Podcasts about iic

Send us a textIn this episode, we share a conversation with me (Avantika Mathur) on Dani Fankhauser's Spirit Doggies Podcast. Here's a little bit more about the episode, from that podcast:"If your first thought was that animal communication doesn't exactly sound science-based, you wouldn't be alone.This week's guest combined her drive for a purposeful career with her academic roots to become a pioneer in the field of animal communication research. She set aside her own initial doubts and put on her researcher hat to find out.This interview absolutely blew my mind! There's already so much work underway in understanding and making practical use of animal communication, on both small and large scales.Avantika Mathur is an academic researcher with a master of science in Global Health, co-host of the Animals & Us podcast, and is currently completing a research fellowship focused on Intuitive Interspecies Communication. She's a trailblazer in this space, both in coordinating events and editing for academic journals on the topic.Learn more about the podcast here: ⁠dogdeities.comIn this episode: Avantika's career pivot into studying animal communicationAdoption story of her first dog, SimbaThe current academic research around animal communicationWhat humans can learn from animals, and their perception of us and our contributions to the globe (!!)How intuitive interspecies communication (IIC) can help address major global issues like climate change, without fear or shame tactics"

Why A Certificate Will Protect You In Self Defense Register for our upcoming IIC on November 15-17 in New Jersey. Participating via Zoom will also be available!

In this  episode of Animals & Us - Voices of a New Paradigm, we welcome the wonderful Dr. Estella Carolye Kuchta, a passionate researcher and educator. With her recent PhD completion, Dr. Kuchta explores the transformative potential of love in our understanding of the natural world and our connections with it.Join us as we jump into her fascinating research on intuitive interspecies communication (IIC) and how love serves as a vital bridge in fostering deeper connections with animals, particularly trees. Dr. Kuchta shares her insights on how each being possesses intrinsic value, not only for their contributions to our lives but simply for existing.Here's what we talked about:The Role of Love in Interspecies Communication: Dr. Kuchta shared her research on how love enables intuitive communication with animals, particularly trees. She believes that by tuning into love, we can become more responsible and caring members of Earth.Re-envisioning Education: We discussed the need for a paradigm shift in educational practices, moving beyond traditional "green" initiatives to address the deeper values embedded in our systems.Messages from Trees: Dr. Kuchta revealed the insights she received from trees about how to communicate with them and the important messages they want to share with humanity.Skepticism and Fear: She shared a story about a friend who transitioned from skepticism to understanding, highlighting the often-fear-based roots of skepticism regarding intuitive communication.Future Vision for Education: Dr. Kuchta articulated her vision for integrating love and environmental awareness into educational systems, emphasizing the importance of changing how we think about our relationships with nature.About Dr. Kuchta:Dr. Estella Carolye Kuchta teaches ecocriticism and research writing at Langara College in Vancouver, Canada. Her doctoral research investigated the epistemological potential of love and the redefining of love from an ecological perspective. She is the coauthor with Sean Blenkinsop of Ecologizing Education: Nature-Centered Teaching for Cultural Change (Cornell, 2024). Her ecocritical research into Canadian love stories resulted in the novel Finding the Daydreamer(Elm Books, 2020). She has worked as a research assistant to Dr. Gabor Maté (MD), an editor for Susila Dharma International, and an intern for the CBC Radio, and is a long-time member of the International Love Research Network and the interfaith group Subud. 

The Common Misconception of Knee Strikes in TKD Register for our upcoming IIC on November 15-17 in New Jersey. Participating via Zoom will also be available!

Etiquette that Your Taekwon-Do Students Need Register for our upcoming IIC on November 15-17 in New Jersey. Participating via Zoom will also be available!

Why The Leg Has To Be Bent on These Kicks Register for our upcoming IIC on November 15-17 in New Jersey. Participating via Zoom will also be available!

Do I Hold Out a Twisting Kick in Patterns Register for our upcoming IIC on November 15-17 in New Jersey. Participating via Zoom will also be available!

What is an IIC and Where Can You Join Next! Register for our upcoming IIC on November 15-17 in New Jersey. Participating via Zoom will also be available!

Why do we do a 360 Jump? Register for our upcoming IIC on November 15-17 in New Jersey. Participating via Zoom will also be available!

Industrial Talk is onsite at IoT Solutions World Congress and talking to Marc Tarrago, Event Director at Fira Barcelona about "Bringing global leaders together in digital transformation and cybersecurity!". Scott MacKenzie hosts an industrial podcast celebrating industry professionals and their innovations. At the IoT Solutions World Congress in Barcelona, he interviews Marc Tarrago, the event organizer, about the success of the event. Marc highlights the international focus, with delegations from China, India, and the US, and the shift in program direction to the International Society of Automation. The event is divided into four rooms addressing tech-enabled transformation, climate change, standards and regulations, and IoT security. The importance of cybersecurity with the growing number of connected devices is emphasized. The team's efforts and the positive feedback from attendees are praised, with plans to continue covering healthcare and sustainability in future events. Action Items [ ] Analyze trends and technologies to cover for next year's event. [ ] Look into potentially adding healthcare as a focus vertical. [ ] Promote and provide information on next year's event. Outline Welcome to Industrial Talk Podcast Scott MacKenzie introduces the Industrial Talk podcast, emphasizing its focus on industry professionals and their innovations. The podcast aims to highlight the efforts of men and women in various industries. Scott encourages listeners to join the podcast and celebrates the industry professionals who make the world a better place. The podcast is broadcasting from the IoT Solutions World Congress in Barcelona, Spain. Introduction of Mark and Event Overview Scott introduces Mark, the head of the event, and asks him about his experience. Marc expresses excitement and satisfaction with the event, noting its success and positive feedback. Scott mentions the shift from theoretical AI discussions to practical applications. Mark highlights the international focus of the event, with delegations from China, India, and the US. International Focus and Program Changes Marc explains the effort to make the event more international, including bringing in delegations from various countries. The program direction has shifted from the IIC to the International Society of Automation (ISA). Scott praises the event's layout and the level of knowledge gained from attending. Marc outlines the four different rooms focused on specific challenges, including tech-enabled transformation, climate change, standards and regulations, and IoT security. Digital Transformation and Cybersecurity Scott discusses the importance of digital transformation and connected strategies in manufacturing. Marc emphasizes the connection between IoT devices, data collection, and cybersecurity. The event aims to address the growing number of connected devices and the need for robust cybersecurity measures. Scott appreciates the comprehensive approach to cybersecurity at the event. Disruptive Technologies and Future Trends Marc mentions the inclusion of disruptive technologies like AI, digital twin, machine learning, and computing in the event. Scott inquires about the current state of technology and innovation, with Mark agreeing that they are still at the beginning of realizing the benefits. Scott praises the team's efforts in organizing the event and the positive feedback from participants.

Meaning of the ITF Logo & Should We Change It Register for our upcoming IIC on November 15-17 in New Jersey. Participating via Zoom will also be available!

Who Owns the ITF Logo? Register for our upcoming IIC on November 15-17 in New Jersey. Participating via Zoom will also be available!

Sam-Il - Two Techniques That Aren't How They Are Normally Performed Register for our upcoming IIC on November 15-17 in New Jersey. Participating via Zoom will also be available!

In this episode, we sit down with Dr. Vanessa Wjingaarden, a passionate researcher with a curious mind and a love for animals. She's a social anthropologist and filmmaker who has spent years studying the lives of indigenous communities, particularly in East-African Maasailand. Her award-winning documentaries have shed light on the rich cultural lives of the Maasai people and their deep connection to their environment and animals.In this episode, Vanessa shares her fascinating journey into the world of intuitive interspecies communication (IIC). We talk about her research with animal communicators across Europe and Africa, exploring how different cultures perceive and practice IIC. Vanessa also discusses her groundbreaking new research project, "Animal Communicators: Intuitive Communication as a Key to Dialogic Multispecies Methods," which aims to bridge the gap between nature and culture by engaging animals as active participants in research.Join us as Vanessa shares the challenges she has faced, and the profound insights she has gained. From her time with the Maasai to her current work on IIC, Vanessa's story is one of passion, perseverance, and a deep commitment to understanding the world around us.Whether you're an academic, a practitioner of animal communication, or simply curious about the possibilities of intuitive connections with animals, we hope you will leave this episode feeling curious, excited and inspired about what's on the horizon with IIC research. Tune in to hear Vanessa's unique perspective and learn more about the exciting future of interspecies communication. She talks about her advice for those who want to explore their own IIC abilities, her vision for the future of her research, and how you can connect with her and follow her innovative work. 

 - Nền kinh tế Việt Nam tiếp đà hồi phục sau dự báo tăng trưởng quý II- Các "đại bàng" công nghệ Đài Loan muốn chuyển sản xuất sang VN- Cuộc đua tăng vốn của các công ty chứng khoán trong nước Chủ đề : chứng khoán, cuộc đua --- Support this podcast: https://podcasters.spotify.com/pod/show/vov1kd/support

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In this episode, we discuss how models help us more fully understand Catholic personal formation by showing distinctions and relationships among human formation, spiritual formation, intellectual formation, and pastoral formation. Next, we examine my new model that views formation through a mathematical lens. I explain these each dimension of formation, likening it to a branch of mathematics, and draw from Pastores Dabo Vobis and other Church documents to illuminate the inter-dimensional relationships in personal formation. Finally, I tell a fictional story that illustrates how deficits in one domain of formation can negatively impact all the other dimensions of formation.  Check out the video on our Interior Integration for Catholics on YouTube at https://youtu.be/YDztbbNBBtk or on our IIC landing page at https://www.soulsandhearts.com/iic

A little background on the history of The Irvine Company.Read this entire episode here: http://tinyurl.com/55zadwbjIn 1864, James Irvine and three partners bought a 101,000-acre ranch, for around $26k. Much of that is now a city called Irvine, in California. It was initially a ranch focused on agriculture and it also encompassed coastal land. In the early 1900's they started developing some of the real estate, and in the 1950's they started large scale planned community development, also known as master planned communities, which encompasses building everything from residential to commercial and industrial buildings. The city of Irvine became one of the largest planned communities in the US.I recently read the book The Irvine Ranch: A Time For People by Martin A. Brower, and I will be sharing what I highlighted from the book below for my own knowledge.50'sNovices in such real estate transactions, The Irvine Company prepared lease and sale agreements which did not require development as proposed nor reversion of the land to the Company if not used by the lessee or purchaser.60'sAs they were expanding and continuously growing, one of their developments in the 60's pioneered the “zero lot line” concept, in which a house is placed on its neighbor's property line, resulting in one wide side yard rather than two small and useless side yards for each home. The unique plan placed groups of homes around a series of central green parks. Homes were priced from $27,000 to $32,000, a step below the prices in Turtle Rock Hills.As with all other Irvine Company village centers, included architecture consistent with its community, an attractive service station with pumps away from the streets, and with a supermarket and shops opening from a broad walkway rather than directly from the parking lot.Master planned to group buildings by size and use, the IIC was developed with strict covenants regulating land coverage, architectural design, landscaping and sound, odor and visual emissions. They were known for their innovative planning concepts.70'sThe Company's Residential Division had developed strict guidelines for each village which builders had to obey if they wanted to be invited to build homes on the Ranch. One of the homebuilders in Greentree — The Bren Company — was felt not to be cooperating. It was determined that Bren would never again be invited to build on the Irvine Ranch.When a citizen spokesman completed an attack one of of the Irvine company's plan for a new project and the city stood with him, the president at the time Raymond Watson, applauded. “You're not supposed to applaud,” chided Company director of public relations Martin Brower. “Sure I am, this is real democracy in action, with each of us respecting the other's role”.We will continue this exploration on the next post as I will highlight how Donald Bren became a partial owner of The Irvine Company and how he then became the sole owner of The Irvine Company.Subscribe to our newsletter here: www.montecarlorei.com

Check out our free downloads at nascentmc.com: Implementing AMA Style – 8 Things to Get Right in Your Next Project Needs Assessments – 7 Essentials for Getting Funded Working With Your Medical Writer – 8 Ways to Get the Most out of Them See the full write ups for today's episode at nascentmc.com/podcast  Here are the highlights: BIMZELX (bimekizumab) for Moderate-to-Severe Plaque Psoriasis: The FDA approved BIMZELX for treating moderate-to-severe plaque psoriasis, making it the first psoriasis treatment targeting interleukin 17A and interleukin 17F. The approval follows data from Phase 3 trials and comes after a prior delay due to COVID-related travel restrictions. Neoadjuvant Pembrolizumab for NSCLC: The FDA approved pembrolizumab for neoadjuvant and post-surgical adjuvant treatment in patients with resectable non-small cell lung cancer, adding to its indications in multiple tumor types. The approval was based on the phase 3 KEYNOTE-671 trial data. Adjuvant Nivolumab for Stage IIB/C Melanoma: The FDA granted approval to nivolumab for adjuvant treatment of melanoma in patients aged 12 and older with resected stage IIB or IIC disease, addressing the need to reduce the risk of recurrence. This is supported by the CheckMate76K trial data. Zilucoplan for Myasthenia Gravis: UCB Pharma's zilucoplan, a complement C5 inhibitor, received FDA approval for treating myasthenia gravis (MG), demonstrating rapid improvements in MG-specific efficacy outcomes based on the phase 3 RAISE study. IDP-126 (Cabtreo) First Triple-Combination Drug for Acne: Cabtreo, a triple combination topical gel for acne, received FDA approval as the first fixed-dosed, triple-combination treatment for patients aged 12 and older with acne vulgaris. Penbraya Meningococcal Vaccine in Adolescents: The FDA approved Penbraya, a vaccine covering the five most common serogroups causing meningococcal disease in adolescents, based on Phase 2 and Phase 3 trial data. It's administered as a two-dose series. Voxzogo in Dwarfism: Vosoritide (Voxzogo) was expanded for use in children under 5 with achondroplasia, the most common form of short-limbed dwarfism, after demonstrating safety and efficacy in this age group. QLOSI for blurry age-related near vision: The FDA approved QLOSI, a preservative-free eye solution, for the treatment of presbyopia, improving near visual acuity by pupil modulation and increasing depth of field. Maxigesic IV for Post-Op Pain: Maxigesic IV, a combination of paracetamol and ibuprofen, gained FDA approval for post-operative pain management, offering faster pain relief and reduced opioid usage. Xphozah for Chronic Kidney Disease: Tenapanor (Xphozah) was approved as an add-on therapy for patients with chronic kidney disease who can't tolerate or respond adequately to phosphate binders, based on phase 3 trial data, addressing high blood phosphorus levels. Zymfentra infliximab biosimilar for ulcerative colitis and Crohn's disease: Zymfentra, a subcutaneous infliximab biosimilar, received FDA approval for maintenance therapy in adults with moderately to severely active ulcerative colitis and Crohn's disease, based on LIBERTY-UC and LIBERTY-CD study findings.  Intro and outro music Garden Of Love by Pk jazz Collective    

ASCO: You're listening to a podcast from Cancer.Net. This cancer information website is produced by the American Society of Clinical Oncology, known as ASCO, the voice of the world's oncology professionals. The purpose of this podcast is to educate and to inform. This is not a substitute for professional medical care and is not intended for use in the diagnosis or treatment of individual conditions. Guests on this podcast express their own opinions, experience, and conclusions. Guests' statements on this podcast do not express the opinions of ASCO. The mention of any product, service, organization, activity, or therapy should not be construed as an ASCO endorsement. Cancer research discussed in this podcast is ongoing, so data described here may change as research progresses. The theme of the 2023 ASCO Annual Meeting was “Partnering With Patients: The Cornerstone of Cancer Care and Research.” From June 2 to 6 in Chicago, Illinois, and online, cancer researchers and clinicians from around the world gathered to discuss the latest cancer research and how to ensure that all people receive the cancer care they need. In the Research Round Up series, members of the Cancer.Net Editorial Board discuss the most exciting and practice-changing research in their field presented at the meeting and explain what it means for people with cancer. In today's episode, our guests will discuss new research in melanoma and health equity. First, Dr. Katy Tsai discusses new research in melanoma. Dr. Tsai is a medical oncologist and Assistant Professor of Medicine in the Division of Hematology and Oncology at the University of California, San Francisco. She is also the 2023 Cancer.Net Associate Editor for Melanoma & Skin Cancer. You can view Dr. Tsai's disclosures at Cancer.Net. Dr. Tsai: Hello. Welcome to the ASCO Cancer.Net Research Round Up. I'm Katy Tsai, an associate professor of medicine and the clinical medical director of the Melanoma and Skin Cancer Program at the University of California, San Francisco. I'm happy to be here today to discuss research on melanoma and skin cancers presented at the 2023 ASCO Annual Meeting. I do not have any disclosures relevant to the studies to be discussed. So, it's always exciting to see the latest research presented at ASCO. One theme in particular that I'd like to highlight in this podcast is recent advances in the field of adjuvant therapy. For the listeners who may not be familiar with this terminology, adjuvant therapy refers to drugs given after surgery to try to decrease the risk of cancer recurrence. Specifically, late-breaking abstract 9505 presented updates from KEYNOTE-716, an adjuvant study of pembrolizumab, or pembro, in patients with resected high-risk stage II melanoma. Late-breaking abstract 9503, which I'll also discuss, presented data from KEYNOTE-942, a pivotal study of a personalized cancer vaccine plus pembrolizumab in patients with resected high-risk stage III and stage IV melanoma. So, let's start with KEYNOTE-716. We've known for some time in our field now that adjuvant pembrolizumab or nivolumab can help decrease the risk of recurrence for patients with resected stage III or IV melanoma. What may not be as well-known, however, is that patients with stage IIB or IIC melanomas, in other words, thicker, ulcerated primary melanomas, even without lymph node spread, actually have a comparable risk of melanoma recurrence compared to patients with early stage III melanomas. KEYNOTE-716 was a large, international phase 3 study that randomized patients with stages IIB and C melanoma to receive either pembro or placebo. The positive results showing improvement in relapse-free survival led to approval of adjuvant pembro in December 2021, but what was presented at ASCO was an update on distant metastasis-free survival. This is obviously an important endpoint for us because ultimately, if someone is going to develop widely metastatic disease, unfortunately, it is a development of these distant metastases that we are concerned about. So what we saw here is that with landmark 36-month follow-up, there was a 41% reduction in the risk of developing distant metastasis in patients who were treated with pembro compared to those who received the placebo. In addition, there was a consistent maintained benefit in relapse-free survival, and importantly, no changes in the side effect profile. These are important data because I believe it is practice-changing in the sense that this is a population of patients who historically might not ever have been referred to medical oncology, maybe just monitored serially with their dermatologists. And this is an option that should be discussed. Ultimately, the risk versus benefit about whether to pursue a year of therapy versus maybe consider treatment only at the time of recurrence is a very personalized discussion between a patient and their treating oncologist, but it is an option that should definitely be offered. So let's move on to KEYNOTE-942. The novel drug being tested in this trial is very exciting. We're calling it “individualized neoantigen therapy.” So this is basically a platform that allows us to develop individualized treatment for someone based on characteristics of their own cancer. This involves taking the actual tumor specimen, genomic sequencing, specifically whole-exome sequencing is performed to try to identify any changes in the DNA. And then through a bioinformatic pipeline, the mutations in the DNA that are thought to be most likely to generate proteins that can be bound within presenting molecules are then identified in the computer program, then synthesized within mRNA. So very similar to the way that COVID vaccines have been made. So this actually becomes the actual drug product. So in this study, patients were randomized to receive either pembrolizumab by itself for a year, which is, as we alluded to earlier, standard adjuvant therapy, but then with the addition of this individualized neoantigen therapy starting with dose 3 and then throughout the rest of the year. So the recurrence-free survival data were actually presented earlier this year at another major conference, AACR [American Association for Cancer Research], and were highly positive. At ASCO 2023, I think what was most impressive about the presented data is that distant metastasis-free survival, so again, a similar important endpoint that we discussed with the other trial, is that the distant metastasis-free survival here was quite impressively maintained. There was a hazard ratio of .35, meaning really a 65% reduction in the risk of recurrence for patients who received the personalized neoantigen therapy plus pembrolizumab. So this is a huge advantage for distant metastasis-free survival in this particular population of patients. What was even more intriguing is that usually when we combine therapies, we tend to see additive toxicity, more side effects. And what was really exciting about this particular trial is that the additive toxicity really wasn't as much as you would expect for giving 2 immunotherapies at the same time. I'll also highlight that even though these results are really exciting within melanoma, that part of the reason this data is so exciting is that it represents a really promising platform for therapeutic development and application in other tumors besides melanoma. So this is definitely super exciting. While perhaps not practice-changing in this moment, it's potentially practice-changing. And I look forward to seeing additional data coming in from planned trials using this particular combination in the metastatic setting in addition to the adjuvant setting. So on the whole, I do think that updates in adjuvant therapy for melanoma were super exciting to see at ASCO 2023. As I mentioned earlier, it's a very large conference. A lot of exciting data being presented. So I do think that other themes to pay attention to as we continue to sort through existing data and look forward to incoming data from forthcoming trials is looking at neoadjuvant therapy. For example, drug given before surgery to try to improve long-term outcomes. For example, at ASCO this year, there was interesting neoadjuvant immunotherapy data presented not for melanoma, but for a different type of skin cancer called squamous cell carcinoma. So that would definitely be another theme to pay attention to in the coming months and years. Thinking about novel combinations, for example, what's new in immune checkpoint inhibitors, we've been used to for a long time referring only to anti-PD1 antibodies, anti-CTLA4 antibodies. What was interesting to see this year were updates in novel combinations, for example, PD1 antibodies combined with LAG3 antibodies. Antibodies against TIGIT. So I think this will be another exciting space to pay attention to both in the metastatic skin cancer setting and in the adjuvant and neoadjuvant settings. Thank you for your time and attention. That concludes my research roundup for melanoma and skin cancers. Thank you. ASCO: Thank you, Dr. Tsai. Next, Dr. Manali Patel discusses new research in health equity. Dr. Patel is a medical oncologist and Assistant Professor of Medicine at Stanford University. She is also the 2023 Cancer.Net Associate Editor for Health Equity. You can view Dr. Patel's disclosures at Cancer.Net. Dr. Patel: Hi, my name is Manali Patel. I'm the Associate Editor for Health Equity for Cancer.Net, and I'm so incredibly excited to present some really amazing work that was presented at our ASCO Annual Meeting this past June in Chicago. Before I start, I do have one disclosure. I will be talking about studies that were presented relating to patient navigation and one study in particular that my group presented looking at community health workers. And so that is a little bit of a disclosure that I would like to address upfront. And now, just to get right started. I thought what was really interesting was the amount of work this year that was presented on disparities in health equity. As in past years, we actually saw quite an influx, probably more so this year than previously, on studies that looked at differing outcomes, inequities in cancer care delivery, describing disparities in terms of receipt of treatment, so if people were receiving treatment. There tended to be a lot of studies that focused on looking at and describing a lot of these disparities. But what I was really impressed by came out from the pediatric colleagues, individuals who are taking care of younger patients, children who are less than the age of 18, and how many of those particular studies were focused on moving from description to actually intervening and making a difference in health equity. And so I want to highlight a couple. There was one that was done out of Dana-Farber, and actually, a multi-site group of authors. So lots of authors from all over the place, but Emily Jones was the lead author. And they described and actually evaluated how they could collect, in the context of clinical trials for children, which is called Children's Oncology Group Trial-- how they could collect social determinants of health data, meaning data that evaluates people's income, transportation, where people live, what kind of work they may do, if they have food and housing insecurity. And what they were able to show is that, by embedding a lot of these data points-- they actually made these data points optional for patients when they came into the clinical trial. And they found high feasibility, meaning lots of people that were signing up to do clinical trials for the Children's Oncology Group Trial were able to complete this extra data, which is extremely important and is a remarkable willingness of individuals to participate in providing this data which is important for their treatment. Along those same lines, Amy Newman from the Children's Hospital of Philadelphia really did a very nice study looking at the feasibility of what they called PediCARE. And it was this intervention that was focused on trying to ensure that people-- again, children less than the age of 18 across 2 different clinics. They evaluated whether PediCARE would help people to receive necessary and important resources as it relates to social and economic needs. And so they screened for food insecurity, for housing insecurity, for people that had difficulties paying for utilities, and transportation security. And then they randomized individuals to either PediCARE or to just usual cancer care. And what they found was that 100% of the people that were randomized to PediCARE successfully received grocery and transportation resources. They felt that it was easier to buy food for their family, and they reported it was easier to get to and from the hospital and that they would be very likely to report and to recommend this intervention to other individuals. And so it really shows how these interventions can move from just describing that housing, food insecurity or problems-- number 1, it starts with the collection of the data, right? What's really important is making sure that we collect this data because we don't currently do that in cancer care. And then number 2, when we actually do collect the data, what are we going to do about it? And it shows that these interventions really do help people to move past their housing and social and economic issues that they may experience into actually receiving care that's important and necessary to improve outcomes. We did see a lot of data reflecting the importance of health insurance and big policies, what I call Big P, which are these national policies, like the Affordable Care Act. And now we've seen, just year after year and including this year, plethora of studies showing how beneficial the Affordable Care Act has been on reducing disparities and improving cancer outcomes overall. We also saw other studies, such as one presented by Dr. Gladys Rodriguez from Northwestern, which looked at disparities in the intensity of care at the end of life amongst patients with gastrointestinal cancers. And the team revealed, across almost 20 years of data in California, that patients were receiving higher rates of what would be considered low-quality care. Now, this is lower hospice use, which we know helps to actually improve survival, lower rates of palliative care use, and greater rates of burdensome hospitalizations. And now, why I think this is particularly important is because this study evaluated what we know is a problem, that there is low-quality care amongst patients from particular racial and ethnic populations, such as Black and Hispanic patient populations, that aren't receiving the right care when they're diagnosed. And then what this reveals is that, even at the end of life, they're perhaps still receiving low-quality care. Another study looked at screening, which I thought was really impressive. It was by Nicole Anne Gay from the UM Sylvester Comprehensive Cancer Center in Miami. And what they evaluated was essentially a quality improvement program to reduce disparities in lung cancer screening. As a lung cancer doctor myself, it's still shocking that fewer than 6% of people that should receive lung cancer screening, meaning a screening test to help us identify and to treat patients with lung cancer-- they aren't receiving lung cancer screening. And so we know that this is a problem overall. They put into place what's called a multi-level, meaning that there were improvements in the electronic health record that they embedded. They also provided patients with navigation, and they also helped clinicians in the primary care clinics obtain information about who should be eligible and which patients should be receiving screening. And what they found was that they were able to move screening rates from 25% improvement completed during the project period from their baseline, which is actually quite impressive. We also saw an interesting study, and actually, just an interesting evaluation, of childhood leukemia survival on the U.S.-Mexico border. And it was a description of how to implement changes by strengthening care partnerships. And so they evaluated and they described the implementation of this program to achieve what they called sustainable high-quality care for children with leukemia. It was done by Paula Aristizabal and was really in a unique border health setting. It was in partnership between the North American and Mexican institutions. And they used what was called the strengthening model developed by the World Health Organization to evaluate specific domains and to try to improve a sustainable program for children with acute lymphoblastic leukemia at a public referral hospital right on the border region. And I thought that that study was particularly interesting because it shows how to be able to use an approach to improve the staffing of a leukemia service, to implement a sustainable training program as well for other clinicians to learn how to provide leukemia care, and then also to try to improve clinical outcomes and funding for patients to receive medications through local partnerships. I thought it was a really fantastic description of how to begin to do this work that is extremely necessary in low- and middle-income nations but also even on our own U.S.-Mexico border. There were also a lot of studies that evaluated the importance of social and economic factors. We know that financial toxicity, which is an unfortunate side effect of cancer treatment and cancer care and a cancer diagnosis overall, is associated with worse outcomes. Financial toxicity means the burdens and costs that arise with having a cancer diagnosis. And now we've seen studies that were presented at ASCO this past year by Dr. Khan, who showed that, within 2 years of diagnosis, are at higher risk for dying after adjusting for many social and also clinical factors. And Dr. Hu also presented data looking at the implications of having a lot of medical debt and death. And what both of these studies showed is that medical debt is associated with having perhaps a lower likelihood of surviving. It does make sense for Dr. Hu's study that one would have a lot of medical debt if they also have a lot of other conditions, but it does begin to shed some light on the fact that there are worse clinical outcomes, meaning people aren't doing as well, depending on how much other medical care expenses they may have. And then finally, one important piece, which I think is really crucial for what's happening now in the way that oncologists may perhaps be able to advocate for payment for services that are important, is looking at navigation studies. Now, this is patient navigators, and that is a very broad topic. And so there were lots and lots of studies that came out at ASCO that evaluated the importance of navigation, including our own work that looked at what happens to veterans after receiving a lay health worker or a navigator to assist with advanced care planning, meaning helping veterans to understand their goals and preferences. And what these studies have shown is that there's actually not only clinical benefit but also, in our own study, that perhaps there may be a survival benefit even 10 years later. It was very wonderful to be at ASCO this past year, and I really hope that you all can look at some of these studies or take away the important and amazing work that's going on in the health equity space. And I thank you for listening to our podcast. ASCO: Thank you, Dr. Patel. You can find more research from recent scientific meetings at www.cancer.net. Cancer.Net Podcasts feature trusted, timely, and compassionate information for people with cancer, survivors, and their families and loved ones. Subscribe wherever you listen to podcasts for expert information and tips on coping with cancer, recaps of the latest research advances, and thoughtful discussions on cancer care. And check out other ASCO Podcasts to hear the latest interviews and insights from thought leaders, innovators, experts, and pioneers in oncology. Cancer.Net is supported by Conquer Cancer, the ASCO Foundation, which funds lifesaving research for every type of cancer, helping people with cancer everywhere. To help fund Cancer.Net and programs like it, donate at CONQUER.ORG/Donate. [music]

Dr. Michael Atkins and Dr. Vernon Sondak highlight the latest updates to the systemic therapy for melanoma recommendations in this newest guideline. The discussion covers neoadjuvant and adjuvant therapy for resected cutaneous melanoma, options for unresectable and/or metastatic cutaneous melanoma, and therapies for noncutaneous melanoma. They review the importance of this guideline and the most pressing outstanding questions to help inform better treatment strategies for patients with melanoma. Read the full guideline update, "Systemic Therapy for Melanoma: ASCO Guideline Update" at www.asco.org/melanoma-guidelines. TRANSCRIPT This guideline, clinical tools, and resources are available at http://www.asco.org/melanoma-guidelines. Read the full text of the guideline and review authors' disclosures of potential conflicts of interest disclosures in the Journal of Clinical Oncology, https://ascopubs.org/doi/10.1200/JCO. 23.01136 Brittany Harvey: Hello and welcome to the ASCO Guidelines podcast, one of ASCO's podcasts delivering timely information to keep you up to date on the latest changes, challenges, and advances in oncology. You can find all the shows, including this one at asco.org/podcasts. My name is Brittany Harvey, and today I'm interviewing Dr. Michael Atkins from Georgetown Lombardi Comprehensive Cancer Center, and Dr. Vernon Sondak from H. Lee Moffitt Cancer Center and Research Institute, authors on “Systemic Therapy for Melanoma: ASCO Guideline Update.”   Thank you for being here today, Dr. Atkins and Dr. Sondak. Dr. Vernon Sondak: Happy to be here. Dr. Michael Atkins: Yeah, it's a pleasure. Brittany Harvey: Great. Then before we discuss this guideline, I'd like to note that ASCO takes great care in the development of its guidelines and ensuring that the ASCO conflict of interest policy is followed for each guideline. The disclosures of potential conflicts of interest for the guideline panel, including Dr. Sondak and Dr. Atkins, who have joined us here today, are available online with the publication of the guideline in the Journal of Clinical Oncology, which is linked in the show notes. So then, to dive into the content here, Dr. Sondak, what prompted this full update to the Systemic Therapy for Melanoma Guideline, which was initially published in 2018? Dr. Vernon Sondak: Well, the last 10 years or so have seen enormous advances in the management of metastatic melanoma and localized melanoma with systemic therapy, and the last few years haven't slowed up at all. So since 2018, we've seen new approvals, we've seen key pivotal trials that have shown some amazing results that we'll talk about, and all of these things together weighed into the decision to update the systemic therapy guidelines. Brittany Harvey: Great. Thank you for that background on what prompted the update. So then, this guideline provides updated recommendations across four clinical questions. I'd like to review the key updated recommendations for our listeners. So first, Dr. Sondak, what has changed in the updated recommendations regarding neoadjuvant therapy for adults with resectable cutaneous melanoma? Dr. Vernon Sondak: Neoadjuvant therapy is one of the most rapidly evolving and exciting parts of the management of melanoma with systemic therapy. The updated guidelines now include neoadjuvant pembrolizumab as a new recommendation for patients with resectable stage IIIB to IV cutaneous melanoma. This is based on the SWOG S1801 clinical trial, which was a very simple and yet incredibly influential clinical trial. It took patients with resectable metastatic melanoma, either metastatic to the lymph nodes or beyond, as long as it could be removed surgically, and randomized all of the patients to either get surgery, followed by a year of adjuvant pembrolizumab, which is very standard, or the same exact surgery and the same total amount of pembrolizumab, but with three of the doses given before surgery. So that simplicity, that ability to just compare the effect of neoadjuvant or preoperative pembrolizumab to entirely postoperative adjuvant pembrolizumab, made this trial a really pure assessment of the value of neoadjuvant pembrolizumab.  Impressively, this study showed a significant improvement in event-free survival for patients who got those three doses of pembrolizumab upfront. What's event-free survival? That includes relapse-free survival, but also the kinds of events that you can see happening with neoadjuvant therapy, such as progression of the disease prior to surgery that makes the patient unresectable. And the bottom line is that there was really the same number of issues with neoadjuvant pembrolizumab as with surgery, followed by adjuvant therapy, but there were many fewer recurrences among the patients who got neoadjuvant pembrolizumab. So that's why this was put into the guidelines. Brittany Harvey: Excellent. I appreciate you reviewing the evidence behind those recommendations and what's new for neoadjuvant therapy. So then, Dr. Atkins, moving into adjuvant therapy, for patients with resected cutaneous melanoma, what is new in the recommendations regarding adjuvant systemic therapy options? Dr. Michael Atkins: Sure. In the prior version, adjuvant therapy was recommended for patients with stage IIIB, IIIC, and for some patients with stage IV resected to NED. And those were based on studies with adjuvant pembrolizumab, adjuvant ipilimumab, and adjuvant nivolumab compared to ipilimumab. But what's happened since then is some really important adjuvant studies have been carried out in patients with stage IIB, IIC, and IIIA disease who are at slightly lower risk of recurrence, but still have substantial risk of recurrence, and make up a large percentage of the patients who eventually develop stage IV disease. And in these studies, one with pembrolizumab compared to placebo, there was about a 40% to 50% reduction in relapse-free survival observed, leading to the FDA approval of pembrolizumab in that setting. And then recently we saw the results of a similar study involving nivolumab that showed maybe even a slightly better reduction in the risk of relapse in that same patient population. Ultimately, this will lead to FDA approval as well. And we felt it was important to put in the guidelines the results of these studies so that people can have informed discussions with their patients about whether they want to receive this therapy going forward. It's important to point out that we don't have good data yet on overall survival. We just have data on relapse-free survival. So we don't, for sure, know that treating patients early, rather than waiting until a subset of them relapse and treating those late leads to an improved overall survival. That's an important discussion to have with patients to provide them with this option. In addition, we saw the results of the IMMUNED trial, which looked at nivo-ipi or nivo monotherapy versus placebo or observation in patients with stage IV disease that had been completely resected. And we saw dramatic improvement for the nivo-ipi combination compared to nivo or observation in those patients with stage IV NED. And we felt that, therefore, this was also an important patient population where we should offer guidance Brittany Harvey: Absolutely. That shared patient-clinician decision-making is paramount. And then you've both reviewed the options for resected cutaneous melanoma. But Dr. Atkins, what is new regarding systemic therapy options for patients with unresectable and/or metastatic cutaneous melanoma? Dr. Michael Atkins: Yes. For patients with unresectable metastatic cutaneous melanoma, there was a new drug combination that was approved combining nivolumab with relatlimab, which is an anti-lag-3 antibody that showed benefit compared to nivolumab monotherapy across almost all subgroups. In particular, the benefit was similar regardless of BRAF mutation status, regardless of elevated LDH, and regardless of patient stage. That led to FDA approval, and this is now an available treatment option, which is associated with less toxicity and similar efficacy to the standard of care nivo-ipi. In addition, although nivolumab-ipilimumab had been approved and was in our last recommendation for patients with BRAF-mutated melanoma, we didn't really know whether they should receive BRAF/MEK inhibitors, which were also approved, versus nivolumab-ipilimumab as their initial therapy. And so in the past few years, we saw the results of the DREAMseq trial, which randomized patients with BRAF-mutant melanoma to either nivolumab-ipilimumab, followed by BRAF-MEK inhibitor progression, versus the converse sequence. And we saw that at two years, the starting with a nivolumab-ipilimumab had a 20% improvement in two-year overall survival. This prompted the NCCN to change their guidelines to list nivolumab-ipilimumab or other immunotherapies as a preferred frontline therapy. And we thought that this data was important enough and somewhat validated by a randomized phase II trial, the SECOMBIT, which had a lot smaller numbers to encourage us to change the guidelines. Other minor things that we did were to take T-VEC and no longer recommend that as an option for patients with BRAF-wild type disease who had progressed on anti-PD-1 therapy and that ipilimumab and ipilimumab-containing regimens were no longer recommended for patients with BRAF-mutated disease after progression on other immunotherapy. We felt that those patients probably are best served to get BRAF/MEK inhibitors. Brittany Harvey: It's good to have clarity on some of those sequencing options for patients and also on which treatments are working better for patients in these subpopulations. So then, Dr. Sondak, the last set of recommendations. What has changed regarding options available for patients with noncutaneous melanoma?  Dr. Vernon Sondak: There's no question that our patients with noncutaneous melanomas, such as uveal melanoma or mucosal melanoma, have many fewer options and haven't benefited as much from the revolution in treatment that we've seen with our cutaneous melanoma patients, but there have been definite improvements and progress. The full update incorporates new recommendations for uveal melanoma that were published in 2022 as a rapid recommendation update, specifically a new drug called tebentafusp, which is restricted to HLA-A*02:01-positive patients. It's HLA-type restricted, but it is active in patients with metastatic uveal melanoma. And so the new guideline is that previously untreated patients with metastatic uveal melanoma who are HLA-A*02:01-positive should be offered tebentafusp as a treatment option. So that means all our patients with metastatic uveal melanoma should get HLA typed, so they know if they're a person who is eligible for this treatment and it should be considered early on in the treatment paradigm. Brittany Harvey: Well, thank you both for reviewing the updates to these evidence-based recommendations. There's a lot that's new in this field.  So then, Dr. Atkins, what is the importance of this guideline? And in your view, how will it impact clinicians, and also how will these guideline recommendations affect patients? Dr. Michael Atkins: Sure. Well, we have new treatments such as relatlimab and tebentafusp that are available and should be offered to appropriate patients, and new data on how to optimally apply previously approved treatments such as nivolumab-ipilimumab in patients with BRAF-mutated or resected stage IV melanoma, pembrolizumab use in the neoadjuvant setting, and nivo and pembro in earlier stage disease. And with this new information out there and included in the guidelines, hopefully, this will allow practitioners to give the best possible treatments to their patients, and patients to receive treatments which will improve their outcomes. Brittany Harvey: Absolutely. It's great to have new data to better inform treatment options for patients with melanoma.   So then, finally, Dr. Sondak, what are some of the most pressing outstanding questions regarding systemic therapy for patients with melanoma that may need to be addressed in a future guideline update? Dr. Vernon Sondak: Every advance brings up new questions. In neoadjuvant therapy, we have single-agent pembrolizumab with strong data from the randomized trial I spoke about. We anticipate more data about combination immunotherapy, specifically low-dose ipilimumab and nivolumab in the setting of neoadjuvant therapy. There are some trials going on with that. The best neoadjuvant treatment, the best sequence, how long should we treat, and even should we change the surgery based on the results of neoadjuvant therapy, not just the surgery, but the postoperative adjuvant therapy? Those are all questions that are key in the neoadjuvant side.  In the adjuvant therapy side, we have much more clarity now about BRAF versus immunotherapy in unresectable disease, but we still don't know always what's the best adjuvant therapy for our BRAF-mutated patients. That's an area we hope will eventually get more clarity, but I think it's going to take a while for that.   And finally, we'll learn more about the optimum sequencing of patients with metastatic disease, but especially for the patients who've already failed adjuvant or neoadjuvant therapy. So much of the data that Dr. Atkins and I talked about in metastatic disease, whether cutaneous or noncutaneous, involved previously untreated patients. But so many of our metastatic disease patients today have come to us already with some form of treatment in the adjuvant or neoadjuvant setting. We still have a lot of work to do to define the best treatment strategies for those patients.  Brittany Harvey: Definitely. Well, we'll look forward to learning more as new data comes out and as some of that research comes to fruition. So I want to thank you so much for your work to update this guideline and thank you for your time today, Dr. Sondak and Dr. Atkins. Dr. Vernon Sondak: Thank you. Dr. Michael Atkins: You're very welcome. Thanks a lot. Brittany Harvey: And thank you to all of our listeners for tuning in to the ASCO Guidelines podcast. To read the full guideline, go to www.asco.org/melanoma-guidelines. You can also find many of our guidelines and interactive resources in the free ASCO Guidelines app available in the Apple App Store or the Google Play Store. If you have enjoyed what you've heard today, please rate and review the podcast and be sure to subscribe so you never miss an episode. The purpose of this podcast is to educate and to inform. This is not a substitute for professional medical care and is not intended for use in the diagnosis or treatment of individual conditions.   Guests on this podcast express their own opinions, experience, and conclusions. Guest statements on the podcast do not express the opinions of ASCO. The mention of any product, service, organization, activity, or therapy should not be construed as an ASCO endorsement.    

Welcome to Episode 124 Sponsored by CultTVMan, Sean's Custom Model Tools and Return To Kit FormHostsStuartGeoffAnthonyKrisTerryThanks to our latest Patreon and Buy Me a Coffee Supporters:***************************************LATEST NEWSIPMS USA announces “No Touch” policy for models at contests.SPECIAL CONTEST Winner - Congratulations Preston Culp! Look out for an email from us to set up your IPMS USA Membership! Thank you to the IPMS USA Executive for their generous participation!Legacy Presents from R2KF! Brett has streamlined his business to focus on his amazing Valkyrie Canopy Masks! They are the best - check them out here! However, look for a Huge Resin Macross kit coming soon!***************************************MAILBAGWe want to hear from you! Let us know if you have any comments or suggestions scalemodelpodcast@gmail.com. ***************************************LATEST HOBBY ANNOUNCEMENTSSix new 1/48th scale aircraft detail sets from Mini Craft CollectionMiniArt P-47D in 1/48Tamiya Sept Announcements3D-Wild announcing USS Midway in 1/350Some comments from 3D-Wild on a competitor doing the same kit.Xtradecal releasing sets for Airfix's 1:48 scale Westland Sea KingQuickboost August Resin ReleasesFantastic Plastic is working on a 1:72 SR-72 Darkstar hypersonic testbed.Border Model is to release a 1/35th Supermarine Spitfire Mk.Vb kitSpecial Hobby Newsletter AugustGundam News - New Real Type MG 1/100 Freedom & Justice GundamAFV has upgrade items for your 1/16 scale SdKfz. 251 kit from Das Werk. What's new at Scalemates.com***************************************SPONSOR AD #1Cult TV Man***************************************InterviewKris Sieber (Luftraum72)https://luftraum72.com/product/super-detailing-the-f-14-tomcat/[foogallery id="3404"]***************************************WHAT'S ON THE BENCHStuart - Not much progress this week, work is taking up much of my time and the summer heat zaps the mojo. I did pick up the Arma Hobby 1/48 Hurricane Mk. IIc and it's a very nice kit at first look.Geoff - Got the first colours on the Savoia Marchetti, but otherwise, it was all about getting the house spiffy for a wedding group. Now that that's done, we can maybe relax…Terry - Cleaning the bench a little at a time. I discard some clutter each time and have found things I knew I had somewhere. Doing a little resin kit cleanup, too - including the Elric White Wolf figure which needs more cleanup than thought. Pups are getting bigger - Toshi is 37lbs now. Including Toshi and Zeus' attempt at a New Wave album cover.[foogallery id="3418"]Kris - Boxes, mailing labels, and books, books, books! Arma Hobby 1/72 F-6C Mustang for next book Mini Hangar No.1 published by Joycraft. Secret project which I can't go into details on at the moment.Anthony - Priming the Gundam Hazel and working on some finer detail painting for the GP03. Just killing it when it comes to procrastinating on painting figures for my Bosnia MIFV build!*************************************** WHAT WE'RE READINGStuart - Starry Messenger: Cosmic Perspectives on Civilization - Just started last night. In a time when our political and cultural views feel more polarized than ever, Tyson provides a much-needed antidote to so much of what divides us, while making a passionate case for the twin chariots of enlightenment―a cosmic perspective and the rationality of science.Geoff - “Maximum Bob” by Elmore Leonard. A quick fun summer read I hope!Kris - Nothing modelling-related, just Sci-fi from Adrian TchaikovskyTerry - Almost done with Tom Cleaver's Clean Sweep, started Moorecock's Elric books.Anthony - Nuttin' much, just finished Simu Liu's autobiography, “We Were Dreamers”. Covering my eyes until I get my copy of Kris' F-14 book so as to not ruin the surprise!***************************************SPONSOR AD #2Seans Custom Model Tools***************************************THINGS WE'VE SEENNeil Prentice doing a digital camouflage scheme on a VF-11 ThunderboltNeil's Tomcat and that little dropship. The Tomcat has a VF-0 gun pod on its centerline, but you can't see it[foogallery id="3407"] ***************************************THE LAST WORDSMP Ep. 124 is also sponsored by Return To Kit Form (R2KF). Check out their web store!For more modelling podcast goodness, check out other modelling podcasts at modelpodcasts.comPlease leave us a positive review if you enjoy what we're doing!Check us out: FaceBook, YouTube, and our very own websiteWe also have merchandise now. Check it out on Redbubble 

Called ‘Restoring Stepwells, Reviving Life', an IIC exhibition, which opened on 22 July and closes today, shows how eight step wells – two in Delhi, six in Hyderabad – were painstakingly resuscitated.

CME credits: 0.25 Valid until: 09-06-2024 Claim your CME credit at https://reachmd.com/programs/cme/preventing-disease-recurrence-adjuvant-therapy-stage-iibiic-melanoma/15392/ The 5-year recurrence rates for stage IIB and IIC melanoma are up to 46%, but now new immunotherapy options are FDA-approved for the adjuvant treatment of stage IIB and IIC melanoma. Find out why this matters and hear Drs. Jason Luke and Tara Mitchell break down the latest data on treating stage IIB and IIC melanoma with adjuvant immunotherapy.=

Host: Jason J. Luke, MD, FACP Guest: Tara Mitchell, MD The 5-year recurrence rates for stage IIB and IIC melanoma are up to 46%, but now new immunotherapy options are FDA-approved for the adjuvant treatment of stage IIB and IIC melanoma. Find out why this matters and hear Drs. Jason Luke and Tara Mitchell break down the latest data on treating stage IIB and IIC melanoma with adjuvant immunotherapy.

Track Listing:1 Nielsen: Symphony No. 1 in G Minor, Op. 7: / I. Allegro orgoglioso 09:202 II. Andante 07:473 III. Allegro comodo 07:494 IV. Allegro con fuoco 08:58 5 Symphony No. 2, Op. 16 The Four Temperaments / I. Allegro collerico 10:066 II. Allegro comodo e flemmatico 04:567 III. Andante malincolico 12:568 IV. Allegro sanguineo 07:02 9 Symphony No. 3, Op. 27 Espansiva / I. Allegro espansivo 11:0910 II. Andante pastorale 10:3811 III. Allegretto un poco 06:4312 IV. Finale. Allegro 10:52 13 Symphony No. 4, Op. 29 The Inextinguishable / I. Allegro 12:2114 II. Poco allegretto 04:3215 III. Poco adagio quasi andante 10:4716 IV. Allegro 08:51 17 Symphony No. 5, Op. 50: Ia. Tempo giusto 10:2918 Ib. Adagio 08:5219 IIa. Allegro 06:1420 IIb. Presto 02:5821 IIc. Andante poco tranquillo 04:2022 IId. Allegro 02:5623 Symphony No. 6 Sinfonia Semplice / I. Tempo giusto 14:2724 II. Humoreske 04:1125 III. Proposta seria 05:2726 IVa. Allegro – Tema. Allegretto un poco 00:5827 IVb. Var. 1 00:3228 IVc. Var. 2. Allegretto quasi andantino 00:2829 IVd. Var. 3. Più vivo – Var. 4. – Var. 5. Brioso 02:1730 IVe. Var. 6. Tempo di Valse – Var. 7 02:1131 IVf. Var. 8. Molto adagio 03:0232 IVg. Var. 9. Tempo di tema 00:2833 IVh. Fanfare 01:44Help support our show by purchasing this album  at:Downloads (classicalmusicdiscoveries.store) Classical Music Discoveries is sponsored by Uber and Apple Classical. @CMDHedgecock#ClassicalMusicDiscoveries #KeepClassicalMusicAlive#CMDGrandOperaCompanyofVenice #CMDParisPhilharmonicinOrléans#CMDGermanOperaCompanyofBerlin#CMDGrandOperaCompanyofBarcelonaSpain#ClassicalMusicLivesOn#Uber#AppleClassical Please consider supporting our show, thank you!Donate (classicalmusicdiscoveries.store) staff@classicalmusicdiscoveries.com This album is broadcasted with the permission of Crossover Media Music Promotion (Zachary Swanson and Amanda Bloom).

1990 USA Hubble Space Telescopehttp://news.bbc.co.uk/onthisday/hi/dates/stories/april/24/newsid_4098000/4098760.stm 1916 Ireland Easter Uprisinghttps://www.history.com/topics/british-history/easter-rising 1984 USA Apple IIchttps://applemuseum.bott.org/sections/computers/IIc.html Support the show

Over the last few years, a wide range of stakeholders across the world have developed a new approach to governance mechanisms and public service delivery. This new model is centred around the concept of digital public goods - open-source digital solutions - that adhere to minimum privacy criteria and user security and do no harm by design. This episode of All Things Policy features IIC fellows (University of Chicago Trust), Ritul Gaur and Arjun Gargeyas, who are joined by Liv Nordhaug (Co-Lead at Digital Public Goods Alliance) to discuss the concept of digital public goods, the challenges and opportunities they present, and how they can be used to benefit society at scale.  You can follow Liv Nordhaug on Twitter: https://twitter.com/livmarte  You can follow Ritul Gaur on Twitter: https://twitter.com/GaurRitul  Check out Takshashila's courses: https://school.takshashila.org.in/ Do follow IVM Podcasts on social media. We are @IVMPodcasts on Facebook, Twitter, & Instagram. https://twitter.com/IVMPodcasts https://www.instagram.com/ivmpodcasts/?hl=en https://www.facebook.com/ivmpodcasts/ You can check out our website at https://shows.ivmpodcasts.com/featured Follow the show across platforms: Spotify, Google Podcasts, Apple Podcasts, JioSaavn, Gaana, Amazon Music Do share the word with your folks!See omnystudio.com/listener for privacy information.

Summary  In this episode, Dr. Peter reviews the limitations of current Catholic resources on anger, and then reviews secular resources, including interpersonal neurobiology and the structural theory of dissociation.  We examine the role of the body in anger responses, and discuss more wholistic ways of working constructive with parts that experience anger, rather than trying to dismiss anger, suppress it or distract from it.   Lead-in William Blake, A Poison Tree: I was angry with my friends; I told my wrath, my wrath did end. I was angry with my foe: I told it not, my wrath did grow.  We've all experienced anger and we've all experienced angry people  We know it's a problem.  And global data suggest that it's getting worse.   Gallup world poll from 2021: 140 countries  Did you experience the following feelings during a lot of the day yesterday? How about anger?  17% of US respondents agreed 26% of women worldwide up from 20% from 10 years ago  20% of men -- flat from 10 years ago.   Harm can come from anger Mark Twain “Anger is an acid that can do more harm to the vessel in which it is stored than to anything on which it is poured.”  CCC 2302  By recalling the commandment, "You shall not kill," our Lord asked for peace of heart and denounced murderous anger and hatred as immoral. Anger is a desire for revenge. "To desire vengeance in order to do evil to someone who should be punished is illicit," but it is praiseworthy to impose restitution "to correct vices and maintain justice." If anger reaches the point of a deliberate desire to kill or seriously wound a neighbor, it is gravely against charity; it is a mortal sin. The Lord says, "Everyone who is angry with his brother shall be liable to judgment."   "Everyone who is angry with his brother shall be liable to judgment."  And who hasn't been angry -- including Jesus himself?.  We have got to unpack this There is so much misunderstanding about anger in the Catholic world, so much of the way that Catholics have approached anger has been limited, misinformed, and misguided When I think about why the Catholic Church in the US, in Canada, in Europe and Australia, in the entire Western World, there are many factors.   Brandon Vogt  New Stats on Why Young People Leave the Church  based on his book Return:  How to Draw Your Child Back to the Church One critical factor is that cradle Catholics, especially young Catholics do not believe that the Church can help them with their problems.  Diocese of Springfield Exit Surveys (2014)  68% – Spiritual needs not met67% – Lost interest over time Only 7% of Millennials raised Catholic still actively practice their faith today (weekly Mass, pray a few times each week, say their faith is “extremely” or “very” important) 6.5 people leave the Catholic Church for every one that joins 66% of “nones” agree that “religion causes more problems than it solves” That's why so many fall away from the Faith.  The Church doesn't seem relevant to them because she doesn't seem like she has the answers to the real issues they face. 10% of American adults are former Catholics Nearly half of those who fall away from the Church become "nones"  And another quarter become Evangelical Christians.   79% of former Catholics leave the Church before age 23.   50% of Millennials raised Catholic no longer identify as Catholic today  And it's about topics like anger -- we are not doing a good job meeting the needs that Catholics have today, human formation needs.   Intro I am Dr. Peter Malinoski, a.k.a. Dr. Peter, clinical psychologist, trauma therapist, podcaster, blogger, cofounder and president of Souls and Hearts -- but most of all I am a beloved little son of God, a passionate Catholic who wants to help you to taste and see the height and depth and breadth and warmth and the light of the love of God, especially God the Father and  Mary our Mother, our spiritual parents, our primary parents.  To really absorb your identity as a little child of God and Mary.   I want you to enter much more deeply into an intimate, personal, loving relationship with the three Persons of the Trinity and with our Lady. That is what this Interior Integration for Catholics podcast is all about, that is what Souls and Hearts is all about – all about shoring up the natural foundation for the spiritual life of intimacy with God, all about overcoming the natural human formation deficits and obstacles to contemplative union with God our Father and our Lady, our Mother  We are on an adventure of love together. And one thing, one major, big, huge thing that gets in the way of being loved by God and Mary and loving in return is anger.  Anger.   This is Episode 103 of Interior Integration for Catholics.  Interior Integration for Catholics is part of Souls and Hearts, our online outreach, check us out at soulsandhearts.com.   Anger: one of the seven deadly sins, one the lethal vices that can kill your soul.  Anger.   So much confusion about anger.  The Burden of Anger:  June 10, 2021 Catholic-daily-reflections.com The first level of sin is simply to be “angry” interiorly. The sin of anger is an interior attitude of disgust toward another. Jesus says that the consequence of having anger toward another is that you will be “liable to judgment.” Humility.  I could be wrong.    The offerings from Five Catholic writers on anger are a case in point.   The most popular book Fr. T.G. Morrow, Overcoming Sinful Anger  303 Amazon Review, mostly positive, #16  on the list of bestsellers in Catholic Theology, put out by Sophia Press in 2015 And it's not very good.  I can't recommend it.   First off, Fr. Morrow admits that he doesn't understand why people get angry We've all encountered people who explode when they feel angry. It baffles me how often the sort of anger rears its ugly head in marriages – even in allegedly Christian marriages. (p. 9).   I am often surprised to discover Christians who pray ardently, receive the sacraments regularly, we've and attend Mass daily, and yet have an anger problem. (p. 10) Presumes a homogeneous, single personality.   Easy to explain with part.   Why do people explode in anger? There are many reasons, but I think the top three are power and control, a refusal to take responsibility, and habit. (p. 13). Very simplistic view of psychology, and no consideration of neurology, traumatology,  Confusion about the causal chain in anger.  Where anger fits in a sequence of events  Little genuine interest in anger.  Anger is something to essentially get rid of.   Not much consideration of the unconscious and unconscious anger.  Acknowledges that suppressing anger is problematic, but there still is an assumption that if I'm not feeling anger, it's not there.  Disconnect.   "Irrational anger"   Very focused on the will and will training -- naïve assumptions about sympathetic arousal. Nike Spirituality -- Just do it.   Romans 7:15:  I do not understand my own actions. For I do not do what I want, but I do the very thing I hate.   Spiritual Bypassing  Definitions John Welwood: American clinical psychologist, psychotherapist, teacher, and author, known for integrating psychological and spiritual concepts  Using “spiritual ideas, words and practices to sidestep or avoid personal, emotional ‘unfinished business,' to shore up a shaky sense of self, or to belittle basic needs, feelings, psychological wounds and developmental tasks.”  Blogger Rose Hahn:  Spiritual Bypassing: What It Is & How To Avoid It  Bypassing occurs when spiritual ideals get elevated to the realm of absolute truth in such a way that our real, lived experience is somehow denied. Rather than doing the work of healing deep wounds, we may use these ideals to deny, devalue, or avoid meeting our more human needs – such as emotional bonding, love, and esteem. In other words, rather than risk opening ourselves to real human connection, and possibly get hurt, we adopt a more enlightened, spiritual way of relating to the world that doesn't rely on human relationship.  Not a lot from a specifically Catholic perspective, but this is from Katharina, who styles herself "The Bohemian Catholic" We are supposed to uplift each other, and treat each other with love and respect - like icons of Christ, as God's creation… BUT if you find yourself trying to tell someone that their faith should keep them "happy" all the time, then you aren't helping them.  Using spiritual words, spiritual means, spiritual concepts -- all to whitewash or put a Band-Aid on significant psychological or emotional problems in the natural realm  Bypassing the natural realm and going to the spiritual realm.   Essentially saying -- You should not feel this way.  Which is what Fr. Morrow is saying.  He promises to "I will offer some ideas, which I consider quite novel, on how to avoid angry explosions." (p.4) Tips So, as a first step in overcoming passive-aggressive anger keep reminding yourself that you want to be a Christian, and therefore you can't take revenge anymore. (p. 9).  First, take the time to calm down and figure out why you're angry…. One of the tactics often recommended is to count to ten before deciding what to do. (p. 20).  Better still, say a short prayer before acting. The next step is to ask yourself if your angry feeling is been caused by something significant. Most angry fights in marriage are caused by trifling things. (p. 20).  Or perhaps use humor to make your point.(p. 20).  Offering your angry feeling as a sacrifice is not suppressing it but doing something with it. It is making a bad situation into a beneficial one. That is what it means to embrace the cross. (p. 23-24).  If we can forgive others, we can pull the rug out from beneath our anger most of the time. Unforgiveness is the main culprit behind anger. (p. 25).  … Refocus your thoughts away from the things that made you angry to some very positive thoughts. For example, thank God for the beautiful weather for the ability to read or buy things you need. (p. 30).  I often encourage people with an anger problem to daily for humility. It works. (p. 36).  Chapter 7: Thanking God, praising God  Consider your future. One key way to change her behaviors to work on in your mind just what your life will be like if you don't change your angry behavior. (pp. 72-73)  If you struggle with an anger problem write on an index card all the negatives of continuing your anger and read that list several times a day. (p. 74).   Fr. Joseph Esper, Saintly Solutions to Life's Common Problems  99 reviews on amazon.  #138 in Roman Catholicism.  2001 Book -- First Chapter is on anger.   St. Thomas of Villanova: "Dismiss all anger and look into yourself a little." (p. 7) "St. Francis de Sales advises that, to avoid the sin of anger, you must quickly ask God to give peace to your heart when you're angered and then turn your thoughts to something else. Don't discuss the matter at hand or make decisions or correct other person while you're angry. When a person angers you, St. Francis advises, consider the person's good qualities rather than the words or actions you find objectionable." (p. 7) When we have to speak to someone with whom we are angry, we should first pray for the Lord's guidance and help. It's often more effective to speak in terms of asking favors, rather than making demands or giving orders…" (p. 5-6) ...rehearse possible responses and evaluate which ones which might help you. (p. 7) Tommy Tighe St. Dymphna's Playbook: A Catholic Guide to Finding Mental and Emotional Well-Being 2021 book,  #57 in Christian Pastoral Counseling, 66 reviews, mostly positive.   Doesn't discuss anger.  Discusses irritability as a symptom of depression and resentment as a problem in relationships "However, the more I have experienced depression in my own life and in my work as a clinician, the more I have seen the symptoms of irritability and anger is predominant features of depression." (p. 13).  That's one way, not the only way.   So often depression results from  Recommendations "…go for a walk, take some time to meditate, watch or read something that lightens our mood. (p. 13)  "Keeping a diary of our emotions and reactions to those emotions is a great place to start… Look back on a situation, slow it down, and examine what exactly happened….We might ask ourselves: What is it that has led to my irritability? Is it because I'm depressed and trying to stuff that feeling down rather than address it? What am I thinking in that situation? (p. 15).  "We draw this all out on paper, examine what was really behind our emotional response, and then explore ways of thinking that will restructure our reactions and response. And we write these down! Simply thinking about these things isn't going to help. The whole point is to get them out of our head and onto paper so that we can work them out. Consider it an emotional "show your work" kind of exercise." (p. 15).  Then, after a really brief introspective process, we can catch that the real reason for our irritability is our depressed mood, and we can interject coping skills for depression to stave off our irritability. (p. 16).  Changing the focus of our thinking is key when we try to battle against depression and irritability that inevitably rears its ugly head. You've probably heard people suggest keeping a gratitude list to help you feel more positive, much along the same lines as St. Paul's advice. It works. (p. 18).   Steps in the process Visualize yourself from the perspective of compassionate observer.  Notice from the outside whole feelings xare upsetting you and how they are reflected in your appearance.  Try to let the warm feeling of compassion and desire to help arise within you.  Say to yourself: "It is understandable that you feel that way. You are experiencing a natural response to depressing thoughts. But I'm going to help you."  Visualize putting your hand on your shoulder or hugging yourself to soothe and comfort yourself. Give yourself a friendly smile.  Think about if there are other things you want to tell yourself that would energize and encourage you to cheer up.  Taking time to say those things. When you feel it is appropriate, begin saying goodbye to yourself and remind yourself that you come back anytime you want. (p. 16-17). For resentment: Active listening  Tommy Tighe: to fend off resentment, we have to communicate with things are important to us and why. We can't expect our partner to read her mind. We have to tell them the things we value, what things we have grown to expect in relationships because of our past experiences and we have to tell them why. (p 113)   Rhonda Chevrin Taming the Lion Within: 5 Steps from Anger to Peace 2017  16 ratings  is a Catholic author, international speaker and Professor of Philosophy. She is the author of over 60 books concerning the matters of Catholic thought, practice and spirituality,  Take a secure thought -- use your imagination to think of ways out of annoying or enraging situations   Avoid exceptionality.  Accept the averageMove your musclesHumor is your best friendF.I.S.T.  Feelings, Impulses, Sensations, Thoughts:  What it signifies is that we can control our immediate impulses and sensations when hurt or frustrated, but if we control our thoughts we can control her impulses.Put your mental health firstPeace over power:  Many times you can't win, and it doesn't matter if you lose.  It's not worth the effort to put up a fight.  They are not doing it to you; they're just doing it! – Much is not done on purposeNot a 911  Not everything is an emergency,.Be Group minded Anger at GodForgiveness  Fr. Spitzer Angry with God? Here's Fr. Spitzer's Advice on How to Overcome Anger God understands your anger.  Don't dwell on it.  Don't go there.   Choose instead to: Three step process in the YouTube clip Angry with God:   Stop comparing to the way you once were.   Stop comparing yourself to others.   Stop having expectations for your suffering.   Offer it up.  Stop the questioning.   Saints' behaviors  Meg Hunter-Kilmer - published on 09/28/17Aleteia September 28, 2017, What We Probably Don't Know about St. Jerome Is Just What We Need to Know St. Jerome was known to carry around a stone that he would hit himself with every time he lost his temper.     If these are helpful to you, great.  I don't want to put up roadblocks.  Might be helpful to many people.   As a Catholic psychologist, I am not comfortable recommending any of these Catholic sources Very simplistic view of psychology, and no consideration of neurology, traumatology,  Confusion about the causal chain in anger.  Where anger fits in a sequence of events  Little genuine interest in anger.  Anger is something to essentially get rid of.   Very focused on the will and will training -- naïve assumptions about sympathetic arousal.  And they don't get that anger has a protective function -- to protect us against shame.  Not one of those sources connects anger to shame.  And that's the primary connection we need to understand if we want to resolve anger, not just try to shoo it away.   What are we talking about when we discuss anger -- let's get into definitions of Anger Focused on vengeance secondary to a desire -- more than an emotion.   Written discussions of anger in the western canon go back as far as fourth-century BC in Greece when the philosopher Aristotle (384-322 B.C.) argued that anger is a rational and natural reaction to being offended and thus is closely associated with reason. In the Rhetoric (1991, p. 1380) he defined anger as “a belief that we, or our friends, have been unfairly slighted, which causes in us both painful feelings and a desire or impulse for revenge.” 1907 Catholic Encyclopedia:  Anger:  The desire of vengeance. Its ethical rating depends upon the quality of the vengeance and the quantity of the passion. When these are in conformity with the prescriptions of balanced reason, anger is not a sin. It is rather a praiseworthy thing and justifiable with a proper zeal. It becomes sinful when it is sought to wreak vengeance upon one who has not deserved it, or to a greater extent than it has been deserved, or in conflict with the dispositions of law, or from an improper motive. The sin is then in a general sense mortal as being opposed to justice and charity. It may, however, be venial because the punishment aimed at is but a trifling one or because of lack of full deliberation.  Likewise, anger is sinful when there is an undue vehemence in the passion itself, whether inwardly or outwardly. Ordinarily it is then accounted a venial sin unless the excess be so great as to go counter seriously to the love of God or of one's neighbor.   CCC 2302  By recalling the commandment, "You shall not kill," our Lord asked for peace of heart and denounced murderous anger and hatred as immoral. Anger is a desire for revenge. "To desire vengeance in order to do evil to someone who should be punished is illicit," but it is praiseworthy to impose restitution "to correct vices and maintain justice." If anger reaches the point of a deliberate desire to kill or seriously wound a neighbor, it is gravely against charity; it is a mortal sin. The Lord says, "Everyone who is angry with his brother shall be liable to judgment."  Contradiction that aggression (or vengeance) and anger have to go together  Lot of research to tease about anger and aggression: Ephesians 4:26:  Be angry but do not sin; do not let the sun go down on your anger   APA Dictionary of Psychology: an emotion characterized by tension and hostility arising from frustration, real or imagined injury by another, or perceived injustice. It can manifest itself in behaviors designed to remove the object of the anger (e.g., determined action) or behaviors designed merely to express the emotion (e.g., swearing). Anger is distinct from, but a significant activator of, aggression, which is behavior intended to harm someone or something. Despite their mutually influential relationship, anger is neither necessary nor sufficient for aggression to occur.  Psychologist Paul Ekman. (1999). Basic emotions. In T. Dalgleish & M. J. Power (Eds.), Handbook of cognition and emotion (pp. 45–60). John Wiley & Sons Ltd  Due to its distinct and widely recognizable pattern of face expression, anger has always been included in the repertoire of basic emotions.   Benefits of Anger  Farzaneh Pahlavan Multiple Facets of Anger: Getting Mad or Restoring Justice?  Chapter 3:  The Neurobiology of RAGE and Anger & Psychiatric Implications with a Focus on Depression Daniel J. Guerra1, Valentina Colonnello and Jaak Panksepp As a basic emotion, anger emerges early in life and has a unique adaptive function in motivating, organizing, and regulating behavior. No other emotion can match the consistency and vigor of anger in mobilizing high-level energy and sustaining goal-directed activity. Anger serves a variety of regulatory functions in physiological and psychological processes related to self-defense as well as to interpersonal and societal behaviors. Through socialization processes, it plays an important role in the development of personality and individual differences in responding to environmental challenges, which can be more or less adaptive.  (p. v).   Aristotle:  Aristotle: Nichomachean Ethics: It is easy to fly into a passion – anybody can do that – but to be angry with the right person into the right extent and at the right time and with the right object in the right way – that is not easy, and it is not everyone who can do it  In themselves passions are neither good nor evil. They are morally qualified only to the extent that they effectively engage reason and will….It belongs to the perfection of the moral or human good that the passions be governed by reason. CCC 1767  CCMMP: Catholic-Christian Meta-Model of the Person  DMU Paul Vitz, William Nordling, Paul Craig Titus.    p. (294)  to remain in the virtuous middle ground requires being disposed to a righteous anger that will stand up to injustice, and use a good measure of anger in ways that are corrective of the evil, preventive of further injustice, and indicative of a balance to mean between extremes. Emotions are good when, as reactions antecedent to reasoning, they make us conscious of reality and prepare us for a more complete reaction and moral action. Emotion and choice then serve moral flourishing (e.g., when we have an appropriate spontaneous reaction of anger at injustice). Second, emotions are good as felt reactions that also follow the intellectual evaluation of the situation. Emotions can be expressive of rational decisions. Emotions can thus participate in our life of reason and will (Gondreau, 2013). For example, when we choose to rectify and injustice, a balanced expression of anger can help us to act decisively will being restrained enough that we do not overreact. Through a righteous or just expression of anger, we entered rectify injustice, will finding a just and rational mean between excessively weak or exceedingly strong emotional displays. (p. 650). Emotions are viewed as informing people about their cares and concerns. To prepare the body for action, directing our thoughts to ways that will appropriately address the issues at hand. They can signal and manipulate other people in ways that suit the person's emotional needs (Parrott, 2001). Being disconnected from emotional experience, therefore, means being cut off from adaptive information (Pos et al., 2003). (pp. 650-651). Digression into justification of secular sources Question may arise, "OK, Dr. Peter, as you already noted, anger has been recognized for a long time, going all the way back to Aristotle and way before that in Sacred Scripture.  You emphasize that you are a Catholic psychologist, so why are you even looking at these secular sources like the American Psychological Association? There is a lot about anger in Scripture, in the Church Fathers and the saints about anger in the spiritual life.   Discalced Carmelite Abbott Marc Foley in his excellent book The Context of Holiness: Psychological and Spiritual Reflections on the Life of St. Therese of Lisieux "One…misconception is that the spiritual life is an encapsulated sphere, cloistered from the realities of daily living….we have only one life composed of various dimensions.  Our emotional life, intellectual life, social life, work life, sex life, spiritual life are simple ways of speaking of the different facets of our one life.  (p. 1).  We have one life.  One life.  We don't have a spiritual life that is separate from our emotional life.  We have one life.  If we are angry, that affects our whole life.   The Church herself encourages us to look to all branches of knowledge and glean what is best from them in order to live our one life better.  From the CCC, paragraph 159  "Though faith is above reason, there can never be any real discrepancy between faith and reason. Since the same God who reveals mysteries and infuses faith has bestowed the light of reason on the human mind, God cannot deny himself, nor can truth ever contradict truth." "Consequently, methodical research in all branches of knowledge, provided it is carried out in a truly scientific manner and does not override moral laws, can never conflict with the faith, because the things of the world and the things of faith derive from the same God. The humble and persevering investigator of the secrets of nature is being led, as it were, by the hand of God in spite of himself, for it is God, the conserver of all things, who made them what they are." And from the Vatican II document, the Pastoral Constitution of the Church in the Modern World, paragraph 62 reads:  In pastoral care, sufficient use must be made not only of theological principles, but also of the findings of the secular sciences, especially of psychology and sociology, so that the faithful may be brought to a more adequate and mature life of faith. Remember that we are embodied beings -- we are composites of a soul and a body. The 17th Century Philosopher Rene Descartes' popularized what is called mind-body dualism.  Mind-body dualism is the idea that the body and the mind operate in separate spheres, and neither can be assimilated into the other.  And that is false.  Demonstrably false in a lot of ways, be we so often assume it to be true.  We have one life.   In the last several years we are realizing just how much of our mental life and our psychological well-being is linked in various ways to our neurobiology -- the ways that our nervous systems function.  And the relationship between our embodied brain and our minds is reciprocal -- each affects the other in complex ways that we are just beginning to understand.  In other words, brain chemistry affects our emotional states.  And our emotional states and our behaviors affect brain chemistry.  It's not just our minds and it's not just our bodies and it's not just our souls -- it's all of those, all of what makes me who I am, body, mind, soul, spirit, all of it.   And since Scripture, the Early Church Fathers, the Catechism and so on are silent on neurobiology, neurochemistry, neurophysiology and so many other areas that impact our minds and our well-being, as a Catholic psychologist I am going to look elsewhere, I'm going to look into secular sources.  I just don't think it's reasonable to expect the United States Conference of Catholic Bishops or the Congregation for the Doctrine of the Faith in the Vatican to be experts in these areas -- it's not their calling, it's not their expertise.  St. John of the Cross in his  Prologue of Ascent of Mt. Carmel: "I will not rely on experience or science…[but] I will not neglect whatever possible use I can make of them.  Fr. Marc Foley, OCD : The Context of Holiness:  As St. Thomas wrote of St. Augustine's use of Platonic philosophy in the Summa: "whenever Augustine, who was imbued with the doctrines of the Platonists, found in their teaching anything consistent with the faith, he adopted it and those things which he found contrary to the faith he amended." (ST I, q. 84,a. 5) p.4 And St. Thomas himself drew on so much of Aristotle's thought in his writings, bringing it into his body of work.   Abbot Marc Foley.  In short, we should never swallow the school of thought whole; we should sift the wheat from the chaff, separate truth from falsehood. p.4 We want the best from all sources.   Emphasis on biological processes:   From Heidi Crockett Anger Management with Interpersonal Neurobiology  Discussed Interpersonal Neurobiology at length in  Episode 92 of this podcast Understanding and Healing your Mind through IPNB In interpersonal neurobiology, anger as an emotion is viewed from the perspective of cognitive neuroscience. And cognitive neuroscience states that cognition and emotion are dynamically combined with physical arousal. When anger is induced as an emotion in humans, it can unconsciously affect physiological and neural resources. Affective states of anger are subsequently expressed in the brain as well as the body, and these neural and physiological changes can influence the cognitive processes. Many studies and resources have been expended on studying the emotions of happiness, sadness, and fear, which align with psychopathological states of hypomania, depression, and anxiety. Kathy Steele, Suzette Boon, Onno van der Hart:  Treating Trauma-Related Dissociation: A Practical, Integrative Approach:  Anger is an affect to derived from activation of the sympathetic nervous system, geared to energize the body for maximum effort to fend off perceived danger. Psychologically, it protects from awareness of vulnerability and lack of control, and therefore from shame. And fight mode, we are all primed to perceive cues of danger rather than cues of safety and relational connection. In such a heightened state of arousal, it is easy to misunderstand the intentions of others. (p.332). Polyvagal theory and anger  A critical period for experience-dependent development of the feelings of safety during early infancy: A polyvagal perspective on anger and psychometric tools to assess perceived safety  Frontiers in Integrative Neuroscience July 2022 article   Andrea Poli, Angelo Gemignani, Carlo Chiorri and Mario Miccoli Brief primer here on some neurology.  Don't worry.  I will keep it simple.   Neurons are specialized cells that receive and send signals to other cells through fragile and thin cellular extensions called axons. Myelination:   a membrane or a sheath around the axons on neurons.   Myelinated axons often have a larger diameter Myelinated axons are insulated Myelination allows for much faster transmission of electric impulses Presence of safety during the critical period (first year of life).   Decreased unmyelinated/myelinated cardioinhibitory fibers ratio in adulthood Ventral Vagal complex is able to have a greater impact on reducing the Sympathetic Nervous System arousal -- decreasing anger  VVC is able to have a greater impact on reducing Dorsal Vagal Complex fear and shutdown responses -- the freeze response.   Greater capacity for self-regulation.   Absence of safety during the critical period  Increased unmyelinated/myelinated cardioinhibitory fibers ratio in adulthood Ventral Vagal complex has a lesser impact on reducing the Sympathetic Nervous System arousal -- less able to decrease sympathetic arousal, including anger  VVC has a lesser impact on reducing Dorsal Vagal Complex fear and shutdown responses -- less able to reduce the freeze response.   Less capacity for self-regulation.   Dampened VVC activity reduces the capacity of adaptive inhibition of SNS and DVC (Dorsal Vagal Complex), and emotional self-regulation. Hence, environmental detection of unsafety cues may preferentially trigger SNS-mediated anger in order to avoid DVC-mediated immobilization with fear. Young children exposed to five or more significant adverse experiences in the first three years of childhood face a 76% likelihood of having one or more delays in their language, emotional or brain development. (6) As the number of traumatic events experienced during childhood increases, the risk for the following health problems in adulthood increases: depression; alcoholism; drug abuse; suicide attempts; heart and liver diseases; pregnancy problems; high stress; uncontrollable anger; and family, financial, and job problems. (6) 7 ways childhood adversity changes a child's brain Donna Jackson Nakazawa Acestoohigh.com website September 8, 2016 Epigenetic Shifts  gene methylation, in which small chemical markers, or methyl groups, adhere to the genes involved in regulating our stress response, and prevent these genes from doing their jobs.  Size and Shape of the Brain stress releases a hormone that actually shrinks the size of the hippocampus, an area of our brain responsible for processing emotion and memory and managing stress.  Chronic neuroinflammation can lead to changes that reset the tone of the brain for life   Brain connectivity:  Dr. Ryan Herringa, neuropsychiatrist and assistant professor of child and adolescent psychiatry at the University of Wisconsin, found that children and teens who'd experienced chronic childhood adversity showed weaker neural connections between the prefrontal cortex and the hippocampus. Girls also displayed weaker connections between the prefrontal cortex and the amygdala. The prefrontal-cortex-amygdala relationship plays an essential role in determining how emotionally reactive we're likely to be to the things that happen to us in our day-to-day life, and how likely we are to perceive these events as stressful or dangerous. Including anger.   Wiring of the brain and nervous system matter -- they matter a lot Brain activation in anger  Distinct Brain Areas involved in Anger versus Punishment during Social Interactions  Olga M. Klimecki, David Sander & Patrik Vuilleumier Scientific Reports 2018. 25 men fMRI study anger induced in an in inequality game designed to be unfair.   In the present study, we found that the intensity of experienced anger when seeing the face of the unfair other was parametrically related to activations in amygdala, STS (superior temporal sulcus), and fusiform gyrus (related to facial recognition). The STS has been shown to produce strong responses when subjects perceive stimuli in research areas that facial recognition   Farzaneh Pahlavan Multiple Facets of Anger: Getting Mad or Restoring Justice?  Chapter 3:  The Neurobiology of RAGE and Anger & Psychiatric Implications with a Focus on Depression Daniel J. Guerra1, Valentina Colonnello and Jaak Panksepp Rage emerges when specific environmental stimuli arouse the neural circuitry of the RAGE system. Even if the anger-thoughts and the related expression are modulated and regulated by higher cortico-cognitive areas, the human basic circuitry of anger is still subcortical. Since the early description of rage in decorticated cats (Dusser De Barenne, 1920) and dogs (Rothmann, 1923) and their responses to inoffensive stimuli, it was clear that the rage expression is i) dependent on subcortical areas, i.e. the ancient regions play a crucial role more than the higher neocortical regions; ii) independent of an intact cortex. p. 11  Among the higher limbic regions of this network, the medial nucleus, the basal complex, and central and lateral nuclei of the amygdala play a key role in the modulation of RAGE.  p. 1   All this happens far away from the frontal cortex in the limbic system of your brain.   Kathy Steele, Suzette Boon, Onno van der Hart:  Treating Trauma-Related Dissociation: A Practical, Integrative Approach   Why of Chronic anger.   Anger is the primary emotion of the "fight" defense.  When (parts of) the patient become stuck in this defense, anger becomes chronic.  Thus, the first intervention is safety.  332 As long as a fight reaction remains unresolved, anger will remain chronic. (p.332).  Almost no one seems to understands that anger is a defense against fear and shame.  It's a way of trying to protect oneself.   There are several reasons that anger and hostility become chronic in dissociative patients. First, patients typically have been severely invalidated, ignored, heard, betrayed, and sometimes even tortured over extended periods of time, while helpless to stop it. In itself, this is enough to generate enormous rage in anyone as part of the naturally occurring fight defense. Second, as children, patients often had little to no help in learning how to regulate and appropriately express normal anger, much less how to cope with it. Often it was unacceptable for many patients to express any kind of anger as children, while the adults around them were uncontained and highly destructive with their anger. Others had no limit set on their angry behaviors. (p. 330). Angry dissociative parts are feared and avoided internally by most other parts, particularly those that function in daily life. After all, angry behaviors toward self and others may interfere with functioning in a variety of personal and social ways. An ongoing vicious cycle of rage and shame ensues internally: the more patients avoid their angry and destructive dissociative parts, the angry these parts become, and the more they shame other parts and are shamed by them. (p. 331). … Angry parts have a deep shame and are highly defended against the strong belief that they are very bad. Their defense is reinforced by the shame of patients that such parts of themselves even exist. These parts of the patient are terrified of attachment to the therapist and you the relationship is dangerous, mainly because they are afraid that the therapist will never accept them. (p. 331-332). Whether the anger is part of a fight response or not, it is often a secondary emotion that protects the patient from feelings of sadness, extreme powerlessness, shame, guilt, and loss. (p. 333).  (add grief) Parts of the patient that developed  controlling-punitive strategies will be angry with others to get what they need,  while those that have controlling-caregiving strategies will punish themselves for being angry or having needs. (p. 333).  This is often the case in hostile parts such as those of self-injure or encourage other parts to self-harm, prostitute themselves, abuse drugs or alcohol, or engage in other self-destructive behaviors. They are often stuck in destructive and harmful behaviors that are an "attack self" defense against shame. (p.333). Finally, the rage of the perpetrator is often an embodied experience from which patients cannot yet escape without sufficient realization and further integration. Some dissociative parts imitate perpetrators internally, repeating the family dynamics from the past with other parts in a rather literal way. (p.333). "Getting the anger out" is not really useful, as the problem is that the patient needs to learn how to effectively express anger verbally rather than physically, and in socially appropriate and contained ways, so the patient can be heard by others. It is less the fact that patients express anger, but how they do so and whether that expression allows him to remain grounded in the present, to retain important relationships, and to avoid being self-destructive. (p. 334). Expression of anger is not necessarily therapeutic in itself. It is how (parts of) the patient experience and express it that is important; whether it is within a window of tolerancex in a socially appropriate and safe. Therapist must learn when expression of anger is therapeutic and when containment of anger is more helpful. (p. 334). Working with anger an angry parts (p.335). Take the time to educate the patient as a whole about the functions of anger and angry parts. Although they may seem like "troublemakers," they can be understood as attempting to solve problems with ineffective or insufficient tools.  Encourage all parts of the patient understand, accept, and listen to angry parts, instead of avoiding them.  Make efforts to understand what provokes angry parts. There are many potential triggers.   Not direct quotes Do all parts feel the same way as the angry part?  If not, can those parts listen to and accept angry parts perspective?  Would the angry part be willing to listen to the other internal perspectives?  Invite other parts to watch and listen if possible.  Can set limits with the angry part  the angry part and all parts need to learn that healthy relationships do not include punishment, humiliation, or force  Use titration, helping the person experienced as a small amount of anger will remain grounded in the present   Parts and imitate a perpetrator often literally experience themselves in our experienced by other parts as the actual perpetrator. Thus they understandably induce fear and shame within a patient as a whole, and sometimes fearing the therapist. (p. 345). The functions of perpetrator-imitating parts are (1) protect the patient against threats of the perpetrator, which continue to be experienced as real in the present; (2) defend the patient against unbearable realizations of being helpless and powerless as a child, (3) re-enact traumatic memories from the perspective of the perpetrator, as mentalize by the child; (4) serve as a defense against shame through attacking the patient and avoiding inner experiences of shame; (5) provide an outlet for the patient's disowned sadistic and punitive tendencies; and (6) hold unbearable traumatic memories. (p. 346). Suzette Boon, Kathy Steele, Onno van der Hart 2011 book  Coping with Trauma-Related Dissociation: Skills Training for Patients and Therapists Destructive expressions of anger include persistent revenge fantasies or actions, hurting self or others, "taking it out" on innocent people (or animals), or destruction of property. (p. 265).  Dissociative parts of a person that are stuck in anger may experience this feeling as vehement and overwhelming, often without words. They may have irresistible urges to act aggressively and have great difficulty thinking and reflecting on their feelings before acting. Angry parts have not learned how to experience or express anger and helpful ways. There are two types of anger dissociative parts. The first are parts that are stuck in a defensive fight mode, ready to protect you. Their anger at original injustices may be legitimate and naturally accompanies a tendency to strike out and fight, which is an essential survival strategy. However, such parts have become stuck in anger, unable to experience much else. They rigidly perceived threat and ill-will everywhere and they react with anger and aggression as their only option of response. Although these parts of you may not yet realize it, anger is often a protection against vulnerable feelings of shame, fear, hurt, despair, powerlessness, and loss. The second type of angry part may seem very much like the original perpetrator. They imitate those who hurt them in the past, and they can be experienced internally as the actual perpetrator. This experience can be particularly frightening, disorienting, and shameful. But be assured this is a very common way of dealing with being traumatized. In fact, although these parts may have some similarities to those who hurt you, they also significant differences: they are parts of you as a whole person, who is trying to cope with unresolved traumatic experiences. (p. 267)   Tips for coping with anger (p, 269 to 271) recognize how to make distinctions among the many gradations of anger, from mild irritation to rage, so that you can intervene more rapidly.  Understand your tells around anger, which may include a tight or tense feeling in your body, clenched jaw's or fists, feeling flushed or shaky, breathing heavily, heart racing, a feeling of heat, a surge of energy.  Empathize with her angry parts, recognizing they have very limited coping skills, and very limited vision. They've been shunned by other parts, left alone with their hurt, fear, shame, in isolation. This does not mean you have to accept their impulses toward inappropriate behavior  Once you start feeling some compassion toward these parts you can begin to communicate with them, listening with an intention, with curiosity to understand what lies underneath the anger  Angry parts have a strength, that they could transferred to use and more positive ways  Become more curious about why anger is happening.  Try creative and healthy nonverbal ways of expressing your anger, such as writing, drawing, painting, making a collage  Physical exercise may help as an outlet for the physical energy generated by the physiology of anger  Work on understanding your anger, by reflecting on it, rather than just experiencing it, being immersed in it. You might imagine observing yourself from a distance, and getting curious about why you feel the way you do.  Give yourself a time-out, that is, walk away from the situation if you're getting too angry. Counseling to 10, or even 200 before you say or do something you might regret later.  Calm breathing may help  Listen to each part of you, about what might help that part with anger. You can have in her conversations with parts of yourself about anger and how to express it. Small and safe ways to express anger can be negotiated that are agreeable to all parts of you  Watch safe people in your life and seal they handle their own anger. Do they accept being angry? Are they are respectful and appropriate with her anger? Are there particular strategies that they use that you could practice for yourself?  Healthy anger can get positive strength and energy. It can help you be appropriately assertive, set clear boundaries, and confront wrongs in the world. Anger can pave the way to other emotions, leading to the resolution relational conflicts.  We learn the most common triggers of your anger. Once you learn these triggers, you can be more aware when they occur and more able to prevent an automatic reaction of anger. Establish intercommunication among parts of yourself to recognize triggers and negotiate possible helpful strategies to cope with them rather than just reacting.  You can try allowing yourself to experience just a small amount of anger from another part of yourself: a drop, a teaspoon, 1% or 2%. In exchange you can share with angry parts feelings of calm and safety.  Inner safe spaces can be very helpful for childlike parts that feel terrified   My parts Feisty Part-- defends against shame -- Melancholio.   Good Boy  Challenger  Creative-distracting me.   Closing Mark your calendars.  Next Live Experience of the IIC podcast will be on Friday, January 13, 2023 from 2:00 PM to 3:00 PM Eastern time on Zoom (repeat) -- All about Anger -- dealing with your anger.  Going beyond what books can do.  Experiential exercise.  Links to register have gone out in our emailed Wednesday Reflections.  Can get the link on the IIC landing page as well, SoulsandHearts.com/iic  December 28, 2022  Reflection at soulsandhearts.com/blog  From Rejecting to Embracing Aging Reach out to me Crisis@soulsandhearts.com  Conversation hours:  cell is 317.567.9594 conversation hours 4:30 PM to 5:30 PM Eastern Time Every Tuesday and Thursday.   Resilient Catholic Community -- you do not have to be alone.   Why a deep intimate personal relationship with God our Father, Mary our Mother -- spiritual parents   By claiming our identity as beloved daughters and sons of God the Father and Mary our Mother. Identity is freely given.   How By dealing with the natural level issues we have, the human formation issues we have that have spiritual consequences.  Grace perfects nature  So many spiritual problems have their roots in the natural realm, in human formation.   If this kind of exercise is helpful to you, we have nearly 100 of them in the Resilient Catholics Community.   120 Catholics like you already on board, already on the pilgrimage -- just had 47 apply for the December 2022 cohort, excited to get to know our new applicants.   Closed December 31 -- wait list should be up soon for the June 2023 Cohort.   Get to know your own parts Get to love your own parts If interested, contact me.   Crisis@soulsandhearts.com 317.567.9594 conversation hours 4:30 PM to 5:30 PM Eastern Time Every Tuesday and Thursday.    

Irrigation is an important tool for a lot of farmers to take control of the weather. But there's also growing attention to how that water gets used on the farm, creating challenges. However, in the past few years the amount of data collected by irrigators and researchers is bringing much higher precision to the industry. One organization, the Irrigation Innovation Consortium, is helping to bring that data together to create better ways to use water for creating food.Amy Kremen is associate director of IIC, and she discusses the work of the organization, as well as how data is being put to use for agriculture. One topic she also explores is an attempt by several universities to work on creating a Master Irrigator program to boost knowledge and training for farmers who want to be even better stewards of the water they have available. She explores those topics in the latest episode of Around Farm Progress.

Summary:  In this episode, Dr. Peter brings together what we have been learning about receiving love in the story of Susanna Lead-in:  There is something in us, as storytellers and as listeners to stories, that demands the redemptive act, that demands that what falls at least be offered the chance to be restored. The reader of today looks for this motion, and rightly so, but what he has forgotten is the cost of it. His sense of evil is diluted or lacking altogether, and so he has forgotten the price of restoration. When he reads a novel, he wants either his sense tormented or his spirits raised. He wants to be transported, instantly, either to mock damnation or a mock innocence.”  Catholic Novelist Flannery O'Connor Intro.   I have been doing a lot of podcast lecturing.  Dense programming, lots of information.  Like Episode 99.  Not a bad thing.  But I want you to really take in what I'm offering at a bones level.  To possess it at the felt level, to be that familiar with it.  Not just head knowledge.  Whole self knowledge.   So I am going back to another way of learning, one I haven't emphasized enough.  Stories.  Today, I am going to tell you a story.  A story about receiving different kinds of love.  Why? Here's why.  In the words of Edward Miller tells us.  “Stories are our primary tools of learning and teaching, the repositories of our lore and legends. They bring order into our confusing world." Our primary tools for teaching and learning.  And it's true.  We teach our children in their earliest years through stories and experiences.  Not through lectures.   I am Peter Malinoski, clinical psychologist, passionate Catholic, co-founder and president of Souls and Hearts and soulsandhearts.com, and I am very pleased to with you as  your host and guide in this Interior Integration for Catholics podcast, episode 101 to be your storyteller, to tell you a story.  This episode is titled A Story about Receiving Different Kinds of Love -- a story we can all related to.   Prepping for the Story  Ways to Listen Listen to the Story  Listening to yourself as you listen to the Story.   What is going on inside Listen to your own parts Can pause the audio  Reflective space  What are your noticing  What are you resonating with in the story, what is impacting you.?  What are you rejecting   Parts -- Episode 71 A new and better way of understanding myself and others.   Needs  Primary Conditions for Secure Attachment Felt sense of safety and protection -- have to go through the valley of shame, fear, anger, grief  Feeling seen, heard, known and understood -- have to tolerating being in relationship, being present.   Feeling comforted, soothed and reassured  Feeling cherished, treasured, delighted in  Feeling the other has your best interests at heart   Integrity Needs My need to exist and survive  My need to matter  My need to have agency  My need to be good  My need for mission and purpose in life   Resistance to Being Loved from IIC 99  Limited vision and lack of imagination, leading to a refusal to be transformed by God We don't understand God's love The Costs of Being Loved by God Poor God images Poor Self images -- Shame Refusal to be vulnerable, to be exposed, to be revealed to God.  Lack of courage. Anger at God -- rebellion Cautions -- could be evocative for you -- parts of you may really connect in various ways.  I want you to take care of your self and your parts as you listen to the story.  If you need a break, take a break.   The Story -- Hero's Journey outline  The Ordinary World Susanna -- 40 year old married mother of three -- Brown hair, warm brown eyes, and easy smile, she laughs at your jokes -- the kind of person that you immediately felt comfortable with.  Open and engaging with other people, was well read, and could talk about your interests.  Socially adept, she coordinated making meals for local women who had babies.  Had a sense that she had suffered in her life and understood something about suffering.  And that was true Life wasn't always easy for Susanna Grew up in Culpeper, VA, 75 miles west of Washington DC, oldest of four children, all girls.  Named Susan.   Mother -- quiet, introverted - an interior designer turned homemaker.   Father -- extroverted, warm, gregarious high school teacher - taught algebra, geometry and trigonometry at Culpeper County High School  -- great sense of humor, gratifying, and a pretty easy grader, students loved him and he really liked being a popular teacher.  Strong sense that father had favorites among the daughters, and she wasn't one of them   When Susan was age 16, her mother divorced her father -- his affairs, excessive drinking Mother devastated.  Really wanted her daughter to understand.  Susanna was cold.   Read the divorce decree "Irreconcilable differences"  And she was so angry  At an emotional level, Susan repudiated both Mom and Dad.  Not understanding, not wanting to understand.   Decided to go by "Susanna" -- three reasons Devoted to the Chronicles of Narnia -- The last book of the series, The Last Battle.  Aslan says "Susan is no longer a friend of Narnia."  Given to nylons, lipstick, and party invitations -- she didn't seem serious  any more.   Susan was her given name -- she wanted different name, but not too different  In the Bible, in Daniel chapter 13, Susanna was the beautiful, faithful wife of Joakim.  She refused to be blackmailed into adultery by two respectable men of high stature in the community, two judges, who just happened to have also be voyeurs, peeping-Toms.  Susanna preferred death by denunciation rather than compromise her moral principles, and was saved by a young boy, Daniel, whose clever cross-examination of the accusers revealed them to be liars.  Susanna was a real heroine in her eyes, someone to be emulated.   Shuttling back and forth between parents, who were drifting from the Faith. Mom pursued an annulment got it, and remarried the summer after Susanna's graduation from high school.  Susanna refused to be in the bridal party, refused to go to the wedding.  Like many teenagers in this position, Susan rebelled.  But not by using alcohol, drugs or sex.  Susan rebelled by becoming more Catholic --  Went to Christendom college, it was close, it was Catholic.  She was determined to make a new life there.  Leave the old life behind.  Came home to see her parents as little as possible, focused on her sisters when she did come home.  Very uncommunicative with Mom and Dad.   Christendom is where she met Brett, who eventually became her husband.   Mathematics major, got into computer programming.  Very introverted, not very social.  Not socially awkward, exactly, but not at all inclined to parties and large groups.   Home based -- independent contractor.   High income Fantasy Role playing Games.   Children 16 year old Savannah, her oldest -- now driving and asserting her independence.   13 year old Trevor -- athlete, mechanically talented, liked woodworking  10 year old Micah -- still really cute and cuddly with Mom, starting to play volleyball and very into play dates with her friends.   The Call to Adventure Had been a freelance writer, mostly for Catholic publications, small but dedicated following. Made a little money.   Fr. Brownlee, the pastor asks her if she would consider being the assistant for ministry outreach at their suburban mega-parish.  Part time position.   Ray de la Cruz, the director for ministry outreach needed and assistant, just 10-15 hours per week, a lot of writing and some event planning, event management.   Fr. Brownlee, the pastor, love to have you on board, consider it -- Office at the parish, near the parish grade school, close to her two youngest kids.  A fit for her charisms.   Refusing the Call to Adventure She has a comfortable life, deciding not to do it.  Likes her home.   Brett starting to have some odd heart problems.  High blood pressure for years, stress of hitting deadlines.  Not doing as well.  Strange bodily symptoms, heart racing, no biological causes found.  Sometimes off of work for a week at a time, income not so stable.   Gnawing anxiety about that -- his father and grandfather had both died young.  She wasn't confident that she could handle the family finances if he died or became incapacitated.  Pushing it out of her mind.   Conflict increasing at home, especially between Trevor and Brett.   Need for human contact, writing getting lonely.  Brett not very good company right now, irritable, sad.    Maybe she does have something to offer.  Kids are more independent now, very busy.   Meeting the Mentor Ray, the director of ministry outreach -- really dynamic guy, lots of positive energy.  Brought in six months ago to revitalize the ministry outreach and find ways to really reach people, bring them more alive in the Faith.   Lots of initiatives across the different demographics of the parish.  Just needed a little help.   Susanna didn't know him well.  But from her vantage point, she did appreciate how he motivated people, how he stayed on his message of getting people to pray, to spend time with the Lord.  The Eucharistic Adoration chapel at the parish had been pretty moribund, but now it was lively, and teenagers from the youth groups were regularly taking hours in front of the Lord, even her daughter Savannah.  Ray was direct, straight-talking and had just come from significant success as an assistant VP in a mid-size marketing firm, but now was looking for more meaning and purpose in his life.  He was 38, had a few years in diocesan seminary, discerned out, and had never married.  He was doing an amazing outreach with the Latino community in the parish as well.   In the initial interview with Ray about the position, Susanna felt uplifted and supported.  She sensed that Ray was interested in her life, her background.  He discussed how he wanted to craft the position around the person -- around her -- capitalizing on her strengths, gifts, charisms, and not trying to fit her to some procrustean bed of a rigid position description.  And he really wanted to make sure that the position, if she took it, fostered her spiritual life.  "We have a start-up spirit here, not your same old parish corporate Catholicism" he said, laughing.  He was a fan of Dynamic Catholic and Matthew Kelly, had his books handy, Four Signs of a Dynamic Catholic was his favorite book, he told her.  So much in there we can learn to put in practice here.   Let me think about it.  Give me two weeks.  "OK, Susanna, you have two weeks.  Take all the time you need.  I'll be praying for you.  Just don't forget about me, OK, get in back in touch when you are ready."   If I am going to step back out in the world, I would want the position to support my spiritual life, foster my prayer life, help me toward holiness.  I would want someone in my corner, Susanna thought.  Someone who really had my back, someone that would advocate for me, some who understood me.  I need that.  If I start working outside our home again, I would need a supervisor who actually cares about me as a person not just what I can do for them.  Then with just a little twinge, a feeling she couldn't quite identify, the next thought came.  Someone like Ray.  She corrected herself.  Mr. De la Cruz.   Crossing the Threshold Ten days later she came back to the parish offices met  Ray and Fr. Brownlee in Ray's office and said, I'm in, but here's the caveat.  I want to try it for 90 days, see how it goes -- family life, how this sits with Brett, it's been a long while since I've been working in the world.   All right, Ray said, his face lighting up.  Let's do this -- and no worries, Susanna, this parish isn't the world,  You'll be working in the Church, not the world.  Fr. Brownlee shook her hand and smiled.  Have Martha onboard you with all the employment paperwork, she'll walk you through all that tedium.  I will let you and Ray figure out the details about how to work together, I trust you both, I have to go, financial reports for the Archdiocese are waiting.  You know how to reach me if you need something.  God bless.   Let's start with prayer, said Ray.  And without waiting for her to answer, he prayed out loud, thanking God for the parish, for Fr. Brownlee, for the outreach work, the work of evangelization, for the beauty of the day, and for Susanna joining the staff, bringing all her gifts and talents and her whole being to the team.  Then he made the sign of the cross.   All right, Ray said again, let's shake on the deal.  He held out his hand and she shook it, and felt a ripple of electricity surges up her arm as he gave her a quick squeeze before releasing.  She felt excited, was she really happy?  She hadn't sensed such an uplift in a long time.  I must have gotten older than my years somehow, she thought to herself.  She smiled warmly at him and he laughed again and asked "what's your schedule for today?   Test, Allies, Enemies The next six month seemed like a whirlwind to Susanna.   She absolutely embraced the parish work. Her confidence rose week by week.  Ray was able to find just the right growing edges for her, to really stretch her but not overwhelm her.  They read passages from Matthew Kelly's book "The Dream Manager" and brainstormed together about her professional development.   Susanna did most of the planning for the eighth grade retreat, and her son Trevor said that all his friends at school thought it was the best retreat ever.   Susanna connected with Martha, the parish administrative assistant and Sharon, the school principal, who also took an interest in her and appreciated her eating lunch with the students including Trevor and Micah on occasion.   And she made a lot of mistakes, there was a steep learning curve for Susanna.  Ray laughed them off with one or more of his inexhaustible supply of quotes.   For the eighth grade graduation supper, Susanna caused great commotion with a caterer -- Susanna had made several errors in placing the order and then alienated the caterer in her frantic attempts to force everything to work out.  Multiple different entrees had to be prepared in an emergency, the food quality suffered and worst of all, all Trevor's classmates knew it was Susanna's fault.  The caterer complained about Susanna to the pastor and the auxiliary bishop.   Susanna felt terrible, ashamed, and guilty.  Ray wasn't fazed by it at all. He just quoted the business magnate Richard Branson  who said "You don't learn to walk by following rules. You learn by doing, and by falling over."   That was so refreshing for Susanna, who ever since her parents' divorce had been so focused on not making mistakes.  She began to realize that she saw her parents' divorce as a huge mistake, she never wanted to make a mistake like that, and the best way to avoid making such a huge mistake was to make no mistakes at all.  She began to feel more free, like the world was a little more spacious.   At Ray's insistence, Susanna had dispensed with calling him Mr. De la Cruz after the first meeting.  My name's Raimundo, but just call me Ray.  Everyone does." And everyone did, even the school kids and the youth of the parish.   Ray seemed to have unbounded energy and no end of creative ideas.  He also took prayer seriously -- Early in the morning, Susanna would see him in the Adoration chapel.  He invited her to pray with him before they met to discern and discuss plans.  He inquired about her prayer life -- and let her know that he was continuing to pray for her, that she be a saint.  He asked her to pray for him.  And amazing things were happening in the parish.  Ray was a dynamic motivational speaker, especially for the teenagers and the young adults, and he had a way of connecting with the men of the parish as well.  He had a remarkable ability to remember names.  Susanna found herself admiring him.   She grew more and more curious about him, and what made him tick, where did he get all the energy and enthusiasm?  He never seemed to have a bad day.  He had the full support of the pastor and a lot of autonomy.   Her daughters noticed that Mom was happier and busier.  Her husband Brett seemed to be noncommittal about her working at the parish.  But he was in his funk still, and Susanna began to wonder if he might be depressed.  It was hard to know, he was so hard to reach in so many ways.   Her own prayer life was growing -- the challenges she was facing encouraged her to pray.  And now she had two teenagers, with their trials and their hormones to deal with.  Trevor, now in high school, occasionally would ask "How's it going for you, Mom at work.?  How's Ray?"  Susanna found herself tongue-tied trying to explain what her work was like to Trevor.   Susanna experienced some confusion and a vague sense of guilt about her marriage.  She struggled with how to love Brett, who so needed space and whose love languages seemed so different from hers.   He seemed even more uncomfortable with touch than in years past, with physical affection unless he had been drinking.  She had a sense that he didn't fully approve of her working at the parish, but he would not come out and say what he thought.  He was so indirect.  Why could that man not support her in something that she found joy and purpose and meaning in?  It troubled her.   Very gradually, over time, Ray became even more casual and familiar in his conversation with Susanna.  Sometimes he would call her "Susanita" and playfully refer to Susanna as his "guiding star" when she had a particularly creative idea.  He had an amazing vocabulary in multiple languages.  Once in a while, when he was in a particularly warm mood, he would refer to her with terms of affection in other languages -- querida, cara, carino, mon chéri.  She asked him about that.  He responded with a big smile and his arms open wide, I'm from Puerto Vallarta in Jalisco, We talk like that there, they are just ways of expressing friendship and connection.  And I consider you more than just my assistant.  I think we are spiritual friends -- at least I hope we are.  Like St. Francis de Sales and St. Jane de Chantal.  But hey, if it bothers you, I won't use those words,  I can just call you Susanna.  No problem."  "No, no it's ok, I kind of like it.."  Great, said Ray.  Susanna, I just want to be a Ray of sunshine in your life, and he laughed heartily at his own play on words.  But those words stayed with Susanna and echoed in her memory.   A Ray of sunshine in my life.    Three weeks later, at the end of the day.  Susanna stopped by Ray's office to drop off a file and saw him head down in his chair, shaking.  "Ray?"  "Ray, are you all right?"  He took his hands from his face, eyes streaming with silent tears. "No."  "I'm not all right."  "I'm very not right."  Susanna immediately pulled up a chair next to his, and instinctively she reached out to take his right hand in both of hers.  "Ray, it's OK.  Ray, what is it?"  Ray's breathing was labored and his body shuddered.  "I'm glad you're here, I am so glad you're here. Susanna. Just stay with me for a while.  With his free hand he wiped tears from his eyes and looked at her.  "Ray, what's wrong?"  Ray broke off eye contact, looked over her head at the wall.  "I can't tell you what's wrong, Susanna.  I can't."  "I'm so alone, I am so lonely."  He looked at her again.  "I can't tell you how lonesome I am."  He looked down at their hands joined together -- "Do you know it's been four days since anyone has touched me?"  And he sobbed silently, rocking back and forth in his chair looking so wounded, looking so broken, looking like a little lost, abandoned boy.   Susanna's heart was so full of emotion, and she was acting on impulse.  She disengaged her right hand and put her arm around his shoulders holding him with just enough pressure to slow his rocking down.   Look at me, she said to him.  He looked into her eyes.  She said -- You are my Ray of Sunshine.  Remember that."  Then fear flooded through her and she ran out to her car without her coat or purse in a cold and dark mid-December mist.  Her mind was reeling and she tried to recollect herself in the driver's seat.  What had just happened?  What was going on?  She turned the key, the car started.  I need some music she said, and turned on the radio.  Savannah had tuned in last to an 80s station, and the DJ was saying, up next, Dan Fogelberg's top 10 hit from 1981, Same Auld Lang Syne.  Met my old lover in the grocery store. The snow was falling Christmas Eve I stood behind her in the frozen foods. And I touched her on the sleeve.  And then her tears flowed.  And from deep within her, a very, very young voice was crying out over and over again "I want to go home."  "I want to go home" as Dan sang on.   Two minutes later the lyrics pierced her like a spear when Dan was singing She said she'd married her an architect, Who kept her warm and safe and dry, She would've liked to say she loved the man, But she didn't like to lie.  Susanna clawed the driver's door open leaned over and threw up on the asphalt.  She shut the radio off in the middle of the saxophone solo, slammed the transmission into reverse and spun her tires on the wet pavement backing out of there, away from the parish, away from Ray, away from anywhere, just to get away.   I love Brett, Susanna insisted to herself, as she drove.  I love my husband.  I do.  I am faithful to him.  I love my husband.   But another voice, low and soft, almost gentle, said, Yes, you do.  Yes you do.  But are you sure Brett is your husband?  Of course Brett is my husband.  We're married.  We were married on October 10, we made vows to each other.  "Yes, you did.  You did.  You made a vow.  And Brett said the words too.  Maybe Brett made a vow, if he was actually capable of making a vow.  Maybe.  But, Susanna, you know that Brett is on the spectrum don't you?  What's the term Functioning autistic?  He has been since he was little.  Come now, listen to me.  How often does he look at you?  How well does he understand you, really?  Or connect with you emotionally, relationally?  What about how he shrinks from your touch so often?  How he is so, so  introverted?  How he lives so much in a fantasy world in his role playing games with anonymous gamers from all over the world?  Let's be honest, Susanna, about Brett, it's about time.   And let's be honest about you, too.  Why you wanted him for a husband.  Did you want to love him out of charity -- really?  How has that been going, you loving him?  Isn't it true that what you really wanted was your own safety, security, his income?  And isn't it true that you so desperately wanted to not depend on either of your parents, but you weren't ready to stand on your own two feet?   Shut up, shut up, shut up.  Susanna, Don't you know that you actually love Ray?  Are you that blind?  You have loved Ray for months now, but you still you won't admit it.  Didn't you just prove that, holding hands with him, your arm around him?  Your Ray of Sunshine.  Shut up, shut up, shut up! I'm going crazy, Susanna thought.  I am going round the bend.  Could it be that Brett was too impaired to marry me?  Could there be any truth to that?  She remembered several Catholic friends and acquaintances who after their civil divorces had applied for declarations of nullity for their marriages from the Archdiocesan Tribunal.  All of them were granted.   That was a long evening back at home.  Susanna told the kids and Brett she wasn't feeling well, skipped supper and went to bed where she lied awake in the darkness in the chaos of her thoughts.   The next morning she was supposed to meet with Fr. Brownlee and Ray at 9:00-- she considered calling in sick, but she knew she would have to face Ray again at some point.  She arrived at the conference room exactly at 9 -- she didn't want to be late, but she didn't want to be early.  Ray was there, looking like his old self.  He told her Fr. Brownlee is running a little late.  Hey, Susanna, about yesterday -- I'm sorry about being a hot mess.  I'm not usually like that, I know I probably made you uncomfortable.  Susanna found herself saying, no, Ray, it's OK, really, I was glad to help, and taking in his smile.  Thank you, Susanita.  Thank you.  We're OK?  Yes, Ray, we're OK.  OK. I just want to thank you for all you did for me.  You can't possibly know how much you helped me.  You were a gift from God, no really, a gift.  I thank God for you.  You were so attuned to just what I needed.  Can I give you just a little hug, to thank you, my spiritual friend, my sister in Christ?  It's hard for me to express everything that's in my heart for you just in words alone.   And Susanna, speechless, gave the slightest of nods before being enfolded in Ray's arms.  Her body felt electrified as he held her, she felt his body warm and firm and strong against hers, he was smiling down at her, just for those three seconds, and then felt the ache of longing as he let her go, saying, Thank you, mon cherie. Please don't tell anyone how you found me, yesterday.  Let's keep that between us, please, I am still embarrassed by my weakness and vulnerability.   And at that moment, before she could respond Fr. Brownlee's steps sounded in the corridor, and they separately quickly as they heard his customary hearty greeting, his Pax Vobiscum preceding him from the hallway.  They sat down around the table and started with the business items of the day.   After that, their hugs became more frequent and longer.  They prayed together in the chapel.  Sometimes, they furtively held hands, with God's approval, Ray said, as God's beloved children would and siblings who loved each other, Ray said.  But they did hide it, because others wouldn't understand their relationship, as Ray said.   They were having lunch in the break room of the parish center -- instead of at the school cafeteria -- Susanna asked Ray once more what he was crying that late afternoon -- if he felt up to talking about it.  Ray said he was grieving.  Grieving what?  Grieving for himself.  For his situation.  Did you ever see the musical Man of la Mancha?  When Don Quijote sang the Impossible Dream.  She wasn't familiar with the song.  They were alone -- so in a low voice, he sang the first few lines for her.  To dream the impossible dreamTo fight the unbeatable foeTo bear with unbearable sorrowTo run where the brave dare not goTo right, the un-rightable wrongTo love pure and chaste from afar And this was why I was grieving -- I was grieving you.  That all I could do in my love for you, all I could do was to love you, pure and chaste, from afar.  We were never going to be close in the way I wanted, in the way I hoped you wanted, it was just going to be frustration and pain and sacrifice and suffering -- But you Susanna -- you showed me another way -- in that dark hour of despair, you reached out and touched me, took my hand, made it all right.  You had the presence, you were so able to find a way I could not see for us to be together, for us to love each other and it be right and good.  So now it's out there, Susanna Richards.  I, Raimundo de la Cruz, your Ray of Sunshine, I love you.  I will always love you.  Whether you love me or not, I will always love you.  Like in Wendell Berry's novel Jayber Crow -- How Jayber loved Mattie Chatham in the way he did, pure and chaste from afar, because Mattie was married to Troy. Jayber was more faithful and true to Mattie than Troy ever was.  And Ray leaned back and held his arms wide and said.  I love you this big much, mon cherie and laughed.  You don't have to say anything Susanita, it's all right.  I know this is a lot to take in. I'm OK with whatever your decide.  I've decided for me. I've sorted it out on my end, I am at peace.  I've made my commitment.  I will devote my life to you, in love, in whatever way you permit, in whatever way you allow.  I am all yours to take or to leave.  You are my Dulcinea, my querida.   And like a moth to the flame, Susanna was drawn in deeper and deeper.  At the time, the her increasing enmeshment with Ray felt inexorable but later in the clarity of retrospect, she knew it wasn't.  Eventually they had sex on a wrestling mat in storeroom by the school gym.  So much shifted in both of them after that.  For a few weeks after that, they tried to "make the relationship work".  It didn't work.  Two months after his initial conquest of her, Ray's quote eternal love end quote fizzled out.  His idealized Dulcinea image of her faded, and he moved on, decided to leave his ministry position at the parish and moved to another state.   Susanna also quit her job and entered into a deep depression, filled with shame and guilt.  Brett and the kids were worried, they had never seen her like this.  Who am I?  She kept saying to herself.  Who am I?  She was walking downtown that Saturday afternoon on her way from the parking garage to the Catholic bookstore, to find a confirmation gift for her niece as she struggled with her identity.   You know what you are, said the soft, silky voice. You know what you are.  An adulterer.  A whore.   You are Susan.  Not Susanna.  Susanna was the one who resisted seduction, was willing to die rather than enter into adultery.  Don't you remember?  You are not her.  Then hardest cut of all You are just like your father.  You should die. Death will bring you release, Susan, do you know that?  What do you have to live for now? To the be the adulterous wife of Brett who you don't love and who doesn't want you?  To be the whore mother of your children, infecting them with your vice?  Can't you be humble enough, even now, to know that they are better off without you?  End it all now, Susanna.  It would be so easy, there's nothing to it… Approach to the Inmost Cave and the Ordeal At that exact same time on Saturday afternoon, In the little coastal town of Barra Grande, halfway between Rio de Janeiro and Sao Paulo in southeastern Brazil, a 10 year old girl felt an inspiration to pray for whoever might be in most need right now, maybe a lady who was really sad, a lady who needed help.  Her prayer went up to heaven like incense and Susanna did not throw herself into the traffic on that busy street, but made it to the Catholic bookstore, looking a little disheveled.  The cashier noticed her as she came in and gave a faint smile and a halfhearted greeting-- she thought the lady did not look well, but at least she clearly was not one of the homeless people that had been so inconvenient lately.   In her numbness and distress, dwelling on Who am I?  Susanna noticed she was thirsty.  Weird, to notice that right now.  It made sense.  She hadn't had anything to eat or drink all day.  It doesn't matter.  Nothing matters anymore.  She walked up through the aisle on prayer, and a slim green volume caught her eye.  Thirsting for Prayer.  Fr. Jacques Phillipe.  She reaches, takes it off the shelf.   On page 20, she reads "Over and above our sins and failings, we discover that we are God's children. God loves us as we are, with an absolutely unconditional love and it is this love that gives us our deepest identity." Something moved within her. She flipped to page 22 and read: It is a deep aspiration of every man (and, still more, every woman!) to feel uniquely loved. Not loved in a general way, as one of a large group, but appreciated in our uniqueness. This is what the father's love brings about. Each of us can experience that in his eyes we are loved, chosen by God, in an extremely personal way. We often have the feeling that God loves us in a general way: he loves all men, I'm one of them, so he must take a bit of interest in me. But being loved in a " global" way, as one item in the collection, cannot satisfy us. And then to page 23 "Each of us is every right to say: "God loves me as he loves nobody else in the world!" God does not love two people in the same way because it is actually his love that creates her personality, a different personality for each."  And then, for the first time in many months, the sobs came, racking, heaving sobs.  This is who I am.  This is who I am!  This is who I am.  A beloved daughter of God.   The cashier heaved herself out of her chair and peered into the aisle.  Ma'am?  Are you OK? But received no answer from Susanna.  The cashier shrugged and went back to her chair to work on her Sudoku puzzle.  The store manager came over and asked the cashier in a low voice what was going on.  She replied sardonically that he had a major clean up to tend to in aisle 4.   Then Susanna was up on her feet and moving fast to the door. She stopped momentarily to ask the manager and cashier -- is there a Catholic church nearby?  Yes, there's one two blocks north, just go right, and then straight up, can't miss it, Mass is in 50 minutes.  Thank you, thank you and she hurried out -- Ah, do you want to pay for the book?  I'm so sorry, I'm a bit beside myself.  Susanna threw a $20 bill on the counter and ran out.   At St. Patrick's Parish, the new pastor Fr. Jennings was eyeing James, the volunteer guitar player and song leader for the 5:00 PM Mass. James, who he he had inherited with the parish in the reassignment two weeks ago.  James was in his mid-60s, with a grey ponytail, limited musical talent, and a overweening penchant for Marty Haugen tunes, the very ones that Fr. Jennings most despised.  What James lacked in accurate pitch he made up for with increased volume.  And James had not followed through on the music they had agreed on for last week's Mass, substituting songs that seemed to him as better to sing in the moment, ones the congregation was familiar with and loved.  Much better than the dry hymns this new pup of a pastor wanted.  Fr. Jennings told himself to remember that James was also a beloved son of God as he moved in for the confrontation.   But at that moment, a woman burst into the church.  Father, will you hear my confession?  Yes, I would be glad to.  And truth be told, Fr. Jennings appreciated a reprieve from the messy business of dealing with James.   Forgive me father, for I have sinned.  It's been six months or so since my last confession.  And then it all poured out, twelve and a half minutes of heart rending sin and sorrow as Susanna's mascara completed its journey to her chin, borne by tears of both sorrow and joy.  Her hatred for her parents, her pride, the adultery with Ray, it all came out.  And as the priest gave the absolution, the Magdalene smiled.   The Ordeal Susanna left the confessional with three things. A huge sense of relief, a strong sense of mission and a business card for a counselor in the city.  The priest strongly recommended that she see this counselor Sandra, one whom he knew and trusted.  With the suicidal crisis over for now, a whole new set of questions emerged.  How should she tell Brett about Ray?  Should she tell him at all?   The priest had stressed the point that much of her struggle was in the natural realm - in her history, in her upbringing, and that all needed to be addressed.  She needed some professional help.   Susanna looked Sandra up.  Sandra looked young, really young.  She found another one, a Dr. Waldron, a psychologist in his late 60s nearing retirement and started therapy with him.  .  It didn't go well.  She felt blamed and judged by this man who seems more interested in catechizing her than listening.  It lasted two sessions and she fired him.    She connected with Sandra and entered into deep work.  She learned that everyone has parts within them -- constellations of feelings and thoughts and desires.  Sometimes parts blend.   She was able to connect with her managers A Good Girl Part who always wants her to do the right thing and grew exhausted and hopeless when she could not prevent the affair with Ray.   An inner critic who tries to help her by riding her and cutting her down in the hope that she will be good enough to be loved  A stuff-it-down manager who represses other parts out of a deep fear that they will overwhelm her  A keep-it-safe avoiding part that steers clear of potential trouble and works to minimize the risk of being negatively evaluated by others.   And over time she was able to connect with the exiled parts within her A part that wanted to be loved by her father, who so missed her father.  She realized that this part's impulses and desires were fueling so much of her interactions with Ray, because this part saw so much of her father in Ray.  The parts believed that if she were to win Ray's love, it would fill her father needs.   Another exile that felt so much shame about not being able to keep her parents' marriage from falling apart, who felt responsible for the divorce. Her Good Girl part and her inner critic were both focused on silencing this part.  This part just wanted to be able to go home to be loved by Mom and Dad.   A part filled with rage toward her parents and who hated God for giving her those parents  She discovered parts of her that hated her husband and parts of her that were fond of him.  Both could be true.    As parts gave her space, she was able to discover her innermost self -- her innermost self was able to emerge and begin to lead and guide her system, and innermost self with beautiful qualities.   And as she became more integrated inside, her experience of herself began to make sense.  For the first time.   She realized the when she was tempted by the devil, the devil was trying to co-opt the most alienated parts of her, the one who would be most susceptible to his influence.  Then if those parts could take over and drive her bus, great harm would result.   It was painful work.  She felt in her bones what Fr. Jacques Philippe wrote on page 19 of her book:  The negative aspect has to do with her sin, our deep-seated wretchedness. We only know these things truthfully in the light of God. Face-to-face with him, there is no longer any possible room for lies; no invasion, no excuse, no mask. We are compelled to recognize who we are, with their wounds, our weaknesses, or inconsistencies, selfishness, hard-heartedness, secret complicity with evil, and all the rest. But with that work came a sense of peace and joy, of being loved by God and Mary in all her parts.  A realization that all her parts were good. A knowing that her parents did not have to love her any more than they did.  God the Father and Mary her Mother are her primary parents.   Susanna was able to get in touch with Life-Giving Wounds to work through the impact of her parents' divorce in a retreat and in a local chapter.   And she began to pray and related with God and Mary in a completely different way.  Good girl:  I don't have to give up Catholicism.  I just have to give up my flawed understanding of Catholicism.  The Rewards She feared Brett would be devastated when she told him.  He seemed more relieved.  Trevor had told Brett that he thought Mom and Ray had been having an affair.  Trevor had heard rumors and seen some interactions that made him suspicious.  That was a blow to Susanna, that the affair was not nearly so secret as she imagined.   Brett and Susanna were able to find a marital therapist to begin to work on their marriage in a more focused way.  Not easy, there were limitations.   The Road Back She hates her husband and loves him.  Lots of work with the children.  Trevor's anger.    A sense of Providence.   Resurrection / Return Two years later -- she was knocking at the door of her childhood home in Culpeper.  Her father answered, surprised to see her.  It's good to see you -- will you come in?  he asked.  She smiled at him and said:  It's good to see you too, Dad.  And for the first time in more than a quarter century, she meant it.   Take a minute.   Feedback welcome What you thought  Your own story -- send it to me -- crisis@soulsandhearts.com   IIC 102  The Last podcast, episode 100 was a great success in spite of some real technical failure.  We have a learning curve with our technology, and we know some of you were not able to join us.  We have resolved those issues.  We will be meeting on Wednesday, December 14 from 8:00 PM to 9:00 PM Eastern time to record and experiential exercise on parts getting the love that they need. Need to register, here is a link, can get the link from our weekly reflections in your email inbox or in our archive at soulsandhearts.com/blog.   Imagine how Susanna's experience would have been different if she had known about parts before encountering Ray -- or before marrying Brett?  Resilient Catholic Community -- you do not have to be alone.    120 Catholics like you already on board, already on the pilgrimage Reopened December 1 -- new cohort, our St. Dymphna cohort.  Until December 31.  Check it out.  Had a great meeting on December 1 and we will posting the recording very soon if it's not up already.  Sign up soulsandhearts.com/rcc -- lots of information there I've brought together the best Get to know your own parts Get to love your own parts If interested, contact me.   Crisis@soulsandhearts.com 317.567.9594 conversation hours 4:30 PM to 5:30 PM Eastern Time Every Tuesday and Thursday.  (not November 24 which is Thanksgiving).     Upcoming Sign up for the weekly reflection     

On this episode of the What the Floor Podcast, we cover a topic that has been requested multiple times... sound abatement.  What is it? What are IIC and STC ratings? Why do they matter, and how do you test for them?We spoke to an expert in the field, Daniel Mohler from Intertek.  Tune in to hear him explain it all. What the Floor is a T&A Supply Company Inc original production. You can find out more about us at tasupply.com or tasflooring.com. This show is produced by Jose Morales with help from Toni Collier and Jessica Riser. Tell us what you think of the show at wtfpodcast@tasupply.com or #whatthefloorpodcast on social media to let us know what you think.

Orlando Ferreira is the Chief Finance and Administration Officer of IDB Invest, a multilateral development finance institution owned by 47 member countries. 26 members are in the Latin American and Caribbean region where IDB Invest finances projects to advance clean energy, modernize agriculture, strengthen transportation systems, and expand access to financing. In 2021 the multilateral bank issued $1.6 billion in sustainable debt, including a $50 million blue bond for a remediation and preservation project—the first such blue bond in Latin America and the Caribbean. A blue bond is a relatively new form of sustainability bond that is issued to support investments in healthy oceans and marine economies. Orlando is a national of Paraguay. He served as a member of the Board of Executive Directors of the IDB Group from 1999 to 2005, then joined the organization as a Senior Adviser to the CEO in 2006 and later held several Division Chief positions including Chief Operating Officer of the IIC (now IDB Invest), and Chief Strategy Officer for IDB Invest. In this episode we discuss: ✅ What a multilateral development finance institution is ✅ New types of bonds that are supporting the United Nations Sustainable Development Goals (with an interesting example of a Gender Bond IDB Invest issued) ✅ The evolution of measuring social and environmental impact (metrics, metrics, metrics) Key Takeaways: One thing I find remarkable about Orlando (that shows up consistently throughout this conversation) is how humble and transparent he is as a leader. There is no doubt he knows his stuff and is good at what he does, but he doesn't pretend to know it all. Instead, he shares openly lessons learned, areas they are still trying to figure out and improve, and new approaches they're trying to create that might be better. He knows that the path of improvement is never static. There is no finish line we'll finally reach. But instead, the objective is to acknowledge that progress isn't perfect and to humbly strive to improve year after year. These are the leadership traits that create psychological safety, and ultimately the environment for real progress. There are lessons we could all learn from the way multilateral organizations operate. While adopting a mandate to no longer be able to compete wouldn't work in capitalism, consider how the world would be different - how your industry and company would be different - if you had a mandate that the only way to compete in the market is by adding more value. You couldn't launch a new product or business if it didn't add material value to consumers' lives, the planet, or society. Instead of using marketing to create perceived differentiation, what if you were only allowed to create actual differentiation through value creation? Which would actually be a sustainable type of differentiation. Another thing that struck me was the intentional role of knowledge sharing that IDB Invest does. If they realize they aren't the right institution to step in, they provide the knowledge they have to the right institutions. This is a beautiful mix of leveraging both a competitive advantage (which means a condition or circumstance that puts a company in a favorable or superior position) and a collaborative advantage. IDB Invest is recognizing who has the competitive advantage to create real change, and then supporting them through a collaborative knowledge share. What if this type of knowledge sharing was more widespread and intentional? Not just with partners in your own supply chain, but taking accountability to share information that might help institutions that don't make a direct (or even indirect) impact on your business, but could make an impact on society or the world. In business this would mean no longer trapping yourself in purely transactional interactions where you get something in return. Afterall, diverse perspectives spark some of the most innovative ideas. What would it feel like to start sharing outside perspectives regularly and taking pride in helping another organization move in a better direction? An added benefit to adopting this approach is that creativity is a muscle—the more your workforce opens their mind to all creative ideas, the more creative they'll be for your company as well. References: Connect with Orlando on LinkedIn IDB Invest 2022 Sustainable Bond Program: Allocation and Impact Report Banistmo (es) FMO: Entrepreneurial Development Bank SinDesperdicio (es) Connect & Share: If you enjoy the podcast, would you please consider leaving a short review on Apple Podcasts/iTunes? It takes less than 60 seconds, and it really makes a difference in helping to convince hard-to-get guests. I also love reading them! If this episode resonated with you, I ask you to send it to a friend. Help bring even more visibility to these leaders that are using business as a force for good! Subscribe to the Purpose and Profit newsletter to make sure you don't miss future episodes. This podcast is for you, the listener. I'd love to hear what resonated with you, or if you have a suggestion on who would be a great guest for this show. Please send me a note at info@KathyVarol.com.

Summary -- It is so common for Catholics (and others) to reject the love of God, to not let that love in.  Join Dr. Peter for this episode where we explore in depth the eight natural, human formation reasons why we refuse God's love. We also look at what Hell really is and why it really exists.  Through examples, quotes, and an exploration of Dr. Peter's own parts, listen to how this critical, central topic comes alive.  And then Dr. Peter presents the an action plan for accepting and embracing God's love.   Lead-in “It's very hard for most of us to tolerate being loved.” ―Psychiatrist and Harvard Professor  George Vaillant (need description)  The Hardest Thing about love for many of us Catholics -- is to be loved.  To tolerate being loved first.  We can't love unless we take love in first.  We can't generate love out of nothing on our own, we don't have that power.     Many Catholics make sacrifices great and small in an attempt to love others.   Many Catholics go to great lengths to try to please God and to love their neighbor -- very busy people, most parishes have a few of these -- always volunteering, working, making things happen, St. Vincent de Paul, soup kitchens, corporal works of mercy -- working so hard to live out the Gospel as they understand it, but it's all external -- they are very out of touch with their internal lives.  Their prayer lives are shallow and sketchy and they are uncomfortable in their own skin and they will not tolerate silence.   The vast majority of us Catholics will not tolerate being loved deeply or fully.  We shy away from receiving love.  We get so uncomfortable, we skirt around the edges of being loved Or we allow love into us only so far.  Only so far.  We won't let real love permeate all of our being.  We let the quote acceptable unquote parts of us be loved, those parts we allow in our shop window.  Those parts we believe others will accept.   But to allow someone to love all of you -- your nasty parts, your shameful parts, your disgusting parts, your hidden leper parts, your sinful parts -- those tax collector parts, your inner prostitutes and blasphemers, your Pharisee parts, the parts of you that are so lost and so isolated and so angry and hateful?  Those parts?  Most of us will say -- No way -- no way does anyone get to see those parts if I can help it, let alone love those parts.  How about your terrified parts, your desperate parts, your wounded, traumatized parts, the ones no one wants, the parts of you that have been rejected by everybody, including yourself.  This podcast is for us Catholics who understand at least intellectually that we have those parts.  And that those parts need to be loved.  Those parts also need to be redeemed.   For anyone out there who is saying "Well, I don't think I have any parts like that, Dr. Peter. I don't have any problems being loved."  My response to that is one of two possibilities -- either you are: 1 -- A very special person, who has been freed from our fallen human condition and you've achieved an extraordinary degree of perfection in the natural and spiritual realms -- and if so, congratulations to you.  You don't need this podcast and you don't need this episode, you are so far above the rest of us.  I'm in awe of you.  You don't need what I have to offer.   Or 2 -- you don't know yourself very well.  You are out of touch with yourself and your parts, disconnected inside.   It's especially hard for us to tolerate being loved by God.  That's the primary reason we don't love God back and we don't love our neighbor and we don't love ourselves. We won't be loved first.  God loved us first.   It all starts with God's love -- not our love.  God loved us first.   Heisman Trophy Winner Tim Tebow in his Book Shaken  “We were created by Love, in love, and for love.”   Paul tells us in Romans 5:8  But God shows his love for us in that while we were yet sinners Christ died for us.    God loved us first.   1 John 3:1 See what love the Father has given us, that we should be called children of God; and so we are. The reason why the world does not know us is that it did not know him. The world does not know God.  Christianity is the way to discover who God actually is.  To discover what Love actually is.   John tells us in 1 John 4:9-10 In this the love of God was made manifest among us, that God sent his only Son into the world, so that we might live through him. In this is love, not that we loved God but that he loved us and sent his Son to be the expiation for our sins.  This is what I want you to remember.  From St. John, 1 John 4:19:  St. John tells us:  We love because he first loved us  And it's up to us to take that love in, to let it reach to every corner of our being.  That doesn't sound easy.  And it's not as easy as it sounds.    Intro I am Dr. Peter Malinoski, a.k.a. Dr. Peter, clinical psychologist, trauma therapist, podcaster, blogger, cofounder and president of Souls and Hearts -- but most of all I am a beloved little son of God, a passionate Catholic who wants to help you to experience the height and depth and breadth and warmth and the light of the love of God, especially God the Father and our primary Mother Mary. What I want for you more than anything else is that you enter into a deep, intimate, personal, loving relationship with the three Persons of the Trinity and with our Lady. That is what this Interior Integration for Catholics podcast is all about, that is what Souls and Hearts is all about – all about shoring up the natural foundation for the spiritual life of intimacy with God, all about overcoming the natural human formation deficits and obstacles to contemplative union with God our Father and our Lady, our Mother  We are on an adventure of love together. Episode 94 of this podcast focused on the primacy of love in the Catholic life. Episode 95 focused on trauma's devastating impact on our capacity to love. Episode 96 discussed how trauma hardens us against being loved. Episode 97 discussed how trauma predisposes us to self-hatred and indifference, a refusal to love ourselves.  And episode 98, the last episode was all about ordered self-love, how we need to love ourselves in an ordered way in order to love God and neighbor, to carry out the two great Commandments. Today were to take a step back were to look at the most critical prerequisite for loving God and others. We are going to discuss being loved the first, accepting the love of God first. This is absolutely essential. The most critical mistake that most Catholics make is to refuse the love of God. Let me say that again.  The most critical mistake, the most devastating, catastrophic mistake that most Catholics make is to refuse to allow God's love to transform us entirely, to make us into new men and women.  Let us start out with The order of Loves God leads with love -- he goes first.  God makes the first move.  He moves toward us, we who He created, and who have fallen from grace because of original sin.  We don't make the first move.  God does.  He loved us first, and he continues to love us first  Sean Mitchell -- We Love Because He First Loved Us -- Those Catholic Men.   “We love because he first loved us” (1 John 4:19).  These words from the first letter of John beautifully and succinctly sum up the origin and end of the Christian life—which, in a word, is love.  “Being Christian,” said Benedict XVI, “is…the encounter with an event, a person, which gives life a new horizon and a decisive direction” (Benedict XVI, Deus Caritas Est, 1).  That “encounter” is our experience of God “first loving us.”  The “new horizon” that it opens up, the “decisive direction” that it gives to our lives, is love—our love of God and our neighbor because of His prior love of us.  To participate in that endless exchange of love is what it means to be a Christian.  It is the center from which all other aspects of the Christian life emanate.  I fear that a significant number of Catholic men miss this point and regard something other than love as the central point of being a follower of Christ. What I did not include from Benedict's quote above is what he says being Christian is not.  It is not, he says, “the result of an ethical choice or a lofty idea” (Benedict XVI, Deus Caritas Est).  To state that more generally, being Christian isn't primarily about my will or my intellect and what I do with them (i.e., make “ethical choices” and assent to “lofty ideas”).  Rather, it is first and foremost about my heart, my whole person in all its mystery, and what has been done to it by God.  Is it not the case, though, that so many of us fail to understand this?  If we're honest with ourselves, I think we would have to admit that it is, that we ourselves are among those men who place something other than love at (or at least close to) the center of our “Christian” life…even if we don't realize it. Comment on this Edward Vacek:  Love, Human and Divine: The Heart of Christian Ethics.  The sequence in loving and being loved.    (1) God affirms us; (2) God receives us; (3) we accept God's love; (4) we affirm God; (5) God forms community with us; (6) we cooperate with God in loving God in the world; and finally (7) we grow in a limited co-responsibility with God. p. 177 Genesis 3.   The trauma of original sin.   God comes looking for them -- God seeks them out -- hiding, fleeing from him in their shame and confusion and bitterness, in the trauma of original sin.   God calls out to them -- example of His gentleness.   No cursing of Adam and Eve.  The serpent is cursed, the ground is cursed.  Not Adam and Eve Provides clothing for them to help them with their shame.   Protects them from the Tree of Life.  Banishing them from the garden was an act of love -- if they had eaten from the tree of life, the Genesis 3:22- 24 Then the Lord God said, “Behold, the man has become like one of us, knowing good and evil; and now, lest he put forth his hand and take also of the tree of life, and eat, and live forever”—  therefore the Lord God sent him forth from the garden of Eden, to till the ground from which he was taken. 24 He drove out the man; and at the east of the garden of Eden he placed the cherubim, and a flaming sword which turned every way, to guard the way to the tree of life.  God making sure that they won't be separated from Him forever. St. Ephrem the Syrian, Commentary on Genesis, 122 explains, “God did this lest this life-giving gift that they would receive through the tree of life become misery, and thus bring worse evil upon them than what they had already obtained from the tree of knowledge.  From the latter tree they obtained temporal pains, whereas the former tree would have made those pains eternal.  From the latter they obtained death which would have cast off from them the bonds of their pains.  The former tree, however, would have caused them to live as if buried alive, leaving them to be tortured eternally by their pains.”   The basic problem with the sequence -- not tolerating enough contact with God  to be affirmed, for Him to receive us. to understand Him in a radically different way.   And what kind of love is God's love for us?  God Himself tells us:  I have loved you with an everlasting love; therefore I have continued my faithfulness to you. Jeremiah 31:3.  God is faithful to us.  He loves with an everlasting love.  Isaiah 54.10  For the mountains may depart     and the hills be removed,but my steadfast love shall not depart from you,    and my covenant of peace shall not be removed,    says the Lord, who has compassion on you. How steadfast is God's love:  Deuteronomy 7:9 tells us.  Know therefore that the Lord your God is God, the faithful God who keeps covenant and steadfast love with those who love him and keep his commandments, to a thousand generations Psalm 86:5 For thou, O Lord, art good and forgiving, abounding in steadfast love to all who call on thee. God requires a response from us.  -- abounding in steadfast love to all who call on thee.  We have to call on him, we have to respond to the love.   That is what this episode is all about.  This is episode 99 of the Interior Integration for Catholic podcast, released on November 7, 2022 titled IIC 99 Why We Catholics Reject God's Love for Us and How to Embrace that Love  CCC 221 But St. John goes even further when he affirms that "God is love": [1 John 4:8, 16] God's very being is love. By sending his only Son and the Spirit of Love in the fullness of time, God has revealed his innermost secret: God himself is an eternal exchange of love, Father, Son and Holy Spirit, and he has destined us to share in that exchange.  We have to take him up on that.   How do we know we are loved by God? -- 2 ways.   Faith and lived experience Faith  Infused virtue  CCC 150   Faith is first of all a personal adherence of man to God. At the same time, and inseparably, it is a free assent to the whole truth that God has revealed. As personal adherence to God and assent to his truth, Christian faith differs from our faith in any human person. It is right and just to entrust oneself wholly to God and to believe absolutely what he says. It would be futile and false to place such faith in a creature. CCC 153  When St. Peter confessed that Jesus is the Christ, the Son of the living God, Jesus declared to him that this revelation did not come "from flesh and blood", but from "my Father who is in heaven".24 Faith is a gift of God, a supernatural virtue infused by him. "Before this faith can be exercised, man must have the grace of God to move and assist him; he must have the interior helps of the Holy Spirit, who moves the heart and converts it to God, who opens the eyes of the mind and 'makes it easy for all to accept and believe the truth.'"25  Lived experience of the relationship with God.   2 Timothy 1:12 But I am not ashamed, for I know whom I have believed, and I am sure that he is able to guard until that Day what has been entrusted to me. Can feel it in consolations.   We don't want to engineer emotional experiences of closeness, manipulating emotions -- Concern about Catholic youth events, hyper emotional, noisy and using psychological techniques of influence to generated contrived emotional  experiences.  Hyping people up, getting them out of their window of tolerance.   We don't want to rely on our subjective experience of lived relationship Because the subjective experience of connection with God can vary way too much.   Von Hildebrand writes, “Our confidence in God must be independent of whether we experience His nearness, whether we sense the enlivening touch of grace, whether we feel ourselves being born on the wings of His love.” (p 210).  Mother Teresa 1957 confided to spiritual director:  In the darkness . . . Lord, my God, who am I that you should forsake me?  The child of your love — and now become as the most hated one. The one — you have thrown away as unwanted — unloved. I call, I cling, I want, and there is no one to answer . . . Where I try to raise my thoughts to heaven, there is such convicting emptiness that those very thoughts return like sharp knives and hurt my very soul.  Love — the word — it brings nothing.  I am told God lives in me — and yet the reality of darkness and coldness and emptiness is so great that nothing touches my soul.  David Scott in chapter 17 of his book The Love That Made Mother Teresa wrote:  For more than fifty years following her initial visions and locutions, Mother Teresa was wrapped in a dark, pitiless silence. She only once more heard the voice of God, and she believed the doors of heaven had been closed and bolted against her. The more she longed for some sign of his presence, the more empty and desolate she became.   Needs Weekly Reflection:  from September 6, 2022:  The Top 10 Needs That Fuel Modern-Day Idol Worship  go to soulsandhearts.com/blog   Integrity Needs My need to exist and survive  My need to matter  My need to have agency  My need to be good  My need for mission and purpose in life   Attachment needs  --Brown and Elliott (2016) Felt sense of safety and protection -- have to go through the valley of shame, fear, anger, grief  Feeling seen, heard, known and understood -- have to tolerating being in relationship, being present.   Feeling comforted, soothed and reassured  Feeling cherished, treasured, delighted in  Feeling the other has your best interests at heart   Resistance to being loved Weaving in Integrity needs and attachment needs.   Main themes Limited vision and lack of imagination, leading to a refusal to be transformed by God  We don't understand God's love  The Costs of Being Loved by God  Poor God images  Poor Self images -- Shame  Refusal to be vulnerable, to be exposed, to be revealed to God.  Lack of courage.  Anger at God -- rebellion   Limited vision and lack of imagination, leading to a refusal to be transformed by God -- unhealthy satisfaction in far more limited spiritual goals -- a willingness to settle.  Von Hildebrand According to von Hildebrand, the vision of most Catholics is way too narrow – our sights are set way too low. We are satisfied with too little in the spiritual life – we are like chickens pecking at the ground when we are called to soar as eagles.  We may be content with merely avoiding sin, overcoming vices and developing virtues. Some of us may pursue the spiritual life as a self-improvement project, satisfied with incremental gains  Weekly reflection October 26, 2022 -- Why we resist change – and especially radical transformation.  Ransom Riggs Miss Peregrine's Home for Peculiar Children character Jacob Portman “One day my mother sat me down and explained that I couldn't become an explorer because everything in the world had already been discovered." Love, in some sense, is nothing other than an invitation to great joy and suffering, so they shy away from it.  Paul Catalanotto Refusal to love is also refusal to live  The Catholic Weekly John 6: 41-42 The Jews then murmured at him, because he said, “I am the bread which came down from heaven.” They said, “Is not this Jesus, the son of Joseph, whose father and mother we know? How does he now say, ‘I have come down from heaven'?”  John 6: vs. 60 and 66  Many of his disciples, when they heard it, said, “This is a hard saying; who can listen to it?” After this many of his disciples drew back and no longer went about with him. We don't understand God's love Isaiah 55:8-9  For my thoughts are not your thoughts, neither are your ways my ways, says the Lord. For as the heavens are higher than the earth, so are my ways higher than your ways and my thoughts than your thoughts.  Sharon Jaynes When Love Hurts April 17, 2018.  Proverbs31.org   “Mommy, Mommy,” Steven cried. “Don't let them hurt me!”My son, Steven, was about 3 years old when he contracted a severe case of the flu. His slumped body snuggled listlessly like an old, worn rag doll.When I carried him into the medical clinic, the doctor quickly diagnosed dehydration and immediately sent us to the hospital.My heart ripped apart as the nurses strapped my little boy onto a table and began placing IVs in his tiny arms.“Mommy, Mommy,” Steven cried. “Make them stop! They're hurting me.”“No, honey,” I tried to assure him. “They're going to make you all better.”“Mommy, help me!”Steven cried. I cried. The nurses cried.I could only imagine what was going through Steven's little mind. Why are these people hurting me? Why doesn't Mommy make them stop? She must not love me. She's not protecting me. If she loved me she wouldn't let them do this. She must not care about me.Standing in the corner watching my little boy cry, I wondered if that's how God feels when I'm going through a painful situation that's for my ultimate good. I cried out, “God, why are You letting this happen? Don't You love me? Don't You care about what's happening to me? Why don't You make it stop?” Can see the need to exist here being threatened.  I might be very injured, I might die.  Integrity need No felt sense of being protected -- attachment need.  In fact, just the opposite.  The little child was being protected, but didn't understand, didn't feel it.   No felt sense of being comforted or soothed, child not open to it.  Third primary condition of secure attachment No felt sense of support for his highest good.  Fifth condition of secure attachment.   Parts of us very young, like this 3-year-old.   Hebrews 12:11  For the moment all discipline seems painful rather than pleasant; later it yields the peaceful fruit of righteousness to those who have been trained by it.  Poor view of discipline Bad experiences of being disciplined -- not having been disciplined out of love  But rather out of anger or inconvenience or frustration.   Freud -- gratification and frustration to grow.   The Costs of Being Loved by God  Real love, agape or charity, is always given freely -- we understand that much But real love, agape, charity -- real love is never received freely in this fallen world.  There is a cost to allowing real love into our lives.   Very little discussion about the costs of being loved by God.  I find that so strange.  So many Catholics don't think this way. It is as though Catholics have parts that believe that being loved by God is one of two things Being loved by God should easy, delightful, peaceful --  like being the lead character a Hallmark movie  Romance novels.  Easy love that just come naturally.    Emotional Junk food that nourishes illusions.   and when it's not, they conclude that God isn't loving them, or that they are excluded from His love Being loved by God is terrible Echoes of Hebrews 10:31    It is a fearful thing to fall into the hands of the living God.   Burning away Real love -- Agape -- burns away things that are sinful within us -- it doesn't coexist with the vice within us.  Real love also purifies us from anything that is not morally wrote, but that is disordered or dysfunctional or imperfect  Real love is the greatest good.  And because it's the greatest good, it requires us to give up lesser goods.  Perceived good and actual goods.   Coping strategies, crutches that helped us in the past Analogy of the safe -- limited room, silver and gold.  1 Peter 1:7 So that the tested genuineness of your faith—more precious than gold that perishes though it is tested by fire—may be found to result in praise and glory and honor at the revelation of Jesus Christ.  Isaiah 48:10 Behold, I have refined you, but not as silver; I have tried you in the furnace of affliction.   Zechariah 13:9 And I will put this third into the fire, and refine them as one refines silver, and test them as gold is tested. They will call upon my name, and I will answer them. I will say, ‘They are my people'; and they will say, ‘The Lord is my God.'”  Proverbs 17:3  The crucible is for silver, and the furnace is for gold, and the Lord tests hearts.  Job 23:10 But he knows the way that I take; when he has tried me, I shall come out as gold.  Integrity needs I exist  I matter  I am good   Attachment needs Felt safety and protection  Felt comfort and reassurance  Felt sense of being cherished and delighted in.  No experience of that while being corrected, perfected.   xThe cost is up front -- the benefit in the future.   Poor God images We don't understand God.  We don't know who he is. -- reflected in the Sharon Jaynes' story of her son at the doctor's office.    Lack of confidence in God.  Lack of Faith   God Images =  My emotional and subjective experiences of God, who I feel God to be in the moment.  May or may not correspond to who God really is.  What I feel about God in my bones. This is my experiential sense how my feelings and how my heart interpret God. Each part, not in right relationship with the innermost self, has a distorted God image.   God images are often unconscious.     Initially God images are shaped by the relationship that I have with my parents.     My God images are heavily influenced by psychological factors  Different God images can be activated at different times, depending on my emotional states and what psychological mode I am in at a given time.   God images are always formed experientially; God images flow from our relational experiences and  Also how we construe and make sense of those images when we are very young.  My God images can be radically different than my God concept.  We all have heretical God images.   Differ from  God Concept  = What I profess about God.  It is my more intellectual understanding of God, based on what one has been taught, but also based on what I have explored through reading.  I decide to believe in my God concept.  Reflected in the Creed, expanded in the Catechism, formal teaching.   Can take a while to get to these God images -- not on the surface  We don't know God very well.   We refuse Mother Angelica's Little Book of Life Lessons And Everyday Spirituality :  Allow people to love you as they must love you, not as you want them to love you. Even God does not love us as we wish Him to. Learning to love is learning to accept love as it comes. I will lose the relationship with God that I have if I push the envelope And you will.  That is true.   Episodes 37-49 on God images.   Really hits on attachment needs.   Poor Self images -- Shame Self-images are much more emotionally driven, much more intuitive, subjective, and they vary a lot more from moment to moment.     Each part, not in right relationship with the innermost self, has a distorted self image.   Pastor Jonathan Edwards  Sinners in the Hand of an angry God, 1740s    “The God that holds you over the pit of hell, much as one holds a spider or some loathsome insect over the fire, abhors you, and is dreadfully provoked; his wrath towards you burns like fire; he looks upon you as worthy of nothing else, but to be cast into the fire ... you are ten thousand times so abominable in his eyes, as the most hateful and venomous serpent is in ours.”  Hiding from God.  Genesis 3.   I don't want to find out I am unlovable.  I can't bear that.   Episode 24 of this podcast, God images and self images.  Really hits on integrity needs.  Especially the need to be good.   Refusal to be vulnerable, to be exposed, to be revealed to God.  Because for love to be real, for love to be agape means me allowing you to love all of me.  All my parts.  My entire being Not just the acceptable parts of me in the shop window, those that I allow others to see.   Fears of being hurt one more time -- Fears of betrayal  Fears of abandonment   We think we can hide.   Self protection -- need to survive.  Need to be good.  Lack of courage. Philophobia -- fear of love  All of us have parts that fear love.  Comfort in the familiarity of the dysfunction we know.   Predictability Change is scary  Maureen Brady, Beyond Survival: A Writing Journey for Healing Childhood Sexual Abuse “For change to occur in us, we must be willing to enter the wilderness of the unknown and to wander in unfamiliar territory, directionless and often in the darkness....We do not need to keep every little thing under control. In fact, we find ourselves only by allowing some falling apart to happen.” Erica Jong:  I have accepted fear as a part of life - specifically the fear of change... I have gone ahead despite the pounding in the heart that says: turn back. Nelson Mandela:  I learned that courage was not the absence of fear, but the triumph over it. The brave man is not he who does not feel afraid, but he who conquers that fear. Anger at God, Rebellion against Him. secondary to poor God images.  Anger is the ordered emotion in response to injustice.   What is a part?  Separate, independently operating personalities within us, each with own unique prominent needs, roles in our lives, emotions, body sensations, guiding beliefs and assumptions, typical thoughts, intentions, desires, attitudes, impulses, interpersonal style, and world view.  Each part also has an image of God.   When parts are not integrated, under the leadership and guidance of my innermost self Self:  The core of the person, the center of the person.  This is who we sense ourselves to be in our best moments, and when our self is free, and unblended with any of our parts, it governs our whole being as an active, compassionate leader.   Parts in greater detail -- discussed my parts in Episode 71 A New and Better Way of Understanding Myself and Others.   Good Boy Evaluator (formerly "the Critic") Melancholio Adventurer (formerly my "part who holds fear") Feisty One (formerly my "angry part") Challenger (formerly "the Rebel") Lover Part Collaborator Parts (formerly my Competent Part) Guardian (formerly "the Intimidator") Creative Part Consequences -- Hell Nothing can separate us from God's love.   Romans 8:38-39 For I am sure that neither death, nor life, nor angels, nor principalities, nor things present, nor things to come, nor powers, 39 nor height, nor depth, nor anything else in all creation, will be able to separate us from the love of God in Christ Jesus our Lord. Nothing can separate you from the love of God, not even demons -- angel and principalities.  Nothing can separate you from the love of God.  With one exception.  You.   Only you can separate you from the love of God.  Only you have the power to do that, by refusing to let that love come it. That's what sin is.  It's separating ourselves from God.  Sin is damaging our relationship with God.    Separation happens  Jesus weeping over Jerusalem Luke 19:41-44  And when he drew near and saw the city he wept over it, saying, “Would that even today you knew the things that make for peace! But now they are hid from your eyes. For the days shall come upon you, when your enemies will cast up a bank about you and surround you, and hem you in on every side,  and dash you to the ground, you and your children within you, and they will not leave one stone upon another in you; because you did not know the time of your visitation. It's not that God won't protect Jerusalem.  It's that he could not protect the Israelites, not without violating their freedom, not without forcing Himself on them.   Matthew 7:13-14   “Enter by the narrow gate; for the gate is wide and the way is easy, that leads to destruction, and those who enter by it are many.  For the gate is narrow and the way is hard, that leads to life, and those who find it are few. Pope John Paul II  in a 1999 audience, God did not create Hell.  Hell  “… is not a punishment imposed externally by God but a development of premises already set by people in this life.” Catechism of the Catholic Church edited by Archbishop Rino Fisichella 2019 by Our Sunday Visitor Louis Ladaria:  To be precise, God did not make Hell.  His free creatures make it, inasmuch as they separate themselves from Him. Nor does God send anyone to Hell: it is the damned one who separates himself and does not want to enter into the Father's house. God, St. Irenaeus said, does not really look to punish the damned, but as they are deprived of all good things, it is the penalty that pursues them (Adversus Haereses, V. 27, 2; a similar idea in St. Augustine, Enarrationes in Psalmos, 5, 10: God abandons the sinner to his evil, he does not, properly speaking, give evil to anyone). Because of this, and despite what is said sometimes, we need to insist on the fact that Hell does not say anything against the infinite goodness of God. (p. 863).  Dean Koontz: The Book of Counted Sorrows:  “We make Hell real; we stoke its fires. // And in its flames our hope expires.   CCC 30 Although man can forget God or reject him, He never ceases to call every man to seek him, so as to find life and happiness. CCC 1037  God predestines no one to go to hell; for this, a willful turning away from God (a mortal sin) is necessary, and persistence in it until the end. In the Eucharistic liturgy and in the daily prayers of her faithful, the Church implores the mercy of God, who does not want "any to perish, but all to come to repentance. Not trying to catch us, not with a hand on the trap door to hell.   Fr. Edward McIlmail, LC  “Ask a Priest: If God loves us so much, why does hell exist?”  An analogy might help. Imagine you are on a ship that is searching for survivors from a sunken ocean liner. You see a passenger struggling in the waves behind you. You throw a lifeline to him, but he refuses to grab it. You beg him to take hold of the lifeline, but he ignores your plea. Eventually, he sinks below the waves and drowns. Does his drowning indicate that you were indifferent? When you begged him to grab the lifeline, were you displaying hate? Was his drowning your fault?  The answer to all these questions is: no. The person in the water, for whatever reason, refused your help. His drowning was the consequence. It doesn't matter why we flee from God and why we flee from His love.   Hell as isolation -- cut off from everyone.   Images of hell   Hell as isolation Tekla Babyak in 2018 article Dante, Liszt and the alienated agon of hell writes:  Dante Alighieri's Inferno portrays Hell as an alienated realm in which the doomed spirits must spend eternity in isolation and regret.  Deepest level of hell, the ninth circle:    "The treacheries of these souls were denials of love (which is God) and of all human warmth. Only the remorseless dead center of the ice will serve to express their natures. As they denied God's love, so are they furthest removed from the light and warmth of His Sun. As they denied all human ties, so are they bound only by the unyielding ice." John Ciardi, Inferno, notes on Canto XXXII, p. 248 Satan encased waist deep in ice.  Not fire.   Celeste Ng  Little Fires Everywhere character of Mia Warren “In all her years of itinerant living, Mia had developed one rule: Don't get attached to any place, to any apartment, to anything. To anyone.”   In Hell on earth Fragmentation of Dante's inferno -- lived now.   Dietrich Bonhoeffer  Life Together  “Sin demands to have a man by himself. It withdraws him from the community. The more isolated a person is, the more destructive will be the power of sin over him, and the more deeply he comes involved in it, the more disastrous his isolation.”  Sharon M. Draper  Out of My Mind  character Melody Brooks  “It's like I live in a cage with no door and no key. And I have no way to tell someone how to get me out.”  Sue Johnson Hold Me Tight   “Isolation and the potential loss of loving connection is coded by the human brain into a primal panic response.”  C.S. Lewis:  The Great Divorce:  “That is why, at the end of all things, when the sun rises here and the twilight turns to blackness down there, the Blessed will say, “we have never lived anywhere except in heaven,' and the Lost, “We were always in Hell.” And both will speak truly.”   Action Plan  Pray Set aside the time.  First thing  Personal Prayer: A Guide for Receiving the Fathers' Love Fr. Thomas Acklin and Fr. Boniface Hicks.  Benedictines, very wise, good grasp of psychology.   Prayer Primer or Fire Within Fr. Thomas Dubay   Read the first letter of John. Lectio Divina Dan Burke Spiritual Direction.com Lectio Divina, A Guide: What it is & How It helps Prayer Life  Appendix on Lectio Divina in Fr. Jacques Philippe's book Called to Life  Section on Lectio Divina titled "mediating on Scripture in Fr. Jacques Philippe's book Thirsting for Prayer   Nike Model -- just do it.  Set aside perfectionism, desire to do it well. You're not going to do it well.  You're going to do it badly.   The most important things in life we either do badly or we don't do at all.   St. Therese of Avila. says: “He who neglects mental prayer needs not a devil to carry him to hell, but he brings himself there with his own hands.”   St. John of the Cross says: “Without the aid of mental prayer, the soul cannot triumph over the forces of the demon.”  St. Teresa of Avila “Prayer is an exercise of love.” (Life 7:12)   Do your human formation work Relational spirituality -- about relationship  Any difficulties you have in relationships in the natural realm, here on earth -- you are going to bring into your spiritual relationships.   Interior integration  Why is interior integration crucial for union with God?  Weekly reflection October 12, 2022  soulsandhearts.com/blog.   Get to know your parts Reason for not praying   Jay Earley -- Self Therapy Vol. 1.  Now in the Third Edition.    Bonnie Weiss Self-Therapy Workbook.   Means Therapy or counseling -- especially Internal Family Systems therapy with a therapist who is Catholic or who at least respects your Catholic Faith and will not undermine it.   Experiential Exercise -- November 21.  Splitting those out.   Resilient Catholic Community -- you do not have to be alone.   Reopening December 1 -- new cohort Get to know your parts I've brought together the best Wait list -- email on November 10.  Sign up soulsandhearts.com/rcc If interested, contact me.   Crisis@soulsandhearts.com 317.567.9594 conversation hours 4:30 PM to 5:30 PM Eastern Time Every Tuesday and Thursday.  (not November 17 -- online conference).   Pray for me  Sent the word out.  Let people know about our offerings at Souls and Hearts, this podcast, the weekly reflections.  Sign up for those - email.  Can see the archive at soulsandhearts.com/blog   Patroness and Patron  

On the 15th edition of DITD Bites, we get into the world of morals & ethics in Journalism and a special conversation of wider media and the response to the death of The Queen.TIMESTAMPS:Weekly Music Roundup - (1:55) (Ben = Bold / Charlie = Italics) Yeat - Lyfe NAV - Demons protected by Angels YoungBoy - Realer 2 38 Spesh - 7 Shots Black Soprano Family - Long Live DJ Shay Cappadonna x Stu Bangas - 3rd Chamber Grail Bars Semiratruth & JWords - loading... A-F-R-O - Beatz From Da FRO Vault (Vol. II) C.S. Armstrong - THE DAMASCUS LP Ari Lennox - Away Message Ari Lennox - age/sex/location Sampa The Great - As Above, So Below Exploitative Journalism - (20:34)The Queen - (43:43) Lighter Note - (1:13:53) Thanks for listening. Below are the Social accounts for all parties involved. Be sure to let us know that you're supporting us!Music - "Pizza And Video Games" by Bonus Points (Thanks to Chillhop Music for the right to use)HHBTN (Twitter & IG) - @HipHopNumbers5E (Twitter & IG) - @The5thElementUK5E Community DiscordChillHop (Twitter) - @ChillhopdotcomBonus Points (Twitter) - @BonusPoints92Other Podcasts Under The 5EPN:"What's Good?" W/ Charlie TaylorIn Search of SauceBlack Women Watch...5EPN RadioThe Beauty Of Independence

  Summary:  Real love (agape) is given freely -- but it is not received freely in our fallen human condition.  Join me in this episode as we discuss the costs of opening our hearts to loveand the price of being loved fully, of being loved completely, in all of our parts.  We review why so many people refuse to be loved -- and we examine the psychological and human formation reasons for turning away from love.  Finally we discuss what we can do to get over our natural-level impediments to receiving love.   Lead-in  I am a rock I am an island I've built wallsA fortress deep and mightyThat none may penetrateI have no need of friendship -- friendship causes painIt's laughter and it's loving I disdainI am a rock I am an island I am a rock -- Paul Simon wrote it in 1965 and Simon and Garfunkel  Released it as a single in 1966, and it rose to #3 on the charts -- why because it resonated with people.  It was popular because it spoke out loud what many people's parts feel.   The desire to become a rock, the impulse to build the walls, to keep everyone out, to repudiate love and laughter, to not need anything or anyone.    Kate McGahan -- untitled poem   I don't need anyone, I said.Then you cameI need I need! I NEED YOU. I needed you.What did you teach me?Not to need you.NOT TO NEED. -  I don't want to be in love, anymore. I just want to be left alone. And no, I am not depressed or something. No suicide is happening here... I am fine. Trust me. Sharmajiassamwale So you want love.  But you also don't want love.  But you want love.  But you don't.  You do.  You don't.  You're conflicted.  How do you understand this conflict within you?  Can you and I understand this push-pull, this attraction - avoidance, this Yes and No within us more clearly.  Yes we can.  And we must.  Or we will wind up always skating along the edge of love, never really entering in.  And there are consequences for that -- and no one put it more succinctly than the English poet and playwright Robert Browning, who said: “Without love, our earth is a tomb”   Intro We do want to be loved, but we don't.  Why?  Because we want the benefits of love, but we don't want the costs   The Benefits To love and be loved is to feel the sun from both sides.  David Viscott  If you don't have that memory of being loved, you are condemned to search the world for something to fill you up. -- Michael Jackson The costs.  Real love is given freely, but it is not received freely in this fallen world.   Almost no one talks about the costs of being loved.  I find that so strange.  People don't think this way.  There are costs to receiving love, to accepting love, to allowing love in to our hearts.   It's painful to be loved in this fallen world.  this is not well understood by many people, especially those who are not in touch with trauma, or who haven't suffered as much as others Bernard Brady's 2003 book "Christian Love: How Christians Through the Ages have Understood Love  Second sentence of the book, in the preface:  "Loving seems entirely natural and being loved seems wonderfully good." Not to many people RCC member -- so glad you can discuss tolerating being loved.     Real love -- Agape -- burns away things that are sinful within us -- it doesn't coexist with the vice within us. Bernard Brady: Christian Love, p. 16:  "…love transforms those who love and those who are loved."   Every true love and friendship is a story of unexpected transformation. If we are the same person before and after we loved, that means we haven't loved enough.”   ― Elif Shafak, The Forty Rules of Love Change is scary “Taking a new step, uttering a new word, is what people fear most.”― Fyodor Dostoevsky, Crime and Punishment    Real love also purifies us from anything that is not morally wrote, but that is disordered or dysfunctional or imperfect Real love is the greatest good.  And because it's the greatest good, it requires us to give up lesser goods.  Perceived good and actual goods.   Coping strategies, crutches that helped us in the past Analogy of the safe -- limited room, silver and gold.  Vulnerability I will lose what I have I will lose to possibility of being loved in the future I don't want to find out I am unlovable.  I can't bear that.    Because for love to be real, for love to be agape means me allowing you to love all of me.  All my parts.  My entire being Not just the acceptable parts of me in the shop window, those that I allow others to see.   The greatness of the adventure of loving can be intimidating Love, in some sense, is nothing other than an invitation to great joy and suffering, so they shy away from it.  Paul Catalanotto Refusal to love is also refusal to live  The Catholic Weekly  Dietrich von Hildrebrand those who "wish to linger with small joys in the state of harmless happiness … in which they feel themselves to be master of the situation … lacking any element of surprise or adventure.   Let's go on this adventure of being loved and loving together.  I want you to come with me into the themes of this podcast.  I want you to really engage with what I'm presenting to you.  Not just listen like the Athenians listened to Paul about the resurrection of the dead.  Acts 17:32: Now when they heard of the resurrection of the dead, some mocked; but others said, “We will hear you again about this.”  But they weren't really that interested.  Only a few of the Athenians joined him.  Stay with me in this Episode 96 of Interior Integration for Catholics, released on August 1, 2022, and titled "I Am a Rock: How Trauma Hardens us Against Being Loved" I am Dr. Peter Malinoski, clinical psychologist, passionate Catholic and I am very pleased that we can share and engage with this information. Why do I think being loved is so important?   First because receiving love is absolutely essential.  It is our starting point in the spiritual life.  And second, because most people will not realxly allow themselves to be loved. Psychiatrist and Harvard Professor George Valliant wrote:  It's very hard, for most of us to tolerate being loved.-- That's been my experience as well.  The vast majority of people have chosen to severely limit how much love they will let in, how much love they will tolerate.   You can't love unless you are willing to be loved.   1 John 4:19:  We love because he first loved us  Look at the order here.  God loved us first.  We can't generate any love on our own.  We can reflect love, we can channel love, but we can't create love out of nothing like God can.  We have to cooperate in love and be open to love in order to love, in order to follow the two great commandments.   That is what this Interior Integration for Catholics podcast is all about -- it's about preparing the way for you to have a much deeper, richer and much more intimate relationship with God in the three Person of the Trinity -- Father, Son and Holy Spirit, and with the Blessed Virgin Mary our Mother.  A deep, personal relationship with God and Mary.  That's what  I want from you.  And if you won't tolerate taking in real love, if you deprive yourself of real love, you are going to wind up in a de facto hell on earth.  The most miserable people on earth are the loveless people -- loveless not because no one will love them -- but loveless because they actively or passively reject love.  And so many people do that.   And there are spiritual consequences to cutting ourselves off from real love.  Our heart become small, they become hard, they become closed, they become fearful, they fester in wounds.  And if we persist in refusing to be loved and to love, there is no other place for us to be in the afterlife than in hell.  That's what I think hell is -- a place for those who have refused love.  That's how serious all of this is.  Eternal consequences of the highest order.    Hallmark Movie Love What so many of our parts really want is what I call Hallmark movie love -- in Latin, this is rendered "Lovus Hallmarkius"  Hallmark love.  Yes, I've given it a ridiculous translation, but that because Hallmark love is not only a ridiculous concept, it's a dangerous one.  I mean it.  Really Dr. Peter -- all those sweet, feel-good Christmas movies?  What are you some kind of grinch, to criticize Hallmark movies?  I mean really, come on.. That's a bit much.  Hear me out, hear me out.   What is Hallmark love -- love is always just around the corner, painless, fun.  They are delightful.  Love is so gratifying and enjoyable, love takes away suffering. Clean and tidy.   It's a myth.  The Hallmark company is selling illusions.  Their movie production arm is peddling falsehoods about love to an audience who wants what they are offering to be true.  But it isn't.   Kristine Brown captured this theme in her online article Living in a Hallmark Movie  December 11, 2015  I want to live in a Hallmark movie.  I want to walk down the cobblestone Main Street into the corner coffee shop where everyone greets you with a smile and a Merry Christmas. I want to move to a new town where you immediately become acquainted with everyone and your child makes instant friends at school and there's always time to bake Christmas cookies and decorate trees and drink hot cocoa with peppermint sticks. I want to live in a Hallmark movie. I want to walk my child to school holding hands and have him tell me how much he loves me and what a great mom I am. I want to live where kids don't make bad choices and parents don't make mistakes. Where the toughest decision is whether to stay in the small town where you grew up or chase after a promising dream in the big city. Where things always just work out. And the movie always ends with a kiss from your true love and snow. Always snow. But life isn't a Hallmark movie, not even close. Example of the life of Christ -- the greatest lover ever, who died in making the greatest act of love ever, and it was nothing like a Hallmark movie.  We assume that we want love -- and we do.  Or parts of us do Made for love and in love -- That's a beautiful line in the Litanies of the Heart, written by Dr. Gerry for Souls and Hearts -- "Lord Jesus, you created me in love, for love."   Colossians 3:14  And above all these put on love, which binds everything together in perfect harmony.   Discussion of Parts Reference Episode 71: A New and Better Way of Understanding Myself and Others   Definition of Parts:  Separate, independently operating personalities within us, each with own unique prominent needs, roles in our lives, emotions, body sensations, guiding beliefs and assumptions, typical thoughts, intentions, desires, attitudes, impulses, interpersonal style, and world view.  Each part also has an image of God and a whole religion developed around its understanding of God, self, and the relationship between God and self.   Parts have different roles within the self system.  Narrow slice of experience, very limited vision.   Some parts don't care about being loved.  They are focused on never being hurt like that again.  They are focused on protection from harm, defending the self system against threats from others, very protective.  IIC 89:  Your Trauma, Your Body: Protection vs. Connection Conflict “I wished I didn't need an ocean of space to feel comfortable. I still wanted to be loved. Yet again I felt like two people: one who desperately needed a hug, and one who would break apart at the slightest touch. How could I get people to keep their distance without leaving completely? How long would it take for them to get tired of the way I flinched and evaded?” ― Ruby Walker, Advice I Ignored: Stories and Wisdom from a Formerly Depressed Teenager   Using a metaphor to describe how trauma hardens us against being loved  Overview Roots = unresolved trauma  Single trunk -- shame  Five Main stems -- acronym CRIES -- as in cries for help.    C R I E S -- Each of these main stems is driven by shame in the trunk, shame that results from the unresolved trauma in the roots.   Cognitions Relationships Identity Emotions Spirituality Each main stem has branches -- branches that cross and interweave in this big bush  And the branches have fruits.   Roots -- Unresolved trauma This includes the original trauma, original sin.   Underground, not seen --  Check out Episodes 88 and 89 -- a lot about the nature of trauma in those episodes  Primary effect of unresolved trauma is shame.   Single Trunk -- Shame Discussed shame at great length in Episodes 37 to 49 of this podcast.  Definitions of shame in episode 37:  Shame is:  a primary emotion, a bodily reaction, a signal,  a judgement, and an action.   I encourage you to go through those episodes again -- really get a grip on shame, because understanding shame is the key to understanding almost all psychological dysfunction, and understanding shame is the key to really comprehending why you have difficulties with your human formation.  Can't stress that enough.   Shame -- the central role of shame. Issue of survival.  Life and death.  Deep assumptions that my shame is so bad that it will kill me.  Our protector parts assume they have a need to defend against our exiled parts that have burdens of shame -- protectors believe they have to keep the shame out of awareness, keep it buried, distant.  They don't know that we can work with shame and the parts that carry the shame in collaborative, cooperative, constructive ways.  Our protector parts don't know that shame can be resolved -- the burden of shame can be lifted and there can be healing.   “When you're a child trapped in a situation of physical or psychological deprivation, you learn shame as an efficient, elegant mechanism of survival: shame simultaneously shields you from the reality that danger is out of your control (since the problem is not that you're unloved and deprived; it's that you're Bad) and prevents you from doing or saying anything challenging that might provoke a threat.” ― Kai Cheng Thom, I Hope We Choose Love: A Trans Girl's Notes from the End of the World Go back and really get the shame piece of this.   Main Stems off the trunk:  Cognitions, Relationships, Identity, Emotions, Spirituality -- Acronym CRIES  Emotions  Stem:  Five aspects Grief, Anger, Fear, Flooding, Shutdown  -- GAFFS -- so many of these emotions are generated by the shame that results from unresolved trauma Love is affective -- Bernard Brady -- discussed this at length in episode 94  Love is a movement from your heart, your soul -- a movement from the innermost depths of your being.  From your core self.  So the emotions are intimately involved with love   Grief  Emotional reaction to deep sense of loss.   Sadness about what you don't have that you need.   Parts want to be seen and heard and known and loved by the one who might love you.  All of you wanting to be loved.  All of you wanting to be healed.  So parts surge up, wanting to come to the surface.   Parts that carry grief have never been loved -- never been connected with in an emotional way, never been included in relationship with your innermost self or with others.  Never been seen. Anticipatory Grief -- if I allow myself to be love, I could lose that love.  The one who loves me could die.     Fear -- this is an emotion that drives so much fleeing from love.  This really is the big one.   Philophobia -- fear of love  All of us have parts that fear love.  Being loved arouses anxiety because it threatens long-standing psychological defenses formed early in life in relation to emotional pain and rejection, therefore leaving a person feeling more vulnerable.  Robert Firestone Fears of being revealed Fears of vulnerability Fears of loneliness Fear of the unknown Fears of being hurt one more time -- like Charlie Brown and Lucy and the football, winding up flat on your back again. Fears of betrayal  Fears of abandonment So much of this fear is driven by shame.   All this fear is a barrier to being loved.   “To fear love is to fear life, and those who fear life are already three parts dead.”  Betrand Russell All the bruised lives, searching hearts ... Everyone wants a love story but few will risk what it takes to live one. - Donna Lynn Hope Flooding:  Emotional overwhelm -- flooding.  Emotions become all dysregulated. Hyperarousal -- moving into fight or flight mode.  Intensity of emotions because very great. Often because old emotions from previous unresolved trauma are welling up -- parts that carry the burden of intense emotions want to be seen, heard, known and understood, they no longer want to be exiled, banished into the unconscious -- they want a voice, they want relationship they want redemptions.  Paul Simon  Don't talk of loveWell I've heard the word beforeIt's sleeping in my memoryI won't disturb the slumber of feelings that have diedIf I never loved I never would have criedI am a rock I am an island  “Our biggest challenge is that we have an overwhelming desire for an extraordinary love story but low capacity to hold space for it in our nervous system.”  ― Lebo Grand Dietrich von Hildebrand:  Fear of losing oneself in intense joys or griefs   Anger So much of this anger is driven by fear driven by shame  Our protector parts can use anger to distract from fear and grief.   Behind every angry soul is a wounded child that just wanted you to love them for who they are. Shannon L. Alder  Shutting down Avoiding inner experiences is one of Nathanson's four defensive scripts for avoiding shame.   Hypoarousal -- moving down out of the window of tolerance to the freeze mode.   Example of an electrical panel, or breaker panel v-- metal box with a door down in the basement or utility closet  with the main and the circuit breakers   Fruit: We have a very difficult time tolerating being loved when we are not in our window of tolerance.  Fight or flight mode or freeze mode -- we move very much into self-protection, to a focus on survival, on just perpetuating our existence.   We're not open to love -- we've moved into survival mode, not seeking connection.   We're not open to God.    Fr. Jacques Philippe, Searching for and Maintaining Peace:  The more our soul is peaceful and tranquil, the more God is reflected in it, the more His grace acts through us.  On the other hand, if our soul is agitated and troubled, the grace of God is able to act only with much greater difficulty… God is a God of peace.  He does not operate except in peace, not in trouble and agitation.  We need that emotional regulation, that sense of being in our window of tolerance to be able to connect with God.  So many times fear is identified as a barrier   Fear as a result of shame drove Adam and Eve into the bushes -- hiding from God John 14:27:  Peace I leave with you; my peace I give to you; not as the world gives do I give to you. Let not your hearts be troubled, neither let them be afraid. Cognition Stem  Perceptions extremely sensitive to stimuli  Very vigilant -- scanning for threats in the environment   Negative self-talk I am unloved  I am unlovable  I don't deserved to be loved -- bred in families where there is conditional love -- unattainable ideals of perfection  I will be seen and I will see myself.   I might contaminate anyone who would love me with my badness.   I won't live up to the love.   Doubts fostered about goodness in the world, about the nature of others Skepticism about who actually makes the effort to love  Demanding perfection from others before trying again.  To have the chance of being loved we have to take a chance on being destroyed inside -- Jo Nesbo Pessimistic evaluation of the future No one will love me  I will be deceived, tricked and then betrayed, rejected, abandoned   Distractions Paul Simon:   I have my booksAnd my poetry to protect meI am shielded in my armor  Fruit we can dwell inwardly, on our own damage -- we can focus on our wounds.  Direct our attention to all the things that are wrong with us and pull inward -- self-absorption, ruminating and obsessing about our defects, curling up inside to protect ourselves, not letting anyone in.  So common.   Or we can reach out and embrace love anyway.  We can trust that parts of us may be seeing things inaccurately, thinking about things in ways that are distorted.   Identity Stem  Drawing from Robert Firestone's  Why Do So Many People Respond Negatively to Being Loved? article on psychalive.org  I am inadequate, unworthy of love “We accept the love we think we deserve.”– Stephen Chbosky   Being valued or seen in a positive light is confusing because it conflicts with the negative self-concept that many people form within their family.  Firestone Being loved can provoke an identity crisis  Firestone Your identity, at least for some of your parts, can be very bound up in being unloved and unloveable   Parts may not know who you are if you were loved -- such a radical change Very disconcerting to lose a sense of who I am, even if the identity is a negative one.   Comfort in the familiarity of the dysfunction I know -- so I accept and even seek out rejection and failure -- they are familiar and harmonize with my life narrative.   Deep sense of having to earn conditional love.  But that is not what love is about “Love is not concerned with a person's accomplishments, it is a response to a person's being: This is why a typical word of love is to say: I love you, because you are as you are.” ― Dietrich von Hildebrand, The Art of Living   Little or no ordered self-love -- we will be discussing ordered self love in the next episode.  One of Nathanson's four strategies to cope with shame is to attack the self.   Internal disconnects to survive the trauma -- horror of abuse  Love relationships pull for integration Love is never fragmented; it's an inseparable whole which does not delight in bits and pieces. John A. Andrews  And that integration will bring up the parts of ourselves that we have rejected as too scary, too unacceptable, too unlovable, too dangerous, too overwhelming, too much in some way to be allowed a seat at the table of our consciousness.   Takes a lot of courage to really be loved.   Ursula Wirtz, Trauma and Beyond: The Mystery of Transformation “I consider love to be the matrix for this transformation, which calls new being into existence. Love has the power to reawaken and bring to the fire what has been entombed or distorted by traumatic forces or has retreated out of defensiveness and self-protection. Without love and compassion for the fragility of human identity in the face of death and the reality of evil, the madness found in these barren spaces of the soul might not be meaningfully encountered. For the stripping away of the constricting cocoon of traumatic fixations and the untangling of what has become distorted and convoluted during painful traumatization, love is needed.”  ―  Fruit -- will we let our burdened parts define ourselves-- will we let those traumatized parts of us, and the parts that guard us from those traumatize parts be the ones to determine who we are -- with their limited vision and their narrow slice of experience -- or can we work gently with ourselves and allow ourselves to be seen through the eyes of those who do love us.   Relationship Love affirms the other, love responds to the other, love is unitive -- love is steadfast more of Bernard Brady's characteristics of Agape, of real love described in episode 94   Effects of Shame Lack of trust in others   Lack of confidence How bold one gets when one is sure of being loved. Sigmund Freud  Fear of exposure To myself  To the one who loves me   “To be deeply loved, means a willingness to cut yourself wide open, exposing your vulnerabilities... hopes, hurts, fears and flaws. Hiding behind the highlight reel of who you are, is the real you and that person is just as worthy of love. There is nothing more terrifying or fulfilling, than complete love, it's worth the risk... reach for it.”  ― Jaeda DeWalt Fear of rejection The fear of rejection makes sense: If we've had a steady diet of shame, blame, and criticism, we learned that the world is not a safe place. Something within us mobilizes to protect our tender heart from further stings and insults .The Hidden Reasons We Don't Let Love In  -- John Amodeo Ph.D., MFT   The one who loves me will hurt me. It's inevitable   Fruit in the Behaviors -- all focused around protection from the other leading to relationship sabotage Undue criticism of the other --you are not enough for me.  Withdrawal and isolation -- one of Nathanson's strategies for coping with shame. Paul Simon Hiding in my room safe within my wombI touch no one and no one touches meI am a rock I am an islandAnd a rock feels no painAnd an island never cries  Avoidance  Pursuing unavailable people I found myself in a pattern of being attracted to people who were somehow unavailable, and what I realized was that I was protecting myself because I equate the idea of connection and love with trauma and death.” ― Zachary Quinto Pushing others away Basically, love is scary when it contrasts with childhood trauma. In that situation, the beloved feels compelled to act in ways that hurt the lover: behaving in a punitive manner, distancing themselves and pushing love away.  Robert Firestone  “You push people away, Marley. You don't realise it, but you do. You close yourself off to anyone and anything that doesn't fit in your perfect little hamster ball of life. But you can't experience love only on your own terms. It doesn't work that way.”  ― Kate Lattey, Dream On Aggression -- Fueled by anger. Attacking others is one of Nathanson's four strategies of coping with shame.  Why do we attack?  We are afraid, we are struggling with shame.     “Those who love to be feared fear to be loved, and they themselves are more afraid than anyone, for whereas other men fear only them, they fear everyone.     St. Francis de Sales   Emotionally disconnecting from the relationship Out of anger. Harden my Heart -- 1982 Hit Sung by Quarterflash  … I'm gonna harden my heart, I'm gonna swallow my tears, I'm gonna turn and leave you here  Out of fear and shame   “Many freeze types unconsciously believe that people and danger are synonymous, and that safety lies in solitude. Outside of fantasy, many give up entirely on the possibility of love. The freeze response, also known as the camouflage response, often triggers the individual into hiding, isolating and eschewing human contact as much as possible. This type can be so frozen in retreat mode that it seems as if their starter button is stuck in the ‘off' position. It is usually the most profoundly abandoned child - ‘the lost child' - who is forced to ‘choose' and habituate to the freeze response… Unable to successfully employ fight, flight or fawn responses, the freeze type's defenses develop around classical dissociation.” ― Pete Walker Dietrich von Hildebrand -- shrinking away from commitment.   Difficulties receiving partial, incomplete, imperfect love -- as replacements for God's love Glazed carrots.  Side dish, not the main entrée.   Mother Angelica's Little Book of Life Lessons And Everyday Spirituality :  Allow people to love you as they must love you, not as you want them to love you. Even God does not love us as we wish Him to. Learning to love is learning to accept love as it comes   Spiritual Disconnecting from God, who is love.   Human beings must be known to be loved; but Divine beings must be loved to be known.  Blaise Pascal We to love God to know Him  And so we have to find him lovable -- and so often parts of us don't find him lovable.   Need for Faith and Hope -- Infused virtues.   To be loved but not known is comforting but superficial. To be known and not loved is our greatest fear. But to be fully known and truly loved is, well, a lot like being loved by God. It is what we need more than anything. It liberates us from pretense, humbles us out of our self-righteousness, and fortifies us for any difficulty life can throw at us. Timothy Keller everyone wants perfect love... no one wants to be a perfect lover... - Author: Brijesh Singh   Being loved by God is often even more difficult I John 4:8  "…God is love."  Issues around God images (IIC 23-29)  God is not as tangible, immediate  Transferences to God  Projections onto God.   Edward Vacek:  Love, Human and Divine: The Heart of Christian Ethics.  The sequence in loving and being loved.    (1) God affirms us; (2) God receives a; (3) we accept God's love; (4) we affirm God; (5) God forms community with us; (6) we cooperate with God in loving God in the world; and finally (7) we grow in a limited code responsibility with God. p.. 177 Problems with the sequence -- not tolerating enough contact with God  to be affirmed, to understand him in a totally different way.   1 John 4:19:  We love because he first loved us   Active vs. passive refusal to be loved.   Active refusals to be loved are more obvious Passive refusals to be loved are more common.   Five attachment tasks Felt sense of safety and protection -- have to go through the valley of shame, fear, anger, grief  Feeling seen, heard, known and understood -- have to tolerating being in relationship, being present.   Feeling comforted, soothed and reassured  Feeling cherished, treasured, delighted in   “If your parents' faces never lit up when they looked at you, it's hard to know what it feels like to be loved and cherished. If you come from an incomprehensible world filled with secrecy and fear, it's almost impossible to find the words to express what you have endured. If you grew up unwanted and ignored, it is a major challenge to develop a visceral sense of agency and self-worth.” ― Bessel A. van der Kolk, The Body Keeps the Score: Brain, Mind, and Body in the Healing of Trauma Feeling the other has your best interests at heart Love heals The more healthy relationships a child has, the more likely he will be to recover from trauma and thrive. Relationships are the agents of change and the most powerful therapy is human love. — Bruce D. Perry  “Love alone brings a human being to full awareness of personal existence. For it is in love alone that man finds room enough to be what he is.” ― Dietrich von Hildebrand, Man, Woman, and the Meaning of Love   “Trauma ruptures and hollows. Compassion mends and fills; love heals.” ― Na'ama Yehud There you have it from a trauma researcher, a philosopher, and a writer --  Example of Sr. Josephine Bakhita Born about 1869 in the village of Olgossa in the Darfur region of Sudan. She was a member of the Daju people  Uncle was a tribal chief, well-to-do family  At age 8, kidnapped by slave traders, forcerd to walk barefoot 600 miles to a slave market  Over the next 12 years, bought and sold many times, at least 12 times  Trauma of the abduction -- Forgot her given name in captivity -- consider that - - a loss of identity   Owners varied in their treatment of her.  Some were sadists  Family of  Turkish general Josephine wrote that as soon as one wound would heal, they would inflict another.  another woman drew patterns on her skin with flour, then cut into her flesh with a blade. She rubbed the wounds with salt to make the scars permanent. She would suffer a total of 114 scars from this abuse. A total of 114 intricate patterns were cut into her breasts, belly and into her right arm   I am definitively loved and whatever happens to me --  I am awaited by this Love.  Action Plan You gotta pray   Point is to focus on developing the relationship with the Persons of the Trinity and with Mary -- as a little child, a little son or daughter.   Litanies of the Heart - the Litany of the Closed Heart the litany of the fearful heart, the litany of the wounded heart.  Soulsandhearts.com/lit Books Intimacy in Prayer -- Personal Prayer:  A Guide for Receiving the Father's Love -- by Frs. Thomas Acklin and Boniface Hicks.  Fr. Jacques Philippe -- Time for God -- excellent guide for learning pray from a more relational perspective.  I also like Fr. Jacques Philippe's book The way of Trust and Confidence  Fr. Thomas Dubay -- Fire Within -- more of a Carmelite approach.  If you haven't been to confession recently, go.  If you feel like you can't go, I want to hear about it.   Calling all Catholic therapists and -- Interior Therapist Community is starting our fall groups.   80 therapists and graduate students in mental health fields in community -- each of us working on our own human formation, but not in isolation.  New Foundations experiential groups are forming -- and we have advanced groups.   2022 Webinar Series: Of Beams and Specks: Therapist-Focused Consultation - Peter Malinoski  $30 Soulsandhearts.com/itc -- call me at 317.567.9594 or email at crisis@soulsandhearts.com  Weekly reflection -- related to this podcast, delivered to your inbox every Wednesday --  We do get around to archiving them in the blog section of our website -- soulsandhearts.com/blog Conversation hours -- every Tuesday and Thursday from 4:30 PM to 5:30 PM Eastern Time call me at 317.567.9594 or email at crisis@soulsandhearts.com.  If I don't pick up, I'm on another call leave a voicemail.   Patroness and Patron.

Summary:  In this episode, we focus on how unresolved trauma undermines and sabotages both our capacity and our inclination to love well.  We explore how unresolved trauma impacts each of the five characteristics of love -- compromising our ability to love in an affective (emotional), affirming, responsive, unitive and steadfast way.  We also dive into how so trauma pulls us to focus inward, and to protect ourselves, undercutting the vulnerability and willingness to engage that are required for deep love and we discuss hope for change.   Lead-in  They say love is blind, but it's trauma that's blind. Love sees what is.“ — Neil Strauss, The Truth: An Uncomfortable Book About Relationships And Neil Strauss is right on that.  Love connects with reality.  With God who is the ultimate realness, the ultimate being, the I AM.   Trauma is blind and it blinds us.  That's what we are talking about today.  Trauma and its impact on live.   Intro: Dear listener, You and I are together in the adventure of this podcast, Interior Integration for Catholics, we are journeying together, and I am thankful to be with you.   I am Dr. Peter Malinoski, clinical psychologist and passionate Catholic and together, Why are we here?  We are here together to bring you the best of psychology and human formation and harmonize it with the perennial truths of the Catholic Faith. So we can have the best of both.  That's why.   Today, we're going to take a broad perspective, a bird's-eye view of trauma's destructive consequences to our capacity to love.  What is the effect of trauma on our capacity and inclination to love?  That is the question for us to explore together today.   So welcome to episode 95,  of Interior Integration for Catholics, titled Trauma's Devastating Impact on our Capacity to Love, released on July 4, 2022, Independency Day in the USA, This podcast, Interior Integration for Catholics is part of our broader outreach, Souls and Hearts bringing the best of psychology grounded in a Catholic worldview to you and the rest of the world through our website soulsandhearts.com.   Review Trauma.  We are in the midst of  whole series of episodes on trauma.  So just a brief thumbnail review.   Started with Episode 88 Trauma: Defining and Understanding the Experience  Really important to understand the inner experience of trauma -- so you can recognize it in your own life and recognize it an empathetic and attuned way in others' loves.  Part of loving them.   Episode 89 Your Trauma, Your Body: Protection vs. Connection --  a current understanding of how large a role our bodies have in our experience of trauma.  Our bodies.   Episode 90:  Your Well-Being: The Secular Experts Speak  we review how philosophers and modern secular psychologists understand mental health and well-being.  In this episode, we look at the attempts to define what make us happy, from the 4th century BC to the present day.  Aristippus, Aristotle, Descartes, Freud, Seligman, Porges, Schwartz, and two diagnostic systems.  We take a special look at how positive psychology and Internal Family Systems see well-being.   Episode 92:  Understanding and Healing your Mind through IPNB  neuropsychiatrist Dr. Dan Siegel's Interpersonal Neurobiology (IPNB) and what IPNB can show us about psychological health.  We review the triangle of well-being, the nature of secure attachments, and the basis for mental health from an IPNB perspective.  We examine the characteristics of a healthy mind and how it functions, and the two signs that reliable indicate all psychological symptoms and mental dysfunction.  We discuss the nine domains of integration Three inner experiential exercises in Episode 93 Episode 94:  The Primacy of Love  In this episode, I discuss the central importance of love as the marker of well-being from a Catholic perspective -- our capacity to live out  the two great commandments.  We explore how love is the distinguishing characteristics of Christians, and we discussed Catholic theologian Bernard Brady's five attributes or characteristics of love -- how love is affective, affirming, responsive, unitive and steadfast.  We discuss what is commonly missing from philosophical and theological approaches to love, and we briefly touch in the death of love and distortions of love.  So check those out if you haven't already.  This    Going to address love in general -- focusing on loving  In future episodes, will review  Tolerating being loved Brady quxote   Ordered self-love   The experience of trauma screws up our loves -- where we go to find good.  It screws up where we are seeking, how we seek to be loved and how we seek to love.   St. Augustine:   He lives in justice and sanctity who is an unprejudiced assessor of the intrinsic value of things.  He is a man who has an ordinate love: he neither loves what should not be loved nor fails to love what should be loved. On Christina Doctrine, I, 27 We need ordered love.  Why -- Bernard Brady put it -- Because we become like what we love.  Whatever we embrace in our love, we become like that person or that thing.   As Augustine considered the dissipation of this youth, he wrote "I loved beautiful things of a lower order, and I was going down to the depths."   Confessions.   So much of the problem with disordered love  comes from misdirected seeking to get your attachment needs meet.  That's the problem. We have legitimate attachment needs  Trauma strips away our sense of  A felt sense of Safety and security Feeling seen, heard, known and understood Feeling comforted, soothed, reassured Feeling cherished, treasured, delighted in Feel the other person wills my highest good.   All from Brown and Elliott 2016, Attachment disturbances in Adults Where do we find our safety and security?  In both the natural and spiritual realms, we find it in attachment security needs being met.  Five primary attachment security needs (Brown and Elliott)  A felt sense of safety and protection, a deep sense of security, felt in my bones It makes it so much easier to love when we feel safe and secure.    "People want to be safe, and comfortable. If safety and comfort is to be found in guns, then they will take up guns—of their own accord, in their own need. And when safety and comfort are found in libraries, then the guns rust.“ — Algis Budrys American writer  Source: Some Will Not Die (1961), Chapter 6 (p. 122)   Feeling seen, heard, known, and understood   I want, by understanding myself, to understand others.“ — Katherine Mansfield New Zealand author 1888 - 1923 Being comforted, soothed, and reassured Feeling valued, cherished, treasured, delighted in You are my sunshine published by Jimmie Davis and Charles Mitchell on January 30, 1940   You are my sunshineMy only sunshineYou make me happyWhen skies are grayYou'll never know, dearHow much I love youPlease don't take my sunshine away Feeling that the other person wills my highest good, the best for me We have to turn inward to find the road to God.   Etienne Gilson explained Augustine's approach to God as "a path leading from the exterior to the interior and from the interior to the superior."  Gilson, The Christian Philosophy of St. Augustine p. 20 Charles Taylor:  Sources of the Self: By going inward, I am drawn upward.  The Making of Modern Identity 134 Turning inward is the route to God, not God.  Brady, 120 Often resisted by Catholics as being selfish.   Edward Vacek:  Love, Human and Divine: The Heart of Christian Ethics.  The steps in loving and being loved.    (1) God affirms us; (2) God receives a; (3) we accept God's love; (4) we affirm God; (5) God forms community with us; (6) we cooperate with God in loving God in the world; and finally (7) we grow in a limited code responsibility with God. p.. 177 1 John 4:19 We love, because he first loved us.     Last episode -- Bernard Brady's description of the five characteristics of Love  Christian Love: How Christians through the Ages have Understood Love.-- drawing heavily from the work of phenomenologists  Jules Toner and Margaret Farley Love is affective, affirming, responsive, unitive and steadfast.  (repeat)  Five characteristics.  Five aspects.  Repeat.   We described and discussed these at length in the last episode, episode 94 of the IIC podcast, The Primacy of Love  We will briefly review each of them And then discuss how trauma impacts each of them, bringing in the effects or the sequelae of trauma from Episode 88 --  Trauma: Defining and Understanding the Experience.   Love is affective  Love is an emotion Love is a movement from your heart, your soul -- a movement from the innermost depths of your being.  From your core self.  St. Thomas Aquinas in the Summa:  Consequently the freezing or hardening of the heart is a disposition incompatible with love: while melting denotes a softening of the heart, whereby the heart shows itself to be ready for the entrance of the beloved.“ Love rejoices in the beloved  Love rejoices in the beloved -- Protestant Theologian R.H. Neibuhr writes in his 1977 book the Purpose of the Church and Its Ministry:  By love, we mean at least these attitudes and actions: rejoicing in the presence of the beloved, gratitude, reverence, and loyalty toward him.  p.35 „After a traumatic experience, the human system of self-preservation seems to go onto permanent alert, as if the danger might return at any moment.“  Judith Herman Brené Brown US writer and professor 1965 Source: The Gifts of Imperfection: Let Go of Who You Think You're Supposed to Be and Embrace Who You Are  Staying vulnerable is a risk we have to take if we want to experience connection.  Misattributed to Sigmund Freud Out of your vulnerabilities will come your strength. Brady:  Love is the directive and dominant center of emotions.  p. 267  Many emotions are associated with love Delight, Bliss, Happiness  A sense of fulfillment  Warmth  Grief  Sadness  Anxiety  Distress   If there is no emotion, there is no agape, no love.  The heart must be moved for love to be anything like complete.  We cannot love like a Vulcan, like Mr. Spock without emotion.  „Even the most elevated psychological understanding is not a loving understanding.“ — Karl Jaspers German psychiatrist and philosopher 1883 - 1969 Effects of trauma -- from episode 88, Trauma: Defining and Understanding the experience  Emotional and Psychological effects Emotional overwhelm  Shock  Shame as an emotion  Guilt  Irritability, anger, rage   Anxiety, fear, panic attacks, phobia, panic attacks, Fears of trauma repeating Jenny Han, book Always and Forever, Lara Jean  Being vulnerable, letting people in, getting hurt… it's all part of being in love.   Sadness, depression  Mood swings   Hopelessness, despair Emotional constriction, shutting down Difficulty experiencing positive emotions Anhedonia Apathy Brady 273.  Love does not die because of hate but because of apathy.   Cognitive Effects -- impact on sensation, perceptive, higher-order thinking Alexithymia -- inability to recognize or describe one's own emotions -- can't put my feelings into words.   Can't conceptualize your feelings either Feelings in others could be overwhelming -- can't recognize what others are feeling Can't express my feelings well Can't connect affectively, emotionally. That takes vulnerability   Confusion, distraction  Spacing out with dissociation   Physical Effects of trauma -- preoccupation with the body   Behavioral Symptoms Relational apathy  Social withdrawal   Existential Symptoms Despair about humanity -- overgeneralized to the other person  Cynicism  Disillusionment   Identity issues -- shame.   I'm not worth you connecting emotionally with me What could I ever offer you emotionally? I'm such a downer. Strong self-criticism  Fragmentation Love is affirming Love affirms the other  Love says yes to the other person at the same time as love says yes to oneself.   "Agape is the simple yet profound recognition of the worthiness of and goodness in persons."  p. 268  Edward Vacek:  Love is an affective, affirming participation in the goodness of a being (or Being).… Love is an emotional, affirming participation the dynamic tendency of an object to realize its fullness.”  Brene Brown -- Rising Strong  Vulnerability is not winning or losing; it's having the courage to show up and be seen when we have no control over the outcome. Vulnerability is not weakness; it's our greatest measure of courage.“   Affirmation happens at two levels One level is the basic level of human dignity shared by all persons.   Second level of affirmation is the uniqueness of the person.   When you love your neighbor you truly see the other as a person.   Jules Toner, SJ -- "I love you because you are you." We need to affirm at both levels.  The basic dignity of the person and the uniqueness of the person.   Affirmation implies acceptance of the other and knowledge of the other.    This is not an endorsement of the other's vices or bad habits, but a recognition of them and an acceptance of who the person is as an entire being.  Not picking and choosing the attractive bits.  Self-acceptance of the same things. Affirmation requires freedom -- freedom to get outside the self.   Effects of trauma  Emotional and Psychological effects  Turning inward -- self-protection. Connections vs. protection -- Episode 89 Where is the safety?   How can I escape the danger?  Not letting anyone in to love me.   Feeling disconnected or numb or detached -- dorsal vagal response.  Freeze response.  Deer in the headlights Bodily response Emotional Constriction, Shutdown   Shame -- what is my affirmation of you worth?  I'm not worth much, my affirmation isn't worth much.  Feeling very fragile, vulnerable -- not resilient enough --  I can't engage  Irritability, hostility,  Depression -- lethargy  Mood swings -- unpredictability, others can't trust me.   Emotional detachment, disconnection -- in relationships  Helplessness  Difficulty experiencing positive emotions  How can I reach out?  White knuckling. Feels very forced.  Cognitive Effects -- impact on sensation, perceptive, higher-order thinking Racing thoughts -- so distracting, I can attend to you, I can't attune to you, I can't affirm you.  My house is on fire.   Extreme alertness - suspicion of you -- are you a threat?  Will you trigger me?   Physical Effects   Behavioral Symptoms Argumentative behavior  Social withdrawal and relational apathy.  Avoidance   Existential Symptoms Ruminating about evil in the world   Identity issues -- shame If I affirm you I will see myself in a bad light because of my shame  Affirmation involved a positive evaluation -- so tempting to see myself negatively.   Fragmentation  Lack of affirmation from the whole self Toner [Radical love] "is giving self; for it is myself who am in the loved one by my love, not merely by my possessions, or even my thoughts, my wit, my joy, my wisdom, my strength.  It is I myself."   Toner:  Loving someone in depth… Means loving from the lovers most personal self, with sincerity, intensity, endurance… To affectively affirm this unique person in a response informed by full, detailed knowledge, which catches the delicate shadings of his profoundest attitudes, moods, likes, and dislikes, ideals, fears, hopes, capabilities, weaknesses, etc.  The experience of love 160   Love is Responsive  Love is an active response for the well-being of the other.  This is where Brady includes benevolence.  It's about participating in the promotion of the highest good for the other, potential for the other's full humanity. How can I help you to flourish?  How can I help you toward your highest good?   This is where self-sacrifice comes in.   love will call for self-sacrifice.   Responsiveness implies an attunement to the other -- a resonance, and understanding.  The capacity to respond well.  It's not just any responsiveness.  The ability to be aware of and to respond effectively to the needs of my neighbor.  So there is a capacity about this.  It's not just an act of the will.  Attunement can be described as a kind of resonance.  Toner:  Radical love is experience as being in accord with the loved one, vibrating as it were, in harmony with the beloved's act of being and so with the whole melody of the beloved's life.  It is a welcoming of the loved one into the lover's self and his life-world, as fitting there, making a harmony with the lover's being and life.   But there must also be action:  "Let us love, not in word or speech, but in truth and action."  ` John 3:18. Parents "Doing the best they can"  Love bottled up inside.  -- Not expressed.  Then it's not love.  Love that is not shared, that is not relational is not love.   Brene Brown:  Of all the things trauma takes away from us, the worst is our willingness, or even our ability, to be vulnerable. There's a reclaiming that has to happen.  Rising Strong 2015 Madeleine L'Engle Walking on water (1980) When we were children, we used to think that when we were grown-up we would no longer be vulnerable. But to grow up is to accept vulnerability… To be alive is to be vulnerable.  To love at all is to be vulnerable. Love anything, and your heart will certainly be wrung and possibly be broken.“ — Clive Staples Lewis, book The Four Loves   The Letter of James 2:45-17.   What does it profit, my brethren, if a man says he has faith but has not works? Can his faith save him? If a brother or sister is ill-clad and in lack of daily food, 16 and one of you says to them, “Go in peace, be warmed and filled,” without giving them the things needed for the body, what does it profit?  So faith by itself, if it has no works, is dead. Responsive to needs  Not just physical needs, but the emotional needs, psychological needs, relational needs   St. Bernard of Clairvaux:  We must remember that love reveals itself, not by words or phrases, but by actions and experience.  It is Love with speaks here, and if anyone wished to understand it, let him first love.   Effects of trauma  Emotional and Psychological effects Overwhelm  Shock  Shame  Irritability, anger, rage  Anxiety, fear, apprehension  Guilt  Sadness, depression, grief  Helplessness, despair  Mood swings -- swept away by our own experience  Anhedonia -- difficulty experiencing positive emotions.  Apathy   Protection vs. connection.  I'm on fire inside, I am frozen inside.  It's chaotic inside Intense self-preoccupation.  Not selfishness.  It's really hard to judge the moral quality of these things accurately.   When we are preoccupied with the intensity of our own experience, it's hard to be responsive to the other person.     Cognitive Effects -- impact on sensation, perceptive, higher-order thinking “When something reminds traumatized people of the past, their right brain reacts as if the traumatic event were happening in the present. But because their left brain is not working very well, they may not be aware that they are re-experiencing and reenacting the past - they are just furious, terrified, enraged, ashamed, or frozen.”  ― Bessel Van Der Kolk Difficulty concentrating, even focusing on the other person.  Confusion.  Others sense the disconnect.  Not attuned.    Guardedness -- protecting against vulnerability Questioning "Why me?" makes it hard to respond to you.     Physical Effects Behavioral Symptoms Startle responses   Argumentative behavior Social withdrawal and relational apathy.  Avoidance Reducing activity levels Existential Symptoms I am permanently damaged.  How could I ever be responsive in love.  Who would want me?  Can be unconscious.   Identity issues -- shame I am permanently damaged.   Fragmentation -- not a consistent, complete, unified response to the other -- partial responses that seem very incomplete, maybe insincere to the other person.  Love requires our whole being Fr. Jules Toner:  in the full concrete experience of love, our whole being, spirit and flesh, is involved: cognitive acts, feelings and affections, freedom, bodily reactions – all these are influencing each other and all are continually fluctuating in such a way as to change the structure and intensity of the experience. The experience of love. P. 65 Love is Unitive Brady:  The fruit of love is unity.  Love unites.  It is in the very nature of love to bring together.  p. 279  Brady:  When you love, you step out of yourself and experience the other.   There is still a separateness.  Not a blending or a fusion or a loss of identity.  But you are no longer just within yourself.  You've entered into the space of another.   And you've allow the other to enter into your space Loving an enemy -- you are like me.  We are similar on a fundamental human level -- No dehumanization.  Agape pulls for unity, even with strangers.   The mystics describe the unity we are called to in God -- Union with God.   Jules Toner: Radical love is not a tendency affection but a being affection by which I am in union with, am present with the loved one.   Effects of trauma -- Protection vs. Connection  Emotional and Psychological effects Emotional instability, inconsistency -- unpredictability.  Makes it hard for the other to trust you.   Preoccupation pulls you inside -- guilt, shame -- self protection. St. Augustine:  "..if [a man] loves himself on his own account, he does not turn himself toward God, but being turned toward himself, he does not care for anything immutable…."  On Christian Doctrine, Book 1, Chapter 22  And the why doesn't matter nearly so much as people think it does.   Evil comes from loving some good thing inordinately -- blog post on this -- check it out.  Dangerous love, from June 22, 2022 That good thing might be the means that parts of us are seeking to try to provide us with a sense of safety and security.   Fear of vulnerability When trust is lost, traumatized people feel that they belong more to the dead than to the living.“ — Judith Herman Trauma and Recovery  Love is a battlefield  -Pat Benatar 1983 -- music video about all the conflict with her father, and with others seeking to use her as a sexual object.   Fear of overwhelming suffering  Shutdown  Alexithymia   Cognitive Effects -- impact on sensation, perceptive, higher-order thinking Distraction, rumination, racing thoughts interfere with capacity to attune, to unite  So much internal stimulation -- so much internal noise -- makes it difficult to resonate with the other person, to really understand the other -- to enter into the other's phenomenological world.   So much of that distraction is around finding safety and protection -- cognitive restlessness  Dissociation and disconnections are experienced as off-putting.  Have you ever been with someone who is spacing out when you are talking with them?   Physical Effects   Behavioral Symptoms Blaming  Discharging anger and aggression -- parts so want to be heard and healed.   Desperation can lead to boundary crossings and boundary violations.   Attempts to use the other person to meet intense needs -- not a conscious effort to exploit the other, but exploitation can happen anyway.   Existential Symptoms Shame -- feeling unworthy of connection  Not knowing who I am -- makes it really complicated to be in relationship.   Identity issues Fragmentation - which part of me is uniting with you right now? What are other parts doing.   The need for disconnects within in order to not be overwhelmed - inevitably leads to disconnects with other people You can't give what you don't have.   I'm not lovable, why would you want to be united with me?   Dissociation Identity alteration: The sense of being markedly different from another part of yourself  Identity confusion: A sense of confusion about who you really are   we will have a lot more to say about dissociation in future episodes, but for now -- disconnection. I need to know who I am and I need to know who you are to know who we are together, in relationship.  Love is steadfast God's love endures.  Psalm 891-2  I will sing of thy steadfast love, O Lord,[a] for ever;     with my mouth I will proclaim thy faithfulness to all generations.For thy steadfast love was established for ever,  It may not always be mutual or reciprocal People want predictability Steadfastness requires resilience, to roll with the punches in the relationship.  Any close relationship will have conflicts and difficulties. The fragility in the system that trauma imposes is a real obstacle to resilience necessary to be steadfast in relationship, to not quit and walk away from loving the other person.   Jules Toner:  "The lover is present to the loved one and has the loved one present to himself."   The experience of love, 117 Effects of trauma  Emotional and Psychological effects Mood swings -- effect of different parts, each with its own intense emotions  Helplessness -- despair -- can be intermittent  Emotional shutdown -- dorsal vagal response.   Being reactivated or triggered emotionally.   Disappointment in the other -- you are not helping me Can lead to frustration and rejection.   Cognitive Effects -- impact on sensation, perceptive, higher-order thinking Intrusive thoughts, intrusive memories.   Dissociation is a mental process of disconnecting from one's thoughts, feelings, body, from memories or sense of identity. This disconnection is automatic and completely out of the person's control. Amnesia: Often described as "gaps" in memory that can range from minutes to years  Depersonalization: Feeling disconnected from your body or thoughts  Derealization: Feeling disconnected from the world around you   Physical Effects Impact of hyperarousal  Impact of hypoarousal   Behavioral Symptoms Withdrawal  Avoidance -- refusal of consistent vulnerability  Alcohol and drug use   „For me, vulnerability led to anxiety, which led to shame, which led to disconnection, which led to Bud Light.“ — Brené Brown US writer and professor 1965 Source: Daring Greatly: How the Courage to Be Vulnerable Transforms the Way We Live, Love, Parent, and Lead  Switching among parts Existential Symptoms Deep sense of not being loved, not being lovable  There is no love in the world.  At least not for me.  So why unite with anyone.  Loss of meaning and purpose.  Identity issues Fragmentation  Unstable identity makes it hard to be consistent in the loving   The death of love Brady 273.  Love does not die because of hate but because of apathy.  The death of love is often preceded by the denial of the basic dignity of the other.  The death of love happens when we reject instead of affirm the other's special personal and unique goodness.  The death of love is encouraged when we ignore the other's needs and wants while prioritizing our own wants.  The deal of love occurs when we pursue discord, division, disassociation, and distance in the place of unity.   That is sin.   Malice is not necessary for love to die.  Apathy doesn't have malice in it. In apathy, the other does not register in your consciousness.  He or she doesn't matter. He or she doesn't exist for you.   We don't have to active deny the basic dignity of the other.  We just have to not notice it.  Not attend to it We don't have to actively reject the other's special and unique goodness, we just have to not notice it, not attend to it.   We don't have to actively ignore the other's needs and wants -- we just have to be preoccupied with our own trauma and its effects.     Hope Romans 8:28 We know that in everything God works for good[a] with those who love him,[b] who are called according to his purpose.  Julian of Norwich:  And because of the tender love which our good Lord has for all who will be saved, he comforts readily and sweetly, meaning this: it is true that sin is the cause of all this pain, but all will be well, and every kind of thing will be well.   Widow's mite Luke 21:1-4  He looked up and saw rich people putting their gifts into the treasury; 2 he also saw a poor widow put in two small copper coins. 3 He said, “Truly I tell you, this poor widow has put in more than all of them; 4 for all of them have contributed out of their abundance, but she out of her poverty has put in all she had to live on.”  Ratios   Martin Luther King:  Love even for enemies is the key to the solution of the problems of the world.  Strength to Love 47-48  Psychologist Peter Levine:  Trauma is hell on earth. Trauma resolved is a gift from the gods.  Romans 5:20 ..where sin increased, grace abounded all the more,  1 John 3:1  See what love the Father has given us, that we should be called children of God; and so we are. The reason why the world does not know us is that it did not know him.  Romans 8 35-39  Who will separate us from the love of Christ? Will hardship, or distress, or persecution, or famine, or nakedness, or peril, or sword?  As it is written, “For your sake we are being killed all day long; we are accounted as sheep to be slaughtered.” No, in all these things we are more than conquerors through him who loved us. 38 For I am convinced that neither death, nor life, nor angels, nor rulers, nor things present, nor things to come, nor powers, 39 nor height, nor depth, nor anything else in all creation, will be able to separate us from the love of God in Christ Jesus our Lord.   Call to Action Kent Keith The Paradoxical Commandments -- Resilience.  Mother Theresa had pinned this up in one of her convents.    People are illogical, unreasonable, and self-centered.   Love them anyway.If you do good, people will accuse you of selfish ulterior motives.   Do good anyway.Honesty and frankness make you vulnerable.   Be honest and frank anyway.What you spend years building may be destroyed overnight.   Build anyway.People really need help but may attack you if you do help them.   Help people anyway.Give the world the best you have and you'll get kicked in the teeth.   Give the world the best you have anyway.   Where we are going If you want to love, you have to first be loved and know you are loved.   Tolerating being loved -- many people assume that we just want to be loved -- that's not anything like entirely accurate.  1 John 4:19 We love, because he first loved us. Ordered self love.    Check out our blogs -- weekly email reflections  June 15 -- Seven ways to understand sin     Sin as breaking the law    Sin as a burden    Sin as a debt    Sin as “missing the mark”    Sin as a violating your conscience    Sin as breaking or harming relationships    Sin as the failure to love, or the “anti-love” June 22  Dangerous Love -- we really get into St. Augustine's description of sin as a disordered or misdirected love, and I share how when we that misdirected love is oriented toward getting our attachment needs met, it's not only misdirected love, it's a dangerous love.   June 29 Conflicting loves inside you -- we get into how to understand the conflicting loves inside of us -- from a parts perspective -- multiplicity and unity of the self.   Email me crisis@soulsandhearts.com  -- call my cell 317.567.9594 any Tuesday or Thursday from 4:30 PM to 5:30 PM Eastern time for conversation hours.   Let others know about this podcast.  Put the word out.  There's somebody you know dealing with trauma -- get them on board with the rest of us with the IIC podcast.  All the major podcast player -- Apple Podcasts, Spotify, Google Podcasts, Stitcher, Audible, Podbean, Podchaser, CastBox, Overcast, Podcast Addict, all of them, we're on all of them.  Soulsandhearts.com/iic You have until July 10.  The RCC -- Come with me on an adventure.  Come with me on an adventure of being loved and of loving.  That is what the Resilient Catholic Community is all about.  Check out the Resilient Catholics Community at soulsandhearts.com/RCC  The RCC is all about working through your human formation issues -- the ones that inhibit you from receiving the love you need and from loving God completely, with every fiber of your being, with your body,  with all your parts, with all your emotions, thoughts, all your inner experience with all of you, with no part of you left behind, no part of you left out.   It's all about learning to be gentle but firm with yourself -- it's all about integration.  It's all about resilience.   All about restoration -- recovering from being dominated by shame, fear, anger, sadness, pessimism, whatever your struggle is in the depths of your human formation And we do this work experientially -- so many experiential exercises -- this is not just intellectual knowledge, we're working with all of you. Informed by Internal Family Systems and the best of the rest of psychological and human formation resources  All grounded in a Catholic understanding of the human person  All focused on helping you to better accept love and to love more fully, to carry out the two great commandments of our Lord.   Are you up for the challenge?  Would you like to join me and the rest of the pioneers in this adventure?  Do you want to be a part of the community?   Are you ready to prevail over whatever hinders your human formation -- would you like to no longer be dominated by fear, anger, shame, sadness, pessimism?  And would you like to be with other like-minded Catholics on the journey -- If so join me.  Join all of us in the Resilient Catholics Community.  The RCC We are taking applications throughout until July 10 -- extended the deadline.   for our third cohort, those in that cohort will start their adventure in June and July by taking our Initial Measures Kits and be getting feedback on their parts in a personal Zoom session with me.  It's a great chance for us to get to know each other, really know each other at the level of parts.  You'll get a 5 or 6 page report on your internal system and then be eligible for our weekly company meetings and programming to begin in late August or early September.   Talk with me about it in conversation hours call my cell 317.567.9594 any Tuesday or Thursday from 4:30 PM to 5:30 PM Eastern time for conversation hours.   Patroness and Patron   

Dr. Diwakar Davar and Dr. Jason Luke, both of the University of Pittsburgh's Hillman Cancer Center, highlight key advances in early phase therapeutics and immunotherapy that were featured at the 2022 ASCO Annual Meeting and also address toxicities, including immune checkpoint inhibitor-associated myocarditis. TRANSCRIPT Dr. Diwakar Davar: Hello, and welcome to the ASCO Daily News Podcast. My name is Dr. Diwakar Davar, and I'm an assistant professor of Medical Oncology, specializing in melanoma and phase 1 therapeutics at the University of Pittsburgh's Hillman Cancer Center. I am the guest host of today's podcast. My guest today is Dr. Jason Luke, a colleague and the director of the Cancer Immunotherapeutics Center at the UPMC Hillman Cancer Center here.  Today, we'll be discussing advances in early-phase therapeutics and immunotherapy that were featured at the 2022 ASCO Annual Meeting.   You'll find our full disclosures in the show notes, and the disclosures of all guests on the podcast are available on our transcripts at asco.org/podcasts.  Jason, thank you for coming on the podcast today.  Dr. Jason Luke: Thanks so much for the invitation. It was a great ASCO, and I hope everyone had a good time.  Dr. Diwakar Davar: So, onto our abstracts. So, the first one that we'll be discussing, and Jason as you know we've done this before. We'll be rapidly transitioning between phase 1 therapeutics, melanoma, and advanced phase 2 and 3 trials, but you know this is something you do very well. So Abstract 2504, it's a phase 1 trial of TIM-3 inhibitor cobomilab immunotherapy and in combination with PD-1 inhibitors nivolumab and dostarlimab. The AMBER Trial that was presented recently, and in full disclosure, both you and I actually are on this abstract. So, what do you think of this abstract? What do you think of the data that is discussed, and how do we contextualize this in relation to what needs to be done in this space?  Dr. Jason Luke: So, I think this is an exciting abstract because it brings forward what may be the next high-priority immune checkpoint to try to target in clinical oncology. To level-set, I think everybody listening will know about PD-1 and CTLA-4 as immune checkpoints. In the last year, we've had LAG-3 come forward as now a standard of care element of armamentarium in melanoma, and we look forward to further studies of LAG-3 and other tumor types as we think it should be a good partner where PD-1 is otherwise approved.  So here now, we hear about TIM-3, which is another negative regulatory checkpoint on a number of different immune subsets. And in this abstract, the antibody targeting TIM-3 was cobolimab. So, TIM-3 is a very interesting molecule. It has, what you might call, pleiotropic effects in the immune system. So, while in the context of this abstract, it was being targeted as another immune checkpoint on T cells, it's important to point out that TIM-3 has other regulatory roles in other immune subsets such as myeloid cells and very particularly dendritic cells, and that's important because it might bring in another element of the innate immune system to try to drive anti-tumor responses. So, it's an exciting target because it might be able to expand the groups of patients who could benefit from immune checkpoint blockade.  So, in this abstract, we see initially the phase 1 data of combining cobolimab, anti-TIM-3 with anti-PD-1 of a couple of different flavors. And what you could take from this abstract is that in the phase 1 setting, the drug was well-tolerated and combined well, and had pharmacokinetic properties that would be consistent with what we'd expect for this kind of a monoclonal antibody. I think we have to marry this abstract, which is really the phase 1 data about safety in pharmacokinetic (PK) to another abstract presented in the melanoma session, which showed an expansion cohort of patients who got cobolimab plus nivolumab or dostarlimab.  And there we did see a 50% response rate, albeit that there was heterogeneity of patients being treatment naïve versus treatment-experienced. So, what I would say to this on a high level is that I think these data are preliminarily exciting, suggesting that further investigation into TIM-3 may be valuable in terms of expanding the population of patients initially in melanoma, but there will data coming soon in lung cancer and in other tumor types with another novel checkpoint. And I think if we think ahead into the future, the question is probably going to end up being, which combinations of checkpoints for which patients. That's pretty exciting to think about. We've seen a lot of data of PD-1 plus other molecules, and I think some future biomarker stratification really will be necessary to know which patient would benefit the most from which of these combos, but for the time being, this is exciting data to see where the field is going to go over the next couple of years.  Dr. Diwakar Davar: Great. And I guess, to your point, one important thing to highlight from the abstract is your point about the role of the different compartments. There was actually a very interesting dose-response relationship with the highest dose of the drug not necessarily being the most effective dose, suggesting that yes, as you escalate, you may have different effects in different compartments, and maybe therefore a broad selection of doses might be required to ensure that you have optimal engagement of the optimal target.  So, the next abstract is Abstract 3007. This is the tumor-agnostic efficacy and safety of erdafitinib. So, we now know that FGFR pathway aberrations are found from 77% of all malignancies, FGFR targets are now U.S. Food and Drug Administration (FDA) approved in cholangiocarcinoma with pemigatinib, infigratinib, and as well with erdafitinib metastatic urothelial cancer. We know that these agents are not necessarily effective tests in 1 tumor type because these alterations have risen in multiple tumor types. So, the RAGNAR trial, looking at this across multiple tumor types, what do you make of the interim analysis result presented by Dr. Loriot?  Dr. Jason Luke: So, I'd say that this is probably the future of targeted therapy. And so, I think that where we have activity in 1 disease, it's very likely we would have activity in others. So, the author has described this as the largest basket trial of a molecularly defined subset that's been pursued to date. There are upwards of more than 200 patients in the study. I think it's really important, as we think about the data, to realize, though, that all FGFR alterations are not exactly the same thing. And so, in this study, they gave erdafitinib to patients with solid tumors of any FGFR altered status. And so that's FGFR1, 2, 3, 4 mutations or gene fusions. And that's a lot of heterogeneity in there actually.  And in this study, there were two-thirds fusions and one-third mutations, mostly in FGFR2 and 3. That will become relevant as we start to think about the results. On a high level, I have to say that it is impressive in pan-cancer fashion, just selecting by FGFR alteration, there's about a 30% response rate observed. I think that no matter what, that's going to be valuable considering these were patients with refractory tumors with 3 lines of prior therapy on median. I think what we need to know more is the breakdown of which specific molecular alteration and FGFR in which tumor types drove most of the benefit.  So, for example, in bladder cancer where erdafitinib is already approved, that's almost entirely an FGFR3 fusion setting. So we know the drug is effective there. And so I think there will be a further breakdown of the data. As it matures more, you really start to tease out, is it really the case that any FGFR alteration can be treated or there are some that really ought to be the high priorities that we really ought to be going after. I think it would be remiss not to also note, however, that while there's excitement about this sort of pan-cancer approach, the current generation of FGFR inhibitors are not exactly the easiest drugs to take.  And so, the in-class, hypophosphatemia and stomatitis really does lead to dose reductions in a lot of the patients. And I think that that's probably really important to emphasize is that despite the pan-tumor activity, there's still a lot of potential in this field to refine further because it's almost certainly the case that if we had less off-target toxicity, so to say, we could improve the efficacy beyond that 30% that we saw here.  All the same, I think this is exciting for the concept of a pan-cancer tumor agnostic sort of approach, and we'll really look forward to more data to come from this study over the next, hopefully, few months.  Dr. Diwakar Davar: And I guess 1 corollary to that is that we now need to start looking for FGFR alterations in multiple tumor types. So, tests, tests, tests. All right, Abstract 3004, phase 1a/1b dose escalation and expansion study of the MDM2-p53 antagonist BI 907828 in patients with multiple solid tumors including advanced, metastatic, liposarcoma. So, we've recently had data of the previously undruggable KRAS, and now we've got previously undruggable p53, for which we now have targets. So, Jason, what do you make of the p53 targeting approach, in this case, using MDM2 and this particular drug from Boehringer Ingelheim?  Dr. Jason Luke: So, I think that this is an exciting abstract exactly for the reason that you mentioned, which is that p53 has been, and unfortunately, to some degree, still remains, one of those holy grails but undruggable targets in oncology. So MDM2, for those who are listening but might not be aware, is a negative regulator of p53. So, the concept here then is if you drug it, you might release p53 to reactivate activity in that pathway, and then p53 being the guardian of the genome, so to say, potentially leading to apoptosis of cancer cells.  And so, this drug binds MDM2 and MDM2 can be amplified as a resistance mechanism in p53 and several tumor types. And so here, they showed data for the early part of a clinical trial investigating the small molecule, BI 907828, but then they focus specifically in liposarcoma, which is a disease known to be an MDM2 amplified. And so, the results were pretty interesting. The toxicity of this kind of an approach, just to note, is really in class. It leads to some gastrointestinal (GI) toxicities as well as hematologic problems, and this goes again for most regulators of the cell cycle will have these effects, whether they're CDK inhibitors or MDM2 or p53 modulators.  But I think what was very interesting, this is a disease liposarcoma where chemotherapy, functionally speaking, has no role. We, unfortunately, give it to some patients sometimes, but it has almost no activity, and they observe that in poorly differentiated liposarcomas, the response rate was about 12%, but the stable disease was quite durable. And so, I think that really is potentially a big deal because this is an orphan disease. It really lacks any other treatment. But as you zoom out from that, if you start to think about targeting amplified MDM2 in other settings, I think the activity that we see here is intriguing, and potentially suggests that we may be coming to a future where we'll have multiple, sort of, orthogonal approaches after reactivating p53. There were actually other abstracts at ASCO Annual Meeting of other molecules that were less mature also along this line.  So, I think, very exciting to take away from this, one, a potential treatment for liposarcoma for all of those patients that anybody listening actually sees, but secondarily this concept of targeting p53, which I think we'll see a lot more of over the next couple of years.  Dr. Diwakar Davar: Excellent. Moving on to the Abstract 3002, this is a phase 1, two-part multicenter, first-in-human study of DS-6000a of an antibody-drug conjugate comprising the anti-CDH6 IgG1 monoclonal antibody that is attached to a topoisomerase I inhibitor payload via a cleavable linker. And so basically, a way in which you can give topoisomerase: (1) TOP1 inhibitor, (2) CDH6-expressing cells. This was studied in advanced renal cell carcinoma (RCC) and advanced ovarian cancer in this abstract presented by Dr. Hamilton. Jason, what do you think of the results and what do you think of this approach in general, this antibody-drug conjugate (ADC) approach using novel targets as well as novel payloads?  Dr. Jason Luke: I think this is one of those that you can't help but be pretty excited about, and I think in the context of the data shown at the plenary session in breast cancer for antibody-drug conjugates (LBA3), I think this is really where the field is going to start to go. So, you mentioned that this is an antibody-drug conjugate that targets cadherin 6 or CDH6, which people will remember from biochemistry class and medical school, or something is a cell-cell adhesion molecule, really a basement membrane protein. So, the concept of targeting it really is just to go after a latch mechanism to get the molecule into the tumor where you want. And CDH expression is very high in renal cell carcinoma, upwards of 80% of samples, also high in ovarian cancer, which is why they chose those 2 tumors to go after.  So, the ADCC, and you described its structure just a little bit, but it's essentially the same backbone as trastuzumab deruxtecan, which we saw this outstanding activity for HER2 and breast cancer on the plenary, with these 8 chemotherapies moieties attached to it, but here now, targeting it instead to HER2, with this molecule now to CDH6. And I think, again, you can't help but be impressed. There were treatment responses on almost every dose level of the dose escalation in this study. There's in fact only 1 patient whose tumor was not, at least, stable disease or a PR, and I think that that just goes to show the power of truly bringing the chemotherapy in a targeted manner into the tumor microenvironment. Responses were heterogeneous. They were not super deep responses per se, but the stable disease was quite durable in the study, and the patients were going out more than 7 months. And again, realizing this is at the lower dose levels as we're increasing the dose and move this in their earlier lives of therapy is likely to be even more effective.  They did show a waterfall plot of the reduction in CA 125 for the patients with ovarian cancer that really looked quite impressive. And given that that's our clinical biomarker that we commonly follow, it may actually even more indicative of the benefit we would see as opposed to resist.  Now, again, there is some toxicity. It is a chemotherapy moiety that's conjugated to the ADCs. So, the most common toxicities were nausea, vomiting, and low platelet counts, but these are kind of toxicities that we're quite accustomed to with chemotherapy. Just to summarize, I think there's a lot of promise for this kind of antibody-drug conjugate targeting, and I think it can only be impressive that they had this amount of activity in the dose escalation of the study. [I] very much look forward to the expansion cohorts in renal and ovarian, which we'll presumably expect to see later this year, early in the next year.  Dr. Diwakar Davar: And as you alluded to, this really was parallel that ASCO, by the standing ovation given to Dr. Modi when she presented the DESTINY04 data of trastuzumab deruxtecan in HER2-low breast cancer, basically now redefining breast cancer from 4 camps, now we have to think of not just HER2 amplified or HER2-high, but also HER2-low. So yes, really have to now rethink how we classify these diseases (LBA3).  So Abstract 2509, the efficacy of anti-PD-1/PD-L1 immunotherapy in non–small cell lung cancer dependent based on CD8 and PD-L1 status. So really Dr. Galon taking us into what he has now described as the immunoscore—really a way of characterizing tumors. A way of thinking about tumors that you've also championed, Jason, in terms of this T cell-inflamed and uninflamed hypothesis. So, tell us a little bit about how these jives with your work and how you would think about lung cancer patients responding and not responding to immune checkpoint inhibitors (ICI) therapy in this context?  Dr. Jason Luke: Yeah. I think the focus quickly here on the immunoscore, so the people are aware of that, I think is really important for diving into these specific results. You have to realize our fundamental underlying predicate for immune checkpoint blockade inhibitor response is that patients have mounted an adaptive immune response. So, CD8 T-cells have gone into the tumor where they elaborate chemokines and cytokines like interferon gamma, which upregulates the expression of PD-L1 in the tumor but also in the surrounding immune cells.  So, you realize that even though antibodies are targeting PD-1, it's really that we're targeting that tumor microenvironment. So, the more robustly we can measure that, and we understand it, the more likely we are to know whether or not the patient is going to benefit. So, this is where the immunoscore comes in. The immunoscore is actually a fairly simple test. It's one slide, immunohistochemistry slide where they can stain jointly for CD8 and PD-L1 on the same slide. And that allows them to do a number of different things beyond just testing the total level of PD-L1. They can test the CD8 density, the PD-L1 expression, but then also the interaction between CD8 T-cells, their distance from each other, from PD-L1 expressing cells, and so on and so forth.  And so really [this] can give us a much more robust analysis of what all is going on in the tumor microenvironment again, off of a single slide. So here then, in this abstract, for patients with non–small cell lung cancer receiving anti-PD-1, they then compared the utility of only PD-L1 testing versus doing the immunoscore. And so, it was actually quite a large set. They had about 250 patients in their analytical set and then split about 150 or 180 or something into the training and validation sets, and they compared the immunoscore against 2 different standard PD-L1 antibodies, the 22C3 as well as the SP263. And what they saw was a high concordance for expression between PD-L1 and the immunoscore.  That's good, because, again, they're measuring PD-L1 in both of those. And so that was a good, sort of, level set. The immunoscore, however, allows them to look to 7 different parameters, again, beyond just PD-L1, as I mentioned. So, CD8 density, interaction, distance, and this kind of thing. Then in these test and training cohorts, they were able to actually split out patients who are PD-L1 positive into further groups, those that were immunoscore low and that were high. And in so doing, they were actually able to sort of dramatically predict the likely progression-free survival on PD-1 checkpoint blockade in those different non–small cell lung cancer groups.  So why is this important? Selection of patients by PD-1 has been very useful in the field of non–small cell lung cancer, but it's hardly a panacea. You're not at all assured your patient is going to do well just because they're PD-L1. And here comes a second assay that can be done in a standard of care setting. So, the immunoscore is a test. You could just order it, and that really does give you much more predictive power about who's likely to do well and who isn't. And I think this test and more broadly multi-spectral imaging is really going to become a core component to how we risk stratify and predict outcomes to checkpoint blockade and lung cancer, but broadly in other tumor types over the next couple of years.  Dr. Diwakar Davar: Okay. Now, moving on from a biomarker for PD-L1 and PD-1 to a setting in which PD-1 was just recently U.S. Food and Drug Administration (FDA)-approved, so I'll give a brief background to the trial that you've actually developed and led. And so, this is KEYNOTE-716, the abstract in question is LBA9500 (late-breaking abstract) 9500, but this is the distant metastasis-free survival (DMFS) data readout. The DMFS, distant metastasis-free survival with pembrolizumab versus placebo in the adjuvant setting for patients with stage IIB or IIC, that is high-risk node-negative melanoma and the data from the phase 3 KEYNOTE-716 study.  So, this data, at least the recurrence-free survival (RFS) data was actually earlier published, you had presented it earlier last year and also more recently this year, but it was published recently in Lancet. And we know that 716 is a study in which, for the first time ever, we have an immune checkpoint inhibitor PD-1 that was studied against placebo with the high-risk node-negative setting in stage IIB and C melanoma, demonstrated a significant RFS benefit in the setting against placebo. And now we have the DMFS readout.  Maybe you could tell us a little bit about both the RFS and the DMFS data, and why this is such an important advance for these patients.  Dr. Jason Luke: Thanks. And I agree this really is a sea change in how we thought about stratification of patients with melanoma, but I think this broadly has implications for other tumor types as well. So, in melanoma, we've historically thought of its involvement of the lymph nodes—stage III as being the high-risk disease, but we also, if you look at the outcomes from the AJCC, we see the patients with stage IIB and IIC, so deep primary lesions, actually have similar bad outcomes as those patients with stage IIIA and IIIB. And so anti-PD1 and adjuvant therapy and melanoma were originally proved for stage III, but having understood that about 5 years ago actually, started to think, well, why not also treat the patients with stage II if they're at similar risk.  And we pursued KEYNOTE-716 as you mentioned, and it read out last year as a positive trial for recurrence-free survival. And the abstract here then was to look at the impact on distant metastasis-free survival. So, while the regulatory consideration for approval, and it is approved and it's available for patients now, was based on relapse, what we really want to be preventing is the development of metastatic disease because presumably that would correlate with the eventual death of the patient from cancer.  So, in the abstract here, we see the first update for DMFS, which also was positive on its first analysis, the hazard ratio at 0.64. And so, again, very similar to the RFS benefit, showing about a 35-36% reduction in distant metastasis-free survival. And this is a theme that we've seen across adjuvant studies in melanoma, all the adjuvant studies in fact, is that the RFS improvement, the relapse-free survival hazard ratio mirrors very closely the distant metastasis-free survival ratio. We saw that again here. I think it just emphasizes that anti-PD-1 immunotherapy is highly effective in melanoma no matter what stage it's in, but rather related to the risk of death for melanoma.  And so this really has a practice changing in the field of melanoma oncology. Patients need to be referred to medical oncology early for discussion around risk stratification and consideration of adjuvant therapy—I think even at the same time that they're having resection of their primary lesion, and it even calls into  question of whether or not we should even fully be doing procedures like sentinel lymph node biopsies any longer, considering we can make the decision to give adjuvant therapy now based on the primary—albeit that's a controversial area of discussion.  And I would just love for this to start to penetrate into other disease settings. We've seen more recently, approval for neoadjuvant therapy in lung cancer and we see in kidney cancer, bladder cancer. We see adjuvant therapy in—I think we're going to see immunotherapy starting to become an important part of the armamentarium in these hard-to-treat cancers, even at the time that perioperatively before or after surgery.  So definitely a major change in the way we're thinking about stratifying patients and emphasizes that you need to get those patients with melanoma in to have that discussion around adjuvant therapy probably at the time of the primary lesion resection.  Dr. Diwakar Davar: And finally, Abstract 2507, single-cell profiling of human heart and blood in patients with checkpoint inhibitor-associated myocarditis. So, this is data from the NGH Group, Dr. Villani and colleagues are presented by Dr. Blum. We know that myocarditis is an uncommon but very serious immune related adverse event (irAE), and here in this particular dataset, this group which has done a lot of underlying work to really uncover the role of certain key phenotypes, cellular phenotypes, in the development of myocarditis it's presenting the data in the context of ICI-related myocarditis. So, what do you think of this data, what do you think of the use of checkpoint inhibitors are now, as you've said, migrated linear in the lifecycle of the patient, what do we need to be thinking about and how does this improve our understanding of both the use of the drug and what we need to be worried about?  Dr. Jason Luke: I think the toxicities of immunotherapy, while, less frequent than, say, chemotherapy, can actually be more disastrous. In the rare patients, we have extreme immune-related adverse events, there is an incidence of actually life-threatening and fatal events. And so, myocarditis, associated with checkpoint blockade, is one of those things that could be seen, and here at ASCO Annual Meeting, we saw a couple of abstracts summarizing the experience from the National Cancer Institute following myocarditis events, and then this abstract in a translational level trying to better understand what is actually going on in terms of the immune response in those myocarditis cases.  And so, I thought this was actually a very interesting abstract. There was only a small number of patients. They had 13 samples from patients who had had endomyocardial biopsies in the context of immune-related myocarditis, and you might say, well, only 13 samples, but fortunately, this is quite a rare event, less than 1% of patients who get immune checkpoint inhibitors. And what they saw was relatively unsurprising, which is that in patients who were having myocarditis, they saw an increase in T cells and in K-cells, as well as activated CD8 and CD4 T-cells.  I think what was very interesting was when they started to dig into what were the phenotypes of the cells and what were the pathways that were turned on. Again, it was not especially surprising to see that they saw increased levels of interferon signaling and immune-receptor signaling as well as motility and adhesion, but this really, I think emphasizes that there are potentially interventions beyond just the general immune-suppression approaches that we give. They could be more nuanced but perhaps more efficacious because sadly, patients do pass away when they develop this. And in their cohort of 13 patients, 3 of those patients died. And specifically, in looking in those 3 patients, they actually saw that all 3 patients had a shared T cell cluster. And they can't exactly say what it is exactly yet, but I think it's very interesting to see that because it suggests that there's probably something about the T cell response in those patients that disproportionately triggered a fatal event.  And if we can understand that better, we then may be able to really tailor our interventions in a way that is more useful. Because, frankly, the way these patients usually present is they show up in the emergency room (ER), and they're seen by an ER doctor who thinks they're having acute coronary. They ship them off to the catheterization (cath) lab. They open him up, and then they get in there, and there's nothing going on. There's no plaque. And so now, all of a sudden, everyone is quite confused. And so, if we had better ways to search for that ahead of time to be aware of it, we might have better interventions because usually what happens right at that moment is everybody gets very confused and starts calling the oncologist, and we start slapping on steroids and other immunomodulatory agents, but sometimes it's late.  So, I think this is a great abstract. It's really starting to preliminary give us an idea of what is the actual biology that underpins these terrible events, and we can hope that we can build off that over time hopefully to eventually come up with better predictors and then obviously better interventions to try to avoid these outcomes in a small but real number of patients.  Dr. Diwakar Davar: Excellent. One other point is you and I are both involved in drug development, and as we start thinking of side effects. Side effects are really on the flip side of responses in drug development. So really 1 point to make of this is that when people start developing side effects rather than, as you say, putting your hands up in the air and waving them around, 1 of the things that we should be doing in drug development is possibly biopsying these patients because we could get new PD insights into how these drugs work, why they work, and particularly which sub-populations themselves they work on, particularly in the early-drug development setting when you oftentimes don't have that many responses.  With that, thank you, Jason, for sharing your insights with us today.  Dr. Jason Luke: Thank you.  Dr. Diwakar Davar: And thank you to our listeners for your time today. If you value the insights that you hear on the ASCO Daily News Podcast, please take a moment to rate, review, and subscribe wherever you get your podcasts. So, thank you for your attention, and we will sign out.      Disclosures:  Dr. Diwakar Davar:   Honoraria: Merck, Tesaro, Array BioPharma, Immunocore, Instil Bio, Vedanta Biosciences  Consulting or Advisory Role: Instil Bio, Vedanta Biosciences  Consulting or Advisory Role (Immediate family member): Shionogi  Research Funding: Merck, Checkmate Pharmaceuticals, CellSight Technologies, GSK, Merck, Arvus Biosciences, Arcus Biosciences  Research Funding (Inst.): Zucero Therapeutics  Patents, Royalties, Other Intellectual Property: Application No.: 63/124,231 Title: COMPOSITIONS AND METHODS FOR TREATING CANCER Applicant: University of Pittsburgh–Of the Commonwealth System of Higher Education Inventors: Diwakar Davar Filing Date: December 11, 2020 Country: United States MCC Reference: 10504-059PV1 Your Reference: 05545; and Application No.: 63/208,719 Enteric Microbiotype Signatures of Immune-related Adverse Events and Response in Relation to Anti-PD-1 Immunotherapy  Dr. Jason Luke:   Stock and Other Ownership Interests: Actym Therapeutics, Mavu Pharmaceutical , Pyxis, Alphamab Oncology, Tempest Therapeutics, Kanaph Therapeutics, Onc.AI, Arch Oncology, Stipe, NeoTX  Consulting or Advisory Role: Bristol-Myers Squibb, Merck, EMD Serono, Novartis, 7 Hills Pharma, Janssen, Reflexion Medical, Tempest Therapeutics, Alphamab Oncology, Spring Bank, Abbvie, Astellas Pharma, Bayer, Incyte, Mersana, Partner Therapeutics, Synlogic, Eisai, Werewolf, Ribon Therapeutics, Checkmate Pharmaceuticals, CStone Pharmaceuticals, Nektar, Regeneron, Rubius, Tesaro, Xilio, Xencor, Alnylam, Crown Bioscience, Flame Biosciences, Genentech, Kadmon, KSQ Therapeutics, Immunocore, Inzen, Pfizer, Silicon Therapeutics, TRex Bio, Bright Peak, Onc.AI, STipe, Codiak Biosciences, Day One Therapeutics, Endeavor, Gilead Sciences, Hotspot Therapeutics, SERVIER, STINGthera, Synthekine  Research Funding (Inst.): Merck , Bristol-Myers Squibb, Incyte, Corvus Pharmaceuticals, Abbvie, Macrogenics, Xencor, Array BioPharma, Agios, Astellas Pharma , EMD Serono, Immatics, Kadmon, Moderna Therapeutics, Nektar, Spring bank, Trishula, KAHR Medical, Fstar, Genmab, Ikena Oncology, Numab, Replimmune, Rubius Therapeutics, Synlogic, Takeda, Tizona Therapeutics, Inc., BioNTech AG, Scholar Rock, Next Cure  Patents, Royalties, Other Intellectual Property: Serial #15/612,657 (Cancer Immunotherapy), and Serial #PCT/US18/36052 (Microbiome Biomarkers for Anti-PD-1/PD-L1 Responsiveness: Diagnostic, Prognostic and Therapeutic Uses Thereof)  Travel, Accommodations, Expenses: Bristol-Myers Squibb, Array BioPharma, EMD Serono, Janssen, Merck, Novartis, Reflexion Medical, Mersana, Pyxis, Xilio  Disclaimer: The purpose of this podcast is to educate and to inform. This is not a substitute for professional medical care and is not intended for use in the diagnosis or treatment of individual conditions.  Guests on this podcast express their own opinions, experience, and conclusions. Guest statements on the podcast do not express the opinions of ASCO. The mention of any product, service, organization, activity, or therapy should not be construed as an ASCO endorsement.     

The RCWL sensor has a lil solder jumper on the back that lets you turn it into "IIC" mode - we tried it out and ... it kinda works! This sensor can be used on an I2C bus, but it doesn't seem to do well if sharing it with other devices. Still, if you have a microcontroller or microcomputer that doesn't have fast GPIO for toggle/pulse or a hardware UART, you definitely can use it for inexpensive sensing. Note that on this QT Py RP2040 we've got the OLED on a different I2C bus which is why it's happily running for hours now. In stock at the adafruit shop! https://www.adafruit.com/product/4742 #adafruit #ultrasonic #python Visit the Adafruit shop online - http://www.adafruit.com ----------------------------------------- LIVE CHAT IS HERE! http://adafru.it/discord Adafruit on Instagram: https://www.instagram.com/adafruit Subscribe to Adafruit on YouTube: http://adafru.it/subscribe New tutorials on the Adafruit Learning System: http://learn.adafruit.com/ -----------------------------------------

Cada vez mais, campanhas publicitárias e obras do cinema e da TV se atentam para a forma que retratam as mulheres. A diversidade de corpos, narrativas e perspectivas se tornou não só um elemento importante para novas histórias, mas motivo de cobrança e expectativa do público consumidor. A expectativa é que as telas reflitam a realidade feminina, sem estereótipos e inspirando mulheres a fazer a diferença. Mas, como saber se o plano está dando certo? No Braincast #450, Carlos Merigo recebe Ana Freitas, Beatriz Fiorotto e Nana Lima, co-fundadora da Think Eva, para uma análise de como essa mudança na comunicação reflete na sociedade - ou se não está mudando nada. E, mais que isso, se estamos presenciando uma mudança verdadeira, ou se ainda estamos muito atrás em termos de inclusão e representatividade. Em depoimentos por áudio, Bia Granja, fundadora do YouPix, e Flávia Durante, fundadora do PopPlus, complementam e aprofundam a discussão. _____ PMI - PROJECT MANAGEMENT INSTITUTE BRASIL Neste programa, você ouviu o primeiro episódio do especial "Profissão Gerente... de Projetos", uma coluna do Braincast em parceria com o PMI. Nessa conversa em dose dupla, recebemos Adriana Barbosa (CEO da Pretahub e Feira Preta) e Michelle Guimarães (fundadora da Fora da Caixa) Cada "novo dia" exige uma nova forma de estar no mercado. E, com as ferramentas, certas, é o gerente de projetos que vai guiar sua equipe e sua empresa pelos desafios desses tempos. Esse profissional reúne ideias e as torna realidade, entregando um projeto de sucesso. Ele agiliza processos, reduz custos e age de maneira estratégica em cada segmento que atua. E há mais de 50 anos, o PMI trabalha para preparar e especializar esses profissionais. O Project Management Institute Brasil é a associação profissional líder em gerenciamento de projetos e oferece certificações e ferramentas para preparar organizações e indivíduos em todas as fases de sua jornada de carreira para trabalhar de forma mais inteligente para que possam ter sucesso em um mundo de mudanças. Mas também para quem quer entrar no mercado, e precisa se preparar. A empresa do futuro já nasceu. E ela com certeza vai precisar de um gerente de projetos. Acesse o site do PMI e saiba tudo sobre as atividades do Instituto: https://bit.ly/3jXH2cZ PMI: Potencializando a Economia de Projetos. _____ ASSINE O BRAINCAST E FAÇA PARTE DO NOSSO GRUPO FECHADO Assinando o Braincast você pode interagir com a gente em grupos fechados no Facebook e Telegram, além de receber conteúdo exclusivo. Faça download do PicPay para iOS ou Android, clique em “Pagar”e procure pelo Braincast, ou então acesse a URL: picpay.me/braincast _____ SAIBA MAIS 3 boas indicações para fechar o programa com chave de ouro. E para abrir novas reflexões da nossa conversa! Análise | Memes ajudam a lidar com a pandemia, diz estudo | Revista Exame Podcast | Além do Meme, com Chico Felitti Livro | "Também com memes se ensina e se aprende história: uma proposta didático-histórica para o ensino fundamental II" - Cíntia Beñák de Abreu | Disponível na Amazon _____ SIGA O BRAINCAST Seu podcast de sinapses sonoras no infinito das ideias está em todas as plataformas e redes. Inclusive, na mais próxima de você. Encontre o Braincast no Instagram, Twitter, TikTok e na Twitch: @braincastpod Entre em contato através do braincast@b9.com.br. Perdeu o Qual É A Boa? Encontre todas as dicas da bancada nos destaques do nosso Instagram. _____ O Braincast é uma produção B9 Apresentação: Carlos Merigo Coordenação Geral: Ju Wallauer, Cris Bartis e Carlos Merigo Direção criativa: Alexandre Potascheff Apoio à pauta e produção: Hiago Vinicius Edição: Gabriel Pimentel Identidade Sonora: Nave, com Direção Artística de Oga Mendonça Identidade Visual: Johnny Brito Coordenação Digital: Agê Barros, Débora Stevaux e Gabriel Castilho Atendimento e Comercialização: Rachel Casmala, Camila Mazza, Greyce Lidiane e Telma Zennaro

Para 11 em cada 10 brasileiros, "meme" é praticamente sinônimo de internet. Hoje, é praticamente impossível navegar um dia inteiro pelas redes sociais, sem se deparar com um desses posts feitos para viralizar, chocar e transmitir informações (verdadeiras ou falsas) através do riso. O humor é a ferramenta mais democrática na internet, todo mundo pode fazer e, principalmente, compartilhar. Mas alguns têm despontado com mais destaque do que outros. No Braincast 449, Carlos Merigo recebe Marko Mello e Luiz Hygino para um papo com João Miguel Alves de Moura e Silva e Murillo Prestes, do Melted Videos, página que já acumulou milhões de seguidores e fechou grandes negócios, a partir de seus memes. Quem bate o olho num meme, consegue entender como funciona. Mas como ganhar dinheiro com a ferramenta mais usada (e menos valorizada) da internet? _____ PMI - PROJECT MANAGEMENT INSTITUTE BRASIL Neste programa, você ouviu o primeiro episódio do especial "Profissão Gerente... de Projetos", uma coluna do Braincast em parceria com o PMI. Quem participou dessa conversa foi o Dairton Bassi, CEO da Agile Trends. Cada "novo dia" exige uma nova forma de estar no mercado. E, com as ferramentas, certas, é o gerente de projetos que vai guiar sua equipe e sua empresa pelos desafios desses tempos. Esse profissional reúne ideias e as torna realidade, entregando um projeto de sucesso. Ele agiliza processos, reduz custos e age de maneira estratégica em cada segmento que atua. E há mais de 50 anos, o PMI trabalha para preparar e especializar esses profissionais. O Project Management Institute Brasil é a associação profissional líder em gerenciamento de projetos e oferece certificações e ferramentas para preparar organizações e indivíduos em todas as fases de sua jornada de carreira para trabalhar de forma mais inteligente para que possam ter sucesso em um mundo de mudanças. Mas também para quem quer entrar no mercado, e precisa se preparar. A empresa do futuro já nasceu. E ela com certeza vai precisar de um gerente de projetos. Acesse o site do PMI e saiba tudo sobre as atividades do Instituto: https://pmimg.org.br/blog/a-economia-baseada-em-projetos-o-pmi-de-cara-nova/. PMI: Potencializando a Economia de Projetos. _____ ASSINE O BRAINCAST E FAÇA PARTE DO NOSSO GRUPO FECHADO Assinando o Braincast você pode interagir com a gente em grupos fechados no Facebook e Telegram, além de receber conteúdo exclusivo. Faça download do PicPay para iOS ou Android, clique em “Pagar”e procure pelo Braincast, ou então acesse a URL: picpay.me/braincast _____ SAIBA MAIS 3 boas indicações para fechar o programa com chave de ouro. E para abrir novas reflexões da nossa conversa! Análise | Memes ajudam a lidar com a pandemia, diz estudo | Revista Exame: https://bit.ly/3NUgMxG Podcast | Além do Meme, com Chico Felitti: https://spoti.fi/376fvmx Livro | "Também com memes se ensina e se aprende história: uma proposta didático-histórica para o ensino fundamental II" - Cíntia Beñák de Abreu | Disponível na Amazon: https://amzn.to/3r9xjnR _____ SIGA O BRAINCAST Seu podcast de sinapses sonoras no infinito das ideias está em todas as plataformas e redes. Inclusive, na mais próxima de você. Encontre o Braincast no Instagram, Twitter, TikTok e na Twitch: @braincastpod Entre em contato através do braincast@b9.com.br. Perdeu o Qual É A Boa? Encontre todas as dicas da bancada nos destaques do nosso Instagram. _____ O Braincast é uma produção B9 Apresentação: Carlos Merigo Coordenação Geral: Ju Wallauer, Cris Bartis e Carlos Merigo Direção criativa: Alexandre Potascheff Apoio à pauta e produção: Hiago Vinicius Edição: Gabriel Pimentel Identidade Sonora: Nave, com Direção Artística de Oga Mendonça Identidade Visual: Johnny Brito Coordenação Digital: Agê Barros, Débora Stevaux e Gabriel Castilho Atendimento e Comercialização: Rachel Casmala, Camila Mazza, Greyce Lidiane e Telma Zennaro

In today's episode of The Hormone Prescription Podcast, we're joined by Dr. Keesha Ewers to discuss how energy healing can impact your hormones. We'll be discussing how past childhood trauma can have a lasting impact on your health as an adult, as well as the benefits of energy healing modalities such as yoga and meditation to hormone balance.   Dr. Keesha Ewers is board certified in functional medicine and Ayurvedic medicine, a Doctor of Sexology, trauma-informed psychotherapist, family practice ARNP with a specialty in integrative medicine, a conscious dying doula, and the founder and medical director of the Academy for Integrative Medicine Health Coach Certification Program.   Keesha has been in the medical field for over 30 years. After conducting the HURT Study in 2013 (Healing Un-Resolved Trauma), she developed the HURT Model for understanding how past childhood trauma impacts adult health. This led to the creation of the Healing Trauma Through the Chakra System online program and the You Unbroken online program for patients to heal their trauma and the Mystic Medicine deep immersion healing retreats she leads at her home on San Juan Island, WA.   In this episode you'll learn: -How trauma can impact your hormones -The benefits of energy healing for hormone-related issues -How yoga and meditation can help to heal trauma -What you can do to start healing your own trauma   We hope you enjoy this episode! Be sure to subscribe to The Hormone Prescription Podcast.  And don't forget to leave us a rating and review if you enjoyed it!   [00:54] We are gonna talk about something today that you might think doesn't have anything to do with hormones, but it does. And we're going to draw the line between the two for you and help you understand why vibration has so much to do with your hormones and vice versa.    [01:50] Dr. Keisha Ewers is a board certified in functional medicine and IIC medicine. She's a doctor of sexology trauma informed psychotherapist family practice, a N R P with a specialty in integrative medicine. Al​​so a conscious dying doula and the founder and medical director of the academy for integrative medicine, health coach certification program. Keisha has been in the medical field for over 30 years. And after conducting the hurt study in 2013, Hurtt stands for healing, unresolved trauma.    [03:05] She's also hosting the upcoming summit on vibrational medicine, which we'll have links to in the show notes, healing with vibration summit, and she's got special interest in expertise as well. In fact, I was thinking of all the things I know you've done since that bio was written.    [03:36] We are made up of energy sound travels, you know, in waveforms, light travels in wave forms. The way that our heartbeat is in the form, our E EEG from our brain waves forms, the ocean comes in and waves and goes out and tides, right?    {04:33] And so everything's vibrations, we're we as our human organism in the context of the earthly environments that we're in, it's all vibrations. And so how those vibrations impact each other is going to really have a lot to do with our health, our mood, our longevity, like all of it is affected with how we're vibrating.    [05:45] The perception of fear will start to set off a whole cascade of hormone messenger chemicals in your body that alert the body, how to vibrate, right? So those adrenals need to get to work. Cortisol goes through, this is a vibratory quality. So vibrational medicine is really becoming aware of how you're vibrating. Like every thought, every feeling has its own vibration.    [07:09] Yes. Thank you for that explanation. And yeah, I think as you were talking, I was thinking, I think everybody's familiar with, well, radio waves, the, if that's a wave form, right. But I don't think they think of us as human.    [08:02] And then right when I turned 30, I was diagnosed with rheumatoid arthritis, and it was this fascinating sort of overnight change. That's how my patients describe it too. Like all of a sudden I'm sick, which actually isn't accurate. The body's been trying to get your attention for a long, long time, but how we are with ourselves, you know, it's, it's like we definitely have to kind of all into the pothole before we wake up.    [08:57] And, and the doctor that was seeing me asked, you know, do you have a family history of autoimmune disease? And I remember thinking about that and saying, yeah, I think, I think my grandfather had it and had rheumatoid arthritis and was in a wheelchair at the end of his life with it. He died before I ever knew him, his fifties, which is where I am right now is in my fifties. And she said, well, that's what you have.    [09:43] And I just remember saying, well, hang on, hang on. I'm very, very disciplined. I make my own food. I'm very healthy, you know, is there anything else? And she just said, no, it's genetic. You know, just kinda like closing the book, putting it on the shelf. That's the end of the discussion.    [10:31] And what I just read was so interesting and revolutionary to me, you know, it was like, we're not all the same. We have different ways. We're supposed to feed in water and take care of ourselves. There's no one dietary protocol that's right for everybody. And that, by the way, autoimmune disease is undigested anger.    [11:27] I am attacking myself. And so I thought, when was the first time I wanted to die?  I don't have any clear cognition about wanting to die right now. You know, I don't want to die. So I started going backwards asking that question and I found this little 10 - year old girl version of myself who was being sexually abused by the vice principal of the elementary school that I was attending.   [12:16] I have a stomach ache, you know, and, but I didn't know the word sex, you know, I didn't know the word molest or abuse. Like I didn't know any of the language that was attached to this. And really, I thought it must be because there was something inherently wrong with me. And so when I started looking at that version of myself from this 30 - year old perspective, I went, oh this has to be connected. Like it has to be.   [13:35] Yeah. Thank you for sharing all of that. And um, you know, I know I share part of your story and a lot of women listening do and a lot of women, you know, it's not okay for us to be angry. We're told.    [14:04] At some point that has to be digested. Right. And then digested, and we're taught that anger is bad. It's a negative emotion as a vibrational quality in the whole law of attraction world too. Right. And that's another one that I go, oh no, like you have to let your emotions digest properly and not judge them. And then they can move through.    [14:38] And so the entire idea of emotions being their vibrational energies, they are right. And so they have to be digested. So what modalities might you have used, or you've used with clients or might be talked about in the vibrational health summit?    [15:17] So in the hurt model, healing, unresolved trauma model that emerged from my work, I show, you know, first you have this event and, and we have capital T trauma have lower case T trauma and everybody's had trauma. So not everybody's had capital T trauma. The kind that we're talking about when we're talking about sexual abuse, but you can have trauma that is like tripping in front of the entire class in the cafeteria and, and everyone laughs at you or missing the spelling word and the, or not being able to get to the top of the rope and the presidential challenge in front of everyone. Like all of these.   [16:32] So, you know, it's this really interesting experience to be a child and to have all these little, little tiny experiences throughout the, the jungle of childhood where you didn't have maybe a well attuned, securely attached caregiver who was attuned to you and help you, you navigate. So our brains are not fully developed till we're 26 years old and we don't have our prefrontal cortex online yet.    [17:29] So it's going to be like, everyone's so different and how you create the belief and the behavior pattern that goes with whatever your capital T your lower case T traumas are. Then that's how we lock it. It really does. Like, so sometimes energy workers will do like chakra work with somebody, and they'll feel really good, but then they still have the button that gets pushed. Right.   [18:20] Then they're back to the races again, that just the next time. And so with the hurt model, what I show is, you know, how that button gets created, that get pushed all the way through your adult life, where at first you have the event, then you have a feeling, okay. So if we use my sexual abuse, it's an easy one to track.   [19:10] So you make up a meaning to whatever it is that is happening. Right. And for me, the meaning was people that say, they're in charge and want to protect children, probably can't be trusted. You know, like it's a lie. And so I have to, my belief was I am going to have to be perfect to survive this.    [20:03] I actually have never met anyone with an autoimmune disease that does not have perfectionism in there. And so that's a very untenable way to live your life, to think you always have to be perfect. I was on that road until I was diagnosed with an autoimmune disease, because it was governing everything. I drove myself so hard. So, and it came from sitting in that little desk.    [20:58] And we have to learn how to do that internally. So I start there because if you feel like your safety or survival is constantly on the line, subconsciously nothing else you do is ever going to work. Like you can fix your microbiome until the cows come home and keep going back to those adrenals, and they'll keep turning over, right? Your hormones will never get balanced because you keep having this survival issue.   [22:19] And what, what happens is if you think someone's going to come, if you just care enough, then someone will pay attention to you. That's how we get connected to narcissists. That's how we get into codependent relationships like that does not work. You have to become the parent to you that you always needed. And so I will teach you how to do that. Like how to repair that attachment, how to attach to yourself, how to become grounded, safe, and secure inside your own system. So then you're resonating a vibration that magnetizes others like that to you, right then you're at a higher level of relating. It's not need based.   [23:04] Yeah. So your vibe shifts your vibration and then the law of attraction can bring you what you want. Not what you don't want for a lot of us who say it doesn't work. It's because we have undigested anger.    [23:23] There's a child part in there that's resentful and frustrated and disempowered and angry and your adult self, maybe have the spiritual, the bypass part, right. That can radiate out love and compassion and want to attract with the adult part once. But you have to actually heal that child part because she's in the background screaming.   [23:52] Yeah. It's a really interesting dynamic for people that have been doing a lot of work and are waking up and exploring consciousness and maybe are, you know, into yoga, action, prayer. And they, they forgive, and they go into the law of attraction from their adult brain. But they've bypassed it. It's like building a school on a trash heap. Right?    [24:55] You know what you're talking about so much reminds me of a lot of the 12-step work, which is kind of the first level of addiction recovery, whether it's Overeaters anonymous, alcoholics and anonymous, whatever your thing is anonymous. And basically it is fake till you make it behavior change.    [25:38] One of the things I love about summits is connecting to people and, and the interviews, right. It's just so amazing. So I loved rolling MCRA interview. He's the researcher that for heart math, and you know, really talking about this entrainment that we have with each other and ourselves, you know, vibrationally that we're all in like what Rupert Shere calls the morphogenetic field, and we're influencing it.    [26:20] So you guys are going to have to go look at the summit, and you can see that  we will have the links in the show notes. And I also wanted to ask you because since the last time you were on the podcast, didn't you haven't you completed or in the process of doing your ministerial training?   [26:49] Yeah. I've been doing a master's in divinity. Yeah.   [26:52] Yeah. How has that changed or informed the work that you do?   [26:57] Went into it because I was starting to notice an up and what a couple of Princeton researchers have called deaths of despair in our culture and deaths of despair are overdoses suicides from a variety of different ways and means, and non-alcoholic catty liver disease. And you know, we do have a lot of that and this was pre-pandemic when I started and this was on. Right. And what I started noticing is as this uptick is going up, we also have an uptick in narcissistic personality disorder diagnoses.    [28:04] Right. And at that time again, pre-pandemic, I was a little worried about the lack of community. Maybe people were experiencing it when they didn't have a synagogue or a mosque or a church or a temple, you know? And I thought, where is that getting replaced? Is that why there's so much of this increase in narcissism, an increase. And so I was looking at, at the research of the narcissistic epidemic and what was being shown to be at the root of that.    [28:53] So I went in wanting to really explore that, like what's the role of divinity in this? How do we help people reattach again, it's attachment trauma in my mind to source to their own divine source, you know? And instead of needing it from out here, can they find it here? Can they reconnect to that? That has been my interest in what I was up to. And so I think it informs my work.    [29:48] Yeah. So I have to ask you on this topic or your thoughts on the use of psychedelic and other medicines that may not be mainstream for people to heal these really core, like you said, existential attachment wounds.   [30:04] Right? Yeah. So we tend to like to start and stop the conversation with parents and parent-child bonding. And you know, like it's much bigger than that, right. As I just mentioned, right. And now post pandemic, there's also the bond of the community broken in the way. Right? And so I am an M DMA certified AED psychotherapist. I've trained for 10 years in the use of wa Huma with a teacher in Peru, initiated wa Humira or medicine woman.   [31:11] And so I looked at so many studies from different religions, and it turns out that plant, the use of plant medicine is head and shoulders above anything in efficacy for reducing gut anxiety and to reattaching us to source like we get our left brain out of the way that says that everything has to be proven. We have to see it, feel it, touch it, smell it, taste it, or it doesn't exist and allow the right brain to come forward with the opposite of that.   [32:08] Now take a little nap. You'll be required later when it's time to balance the checkbook. So, you know, uh, you're not going to be killed. You're not going to go anywhere for good, but just, just come to sleep for a little while, you know, and it, and it allows you to get in touch with a lot of its dead. After you go through childhood with your imagination, like the right brain, the ability to be able to get into energy flow, to feel vibratory changes too, you know, so plant medicine assists in that.   [33:01] But if you are not integrating, which takes a skilled therapist to work with you to do this, you know, to give you how to integrate that, then all it is a cool experience. That then means nothing. And I, it doesn't heal you, it doesn't help change anything. So you have to go through like that hurt model and be able to apply it, you know, to helping with attachment trauma, whether it's you feel like you've been betrayed by life or God or the culture or the government or your parents or your spouse, you know, or yourself, and, you know, really heal that and integrate what comes through   [34:24] Yeah. Thank you for sharing that. Yeah. I would, I agree with that. The integration is everything. Yeah. And it's often missing. Yeah. With the way we've, McDonaldized a lot of these medicines.   [34:38] I mean, I'm seeing on Facebook now that you can actually order a ketamine box and just do home therapy. Right. Where, so you're taking the substance by yourself.   [35:15] How does somebody find someone who's expert at being an integration coach? Cause that's not a skill set that most standard therapists, psychotherapists or family therapists have, how do they find someone?   [35:30] I was certified through maps, a similar disciplinary approach to psychedelic research and studies, and they emphasized most of the training was integration. So it's not like, um, so if you get certified with maps, that's a good one because it's all about the integration. So I would say that's probably a good place. You know, these things aren't legalized yet. Right?   [35:57] So people can't advertise. I mean, I've come out, and I've been talking on summits and saying, yeah, like I run groups, right. So people can contact me, but it's not something where the California C I S is, you know, has a psychedelics research program. Like I said, John's Hopkins has tons of money now that they have allocated toward this research. So we're still in that research stage of bringing out enough science to sink a ship many times over for the FDA to finally go, oh, you know, so MDMA is in its third round of FDA trials.    [36:58] Yeah. So eventually you know I have been legalized in the state of Oregon, but right now they're in this, the position of creating oversight, you know, like pulling all of like, what's the infrastructure going to look like?    [37:30] Great. Well, thank you so much for sharing that and for your transparency, I think that it's, it speaks a lot to, people need to hear this, that practitioners who are credentialed, use these things help with these things and that they are available.    [37:55] Yeah. So let's dive back to the summit, and then we're going to wrap up the podcast, but I just will have the link in the show notes where you can find out more, you can see all the experts, what they're talking about, any last words about the summit that you wanna share,    [38:11] That this is an innovative and unique way of opening up a perspective. A lot of people haven't maybe spent too much time in. And so I would just really encourage you to listen to, it goes from like the vibration is how to organize your home environment. I did a talk on boss, which is the sister science of yoga and IIC medicine, which is where I came from. And you know, like what are some very easy things you can do inside your office and home to have, do the energy move in a way that helps you be healthy and abundant and happy, right?    [39:11] Thank you so much. And as you're talking, I'm realizing, I promised at the beginning name, we were gonna talk about vibration and hormones, which we didn't get to, but everybody listening, Dr. Keisha is doing a masterclass with participants in one of my programs when we get done. So we will talk about that.   FREE Online Summit hosted by Dr. Keesha Ewers: Healing with Vibration 2.0 will provide you with all the information you need to understand: Yourself (& everything else) as energy Vibrational healing modalities & how they work Techniques you can start implementing today How non-beneficial energies cause dis-ease Links between immune dysfunction & emotions The energetics of healing cancer Frequencies that can access & address unconscious trauma How to heal leaky boundaries with yourself & others The world's leading experts on vibrational health share the science behind practices that can awaken energies in you that bring resilience, vitality, and joy! CLICK HERE to register: https://healingwithvibration.byhealthmeans.com/?idev_id=25286   Q & A Episode each month Submit your questions here (leave me a voicemail): https://bit.ly/AskDrKyrin   Join The Hormone Bliss Challenge  FEEL ENERGIZED, SEXY & CONFIDENT IN YOUR BODY AGAIN... IN JUST 5 DAYS. Discover How To Balance Your Hormones & Jumpstart Your Metabolism So That You Can Lose Weight & Regain Energy! CLICK HERE: https://bit.ly/hormonebliss

It is a testament to her life that the institutions she founded—IIC, National School of Drama, and the township of Faridabad—still exist. ----more---- https://theprint.in/opinion/meet-the-indian-freedom-activist-who-didnt-want-her-legacy-to-survive-kamaladevi/902852/?amp

In Episode S4E5, we have as our guests two individuals who are distinguished by their work with the Industry IoT Consortium (IIC). Bassam Zarkout—Executive Vice President IGnPower Inc. and the Chief Editor of the Industrial IoT Artificial Intelligence Framework (IIAIF). Wael Diab—Chair IIC Industrial AI Task Group and Secretary IIC Steering Committee. About the IIC Since its founding in 2014, the IIC has helped build a technical foundation for the Industrial IoT. They work to help organizations take advantage of IoT technology and achieve positive outcomes. They are focused on driving technology innovation that fosters business transformation. Their services are targeted toward helping members drive business value in the core verticals of IT, Networks, Academia & Research, Manufacturing, Energy & Utilities, and Healthcare. They provide best-practice frameworks and liaisons with Standards Development Organizations. Topics we cover: The purpose of the Industrial IoT Artificial Intelligence Framework Examples of some applications for AI in IIoT The value proposition AI can enable in next-generation industrial IoT (IIoT) systems Perceptions regarding ethics, confidence, trustworthiness of AI About our guests: Bassam Zarkout is the Chair of the Digital Transformation working group at the Industry IoT Consortium. He is an Ottawa-based technology executive with 30+ years of experience in technology organizations in Canada, the US, and Europe, including 8 years in executive C-positions, mainly as CTO. Bassam is the founder of IGnPower, an IIoT and AI strategy consulting practice. He has authored and contributed to multiple peer-reviewed papers and frameworks covering Digital Transformation, Industrial AI, Trustworthiness, Data Protection, and IoT Security. He is also a veteran of the Information Assets Governance space, including Electronic Records Management, RegTech, Content Management, and Electronic Discovery, and has led research with US DoD in the area of assisted security and privacy classifications of content. Wael Diab is a business and technology strategist with over 885 patents to his name in the fields of networking and ICT. Wael has BS and MS degrees in EE and BA in Economics from Stanford, and an MBA with honors from Wharton. He is a published author, having authored the book Ethernet in the First Mile: Access for Everyone. In 2011, Wael was recognized by the David Packard Medal of Achievement and Innovator Award for his leadership in Green Technology. He has been active in standardization and related activities for two decades. He chairs ISO/IEC JTC 1/SC 42, the international standardization committee on artificial intelligence (AI). Wael is also chairing the AI track of the 22nd Global Standards Collaboration meeting (GSC-22). Don't miss this opportunity to learn more about AI in security and IIoT applications.

With the help of special guest host Lisa Mol we talk about the impact of war and conflict on heritage: from stone research and training initiatives and all the way to saving Ukrainian digital heritage en-masse. We're also joined by Emma Cunliffe from Blue Shield, Sarah Stannage from IIC, and Richard Mulholland from Northumbria University as we discuss what's being done already and try to figure out how we can all help. 00:01:31 Explosives meet geology 00:05:50 Training over intervention 00:10:58 Priorities in war and its aftermath 00:16:13 Interview with Emma Cunliffe at Blue Shield 00:27:13 When is damage itself heritage? 00:32:08 Saving Ukraine's digital heritage 00:37:58 Looting 00:43:44 Interview with Sarah Stannage from IIC 00:50:13 Other funding, support and resources re: Ukraine 00:51:21 Addendum time! 00:53:05 Comfort-a-Conservator 00:55:59 Interview with Richard Mulholland 01:07:45 Go forth and do good Show Notes: - Heritage in the Crossfire: https://www.heritageinthecrossfire.com/ - Get in touch with Dr Lisa Mol: https://people.uwe.ac.uk/Person/LisaMol - S01E10 Salvage: https://thecword.show/2017/07/05/s01e10-salvage/ - Blue Shield International: https://theblueshield.org/ - Blue Shield UK: http://ukblueshield.org.uk/ - Emma's blog entry about her new book: https://boydellandbrewer.com/blog/heraldry-and-genealogy/safeguarding-cultural-property-in-the-1954-hague-convention-all-possible-steps/ - ‘Safeguarding Cultural Property and the 1954 Hague Convention' by Emma Cunliffe and Paul Fox: https://boydellandbrewer.com/9781783276660/safeguarding-cultural-property-and-the-1954-hague-convention/ - Examples of churches in Europe left in ruin after WW2: https://en.wikipedia.org/wiki/Category:Ruins_of_churches_destroyed_during_World_War_II - Frederik Rosén's publication list (as mentioned by Lisa): https://www.heritageconflict.org/frederik - Saving Ukrainian Cultural Heritage Online (SUCHO): https://www.sucho.org/ - Iraq Museum Looting 15 Years On: https://www.sydney.edu.au/news-opinion/news/2018/04/10/iraq-museum-looting--15-years-on.html - IIC Opportunities Fund: https://www.iiconservation.org/about/awards/opportunities - IIC official Ukraine update page: https://www.iiconservation.org/content/how-ukraine-moving-protect-its-cultural-heritage-updated-22-march-2022 - Nordiska Museet fund for Ukrainian museums: https://www.nordiskamuseet.se/artiklar/ekonomisk-insamling-att-radda-ukrainas-kulturarv - Call for supplies for Ukrainian heritage protection: https://www.icon.org.uk/resource/supplies-needed-to-protect-ukraine-s-cultural-heritage.html - Icon's Support for Ukraine page: https://www.icon.org.uk/resource/support-for-ukraine-conserving-cultural-heritage.html - Icon's Ukraine event on March 24th 2022: https://www.icon.org.uk/events/ukraine-supporting-cultural-heritage-and-conservation-colleagues.html - About Richard's work: https://research.northumbria.ac.uk/VisualMaterialCultures/?page_id=534 - Richard's paper in Studies in Conservation: https://www.tandfonline.com/doi/epub/10.1080/00393630.2022.2025706?needAccess=true Support us on Patreon! http://www.patreon.com/thecword Hosted by Jenny Mathiasson, Kloe Rumsey, and Lisa Mol. Intro and outro music by DDmyzik, used under a Creative Commons Attribution license. Made available under a Creative Commons Attribution-NonCommercial 4.0 International license. A Wooden Dice production, 2022.

The Mechbay does some hobby roundup talking about how to stay motivated when you are between deployments. They talk the new wolfhound IIC from catalyst, shilones, and a whole lot of hobby progress. Keeping that reactor fired up takes work so don't let the flame die out.Listen to our interview on Miniature Wargaming Labs Here!Battletech Event Calendar DocTalk with the Mechbay and fans on their DiscordIf you like what you hear or have request for what you would like to hear next, send them a shout at themechbaypodcast@gmail.com or on FacebookYou can support them at Patreon and get your name and mech shouted out in episode.Our Main Segment is proudly brought to you by Fortress Miniatures and Games.Our Hobby Progress Section is proudly brought to you by Ariesgamesandminis.comPatron SupportersArchonsCataphract 40 piloting Nightstar NSR-9JStefan Stahlkater "McKenna" piloting Warwolf HTristan "Jackal" Lawrence piloting Cyclops 10Q modifiedMechwarriorsDuncan RhodesChad "Storm" Evans piloting Hatchetman HCT-8SPC "Creature" McKenna piloting Piranha PRA-4Chris "Kazrok" Miller piloting Thug 12KDenham "Eclipse"  piloting ShadowHawk SHD-2HJared HahnRex "Redneck" Rawhide piloting Orion-VACadetsJohn HaynesMatt LeBaronMitch "Minotaur" Grant piloting Thunderbolt 5SEHarris "Ramshackle"  piloting Cataphract CTF-4LMetalEdJohn GarnierRichardKZDavidZach Torrence "Metalzarak" piloting Black Hawk HJestyTravis GistOutro by Marcelo Etiene

Inverco ha presentado su informe anual donde refleja que el volumen de activos de las instituciones de inversión colectiva (IIC) se podría situar este año en los 672.000 millones de euros. Su presidente Ángel Martínez-Aldama nos ha desgranado los datos en La Entrevista Capital. Además comentamos la actualidad económica y política en La tertulia con - José Ramón Álvarez, Profesor de la Escuela Técnica Superior de Ingenieros Industriales y con Ignacio García de Vinuesa, economista. Preapertura de las bolsas europeas con Glen Chapman, Director de Estrategia de Renta Variable y Crédito de Banco Sabadell.

Listen to a soundcast of the December 2 and 3, 2021, FDA approvals of Rituxan (rituximab) plus chemotherapy for pediatric cancer indications, and Keytruda (pembrolizumab) for adjuvant treatment of Stage IIB or IIC melanoma.

El poder fructificador de la Sangre de Jesús (II) - César Castellanos

All businesses need to enhance their Corporate Social Responsibility so they can cultivate good relations and contribute to the benefit of the community at large. Improving their image is an added bonus. In this interview with host Phil Pelucha, Philip Webb talks about helping firms manage their Corporate Social Responsibility. Philip is the founder and CEO of Investors In Community, which is a digital platform enabling companies across the UK to donate, volunteer, and gift to charity and community initiatives to which they feel connected. It is now more important than ever to be doing everything we can to improve the world we live in for future generations; IIC provides the perfect opportunity to build a movement for good. Charities and Individuals can use his platform for free, meaning 100% of the money donated through this platform stays in the charity sector. Philip started his career working for IBM UK as a hardware specialist. He has since published 3 business books and is the legal custodian of the research from Stanford University of the SWOT analysis.   Contact our guests https://www.linkedin.com/in/philipwebbtam/ (Philip Webb LinkedIn) https://linktr.ee/iic (Link tree with all Links - get involved) Contact our Host https://www.linkedin.com/in/philippelucha/ (https://www.linkedin.com/in/philippelucha/) http://billionairesinboxers.com/ (http://billionairesinboxers.com/) https://billionairesinboxers.com/starter-package/ (https://billionairesinboxers.com/starter-package/)