen Later Sep 25, 2025 11:48


    Anglo Asian Mining Plc (LSE:AAZ, OTC:AGXKF) vice president Stephen Westhead takes Proactive's Stephen Gunnion through the company's latest interim results and recent operational progress. Westhead highlighted a transformational period for the company, including the successful commencement of production at the Gilar and Demirli mines within the Gedabek Contract Area. Gilar entered production in May and is already contributing significant copper and gold grades. Demirli has now begun development and is expected to produce approximately 4,000 tonnes of copper in concentrate by the end of 2025. The company reported a return to profitability, with profit before tax of US$7.1 million, and revenues more than tripling to nearly $41 million. Westhead noted, “We managed to return to profitability and achieved $7.1 million profit before tax. Our revenues have more than tripled to nearly $41 million.” He explained that Anglo Asian is transitioning toward becoming a mid-tier copper-focused producer, supported by its existing operations at Gedabek, Gilar, and Demirli, along with future development of the Xarxar and Garadag copper projects. The company also recently experienced the highest share price in its history, underscoring strong market confidence. Anglo Asian expects continued momentum in the second half of the year with production ramp-ups and exploration studies underway. Visit Proactive's YouTube channel for more videos. Don't forget to like this video, subscribe to the channel, and enable notifications for future content. #AngloAsianMining #CopperMining #GoldMining #GilarMine #DemirliMine #MiningInvesting #CopperStocks #GoldStocks #AIMStocks #ResourceDevelopment #MineralExploration #MiningUpdate #ProactiveInvestors

    HIVE Digital hits 20 EH/s global Bitcoin capacity as Paraguay Phase 3 moves toward completion

    Play Episode Listen Later Sep 24, 2025 7:03


    Hive Digital Technologies CEO Aydin Kilic joined Steve Darling from Proactive to announce a significant achievement for the company — surpassing 20 Exahash per second (EH/s) of global Bitcoin mining capacity. This milestone comes on the heels of the continued rollout of advanced ASIC miners at HIVE's Phase 3 Valenzuela facility in Paraguay. Kilic explained that Phase 3 marks the company's third major 100-megawatt project in Paraguay, powered entirely by renewable hydroelectric energy from the world-renowned Itaipu Dam. This expansion underscores HIVE's long-term commitment to building sustainable, environmentally responsible Bitcoin mining operations while scaling its global footprint. The results so far have been substantial. HIVE has grown its hashrate by approximately 233% year-to-date and is currently producing around nine Bitcoin per day at a fleet efficiency of 18 Joules per Terahash (J/TH). Importantly, the company is achieving a healthy 55% mining margin after electricity costs, demonstrating the profitability of its green-energy-powered infrastructure. At present, HIVE's operations account for roughly 2% of the entire Bitcoin network, based on the current network difficulty of 142 trillion. With Phase 3 construction now largely complete and installations advancing ahead of schedule, HIVE recently surpassed its interim goal of 19 EH/s, ultimately pushing the company's global fleet to 20 EH/s. This marks a critical milestone in its strategic roadmap to reach 25 EH/s by U.S. Thanksgiving later this year. Looking ahead, once Phase 3 is fully completed, HIVE expects its daily Bitcoin production to increase to approximately 12 BTC, while further improving efficiency to around 17.5 J/TH. This scaling effort positions the company to strengthen its role as one of the leading players in sustainable Bitcoin mining worldwide. #proactiveinvestors #hivedigitaltechnologieslet #tsxv #hive #nasdaq #hive #CryptoMining #GreenEnergy #BitcoinMining #ParaguayMining #DataCenter #Exahash #S21Miners #DigitalAssets #ProactiveInvestors

    Arizona Gold & Silver advances Silverton gold-antimony project in Nevada after federal approval

    Play Episode Listen Later Sep 24, 2025 2:19


    Arizona Gold and Silver CEO Mike Stark joined Steve Darling from Proactive to outline the company's next steps in advancing the Silverton gold-antimony project, strategically located in Nye County, Nevada. The project sits immediately north of U.S. Highway 6, approximately halfway between Tonopah and Ely, placing it in a well-established mining region with strong infrastructure access. Stark highlighted the growing importance of antimony, which is currently trading at approximately US$57.50 per pound and has been officially designated a critical mineral by the U.S. government for its role in defense and strategic applications. Historically, antimony occurrences on the Silverton property had been viewed as a trace-metal signature associated with deeper, blind gold mineralization. However, the current pricing environment, coupled with strong federal support for domestic antimony development, has prompted the company to re-examine this resource with fresh eyes. The Silverton property benefits from an extensive historical database. More than 2,000 rock samples were collected across the property, primarily by Newcrest Resources Inc. between 2002 and 2004. Analysis of this data revealed over 25 surface samples containing more than 1% Sb. 95 surface samples with values above 1,000 ppm Sb. Importantly, these anomalous antimony values are often associated with gold grades ranging between 0.1 and +1.0 grams per tonne, underscoring the potential for both critical mineral and precious metal discoveries. To advance exploration, Arizona Gold & Silver recently submitted a Notice of Intent (NOI) to the U.S. Bureau of Land Management, requesting approval to drill 27 reverse circulation holes from 17 drill pads, along with the construction of supporting access roads. Approval for the NOI was granted on September 18, 2025, clearing the way for the company to begin drilling. Looking ahead, the company plans to entertain joint venture proposals for testing both the antimony-gold zones and magnetotelluric (MT) targets at Silverton. This approach will allow Arizona Gold & Silver to leverage external expertise and capital while continuing to concentrate its own resources on advancing the company's flagship high-grade Philadelphia gold project in Arizona. Stark emphasized that these strategic steps position the company to unlock additional value from its portfolio while maintaining its focus on delivering results at Philadelphia, where strong exploration momentum continues. #proactiveinvestors #arizonagoldandsilverinc #tsxv #azs #otcqb #azasf #GoldExploration #PhiladelphiaProject #MiningNews #JuniorMining #HeapLeach #Metallurgy #ResourceInvesting #GoldStocks #PreciousMetals #MiningNews #GoldExploration #SilverMining #JuniorMining #ArizonaMining #GoldInvesting #DrillResults #MiningInfrastructure #ProactiveInvestors #perryzone #risingfawnzone #Antimony #CriticalMinerals #ArizonaGoldAndSilver #MiningNews #SilvertonProject #GoldExploration #JointVentureOpportunity #NevadaMining #DrillPermit

    Cordiant Digital on Q1 performance, data centre growth plans, BT Ireland and EU expansion

    Play Episode Listen Later Sep 24, 2025 10:51


    Cordiant Digital Infrastructure Management chairman Steven Marshall and Cordiant Digital Infrastructure Ltd (LSE:CORD) CFO Andrew Ewe talked with Proactive's Stephen Gunnion about the company's progress across key projects in Europe. Marshall discussed the performance of Speed Fibre following its acquisition of BT Ireland. He said the integration had gone smoothly and that the business was continuing to strengthen. Attention then turned to Cordiant's Prague Gateway project under CRA. The site has a planned capacity of 26 megawatts and, according to Marshall, is positioned to serve growing demand in the region. He noted that CRA had “successfully qualified for the European Union gigafactory site bid process,” which he described as a significant milestone. Ewe provided updates on Belgium-based Datacenter United, highlighting the group's stable operations and continued customer activity. He also addressed financials, explaining how Cordiant has been managing its balance sheet and ensuring that portfolio companies remain well capitalised. Marshall concluded by outlining the company's focus on infrastructure assets that support digital connectivity across Europe. Visit Proactive's YouTube channel for more videos, and don't forget to give this video a like, subscribe to the channel, and enable notifications for future content. #CordiantDigital #InfrastructureInvestment #DataCenters #Telecoms #SpeedFibre #PragueGateway #DatacenterUnited #EUInfrastructure #ProactiveInvestors

    Creo Medical CEO on 40% revenue growth, Speedboat adoption & outlook

    Play Episode Listen Later Sep 24, 2025 6:16


    Creo Medical Group PLC (AIM:CREO, OTC:CMEOF) CEO Craig Gulliford talked with Proactive's Stephen Gunnion about the company's strong first-half results, which showed revenue rising 40% on the back of wider clinical adoption of its core Speedboat technology. Gulliford explained that growth has been driven by sustained use among existing users, alongside new product derivatives that expand indications across the upper and lower GI tract. He highlighted the recent US clearance of the SpydrBlade device, noting that it is expected to contribute more meaningfully in the second half. Gulliford also discussed the sale of 51% of Creo Medical Europe to Micro-Tech, which delivered £25 million in cash and a profit boost. He said the partnership not only strengthens the balance sheet but also provides opportunities to broaden the product portfolio, improve margins, and expand into the Chinese market. Gulliford confirmed the company now has 232 active users of its core products, with adoption split evenly between Europe and the US. He noted operating costs fell 24%, and losses narrowed significantly. Looking ahead, he said the company is confident in reaching a self-sustaining cash flow position between 2027 and 2028, supported by cost efficiencies, manufacturing partnerships, and additional cash inflows. For more interviews and updates, visit Proactive's YouTube channel. Don't forget to like this video, subscribe, and enable notifications for future content. #CreoMedical #MedicalDevices #HealthcareInnovation #MedTech #GIprocedures #Speedboat #SpydrBlade #MicroTech #MedicalTechnology #ProactiveInvestors

    Trust Stamp unveils zero-knowledge proof breakthrough for privacy-first digital ID, age verification

    Play Episode Listen Later Sep 24, 2025 5:59


    Trust Stamp President Chief Science Officer Norman Poh joined Steve Darling from Proactive to announce a major step forward in digital identity and online safety: the company has introduced Zero-Knowledge Proofs (ZKPs) for remote human presence, an innovation designed to transform how age and identity verification are conducted in digital environments. Dr. Poh presented the breakthrough at “On the Pulse Conversation: Research and Innovation – Current Developments in Biometrics,” an online event hosted by the Biometrics Institute. The advancement responds to growing demand for secure, privacy-first solutions in Know Your Customer (KYC) protocols and age assurance processes, particularly as online fraud and privacy concerns continue to rise. Traditional verification methods often require sharing sensitive personal data, which can be stored, compromised, or misused. They are also vulnerable to credential sharing and “friendly fraud,” where legitimate credentials are used by unauthorized individuals. Trust Stamp's solution—Biometric Bound Credentials (BBCreds)—uses ZKP technology to cryptographically bind age and identity credentials directly to an individual's biometric features, without ever storing biometric templates. This ensures that only the legitimate, physically present individual can access regulated or age-restricted services, dramatically reducing risks while protecting user privacy. The company emphasized that this ZKP-driven approach fundamentally changes remote authentication. Instead of relying on the device as the authenticator, BBCreds authenticate the user themselves, preventing misuse even if a device is shared or compromised. Device unlocking alone is no longer sufficient for access, raising the security bar across industries. By enabling remote human presence and age verification without exposing biometric data, Trust Stamp believes this technology will set a new benchmark in security, compliance, and user trust—particularly for industries that must balance strict regulatory requirements with consumer privacy. #proactiveinvestors #truststamp #nasdaq #idai #IdentityTech #DigitalIdentity #Fintech #GhanaID #SouthKoreaStartup #AsiaExpansion #KStartupChallenge #FinancialServices #Biometrics #TechExpansion #ProactiveInvestors #AndrewGowasack

    Replenish Nutrients grows portfolio with new licensing deal, launches proprietary pellet fertilizer

    Play Episode Listen Later Sep 24, 2025 4:00


    Replenish Nutrients CEO Neil Wiens joined Steve Darling to announce the company has closed a new licensing agreement with MJ Ag Solutions Ltd., a Northern Alberta-based fertilizer distributor, alongside the launch of a proprietary pellet fertilizer product line. As the company gears up for a busy fall season, the new licensing deal enables Replenish's partner to manage manufacturing, with both parties contributing to sales efforts. Importantly, the agreement requires no upfront capital expenditures from Replenish, with working capital obligations shared between the two companies. Initial production runs are set to begin within weeks, with volumes expected to scale to 800 metric tonnes per month, supplementing output from Replenish's Beiseker granulation facility. The pelletized products complement Replenish's existing blended and granulated offerings, delivering equivalent soil health benefits while lowering production costs and simplifying manufacturing. They also provide growers with practical advantages, including easy storage, transport by truck or rail, and broad compatibility with standard farm spreading equipment. Wiens emphasized that this expansion represents a meaningful step in driving cash flow growth for Replenish while enhancing scalability and margins through the new pellet fertilizer business. #proactiveinvestors #replenishnutrientsholdingscorp #cse #erth #otc #vvivf #RegenerativeAgriculture #FertilizerInnovation #SustainableFarming #CropGrowth #NeilWiens #AgricultureNews #Farming2025 #ProactiveInvestors #SustainableSolutions #Agritech #FertilizerInnovation #MJAgSolutions #PelletFertilizer #ProbioticSoil #BeisekerFacility #CanadianAgriculture

    Tonix advances TNX-102 SL for depression after positive FDA meeting boosts development path

    Play Episode Listen Later Sep 24, 2025 4:21


    Tonix Pharmaceuticals Holdings CEO Dr. Seth Lederman shared with Steve Darling from Proactive to share a major milestone in the company's clinical development pipeline — the successful completion of a Type B Pre-Investigational New Drug meeting with the U.S. Food and Drug Administration regarding the potential development of TNX-102 SL for the treatment of major depressive disorder. Lederman said the FDA provided positive and constructive feedback, giving Tonix the confidence to move forward with plans to submit a supplemental new drug application to expand the therapeutic indications of TNX-102 SL. The company's approach is based on exploratory findings that suggest improving sleep quality may help alleviate depressive symptoms, offering a novel route to address a condition that affects millions and remains underserved by current therapies. Tonix believes that bedtime administration of TNX-102 SL could represent a first-in-class treatment by targeting the reduced quality and quantity of slow-wave sleep associated with depression. The medication is a tertiary amine tricyclic formulated for transmucosal absorption, allowing it to bypass first-pass hepatic metabolism. By contrast, currently approved tertiary amine tricyclic antidepressants are swallowed-pill formulations that are largely metabolized during first-pass to longer-lived secondary amine tricyclics. These older drugs typically require doses more than ten times higher than TNX-102 SL to be effective for MDD and are often associated with side effects such as weight gain, blood pressure changes, cognitive impairment, and sexual dysfunction. Tonix's development strategy aims to offer a more tolerable and targeted therapy for MDD by addressing sleep disruption — a known contributor to depressive symptoms — while minimizing the side effects seen with traditional treatments. #proactiveinvestors #tonixpharmaceuticalsholdingcorp #nasdaq #tnxp #Biotech #MPOXVaccine #Smallpox #TNX801 #VaccineDevelopment #ClinicalTrials #PharmaceuticalNews #MedicalResearch #WHO #GlobalHealth #InfectiousDiseases #Biopharma #ProactiveInvestors

    Nextech3D.AI unveils two-phase blockchain ticketing rollout, launching in Q4 2025

    Play Episode Listen Later Sep 24, 2025 6:34


    Nextech3D.AI CEO Evan Gappelberg joined Steve Darling from Proactive to share new details on the company's highly anticipated blockchain ticketing roadmap, which aims to unify ticketing, payments, digital identity, and AR/AI-powered navigation into one integrated platform. The rollout will follow a two-phase approach designed to balance accessibility and innovation. Phase 1 (Q4 2025 will see rhe launch of a custodial, walletless ticketing solution requiring no crypto wallet from users. Fans will be able to purchase tickets seamlessly using credit card, ACH, Apple Pay, or Google Pay. A secure custodial smart wallet will be created behind the scenes, eliminating Web3 friction while still delivering the benefits of on-chain technology to event organizers. This phase is designed for maximum accessibility, ease of adoption, and regulatory compliance. Phase 2 in early 2026 will feature the introduction of a native self-custody wallet option, giving users the flexibility to hold and manage their own blockchain-based tickets directly. This feature will appeal to more advanced Web3 users seeking greater autonomy and control. Gappelberg emphasized that this dual-track strategy positions Nextech3D.AI to participate in both the primary ticketing market and the lucrative secondary resale market, which is currently dominated by legacy incumbents. By combining the security of blockchain with a scalable revenue model, the company aims to disrupt the industry with a fan-friendly, organizer-focused platform that bridges mainstream accessibility with next-generation Web3 innovation. #nextech3d.al #otcqx #nexcf #cse #ntar #EvanGappelberg #ARway #AugmentedReality #SpatialMapping #IndoorNavigation #MapDynamics #EventTech #TradeShowSolutions #TechStocks #ARRevenueGrowth #3DTechnology #ProactiveInvestors #aws #amazonwebservice #tickets

    ReElement joins rare earth consortium, bolstering American Resources' role in U.S. defense supply

    Play Episode Listen Later Sep 24, 2025 3:00


    American Resources Corp CEO Mark Jensen joined Steve Darling to announce another key milestone for its portfolio company, ReElement Technologies Corporation. The company has officially been accepted as a member of the Consortium for Rare Earth Technologies (CREaTe), further solidifying its role as a strategic partner in strengthening the United States' domestic supply chain for critical minerals. Membership in CREaTe comes through ReElement's continued collaboration with Advanced Technology International (ATI), a leading facilitator of innovation partnerships across government and industry. This development follows a series of recent achievements for ReElement. The company was recently awarded $2 million under the U.S. Department of Defense's Industrial Base Analysis and Sustainment (IBAS) Program, designed to support initiatives that reinforce national security and industrial resilience. In addition, ReElement already holds membership in the Defense Industrial Base Consortium, positioning it as a recognized contributor to advancing secure, U.S.-based refining capabilities. Looking ahead, ReElement will work closely with ATI to pursue new procurement opportunities and expand its participation in defense-focused initiatives. Among these efforts is the submission of an application to join the Joint Directed Energy Consortium (JDEC), an exclusive, members-only program that fosters collaboration between government and private industry to accelerate the development and deployment of directed energy technologies for military use. As part of this initiative, ReElement intends to showcase its patented chromatography-based refining platform — a breakthrough technology that enables the onshoring of ultra-pure rare earth and critical mineral production. These materials are essential to advancing defense readiness, particularly in the development of next-generation technologies where supply chain security is paramount. Jensen emphasized that these milestones highlight ReElement's growing importance in the defense sector, as the company continues to provide innovative solutions that help ensure the United States maintains a reliable and secure supply of critical resources. #proactiveinvestors #americanresourcescorporation #nasdaq #arec #SustainableMining, #MineralRefining, #RecyclingInnovation, #CriticalMinerals, #RareEarthRecycling, #EVRecycling, #BatteryRecycling, #princialminerals #adamjohnson #RareEarths #EWasteRecycling #ReElement #CriticalMinerals #SustainableTech #MagnetRecycling #TechInnovation #GreenSupplyChain #ElectrifiedMaterials

    Powerhouse Energy CEO Paul Emmitt on FTU progress & client interest

    Play Episode Listen Later Sep 24, 2025 4:41


    Powerhouse Energy Group PLC (AIM:PHE) CEO Paul Emmitt talked with Proactive's Stephen Gunnion about the recent developments surrounding the company's Feedstock Testing Unit (FTU). Emmitt outlined the FTU's evolution over the past six months, highlighting its progress from commissioning through to a full testing regime involving various feedstocks, including Solid Recovered Fuel (SRF), Refuse Derived Fuel (RDF), and even chicken litter. The company has tailored specific feedstock compositions to match client needs, including Australia-based National Hydrogen, by recreating those compositions in the UK. According to Emmitt, “We've tested that through on a number of occasions with very, very consistent results and results better than we'd really expected.” He confirmed that the unit's improvements—especially modifications to the kiln's exit end—have led to higher hydrogen ratios and reduced residue carryover. These results have increased interest from international clients, with visits scheduled in the coming weeks. Emmitt also discussed the potential for new revenue streams, including the sale of residue and heat recovery applications such as district heating or pre-treatment of feedstock. He referenced research from SP Angel that incorporated the upgraded system's performance. With the FTU now validated and operating reliably, Emmitt said the focus is on securing commercial agreements: “The next steps are for the team and I to get basically a signature on the dotted line.” He acknowledged the patience of shareholders and expressed optimism heading into the final quarter of 2025, noting that while the year may have seemed quiet externally, substantial progress had been made behind the scenes. Visit Proactive's YouTube channel for more in-depth company updates, and don't forget to like this video, subscribe to the channel, and turn on notifications so you never miss a new release. #PowerhouseEnergy #FTU #HydrogenEnergy #CleanTech #SustainableEnergy #WasteToEnergy #PaulEmmitt #EnergyInnovation #GreenHydrogen #ProactiveInvestors

    European Green Transition CFO on H1 2025 results, Olserum Rare Earth & M&A plans

    Play Episode Listen Later Sep 24, 2025 5:12


    European Green Transition PLC (AIM:EGT) chief financial officer Jack Kelly talked with Proactive's Stephen Gunnion about the company's interim results for the first half of 2025. Kelly highlighted the progress made across the European Green Transition portfolio. He said the company successfully extended the key license at its Olserum Rare Earth project in Sweden until 2029, describing it as “a really strong positive position for the ongoing sale and partnership discussions.” The project has already demonstrated district-scale potential for rare earths. The company also secured extensions for its Pajala copper project licenses until 2028, and at no cost extended the option agreement for the Altan Carbon credit project in northwest Donegal by six months. Kelly pointed to growing activity in this area, noting recent investment pledges by major technology firms into peatland restoration in Ireland. On the corporate side, Cathal Friel, the largest shareholder, became executive chairman in June. Kelly explained that Friel is now leading the M&A strategy, with a focus on acquiring distressed, revenue-stage businesses in the green economy. He added: “We're in a very strong position from a cash perspective. We have 2.90 million as of 30th June and no debt, no committed cost.” For more interviews and updates, visit Proactive's YouTube channel. Don't forget to like this video, subscribe, and enable notifications to stay informed. #EuropeanGreenTransition #JackKelly #RareEarths #OlserumProject #CopperMining #CarbonCredits #SustainableInvestment #GreenEconomy #MergersAndAcquisitions #CleanEnergy

    EMV Capital CEO on acquisition of Destiny Pharma's lead asset, way forward

    Play Episode Listen Later Sep 23, 2025 6:33


    EMV Capital (AIM:EMVC) CEO Dr Ilian Iliev talked with Proactive's Stephen Gunnion about the company's acquisition of assets from liquidated Destiny Pharma and how the move aligns with its broader investment strategy. Iliev explained that EMV Capital applied its 'Venture Build Program' to identify, acquire, and rebuild value in the XF-73 drug asset, which had shown promise in phase 2 clinical trials but had stalled before entering phase three. He said, "We are able to look at opportunities such as the former Destiny Pharma and look at how we can identify, acquire and rebuild value in incredibly valuable assets." The structure of the deal includes both upfront payments and deferred milestone-based components, aligning long-term incentives with outcomes such as regulatory progress and licensing opportunities. EMV Capital is now preparing to restart the phase 3 trial for XF-73, focusing on capital efficiency and low cash burn strategies. Iliev also highlighted the global potential of XF-73 in tackling antimicrobial resistance and hospital-acquired infections, noting that the US market alone includes over two million patients who could benefit. He confirmed that commercialisation plans will prioritise the US while also targeting emerging markets through partnerships and joint ventures. The company's capital-efficient model, he emphasised, enables scaling of high-impact opportunities without excessive dilution to shareholders. For more updates, visit Proactive's YouTube channel. Don't forget to like the video, subscribe to the channel, and enable notifications to stay updated with our latest content. #EMVCapital #IlianIliev #ImpactInvesting #DestinyPharma #XF-73 #AntimicrobialResistance #HospitalInfections #PharmaInvestment #CapitalEfficiency #Phase3Trials #BiotechNews #HealthcareInnovation #EmergingMarkets

    Iofina PLC CEO: record revenues & IO#11 online

    Play Episode Listen Later Sep 23, 2025 6:17


    Iofina PLC (AIM:IOF, OTC:IOFNF) CEO Dr Tom Becker talked with Proactive's Stephen Gunnion about the company's record financial and operational performance during the first half of 2025, highlighting over $29 million in revenue and a 40% increase in profit, driven by expansion in iodine production. Becker explained that the company produced more than 305 metric tons of iodine during the period, supported by the launch of IO#11, Iofina's third plant in three years. “IO#11 is now fully online. So we have a range in the market between 400 and 440 tons. Confident in that range as we speak today,” he said, adding that this would likely represent another record for the business. With iodine prices remaining above $70 per kilogram, Becker said Iofina averaged over $74 per kilogram during the first half and expects prices to stay firm due to steady demand and limited excess supply. The company is already progressing toward IO#12, with construction expected to begin before year-end. Iofina is also advancing other projects aimed at boosting production and developing new value-added iodine products through its chemical division. Becker highlighted that the company ended the period with $6.4 million in cash and modest net debt, adding that IO#11 is already paid for and generating cash flow. He noted that a facility with its banking partner positions the company well to fund further plant construction. Looking ahead, Iofina plans to continue expanding while educating the market about its model of extracting iodine from oil and gas brine streams. “We're not a start-up, we have proven technology,” said Becker, who emphasised that consistent execution and outreach will be key to unlocking shareholder value. For more interviews like this, visit Proactive's YouTube channel. Don't forget to like the video, subscribe, and turn on notifications to stay up to date. #Iofina #IodineProduction #IO11 #TomBecker #OilAndGas #ChemicalIndustry #IodineMarket #SpecialtyChemicals #CapitalInvestment #ProactiveInvestors

    Digitalbox CEO on strong H1, surge in audience reach and future plans

    Play Episode Listen Later Sep 23, 2025 8:13


    Digitalbox PLC (AIM:DBOX) CEO James Carter talked with Proactive about the company's interim results, which showed strong growth in revenue, audience engagement, and on-platform performance. Carter said that Digitalbox saw a 15% increase in page impressions and a 30% increase in audience reach, reflecting higher engagement with its digital content. This translated into 12% revenue growth in a challenging advertising market. “We've grown our social footprint significantly, and on the back of that, we're managing to grow our reach,” he noted. A key contributor to this growth was on-platform monetisation, where revenues jumped from £160,000 in H1 2024 to £400,000 in H1 2025. The company has focused on growing its presence within the “walled gardens” of major tech platforms, increasing its social following from 3.5 million to nearly 30 million since listing. Carter also highlighted diversification as a core part of the strategy, with recent acquisitions including The Life Network from Video Chain and other bolt-ons. He said the company continues to seek future-proofing opportunities that reduce risk and support long-term growth. Despite macroeconomic uncertainty, Digitalbox remains optimistic about building momentum into 2026 with new product launches and further acquisitions under consideration. For more interviews like this, visit Proactive's YouTube channel. Don't forget to like this video, subscribe, and enable notifications for future updates. #Digitalbox #MediaStocks #OnlinePublishing #SocialMediaGrowth #DigitalAdvertising #InvestorUpdate #H1Results #JamesCarter #ProactiveInvestors #AIMMarket #DigitalMedia

    hVIVO CEO Mo Khan on H1 2025 results & outlook

    Play Episode Listen Later Sep 23, 2025 7:28


    hVIVO PLC chief executive Yamin ‘Mo' Khan talked with Proactive's Stephen Gunnion about the company's unaudited results for the first half of 2025 and its outlook for the remainder of the year. Khan explained that revenue for the period came in at just over £24 million, supported by a diversified mix of services, therapeutics, and clients. He added that EBITDA of around £3 million was “helped by the postponement and cancellation fees that we recognised in the first half of this year, together with some of the operational efficiencies that we have already put in place and disciplined cost management.” Cash at 30 June 2025 stood at just over £23 million, while the weighted contracted order book was about £40 million. He noted that the broader CRO industry has faced macroeconomic and sector headwinds, particularly in the vaccine field, which has led to postponements, cancellations, and longer sales cycles. Despite this, Khan said he believes human challenge trials remain highly relevant and could see stronger adoption as drugmakers look to develop medicines faster and at lower cost. The integration of CRS and Cryo Store has progressed well, delivering cross-selling opportunities and annualised savings. Looking ahead, hVIVO expects to deliver about £47 million in revenue for 2025, with a small single-digit EBITDA loss, and aims to return to growth in 2026. For more interviews and updates, visit Proactive's YouTube channel. Don't forget to like this video, subscribe to the channel, and enable notifications for future content. #hVIVO #ClinicalTrials #HumanChallengeTrials #CRO #BiotechNews #DrugDevelopment #ClinicalResearch #LifeSciences #HealthcareInnovation #ProactiveInvestors

    Tonix gains global rights to TNX-4800, developing one-dose seasonal protection for Lyme disease

    Play Episode Listen Later Sep 22, 2025 4:07


    Tonix Pharmaceuticals Holdings CEO Dr. Seth Lederman shared with Steve Darling from Proactive that the company has secured an exclusive worldwide in-licensing agreement for TNX-4800, a groundbreaking investigational therapy designed to provide seasonal protection against Lyme disease. The treatment is intended as a single subcutaneous dose administered in the spring to offer protection throughout the entire tick season, lasting into the fall. Originally developed by researchers at UMass Chan Medical School, TNX-4800 is being licensed to Tonix to advance its development and commercialization. This strategic acquisition represents a significant milestone in the company's mission to expand its infectious disease pipeline with innovative solutions. Lederman emphasized that there are currently no FDA-approved vaccines or prophylactic treatments available to prevent Lyme disease, which remains the most prevalent vector-borne illness in the United States. Reported cases are rising annually, underscoring the urgent need for effective preventive measures. Tonix believes TNX-4800 offers a potentially transformative approach. The therapy is designed to provide protective immunity within just two days of administration and to maintain its protective effect through the full tick season. Unlike conventional vaccine approaches, TNX-4800 uses a novel mechanism of action: it blocks the maturation of Borrelia burgdorferi—the bacteria that cause Lyme disease—in the midgut of infected deer ticks. By delivering a well-characterized antibody directly, TNX-4800 has demonstrated the ability to block the transmission of major Borrelia genospecies from ticks to animals in preclinical studies. This unique, single-dose seasonal model could simplify Lyme disease prevention and deliver broad public health benefits, positioning Tonix Pharmaceuticals as a leader in next-generation infectious disease prophylaxis. #proactiveinvestors #tonixpharmaceuticalsholdingcorp #nasdaq #tnxp #Biotech #MPOXVaccine #Smallpox #TNX801 #VaccineDevelopment #ClinicalTrials #PharmaceuticalNews #MedicalResearch #WHO #GlobalHealth #InfectiousDiseases #Biopharma #ProactiveInvestors #LymeDisease #TNX4800 #BiotechNews

    Oriole Resources extends gold system at Mbe with final drill results, eyes maiden gold resource

    Play Episode Listen Later Sep 22, 2025 4:04


    Oriole Resources PLC (AIM:ORR) executive director Claire Bay talked with Proactive's Stephen Gunnion about the final drilling results from the company's maiden programme at the Mbe Project, specifically at the MB01 South target. Bay explained that the drilling confirmed further extensions of the mineralised system, adding 100 metres to the south and 100 metres to the west. She highlighted that one of the western holes delivered almost 30 metres at 0.8 grams per tonne of gold, including 14 metres at 1.4 grams per tonne. “Importantly, almost all the results from that hole fall outside of the current exploration target,” she said, noting the scale of opportunity across the licence package. The company had previously set an exploration target of between 0.82 million and 1.34 million ounces of gold for MB01 as a whole, with MB01 South accounting for about 60% of that. According to Bay, the results will now be passed to independent consultants at Forge International, who are working to convert exploration targets into a maiden mineral resource estimate for the MB01 South prospect. Bay added that the system remains open in all directions and pointed to additional upside potential at MB01 North, located nearby but not yet drilled. For more videos, visit Proactive's YouTube channel. Don't forget to give this video a like, subscribe to the channel, and enable notifications so you never miss an update. #OrioleResources #GoldExploration #MbeProject #DrillingResults #GoldInvesting #MiningUpdates #ResourceEstimate #ExplorationPotential

    Ilika CEO talks PRIMED roadmap & Jaguar Land Rover input

    Play Episode Listen Later Sep 22, 2025 3:13


    Ilika PLC (AIM:IKA, OTCQX:ILIKF) CEO Graeme Purdy talked with Proactive's Stephen Gunnion about the new PRIMED programme and its role in advancing the company's solid-state battery development. Purdy explained that the PRIMED programme provides vital support for delivering one of the key milestones in the Goliath roadmap — the production of 50Ah A-Sample batteries. “The PRIMED program is a fantastic piece of support … to deliver one of the key milestones of the Goliath roadmap,” he said. Achieving this requires large-scale production equipment, and Ilika is collaborating with the UK Battery Industrialisation Centre (UK BIC) to make this possible. He added that Ilika is also working with HSSMI to create a production-scale model. This will deliver insights into cost modelling, operational processes, and provide a business case review for Gigafactory-scale manufacturing. One of the most significant aspects of the collaboration, according to Purdy, is the expert industrial input being provided by Jaguar Land Rover and Professor Paul Shearing of Oxford University. Their role on the steering committee will help guide design and process decisions as the company moves towards its P2 release. Looking ahead, Purdy noted that investors can expect announcements on technical progress, prototype testing, and possible new commercial collaborations over the next 12 months. For more updates, visit Proactive's YouTube channel. Don't forget to like this video, subscribe, and enable notifications for future content. #IlikaPLC #SolidStateBatteries #BatteryTech #EnergyStorage #PRIMEDProgramme #JaguarLandRover #OxfordUniversity #EVBatteries #CleanEnergy #ProactiveInvestors

    Immunic talks vidofludimus calcium & patent milestone at ECTRIMS 2025

    Play Episode Listen Later Sep 22, 2025 7:29


    Immunic Inc (NASDAQ:IMUX) president and chief operating officer Jason Tardio talked with Proactive's Stephen Gunnion about the company's presence at the 41st Congress of ECTRIMS in Barcelona this week and the progress of its lead multiple sclerosis candidate, vidofludimus calcium. Tardio explained that Immunic is showcasing one oral and four poster presentations, including late-breaking data from the Phase 2 CALLIPER study in progressive multiple sclerosis. He said, “We showed very strong signals for reduction in confirmed disability worsening … and of course, the medicine is also and continues to be very safe and well tolerated in this population.” The CALLIPER trial assessed vidofludimus calcium in nearly 475 patients with both non-active secondary progressive MS and primary progressive MS. Tardio highlighted that the drug candidate showed promising effects on disability progression and MRI outcomes, addressing a high unmet need in this patient group. Immunic was also granted its fifth MS-directed US patent for vidofludimus calcium, covering multiple dosage strengths and applications in progressive MS and providing intellectual property protection until 2041. According to Tardio, this further strengthens the company's multilayered patent portfolio for vidofludimus calcium. Looking ahead, Immunic plans end-of-Phase 2 discussions with both the FDA and EMA before moving toward a potential Phase 3 program in progressive MS. Top-line data from the ENSURE-1 and -2 studies in relapsing MS are expected by the end of 2026. For more insights from Immunic and updates on the biotechnology sector, visit Proactive's YouTube channel. Don't forget to give the video a like, subscribe to the channel, and enable notifications so you never miss future content. #ImmunicInc #MultipleSclerosis #VidofludimusCalcium #ECTRIMS2025 #BiotechNews #ClinicalTrials #MSResearch #PharmaInnovation #DrugDevelopment #PatentNews

    Valereum CEO Gary Cottle on revenues, partnerships & pipeline

    Play Episode Listen Later Sep 22, 2025 6:29


    Valereum PLC (AQSE:VLRM) CEO Gary Cottle talked with Proactive's Stephen Gunnion about the company's progress in building a world-class ecosystem for tokenisation and digital assets. Cottle explained that Valereum is now moving beyond development and into delivery. He said the companies within Valereum's ecosystem, including DigiShares and Fideum, are “already quite mature in a very immature market” and are positioned as potential category leaders. He highlighted that Valereum has integrated DigiShares' infrastructure to replace its wallet solution, which is set to be adopted across regulated Valereum markets. The CEO also revealed that the company is expanding its reach through collaborations, including an upcoming partnership with Agentic AI. Cottle said these businesses are “all making good headway, and they're making quick ground in their markets.” When discussing asset focus, he pointed to opportunities in football clubs, real estate, metals inventory, and gold mines — assets he described as ripe for tokenization due to their illiquidity. Valereum has already soft-launched its regulated markets platform and is growing a pipeline of transactions, with several already announced. Looking ahead, Cottle stressed that revenues and growth remain the company's most important milestones. He noted that most of Valereum's current focus is on business development, with partners such as DigiShares and Fideum also pursuing new market opportunities. For more interviews with company leaders, visit Proactive's YouTube channel. Don't forget to like this video, subscribe, and turn on notifications to stay updated. #Valereum #Tokenization #DigitalAssets #GaryCottle #RWA #BlockchainFinance #DigiShares #Fideum #FootballFinance #RealEstateTokenization #ProactiveInvestors

    Pan Global CEO Tim Moody on new gold discovery at Cármene plus update on Escacena project

    Play Episode Listen Later Sep 22, 2025 5:07


    Pan Global Resources Inc (TSX-V:PGZ, OTCQB:PGNRF) CEO Tim Moody talked with Proactive about the company's exploration progress in Spain, highlighting both copper and gold discoveries. Moody explained that Pan Global is a Canadian-listed company focused on copper and gold exploration, with projects centered on the Iberian Pyrite Belt. He noted that the flagship Escacena project includes the La Romana copper discovery, with a maiden mineral resource estimate expected before the end of the year. “It de-risked the investment for new investors because we have something of value that's likely to be a mine and could be a mine in short term,” Moody said. At the Providencia target within the Cármenes project, drilling has confirmed high grades of copper, nickel, and cobalt, alongside a new gold discovery. Moody highlighted that intersections include 36 meters of three grams per tonne gold, a strong near-surface result that the company plans to follow up with further drilling. He also emphasized that copper is on Europe's critical materials list, which positions the company to benefit from rising demand linked to electrification and the energy transition. Additional drill results, the forthcoming mineral resource estimate, and continued exploration at the gold discovery are the near-term milestones investors should expect. For more updates from Pan Global Resources and other companies, visit Proactive's YouTube channel. Don't forget to like this video, subscribe to the channel, and enable notifications for future content. #PanGlobalResources #CopperExploration #GoldDiscovery #SpainMining #CriticalMetals #EnergyTransition #MiningInvesting #Copper #Gold

    Hercules CEO and CFO on £6.5m UK water contracts and future prospects

    Play Episode Listen Later Sep 22, 2025 3:07


    Hercules PLC (LSE:HERC) CEO Brusk Korkmaz and CFO Paul Wheatcroft talked with Proactive's Stephen Gunnion about the company's newly secured contracts in the UK water sector worth approximately £6.5 million. Korkmaz said the wins strengthen the company's position as a trusted partner: “With our experience and growing presence nationwide, more clients are trusting Hercules to deliver vital infrastructure projects.” The new contracts position Hercules to contribute to essential improvements in water and wastewater services across the UK. Wheatcroft highlighted that Hercules already works with key regional water companies including Anglian Water, Thames Water, Southern Water, Severn Trent Water, Wessex Water, United Utilities, Welsh Water, and Yorkshire Water. Additionally, the company has established new agreements with Galliford Try, Costain, Tilbury Douglas, NWH Treatment, Glanua, and Thames Water. He explained that the contracts come at a time when the UK water sector is seeing record investment, following Ofwat regulatory reviews. Over £104 billion is expected to be invested during the current AMP8 period, with a focus on upgrading aging infrastructure and increasing environmental resilience. Both executives expressed confidence in Hercules' ability to deliver as demand grows. Korkmaz reiterated the company's commitment: “We are set to play an important role in improving water and wastewater services across the country.” For more videos, visit Proactive's YouTube channel. Don't forget to like the video, subscribe to the channel, and turn on notifications for future updates. #HerculesPLC #WaterInfrastructure #UKConstruction #AMP8 #WaterUtilities #InfrastructureInvestment #ProactiveInvestors #BruskKorkmaz #PaulWheatcroft #UKWaterSector #ThamesWater #ConstructionNews

    Foresight Solar Fund's Ross Driver on H1 2025 results, buyback and growth pipeline

    Play Episode Listen Later Sep 22, 2025 3:59


    Foresight Solar Fund Ltd (LSE:FSFL) fund manager Ross Driver talked with Proactive's Stephen Gunnion about the company's results for the six months to 30 June 2025. Driver said the performance during the first half of the year highlighted “the quality of the operational portfolio and the expertise of the team” and reinforced a resilient cash position. He noted that the fund's share buyback programme has been a consistent source of value for shareholders since 2023 and that the board recently allocated a further £10.00 million to extend the initiative. Discussing the fund's capital allocation priorities, Driver explained that cash is being balanced between shareholder returns, debt reduction, and reinvestment in development opportunities. He highlighted progress in Spain, where the fund has secured capacity for battery storage projects and expects one of its solar developments to reach ready-to-build status soon. On dividends, Driver confirmed that Foresight Solar Fund has raised payments every year since 2013, supported by wholesale power prices and its proactive hedging approach. He reiterated the company's 1.3x dividend cover target for 2025. Looking ahead, Driver said the fund remains focused on narrowing the discount between its share price and NAV, while also advancing divestments to free up capital for shareholders. For more interviews and company updates, visit Proactive's YouTube channel. Don't forget to like this video, subscribe, and enable notifications to stay up to date with future content. #ForesightSolarFund #RenewableEnergy #SolarPower #DividendInvesting #BatteryStorage #CleanEnergy #InvestmentFunds #EnergyTransition #ProactiveInvestors

    Trust Stamp extends Fortune 500 deal to 2031 with new fee structure

    Play Episode Listen Later Sep 22, 2025 3:34


    Trust Stamp President Andrew Gowasack joined Steve Darling from Proactive to announce a major milestones: an extended agreement with a key Fortune 500 financial services customer The company revealed that it has amended its long-standing Software and Licensing Agreements, originally signed in 2016, extending the relationship through 2031. The new terms introduce a revised fee structure that scales with usage of Trust Stamp's advanced identity authentication solutions, including guaranteed minimum monthly fees and annual inflation-linked adjustments. This structure is designed to provide both revenue stability and predictable long-term growth as the client continues to expand its deployment of Trust Stamp's technology. Gowasack told Proactive that based on the updated minimum commitments, the agreement is expected to generate gross revenue exceeding $12.7 million over the balance of the contract. The client—described as a Fortune 500 financial services leader and one of the largest issuers of private-label and co-branded credit cards in the United States—has been a critical partner for Trust Stamp for nearly a decade. #proactiveinvestors #truststamp #nasdaq #idai #IdentityTech #DigitalIdentity #Fintech #GhanaID #SouthKoreaStartup #AsiaExpansion #KStartupChallenge #FinancialServices #Biometrics #TechExpansion #ProactiveInvestors #AndrewGowasack

    Abacus Global Management joins Russell 2000® and 3000® indexes, boosting institutional visibility

    Play Episode Listen Later Sep 22, 2025 3:33


    Abacus Global Management CEO Jay Jackson joined Steve Darling from Proactive to announce a significant milestone for the company: effective with the opening of U.S. equity markets on September 22, 2025, Abacus Global Management has been officially added to both the Russell 2000® and the Russell 3000® Indexes as part of the annual reconstitution of the 2025 Russell indexes. Jackson explained that inclusion in the Russell 2000® automatically brings the company into the broader Russell 3000® Index, as well as into the appropriate growth and value style indexes. He described this achievement as a pivotal moment in Abacus Global's trajectory, providing enhanced visibility and credibility among institutional investors while underscoring the company's ability to deliver shareholder value. The Russell indexes, administered by FTSE Russell, are some of the most widely tracked benchmarks in global finance. They serve as the basis for both index funds and active investment strategies, with approximately $10.6 trillion in assets benchmarked to Russell's U.S. indexes. Membership offers Abacus Global increased exposure to a broad base of institutional investors and portfolio managers that rely on these indexes to guide capital allocation. Jackson noted that inclusion in the indexes reflects the company's growth and performance to date and positions Abacus Global to further broaden its shareholder base, strengthen liquidity, and continue building long-term value for investors. #proactiveinvestors #abacusglobalmanagement #nasdaq #abl #JayJackson #EarningsBeat #FinancialGrowth #LifeSettlements #InvestorDemand #CashFlow #AssetManagement #2025Outlook #ProactiveInvestors

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