Podcasts about Checkmate

Today, we cover ASCO 2025 in the genitourinary space, specifically bladder and renal cancer. Dr. Enrique Grande, a renowned oncologist and Program and Clinical Research lead of MD Anderson Cancer Centre, Madrid, joins us. This is a mega episode where we cover AMPLITUDE, JAVELIN MEDLEY, CHECKMATE 901 and NIAGARA, advancing urothelial cancer care; SEAR 02 and the CReST trial, pushing boundaries in bladder cancer; CHECKMATE 214; LITESPARK-005 and LITESPARK-004, showcasing belzutifan's promise; and KEYNOTE-564, adjuvant therapy for kidney cancer. Stay tuned for an insightful conversation on how these trials may be transforming patient outcomes!Studies discussed in the episode:CHECKMATE 901NIAGARACHECKMATE 214CREST trialSEAR 02LITESPARK 004/005AMPLITUDEJAVELIN MEDLEYFor more episodes, resources and blog posts, visit www.inquisitiveonc.comPlease find us on Twitter @InquisitiveOnc!If you want us to look at a specific trial or subject, email us at inquisitiveonc@gmail.comArt courtesy of Taryn SilverMusic courtesy of AlisiaBeats: https://pixabay.com/users/alisiabeats-39461785/Disclaimer: This podcast is for educational purposes only. If you are unwell, seek medical advice.Oncology for the Inquisitive Mind is recorded with the support of education grants from our foundation partners Pfizer, Gilead Pharmaceuticals and Merck Pharmaceuticals. Our partners have access to the episode at the same time you do and have no editorial control over the content. Hosted on Acast. See acast.com/privacy for more information.

In this episode of Around the School Table, host Steve Davis talks with Craig Ainsworth from Westport Public School about how a modest chess program in a low socio-economic school achieved elite educational outcomes over 18 years. Far from just a lunchtime club, Craig’s program developed students’ physical control, emotional intelligence, intellectual stamina, and creative thinking—all through the game of chess. Ainsworth shares that success wasn’t about innate giftedness, but about effort and process. Using a structured approach—such as the KM-PPS framework (King safety, Material, Pawn structure, Position, Space)—students learned to handle pressure, make strategic decisions, and apply consistent critical thinking under stress. Chess became more than a game; it was a vehicle for building resilience and a growth mindset. The program had broad academic impacts, boosting students’ performance in both maths and literacy. Notably, it also shattered stereotypes: many of the top players were athletic or quiet students who, through chess, discovered untapped cognitive strengths. Craig emphasises that coaching was not passive—it required active engagement, questioning students about their decisions, and creating an environment where learning was mutual. A key to the program’s longevity was its self-sustaining culture of mentoring. Elite players trained the next cohort, creating a legacy of peer-led excellence. Even though the program paused when Craig left in 2018, its ripple effects are seen in students now pursuing high-level studies and careers. When asked why chess still matters in the age of AI, Craig affirms that machines can analyse but not create. It’s human creativity, developed through tools like chess, that remains irreplaceable. This episode is a testament to how traditional games, paired with intentional teaching, can unlock transformative educational experiences—especially in places where they’re least expected. See omnystudio.com/listener for privacy information.

The globalist resistance, pro-America, media has been completely exposed as nothing more than a new form of mockingbird press. The big patriot leaders are in unison calling for the end of “third world immigration” and even “non-white immigration,” becoming the very thing the left accused them of all along - while ignoring the fact that Asians, for example, commit little crime, use few drugs, and are some of the top earners and contributors to the country. All the hopes and dreams of “promises made, promises kept,” are evaporating in real time, with few able to further justify the increasingly obvious: the downfall of the Republic has been monetized and archetypically framed. With riots all across the country, fears of a black and white racial war have instead manifested as Mexican and American; the fear of outright civil war has manifested as a problem-reaction-solution of absolute information control and military martial law in the name of defending the country. Now the “No Kings” movement has nationwide protests planned for June 14th, 2025, the day of Saturn. Rather than arresting the organizers behind that, and the riots via the communist Indivisible, the AG has instead sued a coffee shop for antisemitism. The protests are meant to resist the massive military parade and presidential birthday parade in Washington on the same day. Don't like it? You will be met with “very big force,” says the President, if you don't like his “big parade.” BIG beautiful bill anyone? Not even Roman emperors held military parades for their birthdays, but they did hold them for victories in battle. So either the Trump camp is totally delusional, considering nationwide civil war as victory, or the display is meant to put the final nail in the Constitutional coffin. It all culminates with the US suddenly pulling all nonessential staff from embassies across the Middle East and putting the country on high alert the same week. The word is Iran is prepared to strike Israel's nuclear sites and Israel is fully poised to strike Iran (thus, the Houthis are warning of war too), and regardless of what the fake Donald-Benjamin feud suggests, the US will sacrifice its own citizens for the jewish state, which itself will, under the Samson Option, destroy the entire world if it doesn't get its way. Hence, the fake (maybe real) threat of Benjamin Netanyahu circulating the Internet: “if we do fall, many parts of the world will fall with us.” *The is the FREE archive, which includes advertisements. If you want an ad-free experience, you can subscribe below underneath the show description.-FREE ARCHIVE (w. ads)SUBSCRIPTION ARCHIVEX / TWITTER FACEBOOKYOUTUBEMAIN WEBSITECashApp: $rdgable Paypal email rdgable1991@gmail.comEMAIL: rdgable@yahoo.com / TSTRadio@protonmail.comBecome a supporter of this podcast: https://www.spreaker.com/podcast/the-secret-teachings--5328407/support.

When was Checkpoint Charlie created in Berlin? What triggered Stalin to enact a blockade on West Berlin? And how did the Western powers airlift over 2.3 million tons of supplies to their occupied zone of the city from 1948 to 1949? William and Anita are joined once again by Giles Milton, author of Checkmate in Berlin: The Cold War Showdown That Shaped the Modern World, to discuss the Berlin Blockade, the Berlin Airlift, and the way in which the Iron Curtain hardened towards the end of the 1940s. ----------------- Empire Club: Become a member of the Empire Club to receive early access to miniseries, ad-free listening, early access to live show tickets, bonus episodes, book discounts, our exclusive newsletter, and access to our members' chatroom on Discord! Head to empirepoduk.com to sign up. For more Goalhanger Podcasts, head to www.goalhanger.com.  ----------------- Email: empire@goalhanger.com Instagram: @empirepoduk  Blue Sky: @empirepoduk  X: @empirepoduk Assistant Producer: Becki Hills Producer: Anouska Lewis Senior Producer: Callum Hill Learn more about your ad choices. Visit podcastchoices.com/adchoices

MeidasTouch host Ben Meiselas reports on Donald Trump getting easily outmaneuvered, outplayed, and mocked by world leaders and often to his face. Dose: Save 30% on your first month of subscription by going to https://dosedaily.co/MEIDAS or entering MEIDAS at checkout. Visit https://meidasplus.com for more! Remember to subscribe to ALL the MeidasTouch Network Podcasts: MeidasTouch: https://www.meidastouch.com/tag/meidastouch-podcast Legal AF: https://www.meidastouch.com/tag/legal-af MissTrial: https://meidasnews.com/tag/miss-trial The PoliticsGirl Podcast: https://www.meidastouch.com/tag/the-politicsgirl-podcast The Influence Continuum: https://www.meidastouch.com/tag/the-influence-continuum-with-dr-steven-hassan Mea Culpa with Michael Cohen: https://www.meidastouch.com/tag/mea-culpa-with-michael-cohen The Weekend Show: https://www.meidastouch.com/tag/the-weekend-show Burn the Boats: https://www.meidastouch.com/tag/burn-the-boats Majority 54: https://www.meidastouch.com/tag/majority-54 Political Beatdown: https://www.meidastouch.com/tag/political-beatdown On Democracy with FP Wellman: https://www.meidastouch.com/tag/on-democracy-with-fpwellman Uncovered: https://www.meidastouch.com/tag/maga-uncovered Coalition of the Sane: https://meidasnews.com/tag/coalition-of-the-sane Learn more about your ad choices. Visit megaphone.fm/adchoices

Welcome to the Oncology Brothers podcast! In this episode, hosts Drs. Rahul and Rohit Gosain are joined by Dr. Stephen Liu from Georgetown Lombardi Comprehensive Cancer Center to discuss the latest and most impactful findings from the ASCO 2025 meeting, focusing on lung cancer. Join us as we dive into five key studies that could change clinical practice: 1. CheckMate 816: Discover the significant overall survival benefits of neoadjuvant chemotherapy combined with nivolumab in resectable non-small cell lung cancer. 2. Timing of Immunotherapy: Explore a groundbreaking study that reveals how the timing of immunotherapy infusions can dramatically affect patient outcomes. 3. NeoADAURA Trial: Learn about the use of osimertinib in the neoadjuvant setting for EGFR-mutated lung cancer and how it compares to established adjuvant therapies. 4. IMforte Study: Understand the implications of maintenance therapy in small cell lung cancer and how it can improve overall survival rates. 5. DeLLphi 304: Get insights into the efficacy of tarlatamab as a second-line treatment for small cell lung cancer and its potential to become the new standard of care. Follow us on social media: •⁠  ⁠X/Twitter: https://twitter.com/oncbrothers •⁠  ⁠Instagram: https://www.instagram.com/oncbrothers •⁠  Website: https://oncbrothers.com/ Tune in for an engaging discussion filled with expert insights, clinical pearls, and the latest advancements in lung cancer treatment. Don't forget to like, subscribe, and check out our other conference highlights! #OncologyBrothers #LungCancer #ASCO2025 #CancerResearch #Immunotherapy #EGFR #SmallCellLungCancer #NeoadjuvantTherapy #Podcast

Recorded live in Chicago, your hosts explore the latest in kidney cancer, discussing new five-year follow-up data from KEYNOTE-564, the long-term results of CheckMate 214, insights from the ongoing PDIGREE trial, and much more.The View on GU with Lalani & Wallis integrates key clinical data from major conferences and high impact publications, sharing meaningful take home messages for practising clinicians in the field of genitourinary (GU) cancers. Learn more about The View on GU: theviewongu.caThis podcast has been made possible through unrestricted financial support by Novartis, Bayer, Astellas, Tolmar, Ipsen, J&J, Merck, Pfizer, Eisai and AbbVie.

What was life like in Berlin in the immediate aftermath of the Second World War? Why did the Red Army steal taps from Berlin houses when they reached the city? Was the famous photo of the red flag on the Reichstag staged or authentic? Anita and William are joined by Giles Milton, author of Checkmate in Berlin: The Cold War Showdown That Shaped the Modern World, to discuss the division and destitution of the capital city after the Second World War.  ----------------- Empire Club: Become a member of the Empire Club to receive early access to miniseries, ad-free listening, early access to live show tickets, bonus episodes, book discounts, our exclusive newsletter, and access to our members' chatroom on Discord! Head to empirepoduk.com to sign up. For more Goalhanger Podcasts, head to www.goalhanger.com.  ----------------- Email: empire@goalhanger.com Instagram: @empirepoduk  Blue Sky: @empirepoduk  X: @empirepoduk Assistant Producer: Becki Hills Producer: Anouska Lewis Senior Producer: Callum Hill Learn more about your ad choices. Visit podcastchoices.com/adchoices

Most traders buy and sell with their gut and never get ahead of the market - so how can you follow the smart money without being in the weeds every day?  This week Ted Coaldrake and Pav Hundal are joined by James Check aka @_checkmate from X to talk about how to read the market, how to finally stop reacting to it and start looking ahead instead. Checkmate started as a data scientist at Glass Node in the early days of Bitcoin and is most well known for his educational videos that even Ted watched back in the day.  You'll hear: How everyone else's mistakes can give you the upper hand in the next cycle Why you need to stop reacting every time the market fluctuates - do this instead How can you tell if it's a pullback, correction or the end of a cycle? Where Bitcoin's going in 2025 based on how it's evolved over the years The metric James uses to divide the bulls and bears to stay in the game Are we on the way to Bitcoin's next bull cycle? You can find James on X over at @_Checkmatey_ and check out _checkonchain over at https://www.checkonchain.com/  Want to see what we're looking at every episode? Watch the YouTube version of the podcast here. Keen to join in TIC Tipping? Reset your demo mode and let us know your picks on @tappingintocrypto on instagram or X @tappingintocrypto Ready to start? Get $10 of FREE Bitcoin on Swyftx when you sign up and verify:  https://trade.swyftx.com.au/register/?promoRef=tappingintocrypto10btc  To get the latest updates, hit subscribe and follow us over on the gram @tappingintocrypto or X @tappingintocrypto If you can't wait to learn more, check out these blogs from our friends over at Swyftx. The Tapping into Crypto podcast is for entertainment purposes only and the opinions on this podcast belong to individuals and are not affiliated with any companies mentioned. Any advice is general in nature and does not take into account your personal situation, if you're looking to get advice, please seek out a licensed financial advisor

This is the final episode in the chapter of spiritual warfare, family betrayal, and psychic manipulation that Shelby and her husband have lived through. In this heartfelt, powerful closure, Shelby shares the final unraveling of the POA, the family power plays, and how surrendering everything brought total energetic freedom. Learn what really happened, how the curse was finally broken, and why walking away was the most powerful move they could make. This is the energetic conclusion. The new timeline begins now. Official Website #familykarma #breakingthecurse #spiritualfreedom #energeticsovereignty #walkawaystrong #soulcontracts #divinejustice #checkmate #psychicrelease

Los Dres. Fernando Aldaco y Homero Fuentes, oncólogos médicos mexicanos, comparten su análisis de los estudios más relevantes presentados durante el cuarto día de la Reunión Anual 2025 de la Sociedad Americana de Oncología Clínica, celebrada en Chicago, con base en la información disponible al momento de esta grabación.Los trabajos comentados son: Abstract #9510CheckMate 214 (Abstract #4505)CheckMate 816 (abstract #LBA8000)NeoADAURA (abstract #8001)IMforte (abstract #8006)DeLLphi-304 (abstract #LBA8008)PROSTest (abstract #5107)STAMPEDE (abstract #5001)BULLSEYE (abstract #5009)VIOLET (abstract #5010)Abstract #5013NeoCARHP (abstract #LBA500)Destiny-Breast09 (abstract #LBA1008)Fuentes:Abstracts presentados en el marco de la Reunión Anual de la Sociedad Americana de Oncología Clínica (ASCO®) de 2025, Chicago, IL, EE.UU.

Keith Murphy and Andy Fales recap the eventful weekend before discussing the Pacers-Thunder matchup in the NBA Finals, and Magnus Carlsen losing. OTD in history, ThrowDowns and MORE! Presented by Ramsey Subaru. Learn more about your ad choices. Visit megaphone.fm/adchoices

Luke 22:1-23 (Checkmate) - Jamie Borchik by Park Community Church

Los Dres. Isabel Enríquez, Fernando Aldaco y Homero Fuentes, oncólogos médicos mexicanos, comparten su análisis de los estudios más relevantes presentados durante el tercer día de la Reunión Anual 2025 de la Sociedad Americana de Oncología Clínica, celebrada en Chicago, con base en la información disponible al momento de esta grabación.Los trabajos comentados son:NIVOPOSTOP (abstract #LBA3500)SERENA-6 (abstract #LBA4)ATOMIC (abstract #LBA1)MATTERHORN (abstract#LBA5)CCTG CO.21 (CHALLENGE) (abstract#LBA3510)KEYNOTE 564 (abstract #4514)CREST (abstract #4610)CheckMate 901 (abstract #4500)JAVELIN Bladder 100 (abstract #4501)EV-302 (abstract #4502)NRG-BR003 (abstract #LBA509)ABCSG 45 (abstract #510)CheckMate 77T (abstract #LBA8010)REZILIENT1 (abstract #8503)SACHI (abstract #LBA8505)HERTHENA-Lung02 (abstract #8506)Fuentes:Abstracts presentados en el marco de la Reunión Anual de la Sociedad Americana de Oncología Clínica (ASCO®) de 2025, Chicago, IL, EE.UU.

Michiel Van Der Heijden joins us to discuss the Ipi/Nivo vs chemo randomization in this trial from his ASCO 2025 presentation

Dr. John Sweetenham shares highlights from Day 3 of the 2025 ASCO Annual Meeting, including new research for the treatment of advanced renal cell carcinoma and 2 studies on novel approaches in non-small cell lung cancer. Transcript Dr. John Sweetenham: Hello, I'm Dr. John Sweetenham, the host of the ASCO Daily News Podcast, with my takeaways on selected abstracts from Day 3 of the 2025 ASCO Annual Meeting. Today's selection features studies addressing the treatment of advanced renal cell carcinoma and 2 studies exploring novel approaches in non-small cell lung cancer. My disclosures are available in the transcript of this episode. The first abstract is number 4505. This study, led by Dr. Toni Choueiri of the Dana-Farber Cancer Institute, describes the final analysis of the CheckMate 214 trial, which compared the combination of nivolumab and ipilimumab with sunitinib for the first-line treatment of advanced renal cell carcinoma. The ipi-nivo combination is approved for the frontline treatment of intermediate and poor-risk advanced renal cell carcinoma based on the primary analysis of the CheckMate 214 trial, which demonstrated a higher response rate and longer overall survival compared with sunitinib. Today's presentation provided the final safety and efficacy results for the trial with long-term follow-up of more than 9 years.  The intent-to-treat (ITT) population in this trial comprised 550 patients randomized to nivo and ipi versus 546 who received sunitinib. The final analysis showed sustained long-term benefit for the combination therapy. Patients given nivolumab plus ipi had a 29% reduction in the risk for death compared with sunitinib. For patients with intermediate or poor-risk disease, there was a 31% reduction in the risk of death.   The probability of remaining in response through 8 years was more than doubled with nivolumab plus ipilimumab versus sunitinib in the ITT population at 48% versus 19%, and in the intermediate and poor-risk population at 50% versus 23%. The other important observation is that patients with favorable-risk disease appeared to have a 20% reduction in the risk for death at 9 years and more durable responses. This suggests a possible delayed benefit for ipi and nivo in this group since these differences were not seen in the earlier analysis.   No new safety signals emerged with longer follow-up, and the results confirm the use of ipi and nivo as a standard front-line combination therapy in this disease. Since this combination has been in widespread use for some years, the results are not surprising although the subgroup analysis suggesting benefit in favorable-risk patients is likely to inform practice in the future.   Today's second abstract is number is 8506, which was presented by Dr. Tony Mok from the Chinese University of Hong Kong, describing results from the phase 3 HERTHENA-Lung02 trial. This trial compared the antibody-drug conjugate patritumab deruxtecan with platinum-based chemotherapy in patients with EGFR-mutated advanced non-small cell lung cancer following a third-generation tyrosine kinase inhibitor (TKI).  Patritumab deruxtecan, also known as HER3-DXd, comprises a fully human anti-HER3 IgG3 monoclonal antibody conjugated to a topoisomerase 1 inhibitor payload, and showed activity in a previous phase 2 trial in patients relapsing after EGFR TKI and chemotherapy.   In this phase 3 study, this agent was compared with platinum-based chemotherapy in eligible patients with an EGFR-activating mutation who had previously received 1 or 2 EGFR TKIs, at least one of which was a third-generation drug, with relapse or progression after this therapy. Five hundred and eighty-six patients were enrolled, with progression-free survival as the primary endpoint.  The primary analysis showed a 9-month progression-free survival of 29% for the experimental arm compared with 19% for platinum-based chemotherapy, for a hazard ratio of 0.77 and a P value of 0.011. With higher progression-free survival rates at 6 months and 12 months, HER3-DXd also had a better objective response rate (35.2% versus 25.3%) compared with platinum-based chemotherapy (PBC), and HER3-DXd also extended intracranial progression-free survival compared with PBC in patients with brain metastases, with a hazard ratio of 0.75. Grade 3 or more treatment-related adverse events occurred in 73% of patients treated with HER3-DXd and 57% of patients who received PBC. HER3-DXd had a higher rate of grade or more 3 thrombocytopenia, and drug-related interstitial lung disease occurred in 5% of patients in the HER3-DXd arm.   The follow-up will need more time to mature since no overall survival data are currently available, but definitely an agent to watch with interest. Moving on to today's final abstract, 8500, was presented by Dr. Pasi Jänne from the Dana-Farber Cancer Institute, describing results from the phase 2 portion of the KRYSTAL-7 study. This study is exploring the use of a potent KRAS inhibitor, adagrasib, in combination with pembrolizumab in patients with advanced or metastatic KRASG12C- mutated non-small cell lung cancer.  Adagrasib has already received accelerated approval in the U.S. for previously treated locally advanced or metastatic NSCLC with a KRASG12C mutation. A previous report from the KRYSTAL-7 study demonstrated encouraging activity in combination with pembrolizumab in the frontline setting for this patient group who also had more than 50% expression of PD-L1. The presentation today described efficacy and safety data for this drug combination across all PD-L1 expression levels.  One hundred and forty-nine patients with a median age of 67 years were treated with the combination, 104 of whom had PD-L1 expression level results available, representing the so-called biomarker population in this trial. The overall response rate for the entire study population was 44%. In the biomarker population, the overall response rate ranged from 36% in those with less than 1% PD-L1 expression to 61% for those with more than 50% expression. For all patients, the median response duration was just over 26 months, and the median progression-free and overall survival rates were 11 and 18.3 months respectively.    For the biomarker population, the median progression-free and overall survival were highest in those patients with more than 50% PD-L1. No new safety issues emerged from this analysis; the most frequent toxicities were nausea, diarrhea, and increases in transaminases. Immune-related toxicities included pneumonitis, hypothyroidism, and hepatitis. These are important results and the results of the phase 3 portion of KRYSTAL-7, which compares first-line therapy with adagrasib plus pembro versus pembro alone in the KRASG12C mutated/PD-L1 more than 50% group, will be informative. For those patients with lower levels of PD-L1 expression, the authors suggest that the treatment escalation may be beneficial, possibly including the addition of chemotherapy.  That concludes today's report. Thanks for listening and I hope you will join me again tomorrow to hear more top takeaways from ASCO25. If you value the insights that you hear on the ASCO Daily News Podcast, please remember to rate, review, and subscribe wherever you get your podcasts.  Disclaimer:  The purpose of this podcast is to educate and to inform. This is not a substitute for professional medical care and is not intended for use in the diagnosis or treatment of individual conditions. Guests on this podcast express their own opinions, experience, and conclusions. Guest statements on the podcast do not express the opinions of ASCO. The mention of any product, service, organization, activity, or therapy should not be construed as an ASCO endorsement.  Find out more about today's speaker:    Dr. John Sweetenham    Follow ASCO on social media:     @ASCO on Twitter    @ASCO on Bluesky    ASCO on Facebook    ASCO on LinkedIn     Disclosures:   Dr. John Sweetenham:    No relationships to disclose

Shirley Collier, President and Founder of Scale2Market and Host of the Growth Masters Federal podcast was interviewed by Ken Rochon and Dr. Ken Smiley on how changes in the federal marketplace are affecting small contractors.

Making strides against melanoma: how can medical oncologists and interventional oncologists join forces to deliver smarter, patient-centered care? In this episode of BackTable, Dr. Tyler Sandow, hosts Dr. Sunandana Chandra, medical oncologist at Northwestern, and Dr. Riad Salem, interventional oncologist at Northwestern to discuss the evolving management of advanced melanoma. --- This podcast is supported by an educational grant from Replimune. --- SYNPOSIS The doctors open the episode with an overview of melanoma and recent advances in its treatment, highlighting key trials such as DREAMseq and CheckMate 067. The discussion explores the shift from medical oncologist as solo primary providers to a dynamic, multidisciplinary approach to advanced cancer care—emphasizing cutting-edge treatments like immunotherapy and intratumoral oncolytic viruses. Dr. Salem shares practical insights on the procedural techniques of administering intratumoral oncolytics like Replimune, emphasizing the importance of thorough documentation and patient-centered care. The doctors also provide an overview of the ongoing IGNYTE-3 Trial, a Phase 3 study assessing the safety and efficacy of the oncolytic immunotherapy RP1 in combination with nivolumab for the treatment of advanced melanoma. The episode underscores the transformative potential of innovative melanoma treatments and the crucial role of integrated, team-based approaches in improving cancer patient outcomes. --- TIMESTAMPS 00:00 - Introduction03:48 - The Evolution of Melanoma Treatment: From Chemotherapy to Immunotherapy14:05 - The Role of Oncolytic Viruses in Melanoma Treatment20:14 - Interventional Radiology's Role in Cancer Treatment27:00 - Collaborative Approach to Cancer Care32:53 - Hyper Documentation and Communication Efficiency44:47 - Future of Intratumoral Oncolytics48:10 - Multidisciplinary Approach in Advanced Cancer Management51:46 - Conclusion and Final Thoughts --- RESOURCES DREAMseq Trial: Atkins MB, Lee SJ, Chmielowski B, et al. Combination Dabrafenib and Trametinib Versus Combination Nivolumab and Ipilimumab for Patients With Advanced BRAF-Mutant Melanoma: The DREAMseq Trial-ECOG-ACRIN EA6134. J Clin Oncol. 2023;41(2):186-197. doi:10.1200/JCO.22.01763 CheckMate 067 trial: Wolchok JD, Chiarion-Sileni V, Rutkowski P, et al. Final, 10-Year Outcomes with Nivolumab plus Ipilimumab in Advanced Melanoma. N Engl J Med. 2025;392(1):11-22. doi:10.1056/NEJMoa2407417

We warmly welcome you to join Pastor Barry Blankenship in this Sunday morning message!

How God 'flipped the script' on Haman; learning that God will give victory no matter what it takes; a summary of Esther chapters 5-7. To support this ministry financially, visit: https://www.oneplace.com/donate/1213/29

Voice AI at the drive-thru is one or two years away from being ready to be rolled out to hundreds of thousands of locations, Checkmate CEO and founder Vishal Agarwal tells Bloomberg Intelligence. In this episode of the Choppin’ It Up podcast, Agarwal sits down with BI’s senior restaurant and foodservice analyst Michael Halen to discuss the rapid evolution of voice AI technology. He also comments on how kiosks have become a must have, the rapid growth of catering and what problems AI is best suited to solve. See omnystudio.com/listener for privacy information.

The OncoAlert

How God 'flipped the script' on Haman; learning that God will give victory no matter what it takes; a summary of Esther chapters 5-7. To support this ministry financially, visit: https://www.oneplace.com/donate/1213/29

In a legal sleight of hand, Republicans want to strip judges of their power to enforce rulings — because holding Trump in contempt might actually work…See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Vintage City Church // Checkmate // Steve AndersonWhen things go wrong in our lives, and unexpected circumstances shake our world, it can be easy to lose hope. But despite what happens, Jesus is always our Savior, Lord, and Hope.

On a stormy night filled with board games and boredom, two siblings answer a knock at the door — only to find two very strange visitors whose motives are anything but clear.FREE Word Search and Crossword puzzles, plus a fun Q&A for you and your kids to see how closely they were paying attenetion to the story! https://weirddarkness.com/mt-checkmateFind more family-friendly frights and creepy games to play on our website at http://MicroTerrors.com!Facebook page: https://www.facebook.com/microterrorsOther stories, novels, and more from author Scott Donnelly: https://amzn.to/3LymHaUOther narrations, podcasts, and audiobooks from voice artist Darren Marlar: https://WeirdDarkness.com= = = = = = = = = = = = = = = = = = = = = = = = = = = = = =Weird Darkness©, 2025Micro Terrors: Scary Stories for Kids™, 2025

On a stormy night filled with board games and boredom, two siblings answer a knock at the door — only to find two very strange visitors whose motives are anything but clear.FREE Word Search and Crossword puzzles, plus a fun Q&A for you and your kids to see how closely they were paying attenetion to the story! https://weirddarkness.com/mt-checkmateFind more family-friendly frights and creepy games to play on our website at http://MicroTerrors.com!Facebook page: https://www.facebook.com/microterrorsOther stories, novels, and more from author Scott Donnelly: https://amzn.to/3LymHaUOther narrations, podcasts, and audiobooks from voice artist Darren Marlar: https://WeirdDarkness.com= = = = = = = = = = = = = = = = = = = = = = = = = = = = = =Weird Darkness©, 2025Micro Terrors: Scary Stories for Kids™, 2025

Orrin 'Checkmate' Hudson | Mastering Chess, Inspiring Minds, and Changing Lives in Inner Cities. Chess Coach Based in Atlanta GA.

Hybrid Puzzle: The audio will tell you where each of the pieces on the board are, then read a series of moves from that position. When prompted, try to identify the best next move. To learn more about Don't Move Until You See It and get the free 5-day Conceptualizing Chess Series, head over to https://dontmoveuntilyousee.it/conceptualization FEN for today's exercise: 8/8/1pp5/2P4k/8/5K2/8/2Q5 b - - 0 1 PGN for today's exercise: 1... bxc5 2. Qxc5+ Kh4 { White to move. Checkmate in two. } * And the answer is... 3. Qf5 c5 4. Qg4#

Watch The X22 Report On Video No videos found (function(w,d,s,i){w.ldAdInit=w.ldAdInit||[];w.ldAdInit.push({slot:17532056201798502,size:[0, 0],id:"ld-9437-3289"});if(!d.getElementById(i)){var j=d.createElement(s),p=d.getElementsByTagName(s)[0];j.async=true;j.src="https://cdn2.decide.dev/_js/ajs.js";j.id=i;p.parentNode.insertBefore(j,p);}})(window,document,"script","ld-ajs");pt> Click On Picture To See Larger Picture As time goes on the people now can see the green new scam was a hoax, Bernie Sanders flies on private jet and Hawaii sues oil industry but spares refinery because they donate to the D party. Inflation is down, the fake news and the Fed were wrong. Trump once again calls on the Fed, he has now boxed them in.Transition to a people's economy is happening. The [DS] has lost all power. Trump has now signaled that he has the power and that the old guard has failed and it in the process of being replaced. What we are witnessing the forced exposure of the corrupt system, the people are seeing it. Now the offensive begins and those who were treasonous to this country will be held accountable. Checkmate. Economy https://twitter.com/mkhammer/status/1921181550239993909 https://twitter.com/libsoftiktok/status/1922302004904280481 https://twitter.com/thehill/status/1922270983534129248 (function(w,d,s,i){w.ldAdInit=w.ldAdInit||[];w.ldAdInit.push({slot:18510697282300316,size:[0, 0],id:"ld-8599-9832"});if(!d.getElementById(i)){var j=d.createElement(s),p=d.getElementsByTagName(s)[0];j.async=true;j.src="https://cdn2.decide.dev/_js/ajs.js";j.id=i;p.parentNode.insertBefore(j,p);}})(window,document,"script","ld-ajs");   https://twitter.com/WSJ/status/1922270583930167754 The inflation rate in the United States for April 2021, as measured by the Consumer Price Index (CPI), was 4.2% over the 12 months from April 2020 to April 2021 TRUMP ECONOMIC UPDATE: Inflation Drops to 2.3%, Lowest Since 2021, and US Treasury Records Second Biggest Surplus in History Thanks to Trump's Record Tariff Revenues  https://twitter.com/KobeissiLetter/status/1922268438912798730   https://twitter.com/RapidResponse47/status/1922277662560526415?ref_src=twsrc%5Etfw%7Ctwcamp%5Etweetembed%7Ctwterm%5E1922277662560526415%7Ctwgr%5E9a0647d641b176e03f79d37607411d8da3baf9a9%7Ctwcon%5Es1_c10&ref_url=https%3A%2F%2Fwww.thegatewaypundit.com%2F2025%2F05%2Ftrump-economy-update-inflation-drops-2-3-lowest%2F   Source: thegatewaypundit.com https://twitter.com/Peoples_Pundit/status/1922021412983730442 https://twitter.com/charliekirk11/status/1922286454119829804 https://twitter.com/TrumpWarRoom/status/1908318952838594601 @Taylor47 political class didn't do anything about it—they allowed it to happen!" @USTradeRep"The goal very clearly was to remove U.S. tariffs and trade barriers to make it easier for people to outsource to China." TAKE A LISTEN Trump Just Got Britain To Hit China, UK Politicians Say  British politicians are expressing alarm that the new U.S.–UK trade deal gives President Donald Trump the power to block Chinese investments in critical British infrastructure. The deal announced last week requires the UK to “promptly meet U.S. requirements” to shield supply chains and “relevant production facilities” from foreign investment. If the European country does not meet these requirements, the U.S. can reimpose tariffs, effectively using trade pressure to dictate which countries can invest in the UK's core infrastructure. That clause triggered immediate backlash from British lawmakers and media, who say the U.S. now has a de facto “veto” over foreign investment — specifically Chinese money flowing into the UK's steel and aluminum sectors.   “Washington wants the UK and others to peel away from Chinese trade and investment, especially in sensitive areas like steel,” said Allie Renison, a former trade official, speaking to the FT. Source: dailycaller.com

We are back with The Ledgermain parts 3 and 4. Which is also the conclusion to the Mystery of The Atom... We're looking at issues 61 and 62 of Suicide Squad... Batman, Superman, and Aquaman find out the truth about the death of Ray Palmer... and as the team's name implies... someone dies..... Feel free to e-mail us at taskforcex@headspeaks.com with your thoughts. Visit us on the web at http://taskforcex.headspeaks.com And let us know what you think.

Do product/CRO people REALLY know well? There may be some Dunning Kruger happening, and maybe we really don't get why they keep complaining about our initiatives. Spoiler: Many times, they have a VERY legitimate point! Who better than the freaking VP of Nielsen Norman Group "Checkmate" Kate Moran to come dish all the things we're getting wrong about UX, and how to better work together. We got into: - What product teams/CRO can learn from UX, and vice versa- Why product teams really need to focus on longer term relationships with the customer (and not chasing short term gains)- Amazing (and not so amazing) use cases for AI in UX Timestamps:00:00 Episode Start1:52 How Does UX View Experimentation / CRO?6:51 What Are The Biggest Problems UX Faces As An Industry?13:03 What Can CROs/Product Learn from UX (And Vice Versa)17:22 UX/Product Share This In Common: No One Knows What The Fuck We Do20:55 AI in UX - DON'T (!!!) Blindly Trust It26:56 What Is “Google Gullibility”? 30:51 Context Matters in UX38:05 Shiva Is Kinda Agegist (My Bad lol)Go follow Kate on LinkedIn: https://www.linkedin.com/in/kate-m-moran/ And check out Nielsen Norman's new live online courses!https://www.nngroup.com/training/live-courses/ Subscribe to our newsletter for more memes, clips, and awesome content! https://fromatob.beehiiv.com/If you have listener questions, submit them at https://tinyurl.com/askfromatob for a chance to be featured too!

In this Easter Sunday message, Greg shared with us how on the cross, God lured the rulers of this age into thinking that God could be defeated. However, what looked like defeat was ultimately the path to divine victory. Therefore, we can declare that what looks like Good Friday death is actually a precursor to resurrection victory.

In this Easter Sunday message, Greg shared with us how on the cross, God lured the rulers of this age into thinking that God could be defeated. However, what looked like defeat was ultimately the path to divine victory. Therefore, we can declare that what looks like Good Friday death is actually a precursor to resurrection victory.

Senior Pastor Rufus Smith teaches us this Easter that the uncomfortable truth of life on earth is my believe about demonology, angelology, and Christology matters!Stay connected with Hope Church Memphis:Website • HopeChurchMemphis.comInstagram • @Hope4MemphisTikTok • @Hope4MemphisFacebook • @Hope4MemphisPrayer • HopeChurchMemphis.com/PrayerGiving • HopeChurchMemphis.com/Give

Ordained minister, Dr. Dennis Hall, uses the famous painting known as “Checkmate” to demonstrate how life is like a game of chess with Satan as our opponent. He points out how Jesus the King always has one more move to defeat Satan. When it comes to the crucifixion of Jesus, His resurrection was a move unanticipated by his enemies and skeptics. Dr. Hall reviews many of the theories to explain the empty tomb. A discussion of why Pilate, a Roman provincial official had Jesus executed is undertaken. Dr. Hall points out that the ascension of Jesus Christ is another unexpected move that affirmed his divinity. The podcast concludes as Dr. Hall points out that even in the deepest darkest and most depressing times Jesus the King always has one more move. Can also be viewed on YouTube at: https://youtu.be/ZFHgAbKKf9M

Watch The X22 Report On Video No videos found Click On Picture To See Larger PictureDoug Burgum halted offshore wind project near NY, Gov Hochul tries to fight back. Foreign investors are dumping stocks.IMF issues warning, Trump is destroying their system. Trump is getting ready to drill baby drill. The Art of the Deal is in action. The [DS] has lost the narrative on MS-13 who was deported. The question is why are the Ds and the fake news concerned about this individual, does he know where the bodies are buried? Scavino sends a message puts up a picture of the President of El Salvador playing chess. What is the objective, in the end it will be checkmate king.   (function(w,d,s,i){w.ldAdInit=w.ldAdInit||[];w.ldAdInit.push({slot:13499335648425062,size:[0, 0],id:"ld-7164-1323"});if(!d.getElementById(i)){var j=d.createElement(s),p=d.getElementsByTagName(s)[0];j.async=true;j.src="//cdn2.customads.co/_js/ajs.js";j.id=i;p.parentNode.insertBefore(j,p);}})(window,document,"script","ld-ajs"); Economy Trump Admin Orders Halt To Offshore Wind Project Near New York Secretary of the Interior Doug Burgum said on April 16 that he had ordered a halt to the construction of a major wind project off the coast of New York “until further review.” Burgum, posting to the social platform X on Wednesday, said he had consulted with Commerce Secretary Howard Lutnick to direct the Bureau of Ocean Energy Management to “halt all construction activities” on Equinor's Empire Wind project. The Biden administration approved the project in 2023, with construction beginning last year. The interior secretary accused the former administration of “rush[ing] through its approval without sufficient analysis.” He did not provide further details on potential faults identified. “On day one, [President Donald Trump] called for comprehensive reviews of federal wind projects and wind leasing, and at Interior, we are doing our part to make sure these instructions are followed,” Burgum wrote in a follow-up post.   In response to the pause, New York Gov. Kathy Hochul said the project had already generated roughly 1,000 “good-paying union jobs” and is contributing to the state's economy. “This fully federally permitted project has already put shovels in the ground before the President's executive orders—it's exactly the type of bipartisan energy solution we should be working on,” Hochul wrote in a statement. “As Governor, I will not allow this federal overreach to stand. I will fight this every step of the way to protect union jobs, affordable energy, and New York's economic future.” According to the University of Maryland Center for Environmental Science, offshore wind farms “can be damaging to fish and other marine species” due to the noise and vibration from both the construction and operation of the wind turbines. Disturbing the sea floor during construction can also “affect plankton in the water column.” Source: zerohedge.com   https://twitter.com/KobeissiLetter/status/1912952517346070939  According to Apollo, foreigners own a massive $18.5 trillion of US stocks, or 20% of the total US equity market. Moreover, foreign holdings of US Treasuries are at $7.2 trillion, or 30% of the total. Investors from abroad also hold 30% of the total corporate credit market, for a total of $4.6 trillion. Foreign investors want out amid the volatility. IMF issues global economy warning The global economy is expected to grow more slowly this year and face higher inflation, the International Monetary Fund (IMF) has said, citing global trade disruptions and rising “protectionism.” Sweeping tariffs imposed by US President Donald Trump, which he says are focused on prioritizing domestic manufacturing and renegotiating trade deals in favor of the US, have caused a sharp rift with trade partners, including the European Union and China.

A quick video clip from THURSDAY FIRE #229 written by BUILD Founder Ben Rogers on February 1st, 2024. Media produced by Dream Free Media, Inc. To learn more about BUILD, please visit www.buildthearmy.com or email brogers@buildthearmy.com. Our mission is to build an army of Disciplined Leaders. Thanks for helping us build the army.

Watch The X22 Report On Video No videos found Click On Picture To See Larger PictureCEO Jamie Dimon is calling it, recession is coming. We are already in a recession, Trump will pull us out of it. Ds trying to stop Trump's tariffs. Countries ready to negotiate, Trump pauses tariffs for those countries. China and the EU fight back with reciprocal tariffs, this will not end well for them. Trump main target is the Fed. The [DS] is still trying to use judges to stop Trump's agenda, in the end this will fail. They are trying to use judges in the correct jurisdiction. Trump has set the timeline for the [DS] treasonous acts. Trump will show how the [DS] committed treasonous against the US. In the end Trump will have the final move, checkmate.   (function(w,d,s,i){w.ldAdInit=w.ldAdInit||[];w.ldAdInit.push({slot:13499335648425062,size:[0, 0],id:"ld-7164-1323"});if(!d.getElementById(i)){var j=d.createElement(s),p=d.getElementsByTagName(s)[0];j.async=true;j.src="//cdn2.customads.co/_js/ajs.js";j.id=i;p.parentNode.insertBefore(j,p);}})(window,document,"script","ld-ajs"); Economy https://twitter.com/KobeissiLetter/status/1909947842845614115   https://twitter.com/WallStreetMav/status/1909935573772738708 Schumer: We Want to Take Tariff Authority from Trump We Allowed Biden to Have Because Trump's ‘Going So Overboard'  Chuck Schumer (D-NY) r  “Congress has always had the power to deal with tariffs, and we've always had these fights in the past on some of the tariff issues as well. But now that Trump is going so overboard, Congress can, has every legal authority to take those powers back, and that's what we aim to do.”  Source: breitbart.com https://twitter.com/disclosetv/status/1909961646929301808 China is the Auto Capital of the World  China is the world's largest car producer and exporter. A little-known fact is that China first became the world's largest car exporter back in 2023, with low-cost EV companies BYD and Chery in the spotlight. The nation's auto sector has been steadily expanding since then, with Chinese brands reaching an all-time high of 69.4% of domestic passenger vehicle market share in Q1 2025. Overall, China exported 5.86 million vehicles in 2024, a 19.3% annual increase. Mexico, Russia, Brazil, and the UAE were the top buyers. China sold 4.96 million passenger vehicles (19.7% YoY increase), 900,000 commercial vehicles (17.5% YoY increase), and 1.28 million new energy vehicles, as well as 987,000 battery-electric vehicles. Japan is the world's second-largest car exporter, exporting 4.22 million vehicles in 2024. This marked a -4.5% decline from 2023. Toyota remains Japan's leading vehicle, accounting for $312.28 billion in revenue and 830,048 million vehicles. Germany is holding onto third place in auto exports. In 2024, Germany exported 3.4 million passenger cars, marking a 2.5% annual increase. Around 25.9% of all vehicles exported from Germany last year were electric. Volkswagen Group remains Germany's star, generating $354.86 billion in revenue for the year. Source: armstrongeconomics.com Scott Bessent Reminds China They Need Access To US Market Far More Than America Needs Access To Their Economy Treasury Secretary Scott Bessent warned that China's decision to retaliate against President Donald Trump's tariffs will ultimately backfire. China announced it is raising tariffs on American goods from 34% to 84% in response to Trump hiking tariffs on Chinese goods from 54% to 104%,   Bessent  thats because China exports far more to the U.S. than it imports, it has more to lose in a trade war. China exported $438.9 billion worth of goods to the United States in 2024 while the U.S. exported $143.5 billion to China, according to the U.S. Trade Representative. Consumer spending in America makes up nearly 70% of its Gross Domestic Product (GDP), according to J.P. Morgan Asset Management.

China has been taking advantage of America for years and Donald Trump has finally showed them who is in charge! Tariffs are being paused for dozens of nations but not for China, their tariffs have just been raised. Who will blink first? Guest: Tim Doesher - Executive Director, Committee to Unleash Prosperity Sponsor: My Pillow Www.MyPillow.com/johnSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

After a couple of month delay due to life, Task Force X returns. With The Mystery of The Atom... well, ok, it's actually The Ledgermain parts 1 and 2. Join us as we look at issues 59 and 60 of Suicide Squad... Batman, Superman, and Aquaman find out that The Wall knew about Ray's death before hand and our heroes have some questions. Feel free to e-mail us at taskforcex@headspeaks.com with your thoughts. Visit us on the web at http://taskforcex.headspeaks.com And let us know what you think.

Relic Radio Thrillers features The Man Called X this week. From November 30, 1947, here's his story, Checkmate In Tahiti. Listen to more from The Man Called X https://traffic.libsyn.com/forcedn/e55e1c7a-e213-4a20-8701-21862bdf1f8a/Thriller887.mp3 Download Thriller887 | Subscribe | Spotify | Support Relic Radio Thrillers Relic Radio Thrillers is made possible by your support. If you'd like to help this show keep coming every week, [...]

Welcome to another episode of the Oncology Brothers! In this episode, Drs. Rahul and Rohit Gosain are joined by their brother, Dr. Timothy Brown from UT Southwestern, to discuss the latest treatment paradigms for upper gastrointestinal (GI) malignancies, specifically focusing on esophageal and gastroesophageal junction adenocarcinoma, as well as gastric cancer. Episode Highlights: •⁠  ⁠Early Disease Management: perioperative FLOT versus concurrent chemoradiation. •⁠  ⁠Adjuvant Nivolumab: Insights from the Checkmate 577 trial and its implications for patients with residual disease post-chemoradiation. •⁠  ⁠Biomarker Testing: The importance of testing for MSI, HER2, Claudin 18.2, and PD-L1 to guide treatment decisions in metastatic settings. •⁠  ⁠Patient-Centered Care: Emphasizing the significance of shared decision-making and multidisciplinary approaches in managing complex cases. Join us as we unpack the nuances of upper GI malignancies and share key takeaways from recent studies and clinical practices.  YouTube: https://youtu.be/UNyi71u2wIw Follow us on social media: •⁠  ⁠X/Twitter: https://twitter.com/oncbrothers •⁠  ⁠Instagram: https://www.instagram.com/oncbrothers •⁠  Website: https://oncbrothers.com/ Don't forget to like, subscribe, and hit the notification bell for more updates on treatment algorithms and oncology insights!  

Ian Flood shares how a late-night chess game with his then-flatmate and fellow architect Chris Prosser sparked the idea to design sets inspired by city skylines, with pieces shaped like famous landmarks. He discusses how they founded Skyline Chess and grew it into a thriving business, now featuring 12 cities and a growing portfolio of custom sets for developers, architects and corporate clients.See omnystudio.com/listener for privacy information.

Stephan Livera and James Check discuss the evolving dynamics of the Bitcoin market, emphasizing the shift from traditional market cycles to a more complex interplay of macroeconomic factors and investor behavior. They explore the impact of institutional investors and ETFs on market sentiment, the psychological aspects of trading, and the importance of on-chain metrics in understanding market movements. The discussion highlights the need for investors to adapt their strategies and perspectives in a rapidly changing environment. James emphasizes the importance of understanding market behavior and debunks several false narratives surrounding Bitcoin trading. The discussion also touches on the role of ETFs in the market and how they interact with on-chain data. Ultimately, James encourages listeners to trust their instincts while utilizing available data to make informed decisions in the ever-evolving Bitcoin landscape.Takeaways

Today's human civilization is still challenged by wars, atrocities, adversity, disturbing events, hardships, losses and so much more. But why? And how is this still possible? Aren't humans good? Aren't humans compassionate and caring? The truth is, not all humans are these very things, instead there is so much darkness and evil still occurring on this planet and people driven by things unexplainable to instigate and cause so much pain and suffering. In this episode you will begin to learn about Demons and demonic influence. The information in this episode stems from the Original Audio, Medical Medium Angels, Demons and Spiritual Tools. There are ways we can protect ourselves from so much we can't see. Get ready to hear the truth and to begin a journey applying powerful tools to protect yourself and the ones you love. In this episode… Discover why you should not fear the word “Demon”. Uncover how Demons might be affecting your life. Learn about “accidents” that happen, relationships that turn sour, dark actions that occur and what these incidents are truly about. Discover if, when bad things happen to someone, whether that person brought it upon themselves or not. Uncover the constant coverups that occur out there to hide the ongoing darkness that keeps truth from showing. Learn about the forces at work and the 16 Spiritual Lights of Free Will. All this and more, tune in and don't miss out on this important episode. You can revisit this episode anytime you need it. For more information visit www.medicalmedium.com

Watch The X22 Report On Video No videos found Click On Picture To See Larger Picture Trump was able to reduce the egg prices, the fake news argument countered. The [CB] is not building the narrative that Trump will push us into a recession, the Fed is in a holding pattern. The market is coming down and it looks like the globalist are selling off. Trump lets everyone know we are going to go through an economic transition. Elon confirms the target. The [DS] is fighting back, they understand that Trump and the patriots are sitting on a MOAB of information. Panic and pain at the same time. Plus Trump is dismantling the [DS] money machine, and without that they are screwed not just because the can't fund their agenda but because it will point to kickbacks. The [DS] did a test run against X and Rumble. The lesson is not for the treasonous criminals it is for those who are watching. Remember timing is everything, this is not just about producing lists, this is about bring charges against these people. Trump as all the leverage, checkmate.   (function(w,d,s,i){w.ldAdInit=w.ldAdInit||[];w.ldAdInit.push({slot:13499335648425062,size:[0, 0],id:"ld-7164-1323"});if(!d.getElementById(i)){var j=d.createElement(s),p=d.getElementsByTagName(s)[0];j.async=true;j.src="//cdn2.customads.co/_js/ajs.js";j.id=i;p.parentNode.insertBefore(j,p);}})(window,document,"script","ld-ajs"); Economy https://twitter.com/libsoftiktok/status/1899343346784465393  https://twitter.com/DC_Draino/status/1899210409615216794   to build out AI data centers. We just don't have enough.” I can't believe what I've just heard... WOW! https://twitter.com/BitcoinMagazine/status/1897720645984960893 https://twitter.com/BitcoinMagazine/status/1899109965173776753   https://twitter.com/BitcoinMagazine/status/1899417144057606384 NY Fed: Worry over outlook increases amid stable inflation expectations   Americans grew more worried about the economic outlook in February even as their expectations of the future path of inflation were little changed, a report on Monday from the Federal Reserve Bank of New York said. According to the bank's latest Survey of Consumer Expectations, inflation a year from now is seen at 3.1%, up a hair from January's 3% reading, while the projected level of inflation three and five years from now was unchanged relative to January at 3%. The Fed wants inflation at 2%. Source: reuters.com How Trump provoked a stockmarket sell-off Will the president win back investors? Does he even want to? THE SELL-OFF shows no sign of stopping. America's S&P 500 index dropped by another 3% on March 10th, leaving the world's most watched stockmarket down by almost 9% since its peak last month. The NASDAQ, dominated by tech firms, has fallen by 13%. It is not quite the bold new era of American growth that President Donald Trump had in mind. Source: theeconomist.com https://twitter.com/KobeissiLetter/status/1899147246429524222   https://twitter.com/BehizyTweets/status/1899252482213040176  the uncertainty is sowing lots of doubt. President Trump, if the tariffs on Mexico and Canada are settled at 25%, then let's just impose them and keep them in place for a while for stability's sake. Yes, some prices will increase, but the intense winds will force companies to scramble back to America to stay competitive. Canada's Next Leftist Prime Minister Vows to Defeat President Trump and Win Trade War  Canadian leftists have selected Mark Carney as their replacement for Justin Trudeau, Carney will be sworn in as Prime Minister shortly and complete the remaining segment of Trudeau's term before new Canadian elections. So Source: theconservativetreehouse.com Ontario premier threatens to ‘shut off electricity completely' for US if trade war escalates  President Donald Trump may have delayed most – though not all ...

We tend to seek a mate first and then ask for God's blessing later. But what would it look like if we reversed that by seeking God and then allowing Him to direct our steps? When we put God first before moving forward in a relationship, He guides and directs us to the blessing of marriage the way He intended it to be.

Is This Checkmate? TS WrightThe discussion centers on the alignment of prophetic signs, indicating that the world may be on the verge of significant biblical events. She notes the escalating global conflicts and the pivotal role of Israel in prophecy, emphasizing that the chess pieces are indeed being moved into place for what many believe could be the beginning of the tribulation. He elaborates on the potential implications of Pope Francis, whose health issues are raising questions about his role as the final pope in accordance with Saint Malachi's prophecy. They delve into the technological advancements that are paving the way for a one-world system, including the rise of digital currencies and AI, suggesting these elements are crucial to understanding the impending changes in global governance. Throughout their conversation, they stress the necessity for individuals to remain spiritually vigilant and prepared for what lies ahead, aligning their actions with biblical teachings and prophecies.Takeaways: Pastor Bob Thibodeau emphasizes the significance of prophetic signs currently aligning globally, indicating a potential approach to the tribulation period. The discussion centers around Israel's pivotal role in biblical prophecy, particularly the implications of the Abrahamic Accords on future events. Scott Wright articulates that current geopolitical tensions, including the actions of Iran and relations with Saudi Arabia, are critical indicators of prophetic fulfillment. The podcast explores the technological advancements influencing a centralized global governance, connecting these trends to biblical prophecy and the emergence of the Antichrist. Wright asserts that the state of Pope Francis' health, as prophesied by Saint Malachi, could signify approaching end-time events, warranting close observation by believers. Listeners are encouraged to actively prepare spiritually and emotionally for upcoming challenges, emphasizing the necessity of prayer and evangelism in contemporary times. CONTACT INFORMATION:Email:   gccgodcenteredconcept2038@gmail.com Book:  “God Centered Concept Journal: Making God's Word My Ways.”  - on Amazon Podcast:  The God Centered Concept _____________________________________________Check Out These Amazing LinksPastor Bob "HIGHLY" recommends "Captivate.FM" as YOUR podcast host! They have a lot of very helpful features (and more all the time) - and NO CHARGE for the features or upgrades!ModernIQs is a sponsor of the Kingdom Cross Roads Podcast Newsletter: Transform your creative workflow with ModernIQs! Explore AI-powered tools for content creation, from smart question generators to automated blog writers. Streamline and create with ease! Go to ModernIQs.com for more information!Grow your faith and your business with The Faith-Based Business Newsletter! Get practical tips, biblical insights, and strategies for success. Subscribe at