Podcasts about Tissue

In this episode of the Beauty and the Beast podcast, Ross and I  delve into the intricacies of periodized training, exploring its relevance in both rehabilitation and performance contexts. Discussing the evolution of training methods, the importance of managing stress and recovery, and the significance of tissue healing in rehabilitation. Touching on pain management, client mindsets, and the necessity of movement during recovery.We provided insights on exercise variation, the balance between strength and endurance, and practical advice for determining appropriate weights. TakeawaysPeriodization training is essential for both rehab and performance.Managing stress and recovery is crucial in training.Tissue healing should guide rehabilitation strategies.Pain management requires a nuanced approach.Movement is vital for recovery, even with injuries.Client expectations can impact recovery outcomes.Common sense plays a key role in training decisions.Behavior change is necessary for effective rehabilitation.Exercise variation can prevent boredom and enhance engagement.Maintaining strength during endurance training is important.00:00 Reconnecting and Setting the Stage02:57 Understanding Periodization in Training05:57 The Evolution of Training Approaches08:43 Managing Volume and Intensity in Training12:00 Navigating Pain and Injury in Training14:57 Behavior Change and Patient Education18:04 The Role of Fear in Recovery20:40 Collaborative Approaches to Rehabilitation23:53 The Importance of Individualized Care30:48 The Importance of Exercise Variation in Training32:51 Maximizing Workout Efficiency: Quality Over Quantity35:46 Understanding Periodization in Strength and Endurance Training38:44 The Ebb and Flow of Training: Balancing Strength and Endurance44:50 Implementing a Simple Periodization Plan56:33 The Role of Professional Guidance in Training

Danny and Chris - Performance Therapists - join us (in-person) for 111th episode of MTN. On this episode of the podcast, we have a roundtable discussion on all things Tissue Tolerance related. Chris and Danny (both returning guests on the podcast), dive into the way that their minds break down movement, return to play, and much much more. With some incredible case studies and a conversation that has a lot of left turns, this was one that you won't want to miss.Catch Chris on IG @chrisguarin_ and Danny on IG @danmode_ruderockFind and follow us on social media @mtn_perform and check back each Wednesday for a new episodeBig Thanks to our sponsor Lumin Sports:Lumin continues to change the game within the AMS realm and recently launched their new strength builder platform. Head on over to luminsports.com - and mention Move the Needle at Check out to receive 20% off your first full year.& a huge Thank You to our sponsor, Hawkin Dynamics: Hawkin is the world leader in force measuring, and continues to put forth the tools for high-performance practitioners to be exactly that, high performers. If you haven't yet checked out Hawkins - head over to their website at: https://www.hawkindynamics.com/ and check out everything they have to offerMake sure to check out our sponsor, Samson Equipment: Samson is a leader in manufacturing elite weight room equipment (and have been for nearly 50 years). Founded by Dave and Linda Schroeder, Samson is weight room equipment made by coaches for coaches. Check them out at samsonequipment.com for more informationShoutout to our sponsor, 1080 Motion. The 1080 Sprint is the single best piece of training equipment in the world & has continually changed the game for training speed, strength, and power. Go to 1080motion.com to learn more.

The daily challenges and emotional toll of living with dense breast tissue and a heightened risk of breast cancer: Host Lisa Malia sat down with guest Caitlin Moyer to discuss a subject often overlooked.   Through Caitlin's candid narrative, listeners gain a window into the multi-layered journey many women face—from confusing mammogram results and insurance battles to the importance of building networks of support and advocating for oneself in a complicated medical system.   Stories like Caitlin's aren't just personal; they're powerful tools for education and community. A significant turning point in Caitlin's journey was realizing the crucial role of self-advocacy—especially when faced with conflicting or careless advice. She trusted her instincts, questioned the guidance, and ultimately chose to find a new gynecologist who aligned better with her needs.   Timestamps:    00:00 Caitlin Moyer's Breast Health Journey   05:29 Gynecologist's Troublesome Mammogram Recommendaition   09:00 "Advocacy and Proactive Healthcare"   10:22 Mammogram Controversy with OB GYN   15:04 Considering Preventive Mastectomy   16:38 Dense Tissue & Mastectomy Decision   21:29 Advocating for Necessary Healthcare Access   25:18 "Share Your Story Openly"   27:58 Genetic Risk and Double Mastectomy   30:10 Gratitude for conversation   Learn more about The Clear Pathways Program, Walk, Summit, App and Initiative powered by For The Love Of Cups and join our task force or advisory board: https://www.breastdensitysummit.org/   Caitlin Moyer is a passionate writer and storyteller who runs her own communications and marketing consulting agency, specializing in creative strategy, public relations, and social media. Before launching her business, Caitlin spent 18 seasons with the Milwaukee Brewers, where she founded the team's New Media department and led social media strategy, helping the Brewers become a leader in fan engagement. Her diverse client roster spans sports and beyond, including PGA Tour events, the Green Bay Packers, Indiana Pacers, U.S. Speedskating, and the Wisconsin State Golf Association.   Caitlin also serves as an adjunct professor at Marquette University, where she teaches an emerging media class. Deeply committed to golf and fitness, Caitlin is a registered yoga teacher and a NASM-certified personal trainer with a specialization in golf fitness. Most mornings, before working with her business clients, she can be found in the gym or studio leading group classes or one-on-one sessions. In her free time, she enjoys playing golf, running, and practicing yoga.   Website: https://www.CaitlinMoyer.com Instagram: / caitlinmoyer       #densebreast #breastmri #breastdensity #nonprofitleadership

Send us a textHave you ever wondered exactly how much lavage solution is needed to effectively decontaminate a surgical wound? This question, so common in veterinary operating rooms, finally has an evidence-based answer.Dr. Vanna Dickerson and veterinary student Cody Westmoreland from Texas A&M University join us to discuss their groundbreaking research on subcutaneous tissue lavage. Their study, published in the American Journal of Veterinary Research, reveals that using just 2.5 milliliters of sterile saline per centimeter of incision length can significantly reduce bacterial counts below infection-causing thresholds. This finding challenges previous assumptions and provides surgeons with a practical reference point for clinical decision-making.The conversation explores the persistent challenge of surgical site infections, which affect 7-10% of patients following GI surgery despite our best preventive efforts. Dr. Dickerson shares her surprise at discovering that relatively modest lavage volumes produced significant bacterial reduction in their silicone model, though she suggests using approximately 10 mL per centimeter in clinical practice to account for the complexities of living tissue. Westmoreland, who brought his experience in surgical infection prevention to this veterinary student research project, discusses plans for future clinical validation studies and potential applications of artificial intelligence in wound management.Beyond the science, we delve into the researchers' backgrounds, including Westmoreland's journey from operating room technician to veterinary student and Dr. Dickerson's collection of office dinosaurs that "make it impossible to have a bad day." Their work exemplifies how relatively simple interventions can significantly impact patient outcomes and client financial burden in veterinary practice.Listen now to discover how this easy, inexpensive technique might improve your surgical outcomes, and don't forget to leave us a rating and review on your favorite podcast platform!Open access article: https://doi.org/10.2460/ajvr.25.01.0030INTERESTED IN SUBMITTING YOUR MANUSCRIPT TO JAVMA ® OR AJVR ® ? JAVMA ® : https://avma.org/JAVMAAuthors AJVR ® : https://avma.org/AJVRAuthorsFOLLOW US:JAVMA ® : Facebook: Journal of the American Veterinary Medical Association - JAVMA | Facebook Instagram: JAVMA (@avma_javma) • Instagram photos and videos Twitter: JAVMA (@AVMAJAVMA) / Twitter AJVR ® : Facebook: American Journal of Veterinary Research - AJVR | Facebook Instagram: AJVR (@ajvroa) • Instagram photos and videos Twitter: AJVR (@AJVROA) / Twitter JAVMA ® and AJVR ® LinkedIn: https://linkedin.com/company/avma-journals

 New liquid metal-infused circuit boards can self-heal and work after taking heavy damageSource: LiveScience.comLink: https://www.livescience.com/technology/electronics/unlike-conventional-electronics-liquid-metal-used-in-novel-circuit-boards-can-self-heal-and-work-after-taking-heavy-damageStory 2: Cooling data centers is a multi-billion-dollar problem - now researchers want to use a common cooling mechanism found in animals to solve itSource: TechRadar.comLink: https://www.techradar.com/pro/cooling-data-centers-is-a-multi-billion-dollar-problem-researchers-want-to-use-a-common-cooling-mechanism-found-in-animals-to-solve-that-issueSee research paper here: https://www.cell.com/joule/abstract/S2542-4351(25)00156-4?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS2542435125001564%3Fshowall%3DtrueStory 3: Scientists invent weird, shape-shifting 'electronic ink' that could give rise to a new generation of flexible gadgetsSource: LiveScience.comLink: https://www.msn.com/en-us/news/technology/scientists-invent-weird-shape-shifting-electronic-ink-that-could-give-rise-to-a-new-generation-of-flexible-gadgets/ar-AA1HAE0vStory 4: A bionic knee integrated into tissue can restore natural movementSource: MIT NewsLink: https://news.mit.edu/2025/bionic-knee-integrated-into-tissue-can-restore-natural-movement-0710See research paper “Tissue-integrated bionic knee restores versatile legged movement after amputation” here: https://www.science.org/doi/10.1126/science.adv3223Honorable MentionsStory: Using AI to make lower-carbon, faster-curing concreteSource: Engineering at MetaLink: https://engineering.fb.com/2025/07/16/data-center-engineering/ai-make-lower-carbon-faster-curing-concrete/Story: A mild spinal zap can cut brain-computer interface learning time in halfSource: Medicine.netLink: https://www.medicine.net/news/Neurology/A-mild-spinal-zap-can-cut-brain-computer-interface-learning-time-in-half.htmlStory: Scientists invent photosynthetic 'living' material that sucks CO2 out of the atmosphereSource: LiveScience.comLink: https://www.livescience.com/technology/engineering/scientists-invent-photosynthetic-living-material-that-sucks-co2-out-of-the-atmosphereStory: Alzheimer's gene therapy shows promise in preserving cognitive functionSource: University of California San DiegoLink: https://www.universityofcalifornia.edu/news/alzheimers-gene-therapy-shows-promise-preserving-cognitive-function

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Raspberry Buttholes. Shipping George Lucas Overseas. Grandma's soap taste. Even More Ivan-Hoes. Man of Steel, Woman of Tissue. I don't like wasps eeeeeeiiiiiiiiiiither! Hollywood Accounting 101 with Stephen and more on this episode of The Morning Stream. Hosted on Acast. See acast.com/privacy for more information.

Raspberry Buttholes. Shipping George Lucas Overseas. Grandma's soap taste. Even More Ivan-Hoes. Man of Steel, Woman of Tissue. I don't like wasps eeeeeeiiiiiiiiiiither! Hollywood Accounting 101 with Stephen and more on this episode of The Morning Stream. Hosted on Acast. See acast.com/privacy for more information.

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Pterosaur soft tissues It's a double new paper episode this time as thanks to the magic of almost random review and publication times, Dave has two papers out on the same subject in the same month! So strap in for some absolute minutiae on pterosaur hands, feet, scales, and the oddly overlooked wing membrane that sits between their legs. Pterosaurs in general are not very common fossils and so it should be no surprise that we don't have a great many examples of their soft tissues, from skin, to beaks and claws and other bits. So, having new examples, and synthesising the limited information we have, is really important for building an understanding of these incredible animals. It's deep dive time.       A link to Dave's blogpost on the new hand and foot scale papers: https://archosaurmusings.wordpress.com/2025/06/10/new-data-on-pterosaurian-soft-tissues/   A link to a very old blogpost about pterosaur soft tissues generally: https://archosaurmusings.wordpress.com/2008/07/25/pterosaur-soft-tissues/   Iszi'a new book - featuring a pterosaur and perfect for 6-9 year olds is out on 28th August in the UK: https://amzn.eu/d/9kFiniD (message her on iszi.com if you want international posting).

One end-of-life issue many people face is deciding whether to become an organ donor. Australia's Organ and Tissue Authority is urging members of multicultural communities to consider the option, to help save lives. It's part of DonateLife Week, aimed at raising national awareness, and encourage more Australians to become organ and tissue donors. - В Австралии проходит неделя DonateLife Week. Представителей разных культурных общин призывают рассмотреть возможность стать донорами органов и тканей. Для этого нужно лишь зарегистрироваться в системе. Рассказываем истории Ричарда Локидена, которому дважды пересаживали печень, и Елены Рид, сыну которой понадобилась трансплантация печени.

One end-of-life issue many people face is deciding whether to become an organ donor. Australia's Organ and Tissue Authority is urging members of multicultural communities to consider the option, to help save lives. It's part of DonateLife Week, aimed at raising national awareness, and encourage more Australians to become organ and tissue donors. - آسٹریلیا جیسے ترقی یافتہ ممالک میں زندگی کے اختتام پر مرحوم کے ورثا کو اسکےاعضا کے عطیہ کرنے کا مرحلہ بھی درپیش ہوتا ہے۔۔ آسٹریلیا کی "آرگن اینڈ ٹشو اتھارٹی" مختلف ثقافتی پس منظر رکھنے والے افراد سے درخواست کر رہی ہے کہ وہ اس آپشن پر غور کریں، تاکہ قیمتی جانیں بچائی جا سکیں۔

One end-of-life issue many people face is deciding whether to become an organ donor. Australia's Organ and Tissue Authority is urging members of multicultural communities to consider the option, to help save lives. It's part of DonateLife Week, aimed at raising national awareness, and encourage more Australians to become organ and tissue donors.

Fixation on Histology: Remembering the Person Behind the Pieces of Tissue Written based on the webinar Remembering Why—a Review of Patient Case Studies  To Read the Full Blog Click Here

This episode of TTCL will feature an interview with Luis Santiago from NFH on La Mega. This monthly interview will inform the Spanish Community about Network For Hope and the incredible miracles that happen with Organ, Tissue, and Eye Donation. Resources: https://getoffthelist.org/ https://www.networkforhope.org/ https://www.networkforhope.org/about-us/ https://www.facebook.com/NetworkForHopeOPO https://aopo.org/ RegisterMe.org/NetworkforHope

Thanks for tuning into The Runners Zone Podcast.     Want to work with runners and build a thriving business around it? The Runner's Zone is an upbeat, global online community of clinicians, coaches, and trainers who love working with endurance athletes.  For over 10 years, we've helped passionate professionals fast-track their skills, grow their confidence, and build beautiful, word-of-mouth businesses that runners rave about. Join us if you're ready to level up—and have fun doing it. Use code “rzpod” for 10% off the annual membership. To learn more click HERE. Episode Timestamps 1:00 PTs should have a nationwide license 6:20 How much running is too much article 10:40 Principles for progressing a runner's training load 19:00 Life loads versus training loads 23:45 Tissue specific training considerations31:00 When training isn't working anymore Studies from this episode -  How much running is too much?  Bone stress injuries

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This episode was recorded at the 2025 Florida Ruminant Nutrition Symposium.  Dr. Baumgard begins with an overview of his presentation, “Importance of gut health to drive animal performance and health.” He notes the metabolic and inflammatory fingerprint of all stressors is essentially the same, indicating they likely all emanate from the gut. Overall, we're gaining a better understanding of how typical on-farm stressors negatively influence gut barrier function. He thinks the most likely mechanism of leaky gut is the immune cell known as a mast cell. When an animal or human is stressed, the enteric nervous system releases corticotropin-releasing factor, which binds to the mast cell, the mast cell degranulates, and the former contents of the mast cell (TNF-alpha, proteases, histamine, etc.) causes the gut to become leaky. (4:20)Once the GI tract barrier becomes compromised, antigens like lipopolysaccharide (LPS) can infiltrate, stimulating the immune system. Immune activation causes loss of appetite much like any other infection. The gut heals fairly quickly upon removal of the stressor(s), and the gut can also acclimate to stress such that the early stages of a stress event are more severe than later stages. Strategies to combat leaky gut remain scarce, and there is no silver bullet. There are a variety of dietary strategies to target the gut permeability issue itself. Another approach would be to bind pathogens or curb their proliferation at the membrane of the small intestine. (7:06)Dr. Neiehues asks if an antihistamine would work on gut mast cells the way it does in other body systems. Dr. Baumgard isn't sure that's ever been looked at, although there have been some studies in pigs using a product targeted to prevent mast cell degranulation. Dr. Nelson wonders if we should interfere in some of these processes because they're obviously there for a reason. Panelists discuss stress events related to parturition and transition, particularly for first-calf heifers. Dr. Baumgard notes that stacking stressors on top of one another compromises an animal's ability to tolerate stress. (9:28)We know stress can cause ulcers in humans and horses - what about ruminants? Dr. Baumgard thinks it is likely that it's happening, but we aren't looking for it. Few animals who die on-farm do receive a thorough postmortem exam. It could also be that these types of insults to the gut are not visible to the naked eye. (19:11)Dr. Nelson asks what makes some cows, despite all the challenges, able to be up and milking 150 pounds a day in no time after calving. What makes them unique? Dr. Baumgard lists some possibilities, including lower pathogenic inflammation than other cows, less tissue trauma damage to the uterus during calving, and lower sensitivity to immune activation. The panel disagrees with the notion that high-producing cows are stressed. (23:16)Dr. Niehues and Dr. Baumgard trade stories of experiments where cows maintained production even with high stress and inflammatory markers. The panel goes on to discuss subclinical infections and their impact on transition cows. Dr. Nelson notes there are retrospective datasets where cows who had metritis showed decreased feed intake even before calving. Dr. Baumgard feels that the decrease in intake has been incorrectly assumed to be the cause of the metritis. He says the decrease in intake is often around two weeks before calving and he doesn't think it's a coincidence that at the same time, the mammary gland is initiating lactogenesis. He hypothesizes the mammary gland is causing an immune response, resulting in a decrease in intake. Dr. Nelson wonders if measuring somatic cell counts of colostrum would show any differences in mammary gland inflammation during this prepartum period. (29:18)Panelists share their take-home thoughts. (42:02)Please subscribe and share with your industry friends to invite more people to join us at the Real Science Exchange virtual pub table.  If you want one of our Real Science Exchange t-shirts, screenshot your rating, review, or subscription, and email a picture to anh.marketing@balchem.com. Include your size and mailing address, and we'll mail you a shirt. 

This episode was originally released under Raw Health Rebel and I had to bring this one back.This episode with Steve Falconer (filmmaker, researcher and creator of Spacebusters) is still the most downloaded podcast I've ever released — and with good reason.We go deep into Schuessler's Tissue Salts — the 12 core mineral remedies that support your health at the most physical, energetic and emotional levels — and how they map across to the Zodiac signs in ways that might just blow your mind.Whether you're into astrology or not, what Steve shares here is both grounded and deeply illuminating — especially if you've ever wondered why certain symptoms keep showing up in your life, or your child's.We talk:Why your Sun sign is only one part of the puzzleWhat the next two signs after your birthday can tell you about your weaknessesHow salt imbalances can show up as emotional patterns or chronic issuesThe forgotten connection between astrology and cell saltsHow this knowledge empowers you to take health into your own handsWhy tissue salts are not supplements and how they work energeticallyThis episode is raw, unfiltered and full of strong language but also full of heart, deep insight and genuine tools for transformation.

Thank you for listening to The Peptide Podcast. If you enjoyed the show and want to support what we do, head over to our Partners Page. You'll find some amazing brands we trust—and by checking them out, you're helping us keep the podcast going.  Today we're going to talk about thymosin alpa 1, what it is, how it works, and why some doctors are using it to help those with Lyme disease What Is Thymosin Alpha 1? Let's start with the basics. Now we've talked about thymosin alpha 1 before in the context of immune health, but as a quick refresher, Thymosin alpha 1, or Tα1, is a peptide — a small chain of amino acids — that occurs naturally in the body.  It was first isolated from the thymus gland, which is an important immune organ responsible for developing and regulating T cells, especially during childhood. T cells are a type of white blood cell that play a central role in the immune system by identifying and destroying infected or abnormal cells and coordinating immune responses. Over time, our thymus shrinks and our immune response tends to slow down — which may partly explain why chronic infections or immune dysregulation become more common with age. Thymosin alpha 1 acts like an immune system coach — it doesn't directly kill pathogens, but it enhances the immune system's ability to detect and fight infections. In fact, it's made a big impact around the world.   Since its discovery in the 1970s, it's been used in over 35 countries to help treat conditions like hepatitis B and C, certain cancers, and even sepsis. During the COVID-19 pandemic, researchers explored its potential to calm immune overreactions and improve patient outcomes. It's also popular in veterinary medicine for helping dogs with chronic infections. Plus, some doctors are now investigating its role in boosting vaccine effectiveness and supporting people with autoimmune diseases or age-related immune decline — making thymosin alpha 1 a real immune multitasker. Thymosin Alpha 1 and Lyme Disease So why are doctors using thymosin alpha 1 in Lyme disease? Well, for many people, Lyme can become a long, drawn-out illness. And while antibiotics are usually the first-line treatment, some patients don't recover fully — instead, they develop lingering symptoms like fatigue, brain fog, joint pain, or neurological issues. This condition is known as Post-Treatment Lyme Disease Syndrome, or PTLDS — and we'll dive deeper into that in just a minute. In Lyme patients, Thymosin alpha 1 is being used off-label to: Rebalance the immune system Enhance the activity of T cells and natural killer cells Calm overactive inflammation Reduce the intensity and frequency of flare-ups or immune crashes Doctors report that patients using thymosin alpha 1 often feel more resilient — with improved energy, mental clarity, and fewer immune complications — especially in cases involving co-infections like Babesia, Bartonella, or Epstein-Barr virus. What Is PTLDS? Now let's dig into what happens after Lyme disease treatment for some patients. Post-Treatment Lyme Disease Syndrome, or PTLDS, affects roughly 5 to 20 percent of people who have been treated for Lyme disease. Even after completing a full course of antibiotics, they continue to experience significant symptoms that can last for months — or even years. Some of the most common symptoms of PTLDS include: Chronic fatigue that doesn't improve with rest Brain fog, poor memory, or difficulty concentrating (sometimes called 'Lyme brain') Joint and muscle pain Sleep disturbances Numbness, tingling, or burning sensations (peripheral neuropathy) Depression, anxiety, or mood swings Sensitivity to light, sound, or smells Dizziness or balance issues And often, fluctuating or cyclical symptoms — where you feel better for a while, then suddenly crash These symptoms can be disabling, and they're often not reflected in standard lab tests, which can make patients feel dismissed or misdiagnosed. Why Does PTLDS Happen? Researchers are still working to understand why PTLDS happens, but here are some of the leading theories: Immune system dysregulation – The infection may trigger a chronic inflammatory state that lingers long after the bacteria are gone. Persistent infection – Some believe the bacteria can go into a low-metabolic or dormant state, evading antibiotics and reactivating later. Tissue damage – Nerve and joint tissues may have been injured and take a long time to heal. Autoimmune activation – The body may start attacking its own tissues after the infection — similar to what happens in rheumatic fever. Undiagnosed co-infections – Other pathogens like Bartonella or Babesia may still be active and complicate recovery. This is where thymosin alpha 1 may offer a new path — not as a cure, but as a modulator that can help restore immune balance and reduce inflammatory damage. Thymosin Alpha 1 Risk Factors and Who Should Avoid It Thymosin alpha 1 is generally considered safe and well tolerated, especially because it mimics a peptide your body already makes. But like all therapies, it's not for everyone. Possible side effects include: Mild injection site reactions Fatigue, nausea, or headache (usually early in treatment) Not everyone is a good candidate for thymosin alpha 1, so it's important to know who should be cautious. For starters, if you're pregnant or breastfeeding, it's best to avoid it—there just isn't enough safety data available yet. People taking immunosuppressant medications, like those who've had organ transplants, should also steer clear because thymosin alpha 1 stimulates the immune system and could interfere with those drugs. And if you have an autoimmune condition, it's a bit of a gray area. While some people tolerate it well with low, carefully monitored doses, others might experience a flare, so it's definitely something to discuss with a knowledgeable healthcare provider. It's best to always consult with a healthcare provider experienced in peptide therapies and Lyme disease before starting treatment. The Bottom Line So to sum it all up, thymosin alpha 1 is a promising immune-supporting peptide that's gaining attention in the world of chronic illness—especially for conditions like Lyme disease and PTLDS. It's not a replacement for antibiotics and it doesn't directly kill infections, but it may help bring balance to an immune system that's either overreacting or underperforming. It's also being used to calm inflammation, support healing, and help people feel more resilient as they work through long-term symptoms. If you or a loved one are struggling with lingering symptoms from Lyme disease, chronic fatigue, or an immune system that just won't seem to bounce back, you're not alone. Talk to your family physician and ask if they can steer you toward a specialist familiar with peptide therapy and Lyme disease. Thank you for listening to The Peptide Podcast. If you enjoyed the show and want to support what we do, head over to our Partners Page. You'll find some amazing brands we trust—and by checking them out, you're helping us keep the podcast going.  Until next time, be well, be patient, and as always, have a happy, healthy week.

How fast can you gain or lose fat?  How fast can you gain or lose muscle?  In today's podcast we discuss the rate of change for fat and muscle along with my best recommendation for testing and tracking body composition!

The first phase of the Human Tissue Act 2024 is due to come into operation from today, meaning everybody will be considered an organ donor unless they opt-out or are included in a so-called excluded group. The act will introduce an opt-out system of consent for organ donation and will allow for altruistic living organ donation to strangers. Shane spoke to 29 year old Jessie Doyle, who has received two kidney transplants.

This is a continuation of a 4 part series on the topic of tissues. This episode discusses the nervous tissue.

Join us on this episode as we delve into a "silent epidemic" affecting millions: meniscus root tears, a leading cause of knee arthritis. Our guest, Dr. Chris Anderson, founding surgeon and Chief Medical Officer of Native Orthopedics, reveals the hidden prevalence of this debilitating injury, explaining how it impacts over 800,000 Americans annually and the critical need for a new approach to knee preservation. This episode uncovers why this problem has been historically overlooked and the limitations of traditional repair methods.Discover how Native Orthopedics is revolutionizing soft tissue repair with their FDA breakthrough-designated "Dragonfly" device. Dr. Anderson shares the ingenious, "finger trap" mechanism behind this knotless and adjustable solution, designed by a surgeon for surgeons. Learn how this innovation simplifies complex procedures, improves biomechanical repair, and is poised to introduce a new era of light-touch surgical solutions across sports medicine and beyond, promising better outcomes and faster recovery for patients. A fishing inspired tale that is sure to leave you informed and inspired.

This episode of TTCL will feature an interview with Luis Santiago on La Mega. This monthly interview will inform the Spanish Community about Network For Hope and the incredible miracles that happen with Organ, Tissue, and Eye Donation. Resources: https://getoffthelist.org/ https://www.networkforhope.org/ https://www.networkforhope.org/about-us/ https://www.facebook.com/NetworkForHopeOPO https://aopo.org/

Discover how tissue culture can rejuvenate legendary strains, restoring plant health and vigor, in this insightful interview for growers everywhere. In this episode, legendary cultivator Kyle Kushman sits down with Phil from Economic Laboratory to dive into the world of plant tissue culture and propagation. They explore how meristem tissue culture techniques can rescue and revitalize legacy medicinal strains (like the famed Strawberry Cough) that have lost vigor or been affected by diseases over time. You'll learn the differences between meristem vs. nodal propagation, the benefits and limitations of tissue culture, and why input material quality is crucial – reinforcing the mantra that “inputs determine outputs.” The conversation also tackles common misconceptions, emphasizing that tissue culture isn't a magic silver bullet. Kyle shares a personal story of completely restarting his grow and how tissue culture helped bring back his cherished strain to its former glory. Phil explains the realistic expectations growers should have when using these advanced techniques to clean up and multiply their prized genetics. Additionally, discover the services Economic Laboratory offers – from accepting plant samples from growers nationwide to returning pest- and pathogen-free plantlets – and get a sneak peek at innovations on the horizon (hint: new propagation methods that could revolutionize how we start our plants). This description packs everything you need to know about reviving legendary strains and preserving your plant's health through modern tissue culture technology, all while staying safe and compliant in today's cultivation industry. Highlight Moments08:0413:2020:3229:35If this video planted some new ideas in your mind, give it a green thumbs-up!

In part two of this two-part series, Dr. Jeff Ratliff and Dr. Per Borghammer explore the subcategories of Lewy body disease, focusing on the body-first subtype Show reference: https://www.nature.com/articles/s41593-025-01910-9 

In part one of this two-part series, Dr. Jeff Ratliff and Dr. Per Borghammer examine the dichotomy that existed before his team began this project. Show reference: https://www.nature.com/articles/s41593-025-01910-9 

In this episode: President Trump's tour of the Middle East sees key deals signed and sanctions rolled back - what does it mean for the region? Plus, Prime Minister Albanese's diplomatic balancing act with Indonesia's leader, what the results of the Philippines midterms mean for two political dynasties, the latest on Ukraine peace negotiations, and how a used tissue became a tool of wartime propaganda.

Dr. Jeff Ratliff talks with Dr. Per Borghammer about the classification of Lewy body disease into brain-first and body-first subtypes, with a focus on the newly identified parasympathetic and sympathetic subtypes within the body-first category.  Read the related article in Nature.  Disclosures can be found at Neurology.org. 

Send us a textThis is easliy the grossest question yet, but *checks notes* Glenn Braley handles it with all the professionalism you'd expect from one of the south coast comedy scene's top hosts!The wheel of misfortune has delivered a doozy, and the boys aren't one to shy away from the nitty gritty of it. (Simon would like to apologise to everybody now)So join the discussion, have your say, and let us know... which would you chose?Glenn BraleyWhen Glenn started running nights in 2019 there was no grass roots comedy available in Bournemouth. Today he's involved with developing local talent, comedians and promoters.Website -  https://www.comedynoir.co.ukFacebook - https://www.facebook.com/GlennBraleyComedyInstagram - https://www.instagram.com/glenn_braley_comedyTokTok - https://tiktok.com/@glennbraleycomedyYouTube -  https://youtube.com/@glennbraleycomedy9834Who Takes the Socks Off is now a part of the Channel 84 Podcast Network Family!Click here for more informationSupport the showHelp the Socks! Enjoying the episodes? You can help keep the mics on & the episodes flowing (if you can afford to). Head over to our Ko-Fi page & check out the options.Ko-Fi: https://ko-fi.com/sockspodSocialsTwitter: https://twitter.com/whotakesocksoffBlueSky: https://bsky.app/profile/socks.channel84.co.ukFacebook: https://www.facebook.com/whotakesthesocksoffInstagram: https://www.instagram.com/whotakesthesocksoffReview our thread count (5 stars only please, we're sensitive socks)Goodpods: https://goodpods.com/podcasts/who-takes-the-socks-off-204195Podchaser / iTunes: https://ratethispodcast.com/socksEverything ElseLinktree: https://linktr.ee/whotakesthesocksoffWe're part of the Studio:Channel84 Support Network.Studio: Channel 84 Network: ht...

Send us a textOn this episode of the UnsCripted Medicine podcast, host Molly Carroll is joined by Nick Weissman to talk about his experience with dissection here at the University of Cincinnati College of Medicine. As an incoming general surgery intern, Nick reflects on the opportunity to get hands-on experience with anatomy early on here at UCCOM, an experience that is becoming more unique as virtual dissecting becomes more popular. As M4s, both Nick and Molly stepped into the role of teachers with the Anatomical Sciences Teaching Elective and chat about this transition, as well as what makes Cincinnati's program so special. We hope you enjoy!References:Does exposure to anatomy education in medical school affect surgical residency applications? An analysis of Canadian residency match data — https://pmc.ncbi.nlm.nih.gov/articles/PMC7828959/The Effectiveness of a Virtual Anatomy Curriculum Versus Traditional Cadaveric Dissection in UNC SOM's First-Year Class — https://pmc.ncbi.nlm.nih.gov/articles/PMC9517981/A body donated to science - but used to test bombs — https://www.bbc.com/news/world-us-canada-49198405.amp

This week Brooke McPoyle, a fascial educator and breathwork teacher, discusses the crucial role of fascia in overall health and well-being. The conversation explores fascia's impact on chronic pain, mood, brain fog, and chronic diseases, highlighting its often-overlooked importance. McPoyle explains fascia's structure and function, emphasizing the significance of hydration, movement, and breathwork for maintaining healthy fascia. The discussion delves into the effects of aging, modern footwear, and environmental factors on fascia, offering practical advice for improving fascial health through self-massage techniques (specifically, the "Fascial Flow" method), mindful breathing exercises, and conscious hydration with high-quality water. #fascia #relief #massage ==== Thank You To Our Sponsors! Timeline Go to timeline.com/DRG for 10% off your order! Puori Click here https://puori.com/drg and use code DRG for 20% off the already discounted subscription prices. Cornbread Hemp Use code DRG to save 30% off your order at cornbreadhemp.com/drg ==== Website: musicalbreathwork.com Instagram: @musicalbreathwork YouTube: Musical Breathwork Vicus Water: Discount code 15% Off: VICUSBROOKE Timestamps: 00:00:00 - Fascia, Breathwork, Body Awareness 03:25 - Fascia, Mood, Chronic Pain 09:12 - Fascia, Structure, Aging 16:00 - Foot Health & Tech Dangers 22:17 - Hyaluronic Acid & Water's Role 28:29 - Body Awareness & Inner Energy 34:53 - Breath Control for Athletes 41:08 - Breathwork, Fascia, Trauma 56:28 - Fascia Release Techniques 1:04:59 - Breathwork Course Offerings 1:13:15 - Body Awareness Workshop Be sure to like and subscribe to #HealThySelf Hosted by Doctor Christian Gonzalez N.D. Follow Doctor G on Instagram @doctor.gonzalez https://www.instagram.com/doctor.gonzalez/ Sign up for our newsletter! https://drchristiangonzalez.com/newsletter/

HR1 Dr. Scott Faulkner: Public/Private Tissue Banking. Value of Umbilical Cords & Stem Cells 4-30-25 by John Rush

This week on The Beat, CTSNet Editor-in-Chief Joel Dunning speaks with Dr. Cristiano Spadaccio, an attending cardiac surgeon and associate professor of surgery at the University of Cincinnati College of Medicine, Ohio, USA, about totally tissue-engineered valves for tricuspid replacement. Chapters 00:00 Intro 01:48 Tissue-Engineered Valves 05:48 Compensatory Sweating After BETS 10:05 5Y Outcomes TAVR vs SAVR 13:34 ChatGPT CT Surgery Insights 17:24 Retraction Speed Pain RC Trial 21:21 Ross Procedure, All-Native Valve 25:43 Endoscopic Mechanical MVR 28:10 Double Patch Double Valve Exploration 31:42 Dr. Spadaccio, Generative Valves 50:38 Upcoming Events 51:52 Closing They focus on the CorMatrix Cor TRICUSPID ECM Valve, including the technique for valve implantation, the functionality of the valve and its underlying concept, and the valve's history, particularly its applications in pediatric patients. The episode features videos and photos showcasing the valve, the implantation procedure, and more. Additionally, they discuss the critical role of identifying the papillary muscle in this surgery and whether an anoplasty ring is necessary. They also explore the current status of the valve and its future prospects.   Joel also highlights recent JANS articles on the long-term outcomes and predictors of compensatory sweating after bilateral endoscopic thoracic sympathectomy, five-year outcomes after transcatheter or surgical aortic valve replacement in low-risk patients with aortic stenosis, navigating the future of pediatric cardiovascular surgery using Chat Generative Pre-trained Transformer (ChatGPT), and a randomized controlled trial on retraction speed and chronic poststernotomy pain.   In addition, Joel explores the Ross procedure using the right atrial appendage valve instead of a homograft, totally endoscopic mechanical mitral valve repair, and an exploration on reoperation technique for double patch double valve with Drs. Leonard Lee and Vince Gaudiani. Before closing, he highlights upcoming events in CT surgery.   JANS Items Mentioned  1.) Long-Term Outcomes and Predictors of Compensatory Sweating After Bilateral Endoscopic Thoracic Sympathectomy  2.) 5-Year Outcomes After Transcatheter or Surgical Aortic Valve Replacement in Low-Risk Patients With Aortic Stenosis  3.) Navigating the Future of Pediatric Cardiovascular Surgery: Insights and Innovation Powered by Chat Generative Pre-Trained Transformer (ChatGPT)  4.) Retraction Speed and Chronic Poststernotomy Pain: A Randomized Controlled Trial  CTSNET Content Mentioned  1.) Ross Procedure Using the Right Atrial Appendage Valve Instead of a Homograft: An All-Native Valve Approach  2.) Totally Endoscopic Mechanical Mitral Valve Repair  3.) Reoperation Technique for Double Patch Double Valve: An Exploration With Leonard Lee and Vince Gaudiani  Other Items Mentioned  1.) Endoscopic Cardiac Surgery Series: The Swiss Army Knife Approach  2.) Expert Discussion Videos   3.) Career Center   4.) CTSNet Events Calendar  Disclaimer The information and views presented on CTSNet.org represent the views of the authors and contributors of the material and not of CTSNet. Please review our full disclaimer page here.

A problem so big, it's nothing to sneeze at.  Until it is.  Grab some tissues cause we're gonna chat about our issues. This includes dad jokes so bad they'll bring a tear to your eyes.

Welcome to the land podcast, a platform for people looking to educate themselves in the world of land ownership, land investing, staying up to date with current land trends in the Midwest, and hearing from industry experts and professionals. On today's episode, Dive deep into the world of land investment and whitetail management with seasoned expert, Tyler Tissue! Discover if the strategies of the '90s still work today, how to score big on land deals, and what the future holds for whitetail hunting properties. Is land buying of the '90s repeatable now? Tiny tweaks for massive bucks Partnering up in land: Boon or bust? Facing off with the future of big deer hunting Debunking land investment myths Impact of technology on hunting The future of whitetail hunting & land value Impact of EHD on deer management ⁠https://www.whitetailmasteracademy.com⁠ ⁠Use code '⁠HOFER' to save 10% off at ⁠www.theprairiefarm.com⁠ ⁠Massive potential tax savings: ⁠⁠ASMLABS.Net⁠ -Moultrie: ⁠https://bit.ly/moultrie_⁠ -Hawke Optics: ⁠https://bit.ly/hawkeoptics_⁠ -OnX: ⁠https://bit.ly/onX_Hunt⁠ -Painted Arrow: ⁠https://bit.ly/41ZtK5i⁠ 

The Steve Harvey Morning Show for Wednesday, April 16th, 2025: Steve gives Junior a pep talk as he prepares to speak before the Texas State Senate on new Sickle Cell legislation. Michelle Obama addresses speculation that she and the former President are getting a divorce. A$AP Rocky says he knew Rihanna was in the courtroom for his acquittal...find out how. The crew discuss classic TV shows and singing groups they would bring back. There's another crazy Strawberry Letter, Ask The CLO, Would You Rather, & more!Support the show: https://www.steveharveyfm.com/See omnystudio.com/listener for privacy information.

Detroit rapper, Kash Doll, recently made waves on social media after she posted a video, blowing her nose while sitting at a recent Pistons vs. Bucks game. The video was trending because she was blowing her nose with a $20 bill.Steve Harvey Morning Show Online: http://www.steveharveyfm.com/See omnystudio.com/listener for privacy information.

Fixation on Histology Blog: Where Does Tissue Contamination Happen Most? Based on the Webinar By: Valerie Cortright, BA, HT(ASCP), HTL(ASCP), QIHC Click to read this post.

Is this considered rude or just taking care of business?! Hosted on Acast. See acast.com/privacy for more information.

Dr. Vamsi Velcheti and Dr. Charu Aggarwal discuss the evolution of ctDNA as a critical tool in precision oncology and its implications for lung cancer management, including its potential role in the early-stage setting. TRANSCRIPT Dr. Vamsi Velcheti: Hello. I am Dr. Vamsi Velcheti, your guest host for the ASCO Daily News Podcast today. I am a professor of medicine and director of thoracic medical oncology at the Perlmutter Cancer Center at NYU Langone Health.  The management of small cell lung cancer has rapidly evolved over the past few decades, and today, molecular testing and biomarker testing for lung cancer are absolutely critical in terms of designing treatment options for our patients with metastatic non-small cell lung cancer. Today, I'm delighted to be joined by Dr. Charu Aggarwal for a discussion on ctDNA (circulating tumor DNA) and the role of ctDNA in lung cancer management. Dr. Aggarwal is the Leslye Heisler Professor of Lung Cancer Excellence and section chief of thoracic and head and neck oncology at University of Pennsylvania Abramson Cancer Center.  You'll find our full disclosures in the transcript of that episode.  Dr. Agrawal, it's great to have you on the podcast today. Thank you for being here. Dr. Charu Aggarwal: Thank you for having me. Dr. Vamsi Velcheti: Let's start off with setting the stage for ctDNA technology. These technologies have rapidly evolved from experimental conceptual stage to essential clinical tools for day-to-day clinical practice. Could you briefly discuss how recent advancements in ctDNA technologies are shaping our approach to precision medicine, especially in lung cancer? Dr. Charu Aggarwal: Absolutely. And you know, I think we need to just level set a little bit. What exactly is circulating tumor DNA? This is a way to assess exactly that. Every tumor sheds little pieces of tumor-derived DNA into the bloodstream, and this occurs in a variety of solid tumors. But now we have the technology to be able to derive this DNA that's actually being shed from the tumor into the bloodstream, these minute fragments of DNA, take them out, amplify them and sequence them with a variety of different mechanisms. They can be DNA sequencing alone, they can be DNA and RNA sequencing, they can be whole transcriptome sequencing. The technology, as you rightly pointed out, Dr. Velcheti, has significantly improved from just being able to look at circulating tumor DNA to now being able to amplify it, sequence it, and use it to offer personalized therapy. I think lung cancer is definitely the poster child for such an approach as we have a lot of data that has shown clinical utility and validity of being able to use circulating tumor DNA next-generation gene sequencing to guide therapy. Dr. Vamsi Velcheti: There have been so many technological leaps. It's really impressive how far we've come to advance these sequencing platforms. Recent advances with AI and machine learning are also playing important roles in interpreting ctDNA data. How are these computational advances really enhancing clinical decision-making in day-to-day clinical practice? Dr. Charu Aggarwal: I think while we have firmly established the role of ctDNA in the management of patients with metastatic lung cancer, some of the approaches that you talked about are still experimental. So let me backtrack a little bit and set the stage for how we use ctDNA in clinical practice right now. I think most patients, when they come in with a new diagnosis of stage IV lung cancer, we want to test for biomarkers. And this should actually be the established standard. Now included in the NCCN guidelines and actually also international guidelines, is to consider using blood-based testing or plasma-based testing to look for biomarkers, not just tissue-based testing which had been our historical standard, but to use these plasma guided approaches to identify the seven to nine biomarkers that may be truly implicated in either first- or second-line therapy that are called as your immediately actionable mutations.  What you're talking about is AI computational methods. I think there's a lot of excitement about how we can use genomic signatures that are derived from either tissue or ctDNA-based biomarker testing, combine it with radiomic features, combine it with histologic features, look at H & E patterns, use AI algorithmic learning to be able to actually predict recurrence scores, or can we actually come up with predictive signatures that may be extremely helpful?  So, I think some of the techniques and technologies that you're talking about are incoming. They are provocative. I think they're very exciting, but very early. Dr. Vamsi Velcheti: I think it's really amazing how many advances we have with these platforms. You know, the challenge really is the significant gap in terms of uptake of molecular testing. Even today, in 2025, there are significant gaps in terms of all metastatic lung cancer patients being tested for all biomarkers.  So, why do you think there's such a challenge in testing patients with lung cancer? In most academic practices, we try to achieve 100% testing for all our patients, but we know from recent studies that that's not the case across the country. What do you think the gaps are? Dr. Charu Aggarwal: Biomarker testing is so essential, like you pointed out, for us to be able to guide the right therapy for our patients. And we see this in our practice every day as you and I see patients with lung cancer, that a large proportion of our patients either don't get tested or they start therapy before their test results come back. So, I think this is a real problem.  However, to add some optimism to this problem, I do think that we are making a move in the right direction. So, four or five years ago, there was a lot of data being presented at national meetings, including ones from the American Society of Clinical Oncology, where we saw that, nationally, the rates of biomarker testing were probably in the rate of 40 to 50%. However, now with the availability of both tissue and plasma, I do think that the rates of biomarker testing are increasing. And if you were to survey a sample or even perform retrospective data research, I believe that the number is closer to 70% of all patients with metastatic non-small cell lung cancer.  And you know, you asked why is it not 100%? I think there are many reasons. I think the number one reason is tissue availability. Many times, the biopsies are small, or the tumor is very necrotic. So, either the tissue quantity itself is small, or the tissue quantity is insufficient to perform gene sequencing. And that's exactly where plasma comes in. When you don't have tissue availability, we have shown, as have others, that you can use plasma effectively to increase the proportion of patients who are not only tested but also receive the right therapy. I think there are also other barriers, including inertia. You know, I think this is both patient and physician inertia, where patients want to get started quickly, they don't want to wait. Physicians are very busy and sometimes want to be able to deliver treatment as soon as possible. We have seen there are some institutional barriers. Not every institution has in-house gene sequencing testing. So how do you really operationalize, send out these tests in a fast, efficient manner so that you get results back? Is it a pathologist who sends out the test? Is it the medical oncologist? Is it the pulmonologist or the interventionalist? I think there is this need to develop reflex testing mechanisms which some institutions do really well and some don't. And then finally, there are financial implications as well. How do we do this in a most cost-efficient fashion?  So there are many barriers, but I'm happy to say that we are making a move in the right direction as we are understanding that it's important to do it, it's easy to do it maybe with a value add of plasma, and finally, as you said, you know, as these technologies become more available, they're actually getting more cost-effective. Dr. Vamsi Velcheti: Dr. Aggarwal, you've been at the cutting edge of these advanced platforms and testing. So, what do you do in UPenn? How do you handle all these barriers and what is your workflow for patients in University of Pennsylvania? Dr. Charu Aggarwal: One of the things that I mentioned to you was there may be institutional barriers when it comes to gene sequencing. So, we actually, several years ago now, instituted a very robust reflex testing paradigm where almost all of our patients, regardless of stage, with a non-squamous non-small cell lung cancer diagnosis, would automatically be reflexively sent to our molecular pathology lab where they would get gene sequencing both for the DNA as well as with an RNA fusion-based platform. And the reason we did this was because we wanted to expedite and reduce the turnaround time. We also wanted to ensure that we were not just doing DNA testing, which I think is really important for our listeners here. There are many fusions as well as certain skipping mutations like MET exon 14 that may be missed on DNA testing alone. So, it's really incredibly important to run both DNA and RNA samples.  So, we do this routinely, and based on our research and others, what we also do routinely is that we send concurrent tissue and liquid biopsies or plasma MGS testing upon initial diagnosis. For example, if a patient comes in with a diagnosis of stage IV non-small cell lung cancer, their tissue might already be at my molecular pathology lab based on the reflex mechanism that I just described to you. But upon their initial meeting with me, we will send off plasma. And I will tell you this, that Penn is not just one institution, right? We have a large network of sites. And as part of my research, one of the things that we wanted to do was implement wide scale means to improve biomarker testing. And we have done this with the use of technology like you mentioned, Dr. Velcheti: How can we actually use AI? How can we leverage our electronic medical record to identify these patients? So, we have a nudge-based mechanism which actually facilitates the pending of orders for biomarker testing for patients with new diagnosis of metastatic non-small cell lung cancer. And we are looking at our rates of biomarker testing but also rates of completion of biomarker testing before first-line therapy started. So many of our participating sites are clusters for our randomized control trial to increase molecular testing. And I'm really excited about the fact that we're able to implement it not just at our main satellite, downtown Penn Hospital, but also across our community. Dr. Vamsi Velcheti: I think that's great. Thank you so much for those insights, Dr. Aggarwal. I think it's so important because having the best technology is just not enough. I think implementation science is actually a real thing. And I think we need to all learn from each other, advance these things.  So, I want to ask you about the new emerging paradigm in terms of using ctDNA. Of course, in the metastatic setting, we've been using ctDNA for molecular profiling for a while now. But the recent data around monitoring early-stage disease, especially post-operative monitoring, is an exciting area. There are a lot of opportunities there. Could you please talk us through the emerging data in lung cancer and how do we incorporate ctDNA-based monitoring MRD or should we even do that right now? Is the data ripe enough for us to kind of deploy this in a clinical setting? Dr. Charu Aggarwal: I think using ctDNA in the early-stage setting is our next frontier in lung cancer. I think naturally we have been able to successfully deploy this in the stage 4 setting. It made a meaningful difference in the lives of our patients, and we are a little bit behind the A ball in terms of how MRD is used in lung cancer. Because, you know, colorectal cancer has already done large-randomized trials based on ctDNA and MRD. It's routinely used in hematological malignancy. So, it makes sense that we should start to use it.  However, when I say this, I say this with excitement, but also a little bit of gentle caution saying that we actually don't quite have the prospective randomized data just yet on how to deploy. Yes, intuitively we would say that if you detect ctDNA and MRD, that patient is at higher risk. So, we identify that, but we actually don't know what to do with the second part of that information once you identify a patient with high risk. Are there other techniques that we can then come in with or other drugs that we can come in with to modify that risk? And that's the thing that I think we don't have right now. The other thing that we don't have right now is the timing of the assay, when to use it. Is it to be tested in the pre-op setting? Is the post-op test the best timing, or is it monitoring and dynamics of ctDNA that are most important? And the third thing I will say in terms of precautionary cause is that we don't know which test just yet. There are actually a few commercially available tests out in the market right now. We know about them and I'm sure our community colleagues know about them. Some of them even have Medicare approval. However, many of these tests are currently tissue informed. We don't have tissue uninformed tests. And what does that mean? Tissue uninformed means that you actually take a piece of tumor tissue, you sequence that tumor and based on the gene profile of that tumor, you actually design a panel that can then be used to track the mutations in the blood-based pack. This requires, as the name implies, a tumor. So can this be used in the pre-op setting is a large question. Because coming back to the idea of tissue availability, you and I both know that when we get FNAS and we use it for PDL-1 testing and we use it for gene sequencing, there often isn't enough tissue left for us to then either do whole genome sequencing or even whole transcriptome sequencing, which may be required to build some of these assays.  I think the future lies in this idea of tumor uninformed assays because if we could go to a blood only or a plasma only approach using novel signatures like proteomics or methylation, I think that's where the future is. But we're still a little bit early in the discovery stages of those, as well as to come are the validation stages so that we can be confident that these blood-only assays may actually give us an answer.  So, with those three cautionary notes, I would say that optimism is still very high. I think ctDNA MRD is the right place to think about. We need to do this for our patients to better identify high-risk patients and to think about means to escalate treatment for them. Dr. Vamsi Velcheti: Yeah, I completely agree, and I think with all the changes and evolution of treatments in the management of early-stage lung cancer now with neoadjuvant and adjuvant, there's really a need for an escalation and de-escalation of therapies post-operatively. And I think it's a huge opportunity. I think we all could learn from our colorectal colleagues. I think they've done a really good job at actually doing prospective trials in this setting. I think we're kind of a little behind here.  Dr. Charu Aggarwal: I think in the metastatic setting there are ongoing trials to look at this exact question. How do you choose an appropriate first-line therapy, a monitor ctDNA at the six-week trial? It's being evaluated in a trial called the “Shedders” trial, where if patients are still ctDNA positive at six weeks, then you can escalate treatment because they haven't “cleared” their ctDNA. There has been a lot of research that has shown that lack of ctDNA clearance in the metastatic setting may be a poor prognostic factor. We and others have shown that if you do clear your ctDNA or if you have a reduction in ctDNA load overall, that that is directly related to both an improved progression-free survival and overall survival. This has been shown with both tissue informed and uninformed assays. So I think it's very clear that yes, you can track it. I think the question is: Can you apply that data to the early-stage setting? And that's an open research question. A lot of groups are looking at that and I think it's completely reasonable, especially to determine duration of therapy, to determine optimal timing, optimal timing of scans even. And I think these are just such interesting questions that will be answered in the future. Dr. Vamsi Velcheti: And also like a kind of early detection of resistance patterns that might inform early initiation of combination strategies. And I think it's a lot of opportunities I think yet to be explored. A lot of exciting things to come and I'm sure we'll kind of see more and more data in the next few years.  Dr. Aggarwal, thank you so much for sharing your fantastic insights today on the ASCO Daily News Podcast. It's been a pleasure to have you on the podcast today. Hope to see you at ASCO. Dr. Charu Aggarwal: Thank you so much. This was great and I remain so excited by all of the possibilities to improve outcomes for our patients. Dr. Vamsi Velcheti: Thank you to all the listeners for your time today. If you value the insights that you hear from the ASCO Daily News Podcast, please take a moment to rate, review and subscribe wherever you get your podcast. Thank you so much. Disclaimer: The purpose of this podcast is to educate and to inform. This is not a substitute for professional medical care and is not intended for use in the diagnosis or treatment of individual conditions. Guests on this podcast express their own opinions, experience and conclusions. Guest statements on the podcast do not express the opinions of ASCO. The mention of any product, service, organization, activity or therapy should not be construed as an ASCO endorsement. Follow today's speakers:  Dr. Vamsidhar Velcheti  @VamsiVelcheti  @vamsivelcheti.bsky.social Dr. Charu Aggarwal @CharuAggarwalMD   Follow ASCO on social media:  @ASCO on X (formerly Twitter)  ASCO on Bluesky ASCO on Facebook  ASCO on LinkedIn    Disclosures: Dr. Vamsidhar Velcheti:  Honoraria: Glavanize Therapeutics Consulting or Advisory Role: Bristol-Myers Squibb, Merck, AstraZeneca/MedImmune, GSK, Amgen, Taiho Oncology, Novocure, Takeda, Janssen Oncology, Picture Health, Regeneron Research Funding (Inst.): Genentech, Trovagene, Eisai, OncoPlex Diagnostics, Alkermes, NantOmics, Genoptix, Altor BioScience, Merck, Bristol-Myers Squibb, Atreca, Heat Biologics, Leap Therapeutics, RSIP Vision, GlaxoSmithKline  Dr. Charu Aggarwal: Consulting or Advisory Role: AstraZeneca, Daiichi Sankyo/AstraZeneca, Regeneron/Sanofi, Pfizer, Boehringer Ingelheim, Takeda, Arcus Biosciences, Gilead Sciences, Novocure, Abbvie Speakers' Bureau: AstraZeneca (an immediate family member) Research Funding (Inst): Merck Sharp & Dohme, AstraZeneca/MedImmune, Daiichi Sankyo/AstraZeneca, Lilly@Loxo, Candel Therapeutics  

Fascia has been a hot topic in both research and hands-on therapy for some time now. While the idea that massage therapists affect more than just muscle isn't new, defining exactly what "the other stuff" is has proven trickier than expected. Today, multiple definitions of fascia are debated worldwide. To bring clarity and foster better communication, a new, unified definition has been proposed in the Journal of Anatomy (January 2025). Join hosts Rachelle Clauson and Nicole Trombley, co-directors of AnatomySCAPES, as they dive into this fascinating, global discussion, sharing insights from their recent participation at the Winter School Research Conference in Padua, Italy, on this episode of The ABMP Podcast. Resources and Author Links: www.anatomyscapes.com/MATRIX for more information about “Journey Into the MATRIX: the Fascial System” dissection lab workshop! Curious about this new proposed definition of fascia? Check it out here in the Journal of Anatomy:  https://pubmed.ncbi.nlm.nih.gov/39814456/ Join AnatomySCAPES for their upcoming fascia-focused webinar Scar Tissue: A View Beneath the Surface. This webinar will take place on May 1 and you can register for this FREE on their website: website: www.anatomyscapes.com FB: facebook.com/AnatomySCAPES IG: instagram.com/anatomyscapes YouTube: youtube.com/@anatomyscapes   Hosts:   AnatomySCAPES Co-Directors, Rachelle Clauson and Nicole Trombley, are NCBTMB-approved continuing education providers and teach anatomy explorations for hands-on professionals online and in person. They co-author the “Anatomy for Touch” column in Massage & Bodywork magazine and enjoy helping therapists better understand how anatomy relates to what they are feeling through their sense of touch.   Nicole Trombley: As a massage educator, Nicole draws on her passion for human biology to help therapists better understand the tissues under their hands. She owns and operates Equilibrio Massage in San Diego, CA, where she has specialized in massage for pregnancy and postpartum for the past 20 years.   Rachelle Clauson: Rachelle loves teaching therapists about the structural organization and beauty of the human fascial system. She served as the Director of Creative and Administrative Affairs for the Fascial Net Plastination Project, and owns Flourish Bodywork, her private practice where she has offered hands-on bodywork in San Diego, CA, for the past 21 years.   Sponsors:   Anatomy Trains: www.anatomytrains.com     American Massage Conference: https://www.massagetherapymedia.com/conferences   Anatomy Trains is a global leader in online anatomy education and also provides in-classroom certification programs for structural integration in the US, Canada, Australia, Europe, Japan, and China, as well as fresh-tissue cadaver dissection labs and weekend courses. The work of Anatomy Trains originated with founder Tom Myers, who mapped the human body into 13 myofascial meridians in his original book, currently in its fourth edition and translated into 12 languages. The principles of Anatomy Trains are used by osteopaths, physical therapists, bodyworkers, massage therapists, personal trainers, yoga, Pilates, Gyrotonics, and other body-minded manual therapists and movement professionals. Anatomy Trains inspires these practitioners to work with holistic anatomy in treating system-wide patterns to provide improved client outcomes in terms of structure and function.                      Website: anatomytrains.com                        Email: info@anatomytrains.com             Facebook: facebook.com/AnatomyTrains                       Instagram: www.instagram.com/anatomytrainsofficial   YouTube: https://www.youtube.com/channel/UC2g6TOEFrX4b-CigknssKHA     American Massage Conference   Get ready to immerse yourself in the excitement as the American Massage Conference (AMC) arrives to Disney Springs near Orlando, Florida (May 16th-18th, 2025)! With a legacy of 17 successful years in Ontario, Canada, this premier event, proudly hosted by ONE Concept Conferences and expertly produced by Massage Therapy Media (MTM), boasts a lineup of presenters from across the nation and around the globe.   The American Massage Conference began in Atlanta in 2011 and has been hosted through the years in San Diego, Chicago, and Virginia Beach. The conference provides educational opportunities with engaging one-, two-, three- and four-hour class formats, networking opportunities, masterminds, MTM Talks, demonstrations, and an extensive exhibitor tradeshow.     Mark your calendars for an unforgettable experience filled with education, networking, and the celebration of massage therapy excellence! ABMP members receive a special discount to attend this in-person conference—log in to your ABMP account to access the discount code and register today.   Website: https://www.massagetherapymedia.com/conferences

Hey Friend, Have you ever walked out of the doctor's office with this phrase stuck in your head?

Watch the video here: https://christianyordanov.com/tissue-salts-other-fun-stuff-brandon-thomas/ -------------Brandon Thomas, host of Expanding Reality, returns for another mind-expanding conversation! In this episode, we dive into the fascinating world of tissue salts—how they align with astrology, impact health, and keep us in balance with the natural world. Brandon shares insights on energy work, planetary transits, and the power of aligning with cosmic rhythms.Connect with Brandon:Website: https://www.expandingrealitypodcast.com/Expanding Reality Podcast: https://www.expandingrealitypodcast.com/copy-of-videoYouTube: https://www.youtube.com/channel/UCBrATGSZs2m-1-30_9VHPHwApple podcasts: https://podcasts.apple.com/us/podcast/expanding-reality/id1469846551 -------------Are you following health trends that actually harm your body? In my eye-opening masterclass "The 7 Popular But Deadly Health Fads," I reveal how common health practices promoted by influencers and gurus might be ravaging your gut, accelerating disease, and shaving years off your life.Discover which popular diets, supplements, and health rituals are secretly sabotaging your health and learn what to do instead. I explain why these seemingly healthy habits are damaging your body and provide actionable alternatives for true longevity.Register for free access to this essential health information at https://www.livelongerformula.com

TWiP explains a study which finds that tissue spaces are reservoirs of antigenic diversity for Trypanosoma brucei, then remembers our departed colleague Dickson Despommier. Hosts: Vincent Racaniello, Daniel Griffin, and Christina Naula Click arrow to play Download TWiP #254 (88 MB .mp3, 61 minutes) Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Links for this episode Join the MicrobeTV Discord server Tissue spaces are reservoirs of antigenic diversity for T. brucei (Nature) Understanding trypanosome antigenic variation (Emerg Top Life Sci) Tissue resident T. brucei (PLoS Path) Hero – Dickson Despommier Despommier Photo Art Parasitology Course (YouTube) Become a patron of TWiP  Send your questions and comments to twip@microbe.tv Music by Ronald Jenkees TWiP explains a study which finds that tissue spaces are reservoirs of antigenic diversity for Trypanosoma brucei, then remembers our departed colleague Dickson Despommier. Hosts: Vincent Racaniello, Daniel Griffin, and Christina Naula Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Links for this episode Join the MicrobeTV Discord server Tissue spaces are reservoirs of antigenic diversity for T. brucei (Nature) Understanding trypanosome antigenic variation (Emerg Top Life Sci) Tissue resident T. brucei (PLoS Path) Hero – Dickson Despommier Despommier Photo Art Parasitology Course (YouTube) Become a patron of TWiP  Send your questions and comments to twip@microbe.tv Music by Ronald Jenkees

In this episode of the Experience Miracles podcast, Dr. Tony Ebel discusses tongue ties from a perspective rarely addressed by other healthcare providers. While acknowledging that tongue and oral ties are real issues that can significantly impact breastfeeding, airway function, and development, Dr. Ebel explains why simply revising these ties often provides only temporary relief. He delves into the neurological root causes of tongue ties, describing them as compensatory mechanisms resulting from nervous system dysfunction. Dr. Ebel shares insights from his clinical experience about why addressing the underlying neurological issues through proper chiropractic care is essential for complete and lasting resolution of tongue tie symptoms and related challenges.[00:01:00] Introduction to Tongue TiesDefinition and terminology (oral ties, TOTs)Relevance for all ages, not just infantsConnection to broader health issues (sensory, airway, nervous system)[00:07:00] The Mechanical vs. Neurological UnderstandingWhy tongue ties are not just a mechanical issueComparison to ear tube surgeries and recurring problemsWhy improvements after revisions may be temporary[00:11:00] Four Myths About Tongue TiesMyth #1: It's just a mechanical problemMyth #2: Quick fixes work permanentlyMyth #3: If a baby has trouble latching, it's just a mouth issueMyth #4: It's just a nutritional deficiency/MTHFR issue[00:24:00] Understanding Subluxation and Its OriginsDefinition and origins of subluxationHow it can develop in-utero and during birthBirth interventions that commonly cause subluxationThe nerve connection to tongue function[00:29:00] The Solution ApproachNeurotonal adjustments explainedVagus nerve activation and nervous system regulationWhy a comprehensive approach is necessary[00:33:00] Whole-Body Connection and Working with PX DoctorsWhy children with tongue ties often have multiple issuesFinding a properly trained pediatric chiropractorEncouragement for parents seeking solutions-- Follow us on Socials: Instagram: @pxdocs Facebook: Dr. Tony Ebel & The PX Docs Network Youtube: The PX Docs For more information, visit PXDocs.com to read informative articles about the power of Neurologically-Focused Chiropractic Care. Find a PX Doc Office near me: PX DOCS DirectoryTo watch Dr. Tony's 30 min Perfect Storm Webinar: Click HereSubscribe, share, and stay tuned for more incredible episodes unpacking the power of Nervous System focused care for children!

There's growing concern about microplastics and how they impact our health...     And new research is showing something even more alarming—our brain tissue may contain 10 times more microplastics than any other organ!     These microscopic plastic particles are everywhere—in our food, water, and even the air we breathe.     So on today's Cabral Concept 3310, I'll take you through the latest research on microplastics, how they're affecting our brain and overall health, and most importantly, what we can do to reduce our exposure. Enjoy the show and let me know your thoughts!   - - - For Everything Mentioned In Today's Show: StephenCabral.com/3310 - - - Get a FREE Copy of Dr. Cabral's Book: The Rain Barrel Effect - - - Join the Community & Get Your Questions Answered: CabralSupportGroup.com - - - Dr. Cabral's Most Popular At-Home Lab Tests: > Complete Minerals & Metals Test (Test for mineral imbalances & heavy metal toxicity) - - - > Complete Candida, Metabolic & Vitamins Test (Test for 75 biomarkers including yeast & bacterial gut overgrowth, as well as vitamin levels) - - - > Complete Stress, Mood & Metabolism Test (Discover your complete thyroid, adrenal, hormone, vitamin D & insulin levels) - - - > Complete Food Sensitivity Test (Find out your hidden food sensitivities) - - - > Complete Omega-3 & Inflammation Test (Discover your levels of inflammation related to your omega-6 to omega-3 levels) - - - Get Your Question Answered On An Upcoming HouseCall: StephenCabral.com/askcabral - - - Would You Take 30 Seconds To Rate & Review The Cabral Concept? The best way to help me spread our mission of true natural health is to pass on the good word, and I read and appreciate every review!  

Another Weird Wednesday episode. Today we are reanimating life as scientists successfully revive brain tissue, and a 46,000-year-old worm comes back to the world of the living. Plus, we learn what mummies smelled like. On This Day in History, the Catholic Church bans Galileo from teaching his theory that the Earth rotates around the sun. Scientists Successfully Revived Brain Tissue from Suspended Animation | Popular Mechanics Mouse Brain Slices Were Frozen For A Week, Brought Back To Life | BroBible Frozen worm comes back to life after 46,000 years - Earth.com A worm has been revived after 46,000 years in the Siberian permafrost | CNN A novel nematode species from the Siberian permafrost shares adaptive mechanisms for cryptobiotic survival with C. elegans dauer larva | PLOS Genetics Ancient Egyptian mummies smell 'sweet' and 'spicy', researchers say | Offbeat News | Sky News What Does a Mummy Smell Like? Scientists Uncover Surprising Truth | SciTechDaily The truth about Galileo and his conflict with the Catholic Church | UCLA Contact the show - coolstuffcommute@gmail.com Learn more about your ad choices. Visit megaphone.fm/adchoices

Here is a PG-13 rated description of the National Institute of Health, Francis Collins, and human fetal tissue experimentation conducted over years. Why would a theistic evolutionist and an evangelical endorse the use of human fetal tissue for these experiments? Francis Collins definition of truth is neither biblical or scientific, yet he was heavily endorsed by evangelical ministries. This program includes: 1. The World View in 5 Minutes with Adam McManus (Modern-day Jonah story, 16 million Americans between 110 & 369 years old getting SSI checks?, British Prime Minister willing to put British troops in Ukraine) 2. Generations with Kevin Swanson