Podcasts about Early Stage

Is AI about to replace your stock broker? Christine Healey, a pre-IPO investment expert, explains why Claude AI missed a critical detail in a deal that could have cost her client millions—and why human brokers are still essential in the private market. In this interview, Christine and Sean discuss the "wild west" of pre-IPO investing, how to avoid scams when buying shares of companies like SpaceX and Stripe, and the secret tax strategies (like the Peter Thiel Roth IRA hack) that can save you millions. They also debate whether employees selling shares before an IPO is a red flag or just smart financial planning. Check out the company: https://healeypreipo.com

Sara and Laura are obsessed with today's sweetie pie song, “Honey,” from The Life Of A Showgirl. After sharing some maternity leave updates for the podcast (and Sara's new obsession with Wuthering Heights!), the gals get into a short, sweet, and straightforward analysis of the song. Could this be the most Lover-coded song in Taylor's recent discography? This uncomplicated, confident track has the girls giggling and kicking their feet… especially knowing that Taylor's renewed sense of understanding love is so clear! Chapters(00:00) Introduction (04:02) What's On Our Plates(15:24) Taylor Updates(18:57) Analysis of 'Honey' from Life of a Showgirl(22:18) Our Personal Associations With The Song(23:42) Folk"lore" of the Song(29:15) Intro: Right To The Point, Interesting Structure Of the Song(31:09) Chorus 1: Using Kind Words For Unkind Reasons, Snarls, Bathroom Trauma (36:19) Post-Chorus 1: "Blues" Given New Meaning(39:50) Verse 1: Seasonal Dreaminess, Early Stages of A Relationship, A Question...? Reference(46:13) Verse 2: Naughty References, Wanting To See Him Everywhere, Public Relationship(49:34) Bridge: A Callback To Past Exes, "Lovely" As Passive Aggressive(53:45) Chorus 3: Fun Backing Vocals(54:47) Music Theory Analysis: Odd Structure Of The Song Symbolizes Confidence, Fun Instrumentation(57:58) Favorite Lyrics & Ratings(01:03:11) This Song As A Recipe(01:05:37) Signing Off!SUPPORT US ON PATREON! Show us some love and get monthly bonus episodes and first dibs on upcoming episode ideas. We'd be enchanted to have you join our Swiftie community!Links ReferencedBee's Knees Cocktail RecipePlease make sure to subscribe and leave a review. If you'd like to reach out to send in a question or comment, please do so via any of these platforms:email blankplatepod@gmail.comleave a voicemail at (717) 382-831Patreon (get bonus episodes and first dibs on episode ideas)YouTubeInstagramTikTokYou can also follow Sara and Laura individually:• Laura: Instagram and Tiktok• Sara: InstagramListen to our previous podcast: Passports & Pizza

Amardeep Parmar from Bae HQ welcomes Yumi Tsoy, Senior Partner & Head of Operations at Bethnal Green Ventures.Amardeep Parmar:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.linkedin.com/in/amardeepsparmar⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Yumi Tsoy: https://www.linkedin.com/in/yumi-tsoy/Bethnal Green Ventures: https://www.linkedin.com/company/bethnal-green-ventures/

n light of the alarming reports linking Trump's administration to the tragic deaths of schoolgirls in Iran, alongside Netanyahu's regime allegedly creating acid rain over Tehran and deploying chemical weapons in Lebanon, it's imperative that we confront the escalating crisis head-on. Meanwhile, as Putin intensifies his attacks on Ukraine, the drastic rise in oil prices poses a significant threat to global stability. Prime Minister Mark Carney's urgent call to Trump to discuss the economic ramifications underscores the gravity of our situation. This is not just a regional issue; the potential for conflict in the Middle East to spiral out of control and engulf the entire world is a pressing reality we cannot ignore.Join Joni Askola, who brings invaluable insights from Finland and experience as a volunteer supporting the Ukrainian war effort, as he discusses these critical matters with Laura Babcock. Their thoughtful examination of the risks we face is essential viewing. We must engage in this discussion to understand the potential consequences of inaction and to advocate for a peaceful resolution before it's too late. Don't miss this opportunity to grasp the full scope of the situation and to be part of the conversation to save democracy. Comment, Subscribe, and please share! We are in this together!#iran #canadanews #canada #canadastrong #carney #Finland #lebanon #isreal #netanyahu #usa #usapolitics #alberta #oilprices #democracy #iranwar #ww3 #ww3warning #ww3alert #ukraineAn independent podcast, the best way to support our work is by subscribing. Let's build our pro democracy community! Hosted on Acast. See acast.com/privacy for more information.

If you have ever looked "fine" on the outside while feeling fried, foggy, or oddly disconnected from the business you used to love, this episode is for you. Early-stage burnout rarely announces itself. It shows up as low-grade anxiety, constant firefighting, and a calendar packed with things that do not actually move you toward your Vision. In this conversation, Erin and Steve name the real root of early-stage burnout: it is often not the number of things you are doing. It is the number of non–Vision-aligned things you are doing.  You will discover: Why burnout can start before you look "overwhelmed" on paper. How the Goal Swamp keeps you productive without feeling fulfilled. What "Static" is, and how to treat it like wisdom instead of a problem to eliminate. Why the first signs of burnout are often spotted by the people closest to you. The leadership skill nobody teaches: protecting your time and energy like it is sacred. You do not need to wait for a breakdown to change your week. You can spot early-stage burnout sooner, name what is actually happening, and make decisions that protect your life and your business.   Resources mentioned: Your Best Week For more support on stopping early stage burnout in your life, get Your Best Week, a five-day on-demand class designed for busy leaders and business owners who want their work to be supported by their life, not the other way around. If you have been telling yourself, "I just need to push through," this is your interruption. Your Vision is allowed to lead again.

Drs. Isaacs and Traina discuss new data in HER2+ breast cancer from the 2025 San Antonio Breast Cancer Symposium, focusing on early-stage studies including DESTINY-Breast11 and DESTINY-Breast05 and how data from these studies could potentially impact patient care in the future.

In this podcast, experts Mara Antonoff, MD, FACS; Laura Alder, MD; and Stephanie Worrell, MD, FACS, discuss the latest advances in immunotherapy and EGFR-targeted treatments for patients with resectable, early-stage, non–small cell lung cancer.

A warming patter will begin to form later this afternoon, continuing through much of the week. National Weather Service meteorologist Jon Hitchcock has the forecast.

Tea Time with Talent Acquisition is proudly sponsored by Peritus Partners - ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Peritus Partners - Next Generation Recruitment⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠------------------------------What does it really take to build a talent function from scratch inside an early-stage startup?In the final episode for this season of Tea Time with Talent Acquisition, Zvjezdana Topalović, Head of Talent, unpacks the reality of hiring in high-growth, chaotic environments where there's no structure, no employer brand, and no clear roadmap. Just ambition, pressure, and the need to get it right.We cover:

Vice President JD Vance told a crowd in central Wisconsin to re-elect Republican Derrick Van Orden. The state's 3rd Congressional District is a top target for Democrats. Wisconsin voters tell a pollster they're unlikely to support new school referendums.  And, Wisconsin Assembly Speaker Robin Vos says negotiations with the governor on a tax deal are still in the early stages. But he's optimistic.

Avoid Giving Up Too Much Equity in the Early Stages Hello, this is Hall T. Martin with the Startup Funding Espresso -- your daily shot of startup funding and investing. In the early stages of a company, fundraisers should focus on the minimum amount, not the maximum. The valuation is low, and so the founders encounter greater dilution. The majority of the fundraise should be done later when the valuation has increased. Each round will cost the founder 25% of their equity. Most use convertible notes. Beware of using the convertible note as a credit card in which the founder keeps raising funds on it. At the Series A level, venture capital will check to see if there's enough equity left for their investment. The VC will also want to see enough equity left in the round for the founders. If the founders have given up too much equity in the early stages, then investors will not fund the startup. Founders should keep track of the equity they are giving up with convertible notes. They should have at least 60% of the equity by the time they approach a Series A investor. Consider these points in negotiating early-stage rounds of funding. Thank you for joining us for the Startup Funding Espresso where we help startups and investors connect for funding. Let's go startup something today. _________________________________________________________ For more episodes from Investor Connect, please visit the site at: http://investorconnect.org Check out our other podcasts here: https://investorconnect.org/ For Investors check out: https://tencapital.group/investor-landing/ For Startups check out: https://tencapital.group/company-landing/ For eGuides check out: https://tencapital.group/education/ For upcoming Events, check out https://tencapital.group/events/ For Feedback please contact info@tencapital.group Please follow, share, and leave a review. Music courtesy of Bensound.

This episode felt especially important to bring back.If you've ever found yourself emotionally attached too quickly, overlooking red flags, or confusing chemistry with compatibility, this conversation is for you.Inside this episode, I walk you through how to:Slow down without losing momentumStay emotionally grounded in the early stagesDate with intention instead of urgencyBuild real safety and discernment from the startIf dating has felt rushed, confusing, or emotionally draining lately, this is a powerful re-listen (or first listen).Ready to stop running from your emotions, rewire your attachment patterns, and embody secure attachment so you can have the kind of relationship where you are seen, heard, and loved, even on your worst days,I invite you to apply for my Private 1:1 Coaching container, Empowered Secure Love.Apply here:

Nvidia is working with investors, nonprofits, and venture firms to build earlier ties with India's fast-growing AI founder ecosystem. Also, General Catalyst's pledge marks a sharp jump from the company's earlier $500 million–$1 billion India earmark. Learn more about your ad choices. Visit podcastchoices.com/adchoices

As global supply chains fracture, AI reshapes productivity, and technology becomes a core instrument of national power, India is making an ambitious push to redefine its role in the world economy from IT services provider to deep tech superpower.In the season 2 premiere of  TechSurge, host Sriram Viswanathan brings together three defining perspectives to examine how India is positioned to become a global leader in frontier technologies, and what must go right for that vision to succeed.The episode begins with S. Krishnan, Secretary at India's Ministry of Electronics and Information Technology, who outlines how India is treating deep tech as national infrastructure. From the India Semiconductor Mission and AI compute investments to the new RDI (Research, Development & Innovation) framework, Krishnan explains how long-horizon industrial policy is being used to derisk private capital, strengthen domestic design and manufacturing, and accelerate commercialization.Next, former G20 Sherpa Amitabh Kant places India's technology ambitions in a global context. As post-WWII institutions weaken and supply chains are redrawn, Amitabh argues that India's decade of structural reforms, digital public infrastructure, and global partnerships has created a historic opening, if India can sustain free enterprise, execution discipline, and state-level reform.Finally, T.K. Kurien, CEO and Managing Partner of Premji Inves, brings the investor and operator lens. Kurien explores why India has excelled at services and business-model innovation but lagged in core technology creation and what it will take to build globally dominant deep tech companies. From patient capital and university-led innovation to focused national bets in AI applications, biotech, and semiconductors, he outlines the path from ambition to execution.Across policy, geopolitics, and capital, one message is clear: India's deep tech future will not be decided by vision alone but by alignment between government direction, private risk-taking, and long-term discipline.If you enjoy this episode, please subscribe and leave us a review on your favorite podcast platform.Sign up for our newsletter at techsurgepodcast.com for updates on upcoming TechSurge Live Summits and future Season 2 episodes.Episode LinksIndia Semiconductor Mission (MeitY): https://www.meity.gov.in/India AI Mission & AI Kosh: https://indiaai.gov.in/National Research Foundation & RDI Scheme: https://anrf.gov.in/Premji Invest: https://www.premjiinvest.com/Timestamps00:00 India's Deep Tech Inflection Point02:05 Industrial Policy as National Infrastructure06:52 Why Government Must Catalyze Product Innovation Beyond IT Services09:13 Building the Ecosystem: Talent, Research, Diaspora Return & Startup Scale13:10 India Semiconductor Mission (ISM): What's Different This Time24:56 ISM 2.0 Plans: Fixing Design Incentives & Unlocking Risk Capital27:15 IndiaAI Mission Explained: Compute, Data (AI Kosh) & Model Development33:09 Global Order Shifts: Supply Chains, Tech Power & Introducing Amitabh Kant41:19 Alliances That Matter: China, Europe/Japan Partnerships & Why the US Is Key54:11 How Government Can Take Risk: Fund-of-Funds, R&D Incentives, and Grand Challenges57:07 Dismantle Red Tape, Build World-Class Infrastructure, 01:00:57 Why Premji Invest Focused on Growth Stage (and What Changed for Early Stage)01:03:16 India vs US Investing: Where Returns Come From and Avoiding Valuation Hype01:05:28 Building India's Startup Ecosystem: Capital, Patience, and Core Tech vs Business Models01:13:41 Three Sectors to Bet On: AI Software/Agents, Biotech Breakthroughs, and Pragmatic Semiconductors

In this episode, Peg Crowley-Nowick speaks with Joseph Elassal, MD, MBA, Chief Medical Officer of Ankyra Therapeutics, about the strategic, operational, and financial realities of leading clinical development from pre-IND through proof of concept and toward commercialization.   Drawing on experience across large pharma, biotech partnerships, and early-phase oncology, Joe shares a practical roadmap for new and aspiring CMOs. They discuss how to prioritize essential capabilities, including clinical operations, regulatory strategy, biostatistics, and pharmacovigilance, while determining the right time to introduce Medical Affairs. The conversation outlines how to scale teams at critical inflection points such as IND clearance, Phase 2 proof of concept, and advancement into Phase 3.   The episode also examines investor and board expectations, CRO selection, capital efficiency, cash runway management, and the performance metrics CMOs are ultimately judged on—from disciplined milestone execution to generating meaningful clinical data. This episode offers actionable insight for biotech founders, clinical development leaders, medical affairs professionals, and emerging CMOs navigating the path from early development to launch.

As part of IASLC's ongoing series of Lung Cancer Considered podcasts in world languages, Dr. Molly Li moderates a discussion in Cantonese with two expert cardiothoracic surgeons, Dr. Ben Li, Professor from The First Affiliated Hospital of Guangzhou Medical University and, and Dr. Calvin Ng, Professor from the Chinese University of Hong Kong. The discussion: reviews surgical management of early-stage NSCLC, including VATS, and lobar versus sublobar resection; and explores novel technologies including endobronchial therapy and tubeless anesthesia. Host: Molly Li, MD Clinical Assistant Professor Department of Clinical Oncology, CUHK, Hong Kong Guests: Shuben Li, MD, PhD Professor, Department of Thoracic Surgery National Center for Respiratory Medicine The First Affiliated Hospital of Guangzhou Medical University Calvin S.H. Ng, BSc MBBS, MD Environmental Foundation Professor of Thoracic Surgery Department of Surgery The Chinese University of Hong Kong (CUHK)

In deze aflevering spreekt Patrick Polak openhartig over zijn bijna 30 jaar ervaring in het vak van venture capital. Van het overleven met zijn eigen softwarebedrijf in San Francisco tot het opbouwen van Newion: Patrick deelt zijn scherpste inzichten over wat een ondernemer succesvol maakt en waarom de wereld van Venture Capital fundamenteel is veranderd. Wat je gaat ontdekken: - De 3 Archetypes van de Founder: Patrick verdeelt ondernemers in drie 'buckets': de vrijheidszoeker die autonomie wil , de productvisionair die kickt op innovatie , en de marktvisionair die moet transformeren naar een strategisch CEO. - Het Einde van Early Stage Investing: Waarom Patrick niet meer gelooft in het huidige model. Hij legt uit hoe kapitaal een 'commodity' is geworden en waarom we in een tijdperk van "casino-investing" leven. - De Kracht van de Onderbuik: Waarom hij na tien seconden al weet of een pitch kans maakt en waarom ratio vaak wordt gebruikt om een intuïtief besluit achteraf te rechtvaardigen. - Persoonlijk Verlies en Afscheid: Een kwetsbaar gesprek over het onverwachte overlijden van zijn zakenpartner Erik, de lessen die hij daaruit trok over samenwerken en zijn naderende vertrek bij Newion. "Ik ben geen unicorn hunter. Ik wil ondernemers helpen van A naar B naar C. Als ik kan bijdragen aan één procent van jouw succes, dan ben ik een blij mens." Newion: https://newion.com/ We Love SaaS: https://welovesaas.io/ SaaS Summit Benelux: https://saassummit.io/

In this episode of the HVAC Know It All Business Edition Podcast, co-hosts Gary McCreadie and Furman Haynes of WorkHero talk with Robyn Hass, Founder and Fractional CFO of Mainstreet MEP™ by HVAC Office Solutions and Trade Finance in Ten Podcast, and Fractional MEP CFO/CHRO, FP&A and Change Management Consultant of Robyn Hass Consulting. Robyn shares her journey of building Core Mechanical, a company that successfully scaled and was eventually sold to private equity. She discusses the importance of focus in business, financial systems, and the strategies behind scaling operations, particularly for those starting small in the HVAC industry. She offers invaluable insights on niche selection, managing overhead, and the systems and tools that were crucial for her company's success. Robyn also talks about how to support solo business owners and the challenges they face in managing their businesses effectively.    Expect to Learn: - Why focus is key when scaling your business and how choosing a niche helped Robyn's company grow. - The importance of financial systems and why investing in software like QuickBooks and field management tools early on can save you headaches later. - How to manage cash flow effectively and the overhead challenges that come with scaling. - Why it's crucial to train your technicians properly and capture all job data from day one. - Robyn's advice for solo entrepreneurs, why you don't always have to grow to be successful and how to partner with others. - The best ways to ensure financial health and how understanding your net margin is more important than EBITDA. - Robyn's new offerings for business owners, including resources, boot camps, and reporting tools to help scale more efficiently.   Timestamps: [00:00] - Introduction [02:05] - Starting Core Mechanical [04:04] - Importance of Focus in the Early Stages [05:20] - The Risk of Spreading Thin [07:29] - Challenges for Small Business Owners Doing Everything [08:29] - Setting Up Systems in the Early Days [10:08] - The Need for Proper Accounting and Software [12:50] - When to Hire and the Cash Flow Challenge [13:18] - Managing Cash Flow [14:23] - The Owner's Role in Scaling [15:51] - True Profit Margins and EBITDA [17:23] - The Difference Between EBITDA and Net Profit [19:24] - Setting Owner Salaries and Business Growth [21:20] - Thoughts on Cash Payments   Follow Robyn Hass: LinkedIn: https://www.linkedin.com/in/jrobynh/ Company LinkedIn: https://www.linkedin.com/company/mainstreet-mep Company Website: https://myhvacoffice.com/   Follow Gary McCreadie: LinkedIn: https://www.linkedin.com/in/gary-mccreadie-38217a77/ Website: https://www.hvacknowitall.com Facebook: https://www.facebook.com/people/HVAC-Know-It-All-2/61569643061429/   Follow Furman Haynes on: LinkedIn: https://www.linkedin.com/in/Furmanhaynes/ WorkHero: https://www.linkedin.com/company/workherohvac/ Instagram: https://www.instagram.com/hvacknowitall1/  

In this episode of the Oncology Brothers podcast, hosts Rahul and Rohit Gosain dived deep into the evolving landscape of breast cancer treatment algorithms, focusing on early and locally advanced hormone receptor-positive breast cancer. Joined by Dr. Erica Mayer, a breast medical oncologist at the Dana-Farber Cancer Institute.  Listen us on: Spotify: https://open.spotify.com/show/31BXhY9FM4gPWG10WgE11o Follow us on social media: •⁠  YouTube: https://www.youtube.com/@oncologybrothers/ •⁠  ⁠X/Twitter: https://twitter.com/oncbrothers •⁠  ⁠Instagram: https://www.instagram.com/oncbrothers •⁠  Website: https://oncbrothers.com/ The discussion covered: • The role of chemotherapy in early-stage hormone receptor-positive breast cancer, including the use of anthracyclines versus taxane-based approaches. • Insights from the TAILORx trial and the implications of Oncotype DX scores in treatment decisions. • The ongoing OFSET trial and its potential impact on premenopausal patients with low recurrence scores. • The use of CDK4/6 inhibitors, including ribociclib and abemaciclib, in the adjuvant setting, along with their side effect profiles and dosing considerations. • The significance of the recent lidERA trial results featuring giredestrant and its implications for future treatment strategies. Join us as we explore the latest data, treatment paradigms, and the importance of patient-shared decision-making in breast cancer care. Don't forget to subscribe for more insights and staying up to date in the field of cancer.  #EarlyBreastCancer, #OncotypeDX, #CDK46inhibitors, #OralSERD, #AdjuvantTherapy, #OncologyBrothers

Amardeep Parmar from Bae HQ welcomes Akash Bajwa, Principal at Earlybird.Amardeep Parmar:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.linkedin.com/in/amardeepsparmar⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Akash Bajwa: https://www.linkedin.com/in/akashbajwa/Earlybird: https://earlybird.com/

Manuel Grossmann (Amino Collective) spricht über Positionierung im Venture Capital — und warum echte Partnerschaft für Gründer mehr ist als ein Versprechen auf der Website. Du erfährst, weshalb viele Investoren zwar „Early Stage“ sagen, aber spät investieren, wie sich Amino Collective bewusst davon abgrenzt und warum thematische Spezialisierung ein entscheidender Vorteil für Gründer ist. Was du lernst: Warum viele Fonds frühe Investments versprechen, sie aber selten umsetzen. Wie sich spezialisierte Fonds positionieren, um frühere und bessere Entscheidungen zu treffen. Weshalb Flexibilität bei Ownership, Ticketgröße und Rolle entscheidend ist. Wie Gründer Investoren besser einschätzen können, bevor sie Gespräche führen. Warum Venture Capital eine gesellschaftliche Funktion hat – und nicht nur Rendite liefern sollte. l ALLES ZU UNICORN BAKERY: https://stan.store/fabiantausch   Mehr zu Manuel: LinkedIn: ⁠https://de.linkedin.com/in/manuel-grossmann⁠  Website: ⁠https://www.aminocollective.com/⁠  Join our Founder Tactics Newsletter: 2x die Woche bekommst du die Taktiken der besten Gründer der Welt direkt ins Postfach: https://www.tactics.unicornbakery.de/

In this episode of Innovation Meets Leadership, host Natalie Born sits down with Braydan Young, B2B tech entrepreneur, co-founder of Sendoso, and founder of Slash Experts, to unpack what innovation really looks like inside early-stage startups.Braydan shares hard-earned lessons from building and scaling multiple companies—covering everything from replacing traditional sales demos with peer-to-peer trust, to navigating rapid product cycles, delegation, feedback culture, and decision-making under uncertainty. [00:00 – 01:22] Welcome & Braydan's Founder JourneyIntroducing Braydan Young and his background in B2B tech startupsFrom Sendoso to Slash Experts: why early-stage building still excites him[01:23 – 03:08] The Idea Behind Slash ExpertsHow customer “back-channeling” inspired a new go-to-market modelTurning real customers into trusted sales advocates[03:09 – 04:31] The Educated Buyer & Faster Sales CyclesWhy buyers now complete most of the sales journey before a demoHow trust accelerates deals and reduces friction[04:32 – 06:09] Scaling Principles: Delegation & FocusWhy founders can't (and shouldn't) do everything themselvesTrusting your team without micromanaging[06:10 – 07:48] Tools, Chaos, and Personal ProductivityClickUp, handwritten to-do lists, and managing multiple workflowsWhy speed matters more than perfection[07:49 – 09:55] Staying Innovative as a Small, Scrappy TeamWhy small teams outperform large ones at innovationRadical transparency: sharing board decks, finances, and goalsTreating employees like owners from day one[09:56 – 12:22] Rapid Product Development & Weekly ReleasesHow product cycles have shifted from quarterly to weekly releasesThe impact on sales enablement, marketing, and customer experienceWhy staying aligned internally is harder—but more critical—than ever[12:23 – 14:47] Curiosity, AI, and Learning at SpeedUsing AI tools to synthesize information fasterBuilding curiosity into hiring and company cultureWhy innovation requires awareness beyond your immediate market[14:48 – 17:26] Innovation, Risk, and Hypothesis-Driven LeadershipTreating decisions as hypotheses—not fixed truthsAsking the uncomfortable question: “Where are we failing?”Why early customers are your greatest innovation partners[17:27 – 20:52] Feedback, Failure, and Healthy CulturesWhy most organizations avoid real feedbackTurning failure into actionable learningCreating a culture of candor without ego defensiveness[20:53 – 22:45] Balancing Innovation with Day-to-Day ExecutionSprinting between customer work, prospecting, and internal systemsStructuring focus as teams grow toward 50+ peopleKnowing when your operating model must change[22:46 – 24:51] Growth Inflection Points & Company ValuesLessons from hypergrowth at SendosoWhy values must be defined before rapid hiringHelping people self-select into (or out of) your culture[24:52 – 26:34] Final Takeaways & Where to ConnectLeadership lessons from multiple startup cyclesBalancing ambition, family, and sustainable performanceWhere to find Braydan and learn more about Slash Experts“Product-market fit isn't a milestone—it's a question you should be asking on every call.” – Braydan Young“Your first customers stick with you because they believe in the idea, even when you're still breaking things.” – Braydan Young“If you're not asking where you're failing, you're probably missing your biggest opportunity.” – Braydan YoungLinkedIn: Braydan Young – linkedin.com/in/braydanyoung/Website: slashexperts.com

What if your money could do more than sit in a retirement account?This month on Smart Women Talk, we're joined by Marcia Dawood, global leader in angel investing and author of Doing Good While Doing Well, for a conversation that will completely change how you think about investing.Marcia breaks down what angel investing actually is (no finance degree required), why women are uniquely wired to be exceptional investors, and how anyone—yes, even with as little as $100—can invest in ideas, founders, and innovations they care about.You'll learn:What angel investing really means (and how it's different from Shark Tank)Why women founders receive only ~2% of venture capital—and how that can changeHow to start investing with your values, not just your walletCreative ways to invest using donor-advised funds, IRAs, and equity crowdfundingSimple, low-risk first steps to explore this world without feeling overwhelmedIf you've ever wanted your money to reflect what matters most to you, this episode is a must-listen.Marcia Dawood is an early-stage investor and national leader in expanding women's access to capital, now championing a bold new message with her forthcoming book, Unapologetic Wealth: Rewrite Your Money Story from Any Beginning  (March 10, 2026).As Chair of the SEC's Small Business Capital Formation Advisory Committee, a venture partner with Mindshift Capital, and chair emeritus of the Angel Capital Association, she has helped rewrite the rules of who gets to build and benefit from innovation.She founded the ACA's Growing Women's Capital Group and has invested in more than 50 early-stage companies and funds, always pushing for diversity, impact, and financial agency. Marcia is also the award-winning author of Do Good While Doing Well and a TEDx speaker whose work inspires women to step into wealth with confidence and zero apology.Connect with Marcia at MarciaDawood.com.DISCLAIMER: The information Smart Women's Empowerment and Smart Women Talk provides is for general informational purposes only. All information is provided in good faith; however, we make no representation or warranty of any kind, express or implied, regarding the accuracy, adequacy, validity, reliability, availability, or completeness of any information. UNDER NO CIRCUMSTANCE SHALL WE HAVE ANY LIABILITY TO YOU FOR ANY LOSS OR DAMAGE OF ANY KIND INCURRED AS A RESULT OF THE USE OF OR RELIANCE ON ANY INFORMATION PROVIDED SOLELY AT YOUR OWN RISK. We cannot and do not offer financial and/or medical advice. The information is provided for general informational and educational purposes only and is not a substitute for professional advice. Accordingly, we encourage you to consult with the appropriate professionals before taking any actions based on such information.

The Software Startup Specialist Blueprint Helping Founders Go From Idea to InvestmentIn this week's episode, Sacha sits down with Stuart Prestedge, entrepreneur and tech startup founder with nearly 40 years in the game, to unpack what it really takes to build a startup that survives, gets funded, and scales with confidence.Stuart has lived both sides of the founder journey. He has experienced the highs of three exits and the lows of failure. Through it all, he discovered what he is most passionate about now: helping founders succeed from napkin scratch to launch and beyond.Broadcasting globally from Prague to Miami, this conversation goes deep on the fundamentals that never change, the mindset that keeps founders moving, and the systems that turn early stage chaos into investor ready clarity.We dig into:The hardest lesson from failure and why it is a natural part of innovationTenacity as the real indicator of success and how to keep going through setbacksThe exit that taught him the most and why flexibility and future proofing matterWhy founders think they need funding but actually need foundationsThe difference between pitch deck work and building a real investment ready businessThe three founder stages he supports from idea stage, pitch ready, and post launch community supportFounder credibility and why investors invest in people as much as productsSprint sessions for time poor founders and what they learn from the right questionsPreparing for scale before launch and why de risking is a CEO's jobWhy co founders and community can be the difference between burnout and momentumHow Stuart actually markets himself today with simple video ads that build trustOne word, one habit, one myth including why you should validate before you buildKey Takeaways:Failure is feedback, not a verdictStrong foundations create confidence for founders and trust for investorsFlexibility future proofs products without slowing down executionFounder story and mission reduce risk and increase investor beliefCommunity keeps founders accountable, sane, and moving forwardSell and validate before you build the MVP Connect with Stuart:LinkedIn: Stuart PrestedgeSoftware Startup SpecialistFollow Us:

Republicans unveil the most extreme federal voting restrictions proposed in modern history, Tennessee officials are accused of quietly propping up a payday lender's failed sports betting operation, and scholars warn the U.S. may be entering the early stages of genocide against trans Americans.NewsNew GOP anti-voting bill may be the most dangerous attack on voting rights ever How a Tennessee Official Kept Advance Financial's Sports Betting Company AliveExperts Warn U.S. in Early Stages of Genocide Against Trans Americans Follow @PodSaveThePeople on Instagram.

This Week In Startups is made possible by:Quadratic - http://quadratic.ai/twistToday's show: Don't get distracted! Here are the MOST CRUCIAL aspects of running a startup, where founders need to keep their full and uninterrupted focus.- Make sure you're saving up your cash- Why you need to just get started and build SOMETHING- Trust and reliability is EVERYTHING for new products- Why distribution should be your top priorityDownload all this practical and tactical startup advice from seasoned veterans Jason Calacanis, Amanda Bradford, and William P. Barnes in this Tokyo edition of TWiST.Timestamps:(00:00) Amanda and Will's big takeaways from Founder U in Saudi Arabia and now Tokyo(3:19) Why cash flow management is so important before you find PMF(5:57) Why first-time founders get the order of operations wrong(6:45) Just build SOMETHING, even if it's taped together(11:19) “Focus is everything in the early stages”(14:17) From a wedge to a bridge(15:50) Quadratic - Bringing the productivity boost of AI into your spreadsheets. Visit http://quadratic.ai/twist to sign up and use the code TWIST to get one free month of their pro tier subscription.(18:45) What to put on your “Not Right Now” list(19:11) Embracing simplicity(22:00) The importance of trust and reliability (especially for Uber!)(28:12) Why innovation needs a constraining variable(33:40) To really drive word of mouth, you have to overdeliver(36:32) Distribution is the primary job of a founder/CEO(38:19) Some of the panel's favorite distribution hacks(45:54) Why Jason respects Japan's commitment to excellence and competency(49:38) Looking for “high slope” in early employees(53:11) Transitioning your team from early-stage startup to growth(57:45) Whoever writes it down gets credit for the idea(58:04) Q: Has the meaning of money changed for the panel now that they've had successful exits?*Subscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.com/Check out the TWIST500: https://twist500.comSubscribe to This Week in Startups on Apple: https://rb.gy/v19fcp*Follow Lon:X: https://x.com/lons*Follow Alex:X: https://x.com/alexLinkedIn: https://www.linkedin.com/in/alexwilhelm/*Follow Jason:X: https://twitter.com/JasonLinkedIn: https://www.linkedin.com/in/jasoncalacanis/*Thank you to our partners:(15:50) Quadratic - Bringing the productivity boost of AI into your spreadsheets. Visit http://quadratic.ai/twist to sign up and use the code TWIST to get one free month of their pro tier subscription.Check out all our partner offers: https://partners.launch.co/

One of the greatest challenges facing any start-up is “crossing the chasm”: bridging the gap between early adopters and mass-market buyers. Yet many promising businesses struggle even to reach the chasm. Often, founders leap in with money and a dream, only to hit a wall. How can start-up founders diagnose and fix problems in order to arrive at this critical point? In Reaching the Chasm: How to Drive Your Early-Stage Start-Up to Scale (Columbia Business School Publishing, 2025), Edward G. Amoroso provides an indispensable guide for start-ups looking to get off the ground and scale up to the next level. Getting to the chasm, as he illustrates through dozens of real-world case studies, requires long-term vision. Founders must focus on their core belief system―not simply what they do but why they are in business in the first place. Buyers connect with start-ups based on shared beliefs, and any founding team that does not understand this secret will struggle to build relationships with customers. Amoroso shares field-tested guidance for businesses in different spaces and stages on crafting a compelling message, understanding customers, benchmarking against competitors, and leveraging what makes a company irreplaceable. For founders, venture capital teams, private equity firms, investors, and readers with an interest in entrepreneurship, Reaching the Chasm is the road map for early-stage start-up success. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/new-books-network

One of the greatest challenges facing any start-up is “crossing the chasm”: bridging the gap between early adopters and mass-market buyers. Yet many promising businesses struggle even to reach the chasm. Often, founders leap in with money and a dream, only to hit a wall. How can start-up founders diagnose and fix problems in order to arrive at this critical point? In Reaching the Chasm: How to Drive Your Early-Stage Start-Up to Scale (Columbia Business School Publishing, 2025), Edward G. Amoroso provides an indispensable guide for start-ups looking to get off the ground and scale up to the next level. Getting to the chasm, as he illustrates through dozens of real-world case studies, requires long-term vision. Founders must focus on their core belief system―not simply what they do but why they are in business in the first place. Buyers connect with start-ups based on shared beliefs, and any founding team that does not understand this secret will struggle to build relationships with customers. Amoroso shares field-tested guidance for businesses in different spaces and stages on crafting a compelling message, understanding customers, benchmarking against competitors, and leveraging what makes a company irreplaceable. For founders, venture capital teams, private equity firms, investors, and readers with an interest in entrepreneurship, Reaching the Chasm is the road map for early-stage start-up success. Learn more about your ad choices. Visit megaphone.fm/adchoices

Put on your best Elle Woods cosplay, readers, because today Jake and Brooke discuss the legal organization called the Alliance Defending Freedom. This Dobson creation continues to wreak havoc on all of our lives in big and small ways. Even if you've seen the John Oliver segment on it, you still don't hate them enough.References:Bragman, W. (2026, Jan 5). Experts Warn U.S. in Early Stages of Genocide Against Trans Americans. ImportantContext.com. https://www.importantcontext.news/p/experts-warn-us-in-early-stages-ofLast Week Tonight. (2025, May 12). Alliance Defending Freedom [Video]. HBO & YouTube. https://www.youtube.com/watch?v=sCAuHH5EYnELIttlefield, A. (2021, November 30). The Christian Legal Army Behind the Ban on Abortion in Mississippi. The Nation. https://www.thenation.com/article/politics/alliance-defending-freedom-dobbs/Ward, I. (2024, march 25). The Group Behind Dobbs Does Not Want to Talk About What Comes Next. Politico. https://www.politico.com/news/magazine/2024/03/25/head-of-alliance-defending-freedom-Kristen-Waggoner-speaks-on-mifepristone-00148565Music from #Uppbeat (free for Creators!):https://uppbeat.io/t/mood-maze/trendsetterLicense code: 9OT2MTBHWWSRZP5S Hosted on Acast. See acast.com/privacy for more information.

What Happens When a Startup Runs Out of Money | The Financial  Operator Podcast | Episode 76 What happens when you do everything right, and still run out of money? In this episode of The Financial Operator: Cash In, Chaos Out, Jen sits down with  Andrew Ackerman, Head of REACH Labs at Second Century Ventures, to unpack the  realities of startups, fundraising, and what actually separates the companies that survive  from the ones that quietly disappear. Andrew shares his firsthand story of building a startup that was gaining traction until a  single world-changing event erased a signed term sheet overnight. From there, the  conversation expands into what founders really need to understand about capital,  leverage, timing, and decision-making. This episode covers: • What to do when funding disappears at the worst possible moment • Why "just take the money" is often the smartest early decision • The difference between venture-backed startups and traditional businesses • When fundraising should (and should not) be your full-time job • Why testing ideas cheaply beats building the wrong thing perfectly • The traits Andrew sees consistently in founders who succeed • How to find the one clear message that makes customers stop and listen If you're building a startup, considering raising capital, or trying to decide whether growth  should be funded or earned, this conversation will give you clarity without hype.  Watch now for a grounded, real-world look at startups, money, and making better  decisions earlier. ⏱️ Timestamps 00:00 Introduction & Guest Welcome 00:26 The Moment Andrew's Startup Ran Out of Money 02:10 Why Early Funding Can Disappear Overnight 03:20 "Just Take the Money": Lessons on Leverage 04:18 Which Businesses Should (and Shouldn't) Raise Venture Capital 06:57 Equity, SAFEs, and Convertible Notes Explained 08:37 When Founders Should Start Fundraising 11:47 Andrew's Path From Founder to Investor 16:14 Inside Accelerators and Early-Stage Investing 20:16 The Traits Andrew Sees in Successful Founders 25:32 Why Stories Teach Better Than How-To Guides 28:52 Testing Ideas Before Spending Real Money 33:39 Renting vs. Buying in the Early Stages 36:18 Finding the One Message That Stops Customers 45:03 Final Advice for Founders 49:00 Andrew's Book & Where to Find Him To connect with Andrew Ackerman's website: https://www.andrewbackerman.com Buy "The Entrepeneur's Odyssey" here: https://www.amazon.com/Entrepreneurs-Odyssey-Approach-Startup-Success/dp/1032883545/ref=tmm_pap_swatch_0 Don't forget to subscribe for the latest podcast episodes and insights from @mkbcfo Do you have your own financial or business growth questions for MKB?  Visit: Website: https://mkbcfo.com Instagram: https://www.instagram.com/mkb_cfo/ Facebook: https://www.facebook.com/mkbcfo LinkedIn: https://www.linkedin.com/company/mkbcfo #StartupLife #VentureCapital #Entrepreneurship #FounderJourney #StartupFunding #BusinessGrowth #RiskManagement #CashFlow #Innovation #TheFinancialOperator

Sit The F*ck Down and IntegrateKelle and Josh discuss the often overlooked yet crucial topic of integration in spirituality. They define integration as the process of allowing the work you've done to settle into your body, consciousness, and energy. Joshua shares his personal journey of learning to shift from a state of constant 'doing' to one of 'being,' highlighting the challenges and resistances he faced.Key Topics Include:Sharing experienceImportance of self-careProactive restWhen to pull backTrue healingSpiritual addictionDetached guidanceSpiritual coachingSlowing downAppreciating progress00:00 Welcome to Spirit Sherpa00:25 Shoutout to a Loyal Listener00:58 Introduction to Integration01:34 Early Stages of Integration02:22 Personal Integration Challenges03:04 The Importance of Downtime03:37 Josh's Integration Journey05:26 Spiritual Addiction and Realizations07:17 The Role of the Warrior Persona10:39 Balancing the Warrior and Mystic17:20 Kelle's Post-Surgery Experience19:41 The Challenges of Post-Surgery Recovery20:07 The Importance of Self-Care21:42 Reflecting on Work and Life Balance23:05 Embracing Inspiration and Energy24:00 The Role of a Spiritual Teacher25:52 Balancing Client Outcomes and Self-Worth29:01 Slowing Down and Honoring Your Body34:16 The Resistance to Integration39:02 Concluding Thoughts and EncouragementKeywords:feeling stuckhow to get unstuckspiritual growthpersonal growthself awarenessshadow workspiritual awakeningenergy healinginner resistancelack of claritylife transitionsidentity shiftego deathself sabotagehealing journeyspiritual coachingtransformational coachingwoo spiritualityenergetic blocksemotional healingmindset shiftcritical thinkingself development podcastspiritual podcastconsciousness expansionhealing traumapersonal evolutionlaw of attractionmanifestation blocksself masteryspiritual businessalignmentintuitionbreaking old patternsawakening journeydoing the inner workspiritual entrepreneurstuck in lifefear of changeself worthIf you would like to learn more please book a Discovery Call here: https://kellesparta.com/discovery-call/Licensing and Credits:“Spirit Sherpa” is the sole property of Kelle Sparta Enterprises and is distributed under a Creative Commons: BY-NC-ND 4.0 license. For more information about this licensing, please go to www.creativecommons.org. Any requests for deviations to this licensing should be sent to kelle@kellesparta.com. To sign up for, or get more information on the programs, offerings, and services referenced in this episode, please go to www.kellesparta.com

Trying to form early biotech partnerships but unsure when to say yes, when to push back, or when to walk away? In this episode, host Elaine Hamm, PhD, welcomes back Renee Williams, PhD, MBA, returning to the show as Chief Business Officer at Signify Bio. Drawing from her experience on both sides of the table (as a pharma dealmaker and now an early-stage biotech leader) Renee shares hard-earned insights on how founders can approach partnerships strategically without losing focus, time, or control of their company's story. In this episode, you'll learn: How to evaluate early partnership opportunities and decide which ones are worth your limited time, capital, and attention. Why focus is the most valuable currency for early-stage biotech, especially for platform companies facing constant “what else could this do?” questions. Practical guidance on MTAs, pilot studies, and proof-of-concept work, including how to structure collaborations so they move you closer to a real deal—not just more experiments. Whether you're navigating your first pharma conversation or refining how you partner as a growing biotech company, this episode offers clear, experience-driven advice to help you build partnerships that accelerate progress instead of distracting from it. Links: Connect with Renee Williams, PhD, MBA, and check out Signify Bio. Connect with Elaine Hamm, PhD, and learn about Tulane Medicine Business Development and the School of Medicine. Check out our previous episode with Renee. Connect with Ian McLachlan, BIO from the BAYOU producer. Check out BIO on the BAYOU. Learn more about BIO from the BAYOU - the podcast. Bio from the Bayou is a podcast that explores biotech innovation, business development, and healthcare outcomes in New Orleans & The Gulf South, connecting biotech companies, investors, and key opinion leaders to advance medicine, technology, and startup opportunities in the region.

In this podcast, experts Tiffany A. Traina, MD, FASCO, Kevin Kalinsky, MD, MS, FASCO, Mark E. Robson, MD, FASCO, and Rebecca Shatsky, MD discuss data for CDK4-6 inhibitors, PARP inhibitors, and immune checkpoint inhibitors in the management of early-stage hormone receptor-positive, HER-2-negative breast cancer.

Why Are Water Testing Methods Dangerously Outdated - And What's the Fix?Tired of stitching together Crunchbase, overpriced reports, and "a guy who knows a guy"? I built the fix. 50 Founder Seats. Join the waitlist: leviathandata.io

Episode 96 On December 31, 1986, just hours before Puerto Rico would ring in the New Year, flames tore through the luxurious Dupont Plaza Hotel and Casino in San Juan. What began as a labor dispute escalated into one of the deadliest hotel fires in U.S. history, killing 97 people and injuring more than 140. In the aftermath, investigators would uncover arson, negligence, ignored safety recommendations, a chaotic evacuation, and a legal battle that reshaped fire codes across the hospitality industry. In this episode, we examine: The labor tensions and strike that set the stage for disaster The timeline of the fire and how it spread so rapidly How smoke and toxic gases became the primary killers Failures in life safety systems, egress, and emergency planning The investigation that quickly identified arson Criminal charges against arsonists Massive civil litigation and code reforms that followed Lessons learned in the context of other hotel/casino fires of the era The Crime to Burn Patreon - The Cult of Steve - is LIVE NOW! Go join and get all the unhinged you can handle. Click here to be sanctified.  Inner Sanctum Acknowledgments: Eternal gratitude to our Inner Sanctum patrons, Melanie Curtis, Jenny Mercer and Laura Pisciotta, for helping us bring light to the stories others would rather leave in the ashes. Listener discretion is advised. Background music by Not Notoriously Coordinated  Get your Crime to Burn Merch! https://crimetoburn.myspreadshop.com Please follow us on Instagram, X, Facebook, TikTok and Youtube for the latest news on this case. You can email us at crimetoburn@gmail.com We welcome any constructive feedback and would greatly appreciate a 5 star rating and review.  If you need a way to keep your canine contained, you can also support the show by purchasing a Pawious wireless dog fence using our affiliate link and use the code "crimetoburn" at checkout to receive 10% off. Pawious, because our dog Winston needed a radius, not a rap sheet.  Sources:  Video & Documentary Sources Dupont Plaza Hotel Arson Investigation. Señor Onion's Archives. YouTube, April 13, 2021. https://www.youtube.com/watch?v=9JyUjUoX_so Dupont Plaza Hotel Arson of 1986. Señor Onion's Archives. YouTube, October 21, 2024. https://www.youtube.com/watch?v=tJsFLgxuDJ8 Government / Technical / Legal Reports Nelson, Harold E. “An Engineering Analysis of the Early Stages of Fire Development — The Fire at the Dupont Plaza Hotel and Casino — December 31, 1986.” NBSIR 87-3560, National Bureau of Standards, Center for Fire Research, U.S. Department of Commerce, April 1987. Levy, Harold M. “The Dupont Plaza Hotel Fire Litigation: A Case Study in Cooperative Defense.” Alternatives to the High Cost of Litigation, Vol. 7, No. 12, December 1989, pp. 215–233. José Francisco Rivera-Lopez, Plaintiff, Appellant, v. United States of America, Defendant, Appellee. U.S. Court of Appeals for the First Circuit, 4 F.3d 982, September 15, 1993. https://law.justia.com/cases/federal/appellate-courts/F3/4/982/525384/ (Note: First Circuit Local Rule 36.2(b)6 — Unpublished opinions may be cited only in related cases.) News & Contemporary Coverage (1987) “Teamsters Dispute with Dupont Plaza Dates Back Four Months.” UPI Archives, January 13, 1987. https://www.upi.com/Archives/1987/01/13/Teamsters-dispute-with-Dupont-Plaza-dates-back-four-months/7070215305413/ Brossy, Julie. “A Dupont Plaza Bar Boy Was Charged Today With…” UPI Archives, January 14, 1987. https://www.upi.com/Archives/1987/01/14/A-Dupont-Plaza-bar-boy-was-charged-today-with/8362537598800/ Hernandez, Moises. “Suspect in Hotel Fire Was Honored for Saving ‘Many Lives.'” UPI Archives, January 14, 1987. https://www.upi.com/Archives/1987/01/14/Suspect-in-hotel-fire-was-honored-for-saving-many-lives/2708537598800/ Gaulin, Edward J. “Defendants Plead Guilty in Dupont Plaza Hotel Fire.” UPI Archives, April 24, 1987. https://www.upi.com/Archives/1987/04/24/Defendants-plead-guilty-in-Dupont-Plaza-Hotel-fire/8801546235200/ Wilentz, Amy. “A New Year We'll Never Forget.” TIME, January 12, 1987. https://time.com/archive/6708028/a-new-year-well-never-forget/ Features, Retrospectives & Later Reporting Tepfer, Daniel. “A Vacation in Paradise Turns into Fiery Hell.” CTPost, Updated December 30, 2011. https://www.ctpost.com/news/article/a-vacation-in-paradise-turns-into-fiery-hell-2432149.php Reference / Encyclopedia & Summary Sources Dewey, Joseph. “Dupont Plaza Hotel Fire.” EBSCO Knowledge Advantage Research Starters, 2022. https://www.ebsco.com/research-starters/law/dupont-plaza-hotel-fire “Dupont Plaza Hotel Arson.” Grokipedia. https://grokipedia.com/page/Dupont_Plaza_Hotel_arson

As Barry Manilow's recent lung cancer diagnosis reminded us, a persistent cough, chest pain, shortness of breath may be more than just annoying symptoms. In this episode, we explain the signs you shouldn't ignore, what testing and treatment may look like, and how hope is still part of the story.  https://bit.ly/4szFIiaIn this Episode:02:21 - Tips for Longevity from People in their 90's - Naomi Rose & Physical Fitness04:48 - Avocado Salsa: Marriage of Guacamole and Pico de Gallo05:47 - Barry Manilow's Lung Cancer Diagnosis07:05 - Review of Lung Anatomy, Lung Cancer Overview, Differences between NSCLC and SCLC 09:32 - What Increases Our Risk of Lung Cancer?10:35 - Lung Cancer Signs and Symptoms to Watch For12:49 - Treatment of Lung Cancer - Reasons for Hope15:46 - Cancer Survivorship: How to Lower Your Risk of Cancer Returning and Signs not to Ignore18:57 - Discussion with Charlie: Historical Smoking, Persistent Cough24:04 - 27 y.o. Alexa Bekkerus Self-Written Obituary - How She Found Peace Dying with Metastatic Breast Cancer29:21 - OutroSupport the showGet show notes and resources at our website: every1dies.org. Facebook | Instagram | YouTube | mail@every1dies.org

Send me a text (I will personally respond)Are you struggling to transition from founder-led sales to a scalable sales-led model in your cybersecurity startup? Wondering if hiring a team of reps is really the fastest way to drive growth, or if there's a better approach? Curious how senior sales leadership involvement early on might speed up your journey to true product-market fit? If so, this episode is packed with insights for you.In this conversation, we discuss:

AP correspondent Haya Panjwani reports on a singer getting cancer surgery.

After surgery, many people with stage I to stage III hormone receptor-positive breast cancer take tamoxifen or an aromatase inhibitor for five to 10 years. This has been the standard of care for the last 25 years. At the 2025 San Antonio Breast Cancer Symposium, UCLA scientist Dr. Aditya Bardia presented results on giredestrant, a new oral selective estrogen degrader/downregulator (SERD) that offered better disease-free survival — how long people live without the cancer returning – than tamoxifen or an aromatase inhibitor. Listen to the episode to hear Dr. Bardia explain: how giredestrant is different from the two other available SERDs if giredestrant could be combined with a CDK4/6 inhibitor giredestrant side effects what the results mean for people diagnosed with early-stage hormone receptor-positive breast cancer

What happens when you’re diagnosed with breast cancer at 42, while running a business, raising a family, and just married? Today, Dorothy talks with Gaylyn, a longtime Rose patient and community volunteer, who found a lump in her breast, advocated for herself, and learned what it means to lean on others. Key insights from this episode: How early detection shaped her journey What it means to accept help Finding strength through connection with others Support The Rose HERE. Subscribe to Let’s Talk About Your Breasts on Apple Podcasts, Spotify, iHeart, and wherever you get your podcasts. Key Questions Answered 1. How did Gaylyn first connect with The Rose? 2. How did Gaylyn’s breast cancer diagnosis process unfold? 3. How did having previous medical records help her diagnosis? 4. How did Gaylyn advocate for herself during her diagnosis and treatment? 5. What treatment did she undergo for breast cancer? 6. What role did her husband play during her treatment? 7. What are some emotional and practical challenges Gaylyn faced during treatment? 8. What advice does Gaylyn share for women going through breast cancer or similar experiences? 9. How does Gaylyn feel about sharing her experience and helping others? 10. What lessons did she learn about saying ‘no’ and setting boundaries during her battle with cancer? 11. How did her faith and community support impact her journey? Timestamped Overview 00:00 Early Mammogram Advocacy Success 06:00 Rapid Surgery Decision 07:34 Skipping Chemo for Early Stage 12:37 They Can't Fix It 15:19 Grant Yourself Grace 16:14 Self-Care Through Adversity Lessons 20:50 Scars as Milestones of Healing 25:10 Entrepreneurial Challenges Amid Illness 26:12 Embrace Support Graciously 32:11 Embrace Vulnerability 33:08 Embrace Authentic Emotions OpenlySee omnystudio.com/listener for privacy information.

Joshua Goldberg, Co-Managing partner at Nath, Goldberg & Meyer – the #1 ranked patent law firm for biotech and pharmaceutical technologies joins Enterprise Radio.… Read more The post Why early-stage patent decisions can make or break future licensing deals appeared first on Top Entrepreneurs Podcast | Enterprise Podcast Network.

Natalie's revisiting some of the most-read Baggage Reclaim posts from the past 20 years in this new Between the Sessions series. In this minisode, Natalie talks about the issue of wanting to go back to the beginning of a relationship instead of recognising the reality of who we're involved with and what that might mean. Read the original articles and comments Leave a voice note: https://www.speakpipe.com/baggagereclaim  Support the podcast and leave a tip: https://baggagereclaim.ck.page/products/podcast  Break The Cycle  Relevant links and resources on the topic Dating Your Imagination: The Fantasy Trap in the Early Stages of Dating Despite 'Good Points', We Deal With the Consequences of People Coming as Full Packages 'Entanglement' and what happens when we look outside ourselves to feel good Letting Go of a Relationship That Doesn't Exist  

This episode dives deep into the shifting landscape of SaaS growth, investment philosophy, and leadership with Klee Kleber, former Dell and Rackspace executive and co-founder at Build Group.Klee Kleber shares why he prefers the "long game" model over traditional VC, explains the math behind durable businesses, talks about the importance of relentless execution, and how empathy, self-awareness, and diversity drive lasting success. From stories of luck at Dell to building customer love at Rackspace and the bold ambition of Topwater, this episode is packed with pragmatic wisdom for SaaS founders, operators, and investors.Key Takeaways00:00 Building for Impact and Permanence03:12 "Strategic Investing and Growth Playbooks"06:40 "Efficient Growth Through Discipline"12:47 "Separate Division for Innovation"15:14 Apple's Strategy: Innovation & Adaptability19:21 "Scaling After Market Fit"20:32 Obsessed Founders: Numbers & Customers23:57 "Teamwork Drives Effective Leadership"27:49 "Commit, Focus, Scale Success"30:08 Exit Strategy Driven by Management34:24 "Growth Limits and Opportunities"39:31 "Customer Loyalty Drives Growth"40:16 Target Audience Traits Matter46:10 "Defining ICP: Human vs. MBA"49:45 AI vs Doctor: Diagnosis Revolution51:44 "Leadership, Innovation, Differentiation Challenges"54:29 "AI-Driven Growth with Topwater"Tweetable Quotes"You can't diversify your way to success—you can only retain your wealth through diversification. To build a company, you have to go all in." — Klee Kleber"Start with customer love—and radiate out from there. Obsess over the customers who love you, and the referrals will follow." — Klee Kleber"Relentless execution is what differentiates great companies from those that just do okay or even good." — Jeff Mains"Efficiency isn't boring—it's the secret to durable, compounding growth that actually lasts." — Klee Kleber"Most business to me is treading water, being disciplined, not burning, testing ideas, measuring like crazy, until you find the live wire." — Klee Kleber"Self-aware founders who build teams that compensate for their weaknesses are the ones who scale and thrive." — Klee KleberSaaS Leadership LessonsBuild for the Long Game – Focus on investments and company-building strategies that aim for durability and lasting impact, not just quick wins.Efficiency is a Competitive Advantage – Discipline in metrics like LTV/CAC and payback periods creates sustainable growth, instead of hoping for a lucky exit.Relentless Execution Beats Strategy Alone – Luck may start the journey, but relentless, focused execution is what converts opportunity into success.Balance Data with Customer Contact – Great founders marry spreadsheet discipline with real human customer feedback and empathy.Embrace Diverse Perspectives – Teams with varied backgrounds, skills, and viewpoints consistently outperform homogenous ones and spark true breakthroughs.Self-Awareness Multiplies Leadership Impact – Know your personal strengths and weaknesses; build teams that complement you and delegate accordingly.Guest Resourcesklee@buildgroup.comhttps://www.buildgroup.com/https://www.linkedin.com/in/kleekleber/Episode SponsorThe Captain's KeysSmall Fish, Big Pond –

Buoyed by record crude oil flows and the expectation of further growth in Western Canada, Enbridge has been sanctioning more pipeline expansion projects and discussing plans to add more capacity.

Origins host Beezer Clarkson,  LP at Sapphire Partners and co-founder of OpenLP, and Nick Chirls, GP at Asylum Ventures, dive into their recent conversation with Kyle Samani, Founder and Managing Partner of Multicoin Capital. They discuss their learnings on crypto, including why Nick is more bullish on bitcoin than Kyle, and how LPs conceptualize investing in firms like Multicoin. They also break down why people who came up as Crypto traders and investors are uniquely positioned to excel in early stage venture.Learn more about Sapphire Partners: sapphireventures.com/sapphire-partnersLearn more about OpenLP: openlp.vcLearn more about Asylum Ventures: asylum.vcLearn more about Multicoin: multicoin.capitalFor a monthly roundup of the latest venture insights, including the newest Origins episodes, subscribe to the OpenLP newsletter – delivered straight to your inbox: subscribe.openlp.vcCHAPTERS:0:00 Welcome to Origins1:02 Is Bitcoin an Unproductive Asset?1:56 The Problem With Web3.03:49 Assessing Crypto Managers As an LP6:21 The Hard Part Isn't Buying Bitcoin, It's Holding It8:21 Trained In Crypto, Excelling In Traditional Markets

Send us a textIf you're posting, branding, and “working on your website” but not actually closing clients, this episode is your wake-up call. Sales strategist Katie Nelson (The Sales Catalyst and CEO of Sales Uprising) breaks down why so many first-time founders drown in marketing while starving their business of cash. If you've ever avoided sales because you're introverted, uncertain, or afraid of hearing “no,” this conversation will change how you think about selling forever.

Amy and Margaret discuss two new studies on boys and their lives online—in social media and gaming—and how today's digital culture shapes boys' mental health, relationships, and ideas about their bodies and about masculinity. We discuss why gaming fills social and emotional needs for many boys, why the time spent may be of more concern than the content, and how parents can stay involved without over-policing. You'll learn practical ways to become an “ask-able” parent, set boundaries, and how to know whether their time spent online is more harmful than helpful. Here are links to some of the resources mentioned in the episode: Gottfried, Jeffrey & Sidoti, Olivia for Pew Research Center: ⁠⁠Teens and Video Games Today⁠⁠ Clair Cain Miller & Amy Fan for the NYT: ⁠⁠“How Video Games Are Shaping a Generation of Boys, for Better and Worse”⁠⁠ Oxford Internet Institute: ⁠⁠“Violent Video Games Found Not to Be Associated with Adolescent Aggression⁠⁠ Boston Children's Digital Wellness Lab: ⁠⁠Pulse Survey: Digital Gaming and Social Interaction⁠⁠ Claire Cain Miller for the NYT: ⁠⁠It's Not Just a Feeling: Data Shows Boys and Young Men Are Falling Behind⁠⁠ Federica Pallavicini et. al for Cyberpsychology, Behavior, and Social Networking: ⁠⁠The Effects of Playing Video Games on Stress, Anxiety, Depression, Loneliness, and Gaming Disorder During the Early Stages of the COVID-19 Pandemic: PRISMA Systematic Review⁠⁠ Wenliang Su et. al for Computers in Human Behavior: ⁠⁠Do men become addicted to internet gaming and women to social media? A meta-analysis examining gender-related differences in specific internet addiction⁠⁠ Kirk M. Welker for JAMA: ⁠⁠Video Games—Cognitive Help or Hindrance?⁠⁠ Kara Alaimo for CNN Health: ⁠⁠What your teenage son is really seeing on social media, according to new survey⁠⁠ Common Sense Media: ⁠⁠⁠Boys & Gaming: What Parents Need to Know⁠⁠⁠ ⁠⁠Fresh Take: Jean Twenge⁠⁠ ⁠⁠Why Kids Get Obsessed—And Why It's a Good Thing⁠⁠⁠⁠⁠ ⁠Laura Vanderkam's time-tracking spreadsheet⁠⁠ ⁠⁠Sign up for our newsletter to get monthly recs/goodies from us! ⁠⁠ We love the sponsors that make this show possible! You can always find all the special deals and codes for all our current sponsors on our website: ⁠⁠⁠https://www.whatfreshhellpodcast.com/p/promo-codes/ Get 50% Off Monarch Money, the all-in-one financial tool at ⁠www.monarchmoney.com/FRESH Ready to raise money-smart kids? Start now with your first month FREE at acornsearly.com/FRESH! Head to GigSalad.com and book some awesome talent for your next party, and let them know that What Fresh Hell sent you. boys and social media, boys and gaming, boys mental health, digital culture and masculinity, parenting boys online, raising boys in the digital age, video games and boys, healthy screen time for kids, social media effects on boys, parenting advice for tweens and teens, online friendships and gaming, emotional development in boys, helping boys navigate technology, positive masculinity, how to talk to kids about gaming, setting digital boundaries, boys body image online, supporting boys' wellbeing, parenting in the digital world, tech and teen mental health, What Fresh Hell podcast, mom friends, funny moms, parenting advice, parenting experts, parenting tips, mothers, families, parenting skills, parenting strategies, parenting styles, busy moms, self-help for moms, manage kid's behavior, teenager, tween, child development, family activities, family fun, parent child relationship, decluttering, kid-friendly, invisible workload, default parent Learn more about your ad choices. Visit podcastchoices.com/adchoices

Tons of entrepreneurs claim to be "scaling" their business, but when you look under the hood, they're actually just growing fast. And there's a big difference. Growth can be exciting, but without structure, systems, and the right leadership in place, it's not sustainable. That's where Allison Maslan comes in. She's built and scaled 10 companies across multiple industries, and as the CEO of Pinnacle Global Network, she's helped more than 150,000 founders and leadership teams do the same—earning a spot on the Inc. 5000 Fastest-Growing Private Companies list four years running. In this episode, we dig into why so many founders fail to scale, unpack Allison's 5 Pillars of Scale framework, and explore how to turn big vision into an operational reality your team can rally behind. Key Takeaways 00:00 Intro 00:54 Why Scaling is an Overused Word 02:25 Early-Stage vs. Late-Stage Scalability 04:09 Why So Many Founders Fail to Scale 06:59 The SCALEit Framework Explained 10:35 The 5 Pillars of Scale (S.C.A.L.E.) 11:22 Can SCALEit & EOS Work Together? 14:15 Creating a Strategic Vision That Drives Growth 20:59 Balancing Big Vision with Tactical Reality 25:02 Case Study: Vision Turned Into $100M+ Growth 26:50 Balancing Long-Term Vision with Rapid Change 33:45 Delegation vs. Abdication 43:30 Defining Hiring Metrics for Scalable Success 48:28 Mental Shifts That Enable Massive Growth 57:02 Advice for New Entrepreneurs Getting Started Watch on YouTube: https://youtu.be/LFABrEvlf0Q Let's Connect: IG: https://www.instagram.com/bradweimert YouTube: https://www.youtube.com/@Beyondamillion TikTok: https://www.tiktok.com/@beyondamil Twitter: https://twitter.com/BradWeimert FB: https://www.facebook.com/profile.php?id=100089061999787

Read the original article and comments Leave a voice note: https://www.speakpipe.com/baggagereclaim Support the podcast and leave a tip: https://baggagereclaim.ck.page/products/podcast Break the Cycle of Emotional Unavailability course Book Natalie for a private session Relevant links and resources on the topic Future Faking, Fast Forwarding and Being The Good Girl/Guy. When You're Too Concerned With How You Look Future Faking is partly about using intentions to enhance self-image Understanding Why You Find It Hard To Get Over Someone Who Future Faked and Fast Forwarded Fantasy vs Reality: When you struggle to differentiate between what was real and what wasn't The Pop-Up Relationship: The Temporary Romance That Expires & Never Develops Recovering from Somebody Doing a U-turn on Their Feelings or Proclaimed Intentions We Need To Talk About: 'Ghosting' in the Early Stages of Dating Did they just do a U-turn? When a person overestimates their level of interest or capacity for commitment Ep. 223: The Gaslighting of Future Faking Ep. 251: Spotting a Romance Scammer Ep. 211: Too good to be true? Ep. 140: The Truth About Lies Ep. 135: In the Beginning… There Were Assumptions