Podcasts about Tissue

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What does it take to stop avoiding pain and instead use it as a guide for rebuilding the body? The same movements that caused injury can heal it when performed slowly, partially, and with intention. "What we try to do is get people to understand that if you have pain, if you have a limitation, you don't stop doing the thing that hurt it. You do the thing that hurt it, slow, partial, light, take it down to the baby amount, the tolerable amount, and then start pushing it back up the scale. And by the time you can do it fast and heavy again, you're healed. Congratulations." ~ Sean Hannah (9:19) The conversation explores why most people avoid the slow, deliberate work required to truly rehabilitate injuries rather than just return to basic function. The distinction between physical therapy (designed for baseline recovery) and full joint remodeling (a months-to-years process typically reserved for elite athletes) forms the foundation of the discussion. The key insight is that healing requires doing the same movements that caused injury—but slower, lighter, and more partial—rather than avoiding them entirely. Pain emerges as a multifaceted phenomenon with three distinct layers: actual tissue damage, neuropathic pain (trauma responses encoded in nerves and fascia), and centralized pain (psychological amplification based on beliefs and language). The conversation addresses how someone might present with a knee problem but actually need a full head-to-toe biomechanical remodel, with the knee simply being where the dysfunction surfaces most visibly. The discussion also touches on the origins of the nickname "Seanobi" (an Irish ninja wordplay), the value of intuitive three-dimensional movement versus linear athletic training, and the importance of having something worth playing for as the motivational spark that makes the difficult rehabilitation process possible. Takeaways Remodeling versus physical therapy — Physical therapy aims for basic function, but returning to athletic capability requires a separate, longer process called remodeling that most people don't know exists. The spark — Without something you love doing that's disappearing or already gone, you won't sustain the slow, frustrating work of rehabilitation. Same movements, different parameters — Healing doesn't require new exercises; it uses the same movements that caused injury, performed slower, lighter, and more partially. Three layers of pain — Pain includes actual tissue damage, neuropathic responses stored in nerves and fascia, and psychological amplification based on perception and language. Language affects pain signaling — The words used to describe pain directly influence how much pain is felt; changing the narrative can dampen signaling and allow greater loading. The blowout point — A presenting injury like a knee problem is often just where a full-body biomechanical imbalance surfaces most visibly. Tissue-specific protocols — Pace, load, and angle can be adjusted to target specific tissues: nerve and fascia respond to different parameters than muscle and bone. Guarding responses — Much of chronic pain isn't damage but protective contractions and nerve issues that require precise loading to release. Threading the needle — Effective rehabilitation requires enough stress to trigger healing responses without crossing the threshold into new damage. Intuitive versus linear training — Three-dimensional, intuitive movement serves rehabilitation and durability, while linear athletic training like Olympic lifting builds speed and power for sport. The dial metaphor — Training exists on a spectrum from slow, rehabilitative, three-dimensional work to fast, linear, athletic work, and the dial can be adjusted based on daily capacity. Becoming your own maintenance mechanic — The goal of guided rehabilitation is independence—learning to address pain and maintain the body without ongoing professional help. Resources Monkey Do — "What Moves You?" Sean Hannah's guided mobility and joint remodeling programs. Monkey Do on YouTube — video content related to the mobility and rehabilitation approach. Designing curriculum, teaching seniors, and the mid-range — Sean's previous conversation on Movers Mindset covering related topics. Katy Bowman — mentioned regarding how too much "vitamin flat and level" is a problem. Iron Gump / MIST — a Movers Mindset conversation discussing meditative strength training. Parkour Generations — the organization behind American Rendezvous where Craig and Sean last met in person. (Written with help from Claude.ai) --- Hello

The Intro to AOX Course is coming to Tempe, AZ! Join us for a hands-on deep dive into the clinical and business systems behind predictable full-arch success. Seats are limited - register now to secure your spot. https://products.sharedpractices.com/tfap-intro-to-aox-2026 In this episode of The Full Arch Podcast, Dr. Leke Olowokere sits down with Dr. Tomasz Kaczyński to discuss one of the most overlooked drivers of long-term full-arch success: soft tissue management. While implants and bone often dominate treatment planning, this conversation reframes tissue as a biologic foundation for stability. They explore why soft tissue plays a different role in FP3 full-arch cases compared to single-tooth restorations, with a particular focus on the mandible. Dr. Kaczyński shares how tissue quality and biologic principles influence long-term stability and complication risk in full-arch treatment. Key Highlights:

TODAY ON THE ROBERT SCOTT BELL SHOW: LIVE from Atlanta! Vaccine Choice Debate, California Joins WHO, BPA Gender Disruption, Microplastic Sky Shock, Vespa Crabro, WEF Lab-Meat Agenda, Florida Vaccine Exemption Bill, Fetal Tissue Ban, Moderna Pullback, Candy Arsenic Scandal, and MORE! https://robertscottbell.com/vaccine-choice-debate-california-joins-who-bpa-gender-disruption-microplastic-sky-shock-vespa-crabro-wef-lab-meat-agenda-florida-vaccine-exemption-bill-fetal-tissue-ban-moderna-pullback-candy/https://boxcast.tv/view/live-from-atlanta-vaccine-choice-debate-california-joins-who-bpa-gender-disruption-fetal-tissue-ban---the-rsb-show-1-28-26-p6svpropdqhrs63p6vuw Purpose and Character The use of copyrighted material on the website is for non-commercial, educational purposes, and is intended to provide benefit to the public through information, critique, teaching, scholarship, or research. Nature of Copyrighted Material Weensure that the copyrighted material used is for supplementary and illustrative purposes and that it contributes significantly to the user's understanding of the content in a non-detrimental way to the commercial value of the original content. Amount and Substantiality Our website uses only the necessary amount of copyrighted material to achieve the intended purpose and does not substitute for the original market of the copyrighted works. Effect on Market Value The use of copyrighted material on our website does not in any way diminish or affect the market value of the original work. We believe that our use constitutes a 'fair use' of any such copyrighted material as provided for in section 107 of the U.S. Copyright Law. If you believe that any content on the website violates your copyright, please contact us providing the necessary information, and we will take appropriate action to address your concern.

Wednesday 28 January 2026 To hear the fascinating FULL discussion, become a MEMBER today and enjoy this and other full featured content. #image_title   “Reconquest” is a militant, engaging, and informative Catholic radio program featuring interviews with interesting guests as well as commentary by your host. It is a radio-journalistic extension of the Crusade of Saint Benedict Center.

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Send us a textThis week, Heather and Vanessa explore all things tissue salts, aka cell salts. We  explore the question of whether true healing is about adding more supplements, or could it be about restoring the mineral foundation your body was designed to run on. To answer that, we explain what tissue salts are, how they work, their connection to homeopathy and astrology, and why mineral balance may be one of the most overlooked keys to chronic healing.You'll learn:• What tissue salts are and why they matter at the cellular level• How minerals influence energy, emotions, detox, and hydration• The relationship between tissue salts, homeopathy, and structured (EZ) water• The astrology connection, and how your chart may reveal mineral weaknesses• Simple ways to use tissue salts safely and intuitivelyTissue salts don't force the body, they remind it. By restoring mineral balance, we restore communication among cells, emotional resilience, and the body's innate ability to heal. Your cells remember how to heal; sometimes, they just need the right minerals to remind them.If you're ready to explore your unique mineral map, learn more about personalized consultations, you can take Vanessa's Tissue Salts course, and read her ongoing series on Substack.Ready to go deeper into the mineral language of your body?Vanessa's Cell Salts CourseA guided journey into the 12 tissue salts helping you understand how minerals shape your energy, emotions, digestion, hormones, and healing at the cellular level.Link to the Cell Salts CourseLink for Vanessa's SubstackFacial Diagnosis of Cell Salt Deficiencies: A User's Guide Schuessler's Tissue Salts Rediscovered: The 21st Century Guide to Self-HealingSupport the showFind Heather:https://calendly.com/enlightenedmoodhttps://www.instagram.com/enlightenedmood/Discount codes:https://www.vivarays.com ➡️ Code: enlightenedmood.comhttps://midwestredlighttherapy.com/affiliate/enlightenedmood/ https://www.emr-tek.com/enlightenedmood ➡️ Code: enlightenedmood Find Vanessa:https://instagram.com/bright_light_wellness/vanessabaldwin/Website: https://brightlightwellnesscoach.com/Discount codes:Free Product Guide http://gem.godaddy.com/signups/3cdbe47a101a4d2d9b991e9b5c9a981e/join Free Homeopathy Guide http://gem.godaddy.com/signups/425d2c01be2848b79193824b3e00c71f/join

WMAL GUEST: MARJORIE DANNENFELSER (President of Susan B. Anthony Pro-Life America) on today’s March for Life rally in D.C. and the Trump administration’s immediate halt to NIH-funded research involving human fetal tissue READ: Vance to Headline March for Life SOCIAL MEDIA: @MarjorieSBA Where to find more about WMAL's morning show: Follow Podcasts on Apple Podcasts, Audible and Spotify Follow WMAL's "O'Connor and Company" on X: @WMALDC, @LarryOConnor, @JGunlock, @PatricePinkfile, and @HeatherHunterDC Facebook: WMALDC and Larry O'Connor Instagram: WMALDC Website: WMAL.com/OConnor-Company Episode: Friday, January 23, 2026 / 7 AM HourSee omnystudio.com/listener for privacy information.

It's our first fresh NMF of 2026 and we are off to a flying start! If this chook is listening, we need a follow-up with the extra tea!! LINKS Send your Nightmare Fuel to hello@itsalotpodcast.com Check out @itsalotpod on IG at https://bit.ly/itsalot-instagram Review the podcast on Apple Podcasts https://bit.ly/ial-review Follow LiSTNR Entertainment on IG @listnrentertainment Follow LiSTNR Entertainment on TikTok @listnrentertainment Get instructions on how to access transcripts on Apple podcasts https://bit.ly/3VQbKXY CREDITS Host: Abbie Chatfield @abbiechatfield Executive Producer and Editor: Amy Kimball @amy.kimballDigital and Social and Video Producer: Oscar Gordon @oscargordon Social and Video Producer: Justin Hill @jus_hillIt's A Lot Social Media Manager: Julia ToomeyManaging Producer: Sam Cavanagh Find more great podcasts like this at www.listnr.com/See omnystudio.com/listener for privacy information.

This episode of TTCL will feature an interview with Luis Santiago from NFH on La Mega. This monthly interview will inform the Spanish Community about Network For Hope and the incredible miracles that happen with Organ, Tissue, and Eye Donation. Resources: https://getoffthelist.org/ https://www.networkforhope.org/ https://www.networkforhope.org/about-us/ https://www.facebook.com/NetworkForHopeOPO https://aopo.org/ RegisterMe.org/NetworkforHope

In the final installment of this series, Dr. Justin Abbatemarco and Dr. Divyanshu Dubey discuss the latest findings and some non-occupational exposures.  Show citation:  Hinson SR, Gupta P, Paramasivan NK, et al. Neural synaptic vesicle autoimmunity following aerosolized porcine neural tissue exposure: insights into autoimmune inflammatory polyradiculoneuropathy. EBioMedicine. 2025;122:106053. doi:10.1016/j.ebiom.2025.106053 Show transcript:  Dr. Justin Abbatemarco:  Hello, and welcome back. This is Justin Abbatemarco. I'm here with Divyanshu Dubey, discussing his article, Neural Synaptic Vesicle Autoimmunity Following Aerosolized Porcine Neural Tissue Exposure: Insights Into Autoimmune Inflammatory Polyradiculoneuropathy. Div, maybe we could talk about non-occupational exposures? I think many of us don't see this cohort of patients commonly, but I really think this helps inform care, beyond just this specific occupational exposure. What did you guys find in your work? Dr. Divyanshu Dubey:  So, one of the inspirations for this study was driven by the phenotypic characterization of patients who were described in this 2010 paper, which is somewhat similar to some of the patients I currently see in my clinic who don't seem to meet GBS or CIDP criteria. But, based on their MRI findings, based on their CSF studies, the EMG nerve conduction studies, they seem to have this polyradiculoneuropathy presentation, often presenting with asymmetric disease onsets, starting on one leg and then sometimes transitioning to the other side. In some cases, even a non-length dependent pattern with sort of proximal cervical brachial nerve root plexus involvements, which don't really seem to have a blood test, or a biomarker right now. Currently, many of these cases are a diagnosis of exclusion. I was thinking if there's a biomarker that we can identify from this 2006 to 2008 unfortunate event, that might actually help us diagnose these patients. So, once we identified synaptophysin and GAP43 antibodies in the swine abattoir cohort, I went back to our storages of these patients with other inflammatory polyradiculoneuropathy, and found about 5% of these patients from a large cohort of close to 300 patients, did have these antibody biomarkers. Some of these patients had paraneoplastic trigger, where we had patients with neuroendocrine tumors, or hematological malignancies mounting a response to these antibodies. But a good chunk of these patients we did not truly understand, or know what the triggers were. That might be a potential for future studies, as we expand our cohort of these antibodies, as well as study further the phenotypic characterization of these cases. Dr. Justin Abbatemarco: Yeah, there's just so much there, really helping to inform future clinical care outside of this very specific occupational exposure. And then, as we talked about in the podcast, I think really helping to think through how neurological autoimmune diseases develop. So, just really exciting work. We really appreciate you coming on, sharing this. We're excited for how this evolves over the coming years. Dr. Divyanshu Dubey:  Thank you, Justin.  

In part one of this two-part series, Dr. Justin Abbatemarco and Dr. Divyanshu Dubey discuss the original patient cohort with occupational exposure, what motivated this line of research, and the key findings from the initial workup.  Show citation:  Hinson SR, Gupta P, Paramasivan NK, et al. Neural synaptic vesicle autoimmunity following aerosolized porcine neural tissue exposure: insights into autoimmune inflammatory polyradiculoneuropathy. EBioMedicine. 2025;122:106053. doi:10.1016/j.ebiom.2025.106053 Show transcript:  Dr. Justin Abbatemacro: Hello and welcome. This is Justin Abbatemacro. And I'm here with Divyanshu Dubey to discuss his article published in eBiomedicine, Neurosynaptic Vessel Autoimmunity Following Aerosolized Porcine Neural Tissue Exposure: Insight into Autoimmune Inflammatory Polyradicular Neuropathy. Dr. Justin Abbatemacro: Div is a professor of neurology at the Mayo Clinic, and we just finished our interview, which I would encourage everyone to check out. Div, maybe we could talk about the original cohort with this occupational exposure, what inspired you to do this work and then what did you find with that initial workup? Dr.  Divyanshu Dubey: As recounted in our paper, this story began in 2006 to 2008, when a group of swine abattoir workers developed a striking neurological syndrome. These people were previously healthy and suddenly developed severe neuropathic pain, tingling, and variable weakness. The localization stood out, these cases were initially identified by Dan Lachance, who characterized these patients having an autoimmune neuropathy, which was further phenotypically characterized by the work done by Dr. Dyck, calling these inflammatory polyradicular neuropathy based on their nerve root plexus and proximal nerve collisions. And interestingly, a lot of work done back then by Dr. Lennon showed these patients had a unique synaptic staining pattern suggesting there was an underlying antibody driving this disease process. So as I joined the neuroimmunology lab a few years ago, this was one of the areas I wanted to go back and study, not only to find this mystery biomarker which caused the disease in these patients, but also to try and understand how this can help. Dr. Justin Abbatemacro: Yeah. I think my takeaway is be curious, right? You hear the story, you see this pattern. Be curious and investigate, and it takes a team or a village to do it. Dr.  Divyanshu Dubey: 100%. So observation, communication between, as you said, a team or a village with like-minded, passionate individuals is one of the successes of many of our discoveries, not just this one in this biomarker space. Dr.  Divyanshu Dubey: So the technique we use for discovery of these biomarkers was called a phage display where we use the archive sera to test from these patients, the swine abattoir worker patients with autoimmune polyradicular neuropathy. And we ended up finding two dominant antigens, which was synaptophysin and GAP-43, which were present in majority of these cases. Dr. Justin Abbatemacro: Please come back and check out part two where we discuss the latest findings and maybe some non-occupational exposures. And check out the podcast. Thanks.  

Do you carry a handkerchief?With the winter colds and flus in full flow, some people are opting to ditch the manky tissue in favour of a luxury handkerchief...Louis Copeland would be a handkerchief man arguing that a pocket square is key to completing any look…He joins Seán to discuss.

Dr. Justin Abbatemarco talks with Dr. Divyanshu Dubey about how antibodies to synaptophysin and GAP43 help explain an autoimmune neuropathy seen in swine abattoir workers and offer new clues for diagnosing and treating related inflammatory neuropathies. Read the related article in ScienceDirect.  Disclosures can be found at Neurology.org. 

In a world obsessed with stimulation and strength, what can this gentle, velvety herb teach us about healing?In this episode, herbalist and prolific author Maria Noël Groves joins me to discuss one of the most soothing herbs around—the lovely marshmallow (Althaea officinalis). Together we explore what makes this mucilaginous (read: velvety, not slimy!) herb such a powerful ally for irritated and inflamed tissues—especially in the gut, where marshmallow helps to protect, moisten, and nourish while also supporting the microbiome.Maria shares why she's fallen so deeply in love with this soft, soothing herb, and how it works without being forceful or stimulating. She also includes a recipe for a cozy, delicious beverage to soothe not just the gut, but also the spirit—her Creamy Marshmallow-Nutmeg Overnight Infusion. You can download your beautifully-illustrated recipe card here.By the end of this episode, you'll know:► The importance of tasting and experiencing an herb in different ways► How best to prepare marshmallow root (and why this is a point of contention among herbalists!)► When marshmallow leaf and flower might be a better medicinal choice than the roots► Why Maria includes marshmallow leaf in most of her tea blends► How marshmallow can help heal your digestion—from cooling inflamed tissues to feeding your gut microbiome (and more!)► When to use caution with taking marshmallow► and so much more…For those of you who don't know her, Maria Noël Groves is a clinical herbalist nestled in the pine forests of New Hampshire. She runs Wintergreen Botanicals, and is devoted to education and empowerment via classes, health consultations, and writing with the foundational belief that good health grows in nature. Maria is the author of the award-winning, best-selling book Body into Balance: An Herbal Guide to Holistic Self Care, as well as Grow Your Own Herbal Remedies, Herbal Remedies for Sleep, and the new Herbal Gut Health.Marshmallow offers an important reminder that some of the most profound healing comes not from pushing harder, but from learning how to soften. I hope this conversation with Maria inspires you to give your body the care, protection, and nourishment it needs in the new year and beyond.----Get full show notes, transcript, and more information at: herbswithrosaleepodcast.comWould you prefer watching this episode? If so, click here for the video.You can find Maria at WintergreenBotanicals.com.If you're interested in Maria's fantastic new book, Herbal Gut Health, you can preorder it here or wherever books are sold.For more behind-the-scenes of this podcast, follow @rosaleedelaforet on Instagram!Working successfully with herbs requires three essential skills. Get introduced to them by taking my free herbal jumpstart course when you

Behzad Najafian, MD, Professor, Department of Laboratory Medicine & Pathology, Department of Medicine at the University of Washington, Washington, USA discusses the use of artificial intelligence in identifying and managing lysosomal disorders.This continuing education activity is provided through collaboration between the Lysosomal and Rare Disorders Research and Treatment Center (LDRTC), CheckRare CE, and AffinityCE. This activity provides continuing education credit for physicians, physician assistants, nurses, nurse practitioners, and genetic counselors. A statement of participation is available to other attendees.To obtain CME/CE credit, visit https://checkrare.com/learning/p-grids2025-session1-ai-in-medicine-transforming-the-landscape-of-tissue-based-diagnostics/Learning ObjectivesDescribe recent advances in the applications of AI in lysosomal disorder diagnosis and its clinical relevanceFacultyBehzad Najafian, MD Professor, Department of Laboratory Medicine & Pathology, Department of Medicine, University of WashingtonDisclosuresAffinityCE staff, LDRTC staff, planners, and reviewers, have no relevant financial relationships with ineligible companies to disclose. Faculty disclosures, listed below, will also be disclosed at the beginning of the Program.Behzad Najafian, MDDr. Najafian is on the Advisory Board/Consultant for Sanofi, Amicus, Avrobio, 4DMT,Sangamo, Freeline, AceLink, Relay, CRISPR, ELOXX, SPARK, UNIQURE. He receives grants/research support from Amicus. Mitigation of Relevant Financial RelationshipsAffinityCE adheres to the ACCME's Standards for Integrity and Independence in Accredited Continuing Education. Any individuals in a position to control the content of a CME activity, including faculty, planners, reviewers, or others, are required to disclose all relevant financial relationships with ineligible entities (commercial interests). All relevant conflicts of interest have been mitigated prior to the commencement of the activity. Conflicts of interest for presenting faculty with relevant financial interests were resolved through peer review of content by a non-conflicted reviewer.Accreditation and Credit DesignationPhysiciansThis activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of AffinityCE and the LDRTC. AffinityCE is accredited by the ACCME to provide continuing medical education for physicians.AffinityCE designates this enduring activity for a maximum of 1 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.Physician AssistantsAffinityCE designates this enduring activity for a maximum of 1 AMA PRA Category 1 Credits™. Physician Assistants should claim only the credit commensurate with the extent of their participation in the activity.NursesAffinityCE is accredited as a provider of nursing continuing professional development by the American Nurses Credentialing Center's Commission on Accreditation (ANCC). This activity provides a maximum of 1 hours of continuing nursing education credit.Nurse PractitionersAffinityCE designates this enduring activity for a maximum of 1 AMA PRA Category 1 Credits™. Nurse practitioners should claim only the credit commensurate with the extent of their participation in the activity.Genetic CounselorsAffinityCE designates this enduring activity for a maximum of 1 AMA PRA Category 1 Credits™. Genetic Counselors should claim only the credit commensurate with the extent of their participation in the activity.Other ProfessionalsAll other health care professionals completing this continuing education activity will be issued a statement of participation indicating the number of hours of continuing education credit. This may be used for professional education CE credit. Please consult your accrediting organization or licensing board for their acceptance of this CE activity. Participation CostsThere is no cost to participate in this activity.CME InquiriesFor all CME policy-related inquiries, please contact us at ce@affinityced.comSend customer support requests to cds_support+ldrtc@affinityced.com

BUFFALO, NY — December 30, 2025 — A new #research paper was #published in Volume 17, Issue 11 of Aging-US on November 26, 2025, titled “Epigenetic aging signatures and age prediction in human skeletal muscle.” In this study, first author Soo-Bin Yang and corresponding author Hwan Young Lee from Seoul National University College of Medicine investigated how DNA methylation patterns in skeletal muscle change with age. Their findings offer a new and highly accurate method for estimating a person's age, with potential applications in forensic science and aging research. Skeletal muscle is essential for movement, energy balance, and physical strength, functions that become more important to monitor as people age. This study improves our understanding of how muscle tissue changes over time at the molecular level. Unlike previous research, which mainly analyzed living individuals of European descent, this study used postmortem samples from an Asian population. “We analyzed DNA methylation profiles from 103 pectoralis major muscle samples from autopsies of South Korean individuals (18–85 years) using the Infinium EPIC array.” The researchers analyzed DNA from over 100 pectoralis major muscle samples taken from individuals aged 18 to 85. They identified 20 DNA methylation sites, called CpGs, that were strongly associated with age. These CpGs were found in genes involved in muscle function, stress response, metabolism, and age-related diseases. Using these markers, the team built two machine learning models to predict age: one using Next-Generation Sequencing (NGS) and another using Single Base Extension (SBE). Both models were highly accurate, with average prediction errors between 3.8 and 5.5 years. The new “epigenetic clocks” outperformed existing age-prediction models designed for other tissue types. However, when applied to cardiac and uterine muscle, these models showed much lower accuracy, reinforcing the need for tissue-specific approaches in molecular age estimation. Beyond predicting age, the study also provides insight into how DNA methylation may affect muscle aging. Several of the identified CpGs were located in regions that regulate gene expression, being associated with a reduction of it in older muscle samples. Some of the affected genes are associated with sarcopenia, an age-related loss of muscle mass and strength. Overall, this study introduces two reliable and cost-effective methods to estimate age from skeletal muscle, even when the DNA is partially degraded, making it especially useful in forensic settings. It also offers a path forward for developing future therapies that may slow age-related muscle decline and highlights how skeletal muscle aging can differ depending on population, tissue type, and anatomical location. DOI - https://doi.org/10.18632/aging.206341 Corresponding author - Hwan Young Lee - hylee192@snu.ac.kr Abstract video - https://www.youtube.com/watch?v=1i6Ua0cceMU Sign up for free Altmetric alerts about this article - https://aging.altmetric.com/details/email_updates?id=10.18632%2Faging.206341 Subscribe for free publication alerts from Aging - https://www.aging-us.com/subscribe-to-toc-alerts Keywords - aging, skeletal muscle, age, DNA methylation, next generation sequencing, single base extension To learn more about the journal, please visit https://www.Aging-US.com​​ and connect with us on social media at: Bluesky - https://bsky.app/profile/aging-us.bsky.social ResearchGate - https://www.researchgate.net/journal/Aging-1945-4589 Facebook - https://www.facebook.com/AgingUS/ X - https://twitter.com/AgingJrnl Instagram - https://www.instagram.com/agingjrnl/ LinkedIn - https://www.linkedin.com/company/aging/ Reddit - https://www.reddit.com/user/AgingUS/ Pinterest - https://www.pinterest.com/AgingUS/ YouTube - https://www.youtube.com/@Aging-US Spotify - https://open.spotify.com/show/1X4HQQgegjReaf6Mozn6Mc MEDIA@IMPACTJOURNALS.COM

Okay you guys, this is a really weird episode to drop on a holiday: the latest chapter of Mayor of Kingstown (possibly the second-to-last episode ever?) bombarded us for 47 solid minutes with death, torture, plot twists, betrayal, and excrement MERRY CHRISTMAS. Seriously, this was hands down our favorite episode of the season, but maybe... The post Binary System Podcast #486 – Mayor of Kingstown season 4 episode 9 “Teeth and Tissue” first appeared on Pixelated Geek.

This episode originally broadcast on December 25, 2025. The original podcast post is here: https://pixelatedgeek.com/2025/12/binary-system-podcast-486-mayor-of-kingstown-season-4-episode-9-teeth-and-tissue/Okay you guys, this is a really weird episode to drop on a holiday: the latest chapter of Mayor of Kingstown (possibly the second-to-last episode ever?) bombarded us for 47 solid minutes with death, torture, plot twists, betrayal, and excrement MERRY CHRISTMAS.Seriously, this was hands down our favorite episode of the season, but maybe don't drink a cup of coffee before watching it, that's gotta be bad for your heart. One day we will stop using spinningmerkaba's Christmas On Mars as the outro at Christmas, but today is not…yeah, you know us better than that, we're never gonna stop using this.Here's our conversation about episode 8 we mentioned, giant GIANT spoiler warnings for that one.Looking for a present for that hard-to-shop-for person? Want to buy them (or yourself) a square foot of a castle in Scotland? Look no further! You can support the restoration of Dunan's castle, legally call yourself Lady or Laird, AND if you use this link to get there, you can support this podcast too! ScottishLaird.co.uk.For updates, fan art, and other randomness, come follow us on Facebook, Tumblr, Twitter, and Instagram!Buy us a coffee

Dr. Francis Marchlinski, Deputy Editor of JACC Clinical Electrophysiology, discusses Anatomy of the Isthmus: Unraveling the Tissue Composition of the Ventricular Tachycardia Diastolic Pathway.

All the guys are here to talk about this insane episode written by Hugh Dillon! Wow!Help Support The Podcast!Get ad–free pods and exclusive pods and an archive of all our pods at Patreon.com/DVRSubscribe to us and watch our pods on YOUTUBE! www.youtube.com/@dvrpodcastnetworkSubscribe to Daily DVRVisit us at DVRPodcast.comWe would love to hear from you! Email us at DVRPodcast@gmail.comWatch The Star City Murders on Tubi for FREE!Join our Facebook Group: https://www.facebook.com/groups/DailyDVRThanks to Dave for the music: https://invisibletoengines.bandcamp.com/releases Hosted on Acast. See acast.com/privacy for more information.

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Follow along as Donna and Sarah Jay break down Episode 5 of Project Runway Canada as the designers faced a "triple-decker" challenge: creating high-fashion looks from delicate Cashmere bathroom tissue, in just one day, while navigating a devious bait-and-switch that turned collaborative pairs into competitive duels.Donna and Sarah break down each designer's approach, the clever techniques designers used to master the fragile material, and the emotional bonds that form during the competition. They reflect on how the competition only gets tougher and the elimination of Delayne as the episode concludes with an interview from her.Links in this episode:Donna Bishop: @thisisdonnabSarah Jay: @sarahjaystyleFashionTalks: @fashiontalkspod | SubstackCAFA: cafawards.ca | @cafawards

First Human Cornea Transplant Using 3D Printed, Lab-Grown Tissue Restores Sight in a ‘Game Changer' for Millions Who are Blind Precise Bio completes 1st human cornea transplant using 3D-printed, lab-grown tissue Contact the Show: coolstuffdailypodcast@gmail.com Learn more about your ad choices. Visit megaphone.fm/adchoices

Day 7 of the Brian Walshe murder trial delivered the most damning forensic testimony yet. A Massachusetts State Police DNA analyst confirmed that Ana Walshe's genetic material was recovered from a piece of human tissue found in a dumpster near Brian's mother's apartment — the closest investigators have come to finding her remains nearly three years after her disappearance. But that wasn't all. Ana's DNA was also identified on a blood-stained hacksaw blade, a hatchet head, the handles of both tools, bloody towels, carpet fragments, and a clump of hair pulled from the same trash bags prosecutors say Brian Walshe used to dispose of his wife's body. The statistical probability? At least 30 nonillion times more likely to be Ana's DNA than an unknown person's. Several items also contained DNA from both Ana and Brian Walshe, including bloodstained slippers and a Tyvek suit. One item — gauze with a red-brown stain — matched Brian alone. Prosecutors had previously shown the jury a photo of a cut on his thumb. New surveillance footage showed Brian Walshe shopping at HomeGoods on January 2nd and 4th, 2023, buying rugs, towels, and bath mats — using store credit from his dead wife's previous returns. Prosecutors suggest he replaced the living room rug after Ana's death, pointing to photos showing a different carpet in the home when police searched it days later. The defense pushed back on cross-examination, arguing DNA testing can't determine when or how biological material was deposited and suggesting items may have cross-contaminated in the trash compactor. But prosecutors countered that cleaning products — including the hydrogen peroxide and ammonia Brian purchased on January 1st — can destroy blood evidence. Wednesday brings testimony from Gem Mutlu, Ana's former boss and the last person besides Brian known to have seen her alive. The prosecution may rest its case as early as tomorrow. #BrianWalshe #BrianWalsheTrial #AnaWalshe #TrueCrime #MurderTrial #CohassetMurder #DNAEvidence #TrueCrimeNews #MassachusettsCrime #JusticeForAna Want to comment and watch this podcast as a video? Check out our YouTube Channel. https://www.youtube.com/@hiddenkillerspod Instagram https://www.instagram.com/hiddenkillerspod/ Facebook https://www.facebook.com/hiddenkillerspod/ Tik-Tok https://www.tiktok.com/@hiddenkillerspod X Twitter https://x.com/tonybpod Listen Ad-Free On Apple Podcasts Here: https://podcasts.apple.com/us/podcast/true-crime-today-premium-plus-ad-free-advance-episode/id1705422872

Day 7 of the Brian Walshe murder trial delivered the most damning forensic testimony yet. A Massachusetts State Police DNA analyst confirmed that Ana Walshe's genetic material was recovered from a piece of human tissue found in a dumpster near Brian's mother's apartment — the closest investigators have come to finding her remains nearly three years after her disappearance. But that wasn't all. Ana's DNA was also identified on a blood-stained hacksaw blade, a hatchet head, the handles of both tools, bloody towels, carpet fragments, and a clump of hair pulled from the same trash bags prosecutors say Brian Walshe used to dispose of his wife's body. The statistical probability? At least 30 nonillion times more likely to be Ana's DNA than an unknown person's. Several items also contained DNA from both Ana and Brian Walshe, including bloodstained slippers and a Tyvek suit. One item — gauze with a red-brown stain — matched Brian alone. Prosecutors had previously shown the jury a photo of a cut on his thumb. New surveillance footage showed Brian Walshe shopping at HomeGoods on January 2nd and 4th, 2023, buying rugs, towels, and bath mats — using store credit from his dead wife's previous returns. Prosecutors suggest he replaced the living room rug after Ana's death, pointing to photos showing a different carpet in the home when police searched it days later. The defense pushed back on cross-examination, arguing DNA testing can't determine when or how biological material was deposited and suggesting items may have cross-contaminated in the trash compactor. But prosecutors countered that cleaning products — including the hydrogen peroxide and ammonia Brian purchased on January 1st — can destroy blood evidence. Wednesday brings testimony from Gem Mutlu, Ana's former boss and the last person besides Brian known to have seen her alive. The prosecution may rest its case as early as tomorrow. #BrianWalshe #BrianWalsheTrial #AnaWalshe #TrueCrime #MurderTrial #CohassetMurder #DNAEvidence #TrueCrimeNews #MassachusettsCrime #JusticeForAna Want to comment and watch this podcast as a video? Check out our YouTube Channel. https://www.youtube.com/@hiddenkillerspod Instagram https://www.instagram.com/hiddenkillerspod/ Facebook https://www.facebook.com/hiddenkillerspod/ Tik-Tok https://www.tiktok.com/@hiddenkillerspod X Twitter https://x.com/tonybpod Listen Ad-Free On Apple Podcasts Here: https://podcasts.apple.com/us/podcast/true-crime-today-premium-plus-ad-free-advance-episode/id1705422872

Arsenal 'Soft Tissue Specialist' Leaves Sparking Conspiracy, FA Cup, Club Brugge and Jesus Left Out

Title: Wheat Germ Agglutinin (WGA) Staining Optimized for Image Analysis of Muscle Tissue Morphometry  Authors: Cheru, R. and Wolf, J.C., Experimental Pathology Laboratories, Inc., Sterling, Virginia Abstract: Wheat Germ Agglutinin (WGA) is a plant-derived lectin and fluorescent stain that binds to N-acetylglucosamine and sialic acid residues in tissues, making it a valuable histochemical tool for visualizing cell membranes and components of the extracellular matrix. In muscle tissue, WGA staining allows clear delineation of the laminin-labeled basal membrane outlining each myofiber, distinguishing it from the residual autofluorescence of the myofiber sarcoplasm. To support digital pathology applications, a WGA staining protocol was optimized for compatibility with image-based quantitative analysis. Formalin-fixed, paraffin-embedded muscle sections were stained with fluorescently labeled WGA, counterstained with DAPI for nuclear visualization, and mounted with antifade medium to preserve fluorescence. Image analysis of WGA-stained skeletal muscle was successfully performed by a pathologist using Image-Pro® Plus software, employing macros to assess myofiber size and count.

Title: Employing Multi-Tissue Controls to Enhance Kidney Biopsy Protocol Education in a Program in Histotechnology Student Lab  Authors: Hyder Aljanabi, Damon Bendolph, Gabriella Casas, Yosan Embrafrash, Sara Hassan, Anastasja Kraft, Stephan Lloyd-Brown , Nida Mubeen, Minh Nguyen, Xena Orosco, Nicole Rivera, Moriam Sissoho, Tan Tang , Kaleena Ramirez, Toysha Mayer, Mark Bailey Abstract: In a Program in Histotechnology student laboratory, establishing a representative and clinical teaching laboratory environment is essential for preparing students to manage the complexities of diagnostic tissue processing. The objective of the project was to simulate real-world clinical procedures by integrating multi-tissue controls into student education competencies for kidney biopsy staining protocols. Students participated in the investigation, each receiving four pieces of formalin-fixed, paraffin-embedded (FFPE) tissue: kidney, liver, gastrointestinal tract (GI), and tonsil. The tissues served as controls to validate staining techniques commonly used in renal pathology. Students prepared tissue sections using a rotary microtome, sectioning tissue at four microns. In total, forty slides were prepared, with eighteen slides manually stained using specific histochemical methods. Stains included hematoxylin and eosin (H&E), periodic acid-Schiff (PAS), periodic acid methenamine silver (PAMS), and the Gomori Trichrome technique. The results yielded identifiable cellular and structural features critical for diagnostic interpretation. A slide review was conducted, and acceptable representative slides were selected for digital imaging. In addition, the results demonstrated the four tissue types which may be approved to use as controls, due to the consistency of demonstrating staining characteristics and features required for evaluating kidney biopsy protocols. Upon technical validation, the use of multi-tissue controls contributed to educational and operational outcomes. Students gained quality assurance experience, and the experience reinforced special stain and laboratory operations competencies, teaching students how to conserve reagent use, and to reduce time and expense. Furthermore, the protocol introduced the application of digital pathology and quality assurance in a real-world lab setting. Our investigation supports the integration of multi-tissue controls in histotechnology education as a valuable tool for enhancing both learning and laboratory efficiency. Future studies are recommended to include additional tissue types, stains, and immunohistochemical markers, to further advance and expand histotechnology educational competencies.

In this episode, Dr. Sparanese walks through a mysterious case defined by ongoing fevers, bowel issues, and an exhausting series of diagnostic tests and biopsies. Joined by Dr. Kassen, Dr. DaRoza, and Dr. Voyer, the group pieces through clues and theories in a collective attempt to identify an illness that remains stubbornly out of reach.

Send us a text Stop Starving Postpartum Mothers: The Dangerous Lie of the 300-500 Calorie Postpartum Diet RecommendationThe 300-500 calorie recommendation for breastfeeding?  It's fundamentally flawed, based on decades-old data scaled down from men, and is actively keeping postpartum mothers nutritionally depleted. Maranda is exposing this colossal gap in maternal health. Learn the real metabolic demands of healing, the truth about nutrient depletion, and the 1100–1600 extra calories needed for holistic recovery. This is the key to unlocking lasting solutions for your clients struggling with exhaustion and mood disorders.Check out this episode on the blog HERE: https://postpartumu.com/podcast/the-300-500-calorie-myth-why-standard-postpartum-nutrition-advice-is-starving-mothers-ep-244/Key time stamps: 02:12: Defining the 300-500 calorie myth and its inadequate nature.03:45: The shocking history: RDAs based on male bodies, not women.06:40: The massive nutrient depletion caused by pregnancy and birth.08:15: Milk production costs 500-700 calories—consuming the entire recommendation.09:30: Energetic demands: Tissue healing, blood rebuilding, hormone recalibration.10:18: The shocking truth: Moms need 1100–1600 extra calories a day.11:55: The focus of current science is accommodating weight loss, not healing.13:00: 80% of postpartum women are depleted in key nutrients.14:50: Why the body literally cannibalizes bones and teeth for milk.16:30: The solution: Focusing on nutrients, not just calories.17:00: Protein needed: 80 to 120 grams per day for tissue repair.17:55: Importance of therapeutic micronutrients (beyond RDA levels).18:40: The damaging effect of calorie restriction on postpartum hunger signals.19:50: Restricting calories triggers a stress response and leads to weight retention.20:45: The myth that breastfeeding guarantees automatic weight loss.21:40: Prolactin, the lactation hormone, triggers fat storage—it's protective.22:30: The 300-500 calorie recommendation needs to die.NEXT STEPS:

Program notes:0:40 CVD risk factors and texting1:40 How many undergo screening?2:41 Impact of personalized messaging3:25 Decentralized trials versus centralized 4:25 Decentralized much larger5:25 Does the trial move in one way or another?6:15 Two studies related to use of peripregnancy GLP-1 use7:15 Stopping at pregnancy8:15 Is overweight worse than stopping?9:00 Machine learning model, tissues, genetics and age10:00 Practical for assessing genetic basis11:00 Sequential tissue samples11:57 End

Today we spoke for a 2nd time to Dr. Larry Lytle who talked about how low level laser therapy can alter the body and what it actually does. According to the science the light waves from the Q-1000 laser restores electrons in the tissue. We lose electrons from the atoms within cells when we are […] The post Dr. Larry Lytle – How The Q-Laser Restores Electrons To Atoms Changing Tissue PH & Ultimately Supercharges Your Health appeared first on Extreme Health Radio.

FFoDpod.com   Patreon   Merchandise   CC-BY-SA  "SCP-651" by psh, from the SCP Wiki. Source: https://scpwiki.com/scp-651. Licensed under CC BY-SA.

Takeaways:Drug transfer during lactation is complex and challenging.Semaglutide was not detected in women taking any dose.Low amounts of tears epitide were found in milk.Tissue damage can affect drug absorption.Mastitis and engorgement complicate the lactation process.Injections are necessary for effective drug delivery.The analogy of an elephant illustrates the difficulty of drug transfer.Detection of drugs in milk is a critical concern for breastfeeding mothers.Understanding turnover is essential in lactation studies.The implications of drug transfer on women's health are significant.Infant Risk Center Link  Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

In this episode, the hosts discuss the nuances of artificial intelligence and machine learning, exploring its implications for the job market and human performance. They delve into the limitations of AI, particularly in creative and nuanced tasks, and examine the impact of social media on perception and engagement. The conversation emphasizes the importance of authenticity in branding, the balance between innovation and execution in business, and the value of life experience in shaping career paths. Ultimately, the discussion highlights the need for transparency and authenticity in content creation and branding strategies.

This week we crack open the newly remastered Frankenstein, starring Jacob Elordi, Oscar Isaac, Mia Goth, and Christoph Waltz. Victor Frankenstein, science's most dramatic overachiever, creates a creature, chaos ensues, and everyone could really use a therapist.Visually? Stunning. A full gothic buffet of moody sets, lush costumes, and “should I move into this castle?” vibes.But is this two-hour monster saga worth your precious streaming time? Spoiler: Yes. And trust us, we have thoughts… plenty of them. Tune in for all the beauty, the mess, and the “Victor, please stop touching things” energy.

If intimacy has begun to feel painful, tense, or something you avoid… this episode will help you exhale. Painful sex isn't "in your head." It's not stress. And it's absolutely not something you're meant to live with. It's a message from your body — a message you can respond to and heal. Dr. Andrea McSwain unpacks the real physiology behind: • Burning, stinging, dryness, or tearing • Postpartum discomfort • Hormone-related tissue thinning • Pelvic floor tension • Microbiome disruption • Fear-brain anticipation cycles • Low libido from stress or birth control • When PRP vaginal rejuvenation can help You'll walk away with science, clarity, and practical steps you can apply today — all delivered in Dr. McSwain's warm, validating, and deeply human teaching style. If you remember only one thing: Your body is not broken. It's communicating. And with the right support, it can absolutely heal. Perfect for anyone navigating: • Painful intercourse • Hormone imbalance • Perimenopause changes • Stress-related libido loss • Pelvic floor dysfunction • Tissue scarring or dryness • Postpartum healing Whatever you're facing, you're not alone — and you're closer to relief than you think.  

Tissue regeneration isn't out of earshot!

Many women think implants are the only way to get fuller, perkier breasts, but there's another option. Breast lift with auto-augmentation uses your own natural tissue to restore shape and lift, no implants needed.San Diego plastic surgeon Dr. Luke Swistun explains how this underused technique works, who it's best for, and how his patients feel about their results so far. By reshaping and “restacking” existing tissue, he creates long-lasting, natural results that look and feel completely your own.He also shares how auto-augmentation can improve symmetry, simplify recovery, and align with today's trend toward natural, athletic results. LinksLearn more about breast liftRead more about San Diego plastic surgeon Dr. Luke SwistunBook a free 15-to-30-minute complimentary phone call with Dr. Swistun's patient coordinatorLearn from the talented plastic surgeons inside La Jolla Cosmetic Surgery Centre, the 12x winner of the San Diego's Best Union-Tribune Readers Poll, global winner of the 2020 MyFaceMyBody Best Cosmetic/Plastic Surgery Practice, and the 2025 winner of Best Cosmetic Surgery Group in San Diego Magazine's Best of San Diego Awards.Join hostess Monique Ramsey as she takes you inside LJCSC, where dreams become real. Featuring the unique expertise of San Diego's most loved plastic surgeons, this podcast covers the latest trends in aesthetic surgery, including breast augmentation, breast implant removal, tummy tuck, mommy makeover, labiaplasty, facelifts and rhinoplasty.La Jolla Cosmetic Surgery Centre is located just off the I-5 San Diego Freeway at 9850 Genesee Ave, Suite 130 in the Ximed building on the Scripps Memorial Hospital campus.To learn more, go to LJCSC.com or follow the team on Instagram @LJCSCWatch the LJCSC Dream Team on YouTube @LaJollaCosmeticSurgeryCentreThe La Jolla Cosmetic Surgery Podcast is a production of The Axis: theaxis.io Theme music: Busy People, SOOP

This episode of TTCL will feature an interview with Luis Santiago from NFH on La Mega. This monthly interview will inform the Spanish Community about Network For Hope and the incredible miracles that happen with Organ, Tissue, and Eye Donation. Resources: https://getoffthelist.org/ https://www.networkforhope.org/ https://www.networkforhope.org/about-us/ https://www.facebook.com/NetworkForHopeOPO https://aopo.org/ RegisterMe.org/NetworkforHope

Danny kicks off a brand new week of Yesterday's Quiz, Callum Leslie joins in with The Surname Game and there's Lorde news in All The Latest Things! Plus, Greg catches wind of a cover up job as Kieran asks Is It Just Us?

Hosts Zach and Kevin put the sports talk (mostly) aside to dive deep into a critical area of everyday dentistry: various scenarios involving soft and hard tissue grafting and the management of periodontal recession. They discuss how to handle common cases like recession in post-ortho teens (especially on the lower anterior teeth) and the different approaches for the challenging chewing tobacco patient. Zach and Kevin share their experience with generalized recession, debating when to refer for a graft—often noting that patient concern over esthetics or sensitivity drives the decision more than the presence of the recession itself. The conversation covers treatment techniques like free gingival grafts and the status of fads like the LANAP procedure and pinhole technique. They also explore other periodontal topics, including the management of gingival overgrowth (gummy smiles), peri-implantitis complications, and their skepticism regarding the widespread use of local antimicrobial delivery systems (like Arrestin) for routine scaling and root planing cases. Tune in for a candid discussion on what's working (and what's not) in the everyday management of periodontal health in a general practice. Join the Very Clinical Facebook group!  Join the Very Dental Facebook group using the password "Timmerman," "Bioclear," "Hornbrook," McWethy," "Papa Randy," "Lipscomb" or "Gary!" The Very Dental Podcast network is and will remain free to download. If you'd like to support the shows you love at Very Dental then show a little love to the people that support us! -- Crazy Dental has everything you need from cotton rolls to equipment and everything in between and the best prices you'll find anywhere! If you head over to verydentalpodcast.com/crazy and use coupon code "VERYDENTAL10" you'll get another 10% off your order! Go save yourself some money and support the show all at the same time! -- The Wonderist Agency is basically a one stop shop for marketing your practice and your brand. From logo redesign to a full service marketing plan, the folks at Wonderist have you covered! Go check them out at verydentalpodcast.com/wonderist! -- Enova Illumination makes the very best in loupes and headlights, including their new ergonomic angled prism loupes! They also distribute loupe mounted cameras and even the amazing line of Zumax microscopes! If you want to help out the podcast while upping your magnification and headlight game, you need to head over to verydentalpodcast.com/enova to see their whole line of products! -- CAD-Ray offers the best service on a wide variety of digital scanners, printers, mills and even  their very own browser based design software, Clinux! CAD-Ray has been a huge supporter of the Very Dental Podcast Network and I can tell you that you'll get no better service on everything digital dentistry than the folks from CAD-Ray. Go check them out at verydentalpodcast.com/CADRay!  

The Man Behind Cannabis Tissue Culture Labs

Did you know that nearly all embryos show some level of mosaicism, even in successful pregnancies? In this conversation with Meaghan Doyle, a Licensed Certified Genetic Counselor specializing in fertility genetics and the founder of DNAide Genetic Counseling, we're discussing the latest findings on PGT-A testing and what it means for embryo selection and fertility treatment: and this is fascinating! Meaghan joins me to discuss a fascinating new article titled "New PGT-A Test Shows that Nearly All Blastocysts and Fetal Tissue are Mosaic." We'll break down what this means for fertility treatment, embryo selection, and how patients can use this information to make the best decisions for their family-building journey. In this episode, we cover: What PGT-A testing does and how its sensitivity has evolved What mosaicism is and why nearly all embryos exhibit it How new research is changing the way we interpret mosaic results What these findings mean for embryo selection and transfer decisions How fertility patients can advocate for themselves and make informed choices Resources Find Meaghan Doyle's DNAide Genetic Counseling website here Follow Meaghan on Instagram Join The IVF Class Find Dr. Aimee's Fertility Essentials & Supplements Do you have questions about IVF?Click here to join Dr. Aimee for The IVF Class. The next live class call is on Monday, November 17, 2025 at 4pm PST, where Dr. Aimee will explain IVF and there will be time to ask her your questions live on Zoom.   Dr. Aimee Eyvazzadeh is one of America's most well known fertility doctors. Her success rate at baby-making is what gives future parents hope when all hope is lost. She pioneered the TUSHY Method and BALLS Method to decrease your time to pregnancy. Learn more about the TUSHY Method and find a wealth of fertility resources at www.draimee.org. Other ways to connect with Dr. Aimee and The Egg Whisperer Show: Subscribe to my YouTube channel for more fertility tips!Subscribe to the newsletter to get updates

In this episode, we feature some of the winners of poster and oral presentation competitions at the 2025 ADSA Annual Meeting in Louisville, Kentucky. Abstracts can be found here: ADSA 2025 Annual MeetingMS Oral Presentation, ProductionGuests: Trinidad Fernandez-Wallace and Dr. Lautaro Rostoll-Cangiano, University of Wisconsin-MadisonCo-host: Dr. Laura Niehues, BalchemAbstract 1218: Immunity at the crossroads of cellular metabolism: Navigating T helper shifts in the periparturient period of dairy cows. (0:08)Trinidad found that T-helper cell metabolism and proliferation were both upregulated after calving, which may impact the effectiveness of immune responses during the transition period. The group discusses if T-helper cells could be used as a marker of inflammation in the future and how Trinidad's results may have been different if samples had been collected between 3 and 28 days after calving.PhD Oral Presentation, ProductionGuests: Natnicha Taechachokevivat and Dr. Rafael Neves, Purdue UniversityCo-host: Dr. Sion Richards, Balchem Abstract 1107: Relationships between systemic inflammation, subclinical hypocalcemia, and hyperketonemia in clinically healthy Holstein cows. (8:07)Natnicha investigated the association of plasma haptoglobin (an inflammatory marker) on days 1 and 3 in milk with subclinical hypocalcemia and hyperketonemia. Systemic inflammation appears to be associated with subclinical hypocalcemia and hyperketonemia and reduced milk yield in multiparous cows. When multiparous cows exhibited both inflammation and metabolic disease indicators, they produced less milk; however, when primiparous cows exhibited both inflammation and metabolic disease indicators, they produced more milk. 3 Minute ThesisGuests: Savitha Saikumar and Dr. Diwaker Vyas, University of FloridaCo-host: Dr. Laura Niehues, BalchemAbstract 1548: Effects of peripartal supplementation of prototype postbiotics on intake, rumen fermentation, colostrum quality, and performance in transition dairy cows. (15:14)Savitha investigated the effects of a prototype postbiotic supplement in transition cows from 35 days before calving to 63 days after calving. Cows on the postbiotic treatment received 25 grams per day topdressed on their TMR. Before calving, the postbiotic had no effect on dry matter intake, body condition sore, body weight, or total VFAs. After calving, the postbiotic increased dry matter intake and milk yield after 6 weeks, and increased energy-corrected milk and fat-corrected milk with no effect on body weight, body condition score, or rumen fermentation profile.PhD Poster Guest: Amanda Fischer-Tlustos, University of Guelph Abstract 2012: Characterization of dry-period mammary acetate and glucose metabolism and their association with colostrum production in multiparous Holstein cattle. (25:15)Amanda's research evaluated acetate and glucose metabolism in the mammary gland during the dry and calving periods to better understand how colostrum is made. Acetate uptake by the udder remained fairly constant until one week before calving, when it started to increase. Glucose uptake did not increase until the onset of calving. Previous lactation milk production and far-off mammary metabolism were both negatively correlated with colostrum production. Amanda hypothesizes that high producing cows who have trouble drying off may have high amounts of metabolic activity in the mammary gland when they should have low activity, which may result in lower colostrum production at the subsequent calving. PhD Oral Presentation, Southern Branch DivisionGuests: Bridger Sparks and Dr. Clarissa Strieder-Barboza, Texas Tech UniversityCo-host: Dr. Ryan Pralle, BalchemAbstract 1215: Adipose tissue neuro-like cell profile changes with ketosis in dairy cows. (33:05)Bridger investigated neuro-like cells in the adipose tissue of cows with or without subclinical ketosis. The transcriptional profile of neuro-like cells changed when collected from cows with subclinical ketosis, which may indicate a potential regulatory role in adipose tissue metabolism. Perhaps modulation of neuro-like cells could potentially alleviate excessive adipose mobilization in the postpartum period. ADSA Graduate Student Division HighlightsGuests: Evelyn Yufeng Lin, North Carolina State University; Miranda Farricker, Cornell University; Conor McCabe, University of California-Davis; Dr. Maurice Eastridge, Ohio State University. (40:45) Dr. Eastridge is the chair of the ADSA Foundation and explains some of the Foundation's current projects. Evelyn and Conor are past presidents of the ADSA Graduate Student Division, and Miranda is the incoming president. Each student gives a bit of background on themselves and their research and describes what the Graduate Student Division does and how they foster new graduate students in ADSA.  Please subscribe and share with your industry friends to invite more people to join us at the Real Science Exchange virtual pub table.  If you want one of our Real Science Exchange t-shirts, screenshot your rating, review, or subscription, and email a picture to anh.marketing@balchem.com. Include your size and mailing address, and we'll mail you a shirt.

Dr. Arun Sharma Monday 10-27-25 Space ShowQuick Summary:Our program focused on the establishment and operations of Cedars-Sinai's new Space Medicine Research Center, including its research programs, educational components, and institutional support. Arun discussed their stem cell research initiatives, particularly the creation of 3D heart tissue organoids grown in microgravity on the ISS, and explained their approach to training astronauts and conducting space-based medical research. The conversation covered the potential of AI and telemedicine in space missions, regulatory challenges in stem cell research, and the future opportunities presented by commercial space stations for conducting biomedical research. David and Arun were joined by participant Dr. Sherry Bell.Detailed Summary:David and Dr. Sherry Bell discussed the establishment of the Center for Space Medicine Research at Cedars-Sinai, led by Arun. Arun confirmed the center's functionality and its institutional support, emphasizing its research and educational components. After Arun was welcomed back to The Space Show to discuss Cedars-Sinai Medical Center's new Space Medicine Research Center. Arun explained that the center, established about a year ago, builds on their 10 years of work in stem cell and biomanufacturing research, including 8 missions to the ISS. He noted that the center has both research and educational components, offering courses in space medicine and biosciences as part of their master's and PhD programs. Arun emphasized their institutional support and goal to become an academic partner for the growing private space industry in Los Angeles.Arun discussed Cedars' expansion beyond cardiovascular focus to broader biomanufacturing and space research, with plans to establish a clinical arm leveraging their hospital's expertise. He mentioned ongoing conversations with local space industry players in LA, though details are not yet public. Arun also outlined their vision for a comprehensive space medicine program, including pre-flight workups, in-flight diagnostics, and post-flight checkups, while acknowledging the need for space medical training for their network of providers.Arun further discussed his research on 3D heart tissue, or cardiac organoids, created from induced pluripotent stem cells (iPSCs). He explained that these tissues are grown in microgravity on the ISS, as microgravity may improve their growth compared to simulated microgravity on Earth. Arun clarified that the iPSCs and necessary chemicals were launched on SpaceX 33 in August and are now orbiting Earth. David inquired about astronaut training, and Arun explained that they work with engineers and partners like BioServe Space Technologies to train astronauts, as most are not life scientists. Arun expressed a desire for more direct communication with astronauts in the future.The discussion then focused on stem cell research and space medicine training. Arun explained that stem cells are sourced from de-identified donor samples at Cedars-Sinai, with consent for medical research use. The long-term goal is to create patient-specific bioengineered organs, starting with heart tissues, though this remains an area of ongoing research. Arun clarified that the initial training program will focus on biosciences for research scientists, with plans to expand to clinical training in the future.Arun did talk about the potential of AI and telemedicine in supporting deep space missions, emphasizing the value of human-focused research over animal studies. He clarified that his lab uses patient-specific stem cell models, focusing on human biology, and does not work with embryonic stem cells. Arun also addressed the cost and funding challenges of conducting research in space, mentioning partnerships with government agencies and the need to explore alternative funding sources for future collaborations. David inquired about simulating microgravity studies, to which Arun explained that while some ground-based simulations exist, they do not perfectly replicate the conditions of true space microgravity.Arun explained that the stem cell research at Cedars Space Lab involves creating three-dimensional organoids to study human biology and potentially identify new drugs, but emphasized that these cells cannot be transplanted back into people due to ethical and regulatory constraints. He clarified that the research is outcome-oriented, focusing on whether stem cells can be improved in space, with the goal of creating better models for understanding heart development and drug efficacy. David raised concerns about potential regulatory differences between countries, particularly regarding stem cell research, and Arun acknowledged that while the US has strict guidelines, some international research may go unpublished, making it difficult to track all ongoing work in this field.Arun discussed his work as a stem cell biologist and highlighted the potential of space biology research, mentioning a recent publication by UC San Diego on growing cancer cells in space. He expressed concerns about the transition from the ISS to commercial space stations, acknowledging the ISS's valuable contributions to research but seeing an opportunity for the commercial industry to fill the gap. Arun also considered the possibility of conducting research on a commercial space station, emphasizing the potential for more biomedical researchers in space and the possibility of accelerated training in a private space capacity. He expressed interest in the idea of conducting his own research on a private space station, such as SpaceX's Starship, and noted the importance of access and opportunities for further research.Arun discussed the differences between microgravity and partial gravity environments in space, highlighting the potential for developing unique therapeutic options that may only be applicable in space. He explained that while some treatments could be brought back to Earth, others might require patients to travel to space for treatment. Arun also touched on the current state of stem cell research, including clinical trials for various applications, and expressed optimism about future advancements in bioprinting and organoid manufacturing in space. He emphasized the importance of personalized medicine using patient-specific stem cells and encouraged continued interest in both stem cell and space biology research.Be sure to see the video of this program at doctorspace.substack.com.Special thanks to our sponsors:Northrup Grumman, American Institute of Aeronautics and Astronautics, Helix Space in Luxembourg, Celestis Memorial Spaceflights, Astrox Corporation, Dr. Haym Benaroya of Rutgers University, The Space Settlement Progress Blog by John Jossy, The Atlantis Project, and Artless EntertainmentOur Toll Free Line for Live Broadcasts: 1-866-687-7223 (Not in service at this time)For real time program participation, email Dr. Space at: drspace@thespaceshow.com for instructions and access.The Space Show is a non-profit 501C3 through its parent, One Giant Leap Foundation, Inc. To donate via Pay Pal, use:To donate with Zelle, use the email address: david@onegiantleapfoundation.org.If you prefer donating with a check, please make the check payable to One Giant Leap Foundation and mail to:One Giant Leap Foundation, 11035 Lavender Hill Drive Ste. 160-306 Las Vegas, NV 89135Upcoming Programs:Broadcast 4455 ZOOM: Arkisys CEO David Barnhart | Sunday 02 Nov 2025 1200PM PTGuests:ZOOM, Dave Barnhart, CEO of Arkisys updates us with interesting news and developments Get full access to The Space Show-One Giant Leap Foundation at doctorspace.substack.com/subscribe

Do you have dense breasts? Are mammograms always the best option? How can thermography support breast and whole body health? With so much interest in our recent coverage of thermography, this follow-up conversation dug even deeper into the topic with Patricia Bowden Luccardi, CTT, CNMT, LMT. We explore the role of thermography as a tool for breast health monitoring, the risks and considerations tied to mammograms, and special concerns for women with dense or fibrocystic breasts. You will gain a deeper understanding of how different screening methods compare and what proactive steps you can take to better support long-term breast health. Plus learn why wearing a bra might be bad for your breasts, the connection between oral and breast health, and how caffeine can drive excessive estrogen in this jam packed episode!  More about Patricia:  Having studied and taught a variety of natural health modalities and therapies, Patricia Bowden-Luccardi has been a lifetime student of integrative health and wellness.  For over 25 years she has been teaching and providing private consultations on health protocols customized to her clientele's personal needs.    During the past thirteen years, Patricia has focused her expertise on the natural prevention of breast cancer. She is a professional advocate and practitioner for the promotion of radiation-free thermography.    Her public seminars and lectures are designed to educate women about the serious health risks of environmental toxins, endocrine disruptors, and breast cancer. Her natural protocols including diet, plant-based supplementation and lifestyle changes have revealed extraordinary results that have been later visibly confirmed by thermographic imaging.  Patricia holds licensed certifications in Thermographic Technology, Clinical Massage Therapy, Food as Medicine, and Whole Health Education and lifestyle and wellness coaching. A member of Professional Academy of Clinical Thermology She authored the book Thermography and the Fibrocystic and Dense Breast, a Radiation-Free Guide to Happy Healthy Breasts.   Where to find more about Patricia Luccardi: Thermography and the Fibrocystic and Dense Breast / A Radiation-Free Guide to Happy Healthy Breasts www.patricialuccardi.com Breast Thermography International www.btiscan.com   Also in this episode:  Patricia's Story What is Thermography Episode 446 Thermography as an Assessment of Wellness  How Sulforaphane can support Breast Health BroccoDetox Thermography vs. Mammogram for Dense Breasts Effectiveness of a noninvasive digital infrared thermal imaging system in the detection of breast cancer Mammography screening does not save lives or breasts | The BMJ Cumulative effects of radiation Naturally Nourished Episode 188 Body Autonomy and Listening to Your Inner Wisdom with Dr. Christiane Northrup Alternatives for dense breasts HER Scan QT Scan  Dr. Jean Simmons Oral health and breast health Naturally Nourished Episode 370 Biological Dentistry with Dr. Joan Sefcik Bras and restrictive clothing Dressed to Kill - Sydney Singer Caffeine and estrogen Lymphatic Drainage and movement Sauna - we love Sunlighten Sauna use code ALIMILLERRD The role of iodine in breast health Naturally Nourished Episode 457 All About Iodine Lugol's iodine with castor oil for breast massage Hakala labs iodine test Supplements for breast health Plant stem cells nature-provides.com Cellular Antiox AHCC medicinal mushrooms Vitamin D  Vitamin D Blood Spot Test Vitamin D Balanced Blend Dairy and estrogen dominance Success stories Lymph star machine Boobs: The War on Breasts CNB Breast Oil Queen of Thrones Castor Oil Packs   Sponsor for this episode:  This episode is sponsored by Air Doctor.  The indoor air that we breathe can be up to 100 times  MORE polluted than outdoor air, according to the EPA. Indoor air pollutants can cause respiratory symptoms like sneezing, congestion, scratchy throat, and even more serious health problems like lung and heart disease. Introducing AirDoctor, the air purifier that filters out 99.99% of dangerous contaminants so your lungs don't have to. This includes allergens, pollen, pet dander, dust mites, mold spores and even bacteria and viruses.AirDoctor comes with a 30-day money back guarantee so if you don't love it, just send it back for a refund, minus shipping!Head to airdoctorpro.com and use promo code ALIMILLERRD and you'll receive UP TO $300 off air purifiers! Exclusive to podcast customers, you will also receive a free 3 year warranty on any unit, which is an additional $84 value!