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Welcome to the Part Time Pilot Audio Ground School VIP Podcast! This podcast takes our free podcast to a whole new level by providing students with every single lesson included in the Part Time Pilot Private Pilot & IFR Ground Schools without a single Ad! On top of that, VIP podcast students get BONUS episodes like Mock Checkrides, Checkride Prep, Expert Interviews and more! The #1 reason student pilots never end up becoming a private pilot is NOT due to money. The real reason is actually deeper than that. Yes, flight training is expensive. But every student pilot knows this and budgets for it when they decide to do it. The actual #1 reason a student pilot fails is because they do not have a good, fundamental understanding of the private pilot knowledge they are meant to learn in ground school. You see when a student does not have a good grasp of this knowledge they get to a point in their flight training where their mind just can't keep up. They start making mistakes and having to redo lessons. And THAT is when it starts getting too expensive. This audio ground school is meant for the modern day student pilot... aka the part time student pilot. Let's face it, the majority of us have full time responsibilities on top of flight training. Whether it is a job, kids, family, school, etc. we all keep ourselves busy with the things that are important to us. And with today's economy we have to maintain that job just to pay for the training. The modern day student pilot is busy, on the go and always trying to find time throughout his or her day to stay up on their studies. The audio ground school allows them to consume high quality content while walking, running, working out, sitting in traffic, traveling, or even just a break from the boring FAR/AIM or ground school lecture. Did I meant high quality content? The audio ground school is taken straight out of the 5-star rated Part Time Pilot Online Ground School that has had over 2000 students take and pass their Private Pilot & IFR exams with only 2 total students failing the written. That's a 99.9% success rate! And the 2 that failed? We refunded their cost of ground school and helped them pass on their second attempt. We do this by keeping ground school engaging, fun, light and consumable. We have written lessons, videos, audio lessons, live video lessons, community chats, quizzes, practice tests, flash cards, study guides, eBooks and much more. Part Time Pilot was created to be a breath of fresh air for student pilots. To be that flight training provider that looks out for them and their needs. So that is just what we are doing with this podcast. IFR Section 2 - Lesson 15: In this lesson, we review Flying the Glideslope & Localizer we care about as IFR pilots. We talk about what they are, what they are used for and why we use them. This is a key concept you should have learned in private pilot but if not, we will review it for you hear as it sets up the following lessons on IFR instrumentation. Links mentioned in the episode: Private Pilot Online Ground School: PPL Ground School - Part Time Pilot Checkride Prep: PPL Checkride Prep - Part Time Pilot Ultimate Private Pilot Test Prep Book: Book on Amazon IFR Online Ground School: IFR Ground School – Part Time Pilot PPL study group: https://www.facebook.com/groups/parttimepilot IFR study group: https://www.facebook.com/groups/parttimepilotifr/ Private Pilot Flash Card book on Amazon: https://amzn.to/3NKd0bu Flying Glideslope & Localizer Video: https://youtu.be/oVW7C_2x34U Recommended Products & Discounts: https://parttimepilot.com/recommended-products-for-student-pilots/
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David Crislip has had quite the life! The man studied Japanese at Ohio University before moving to Japan to become an English Teacher there before ending up at Capcom Japan where he did localization for over 10+ years. #capcom #residentevil #streetfighter SOCIAL MEDIA TWITTER - @DavidCrislip INSTAGRAM - @davidcrislipTIMESTAMPS00:00 - Intro01:20 - What Prompted David Wanted To Learn Japanese02:50 - How Long It Takes To Be Fluent In Japanese/Being An English Teacher In Japan05:20 - Early Days Of Localisation Capcom Japan06:20 - Why Direct Translation Doesn't Work08:16 - Japanese Is A Very Dense Language09:00 - How Localisation Has Changed From The Old Days11:20 - Playing Games In Different Dubs12:30 - Ghost Of Tsushima Is An Example Of A Western Game That Got Japanese Correct13:20 - Lip Flapping In The Old Days Vs Now/David Is Glad He Doesn't Have To Localise AAA Games These Days14:10 - Immigration Officers Geeking Out Over David Working At Capcom16:42 - David's Favourite Capcom Games19:45 - Resident Evil 4 Remake20:30 - Capcom Were Aware Well Making Resident Evil 4 That It Would Be Special22:20 - Capcom's Renaissance Is Very Gratifying24:00 - David's Favourite Capcom Game To Work On25:45 - Capcom Have Westernised Games With Japanese Flavour26:15 - How David Ended Up Voicing Winston Payne/Recording Lines28:10 - Difference Between Translating Text Vs Dialog29:40 - The Misunderstanding Gamers Have Of Localisation31:00 - How Long It Took David To Adapt To Japanese Culture35:10 - Its Very Difficult To Get A Job At Capcom/Applying For Jobs In Japan36:40 - Japanese Are Aware Of Western Culture/Language Shapes Your Behaviour 38:15 - David Doesn't Translate In His Head Whether Its Japanese Or English39:15 - Why Lay Offs Don't Happen Often In Japan42:00 - Japanese & Western Games Are Both On Equal Footing Now43:00 - Consoles David Plays/David Shows Off His Game Collection44:15 - David's Favourite Game Of All Time/David Plays Games Most Days46:09 - David's Advice For Getting Into The Video Game Industry In Japan48:07 - Where To Follow David Crislip
The dub for 'Lovely Complex' has come under fire due to one of its localizers, a YouTuber named JelloApocalypse, loudly and proudly saying the series sucked and he was working to "improve" the dub by "fixing" what he thought was political incorrectness. And apparently, Discotek has fired him for it. Then we talk about the infamous dub for 'Ghost Stories.' ➡️ Tip Jar and Fan Support: http://ClownfishSupport.com ➡️ Official Merch Store: http://ShopClownfish.com ➡️ Official Website: http://ClownfishTV.com ➡️ Audio Edition: https://open.spotify.com/show/6qJc5C6OkQkaZnGCeuVOD1 ➡️ Gaming News: https://open.spotify.com/show/0A7VIqE3r5MQkFgL9nifNc Additional Context: The anime landscape is no stranger to controversy, especially when it comes to the dubbing and localization of beloved series for Western audiences. The latest whirlwind to hit the community centers around "Lovely Complex," a rom-com anime that has charmed viewers with its quirky take on the dynamics of love and friendship. However, the series' English dub adaptation has ignited a firestorm, thanks to the involvement and subsequent comments of a localizer known on YouTube as JelloApocalypse. JelloApocalypse, a content creator with a significant following, took to the digital soapbox to express his dissatisfaction with "Lovely Complex," going as far as to claim the series "sucked" and that he was on a mission to "improve" the dub by "fixing" elements he deemed politically incorrect. This bold, if not brazen, approach to localization—where subjective interpretation overshadows faithful adaptation—has sparked a heated debate within the anime community. Fans and critics alike are wrestling with questions about the boundaries of localization, the integrity of original content, and the responsibilities of those tasked with adapting cultural products for new audiences. Discotek Media, the company behind the English dub of "Lovely Complex," found itself in the eye of the storm, leading to the reported firing of JelloApocalypse. This move reflects the delicate balance companies must strike in maintaining the authenticity of source material while navigating the sensitivities of diverse audiences. It also underscores the potential consequences for localizers who prioritize personal agendas over professional integrity. The controversy surrounding "Lovely Complex" inevitably draws parallels to the infamous dub of "Ghost Stories." In the case of "Ghost Stories," the localizers were given carte blanche to alter the script as long as they kept the basic plot intact, resulting in a dub that was wildly different in tone and content, filled with ad-libbed humor, pop culture references, and politically incorrect jokes. While some hailed it as a comedic masterpiece and a cult classic, others criticized it for straying too far from the original. The situation with "Lovely Complex" raises important questions about the role of localization in the global spread of anime. It challenges the industry to find a balance between making content accessible and relatable to international audiences without sacrificing the essence that made these works resonate with their original viewers. As the dust settles on this particular controversy, the conversation it has sparked about cultural respect, artistic integrity, and the evolving nature of localization in the anime industry is likely to continue resonating for some time. About Us: Clownfish TV is an independent, opinionated news and commentary channel that covers Entertainment and Tech from a consumer's point of view. We talk about Gaming, Comics, Anime, TV, Movies, Animation and more. Hosted by Kneon and Geeky Sparkles. Disclaimer: This series is produced by Clownfish Studios and WebReef Media, and is part of ClownfishTV.com. Opinions expressed by our contributors do not necessarily reflect the views of our guests, affiliates, sponsors, or advertisers. ClownfishTV.com is an unofficial news source and has no connection to any company that we may c
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Western anime localizers strike again! Now an apparently unpaid (?) activist turned localizer is bragging about the changes they got away with for Discotek's release of Lovely Complex. And they also CONFIRM what anime fans have long suspected -- these changes to the originals are seemingly ENCOURAGED but the publishers don't want you to talk about it. But he does... ➡️ Tip Jar and Fan Support: http://ClownfishSupport.com ➡️ Official Merch Store: http://ShopClownfish.com ➡️ Official Website: http://ClownfishTV.com ➡️ Audio Edition: https://open.spotify.com/show/6qJc5C6OkQkaZnGCeuVOD1 ➡️ Gaming News: https://open.spotify.com/show/0A7VIqE3r5MQkFgL9nifNc Additional Context: As a keen observer of the evolving landscape of anime localization, it's impossible not to notice the latest buzz stirring the pot of controversy. The discourse centers around Discotek's release of "Lovely Complex," a beloved romantic comedy anime that has found itself at the heart of a fresh debate on the practice of localization versus the integrity of the original content. The story, as it unfolds, involves an activist turned localizer—who, by the way, claims not to have been compensated for their efforts—boasting about alterations made to the anime's English version. This revelation isn't just a drop in the ocean; it's a tsunami that confirms the suspicions of many anime fans: that these modifications to the source material are not just happening but are seemingly encouraged by publishers, who, however, prefer to keep such directives under wraps. Localization, for the uninitiated, is the process of adapting content for a different cultural context, which may involve changes to dialogue, cultural references, and sometimes even plot points to make the material more accessible to the target audience. This practice has long been a topic of contention within anime communities, with purists advocating for "faithful" translations that stick closely to the original Japanese script and others arguing for the necessity of adaptation to bridge cultural and linguistic gaps. The "Lovely Complex" situation sheds light on the underbelly of the localization process, revealing a more complicated narrative. The localizer's admission—especially the part about being seemingly unpaid—raises questions about the working conditions and transparency within the anime localization industry. Moreover, the claim that publishers encourage changes to the original content, yet discourage public discussion on the matter, points to a potentially systemic issue of editorial control and the dilution of artistic integrity in the name of accessibility. This incident isn't just about "Lovely Complex" or Discotek; it's emblematic of a broader debate within the anime community and the entertainment industry at large. It touches upon the delicate balance between preserving the authenticity of original works and making them relatable to a global audience. Where should the line be drawn? And who gets to draw it? As this story unfolds, it invites a plethora of questions about the ethics of localization, the respect for original creators, and the rights of the workers involved in the process. The anime community is no stranger to passionate debates, and this latest development is sure to fuel discussions on forums, social media, and beyond. In the end, this controversy is a reminder of the complexities involved in bringing beloved stories from one culture to another. It's a call to action for more transparency, fair labor practices, and perhaps a reassessment of what localization should entail in an increasingly globalized world. Whether this will lead to changes in how anime is localized remains to be seen, but one thing is clear: the conversation is far from over. About Us: Clownfish TV is an independent, opinionated news and commentary channel that covers Entertainment and Tech from a consumer's point of view. We talk about Gaming, Comics, Anime, TV, Movies, Animation and more. Hosted by Kne
Subscriber-only episodeClick the link to subscribe and listen now. The full length lesson for: Localizer Back Course Approach. If you already have a premium membership on wifiCFI then YOU SHOULD NOT SUBSCRIBE to this podcast membership as you are already receiving all exclusive content for free! It is included in your study courses.
Subscriber-only episodeClick the link to subscribe and listen now. The full length lesson for: Localizer Back Course Approach. If you already have a premium membership on wifiCFI then YOU SHOULD NOT SUBSCRIBE to this podcast membership as you are already receiving all exclusive content for free! It is included in your study courses.
Subscriber-only episodeClick the link to subscribe and listen now. The full length lesson for: Localizer Approach. If you already have a premium membership on wifiCFI then YOU SHOULD NOT SUBSCRIBE to this podcast membership as you are already receiving all exclusive content for free! It is included in your study courses.
Click the link to subscribe and listen now. The full length lesson for: Localizer Approach. If you already have a premium membership on wifiCFI then YOU SHOULD NOT SUBSCRIBE to this podcast membership as you are already receiving all exclusive content for free! It is included in your study courses.Support the show
Join Drs Kevin Kalinsky and Jennifer Litton as they discuss hereditary breast cancer, genetic testing, and therapeutic implications. Relevant disclosures can be found with the episode show notes on Medscape (https://www.medscape.com/viewarticle/991258). The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals. Resources A Review of Triple-negative Breast Cancer https://www.medscape.com/viewarticle/727195_4 PARP and PARG Inhibitors in Cancer Treatment https://pubmed.ncbi.nlm.nih.gov/32029455/ BRCA1 and BRCA2 Mutations https://www.ncbi.nlm.nih.gov/books/NBK470239/ Iniparib Plus Chemotherapy in Metastatic Triple-negative Breast Cancer https://pubmed.ncbi.nlm.nih.gov/21208101/ Neoadjuvant Talazoparib for Patients With Operable Breast Cancer With a Germline BRCA Pathogenic Variant https://pubmed.ncbi.nlm.nih.gov/31461380/ ER/PgR Testing in Breast Cancer Clinical Practice Guidelines (ASCO/CAP, 2020) https://reference.medscape.com/viewarticle/924542 Pathological Complete Response in Neoadjuvant Treatment of High-risk Early-stage Breast Cancer: Use as an Endpoint to Support Accelerated Approval Guidance for Industry https://www.fda.gov/media/83507/download Adjuvant Olaparib for Patients With BRCA1- or BRCA2-mutated Breast Cancer https://pubmed.ncbi.nlm.nih.gov/34081848/ PALB2 Partner and Localizer of BRCA2 https://www.ncbi.nlm.nih.gov/gene/79728 Pre-specified Event Driven Analysis of Overall Survival (OS) in the OlympiA Phase III Trial of Adjuvant Olaparib (OL) in Germline BRCA1/2 Mutation (gBRCAm) Associated Breast Cancer https://oncologypro.esmo.org/meeting-resources/esmo-virtual-plenary-resources/olympia-phase-iii-pre-specified-event-driven-analysis-of-overall-survival-of-olaparib-in-gbrcam-breast-cancer Pembrolizumab for Early Triple-negative Breast Cancer https://pubmed.ncbi.nlm.nih.gov/32101663/ Olaparib for Metastatic Breast Cancer in Patients With a Germline BRCA Mutation https://pubmed.ncbi.nlm.nih.gov/28578601/ Talazoparib in Patients With Advanced Breast Cancer and a Germline BRCA Mutation https://pubmed.ncbi.nlm.nih.gov/30110579/ Veliparib With Temozolomide or Carboplatin/Paclitaxel Versus Placebo With Carboplatin/Paclitaxel in Patients With BRCA1/2 Locally Recurrent/Metastatic Breast Cancer: Randomized Phase II Study https://pubmed.ncbi.nlm.nih.gov/29045554/ RAD51 Recombinase https://www.ncbi.nlm.nih.gov/gene/5888 The ATM Gene in Breast Cancer: Its Relevance in Clinical Practice https://pubmed.ncbi.nlm.nih.gov/34068084/ Genetics of Breast and Gynecologic Cancers (PDQ®)–Health Professional Version https://www.cancer.gov/types/breast/hp/breast-ovarian-genetics-pdq Tissue-agnostic Drug Approvals: How Does This Apply to Patients With Breast Cancer? https://pubmed.ncbi.nlm.nih.gov/34518552/
ASCO: You're listening to a podcast from Cancer.Net. This cancer information website is produced by the American Society of Clinical Oncology, known as ASCO, the voice of the world's oncology professionals. The purpose of this podcast is to educate and to inform. This is not a substitute for professional medical care and is not intended for use in the diagnosis or treatment of individual conditions. Guests on this podcast express their own opinions, experience, and conclusions. Guests' statements on this podcast do not express the opinions of ASCO. The mention of any product, service, organization, activity, or therapy should not be construed as an ASCO endorsement. Cancer research discussed in this podcast is ongoing, so data described here may change as research progresses. In this podcast, Dr. Allison Kurian and genetic counselor Kristen Mahoney Shannon talk about what people should know about genetic testing and hereditary breast cancer, including what to expect when meeting with a genetic counselor, ways to reduce your risk of developing cancer, and talking about genetic test results with family. Dr. Kurian is a Professor of Medicine and of Epidemiology and Population Health at Stanford University School of Medicine, and Director of the Stanford Women's Clinical Cancer Genetics Program. She is also the 2023 Cancer.Net Specialty Editor for Breast Cancer. Ms. Shannon is a senior genetic counselor and Director of the Cancer Center Genetics Program and Director of Genetic Counseling for the Massachusetts General Hospital Department of Medicine. She is also a 2023 Cancer.Net Advisory Panelist. View disclosures for Dr. Kurian and Ms. Shannon at Cancer.Net. Dr. Allison Kurian: I'm Allison Kurian. I am a professor of medicine, oncology, and epidemiology and population health at Stanford University. And I am speaking today with my colleague, Kristen Shannon, who will introduce herself. Kristen Shannon: Hi, it's great to be here. My name is Kristen Shannon. I am a genetic counselor and the director of cancer genetics at Massachusetts General Hospital in Boston. And I have no financial relevant disclosures to report. Dr. Allison Kurian: Thank you, and I have no relevant financial disclosures either. Very good. So today we will be talking about breast cancer and inherited risk and genetic testing. And let me start by providing a definition of a genetic or hereditary condition. So the way we think about this is something that has a high risk for developing a disease, not a certainty, but a high risk, and runs in families, generally because of a genetic finding that we can identify. And that typically is identified through sequencing, testing of blood or saliva samples, and typically allows us to find a change that we know is clearly associated with disease. A good example for breast cancer are the genes BRCA1 and BRCA2, which some may have heard of, and we will talk about further. So that is just an example, and we will get into more of the details of this as we go on. But I think the point is something that runs in families often is seen with the trait, so for BRCA1 or BRCA2, that would be breast cancer or ovarian cancer, affecting people in every generation. And having what we call for these kinds of genes an autosomal dominant inheritance pattern, so inherited from either parent. And taking only 1 copy that is not functioning to give a person higher risk of the condition. So that's sort of a bit of the basics here on genetic or hereditary risk. And just to give a sense of how common hereditary breast cancer is, we think that in general this may account for, I would say, somewhere between 5% to perhaps 10% of cases of breast cancer. And Kristen, please jump in and tell me if you think differently. But that would be my ballpark. And I think probably the majority of those are the BRCA1 and BRCA2 genes that I mentioned, although there are others that we are recognizing are playing more of a role than we thought, and we'll discuss those, too. So let me give you a chance to continue and respond, Kristen. Kristen Shannon: Yeah, no, I totally agree. And I was thinking that maybe I could talk a little bit about some of the features that are suggestive that there could be one of these inherited breast cancers in the family, because recognizing these signs of hereditary breast cancer can be super important for early detection and prevention of breast cancer. So first, multiple cases of breast cancer within the family, especially among close relatives like parents, siblings, children, those can be a sign that the cancer is inherited. Another important sign is early age of onset of disease. So breast cancer diagnosed at a young age, typically before the age of 50, might point towards hereditary risk. And it's not always the case, but it's something to be aware of. Also, if there is a history of ovarian cancer in the family, especially if you see it in conjunction with breast cancer cases, that's a significant sign that there could be something inherited in the family. And while it's rarer, male breast cancer can also be associated with hereditary gene mutations. So if there's a history of male breast cancer in the family, it's definitely something to think about in terms of hereditary risk. Multiple cancer types in the family can also be another clue. It's not always just breast and ovarian cancer. If you see a family history of both breast and ovarian cancer or pancreatic cancer or prostate cancer within the same family, that also might be a sign of an inherited cancer syndrome. For individuals of Ashkenazi Jewish descent, it's worth noting that they have a higher prevalence of certain gene mutations in specific genes, specifically BRCA1 and BRCA2, which Dr. Kurian has mentioned before. So a family of history of breast or ovarian cancer in an Ashkenazi Jewish individual should be noted as a higher sign that this cancer could be due to an inherited gene. And lastly, if someone has had breast cancer in both breasts, that's called bilateral breast cancer, and that might indicate hereditary risk. It's important, though, to remember that it's not just about any single sign in isolation. You really need to take a look at the bigger picture and the bigger context of the family. So if you notice any of these signs in your family, it's a good idea to seek guidance from a health care professional, like a genetic counselor or a medical oncologist, and they can help assess the family's risk and recommend genetic testing if needed. Dr. Kurian, did I forget anything or leave anything off? Dr. Allison Kurian: Perfect as always. I will just add a little bit here in terms of the specific gene names that we think about, because sometimes it helps people to have sort of a list in their minds, not that we expect you to remember the whole alphabet soup of these different genes. And let me just say that I think it's always a bit of a hodgepodge, some of these names. I used to wonder how people come up with these names, and often there's a bit of a history there. But I will just go through a few of them. We now have some practice guidelines, and they are basically put together by a group of experts who review all the evidence frequently and come up with recommendations. And so there is a list in these guidelines of basically which genes we think are appropriate to test for breast cancer in families, because there's enough evidence to suggest that. And so in addition to BRCA1 and BRCA2, the ones that I think of as the most important, and I'll want to hear Kristen's thoughts about this, too, but the ones that we see most often are called ATM. Sounds like a cash machine, unfortunately not, but ATM. CHEK2, C-H-E-K-2, and then one called PALB2, which stands for Partner and Localizer of BRCA2, and is a lot like BRCA2 in its risks. There are some other genes that give breast cancer risks that are less common. One of them, CDH1, is a gene that also causes an increased risk of stomach cancer. There are a few others that we always keep in mind. There's one called PTEN that's very rare that causes a syndrome called Cowden syndrome that I certainly haven't seen much of. Kristen may have seen more, but it's not something we see often and goes with a lot of other features in families. There are 2 genes that I think we recognize more in recent years and like to be sure we test, called RAD51C and RAD51D, and those both give increased risks. And then another one that I always think of as important here is TP53, and that is a gene that causes something called Li-Fraumeni syndrome, which has probably the highest cancer risks of which we know. There's another one, STK11, that gives some risk, NF1. We see these as being less frequent contributors. Those are the ones that I kind of keep in mind. And again, there will not be a quiz on the alphabet soup, but just so you're aware of what kinds of names you might hear. Kristen, please jump in if I've forgotten any or anything else you want to say. Kristen Shannon: No, I think that that's important. I think the only thing that I would add is that some people think when they go in for breast cancer genetic testing, they only are getting the BRCA1 and BRCA2 gene. And it's just important for people to realize that that's not really a complete test at this point, as you mentioned, Dr. Kurian. Dr. Allison Kurian: Totally agree, and thank you. Kristen Shannon: Should we move into how to prepare for a genetic counseling appointment? Dr. Allison Kurian: Please, yes. Kristen Shannon: Sure, okay. So preparing for a genetic counseling appointment for breast cancer risk can be helpful. First and foremost, we suggest that you gather your family health history. So reach out to your relatives and compile as much information as possible about your family's health background. Pay special attention to any instances of breast cancer and ovarian cancer, prostate cancer, pancreatic cancer in the family. And if any family members have had genetic testing, it's really helpful to jot down those test results as well and bring them with you to the appointment. The other thing is to think about your own personal medical history. You know, think about if you've had any past diagnosis, any treatments, surgeries, or medical conditions, especially those related to breast cancer, your genetic counseling appointment will include a discussion of those. The other thing is, you know, if you've had any medical tests related to cancer, it's important to gather those records if they're not already in your hospital's medical record system that you are going to. Another good idea is to just prepare a list of questions that you might want to have answered. So what do you want to know? Are there specific concerns or specific things you're curious about? It's also important to understand what you want to get out of this genetic counseling encounter. Do you want to just clarify your risk of having a gene? Do you want to consider genetic testing? Or do you want to talk about just managing your risk for breast cancer? That's super important to have that in mind before you actually go into your appointment. Lastly, I would consider bringing along a person, a supportive person with you to the appointment. Having someone with you can help provide emotional support because sometimes these visits can get emotionally charged, but it also can help to have someone remember important details that you will discuss with your health care provider. So it's really important to just arm yourself with information, questions, and support so that the appointment is as productive and informative as it can be. Do you have anything else you'd like to add, Dr. Kurian? Dr. Allison Kurian: It's wonderful to have your expert perspective on this. And I guess any thoughts about really what's inside the box? I think sometimes people just sort of wonder what's going to happen when I go in that room. Sometimes we have patients come in and say, “What are you guys going to do to me? Will there be surgery done?” And we reassure them that we are not doing anything that wild. And so maybe just a sense of kind of walking people through what will happen when they go to meet with genetic counselors. Kristen Shannon: Absolutely, thanks for bringing that up. So during the initial meeting, first you'll probably discuss your personal health history, again, any past diagnoses, surgeries, medical conditions. And then typically a genetic counselor or a medical professional will dive right into your family health history. So they'll ask a whole bunch of questions about your close and extended family members to build a really comprehensive picture of your family and the cancer diagnosis in it. They'll want to know if anyone in your family has had cancer, and they'll also want to know what type of cancer that person has had and also the age at which that person was diagnosed. So those are the 3 pieces of information that your health care provider will want to get from you. The genetic counselor will also probably ask you about what you want to get out of this encounter to make sure that you're both on the same page. Again, do you want genetic testing? You know that already. Or do you want to just talk through the process? So the big part of the initial meeting is really education. The genetic counselor will explain what Dr. Kurian described at the very outset of this discussion, what's the genetic basis of hereditary breast cancer, including all the specific genes that Dr. Kurian—the alphabet soup that we talked about. Talk about inheritance patterns and the implications of having a genetic mutation. The genetic counselor will probably also first assess your risk of having a mutation in one of the genes, and then they'll also talk to you often about genetic testing. So if genetic testing is on the table and you and the genetic counselor both agree that it's a good step, they'll walk you through the process of informed consent. And so this ensures that you understand what the testing entails, the potential outcomes, the implications of the test results. And then if you decide to go through with genetic testing, you will provide a blood or a saliva sample. And then it's a waiting game because these test results can take several weeks, usually about 3 to 4 weeks to get the test results back. When the test results come back, you'll typically have a follow-up appointment, either in-person or on the phone with your genetic counselor. And that's when they spend a lot of time interpreting the test results, explain what they mean for you and your health, as well as discussing the appropriate risk management strategies, if necessary. And if a gene mutation is identified, a genetic counselor will guide you on how to manage these risks. But it will depend on the specific mutation that is identified. And then the other thing that the genetic counselor can help with is just the emotional support. Some people have a harder time than others hearing this information. And also to talk about how to tell your family members about this. So in a nutshell, the initial meeting with the genetic counselor is about gathering information, assessing risk, and potentially deciding on whether or not you're going to have genetic testing. And then after that step, it's about interpreting the test results, talking about next steps, and providing emotional support. Dr. Allison Kurian: Thank you, Kristen. That was wonderful and very complete. And as I was listening to you, first of all, I was thinking about my general admiration for genetic counselors, which is huge. They taught me everything I know about this field. But so also kind of highlighting the key things that a meeting with a genetic counselor will do for you, as you so nicely did. And I think it's getting the right test ordered, making sure that the results make sense to you, and going beyond the patient. But I think those are sort of the key aspects that you communicated really well of the things that we want to get done there. Kristen Shannon: Well said, well said. And I couldn't agree more. Dr. Allison Kurian: And what do you think about the family part in terms of how that gets done? Kristen Shannon: Right, so discussing your genetic test results with family members can be hard and challenging, but it's really, really important. In terms of talking to your family members, I think first, determine the way you're going to notify your family members. So are you going to talk to them? Are you going to send them a letter or an email? And how you share the information may be different based on your relationship with that person. So for example, you may sit down over coffee with a close family member to talk about your test results, but you may choose to write a letter to someone that you don't have that much contact with. The next thing that I think is really important is to be prepared. So before you even start to have this conversation, make sure that you have a clear understanding of your genetic test results, the implications to you and to the family member. That's super important before you even start to have the conversation so that you can explain things to people in simple terms without too much medical jargon and make sure you keep it straightforward. It's really helpful to have a copy of your genetic test results and to provide that to your relatives if you're comfortable doing so, because then they can take that information with them to their genetic counseling or genetic testing appointment, which can be incredibly essential in terms of making sure that they get the correct test at the right time and the test results are interpreted correctly. The only other suggestion I have is just to keep in mind that family members are going to react very differently to this information. And some people will be very matter of fact about it. Some people might get a little distracted by this whole thing. So just to be patient with people and keep the conversation open. Allow them to call you if you're willing to do that so that the conversation can develop over time because, you know, really, in the end, the goal is to make sure that everyone in the family is well informed and makes decisions based on their own health and their well-being. Dr. Allison Kurian: Thank you. I couldn't agree more. And we sometimes, as people may have heard, call this “cascade genetic testing.” So a patient is tested. Somebody who's already had cancer maybe is tested. But then we have the opportunity to have this cascade of beneficial genetic testing, where we can get to people before they have cancer and work on prevention and screening, which I'll talk about in a minute. And I will say that, in general, we here in the United States, and certainly other places as well, don't do as well as we would like with cascade testing despite all best efforts of everyone. And so just to emphasize that family notification is super important, genetic counselors are wonderful at helping people to do that. And I think also additional strategies and interventions are underway to try to help make that easier. So if I may, I'll talk just a little bit about kind of what we do when we find something. Is that okay to do? Kristen Shannon: That sounds great. Talk about people, you know, what they can do about their test results. Dr. Allison Kurian: Good. Yeah, so I always think that's important. I'm an oncologist by training. I'm not a geneticist. And again, it's only thanks to the brilliance of genetic counselors like Kristen that I have learned what I have for the last 2 decades working in the field. But so I tend to think in terms of what can we do to treat this person differently if they have cancer to prevent or reduce the risk of a future cancer. And so what I would say is increasingly over the last few years for a person with breast cancer, as well as some additional cancers, it started to matter what these results are in terms of how we treat the person, whether we might give different medications. And that's really exciting because for years in this field, we didn't have that, and now we do. And so the drugs that are increasingly important are called PARP, P-A-R-P, inhibitors. And sometimes, if a person has a BRCA1 or BRCA2 gene mutation, we might even offer those drugs to treat a breast cancer or, in other cases, ovarian, prostate, or pancreatic cancer. So I think the testing can matter like never before in terms of what we might do to take care of people's cancer. Sometimes we might also choose a different surgery. So sometimes a woman who has a diagnosis of breast cancer might choose to do a more extensive breast surgery, she might choose a double mastectomy to reduce her risk of getting a second breast cancer. That's never required. She certainly doesn't have to do so extensive a surgery if she doesn't choose, but it is an option that some people might choose. And there might also be other cancer risks to manage in somebody who had breast cancer. BRCA1 and BRCA2, for example, give a high risk of ovarian cancer. And so we might talk with someone about the possibility of removing ovaries to prevent an ovarian cancer, which often is recommended with BRCA1, BRCA2, and other such gene mutations. I will say that I think for somebody who hasn't had cancer yet, or hopefully ever, particularly as we think about breast cancer, we're often thinking about intensive screening. So starting often earlier than a person would if she didn't have high risk and generally adding magnetic resonance imaging, MRI, to screening with mammogram alone. And that really is, I think, the cornerstone for women at high risk is adding that breast MRI screening. For pretty much all of the genes I mentioned, that would be clinically indicated and covered by insurance and important to do. MRI has no radiation, very effective at finding breast cancer early. So I think to summarize, it's really all about understanding risk based on a particular gene mutation, understanding if a different kind of treatment is needed for the cancer that a person has, understanding if any sort of preventive measure is needed for future cancer risk, and making sure that the screening we have for breast and for other cancers is appropriate to the level of risk. Anything to add there, Kristen? Kristen Shannon: No. No, I think that that's great. Dr. Allison Kurian: Absolutely. Yeah, so I think it's wonderful to have this opportunity to speak about the importance of genetic testing, which is I think more important than it ever has been at this time for the care of patients with breast cancer and their families. And so as we move into breast cancer awareness month, it's great to be able to talk about this. Thanks so much. Kristen Shannon: Thank you so much. I agree. And if you have any questions, I would suggest you reach out to your doctor or look up on the ASCO website for a referral to a genetic counselor. ASCO: Thank you, Dr. Kurian and Ms. Shannon. Learn more about hereditary breast cancer and genetic testing at www.cancer.net/hboc. Cancer.Net Podcasts feature trusted, timely, and compassionate information for people with cancer, survivors, and their families and loved ones. Subscribe wherever you listen to podcasts for expert information and tips on coping with cancer, recaps of the latest research advances, and thoughtful discussions on cancer care. And check out other ASCO Podcasts to hear the latest interviews and insights from thought leaders, innovators, experts, and pioneers in oncology. Cancer.Net is supported by Conquer Cancer, the ASCO Foundation, which funds lifesaving research for every type of cancer, helping people with cancer everywhere. To help fund Cancer.Net and programs like it, donate at CONQUER.ORG/Donate.
A wild Rapid Fire Question Challenge appears! Season 3's 1st RFQC actually is a throwback to a couple Season 1 guests whose rapid fires never got released. The first challenger is Jennifer O'Donnell, translator & localizer who joined us for Season 1 Episode 15 called "Careers in Japanese: Translation & Localization". In that episode, we explored how to leverage Japanese language study into a career in translation and a peek behind the industry's curtain. After Round 1 finished, Megan DeVille stepped up onto the RFQ Challenge stage. Megan was our guest on Season 1 Episode 17 entitled "Accepted for JET Program... Now What?!". Megan recalls her JET Program application process, as well as talks about her experiences mentoring (and interviewing) prospective JET applicants. A fun mini-episode to hold us over until next week's episode on food-based travel, featuring an awesome conversation with Shinichi of the popular YouTube channel, TabiEats!------ About the Krewe ------The Krewe of Japan Podcast is a weekly episodic podcast sponsored by the Japan Society of New Orleans. Check them out every Friday afternoon around noon CST on Apple, Google, Spotify, Amazon, Stitcher, or wherever you get your podcasts. Want to share your experiences with the Krewe? Or perhaps you have ideas for episodes, feedback, comments, or questions? Let the Krewe know by e-mail at kreweofjapanpodcast@gmail.com or on social media (Twitter: @kreweofjapan, Instagram: @kreweofjapanpodcast, Facebook: Krewe of Japan Podcast Page, TikTok: @kreweofjapanpodcast, & the Krewe of Japan Youtube Channel). Until next time, enjoy!------ More Info on Jennifer O'Donnell ------JEN Translations BlogJennifer on TwitterOur Episode with Jennifer from Season 1 (Apple)Our Episode with Jennifer from Season 1 (Spotify)Translation Chat Podcast------ More Info on JET Program ------JET Application Online (USA site)USJETAA website (US JET Alumni Association National)Our Episode with Megan from Season 1 (Apple)Our Episode with Megan from Season 1 (Spotify)JETAA Mid-South - JET Program Alumni Association Chapter for New Orleans, Mississippi, & Arkansas
On FSCast 199, a recording of Glen Gordon’s presentation at the National Coding Symposium, a recent virtual event put on to encourage high school students to think about careers involving programming. Then, a visit with Rocio Casati, the person who’s been making our products work well in Spanish for over twenty years. The process of doing that is far more involved than you might think. Transcript available at blog.freedomscientific.com/fscast
Localizer Back Course ApproachWatch the video versions at www.wificfi.comwifiCFI by Axiom AviationSupport the show (http://www.wificfi.com)
Localizer ApproachWatch the video versions at www.wificfi.comwifiCFI by Axiom AviationSupport the show (http://www.wificfi.com)
118 Instrument Flying and IFR Listener Questions + General Aviation News Your Cirrus Specialist. Call me if you're thinking of buying a new Cirrus SR20 or SR22. Call 1-650-967-2500 for Cirrus purchase and training assistance, or to take my online seminar: So You Want to Fly or Buy a Cirrus. Please help support the show with a donation via PayPal or Patreon. Send us an email If you have a question you'd like answered on the show, let listeners hear you ask the question, by recording your listener question using your phone. Summary118 GA news plus Max answers listeners questions on Instrument Flying and IFR including questions about how to save money on an instrument rating, using a simulator to get an instrument rating, when to switch from GPS to the Nav radio on localizer and VOR approaches, Legally using GPS on the entire VOR approach, whether to train in a round gauge airplane or a glass cockpit like in a Cirrus. News Stories FAA investigates report of Boston MedFlight pilot falling asleep Thieves Break Into At Least Nine Airplanes In N.H. Southwest Airlines Launches New Pilot Pathways Program Senator seeks input from GA pilots Pilot in Mesquite crash landing denies drinking and flying FAA: ICAO Flight Plan Format Becomes Mandatory Unleaded avgas for sale at KSQL Family sues FAA over crash, claims ATC gave pilot false information Silver Spitfire departs on round-the-world flight Boy who stole two planes for a joyride could receive pilot training Jessica Cox To Take Delivery Of Her First Airplane Mentioned in the ShowHow to Complete an ICAO Flight PlanSummary of Sen. Inhofe's Aviation bill Silver Spitfire Around-the-World Flight Tracker Max on Plane Talking UK #279 podcast Icon A5 crash video Icon A5 Wheeling, IL crash found by pinging cell phone Icon Workforce Reduced by 40 Percent NTSB: Pilot Error in Icon Crash in Wheeling, IL Flying Companion Seminar by 99s in San Jose, CA Airport Restaurants website If you love the show and want more, visit my Patreon page to see fun videos, breaking news, and other posts in the Posts section. And if you decide to make a small donation each month, you can get some goodies! So You Want To Learn to Fly or Buy a Cirrus seminars Online Version of the Seminar Coming Soon - Register for Notification Check out our recommended ADS-B receivers, and order one for yourself. Yes, we'll make a couple of dollars if you do. Check out our recommended Aviation Headsets, and order one for yourself! Get the Free Aviation News Talk app for iOS or Android. Please Take our 2019 Social Media Survey. I'd love to understand how you use, or don't use, social media, so I can target social media posts and advertising for Aviation News Talk to other people similar to you. Social Media Follow Max on Instagram Follow Max on Twitter Follow Max on YouTube Listen to all Aviation News Talk podcasts on YouTube or YouTube Premium Max Trescott is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to amazon.com.
Alessio got a chance to sit down and chat with the bad boy of games translation himself, Jeremy Blaustein. The entire team at Metal Gear Mondays is extremely grateful that Jeremy took time out of his schedule to connect with us, and strongly encourage everyone to follow along with his work at his website or via his Twitter. Support the show (http://patreon.com/metalgearmondays)
Last week we talked about briefing the approach and said one of the first things you should do is check to see whether GPS is in the title of the approach. For example, you might look to see whether the title is just VOR 21 approach or if it’s VOR 21 OR GPS. If it’s the latter, it’s obvious you can use GPS in lieu of a VOR signal for the entire approach. But what’s less clear is when you can use GPS for a portion of the approach if it says just VOR 21 and doesn’t have GPS in the title of the approach. Although GPS receivers have been around for over 20 years, pilots are still unclear as to when they can use GPS on non-GPS approaches such as ILS and VOR approaches. As Max explains, the rules are different for VOR and ILS approaches. The regulatory basis can be found in FAA Advisory Circular AC 90-108, dated March 3, 2011, and in the AIM, the Aeronautical Information Manual, in section 1-2-3, sub-paragraphs c4 and c-5, updated May 26, 2016. These tell us that for a VOR or NDB approach, you can now use GPS for the entire approach, even if GPS is not listed in the title of the approach. So in our example, if the title of the approach is VOR 21, and GPS is not in the title, you can still now use GPS for the entire approach, but with one caveat. The VOR or NDB signal MUST be in service, and you MUST monitor that signal for the final approach course. But for an ILS or Localizer approach, as soon as you turn onto a localizer or ILS, you need to display course guidance from the Nav radio. On the Garmin 430/530, that means as soon as you turn onto the localizer, you must push the CDI button so VLOC is displayed. You can, if you wish, monitor RNAV (GPS) data as you fly along a localizer, but GPS cannot be used for primary guidance at any time while on a localizer. Click here for the listener survey. Tell us what what ADS-B portable receiver you own or plan to buy, and what you like and dislike about it. Please visit my new Patreon page and make a contribution to help me with my goal of improving the AviationNewsTalk.com website. You can Dictate a listener question from your phone and I’ll try to answer it on a future show, or send an email. News Stories Airliner Reportedly Narrowly Avoids Hitting Glider Air National Guard Restores Air Traffic Control in Puerto Rico Shuster Takes Aim at 'False Claims' on ATC Proposal American pilot in New Zealand says system there has wrecked GA Dick Smith calls for aviation report to be released Radar Failure in Sydney, Australia First 10 Deposits Received for “Sun Flyer 4” Bruce Landsberg to Join the NTSB FAA Gives Pilots Thumbs Up To Fly Rude Banners Over Chargers Home Games Old Stapleton air traffic control tower set to open as new Punch Bowl Social
This week's question is from Paulo, who asks "In terms of the gaming industry, the topic that matters to me the most is video game localization. I'm a Brazilian translator and I would love to translate games as well. I don't know if you have already written anything about that, but I would love to know more if possible." LINKS FROM THIS EPISODE http://www.keywordsstudios.com/en/careers Thanks for listening! You are the wind beneath my wings. To ask me a question to be answered on this podcast, just leave a comment or send an email. For more information on getting a job in video games, visit: http://www.GameIndustryCareerGuide.com
The long wait for a new Chic Pixel Plus episode is finally over, and I think you’re all in for a treat! Following episode 3’s Japanese language and game-centric podcast, I was lucky enough to snag freelance translator Gabe Glick for a great discussion on game localization, Japanese language learning, and raising a family in… Read More The post Chic Pixel Plus Episode 4 – Freelance Game Localizer Extrodinare appeared first on Chic Pixel.
The Silent Comedy - Impossible Name Transfer - You are the Wolf Anna Troy - Aint No Man Augustana - I Still Aint Over You Louis XIV - Air Traffic Control Get Back Loretta - Dreams Got Scattered Larger than Life - You Monster You The Blackout Party - Daughter of a Drunk The Bloody Hollies - Satanic Satellite The Delta Spirit - Trashcan
Crash Encore - Vagabond Transfer - Sinking Sailing Reeveoliver - I Want Burns Augustana - Sweet and Low The Silent Comedy - Bones Berkley Hart - Sink or Swim Switchfoot - Dare You to Move (Pyles Session) Greg Laswell - Girls Just Want to Have Fun Louis XIV - Guilt by Association Get Back Loretta - Gotta Believe
How Critzler started designing fonts, hooking up with Die Gestalten publishers and the Localizer book and font. Critzlerâs early fonts for Linotype :: Localizer book :: Localizer font :: File Download (9:02 min / 10.4 MB)
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