ACSH Science Dispatch

GLP-1 drugs like Ozempic are transforming weight loss and diabetes management. But no good deed goes unpunished, and the manufacturers of these medicines now face a wave of lawsuits, with plaintiffs claiming they weren't warned about rare but sometimes serious side effects. Is this litigation driven by solid evidence, or are the tort lawyers out for yet another unearned payday? Let's take a look.

Science thrives on challenge, not conformity. Many scientists would agree with that statement, yet they often equate truth with expert consensus, at least when talking to the public. Since scientific disputes are really settled by evidence and not a show of hands, perhaps it's time for experts to abandon consensus and focus on a more accurate concept—convergence.

The COVID-19 pandemic exposed systemic weaknesses in our disaster preparedness infrastructure. Despite prior warnings, politics and apathy nurtured a response system that prioritized appearances—e.g., a national stockpile of rotting N-95 masks—over effective interventions. Perverse incentives encouraged officials to drag their feet when time was short, a failure leading to poor coordination and resource allocation that couldn't counter a global viral threat. We desperately need reforms that will work with human nature during a disaster instead of against it. What do those look like? Let's dive in.

The perennial vegan worrywarts at Physicians Committee for Responsible Medicine (PCRM) have once again warned that grilled hot dogs increase colorectal cancer risk. But this potential harm is wildly overstated—as it has been since it first emerged from the dark recesses of nutritional epidemiology many years ago. Your absolute risk of colorectal cancer remains quite low, and the occasional ballpark hot dog probably doesn't move the needle in either direction. Let's take a closer look.

Nobody denies that science is plagued by an epidemic of fraudulent and politicized research, nor that it wastes billions of taxpayer dollars. But is the problem severe enough to justify completely eliminating public funding for scientific research? Let's take a look.

"Sugar is addictive." It's a widespread, well-researched claim—and it's probably false. The assertion oversimplifies complex eating behaviors driven by an even more complicated cluster of influences. While sugar intake can stimulate reward pathways in the brain similar to drugs, it lacks several key characteristics of true addiction, leading to a less satisfying but more accurate conclusion: we've picked a convenient scapegoat instead of solving our real nutritional problems.

Can eating well pave the way to healthier, more vibrant golden years? The answer is "maybe," based on a recent study surveying how diet affects disease risk as we age. Let's break down the paper's results.

Organic food is a $52 billion enterprise, fueled by wealthy consumers convinced they're avoiding the alleged harms endemic in "industrial agriculture." Is there any science behind that belief, or is it just high-priced marketing hype? Let's take a closer look.

A resurgence of heroin in the black market might be contributing to a significant drop in fentanyl-related overdose deaths, with provisional CDC data showing a 24% decline in overall U.S. overdose deaths by September 2024. Could this shift, alongside harm reduction efforts like increased naloxone distribution, be reducing fatalities? Let's take a look.

Health and Human Services secretary Robert F. Kennedy Jr. has controversially promoted vitamin A as a treatment for measles, despite research showing it can be toxic in high doses and is no substitute for vaccination. Kennedy's view is particularly ironic given his criticism of genetically engineered Golden Rice, a crop designed to boost...vitamin A levels in developing countries.

The rapid expansion of legalized sports betting in the US has fueled a significant increase in gambling addiction, with calls to helplines surging and treatment providers overwhelmed by demand. While the industry generates substantial revenue, it also imposes hidden costs on society, including financial ruin, mental health problems and strained public resources. Now the question is, can we bring this emerging public health crisis to heel?

Gatorade claims its alkaline water will hydrate you into peak performance, but it's just pricey H2O bolstered by clever marketing. Save yourself a few bucks and drink the stuff from the tap instead.

During the recent battle over FDA's decision ban the use of Red No. 3 in food and ingested drugs, few commentators answered a fundamental question: why do food makers use dyes in the first place? The press framed the answer as a corporate ploy to sell more candy, but the story's a bit more complicated than that. Let's take a closer look.

With prescription opioid overdoses plummeting and no more pharma companies to sue, America's drug warriors are running out of bogeymen to justify their crusade against pain killers. The solution? Redefine responsible opioid use as a disorder and turn millions of chronic pain patients into addicts—at least on paper.

The medical journal The Lancet recently published a detailed consensus statement classifying obesity as a disease. The statement has engendered both widespread support and criticism. Did the expert panel make the right call? Let's take a closer look.

USDA's Thrifty Food Plan aims to help low-income Americans eat well without breaking their modest budgets. It's an altruistic attempt to promote public health. But this bureaucratic project to promote nutrition lacks what so many other government programs do: the ability to incentivize healthy living at scale.

Researchers at the Mayo Clinic recently published a study perpetuating the myth that opioid prescriptions launched the ongoing drug overdose epidemic. Two ACSH experts took the clinic to task for sloppy data analysis designed to justify a predetermined conclusion about the risks of painkillers. Let's take a closer look. Article discussed: Opioid Bogeymen: ACSH Advisor Takes Mayo Clinic to Task, for Its Pain Management Fairytale Subscribe to the ACSH Dispatch newsletter to get our stories in your inbox.

Non-steroidal anti-inflammatory drugs (NSAIDs) are widely used to control pain. They are typically quite effective and safe to use as directed. But many people can't rely on them owing to their sometimes serious side effects—including an increased risk of heart attack. In short, NSAIDs are essential drugs with real limitations. Let's take a look at the most popular of these medicines. Article discussed: NSAIDs: Pick Your Poison Sign up for the ACSH Dispatch newsletter to get our stories in your inbox.

Despite significant decreases in cholesterol numbers, cardiovascular disease rates in the US have hit a standstill. Can we restart the decline, or have we reached the limits of our ability to combat this persistent condition? Story discussed: Chasing Cholesterol

A trucker who took CBD oil for pain control was abruptly fired after failing a drug test that found THC, the primary psychoactive compound in marijuana, in his system. Although the product was marketed as THC free–a claim the man verified with the manufacturer–it was not and federal law mandated his termination. It's yet another case of awful drug laws and even worse science harming good people. Story discussed: Supreme Court THC Case Highlights Our Flawed Drug Laws Follow us on X: @ACSHorg, @camjenglish

As part of a challenge study conducted during the pandemic, 34 healthy volunteers were deliberately infected with SARS-CoV-2 to assess the potential cognitive impacts of COVID-19. Everything about the experiment, from its timing to its design, was suspect and almost certainly unethical.

Recent headlines declared that the artificial sweeteners Xylitol and Erythritol could increase your risk of stroke and heart attack. Now that the media excitement has died down, let's take a closer look at the study behind the headlines. Does it really implicate these sugar substitutes as a threat to heart health? Not exactly.

Pain patient advocates recently made their case to the FDA during an agency listening sessions, arguing that the federal government has launched an unjustified crusade against prescription opioids. Rather than reduce overdose deaths or drug abuse, the nationwide crackdown on painkillers has only left millions of patients to suffer without recourse. Are regulators finally waking up to this reality?

Scientific American's endorsement of Kamala Harris for president ignited a ferocious debate in the science community. Is she the best choice for advancing science, as her supporters contend, or is it unwise for researchers and scientific institutions to back political candidates?

The emerging Make America Healthy Again (MAHA) movement has resurrected the well-worn accusation that food and drug companies dictate US public health policy. How true is this claim? And do the leaders of the MAHA campaign have their own conflicts of interest? They sure do.

The American Academy of Pediatrics (AAP) seems to be in an awkward spot. The group fears that children could be exposed to hormone-disrupting pesticides through food. However, it also endorses the use of puberty blockers and cross-sex hormones—drugs that disrupt normal hormone production—in gender-dysphoric youth. Are the AAP's divergent standards justified, or is this just a classic case of hypocrisy?

Scientists have learned much about COVID-19 over the last four years. But several aspects of the pandemic remain to be fully explained, including Long COVID: a chronic condition that can cause or contribute to some 200 health effects throughout our bodies. A recent study suggests that fibrin, a key component of blood clots, plays a role in the development on Long COVID, and may lead to effective treatments for the condition. Let's take a closer look at the results.

Some patients taking weight-loss drugs like Ozempic are beginning to report slower or no weight loss as their bodies build up a tolerance to the medication. Does this spell trouble for obese people looking to slim down long-term? Dr. Chuck Dinerstein reports his personal experience with the so-called Ozempic plateau.

Scientists often think they're smarter than they are because of their narrow academic expertise, according to a new study. Recent history is littered with corroborating examples in which experts made false declarations about COVID-19 and refused to acknowledge their errors. What drives this hubris, and how should the public respond to it?

America's anti-opioid crusade routinely denies chronically ill patients access to adequate pain control, relegating them to an agonizing existence. Many of these individuals would rather die than withstand the anguish, and some advocates of physician-assisted suicide say we should help these patients end their lives. Is this an ethical solution to the crisis of untreated pain? We have our doubts.

If you're too busy for an hour-long gym session, "exercise snacking" – short bursts of intense activity over several minutes – may help you stay fit despite your jam-packed schedule. That's according to a new study, but how compelling are the results? Let's take a look.

A recent study claimed that excessive sitting–all too common in our modern, hyper-connected world–is more deadly than smoking and HIV. The solution, the researchers claimed, is a novel creation known as the treadmill desk, which allows people to exercise during their work days. How truthful is all this? Not very.

America's prohibitionist assault on prescription opioids has left an untold number of chronically ill patients without access to adequate pain control, encouraging them to use illicit substances like heroin or even take their own lives to end their suffering. Some drug policy reformers say the solution to this tragic situation is outright legalization of all drugs. How well would that policy actually work? Let's take a look.

As social creatures, humans often synchronize with each other in watching movies, dancing in groups and mirroring the behavior of our romantic partners. Could this synchronicity actually influence whom we find attractive? A new study says—maybe.

The blockbuster weight-loss drug Ozempic has ignited a ferocious debate over the ethics and efficacy of treating obesity with medication. Oddly, this intense ideological battle has glossed over perhaps the most important question we should answer: how does the drug impact individual patients? Our Director of Medicine Dr. Chuck Dinerstein is working to correct that oversight by documenting his experience with Ozempic.

Most health scares you see in the headlines are generated by low-grade epidemiology research that correlates food or chemicals exposures with negative health outcomes. A recent review employing a new analytical tool highlighted some of the critical problems in this research by looking at studies reporting health risks linked to red meat consumption. Let's take a look at their findings.

A recent study, predictably followed by alarmist headlines, suggested that the sweetener xylitol may increase the risk of cardiovascular complications and blood clots. As usual, there is much more to the story—including the fact that xylitol is perfectly safe for most people to consume as a sweetener.

Mental health medications are a blessing to many people. But they sometimes come with undesirable side effects, including significant weight gain. A recent study suggests that a high-fat, low-carb ketogenic diet could help some patients manage their weight while taking psychiatric drugs. Let's take a closer look at the results.

Our children face a wide range of health and safety risks these days: choking, fentanyl poisoning and school shootings, just to name a few. But put aside such paltry concerns because Consumer Reports (CR) has identified the real threat to your kids: Lunchables. These safe, affordable prepackaged meals may actually expose your children to potentially harmful levels of lead, the activist group claims. As usual, CR is pushing a baseless health scare to raise money.

Holden Thorpe, editor of the once-prestigious academic journal 'Science,' has made many strange claims in recent years, including the assertion that anybody involved in or adjacent to science (a journalist, policy wonk and perhaps even an activist) is actually a scientist. ACSH's Dr. Henry Miller calls shenanigans.

The Supreme Court is poised to decide a case that could seriously restrict the authority of federal regulatory agencies. Some legal observers say the decision will put power-hungry bureaucrats in their place, though others maintain the decision could force judges and members of Congress to make scientific determinations they aren't qualified to make. Let's talk to a legal scholar to make sense of the "Chevron deference."

Recent research suggested that our lungs contain tiny (micro- and nano-sized) plastic particles, courtesy of our widespread use plastic consumer products. Let's take a deeper look at the study to determine how serious of a health risk we're up against. As always, the media didn't tell you the whole story.

There's yet another adulterant showing up in illicit fentanyl in cities across North America: medetomidine—a drug used for sedation, analgesia, and muscle relaxation, typically in veterinary settings. How dangerous is the drug, and what can be done to stop its recreational use? Let's take a look.

Which is more dangerous, sunscreen or the sun itself? Should we just wear sun-protective clothing instead? As summer approaches, let's examine the latest research and separate sun facts from myths before heading to the beach.

Tort lawyers regularly bring litigation against pesticide companies alleging that their products cause devastating diseases. Of course, our genetic makeup profoundly influences our risk for certain medical conditions, including those allegedly caused by pesticide exposure. Yet this reality rarely gets the attention it deserves in court. Let's take a closer look at the science the lawyers would rather ignore.

Microplastics are everywhere, including in your arteries, and they heighten your heart attack risk! So declared a slew of recent headlines reporting on a study in the New England Journal of Medicine. Let's examine all the science reporters ignored in their rush to get hyperbolic stories out the door.

A recent study found that controlled periods of fasting could hold the key to unlocking a longer, healthier life. Do we finally have evidence that skipping meals reverses aging, or is the situation more complicated than that?

Artificial Intelligence (AI) plays an increasingly prominent role in modern life, medicine included. While the technology promises to improve health care in many ways, it also carries potentially serious risks. That raises a critical question: when AI harms patients, who's responsible? Join Cameron English and Dr. Barbara Billauer on Episode 70 of the Science Dispatch podcast as they discuss AI in medicine with Stanford Law professor Michelle Mello:

Tinnitus–a vexing ringing in one or both of your ears not caused by external sound–impacts some 740 million adults globally. A recently FDA-approved treatment appears poised to help many of these patients reduce the severity of their symptoms and thereby boost their quality of life. Let's take a closer look at this therapy to find out how it works.

The standard argument for restricting patient access to pain medications is that these drugs frequently lead to addiction. A large body of research contradicts that claim, though it's doubly absurd when directed at people afflicted by terminal (and often very painful) illnesses. They sometimes have only weeks or months to live, yet they're denied pain medicine in the name of fighting opioid dependence. Such absurdity has to stop.

Unlike other public health emergencies, the COVID-19 pandemic had unmistakably partisan overtones. Politics exerted an unhealthy influence on how governments, scientists, reporters and ordinary Americans responded as SARS-CoV-2 swept across the world and upended our lives for the better part of four years. What went wrong and what can we learn from it? Dr. Paul Offit joins us to answer those critical questions.