Podcasts about vectors

Time for the table of sexuation, y'all! And within it, as the title of this episode indicates, “Vectors of Sexuation.” You can also access the video recording of this lecture at our YouTube channel. And if you're eager for more, join our series on Seminar XXI! This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit lecturesonlacan.substack.com

Brenden Matthews, a seasoned software engineer, entrepreneur, and author of the Idiomatic Rust and Code Like a Pro in Rust books (both from Manning), speaks with SE Radio host Gavin Henry about Idiomatic Rust. They start with a look at what "idiomatic" means, and then discuss Generics, Traits, common design patterns you'll see in well written Rust code, and anti-patterns to avoid. Matthews suggests some tools that can help you immediately write idiomatic Rust, as well as what building blocks can also help. This episode examines what Generics are and how they compare to other languages, as well as what Traits are, how macros help, what a Fluent Interface is, and why unwrap() is bad. They also discuss what code smells to look out for, Clone, Copy, and a really nice place to go read real-world Idiomatic Rust code. Brought to you by IEEE Computer Society and IEEE Software magazine.

This week we discuss vectors in a hotter world.   Vector-borne diseases, which are transmitted by hematophagous arthropods such as mosquitoes, ticks, and sandflies, pose a significant burden on global public health. These diseases disproportionately affect populations in tropical and subtropical regions, where environmental conditions favor the survival and proliferation of vectors. Given that vectors are ectothermic organisms, their life cycles, reproduction, survival rates, and geographic distribution are heavily influenced by climate variables such as temperature, rainfall, and humidity. Consequently, changes in climate patterns can have profound effects on the transmission dynamics of vector-borne diseases, altering their geographic spread and intensity. Rising global temperatures have led to the expansion of vector habitats into previously unsuitable regions, including temperate zones. Warmer climates accelerate the development of many vectors and pathogens, reducing the extrinsic incubation period of viruses such as dengue, Zika, and chikungunya. Additionally, increased temperatures can extend the breeding season of mosquitoes like Aedes aegypti and Anopheles species, enhancing their capacity to transmit diseases such as malaria. Conversely, extreme heat events may reduce vector survival in some regions, leading to localized declines in transmission. ​Changes in precipitation patterns also play a crucial role in shaping vector distribution. Heavy rainfall events can create new breeding sites for mosquitoes by increasing the availability of stagnant water, while drought conditions may drive vectors closer to human settlements in search of water sources. In particular, shifts in rainfall patterns have been linked to outbreaks of malaria, dengue, and West Nile virus in various parts of the world. Increased humidity can further facilitate the survival of certain pathogens within vectors, enhancing their ability to transmit infections. Beyond climate variables, other anthropogenic factors contribute to the spread of vector-borne diseases. Land use changes, such as deforestation and urbanization, have disrupted natural ecosystems, bringing vectors and humans into closer contact. For example, deforestation in the Amazon has been associated with increased malaria transmission due to the creation of new breeding sites for Anopheles mosquitoes. Similarly, expanding urban populations with inadequate water management systems provide ideal conditions for the proliferation of Aedes mosquitoes, driving the rise in dengue and chikungunya cases. Globalization and human mobility further compound the issue by facilitating the movement of infected individuals and vectors across borders. Increased travel and trade have contributed to the introduction and establishment of vector-borne diseases in regions where they were previously rare. For instance, the spread of Aedes albopictus, a competent vector for dengue and chikungunya, has been linked to international trade in used tires and lucky bamboo plants, which serve as breeding grounds during transport. The multifaceted relationship between climate change and vector-borne diseases presents a challenge for public health interventions. While climate factors influence vector dynamics, their impact is often modulated by socio-economic conditions, infrastructure, and public health responses. To mitigate the growing threat of vector-borne diseases, an integrated approach is necessary—combining climate adaptation strategies, vector control measures, surveillance programs, and community engagement. Recent research underscores the importance of predictive modeling to anticipate outbreaks and inform public health policies. Advances in remote sensing, artificial intelligence, and climate modeling are enabling researchers to identify high-risk areas and implement targeted interventions. Strengthening early warning systems and investing in sustainable vector control strategies, such as genetically modified mosquitoes and Wolbachia-infected mosquito programs, offer promising avenues for reducing disease transmission. In conclusion, while climate change is reshaping the global landscape of vector-borne diseases, its effects are complex and intertwined with other environmental and societal factors. Understanding these dynamics is crucial for developing proactive strategies to mitigate the risks associated with the redistribution of vectors and the spread of diseases worldwide. By integrating climate science, epidemiology, and public health measures, we can better prepare for emerging threats and protect vulnerable populations from the growing impact of vector-borne diseases.  

MAKE HISTORY WITH US THIS SUMMER:https://demystifysci.com/demysticon-2025PATREON https://www.patreon.com/c/demystifysciPARADIGM DRIFThttps://demystifysci.com/paradigm-drift-showPATREON: get episodes early + join our weekly Patron Chat https://bit.ly/3lcAasBMERCH: Rock some DemystifySci gear : https://demystifysci.myspreadshop.com/allAMAZON: Do your shopping through this link: https://amzn.to/3YyoT98SUBSTACK: https://substack.com/@UCqV4_7i9h1_V7hY48eZZSLw@demystifysciAndrew Cutler is the author of the Vectors of Mind Substack, where he explores the question of how humans became… human. His research starts from a simple premise - if our self-awareness, the ability to look at ourselves in the mirror and declare that there is an “I” staring back, is truly unique in the animal kingdom, then it likely related to that moment of coming. But no one really knows what happened in the fog of pre-history to ratchet us from the gauzy time before we were fully human to… whatever all of this that we're living in right now could be called. In fact, this is often referred to as the sapient paradox. Why, oh why, did we become genetically modern nearly 300,000 years ago (maybe more) but take until about 50,000 years ago to start doing human things like making art, ritually burying our dead, and tracking the stars? Many have suggested it was psychedelic mushrooms that pushed us over the edge. This is the stoned ape hypothesis, which says that a sufficiently large psychedelic experience pushed us out of the womb of the earth. However, Andrew thinks it might have been something else. He figures it was snakes. And women. Together, they produced the Snake Cult of Consciousness that dragged us, kicking and screaming, into the world.(00:00) Go! (00:06:56) The Sapient Paradox Explored(00:13:09) Recursion and Human Cognition(00:19:22) Abstraction and Innovation(00:25:23) Self-awareness Evolution(00:27:14) Recursion and Strategy(00:30:00) Cultural Shifts and Domination(00:33:39) Origins of Recursion(00:38:22) Subject-Object Separation(00:47:34) Linguistic Evolution(00:48:56) Emotional Intelligence in Animals(00:50:33) Creation Myths and Self-Awareness(00:52:10) Awareness of Death in Animals(00:56:06) Evolution of Symbolic Thought(01:00:58) Göbekli Tepe and Diffusion Hypotheses(01:06:05) Matriarchy and Rituals in Early Cultures(01:08:44) Human Migration and Cultural Development(01:17:11) Origins of Human Consciousness and Language(01:25:09) Snakes, Myths, and Early Civilization(01:33:40) Women, Mythology, and Historical Narratives(01:36:30) The Subtle Female Power Dynamics in Patriarchal Societies(01:40:25) Evolution of Societal Structures(01:46:00) Neolithic Genetic Bottleneck and Patriarchal Theories(01:49:23) Women's Role in Human Cognitive Evolution(01:56:11) Symbolism of Snakes and Ancient Knowledge(02:02:10) Snake Venom Usage(02:07:12) Historical Cults and Rituals(02:11:07) Greek Tragedy and Mystery Cults(02:14:08) Matriarchy and Cultural Myths(02:17:10) Diffusion of Culture and Legends(02:22:36) Comparative Mythology and the Seven Sisters Myth(02:27:01) Scientific and Metaphysical Connections in Human Origin Stories(02:28:55) The Origins and Significance of Gospel Stories(02:30:03) Shamanistic Cults and Cultural Symbols in Ancient Sites #HumanOrigins, #AncientHistory, #Mythology, #Evolution, #Consciousness, #AncientMysteries, #Symbolism, #SelfAwareness, #HumanEvolution, #AncientCultures, #CognitiveScience, #SpiritualEvolution, #Anthropology, #Philosophy, #AncientWisdom, #Archaeology, #philosophypodcast, #sciencepodcast, #longformpodcast

The Department of the Air Force faces a crisis. Decades' worth of insufficient budgets has slowed essential modernization, necessary capacity and key personnel investments. Air Force and Space Force leaders have warned of these risks for years. However, resource decisions were largely out of their control. As a result, the U.S. Air Force now operates the oldest and smallest aircraft inventory in its history. Combined with a lack of spare parts, an enduring pilot shortage, and falling pilot experience levels, the Air Force finds itself in a precarious condition that portends a national security disaster. The U.S. Space Force, meanwhile, is struggling to meet growing demand for the essential capabilities it provides. One of the biggest challenges: scale. The Space Force is constrained by its size and must grow as rapidly as possible. The cost to recover the Air Force's decline and adequately fund the growth of the Space Force will require an increase of at least $45 billion annually for at least the next five years. The Department of the Air Force underpins and enables warfare in every domain, not just air and space. Prioritizing these capabilities can help the Trump defense team achieve its objective of “pursue peace through strength” but doing so requires a new way of doing business and in particular not the conventional stove-piped, “salami slice” budget cutting approach. Using cost-per-effect assessments to make optimal decisions, the new administration can achieve the best use of the nation's resources. There is no time left to delay reversing the Department of the Air Force's current course. The fixes must start now, or the United States risks losing the next major war.

2020 BOOTLESS PANDEMIC PANIC ON THE THEODORE ROOSEVELT.  4/4: Vectors: Heroes, Villains, and Heartbreak on the Bridge of the U.S. Navy by  Thomas B. Modly  (Author) https://www.amazon.com/Vectors-Heroes-Villains-Heartbreak-Bridge/dp/1642257036 Thomas Modly had an eclectic career in the military, academia, business, and government when he answered the call to service in 2017 and returned to the Navy where his career began. His experience, as chronicled in these pages, tells the story of Secretary Modly's quest to advance the Department of the Navy's preparedness for the challenges of this century. As Acting Secretary of the Navy he held fast to the mantra of “acting, not pretending,” and thus advocated aggressively for the Navy and Marine Corps' future ― a future he believed would be defined by uncertainty and unpredictability. Every Friday he wrote a personal message to the entire Department regardless of rank. Those messages were called SECNAV Vectors. Each Vector was intended to clearly communicate his priorities and to establish a rapport with all levels of the organization. The subject of each Vector was inspired by real events that occurred in real time. As these events unfolded , the Secretary's unyielding emphasis on being prepared for unpredictable events are proven to be prescient as the Navy found itself, unintentionally, in the center of COVID-19 crisis. 1941 California burning and sinking

 Preview: Former Acting Navy Secretary Tom Modly's "Vectors" Recounts the 2020 COVID Panic Aboard USS Theodore Roosevelt. More Later. 1936 Ranger, Lexington, Saratoga

2020 BOOTLESS PANDEMIC PANIC ON THE THEODORE ROOSEVELT.  1/4: Vectors: Heroes, Villains, and Heartbreak on the Bridge of the U.S. Navy by  Thomas B. Modly  (Author) https://www.amazon.com/Vectors-Heroes-Villains-Heartbreak-Bridge/dp/1642257036 Thomas Modly had an eclectic career in the military, academia, business, and government when he answered the call to service in 2017 and returned to the Navy where his career began. His experience, as chronicled in these pages, tells the story of Secretary Modly's quest to advance the Department of the Navy's preparedness for the challenges of this century. As Acting Secretary of the Navy he held fast to the mantra of “acting, not pretending,” and thus advocated aggressively for the Navy and Marine Corps' future ― a future he believed would be defined by uncertainty and unpredictability. Every Friday he wrote a personal message to the entire Department regardless of rank. Those messages were called SECNAV Vectors. Each Vector was intended to clearly communicate his priorities and to establish a rapport with all levels of the organization. The subject of each Vector was inspired by real events that occurred in real time. As these events unfolded , the Secretary's unyielding emphasis on being prepared for unpredictable events are proven to be prescient as the Navy found itself, unintentionally, in the center of COVID-19 crisis. 1918 Battle of the Falklands

2020 BOOTLESS PANDEMIC PANIC ON THE THEODORE ROOSEVELT.  2/4: Vectors: Heroes, Villains, and Heartbreak on the Bridge of the U.S. Navy by  Thomas B. Modly  (Author) https://www.amazon.com/Vectors-Heroes-Villains-Heartbreak-Bridge/dp/1642257036 Thomas Modly had an eclectic career in the military, academia, business, and government when he answered the call to service in 2017 and returned to the Navy where his career began. His experience, as chronicled in these pages, tells the story of Secretary Modly's quest to advance the Department of the Navy's preparedness for the challenges of this century. As Acting Secretary of the Navy he held fast to the mantra of “acting, not pretending,” and thus advocated aggressively for the Navy and Marine Corps' future ― a future he believed would be defined by uncertainty and unpredictability. Every Friday he wrote a personal message to the entire Department regardless of rank. Those messages were called SECNAV Vectors. Each Vector was intended to clearly communicate his priorities and to establish a rapport with all levels of the organization. The subject of each Vector was inspired by real events that occurred in real time. As these events unfolded , the Secretary's unyielding emphasis on being prepared for unpredictable events are proven to be prescient as the Navy found itself, unintentionally, in the center of COVID-19 crisis. 1941 Hickam Field, Pearl Harbor

2020 BOOTLESS PANDEMIC PANIC ON THE THEODORE ROOSEVELT.  3/4: Vectors: Heroes, Villains, and Heartbreak on the Bridge of the U.S. Navy by  Thomas B. Modly  (Author) https://www.amazon.com/Vectors-Heroes-Villains-Heartbreak-Bridge/dp/1642257036 Thomas Modly had an eclectic career in the military, academia, business, and government when he answered the call to service in 2017 and returned to the Navy where his career began. His experience, as chronicled in these pages, tells the story of Secretary Modly's quest to advance the Department of the Navy's preparedness for the challenges of this century. As Acting Secretary of the Navy he held fast to the mantra of “acting, not pretending,” and thus advocated aggressively for the Navy and Marine Corps' future ― a future he believed would be defined by uncertainty and unpredictability. Every Friday he wrote a personal message to the entire Department regardless of rank. Those messages were called SECNAV Vectors. Each Vector was intended to clearly communicate his priorities and to establish a rapport with all levels of the organization. The subject of each Vector was inspired by real events that occurred in real time. As these events unfolded , the Secretary's unyielding emphasis on being prepared for unpredictable events are proven to be prescient as the Navy found itself, unintentionally, in the center of COVID-19 crisis. 1904 Battle of Port Arthur

Authors and creators will discuss the role of TV in society historically and today, including connections to politics, queer spectatorship, and representations of race, class, and gender. David Craig is a Clinical Professor of Communication and director of the Global Media and Communication program at USC. An expert in Hollywood, Chinese, and social media industries; a television historian; an Emmy-nominated producer and television executive; and a pioneer in the field of Creator Studies at USC Annenberg School for Communication and Journalism, his most recent books is Apocalypse Television How The Day After Helped End the Cold War. Anthony Sparks is showrunner, head writer, and executive producer of the TV drama, Queen Sugar, created by Ava DuVernay and executive produced by Oprah Winfrey and writer/producer for the Iron Mike series on Hulu. A former cast member of Broadway hit STOMP, he holds three degrees from USC (BFA, MA, and Ph.D.), where he studied Theatre, Film, Anthropology, and American History. Karen Tongson is the author of Normporn: Queer Viewers and the TV That Soothes Us, Why Karen Carpenter Matters (one of Pitchfork's best music books of 2019), and Relocations: Queer Suburban Imaginaries. In 2019, she was awarded Lambda Literary's Jeanne Cordova Prize for Lesbian/Queer Nonfiction. She directs the Mellon-funded Consortium for Gender, Sexuality, Race, and Public Culture at USC, where she is also Chair and professor of Gender and Sexuality Studies and professor of English and American Studies and Ethnicity.  Moderator: Tara McPherson is the HMH Foundation Endowed Professor at the USC School of Cinematic Arts and director of the Sidney Harman Academy for Polymathic Study. She is author of Feminist in a Software Lab and Reconstructing Dixie, co-editor of Hop on Pop and Transmedia Frictions, and editor of Digital Youth, Innovation and the Unexpected. She was founding editor of the pioneering multimedia journal Vectors and the lead PI of the online platform Scalar. She has received funding from the Mellon, Ford, Annenberg, and MacArthur foundations, as well as from the NEH.

a biting insect or tick, that transmits a pathogen, disease or parasite from an infected animal to a human

Episode 101: In this episode of Critical Thinking - Bug Bounty Podcast we've been hijacked! Rez0 takes control of this episode, and sits down with Johann Rehberger to discuss the intricacies of AI application vulnerabilities. They talk through the importance of understanding system prompts, and various obfuscation techniques used to bypass security measures, the best AI platforms, and the evolving landscape of AI security.Follow us on twitter at: @ctbbpodcastWe're new to this podcasting thing, so feel free to send us any feedback here: info@criticalthinkingpodcast.ioShoutout to YTCracker for the awesome intro music!------ Links ------Follow your hosts Rhynorater & Teknogeek on twitter:https://twitter.com/0xteknogeekhttps://twitter.com/rhynorater------ Ways to Support CTBBPodcast ------Hop on the CTBB Discord at https://ctbb.show/discord!We also do Discord subs at $25, $10, and $5 - premium subscribers get access to private masterclasses, exploits, tools, scripts, un-redacted bug reports, etc.Today's Sponsor - ThreatLocker. Check out their Elevation Control! https://www.criticalthinkingpodcast.io/tl-ecToday's Guest: https://x.com/wunderwuzzi23ResourcesJohann's bloghttps://embracethered.com/blog/zombaishttps://embracethered.com/blog/posts/2024/claude-computer-use-c2-the-zombais-are-coming/Copiratehttps://embracethered.com/blog/posts/2024/m365-copilot-prompt-injection-tool-invocation-and-data-exfil-using-ascii-smuggling/Timestamps(00:00:00) Introduction(00:01:59) Biggest things to look for in AI hacking(00:11:58) Best AI companies to hack on(00:15:59) URL Redirects and Obfuscation Techniques(00:24:05) Copirate(00:35:50) prompt injection guardrails and threats

Send us a textFull episodes are available to paid subscribers on the M&M Substack and free on YouTube. This is a free, partial version.About the guest: Andrew Cutler, PhD is a machine learning engineer who has studied natural language processing, psychometrics & personality using quantitative methods. He writes about the origins of consciousness on his Substack, "Vectors of Mind"Episode summary: Nick and Dr. Cutler discuss: language & recursion; human evolution & the origins of "higher" consciousness; symbolic cognition, social intelligence & metacognition; creation myths & ritual cults throughout history; snake cults in human history; the intentional ingestion of snake venom in the present-day; the "Stone Ape Theory" of consciousness; the origins of civilization; and more.Related episodes:M&M #141: Evolution, Language, Domestication, Symbolic Cognition, AI & Large Language Models | Terrence DeaconM&M #1: Psychedelics, Civilization, Religion, Death & Plant Medicine | Brian MurareskuSpecial offer: Use MINDMATTERSPECIAL2 to get a free 1-year premium subscription to Consensus, a new AI-powered research tool to help you find the best science, faster ($150 value, limited time offer).*This content is never meant to serve as medical adviceSupport the showAll episodes (audio & video), show notes, transcripts, and more at the M&M Substack Affiliates: MASA Chips—delicious tortilla chips made from organic corn and grass-fed beef tallow. No seed oils or artificial ingredients. Use code MIND for 20% off. KetoCitra—Ketone body BHB with potassium, calcium & magnesium, formulated with kidney health in mind. Use code MIND20 for 20% off. Lumen device to optimize your metabolism for weight loss or athletic performance. Use code MIND for 10% off. Athletic Greens: Comprehensive & convenient daily nutrition. Free 1-year supply of vitamin D with purchase. Consensus: AI-powered academic research tool. Find & understand the best science, faster. Free 1-year premium sub with code MINDMATTERSPECIAL (exp 12.10.24) Learn all the ways you can support my efforts...

We'll discuss a recent client case study, offering insights into long-term strategic planning and the importance of balancing stress with adaptability. Alex and Chris will break down the nuances of athlete assessment, exercise classification, and the often-overlooked force vectors crucial for effective training. They'll also touch on innovative tool development for coaches, highlighting their commitment to continuous education and the integration of kinematic and kinetic analyses into exercise selection. Prepare for a deep dive into the principles of dynamic correspondence, the hierarchy of interventions, and the intricate balance between conditioning and specific preparatory exercises. Whether you're a coach, athlete, or fitness enthusiast, this episode promises to provide valuable takeaways on optimizing performance and achieving resilience. Stay tuned!

Mark Kirstein, Chief Product Officer at DropSuite discusses the evolving cyber threat landscape, particularly how SMBs are increasingly targeted by cybercriminals. He explains the rising importance of data protection and the critical role MSPs play in helping small businesses safeguard essential information. Mark shares insights on new attack vectors, the impact of AI on cyber threats, and key best practices for cybersecurity. Tune in to discover strategies that ensure resilience and continuity for businesses of all sizes.

In this previous episode of Final Settlement, I joined the show to tackle custodial threat vectors and the security challenges unique to Bitcoin. We discussed Bitcoin as apolitical money and its role as a digital bearer instrument, which brings with it the complex issue of secure custody. I shared insights from a recent personal security incident when my room was broken into at a Bitcoin conference in Lugano, underscoring the very real risks we face. We explored the evolution of Bitcoin custody, the importance of multisig setups, and the approach of Onramp's Multi-Institution Custody in mitigating custodial threats. Raising awareness about these risks is essential, and this conversation offered important takeaways for anyone looking to secure their Bitcoin. It's a crucial discussion worth revisiting as the industry continues to grow. Link to original episode: Final Settlement E016: Assessing Custodial Threat Vectors with Guy Swann (Link: https://tinyurl.com/3be22hjw) Guest Links: Onramp on X (Link: https://x.com/onrampbitcoin) Onramo Website (Link: https://onrampbitcoin.com/) Host Links ⁠Guy on Nostr ⁠(Link: http://tinyurl.com/2xc96ney) ⁠Guy on X ⁠(Link: https://twitter.com/theguyswann) Guy on Instagram (Link: https://www.instagram.com/theguyswann) Guy on TikTok (Link: https://www.tiktok.com/@theguyswann) Guy on YouTube (Link: https://www.youtube.com/@theguyswann) ⁠Bitcoin Audible on X⁠ (Link: https://twitter.com/BitcoinAudible) The Guy Swann Network Broadcast Room on Keet (Link: https://tinyurl.com/3na6v839) Check out our awesome sponsors!   Get ⁠5% off the COLDCARD⁠ with code BITCOINAUDIBLE ⁠⁠⁠⁠⁠⁠(Link: https://bitcoinaudible.com/coldcard) Trying to BUY BITCOIN? River, secure, trusted, bitcoin only, lightning enabled, simple. (Link: https://bitcoinaudible.com/river) Swan⁠: The best way to buy, learn, and earn #Bitcoin (Link: https://swanbitcoin.com) Bitcoin Games! Get 10% off the best Bitcoin board game in the world, HODLUP! Or any of the other great games from the Free Market Kids! Use code GUY10 at checkout for 10% off your cart! (Link: https://www.freemarketkids.com/collections/games-1) Bitcoin Custodial Multisig Want to get into Bitcoin but not ready for self custody? Use custodial multisig for the best way to distribute trust across multiple institutions and even jurisdictions! Check out OnRamp. (Link: BitcoinAudible.com/onramp) Education & HomeSchooling Get the lesson in real economics that you never got in school, and teach your kids the truth, not the st...

Connect with the Onramp team Apolitical Money Bitcoin Audible Guy Swann on X Guy's Take E093 Final Settlement: a biweekly podcast presented by Onramp which explores the breadth and depth of the Bitcoin thesis, focusing on the underlying mechanics of the protocol, its ongoing development, and real-world applications of the technology. Hosted by Brian Cubellis (Chief Strategy Officer at Onramp) and Michael Tanguma (Co-founder & CEO of Onramp), Final Settlement aims to go beyond the conventional view of Bitcoin as merely a financial asset, or “digital gold." Discover how this groundbreaking technology has the potential to benefit society through rearchitecting how value is stored and transferred. A resource for institutional investors and bitcoin enthusiasts alike, our discussions aim to enhance your understanding and conviction in Bitcoin's broader utility – tune in to grasp the full scope of bitcoin's transformative power in the digital age. 00:00-Welcoming Guy Swann 01:55-Bitcoin as apolitical money 13:02-A message from Onramp 14:10-Bitcoin is a digital bearer instrument 23:13-Multisig & the evolution of bitcoin custody 34:50-Lessons from a security incident in Lugano 45:10-Onramp Multi-Institution Custody 46:38-Assessing custodial threat vectors 01:07:12-Raising awareness about security 01:15:23-Outro Please subscribe to Onramp Media channels and sign up for Research & Insights to get access to the best content in the ecosystem weekly.

Summary The written word dominates EA discourse but visuals have a unique power in communicating ideas that seems quite underleveraged in this community. As a designer and communicator in the space, I wanted to share some of the presentations and visualizations I've created over the years in hopes that they might be helpful to others. My goal isn't to present these visuals as "ready-to-use" resources—for various reasons they're not ready (see disclaimers)—but rather as references that hopefully inspire others to create and invest in visual forms of communication. Effective Giving 101 (2023) In 2023, when I was director of design at Giving What We Can, we were invited to give a talk at Microsoft about effective giving. We normally don't dive so deep into the research that undergirds our recommendations but—given the highly-educated, highly-analytical audience at Microsoft—I thought it could be compelling to actually get into the weeds and [...] ---Outline:(00:16) Summary(00:50) Effective Giving 101 (2023)(01:53) Full deck: Doing Good Better (Microsoft 2023)(02:00) GiveWell's 2020 analysis of AMF(02:58) Slides: GiveWell's 2020 analysis of AMF(03:15) Global income illustration(04:53) Slides: The Global Income Distribution(05:09) Prioritization in GCR (2024)(05:56) Parfit's 99% extinction hypothetical(06:56) Slides: Parfit's 99% v 100%(07:13) Mapping the GCR landscape(08:54) Slides: Visualizing: The GCR Landscape(09:13) Bonus: Effective Giving Strategy Frameworks(10:20) Vision to Vectors(10:23) Slides: Vision to Vectors(10:39) The Pledger Journey(10:42) Slides: The Pledger JourneyThe original text contained 8 images which were described by AI. --- First published: October 31st, 2024 Source: https://forum.effectivealtruism.org/posts/GuFxEPcn7rzz4pDhw/visualizing-ea-ideas --- Narrated by TYPE III AUDIO. ---Images from the article:Apple Podcasts and Spotify do not show images in the episode description. Try Pocket Casts, or another podcast app.

This week, Lois Houston and Nikita Abraham continue their exploration of Oracle AI Vector Search with a deep dive into vector indexes and memory considerations.   Senior Principal APEX and Apps Dev Instructor Brent Dayley breaks down what vector indexes are, how they enhance the efficiency of search queries, and the different types supported by Oracle AI Vector Search.   Oracle Database 23ai: Oracle AI Vector Search Fundamentals: https://mylearn.oracle.com/ou/course/oracle-database-23ai-oracle-ai-vector-search-fundamentals/140188/   Oracle University Learning Community: https://education.oracle.com/ou-community   LinkedIn: https://www.linkedin.com/showcase/oracle-university/   Twitter: https://twitter.com/Oracle_Edu   Special thanks to Arijit Ghosh, David Wright, Radhika Banka, and the OU Studio Team for helping us create this episode.   --------------------------------------------------------   Episode Transcript:   00:00 Welcome to the Oracle University Podcast, the first stop on your cloud journey. During this series of informative podcasts, we'll bring you foundational training on the most popular Oracle technologies. Let's get started!   00:26 Nikita: Welcome back to the Oracle University Podcast! I'm Nikita Abraham, Team Lead of Editorial Services at Oracle University, and with me is Lois Houston, Director of Innovation Programs. Lois: Hi everyone! Last week was Part 1 of our discussion on Oracle AI Vector Search. We talked about what it is, its benefits, the new vector data type, vector embedding models, and the overall workflow. In Part 2, we're going to focus on vector indices and memory. 00:56 Nikita: And to help us break it all down, we've got Brent Dayley back with us. Brent is a Senior Principal APEX and Apps Dev Instructor with Oracle University. Hi Brent! Thanks for being with us today. So, let's jump right in! What are vector indexes and how are they useful? Brent: Now, vector indexes are specialized indexing data structures that can make your queries more efficient against your vectors. They use techniques such as clustering, and partitioning, and neighbor graphs. Now, they greatly reduce the search space, which means that your queries happen quicker. They're also extremely efficient. They do require that you enable the vector pool in the SGA. 01:42 Lois: Brent, walk us through the different types of vector indices that are supported by Oracle AI Vector Search. How do they integrate into the overall process? Brent: So Oracle AI Vector Search supports two types of indexes, in-memory neighbor graph vector index. HNSW is the only type of in-memory neighbor graph vector index that is supported. These are very efficient indexes for vector approximate similarity search. HNSW graphs are structured using principles from small world networks along with layered hierarchical organization. And neighbor partition vector index, inverted file flat index, is the only type of neighbor partition index supported. It is a partition-based index which balances high search quality with reasonable speed. 02:35 Nikita: Brent, you mentioned that enabling the vector pool in the SGA is a requirement when working with vector indexes. Can you explain that process for us? Brent: In order for you to be able to use vector indexes, you do need to enable the vector pool area. And in order to do that, what you need to do is set the vector memory size parameter. You can set it at the container database level. And the PDB inherits it from the CDB. Now bear in mind that the database does have to be balanced when you set the vector pool. 03:12 Lois: Ok. Are there any other considerations to keep in mind when using vector indices? Brent: Vector indexes are stored in this pool, and vector metadata is also stored here. And you do need to restart the database. So large vector indexes do need lots of RAM, and RAM constrains the vector index size. You should use IVF indexes when there is not enough RAM. IVF indexes use both the buffer cache as well as disk. 03:42 Nikita: And what about memory considerations? Brent: So to remind you, a vector is a numerical representation of text, images, audio, or video that encodes the features or semantic meaning of the data, instead of the actual contents, such as the words or pixels of an image. So the vector is a list of numerical values known as dimensions with a specified format. Now, Oracle does support the int8 format, the float32 format, and the float64 format. Depending on the format depends on the number of bytes. For instance, int8 is one byte, float32 is four bytes. Now, Oracle AI Vector Search supports vectors with up to 65,535 dimensions. 04:34 Lois: What should we know about creating a table with a vector column? Brent: Now, Oracle Database 23ai does have a new vector data type. The new data type was created in order to support vector search. The definition can include the number of dimensions and can include the format. Bear in mind that either one of those are optional when you define your column. The possible dimension formats are int, float 32, and float 64. Float 32 and float 64 are IEEE standards, and Oracle Database will automatically cast the value if needed. 05:18 Nikita: Can you give us a few declaration examples? Brent: Now, if we just do a vector type, then the vectors can have any arbitrary number of dimensions and formats. If we describe the vector type as vector * , *, then that means that vectors can have an arbitrary number of dimensions and formats. Vector and vector * , * are equivalent. Vector with the number of dimensions specified, followed by a comma, and then an asterisk, is equivalent to vector number of dimensions. Vectors must all have the specified number of dimensions, or an error will be thrown. Every vector will have its dimension stored without format modification. And if we do vector asterisk common dimension element format, what that means is that vectors can have an arbitrary number of dimensions, but their format will be up-converted or down-converted to the specified dimension element format, either INT8, float 32, or float 64. 06:25 Working towards an Oracle Certification this year? Take advantage of the Certification Prep live events in the Oracle University Learning Community. Get tips from OU experts and hear from others who have already taken their certifications. Once you're certified, you'll gain access to an exclusive forum for Oracle-certified users. What are you waiting for? Visit mylearn.oracle.com to get started.   06:52 Nikita: Welcome back! Brent, what is the vector constructor and why is it useful? Brent: Now, the vector constructor is a function that allows us to create vectors without having to store those in a column in a table. These are useful for learning purposes. You use these usually with a smaller number of dimensions. Bear in mind that most embedding models can contain thousands of different dimensions. You get to specify the vector values, and they usually represent two-dimensional like xy coordinates. The dimensions are optional, and the format is optional as well. 07:29 Lois: Right. Before we wrap up, can you tell us how to calculate vector distances? Brent: Now, vector distance uses the function VECTOR_DISTANCE as the main function. This allows you to calculate distances between two vectors and, therefore, takes two vectors as parameters. Optionally, you can specify a metric. If you do not specify a metric, then the default metric, COSINE, would be used. You can optionally use other shorthand functions, too. These include L1 distance, L2 distance, cosine distance, and inner product. All of these functions also take two vectors as input and return the distance between them. Now the VECTOR_DISTANCE function can be used to perform a similarity search. If a similarity search query does not specify a distance metric, then the default cosine metric will be used for both exact and approximate searches. If a similarity search does specify a distance metric in the VECTOR_DISTANCE function, then an exact search with that distance metric is used if it conflicts with the distance metric specified in a vector index. If the two distance metrics are the same, then this will be used for both exact as well as approximate searches. 08:58 Nikita: I was wondering Brent, what vector distance metrics do we have access to? Brent: We have Euclidean and Euclidean squared distances. We have cosine similarity, dot product similarity, Manhattan distance, and Hamming similarity. Let's take a closer look at the first of these metrics, Euclidean and Euclidean squared distances. This gives us the straight-line distance between two vectors. It does use the Pythagorean theorem. It is sensitive to both the vector size as well as the direction. With Euclidean distances, comparing squared distances is equivalent to comparing distances. So when ordering is more important than the distance values themselves, the squared Euclidean distance is very useful as it is faster to calculate than the Euclidean distance, which avoids the square root calculation. 09:58 Lois: And the cosine similarity metrics? Brent: It is one of the most widely used similarity metrics, especially in natural language processing. The smaller the angle means they are more similar. While cosine distance measures how different two vectors are, cosine similarity measures how similar two vectors are. Dot product similarity allows us to multiply the size of each vector by the cosine of their angle. The corresponding geometrical interpretation of this definition is equivalent to multiplying the size of one of the vectors by the size of the projection of the second vector onto the first one or vice versa. Larger means that they are more similar. Smaller means that they are less similar. Manhattan distance is useful for describing uniform grids. You can imagine yourself walking from point A to point B in a city such as Manhattan. Now, since there are buildings in the way, maybe we need to walk down one street and then turn and walk down the next street in order to get to our result. As you can imagine, this metric is most useful for vectors describing objects on a uniform grid such as city blocks, power grids, or perhaps a chessboard. 11:27 Nikita: And finally, we have Hamming similarity, right? Brent: This describes where vector dimensions differ. They are binary vectors, and it tells us the number of bits that require change to match. It compares the position of each bit in the sequence. Now, these are usually used in order to detect network errors. 11:53 Nikita: Brent, thanks for joining us these last two weeks and explaining what Oracle AI Vector Search is. If you want to learn more about what we discussed today, visit mylearn.oracle.com and search for the Oracle Database 23ai: Oracle AI Vector Search Fundamentals course.   Lois: This concludes our season on Oracle Database 23ai New Features for administrators. In our next episode, we're going to talk about database backup and recovery, but more on that later! Until then, this is Lois Houston… Nikita: And Nikita Abraham signing off! 12:29 That's all for this episode of the Oracle University Podcast. If you enjoyed listening, please click Subscribe to get all the latest episodes. We'd also love it if you would take a moment to rate and review us on your podcast app. See you again on the next episode of the Oracle University Podcast.

It's the Turnipfield Mootlings vs. the Gnarlwood Vectors. With ex-Da Scabby Grindaz star Deg on the Mootlings the team's strategy changes drastically. Will the Mootlings be able to take their new quarterback out of the dregs of the loser's bracket and into the final rounds of the tournament? Thanks to Shayne Plunkett & Jesse Wright of Meadow Vista Media, who created this season's intro theme: www.meadowvistamedia.com Twitter: @MVM_Studio IG: @meadowvistamedia Buy our book, The Ultimate Random Encounters Book: bit.ly/RandomBook Find out more about the show at our website: www.vre.show Show pins and more: shop.vre.show Support us on Patreon: www.patreon.com/VRE Follow us @VRECast

A not so long time ago, in a galaxy not so very for away, The Lads were joined by Kyle Samani, Managing Partner at Multicoin Capitol! Join us for a great discussion on the great Chain Wars, crypto's moneyness, and why Kyle says SOL will flip ETH! Although our guest this week is a Managing Partner of a registered investment adviser, nothing in this podcast should be considered an offer of Multicoin's investment advisory services or should otherwise be confused for investment, tax, legal or other financial advice. In Episode #63 we cover: 00:00 Coming Up on Steady Lads… 02:24 Why SOL Will Flip ETH 16:38 Crypto Moneyness 23:40 Fighting Bitcoin Doesn't Accomplish Anything 35:08 Vectors of Neutrality 42:59 Solana Vs New Chains 48:46 Crypto And The Election 52:06 Pasta of the Week

Speaker Resources:Mod: https://mod.studio/rd/grapho/Michela's NODES 2024 session: https://neo4j.com/nodes2024/agenda/spatial-graph-visualisation-and-storytelling-with-grapho-xr/NeoDash: https://neo4j.com/labs/neodash/Tools of the Month:Google Notebook LM: https://notebooklm.google/HeyGen (AI Digital Avatar): https://www.heygen.comIntelliJ IDEA (IDE for Java development) https://www.jetbrains.com/idea/Announcements / News:Articles:Querying Your Neo4j Aura Database Via HTTPS (Again) https://neo4j.com/developer-blog/query-api-neo4j-aura-https/Neo4j Python Driver 10x Faster With Rust https://neo4j.com/developer-blog/python-driver-10x-faster-with-rust/Hybrid Retrieval for GraphRAG Applications Using the Neo4j GraphRAG Package for Python https://neo4j.com/developer-blog/hybrid-retrieval-neo4j-graphrag-package/Vectors and Graphs: Better Together https://neo4j.com/developer-blog/vectors-graphs-better-together/Knowledge Graphs and LLMs: Fine-Tuning vs. Retrieval-Augmented Generation https://neo4j.com/developer-blog/fine-tuning-vs-rag/Building a Movie Recommendation System With Neo4j https://neo4j.com/developer-blog/movie-recommendation-with-neo4j/GraphRAG Field Guide: Navigating the World of Advanced RAG Patterns https://neo4j.com/developer-blog/graphrag-field-guide-rag-patterns/Spreading the Savings Like Mayo: How Knowledge Graphs Can Transform Invoice Data and Lower Costs https://neo4j.com/developer-blog/spread-savings-like-mayo-knowledge-graphs/Neo4j Takes the Lead: Transforming Graph Database Management With Cypher API Versioning and Database Calendar Versioning https://neo4j.com/developer-blog/neo4j-graph-database-versioning/Modeling Data From the Titanic https://neo4j.com/developer-blog/titanic-data-modeling/Making Relations on the Titanic https://neo4j.com/developer-blog/titanic-relationships/Enhancing Hybrid Retrieval With Graph Traversal Using the Neo4j GraphRAG Package for Python https://neo4j.com/developer-blog/enhance-hybrid-retrieval-neo4j-graphrag-package/Building a GraphRAG Agent With Neo4j and Milvus https://neo4j.com/developer-blog/graphrag-agent-neo4j-milvus/Videos:NODES 2023 playlist https://youtube.com/playlist?list=PL9Hl4pk2FsvUu4hzyhWed8Avu5nSUXYrb&si=8_0sYVRYz8CqqdIcEventsAll Neo4j events: https://neo4j.com/events/(Oct 1) Conference (Denver, CO, USA): Dev2next https://www.dev2next.com/(Oct 14-20) Conference (Sydney, Australia): South by Southwest Sydney https://www.sxswsydney.com/(Oct 16) Conference (London, GB, UK): GraphSummit Europe https://neo4j.com/graphsummit/europe16-17/(Oct 21-25) Conference (San Diego, CA, USA): San Diego Startup Week https://startupsd.org/san-diego-startup-week/(Oct 22) Meetup (New York City, NY, USA): NYJavaSIG https://www.meetup.com/javasig/

This nearly 90-minute conversation was made possible by the open-minded attitude of TrilltheDM, the interest of MercuriousAulicus and Black Lodge Games, and I suppose, the letter X. In it, we discuss Trill's recent video: Mastering Player Choice in Mystery and Horror RPGs and take it further than the original 10-minute runtime would allow, dive into its specific context, and in general have an enjoyable and interesting discussion. You can find the original video at this link: Mastering Player Choice in Mystery & Horror RPGs (youtube.com) This episode appears in its uncut, video form on my YouTube channel and is also re-distributed there in this audio-only version. CONTACT THE SHOW: ⁠⁠E-Mail⁠⁠ ⁠⁠Voice Message⁠⁠ FIND CASTING SHADOWS: ⁠⁠Blog⁠⁠ ⁠⁠Channel⁠⁠ LINKS FROM THIS EPISODE: Mastering Player Choice in Mystery & Horror RPGs - YouTube The Imagination series on the Casting Shadows Podcast Sandboxes: Layers and Vectors of Play: Immersion and Engagement: On Immersion On Attention Imagination and Preparation

In this episode Chet, Romain and Tor chat with Doris Liu from the Compose team about animations in Compose -- covering everything from the basic primitives up to the recently added Shared Element Transitions.   Chapters: Intro (00:00) Animation capabilities of Compose (1:06) Different types of animation specs (3:43) Layers of functionality, transitions (7:49) TargetBasedAnimation (9:48) Vectors & velocity of color change (12:43) Second layer parallel to animation spec (16:39) Animation interruptions (18:48) Motion layout problem-solving (20:19) Both scale and move in question (25:45) Different mental models for layout animation in Compose vs. View (26:20) Shared element (31:05) Are there things you wish more people were aware of? (34:19) What's the tooling story for this? (41:57) What is Look Ahead? (43:16) All software is regret (48:49) New API: Modifier.animateBounds (51:52) How to reach Doris – leave a comment (55:57) Motion Frame of Reference Placement (57:29) Wrap up (59:10) Links: Shared element tutorial → https://goo.gle/3XrGYp5  Shared element talk → https://goo.gle/47tm3qm  A quick guide to compose animations → https://goo.gle/3Tm853p  The API layers except the highest level APIs we chatted about in the podcast → https://goo.gle/3MGsiNE Doris: @doris4lt Romain: @romainguy, threads.net/@romainguy, romainguy@androiddev.social Tor: threads.net/@tor.norbye and tornorbye@androiddev.social Chet: @chethaase, threads.net/@chet.haase, and chethaase@androiddev.social   Catch more Android Developers Backstage on YouTube → https://goo.gle/adb-podcast    Subscribe to Android Developers YouTube → https://goo.gle/AndroidDevs 

Dr. Rodney Rohde returns to the podcast! This time he joins Luis to talk about dengue. You might hear reports about increases in cases in some areas, so it was a good time to talk about it. What is dengue? What type of virus it is? Vectors? Prevention? Is there a vaccine? Tune in to learn more about this virus.Link to Dr. Rohde's dengue article: https://asm.org/articles/2024/august/dengue-is-spreading-is-warmer-weather-to-blameMore information about dengue: https://www.cdc.gov/dengue/index.htmlLink to Dr. Rohde's Podcast: https://www.contagionlive.com/view/from-pathogen-to-infectious-disease-diagnosis-taking-on-potential-standard-of-care-diagnostic-opportunitiesQuestions? Feedback? Send those to letstalkmicro@outlook.comWant to support the podcast? Here's how:Venmo: https://venmo.com/u/letstalkmicroBuy me a Ko-fi: https://ko-fi.com/letstalkmicro

QUESTIONS RAISED RE USINDOPACOM READINESS FOR COMBAT: 1/4: Vectors: Heroes, Villains, and Heartbreak on the Bridge of the U.S. Navy Hardcover – April 4, 2023 by  Thomas B. Modly  (Author) https://www.amazon.com/Vectors-Heroes-Villains-Heartbreak-Bridge/dp/1642257036 Thomas Modly had an eclectic career in the military, academia, business, and government when he answered the call to service in 2017 and returned to the Navy where his career began. His experience, as chronicled in these pages, tells the story of Secretary Modly's quest to advance the Department of the Navy's preparedness for the challenges of this century. As Acting Secretary of the Navy he held fast to the mantra of “acting, not pretending,” and thus advocated aggressively for the Navy and Marine Corps' future ― a future he believed would be defined by uncertainty and unpredictability. Every Friday he wrote a personal message to the entire Department regardless of rank. Those messages were called SECNAV Vectors. Each Vector was intended to clearly communicate his priorities and to establish a rapport with all levels of the organization. The subject of each Vector was inspired by real events that occurred in real time. As these events unfolded , the Secretary's unyielding emphasis on being prepared for unpredictable events are proven to be prescient as the Navy found itself, unintentionally, in the center of COVID-19 crisis. 1939 REUBEN JAMES

QUESTIONS RAISED RE USINDOPACOM READINESS FOR COMBAT: 2/4: Vectors: Heroes, Villains, and Heartbreak on the Bridge of the U.S. Navy Hardcover – April 4, 2023 by  Thomas B. Modly  (Author) https://www.amazon.com/Vectors-Heroes-Villains-Heartbreak-Bridge/dp/1642257036 Thomas Modly had an eclectic career in the military, academia, business, and government when he answered the call to service in 2017 and returned to the Navy where his career began. His experience, as chronicled in these pages, tells the story of Secretary Modly's quest to advance the Department of the Navy's preparedness for the challenges of this century. As Acting Secretary of the Navy he held fast to the mantra of “acting, not pretending,” and thus advocated aggressively for the Navy and Marine Corps' future ― a future he believed would be defined by uncertainty and unpredictability. Every Friday he wrote a personal message to the entire Department regardless of rank. Those messages were called SECNAV Vectors. Each Vector was intended to clearly communicate his priorities and to establish a rapport with all levels of the organization. The subject of each Vector was inspired by real events that occurred in real time. As these events unfolded , the Secretary's unyielding emphasis on being prepared for unpredictable events are proven to be prescient as the Navy found itself, unintentionally, in the center of COVID-19 crisis. 1940 IMPERIAL JAPANESE NAVY HEADQUARTERS  TOKYO

QUESTIONS RAISED RE USINDOPACOM READINESS FOR COMBAT: 3/4: Vectors: Heroes, Villains, and Heartbreak on the Bridge of the U.S. Navy Hardcover – April 4, 2023 by  Thomas B. Modly  (Author) https://www.amazon.com/Vectors-Heroes-Villains-Heartbreak-Bridge/dp/1642257036 Thomas Modly had an eclectic career in the military, academia, business, and government when he answered the call to service in 2017 and returned to the Navy where his career began. His experience, as chronicled in these pages, tells the story of Secretary Modly's quest to advance the Department of the Navy's preparedness for the challenges of this century. As Acting Secretary of the Navy he held fast to the mantra of “acting, not pretending,” and thus advocated aggressively for the Navy and Marine Corps' future ― a future he believed would be defined by uncertainty and unpredictability. Every Friday he wrote a personal message to the entire Department regardless of rank. Those messages were called SECNAV Vectors. Each Vector was intended to clearly communicate his priorities and to establish a rapport with all levels of the organization. The subject of each Vector was inspired by real events that occurred in real time. As these events unfolded , the Secretary's unyielding emphasis on being prepared for unpredictable events are proven to be prescient as the Navy found itself, unintentionally, in the center of COVID-19 crisis. 1905 USN RECEPTION AT TR WHITE HOUSE: DEWEY LEADS

QUESTIONS RAISED RE USINDOPACOM READINESS FOR COMBAT: 4/4: Vectors: Heroes, Villains, and Heartbreak on the Bridge of the U.S. Navy Hardcover – April 4, 2023 by  Thomas B. Modly  (Author) https://www.amazon.com/Vectors-Heroes-Villains-Heartbreak-Bridge/dp/1642257036 Thomas Modly had an eclectic career in the military, academia, business, and government when he answered the call to service in 2017 and returned to the Navy where his career began. His experience, as chronicled in these pages, tells the story of Secretary Modly's quest to advance the Department of the Navy's preparedness for the challenges of this century. As Acting Secretary of the Navy he held fast to the mantra of “acting, not pretending,” and thus advocated aggressively for the Navy and Marine Corps' future ― a future he believed would be defined by uncertainty and unpredictability. Every Friday he wrote a personal message to the entire Department regardless of rank. Those messages were called SECNAV Vectors. Each Vector was intended to clearly communicate his priorities and to establish a rapport with all levels of the organization. The subject of each Vector was inspired by real events that occurred in real time. As these events unfolded , the Secretary's unyielding emphasis on being prepared for unpredictable events are proven to be prescient as the Navy found itself, unintentionally, in the center of COVID-19 crisis. 1923 USS IOWA

In this week's episode we'll discuss the outcomes of younger patients with mantle cell lymphoma experiencing late relapse; learn more about mass spectrometry-based assessment of M-protein in peripheral blood during maintenance therapy in multiple myeloma and discuss in vivo CAR T-cell generation in non-human primates using lentiviral vectors.Featured Articles: Outcomes of younger patients with mantle cell lymphoma experiencing late relapse (>24 months): the LATE-POD studyMass spectrometry–based assessment of M protein in peripheral blood during maintenance therapy inmultiple myelomaIn vivo CAR T-cell generation in nonhuman primates using lentiviral vectors displaying a multidomain fusion ligand

Monterey Car Week can be overwhelming.  Join Greg Stanley and find out the 18 cars you must see while in California.  Greg shares them all from the unveilings at The Quail, to the cars on offer at the auctions and on the show field at the Pebble Beach Concours d'Elegance.  Cars mentioned this episode:       RM Sotheby's Best of Show Candidate       RM Sotheby's Big Ferraris on offer       RM Sotheby's Vectors on offer       Koenigsegg 2005 CCR and GT1 Competition Coupe       1975 Porsche 911       Cadillac Sollei       Eccentrica Diablo Restomod       Lamborghini Temerario       Pagani Utopia Roadster       McLaren P18       Porsche Hypercar       1969 Ford GT40 Lightweight       1959 Porsche 718 RSK Center Seat       1919 American LaFrance La Bestioni Torpedo Roadster       1983 Mercedes-Benz 500 SL 'AMG'       1938 Alfa Romeo 8C 2900B Lungo Spider      1913 Mercer 35-J Raceabout Please support our sponsors: RM Sotheby's, LLCTLC and Euro Classix. For discounted registration fees for your collector car, RV, boat or other awesome ride, please visit LLCTLC at https://www.llctlc.com/classic Follow The Collector Car Podcast: Website, Instagram, Facebook, YouTube or communicate with Greg directly via Email. Join RM Sotheby's Car Specialist Greg Stanley as he applies over 25 years of insight and analytical experience to the collector car market. Greg interviews the experts, reviews market trends and even has some fun. Podcasts are posted every Thursday and available on Apple Podcast, GooglePlay, Spotify and wherever podcasts are found. See more at www.TheCollectorCarPodcast.com or contact Greg directly at Greg@TheCollectorCarPodcast.com. Are you looking to consign at one of RM Sotheby's auctions? Email Greg at GStanley@RMSothebys.com.

Episode 344 Show Notes   Topic of the show: The Benefits of Simulation in Aviation On this week's show, AG and RH discuss how simulators played a part in both the flying side of the mic and the air traffic side of the operation.  For general aviation and aspiring controllers, there is a world of online simulation that can provide a practical and realistic training environment.  We also discuss vectors to final, coordination for departures off airports near a boundary, and more of your awesome aviation questions and feedback.  This is a fun episode and you don't want to miss it!    Links: TOP DOWN https://www.youtube.com/live/_haoRw-ZfNI Training Syllabus here  EVENT FOOTAGE https://www.youtube.com/live/ordoEySqahw Global Site: https://vatsim.net USA Site: https://www.vatusa.net     Timely Feedback: 1. Patron WTF talks about runway renumbering 2. Patron ACF decorates dead trees with useful aviation info 3. Patron BG solos at 16 and has a story   Feedback 1. Patron DGL sent audio feedback about the Triangle of Conflict and an AG imitation 2. Patron WTF asks about boundary airport ops 3. Patron DF has a tip on GPS use and vectors to final   Have a great week and thanks for listening!  Visit our website at OpposingBases.com You can support our show using Patreon or visiting our support page on the website.  Keep the feedback coming, it drives the show! Don't be shy, use the “Send Audio to AG and RH” button on the website and record an audio message. Or you can send us comments or questions to feedback@opposingbases.com.  Music bumpers by audionautix.com.  Third party audio provided by liveatc.net.  Legal Notice The views and opinions expressed on Opposing Bases Air Traffic Talk are for entertainment purposes only and do not represent the views, opinions, or official positions of the FAA, Penguin Airlines, or the United States Army.  Episodes shall not be recorded or transcribed without express written consent. For official guidance on laws, rules, and regulations, consult an aviation attorney or certified flight instructor. 

Ticks & Lyme Disease is the topic of the week!  Our guest is Dr. Myriah Hinchey, a Naturopathic physician and Fellow of the Medical Academy of Pediatric Special Needs (MAPS), is a recognized expert in the field of Lyme disease and other complex chronic inflammatory conditions, with over 17 years of specialized experience. As a physician and the Medical Director at TAO, an integrative center for healing, she has successfully guided thousands of patients towards recovery from their complex chronic inflammatory conditions. Additionally, she is the founder and owner of LymeCore Botanicals, a herbal medicine company focused on providing effective solutions for healing vector-borne diseases. Dr. Hinchey is dedicated to treating patients of all ages, with a specialty in pediatrics, and is also a sought-after speaker, passionately educating healthcare professionals on the pathophysiology of vector-borne diseases and how to successfully integrate functional, herbal, and lifestyle medicine into their practices. 

Speaker Resources:Ashleigh's YT Channel: https://www.youtube.com/@AshleighFaithTools of the Month:Abk: Any Airline using Windows 3.1

Welcome to The Nonlinear Library, where we use Text-to-Speech software to convert the best writing from the Rationalist and EA communities into audio. This is: I found >800 orthogonal "write code" steering vectors, published by Jacob G-W on July 16, 2024 on LessWrong. Produced as part of the MATS Summer 2024 program, under the mentorship of Alex Turner (TurnTrout). A few weeks ago, I stumbled across a very weird fact: it is possible to find multiple steering vectors in a language model that activate very similar behaviors while all being orthogonal. This was pretty surprising to me and to some people that I talked to, so I decided to write a post about it. I don't currently have the bandwidth to investigate this much more, so I'm just putting this post and the code up. I'll first discuss how I found these orthogonal steering vectors, then share some results. Finally, I'll discuss some possible explanations for what is happening. Methodology My work here builds upon Mechanistically Eliciting Latent Behaviors in Language Models (MELBO). I use MELBO to find steering vectors. Once I have a MELBO vector, I then use my algorithm to generate vectors orthogonal to it that do similar things. Define f(x)as the activation-activation map that takes as input layer 8 activations of the language model and returns layer 16 activations after being passed through layers 9-16 (these are of shape n_sequence d_model). MELBO can be stated as finding a vector θ with a constant norm such that f(x+θ) is maximized, for some definition of maximized. Then one can repeat the process with the added constraint that the new vector is orthogonal to all the previous vectors so that the process finds semantically different vectors. Mack and Turner's interesting finding was that this process finds interesting and interpretable vectors. I modify the process slightly by instead finding orthogonal vectors that produce similar layer 16 outputs. The algorithm (I call it MELBO-ortho) looks like this: 1. Let θ0 be an interpretable steering vector that MELBO found that gets added to layer 8. 2. Define z(θ) as 1SSi=1f(x+θ)i with x being activations on some prompt (for example "How to make a bomb?"). S is the number of tokens in the residual stream. z(θ0) is just the residual stream at layer 16 meaned over the sequence dimension when steering with θ0. 3. Introduce a new learnable steering vector called θ. 4. For n steps, calculate z(θ)z(θ0) and then use gradient descent to minimize it (θ is the only learnable parameter). After each step, project θ onto the subspace that is orthogonal to θ0 and all θi. Then repeat the process multiple times, appending the generated vector to the vectors that the new vector must be orthogonal to. This algorithm imposes a hard constraint that θ is orthogonal to all previous steering vectors while optimizing θ to induce the same activations that θ0 induced on input x. And it turns out that this algorithm works and we can find steering vectors that are orthogonal (and have ~0 cosine similarity) while having very similar effects. Results I tried this method on four MELBO vectors: a vector that made the model respond in python code, a vector that made the model respond as if it was an alien species, a vector that made the model output a math/physics/cs problem, and a vector that jailbroke the model (got it to do things it would normally refuse). I ran all experiments on Qwen1.5-1.8B-Chat, but I suspect this method would generalize to other models. Qwen1.5-1.8B-Chat has a 2048 dimensional residual stream, so there can be a maximum of 2048 orthogonal vectors generated. My method generated 1558 orthogonal coding vectors, and then the remaining vectors started going to zero. I'll focus first on the code vector and then talk about the other vectors. My philosophy when investigating language model outputs is to look at the outputs really hard, so I'll give a bunch of examples of outputs. Feel free to skim them. You can see the full outputs of all t...

We brought on Josh from The Worst of All Possible Worlds podcast to talk about an apocalyptic conspiracy theory that is gaining traction in evangelical online spaces: the red heifer sacrifices. But we also had to also bring back Marcos to examine this information through the vaguely schizophrenic lens of his new worldview: the chiral vectors. We recommend smoking weed out of a can to get aluminum poisoning for this episode. Also possibly ingesting some ayahuasca. Find Josh at twitter.com/boshj  Find Marcos at twitter.com/aintershow

The largest slave uprising in the 18th century British Caribbean was also a node of the global conflict called the Seven Year's War, though it isn't usually thought of that way. In the first few days of the quarantine and our current geopolitical and epidemiological shitshow, John and Elizabeth spoke with Vincent Brown, who recently published Tacky's Revolt: The Story of an Atlantic Slave War (Harvard UP, 2019), centered on a group of enslaved West Africans, known under the term “Coromantees” who were the chief protagonists in this war. Tracing the vectors of this war within the Caribbean, the North Atlantic, and West Africa, Vince shows us how these particular enslaved Africans, who are caught in the gears of one of human history's most dehumanizing institutions, constrained by repressive institutions, social-inscribed categories of differences and brutal force, operate tactically within and across space in complex and cosmopolitan ways. Vince locates his interest in warfare (as an object of study) in emergence of new world order and disorder through the Gulf Wars. His attention to routes and mobilities he credits to an epidemiological turn of mind–perhaps inherited from his father Willie Brown, a medical microbiologist now retired from UCSD. The idea of the vector shaped his first book as well. Vince's “cartographic narrative” “A Slave Revolt in Jamaica: 1760-1761” and the film he produced with director Llewellyn Smith, Herskovits at the Heart of Blackness (which traces African studies and anthropology's understanding of cultural movements from between Africa and the Americas) also explore these burning questions. Along the way, Vince discusses C.L.R. James' notion of conflict, war and global connectedness in The Black Jacobins and the ways that categories of social difference both are constituted by global capital (reminding us of our conversation on caste, class and whiteness with Ajantha Subramanian) and those bumper stickers from the early 1980s in which the Taliban were the good guys. Mentioned in this episode: Rambo III (1988) The Interesting Narrative of the Life of Olaudah Equiano, or Gustavus Vassa, the African, written by himself (1789) Aphra Behn, Oroonoko (1688) Catherine Hall, Civilising Subjects: Metropole and Colony in the English Imagination, 1830-1867 (2002) C. L. R. James, The Black Jacobins: Toussaint L'Ouverture and the San Domingo Revolution (1938) John Thornton, Africa and Africans in the making of the Atlantic World-1400-1800 (1992) Derrick ‘Black X' Robinson on his advocacy to make Tacky a national hero in Jamaica Black X walks barefoot across Jamaica to make Tacky a national hero  Recallable Books: Marlon James, The Book of Night Women (2009) John Tutino, Making a New World (2011) Angel Palerm, The First Economic World-System (1980) Listen and Read Here: 34 The Caribbean and Vectors of Warfare: Vincent Brown Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/african-american-studies

The largest slave uprising in the 18th century British Caribbean was also a node of the global conflict called the Seven Year's War, though it isn't usually thought of that way. In the first few days of the quarantine and our current geopolitical and epidemiological shitshow, John and Elizabeth spoke with Vincent Brown, who recently published Tacky's Revolt: The Story of an Atlantic Slave War (Harvard UP, 2019), centered on a group of enslaved West Africans, known under the term “Coromantees” who were the chief protagonists in this war. Tracing the vectors of this war within the Caribbean, the North Atlantic, and West Africa, Vince shows us how these particular enslaved Africans, who are caught in the gears of one of human history's most dehumanizing institutions, constrained by repressive institutions, social-inscribed categories of differences and brutal force, operate tactically within and across space in complex and cosmopolitan ways. Vince locates his interest in warfare (as an object of study) in emergence of new world order and disorder through the Gulf Wars. His attention to routes and mobilities he credits to an epidemiological turn of mind–perhaps inherited from his father Willie Brown, a medical microbiologist now retired from UCSD. The idea of the vector shaped his first book as well. Vince's “cartographic narrative” “A Slave Revolt in Jamaica: 1760-1761” and the film he produced with director Llewellyn Smith, Herskovits at the Heart of Blackness (which traces African studies and anthropology's understanding of cultural movements from between Africa and the Americas) also explore these burning questions. Along the way, Vince discusses C.L.R. James' notion of conflict, war and global connectedness in The Black Jacobins and the ways that categories of social difference both are constituted by global capital (reminding us of our conversation on caste, class and whiteness with Ajantha Subramanian) and those bumper stickers from the early 1980s in which the Taliban were the good guys. Mentioned in this episode: Rambo III (1988) The Interesting Narrative of the Life of Olaudah Equiano, or Gustavus Vassa, the African, written by himself (1789) Aphra Behn, Oroonoko (1688) Catherine Hall, Civilising Subjects: Metropole and Colony in the English Imagination, 1830-1867 (2002) C. L. R. James, The Black Jacobins: Toussaint L'Ouverture and the San Domingo Revolution (1938) John Thornton, Africa and Africans in the making of the Atlantic World-1400-1800 (1992) Derrick ‘Black X' Robinson on his advocacy to make Tacky a national hero in Jamaica Black X walks barefoot across Jamaica to make Tacky a national hero  Recallable Books: Marlon James, The Book of Night Women (2009) John Tutino, Making a New World (2011) Angel Palerm, The First Economic World-System (1980) Listen and Read Here: 34 The Caribbean and Vectors of Warfare: Vincent Brown Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/new-books-network

The largest slave uprising in the 18th century British Caribbean was also a node of the global conflict called the Seven Year's War, though it isn't usually thought of that way. In the first few days of the quarantine and our current geopolitical and epidemiological shitshow, John and Elizabeth spoke with Vincent Brown, who recently published Tacky's Revolt: The Story of an Atlantic Slave War (Harvard UP, 2019), centered on a group of enslaved West Africans, known under the term “Coromantees” who were the chief protagonists in this war. Tracing the vectors of this war within the Caribbean, the North Atlantic, and West Africa, Vince shows us how these particular enslaved Africans, who are caught in the gears of one of human history's most dehumanizing institutions, constrained by repressive institutions, social-inscribed categories of differences and brutal force, operate tactically within and across space in complex and cosmopolitan ways. Vince locates his interest in warfare (as an object of study) in emergence of new world order and disorder through the Gulf Wars. His attention to routes and mobilities he credits to an epidemiological turn of mind–perhaps inherited from his father Willie Brown, a medical microbiologist now retired from UCSD. The idea of the vector shaped his first book as well. Vince's “cartographic narrative” “A Slave Revolt in Jamaica: 1760-1761” and the film he produced with director Llewellyn Smith, Herskovits at the Heart of Blackness (which traces African studies and anthropology's understanding of cultural movements from between Africa and the Americas) also explore these burning questions. Along the way, Vince discusses C.L.R. James' notion of conflict, war and global connectedness in The Black Jacobins and the ways that categories of social difference both are constituted by global capital (reminding us of our conversation on caste, class and whiteness with Ajantha Subramanian) and those bumper stickers from the early 1980s in which the Taliban were the good guys. Mentioned in this episode: Rambo III (1988) The Interesting Narrative of the Life of Olaudah Equiano, or Gustavus Vassa, the African, written by himself (1789) Aphra Behn, Oroonoko (1688) Catherine Hall, Civilising Subjects: Metropole and Colony in the English Imagination, 1830-1867 (2002) C. L. R. James, The Black Jacobins: Toussaint L'Ouverture and the San Domingo Revolution (1938) John Thornton, Africa and Africans in the making of the Atlantic World-1400-1800 (1992) Derrick ‘Black X' Robinson on his advocacy to make Tacky a national hero in Jamaica Black X walks barefoot across Jamaica to make Tacky a national hero  Recallable Books: Marlon James, The Book of Night Women (2009) John Tutino, Making a New World (2011) Angel Palerm, The First Economic World-System (1980) Listen and Read Here: 34 The Caribbean and Vectors of Warfare: Vincent Brown Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/history

The largest slave uprising in the 18th century British Caribbean was also a node of the global conflict called the Seven Year's War, though it isn't usually thought of that way. In the first few days of the quarantine and our current geopolitical and epidemiological shitshow, John and Elizabeth spoke with Vincent Brown, who recently published Tacky's Revolt: The Story of an Atlantic Slave War (Harvard UP, 2019), centered on a group of enslaved West Africans, known under the term “Coromantees” who were the chief protagonists in this war. Tracing the vectors of this war within the Caribbean, the North Atlantic, and West Africa, Vince shows us how these particular enslaved Africans, who are caught in the gears of one of human history's most dehumanizing institutions, constrained by repressive institutions, social-inscribed categories of differences and brutal force, operate tactically within and across space in complex and cosmopolitan ways. Vince locates his interest in warfare (as an object of study) in emergence of new world order and disorder through the Gulf Wars. His attention to routes and mobilities he credits to an epidemiological turn of mind–perhaps inherited from his father Willie Brown, a medical microbiologist now retired from UCSD. The idea of the vector shaped his first book as well. Vince's “cartographic narrative” “A Slave Revolt in Jamaica: 1760-1761” and the film he produced with director Llewellyn Smith, Herskovits at the Heart of Blackness (which traces African studies and anthropology's understanding of cultural movements from between Africa and the Americas) also explore these burning questions. Along the way, Vince discusses C.L.R. James' notion of conflict, war and global connectedness in The Black Jacobins and the ways that categories of social difference both are constituted by global capital (reminding us of our conversation on caste, class and whiteness with Ajantha Subramanian) and those bumper stickers from the early 1980s in which the Taliban were the good guys. Mentioned in this episode: Rambo III (1988) The Interesting Narrative of the Life of Olaudah Equiano, or Gustavus Vassa, the African, written by himself (1789) Aphra Behn, Oroonoko (1688) Catherine Hall, Civilising Subjects: Metropole and Colony in the English Imagination, 1830-1867 (2002) C. L. R. James, The Black Jacobins: Toussaint L'Ouverture and the San Domingo Revolution (1938) John Thornton, Africa and Africans in the making of the Atlantic World-1400-1800 (1992) Derrick ‘Black X' Robinson on his advocacy to make Tacky a national hero in Jamaica Black X walks barefoot across Jamaica to make Tacky a national hero  Recallable Books: Marlon James, The Book of Night Women (2009) John Tutino, Making a New World (2011) Angel Palerm, The First Economic World-System (1980) Listen and Read Here: 34 The Caribbean and Vectors of Warfare: Vincent Brown Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/latin-american-studies

Array Cast - June 7, 2024 Show NotesThis link will take you to the Show notes on the ArrayCast website: https://www.arraycast.com/episode81-show-notes

The largest slave uprising in the 18th century British Caribbean was also a node of the global conflict called the Seven Year's War, though it isn't usually thought of that way. In the first few days of the quarantine and our current geopolitical and epidemiological shitshow, John and Elizabeth spoke with Vincent Brown, who recently published Tacky's Revolt: The Story of an Atlantic Slave War (Harvard UP, 2019), centered on a group of enslaved West Africans, known under the term “Coromantees” who were the chief protagonists in this war. Tracing the vectors of this war within the Caribbean, the North Atlantic, and West Africa, Vince shows us how these particular enslaved Africans, who are caught in the gears of one of human history's most dehumanizing institutions, constrained by repressive institutions, social-inscribed categories of differences and brutal force, operate tactically within and across space in complex and cosmopolitan ways. Vince locates his interest in warfare (as an object of study) in emergence of new world order and disorder through the Gulf Wars. His attention to routes and mobilities he credits to an epidemiological turn of mind–perhaps inherited from his father Willie Brown, a medical microbiologist now retired from UCSD. The idea of the vector shaped his first book as well. Vince's “cartographic narrative” “A Slave Revolt in Jamaica: 1760-1761” and the film he produced with director Llewellyn Smith, Herskovits at the Heart of Blackness (which traces African studies and anthropology's understanding of cultural movements from between Africa and the Americas) also explore these burning questions. Along the way, Vince discusses C.L.R. James' notion of conflict, war and global connectedness in The Black Jacobins and the ways that categories of social difference both are constituted by global capital (reminding us of our conversation on caste, class and whiteness with Ajantha Subramanian) and those bumper stickers from the early 1980s in which the Taliban were the good guys. Mentioned in this episode: Rambo III (1988) The Interesting Narrative of the Life of Olaudah Equiano, or Gustavus Vassa, the African, written by himself (1789) Aphra Behn, Oroonoko (1688) Catherine Hall, Civilising Subjects: Metropole and Colony in the English Imagination, 1830-1867 (2002) C. L. R. James, The Black Jacobins: Toussaint L'Ouverture and the San Domingo Revolution (1938) John Thornton, Africa and Africans in the making of the Atlantic World-1400-1800 (1992) Derrick ‘Black X' Robinson on his advocacy to make Tacky a national hero in Jamaica Black X walks barefoot across Jamaica to make Tacky a national hero  Recallable Books: Marlon James, The Book of Night Women (2009) John Tutino, Making a New World (2011) Angel Palerm, The First Economic World-System (1980) Listen and Read Here: 34 The Caribbean and Vectors of Warfare: Vincent Brown Learn more about your ad choices. Visit megaphone.fm/adchoices

Episode 331 Show Notes   Topic of the show: Weather RH and AG discuss weather as it relates to ATC. Patron EG sent feedback about a resource she has created for increasing pilot safety! Bravo! https://www.youtube.com/@AeroSafe   Timely Feedback: 1.  Patron AW tells us tales of center superiority and flight data flight plan restoration. 2.  Patron CM from the frozen north sent audio feedback about the frozen norther. 3.  Patron SE sent two feedbacks about expected routing and sea plane bases. 4.  Patron BY talks about expected routing. 5.  Patron PS tells us about the lingo for the float plane fraternity Feedback 1.  THE Charlie Alpha sent feedback about the emerald city controllers and their amazing work. 2.  Patron AC sent a question about opposing and crossing downwinds. 3.  Patron MM sent a photo of a proposed airspace redesign at sunny southern airport. 4.  Patron DB tells us how AG hurt him and some comments about tower's airspace, pointouts and audio sound bites.   Have a great week and thanks for listening! Visit our website at OpposingBases.com You can supportour show using Patreon or visiting our support page on the website. Keep the feedback coming, it drives the show! Don't be shy, use the “Send Audio to AG and RH” button on the website and record an audio message. Or you can send us comments or questions to feedback@opposingbases.com. Music bumpers by audionautix.com. Third party audio provided by liveatc.net.   Legal NoticeThe views and opinions expressed on Opposing Bases Air Traffic Talk are for entertainment purposes only and do not represent the views, opinions, or official positions of the FAA, Penguin Airlines, or the United States Army. Episodes shall not be recorded or transcribed without express written consent. For official guidance on laws, rules, and regulations, consult an aviation attorney or certified flight instructor.

FRONTLINE FACING THE PRC SNEAK ATTACK: 3/4: Vectors: Heroes, Villains, and Heartbreak on the Bridge of the U.S. Navy Hardcover –  Thomas B. Modly  (Author) https://www.amazon.com/Vectors-Heroes-Villains-Heartbreak-Bridge/dp/1642257036 Thomas Modly had an eclectic career in the military, academia, business, and government when he answered the call to service in 2017 and returned to the Navy where his career began. His experience, as chronicled in these pages, tells the story of Secretary Modly's quest to advance the Department of the Navy's preparedness for the challenges of this century. As Acting Secretary of the Navy he held fast to the mantra of “acting, not pretending,” and thus advocated aggressively for the Navy and Marine Corps' future ― a future he believed would be defined by uncertainty and unpredictability. Every Friday he wrote a personal message to the entire Department regardless of rank. Those messages were called SECNAV Vectors. Each Vector was intended to clearly communicate his priorities and to establish a rapport with all levels of the organization. The subject of each Vector was inspired by real events that occurred in real time. As these events unfolded , the Secretary's unyielding emphasis on being prepared for unpredictable events are proven to be prescient as the Navy found itself, unintentionally, in the center of COVID-19 crisis. 1904 RUSSO-JAPANESE WAR

FRONTLINE FACING THE PRC SNEAK ATTACK: 4/4: Vectors: Heroes, Villains, and Heartbreak on the Bridge of the U.S. Navy Hardcover –  Thomas B. Modly  (Author) https://www.amazon.com/Vectors-Heroes-Villains-Heartbreak-Bridge/dp/1642257036 Thomas Modly had an eclectic career in the military, academia, business, and government when he answered the call to service in 2017 and returned to the Navy where his career began. His experience, as chronicled in these pages, tells the story of Secretary Modly's quest to advance the Department of the Navy's preparedness for the challenges of this century. As Acting Secretary of the Navy he held fast to the mantra of “acting, not pretending,” and thus advocated aggressively for the Navy and Marine Corps' future ― a future he believed would be defined by uncertainty and unpredictability. Every Friday he wrote a personal message to the entire Department regardless of rank. Those messages were called SECNAV Vectors. Each Vector was intended to clearly communicate his priorities and to establish a rapport with all levels of the organization. The subject of each Vector was inspired by real events that occurred in real time. As these events unfolded , the Secretary's unyielding emphasis on being prepared for unpredictable events are proven to be prescient as the Navy found itself, unintentionally, in the center of COVID-19 crisis. 1905 KORNILOV

FRONTLINE FACING THE PRC SNEAK ATTACK: 2/4: Vectors: Heroes, Villains, and Heartbreak on the Bridge of the U.S. Navy Hardcover –  Thomas B. Modly  (Author) https://www.amazon.com/Vectors-Heroes-Villains-Heartbreak-Bridge/dp/1642257036 Thomas Modly had an eclectic career in the military, academia, business, and government when he answered the call to service in 2017 and returned to the Navy where his career began. His experience, as chronicled in these pages, tells the story of Secretary Modly's quest to advance the Department of the Navy's preparedness for the challenges of this century. As Acting Secretary of the Navy he held fast to the mantra of “acting, not pretending,” and thus advocated aggressively for the Navy and Marine Corps' future ― a future he believed would be defined by uncertainty and unpredictability. Every Friday he wrote a personal message to the entire Department regardless of rank. Those messages were called SECNAV Vectors. Each Vector was intended to clearly communicate his priorities and to establish a rapport with all levels of the organization. The subject of each Vector was inspired by real events that occurred in real time. As these events unfolded , the Secretary's unyielding emphasis on being prepared for unpredictable events are proven to be prescient as the Navy found itself, unintentionally, in the center of COVID-19 crisis. 1904 RUSSO JAPANESE WAR

FRONTLINE FACING THE PRC SNEAK ATTACK: 1/4: Vectors: Heroes, Villains, and Heartbreak on the Bridge of the U.S. Navy Hardcover –  Thomas B. Modly  (Author) https://www.amazon.com/Vectors-Heroes-Villains-Heartbreak-Bridge/dp/1642257036 Thomas Modly had an eclectic career in the military, academia, business, and government when he answered the call to service in 2017 and returned to the Navy where his career began. His experience, as chronicled in these pages, tells the story of Secretary Modly's quest to advance the Department of the Navy's preparedness for the challenges of this century. As Acting Secretary of the Navy he held fast to the mantra of “acting, not pretending,” and thus advocated aggressively for the Navy and Marine Corps' future ― a future he believed would be defined by uncertainty and unpredictability. Every Friday he wrote a personal message to the entire Department regardless of rank. Those messages were called SECNAV Vectors. Each Vector was intended to clearly communicate his priorities and to establish a rapport with all levels of the organization. The subject of each Vector was inspired by real events that occurred in real time. As these events unfolded , the Secretary's unyielding emphasis on being prepared for unpredictable events are proven to be prescient as the Navy found itself, unintentionally, in the center of COVID-19 crisis. 1898 DEWEY'S FLAGSHIP OLYMPIA

In this episode, Ian and Dan discuss the concept of doing things that don't scale, inspired by Paul Graham's influential article 'Do Things That Don't Scale.' They explore the idea of taking risks and gambling in entrepreneurship, and how it relates to increasing one's locus of control. The conversation covers various strategies for founders, including recruiting users manually, building something fragile, delighting users, focusing on experience, and niche marketing. In this conversation, Ian and Dan discuss Paul Graham's article 'Do Things That Don't Scale' and explore the principal themes and takeaways. They cover topics such as the idea of scaling, fabricating products yourself, consulting and acting as an anchor client, going manual and doing unscalable laborious tasks, the illusion of big launches and partnerships, vectors vs. scalars (ideas and execution), and the temptation to gamble and the importance of locus of control. Our book: Before the Exit (https://www.amazon.com/Before-Exit-Thought-Experiments-Entrepreneurs/dp/1980628823/ref=sr_1_1?crid=3E5PMCCM0TDZ0&dib=eyJ2IjoiMSJ9.GnIb36rltn6NgcjHBCs8zg.waeKvE3zKoAbCt6Adoo5o5vv7M4PDyOj9pMXE7dM82A&dib_tag=se&keywords=before+the+exit+dan+andrews&qid=1711510466&s=books&sprefix=before+the+exit+dan+andrews%2Cstripbooks%2C101&sr=1-1) The Newsletter (https://tropicalmba.com/subscribe) “The DC” (https://dynamitecircle.com/join-dc/) DC Black (https://dynamitecircle.com/dc-black) Global events (https://dynamitecircle.com/events) Hire remote talent (https://remotefirstrecruiting.com/) Find a remote job (https://dynamitejobs.com/) Listen on YouTube (https://www.youtube.com/@OfficialTropicalMBA) Follow on Instagram (https://www.instagram.com/tropicalmba/) @TropicalMBA (https://twitter.com/TropicalMBA) @AnythingIan (https://twitter.com/AnythingIan) Chapters ● (00:00:47) Introduction and Waking Up Early ● (00:01:58) The Concept of Taking Risks and Gambling ● (00:03:52) Introduction to Paul Graham and Y Combinator ● (00:05:37) The Importance of Doing Things That Don't Scale ● (00:10:00) Recruiting Users Manually ● (00:12:48) Building Something Fragile ● (00:20:48) Niche Marketing ● (00:23:02) The Facebook and the Idea of Scaling ● (00:24:53) Consulting and Acting as an Anchor Client ● (00:27:17) Going Manual and Doing Unscalable Laborious Tasks ● (00:30:08) The Illusion of Big Launches and Partnerships ● (00:34:54) Vectors vs. Scalars: Ideas and Execution ● (00:38:36) The Temptation to Gamble and the Importance of Locus of Control Links: - Paul Graham's Article “Do Things That Don't Scale” (https://paulgraham.com/ds.html) - Lao Tzu - Philosophy (https://plato.stanford.edu/entries/laozi/) Past guests on TMBA include Cal Newport, David Heinemeier Hannson, Seth Godin, Ricardo Semler, Noah Kagan, Rob Walling, Jay Clouse, Einar Vollset, Sam Dogan, Gino Wickam, James Clear, Jodie Cook, Mark Webster, Steph Smith, Taylor Pearson, Tommy Griffith, Justin Tan, Matt Gartland, Travis Jamison, Ayman Al-Abdullah, Tynan, Lucy Bella Simkins, Brian Balfour, Nick Huber, Mike Michalowicz, Greg Crabtree, Jordan Gal Additional episodes you might enjoy: Three Phases to 1 Million in Revenue (https://tropicalmba.squarespace.com/config/) Quiet Crypto, The Demand Question, and Difficult Decisions ft. Jordan Gal (https://tropicalmba.com/episodes/quiet-crypto-difficult-decisions) “3 Million in Revenue is a Death Zone" - Financial Strategy with Greg Crabtree (https://tropicalmba.com/episodes/3-million-death-zone)