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Cameron is the founder of Among the Lilies a Podcast for women “who are tired of pretending and ready to be real!” Cameron discusses her remarkable health journey and the transformative impact of a carnivore diet on her life. Cameron shares her experiences with chronic pain, migraines, Ehlers-Danlos syndrome, and other health issues, as well as her journey to health and empowerment through the carnivore diet. Instagram: Among_the_lilies YouTube: @cfradd Other: Patreon.com/amongthelilies Website: Cameronfradd.com Timestamps: 00:00 Trailer and introduction. 04:25 Faith's benefit in healing process, dealing with depression. 08:23 Diagnosed with multiple conditions, changed diet drastically. 09:55 Food quality impacts health, fermentable food affects reflux. 15:30 Improved health on carnivore diet for 4 months. 18:51 Gut health impacts disease, surprising case study. 20:43 Shock, happiness, sugar addiction. 24:01 Man's recovery and wife's support transformed life. 27:05 Chronic pain improved by warm climate visits. 30:37 Neurontin sedating, empowering to take control. 34:31 Phase out coffee during carbohydrate transition for improvement. 36:13 Animated speaker discusses diet in public engagements. 40:37 Continuous glucose monitors reveal impact of food. 42:10 Eating habits change to two meals daily. 45:22 Where to find Cameron. See open positions at Revero: https://jobs.lever.co/Revero/ Join Carnivore Diet for a free 30 day trial: https://carnivore.diet/join/ Carnivore Shirts: https://merch.carnivore.diet Subscribe to our Newsletter: https://carnivore.diet/subscribe/ . #revero #shawnbaker #Carnivorediet #MeatHeals #HealthCreation #humanfood #AnimalBased #ZeroCarb #DietCoach #FatAdapted #Carnivore #sugarfree
Episode 148: Leg CrampsFuture Dr. Weller explains the pathophysiology, management, and prevention of leg cramps. Hector Arreaza adds comments and anecdotes about leg cramps. Written by Olivia Weller, MS4, American University of the Caribbean School of Medicine. Comments by Hector Arreaza, MD.You are listening to Rio Bravo qWeek Podcast, your weekly dose of knowledge brought to you by the Rio Bravo Family Medicine Residency Program from Bakersfield, California, a UCLA-affiliated program sponsored by Clinica Sierra Vista, Let Us Be Your Healthcare Home. This podcast was created for educational purposes only. Visit your primary care provider for additional medical advice.Definition: Known also as “Charlie horses,” leg cramps are defined as recurrent, painful, involuntary muscle contractions. They can last anywhere from seconds to several minutes, with an average of nine minutes per episode. They are usually nocturnal and thus may be associated with secondary insomnia. Location: A muscle cramp can happen in any muscle in the body, but they occur most commonly in the posterior calf muscles, but they can also involve the thighs or feet. They are more common in women than men and the risk increases with age.Although they are experienced by 7% of children and up to 60% of adults, the exact mechanism remains unknown and there is no definitive treatment at this time. PathophysiologyThere is one leading hypothesis for nocturnal cramps that occur in the posterior calf muscles, and it is related to your sleeping position. When you are laying down in bed your toes are pointed which causes passive plantar flexion while the muscle fibers are shortened maximally. This causes uninhibited nerve stimulation with high-frequency involuntary discharge from lower motor neurons, which causes cramping. Another possible etiology is nerve damage because neurologic conditions such as Parkinson's disease are associated with a higher-than-normal incidence of cramps. Peripheral neuropathy, or damage to the connection between motor nerves and the brain can lead to hyperactive nerves when they are not being properly regulated. Thus, diabetes mellitus is a major risk factor for nocturnal cramps due to the high blood sugar levels damaging the small blood vessels which supply the muscles. Decreased blood flow has also been attributed as a cause of leg cramps. People with diseases that affect their vasculature, such as varicose veins or peripheral arterial disease also have a higher incidence of leg cramps. Decreased blood flow to the muscles means less delivery of oxygen and nutrients to the muscles which makes them more susceptible to fatigue. Muscle overuse is one of the dominant explanations for cramping. This can be related to doing too much high-intensity exercise without adequate stretching before and after. Pregnant women have added weight which puts extra strain on the muscles, along with sitting or standing for long periods of time, poor posture and flat feet. Notably, when we age, our tendons naturally shorten and they cannot work as hard, or as quickly which makes them more susceptible to overuse. Additionally, there are mineral deficiencies such as magnesium and potassium or decreased levels of B and D vitamins. With this in mind, people with renal failure that are on hemodialysis have an increased risk of nocturnal leg cramps. And finally, we have medications, some of which are related to mineral deficiencies. The main contributors are statins, diuretics, conjugated estrogens, gabapentin or pregabalin, Zolpidem, clonazepam, albuterol, fluoxetine, sertraline, raloxifene, and teriparatide (analog for parathyroid hormone). Management and preventionThere is no magic treatment to make them go away immediately, however, there are different remedies you can try to help facilitate. My Grandma told me about an old wives' tale, that if you put a bar of soap in your bed at your feet while you sleep, you won't get cramps at night. Maybe it works by the placebo effect, maybe there's a mechanism going on there I don't understand who knows, I'll have to do a study on it. If you get them very often, you can keep a foam roller or a heating pad next to your bed in preparation for when they come. Stretching the muscle is known to be very effective, as well as applying heat or ice to the affected area. You can also try massaging the muscle with your hands or getting out of bed to stand or walk around. Elevating the leg while laying down in bed can also be beneficial. In terms of prevention, you can try out different sleeping positions to see if one works better for you. If you usually sleep on your back, you can stick a pillow under your feet to help keep your toes pointed upward. Or, if you sleep on your stomach you can try to keep your feet hanging off the bed. Another tip is loosening the sheets or blankets around your feet. Daily stretching, especially before and after exercise as well as before bed is useful. Make sure to exercise, stay hydrated, and limit your alcohol and caffeine consumption. You also want to wear supportive shoes or use orthotic inserts in your shoes, especially if you spend lots of time on your feet during the day. Medications/supplements: Since various deficiencies can cause cramps, one way to prevent them is to take supplements such as magnesium, vitamin D, and B12 complex. And as a last resort, you can try medications. Calcium channel blockers such as diltiazem or verapamil have been used, and muscle relaxants including Orphenadrine (Norflex®) and Carisoprodol (Soma®). Gabapentin is an anticonvulsant commonly used as a neuropathic pain medication; this used to be used to treat leg cramps but later it was found that they can actually increase the frequency of muscle cramps so they are no longer used. Quinine was also used for many years to treat leg cramps; however, it is no longer recommended because of drug interactions and serious hematologic effects such as immune thrombocytopenic purpura (ITP) and hemolytic uremic syndrome (HUS). Summary: Leg cramps are common, the pathophysiology is unclear, but may be related to problems with blood flow, the nervous system, sleeping position, and muscle overuse. Treatment includes nonpharmacologic therapies such as changes in sleeping position, heat, and massaging; and medications/supplements that may be useful include Carisoprodol (Soma®), diltiazem, gabapentin (Neurontin), magnesium, orphenadrine (Norflex®), verapamil, and vitamin B12 complex.____________________________Conclusion: Now we conclude episode number 148, “Leg Cramps.” Future Dr. Weller explained that the etiology of leg cramps is multifactorial. Some theories about why leg cramps happen include poor circulation, muscle overuse, dysfunctions in the nervous and musculoskeletal systems, electrolyte imbalances, mineral deficiencies, and more. Some therapies were discussed, including changes in position while sleeping, massage, heat pads, and medications such as calcium channel blockers, muscle relaxants, and supplements of magnesium and Vitamin B12. Gabapentin is a medication that can cause leg cramps, but some sources recommend it as a treatment as well. This week we thank Hector Arreaza and Olivia Weller. Audio editing by Adrianne Silva.Even without trying, every night you go to bed a little wiser. Thanks for listening to Rio Bravo qWeek Podcast. We want to hear from you, send us an email at RioBravoqWeek@clinicasierravista.org, or visit our website riobravofmrp.org/qweek. See you next week! _____________________References:Leg Cramps. Cleveland Clinic. (2023, May 6). https://my.clevelandclinic.org/health/diseases/14170-leg-crampsAllen, R. E., & Kirby, K. A. (2012, August 15). Nocturnal leg cramps. American Family Physician. https://www.aafp.org/pubs/afp/issues/2012/0815/p350.htmlMayo Foundation for Medical Education and Research. (2023, March 2). Night leg cramps. Mayo Clinic. https://www.mayoclinic.org/symptoms/night-leg-cramps/basics/definition/sym-20050813Royalty-free music used for this episode: Simon Pettersson - Good Vibes_Sky's The Limit_Main. Downloaded on July 29, 2023, from https://www.videvo.net/
Visit: https://nursing.com/140meds to request your free copy of "140 Must Know Meds" Generic Name Gabapentin Trade Name Neurontin Indication Seizures, peripheral neuropathy, neuropathic pain, prevention of migraines Action Exact method of action unknown, may play a role in stabilizing neural membranes Therapeutic Class Analgesic adjuncts, anticonvulsants, mood stabilizers Pharmacologic Class None Nursing Considerations • May cause suicidal thoughts, confusion, depression, drowsiness, ataxia, facial edema, hypertension • Monitor pt closely for changes in behavior and depression • Assess seizure activity • Assess pain level • Patient should take medications exactly as prescribed
Vaxxinity's John Krayacich likes taking big swings at big indications. He's played key roles on the teams that launched Lipitor, Lyrica, and Neurontin, which have had measurable impacts on global populations of people suffering from cardiovascular disease, CNS disorders, and pain. He found those opportunities at companies like LEO, Novartis, Parke Davis, and Pfizer. Now, Krayacich is taking big swings at a new set of incredibly challenging candidates—immunotherapeutic vaccines for neurodegenerative and chronic diseases like Alzheimer's, Dementia with Lewy Bodies, Multiple System Atrophy, Parkinson's, Migraine, and Hypercholesterolemia. On this episode of the Business of Biotech, the Chief Business Officer shares his inspiration and strategy for seeing therapeutics for big, global patient populations through the commercial finish line. Subscribe to the NEW #BusinessofBiotech newsletter at bioprocessonline.com/bob for more real, honest, transparent interactions with the leaders of emerging biotech. It's a once-per-month dose of insight and intel that you'll actually look forward to receiving! Check it out at bioprocessonline.com/bob!
Natasha is a mum, serial entrepreneur, a transformation coach and hypnotherapist who was diagnosed with Multiple Sclerosis and was treated with Cortisone and Neurontin for years until she found a way to reverse her paralysis with Rapid Transformational Therapy. Her mission in life is to inspire, teach and motivate people to take control of their health, businesses and lives. She believes everything is fixable and figureoutable and has created an amazing ten step program which she shares on Breaking Free near the end of the episode.Discussed in this episode:Natasha's first flare up of Multiple Sclerosis was misdiagnosed (1:50)How steroids helped the flare ups but had very unpleasant after-effects (8:30)Natasha's world before Multiple Sclerosis (11:00)Paralysis hits for the first time (14:00)Discovering the damage Cortisone and Neurontin was having on Natasha's brain cells (18:30)Rapid Transformational Therapy with Marissa Peer becomes the answer to Natasha healing her flare ups naturally (21:00)Natasha trains in hypnotherapy and heals herself while she is snowed in and paralyzed while alone on holiday (25:10)The power of meditation with Joe Dispenza (28:05)The ten step program to having a healthier life is created (31:00)The power of fasting, sunshine and Ketosis with Dr, Courtney Hunt (37:10)References:Marissa Peer - Rapid Transformational TherapyDonna Eden - Energy medicineLouise Hay - You can Heal Your LifeDr. Courtney Hunt - KetosisJoe Dispenza - meditationsConnect with Natasha:Linkedin: https://www.linkedin.com/in/natasha-quariab-ba42612b/Instagram: https://www.instagram.com/thenatashaq/Website: https://www.hypnotherapyme.com/aboutLet's connect!FacebookInstagramTwitterLinkedInWebsite Hosted on Acast. See acast.com/privacy for more information.
#wynonajudd #damarhamlin #hrv #mentalhealth #neurofeedbackpodcast Jay Gunkelman is the man who has read well over 500,000 Brain Scans and he discusses on the NeuroNoodle Neurofeedback and Neuropsychology Podcast Mental Health & HRV News: Wynona Judd, Damar Hamlin, The Neuro Alphabet Letter G & H as well as Brain Anatomy Other Topics Include: The Stages of Grief, Depression, Acceptance, Hope, Geniculate, Asperger's, Autism, Medial Geniculate, Cochlea, B.A.R.E Testing for infant hearing, Globas Palladus, Gamma, Yoga Master, Zen Master, Dali Lama, Gabapentin, Nerve Pain, Neurontin, Hebenula, Theta beta training neurofeedback, lateral hebenula, Motivation, Addictions, Pain, Tinnitus, Hearing Loss, Hearing Aids, Hippocampus, Memory processing, Amygdala and Hippocampus joined --- Send in a voice message: https://anchor.fm/neuronoodle/message Support this podcast: https://anchor.fm/neuronoodle/support
This episode is also available as a blog post: https://youarewithinthenorms.com/2022/12/19/nsaid-tylenol-neurontin-and-the-fabricated-sense-of-pain-relief/ --- This episode is sponsored by · Anchor: The easiest way to make a podcast. https://anchor.fm/app Support this podcast: https://anchor.fm/norman-j-clement/support
Pfizer, una de las mayores empresas farmacéuticas del mundo, fue sorprendida recientemente cometiendo algo absolutamente escandaloso: un fraude Les pillaron manipulando datos para hacer creer que su medicamento Neurontin era más eficaz de lo que realmente era. Este vídeo explica lo que ocurrió y por qué es tan importante. *** Por favor comparte este audio con todos tus amigos y familia para que me ayudes a llegar a más personas! *** Este podcast es traído a ustedes por Anchor.fm, la plataforma gratis de spotify que pone tu podcast en todas las grandes plataformas de streaming para que el mundo te escuche. Anchor.fm es muy sencillo de usar, si sabes mandar un mensaje de texto y grabar una nota de voz, entonces sabes usar anchor.fm y lo mejor de todo, es que si a tu podcast le va bien, a cambio de un par de anuncios publicitarios en tus publicaciones, Anchor.fm te premia y te paga por tu talento. Hablando de pagarle a la gente por su talento, te comento que Patreon.com es la plataforma que uso para subir mis contenidos, patreon es una plataforma de crowdfunding donde gente genial como tu premia a otros como yo por su talento. Si te gusta mi trabajo y quieres ayudarme a mejorar los contenidos puedes volverte parte de mi equipo como patrocinante en la plataforma de crowdfunding en Patreon. https://www.Patreon.com/albertozambrano —donde por menos de lo que te cuesta un cafe puedes informarte, educarte, desestresarte y distraerte. Hago asesorias y consultorías como gerente estratégico de negocios! Únete a KUCOIN y usa mi Bot de CryptoTrading https://www.kucoin.plus/land/register/r/rJZTQEJ Unete a Binance y gana conmigo comisiones de hasta 40% por cada trade que hagas www.binance.com/en/register?ref=HT0DTYA7 Donaciones en Crypto: USDT: 0xe5b6a6dc1611349fd279ea5e48a406fdc37a523a BTC: 1AeJtkJysWYJfDpW8XoBiNCtUwPmAbfsec ETH: 0xe5b6a6dc1611349fd279ea5e48a406fdc37a523a (ERC20 o BSC) *** Crea contenido usando inteligencia artificial con Jasper.ai https://jasper.ai?special=yd11po4 ICP: 3a53ae0c61d2f90c4592dc131d7f730978bc004043613e22cb79a4fe85673c1d ADA: DdzFFzCqrht7dQHjcMPqpTGDUzrVHeZbvUz9mZXzScJMJ2KbDxg73aPqwCecGSBbkbWyfaaByxhGjBRL14hDhbCXYM11bgGFGsSrQjBe BNB: 0xe5b6a6dc1611349fd279ea5e48a406fdc37a523a (BSC) DOGE: D9BLJfT63JyJ1UU219hC38r51zA8UNy68t BTT: TTjaAN8iBV9o2s429snE5PSvsZrqjSKTF9 VET: 0xe5b6a6dc1611349fd279ea5e48a406fdc37a523a Tengo un canal de telegram bastante activo donde posteo cosas random https://t.me/AlbertoZambranoMD --- Send in a voice message: https://anchor.fm/albertozambrano/message
Real Life Pharmacology - Pharmacology Education for Health Care Professionals
On this podcast episode, I discuss gabapentin (Neurontin) pharmacology, adverse effects, drug interactions, and much more! Gabapentin's GI absorption is a little wacky. I discuss on the podcast the clinical effects that this may have on our patients. Renal elimination is critical to gabapentin. Worsening renal function will significantly impact the action of the drug. CNS sedation can be a problem with gabapentin, especially in combination with other CNS depressants. I discuss this further on the podcast.
Yet another study shows that Neurontin is a poor substitute for prescription opioids, so why do physicians continue to prescribe it? Twitter recently put a warning on an ACSH obesity story. Is social-media censorship here to stay? Join our directors of bio-sciences, chemistry, and medicine Cameron English, Dr. Josh Bloom, and Dr. Chuck Dinerstein as they break down these stories on episode 23 of the Science Dispatch podcast. The Devil You Know - Neurontin's Massive Flop as an Opioid Alternative Wanna hear something sickening? Neurontin, a drug developed for epilepsy and used off-label for neuropathic pain, had its sales grow 250% between 2004 and 2019. Why? We don't have 250% more epileptics. No, it's because the drug is being forced down the throats of people who can no longer get sufficient pain relief. The result? Abuse and also more overdose deaths. Just another chapter in our psychotic war against legitimate opioid drugs and the people who need them. Censorship? Twitter Puts A 'Warning' on ACSH Obesity Article Continuing its trend of unjustified censorship, Twitter put a "warning" on one of our recent tweets "so people who don't want to see sensitive content can avoid it." This protects nobody, but it denies the public access to credible health information.
This week's podcast is about one of the world's top selling drugs, Neurontin (generic name Gabapentin). And it centres on an extraordinary court case which for the very first time accused a drug company, Pfizer and its subsidiary Warner Lambert, of racketeering, under the Racketeer Influenced and Corrupt Organisations Act, a piece of legislation that was actually brought in tackle organized crime. The company had been accused of encouraging doctors to use Neurotonin not just for its approved use, but for several unapproved uses, something that is known as off-label marketing and is illegal in the US. It had attempted to market the drug for bipolar disorder, neuropathic pain and migraine. Despite the fact that in the judge's words there was “little or no scientifically accepted evidence that Neurontin is effective for the treatment of bipolar disorder, neuropathic pain or migraine”. Detailed detective work by the plaintiff's expert witnesses revealed how data was distorted and inconvenient evidence buried to suggest the drug was effective. And the shocking discoveries in this decade old trial continue to be highly relevant for patients and doctors today. Telling this story is Dr John Abramson, who was one of the expert witnesses in the trial, who spent nearly two years forensically examining thousand of documents to uncover the truth. John is based at Harvard Medical School, where he teaches health care policy. John has written several books about the pharmaceutical industry and consults as an expert in litigation involving the industry. You can sign up to the podcast mailing list and be first to know when a new episode is published at whatyourgpdoesnttellyou.com and also find out more about the pod there. The host of the podcast, Liz Tucker is an award winning medical journalist and former BBC producer and director. You can follow Liz on Twitter at @lizctucker and read her Substack newsletter about the podcast at liztucker.substack.com If you would like to support this podcast you can do so at patreon.com/whatyourgpdoesnttellyou or via PayPal at whatyourgpdoesnttellyou.com
“I'd like to try Lyrica, but I worry about if I ever had to come off. Should I try it?” For today's Ask The Coach episode, I'm answering this question sent in by Sarah in the UK. When treating fibromyalgia, we have to attack it from two sides. The first is addressing the fibromyalgia itself and the amplification of pain signals; the second is treating the pain that your fibromyalgia amplifies. In most cases, fibromyalgia medications are more helpful than harmful and can be a valuable tool to break the pain cycle. That said, the question of medications is complex and impossible to cover in detail in a podcast episode. Tami's primary focus for this answer will be on fibromyalgia medications that address the amplification of pain signals, how they work, and the most important aspects you'll want to consider. In this episode, Tami discusses the FDA-approved medications for fibromyalgia, the fact that no single drug is capable of managing all fibromyalgia symptoms, Tami's two-pronged approach to treating fibromyalgia, the main goal of fibromyalgia medications, Lyrica's history and previous versions, how Lyrica and Neurontin work to reduce our experience of our pain, common side effects of Lyrica, physical dependency versus addiction, how serotonin and norepinephrine affect pain levels, why the anti-depressants Savella and Cymbalta also help to address fibromyalgia symptoms, the mode of action of other anti-depressants that are sometimes prescribed for fibromyalgia, Cymbalta is known for being challenging to come off of, the importance of very slowly weaning off of medications, the gradual process Tami used when she was ready to come off of her medications, why we hear more stories about negative experiences, the fact that there's no morality in taking medication, and more. Note: This episode is not meant to be medical advice. Every person and every situation is unique. The information you learn in this episode should be shared and discussed with your own healthcare providers. To learn more about the resources mentioned in this episode, visit the show notes. For daily doses of hope, inspiration, and practical advice, join Tami on Facebook or Instagram. Need a good book to read? Download Tami's books for free. Ready to take back control of your life and health? Schedule a complimentary consultation with a Certified Fibromyalgia Coach®.
Download the cheat: https://bit.ly/50-meds View the lesson: https://bit.ly/GabapentinNeurontinNursingConsiderations Generic Name Gabapentin Trade Name Neurontin Indication Seizures, peripheral neuropathy, neuropathic pain, prevention of migraines Action Exact method of action unknown, may play a role in stabilizing neural membranes Therapeutic Class Analgesic adjuncts, anticonvulsants, mood stabilizers Pharmacologic Class None Nursing Considerations • May cause suicidal thoughts, confusion, depression, drowsiness, ataxia, facial edema, hypertension • Monitor pt closely for changes in behavior and depression • Assess seizure activity • Assess pain level • Patient should take medications exactly as prescribed
Akutte ryggsmerter! Legge seg ned eller ut å løpe? Neurontin? MR hot or not? Dr. Brox svarer. Aktuelle ressurser Oppsummering akutte ryggsmerter - Brox (Helsebiblioteket, 2021) Videoer om undersøkelse ved Fagbokforlaget Videoer om undersøkelse ved UiO For LiS-leger kan denne podcasten bidra til å oppnå læringsmål om diagnostikk av rygglidelser i FMR, ortopedi og revmatologi: FMR-048, ORT-018, REV-010. Ansvarlige for podcasten er legene Sigrid Skatteboe, Niels Gunnar Juel og Andreas Saga Romsdal.
Are you a woman in your midlife years struggling with the debilitating effects of fibromyalgia? If so, you are not alone. In fact, an estimated 8% of the adult population worldwide suffers from this condition. Fortunately, there is hope. In this episode of The Hormone Prescription Podcast, we talk to Dr. Rodger Murphree, an expert on hormones and fibromyalgia, about some of the latest research on this topic. During the show, Dr. Murphree reveals: Clinically proven protocols for correcting the multiple symptoms of fibromyalgia and chronic fatigue syndrome. Why conventional treatments for fibromyalgia often fail The symptoms of fibromyalgia and how they can be warning signs for other underlying health conditions The diet and lifestyle changes that can help to address the root causes of fibromyalgia And more! If you are ready to start feeling better and want to learn more about fixing the root causes of fibromyalgia, then this episode is for you. Tune in now and let's get started on your journey to recovery! [00:00] Life is short. If you're not careful, you'll miss it. Dr. Roger Murphy is my guest today, and we're gonna talk about fibromyalgia and what it has to do with your hormones. If you're suffering with this, you've likely had a long road and you're missing a lot of your life and it just shouldn't be. So we're gonna tell you how to get out of the predicament you're in, in this episode. [03:12] Oh, I'm so excited to be here. I, you know, last time we got together just enjoyed our conversation so much. And I learned some things that, that I didn't know, and I was really delighted to be able to learn something new and uh, yeah. Thank you. I'm so excited to be here. [03:27] Yeah. Super excited to talk about fibromyalgia. It's actually a part of my story. I don't focus on it too much, but those who know me and listen to my podcast probably have heard me talk about that. I had that. I just had horrible unrelenting pain in many places on my body on a consistent basis. And before I got on my journey, in addition to weighing 243 pounds and being super tired and it's really something that's hard for the general public to understand even those people who have it because they go from doctor to doctor not being diagnosed. And there's so few doctors who really understand what fibromyalgia is all about. So can we just start by talking about what it is and how might someone suspect that they have this? [04:20] So there's writings about fiber Maia in the, the 18 hundreds. Uh, and um, over the years there have been more and more writings about it, but it didn't, you know, it didn't happen to really hit the, the map, you know, be put on the map until 1990 when the American college of rheumatology came out with the criteria for the diagnosis. So it's been around, you know, it's been around for 30 something years is, uh, something that people know about. But unfortunately we still have a lot of misconception about fibromyalgia. We have doctors who still don't acknowledge that, that it's a real entity. Those that do acknowledge that we do have a thing called fibromyalgia. Don't really know how to treat it. They've largely given up on it. [05:12] Uh, but fibromyalgia is a syndrome like Aero bowel syndrome or metabolic syndrome. It's a group of symptoms that people have in common. And we give it a name to describe those symptoms, but fibromyalgia, which affects about 8% of the adult population worldwide. This is what the estimates are anywhere from four to 8%, primarily women between the ages of 35 and 60. It is an illness characterized by diffuse achy, sometimes disabling pain, fatigue, brain fog, irrit bowel, resto syndrome, low moods anxiety. So it's a very long list of symptoms that come underneath this title called fibromyalgia. [05:59] Yes. And there are specific criteria to be diagnosed with it, but like Dr. Roger said, it's really hard to get a diagnosis. There aren't that many doctors that are that familiar with it. And what is a mainstream treatment typically of fibromyalgia? [06:16] . It's just so frustrating that, you know, it makes me laugh because it's so really so sad, but in conventional medicine, as you know, so well, it's all about treating symptoms. Oftentimes that's really what the focus is. And you know, there's a time and a place for that. Thank goodness. You know, we, we, we have the wherewithal and we have the prescription medications and the surgeries and things that we need to be able to treat some of these things. But in fibromyalgia, the conventional medicine protocols, relying on drug therapy alone have been a dead end. The surveys show this, that even the American college rheumatology on their own website, now they've taken this down, but they used to say that they don't recommend that patients take anti-inflammatories pain, medications, sleep aids are anti-seizure medications because they're not effective long term. [07:12] And they have potential side effects. And where we're at right now in conventional medicine is that most conventional doctors will tell their patients that you just have to learn to live with it. And they, they don't believe you can overcome fibromyalgia because what they've seen day in and day out is that there are patients that they've recommended these different medications, Neurontin, and Ella, and AlTiN these other things they don't improve. And their take on it is, well, we've given you the drugs that are approved for fibromyalgia, and you're really no better, you know, four or five years later, it's really your it's your fault. And you're just gonna have to learn to live with it. So that's where we're at right now in conventional medicine. [08:24] Yeah, it's unfortunate. And I would say that's definitely a mainstream model cuz when I see people in my story too, includes this when you really get to the underlying root cause I find that it's extremely treatable. So talk about your approach. You've held a fibromyalgia summit. You've been specializing in this for years. You've written a book about it. You really are one of the gurus about fibromyalgia. [08:54] Hope. Well, so I have to go back a little bit. So 20 years ago when I had my first patient referred to me for fibromyalgia, I had no idea what I was getting into and you know, from your own journey and then from seeing patients, you, you kind of hear their symptoms and you think there's no way you can have this many things wrong with you. You mean you look normal. And then of course you look at their blood work and most of the time everything's normal. Their said rate CRP, their inflammatory markers normally are okay, but there's a tendency to look at this individual as a hypo contract and I'll be candid. That was my first reaction to my patient, Sheila Sheila Jones, who came to see me 20 years ago. But I started just working with her using just good sound nutrition and some functional medicine testing to find out that she had things wrong with. [09:43] She had candid to overgrowth and some food allergies and leaky gut. I started treating her and within three months, this illness that I didn't really know much about and her doctor said, we don't really know what it is, but here you hear some muscle relaxers and some pain pills come back in six months and we'll see how you do well. She got well, Karen in three months just doing some basic stuff that I would do on really kind of anybody is a functional medicine practitioner. [10:32] And I started just kind of bringing those different therapies together and then eventually realized that there's some really key things that if you get these key things right for the fibromyalgia patient, he or she usually is, she is going to have the best opportunity to overcome their fibromyalgia symptoms. And really the only way for someone fibromyalgia to be able to feel good again, long term is they gotta get healthy. And that sounds so simplistic. I realize that, but it's about finding and fixing the underlying causes of these symptoms. And then, so there's four key things that make up what I call the Murry method and the mur jumpstart protocols, which if you do these four things, you focus on these four things as a fibromyalgia patient, your odds of, of dramatic improvement are really good. [11:59] So fibromyalgia is just a name. That's all it is. So it doesn't cause the pain. It doesn't cause the low energy, it doesn't cause the insomnia or the poor sleep. It's just a name. And so what you wanna look at is, okay, what could be some of the triggers for chronic pain, low energy, brain fog, low moods and irritable bowel, resto sex syndrome. What's the common denominator? Well, the first common denominator is poor sleep. So we know with studies, it doesn't matter really to me, whatever your condition is. If you've got a chronic health condition, the place to start is making sure that you're able to get consistent deep restorative sleep. Cuz when you get that deep restorative sleep, that's when the body's repairing itself. [12:48] And what we see with fibromyalgia is a struggle to fall asleep and they struggle to stay asleep. So they all have sleep issues. They never feel refresh. They're not going into that deep Delta wave restorative sleep. And we know that if you're not getting consistent, good sleep, you're gonna have all the symptoms that I've mentioned in fibromyalgia. You're you're obviously gonna be tired, right? Lethargic. You're gonna have brain fog. We know that you increase your inflammatory chemicals by 40%, you create all sorts of stress in the body. Oxidative stress. [13:48] So it made sense to me, let's just get 'em sleeping through the night, right? And that's where I focus is the first thing is to make sure that they're able to consistently get that deeper store to sleep. And a big part of that for me, was realizing early on that everyone with fibromyalgia is low in this brain, chemical called serotonin. And that's, you know, we've had two drugs that have been approved for fibromyalgia, Illa and Alta, which are selective serotonin and no uptake inhibitors. But serotonin is the key for these people. [14:54] So they were not able to produce the serotonin that they needed. And when you're low in serotonin, your pain threshold goes down. And those with fibromyalgia have a condition called ALA Donia, which is low pain threshold. So their pain is magnified. And what I found is as I raised that serotonin by using five ay triptan and then high doses, but safe doses of vitamins and minerals and amino acids, I was able to get their serotonin levels up, which raised their pain threshold, lowered their pain, helped with their mental clarity. Their moods, uh, helped with irritable bowel cuz you have more serotonin receptors in your intestinal tract than you do in your brain. So by getting their serotonin levels up, I was able to help them with many of the symptoms associated with fibromyalgia, but probably the biggest one. [16:39] So many of us, you know, women at midlife have trouble with that. And particularly like you're describing with fibromyalgia this low serotonin that may be innate as well as the disruption in sleep causes all kinds of inflammatory cascades to be set off. And so that started really helping your patients to improve. [17:00] Well, so what I saw is that once I got them sleeping and, and five HTP was how I started that. So I'd have them take five HTP, 30 minutes for bed with a little bit of grape juice to release the, the glucose would trigger insulin response, which would help that five HTP get past the blood brain barrier and work quicker. So once they started taking the five HTP and started sleeping through the night, then the next thing that I had to work on was that these individuals have depleted their stress coping glands, the, the, uh, the adrenal glands. So stress becomes magnified. They they're deficient in cortisol, D H E a. [17:52] And so they would overdo it. They would, they would do things that they couldn't normally do. You know, if fibromyalgia robs you of so many things robs you of your health, that robs you of your social life, a lot of times, your intimacy, your career, you know, all these things are taken from you because you find with fibro, you really can't do a lot. If you try to do more than normal, you have these things called fibro flares where your symptoms are accentuated. [18:35] They could have more stamina and resistance to it. So it didn't really wipe 'em out when they encountered it. And that's when I started, when I had the, for a number of years, I had a medical practice where I had five medical doctors working with me and we use Corte. So we use cortisol, you know, prescription medication, very, as you know, it's a very safe dose. It's it's um, about a fourth or a fifth, the strength of prednisone, but we use Corte and we saw that patients now they could handle stress better. [19:25] Although I recommend that you get a particular type of adrenal glandular, it needs to be just cortex, whole glandular, adrenal supplements have not only the cortex, which is mainly cortisol DHA, but also have the me doula part of the adrenal, which is very stimulating, cuz it has adrenaline. And the worst thing you can do for these individuals is to hype them up. They can't tolerate that. They're their autonomic nervous system is already on overload. It's already hypersensitive. So for those you listening, make sure you're gonna get adrenal supplements. [20:30] Now the RDA that recommended dietary allowance is some 60 years outta date. And it's really just enough to keep you from getting scurvy or Berry Berry. You know, it's not, you know, it really ain't gonna do anything. That's why people take a multivitamin, a central or whatever. They never feel any different. They never look any different. You've gotta use high doses. What I call optimal daily allowance, which is sometimes 5,000 times stronger than the RDA recommended disease allowance [21:34] But we were using that protocol before every people really knew what it was. And we were seeing when we gave them these high doses of vitamins and minerals, that they slept better. They had less pain, they felt better mentally and physically, but UN you know, it wasn't feasible for people to come get an IV every week, travel 2, 3, 4 or five hours away. Like some people did between the cost and the inconvenience. It just, you know, it wasn't compatible. So years ago I developed a formula, a fibro formula, which has high doses of vitamins and minerals, all the B vitamins in the methylated form, malic acid, high doses of magnesium, which is a natural muscle relaxer, all the amino acids, which are the building blocks of the hormones that I know you talk so much about. [22:39] That is my new favorite wording for RDA is yeah. Recommended disease allowance. [22:48] why, I mean, you think about that. I know like the multivitamin I'm sure that you have you recommend right. Is, is, you know, probably got, I don't know, was 50 to a hundred milligrams of B2 in it. And which is what I think that's what 500 times stronger or a thousand times stronger than what the RDA is. And if you don't use these higher doses, people are just not gonna improve. [23:08] Right. I always talk to people about that. So listen up, you know, the one a day, Centrum, silver, it sounds great. They're cheap, but you don't want it. It's a waste of your time and your money. So I love that recommended disease allowance. I just had to say that. And you know, the other thing I wanted to share is that you mentioned Myers cocktails. They actually used to give the nutrients rectally like a Myers cocktail. They called it a Murphy drip on the battlefield in wars, going back a hundred years ago. So it's not new. [24:03] No, please. And you know, I think the thing is, I, I know you encounter this too. You're interacting with a patient and you're sharing with them the importance of vitamins and minerals. And they're giving you this look like how are vitamins and minerals gonna help me when I've been on Neurontin and I've been on oxycodone or whatever it is. I mean, they they've been on heavy duty pharmaceutical therapies. And you're, you're saying, you know, the only way really to do it is to get healthy and to get healthy. You know, you've gotta take these vitamins and minerals, but you need to do it in a dosage. That's gonna make a difference. [25:04] Know, even I saw my hairdresser selling vitamins and all these little gummies that you take, they're supposed to help your hair. And I'm just like, what? But it's so true. It's that simple. Y'all, it's the basics, you know, like Dr. Rogers talking about and nutrient support at high doses, optimal doses, not the recommended disease. Allowance is a key part of that. Yeah. It's a key part of healing. Anything really? [25:30] I think so. I think so, you know, people ask me, what's the number one supplement you'd recommend. And I would say, get the best multivitamin that you can, one that you like, you know, you're, if you like a li you know, if you can't take a pill, find a liquid, whatever it is, but get the best multivitamin that, that you can tolerate. That's where you put your money and then you build around that. Otherwise you're gonna be like the patients set Dr. Karen. And I see where they've got this big Santa Claus bag of supplements that they, you know, usually it's the spouse, you know, in my practice, it's, they're mostly female. [26:18] Seriously. I, that, I mean, you know, that makes me so sad because it's really, it's just diagnostic of our current medical system that, that isn't doesn't have the answers, but also Dr. Google. And so people are looking for information all over. And so what's lacking in the information, age is wisdom. So if you're listening to this, no matter what you've got to heal, vitamins and nutrients are a part of it, but you've gotta have be strategic about it. [26:52] So number four, but before I go there, you triggered this. I just wanna mention this yeah. That the, um, Janet trave, which she was a very prominent physician back in, well, she's the physician to Kennedy and Johnson mm-hmm and she wrote the trigger point manual. So bifacial manual. And in that book, there's, uh, I think there's two or three chapters. And all it is in those chapters is about vitamins and minerals and the role they play in reducing pain. And, you know, so this is not, this is not something that we don't know about. It's just something that's been ignored. You know? So this was being written about 50 years ago, 60 years ago. [28:00] So definitely your diet is super important. No doubt about it, but it's just as important. What you're able to absorb as it is what you eat. So what I have found is the fibromyalgia community is notorious notoriously deficient in these nutrients because of number one, poor diet, oftentimes, but even the individuals and you get these who are what I, what I call health nuts in a, in a very nice way who eat even healthier than I do, which I eat really, really healthy. And I know you do, but they eat. What I would think is even healthier than I do. And they're still just miserable. [29:03] They had these things that were preventing them from absorbing the nutrients in their foods. And also even, even being able to use the supplements, the nutrients that they were taking in a pill form, they couldn't even digest those because so many of them would have a problem where they would eat. They'd take their supplements and then have a dumping syndrome. They'd have to run to the bathroom. 70% of the people with fibromyalgia have irritable valve. And, and so I realized that we're gonna have to make sure that we clean up the diet that's important. So a low sugar, low carb diet is most effective for, for these individuals usually, but they also need be on digestive enzymes. That was the simplest quickest way to make sure that they were absorbing their nutrients and getting the most out of them is by getting them on a good digestive enzyme. [30:31] And you know, it's funny when I practiced mainstream medicine, I am guilty of that too. That fibromyalgia was this enigma and it was untreatable and nobody knew what to do with it. And even with myself, I didn't know what to do and my physician didn't know what to do. And now I look at it from a functional perspective and I go, it's so super simple. You treat the cause. Yeah. And these are the causes and when you treat the cause the symptoms go away. So , how has your practice evolved since you, I mean, you came from more of a chiropractic background, right? [31:22] Yeah. It's it's, I mean, I never would've chosen fibromyalgia, who would be crazy enough to do that. and I love 'em. I mean, you know, so I, I think they're the most wonderful people in so many ways. They're very challenging, no doubt about it, but just like your complicated patients, once you figure out some of the common denominators, it becomes a much easier, but yeah, I started off as, just as a chiropractor and I had a very busy practice. [32:12] And then that started growing into my realizing that that was more fun than doing the hands on work. I really enjoyed the biochemistry mm-hmm and really started doing the training in functional medicine. And then I got kind of a reputation here in Birmingham, Alabama being a, a doctor who was really good with medical misfits. The people who'd been everywhere, tried everything or just wanted something different than conventional medicine. And, and I started getting referrals from the medical community and one of those was a patient with fibromyalgia. And when Sheila came to see me, I mean, again, my first thought was she's a hypochondriac, but the more I heard her story, I realized she's 35, she's a career. [33:29] . And so you've held a summit that people can still access on fibromyalgia and you've held several others. Tell everybody about all the resources that you have available. [33:39] Well, depending on when this airs, the fibromyalgia summit is being launched in may of this year 2022. And you can learn more about that@yourfibrodoctor.com. You can, but it's a free online summit. It's free. You can, there's 30 different specialists. We cover everything from insomnia and poor sleep to balancing neurotransmitters, to brain chemicals for anxiety and depression. We have presentations on IRO, bowel, leaky, gut food allergies, thyroid, which we hadn't really mentioned. I know that's a big one for you, hormone replacement therapy. So there's all sorts of, you know, various dynamics that go into rebuilding this individualized fibro. It's kinda like, um, peeling the layers of an onion. You know, you have to peel these layers away till finally you peel 'em all away. And there's this person who radiates health again. [35:02] Yes. And then don't you have, you have other books and you've got, tell everybody about all the, the goodies that you have for them. . [35:11] So in uh, October I'll be doing a super healthy lung summit and that's all gonna be about respiratory health, including long haul protocols. Mm protocols for asthma food allergies, seasonal allergies, Mo talk, all allergies, mold toxicity, mass cell histamine dominance. So that'll, that'll be out in October, 2022 and I've written five books. So three on fibromyalgia and then two, one book on, uh, heart disease, which your doctor won't tell you. And then one on anxiety and depression using orthomolecular medicine, which is vitamins minerals, amino acids, and essential fatty acids to treat mood disorders. [35:52] Boy, could we have a whole conversation about heart disease? What your doctor won't tell you [35:56] oh, so many medical myths out there, right? About, about cholesterol and, and all the, all the stuff that's out there that when you really look behind the, the smoke and the mirrors, you see that it's much you do about nothing, right? [36:10] Yes. So we'll have to do that on another episode, but this has been wonderful. You really have laid out a path for people to follow who are suffering with fibromyalgia or maybe for people who suspect that they have it, but they're not sure. Or they've gone from doctor to doctor and they're not getting a diagnosis. So thank you so much for that. If we are able to air this before the, your fiber summit airs will definitely have a link in the show notes, we'll try and get it out before then. But if not, you're, if it's after you can still access it and we'll have that link in the show notes for you, Dr. Rogers shared this quote with us before that we recorded the episode that life is short. If you're not careful, you'll miss it. And I love that. It's so true. [37:22] Well, just for more information about the jumpstart protocols, you can go to your fibro store.com and there's four free videos that are about 10 minutes, 10 minutes each, but it goes over in a little more detail than I could today about how and why these things work. And these are things you can buy anywhere over the counter. So, but the videos really go into a little bit more detail to explain how it all comes together. [37:46] Right. Thank you so much for these incredible resources. And thank you for listening to another episode of the hormone prescription with Dr. Kirin. I'll see you next week until then peace, love and hormones. Y'all thank you so much for listening. Learn more about Fibromyalgia by joining Dr. Rodger Murphree's The Fibro Summit: CLICK HERE Get Dr. Rodger Murphree's FREE Report: The Truth About Organic Foods & How to Dramatically Increase Your Mental & Physical Energy https://yourfibrodoctor.com/newreports/ Join The Hormone Bliss Challenge FEEL ENERGIZED, SEXY & CONFIDENT IN YOUR BODY AGAIN... IN JUST 5 DAYS. Discover How To Balance Your Hormones & Jumpstart Your Metabolism So That You Can Lose Weight & Regain Energy! CLICK HERE: https://bit.ly/hormonebalancebliss
Big Ideas: There are two different types of pain [1:49] – Both types of pain require different treatments to control. Somatic pain is the most common type that requires narcotic medication to treat. Nerve pain is the second type of pain. Narcotic medication does not work in the treatment of nerve pain, and it is often missed. Nerve pain requires nerve medication – gabapentin (also known as Neurontin) is the most common medication used for never pain management. Stabbing or burning pain, often localized in the feet and head is indicative of nerve pain. Quality of life for patients is directly related to pain management. The Hospice Comfort Kit [7:30] – Hospice provides a comfort kit for family caregivers filled with the most common medications used at the end of life to manage pain, breathing difficulties, and other common causes of discomfort. Have this comfort kit within 24 hours of the patient being placed on Hospice. If you encounter a need for medication to address pain or breathing issues and you do not have it available, it will lead to a stressful (and avoidable) situation for everyone. Once on Hospice we know there is going to be a decline in patient condition – but we don't know at what rate the decline will occur. Being prepared for this decline to happen quickly is essential. Pick one person in the family that will be in charge of administering medications – this should be whoever is most comfortable doing so. Have the Hospice nurse go over the medication in the comfort kit with the caregiver and practice administering medications and understanding the comfort kit on each visit until it is well understood. Trying to figure out what to use and how to administer it during a crisis situation is not the way to do it. Understanding the Pain Scale [11:16] – The pain scale is typically assessed by 1 to 10. 1 is no pain and 10 is the most pain a person can possibly be in. Pain is subjective. Pain needs to be kept at a 4 or below for optimal quality of life each day. When pain is going up, you have to stop that pain on its incline or control it because if it gets too high it will be almost impossible to bring down – this is how the human body works. Patients will sometimes hold off on taking medication until they really need it because it is something they still have control over, but it is too late if their pain is already too high. Assess their pain regularly and keep a logbook of their pain levels pre-medication and 45 minutes post-medication. You can't take medicine out of somebody, so administer pain medications incrementally until you reach a therapeutic space – defined as a 4 or below on the pain scale. Keep Track of Patient Bowel Movements [16:30] – This is important because narcotics are known to be constipating – they slow the stimulation of our gastrointestinal tract and our ability to have regular bowel movements. You want to get ahead of this problem as a caregiver. The patient should relieve themselves every one to two days for comfort purposes – it can turn into a crisis situation if they become constipated for an extended period of time. Stool softeners and laxatives should be included on the medication administration page of your Hospice comfort kit. Pain Management at the End of Life and Addiction [22:01] – There are many misconceptions about this topic and the lack of knowledge often leads to unnecessary suffering. Addiction often occurs in people who have a pre-disposition to it within their biochemistry or when a person abuses drugs recreationally to achieve a euphoric state – when there is no underlying pain to manage. At end of life, these should not be major concerns – especially because the medications should be controlled with the goal of keeping their pain at a 4 or below and assessing regularly. This person is going to have their end of life, and they're either going to have it being comfortable and having their pain managed – or suffering and having a lot of pain. Pain management is neither going to prevent the end of life or hasten the end of life – it's a question of them either being comfortable in this last phase of their life or being in pain and suffering in this last phase. Addiction is a medical condition that requires us to reserve judgment and lead with compassion. It is not a justifiable reason to withhold medication at end of life – keep the medicine locked away and control it to avoid issues. Our job is to be present, be loving, and to support this person at the end of their life – no matter what their past has been. Everyone deserves to be comfortable at end of life. Memorable Quotes: “The rule of thumb for medication and pain management is that on a pain scale of 1 to 10 – 1 being no pain and 10 being the most pain somebody can possibly be in – you want that pain to be kept at a 4 or below.” – Suzanne B. O'Brien RN “We know that end of life is really hard on everyone. Everyone in the family is touched by end of life and all people are probably having different experiences.” – Suzanne B. O'Brien RN “Pain management is not about completely eliminating pain. It is about controlling it well enough so that it is not causing every second of every day to be defined by suffering and a lack of quality of life.” – Suzanne B. O'Brien RN Resources: – GET THE FREE DEATH DOULA GUIDE HERE: HERE PLEASE Rate & Review the Podcast, leave a comment and share with your friends! xo Suzanne
Gabapentin has a wide variety of uses but the main indications are for focal seizures in adults and children and for postherpatic neuralgia in adults. There are many commonly used off label indications such as for neuropathic pain, fibromyalgia, and alcohol dependence. Max dosing for gabapentin is around 3600 mg/day. Although the exact mechanism of action is unknown, it is clear that it is similar in chemical structure to GABA. This is important because GABA is responsible for modulating excitatory neurotransmitter release. Gabapentin is poorly protein bound at less than 3% and not metabolized. When discontinuing longer term therapies, doses should be tapered down over at least 7 days. Some of the most common side effects are dizziness, fatigue, and weight gain. The serious side effects are depression, suicidal thoughts and behaviors, and withdrawal related seizures. Go to DrugCardsDaily.com for my episode show notes which will contain a drug summary, quiz, and a link to FREE drug card sheets. SUBSCRIBE on Spotify or Apple Podcasts or search for us on your favorite place to listen to podcasts. I will go over the Top 100-200 Drugs as well as throwing in some recently released drugs that peak my interest. Also, if you'd like to say hello, suggest a drug, or leave any constructive feedback on the show I'd really appreciate it! Leave a voice message at anchor.fm/drugcardsdaily or message us through twitter @drugcardsdaily --- Send in a voice message: https://anchor.fm/drugcardsdaily/message
In this episode I interview Attorney Michael Mosher who has 30 years of experience. Mr. Mosher has an extensive background in pharmacokinetics, the adverse reactions of various drugs as well as the proper administration of each psychotropic drug including anxiolytics (eg. Xanax, Ativan, Klonopin), hypnotics (Halcion, Dalmane, Restoril), stimulants (eg. Ritalin, dexedrine, Adderall), anticonvulsants (eg. Tegretol, Depakote, Neurontin), antidepressants (eg. all the SSRIs, Effexor and the tricyclic antidepressants), and neuroleptics, (eg. Zyprexa, Risperdal, Seroquil, Abilify). Mr. Mosher has also settled numerous cases against doctors and drug companies involving illnesses and damage due to addiction/dependence via the use of Xanax, Klonopin and other benzodiazepines as well as injuries resulting from SSRIs.
Pfizer's History of Crimes and Misdemeanors Richard Gale and Gary Null Progressive Radio Network, March 10, 2021 Whenever it is necessary to make an evaluation of the efficacy and safety of conventional drug-based medicine, it is imperative to include the rising rate of iatraogenic injuries and deaths – medical errors – that has become the third leading cause of death in the US after cardiovascular disease and cancer. The majority of these deaths are caused by FDA approved drugs' adverse effects and when patients are prescribed multiple medications in the absence of thorough clinical research to determine the safety of their synergistic effects. Consequently our health agencies' oversight and monitoring of drugs on the market is dismal and deadly. Among the top pharmaceutical companies whose drugs and products have most contributed to the nation’s iatrogenic epidemic is the $51 billion multinational behemoth Pfizer Inc, the world’s third most profitable drug maker. Pfizer is one of America’s oldest pharma firms, founded by Charles Pfizer and Charles Erhart in a Brooklyn red brick building in 1849. The chemical company began to boom in the 1880s after becoming the leading manufacturer of the chelating, flavoring and preservative agent citric acid. With its expertise in fermentation chemistry, Pfizer later became a leader in the production of penicillin and ascorbic acid (Vitamin C). Today its 300-plus drugs are commonplace in American doctors’ tool kits: Zoloft, Zantac, Viagra, Enbrel, Flagyl, Lipitor, and several antibiotics. It is also a major player in the generic drug market and is rapidly becoming a leading vaccine maker with its pneumococcus vaccine (Prevnar) and more recently with its controversial mRNA vaccine against the SARS-CoV2 virus. In the irrational panic to quickly get a vaccine against the SARS virus to market, its Covid-19 vaccine was the first to receive emergency use authorization Pfizer's legacy of lawsuits goes back to the late 1950s. According to the Corporate Research Project, it “has been at the center of controversies over its drug pricing for more than 50 years.” Back in 1958 it was charged by the Federal Trade Commission for price fixing and making false statements to dubiously acquire a patent for tetracycline. Two years later the Justice Department filed criminal antitrust charges against Pfizer’s board chairman and president John McKeen on the matter. Again in 1996, the drug company paid out $408 million to settle another lawsuit for price fixing and gouging pharmacies. In 2002, Pfizer was caught defrauding the federal Medicaid program for over-charging its flagship cholesterol drug Lipitor. Other similar charges include a $784 million settlement for underpaid rebates to Medicaid and $107 million fine for overcharging its epilepsy drug phenytoin sodium. The company has even stooped so low as to engage in bogus advertising. Shortly after the Second World War, Pfizer created snazzy ads for the Journal of the American Medical Association for its antibiotic line. The ads included named physicians endorsing its drugs. However, according to a Saturday Review investigation, the doctors turned out to be completely fictitious. As the company is positioned to earn $19 billon from its Covid-19 vaccine, at the same time it is legally battling against hundreds of lawsuits due to its popular heartburn drug, Zantac, being contaminated with the carcinogen N-nitrosodimethylamine (NDMA), an “extremely hazardous” toxin used in rocket fuel and industrial lubricants. Although the FDA erroneously claims that Zantac’s NDMA levels are low, they have still been measured to be between 3,000 and 26,000 times higher than the FDA’s safety cut-off point. Another adverse effect of NDMA is hepatotoxicity leading to liver fibrosis and scarring. According to the law firm Matthews and Associates, since “the history of Pfizer is rife with so much subterfuge and under-the-table dealing that the company will need all the help it can get to promote confidence in its hastily assembled Covid vaccine.” If the mainstream media were to honestly cover the NDMA trial underway and other Pfizer confrontations with the law, perhaps its vaccine would not be receiving such uncritical fanfare. There would be more scrutiny and warranted suspicion to question how Pfizer could have developed a truly safe and effective vaccine in such a short period of time. In our earlier reviews of the criminal records of Merck and Johnson and Johnson, we did not find evidence of the depths of demented ethical behavior solely to manipulate its market control as we do with Pfizer. In fact, Pfizer seemingly is in competition to outdo notorious hedge fund vulture capitalist and underworld strategies to bully governments in return for securing supplies of its Covid-19 vaccine. For example, Pfizer demanded that Argentina pay the company compensation for any civil lawsuits filed against it. The government compromised and ruled that Pfizer would only pay fines for any negligence on the company’s behalf with respect to supply and distribution. But that was not agreeable to the vaccine maker. Instead it then demanded that Argentina provide its sovereign assets –bank reserves, military bases and embassy buildings – as collateral to secure vaccine supplies. In Brazil, Pfizer’s aggressive and malignant efforts failed. It demanded that the Brazilian government turn over a guaranteed fund deposited in a foreign bank account and that the government would waive its sovereign assets abroad. Pfizer also demanded that it not be held legally liable for any injuries or deaths due to its vaccine. Correctly, President Bolsonaro called Pfizer’s demands “abuse” and rejected the deal. If this gives the impression that Pfizer is a serial predator on poorer foreign nations, Argentina and Brazil are only the most recent examples. In 1996, the company conducted illegal experimental trials with an unapproved experimental antibiotic, Trovan, on Nigerian children without parental knowledge or consent. The case was not raised in a US federal court until 2001 after thirty Nigerian families sued. After 100 children were given the drug as guinea pigs, “eleven children in the trial died, others suffered brain damage, were partly paralyzed or became deaf.” Nigerian medical experts ruled that Pfizer violated international law and the US federal case was eventually settled a decade later for an undisclosed amount. Pfizer’s dirty politics and mafia-like activity in the Nigeria scandal, reminding us of Monsanto’s sleazy schemes, goes beyond the dangers of an experimental antibiotic. Wikileaks made available State Department cables showing that Pfizer had hired spies to dig up dirt to frame a former Nigerian attorney general in order to get the lawsuit dropped. It also tried to shift the blame of the scandal on Doctors Without Borders by making a false claim that the non-profit charitable group was responsible for dispensing the antibiotic. Already in the US, thanks to Reagan’s Vaccine Injury Compensation Act, vaccine makers are off the hook for being held legally accountable for vaccine adverse effects. Now the company is demanding that other nations change their laws solely for Pfizer to secure maximum profits from its Covid vaccine. Pfizer’s actions are utterly parasitical. Nor should we forget that the development of its vaccine has largely been publicly funded. Its Covid vaccine partner Biontech received $445 million from the German government, and Pfizer has received almost $2 billion from US taxpayers as pre-payment for a vaccine. Pfizer’s leech-like behavior goes back even further. In 2003, after it appeared that Congress might pass a bill to permit cheaper prescription drugs in Canada for sale in the US, Pfizer attempted to change the rules of the game and demand Canadian pharmacies to order directly from Pfizer rather than wholesalers in order to dominate the market and interrupt the supply chain. Pfizer’s track record for fines and lawsuits for violation of its drug safety profiles and ethical marketing are equally damning. In 2009, it was fined $2.3 billion for what was then the largest healthcare felony settlement in US pharmaceutical history for illegally promoting its drugs, including its painkiller Bextra. $1.2 billion was just for the criminal fine; at the time, this was the largest ever imposed in the US for any issue. In 2011, it was found guilty of racketeering charges for illegally marketing its anticonvulsant drug Neurontin and paid $142 million. Three years later Pfizer was fined $430 million to settle criminal charges for bribing doctors to promote and prescribe the same drug. Nor should we ignore Pfizer’s dreadful environmental record: 1971 - Long time illegal dumping of a million gallons of industrial waste annually from its Groton plant into the Long Island Sound; 1991 - A $3.1 million fine for refusing to install pollution control equipment in its Delaware River plant 1994 – A $1.5 million fine for illegal dumping at a toxic waste site in Rhode Island 2003 – Paid a $700 million settlement for dumping PCBs in Anniston, Alabama. Now, we are facing the widespread distribution of Pfizer’s experimental mRNA Covid-19 vaccine wherein the trials to determine its level of safety and efficacy are still underway. It is still too early to make any determination of Pfizer having been engaged in any nefarious activities to get its vaccine rushed to the public. Impropriety and medical negligence so far lies on our government’s shoulders and our bought-off corporate media. Federal health agencies simply ignored their regulatory obligations and gave the vaccine a green light prematurely. Nevertheless, reports of injuries and deaths continue to mount and we will not have any sense of the full cost to human life and suffering from vaccine injuries for a while. In the meantime, China has suspended the mRNA vaccine after a flurry of deaths among Norwegian elderly. The Gibraltar Chronicle reported the deaths of 13 people within two days of receiving Pfizer’s vaccine and that number has risen to over 50 on the tiny island. Hundreds of vaccinated Israelis are still coming down with SARS-CoV2 infections after vaccination. The highly prestigious journal Science reported the growing concerns over the Pfizer vaccine’s polyethylene glycol nanoparticle and its relationship to the growing number of rare but serious allergic reactions and cases of anaphylaxis. And in a briefing document released by the CDC’s Vaccines and Related Biological Products Advisory Committee gave warning that the Pfizer vaccine trials give indication of unusual and unexpected antibody responses, cytokine storms and pathogenic priming that give rise to critical illness and death. Therefore there is no evidence whatsoever that Pfizer’s Covid-19 vaccine can scientifically and consensually be ruled as safe. But as we have observed from Pfizer’s litany of criminal activities above, safety and effectiveness of a drug or product has never been a priority in the company’s executive office. All told, these examples of Pfizer's culture of greed, deception, political maneuvering and mafia-like tactics has collectively injured countless people. Pfizer is a global corporation. Its drugs, and now its Covid-19 vaccine are marketed globally. To better understand Pfizer, the company should be perceived foremost as a cash cow for Wall Street. Its prime directive is selling drugs; its history of misdemeanors and crimes should indicate the company holds no integrity or medical ethics with a sincere commitment to prevent and treat disease. For firms such as Pfizer, injuries and deaths are the necessary collateral damage of getting poorly tested products on the market and as fast as possible. In our opinion, a black box warning should be slapped on the Pfizer logo. And should we trust such a company with the potential to vaccinate an enormous percent of the world population with an experimental vaccine?
People living with multiple sclerosis often experience chronic numbness, burning, tingling and pins-and-needles sensations. In a recent study, 70% of people with MS reported numbness and tingling, and 55% reported pain associated with relapses. MS neurologists explain typical symptoms for brain and spinal cord MS attacks compared to a pinched nerve in the back (like sciatica) or neuropathy. Lhermitte's sign (shocks down the spine when moving neck) and Uhthoff's phenomenon (numbness when overheated) are covered since frequently the first symptoms of multiple sclerosis. Options for relief from burning, tingling and pins-and-needles reviewed including medications such as Neurontin (gabapentin), Lyrica (pregabalin), Elavil (amitriptyline) and Cymbalta (duloxetine). Painful MS syndromes including trigeminal neuralgia, MS hug, and flexor and extensor spasms are reviewed with numerous treatment options. MS experts also share options to alleviate painful muscle cramps and spasms as well as musculoskeletal pain, such as low back pain. The podcast aims to provide awareness and options for relief so that people living with MS can better communicate with their doctors to improve their care. Barry Singer MD, Director of The MS Center for Innovations in Care, interviews: Mitzi Joi Williams MD, a MS neurologist and the founder and CEO of Joi Life Wellness Group Multiple Sclerosis Center. Dr. Williams completed her neurology residency (including serving as chief resident) and multiple sclerosis fellowship at Georgia Health Sciences University (formerly MCG) in Augusta, GA. She is the author of MS Made Simple: The Essential Guide to Understanding Your Multiple Sclerosis Diagnosis. Brandon Beaber MD, an MS neurologist at Kaiser Permanente in Los Angeles. He completed his neurology residency at Kaiser Permanente’s Los Angeles Medical Center (LAMC) and fellowship in multiple sclerosis and neuroimmunology at University of Southern California. He authored Resilience in the Face of Multiple Sclerosis and regularly posts educational videos for people living with MS on his YouTube channel. Visit mslivingwell.org for more information. Share your MS story on ICanWithMS.org
Gabapentin, commonly known as Neurontin, is a prescribed painkiller of its own drug class, Gabapentinoids. https://recoverypartnernetwork.com/drug/illicit/gabapentin-addiction
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TESTO DELL'ARTICOLO ➜http://www.bastabugie.it/it/articoli.php?id=6405LA PFIZER, LE FRODI SANITARIE E IL VACCINO CONTRO IL CORONAVIRUSI tempi per il vaccino anti-Covid sono stati estremamente accelerati... ma è giusto che sia la popolazione a fare da cavia? (VIDEO: Inventori di malattie, con una intervista all'ex vicepresidente del settore marketing della Pfizer)da WikipediaPfizer Inc. è un'azienda farmaceutica statunitense. È la più grande società del mondo operante nel settore della ricerca, della produzione e della commercializzazione di farmaci. [...]La Pfizer vanta la più grande organizzazione di ricerca e sviluppo dell'industria farmaceutica grazie alla sua divisione Pfizer Global Research and Development. Malgrado ciò gli investimenti nella ricerca sono stati ridotti, dai 10,5 miliardi di dollari del 2008 e ai 9,4 del 2010, mentre nel 2011 si è passati a 6,5-7 miliardi. La riduzione dei costi che Pfizer ha fatto a partire dal 2003 (anno dell'acquisizione di Pharmacia) è andata a danno dell'occupazione. Infatti, la multinazionale ha ridotto la propria forza lavoro di circa 40.000 unità in questi anni. I dipendenti della società, all'inizio del 2011, si sono ridotti a circa 110.600. [...]Accanto al settore farmaceutico, la Pfizer è inoltre presente nell'area veterinaria (Pfizer Animal Health). LA PIÙ GRANDE FRODE DELLA STORIANel 2009 Pfizer si è dichiarata colpevole della più grande frode nella storia della sanità degli Stati Uniti e ha ricevuto la più grande sanzione penale mai riscossa; la frode è consistita nella commercializzazione illegale di quattro dei suoi farmaci nei dieci anni precedenti, fra cui Bextra.Inoltre la Pfizer è responsabile di aver effettuato test per farmaci molto pericolosi sulle popolazioni nei Paesi in via di sviluppo, soprattutto in Africa e alcuni suoi funzionari sono stati sospettati di essere mandanti di omicidi ai danni di attivisti per i diritti civili. La Pfizer da oltre un decennio si è strategicamente impegnata in una serie di acquisizioni di aziende farmaceutiche al fine di conquistare quote sempre più significative del mercato farmaceutico mondiale. Acquisizioni che hanno comportato come effetti collaterali la massiccia perdita di posti di lavoro e di valore azionario. Anche in Italia la Pfizer ha dismesso centri di ricerca e diverse centinaia di lavoratori delle aziende acquisite. [...] Pfizer, il 9 novembre 2020, ha annunciato di aver trovato un vaccino per la malattia da COVID-19 che dimostra un'efficacia sul 90% dei casi testati, secondo le dichiarazioni della casa farmaceutica entro fine dell'anno saranno pronte oltre 50.000.000 di dosi, il che la renderebbe la prima casa farmaceutica ad aver trovato un vaccino per far fronte alla pandemia da COVID-19.Il vaccino è attualmente in fase di distribuzione in Inghilterra ed in Canada, è prossimo ad ottenere l'approvazione di Emea per l'utilizzo nell'unione europea. Lo stesso giorno dell'annuncio del vaccino alla stampa le azioni della società hanno registrato un balzo del 16% in Borsa. [...]VICENDE GIUDIZIARIESono diversi i casi di Disease-mongering cui la Pfizer è stata coinvolta negli anni. La Pfizer negli anni è stata oggetto di una serie di vicende giudiziarie negli USA a seguito di comportamenti illegali. In particolare dal 1999 al 2006 sono stati 6 i casi giudiziari in cui la Pfizer si è dovuta difendere da diverse tipi di accuse. Questi casi hanno comportato per la Pfizer un risarcimento in indennizzi pari ad un totale di 2.890.100.000 di $, di cui 715,4 milioni riguardano contratti del Governo Federale USA.Va detto però che Pfizer, a proposito delle multe pagate per gli usi off-label dei suoi farmaci, ha comunque ottenuto un vantaggio economico avendo venduto molte più confezioni dei suoi farmaci nelle indicazioni non approvate rispetto a quelle approvate, con un ampio margine di profitto rispetto alle multe pagate. Infatti, con il Neurontin, negli usi off-label, ha realizzato circa 2 miliardi di $; così come raccontato nel suo libro: Global Pharma (ediz. Rizzoli 2007) da Peter Rost, ex manager di Pfizer. [...]SPERIMENTAZIONE ILLEGALE IN NIGERIAUno dei casi più gravi riguarda la vicenda del farmaco trovafloxacina/alatrofloxacina che è stato ritirato dal mercato per gravi, imprevedibili e fatali effetti collaterali di tipo epatico (epatite fulminante); questa decisione in Europa è stata presa dal CPMP dell'Agenzia europea per i medicinali (EMEA) l'11 giugno 1999. Esso è oggi commercializzato, con forti limitazioni d'uso, solamente in Canada e negli USA dalla Pfizer Inc. con il nome commerciale di: Trovan. La Pfizer, detentrice del brevetto, a causa di una sperimentazione umana, fatta nel 1996 su dei bambini nigeriani ha determinando più di 200 tra decessi e gravi lesioni. Per questo la multinazionale ha dovuto difendersi legalmente, nel 2001, dalle accuse mosse dal governo Nigeriano di sperimentazione illegale con un trattamento crudele, inumano e degradante e sfruttamento dell'ignoranza dei genitori dei bambini morti. Nel 2009 la Pfizer raggiunge un accordo con le autorità governative federali nigeriane della regione di Kano per il pagamento ai familiari delle vittime di una somma pari a 45 milioni di $ e 30 milioni di $ da devolvere in iniziative sanitarie; fermo restando una di una richiesta risarcimento di 6 mil. di $ pendente presso la corte di giustizia nazionale nigeriana. Il 30 luglio 2009, la Pfizer dichiara spontaneamente di aver accettato di pagare 75 milioni di $ che il governo nigeriano ha chiesto per chiudere le accuse penali e civili per il caso Trovan. Nel luglio 2010 la Pfizer contesta una decisione che riguarda l'esclusione della stessa, con il trasferimento a Kano in Nigeria, dell'esecuzione del test del DNA per il riconoscimento dei parenti delle vittime da indennizzare.Nota di BastaBugie: Paolo Gulisano nell'articolo seguente dal titolo "Vaccino, sarà la popolazione a fare da cavia" esprime dubbi sui tempi per la realizzazione del vaccino anti-Covid che sono stati estremamente accelerati. Questo vaccino sarà sicuro? Non si conoscono gli effetti collaterali di lungo periodo. Sarà la popolazione vaccinata a fare da cavia. Per questo non può e non deve essere obbligatorio.Ecco l'articolo completo pubblicato su La Nuova Bussola Quotidiana l'11 dicembre 2020:Se la prima fase della pandemia da Covid è stata dominata dalla virologia, quella seria che cercava di capire il nuovo Coronavirus arrivato dalla Cina, le sue caratteristiche, le sue modalità di azione, la nuova fase che stiamo attraversando, in cui quella che è stata definita "seconda ondata" ha già iniziato, a partire dagli ultimi giorni di novembre, la fase discendente per numero di positivi, di ricoverati e di deceduti, sarà la fase della vaccinologia. Ovvero dibattiti, discussioni, scontri e aspre polemiche in merito alle vaccinazioni anti Covid.Dopo aver presentato il Piano organizzativo nazionale, entriamo nel merito di questi vaccini che sono destinati, tra circa un mese, ad essere utilizzati nel nostro Paese. Occorrerà attendere l'autorizzazione ufficiale da parte di AIFA, l'Agenzia Italiana del Farmaco, che farà seguito a quella dell'EMA (European Medicines Agency), l'analogo ente di livello europeo. I media, così come i politici e buona parte dell'opinione pubblica, danno l'esito già per scontato. Eppure questi enti devono ancora completare l'esame dei dossier presentati dalle ditte produttrici, che devono comprendere prove precliniche di laboratorio e prove cliniche su esseri umani, di fase 1 (prove di sicurezza e tollerabilità di varie dosi su volontari sani), fase 2 e 3, cioè prove su gruppi di volontari in cui si confronta efficacia ed effetti avversi in gruppi trattati o col farmaco o col placebo.Si tratta di studi che normalmente e giustamente richiedono molto tempo. Per mettere a punto un vaccino occorrono mediamente cinque-sei anni. E non sempre l'esito di questi tentativi è favorevole. Nel caso della famiglia dei Coronavirus, in sessant'anni non si è mai riusciti a mettere a punto un vaccino. Nemmeno per il Coronavirus della Sars del 2002-2003. Si arrivò molto vicini - per quattro volte - al completamento della sperimentazione di un vaccino, ma alla fine nessuno venne mai messo in produzione a causa degli effetti collaterali.A fronte dell'attesa entusiastica di molti per il vaccino, si stanno contemporaneamente diffondendo molte preoccupazioni relative agli effetti collaterali possibili, obiezioni legittime e ragionevoli davanti alle quali sta montando sui media e sui social un odio rabbioso, un'intolleranza che non ammette repliche. Eppure la questione della sicurezza di un vaccino, come di qualunque farmaco, andrebbe approcciata con maggiore attenzione, equilibrio e razionalità. Non si capisce perché l'uso di determinati farmaci, peraltro usati da decenni come la Clorochina, sia stato contrastato da un muro di diffidenza, mentre questi vaccini dovrebbero essere accolti come indubitabilmente sicuri. Gioverà rammentare che per i farmaci normali sono richieste anche prove di farmacocinetica, vale a dire dimostrazioni di dove si accumulano nel corpo e di quanto tempo vi rimangono prima di essere eliminati; i vaccini invece sono esentati dalla presentazione di queste prove, per cui non si conosce il destino del vaccino nel corpo in cui è stato iniettato.Secondo il professor Paolo Bellavite, già professore di Patologia Generale presso l'Università di Verona, ematologo ed esperto di Statistica Sanitaria, per i vaccini anti-Covid i tempi di realizzazione sono stati straordinariamente accorciati rispetto alle normali fasi di studio di un vaccino. Finora si conoscono alcuni risultati di fase 1, pochi di fase 2 e nessuno di fase 3 se non alcuni risultati parziali di uno fatto in Brasile. E per quanto riguarda le reazioni avverse ai vaccini, conosciamo solo quelle rilevate in piccoli gruppi e insorgenti nel breve periodo, in genere entro una settimana dall'inoculo.
Julie Current is a survivor. She had a rough childhood and as an adult she survived physical abuse that led to multiple disabilities like PTSD, chronic pain, and epilepsy. With kratom, kava, and cannabis as tools, she’s coming up on two years sober on October 28. This is Julie Current and this is her kratom […] The post 36. Surviving Abuse and Addiction with Julie Current first appeared on Kratom Science.
Not Just a Chiropractor for Stamford, Darien, Norwalk and New Canaan
Neuropathy@CoreHealth551 Post Road Darien CT 06820Pregabalin (Lyrica) and gabapentin (Neurontin) are two medications used for the treatment of neuropathic pain. These medications are called antiepileptics and were originally used to treat seizures, but are also commonly used for neuropathic conditions such as post-herpetic neuralgia, diabetic peripheral neuropathy, and fibromyalgia. They help by calming pain signals in the brain. Neurontin takes longer to begin working, and does not work for as long as Lyrica; therefore, it must be taken more frequently. Side effects are similar between the two (mainly dizziness and drowsiness). Neurontin is more likely to cause coordination issues and vision or eye movement issues, while Lyrica is more likely to cause swelling, weight gain, and tremors. Lyrica is considered a controlled substance, while Neurontin is not. Finally, Lyrica is significantly more costly than Neurontin.Based on all you've learned, you think that Lyrica might be a better choice for you since it has been shown to be more effective for fibromyalgia. It also doesn't need to be taken as often, and you commonly forget to take your pills. You have very good insurance, so are not worried about cost. You are also concerned about the side effects but plan to keep a close eye on these with your doctor. Neuropathy can be helped. Neuropathy@CoreHealth has been making an impact on the quality of people suffering from peripheral neuropathy for many years. Would you like more information? Call 203-656-3636.
Today's episode features another toxic drug of the week that we all need to be aware of and avoid. Rather than falling into the over-medicated cycle our society has made the norm, I encourage you to do some research and critical thinking when it comes to the drugs you put in your body, and I'm here to help with that. You can find show notes and more information by clicking here: http://thedigestiondoctor.com/123
Access to MS symptom self-management care is extremely limited. That's why my guest, Dr. Anna Kratz, and her colleagues created My MS Toolkit -- a web-based, self-guided symptom self-care program designed especially for people with MS. (And it's FREE!) We're talking with Dr. Kratz about how My MS Toolkit was developed and what makes it such a powerful online tool for people living with MS. We're also talking about the latest petitions filed with the Supreme Court in the battle over the Affordable Care Act (and why this is so vitally important to people affected by MS!). If you're using gabapentin (Neurontin) to manage MS pain, we'll tell you about the warning that was just issued by the FDA. Yet another study gives us yet another reason to start disease-modifying therapy as soon as possible. And we'll explain why collecting real-world data about MS is so important, and what a team of MS experts is recommending to improve the process of real-world data collection and analysis. We have a lot to talk about! Are you ready for RealTalk MS??! ___________ Where I'll Be in January :27 National MS Society Joins 23 Other Patient Organizations in Requesting Supreme Court Expedites Its Review of the ACA 3:00 FDA Issues Warning About Gabapentinoids 6:51 Disease-Modifying Therapy Use Has Changed the 'Natural History' of Relapsing-Remitting MS 7:57 Paper Explores How Real-World Data Can Be Better Leveraged to Speed Solutions to People Living with MS 9:34 My Interview with Dr. Anna Kratz 15:04 Share This Episode 36:00 Download the RealTalk MS App 36:29 ___________ SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: http://realtalkms.com/123 ___________ ADD YOUR VOICE TO THE CONVERSATION I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: jon@realtalkms.comPhone: (310) 526-2283 ___________ LINKS If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the RealTalk MS app or at www.RealTalkMS.com My MS Toolkit FDA Warns About Serious Breathing Problems when Gabapentin and Pregabalin Are Used With CNS Depressants or By Patients with Lung Problems STUDY: Outcomes in a Modern Cohort of Treated Multiple Sclerosis Patients Followed from Diagnosis Up to 15 Years Leveraging Real-World Data to Investigate Multiple Sclerosis Disease Behavior, Prognosis, and Treatment Download the RealTalk MS App for iOS Download the RealTalk MS App for Android Give RealTalk MS a Rating & Review ___________ Follow RealTalk MS on Twitter, @RealTalkMS_jon, and subscribe to our newsletter at our website, RealTalkMS.com. RealTalk MS Episode 123 Hosted By: Jon Strum Guests: Dr. Anna Kratz Tags: MS, MultipleSclerosis, MSResearch, MSActivist, MSSociety, Gabapentinoids, ACA, RealTalkMS Privacy Policy
Listen to an audio podcast of the December 19, 2019 FDA Drug Safety Communication warning that serious breathing difficulties may occur in patients using seizure and nerve pain medicines gabapentin (Neurontin, Gralise, Horizant) and pregabalin (Lyrica, Lyrica CR) who have respiratory risk factors.
SHOW TOPICS: Mercury is a potent neurotoxin, Neurontin and Lyrica, Mumps, Gut bacteria, Heartburn Medications (Air Date 11.6.2017) Dr. Rashid A. Buttar hosts "Advanced Medicine" once a week with Robert Scott Bell on the Robert Scott Bell Show. Dealing with everyday health issues from the Advanced Medicine healthcare perspective, Dr. Buttar and Robert tackle the tough issues and empower you to achieve autonomy and maintain your health freedom.
The gabapentinoids are a class of drugs vaguely resembling the neurotransmitter GABA. Although they were developed to imitate GABA’s action, later research discovered they acted on a different target, the A2D subunit of calcium channels. Two gabapentinoids are approved by the FDA: gabapentin (Neurontin®) and pregabalin (Lyrica®). Gabapentin has been generic since 2004. It’s commonly used for seizures, nerve pain, alcoholism, drug addiction, itching, restless legs, sleep disorders, and anxiety. It has an unusually wide dose range: guidelines suggest using anywhere between 100 mg and 3600 mg daily. Most doctors (including me) use it at the low end, where it’s pretty subtle (read: doesn’t usually work). At the high end, it can cause sedation, confusion, dependence, and addiction. I haven’t had much luck finding patients a dose that works well but doesn’t have these side effects, which is why I don’t use gabapentin much. Pregabalin officially went generic last month, but isn’t available yet in generic form, so you’ll have to pay Pfizer $500 a month. On the face of things, pregabalin seems like another Big Pharma ploy to extend patents. The gabapentin patent was running out, so Pfizer synthesized a related molecule that did the same thing, hyped it up as the hot new thing, and charged 50x what gabapentin cost. This kind of thing is endemic in health care and should always be the default hypothesis. And a lot of scientists have analyzed pregabalin and said it’s definitely just doing the same thing gabapentin is. But some of my anxiety patients swear by pregabalin. They call it a miracle drug. They can’t stop talking about how great it is. I can’t use it too often, because of the price, but I’m really excited about the upcoming generic version coming out so I can use it more often.
The post Gabapentine (Neurontin) Nursing Pharmacology Considerations appeared first on NURSING.com.
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I've been there before. Panicking in the bathroom, wishing it wasn't true. It's a hard question to try to answer because nothing I say is going to make you feel magically better. If you're already sick then more than likely it's going to continue to some extent. But learning what works best for you and fighting it everyday could mean the difference between hospitalization and infection, or staying home. If you haven't done it already, I highly suggest you get a Doctor's appointment, the soonest available. Ask for medication and start taking it round the clock right away. If you haven't gotten sick yet, you could just have it on hand until it starts. For some people it's violent from the start. Keeping yourself out of a bad cycle of dehydration and vomiting and not eating is the overall goal. Medication to ask about: Zofran: (prescription) (ondansetron) Anti-emetic (it helps control the vomiting) Unisom: (Over the counter) (doxylamine) anti-histamine (helps control the nausea) Diclectin: (prescription) (Pyridoxine/doxylamine) which is unisom and B6 together in a time release capsule. Phenergan: (prescription) (Promethazine), (I.V., suppositories, pill) Reglan: (prescription) (Metoclopramide) dopamine-receptor antagonist. It can help with nausea and vomiting by helping with gastric emptying. It's often given to people with GERD. However, one adverse effect to watch out for is called tardive dyskinesia. It can also make you feel tired, restless and anxious. Gabapentin: (prescription) (Neurontin) anticonvulsant and analgesic, usually given to control seizure disorders or neurological pain. This is still being trialed and is not commonly prescribed. Adverse effects for pregnancy are unknown. Dealing with constipation as a side effect of medication, notably Zofran. You can ask your doctor for a stool softener to be proactive and try to prevent constipation from happening. You can also try milk of magnesia or another kind of magnesium pill or liquid. That can help in numerous ways, including getting some much needed magnesium. If you're already constipated, I would suggest doing more than that to try to get ahead of the problem. Glycerin suppositories (can be found in more drug stores in the U.S.) Enemas (like Fleets brand enema): It comes in a self contained package with saline. One time use. Willard water Saline warm water Magnesium oil: You can make it yourself. It's actually not an oil but a solution of equal parts magnesium chloride and filtered water. What would you tell someone with HG who just found out they were pregnant?
The post Gabapentin (Neurontin) appeared first on NURSING.com.
Today's guest, Dr. Tom Guttuso, is currently conducting a four-year clinical trial to test the efficacy of Gabapentin otherwise known as Neurontin, with refractory Hyperemesis Gravidarum. Initial results of the small pilot study were positive. Dr. Guttuso also talks about how drug trials work and the only thing that they're testing. There is a closed facebook group dedicated to talking about Gabapentin during pregnancy. Request to join if you'd like to interact with other women who have taken Gabapentin during their pregnancy or would like to. There are other Doctors in the U.S. who are willing to try Gabapentin before the study is complete, especially for severe Hyperemesis that was controlled with other drugs. The group often post studies that they find, like this one. The results look promising. I know many women can't wait until the study is complete to try to have another baby. Would you consider taking Gabapentin or will you have to wait to see the results in 4 years?
Today in FirstWord:
Today in FirstWord:
Today in FirstWord:
The gang is back and there is much drinking to do. Dane and Doc deal with a cat that got killed in front of Sam's house. Kansas cost too damn much. There is some Dane's world. Sam has a Myelogram adventure at Lafayette General. Call the comment line at (206) 309-7308. E-mail at insignificast@gmail.com. Thanks for listening.