Podcasts about localized

Featuring perspectives from Dr Adam M Brufsky and Dr Kevin Kalinsky, including the following topics: Introduction (0:00) Current and Future Role of TROP2-Directed Antibody-Drug Conjugates in Therapy for Triple-Negative Breast Cancer (TNBC) — Dr Brufsky (5:08) Established Treatment Paradigm for Localized and Metastatic TNBC — Dr Kalinsky (35:20) CME information and select publications

Featuring perspectives from Dr Thomas E Hutson, Dr Erik A Singer and Dr Ulka Vaishampayan, moderated by Dr Hutson, including the following topics: Introduction (0:00) Current Indications for Adjuvant Immune Checkpoint Inhibitor Therapy in the Management of Renal Cell Carcinoma (RCC) — Dr Singer (2:32) Potential Role of Hypoxia-Inducible Factor-2 Alpha Inhibitors as a Component of Adjuvant Treatment — Dr Hutson (30:53) Tolerability of Current and Emerging Adjuvant Approaches for RCC — Dr Vaishampayan (1:06:37) CME information and select publications

AUA Guidelines: Clinically Localized Prostate Cancer Host: Mark L. Gonzalgo, MD, PhD, MBA Guest: James Eastham, MD, FACS To access the full guideline, please use the following link: https://www.auanet.org/guidelines-and-quality/guidelines/clinically-localized-prostate-cancer

For this episode of JoJo's Bizarre Adventure, we review Stardust Crusaders: Khnum's Oingo and Thoth's Boingo (E27 of Part 3). If you want peak nonsensical JoJo, this is the episode for you. We discuss Oingo eating cigarettes, Jotaro eating an orange, Boingo's weird laugh, and the bro moments we'll never get to see. Localized episode title: Khnum's Zenyatta and Thoth's Mondatta Join our Discord: https://discord.gg/4Rnq4GTePP Support the podcast: https://www.patreon.com/thestrictlyseries Website: https://www.thestrictlyseries.com Instagram: https://www.instagram.com/thestrictlyseries X (Twitter): https://x.com/strictlyseries Part of The Strictly Series of podcasts

Mary Ellen Taplin joins us on the heels of her ASCO 2026 Plenary presentation with this exciting phase 3 data certain to generate discussion about the landscape of high risk prostate cancer.

As part of the 2026 UCSF Patient Conference on Prostate Cancer, Dr. Julian Hong discusses radiation therapy. Series: "Prostate Cancer Patient Conference" [Health and Medicine] [Show ID: 41551]

As part of the 2026 UCSF Patient Conference on Prostate Cancer, Dr. Julian Hong discusses radiation therapy. Series: "Prostate Cancer Patient Conference" [Health and Medicine] [Show ID: 41551]

As part of the 2026 UCSF Patient Conference on Prostate Cancer, Dr. Julian Hong discusses radiation therapy. Series: "Prostate Cancer Patient Conference" [Health and Medicine] [Show ID: 41551]

Strength training is having a massive moment for women in midlife, but it comes with a silent side effect showing up in clinical offices: pelvic organ prolapse. In this "15-Minute Consult," Dr. Rachel Pope sits down with Dr. Jessica Jenkins, PT, DPT, ATC, to discuss how to protect your pelvic floor while lifting heavy, managing internal abdominal pressure, and keeping your organs exactly where they belong.Key Takeaways: Prolapse Isn't Just for Older Women: Heavy lifting can bring undetected pelvic organ prolapse to light even in young, active women in their 20s who have never given birth. The Danger of Holding Your Breath: Holding your breath or bearing down (Valsalva) during standard strength training acts exactly like straining on the toilet, sending massive downward pressure straight onto your bladder and uterus. The Golden Rule of Lifting: When the movement gets hard, breathe out. On the exertion phase (like pushing up from a squat), exhale, pull in your lower abs, and engage your pelvic floor (Kegel) to push the pressure upward. Listen to Your Body: Experiencing a distinct heaviness or a "tampon is stuck inside" sensation during or after a workout means the weight is too heavy, the pace is too fast, or your mechanics need a reassessment. Underutilized Support Tools: Pessaries (silicone support rings) can be worn strictly as "sports gear" to physically support tissues during workouts. Localized estrogen is also highly effective for restoring tissue extensibility before diving into core rehab. The Power of Hypopressives: This specialized vacuum-breathing technique creates negative pressure in the abdomen, involuntarily lifting the pelvic floor up and in to help train the abdominal wall to support internal organs.Quick Training Tips: Never hold your breath during the exertion or lifting portion of an exercise. Exhale and contract your pelvic floor as you lift to redirect internal pressure safely toward your diaphragm.About Guest Expert Dr. Jessica Jenkins:Dr. Jessica Jenkins is a Doctor of Physical Therapy, Certified Athletic Trainer, and the founder of the Cleveland Pelvic Wellness Center. Driven by her own experience navigating a pelvic floor injury as a competitive cross-country and track athlete, she blends sports medicine principles with specialized pelvic floor rehabilitation to help active individuals master core stability and pressure management.Connect & Resources: Learn More About Dr. Jenkins: Cleveland Pelvic Wellness Center Watch on YouTube: Our Womanity ChannelFree Resources: Get your free copies of: ➡️ The Proactive Perimenopause Guide➡️ "She's Just Under Construction" partner GuideDisclaimer: This podcast is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

//The Wire//2300Z May 25, 2026// //ROUTINE// //BLUF: WEEKEND RHETORIC OF POTENTIAL PEACE DEAL IN MIDDLE EAST GIVES WAY TO RENEWED EFFORTS TO REIGNITE THE WAR IN IRAN. MULTIPLE INDUSTRIAL INCIDENTS REPORTED IN LOS ANGELES. PEPPER SPRAY INCIDENTS CONTINUE IN JAPAN. SHOOTING REPORTED AT WHITE HOUSE.// -----BEGIN TEARLINE------International Events-Japan: This morning a chemical incident was reported at Ginza Six Mall in Tokyo. One individual reportedly sprayed an unidentified noxious substance at one of the entrances to the mall, which resulted in many people becoming ill. 12x individuals reported throat pain, and a total of 25x people sought medical treatment after the substance was released.Analyst Comment: When it comes to chemical incidents involving unknown materials in public places, the potential explanations vary widely. In this case, the origin appears to be pepper spray, with some locals claiming that an argument between two foreign men devolved into one of the two pepper spraying the other. Officially, no statements by authorities have confirmed what happened. As always, incidents like this occurring in Japan are extremely rare as pepper spray is heavily regulated and illegal to carry throughout the country. Consequently, incidents which wouldn't be worth mentioning in the western world result in overwhelming responses in Japan, and in this case this is the second such incident this month. Two weeks ago, someone deployed pepper spray on a train at Kawasaki Station, which occurred without much media attention. -HomeFront-California: Multiple major industrial incidents have taken place in Los Angeles over the past few days. Several days ago, a chemical incident was reported at the GKN Aerospace facility in Garden Grove. The incident involved a cooling system failing inside a large tank holding about 7,000 gallons of methyl methacrylate (UN: 1247), a Toxic Industrial Compound (TIC) used in the manufacture of epoxies and resins. This is a highly unstable compound if not handled appropriately, which can result in chemical reactions taking place inside the tank if certain conditions are met. Over the weekend, these conditions resulted in the evacuation of roughly 50,000 people, with local authorities being concerned that the tank might explode. As of this morning, a crack had formed in the tank, relieving the pressure and reducing the risk of an explosion.Separately, a large fire was reported in South Gate, as an automotive facility burned Sunday afternoon. A shelter-in-place order was issued for the local area due to the smoke and the close proximity of the fire to residential communities. Localized power outages were also reported in the neighborhood, but power was restored after the fire was knocked down throughout the evening.In East Los Angeles, a spill of crude oil was reported after a telecoms crew installing fiber optic lines accidentally hit a petroleum pipeline, causing a rupture. This pipeline break resulted in a few thousand gallons of crude entering the storm drains in the vicinity of the intersection of Caesar Chavez and Eastern Avenue.Washington D.C. - Over the weekend, a small arms engagement was reported at the White House, after a man approached the perimeter fence with a handgun. Authorities state that one individual approached a Secret Service checkpoint and drew a firearm from a bag, before engaging the agents at the checkpoint at the corner of 17th Street and Pennsylvania Avenue. Secret Service personnel engaged the shooter, ending the incident. One bystander was wounded during the incident.Analyst Comment: The suspect has been identified as Nasire Best, who had a long history of presenting security threats to the White House. Best had previously attempted to breach the compound in the past, and had also made verbal threats toward Secret Service personnel. In June of last year, Best was arrested after blocking a traffic lane entering the White House compound, and subsequently committed to a mental institution. -----END TEARLINE-----Analyst Comments: Over the weekend, several developments have taken place with regards to diplomacy in the Middle East. On Saturday, President Trump announced that a peace deal with Iran was "largely negotiated", subject to the final details being worked out. Almost immediately following this announcement, Iranian state media refuted these claims as not being true, or being different from what has been discussed so far during the negotiations. On Sunday, President Trump reversed his stance on the immediacy of the deal being reached, stating that he has instructed his staff to take their time regarding the details of a deal. This morning, the Iranian Foreign Ministry stated that no deal is on the table, and the deadlock continues.As it stands, it's possible that the weekend shenanigans are the result of a few different theories. For one, the rhetoric from the White House could be the standard effort to calm economic markets. Normally, these "good news" social media posts are issued on Monday mornings shortly before the opening bell on Wall Street, but lately have also been taking place late in the week. Conversely, the confusing messaging regarding a potential peace deal could me more organic...it's not the first time that peace talks have collapsed at the eleventh hour all on their own, or from actions by parties around the region objecting to the deal in some manner.It's also possible that this is a repeat of the now long-forgotten final days before this war began, most notably what transpired in the 72 hours leading up to the February 28th attacks. In retrospect, history indicates that even as the last-minute negotiations were taking place, the decision to use military force had been made many days before the war officially began. Likewise, a similar situation might be getting set up right now; it is possible that the US is transitioning into a renewed targeting effort. Until something happens either way, the three main possibilities remain, just as they have since the start of the ceasefire: Either a deal is reached and everything returns to normal as best it can, or the U.S. returns to bombing and the war resumes, or the stalemate continues as before with no real change to any of the points of deadlock. Time will tell what happens next, but for now nothing is signed and the "pause" to the war continues.Analyst: S2A1 Research: https://publish.obsidian.md/s2underground Disclaimer: No LLMs were used in the writing of this report. //END REPORT//

In this Episode: Abey Rae Scaglione has cultivated a deep understanding of the need for animals in our food system, layered upon her decades-long fascination with nutrition and self-sufficiency. After earning her degree in psychology, Abey worked as Pilates instructor in Los Angeles, eventually owning her own studio. Long interested in where our food comes from, it was in Northern California that she fell in love with growing vegetables and raising chickens. In 2021, Abey moved with her husband and two sons to Ruckle Heritage Farm on Salt Spring Island in British Columbia, Canada, where they raise sheep, cattle, turkeys and chickens. As a former vegetarian turned rancher, she has an incredibly intimate relationship with the complex realities of raising animals for food and the deep conviction that more can be done for animal welfare by supporting good farming practices, than by rejecting all animal agriculture.Our Guest: Abey Rae Scaglione has cultivated a deep understanding of the need for animals in our food system, layered upon her decades-long fascination with nutrition and self-sufficiency. After earning her degree in psychology, Abey worked as Pilates instructor in Los Angeles, eventually owning her own studio. Long interested in where our food comes from, it was in Northern California that she fell in love with growing vegetables and raising chickens. In 2021, Abey moved with her husband and two sons to Ruckle Heritage Farm on Salt Spring Island in British Columbia, Canada, where they raise sheep, cattle, turkeys and chickens. As a former vegetarian turned rancher, she has an incredibly intimate relationship with the complex realities of raising animals for food and the deep conviction that more can be done for animal welfare by supporting good farming practices, than by rejecting all animal agriculture.Key TopicsAbey Rae ScaglioneRuckle Heritage FarmRegenerative agricultureLocal food systemsAnimal welfare in agricultureFrom vegetarianism to ranchingSelf-sufficiency and homesteadingRaising sheep, cattle, turkeys, and chickensNutrition and food sourcingSmall-scale farming realitiesSalt Spring Island farming cultureFood resilience and sustainabilityEthical meat productionFamily farmingKey Questions AnsweredWhy did Abey Rae Scaglione transition from vegetarianism to ranching?Abey's evolving understanding of nutrition, ecology, and food systems led her to recognize the important role animals play in regenerative agriculture. Her firsthand experiences growing food and raising animals deepened her perspective on ethical animal stewardship and sustainable farming.How did her background in psychology and wellness shape her approach to farming?Her education in psychology and years as a Pilates instructor gave her insight into health, behavior, and holistic wellness. That foundation naturally expanded into curiosity about food quality, nutrition, and self-reliance.What changed after moving to Salt Spring Island?Relocating to British Columbia in 2021 allowed Abey and her family to fully immerse themselves in farming life at Ruckle Heritage Farm, where they now raise multiple livestock species and participate directly in building resilient local food systems.What does Abey believe about animal welfare?She believes meaningful improvements in animal welfare come from supporting responsible and regenerative farming practices rather than rejecting all forms of animal agriculture.Why are resilient food systems important?Localized and regenerative food systems can strengthen communities, improve soil health, reduce dependence on industrial agriculture, and create more transparency between consumers and producers.Episode HighlightsAbey shares the surprising path from vegetarianism to regenerative ranching.A discussion about why animals are essential to healthy agricultural ecosystems.The realities of raising livestock ethically on a family farm.Insights into reconnecting consumers with where food actually comes from.Reflections on moving from Los Angeles wellness culture to rural farm life.Why supporting small farms can directly improve animal welfare outcomes.The connection between nutrition, ecology, and resilient communities.ResourcesAbey's Website —  radicalfarmbook.comAbey's Book Recommendation - Milk Into Cheese, David AsherVisit www.urbanfarm.org/RadicleFarm for the show notes on this episode, and access to our full podcast library! Need a little bit of advice or just a feedback on your design for your yard or garden?The Urban Farm Team is offering consults over the phone or zoom. Get the benefits of a personalized garden and yard space analysis without the cost of trip charges. You can chat with Greg or choose one of the senior members of our Urban Farm team to get permaculture based feedback.Click HERE to learn more!*Disclosure: Some of the links in our podcast show notes and blog posts are affiliate links and if you go through them to make a purchase, we will earn a nominal commission at no cost to you. We offer links to items recommended by our podcast guests and guest writers as a service to our audience and these items are not selected because of the commission we receive from your purchases. We know the decision is yours, and whether you decide to buy something is completely up to you.

Welcome to another episode of the Oncology Brothers podcast! In this episode, hosts Rahul and Rohit Gosain dive deep into the treatment algorithms for early-stage non-small cell lung cancer (NSCLC) with curative intent. Joined by leading thoracic medical oncologist Dr. Sanjay Popat from London, they discussed the critical role of next-generation sequencing (NGS) in treatment planning, the importance of proper staging, and the implications of actionable mutations. Listen us on: Spotify: https://open.spotify.com/show/31BXhY9FM4gPWG10WgE11o Apple Podcast: https://podcasts.apple.com/us/podcast/oncology-brothers-practice-changing-cancer-discussions/id1653340966 Follow us on social media: X/Twitter: https://twitter.com/oncbrothers ⁠Instagram: https://www.instagram.com/oncbrothers Website: https://oncbrothers.com/ Key topics covered included: The significance of NGS testing and its impact on treatment decisions. Insights from the CHECKMATE 816 trial, highlighting the benefits of neoadjuvant chemoimmunotherapy. The complexities of post-operative immunotherapy and patient-shared decision-making. The role of adjuvant chemotherapy in patients with actionable mutations like EGFR and ALK. The latest data on osimertinib and alectinib in the adjuvant setting. The standard of care for unresectable disease based on the PACIFIC trial and the implications of PD-L1 status. Join us for an informative discussion that unpacks the latest advancements in NSCLC treatment and emphasizes the importance of personalized care. Don't forget to subscribe for more episodes in our treatment algorithm series! #EarlyStageNSCLC, #CHECKMATE816, #NeoadjuvantTherapy, #PrecisionMedicine, #OncologyBrothers

Dr Stacey A Cohen from Fred Hutchinson Cancer Center in Seattle, Washington, Dr Jenny Seligmann from the University of Leeds in the United Kingdom and Dr Christopher Lieu from the University of Colorado Cancer Center in Aurora review clinical findings from the 2026 ASCO Gastrointestinal Cancers Symposium relevant to the management of localized colorectal cancer. CME information and select publications here.

Featuring perspectives from Dr Stacey A Cohen, Dr Christopher Lieu and Dr Jenny Seligmann, moderated by Dr Lieu, including the following topics: Role of circulating tumor DNA (ctDNA) testing in the escalation of treatment for Stage II and deescalation for Stage III colon cancer (0:00) Impact of timing on the clinical relevance of ctDNA minimal residual disease test results in localized colorectal cancer (8:58) Approach to managing Stage III colon cancer with ctDNA-positive results after adjuvant treatment (13:35) CME information and select publications

CME credits: 1.00 Valid until: 01-05-2027 Claim your CME credit at https://reachmd.com/programs/cme/targeting-inflammation-in-ibd-localized-vs-systemic-strategies/56890/ This program provides community gastroenterologists with a foundational overview of IBD, emphasizing how disease biology informs diagnosis, monitoring, and treatment selection. Faculty will cover the multifactorial drivers of disease, including genetic susceptibility, environmental exposures, the gut microbiome, and immune dysregulation. A 3D animation illustrates the pathophysiology of IBD and the immune mechanisms that contribute to chronic intestinal inflammation. Experts also discuss how various therapies interact with these pathways. The program concludes with practical insights on applying a mechanistic understanding of IBD to treatment strategy, disease monitoring, and management decisions in community gastroenterology practice.

Two Onc Docs, hosted by Samantha A. Armstrong, MD, and Karine Tawagi, MD, is a podcast dedicated to providing current and future oncologists and hematologists with the knowledge they need to ace their boards and deliver quality patient care. Dr Armstrong is a hematologist/oncologist and assistant professor of clinical medicine at Indiana University Health in Indianapolis. Dr Tawagi is a hematologist/oncologist and assistant professor of clinical medicine at the University of Illinois in Chicago.In this episode, OncLive On Air® partnered with Two Onc Docs to provide a comprehensive review of localized bladder cancer, covering everything from initial histology to the rapidly evolving treatment paradigms for muscle-invasive disease. Drs Armstrong and Tawagi emphasized that although urothelial carcinoma remains the most common bladder cancer histology, recognizing variants like squamous, adenocarcinoma, and small cell is vital, as they often require surgery-first approaches or specialized chemotherapy. A critical diagnostic pearl highlighted for oncology boards was the necessity of muscularis propria in the transurethral resection of the bladder tumor (TURBT) specimen. If muscle is absent, a repeat TURBT is mandatory to ensure the cancer is not under-staged. For non–muscle-invasive bladder cancer, the treatment goal is preventing recurrence and progression. Patients with high-risk disease should receive BCG induction and maintenance. For those who are BCG unresponsive, Drs Armstrong and Tawagi discussed several novel intravesical therapy options that may be preferred over systemic pembrolizumab to avoid toxicity.The management of muscle-invasive bladder cancer (MIBC) is primarily dictated by cisplatin eligibility, which is determined by performance status, renal function, and the absence of neuropathy or hearing loss. In cisplatin-eligible patients, the phase 3 NIAGARA trial (NCT03732677) results led to a new standard of care (SOC), which is the addition of durvalumab (Imfinzi) to a gemcitabine/cisplatin backbone. Furthermore, the phase 3 KEYNOTE-B15 trial (NCT04700124) data demonstrated that neoadjuvant enfortumab vedotin-ejfv (Padcev) plus pembrolizumab (Keytruda) significantly improved overall survival compared with standard chemotherapy, though this combination is not yet the board-tested standard. For cisplatin-ineligible patients, the phase 3 EV-303 trial (NCT03924895) established neoadjuvant enfortumab vedotin plus pembrolizumab as a new SOC, replacing the previous approach of upfront cystectomy followed by adjuvant nivolumab (Opdivo).Finally, Drs Armstrong and Tawagi discussed trimodal therapy as a bladder-sparing treatment approach. Ideal candidates for this approach must have small tumors, a complete TURBT, no hydronephrosis, and must commit to lifelong cystoscopic surveillance.

Today's episode is focusing on what you need to know regarding localized bladder cancer, with 2026 updates. This will include the need to know pathology, presentation, diagnostic work-up, staging, and treatment options. 

The Internet Report examines the April 2 Microsoft 365 service disruption, an Outlook issue aboard Artemis II, and what these events reveal about critical paths within enterprise architecture. ———  CHAPTERS  00:54 Anatomy of the Microsoft 365 Disruption 02:52 What the Failure Pattern Shows 03:41 Mitigation vs. Resolution 04:58 Outlook Issues on Artemis II: Coincidence? 08:11 Takeaways for NetOps 10:18 Outage Trends: By the Numbers  13:24 Get in Touch   For additional insights, check out The Internet Outage Survival Kit: https://www.thousandeyes.com/resources/the-internet-outage-survival-kit?utm_source=soundcloud&utm_medium=referral&utm_campaign=fy26q3_internetreport_q3fy26ep134_podcast  ———  Want to get in touch?  If you have questions, feedback, or guests you would like to see featured on the show, send us a note at InternetReport@thousandeyes.com or follow us on LinkedIn or X. ———  ABOUT THE INTERNET REPORT  This is The Internet Report, a podcast uncovering what's working and what's breaking on the Internet—and why.   Tune in to hear ThousandEyes' Internet experts dig into some of the most interesting outage events from the past couple weeks, discussing what went awry—was it the Internet, or an application issue?  Plus, learn about the latest trends in ISP outages, cloud network outages, collaboration network outages, and more.  Catch all the episodes on your favorite podcast platform:   - Apple Podcasts: https://podcasts.apple.com/us/podcast/the-internet-report/id1506984526   - Spotify: https://open.spotify.com/show/5ADFvqAtgsbYwk4JiZFqHQ?si=00e9c4b53aff4d08&nd=1&dlsi=eab65c9ea39d4773   - SoundCloud: https://soundcloud.com/ciscopodcastnetwork/sets/the-internet-report   - YouTube: https://www.youtube.com/@theinternetreport_official 

The Internet Report examines the April 2 Microsoft 365 service disruption, an Outlook issue aboard Artemis II, and what these events reveal about critical paths within enterprise architecture. ——— CHAPTERS 00:54 Anatomy of the Microsoft 365 Disruption02:52 What the Failure Pattern Shows03:41 Mitigation vs. Resolution04:58 Outlook Issues on Artemis II: Coincidence?08:11 Takeaways for NetOps10:18 Outage Trends: By the Numbers 13:24 Get in Touch For additional insights, check out The Internet Outage Survival Kit: https://www.thousandeyes.com/resources/the-internet-outage-survival-kit?utm_source=wistia&utm_medium=referral&utm_campaign=fy26q3_internetreport_q3fy26ep134_podcast ——— Want to get in touch? If you have questions, feedback, or guests you would like to see featured on the show, send us a note at InternetReport@thousandeyes.com. Or follow us on LinkedIn or X: @thousandeyes ——— ABOUT THE INTERNET REPORT This is The Internet Report, a podcast uncovering what's working and what's breaking on the Internet—and why. Tune in to hear ThousandEyes' Internet experts dig into some of the most interesting outage events from the past couple weeks, discussing what went awry—was it the Internet, or an application issue? Plus, learn about the latest trends in ISP outages, cloud network outages, collaboration network outages, and more. Catch all the episodes on your favorite podcast platform: - Apple Podcasts: https://podcasts.apple.com/us/podcast/the-internet-report/id1506984526 - Spotify: https://open.spotify.com/show/5ADFvqAtgsbYwk4JiZFqHQ?si=00e9c4b53aff4d08&nd=1&dlsi=eab65c9ea39d4773 - SoundCloud: https://soundcloud.com/ciscopodcastnetwork/sets/the-internet-report - YouTube: https://www.youtube.com/@theinternetreport_official

A quiet Polish family's horse-drawn cart ride home turns into a six-hour nightmare of silent UFOs, phantom fires, screaming triangles, and green humanoids inside a floating cube… and no one else on Earth saw it.On a warm July evening in 1987, in the tiny villages of Bedzienica & Nockowa, Poland, an ordinary family witnessed the impossible. A massive hat-shaped UFO drops from the sky. Their house explodes with blinding white light. Nine glowing spheres hover in perfect formation for hours. A fiery triangle screams overhead. An entire barn bursts into flames… that aren't real. Then two green-suited beings with triangular heads glide toward them in a transparent cube.This is one of the most disturbing and well-documented close encounters from communist-era Poland — yet almost nobody else reported it. Why?In this episode of My Dark Path, I'm MF Thomas, and I'm taking you deep into the Bedzienica-Nockowa Incident — a true story of terror that stayed hidden for 16 years.What really happened that night? Localized phenomenon… military tech… or something not of this world?If you love terrifying true UFO stories, close encounters, and unsolved mysteries from behind the Iron Curtain, hit that LIKE button and subscribe — new dark paths every week.

Featuring perspectives from Dr Stacey A Cohen, Dr Christopher Lieu and Dr Jenny Seligmann, moderated by Dr Lieu, including the following topics: Adjuvant treatment planning for Stage II or III microsatellite instability-high colon cancer (0:00) Roles of circulating tumor DNA (ctDNA), POLE mutations and advanced age in adjuvant treatment planning (6:08) Role of ctDNA in adjuvant treatment planning for Stage III colon cancer (12:31) CME information and select publications

Dr Stacey A Cohen from Fred Hutchinson Cancer Center in Seattle, Washington, Dr Jenny Seligmann from the University of Leeds in the United Kingdom and Dr Christopher Lieu from the University of Colorado Cancer Center in Aurora review clinical findings from the 2026 ASCO Gastrointestinal Cancers Symposium relevant to the management of localized colorectal cancer.CME information and select publications here.

Featuring slide presentations and related discussion from Dr Nikhil I Khushalani, Dr Soo J Park, Dr Vishal Anil Patel and Dr Evan Wuthrick, including the following topics: Introduction (0:00) Current Management of Localized, Locally Advanced and Metastatic Cutaneous Squamous Cell Carcinoma (cSCC) (9:55) Case: A man in his early 70s with cSCC who previously underwent surgery and adjuvant therapy (32:39) Case: A man in his early 60s with cSCC who receives cemiplimab (54:45) Incorporation of Radiation Therapy into the Multidisciplinary Management of cSCC and Basal Cell Carcinoma (BCC) (1:04:24) Case: A man in his early 70s with cSCC who receives radiation therapy after a surgeon expresses concern about the risks of surgery (1:22:15) Case: A man in his late 80s with cSCC who is not a candidate for surgery (1:24:09) Evidence-Based Treatment Strategies for Patients with BCC (1:26:00) Case: A man in his mid sixties with BCC who receives sonidegib (1:36:49) Case: A man in his late 70s with BCC who receives vismodegib (1:38:32) Dermatologic Care for Patients with cSCC and BCC (1:45:09) CME information and select publications

This week's episode will be discussing Pancreatic Cancer with a very special guest Dr. Michael Pishvaian. Dr. Pishvaian is an Associate Professor in GI Oncology at the Johns Hopkins Kimmel Cancer Center, and creator of Tumor Board Tuesday. In part 1, we will focus on risk factors, diagnosis and treatment of localized pancreatic cancer. 

Featuring perspectives from Dr Stacey A Cohen, Dr Christopher Lieu and Dr Jenny Seligmann, moderated by Dr Lieu, including the following topics: Neoadjuvant immunotherapy for localized rectal cancer (0:00) Surveillance in neoadjuvant immunotherapy for localized rectal cancer (8:14) Determining a treatment strategy for resectable colon cancer (12:35) CME information and select publications

Dr Stacey A Cohen from Fred Hutchinson Cancer Center in Seattle, Washington, Dr Jenny Seligmann from the University of Leeds in the United Kingdom and Dr Christopher Lieu from the University of Colorado Cancer Center in Aurora review clinical findings from the 2026 ASCO Gastrointestinal Cancers Symposium relevant to the management of localized colorectal cancer.CME information and select publications here.

Dr Stacey A Cohen from Fred Hutchinson Cancer Center in Seattle, Washington, Dr Jenny Seligmann from the University of Leeds in the United Kingdom and Dr Christopher Lieu from the University of Colorado Cancer Center in Aurora review clinical findings from the 2026 ASCO Gastrointestinal Cancers Symposium relevant to the management of localized colorectal cancer.CME information and select publications here.

Dr Stacey A Cohen from Fred Hutchinson Cancer Center in Seattle, Washington, Dr Jenny Seligmann from the University of Leeds in the United Kingdom and Dr Christopher Lieu from the University of Colorado Cancer Center in Aurora review clinical findings from the 2026 ASCO Gastrointestinal Cancers Symposium relevant to the management of localized colorectal cancer.CME information and select publications here.

Welcome to the Oncology Brothers podcast! In this episode, we discussed the current treatment landscape for prostate cancer, featuring special guest Dr. Scott Tagawa, a GU Medical Oncologist from Weill Cornell Medicine. Listen us on: Spotify: https://open.spotify.com/show/31BXhY9FM4gPWG10WgE11o Follow us on social media: X/Twitter: https://twitter.com/oncbrothers Instagram: https://www.instagram.com/oncbrothers Website: https://oncbrothers.com/ Join us as we explored: The current standard of care for localized prostate cancer, including active surveillance, surgery, and radiation. The significance of ADT and abiraterone in high-risk disease, supported by the STAMPEDE trial. The role of PSMA PET/CT in staging and how it impacts treatment decisions. Treatment options for castration-sensitive and castration-resistant prostate cancer, including the use of ARPi and chemotherapy. The importance of germline and somatic testing, especially with the recent approval of Niraparib for BRCA2-positive disease. Insights on managing side effects and the nuances of patient-centered care in oncology. Whether you're a healthcare professional or someone interested in the latest advancements in cancer treatment, this episode is packed with valuable information to help you stay informed. Don't forget to like, subscribe, and hit the notification bell for more episodes from the Oncology Brothers! #ProstateCancer, #ADT, #PSMA, #PARPinhibitor, #OncologyBrothers

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China is on alert as a fresh wave of rain and snow is expected over the next three days, potentially causing travel and tourism disruptions following the Spring Festival holiday. While less widespread and intense than recent weather events, the precipitation warrants attention.气象部门发出预警，预计未来三天我国将迎来新一波雨雪天气，可能导致春节假期结束后交通和旅游出现中断。虽然此次过程的强度和影响范围不及之前，但仍需引起注意。On Sunday, significant snowfall affected Shanxi, Hebei and Henan provinces, while heavy rains drenched much of southern China. The National Meteorological Center forecasts an eastward shift in snowfall, bringing light to moderate accumulations to the Inner Mongolia autonomous region, eastern and northern North China, most of Northeast China and the northern Xinjiang Uygur autonomous region. Inner Mongolia and Heilongjiang province may experience heavy snow and localized blizzards.3月1日，山西、河北和河南等地出现显著降雪，与此同时，强降雨影响了南方大部地区。中央气象台预计，降雪区域将向东移动，内蒙古自治区、华北中东部、东北地区大部和新疆维吾尔自治区北部等地将迎来小到中雪，累计降雪量一般有1～3毫米。其中，内蒙古和黑龙江等地局地可能出现大雪或暴雪。Simultaneously, South China is bracing for heavy rainfall, with moderate to heavy precipitation expected in the southern provinces of Fujian, Guangdong, Hainan, the Guangxi Zhuang autonomous region and Taiwan. Localized downpours and possible thunderstorms are also anticipated.与此同时，华南地区将迎来强降雨，预计福建、广东、海南、广西壮族自治区和台湾等南方省份将有中到大雨。局地可能出现暴雨和雷暴天气。Offshore, strong winds will affect eastern sea areas due to an intensifying cyclone entering the sea near Jiangsu and Zhejiang provinces. On Tuesday, gusts reaching 24.5 meters per second are predicted for the Yellow Sea, East China Sea, Taiwan Strait and parts of the South China Sea.在近海区域，由于入海气旋加强，江苏和浙江附近海域将出现大风。周二，预计黄海、东海、台湾海峡和南海部分海域将出现阵风达每秒24.5米的大风。Despite these localized events, forecasters predict no large-scale rain or snow across China this week, with precipitation expected to be scattered and generally light.预报员指出，尽管有这些局地天气事件，但预计本周全国范围内不会出现大范围的雨雪天气，降水总体较为分散，强度一般。However, persistent rain in eastern Southwest China will create slippery roads and reduce visibility, requiring public vigilance during travel.然而，我国西南地区东部持续的阴雨天气将导致道路湿滑和能见度降低，公众出行需注意安全。Northern China will experience a brief warming trend before a cold front arrives on Wednesday and Thursday. Conversely, the south will cool down, providing relief from recent warmth. Daytime highs in Haikou, Hainan, are expected to drop to 20 C by Wednesday.北方地区在周三和周四冷空气到来之前将经历短暂的回暖过程。与之相对，南方地区将迎来降温，使近日的回温天气得到缓解。到周三时，海南海口的白天最高气温预计将降至20摄氏度。In addition, most of China's northern winter wheat region is projected to experience near-average temperatures and 10 to 30 millimeters of rainfall over the next 10 days, which will improve soil moisture and aid the resurgence of winter wheat growth, according to agricultural forecasts.此外，农业气象预报显示，未来10天，我国北方冬麦区大部气温接近常年同期，降水量有10～30毫米。降水将有效改善土壤墒情，利于冬小麦返青生长。The Yangtze River Delta, South China and Southwest China are expected to see near-average or slightly above-average temperatures with 10 to 50 mm of precipitation, benefiting reservoir storage and providing water for spring planting, it added.预报还指出，长江中下游、华南及西南地区南部等地气温接近常年同期或偏高，降水量有10～50毫米，利于增加库塘蓄水和保障春播用水。precipitation /prɪˌsɪpɪˈteɪʃən/降水drench /drentʃ/湿透，浸透National Meteorological Center /ˈnæʃənəl ˌmiːtiərəˈlɒdʒɪkəl ˈsentər/ 中央气象台localized blizzards /ˈləʊkəlaɪzd ˈblɪzədz/局地暴雪downpour /ˈdaʊnpɔː/倾盆大雨，暴雨cyclone /ˈsaɪkləʊn/气旋gust /gʌst/一阵强风，阵风vigilance /ˈvɪdʒɪləns/警惕，警戒resurgence /rɪˈsɜːdʒəns/复苏，再现

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Featuring perspectives from Dr Stacey A Cohen, Dr Christopher Lieu and Dr Jenny Seligmann, moderated by Dr Lieu, including the following topics:  Introduction (0:00) Neoadjuvant Treatment for Localized Colorectal Cancer (CRC) — Dr Seligmann (2:39) Emerging Novel Approaches to Adjuvant Treatment for Localized CRC — Dr Lieu (33:18) Role of Circulating Tumor DNA Testing in Localized CRC — Dr Cohen (59:43) CME information and select publications

Dr Stacey A Cohen from Fred Hutchinson Cancer Center in Seattle, Washington, Dr Jenny Seligmann from the University of Leeds in the United Kingdom and Dr Christopher Lieu from the University of Colorado Cancer Center in Aurora review clinical findings from the 2026 ASCO Gastrointestinal Cancers Symposium relevant to the management of localized colorectal cancer.CME information and select publications here.

Dr Stacey A Cohen from Fred Hutchinson Cancer Center in Seattle, Washington, Dr Jenny Seligmann from the University of Leeds in the United Kingdom and Dr Christopher Lieu from the University of Colorado Cancer Center in Aurora review clinical findings from the 2026 ASCO Gastrointestinal Cancers Symposium relevant to the management of localized colorectal cancer.CME information and select publications here.

In its waning years, the Galactic Republic endured less like a golden age than a prolonged twilight, its ancient institutions still standing but riddled with unseen fractures. Corruption seeped into the Senate beneath layers of procedure and decorum, while corporate interests and regional power blocs bent law into currency. Localized conflicts flared along distant borders, dismissed as anomalies even as they multiplied, and faith in the Republic's ability to protect its citizens ebbed in the shadow of inaction. Become a patron to get access to the bonus episodes or support the show through Paypal and bitcoin! You can also check out our merch on Redbubble. Don't forget to also connect with us on Facebook, Instagram, X.com and Discord! Find all of our links here: https://doras.to/starlores Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Tyson Singer (Head of Tech & Platforms @ Spotify) joins us to unpack how Spotify is transforming its product development lifecycle across creation, experimentation and maintenance to shift from "localized speed" to "systematic speed." We explore why the industry's current obsession with the "Build It" phase of development is shortsighted, and how Spotify is aggressively deploying AI in the "Think It" (prototyping/strategy) and "Maintain It" (fleet management) phases. Tyson also details the internal tools driving this shift, including AiKA and Honk, and shares why the future of engineering relies on moving from I-shaped specialists to T-shaped generalists. ABOUT TYSON SINGERTyson Singer is the SVP of Technology & Platforms at Spotify, where he leads technology infrastructure, developer experience, cybersecurity, and finance IT. Tyson is the executive behind Spotify's internal developer portal, Backstage, and Spotify's experimentation system, Confidence, which are now both commercially available. He has a background as an engineer, architect, and product lead, and he holds a Master's in Computer Science from Stanford University. Tyson is also an avid outdoor adventurer. This episode is brought to you by Retool!What happens when your team can't keep up with internal tool requests? Teams start building their own, Shadow IT spreads across the org, and six months later you're untangling the mess…Retool gives teams a better way: governed, secure, and no cleanup required.Retool is the leading enterprise AppGen platform, powering how the world's most innovative companies build the tools that run their business. Over 10,000 organizations including Amazon, Stripe, Adobe, Brex, and Orangetheory Fitness use the platform to safely harness AI and their enterprise data to create governed, production-ready apps.Learn more at Retool.com/elc SHOW NOTES:Tyson's 9-year journey @ Spotify: From the "crucible" of hyper-growth to leading Tech & Platforms (3:46)The pivot from "localized speed" to "systematic speed" (7:27)Core principles of Spotify's Platform org: Partnering with customers & "Taking the pain away" (10:37)The "Think it, Build it, Ship it, Tweak it" lifecycle framework & why the industry obsession with "Build It" (coding agents) is missing the bigger picture (14:57)How Spotify is investing in the "Think It" phase: AI prototyping with deep business context (16:49)AiKA (AI Knowledge Assistant): Context engineering for humans and bots (18:47)"Honk": Spotify's internal framework for large-scale automated code changes (22:17)Addressing the decline of code quality and the bottleneck of human PR reviews (25:50)Probabilistic vs. Deterministic code reviews: A new approach to quality checks (29:43)Identifying bottlenecks to company value outside of R&D (Legal, Licensing, etc.) (32:12)Why systems change is fundamentally about people and identity shifts (35:57)Rapid fire questions (38:49) This episode wouldn't have been possible without the help of our incredible production team:Patrick Gallagher - Producer & Co-HostJerry Li - Co-HostNoah Olberding - Associate Producer, Audio & Video Editor https://www.linkedin.com/in/noah-olberding/Dan Overheim - Audio Engineer, Dan's also an avid 3D printer - https://www.bnd3d.com/Ellie Coggins Angus - Copywriter, Check out her other work at https://elliecoggins.com/about/ Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

We had a kwentuhan with WEHLO last Philippine Startup Week 2025!WEHLO is a localized weather, environment, and hydromet monitoring system for more precise forecasts.This episode is recorded live at the Philippine Innovation Hub in Marikina City.In this episode:00:00 Introduction02:06 Ano ang WEHLO?28:22 How can listeners find more information?WEHLOWebsite: https://wehlo.netFacebook: https://facebook.com/wehlotechPHILIPPINE STARTUP WEEKWebsite: https://phstartupweek.comFacebook: https://facebook.com/PhilippineStartupWeekTHIS EPISODE IS CO-PRODUCED BY:Kredit Hero: ⁠https://kredithero.com/⁠Yspaces: ⁠https://knowyourspaceph.com⁠Twala: ⁠https://twala.io⁠Symph: ⁠https://symph.co⁠Secuna: ⁠https://secuna.io⁠SkoolTek by Edfolio: ⁠https://skooltek.co⁠MaroonStudios: ⁠https://maroonstudios.com⁠CompareLoans: ⁠http://compareloans.ph⁠CHECK OUT OUR PARTNERS:Ask Lex PH Academy: ⁠https://asklexph.com⁠ (5% discount on e-learning courses! Code: ALPHAXSUP)ArkoTech: ⁠https://www.arkotechspacesolutions.com/⁠DVCode Technologies Inc: ⁠https://dvcode.tech⁠NutriCoach: ⁠https://nutricoach.com⁠Argum AI: ⁠http://argum.ai⁠PIXEL by Eplayment: ⁠https://pixel.eplayment.co/auth/sign-up?r=PIXELXSUP1⁠ (Sign up using Code: PIXELXSUP1)School of Profits: ⁠https://schoolofprofits.academy⁠Founders Launchpad: ⁠https://founderslaunchpad.vc⁠Hier Business Solutions: ⁠https://hierpayroll.com⁠Agile Data Solutions (Hustle PH): ⁠https://agiledatasolutions.tech⁠Smile Checks: ⁠https://getsmilechecks.com⁠CloudCFO: ⁠https://cloudcfo.ph⁠ (Free financial assessment, process onboarding, and 6-month QuickBooks subscription! Mention: Start Up Podcast PH)Cloverly: ⁠https://cloverly.tech⁠BuddyBetes: ⁠https://buddybetes.com⁠HKB Digital Services: ⁠https://contakt-ph.com⁠ (10% discount on RFID Business Cards! Code: CONTAKTXSUP)Hyperstacks: ⁠https://hyperstacksinc.com⁠OneCFO: ⁠https://onecfoph.co⁠ (10% discount on CFO services! Code: ONECFOXSUP)Wunderbrand: ⁠https://wunderbrand.com⁠Uplift Code Camp: ⁠https://upliftcodecamp.com⁠ (5% discount on bootcamps and courses! Code: UPLIFTSTARTUPPH)START UP PODCAST PHYouTube: ⁠https://youtube.com/startuppodcastph⁠Spotify: ⁠https://open.spotify.com/show/6BObuPvMfoZzdlJeb1XXVa⁠Apple Podcasts: ⁠https://podcasts.apple.com/us/podcast/start-up-podcast/id1576462394⁠Facebook: ⁠https://facebook.com/startuppodcastph⁠Patreon: ⁠https://patreon.com/StartUpPodcastPH⁠PIXEL: ⁠https://pixel.eplayment.co/dl/startuppodcastph⁠Website: ⁠https://phstartup.online⁠This episode is edited by the team at: ⁠https://tasharivera.com⁠

Viral Skin Conditions: Exam Organization Viral dermatologic conditions are best approached by age, distribution, and systemic involvement rather than by memorizing individual viruses. Confusion on exams often occurs when pediatric viral exanthems are tested against one another. Categories for exam organization:• Pediatric systemic viral patterns (viral exanthems, hand-foot-and-mouth disease, varicella)• Localized viral lesions (HSV, molluscum […] The post 151 Childhood Viral Rashes Made Simple – Exanthems, HFMD, Chickenpox & the Patterns That Show Up on PANCE appeared first on Physician Assistant Exam Review.

Many entrepreneurs and marketers feel like they've missed the boat on short-form video. The common thought: "That worked a few years ago, but it's too saturated now." But what if that's a myth? Colin Landforce, founder of Cut30, argues that with a unique perspective and consistent effort, anyone can achieve massive results, regardless of follower count. He's seen students with under 1,000 followers generate tens of thousands in revenue, proving you don't need millions of views to make a significant business impact. Colin reveals his three-step framework for taking short-form video seriously, alongside the critical role of hooks, and how to simplify your strategy to win big.Timestamps:00:00 Intro: The biggest opportunity in media01:14 Why short-form video is a generational opportunity02:26 Breaking the myth of saturation05:48 The power of small audiences10:48 Why founders should create their own short-form content12:50 The shift from side project to serious business14:39 Break the seal - just start17:08 How to make your first simple "one shot" video20:25 Learn the edit - basic chops in CapCut23:33 The importance of efficiency in short-form content29:26 Do it again tomorrow - consistency is key34:13 How to generate an endless supply of content ideas36:03 The three keys to a compelling hook37:41 The "everyone's been asking me" hook40:28 The impact of visual hooks beyond motorcycle crashes43:01 The power of props in visual hooks48:16 Brainstorming short-form content from this podcast episode50:45 Crafting a tight, efficient short-form video example54:51 Why short-form is Colin's primary driver for any businessIf you enjoyed this episode, please like and subscribe, share it with your friends, and leave a review. I read every single one.Learn more about the podcast: https://nathanbarry.com/showFollow Nathan:Instagram: https://www.instagram.com/nathanbarryLinkedIn: https://www.linkedin.com/in/nathanbarryX: https://twitter.com/nathanbarryYouTube: https://www.youtube.com/@thenathanbarryshowWebsite: https://nathanbarry.comKit: https://kit.comFollow Colin:Instagram: https://www.instagram.com/landforceTikTok: https://www.tiktok.com/@landforce_LinkedIn: https://www.linkedin.com/in/colinlandforceCut30: https://course.cut30.coWebsite: https://landforce.comFeatured in this episode:Kit: https://www.kit.comCut30: https://course.cut30.coHighlights:02:15 The myth of saturation in short-form video06:02 Small audience, huge business impact14:08 Short-form video: the biggest opportunity in media24:41 The accordion method for content efficiency32:36 Track inputs, not outputs, for personal growth52:12 Words to make your hook more efficient56:45 Localized algorithms for niche businesses

For Episode 230, we welcome Djimo Serodio, Founder of Silvi, and Jon Ruth, Co-Founder of the Climate Coordination Network, two leaders helping reimagine how the world funds and verifies ecological restoration.We unpack the newly launched Bioregional Reforestation Grants Round, the largest blockchain-native, outcomes-based reforestation funding mechanism to date, and explore why this may be a blueprint for the next era of regenerative climate finance.You'll learn:

The salient point of today's discourse revolves around the imminent weather developments across the United States, particularly emphasizing the marginal risk of excessive rainfall along the central Gulf coast and the anticipated atmospheric river affecting the Pacific Northwest. I elucidate the potential for localized flash flooding in coastal regions due to persistent showers. Concurrently, I provide updates regarding winter weather advisories and warnings for several states, including Michigan and Colorado, where hazardous travel is expected due to heavy snowfall. Additionally, I draw attention to the coastal flood advisories in various regions, underscoring the need for vigilance as high tides may lead to minor inundation. This comprehensive weather briefing serves to prepare our audience for the diverse meteorological challenges that lie ahead.Takeaways:* The Weather Prediction Center has issued a Day One marginal risk for excessive rainfall along the central Gulf Coast, indicating possible weather-related impacts. * Localized flash flooding is anticipated in areas where persistent showers develop near coastal regions, necessitating vigilance among residents. * A strong atmospheric river event is forecasted for the Pacific Northwest early next week, which may influence local weather patterns significantly. * Winter weather advisories remain active across multiple states, including Alaska and Michigan, highlighting ongoing hazardous conditions due to snow and freezing temperatures. * Coastal flood advisories have been issued for various regions, including North Carolina and Oregon, in response to high tide events that may lead to minor inundation. * Overall, careful monitoring of weather patterns and advisories is essential as conditions continue to evolve across the United States. Sources[WPC Day 1 ERO | https://www.wpc.ncep.noaa.gov/qpf/ero.php?day=1&opt=curr][NWS Mobile | https://www.weather.gov/mob/].NCEP Weather Prediction Center+1][NWS Anchorage | https://www.weather.gov/afc].[NWS LOX | https://forecast.weather.gov/wwamap/wwatxtget.php?cwa=usa&wwa=high+surf+advisory][NWS SF Bay Area | https://www.weather.gov/mtr/][NWS Grand Junction | https://forecast.weather.gov/showsigwx.php?product1=Winter+Weather+Advisory&firewxzone=COZ205][NWS LIX | https://www.weather.gov/lix/][WPC | https://www.wpc.ncep.noaa.gov/qpf/ero.php?day=1&opt=curr][NWS APX | https://www.weather.gov/apx/][NWS Missoula | https://forecast.weather.gov/wwamap/wwatxtget.php?cwa=mso&wwa=winter+weather+advisory][NWS Buffalo | https://www.weather.gov/buf/BUFHWOBUF][NWS WWA (ILM) | https://forecast.weather.gov/wwamap/wwatxtget.php?cwa=usa&wwa=coastal+flood+advisory][NWS Wilmington | https://www.weather.gov/ilm/][NWS Portland | https://www.weather.gov/wwamap/wwatxtget.php?cwa=pqr&wwa=all][NWS Nashville | https://forecast.weather.gov/wwamap/wwatxtget.php?cwa=usa&wwa=winter+weather+advisory][NWS EWX AFD | https://forecast.weather.gov/product.php?issuedby=EWX&product=AFD&site=EWX][NWS EWX | https://www.weather.gov/ewx/][NWS WWA | https://forecast.weather.gov/wwamap/wwatxtget.php?cwa=usa&wwa=coastal+flood+advisory][NWS Seattle | https://www.weather.gov/sew/][WPC | https://www.wpc.ncep.noaa.gov/discussions/pmdepd.html] This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit emnetwork.substack.com/subscribe

In this episode of the Scaling Japan Podcast, we welcome Ignacio Dávalos, Content Strategy Director at AIM B2B (a Custom Media company), and an experienced marketer who has led multi-channel B2B and B2C strategies for global brands like L'Oréal, Gengo, and Lionbridge.Ignacio breaks down how LINE Ads work in Japan, why they are so effective across multiple industries, and how the platform differs from Western advertising tools like Meta. He explains the ad formats that perform best, how targeting works using Yahoo Japan's data, and why the LINE Official Account is essential for converting and nurturing leads.He also shares B2C and B2B case studies, full-funnel strategies, CRM integration recommendations, and the most common mistakes foreign companies make when using LINE Ads.If you're a marketer, founder, or advertiser looking to grow in Japan, this episode gives you a tactical, platform-specific playbook for succeeding with LINE.This episode is sponsored by Custom Media, Tokyo's leading integrated marketing and PR agency since 2008, helping global brands expand across Japan and APAC.They can help you with:Localized storytelling to build trust in Asian marketsStrategic performance marketing (LINE Ads, LinkedIn Ads, GEO, SEO)Account-based marketing (ABM) and paid mediaHubSpot-certified CRM & marketing automationData-driven implementation with cultural expertise

In this episode of the Scaling Japan Podcast, we welcome Ignacio Davalos, Content Strategy Director at AIM B2B (a Custom Media company) and an experienced marketer who has led full-funnel B2B and B2C programs for brands like L'Oréal, Gengo, and Lionbridge.Ignacio breaks down how LinkedIn is actually used in Japan, who the real users are, what types of campaigns perform well, and why Western lead-generation playbooks often fail when applied to the Japanese market. He shares practical insights on localization, targeting, tool integrations, and campaign structure, backed by multiple real case studies.If you're a marketer, consultant, or B2B advertiser looking to run LinkedIn campaigns in Japan, this episode gives you a tactical, Japan-specific guide to what works and what doesn't.This episode is sponsored by Custom Media, Tokyo's leading integrated marketing and PR agency since 2008, helping global brands expand across Japan and APAC.They can help you with:Localized storytelling to build trust in Asian marketsStrategic performance marketing (including LinkedIn Ads)Account-based marketing (ABM), paid media, GEO, and SEOHubSpot-certified CRM and marketing automationData-driven implementation with cultural expertiseLearn more about AIM B2B here: https://hi.switchy.io/h7TM 00:29 – Introduction 00:56 – Guest Introduction 03:03 – LinkedIn user numbers & growth 07:09 – User demographics in Japan 11:41 – Competitors to LinkedIn 14:10 – How Western companies use LinkedIn 15:50 – How Japan uses LinkedIn differently 18:34 – Japanese vs Western tool integrations 26:30 – French newspaper case study 28:50 – Strengths of LinkedIn as an ad platform 34:39 – Cybersecurity case study 37:29 – How to build a successful awareness-phase campaign 40:10 – Localization of messaging & targeting 48:23 – Japanese vs English ads 49:50 – Pitfall: MBA campaign with low results 51:16 – Common mistakes in follow-up and nurturingConnect with Ignacio Davalos on LinkedIn – linkedin.com/in/ignaciodavalos Link to GEO Strategy Online Webinar from AIM B2B: https://aim-b2b.com/lp/the-master-generative-engine-optimization-strategy/ Looking to take your business to the next level?Let our host Tyson Batino help you scale your company from $100,000 to $10,000,000 with personalized coaching and advisory.

In this week's episode of The Energy Code, Dr. Mike Belkowski returns to the roots of his red-light research—breaking down four powerful new studies that reveal just how multifaceted photobiomodulation truly is.   From boosting mitochondrial function and improving sleep to reducing chronic pain and supporting mental health, Dr. Mike explores the data behind red and near-infrared light and what it means for athletes, biohackers, and anyone pursuing optimal energy and longevity.   Dr. Mike dives into: A systematic review on whole-body red-light therapy for exercise performance and recovery The connection between melatonin production and mitochondria How red light can relieve fibromyalgia pain and calm an over-sensitized nervous system A study showing transcranial near-infrared light can reduce anxiety, depression, and drug cravings The latest FDA-approved findings for age-related macular degeneration   This deep-dive connects the science to real-world strategies—helping listeners understand how to personalize light therapy for maximum mitochondrial, mental, and cellular benefits. Key Topics Covered The myth of “more light equals better results” Why localized red-light therapy outperforms full-body setups for muscle recovery How red light enhances melatonin and circadian alignment for deeper sleep Using red light to calm the nervous system and reduce systemic inflammation New clinical results showing brain-based red light reduces depression and cravings FDA authorization for light therapy in macular degeneration How to calculate your optimal dosage with BioLight's free treatment calculator Key Quotes from Dr. Mike Belkowski   “Your mitochondria are environmental sensors — when they see the wrong light, they know it.” “Localized light on target tissue beats whole-body treatments when it comes to performance.” “Red light therapy can calm an overstimulated nervous system and retrain your pain pathways.” “The more we standardize light protocols, the more consistent and powerful the results will be.” Episode Timeline   00:00 – Morning sunrise + intro 02:30 – What's new in the mitochondrial matrix 07:00 – BioMinerals discount announcement 08:00 – Study #1: Whole-body red light for performance 15:00 – Why dosage and location matter 16:00 – Red light, melatonin & sleep quality 19:00 – Red light's stress-reducing parasympathetic effects 23:00 – Study #2: Fibromyalgia and chronic pain reduction 30:00 – How red light calms sensitized nerves 33:00 – Study #3: Transcranial red light for mood & craving 36:00 – Near-infrared brain protocols explained 37:00 – Study #4: Red light for macular degeneration 44:00 – Why research results can appear contradictory 46:00 – Final thoughts: dosage, nuance, and mitochondrial optimization

In this episode of the Heart of Rural America podcast, Amanda Radke and Chris Earl discuss the implications of recent comments made by President Donald Trump regarding beef pricing. They explore the challenges faced by ranchers, the role of government in agriculture, and the importance of advocating for the beef industry. The conversation delves into the genetics of beef production, the monopolization of the beef market, and the need for localized processing facilities. The episode emphasizes the importance of consumer awareness and the necessity for ranchers to stand up for their interests in a changing agricultural landscape.TakeawaysGovernment involvement in pricing can be detrimental to ranchers.Ranchers face challenges from monopolization in the beef industry.Consumer demand for beef remains strong despite price concerns.Genetics play a crucial role in the quality of beef production.Localized processing facilities are essential for the future of ranching.Advocacy is necessary for ranchers to protect their interests.The beef industry is facing a crisis due to external pressures.Ranchers need to leverage their expertise to influence policy.The future of ranching depends on consumer support and awareness.Chapters00:00 Introduction to the Heart of Rural America02:06 The Role of Government in Beef Pricing03:48 Concerns Over Beef Prices and Market Dynamics12:10 Genetics and Quality in Beef Production17:19 Monopoly in the Beef Industry22:40 The Need for Localized Processing28:01 Advocacy and the Future of RanchingPresented by Bid on Beef | CK6 Consulting | CK6 Source | Real Tuff Livestock Equipment | Ambrook | Redmond RealSalt | Dirt Road Radio | All American Angus Beef | Radke Land & CattleTry a one-month trial with Ambrook for free here: ambrook.com/radkeUse code RADKE for $10 off your next All American Angus Beef order at www.BidOnBeef.comSave on Redmond Real Salt with code RADKE at https://shop.redmondagriculture.com/Check out Amanda's agricultural children's books here: https://amandaradke.com/collections/amandas-books

Localized journalism played a pivotal role in breaking through the silence and inertia that surrounded the Epstein investigation for years. National outlets often overlooked or downplayed the story, but local reporters—particularly in Florida—kept pushing. The Miami Herald's investigative series “Perversion of Justice” became a turning point, laying bare the sweetheart deal Epstein received and how officials swept his crimes under the rug. By digging into court records, interviewing survivors, and pressing local authorities, these journalists exposed the corruption and failures of law enforcement in a way that reverberated nationally. Survivors later credited these local stories with giving them a voice when no one else would.Localized journalism played a pivotal role in breaking through the silence and inertia that surrounded the Epstein investigation for years. National outlets often overlooked or downplayed the story, but local reporters—particularly in Florida—kept pushing. The Miami Herald's investigative series “Perversion of Justice” became a turning point, laying bare the sweetheart deal Epstein received and how officials swept his crimes under the rug. By digging into court records, interviewing survivors, and pressing local authorities, these journalists exposed the corruption and failures of law enforcement in a way that reverberated nationally. Survivors later credited these local stories with giving them a voice when no one else would.to contact me:bobbycapucci@protonmail.com

In Episode 334, Kestrel welcomes Emily Mikhaiel, the cofounder and creative director of Nazeerah, to the show. A clothing brand inspired by the legacy of her grandmother, Nazeerah supports organic and regenerative farming practices to honor Egyptian cotton, and produces locally in Egypt to maintain direct relationships with their suppliers and reduce their carbon footprint. “There really wasn't waste while my father was growing up. Everything was either composted or if it was metal, it was recycled or reused or repurposed. If a garment was no longer wearable, they'd cut it up into strips and weave carpets out of it. And once the carpet was no longer usable, they'd cut it up again and compost it. So using that knowledge and thinking, you know, as a society, we've existed without plastics for millennia. Why can't we return to that and draw inspiration from that in our design?” -Emily SEPTEMBER THEME —WHEN *REGENERATIVE* MEANS SO MUCH MORE THAN JUST A BUZZWORD This week's episode is focused largely on a regenerative approach to making clothes – one that includes thinking about the end of life of the garment at the design process, where organic cotton farming is centered, not only to help maintain soil health, but also to enhance biodiversity and restore carbon to the soil, and where local production is prioritized. Without sounding like a broken record, it's important to acknowledge how this word – regenerative – has undoubtedly become another buzzword that's taken fashion by storm. We've seen countless brands integrate it into their marketing messaging, and it's becoming more and more utilized across the space as the “new way” to talk about building a more sustainable brand.  HOWEVER – it's very key to note that regenerative is by no means a new concept. As we've touched on in past episodes, it is rooted in Indigenous knowledge, in traditional ways of farming and ancestral ways of growing plants and being in conversion with the Earth. This week's guest has deep family ties to cotton and garment making in Egypt. As she shares with us, Egypt has a unique history connected to cotton farming that for generations, was intrinsically linked to the natural rhythms of the Nile River.  Through her brand, she is not only honoring her ancestors' connection to the land, but also supporting farmers who are reclaiming what regenerative cotton farming can look like today.  Nazeerah Website Follow Nazeerah on Instagram