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Stacy Conlon was diagnosed at 42 with Stage IIb lobular breast cancer. Stacy is a certified mindfulness meditation facilitator and Reiki energy healer. In this episode, Stacy reads her essay “Snip, Surrender, Shine: A Ritual in Resilience” from Wildfire Magazine's 2024 “Body” issue. Stacy's piece takes us along on an act of intentional ritual when removing her hair before chemo, and giving herself a ceremony container to move through a part of her cancer journey. April and Stacy will discuss making different spaces to honor experiences or create closure in the breast cancer journey, Stacy's perspective on resilience, and tips for creating rituals. They will also talk about Stacy's upcoming book Breast Cancer Made Easier.More about Stacy: https://www.instagram.com/stacy_conlon_/https://stacyconlon.com/Purchase the “Body” issue of Wildfire Magazine: https://www.wildfirecommunity.org/shop/p/digital-body24Buy the Wildfire book Igniting the Fire Within: Stories of Healing, Hope & Humor, Inside Today's Young Breast Cancer Community: https://www.amazon.com/dp/B0BJVJ629F?ref_=pe_3052080_397514860Get the free Wildfire “Hot Flashes” email newsletter: https://www.wildfirecommunity.org/newsletter?rq=newsletterLearn about Wildfire writing workshops: https://www.wildfirecommunity.org/workshopsShop Wildfire merch & more: https://www.wildfirecommunity.org/shop*Free* Get Wildfire and The Burn freebies here: https://www.wildfirecommunity.org/freeMore about Wildfire Magazine: https://www.wildfirecommunity.orghttps://www.instagram.com/wildfire_bc_magazine/https://www.facebook.com/wildfirecommunityInformation on submitting your story for consideration to be published in Wildfire Magazine: https://www.wildfirecommunity.org/submissions
Ripped from the pages of the popular Wildfire Magazine anthology, Igniting the Fire Within, we've curated this special mini podcast for you. Each Friday, hear a new bite-sized episode. Featuring “just the stories” from the book read by the authors. Think of this as your dynamic audiobook version of Igniting the Fire Within. Enjoy! This episode features April Stearns reading Christi's essay “Privilege.” Christi Salcedo. BSN, RN. Diagnosed at 30. IDC, Stage IIb, ER+. Sacramento, CA.Buy the Wildfire book Igniting the Fire Within: Stories of Healing, Hope & Humor, Inside Today's Young Breast Cancer Community: https://www.amazon.com/dp/B0BJVJ629F?ref_=pe_3052080_397514860More about Christi: https://www.instagram.com/christileeoleary/Get the free Wildfire email newsletter: https://www.wildfirecommunity.orgLearn about Wildfire writing workshops: https://www.wildfirecommunity.org/workshopsShop Wildfire merch & more: https://www.wildfirecommunity.org/shopSend your voice recording testimonial to editor@wildfirecommunity.org*Free* Get Wildfire and The Burn freebies here: https://www.wildfirecommunity.org/freeFollow Wildfire Magazine:https://www.instagram.com/wildfire_bc_magazine/https://www.facebook.com/wildfirecommunity
San Francisco resident Laurie Pomeranz returns to the podcast for a second time. She is a psychotherapist and brand advocate at Beautycounter. At 42 she was diagnosed with Stage IIb breast cancer. Twelve years later, the cancer returned when Laurie was 54. She now lives with metastatic breast cancer. In this episode Laurie reads her essay “18% Chance of Light” from the 2023 “MBC: Lessons Learned” issue of Wildfire. Laurie's story is about learning her cancer has returned on the eve of a family trip to Iceland. April and Laurie will talk about what it's been like for Laurie sharing her cancer story with her son Jack, how Laurie's mom's cancer story is not her cancer story, and beginning again with cancer and recentering how she spends her energy. They will also ponder living with pronoia rather than paranoia. More about Laurie:https://www.instagram.com/lauriepommie/Purchase the “MBC: Lessons Learned” issue here: https://www.wildfirecommunity.org/shop/p/travel23Listen to another episode of The Burn featuring Laurie: https://player.captivate.fm/episode/decba87d-81f9-4e58-91b0-5ad50d95a7eaBuy the Wildfire book Igniting the Fire Within: Stories of Healing, Hope & Humor, Inside Today's Young Breast Cancer Community: https://www.amazon.com/dp/B0BJVJ629F?ref_=pe_3052080_397514860Get the free Wildfire “Hot Flashes” email newsletter: https://www.wildfirecommunity.org/newsletter?rq=newsletterLearn about Wildfire writing workshops: https://www.wildfirecommunity.org/workshopsShop Wildfire merch & more: https://www.wildfirecommunity.org/shop*Free* Get Wildfire and The Burn freebies here: https://www.wildfirecommunity.org/freeMore about Wildfire Magazine: https://www.wildfirecommunity.orghttps://www.instagram.com/wildfire_bc_magazine/https://www.facebook.com/wildfirecommunityInformation on submitting your story for consideration to be published in Wildfire Magazine: https://www.wildfirecommunity.org/submission
Ripped from the pages of the popular Wildfire Magazine anthology, Igniting the Fire Within, we've curated this special mini podcast for you. Each Friday, hear a new bite-sized episode. Featuring “just the stories” from the book read by the authors. Think of this as your dynamic audiobook version of Igniting the Fire Within. Enjoy! This episode features Lauren Elise Oxenhandler reading her essay “Puberty in Purgatory at Thirty-One.” Lauren Elise Oxenhandler. Life Coach, Reiki Practitioner and Virtual Programming Director for the Breasties. Diagnosed at 30. Stage IIB, Triple Negative. Chicago, IL.Buy the Wildfire book Igniting the Fire Within: Stories of Healing, Hope & Humor, Inside Today's Young Breast Cancer Community: https://www.amazon.com/dp/B0BJVJ629F?ref_=pe_3052080_397514860More about Lauren: https://www.instagram.com/laureneliseox/Hear Lauren's story followed by a conversation with April Stearns on The Burn: https://player.captivate.fm/episode/2f68419c-85ec-4ce0-8a11-3d9b903f431aGet the free Wildfire email newsletter: https://www.wildfirecommunity.orgLearn about Wildfire writing workshops: https://www.wildfirecommunity.org/workshopsShop Wildfire merch & more: https://www.wildfirecommunity.org/shopSend your voice recording testimonial to editor@wildfirecommunity.org*Free* Get Wildfire and The Burn freebies here: https://www.wildfirecommunity.org/freeFollow Wildfire Magazine:https://www.instagram.com/wildfire_bc_magazine/https://www.facebook.com/wildfirecommunity
This week we are sharing a favorite episode from the archives as we take a break from our regular podcast schedule for the winter holidays. April selected this episode from November 2022 to reshare. Enjoy!Kelley Franks is a school social worker from Ohio. She was diagnosed at 36 with Stage IIb breast cancer, then again at 41 with Stage IV MBC. Kelley has a deep wanderlust, and she loves going on adventures. In this episode Kelley reads her piece “Slideshow” from Wildfire Magazine's 2022 “Body” issue. Kelley writes beautifully about snapshots of her cancer experience that flip through her memory like a slideshow. April and Kelley will talk about how hiking provides mental clarity and perspective, parenting through traumatic lows and lovely highs, and the desire to leave a legacy of parental guidance knowing you have terminal cancer. They will also discuss the recent journey Kelley had of hiking the Appalachian Trail while living with MBC.More about Kelly: https://www.instagram.com/kelleyefranks/Buy the Wildfire book Igniting the Fire Within: Stories of Healing, Hope & Humor, Inside Today's Young Breast Cancer Community: https://www.amazon.com/dp/B0BJVJ629F?ref_=pe_3052080_397514860Get the free Wildfire “Hot Flashes” email newsletter: https://www.wildfirecommunity.org/newsletter?rq=newsletterLearn about Wildfire writing workshops: https://www.wildfirecommunity.org/workshopsShop Wildfire merch & more: https://www.wildfirecommunity.org/shop*Free* Get Wildfire and The Burn freebies here: https://www.wildfirecommunity.org/freeMore about Wildfire Magazine: https://www.wildfirecommunity.orghttps://www.instagram.com/wildfire_bc_magazine/https://www.facebook.com/wildfirecommunityInformation on submitting your story for consideration to be published in Wildfire Magazine: https://www.wildfirecommunity.org/submissions
Ripped from the pages of the popular Wildfire Magazine anthology, Igniting the Fire Within, we've curated this special mini podcast for you. Each Friday, hear a new bite-sized episode. Featuring “just the stories” from the book read by the authors. Think of this as your dynamic audiobook version of Igniting the Fire Within. Enjoy! This episode features April Stearns reading “Love in the Time of Chemotherapy” by Christina Zajicek.In memory of Christina Zajicek. Diagnosed at 28. IDC, Stage IIB. Diagnosed at 30 with Stage IV, ER+, PR+.Buy the Wildfire book Igniting the Fire Within: Stories of Healing, Hope & Humor, Inside Today's Young Breast Cancer Community: https://www.amazon.com/dp/B0BJVJ629F?ref_=pe_3052080_397514860Get the free Wildfire email newsletter: https://www.wildfirecommunity.orgLearn about Wildfire writing workshops: https://www.wildfirecommunity.org/workshopsShop Wildfire merch & more: https://www.wildfirecommunity.org/shopSend your voice recording testimonial to editor@wildfirecommunity.org*Free* Get Wildfire and The Burn freebies here: https://www.wildfirecommunity.org/freeFollow Wildfire Magazine:https://www.instagram.com/wildfire_bc_magazine/https://www.facebook.com/wildfirecommunity
Dr Weber discusses the FDA approval of adjuvant nivolumab for patients with completely resected stage IIB/C melanoma, key efficacy data from the CheckMate76K trial, and potential future directions for PD-1 inhibitor–based combinations in the melanoma treatment paradigm.
In discussion with Dr. Sapna Patel, Associate Professor, Director of the Uveal Melanoma, and Melanoma Fellowship Program Director at the MD Anderson Cancer Center we discuss how to treat Cutaneous Melanoma and important nuances from Community Oncology perspective. - Management of Stage 0/IA melanoma - where management is mainly surgery - Who is the most appropriate candidate for lymph node evaluation - Stage IIB and beyond, discussing choice of observation, radiation or immunotherapy especially given recent promising results - In patients with metastatic disease, how to manage BRAF positive vs. negative patient population
Diana Vega was diagnosed at 29 with a type of breast cancer called Pleomorphic sarcoma, Stage IIb. She is a nurse, photographer, floral designer, writer, dancer, singer, songwriter, traveler, and ultimately she is an explorer of possibilities. In this episode Diana reads her essay “I Call Her Mother” from Wildfire Magazine's 2018 “The Caregivers” issue. Her story is also included in the Wildfire book Igniting the Fire Within: Stories of Healing, Hope & Humor, Inside Today's Young Breast Cancer Community. This is a story about finding a chosen mother figure that steps up to support and give care when cancer comes. April and Diana will talk about what Diana's relationship with her chosen mom looks like today, going from being a nurse to becoming the patient, and quality vs. quantity of living a joyful life. Diana has been a Wildfire cover model two times and will share about learning to love her body through visible advocacy. April and Diana will also discuss the survivor's guilt that comes with long term survivorship and how Diana is channeling that guilt in her life now. More about Diana: https://www.instagram.com/dystopiadiana/Buy the Wildfire book Igniting the Fire Within: Stories of Healing, Hope & Humor, Inside Today's Young Breast Cancer Community: https://www.amazon.com/dp/B0BJVJ629F?ref_=pe_3052080_397514860Check out “The Caregivers” issue here: https://www.wildfirecommunity.org/shop/p/digital-caregiversRead another essay by Diana in the “Money” issue: https://www.wildfirecommunity.org/shop/p/money22Get the free Wildfire “Hot Flashes” email newsletter: https://www.wildfirecommunity.org/newsletter?rq=newsletterLearn about Wildfire writing workshops: https://www.wildfirecommunity.org/workshopsShop Wildfire merch & more: https://www.wildfirecommunity.org/shop*Free* Get Wildfire and The Burn freebies here: https://www.wildfirecommunity.org/freeMore about Wildfire Magazine: https://www.wildfirecommunity.orghttps://www.instagram.com/wildfire_bc_magazine/https://www.facebook.com/wildfirecommunityInformation on submitting your story for consideration to be published in Wildfire Magazine: dhttps://www.wildfirecommunity.org/submissions
Drs Sapna P. Patel and Kim A. Margolin sift through the data from studies presented at recent conferences, including the KEYNOTE-942 and RP1 IGNYTE studies. Relevant disclosures can be found with the episode show notes on Medscape (https://www.medscape.com/viewarticle/989036). The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals. Resources An Efficacy Study of Adjuvant Treatment With the Personalized Cancer Vaccine mRNA-4157 and Pembrolizumab in Participants With High-Risk Melanoma (KEYNOTE-942) https://classic.clinicaltrials.gov/ct2/show/NCT03897881?term=Keynote-942&draw=2&rank=1 A Personalized Cancer Vaccine, mRNA-4157, Combined With Pembrolizumab Versus Pembrolizumab in Patients With Resected High-Risk Melanoma: Efficacy and Safety Results From the Randomized, Open-Label Phase 2 mRNA-4157-P201/Keynote-942 Trial https://www.abstractsonline.com/pp8/#!/10828/presentation/10243 Distant Metastasis-Free Survival Results From the Randomized, Phase 2 mRNA-4157-P201/KEYNOTE-942 Trial https://ascopubs.org/doi/abs/10.1200/JCO.2023.41.17_suppl.LBA9503 Neoadjuvant-Adjuvant or Adjuvant-Only Pembrolizumab in Advanced Melanoma https://pubmed.ncbi.nlm.nih.gov/36856617/ Pembrolizumab Versus Placebo as Adjuvant Therapy in Stage IIB or IIC Melanoma: Final Analysis of Distant Metastasis-Free Survival in the Phase 3 KEYNOTE-716 Study https://ascopubs.org/doi/abs/10.1200/JCO.2023.41.17_suppl.LBA9505 Study of RP1 Monotherapy and RP1 in Combination With Nivolumab (IGNYTE) https://www.clinicaltrials.gov/study/NCT03767348?term=Study%20of%20RP1%20Monotherapy%20and%20RP1%20in%20Combination%20With%20Nivolumab%20(IGNYTE)&rank=1 Talimogene Laherparepvec (T-VEC): An Intralesional Cancer Immunotherapy for Advanced Melanoma https://pubmed.ncbi.nlm.nih.gov/33803762/ Randomized, Double-blind, Placebo-Controlled, Global Phase III Trial of Talimogene Laherparepvec Combined With Pembrolizumab for Advanced Melanoma https://pubmed.ncbi.nlm.nih.gov/35998300/ Phase I Study of Fianlimab, a Human Lymphocyte Activation Gene-3 (LAG-3) Monoclonal Antibody, in Combination With Cemiplimab in Advanced Melanoma https://oncologypro.esmo.org/meeting-resources/esmo-congress/phase-i-study-of-fianlimab-a-human-lymphocyte-activation-gene-3-lag-3-monoclonal-antibody-in-combination-with-cemiplimab-in-advanced-melanoma Significant Durable Response With Fianlimab (Anti-LAG-3) and Cemiplimab (Anti-PD-1) in Advanced Melanoma: Post Adjuvant PD-1 Analysis https://ascopubs.org/doi/abs/10.1200/JCO.2023.41.16_suppl.9501?af=R Relatlimab and Nivolumab Versus Nivolumab in Untreated Advanced Melanoma https://pubmed.ncbi.nlm.nih.gov/34986285/ BRAF and MEK Inhibition in Melanoma https://pubmed.ncbi.nlm.nih.gov/25648338/ Anti-PD-1 and Anti-CTLA-4 Therapies in Cancer: Mechanisms of Action, Efficacy, and Limitations https://pubmed.ncbi.nlm.nih.gov/29644214/ Society for Immunotherapy of Cancer (SITC) Consensus Definitions for Resistance to Combinations of Immune Checkpoint Inhibitors https://pubmed.ncbi.nlm.nih.gov/36918224/ RECIST 1.1 – Update and Clarification: From the RECIST Committee https://pubmed.ncbi.nlm.nih.gov/27189322/ Histopathological Features of Complete Pathological Response Predict Recurrence-Free Survival Following Neoadjuvant Targeted Therapy for Metastatic Melanoma https://pubmed.ncbi.nlm.nih.gov/32739408/
Ripped from the pages of the popular Wildfire Magazine anthology, “Igniting the Fire Within,” we've curated this special mini podcast for you. Each Friday, hear a new bite-sized episode. Featuring “just the stories” from the book read by the authors. Think of this as your dynamic audiobook version of Igniting the Fire Within. Enjoy! This episode features Meaghan Calcari Campbell reading her essay “Dear One.” Meaghan Calcari Campbell. Ocean Conservation Practitioner. Diagnosed at 32. IDC, Stage IIB, Triple Positive. San Francisco, CA. @calcariousBuy the Wildfire book “Igniting the Fire Within: Stories of Healing, Hope & Humor, Inside Today's Young Breast Cancer Community”: https://www.amazon.com/dp/B0BJVJ629F?ref_=pe_3052080_397514860More about Meaghan: https://www.instagram.com/calcarious/Hear Meaghan's story followed by a conversation with April Stearns on The Burn: https://player.captivate.fm/episode/07b5270a-2a22-4a73-9abd-ca75b4ae9a75Get the free Wildfire email newsletter: https://www.wildfirecommunity.orgLearn about Wildfire writing workshops: https://www.wildfirecommunity.org/workshopsShop Wildfire merch & more: https://www.wildfirecommunity.org/shopSend your voice recording testimonial to editor@wildfirecommunity.org*Free* Get Wildfire and The Burn freebies here: https://www.wildfirecommunity.org/free
Ripped from the pages of the popular Wildfire Magazine anthology, “Igniting the Fire Within,” we've curated this special mini podcast for you. Each Friday, hear a new bite-sized episode. Featuring “just the stories” from the book read by the authors. Think of this as your dynamic audiobook version of Igniting the Fire Within. Enjoy! This episode features Laurie Hessen Pomeranz reading her essay “The Day My Nipple Fell Off.” Laurie is a psychotherapist in private practice and Director at Beautycounter. Diagnosed at 42. IDC and ILC, Stage IIB, ER+, PR+. San Francisco, CA. Buy the Wildfire book “Igniting the Fire Within: Stories of Healing, Hope & Humor, Inside Today's Young Breast Cancer Community”: https://www.amazon.com/dp/B0BJVJ629F?ref_=pe_3052080_397514860More about Laurie: https://www.instagram.com/lauriepommie/Hear Laurie's story followed by a conversation with April Stearns on The Burn:https://player.captivate.fm/episode/decba87d-81f9-4e58-91b0-5ad50d95a7eaGet the free Wildfire email newsletter: https://www.wildfirecommunity.orgLearn about Wildfire writing workshops: https://www.wildfirecommunity.org/workshopsShop Wildfire merch & more: https://www.wildfirecommunity.org/shopSend your voice recording testimonial to editor@wildfirecommunity.org*Free* Get Wildfire and The Burn freebies here: https://www.wildfirecommunity.org/free
CME credits: 0.25 Valid until: 09-06-2024 Claim your CME credit at https://reachmd.com/programs/cme/preventing-disease-recurrence-adjuvant-therapy-stage-iibiic-melanoma/15392/ The 5-year recurrence rates for stage IIB and IIC melanoma are up to 46%, but now new immunotherapy options are FDA-approved for the adjuvant treatment of stage IIB and IIC melanoma. Find out why this matters and hear Drs. Jason Luke and Tara Mitchell break down the latest data on treating stage IIB and IIC melanoma with adjuvant immunotherapy.=
Host: Jason J. Luke, MD, FACP Guest: Tara Mitchell, MD The 5-year recurrence rates for stage IIB and IIC melanoma are up to 46%, but now new immunotherapy options are FDA-approved for the adjuvant treatment of stage IIB and IIC melanoma. Find out why this matters and hear Drs. Jason Luke and Tara Mitchell break down the latest data on treating stage IIB and IIC melanoma with adjuvant immunotherapy.
Ripped from the pages of the popular Wildfire Magazine anthology, “Igniting the Fire Within,” we've curated this special mini podcast for you. Each Friday, hear a new bite-sized episode. Featuring “just the stories” from the book read by the authors. Think of this as your dynamic audiobook version of Igniting the Fire Within. Enjoy! This episode features Denise Archer reading her essay “Dynamite for the Dinner Table.” Denise is a sewist, writer, and part-time school bus driver. Diagnosed at 45. IDC, Stage IIB, Triple Negative. Portland, OR. This episode contains explicit language.Buy the Wildfire book “Igniting the Fire Within: Stories of Healing, Hope & Humor, Inside Today's Young Breast Cancer Community”: https://www.amazon.com/dp/B0BJVJ629F?ref_=pe_3052080_397514860More about Denise: https://www.instagram.com/h.o.m.u.n.c.u.l.u.s/Hear Denise's stories followed by a conversation with April Stearns on The Burn: https://player.captivate.fm/episode/77ec508a-de6d-47cd-ac05-858e1ea34525https://player.captivate.fm/episode/18c7e32b-7574-42ed-a7ea-804710a39abfGet the free Wildfire email newsletter: https://www.wildfirecommunity.orgLearn about Wildfire writing workshops: https://www.wildfirecommunity.org/workshopsShop Wildfire merch & more: https://www.wildfirecommunity.org/shopSend your voice recording testimonial to editor@wildfirecommunity.org*Free* *Free* Get Wildfire and The Burn freebies here: https://www.wildfirecommunity.org/free
Canadian Kim Angell is a human resources consultant and patient advocate. Kim was initially diagnosed with Stage IIb, hormone positive lobular breast cancer at 34. At 38, her cancer returned. Kim is now living with Stage IV metastatic triple negative breast cancer. Kim has a passion for advocacy work and has contributed to various breast cancer campaigns over the years. In this episode, Kim reads her essay “Inviting Conversations About Death” from Wildfire Magazine's 2022 “Legacy Stories” issue. It is a thoughtful piece about facing mortality and having hard conversations about death. April and Kim will discuss the need to talk about death to accommodate logistics, relieving fear and expressing wants. They'll touch on finding joyful times while living with terminal breast cancer, the curiosity surrounding death, and the importance of modeling and normalizing talking about mortality. Kim will also share what writing means to her when it comes to expressing and processing her thoughts to communicate with others. More about Kim: https://www.instagram.com/kangell82/https://www.facebook.com/profile.php?id=100042887298776https://smilethroughthefog.wordpress.com/?fbclid=IwAR0if1plpYJ7S-171fIef6I3_XsrltHSKwD5YSsoDBsTEg5yIYGBfZ57ZFI/More about this episode's sponsor, Bright Spot Network: https://www.brightspotnetwork.org/Purchase a copy of the “Legacy Stories” issue: https://www.wildfirecommunity.org/shop/digital-download-identity20Buy the Wildfire book “Igniting the Fire Within: Stories of Healing, Hope & Humor, Inside Today's Young Breast Cancer Community”: https://www.amazon.com/dp/B0BJVJ629F?ref_=pe_3052080_397514860More about Wildfire: https://www.wildfirecommunity.org.Get the free Wildfire email newsletter: https://www.wildfirecommunity.orgLearn about Wildfire writing workshops: https://www.wildfirecommunity.org/workshopsShop Wildfire merch & more: https://www.wildfirecommunity.org/shop*Free* The Burn Writing Companion: Guided Prompt Journal (Vol. 1): https://www.wildfirecommunity.org/the-burn
Kelley Franks is a school social worker from Ohio. She was diagnosed at 36 with Stage IIb breast cancer, then again at 41 with Stage IV MBC. Kelley has a deep wanderlust and loves going on adventures. In this episode Kelley reads her piece “Slideshow” from Wildfire Magazine's 2022 “Body” issue. Kelley writes beautifully about snapshots of her cancer experience that flip through her memory like a slideshow. April and Kelley will talk about how hiking provides mental clarity and perspective, parenting through traumatic lows and lovely highs, and the desire to leave a legacy of parental guidance knowing you have terminal cancer. They will also discuss the recent journey Kelley had of hiking the Appalachian Trail while living with MBC.More about Kelley: https://www.instagram.com/kelleyefranks/Get the free Wildfire email newsletter: https://www.wildfirecommunity.orgLearn about Wildfire writing workshops: https://www.wildfirecommunity.org/workshopsShop Wildfire merch & more: https://www.wildfirecommunity.org/shopSend your voice recording testimonial to editor@wildfirecommunity.org*Free* The Burn Writing Companion: Guided Prompt Journal (Vol. 1): https://www.wildfirecommunity.org/the-burnBuy the Wildfire book “Igniting the Fire Within: Stories of Healing, Hope & Humor, Inside Today's Young Breast Cancer Community”: https://www.amazon.com/dp/B0BJVJ629F?ref_=pe_3052080_397514860
Featuring perspectives from Dr Lecia Sequist, including the following topics: Introduction: Journal Club with Lecia V Sequist, MD, MPH (0:00) Case: A woman in her early 70s with Stage IIB adenocarcinoma of the lung and an EGFR exon 19 mutation— Adam R Miller, MD (19:26) Case: A man in his late 70s with metastatic adenocarcinoma of the lung and an EGFR L858R mutation develops hemoptysis from an “escape lesion” on osimertinib — Priya Rudolph, MD, PhD (24:59) Case: A man in his early 70s with metastatic adenocarcinoma of the lung (PD-L1 high) and an EGFR L858R mutation experiences disease progression on pembrolizumab — Sandip Patel, MD (28:45) Case: A woman in her mid 60s with metastatic adenocarcinoma of the lung with an EGFR exon 20 insertion with multiple brain and bone metastases (PD-L1
Lung cancer is one of the most commonly diagnosed type of cancer and so it is fitting that we start the first of our disease-specific oncology series with this diagnosis. This week, we round out our discussion of early stage lung cancer treatment!* When deciding if a patient can get surgery upfront or not, remember the three “Fellow on Call” criteria for early stage lung cancer: - Mass invading other structures or mediastinum- Central lymph nodes (single digit)- Tumor >7 cm* If surgery is NOT an option at this time, where do we go from here?- Treat with upfront concurrent definitive chemoradiation- Treat with “induction” chemotherapy or induction concurrent chemoradiation**If surgery is/may be possible***What are the goals of “induction” treatments? - Eradicate microscopic disease- Improved local control, possibly shrinkage- Adding radiation may allow you to downstage tumor or lymph nodes to have a possible improvement in surgical outcomes* What sorts of discussions are being had a thoracic tumor board in patients with newly diagnosed early stage NSCLC? - Is the patient a surgical candidate?- If the patient is not a surgical candidate, then what are the options:--Definitive concurrent chemoradiation (usually) followed by immunotherapy---Pearl 1: Always choose this if surgeon thinks the patient is unresectable in general even with an induction approach---Pearl 2: Always choose this if 2 out of 3 criteria we discussed above are met---Pearl 3: Always choose this if N3 disease- “Induction” regimen with either chemotherapy alone or concurrent chemoradiation followed by surgery * What's the idea behind “induction” chemo or chemoradiation? - There is a chance that patients with these high risk features may already have micrometastatic disease, so treatment upfront can help address that- There is a chance that after surgery, patient may suffer deconditioning, which may preclude the use of chemo +/- radiation (up to 90% of patients are often eligible for chemoradiation before surgery; this drops to ~60% after surgery)- Local disease control to achieve the best possible surgical outcome (R0 resection) and also prevent any microscopic residual disease from then having the opportunity to spread systemically, especially in areas where the mass may be adjacent to many blood vessels or lymph nodes* What to treat with in the neoadjuvant setting?- Platinum containing regimens (“platinum doublets”):-- Carboplatin + paclitaxel-- Cisplatin + etoposide-- Cisplatin + gemcitable-- Cistplain + pemetrexed- Can combine this with radiation* How does the data about chemotherapy+IO in the neoadjuvant setting fit in here (CHECKMATE 816)?- In patients with Stage IIB to IIIA (8th edition) WITHOUT EGFR or ALK mutation, treatment with NEOADJUVANT chemotherapy q3w x3 cycles (most got cisplatin based therapy) + nivolumab 360mg q3w x3 cycles resulted in improved event free survival (31.6 months vs. 20.8 months) AND pathological complete response was 24.0% vs. 2.2%- Current NCCN guidelines state that if nivolumab is used in neoadjuvant setting, it should not be used in adjuvant setting- There is still uncertainty about how this fits into treatment compared to “traditional” neoadjuvant approaches with chemo+/-radiation*So after neoadjuvant treatment, does everyone go to surgery?- Always re-assess the status of the disease; if there is progression of disease, then will go to definitive chemoradiation- Discuss with surgeons to confirm if the patient is still a surgery candidate* If patient undergoes surgery, then what?- If patient got neoadjuvant therapy and an R0, then they are done with treatment- If R0 resection was not able to achieved, then either radiation “boost” to the area (if they previously got radiation), a course of radiation (if they just got induction chemo) or re-resection- We discuss the adjuvant setting in more detail in Episode 026 (https://www.thefellowoncall.com/tfocpodcast/episode-001disclaimer-wfhgf-ml3b6-9m66a-8rrc4-k8w87-x7xdd-wrzye-4xg8x-t73gt-cxc5s-nmg8f-cfyd6-hgs35-5pcwx-tf6dh-trggt-xzkt7-923gg-rpjzx-6s36p-hk27n-bbpgx-jymml-9lfam-76m4s)** If surgery is not possible*** If patient cannot go through to surgery Definitive chemoradiation:- Same chemotherapy agents as above, but treatment course is longer.- For instance, for NSCLC, total 60Gy in 2Gy divided fractions (5 days/week, 6 weeks of treatment) with chemotherapy* Additional therapy after chemoradiation (PACIFIC Trial) - Found that “consolidation” durvalumab 44% PFS 18 months vs 20% 5year survival benefit 40% vs. ~30% without treatmentReferences:https://www.nccn.org/guidelines/guidelines-detail?category=1&id=1450 - NCCN Lung Cancer guidelines https://www.nejm.org/doi/full/10.1056/nejmoa1709937 - PACIFIC Trial (NEJM 2017)https://www.nejm.org/doi/10.1056/NEJMoa2202170 - CHECKMATE 816 (NEJM 2022) Please visit our website (TheFellowOnCall.com) for more information Twitter: @TheFellowOnCallInstagram: @TheFellowOnCallListen in on: Apple Podcast, Spotify, and Google Podcast
Featuring perspectives from Prof Ghassan Abou-Alfa, including the following topics: Introduction (0:00) Case: A woman in her early 50s with metastatic hepatoid carcinoma of the ovary with an FGFR fusion — Syed M Ahmed, MD, PhD (2:56) Key recent data sets (5:59) Case: A man in his mid 60s with a history of Child-Pugh B cirrhosis and Grade 1 esophageal varices who is receiving atezolizumab/bevacizumab for multifocal HCC — Raji Shameem, MD (22:28) Case: A man in his late 60s with previously treated HCC cirrhosis who is now diagnosed with potentially resectable HCC — Syed F Zafar, MD (29:30) Case: A woman in her late 70s receiving adjuvant anastrozole for Stage I breast cancer who is now receiving atezolizumab/bevacizumab for metastatic HCC — Sunil Gandhi, MD (33:41) Case: A man in his late 70s with metastatic HCC and portal vein thrombosis receiving atezolizumab/bevacizumab (NGS [next-generation sequencing] with PIK3CA mutation, PD-L1 50%) — Susmitha Apuri, MD (35:47) Management of Biliary Tract Cancers (40:18) Case: A man in his late 50s with resected Stage IIB gallbladder cancer s/p adjuvant capecitabine who now has metastatic disease (HER2-positive; MSS, PD-L10) — Nasfat Shehadeh, MD (44:01) Case: A woman in her early 40s with a history of ductal carcinoma in situ and family history of breast cancer, now with metastatic cholangiocarcinoma (NGS with IDH2 mutation) — Joanna Metzner-Sadurski, MD (53:41) CME information and select publications
Baddie 2 Baddie Episode 7: When You See Us; My Reconstruction, My Choice” Research shows that Women of Color aren't given many options when it comes to breast reconstruction. These Baddies are dispelling that myth and sharing their decision on the type of reconstruction they chose and why! If you are a breast cancer survivor with questions on which type of breast reconstruction may be right for you, then this episode is a must listen! Hosts: Ginny was diagnosed with ER/PR+ HER2-, stage I, grade 2, Invasive Ductal Carcinoma. After she completed active treatment in early 2020, she found the energy to focus on something other than herself and is now channeling her energy into advocacy and education – allowing herself to find some purpose from her cancer experience. Ginny is using her voice, her body, and her brain to bring attention to disparities in breast cancer diagnosis, treatment, and outcomes between white women and women of color, and to normalize flat closure options after mastectomy. You can reach her at @shudlucky Tandria was diagnosed with stage II IDC/DCIS ER/PR + Her2- breast cancer of the right breast on September 28, 2020, one month after her 30th birthday. She completed chemotherapy, double mastectomy, and radiation, and is now currently on hormone therapy. She's also a flattie! You can follow her at @tangie_e. Natascha Vega is a Group Business Director at an advertising agency in NYC. She loves the creativity that comes with what she does and the opportunity to impact different markets and consumer needs around the globe. Natascha is the proud “fur mom” of an amazing 17-year-old pup who has been her right hand and best companion a gal could ask for. When she isn't deep into her work, you can find her running the streets of Manhattan, logging some miles as she loves to stay active. On September 11, 2020, in the midst of an already chaotic year, Natascha got a call that changed her life forever after detecting a lump the month prior on her right breast: "Ms. Vega, you have triple positive stage 2 breast cancer." Natascha underwent 5 months of chemotherapy, a failed attempt at the cold cap treatment to preserve her hair, 15 rounds of radiation, and lumpectomy surgery. She just finished immunotherapy and is currently taking the proper medications to prevent this from happening again. You can find her on IG @gitana0930. Niya was diagnosed with Stage IIb breast cancer in 2019 while 12 weeks pregnant at the age of 31. Niya's treatment consisted of single mastectomy, four rounds of chemo during pregnancy, four after giving birth, and radiation. Niye began sharing her treatment journey on social media to journal this difficult time in her life. Little did she know that she would connect with many young adults impacted by breast cancer. They would inspire her to advocate for women diagnosed during pregnancy, unilateral mastectomies, breast cancer body image, and financial assistance resources. Niya is a For the Breast of Baddie Ambassador, hosts support groups for parents with cancer in partnership with Smith Center for the Healing and the Arts and Bright Spot Network, and is the board secretary for the Still Standing Alliance. Breast cancer gave Niya a chance to start living the life she always desired. This self-discovery and healing journey helped Niya find herself and discover the magical moments every day. You can find her on IG @niyaspurpose Our Guest: Natalia is a 37 years old with metastatic breast cancer, currently living in a suburb outside of Salt Lake City, UT. She is the mother of a 4 and 6-year-old. She was diagnosed with early-stage breast cancer in 2017 and metastatic breast cancer in 2019. Before breast cancer, Natalia graduated with a Master of Public Administration from ASU and has a passion for public service and activism. Currently, Natalia is a host and senior producer for Our MBC Life podcast. Natalia advocates for breast cancer awareness and education, primarily in the Latinx community and for people of color. Outside of her activism, Natalia enjoys the outdoors, traveling (when possible), cooking, and spending time with her family. You can find her on IG @la_vida_natalia Make sure to follow us on social media: IG: forthebreastofus Twitter: thebreastofus Facebook: For the Breast of Us Private Facebook Group: Breast Cancer Baddies Breastofus.com Baddie Behavior and Baddie 2 Baddie original theme music, podcast production, and mixing by Sincere529 (www.sincere529.com)
This week as we kick back and enjoy the Fourth of July holiday vibes here in the US, we are taking a little break from our regular podcast schedule to re-share with you a favorite episode from the archives. From time to time throughout the year, the Wildfire team will be sharing episodes that really resonate with us personally. Today, Monica Haro has selected this episode about suicidal ideation because she believes can be a mental health aspect of a cancer diagnosis that is not talked about often in the breast cancer community. Jen Rozenbaum is a photographer and author who was diagnosed at 41 with Stage IIb hormone-positive lobular breast cancer. In this episode Jen reads her piece “The Search to Feel Alive” from Wildfire Magazine's 2021 “Grief & Acceptance” issue. Jen tackles the hard subject of suicidal ideation, and the difference between being alive and feeling alive. How do you live your life once you are done with breast cancer treatment and declared No Evidence of Disease when the reality is it is an unrecognizable new life littered with the rubble of your pre-diagnosis existence? What if all you want to do is get in bed and never get out? What if you aren't the badass cancer warrior people think you are? How do you cope when well-meaning outsiders say “at least you are alive” and “you should be celebrating” but you feel minimized and isolated from those comments? The breast cancer community is starting to talk more about mental health, anxiety, and depression - but not so much about suicidal ideation. April will talk more with Jen about survivor's guilt, and the turning points to find help. More about Jen: https://www.instagram.com/jenrozenbaum/ (https://www.instagram.com/jenrozenbaum/) https://jenrozenbaum.com/ (https://jenrozenbaum.com) Jen's podcast: https://open.spotify.com/show/66z9UYVr7oYRMXpNIihhMz (https://open.spotify.com/show/66z9UYVr7oYRMXpNIihhMz) Jen's book: https://www.barnesandnoble.com/w/what-the-f-ck-just-happened-a-survivors-guide-to-life-after-breast-cancer-jen-rozenbaum/1138492714 (https://www.barnesandnoble.com/w/what-the-f-ck-just-happened-a-survivors-guide-to-life-after-breast-cancer-jen-rozenbaum/1138492714) Get the free Wildfire email newsletter: https://www.wildfirecommunity.org/ (https://www.wildfirecommunity.org) Learn about Wildfire writing workshops: https://www.wildfirecommunity.org/workshops (https://www.wildfirecommunity.org/workshops) Shop Wildfire merch & more: https://www.wildfirecommunity.org/shop (https://www.wildfirecommunity.org/shop) Send your voice recording testimonial to editor@wildfirecommunity.org More about this episode's sponsor Bright Spot Network: https://www.brightspotnetwork.org/ (https://www.brightspotnetwork.org/)
Featuring perspectives from Dr Justin Gainor, including the following topics: Introduction (0:00) Immunotherapy for Patients with Targetable Mutations (8:02) Case: A man in his early 80s with recurrent, localized spindle cell carcinoma of the lung, PD-L1 of 40% — Kapisthalam (KS) Kumar, MD (16:03) Case: A woman in her late 50s with microsatellite-stable adenocarcinoma of the lung with an NRG1 fusion — Ranju Gupta, MD (26:57) Case: A woman in her late 50s with metastatic PD-L1-negative adenocarcinoma of the lung and a RET KF5B fusion — Neil Morganstein, MD (32:13) Case: A woman in her early 70s with Stage IIB adenocarcinoma of the lung and an ALK rearrangement, PD-L1 of 5% — Susannah Friemel, MD (37:17) Cases: A woman in her early 50s with metastatic NSCLC and an ALK (2p23) rearrangement, PD-L1 tumor proportion score of 50%; a man in his mid 60s with metastatic adenocarcinoma of the lung involving the brain, an ALK rearrangement and PD-L1 of 20% — Daniel R Carrizosa, MD, MS (41:52) Case: A man in his late 60s with metastatic adenocarcinoma of the lung and a HER2 V659D mutation — Spencer Henick Bachow, MD (47:49) CME information and select publications
Note of warning for sensitive listeners, this episode touches on suicidal ideation. Jen Rozenbaum is a photographer and author who was diagnosed at 41 with Stage IIb hormone-positive lobular breast cancer. In this episode Jen reads her piece “The Search to Feel Alive” from Wildfire Magazine's 2021 “Grief & Acceptance” issue. Jen tackles the hard subject of suicidal ideation, and the difference between being alive and feeling alive. How do you live your life once you are done with breast cancer treatment and declared No Evidence of Disease when the reality is it is an unrecognizable new life littered with the rubble of your pre-diagnosis existence? What if all you want to do is get in bed and never get out? What if you aren't the badass cancer warrior people think you are? How do you cope when well-meaning outsiders say “at least you are alive” and “you should be celebrating” but you feel minimized and isolated from those comments? The breast cancer community is starting to talk more about mental health, anxiety, and depression - but not so much about suicidal ideation. April will talk more with Jen about survivor's guilt, and the turning points to find help. More about Jen: https://www.instagram.com/jenrozenbaum/ (https://www.instagram.com/jenrozenbaum/) https://jenrozenbaum.com/ (https://jenrozenbaum.com) Jen's podcast: https://open.spotify.com/show/66z9UYVr7oYRMXpNIihhMz (https://open.spotify.com/show/66z9UYVr7oYRMXpNIihhMz) Jen's book: https://www.barnesandnoble.com/w/what-the-f-ck-just-happened-a-survivors-guide-to-life-after-breast-cancer-jen-rozenbaum/1138492714 (https://www.barnesandnoble.com/w/what-the-f-ck-just-happened-a-survivors-guide-to-life-after-breast-cancer-jen-rozenbaum/1138492714) Get the free Wildfire email newsletter: https://www.wildfirecommunity.org/ (https://www.wildfirecommunity.org) Learn about Wildfire writing workshops: https://www.wildfirecommunity.org/workshops (https://www.wildfirecommunity.org/workshops) Shop Wildfire merch & more: https://www.wildfirecommunity.org/shop (https://www.wildfirecommunity.org/shop) More about this episode's sponsor Bright Spot Network: https://www.brightspotnetwork.org/ (https://www.brightspotnetwork.org/)
Featuring perspectives from Drs Marc Ladanyi, Andrew McKenzie and Helena Yu, including the following topics: Introduction: Role of Genomic Profiling in Non-Small Cell Lung Cancer (NSCLC) (0:00) Case: A woman in her mid-40s with newly diagnosed Stage IIB adenocarcinoma of the lung and an EGFR L858R mutation — Helena Yu, MD (13:33) Case: A man in his late 70s with metastatic NSCLC and osimertinib resistance due to acquired RET fusion — Marc Ladanyi, MD (23:08) Case: A woman in her mid-60s with newly diagnosed adenocarcinoma of the lung and an EGFR exon 20 mutation — Dr Yu (27:28) Case: A man in his late 70s with Stage IV adenocarcinoma of the lung and a RET fusion — Andrew J McKenzie, PhD (36:49) Case: A man in his late 60s with metastatic mucinous adenocarcinoma of the lung and a HER2 mutation — Spencer Bachow, MD (46:01) Case: A woman in her mid-30s with newly diagnosed metastatic NSCLC and an ALK mutation — Nikesh Jasani, MD (51:57) Case: A man in his late 70s with NSCLC and a TRK fusion — Dr McKenzie (53:24) Case: A woman in her mid-60s with discordant BRAF mutation testing results — Syed Zafar, MD (55:41) CME information and select publications
FDA Drug Information Soundcast in Clinical Oncology (D.I.S.C.O.)
Listen to a soundcast of the December 2 and 3, 2021, FDA approvals of Rituxan (rituximab) plus chemotherapy for pediatric cancer indications, and Keytruda (pembrolizumab) for adjuvant treatment of Stage IIB or IIC melanoma.
Featuring perspectives from Drs Jamie Chaft, Solange Peters, Brendan Stiles and Eric Vallieres, including the following topics: Effect of the recent practice-changing data sets in the adjuvant and neoadjuvant treatment of non-small cell lung carcinoma (NSCLC) (0:00) Case: A woman in her late 60s with Stage IIIA squamous cell carcinoma of the lung and a high level of PD-L1 expression (7:46) Strategies to aid shared decision-making in the adjuvant setting for NSCLC (23:43) Potential role of circulating tumor DNA to detect minimal residual disease in the adjuvant and neoadjuvant settings (28:06) Choosing definitive stereotactic radiosurgery versus sublobar resection in patients with NSCLC (34:53) Case: A woman in her early 80s with PD-L1-negative, Stage IIB lung adenocarcinoma with PIK3CA and TP53 mutations and HER2 amplification (37:24) Experiences with surgery after neoadjuvant systemic therapy in NSCLC (55:38) Case: A woman in her mid-70s with localized pulmonary adenocarcinoma with a MET exon 14 skipping mutation (1:06:23) Clinical outcomes from the Phase III CheckMate 816 trial assessing nivolumab in combination with chemotherapy as neoadjuvant therapy for Stage IB-IIIA NSCLC (1:21:36) Case: A 48-year-old man with a 3.1-cm, Stage IB NSCLC with an EGFR exon 19 deletion (1:35:20) Management of oligometastatic disease with surgery and radiation therapy (1:43:32) Numeracy in adjuvant therapy for NSCLC; estimating the benefit to aid patients in therapeutic decision-making (1:49:11) CME information and select publications
Today's guest is Denise Durgin. Denise is a Patient Experience Performance Advisor at Inova Fairfax Medical Campus in Fairfax Virginia. Before her work in patient experience, Denise worked for 25+ years at Marriott International and The Ritz-Carlton in sales and marketing leadership roles. After leaving Host, Denise became a certified executive coach credentialed with the International Coach Federation. She launched her own executive coaching business and worked one on one with Fortune 100 leaders. Three months after she launched her business, she was unexpectedly diagnosed with Stage IIB breast cancer. After surgery Denise had 28 treatments of proton radiation at The Maryland Proton Treatment Center. She had a hard time getting her insurance to approve her case, when she eventually did, she knew she wanted to give back. She has published a book, Prescription for Proton Radiation that is available on Amazon and Barnes & Noble. In this episode, Denise speaks about how to be a great leader, elevating the patient experience in health care, and her inspiring story of hard work, strength, and resilience.
In this two part series, we're joined by Amin Jaswal who was diagnosed in June 2019 at the age of 29 with Stage IIB glandular adenocarcinoma of the cervix. Nicole and Amin talked about the process of arriving to her diagnosis and how she talked to her family about her cancer. Amin shares her more about the important boundaries and mindset that are important to her as she navigates this journey. Make sure to follow Amin Jaswal on Instagram to follow her on her journey - https://www.instagram.com/aminjaswal/For more information on the Gynecologic Cancer Initiative, please visit https://gynecancerinitiative.ca/ or email us at info@gynecancerinitiative.caWhere to learn more about us:Twitter - https://bit.ly/3jsViHMInstagram - https://bit.ly/3dRQsCFFacebook - https://bit.ly/3knUgOw
Today we speak with Fitz Koehler. She is one of the most prominent and compelling fitness experts and race announcers in America. As the voice of the Los Angeles Marathon, Philadelphia Marathon, Big Sur Marathon, DC Wonder Woman Run Series, and more, she brings big structure, energy, and joy to sport. She's also passionate about guiding others to live better and longer through her company, Fitzness®.Not only do we speak about her experience with Stage IIB breast cancer, but we take a deep dive into the book which is a "tell all" of the juicy and gory details of her 16-month battle, all while zigzagging across the United States. Enduring chemotherapy, radiation, and surgeries in the public eye wasn't easy. You'll laugh, cry, wince, and cheer as she chronicles the clash of an avalanche of side effects with 22 major race weekends. Her inspirational tale encompasses the terror of diagnosis, bald heads and black dresses, spectacular stages, parenting with cancer, perspective, and, most importantly, triumph.Topics discussed in this episode: 05:54: From a clear mammogram to breast cancer 7 weeks later12:00 Blood transfusions, and why you may need it16:20: Noisy Cancer Comeback release and day by day timeline of breast cancer19:08: Starting to loose my long beautiful blond hair24:00: Giving wigs a go32:24: Sneak peaks of what's in the book37:50: Building relationships with your doctors40:00: The pink ribbonResources mentioned in this episode:Fitz Koehler's Website:http://www.fitzness.com/blog/Book: Noisy Cancer Comeback by Fitz Koekler:https://fitzness-store.myshopify.com/Morning Mile:http://www.fitzness.com/blog/the-morning-mile/Madam Glam Pink Collection:https://bit.ly/306ZfezEpisode Quotables: "The doctors said the day before your PET scan, no sugar, no carbs, no caffeine. And then when I got there, they injected me with sugar water, and that is because the sugar goes straight to cancer and makes the cancer dance. "I travel for a living. They all required plane trips. And what my doctors knew was that my career was important to me. It was my passion, and that I needed it. To do my best I needed joy and the things that made me happy.""I didn't earn breast cancer, so it doesn't belong in the first three lines in my bio. I earned my master's degree, I earned the privilege of being spokesperson for Tropicana and Oakley. So those are things I earned. _________________________Say Hi on Social:YouTube: https://www.youtube.com/SURVIVINGBREASTCANCERFacebook:https://www.facebook.com/SurvivingbreastcancerorgPinterest: https://www.pinterest.com/BreastCancerConversations/Twitter: https://twitter.com/SBC_org Instagram: https://www.instagram.com/survivingbreastcancerorg/