Podcasts about Osteoarthritis

Traveling can be exciting. But it can also create anxiety and new challenges to everyday tasks. In this episode, we explore tips, tools and techniques to make traveling with arthritis less painful. *Visit the Live Yes! With Arthritis Podcast episode page to get show notes, additional resources and read the full transcript: https://arthr.org/LiveYes_Ep135 (https://arthr.org/LiveYes_Ep135) * We want to hear from you. Tell us what you think about the Live Yes! With Arthritis Podcast. Get started by emailing podcast@arthritis.org (podcast@arthritis.org). Special Guest: Matt Iseman.

Podcast Summary This episode of the Pain Exam Podcast, hosted by Dr. David Rosenblum, discusses an interesting article about Ketorolac injections for musculoskeletal conditions. The podcast covers: Ketorolac is an NSAID that provides analgesic and anti-inflammatory effects through inhibition of prostaglandin synthesis Multiple studies comparing Ketorolac injections to corticosteroids and hyaluronic acid for various conditions Research shows Ketorolac injections are equally effective as corticosteroids for subacromial conditions, adhesive capsulitis, carpal-metacarpal joint issues, and hip/knee osteoarthritis Ketorolac may be a safer alternative to steroids for certain patients, though it has its own contraindications for those with renal, gastrointestinal, or cardiovascular disease Dr. Rosenblum considers the potential of using Ketorolac injections directly at pain sites rather than intramuscularly Upcoming Courses and Conferences Ultrasound courses in New York and Costa Rica (check unwrappedpain.org) Private ultrasound sessions available Dr. Rosenblum will be speaking at Pain Week about ultrasound in pain practice and PRP Presenting at a primary care conference in London Teaching ultrasound at ISPN LAPSES conference in Chile (Dr. Rosenblum won't attend this year) Ketorolac Injections: An Effective Alternative for Musculoskeletal Pain Management Musculoskeletal conditions such as bursitis, adhesive capsulitis, and osteoarthritis affect millions and often require injectable therapies to reduce pain and inflammation. Traditionally, corticosteroid injections have been the mainstay treatment. However, concerns over side effects like tendon rupture, cartilage damage, and systemic hyperglycemia have prompted exploration of alternatives. A recent narrative review by Kiel et al. (2024) highlights ketorolac—a parenteral nonsteroidal anti-inflammatory drug (NSAID)—as a promising substitute for corticosteroids in musculoskeletal injections. Warning: OFF Label use of Ketorolac discussed. Please consult your physician. See full article  for details. Subacromial Ketorolac Injections for Shoulder Pain Subacromial bursitis and impingement syndrome are common causes of shoulder pain and disability. Several randomized controlled trials have shown that subacromial ketorolac injections provide pain relief and functional improvement comparable to corticosteroids: Goyal et al. demonstrated significant reductions in pain scores after subacromial injection of 60 mg ketorolac versus 40 mg methylprednisolone, with no difference in outcomes between groups. Taheri et al. found similar short-term pain relief at 1 and 3 months with either ketorolac or corticosteroid subacromial injections. Kim et al. reported equivalent clinical improvement in rotator cuff syndrome patients receiving ketorolac or triamcinolone injections. Min et al. noted ketorolac led to better forward flexion and patient satisfaction at 4 weeks compared to corticosteroids. These studies support ketorolac as an effective agent for subacromial injection, offering an alternative for patients where corticosteroid use is limited. Intra-articular Ketorolac Injections for Adhesive Capsulitis and Osteoarthritis Adhesive capsulitis (frozen shoulder) and osteoarthritis of the hip, knee, and carpometacarpal joint are often treated with intra-articular corticosteroids. Ketorolac injections have shown comparable efficacy in these conditions: Akhtar et al. found intra-articular ketorolac significantly reduced shoulder pain at 4 weeks in adhesive capsulitis compared to hyaluronic acid. Ahn et al. reported similar pain relief between intra-articular ketorolac and corticosteroid injections in adhesive capsulitis, with ketorolac providing superior shoulder mobility at 3 and 6 months. Koh et al. showed that adding ketorolac to hyaluronic acid injections in carpometacarpal osteoarthritis resulted in faster onset of pain relief compared to hyaluronic acid alone. Park et al. observed equivalent functional improvements with intra-articular ketorolac or corticosteroids in hip osteoarthritis. Jurgensmeier et al. demonstrated similar symptom improvement at 1 and 3 months post-injection for ketorolac and triamcinolone in hip and knee osteoarthritis. Xu et al. and Bellamy et al. confirmed ketorolac's comparable pain relief and functional benefits to corticosteroids for knee osteoarthritis, with ketorolac being more cost-effective. Lee et al. noted quicker pain reduction with intra-articular ketorolac combined with hyaluronic acid versus hyaluronic acid alone in knee osteoarthritis. aSafety and Pharmacologic Considerations Ketorolac's anti-inflammatory action stems from cyclooxygenase inhibition, reducing prostaglandin synthesis. Its half-life is approximately 5.2–5.6 hours, and it is metabolized in the liver. Unlike corticosteroids, ketorolac avoids systemic hyperglycemia and cartilage damage risks. Animal and in vitro studies suggest ketorolac may protect cartilage by inhibiting inflammatory cytokines. While gastrointestinal, renal, and cardiovascular risks associated with NSAIDs remain considerations, localized intra-articular and subacromial ketorolac injections may limit systemic exposure and adverse effects. Mild, transient post-injection pain has been reported but resolves without intervention. Conclusion Ketorolac injections, administered intra-articularly or subacromially, are a safe, effective, and economical alternative to corticosteroids for managing common musculoskeletal conditions. Their comparable efficacy in reducing pain and improving function, combined with a more favorable side effect profile, makes ketorolac an appealing option for clinicians and patients alike. Further research is warranted to fully elucidate long-term safety and optimal dosing strategies. FAQS Ketorolac Injections for Musculoskeletal Conditions: Frequently Asked Questions Musculoskeletal pain from conditions like bursitis, adhesive capsulitis, and osteoarthritis often requires injectable treatments. Ketorolac, a nonsteroidal anti-inflammatory drug (NSAID), is emerging as a promising alternative to corticosteroids. Below are common questions and answers based on a recent narrative review by Kiel et al. (2024). 1. What is ketorolac and how does it work? Ketorolac is a parenteral NSAID that reduces pain and inflammation by inhibiting cyclooxygenase enzymes, which decreases prostaglandin synthesis. It can be administered orally, intramuscularly, intravenously, or by injection directly into joints or around bursae. 2. How effective is ketorolac for musculoskeletal conditions? Studies show ketorolac injections provide significant pain relief and functional improvement comparable to corticosteroids in conditions like: Subacromial bursitis and shoulder impingement (subacromial injections) Adhesive capsulitis (frozen shoulder) (intra-articular injections) Osteoarthritis of the hip, knee, and thumb carpometacarpal joint (intra-articular injections) 3. What evidence supports subacromial ketorolac injections? Randomized controlled trials found: Goyal et al. and Taheri et al. reported similar pain reduction and functional outcomes between ketorolac and corticosteroids for subacromial injections. Kim et al. and Min et al. observed comparable or better patient satisfaction and shoulder mobility with ketorolac versus corticosteroids. 4. How does intra-articular ketorolac compare to corticosteroids for adhesive capsulitis? Akhtar et al. showed ketorolac reduced shoulder pain more than hyaluronic acid. Ahn et al. found ketorolac and corticosteroids equally effective for pain relief, with ketorolac providing better shoulder mobility at 3 and 6 months. 5. What about ketorolac for osteoarthritis? Ketorolac combined with hyaluronic acid provided faster pain relief than hyaluronic acid alone in thumb carpometacarpal joint osteoarthritis (Koh et al.). Intra-articular ketorolac had similar efficacy to corticosteroids in hip (Park et al., Jurgensmeier et al.) and knee osteoarthritis (Bellamy et al., Xu et al.). Ketorolac injections were more cost-effective compared to corticosteroids (Bellamy et al.). 6. Are ketorolac injections safe? Ketorolac's side effects are similar to other NSAIDs, mainly involving gastrointestinal, renal, and cardiovascular risks. However, localized intra-articular and subacromial injections may reduce systemic exposure. Animal studies suggest ketorolac does not harm cartilage and may protect against inflammatory damage. Mild, transient local pain post-injection is possible but usually resolves without treatment. 7. What are the limitations of ketorolac use? Ketorolac is not suitable for patients with: Renal impairment Gastrointestinal ulcers or bleeding risk Cardiovascular disease or hypertension NSAID hypersensitivity, especially in asthma or chronic urticaria patients Clinicians should assess individual risks before choosing ketorolac injections. 8. How does ketorolac's pharmacokinetics affect its use? Ketorolac has a plasma half-life of about 5.2 to 5.6 hours and is metabolized in the liver. Pharmacokinetics for subcutaneous or intra-articular administration are less defined but systemic absorption occurs. Its relatively short half-life supports repeated dosing if needed. 9. Why consider ketorolac over corticosteroids? Ketorolac avoids corticosteroid-associated risks such as tendon rupture, cartilage damage, and steroid-induced hyperglycemia. It is also more cost-effective, making it a favorable option for patients and healthcare systems. 10. What further research is needed? More large-scale, long-term studies are needed to fully understand ketorolac's intra-articular effects, optimal dosing, and safety profile compared to corticosteroids and other treatments. Summary: Ketorolac injections, whether intra-articular or subacromial, offer a safe, effective, and economical alternative to corticosteroids for managing various musculoskeletal conditions. This makes ketorolac an important option in pain management and inflammation control.     Reference: Kiel J, Applewhite AI, Bertasi TGO, Bertasi RAO, Seemann LL, Costa LMC, Helmi H, Pujalte GGA. Ketorolac Injections for Musculoskeletal Conditions: A Narrative Review. Clinical Medicine & Research. 2024;22(1):19-27. DOI: https://doi.org/10.3121/cmr.2024.1847 Disclaimer: This Podcast, website and any content from NRAP Academy (PMRexam.com) otherwise known as Qbazaar.com, LLC is  for general informational purposes only and does not constitute the practice of medicine, nursing or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast or materials linked from this podcast is at the user's own risk. Professionals should conduct their own fact finding, research, and due diligence to come to their own conclusions for treating patients. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professionals for any such conditions.    

Podcast Summary This episode of the Pain Exam Podcast, hosted by Dr. David Rosenblum, discusses an interesting article about Ketorolac injections for musculoskeletal conditions. The podcast covers: Ketorolac is an NSAID that provides analgesic and anti-inflammatory effects through inhibition of prostaglandin synthesis Multiple studies comparing Ketorolac injections to corticosteroids and hyaluronic acid for various conditions Research shows Ketorolac injections are equally effective as corticosteroids for subacromial conditions, adhesive capsulitis, carpal-metacarpal joint issues, and hip/knee osteoarthritis Ketorolac may be a safer alternative to steroids for certain patients, though it has its own contraindications for those with renal, gastrointestinal, or cardiovascular disease Dr. Rosenblum considers the potential of using Ketorolac injections directly at pain sites rather than intramuscularly Upcoming Courses and Conferences Ultrasound courses in New York and Costa Rica (check unwrappedpain.org) Private ultrasound sessions available Dr. Rosenblum will be speaking at Pain Week about ultrasound in pain practice and PRP Presenting at a primary care conference in London Teaching ultrasound at ISPN LAPS  conference in Chile (Dr. Rosenblum won't attend this year) Ketorolac Injections: An Effective Alternative for Musculoskeletal Pain Management Musculoskeletal conditions such as bursitis, adhesive capsulitis, and osteoarthritis affect millions and often require injectable therapies to reduce pain and inflammation. Traditionally, corticosteroid injections have been the mainstay treatment. However, concerns over side effects like tendon rupture, cartilage damage, and systemic hyperglycemia have prompted exploration of alternatives. A recent narrative review by Kiel et al. (2024) highlights ketorolac—a parenteral nonsteroidal anti-inflammatory drug (NSAID)—as a promising substitute for corticosteroids in musculoskeletal injections. Warning: OFF Label use of Ketorolac discussed. Please consult your physician. See full article  for details. Subacromial Ketorolac Injections for Shoulder Pain Subacromial bursitis and impingement syndrome are common causes of shoulder pain and disability. Several randomized controlled trials have shown that subacromial ketorolac injections provide pain relief and functional improvement comparable to corticosteroids: Goyal et al. demonstrated significant reductions in pain scores after subacromial injection of 60 mg ketorolac versus 40 mg methylprednisolone, with no difference in outcomes between groups. Taheri et al. found similar short-term pain relief at 1 and 3 months with either ketorolac or corticosteroid subacromial injections. Kim et al. reported equivalent clinical improvement in rotator cuff syndrome patients receiving ketorolac or triamcinolone injections. Min et al. noted ketorolac led to better forward flexion and patient satisfaction at 4 weeks compared to corticosteroids. These studies support ketorolac as an effective agent for subacromial injection, offering an alternative for patients where corticosteroid use is limited. Intra-articular Ketorolac Injections for Adhesive Capsulitis and Osteoarthritis Adhesive capsulitis (frozen shoulder) and osteoarthritis of the hip, knee, and carpometacarpal joint are often treated with intra-articular corticosteroids. Ketorolac injections have shown comparable efficacy in these conditions: Akhtar et al. found intra-articular ketorolac significantly reduced shoulder pain at 4 weeks in adhesive capsulitis compared to hyaluronic acid. Ahn et al. reported similar pain relief between intra-articular ketorolac and corticosteroid injections in adhesive capsulitis, with ketorolac providing superior shoulder mobility at 3 and 6 months. Koh et al. showed that adding ketorolac to hyaluronic acid injections in carpometacarpal osteoarthritis resulted in faster onset of pain relief compared to hyaluronic acid alone. Park et al. observed equivalent functional improvements with intra-articular ketorolac or corticosteroids in hip osteoarthritis. Jurgensmeier et al. demonstrated similar symptom improvement at 1 and 3 months post-injection for ketorolac and triamcinolone in hip and knee osteoarthritis. Xu et al. and Bellamy et al. confirmed ketorolac's comparable pain relief and functional benefits to corticosteroids for knee osteoarthritis, with ketorolac being more cost-effective. Lee et al. noted quicker pain reduction with intra-articular ketorolac combined with hyaluronic acid versus hyaluronic acid alone in knee osteoarthritis. aSafety and Pharmacologic Considerations Ketorolac's anti-inflammatory action stems from cyclooxygenase inhibition, reducing prostaglandin synthesis. Its half-life is approximately 5.2–5.6 hours, and it is metabolized in the liver. Unlike corticosteroids, ketorolac avoids systemic hyperglycemia and cartilage damage risks. Animal and in vitro studies suggest ketorolac may protect cartilage by inhibiting inflammatory cytokines. While gastrointestinal, renal, and cardiovascular risks associated with NSAIDs remain considerations, localized intra-articular and subacromial ketorolac injections may limit systemic exposure and adverse effects. Mild, transient post-injection pain has been reported but resolves without intervention. Conclusion Ketorolac injections, administered intra-articularly or subacromially, are a safe, effective, and economical alternative to corticosteroids for managing common musculoskeletal conditions. Their comparable efficacy in reducing pain and improving function, combined with a more favorable side effect profile, makes ketorolac an appealing option for clinicians and patients alike. Further research is warranted to fully elucidate long-term safety and optimal dosing strategies. FAQS Ketorolac Injections for Musculoskeletal Conditions: Frequently Asked Questions Musculoskeletal pain from conditions like bursitis, adhesive capsulitis, and osteoarthritis often requires injectable treatments. Ketorolac, a nonsteroidal anti-inflammatory drug (NSAID), is emerging as a promising alternative to corticosteroids. Below are common questions and answers based on a recent narrative review by Kiel et al. (2024). 1. What is ketorolac and how does it work? Ketorolac is a parenteral NSAID that reduces pain and inflammation by inhibiting cyclooxygenase enzymes, which decreases prostaglandin synthesis. It can be administered orally, intramuscularly, intravenously, or by injection directly into joints or around bursae. 2. How effective is ketorolac for musculoskeletal conditions? Studies show ketorolac injections provide significant pain relief and functional improvement comparable to corticosteroids in conditions like: Subacromial bursitis and shoulder impingement (subacromial injections) Adhesive capsulitis (frozen shoulder) (intra-articular injections) Osteoarthritis of the hip, knee, and thumb carpometacarpal joint (intra-articular injections) 3. What evidence supports subacromial ketorolac injections? Randomized controlled trials found: Goyal et al. and Taheri et al. reported similar pain reduction and functional outcomes between ketorolac and corticosteroids for subacromial injections. Kim et al. and Min et al. observed comparable or better patient satisfaction and shoulder mobility with ketorolac versus corticosteroids. 4. How does intra-articular ketorolac compare to corticosteroids for adhesive capsulitis? Akhtar et al. showed ketorolac reduced shoulder pain more than hyaluronic acid. Ahn et al. found ketorolac and corticosteroids equally effective for pain relief, with ketorolac providing better shoulder mobility at 3 and 6 months. 5. What about ketorolac for osteoarthritis? Ketorolac combined with hyaluronic acid provided faster pain relief than hyaluronic acid alone in thumb carpometacarpal joint osteoarthritis (Koh et al.). Intra-articular ketorolac had similar efficacy to corticosteroids in hip (Park et al., Jurgensmeier et al.) and knee osteoarthritis (Bellamy et al., Xu et al.). Ketorolac injections were more cost-effective compared to corticosteroids (Bellamy et al.). 6. Are ketorolac injections safe? Ketorolac's side effects are similar to other NSAIDs, mainly involving gastrointestinal, renal, and cardiovascular risks. However, localized intra-articular and subacromial injections may reduce systemic exposure. Animal studies suggest ketorolac does not harm cartilage and may protect against inflammatory damage. Mild, transient local pain post-injection is possible but usually resolves without treatment. 7. What are the limitations of ketorolac use? Ketorolac is not suitable for patients with: Renal impairment Gastrointestinal ulcers or bleeding risk Cardiovascular disease or hypertension NSAID hypersensitivity, especially in asthma or chronic urticaria patients Clinicians should assess individual risks before choosing ketorolac injections. 8. How does ketorolac's pharmacokinetics affect its use? Ketorolac has a plasma half-life of about 5.2 to 5.6 hours and is metabolized in the liver. Pharmacokinetics for subcutaneous or intra-articular administration are less defined but systemic absorption occurs. Its relatively short half-life supports repeated dosing if needed. 9. Why consider ketorolac over corticosteroids? Ketorolac avoids corticosteroid-associated risks such as tendon rupture, cartilage damage, and steroid-induced hyperglycemia. It is also more cost-effective, making it a favorable option for patients and healthcare systems. 10. What further research is needed? More large-scale, long-term studies are needed to fully understand ketorolac's intra-articular effects, optimal dosing, and safety profile compared to corticosteroids and other treatments. Summary: Ketorolac injections, whether intra-articular or subacromial, offer a safe, effective, and economical alternative to corticosteroids for managing various musculoskeletal conditions. This makes ketorolac an important option in pain management and inflammation control.     Reference: Kiel J, Applewhite AI, Bertasi TGO, Bertasi RAO, Seemann LL, Costa LMC, Helmi H, Pujalte GGA. Ketorolac Injections for Musculoskeletal Conditions: A Narrative Review. Clinical Medicine & Research. 2024;22(1):19-27. DOI: https://doi.org/10.3121/cmr.2024.1847 Disclaimer: This Podcast, website and any content from NRAP Academy (PMRexam.com) otherwise known as Qbazaar.com, LLC is  for general informational purposes only and does not constitute the practice of medicine, nursing or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast or materials linked from this podcast is at the user's own risk. Professionals should conduct their own fact finding, research, and due diligence to come to their own conclusions for treating patients. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professionals for any such conditions.  

Podcast Summary This episode of the Pain Exam Podcast, hosted by Dr. David Rosenblum, discusses an interesting article about Ketorolac injections for musculoskeletal conditions. The podcast covers: Ketorolac is an NSAID that provides analgesic and anti-inflammatory effects through inhibition of prostaglandin synthesis Multiple studies comparing Ketorolac injections to corticosteroids and hyaluronic acid for various conditions Research shows Ketorolac injections are equally effective as corticosteroids for subacromial conditions, adhesive capsulitis, carpal-metacarpal joint issues, and hip/knee osteoarthritis Ketorolac may be a safer alternative to steroids for certain patients, though it has its own contraindications for those with renal, gastrointestinal, or cardiovascular disease Dr. Rosenblum considers the potential of using Ketorolac injections directly at pain sites rather than intramuscularly Upcoming Courses and Conferences Ultrasound courses in New York and Costa Rica (check unwrappedpain.org) Private ultrasound sessions available Dr. Rosenblum will be speaking at Pain Week about ultrasound in pain practice and PRP Presenting at a primary care conference in London Teaching ultrasound at ISPN LAPSES conference in Chile (Dr. Rosenblum won't attend this year) Ketorolac Injections: An Effective Alternative for Musculoskeletal Pain Management Musculoskeletal conditions such as bursitis, adhesive capsulitis, and osteoarthritis affect millions and often require injectable therapies to reduce pain and inflammation. Traditionally, corticosteroid injections have been the mainstay treatment. However, concerns over side effects like tendon rupture, cartilage damage, and systemic hyperglycemia have prompted exploration of alternatives. A recent narrative review by Kiel et al. (2024) highlights ketorolac—a parenteral nonsteroidal anti-inflammatory drug (NSAID)—as a promising substitute for corticosteroids in musculoskeletal injections. Warning: OFF Label use of Ketorolac discussed. Please consult your physician. See full article  for details. Subacromial Ketorolac Injections for Shoulder Pain Subacromial bursitis and impingement syndrome are common causes of shoulder pain and disability. Several randomized controlled trials have shown that subacromial ketorolac injections provide pain relief and functional improvement comparable to corticosteroids: Goyal et al. demonstrated significant reductions in pain scores after subacromial injection of 60 mg ketorolac versus 40 mg methylprednisolone, with no difference in outcomes between groups. Taheri et al. found similar short-term pain relief at 1 and 3 months with either ketorolac or corticosteroid subacromial injections. Kim et al. reported equivalent clinical improvement in rotator cuff syndrome patients receiving ketorolac or triamcinolone injections. Min et al. noted ketorolac led to better forward flexion and patient satisfaction at 4 weeks compared to corticosteroids. These studies support ketorolac as an effective agent for subacromial injection, offering an alternative for patients where corticosteroid use is limited. Intra-articular Ketorolac Injections for Adhesive Capsulitis and Osteoarthritis Adhesive capsulitis (frozen shoulder) and osteoarthritis of the hip, knee, and carpometacarpal joint are often treated with intra-articular corticosteroids. Ketorolac injections have shown comparable efficacy in these conditions: Akhtar et al. found intra-articular ketorolac significantly reduced shoulder pain at 4 weeks in adhesive capsulitis compared to hyaluronic acid. Ahn et al. reported similar pain relief between intra-articular ketorolac and corticosteroid injections in adhesive capsulitis, with ketorolac providing superior shoulder mobility at 3 and 6 months. Koh et al. showed that adding ketorolac to hyaluronic acid injections in carpometacarpal osteoarthritis resulted in faster onset of pain relief compared to hyaluronic acid alone. Park et al. observed equivalent functional improvements with intra-articular ketorolac or corticosteroids in hip osteoarthritis. Jurgensmeier et al. demonstrated similar symptom improvement at 1 and 3 months post-injection for ketorolac and triamcinolone in hip and knee osteoarthritis. Xu et al. and Bellamy et al. confirmed ketorolac's comparable pain relief and functional benefits to corticosteroids for knee osteoarthritis, with ketorolac being more cost-effective. Lee et al. noted quicker pain reduction with intra-articular ketorolac combined with hyaluronic acid versus hyaluronic acid alone in knee osteoarthritis. aSafety and Pharmacologic Considerations Ketorolac's anti-inflammatory action stems from cyclooxygenase inhibition, reducing prostaglandin synthesis. Its half-life is approximately 5.2–5.6 hours, and it is metabolized in the liver. Unlike corticosteroids, ketorolac avoids systemic hyperglycemia and cartilage damage risks. Animal and in vitro studies suggest ketorolac may protect cartilage by inhibiting inflammatory cytokines. While gastrointestinal, renal, and cardiovascular risks associated with NSAIDs remain considerations, localized intra-articular and subacromial ketorolac injections may limit systemic exposure and adverse effects. Mild, transient post-injection pain has been reported but resolves without intervention. Conclusion Ketorolac injections, administered intra-articularly or subacromially, are a safe, effective, and economical alternative to corticosteroids for managing common musculoskeletal conditions. Their comparable efficacy in reducing pain and improving function, combined with a more favorable side effect profile, makes ketorolac an appealing option for clinicians and patients alike. Further research is warranted to fully elucidate long-term safety and optimal dosing strategies. FAQS Ketorolac Injections for Musculoskeletal Conditions: Frequently Asked Questions Musculoskeletal pain from conditions like bursitis, adhesive capsulitis, and osteoarthritis often requires injectable treatments. Ketorolac, a nonsteroidal anti-inflammatory drug (NSAID), is emerging as a promising alternative to corticosteroids. Below are common questions and answers based on a recent narrative review by Kiel et al. (2024). 1. What is ketorolac and how does it work? Ketorolac is a parenteral NSAID that reduces pain and inflammation by inhibiting cyclooxygenase enzymes, which decreases prostaglandin synthesis. It can be administered orally, intramuscularly, intravenously, or by injection directly into joints or around bursae. 2. How effective is ketorolac for musculoskeletal conditions? Studies show ketorolac injections provide significant pain relief and functional improvement comparable to corticosteroids in conditions like: Subacromial bursitis and shoulder impingement (subacromial injections) Adhesive capsulitis (frozen shoulder) (intra-articular injections) Osteoarthritis of the hip, knee, and thumb carpometacarpal joint (intra-articular injections) 3. What evidence supports subacromial ketorolac injections? Randomized controlled trials found: Goyal et al. and Taheri et al. reported similar pain reduction and functional outcomes between ketorolac and corticosteroids for subacromial injections. Kim et al. and Min et al. observed comparable or better patient satisfaction and shoulder mobility with ketorolac versus corticosteroids. 4. How does intra-articular ketorolac compare to corticosteroids for adhesive capsulitis? Akhtar et al. showed ketorolac reduced shoulder pain more than hyaluronic acid. Ahn et al. found ketorolac and corticosteroids equally effective for pain relief, with ketorolac providing better shoulder mobility at 3 and 6 months. 5. What about ketorolac for osteoarthritis? Ketorolac combined with hyaluronic acid provided faster pain relief than hyaluronic acid alone in thumb carpometacarpal joint osteoarthritis (Koh et al.). Intra-articular ketorolac had similar efficacy to corticosteroids in hip (Park et al., Jurgensmeier et al.) and knee osteoarthritis (Bellamy et al., Xu et al.). Ketorolac injections were more cost-effective compared to corticosteroids (Bellamy et al.). 6. Are ketorolac injections safe? Ketorolac's side effects are similar to other NSAIDs, mainly involving gastrointestinal, renal, and cardiovascular risks. However, localized intra-articular and subacromial injections may reduce systemic exposure. Animal studies suggest ketorolac does not harm cartilage and may protect against inflammatory damage. Mild, transient local pain post-injection is possible but usually resolves without treatment. 7. What are the limitations of ketorolac use? Ketorolac is not suitable for patients with: Renal impairment Gastrointestinal ulcers or bleeding risk Cardiovascular disease or hypertension NSAID hypersensitivity, especially in asthma or chronic urticaria patients Clinicians should assess individual risks before choosing ketorolac injections. 8. How does ketorolac's pharmacokinetics affect its use? Ketorolac has a plasma half-life of about 5.2 to 5.6 hours and is metabolized in the liver. Pharmacokinetics for subcutaneous or intra-articular administration are less defined but systemic absorption occurs. Its relatively short half-life supports repeated dosing if needed. 9. Why consider ketorolac over corticosteroids? Ketorolac avoids corticosteroid-associated risks such as tendon rupture, cartilage damage, and steroid-induced hyperglycemia. It is also more cost-effective, making it a favorable option for patients and healthcare systems. 10. What further research is needed? More large-scale, long-term studies are needed to fully understand ketorolac's intra-articular effects, optimal dosing, and safety profile compared to corticosteroids and other treatments. Summary: Ketorolac injections, whether intra-articular or subacromial, offer a safe, effective, and economical alternative to corticosteroids for managing various musculoskeletal conditions. This makes ketorolac an important option in pain management and inflammation control.     Reference: Kiel J, Applewhite AI, Bertasi TGO, Bertasi RAO, Seemann LL, Costa LMC, Helmi H, Pujalte GGA. Ketorolac Injections for Musculoskeletal Conditions: A Narrative Review. Clinical Medicine & Research. 2024;22(1):19-27. DOI: https://doi.org/10.3121/cmr.2024.1847 Disclaimer: This Podcast, website and any content from NRAP Academy (PMRexam.com) otherwise known as Qbazaar.com, LLC is  for general informational purposes only and does not constitute the practice of medicine, nursing or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast or materials linked from this podcast is at the user's own risk. Professionals should conduct their own fact finding, research, and due diligence to come to their own conclusions for treating patients. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professionals for any such conditions.    

Hosts Ryan Baxter and Maris Schneider chat with Geneva Herold, a MSc student in the Department of Physiology and Pharmacology. Geneva studies patients who are at high risk of developing osteoarthritis in their knees due to a previous injury, like an ACL tear. She is studying the cells in a special tissue in the joint called the synovium, which she hopes will help us better understand why some patients develop osteoarthritis and why some don't.   Geneva discusses graduate student life, both in and out of the lab, with Ryan and Maris. Learn more about the lab Geneva works in! https://www.schulich.uwo.ca/appletonlab/   Rcorded on Tuesday, July 29, 2025 Produced by Mark Ambrogio Theme song provided by FreeBeats.io (Produced by WhiteHot)

Did you know your beliefs about osteoarthritis could be making your symptoms worse? In this re-aired episode from Season 5, Episode 1 of Joint Action, physiotherapist and health communication expert Dr Ben Darlow joins us to explore how common misconceptions - like “wear and tear” or “bone on bone” - can limit your activity and shape your treatment choices. We discuss the power of language, the importance of hope, and how better understanding can help you take control of your health. Whether you're living with osteoarthritis, supporting someone who is, or working in healthcare, this conversation is a must-listen.RESOURCESLiving with osteoarthritis is a balancing act: an exploration of patients' beliefs about knee painThe osteoarthritis knowledge scaleCONNECT WITH USTwitter: @ProfDavidHunter @jointactionorgEmail: hello@jointaction.infoWebsite: www.jointaction.info/podcastIf you enjoyed this episode, don't forget to subscribe to learn more about osteoarthritis from the world's leading experts! And please let us know what you thought by leaving us a review! Hosted on Acast. See acast.com/privacy for more information.

On this episode of Vitality Radio, Jared shares a personal story about his battle with tendonitis and the natural joint supplement that surprised even him with rapid, lasting relief. If you suffer from tendon or ligament issues like tennis elbow, joint pain, or even osteoarthritis, this show is a must-listen. Jared dives deep into the science behind Omne Diem's Connective Tissue TLC, highlighting how three targeted ingredients stimulate fibroblasts, increase elastin, and slow cartilage breakdown. You'll also hear about the joint-lubricating benefits of Baxyl®, a bioidentical hyaluronic acid that Jared calls his go-to for arthritis support. Whether you're an athlete, weekend warrior, or just want to protect your joints as you age, this episode will give you a natural edge.Products:Omne Diem Connective Tissue TLCBaxyl® Hyaluronic AcidOmega-3MSMCuramedCBD - Call to order 801.292.6662Visit the podcast website here: VitalityRadio.comYou can follow @vitalitynutritionbountiful and @vitalityradio on Instagram, or Vitality Radio and Vitality Nutrition on Facebook. Join us also in the Vitality Radio Podcast Listener Community on Facebook. Shop the products that Jared mentions at vitalitynutrition.com. Let us know your thoughts about this episode using the hashtag #vitalityradio and please rate and review us on Apple Podcasts. Thank you!Just a reminder that this podcast is for educational purposes only. The FDA has not evaluated the podcast. The information is not intended to diagnose, treat, cure, or prevent any disease. The advice given is not intended to replace the advice of your medical professional.

Schau dir das Video auf YouTube an und abonniere den Kanal, um keine neue Folge mehr zu verpassen.ZusammenfassungIn dieser Episode enthüllt Julia Tulipan, warum Eiweiß weit mehr als nur ein Baustein für Muskeln ist – es ist der unterschätzte Schlüssel zu deiner gesamten Gesundheit! Viele von uns leiden unbewusst unter einem Eiweißmangel, der sich in Symptomen wie chronischer Müdigkeit, Heißhungerattacken, schlechtem Schlaf oder Problemen mit Haut und Bindegewebe äußert. Julia räumt mit den gängigen Mythen auf und zeigt, dass ausreichend Protein nicht nur essenziell für Zell- und Gewebereparatur ist, sondern auch für die Produktion wichtiger Enzyme, Hormone und Antikörper, die dein Immunsystem stärken.Erfahre, wie Protein als der sättigendste Makronährstoff wirkt und dir dabei hilft, deine Gesamtkalorienzufuhr natürlich zu regulieren. Julia erklärt den "spezifischen Aminosäurehunger" und warum dein Körper bei einem Eiweißmangel ständig nach mehr Nahrung verlangt – oft in Form von ungesunden Cravings. Du lernst, wie du deinen individuellen Proteinbedarf ganz einfach berechnest (mind. 1,6g pro kg Körpergewicht) und welche Mindestmengen für Frauen und Männer gelten, um von den vollen Vorteilen zu profitieren.Ist zu viel Eiweiß schädlich? Julia beleuchtet die aktuelle Forschung und gibt Entwarnung für nierengesunde Erwachsene: Ein "zu viel" gibt es nicht! Zudem spricht sie über die Herausforderungen, den Proteinbedarf rein pflanzlich zu decken, und welche Warnsignale auf einen Mangel hindeuten, inklusive des wichtigen Blutwerts "Gesamteiweiß". Am Ende gibt Julia einen unkomplizierten Praxistipp an die Hand, wie du deine Eiweißzufuhr im Alltag ganz einfach erhöhen kannst, um schon bald mehr Energie und Wohlbefinden zu erleben. Steigere deine Gesundheit – Schritt für Schritt!Was du in dieser Episode lernst

In this special episode of the Live Yes! With Arthritis podcast — recorded at the JA Family Summit — the Auslander family joins us to explore how JA impacts the family dynamic, the challenges it presents, ways to cope and build support, some silver linings and more. *Visit the Live Yes! With Arthritis Podcast episode page to get show notes, additional resources and read the full transcript: https://arthr.org/LiveYes_Ep134 (https://arthr.org/LiveYes_Ep134) * We want to hear from you. Tell us what you think about the Live Yes! With Arthritis Podcast. Get started by emailing podcast@arthritis.org (podcast@arthritis.org). Special Guest: Jessica Auslander, MA, PhD, LCMHC, LCAS, NCC, BC-TMH.

Copenhagen Health Week PhD Pitching Competition. Send Abstract på max 250 ord til Bjerre-Bastos@dadlnet.dk inden 15. september 2025.The art of sharing: https://pubmed.ncbi.nlm.nih.gov/40632595/ REFERENCER:https://healthscience.institute/2025/05/07/bryan-johnsons-top-11-health-essentials-ranked/https://ugeskriftet.dk/videnskab/steroidblokadehttps://pubmed.ncbi.nlm.nih.gov/40554037/https://pubmed.ncbi.nlm.nih.gov/40544946/https://pubmed.ncbi.nlm.nih.gov/38574801/Effektstørrelserhttps://www.strongerbyscience.com/heuristics-effect-sizes/Manifest om træningsvolumen: https://www.strongerbyscience.com/volume/ 

Story at-a-glance Osteoarthritis develops slowly from cartilage breakdown in weight-bearing joints, while rheumatoid arthritis is an autoimmune attack that causes rapid, symmetrical joint inflammation Morning stiffness lasting over an hour, fatigue, and fever indicate rheumatoid arthritis; brief stiffness that improves with movement suggests osteoarthritis instead Rheumatoid arthritis typically strikes small joints symmetrically (both wrists, hands) while osteoarthritis affects single joints like knees, hips, and spine asymmetrically Eliminating inflammatory vegetable oils, boosting vitamin K2 intake and sipping bone broth help rebuild cartilage and reduce joint inflammation naturally Supporting mitochondrial health calms autoimmune inflammation by increasing your body's natural "off switch" for inflammatory responses and joint damage

Join @coach.noush_dpt as she discusses rosk factors of osteoarthritis-especially how we can address the genetic component of it with patients! If you found this content helpful, go to https://PTonICE.com to check out our collection of Free Resources like the MMOA Digest our Bi-Weekly Research Email that goes out to thousands of clinicians.  

Contrary to popular belief, osteoarthritis may not just be the result of wear and tear accrued over the course of a long life. New evidence points to a deeper evolutionary explanation for why our joints ache in old age. Let's take a look.

In this episode of the Live Yes! With Arthritis podcast, two moms with arthritis discuss their prepartum, pregnancy, childbirth, postpartum experiences and more. *Visit the Live Yes! With Arthritis Podcast episode page to get show notes, additional resources and read the full transcript: https://arthr.org/LiveYes_Ep133 (https://arthr.org/LiveYes_Ep133) * We want to hear from you. Tell us what you think about the Live Yes! With Arthritis Podcast. Get started by emailing podcast@arthritis.org (podcast@arthritis.org). Special Guest: Natalie Decker.

What if your creaky knees could literally regrow their cushioning instead of relying on painkillers or risky surgeries? With over 528 million people worldwide battling osteoarthritis – a crisis costing $500 billion in lost joy and productivity – we're ditching the duct-tape fixes. Dive into the science turning belly fat into cartilage-repairing stem cells and amniotic fluid exosomes that text your joints to heal. Discover how patients are seeing 94% less pain and 2mm of new cartilage growth – all while avoiding the operating room. And stick around: We'll reveal how a cream might soon deliver stem cell magic straight to your sofa… no needles required. Your body's repair manual just got a groundbreaking rewrite!Special Guest: Grant Townsend – CEO and developer of NuvoCell topical regenerativemedicine

Do your knees hurt when you stand up? Are you losing range of motion in your hips? Have you been told you have osteoarthritis—but left without real guidance or solutions? You're not alone. When I was first diagnosed with hip osteoarthritis, I didn't even know what it meant. A quick online search gave me generic advice like “lose weight,” which as an athletic person was the last thing I needed to do. Maybe you're in the same boat—searching for better answers. That's why I invited Professor Ali Mobasheri to the show. He's one of the world's leading experts on osteoarthritis, aging, and joint health—and in this conversation, he breaks down what we really need to know about OA and can we reverse it, especially during midlife and menopause. We cover: What osteoarthritis actually is and how it differs from other types of arthritis and osteoporosis Why osteoarthritis is not just a “wear and tear” condition How widespread osteoarthritis truly is—and why the numbers are underestimated How menopause influences joint health and increases OA risk Why younger adults are increasingly being diagnosed Whether it's possible to reverse osteoarthritis Which treatments and holistic strategies are most promising Why research around hormone therapy and OA is still lacking Professor Ali Mobasheri is a globally recognized expert in musculoskeletal biology and osteoarthritis research. He is a Professor of Musculoskeletal Biology at the University of Oulu in Finland and a Past President of the Osteoarthritis Research Society International (OARSI). Chief Researcher & International Adviser at the State Research Institute Centre for Innovative Medicine in Lithuania He is an active member of the International Cartilage Regeneration & Joint Preservation Society (ICRS). His research explores the intersection of inflammation, metabolism, and joint aging, with a focus on early diagnosis and prevention. He also serves as an adviser to the World Health Organization and sits on numerous scientific advisory boards, including those focused on osteoarthritis, osteoporosis, and regenerative medicine. He has published over 400 scientific papers and holds an h-index of 78—an extraordinary achievement in academic research. ORCID iD: 0000-0001-6261-1286  https://orcid.org/0000-0001-6261-1286  Scopus Author Identifier: 7003311894  https://www.scopus.com/authid/detail.uri?authorId=7003311894  https://www.oulu.fi/en/research-groups/biomarkers-and-immunometabolism-musculoskeletal-health-and-ageing Contact Ali Mobasheri: https://www.linkedin.com/in/ali-mobasheri-68009712/   Give thanks to our sponsors: Qualia senolytics and brain supplements. 15% off with code ZORA here.  Try Vitali skincare. 20% off with code ZORA here. Get Primeadine spermidine by Oxford Healthspan. 15% discount with code ZORA ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠. Get Mitopure Urolithin A by Timeline. 20% discount with code ZORA at https://timeline.com/zora Try Suji to improve muscle 10% off with code ZORA at TrySuji.com https://trysuji.com Get Magnesium Breakthrough by Bioptimizers. 10% discount with code HACKMYAGE at https://bioptimizers.com/hackmyage Try OneSkin skincare with code ZORA for 15% off https://oneskin.pxf.io/c/3974954/2885171/31050 Join ⁠⁠⁠Biohacking Menopause⁠⁠⁠ before July 1, 2025 to win free Vitali Skincare! 20% off with code ZORA at VitaliSkincare.com   Join the Hack My Age community on: Facebook Page: ⁠⁠⁠⁠⁠@⁠Hack My Age⁠     Facebook Group: ⁠⁠⁠⁠⁠⁠@⁠Biohacking Menopause⁠⁠⁠⁠⁠⁠ ⁠  Private Women's Only Support Group: https://hackmyage.com/biohacking-menopause-membership/ Instagram: ⁠⁠⁠⁠⁠@⁠HackMyAge⁠    Website: ⁠⁠⁠⁠⁠⁠HackMyAge.com⁠    https://hackmyage.com  

Losing extra weight is important for managing arthritis. Hear a rheumatologist explain why and discuss tools to help, including medication, surgery and lifestyle changes. *Visit the Live Yes! With Arthritis Podcast episode page to get show notes, additional resources and read the full transcript: https://arthr.org/LiveYes_Ep132 (https://arthr.org/LiveYes_Ep132) * We want to hear from you. Tell us what you think about the Live Yes! With Arthritis Podcast. Get started by emailing podcast@arthritis.org (podcast@arthritis.org). Special Guest: Dr. Brian Andonian.

In this episode of Joint Action, Professor David Hunter is joined by Dr. Stephanie Mathies and Dr. Giovanni Ferreira to unpack the cost-effectiveness of osteoarthritis treatments. They discuss the results of their recent systematic review, which analysed over 100 studies to identify which guideline-recommended treatments provide the best value for money. From exercise and medications to injections and surgery, they explore which interventions are truly cost-effective - and which may not be worth the spend. Learn why “simple things” like exercise and education still offer the most value, and what this means for patients, clinicians, and healthcare policy. RESOURCESArticle:The cost-effectiveness of guideline-recommended treatments for osteoarthritis: A systematic review: https://www.oarsijournal.com/article/S1063-4584(25)00972-0/abstractCONNECT WITH USTwitter: @ProfDavidHunter @jointactionorgInstagram: @osteoarthritisresearchgroupEmail: osteoarthritis.research@sydney.edu.auWebsite: www.jointaction.info/podca Hosted on Acast. See acast.com/privacy for more information.

  We unpack the UN Scientific Advisory Board Brief on Aging—from telomeres and epigenetic clocks

Musculoskeletal disorders are one of the most important challenges of modern medicine worldwide. They are often attributed to maladaptations of our body to our peculiar form of locomotion, upright bipedalism. This lecture will explore the evolutionary origin of major musculoskeletal disorders such as back problems and hip joint osteoarthritis. I will show that these problems represent a relatively recent phenomenon, occurring only during the last few decades, and thus are unrelated to our skeletal adaptations. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 40696]

Musculoskeletal disorders are one of the most important challenges of modern medicine worldwide. They are often attributed to maladaptations of our body to our peculiar form of locomotion, upright bipedalism. This lecture will explore the evolutionary origin of major musculoskeletal disorders such as back problems and hip joint osteoarthritis. I will show that these problems represent a relatively recent phenomenon, occurring only during the last few decades, and thus are unrelated to our skeletal adaptations. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 40696]

Musculoskeletal disorders are one of the most important challenges of modern medicine worldwide. They are often attributed to maladaptations of our body to our peculiar form of locomotion, upright bipedalism. This lecture will explore the evolutionary origin of major musculoskeletal disorders such as back problems and hip joint osteoarthritis. I will show that these problems represent a relatively recent phenomenon, occurring only during the last few decades, and thus are unrelated to our skeletal adaptations. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 40696]

Musculoskeletal disorders are one of the most important challenges of modern medicine worldwide. They are often attributed to maladaptations of our body to our peculiar form of locomotion, upright bipedalism. This lecture will explore the evolutionary origin of major musculoskeletal disorders such as back problems and hip joint osteoarthritis. I will show that these problems represent a relatively recent phenomenon, occurring only during the last few decades, and thus are unrelated to our skeletal adaptations. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 40696]

Musculoskeletal disorders are one of the most important challenges of modern medicine worldwide. They are often attributed to maladaptations of our body to our peculiar form of locomotion, upright bipedalism. This lecture will explore the evolutionary origin of major musculoskeletal disorders such as back problems and hip joint osteoarthritis. I will show that these problems represent a relatively recent phenomenon, occurring only during the last few decades, and thus are unrelated to our skeletal adaptations. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 40696]

Musculoskeletal disorders are one of the most important challenges of modern medicine worldwide. They are often attributed to maladaptations of our body to our peculiar form of locomotion, upright bipedalism. This lecture will explore the evolutionary origin of major musculoskeletal disorders such as back problems and hip joint osteoarthritis. I will show that these problems represent a relatively recent phenomenon, occurring only during the last few decades, and thus are unrelated to our skeletal adaptations. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 40696]

Phenotypic variation within the skeleton has biological, behavioral, and biomedical functional implications for individuals and species. Thus, it is critical to understand how genomic, environmental, and mediating regulatory factors combine and interact to drive skeletal trait development and evolution. One way to do this is by studying skeletal diseases that disrupt skeletal function — like osteoarthritis (OA) which is a chronic disorder characterized by the degradation of cartilage and underlying bone in joints and can lead to severe pain and mobility limitations. This talk will discuss what is known about OA in humans and other primates, as well as recent advances that are further informing these topics. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 40695]

Phenotypic variation within the skeleton has biological, behavioral, and biomedical functional implications for individuals and species. Thus, it is critical to understand how genomic, environmental, and mediating regulatory factors combine and interact to drive skeletal trait development and evolution. One way to do this is by studying skeletal diseases that disrupt skeletal function — like osteoarthritis (OA) which is a chronic disorder characterized by the degradation of cartilage and underlying bone in joints and can lead to severe pain and mobility limitations. This talk will discuss what is known about OA in humans and other primates, as well as recent advances that are further informing these topics. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 40695]

Phenotypic variation within the skeleton has biological, behavioral, and biomedical functional implications for individuals and species. Thus, it is critical to understand how genomic, environmental, and mediating regulatory factors combine and interact to drive skeletal trait development and evolution. One way to do this is by studying skeletal diseases that disrupt skeletal function — like osteoarthritis (OA) which is a chronic disorder characterized by the degradation of cartilage and underlying bone in joints and can lead to severe pain and mobility limitations. This talk will discuss what is known about OA in humans and other primates, as well as recent advances that are further informing these topics. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 40695]

Phenotypic variation within the skeleton has biological, behavioral, and biomedical functional implications for individuals and species. Thus, it is critical to understand how genomic, environmental, and mediating regulatory factors combine and interact to drive skeletal trait development and evolution. One way to do this is by studying skeletal diseases that disrupt skeletal function — like osteoarthritis (OA) which is a chronic disorder characterized by the degradation of cartilage and underlying bone in joints and can lead to severe pain and mobility limitations. This talk will discuss what is known about OA in humans and other primates, as well as recent advances that are further informing these topics. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 40695]

Phenotypic variation within the skeleton has biological, behavioral, and biomedical functional implications for individuals and species. Thus, it is critical to understand how genomic, environmental, and mediating regulatory factors combine and interact to drive skeletal trait development and evolution. One way to do this is by studying skeletal diseases that disrupt skeletal function — like osteoarthritis (OA) which is a chronic disorder characterized by the degradation of cartilage and underlying bone in joints and can lead to severe pain and mobility limitations. This talk will discuss what is known about OA in humans and other primates, as well as recent advances that are further informing these topics. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 40695]

Phenotypic variation within the skeleton has biological, behavioral, and biomedical functional implications for individuals and species. Thus, it is critical to understand how genomic, environmental, and mediating regulatory factors combine and interact to drive skeletal trait development and evolution. One way to do this is by studying skeletal diseases that disrupt skeletal function — like osteoarthritis (OA) which is a chronic disorder characterized by the degradation of cartilage and underlying bone in joints and can lead to severe pain and mobility limitations. This talk will discuss what is known about OA in humans and other primates, as well as recent advances that are further informing these topics. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 40695]

Curious about how estrogen affects your joint health during menopause? Ever wondered if there's a link between biohacking and managing osteoarthritis? In this episode, join us as we delve into the world of peptides and surgery recovery with Zora Benhamou, a gerontologist and healthy aging coach. Discover how you can empower yourself with practical strategies for maintaining mobility and deciding if surgery is the right choice. Feeling overwhelmed by the thought of surgery? Struggling to navigate the emotional and physical toll of osteoarthritis? We explore how mindset and community support play crucial roles in recovery and wellness. Zora shares her personal journey through double hip replacement and offers invaluable insights into alternative treatments and pre-surgery preparation. Are you aware of the connection between nutrition, biohacking, and recovery? What role do anti-inflammatory foods, collagen, and amino acids play in your health journey? We discuss these topics and more, offering up so many tips to optimize wellness and embrace aging with confidence! In this episode, we uncover: How estrogen influences joint health during perimenopause and menopause. Why mindset and community support are key in overcoming osteoarthritis. Discover practical biohacking strategies for joint health and recovery. Explore the emotional readiness required for osteoarthritis surgery. Learn about innovative treatments like pentosan polysulfate and stem cell therapy. Get it on the secrets to maintaining joint health and navigate the complexities of osteoarthritis with confidence. Don't miss this opportunity to transform your wellness journey with Zora's expert guidance and personal experiences!   Visit Zora's website.   Sponsors Get 15% off your Primeadine purchase with coupon code KM15 here. Coupon KM20 to get 20% off your order of Vitali Skin Care!     Are you in peri or post menopause and looking to optimize your hormones and health? At Hormone Solutions, we offer telemedicine services and can prescribe in every U.S. state, as well as in British Columbia, Alberta, and Ontario in Canada.   Visit karenmartel.com to explore our comprehensive programs: Bioidentical Hormone Replacement Therapy Individualized Weight Loss Programs  Peptide Therapy for weight loss    Interested in our NEW Peptide Weight Loss Program? Join today and get all the details here.   Join our Women's Peri and Post Menopause Group Coaching Program, OnTrack, TODAY!   To our nursing audience members, our podcasts qualify for nursing CE @ RNegade.pro. Provide # CEP17654.   Your host: Karen Martel Certified Hormone Specialist, Transformational Nutrition Coach, & Weight Loss Expert   Karen's Facebook Karen's Instagram

In this episode of 'Science of Slink,' hosted by Dr. Rosy Boa, the focus is on the details of dancing in pole heels, a theme for June 2025. Dr. Boa outlines essential tips for choosing the right shoes, including the benefits of platforms, the significance of a sturdy stiletto, and the importance of proper shoe fit. She delves into the mechanics of balance, the challenges posed by the additional weight of heels, and strategies to avoid foot cramps. Additionally, Dr. Boa emphasizes the importance of acknowledging the roots of pole dancing in strip clubs and supporting sex workers, highlighting her studio's monthly contributions to various support organizations. Lastly, practical advice is offered on warming up properly to prevent foot cramps and ensuring better performance while dancing in heels.Are you a pole nerd interested in trying out online pole classes with Slink Through Strength? We'd love to have you! Use the code “podcast” for 10% off the Intro Pack and try out all of our unique online pole classes: https://app.acuityscheduling.com/catalog/25a67bd1/?productId=1828315&clearCart=true Chapters:00:00 Introduction and Theme Announcement00:51 Acknowledging the Roots of Pole Dancing01:49 The Mechanics of Dancing in Heels06:16 Choosing the Right Pole Heels12:47 Preventing Foot Cramps and Injuries16:19 Addressing Bunions and Final ThoughtsCitations:More information on the intrinsic muscles of the footCard, R. K., & Bordoni, B. (2023). Anatomy, Bony Pelvis and Lower Limb, Foot Muscles. In StatPearls [Internet]. StatPearls Publishing.Despite popular belief there is no strong scientific evidence that shoes or high heels cause bunions.Nix, S. E., Vicenzino, B. T., Collins, N. J., & Smith, M. D. (2012). Characteristics of foot structure and footwear associated with hallux valgus: a systematic review. Osteoarthritis and cartilage, 20(10), 1059-1074.Not even if you dance in shoes (including pointe shoes!).Kennedy, J. G., & Collumbier, J. A. (2008). Bunions in dancers. Clinics in sports medicine, 27(2), 321-328.Bunions seem to be mostly genetic.Coughlin, M. J., & Jones, C. P. (2007). Hallux valgus: demographics, etiology, and radiographic assessment. Foot & ankle international, 28(7), 759-777. Hannan, M. T., Menz, H. B., Jordan, J. M., Cupples, L. A., Cheng, C. H., & Hsu, Y. H. (2013). High heritability of hallux valgus and lesser toe deformities in adult men and women. Arthritis care & research, 65(9), 1515-1521. Piqué-Vidal, C., Solé, M. T., & Antich, J. (2007). Hallux valgus inheritance: pedigree research in 350 patients with bunion deformity. The Journal of foot and ankle surgery, 46(3), 149-154.

In this episode of the Live Yes! With Arthritis podcast, we'll explore how to use the right food and your overall nutrition to maximize its benefits for your arthritis. *Visit the Live Yes! With Arthritis Podcast episode page to get show notes, additional resources and read the full transcript: https://arthr.org/LiveYes_Ep131 (https://arthr.org/LiveYes_Ep131) * We want to hear from you. Tell us what you think about the Live Yes! With Arthritis Podcast. Get started by emailing podcast@arthritis.org (podcast@arthritis.org). Special Guest: Ruth Frechman.

In this week's episode of Joint Action, Professor David Hunter is joined by Dr Sarah Kobayashi, a lecturer in anatomy and osteoarthritis researcher, to talk about the power of walking - especially for people with osteoarthritis.Sarah shares her insights into the many health benefits of walking, why it's so important for joint health, and how to overcome common barriers to getting started. She also introduces the CASCADE-OA study (Community bAsed phySical aCtivity AnD sElf-management for OsteoArthritis), a 12-month clinical trial exploring the effectiveness of a self-directed walking program, Walk With Ease Australia, in improving physical activity levels and managing symptoms for those with hip or knee osteoarthritis.Whether you're new to walking or looking to establish a sustainable routine, this episode offers practical advice and motivation to help you take that first step.RESOURCES Learn more about the CASCADE-OA study and check your eligibility:CASCADE-OA Study Overview: www.osteoarthritisresearch.com.au/cascadeoa-study-overviewAsk your local arthritis organisation about Walk With Ease or the CASCADE-OA study: Arthritis Australia – www.arthritisaustralia.com.au/state-offices/Additional resources:Versus Arthritis Walking Guide (UK): www.versusarthritis.org/about-arthritis/exercising-with-arthritis/exercises/walkingHeart Foundation Walking Groups (Australia) – walking.heartfoundation.org.auParkrun Australia: www.parkrun.com.auCONNECT WITH US Twitter: @ProfDavidHunter @jointactionorgInstagram: @osteoarthritisresearchgroupEmail: osteoarthritis.research@sydney.edu.auWebsite: www.jointaction.info/podcast Hosted on Acast. See acast.com/privacy for more information.

In this episode of Well Wisconsin Radio physical therapist Molly Gill explains how movement can help manage and improve chronic conditions like diabetes, heart disease, arthritis, and chronic pain. We dive into the physical benefits of regular activity, including reduced inflammation, improved joint mobility, and better overall function. Molly offers practical advice on safely incorporating movement into daily routines and overcoming common barriers, highlighting the long-term advantages of staying active for managing chronic health conditions. The information in this podcast does not provide medical advice, diagnosis, or treatment. It should not be used as a substitution for healthcare from a licensed healthcare professional. Consult with your healthcare provider for individualized treatment or before beginning any new program.Resources:Talk to a health coach individually or sign up for group coaching today by calling 800-821-6591.Move For A Million Challenge-Get started today by logging into your Well Wisconsin account at www.webmdhealth.com/wellwisconsin and clicking get moving now on the move for a million card.MyFitness Pal App.Tiny Habits: The Small Changes That Change Everything by B.J Fogg PhD.The Arthritis Foundation's Guide to Good Living with Osteoarthritis by The Arthritis Foundation.

OvertureTi is designed in a way that allows you step by step to avoid a total knee [replacement] because it’s so bone-sparing,” Overture Orthopaedics cofounder Riley Williams tells Bloomberg Intelligence. In this Vanguards of Health Care podcast episode, Williams and CEO James Kim sit down with BI analyst Matt Henriksson to talk about Overture, the development of focalplasty and its benefits over total knee replacement as a minimally invasive treatment option. They also discuss the importance of treating osteoarthritis early in the disease progression. Additionally, tune in to learn how it was once cheaper for Kim to hand-deliver the implants and tools instead of using overnight delivery, and about Dr. Williams’ time as a consultant for Bill Hader’s character in the movie Trainwreck.See omnystudio.com/listener for privacy information.

Canine osteoarthritis — or OA — affects about 20% of dogs older than one…

Canine osteoarthritis — or OA — affects about 20% of dogs older than one year and up to 80% of dogs over eight years of age. However, only about one...

Nutrition Nugget! Bite-size bonus episodes offer tips, tricks and approachable science. This week, Jenn is talking about Rutin, a powerful plant pigment that could transform your health with its antioxidant punch. It is found in foods like apples and buckwheat, so it teams up with vitamin C for surprising benefits. How might this little-known nutrient boost your brain, heart, blood pressure and more? What's one food you already eat that could be packing this hidden benefit? Tune in to find out! Like what you're hearing? Be sure to check out the full-length episodes of new releases every Wednesday.  Have an idea for a nutrition nugget?  Submit it here: https://asaladwithasideoffries.com/index.php/contact/       RESOURCES:Become A Member of Salad with a Side of FriesJenn's Free Menu PlanA Salad With a Side of FriesA Salad With A Side Of Fries MerchA Salad With a Side of Fries InstagramNutrition Nugget: Quercetin

Osteoporosis is a silent disease. There is no pain or other symptoms but inflammation in the gut and joints is a risk factor. Learn about your risks and what you can do for osteoporosis from rheumatologist Dr. Diana Sandler. Join host Corinne Rutkowski, a third year medical student, as she explores the relationship between osteoporosis and psoriasis with leading bone health expert and rheumatologist Dr. Diana Sandler. Listen as they discuss the difference between osteoporosis and osteoarthritis, bone density testing, how prolonged inflammation is a key risk factor especially for psoriatic arthritis, along with treatments and actions you can take to minimize your risk of osteoporosis and fractures.   Do what you can to protect your bone health and function as you age. Timestamps: (00:00) Intro to Psound Bytes & guest welcome rheumatologist Dr. Diana Sandler. (01:23) Risk factors and difference between osteoporosis and osteopenia. (03:10) Difference between osteoporosis and osteoarthritis, which are often confused. (04:17) Diagnosis process for osteoporosis. (06:11) Risk factors for development of osteoporosis. (07:57) Is it possible to have osteoporosis or osteopenia and psoriatic arthritis together? (09:44) The role of osteoclast and osteoblasts in bone formation. (12:21) Treatment of osteoporosis. (14:10) Importance of vitamin D and calcium in the prevention of osteoporosis. (15:57) Activities that strengthen the muscles and bones to slow progression of osteoporosis. (17:08) Precautions and tips for avoiding falls. (18:59) Schedule appointments and ask for referrals early. 4 Key Takeaways: ·       Osteoporosis and osteoarthritis are two distinct diseases that affect joints and bone. ·       There are many factors that impact the development of osteoporosis including inflammatory diseases such as psoriatic arthritis, lifestyle risks, family history, use of steroids, hormone deprivation, and more. ·       Preventive use of bisphosphonates and other treatment strategies can be implemented to address the breakdown of bone in osteoporosis. ·       Various precautions can be taken to minimize and avoid falls. Guest Bio: Dr. Diana Sandler is a rheumatologist at Endeavor Health in Chicago and is a Clinical Assistant Professor at the University of Chicago Pritzker School of Medicine where she is a leading expert in osteoporosis, psoriatic disease, and other immune-mediated diseases. Dr. Sandler is the Director of the Bone Health Center at Endeavor Health. She is also a board member of the National Psoriasis Foundation and in 2023 received the NPF Provider of the Year award in Rheumatology. Dr. Sandler is passionate about patient education and integrative team approaches when it comes to caring for patients with complex and multilevel diseases such as psoriatic arthritis, psoriasis and osteoporosis.

What if you could bounce back from surgery or an injury faster, stronger, and healthier than ever? In this Salad with a Side of Fries episode, gerontologist and biohacker Zora Benhamou joins health coach Jenn Trepeck for a deep dive into surgery and injury recovery, biohacks, and minimizing scars—the essential nutrients for optimizing your healing journey post surgery. Together, they bust myths around menopause, aging, and nutrition while unpacking the science behind inflammation reduction, amino acid supplementation, peptide therapy, and more. From osteoporosis prevention to scar management, Zora shares expert strategies to supercharge recovery and reclaim vitality at any age. Whether preparing for surgery or simply wanting to boost your longevity and performance, this conversation delivers actionable tools for real-life wellness.The Salad With a Side of Fries podcast is hosted by Jenn Trepeck, who discusses wellness and weight loss for real life, clearing up the myths, misinformation, bad science & marketing surrounding our nutrition knowledge and the food industry. Let's dive into wellness and weight loss for real life, including drinking, eating out, and skipping the grocery store.IN THIS EPISODE: (05:15) Zora's story of two hip replacements (in three months) and super-charged surgery recovery through muscle maintenance and protein intake(11:02) Delaying surgery until quality of life is significantly impacted is deeply a personal decision(16:47) Pre-surgery mental preparation and muscle building/maintenance within mobility limits(20:00) Nutrition focus: high protein intake, amino acids, whole foods and nutrient-rich supplements for surgery recovery(22:34) Long-term nutritional deficiencies contribute to bone health issues; commitment to nutrition needed, and a radiation protection hack(29:22) Managing surgery recovery by reducing inflammation(36:33) Discussion of post-surgery nutrition focuses on protein, collagen, anti-inflammatory foods and scar treatments(44:32) Recovery strategies apply to various surgeries, and having a positive mindset for surgery recoveryKEY TAKEAWAYS:Pre-surgery muscle maintenance is critical. Build and maintain muscle mass before surgery through exercise, even with limited mobility, to enhance surgery recovery and quality of life before and after surgery.Increase protein intake before and after surgery to support muscle growth, tissue repair, and ligament recovery.Eliminate processed foods and prioritize whole foods to reduce inflammation and aid healing. Use supplements for radiation protection.To improve scar texture and appearance, apply copper peptides, rosehip oil, and silicone tape, and consider micro needling or lasers.QUOTES: (17:27) “Going into that surgery with muscle mass and strength is so important for your recovery. That is key number one.” - Zora Benhamou(22:49) “When our body is not getting all the nutrients it needs to function, it will pull them from our bones.” - Jenn Trepeck(35:59) “In post-op procedures, because of various things, people often are not hungry, but we need nutrients to heal.” - Jenn Trepeck(45:34) “Try to turn it around to a positive and say, this is a great time to work on my health, focus on recovery, and build a better person. - Zora  Benhamou(46:20) "It's never too late to start."  - Jenn TrepeckRESOURCES:Become A Member of Salad with a Side of FriesJenn's Free Menu PlanA Salad With a Side of FriesA Salad With A Side Of Fries MerchA Salad With a Side of Fries InstagramReverse Menopause Weight Gain: New Blood Sugar Balancing Tips – Jenn Trepeck – Hack My AgeNutrition Nugget: Methylene BlueThe Algae Advantage (feat. Catharine Arnston)Bone Health & the Problem with Bone Density Scans (feat. Dr. John Neustadt)GUEST RESOURCES:Hack My Age - WebsiteBiohacking Menopause - Membership ProgramZora Benhamou Instagram (@hackmyage)Hack My Age - FacebookZora The Explorer (@hackmyage) | TikTokHack My Age - YouTubeBiohacking Menopause Support Group | FacebookGUEST BIOGRAPHY:Zora Benhamou is a gerontologist and biohacker dedicated to challenging menopause stigma and ageist stereotypes. As the dynamic host of the Hack My Age podcast, she focuses on empowering women navigating the menopausal transition through biohacking techniques and information from forward-thinking experts.At 54 years old, Zora embodies the essence of a digital nomad and is a passionate menopause educator. She is the visionary behind HackMyAge.com and the author of the Longevity Master Plan and cookbook, "Eating For Longevity," offering invaluable resources and programs for women in peri-menopause and post-menopause. Zora's commitment to normalizing menopause conversations is evident through creating the support group and community, Biohacking Menopause. She completed the Institute of Bioidentical Medicine's Menopause Method training and Dr. Stacey Sims' Menopause for Athletes course and is an active member of esteemed organizations such as the Gerontological Society of America, the Aging Society of America, the British Menopause Society and the European Menopause and Andropause Society. With a Master's degree in Gerontology from the prestigious University of Southern California, Zora's expertise extends to sports nutrition coaching and Oxygen Advantage Breathing instruction, further enriching her holistic approach to women's wellness.

Symptoms of inflammatory arthritis may be confused with other conditions with similar symptoms. Find out about some of them and what to do if you experience new symptoms. *Visit the Live Yes! With Arthritis Podcast episode page to get show notes, additional resources and read the full transcript: https://arthr.org/LiveYes_Ep130 (https://arthr.org/LiveYes_Ep130) * We want to hear from you. Tell us what you think about the Live Yes! With Arthritis Podcast. Get started by emailing podcast@arthritis.org (podcast@arthritis.org). Special Guest: Eric Ruderman, MD.

Jochen Schleese of Schleese Saddles joins us to talk about saddle design and fit and Dr. Matt Klotz explains Arthritis in horses and how to treat it. Plus, some weird news, Listen in…HORSES IN THE MORNING Episode 3696 – Show Notes and Links:Hosts: Jamie Jennings of Flyover Farm and Glenn the GeekTitle Sponsor: State Line Tack and Poseidon Animal HealthGuest: Jochen Schleese - Founder, Educator, CMS, CSFT, CSE from Schleese SaddleryGuest: Dr. Matt Klotz, Equine Technical Services Veterinarian of Aurora Pharmaceutical Additional support for this podcast provided by: Daily Dose Equine, Spalding Labs - Code HRN10 to get 10% off, Equine Network and Listeners Like YouTIME STAMPS:06:00 - Daily Whinnies15:30 - Jochen Schleese33:50 - Dr. Matt Klotz50:00 - Weird News

Jochen Schleese of Schleese Saddles joins us to talk about saddle design and fit and Dr. Matt Klotz explains Arthritis in horses and how to treat it. Plus, some weird news, Listen in…HORSES IN THE MORNING Episode 3696 – Show Notes and Links:Hosts: Jamie Jennings of Flyover Farm and Glenn the GeekTitle Sponsor: State Line Tack and Poseidon Animal HealthGuest: Jochen Schleese - Founder, Educator, CMS, CSFT, CSE from Schleese SaddleryGuest: Dr. Matt Klotz, Equine Technical Services Veterinarian of Aurora Pharmaceutical Additional support for this podcast provided by: Daily Dose Equine, Spalding Labs - Code HRN10 to get 10% off, Equine Network and Listeners Like YouTIME STAMPS:06:00 - Daily Whinnies15:30 - Jochen Schleese33:50 - Dr. Matt Klotz50:00 - Weird News

Knowing what kind of arthritis you have is vital to getting the right treatment. Listen to a rheumatologist discuss what arthritis really is and what you should know. *Visit the Live Yes! With Arthritis Podcast episode page to get show notes, additional resources and read the full transcript: https://arthr.org/LiveYes_Ep129 (https://arthr.org/LiveYes_Ep129) * We want to hear from you. Tell us what you think about the Live Yes! With Arthritis Podcast. Get started by emailing podcast@arthritis.org (podcast@arthritis.org). Special Guest: Dr. Lesley Jackson.

Osteoarthritis is the most common form of arthritis in humans and in dogs, and the most common source of chronic pain in dogs. One in four dogs will be diagnosed with arthritis! And don't miss the following topics that Terry will also discuss on this show: Fix Your Swollen Feet and Ankles Can Antibiotics Cause Diabetes? Will You Be Healthy at Age 70? The Benefits of Olive Extract for Your Knees

Revolutionizing Regenerative Medicine: The Power of Mass-Produced Mitochondria: Nutritionist Leyla Muedin explores groundbreaking research on stem cell-based methods to mass-produce human mitochondria, which could revolutionize regenerative and anti-aging medicine. She delves into the science and potential health benefits, discussing how increased mitochondrial production can improve conditions like osteoarthritis, heart disease, and neurodegenerative disorders. Leyla also provides practical advice on ways to enhance mitochondrial health through dietary and supplement strategies, offering listeners actionable steps to boost their health span and lifespan.

Celebrate Nurses Week starting May 6, 2025! Sign up now at ReMarnurse.com/NursesWeek   In this engaging video, Professor Regina Callion, MSN, RN, discusses the critical NCLEX safety points regarding aneurysms. We'll explore what an aneurysm is and why it's crucial for nursing students to understand this topic. Discover the various types of aneurysms, including cerebral, abdominal, and thoracic, and learn how to identify high-risk individuals who need immediate attention.   We'll dive into the underlying causes, such as genetic factors and lifestyle choices, and look at the diagnostic tests used, like CT scans and MRIs. You'll also gain insights into management options ranging from monitoring to surgical interventions, along with essential nursing priorities for patient care.   Don't forget to like, comment, and subscribe for more informative content on nursing and healthcare topics.   Download the ReMar V2 App: ►For iOS: https://apps.apple.com/us/app/remar-v2/id6468063785 ►For Android: https://play.google.com/store/apps/details... ► Find JOBS: http://ReMarNurse.com/jobs ► NCLEX for Africa - http://ReMarNurse.com/KENYA ► Get NCLEX V2: http://www.ReMarNurse.com ►NCLEX V2 Free Trial - http://ReMarNurse.com/free ► FOLLOW ReMar on Instagram: https://www.instagram.com/ReMarNurse/ ► LIKE ReMar on Facebook: https://www.facebook.com/ReMarReview/ ► Subscribe Now on YouTube - http://bit.ly/ReMar-Subscription

If you've been told to “strengthen your core” for back pain, osteoporosis, or spinal arthritis—but don't know where to start—this episode is for you. Discover why the pelvic tilt + exhale is the game-changing core move that builds true spinal stability, reduces pain, and lays the foundation for safe, effective progressions like planks and bird dogs. Let's get your core working with you, not against you!More Resources & LinksFREE 5-Day Core Tune Up - A free mini-course to dramatically improve your functional core strength, create better alignment, and relieve back and hip pain for good!FREE Weekly Jumpstart Newsletter! Master your midlife health in just 3 minutes a week with this easy-to-read newsletterThe Back & Hip Fix 30-day program - Reduce your chronic back & hip pain in less than 10 minutes a day!Follow Megan on InstagramFollow Megan on YouTube