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In this episode, we dive into the complexities of IgG4-Related Disease (IgG4-RD), a mysterious and multi-organ condition that continues to challenge both patients and physicians. Back in January 2024, Dr. John Stone introduced us to the emerging landscape of treatments for IgG4-RD, and today, Dr. Matthew Baker joins us to provide an exciting update. With new therapies on the horizon, we explore the role of B and T cell pathogenesis, the limitations of traditional steroid treatments, and the off-label use of rituximab. We also take a closer look at the promising results from the “Mitigate Trial,” which offers hope for future strategies in managing this enigmatic disease. Join us as we discuss the evolving treatment landscape and what lies ahead for those affected by IgG4-RD.
Nicola Henderson is the CEO of Godstone Farm having had a career at Chessington World of Adventures, Madame Tussauds, Thorpe Park as well as Kidzania. We chat about her role as CEO at Godstone Farm and what this actually involves as well as plans for the future of the business. Nicola shares some interesting events that take place at Godstone Farm. You can see more of what it has to offer at www.godstonefarm.co.uk Your Business Hour podcast is hosted by the founders of Champ Consultants, Chantal and Matthew Baker. They are both accountants and bring a wealth of knowledge, experience, and business tips to their chat. They interview guests who tell their business stories, as well as consider the latest topics in business and finance.New podcasts are released weekly on a Tuesday and you can follow us on:Instagram: @your.businesshourFacebook: @your.businesshour
Ben Rousseau is multi disciplined designer and multi award winning lighting artist specialising in the relationship between material, light and form. Ben work now heavily focuses on the relationship of time and light and we can improve our experiences with time and learning to appreciate more than ever living in the now. Ben's passion can really be felt in our chat and he ideas are amazing. You can find out more about Ben at www.benrousseau.comYour Business Hour podcast is hosted by the founders of Champ Consultants, Chantal and Matthew Baker. They are both accountants and bring a wealth of knowledge, experience, and business tips to their chat. They interview guests who tell their business stories, as well as consider the latest topics in business and finance.New podcasts are released weekly on a Tuesday and you can follow us on:Instagram: @your.businesshourFacebook: @your.businesshour
Dani is a patient, positive and passionate professional organiser who brings bucket-loads of energy to each client. She loves to work with people to help them transform chaotic spaces into organised, calm functional environments they want to spend more time in. She helps them simplify their life, saving them time and bringing joy back into their home.D ani's mission is to help people declutter and shed that excess ‘stuff' from their lives, making space for what truly sparks joy and finding calm in the chaos. You can find out more about Dani and her services at www.danideclutters.co.ukYour Business Hour podcast is hosted by the founders of Champ Consultants, Chantal and Matthew Baker. They are both accountants and bring a wealth of knowledge, experience, and business tips to their chat. They interview guests who tell their business stories, as well as consider the latest topics in business and finance.New podcasts are released weekly on a Tuesday and you can follow us on:Instagram: @your.businesshourFacebook: @your.businesshour
Sally from The Lost Sheep in Caterham shares her stories of her tea room and gift shop. Why she chose a high street shop and not in a shopping centre are just a few topics discussed as well as her plans for the future to help community groups. You can find Sally's shop at www.thelostsheepcaterham.comYour Business Hour podcast is hosted by the founders of Champ Consultants, Chantal and Matthew Baker. They are both accountants and bring a wealth of knowledge, experience, and business tips to their chat. They interview guests who tell their business stories, as well as consider the latest topics in business and finance.New podcasts are released weekly on a Tuesday and you can follow us on:Instagram: @your.businesshourFacebook: @your.businesshour
Brian Lucas started his business in October 1982. He is an IP attorney and there is nothing Brian does not know. He shares with us what a trademark and a patent are as well as more technical matters and what factors need to be considered when applying for a trademark and or a patent. The chat with Brian was a real eye opener for us and so much was learnt. You can find Brian at www.lucas-uk.comYour Business Hour podcast is hosted by the founders of Champ Consultants, Chantal and Matthew Baker. They are both accountants and bring a wealth of knowledge, experience, and business tips to their chat. They interview guests who tell their business stories, as well as consider the latest topics in business and finance.New podcasts are released weekly on a Tuesday and you can follow us on:Instagram: @your.businesshourFacebook: @your.businesshour
Simon Severino has created +2B in additional sales for his clients over the last 21 years. As an advisor who became CEO, he had to learn the importance of working on the business more than in it. He shares his proven templates with high-ticket entrepreneurs using his Strategy Sprints Method. During our conversation, Simon shares some of the ways to accelerate growth for an agile business and these are just some of his tips from his book, Strategy Sprints. You can find Simon at www.strategysprints.comYour Business Hour podcast is hosted by the founders of Champ Consultants, Chantal and Matthew Baker. They are both accountants and bring a wealth of knowledge, experience, and business tips to their chat. They interview guests who tell their business stories, as well as consider the latest topics in business and finance.New podcasts are released weekly on a Tuesday and you can follow us on:Instagram: @your.businesshourFacebook: @your.businesshour
Lee Cooper set up Paradigm 24 that makes sustainable event stands. During our chat Lee explains how the products work, how the business started and the future of the business. The future of events is using Paradigm 24 products that are sustainable and tick all the right boxes.Paradigm 24 won the sustainability award at the Tandridge Business Awards in 2024. You can find Lee at www.paradigm24.co.ukYour Business Hour podcast is hosted by the founders of Champ Consultants, Chantal and Matthew Baker. They are both accountants and bring a wealth of knowledge, experience, and business tips to their chat. They interview guests who tell their business stories, as well as consider the latest topics in business and finance.New podcasts are released weekly on a Tuesday and you can follow us on:Instagram: @your.businesshourFacebook: @your.businesshour
Gaby and Sammy are friends who now run Styled Right together. Styled Right is a fashion and homeware boutique located in church Walk Shopping Centre in Caterham. During our chat we talk about why a business would want to be in a shopping centre, the joys of working with a friend and the plans for the business and their amazing subscription. You can check out their online store at www.styledright.co.uk Your Business Hour podcast is hosted by the founders of Champ Consultants, Chantal and Matthew Baker. They are both accountants and bring a wealth of knowledge, experience, and business tips to their chat. They interview guests who tell their business stories, as well as consider the latest topics in business and finance.New podcasts are released weekly on a Tuesday and you can follow us on:Instagram: @your.businesshourFacebook: @your.businesshour
Kush is an employee at Champ Consultants Limited and he questions Chantal & Matthew about the how, why and much more of Champ Consultants Limited as well as understanding why they run their business with the culture that they do. You can find out more about what they do at www.champconsultants.co.uk and follow Chantal on www.tiktok.com/@toptaxtipsukYour Business Hour podcast is hosted by the founders of Champ Consultants, Chantal and Matthew Baker. They are both accountants and bring a wealth of knowledge, experience, and business tips to their chat. They interview guests who tell their business stories, as well as consider the latest topics in business and finance.New podcasts are released weekly on a Tuesday and you can follow us on:Instagram: @your.businesshourFacebook: @your.businesshour
Kam Dehal is the Group Executive Director, Commercial and Partnerships at Orbital South Colleges. She has worked in further education for over 26 years. Her work involves working with businesses and communities to ensure that training, job opportunities and skills development are aligned so people, students and organisations know how to access the best training solution for them. Life is about learning and developing yourself and others, in bring people and talent together and really does transform lives.Your Business Hour podcast is hosted by the founders of Champ Consultants, Chantal and Matthew Baker. They are both accountants and bring a wealth of knowledge, experience, and business tips to their chat. They interview guests who tell their business stories, as well as consider the latest topics in business and finance.New podcasts are released weekly on a Tuesday and you can follow us on:Instagram: @your.businesshourFacebook: @your.businesshour
Murderer and brothel-keeper? Then why was he standing at the end of Henry VII's deathbed? Relevant Episodes Cameo 23 - Hugh Denys | Tudoriferous S1 - 023 - Edmund de la Pole - 6th Earl of Suffolk | Tudoriferous Sex and Why You Shouldn't | Tudoriferous Join our Patreon family for yet more episodes - Tudoriferous | creating a Podcast discussing the great, good and mad Tudor Era | Patreon
Samatha Tollworthy is the founder of eco-friendly sock company Teddy Locks. She transitioned from a successful career as a wildlife TV producer to become a sustainability advocate. Samantha chats to us about how her experiences ignited a passion for environmental change, leading her to launch Teddy Locks - a brand dedicated to reducing waste through ethically produced socks made from recycled materials and by converting plastic bottles and textile waste into durable products. Samatha's aim is to connect with major airlines to help reduce their CO2 by having lighter socks on board long haul flights. You can find Teddy Locks at www.teddylocks.comYour Business Hour podcast is hosted by the founders of Champ Consultants, Chantal and Matthew Baker. They are both accountants and bring a wealth of knowledge, experience, and business tips to their chat. They interview guests who tell their business stories, as well as consider the latest topics in business and finance.New podcasts are released weekly on a Tuesday and you can follow us on:Instagram: @your.businesshourFacebook: @your.businesshour
Suzie Newbold and William Wilsnagh come with a wealth of knowledge and experience in running a business. They are the support team of Surrey Business who provide a huge range of business support to all businesses in Surrey. We chat about their experiences and they share some examples of how they have supported businesses as well as discovering more about Surrey Business and how they are able to support your business. You can find out more at www.businesssurrey.co.uk Your Business Hour podcast is hosted by the founders of Champ Consultants, Chantal and Matthew Baker. They are both accountants and bring a wealth of knowledge, experience, and business tips to their chat. They interview guests who tell their business stories, as well as consider the latest topics in business and finance.New podcasts are released weekly on a Tuesday and you can follow us on:Instagram: @your.businesshourFacebook: @your.businesshour
Shyam is a seasoned Spiritual Leadership and Mindfulness Coach with nearly 20 years of experience in guiding individuals and communities toward personal growth, resilience and spiritual well-being. Shyan combines the ancient wisdom of Bhakti with modern mindfulness practices and empowers individuals to lead with integrity and purpose. During our chat Shyam shares some insightful thoughts about our mind and the necessity to be part of a community as a business leader, entrepreneur and an individual. We discuss why everyone should have a coach and should undertake some form of meditation. You can find Shyam at www.shyamgovindacoaching.com as well as on Facebook and InstagramYour Business Hour podcast is hosted by the founders of Champ Consultants, Chantal and Matthew Baker. They are both accountants and bring a wealth of knowledge, experience, and business tips to their chat. They interview guests who tell their business stories, as well as consider the latest topics in business and finance.New podcasts are released weekly on a Tuesday and you can follow us on:Instagram: @your.businesshourFacebook: @your.businesshour
Kasper Sierslev is the Chief Creative Officer at ZITE and an award-winning marketer and creative professional. He is an accomplished illustrator and storyboard artist, and a frequent keynote speaker at marketing events. A few years back he co-founded The Danish School of Advertising's Content Marketing class. During our chat we explore the powerful in-house marketing strategies that help businesses adapt and grow. You can find Kasper on Linked In at www.linkedin.com/in/kaspersierslevYour Business Hour podcast is hosted by the founders of Champ Consultants, Chantal and Matthew Baker. They are both accountants and bring a wealth of knowledge, experience, and business tips to their chat. They interview guests who tell their business stories, as well as consider the latest topics in business and finance.New podcasts are released weekly on a Tuesday and you can follow us on:Instagram: @your.businesshourFacebook: @your.businesshour
Chantal and Matthew look at the various tax changes that have been made in the budget and how these affect employees, employers and individuals. Chantal and Matthew are both Chartered Certified Accountants and run Champ Consultants Ltd as well as hosts for Your Business Hour. Chantal is also a Chartered Tax Advisor as well as a Chartered Certified Accountant. You can find out more about what their company does at www.champconsultants.co.ukYour Business Hour podcast is hosted by the founders of Champ Consultants, Chantal and Matthew Baker. They are both accountants and bring a wealth of knowledge, experience, and business tips to their chat. They interview guests who tell their business stories, as well as consider the latest topics in business and finance.New podcasts are released weekly on a Tuesday and you can follow us on:Instagram: @your.businesshourFacebook: @your.businesshour
Dr Daniel Daniel is the crypto trainer that entry-level investors deserve. With a keen focus on breaking down the barriers to entry, Dr. Daniel is committed to demystifying crypto investing and stopping the gatekeeping of knowledge that can make investing in crypto seem impossible to those who are beginners. Dr. Daniel has developed ‘The Crypto Investing Program' and he chats to us about this as well as other crypto matters. No investing in crypto should be undertaken without knowing and understanding all the risks. You can find Dr. Daniel at www.cryptoprogram.caYour Business Hour podcast is hosted by the founders of Champ Consultants, Chantal and Matthew Baker. They are both accountants and bring a wealth of knowledge, experience, and business tips to their chat. They interview guests who tell their business stories, as well as consider the latest topics in business and finance.New podcasts are released weekly on a Tuesday and you can follow us on:Instagram: @your.businesshourFacebook: @your.businesshour
Marc Adams spent nearly 4 decades in corporate and as an entrepreneur transforming and adding value to businesses along the way, taking them from where they were and driving 10X plus the value with a view to some exit at some point.During our chat with Marc, she shares so many tips with us on how to grow the value of your business, how to increase turnover and most importantly how to increase that bottom line profit.You can find Marc at www.acquisitions4you.comYour Business Hour podcast is hosted by the founders of Champ Consultants, Chantal and Matthew Baker. They are both accountants and bring a wealth of knowledge, experience, and business tips to their chat. They interview guests who tell their business stories, as well as consider the latest topics in business and finance.New podcasts are released weekly on a Tuesday and you can follow us on:Instagram: @your.businesshourFacebook: @your.businesshour
With over 11 years of experience in the entertainment industry, Toby Burns is an entrepreneur and CEO of The Silent Disco Company Group, a leading provider of silent disco hire services in the UK and Europe. We chat to Toby about he went from a children entertainer to starting The Silent Disco and where to next. Watch this space! Toby explains to us how he transitioned his time and skills to large scale and stopped swapping time for money. You can find Toby at www.thesilentdiscocompany.co.ukYour Business Hour podcast is hosted by the founders of Champ Consultants, Chantal and Matthew Baker. They are both accountants and bring a wealth of knowledge, experience, and business tips to their chat. They interview guests who tell their business stories, as well as consider the latest topics in business and finance.New podcasts are released weekly on a Tuesday and you can follow us on:Instagram: @your.businesshourFacebook: @your.businesshour
Neil and Dizzy Riches are a husband and wife team who run My Club Europe Plc. Their business started in 2019 and COVID caused it to take a turn and reshape their business. During our chat, we discuss why the decide to operate as a PLC, how they are now the bespoke Teamwear provider for Decathlon UK, their patent and so much more. You can find their website at www.myclubgroup.co.ukYour Business Hour podcast is hosted by the founders of Champ Consultants, Chantal and Matthew Baker. They are both accountants and bring a wealth of knowledge, experience, and business tips to their chat. They interview guests who tell their business stories, as well as consider the latest topics in business and finance.New podcasts are released weekly on a Tuesday and you can follow us on:Instagram: @your.businesshourFacebook: @your.businesshour
Sophie Martin has worked in PR since 1993 across a wide range of sectors as well as running her own PR company. Under the working name of The Word Bird, Sophie tends to focus her attention on local, small businesses needing help with pr, copywriting, marketing, social media and websites. Sophie shares some interesting tips with us on how to keep your business on Google for free as well as the necessities of social media and websites for businesses. We also look into how a BID (Business Improvement District) can help your town or village thrive. You can find Sophie at www.thewordbird.meYour Business Hour podcast is hosted by the founders of Champ Consultants, Chantal and Matthew Baker. They are both accountants and bring a wealth of knowledge, experience, and business tips to their chat. They interview guests who tell their business stories, as well as consider the latest topics in business and finance.New podcasts are released weekly on a Tuesday and you can follow us on:Instagram: @your.businesshourFacebook: @your.businesshour
Vanda James is a partner and head of Birkett's Sevenoaks Family Team. She has nearly 30 years' experience and is the former President of Kent Law Society and is listed in the Citywealth Leaders List. She is an expert in all aspects of family law and specialises in complex financial cases or those with an unusual element. With so many topics to discuss in this category we ask Vanda to explain to us what when we would need to use an family lawyer and this was not just in the case of a divorce or separation. Vanda is also an Oenophile and has completed the Wine and Spirit Education Trust exams to Level 3. You can find Vanda at www.birketts.co.ukYour Business Hour podcast is hosted by the founders of Champ Consultants, Chantal and Matthew Baker. They are both accountants and bring a wealth of knowledge, experience, and business tips to their chat. They interview guests who tell their business stories, as well as consider the latest topics in business and finance.New podcasts are released weekly on a Tuesday and you can follow us on:Instagram: @your.businesshourFacebook: @your.businesshour
Louise Punter became Chief Executive of Surrey Chambers of Commerce following 17 years working in manufacturing and business services. To ensure strong representation of Surrey businesses, Louise sits on many different boards including the One Surrey Growth Board, the Business Leaders forum, the Skills Leadership Forum, the Civilian-Military Partnership Board and works with the Economic Development departments of the county and Borough Councils. Louise chats to us and goes through the 4 main objectives of the Surrey Chamber of Commerce being Connect, Support, Promote and Represent. You can find out more about the Surrey Chamber of Commerce at www.surrey-chambers.co.ukYour Business Hour podcast is hosted by the founders of Champ Consultants, Chantal and Matthew Baker. They are both accountants and bring a wealth of knowledge, experience, and business tips to their chat. They interview guests who tell their business stories, as well as consider the latest topics in business and finance.New podcasts are released weekly on a Tuesday and you can follow us on:Instagram: @your.businesshourFacebook: @your.businesshour
Matthew Heath has over 20 years of experience working in funding, over 10 years in project management and over 5 years of giving direct business support and advice to organisations across the South East of England.We chat to Matthew about Coast 2 Capital and how they support local councils in providing funding and support to local businesses. We consider the benefits of entering awards and how Coast 2 Capital are sponsors of the Tandridge Business AwardsYou can find out more about Coast 2 Capital at www.coast2capital.org.ukYour Business Hour podcast is hosted by the founders of Champ Consultants, Chantal and Matthew Baker. They are both accountants and bring a wealth of knowledge, experience, and business tips to their chat. They interview guests who tell their business stories, as well as consider the latest topics in business and finance.New podcasts are released weekly on a Tuesday and you can follow us on:Instagram: @your.businesshourFacebook: @your.businesshour
Nancy Steidl is an international business consultant and intellectual property law specialist in AI, Robots and Big Data with over 25 years of experience. She is the CEO of The Business Mission.We chat with Nancy about AI in a business and how business need to embrace AI and make it work for them as well as how ChatGPT can work for your business. Nancy shares some tips from her book, released in December 2024, ‘The art of analogies in business, how to start a business in layman's terms'.You can find Rebecca at www.thebusinessmission.com Your Business Hour podcast is hosted by the founders of Champ Consultants, Chantal and Matthew Baker. They are both accountants and bring a wealth of knowledge, experience, and business tips to their chat. They interview guests who tell their business stories, as well as consider the latest topics in business and finance.New podcasts are released weekly on a Tuesday and you can follow us on:Instagram: @your.businesshourFacebook: @your.businesshour
Rebecca started her own recruitment business in 2017 and in 2021 started another business where she uses her recruitment background to help job seekers to become laser focused job getters, she teaches people to maximise the phenomenal power of LinkedIn, understand the hidden job market, build confidence and self-belief. Rebecca shares some tips on how to get the most you of LinkedIn.You can find Rebecca at www.career-garage.co.uk Your Business Hour podcast is hosted by the founders of Champ Consultants, Chantal and Matthew Baker. They are both accountants and bring a wealth of knowledge, experience, and business tips to their chat. They interview guests who tell their business stories, as well as consider the latest topics in business and finance.New podcasts are released weekly on a Tuesday and you can follow us on:Instagram: @your.businesshourFacebook: @your.businesshour
Matt Raad has used a very unconventional method to create financial freedom in his lifetime. He and his wife Liz are website investors, which means they use digital assets to generate cashflow and build wealth. They now teach beginners how to reach 6 and 7 figures incomes through buying, building and renovating websites. Chatting to Matt was intriguing and listening to his some of the insights in how to achieve this were wonderful. You can find Matt at www.eBusinessInstitute.com.auYour Business Hour podcast is hosted by the founders of Champ Consultants, Chantal and Matthew Baker. They are both accountants and bring a wealth of knowledge, experience, and business tips to their chat. They interview guests who tell their business stories, as well as consider the latest topics in business and finance.New podcasts are released weekly on a Tuesday and you can follow us on:Instagram: @your.businesshourFacebook: @your.businesshour
Sarah Hickey is a partner in Birketts' Private Client Advisory Team with over 20 years' experience of private client work. Sarah has particular experience of providing tailored specific advice to individuals and their families on Wills, inheritance tax planning, lifetime gifts, trusts, probate, (administration of estates) intestacy, deeds of variation and powers of attorney. In 2024, Sarah was named as a ‘Leading Individual' by Legal 500. In our chat we discuss the importance of wills and much more especially the stages in your life when you should reassess your wills. You can find Sarah at www.birketts.co.ukYour Business Hour podcast is hosted by the founders of Champ Consultants, Chantal and Matthew Baker. They are both accountants and bring a wealth of knowledge, experience, and business tips to their chat. They interview guests who tell their business stories, as well as consider the latest topics in business and finance.New podcasts are released weekly on a Tuesday and you can follow us on:Instagram: @your.businesshourFacebook: @your.businesshour
Sharlene is the proud owner of C + B by Sharlene in Caterham, Surrey. Her story began over 19 years ago as a Saturday girl in a blinds and curtain store with zero experience or knowledge. C + B by Sharlene is not just a business, it is a platform to create connections, to understand your dreams for your homes and to help you achieve them. Sharlene believes in the value of good old-fashioned, friendly service and a personal touch.You can find her business at https://cb-bysharlene.co.uk/Your Business Hour podcast is hosted by the founders of Champ Consultants, Chantal and Matthew Baker. They are both accountants and bring a wealth of knowledge, experience, and business tips to their chat. They interview guests who tell their business stories, as well as consider the latest topics in business and finance.New podcasts are released weekly on a Tuesday and you can follow us on:Instagram: @your.businesshourFacebook: @your.businesshour
Andy Brown has over 30 years' experience as an award winning adviser and coach for people based businesses. He is also a podcast host and the author of Amazon #1 Best Seller, ‘The Emotional Overdraft: 10 simple changes for balancing business success and wellbeing' a book for entrepreneurs, leaders and founders that articulates the often overlooked mental and physical costs of leadership. During our conversation, Andy explains how we need to make time to learn and how to make time for the matters we put off. He shares with us some tips and truths about life as an entrepreneur and ways to get it right.Here are a few links to some of Andy's information, and his website is:https://emotionaloverdraft.com/Buy the book in the UK - https://www.amazon.co.uk/Emotional-Overdraft-balancing-business-wellbeing/dp/1788605136/Complete the free Emotional Overdraft Self-Assessment -https://emotionaloverdraft.com/self-assesment/Connect with Andy - https://www.linkedin.com/in/andybrownprofile/ Your Business Hour podcast is hosted by the founders of Champ Consultants, Chantal and Matthew Baker. They are both accountants and bring a wealth of knowledge, experience, and business tips to their chat. They interview guests who tell their business stories, as well as consider the latest topics in business and finance.New podcasts are released weekly on a Tuesday and you can follow us on:Instagram: @your.businesshourFacebook: @your.businesshour
Over the past several years, the Canadian Federal Government's budgets have introduced tax changes affecting high-income earners and business owners. This year's budget announcement includes a proposed change to the capital gains inclusion rate. In this episode, John Nicola, Chairman, CEO, and CIO, and Ethan Astaneh, Wealth Advisor | Client Relationship Manager, at Nicola Wealth are joined by Matthew Baker, Partner in Tax at Baker Tilly Canada. They outline key tax considerations and strategies that investors should be aware of as they monitor their long-term financial plans.
Emma Pearce is an experienced marketing consultants and has been running her marketing agency, Pearce Marketing, for over 16 years. Pearce Marketing helps SME business owners feel confident in their marketing strategy and get results. During our conversation with Emma we discuss the marketing strategy needed when dealing with business to business or business to consumers and Emma shares some of her tips with us. You can get two FREE marketing resources from Emma's website, well worth checking them out.https://pearcemarketing.co.uk/free-marketing-advice/Your Business Hour podcast is hosted by the founders of Champ Consultants, Chantal and Matthew Baker. They are both accountants and bring a wealth of knowledge, experience, and business tips to their chat. They interview guests who tell their business stories, as well as consider the latest topics in business and finance.New podcasts are released weekly on a Tuesday and you can follow us on:Instagram: @your.businesshourFacebook: @your.businesshour
Kate Fox's business is Fox Graphics Design & Marketing, which she started in 2008 as a single mum whose clients range from sole traders to multi-national companies. During our chat with Kate she shared some branding tips and how these can be used to grow your business, tips to start ups in starting a business and much more. On her website Kate has a downloadable – ‘5 things you need to know in order to answer the Big Marketing question. You can find Kate at https://foxgraphicsdesign.com/Your Business Hour podcast is hosted by the founders of Champ Consultants, Chantal and Matthew Baker. They are both accountants and bring a wealth of knowledge, experience, and business tips to their chat. They interview guests who tell their business stories, as well as consider the latest topics in business and finance.New podcasts are released weekly on a Tuesday and you can follow us on:Instagram: @your.businesshourFacebook: @your.businesshour
Sally Cranham is a commercial utilities consultant and premier introducer with Full Power Utilities allowing businesses to save money and improve cash flow. Sally offers business owners guidance, advice and cost savings when it comes to their utility expenses.When Sally isn't saving people time and money on their bills and general utility admin she works in freelance copywriting and marketing for a company in Kent, runs an Airbnb, and sings professionally with bans and as a solo act.You can find Sally at https://currentutilities.co.uk/Your Business Hour podcast is hosted by the founders of Champ Consultants, Chantal and Matthew Baker. They are both accountants and bring a wealth of knowledge, experience, and business tips to their chat. They interview guests who tell their business stories, as well as consider the latest topics in business and finance.New podcasts are released weekly on a Tuesday and you can follow us on:Instagram: @your.businesshourFacebook: @your.businesshour
Mags Bell in an international speaker, executive gemologist, author of ‘What the Bleep is coaching?', awareness expert and the creator of LeadingMe® Mags Bell. Mags explains to us how to align your inner critic in order for you to bring out your brilliance and so you can go on to create powerful results in your industry. You can find out more about Mags at https://magsbell.com/blog/You can find out more about Mags book at : https://bit.ly/Book_WhatTheBleepIsCoachingAlso, get your FREE gift - FREE webinar http://bit.ly/SilencingYourInnerCriticWebinar1 Your Business Hour podcast is hosted by the founders of Champ Consultants, Chantal and Matthew Baker. They are both accountants and bring a wealth of knowledge, experience, and business tips to their chat. They interview guests who tell their business stories, as well as consider the latest topics in business and finance.New podcasts are released weekly on a Tuesday and you can follow us on:Instagram: @your.businesshourFacebook: @your.businesshour
On this episode of 2WL, we have one of Steve DeNovi's best friends, Matthew Baker on the show and we discuss their days at Gold's gym, some verification on the infamous commercial gym stories, some of Steve's odd quirks, the growth of Steve's coaching, and a test on who knows Steve the best.
This hour featured Tyler & Will playing start, bench, cut with engineer Matthew Baker and Producer Ben.See omnystudio.com/listener for privacy information.
This hour featured Tyler & Will playing start, bench, cut with engineer Matthew Baker and Producer Ben.See omnystudio.com/listener for privacy information.
This hour featured Tyler & Will playing start, bench, cut with engineer Matthew Baker and Producer Ben.See omnystudio.com/listener for privacy information.
On October 27, 2016 in Henry County Georgia, four people were killed during a bonfire party. Two men were indicted and charged with murder. One confessed to the murders and told officers that he was solely responsible. Authorities charged the other man with murder anyway and placed him in jail. In 2021, this man was re-indicted on 30 charges, and the state is seeking the death penalty. He still awaits trial 7 years after the killings. Get bonus content from Generation Why at: patreon.com/generationwhyListen ad free with Wondery+. Join Wondery+ for exclusives, binges, early access, and ad free listening. Available in the Wondery App. https://wondery.app.link/generationwhy.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Sky Sports F1's Naomi Schiff, Martin Brundle and Simon Lazenby join Matthew Baker to preview the Sky Original film: 'Ferrari', which tells the story of the team's founder, Enzo, featuring actors Adam Driver, Penelope Cruz, Patrick Dempsey, directed by Michael Mann.'Ferrari,' a Sky Original film, in cinemas from Boxing Day in the UK&I, and available in cinemas around the world throughout December.
A teacher's quest to investigate a horrific murder leads Hannah Stein and her students into an adventure and shadows of her past in "The Class Assignment is Murder." Author Carolyn Kleinman draws on her own life and experiences as a teacher to bring this, her second novel for Sunbury Press Books. Hannah discovers her move to Parkerville, a small town in Lancaster County, Pennsylvania is not the idyllic place everyone says it is. She discovers that in 2005, a teenage boy named Matthew Baker murdered his family and raped his cousin. Fifteen years later, Matthew now says he is innocent. Hannah enlists the aid of three of her students to investigate the Baker case and dredges up a past that some do not want disturbed. For Hannah, the assignment brings up her own past, having witnessed her mother's murder at the age of five (but did not see her attacker's) face. Carolyn Kleinman grew up in the Twin Cities and earned Bachelor's and Master's degrees from the University of Minnesota. She has taught English and English as a Second Language, and is also the author of "Love, Faith and the Dented Bullet." She discusses with host Lawrence Knorr what drew her to create her own stories, and how drew upon true crime and incidents for her works. She lives with her husband Steven in Lancaster, PA.
Menù del giorno: - THE BEAR 2 - ON WRITING di Stephen King (con Santamatita) 1' 35'' - PERCHE' L'AMERICA di Matthew Baker (con Mattia Mariotti) + 7 di Tristan Garcia 18' 43'' - 3 CERTEZZE + 3 SCOMMESSE + 1 LIMBO PER L'ASTA DEL FANTACALCIO 2023-24 (con Angelo Taglieri) 37' 07'' - Lista dell'attesa 64 (The Changeling, Un'estate fa, Sono una testa di Panda) 48' 03'' ATTENZIONE: contiene anche riferimenti a Lost, Lundini, Black Mirror e Tommy Baldanzi. LINK: - Il mondo di Yugen Podcast - Il mondo di Santamatita - Generazione fantacalcio di Angelo Taglieri ELENCO BONUS: I consigli di lettura di Stephen King per aiutare a rispettare la Regola Principe dello scrivere molto e leggere molto: Peter Abrahams: A Perfect Crime - Lights Out - Gli abissi dell'amore - Revolution #9 James Agee: Una morte in famiglia Kirsten Bakis: Lives of the Monster Dogs Pat Barker: Rigenerazione - L'occhio nella porta - The Ghost Road Richard Bausch: In the Night Season Peter Blauner: L'intruso Paul Bowles: Il cielo che ripara T. Coraghessan Boyle: America Bill Bryson: Una passeggiata nei boschi Christopher Buckley: Si prega di fumare Raymond Carver: Da dove sto chiamando Michael Chabon: Lupi mannari americani Windsor Chorlton: Latitude Zero Michael Connelly: Il poeta Joseph Conrad: Cuore di tenebra K.C. Constantine: Don DeLillo: Underworld Nelson DeMille: Cattedrale - La costa d'oro Charles Dickens: Oliver Twist Stephen Dobyns: Common Carnage - Il santuario delle ragazze morte Roddy Doyle: La donna che sbatteva le porte Stanley Elkin: The Dick Gibson Show William Faulkner: Mentre morivo Alex Garland: L'ultima spiaggia Elizabeth George: Il prezzo dell'inganno Tess Gerritsen: Forza di gravità William Golding: Il signore delle mosche Muriel Gray: Furnace Graham Greene: Una pistola in vendita - Il nostro agente all'Avana David Halberstam: The Fifties Pete Hamill: Why Sinatra Matters Thomas Harris: Hannibal Kent Haruf: Canto della pianura Peter Høeg: Il senso di Smilla per la neve Stephen Hunter: Dirty white boys - Cattivi ragazzi David Ignatius: L'amico della spia John Irving: Vedova per un anno Graham Joyce: The Tooth Fairy Alan Judd: Scrittura infernale Roger Khan: Good Enough to Dream Mary Karr: Il club dei bugiardi ( Jack Ketchum: Right of Life Tabitha King: Survivor - The Sky in the Water Barbara Kingsolver: Gli occhi negli alberi Jon Krakauer: Aria sottile Harper Lee: Il buio oltre la siepe Bernard Lefkowitz: Our Guys Bentley Little: The Ignored Norman Maclean: In mezzo scorre il fiume William Somerset Maugham: La luna e sei soldi Cormac McCarthy: Città della pianura - Oltre il confine Frank McCourt: Le ceneri di Angela Alice McDermott: Il nostro caro Billy Jack McDevitt: Ancient Shores Ian McEwan: L'amore fatale - Il giardino di cemento Larry McMurtry: Dead Man's Walk Larry McMurtry e Diana Ossana: Zeke and Ned Walter M. Miller: Un cantico per Leibowitz Joyce Carol Oates: Zombie Tim O'Brien: Il mistero del lago Stewart O'Nan: Mi chiamavano Speed Queen Michael Ondaatje: Il paziente inglese Richard North Patterson: Nessun luogo è sicuro Richard Price: Freedomland Annie Proulx: Distanza ravvicinata - Avviso ai naviganti Anna Quindlen: Una figlia esemplare Ruth Rendell: A Sight for Sore Eyes Frank M. Robinson: Waiting J. K. Rowling: Harry Potter e la pietra filosofale - Harry Potter e la camera dei segreti - Harry Potter e il prigioniero di Azkaban Richard Russo: Mohawk John Burnham Schwartz: Reservation Road Vikram Seth: Il ragazzo giusto
Osteoarthritis (OA) is the most common form of arthritis. There are currently no effective disease-modifying treatments available to slow or reverse the progression of OA. Drugs such as metformin, which is commonly used to treat type 2 diabetes are generally safe and low cost. Research has been shown that metformin has anti-inflammatory and pro-weight loss effects, suggesting that the use of metformin may be useful in the treatment or prevention of OA. Dr Matthew Baker joins us on this week's episode of Joint Action to discuss this important topic. Dr. Matthew Baker is the Clinical Chief in the Division of Immunology and Rheumatology at Stanford University. He received his bachelor's degree from Pomona College, his medical degree from Harvard Medical School, and his master's degree in Epidemiology and Clinical Research from Stanford University. He completed his Internal Medicine residency at the Massachusetts General Hospital and his Rheumatology fellowship at Stanford University. Dr. Baker has established a clinical research program that is focused on clinical trials, epidemiological studies, and bench-to-bedside translational research. He has designed and led investigator-initiated and industry sponsored clinical trials with a focus on sarcoidosis, IgG4-related disease, and rheumatoid arthritis. In addition, he is the Co-Director of the Stanford Multidisciplinary Sarcoidosis Program and collaborates with other team members to advance sarcoidosis clinical care and research.RESOURCESDevelopment of Osteoarthritis in Adults With Type 2 Diabetes Treated With Metformin vs a SulfonylureaIncreased risk of osteoarthritis in patients with atopic diseaseCONNECT WITH USTwitter: @ProfDavidHunter @jointactionorgEmail: hello@jointaction.infoWebsite: www.jointaction.info/podcastIf you enjoyed this episode, don't forget to subscribe to learn more about osteoarthritis from the world's leading experts! And please let us know what you thought by leaving us a review! Hosted on Acast. See acast.com/privacy for more information.
Today's Lead Lap with Sam Forman & Matthew Baker featured, NASCAR at Kansas & F1 Miami GP Previews, Legacy Motor Club moving to Toyota, RCR's No.3 teams penalties being upheld and more. See omnystudio.com/listener for privacy information.
Today's Lead Lap with Sam Forman & Matthew Baker featured a recap of NASCAR at Dover, Chris Bernard recaps IndyCar & F1, Ryan Truex's 1st Xfinity Series win, Martin Truex's Jr snapping a 54 race winless streak and soundbites from a number of NASCAR drivers. See omnystudio.com/listener for privacy information.
Join Prof Iain McInnes as he reviews two interesting papers that help to broaden our understanding and knowledge on the safety of biologic and targeted synthetic DMARDs. In the first of today's papers, Matthew Baker and colleagues determine the risk of developing interstitial lung disease (ILD) in patients with RA, undergoing treatment with different biologic and targeted synthetic DMARDs. In the second paper, Lars Kristensen and team analyse data from ORAL Surveillance to help identify subpopulations with different relative risk (i.e., 'high-risk' and 'low-risk') with tofacitinib versus TNFi. To access detailed summary slides of the papers discussed today, visit cytokinesignalling.com.
In which Matthew Baker cherishes corporeal existence.
Sarc Fighter: Living with Sarcoidosis and other rare diseases
Angelica Gauptman's grandmother died from complications of sarcoidosis. Angelica is trying to figure out why. She believes it had something do with the combination of Vitamin D and Prednisone. To be clear there is no clinical evidence that proves a link. Angelica is a high school senior with more than your average get up and go. She has undertaken a survey of Sarc patients, and has gotten the attention of some top level researchers. Hear her story, and the heartbreaking way her grandmother passed in this edition of the Sarc Fighter Podcast. Show Notes Learn about the clinical trial from Novartis: https://bit.ly/3o9LXKk email Angelica agauptman@gmail.com Remember these hashtags for April! #WhatIsSarcoidosis #MakeItVisible Here is a link to all the activities for April ! https://www.stopsarcoidosis.org/awareness-2022 Universal Barriers Podcast: https://www.stopsarcoidosis.org/sarc-fighter-podcast/ More on Universal Barriers https://www.stopsarcoidosis.org/events/universal-barriers-in-dealing-with-a-chronic-disease-a-sarcoidosis-perspective/ Ignore No More https://www.stopsarcoidosis.org/ignore-no-more-foundation-for-sarcoidosis-research-launches-african-american-women-sarcoidosis-campaign/ Sarcoidosis Awareness Film: https://www.purpledocumentary.com/ Nourish by Lindsey: https://www.nourishbylindsey.com/ Dr. Jinny Tavee's book, The Last Day of Suffering: https://www.amazon.com/Last-Day-Suffering-Health-Happiness/dp/0615542751 Read about the patient trial with aTyr 1923 https://investors.atyrpharma.com/news-releases/news-release-details/atyr-pharma-announces-positive-data-phase-1b2a-clinical-trial Also -- Note that investors also believe in the promise of aTyr 1923: https://investors.atyrpharma.com/news-releases/news-release-details/atyr-pharma-announces-closing-863-million-public-offering Yale University and sarcoidosis skin treatment | Dr. William Damsky: https://news.yale.edu/2018/12/26/yale-experts-treat-severe-disfiguring-sarcoidosis-novel-therapy Stanford University Clinical trial | Dr. Mathew Baker: https://med.stanford.edu/sarcoidosis/clinical-trial.html Bonus Episode on COVID-19 and Sarcoidosis https://beatsarc.podbean.com/e/bonus-episode-sarcoidosis-and-covid-19-presented-by-the-foundation-for-sarcoidosis-research/ Bonus Episode Sarcoidosis and Prednisone: https://beatsarc.podbean.com/e/bonus-episode-sarcoidosis-town-hall-dealing-with-prednisone-presented-by-the-foundation-for-sarcoidosis-research/ MORE FROM JOHN Cycling with Sarcoidosis http://carlinthecyclist.com/category/cycling-with-sarcoidosis/ Watch the Prednisone Town Hall on YouTube https://youtu.be/dNwbcBIyQhE More on aTyr Pharma: https://www.atyrpharma.com/ Do you like the official song for the Sarc Fighter podcast? It's also an FSR fundraiser! If you would like to donate in honor of Mark Steier and the song, Zombie, Here is a link to his KISS account. (Kick In to Stop Sarcoidosis) 100-percent of the money goes to the Foundation. https://stopsarcoidosis.rallybound.org/MarkSteier The Foundation for Sarcoidosis Research https://www.stopsarcoidosis.org/ Donate to my KISS (Kick In to Stop Sarcoidosis) fund for FSR https://stopsarcoidosis.rallybound.org/JohnCarlinVsSarcoidosis?fbclid=IwAR1g2ap1i1NCp6bQOYEFwOELdNEeclFmmLLcQQOQX_Awub1oe9bcEjK9P1E My story on Television https://www.stopsarcoidosis.org/news-anchor-sarcoidosis/ email me carlinagency@gmail.com Remember these hashtags for April! #WhatIsSarcoidosis #MakeItVisible Here is a link to all the activities for April ! https://www.stopsarcoidosis.org/awareness-2022 Learn about the clinical trial from Novartis: https://bit.ly/3o9LXKk Universal Barriers Podcast: https://www.stopsarcoidosis.org/sarc-fighter-podcast/ More on Universal Barriers https://www.stopsarcoidosis.org/events/universal-barriers-in-dealing-with-a-chronic-disease-a-sarcoidosis-perspective/ Ignore No More https://www.stopsarcoidosis.org/ignore-no-more-foundation-for-sarcoidosis-research-launches-african-american-women-sarcoidosis-campaign/ Sarcoidosis Awareness Film: https://www.purpledocumentary.com/ Nourish by Lindsey: https://www.nourishbylindsey.com/ Dr. Jinny Tavee's book, The Last Day of Suffering: https://www.amazon.com/Last-Day-Suffering-Health-Happiness/dp/0615542751 Read about the patient trial with aTyr 1923 https://investors.atyrpharma.com/news-releases/news-release-details/atyr-pharma-announces-positive-data-phase-1b2a-clinical-trial Also -- Note that investors also believe in the promise of aTyr 1923: https://investors.atyrpharma.com/news-releases/news-release-details/atyr-pharma-announces-closing-863-million-public-offering Yale University and sarcoidosis skin treatment | Dr. William Damsky: https://news.yale.edu/2018/12/26/yale-experts-treat-severe-disfiguring-sarcoidosis-novel-therapy Stanford University Clinical trial | Dr. Mathew Baker: https://med.stanford.edu/sarcoidosis/clinical-trial.html Bonus Episode on COVID-19 and Sarcoidosis https://beatsarc.podbean.com/e/bonus-episode-sarcoidosis-and-covid-19-presented-by-the-foundation-for-sarcoidosis-research/ Bonus Episode Sarcoidosis and Prednisone: https://beatsarc.podbean.com/e/bonus-episode-sarcoidosis-town-hall-dealing-with-prednisone-presented-by-the-foundation-for-sarcoidosis-research/ MORE FROM JOHN Cycling with Sarcoidosis http://carlinthecyclist.com/category/cycling-with-sarcoidosis/ Watch the Prednisone Town Hall on YouTube https://youtu.be/dNwbcBIyQhE More on aTyr Pharma: https://www.atyrpharma.com/ Do you like the official song for the Sarc Fighter podcast? It's also an FSR fundraiser! If you would like to donate in honor of Mark Steier and the song, Zombie, Here is a link to his KISS account. (Kick In to Stop Sarcoidosis) 100-percent of the money goes to the Foundation. https://stopsarcoidosis.rallybound.org/MarkSteier The Foundation for Sarcoidosis Research https://www.stopsarcoidosis.org/ Donate to my KISS (Kick In to Stop Sarcoidosis) fund for FSR https://stopsarcoidosis.rallybound.org/JohnCarlinVsSarcoidosis?fbclid=IwAR1g2ap1i1NCp6bQOYEFwOELdNEeclFmmLLcQQOQX_Awub1oe9bcEjK9P1E My story on Television https://www.stopsarcoidosis.org/news-anchor-sarcoidosis/ email me carlinagency@gmail.com The following is a web generated transcript from my interview with Angelica Gauptman.I'm sorry for typos and misspellings. Welcome back to the Sarc Fighter podcast. And joining me now is Angelica Galtman • • in California. Angelica, welcome. You're just across the bridge from San Francisco. Yes. Thank you. I am. Yes. All right. So that you are in Marin County, and you were just telling me that, it's often foggy in San Francisco, but it's always beautiful in Marin County. Yes. As soon as you kind of cross the middle of the Golden Gate Bridge, it's like a wall. • • It's kind of like the Marinas, the heavens, and San Francisco the opposite. It's very funny. Always very funny to drive across the bridge. Got it. Okay. Well, now, um, you are a high school student applying, to colleges. But we were just talking before we began recording. You are looking to go to some fairly impressive colleges. Where have you applied? I've applied to a lot of the IVs, Stanford, Harvard, UPenn, Columbia, um, and a lot of the UCS. UCLA is definitely my top choice. So, yeah, I guess they are, um, • pretty hard to get into, but we'll see. Yeah, well, those are high levels, but • • you obviously have the grades in the background and so forth to handle that sort of thing. Possibly. I don't know what they're looking for, so I have no idea, but hopefully something will get me there. Let's talk a little bit about your sarcoidosis story. And when I say yours, I mean your grandmother's. So your grandmother died from complications related to sarcoidosis. Is that the best way to put it? Yes, I'd say so, yeah. All right. And you are trying to figure out if there's a connection between prednisone and vitamin • • • D, • which, um, could be very controversial. There are so many places to start here, but let's just jump in with your grandmother's story. Um, when was she diagnosed with prednisone? Um, two, 2007. She was diagnosed with pulmonary circuit two, 2007 and then pregnant on, I believe, in two 2009. Okay. And she took prednisone for quite a long time. Up until two 2017. Okay. Did she pass IN 2017? 20 17. Took it all the way through? Yeah, all the way through. Do you know what levels of, uh, doses she was • • • taking? Do you know what I think it was? Two 200, but I will need to • • • • check. Wow. Okay. That would be a lot. Yes. She was on a lot of it. A lot of PREDNISONE. All right, so she was also taking was she prescribed vitamin D or did she just take vitamin D? Um, at the time, they were prescribing her vitamin D supplements. But now that I look into her case • • file, she, um, was over producing vitamin D naturally, as a lot of pulmonary circulations patients do. It just didn't come up on the scans because the vitamin D that she was producing was actually in an inactive • • state. So it didn't come up on the scans that they did. They had to do a scan for inactive vitamin D to find it, but they didn't do that. So they just prescribed her more vitamin D supplements instead of doing the second • • scan. Got it. And what eventually led to her death, according to your hypothesis • • • then? • • • • So, • • • • um, I think that the overabundance of vitamin D that was in her system, • • • um, um, with the over, like, immense amount of predisone that she was • • taking led to the hemorrhage that she had. So the hemorrhage was an, um, internal bleeding. It was a really big part of it. A, um, really big bruise on her abdomen. And she developed that about a week or • • • • so after, um, they up her credit zone a little • • bit because they had been taking it down slowly. But they upped it again. And once they upped it, she, um, kind of developed that bruise. And that's what we went to the hospital • • for. And, uh, that's what led to, um, her kidney failure and her untimely death. Um, so I believe that the prednisone and vitamin D are what caused the hemorrhage or the bruise. And that's what caused her to pass away. Now you're taking a course where you look into correlations, causations, that sort of thing. What is it? It's AP research. And so you started looking at other patients to • • see if your grandmother was not the only one. Tell us why you thought that and what you found. So, um, in the class, we are taught to, uh, create our own project. And it was supposed to be a gap in the knowledge that is there today. And so this, to me was a gap in the knowledge because nobody. I talked to researchers at Stanford, UCSF that had, um, been researching, especially pulmonary circuit oysters for years. And they had never come across or thought of anything like this. And there were no real scholarly articles out there about this or scholarly work. So this, um, was my gap. And in the class we're supposed to create our own methodology and collect our own data. So I thought that there was no better way since there was no data on this out there, there was no better way than to • • • interview other patients to see if • • • they had similar experiences with prednisone or vitamin D. And, um, so when I talked to quite, um, a few, they had told me that they never developed hemorrhage, uh, that large bruise on their abdomen. However, they told me that they also were over prescribed vitamin • • • D because again, the doctors and researchers didn't do that second scan for the inactive form of vitamin D. And they said that when they were taking vitamin D and prednisone, there were a lot of detrimental, • • • • um, effects on their bodies that they experienced. And one man actually told me that he did start to • • • • • ease very easily when they upped his Joseph prednisone while he was on vitamin • • • • D, which didn't happen when he was off of vitamin • • • D. Interesting. So he was continuing to take the • • pretinosome, which, most of us do. I think that's for ninety 90% of patients, that's the first line of defense is prednisone. So almost everybody listening to this, if they have had • sarcodosis, has, taken prednisone. But the vitamin, uh, D is the wildcard here. And so you found at least one other person. How many patients have you • • • • • interviewed? So, um, through FSR, I interviewed • four. And, um, then outside of FSR, on my own findings, I interviewed about ten to fourteen. Okay, all right, got it. And these patients were • • • all were they taking vitamin D because they were in the supermarket and they said, oh, I'm going to take vitamins. Vitamin D is good for you. Or were they prescribed vitamin • • D? No. Every single one of them was prescribed a vitamin D supplements, except for the very few of them, • um, whose doctors actually thought to do the scan for inactive vitamin D and saw the circuit patients overproduce it naturally. So, aside from the two that were taken off the supplements because of that second scan, everybody was prescribed vitamin D • • supplements. Got it. So are you still actively looking for people to • • interview? I am, yes. So, • • um, while my project itself is due in the next month for the class, I will definitely be continuing to research myself. So, yeah, I'm definitely looking, um, for more interviewees. Yeah. Okay. So what kind of person was your • • • • grandmother? My grandmother was amazing. She was just the best person. She was my best friend, really, • truly. She, uh, was the one who kind of. My parents were both at, um, work • • very most of the day. So she was the one who I kind of spent most of my time with when I was, um, • • little. And, um, when I grew • • • • • • up, • • um, she was honestly an incredible woman. She taught me to Cook, she taught me manners. She taught me everything honestly. And, um, while the disease definitely slowed her down, she had oxygen tanks that she was trapped to and she couldn't really • • travel. Even though, um, she loved to travel, she, um, still somehow • • always helped me with whatever I needed. She always was there for me. Whenever I had an event at school, she would always help me with those. • • • • So she • • was so absolutely selfless. It was honestly inspiring to me. That's an amazing story. And then, when did she first start noticing that there was something • • • • • • wrong? When I was about • five. I, um, don't even remember what she noticed. If I'm being honest, I think I was too young to notice. And when she passed, I was only thirteen. Well, um, it's been a long time, so I don't really know what caught how she noticed it, but I just • • remember, I, um, was sitting on the couch when I was five and there was a man that came with oxygen tanks into our house at about seven or eight. 08:00 p.m. It was late for me back • • then, and, um, he strapped her to the oxygen tanks or strapped them onto her, I guess so. That's just what I • • • remember. I remember she had a lot of trouble breathing. That's what I remember it to • • • • • be, ultimately, because it's very hard in many, um, cases for doctors to even diagnose • • sarcoidosis. So I was just wondering if you, um, knew anything about • • how that all came. So, um, they didn't really know what it was back then as well, as much. It was even less research than it is now. And at that time, she was in her late fifty 50s and told her that she was one of the really rare people and that, um, this illness only traveled • • within very young women, which now we see is not true at all. But so, um, yeah, at the • • time, they didn't expect • • it. They, um, thought it was actually literally anything • • • else, but, um. Yeah, so that's what they kind of told her. They said that you're one of the rare women that isn't in her twenty 20s or 30s that got • • • • this interesting. Wow. So she lived with you're, spending most of your time with her, your parents are at work and she's got these oxygen tanks. What was her daily life. Like? It was very selfless. Again, I don't know how to describe • • • it. She was on bedrest, sadly, for most of the last few • • • years. • • Um, it was very hard for her. The oxygen tanks and the absolute lack of energy that she had and the lack of mobility that she • • had. So, um, her life was mostly just taking care of me and my little cousins. I have three little cousins who are all boys, who at the time lived with her as • • well. And, um, so she would take care of us all the time. She would Cook for the whole • family. So her daily life was just taking care of others. Always. It was always helping my little cousins with their homework, helping me with my homework, cooking for us, cleaning the • • house. So, um, it was selfless, very selfless. But she was able to do that even with the sarcoidosis. Uh, did she have the oxygen tanks that you pulled on a little cart or how did she get Around? Um, well, the oxygen tanks were on wheels, so she could walk and kind of stroll them. But cooking wise, uh, she kind of just stood and seared it on the pan and put it in the oven. And then for all of our homework, we would be usually sitting for that and then cleaning wise. I mean, she didn't mop the floors or anything like that, but she'd, like, clean up the dishes or something that required standing and moving her arms instead of running around the house. And she just continued to do that right on through Sarcaidosis. Oh, • • • • yes. Wow. What was your grandmother's name? Lydia Glaser. It must have been very sad for you and your family when you took her to the hospital because of what looked like a bruise. And then she didn't come home. Yeah, it was shocking. And, um, there were definitely aspects of, • • um. Um, I guess layers of shock that came in as well, because it was really interesting. She had • • actually been doing, um, a lot better on the last two days before her passing, then her entire week • that she spent there, and they had actually signed her out of the ICU and put • • • her into, um, normal hospital room. And she would be fine to go over the night. So, um, in the morning, they said that she would be free to go. And then that morning, her kidneys started shutting down. And so, • • • um, that was the shocking, um, part, I think it was. Two days later, she passed away. Um, and again, the kidneys were also another kind of thing in my research that I looked at as well, because, um, of kind of the connection of vitamin D and prednisone and all that. So all of it, her whole case, honestly, is just such a • mystery. And I'm trying, um, so hard to kind of connect the dots, but it's very hard, as you can • • • imagine. • • • Wow. So you reached out to the foundation for sarcoidosis research. Did you just find them with a Google search or how did that come to be? Yes. So I believe, um, it was my sophomore year of high school. I'm a senior now, so two years • • • ago, • •um, I don't know. I felt like I was old enough to kind of • • • start researching and looking into her case file and all that • • stuff. But, • • • um, before I even began or thought of my • research, I just wanted, um, to do something that would contribute to the community that my grandmother was in, and that would kind of, I don't know, not honor her, • • but, yeah, I guess it is honor her in a way, because I just saw how she was such an active person. She loved to travel before Circuit Oasis, and now she couldn't. And I couldn't imagine a whole community, um, of people going through that. • So not only in, um, her name, but also for the community. I just kind • • of reached, um, out. I asked for an internship, but I was sixteen 16 and would, uh, only give out internships to eighteen 18 • • or. And so they, um, actually had to redo. I feel terrible for Mindy. They had to redo their entire paperwork to allow me to intern and volunteer at the age of • • • sixteen 16. And I got put with Jim and his peer mentor team • • and. Yeah, it just kind of took off from • • there. Wow. How old are you now? Are you eighteen? I'm eighteen 18. Yeah. Eighteen 18 now. Okay, so you've been doing this for two years? Yes. And will you continue, uh, to work with FSR? Definitely. I'm trying to start a youth advocacy program at my high school where I've been trying, um. It's getting very close. • • • • Um, I have a lot of ideas for FSR, and, uh, I also just love working with everybody in the gym. It's a great community that I love being a part • • • • of. • • • • • Wow. • Um, and so when will you feel like you have a sample size • • • or enough, uh, data to move, uh, • • forward with • • your project or feel like it's Done? I don't think I'll ever feel like it's done if I'm being honest. I think I want to keep pursuing this until I get a solid answer or until I start testing it in the lab or something like that. So I don't think my hypothesis is enough for me. And I don't think gathering enough evidence to support it is enough for me. I think I want to actually see the evidence to have, um, it kind of be enough and then see how we can. I mean, if it's true and if it's plausible to • • see how I can keep, um, helping and seeing if maybe people should start testing for this inactive form of vitamin D and seeing how I can kind of make that happen. So I don't think that it's honestly ever going to be done for me. This project. Um, even with hypothesis, that's definitely not what I'm ending with now. You will know soon if you've been accepted to Harvard or one of these other places. Are you going to be a medical student? Because you told me that you also might look at being a lawyer. I can't imagine you having the time to study for the bar exam and doing this. Yeah. So it really depends. I'm just so unsure of my major right now. I have two very different kind of spheres and majors that I could go into right now. I've been working at a law firm for the past couple of years. I really like that sphere, um, of work as well. But even if I were to go into law, I think that I would still continue this with what time I had and maybe pass it on to somebody else and just kind of help out as much as I could. But I definitely don't want this project and this hypothesis to kind of • • • end because I think it is, um, so important. So if I do study, end up researching medicine in College, um, and have that be my major truth, this is definitely going to be my preferred project. But if it's lost, then either I'll pass it onto someone or just continue it on my downtime. Yeah. So have you gotten any sort of interest, uh, from researchers that are already out there in the field, that have been through all of this and are looking for • • something to dive more deeply • • • into? So I've run this by, um, the two researchers that I think would be most interested in right now or have given me the most interest. • • Um, one young man, uh, at Stanford, Dr. Matthew Baker, he showed a lot of interest in this. He's helped me with, the abstract of my paper and my hypothesis. And then Dr. Laura Copp at UCSF, uh, has also kind of responded and given me • • some feedback. So, I think it's kind of • • also, I can't imagine being a researcher and • • having all of these medical students with me and then • • having a high school student trying to call me and say, • • hey, here's what I've been • • • doing. Why don't you take me • • on? So I, um, don't know. I can't imagine really that happening for me now, but it's shocking that I've gotten so much feedback from all these researchers. And although these responses from them so far, those two have been the most promising. But I definitely want to start trying to get into labs and things like that, which maybe would be possible with Stanford, um, sooner or later. So you do realize how otherworldly this sounds - high school student calls and says, I need you to look into this. And here's what I think. And I've already interviewed people, and that just doesn't happen every day. Yeah, I know. It's silly. I feel silly talking about it if I'm being honest, because I don't know, I can't really take myself seriously. So I can't imagine all of these people with MDS and PhDs and who've been working and researching for so long looked like taking me seriously, which is completely fair. But somehow I've been getting all these responses. So I guess something must be working or they just find me to be funny. I don't know. But you have a real story with your grandmother, and you obviously have, uh, a drive and a passion, and you've gone about it the right way by going through the foundation, for sure. And if you've got Mindy and Jim Kuhn on your side, um, those people, uh, when they speak, people listen. You're doing it the right • • way. Hopefully. Yeah, hopefully. We'll see. Hopefully this takes off somehow. All right, so you and I are speaking right now. On the ten 10 March in 2022 and very comfortably, um, ten, 1030 in the, uh, my time. And you are up at what, seven, 730? Yes, 730. And about to go to • • • school? Sadly, • • yes. So where do you go to school? Redwood High School in Larksburg, California. Um, Redwood high School. And you're taking AP • • • • classes? Well, not a lot. Three. So when you get to College, how many College credits will you already • • have? More than I need. So I think I would have a semester, uh, done already. It depends how many classes I take there. Right. And if you get into, say, Harvard, they'll accept all of your AP credits. You • hope. I hope my AP exams should allow for • • • • • that, um, to be a realistic thing, but I'm not sure because some of the classes AP research. I don't think there is a College credit for • • it. But we'll see. I don't know. It depends on every school takes different credits, but hopefully they'll take all of my credits. Yeah, • • well, and are you taking a lot of chemistry? Uh, and so forth and so • on? Biology. I love biology. Biology. Physiology. Tech. Chemistry. I took last year. It's very interesting, but for some reason, physiology and biology is really my thing. I really love that. Okay. But you said, sadly, you're going to school today or are you just over it? Yes. Senioritis is kicking in. I'm not sure if you're familiar with the term, but it's really big over here. I'm, um, done. I'm ready. I'm ready for the • summer. Yeah, we had that term even back when I was in high school. In the dark ages. Yeah. All right. So if somebody wants to reach out to you, if they listen to this and they want to be interviewed or they want to share a story. How do they do • • • • it? Well, they can email, um, me or they can. I mean, I have social media. Um, that's also a thing, but, um, they could also reach me through Mindy or, uh, Jim as well. They all have my, um, contact information. But John, I can leave, um, my email with you as well. Okay, let's do that. And I'll just put it in the show notes and then people can just click on that and send you an email. And I don't think you'll, um, be covered up with people, but hopefully somebody listening to this will say, wow, this young lady is on to something. And let's give her the opportunity, uh, to succeed. Hopefully. Okay. Angelica, thank you so much for your time this morning.