State of prolonged public dispute or debate
After Netflix released its latest Dave Chappelle special earlier this month, the company faced strong criticism from the transgender community and its own employees. WSJ's Joe Flint explains how the controversy has challenged Netflix's culture of 'radical candor' and we go on the ground at the Netflix employee walkout. Learn more about your ad choices. Visit megaphone.fm/adchoices
A day late but certainly not a dollar short! The team is ready and raring to talk the stories of the week | TV Blackbox S06E14 It was the week channel 10 showcased its 2022 slate while Lisa Wilkinson's publicity campaign for her new book hit a snag… and news leaked about the All Stars Big Brother Cast. In this episode:· 1.45 – 10 Upfront – The New Shows· 9.09 – 10 swings the axe· 11.35 – Lisa Wilkinson faces a backlash over claims in her new book· 16.15 – Nine's new NRL deal· 19.15 – Ratings Wrap· 28.07 – Big Brother All Stars cast revealed· 31.14 – The BBC names the top 100 shows of the 21st century· 34.28 – Hatches & Dispatches· 35.49 – TV BingeboxSupport this show http://supporter.acast.com/tv-blackbox. See acast.com/privacy for privacy and opt-out information.
This week the boys discuss the controversy of Jon Gruden and the Washington Football Team and Dave Chappell's new Netflix special. They talk about the difference in discipline between the black and LGBTQ+ community. Please be sure to like, comment, and subscribe for weekly content. Be sure to follow us on Instagram and Twitter @DNAPodcastCLT. We are also on YouTube at Dee N Antonio Podcast.
Controversy alert. In this episode, the dads have some upheaval as they break down "How Fathers Can Avoid Pitfalls of Shifting Parenting Roles According to a Therapist" by John Duffy. Which side of the dad takes will you see? Then in parenting tweets of the week, MK continues his disdain for Halloween Costumes while Mark and CRX double down their love for the holiday. Then the dads try their hand at a Halloween candy quiz brought to us by PBS and a few thought-provoking questions during "Would You Rather." Finally, we'll find out which dad dressed up as the Gilligan and Skipper with his wife and wrap up with things ever so gently in the things that make us smile close.
On this week's show, we have stories of environmental concerns colliding with symbols of cultural importance. We venture to the spot in Italy where marble for Michelangelo's sculptures once came from. Controversy is also stirring on some mountains in Greece, as wind turbines anger locals. And we hear from a journalist who tracked an endangered leopard through war-ravaged territory.
Majority 54 producer Edie Allard joins the show for the first time to discuss the controversial Dave Chappelle comedy special, The Right's reaction to Mayor Pete's parental leave, and - once again - Ivermectin. We want to hear your thoughts about this episode! Join the conversation and leave us a voicemail at 508-687-2589.Today's episode is brought to you by BetterHelp. BetterHelp is secure counseling done online at lower costs than traditional therapy. As a listener, you'll get 10% off your first month by visiting BetterHelp.com/M54. If you've listened for a while, you know that Ravi and Jason would be nothing without their Athletic Greens. See what all the hype is about when you go to AthleticGreens.com/majority and get a free year supply of Vitamin D and 5 free travel packs with your order. Upstart knows you're more than just your credit score. Unlike other lenders, Upstart considers your income and current employment to find you a smarter rate for your loan. Find out how Upstart can lower your monthly payments today when you go to UPSTART.com/MAJORITY54If you want to brush up on a foreign language, or learn a new one altogether, Babbel has you covered. When you purchase a 3-month Babbel subscription, you'll get an additional 3 months for free. That's s6 months for the price of 3. Just go to Babbel.com and use promo code MAJORITY54. Jason is back with a new season and a new co-host, Ravi Gupta. Each week, they'll tackle our most pressing issues, giving you the tools necessary to successfully have conversations across the aisle.Majority54 is a Wonder Media Network production. It's produced by Grace Lynch and Edie Allard. Theme music provided by Kemet Coleman. Special thanks to Diana Kander.Majority 54 on TwitterJason on TwitterJason on InstagramRavi on TwitterRavi on Instagram
Adam and Mark link up in-studio for a mid week Best Hour and they open the show discussing the currently happening walkout of Netflix employees protesting trans rights amid Dave Chappelle's recent special 'The Closer'. Next Mark pivots to Steve Bannon as they discuss his ignoring a subpoena from the January 6th Commission as well as the details surrounding the death of Ashley Babbitt. As the show wraps up they discuss In-N-Out's San Francisco location being shut down over vaccine rules & Gary jumps in with some breaking news in the Brian Laundrie search. Watch this episode on YouTube at YouTube.com/ReasonableDoubtPodcast and subscribe to that channel, the exclusive home of Reasonable Doubt Please Support Our Sponsors: LiveXLive.com Geico.com Masterworks.io LightStream.com/Doubt
Today’s Guests Justin Giboney – The AND Campaign The Ahmaud Arbery trial involving the men who are accused of killing him is moving forward. Carmen and Justin also discuss the continued culture of cancelling, this time involving Dave Chappelle. Duane and Cindy Mullett – Pain to Purpose “From Pain to Purpose: Rediscovering Joy After Suffering a […] The post Depolarizing Religious Freedom and Understanding Chappelle Controversy | Seeing Purpose in Our Pain appeared first on The Reconnect with Carmen | Engaging Culture from a Christian Worldview.
The POP!corn squad heads back to the DC Fandome as we talk about the much-talked about trailers to The Flash, The Batman, and more DC offerings, plus Adele's record-smashing comeback "Easy On Me," Pinoy showbiz chika (Aljur vs. Kylie), and the Kim Seon-Ho controversy that's making its way across the net. Joining Cholo in this episode are Paula Molina, Dren Pavia, and Kristofer Purnell.
Eating leafy greens could help prevent macular degeneration Westmead Institute for Medical Research (Australia), October 13, 2021 A new study has shown that eating vegetable nitrates, found mainly in green leafy vegetables and beetroot, could help reduce your risk of developing early-stage age-related macular degeneration (AMD). Researchers at the Westmead Institute for Medical Research interviewed more than 2,000 Australian adults aged over 49 and followed them over a 15-year period. The research showed that people who ate between 100 to 142 mgs of vegetable nitrates each day had a 35% lower risk of developing early AMD than people who ate less than 69mgs of vegetable nitrates each day. Lead Researcher Associate Professor Bamini Gopinath from the Westmead Institute and the University of Sydney said the link between vegetable nitrates and macular degeneration could have important implications. "This is the first time the effects of dietary nitrates on macular degeneration risk has been measured. "Essentially we found that people who ate 100 to 142 mgs of vegetable nitrates every day had a reduced risk of developing early signs of macular degeneration compared with people who ate fewer nitrates. "If our findings are confirmed, incorporating a range of foods rich in dietary nitrates - like green leafy vegetables and beetroot - could be a simple strategy to reduce the risk of early macular degeneration," Associate Professor Gopinath said. Spinach has approximately 20mg of nitrate per 100g, while beetroot has nearly 15mg of nitrate per 100g. The research did not show any additional benefits for people who exceeded 142mgs of dietary nitrate each day. It also did not show any significant connections between vegetable nitrates and late stage AMD, or between non-vegetable nitrates and AMD risk. One in seven Australians over 50 have some signs of macular degeneration. Age is the strongest known risk factor and the disease is more likely to occur after the age of 50. There is currently no cure for the disease. The research compiled data from the Blue Mountains Eye Study, a benchmark population-based study that started in 1992. It is one of the world's largest epidemiology studies, measuring diet and lifestyle factors against health outcomes and a range of chronic diseases. "Our research aims to understand why eye diseases occur, as well as the genetic and environmental conditions that may threaten vision," Associate Professor Gopinath concluded. Research review shows intermittent fasting works for weight loss, health changes University of Illinois Chicago, October 13, 2021 Intermittent fasting can produce clinically significant weight loss as well as improve metabolic health in individuals with obesity, according to a new study review led by University of Illinois Chicago researchers. "We noted that intermittent fasting is not better than regular dieting; both produce the same amount of weight loss and similar changes in blood pressure, cholesterol and inflammation," said Krista Varady, professor of nutrition at the UIC College of Applied Health Sciences and author of "Cardiometabolic Benefits of Intermittent Fasting." According to the analysis published in the Annual Review of Nutrition, all forms of fasting reviewed produced mild to moderate weight loss, 1 percent to 8 percent from baseline weight, which represents results that are similar to that of more traditional, calorie-restrictive diets. Intermittent fasting regimens may also benefit health by decreasing blood pressure and insulin resistance, and in some cases, cholesterol and triglyceride levels are also lowered. Other health benefits, such as improved appetite regulation and positive changes in the gut microbiome, have also been demonstrated. The review looked at over 25 research studies involving three types of intermittent fasting: Alternate day fasting, which typically involves a feast day alternated with a fast day where 500 calories are consumed in one meal. 5:2 diet, a modified version of alternate day fasting that involves five feast days and two fast days per week. Time-restricted eating, which confines eating to a specified number of hours per day, usually four to 10 hours, with no calorie restrictions during the eating period. Various studies of time-restricted eating show participants with obesity losing an average of 3 percent of their body weight, regardless of the time of the eating window. Studies showed alternate day fasting resulted in weight loss of 3 percent to 8 percent of body weight over three to eight weeks, with results peaking at 12 weeks. Individuals on alternate day fasting typically do not overeat or binge on feast days, which results in mild to moderate weight loss, according to the review. Studies for the 5:2 diet showed similar results to alternate day fasting, which surprised the study's reviewers. The subjects who participate in the 5:2 diet fast much less frequently than alternate-day fasting participants do, but the weight loss results are similar. Weight loss with alternate day and 5:2 fasting are comparable to more traditional daily calorie-restrictive diets. And, both fasting diets showed individuals were able to maintain an average of 7 percent weight loss for a year. "You're fooling your body into eating a little bit less and that's why people are losing weight," Varady said. Varady added the review set out to debunk some myths regarding intermittent fasting. Intermittent fasting does not negatively affect metabolism, nor does it cause disordered eating, according to the studies reviewed. "Fasting people are worried about feeling lethargic and not being able to concentrate. Even though you are not eating, it won't affect your energy," Varady said. "A lot of people experience a boost of energy on fasting days. Don't worry, you won't feel crappy. You may even feel better." The study review includes a summary of practical considerations for those who may want to try intermittent fasting. Among the considerations are: Adjustment time—Side effects such as headaches, dizziness and constipation subside after one to two weeks of fasting. Increased water intake can help alleviate headaches caused by dehydration during this time. Exercise—Moderate to high-intensity endurance or resistance training during food abstention can be done, and some study participants reported having more energy on fast days. However, studies recommend those following alternate day fasting eat their fasting day meal after exercise. Diet during fasting—There are no specific recommendations for food consumption during intermittent fasting, but eating fruits, vegetables and whole grains can help boost fiber intake and help relieve constipation that sometimes accompanies fasting. Alcohol and caffeine—For those using an alternate day or 5:2 fasting plan, alcohol is not recommended on fast days as the limited calories should be used on healthy foods that provide nutrition. There are several groups who should not intermittent fast, according to the studies. Those individuals include: Those who are pregnant or lactating. Children under 12. Those with a history of disordered eating. Those with a body mass index, or BMI, less than 18.5. Shift workers. Studies have shown they may struggle with fasting regimens because of shifting work schedules. Those who need to take medication with food at regimented times. "People love intermittent fasting because it's easy. People need to find diets that they can stick to long term. It's definitely effective for weight loss and it's gained popularity because there are no special foods or apps necessary. You can also combine it with other diets, like Keto," Varady said. Varady has recently been awarded a National Institutes of Health grant to study time-restricted eating for 12 months to see if it works long term. Antioxidants to prevent Alzheimer's disease A balanced intake of antioxidants could prevent the development of Alzheimer's disease. Institut National de la Recherche Scientifique (France), October 13, 2021 Research conducted by the Ph.D student Mohamed Raâfet Ben Khedher and the postdoctoral researcher Mohamed Haddad of the Institut national de la recherche scientifique (INRS) has shown that an oxidation-antioxidant imbalance in the blood is an early indicator of Alzheimer's disease, rather than a consequence. This breakthrough made by researchers under the supervision of the Professor Charles Ramassamy provides an avenue for preventive intervention: the antioxidants intake. The research team showed that oxidative markers, known to be involved in Alzheimer's disease, show an increase up to five years before the onset of the disease. The results of this study, published in the Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring (DADM) journal, suggest that oxidation may be an early marker of this disease that affects more than 500,000 Canadians. “Given that there is an increase in oxidative stress in people who develop the disease, we may regulate the antioxidant systems. For example, we could modulate the antioxidant systems, such as apolipoproteins J and D, which transport lipids and cholesterol in the blood and play an important role in brain function and Alzheimer's disease. Another avenue would be to increase the intake of antioxidants through nutrition”, says Professor Ramassamy. Accessible biomarkers Unlike the current set of invasive and expensive tests used to diagnose Alzheimer's disease, the oxidative markers discovered by Professor Ramassamy's research team can be detected by a blood test. These markers are found in plasma extracellular vesicles, which are pockets released by all cells in the body, including those in the brain. The research team focused specifically on the "sporadic" Alzheimer's disease, the most common form of the disease which results primarily from the presence of the APOE4 susceptibility gene. This same form of the disease had been studied by the team for other early markers. “By identifying oxidative markers in the blood of individuals at risk five years before the onset of the disease, we could make recommendations to slow the onset of the disease and limit the risks”, scientists noted. This breakthrough brings new hope to Alzheimer's research. Once the disease is symptomatic, it is difficult, if not impossible, to reverse it. Meditation training reduces long-term stress, according to hair analysis Max Planck Institute for Human Cognitive and Brain Sciences (Germany), October 11, 2021 Mental training that promotes skills such as mindfulness, gratitude or compassion reduces the concentration of the stress hormone cortisol in hair. This is what scientists from the Max Planck Institute for Human Cognitive and Brain Sciences in Leipzig and the Social Neuroscience Research Group of the Max Planck Society in Berlin have found out. The amount of cortisol in hair provides information about how much a person is burdened by persistent stress. Earlier positive training effects had been shown in acutely stressful situations or on individual days—or were based on study participants' self-reports. According to a study by the Techniker Krankenkasse, 23 percent of people in Germany frequently suffer from stress. This condition not only puts a strain on the well-being of those affected, but it is also linked to a number of physiological diseases, including diabetes, cardiovascular diseases and psychological disorders such as depression, one of the world's leading causes of disease burden (Global Burden of Disease Study, 2017). Therefore, effective methods are being sought to reduce everyday stress in the long term. One promising option is mindfulness training, in which participants train their cognitive and social skills, including attention, gratitude and compassion, through various meditation and behavioral exercises. Various studies have already shown that even healthy people feel less stressed after a typical eight-week training program. Until now, however, it has been unclear how much the training actually contributes to reducing the constant burden of everyday stress. The problem with many previous studies on chronic stress is that the study participants were usually asked to self-assess their stress levels after the training. However, this self-reporting by means of questionnaires could have distorted the effects and made the results appear more positive than they actually were. The reason for such a bias: The participants knew they were training their mindfulness, and a reduction in stress levels was a desired effect of this training. This awareness alone has an impact on subsequent information. "If you are asked whether you are stressed after a training session that is declared as stress-reducing, even addressing this question can distort the statements," explains Lara Puhlmann, doctoral student at the Max Planck Institute for Human Cognitive and Brain Sciences and first author of the underlying publication, which has now appeared in the journal Psychosomatic Medicine. Factors such as social desirability and placebo effects played a role here. Unlike pharmacological studies, for example, in which the study participants do not know whether they have actually received the active substance or not, so-called blinded studies are not possible in mental training. "The participants know that they are ingesting the 'antidote,'" says Puhlmann. "In mindfulness research, we are therefore increasingly using more objective, i.e. physiological, methods to measure the stress-reducing effect more precisely." The concentration of cortisol in hair is considered a suitable measure of exposure to prolonged stress. Cortisol is a hormone that is released when we are confronted with an overwhelming challenge, for example. In that particular situation, it helps put our body on alert and mobilize energy to overcome the challenge. The longer the stress lasts, the longer an increased concentration of cortisol circulates around our body—and the more it accumulates in our hair. On average, hair grows one centimeter per month. To measure the study participants' stress levels during the 9-month training, the researchers, in cooperation with the working group of Clemens Kirschbaum at the University of Dresden, analyzed the amount of cortisol every three months in the first three centimeters of hair, starting at the scalp. The mental training itself was developed as part of a large-scale longitudinal study on the effects of mental training, the ReSource project, led by Tania Singer, scientific director of the Social Neuroscience Research Group. This 9-month mental training program consisted of three 3-month sessions, each designed to train a specific skill area using Western and Far Eastern mental exercises. The focus was either on the factors of attention and mindfulness, on socio-affective skills such as compassion and gratitude, or on so-called socio-cognitive skills, in particular the ability to take perspective on one's own and others' thoughts. Three groups of about 80 participants each completed the training modules in different order. The training lasted up to nine months, 30 minutes a day, six days a week. Less stress, less cortisol And it really showed: After six months of training, the amount of cortisol in the subjects' hair had decreased significantly, on average by 25 percent. In the first three months, slight effects were seen at first, which increased over the following three months. In the last third, the concentration remained at a low level. The researchers therefore assume that only sufficiently long training leads to the desired stress-reducing effects. The effect did not seem to depend on the content of the training. It is therefore possible that several of the mental approaches studied are similarly effective in improving the way people deal with chronic everyday stress. In an earlier study from the ReSource project with the same sample, the researchers had investigated the effects of training on dealing with acute stressful situations. In this study, the participants were placed in a stressful job interview and had to solve difficult maths problems under observation. The results showed that people who had undergone socio-cognitive or socio-affective training released up to 51 percent less cortisol under stress than those who had not been trained. In this case, they did not measure the amount of cortisol in the subjects' hair, but instead acute cortisolsurges in their saliva. Overall, the researchers conclude that training can improve the handling of acute particularly stressful social situations as well as chronic everyday stress. "We assume that different training aspects are particularly helpful for these different forms of stress," says Veronika Engert, head of the research group "Social Stress and Family Health" at the Max Planck Institute for Human Cognitive and Brain Sciences. "There are many diseases worldwide, including depression, that are directly or indirectly related to long-term stress," explains Puhlmann. "We need to work on counteracting the effects of chronic stress in a preventive way. Our study uses physiological measurements to prove that meditation-based training interventions can alleviate general stress levels even in healthy individuals." Study: Moderate carbohydrate intake is a cardiovascular benefit for women Monash University (Australia), October 13, 2021 Women's heart health has been the focus of a recent study by Monash University, with researchers finding that proportional carbohydrate intake and not saturated fat was significantly associated with cardiovascular disease benefit in Australian women. Cardiovascular disease (CVD) is the leading cause of death in women. Poor diet is recognized as both an independent CVD risk factor and a contributor to other CVD risk factors, such as obesity, diabetes mellitus (DM), hypertension, and dyslipidaemia. The research found that in middle-aged Australian women, increasing the percentage of carbohydrate intake was significantly associated with reduced odds of CVD, hypertension, diabetes mellitus, and obesity. Furthermore, a moderate carbohydrate intake between 41.0 percent—44.3 percent of total energy intake was associated with the lowest risk of CVD compared to women who consumed less than 37 percent energy as carbohydrates. No significant relationship was demonstrated between proportional carbohydrate intake and all-cause mortality. In addition, increasing proportional saturated fat intake was not associated with cardiovascular disease or mortality in women; rather, increasing saturated fat intakecorrelated with lower odds of developing diabetes mellitus, hypertension, and obesity. The findings are now published in the British Medical Journal. The results contradict much of the historical epidemiological research that supported a link between saturated fat and CVD. Instead, the results mirror contemporary meta-analysis of prospective cohort studies where saturated fat was found to have no significant relationship with total mortality or CVD. While the cause of this inconsistency in the literature is unclear, it has been suggested that historical studies neglected to adjust for fiber, which is known to help prevent plaque from forming in the arteries. "Controversy still exists surrounding the best diet to prevent CVD," said Sarah Zaman, a former Monash University professor who is now an associate professor at the University of Sydney. "A low-fat diet has historically been the mainstay of primary prevention guidelines, but the major issue within our dietary guidelines is that many dietary trials have predominately involved male participants or lacked sex-specific analyses." She adds: "Further research is needed to tailor our dietary guidelines according to sex." The study's first author Sarah Gribbin, a Doctor of Medicine and BMedSc (Hons) student, says: "As an observational study, our findings only show association and not causation. Our research is purely hypothesis-generating. We are hoping that our findings will spark future research into sex-specific dietary research." The Heart Foundation, which is one of the study's funders, welcomed the focus on women and CVD, which has historically been under-researched. Heart Foundation manager, food and nutrition, Eithne Cahill, cautioned that "not all carbohydrates are created equal." "We know that quality carbohydrate foods such as vegetables and whole grains—including whole grain bread, cereals, and pasta—are beneficial for heart health, whereas poor quality carbohydrates such as white bread, biscuits, cakes, and pastries can increase risk," she said. "Similarly, different fats have different effects on heart health. That is why the Heart Foundation focuses on healthy eating patterns—that is, a combination of foods, chosen regularly over time—rather than a single nutrient or food. Include plenty of vegetables, fruit, and whole grains, and heart-healthy fat choices such as nuts, seeds, avocados, olives and their oils for cooking and a variety of healthy proteins especially seafood, beans and lentils, eggs and dairy." Anti-cancer effects found in natural compound derived from onions Kumamoto University (Japan), October 18, 2021 Research from Kumamoto University, Japan has found that a natural compound isolated from onions, onionin A (ONA), has several anti-ovarian cancer properties. This discovery is a result of research on the effects of ONA on a preclinical model of epithelial ovarian cancer (EOC) both in vivo and in vitro. This research comes from the same group that found ONA suppressed pro-tumor activation of host myeloid cells. According to a 2014 review of cancer medicines from the World Health Organization, EOC is the most common type of ovarian cancer and has a 5-year survival rate of approximately 40%. It has a relatively low lifetime risk that is less than 1%, but that can increase up to 40% if there is a family history of the disease. A majority of patients (80%) experience a relapse after their initial treatment with chemotherapy, therefore a more effective line of treatment is needed. Kumamoto University researchers found that ONA has several effects on EOC. The group's in vitro experiments showed that EOCs, which usually proliferate in the presence of pro-tumor M2 macrophages, showed inhibited growth after introduction of ONA. This was thought to be due to ONAs influence on STAT3, a transcription factor known to be involved in both M2 polarization and cancer cell proliferation. Furthermore, the team found that ONA inhibited the pro-tumor functions of myeloid derived suppressor cells (MDSC), which are closely associated with the suppression of the anti-tumor immune response of host lymphocytes, by using preclinical sarcoma model. ONA was also found to enhance the effects of anti-cancer drugs by strengthening their anti-proliferation capabilities. Moreover, experiments on an ovarian cancer murine model that investigated the effects of orally administered ONA resulted in longer lifespans and inhibited ovarian cancer tumor development. This was considered to be a result of ONA's suppression of M2 polarized macrophages. The research shows that ONA reduces the progression of malignant ovarian cancer tumors by interfering with the pro-tumor function of myeloid cells. ONA appears to activate anti-tumor immune responses by nullifying the immunosuppressive function of myeloid cells. ONA has the potential to enhance existing anti-cancer drugs while also having little to no cytotoxic effects on normal cells. Additionally, side effects in animals have not been seen. With a little more testing, an oral ONA supplement should greatly benefit cancer patients. Risk of chronic diseases caused by exogenous chemical residues Dalian Institute of Chemical Physics (China), October 13, 2021 Chronic diseases are main killers affecting the health of human. The morbidities of major chronic diseases such as obesity, hypertension, diabetes, hyperuricemia and dyslipidemia are as high as 10% to 30%, showing a gradually upward trend as well. More and more studies have shown that environmental pollution is a major health risk factor that cannot be ignored. However, the evidence for their relationship is equivocal and the underlying mechanisms is unclear. Recently, a research group led by Prof. Xu Guowang from the Dalian Institute of Chemical Physics (DICP) of the Chinese Academy of Sciences (CAS) discovered the risk of chronic diseases caused by exogenous chemical residues through metabolome-wide association study. Their findings were published in Environment International on Oct. 8. Researchers from National Institute for Nutrition and Health of the Chinese Center for Disease Control and Prevention, and Tongji Medical College of Huazhong University of Science and Technology were also involved in this study. The researchers discovered positive associations of serum perfluoroalkyl substances (PFASs) with hyperuricemia, and revealed the mechanism of the relationship between the exogenous chemical residues in the serum and the risk of chronic diseases at the metabolic level. The researchers investigated the relationship between 106 exogenous chemical residues and five chronic diseases in 496 serum samples. They revealed the metabolic perturbations related to exogenous chemical residues and chronic diseases by the metabolome-wide association study combined with meeting-in-the-middle approach and mediation analysis, and investigated the further potential underlying mechanism at the metabolic level. "PFASs were the risk factor for hyperuricemia," said Prof. Xu. Lipid species including glycerophospholipids and glycerides presented the strongest correlation with exposure and disease, which were not only positively related to PFASs exposure but also the risk factor for hyperuricemia. "We also found that key mediation metabolites mediated 25% to 68% of the exposure-disease risk relationship," Prof. Xu added. This study provides in-depth etiological understanding for the occurrence and development of diseases, which may be helpful for the early detection of the disease and the identification of early warning markers.
Why does the Bible teach that Jesus will come back “as a thief in the night”? Jesus compared his return and the church's condition to the days of Noah. Why should believers want to be the ones “left behind”? This episode may offer insights that quite possibly you have never considered before! www.thetruelight.net
On this episode, Sonny Bunch (The Bulwark), Alyssa Rosenberg (The Washington Post), and Peter Suderman (Reason) ask whether Dave Chappelle, his new special, and the way Netflix has handled internal and external fallout from its airing, are controversies, or nontroversies. Then the gang reviews The Last Duel, a/k/a Medieval Me Too. (For more on The Last Duel, you can read Sonny here, Alyssa here, and Peter here.) Make sure to listen all the way to end for a special programming note! And check out our bonus episode on our favorite Ridley Scott movies. There are so many to choose from!
Jason Momoa had an emotional moment with his kids on the red carpet at the premiere of James Bond. And Mila Kunis and Ashton Kutcher disagree on how their daughter should handle being physically pushed by another kid at school.
Is Mario still relevant? Are Battle Royales ruining gaming? Can Sonic just please stop? This week, Michael moderates and brings you some hot takes in gaming. Joined by Roger and special guest, Max, the trio disagree, debate, and converge on some of the hottest topics in gaming. Wanna join the discussion? Join the discord! Join our Discord here! Looking for some exclusive Gurus of Gaming merch? Check out our MERCH STORE! Exclusive content & merch available on our PATREON. HIT US UP ON SOCIAL MEDIA! FACEBOOK - INSTAGRAM - TWITTER - WEBSITE Gurus of Gaming is brought to you by Thirteen Palm Trees Podcast Productions
Coach and Maestro THROW DOWN over Baker v Burrow...We consider better nicknames for Valterri Bottas...Are the Dodgers done? Way too early NHL picks...Oklahoma's got a new direction...we make way-too-early NHL champ picks...Guest-a-palooza continues and the 2-minute trivia drill returns...
Are video games teaching your children to eat each other? This week we discuss the time that the industry became under fire in the absolute dumbest way imaginable, along with the origins of an inept advocacy group who hand-waved their way into headlines by picking a fight the Entertainment Software Ratings Board.
Today's wrestling news, including...AEW & CM Punk Charity CONTROVERSY!Raw Hits Record LOW Rating!Daniel Garcia Is All Elite!Top AEW Star Bringing New Gimmick To Dark?!ENJOY!Follow us on Twitter:@AdamWilbourn@AndyHMurray@WhatCultureWWEFor more awesome content, check out: whatculture.com/wwe See acast.com/privacy for privacy and opt-out information.
Are veterinarians “real doctors”? What about vet techs? Are they “medical professionals”? A recent veterinarian versus Peloton quarrel over a "medical professional discount" went public on social media, and we've got all the feels… … Hosts Dr. Ernie Ward (a proud Peloton papa since the beginning) and Beckie Mossor, RVT (not in the Peloton fam) tackle the issue of what to do when the public fails to recognize or respect veterinary professionals was “medical professionals.” This issue is a whole lot bigger than a stationary bike. … Beckie shares the recent social media outrage and "Peloton punching bag” that has dominated many feeds the past week. Beckie postulates that this week's Peloton pushback follows a long history of vets being dissed, that hearkens all the way back to Dr. James Herriot. … Dr. Ward urges our colleagues to take meaningful steps to make positive change, rather than solely engage in online emotional outrage. He also encourages our veterinary organizations, particularly the AVMA and NAVTA, to issue statements and his in elevating the public perception of veterinary professionals. … Both our hosts share personal stories of how they've been slighted in public, and Dr. Ward reveals how he stopped comparing himself to human doctors early in his career and why veterinary professionals shouldn't “take it personally.” … Viewfinders, this is a jam-packed conversation that covers a lot of tough topics. Let us know your thoughts!
New episode alert! The guys jump in, debating the age old green text vs blue text debate (Android vs iOS), give their opinion on the rules and regulations around smoking sections at venues and locations (do they really work?!), Stipe gives an update on his bat & hornet infestation situation (hint, there's a new issue), the latest in NFL controversy & Jamie's bromance with JR Smith. ------- Follow us on Instagram: @jabspodcast Follow us on Twitter: @jabspodcast Follow Stipe: @stipemiocic Follow Jon: @jpchewbac Follow Jamie: @mekalek Email us!: firstname.lastname@example.org
(00:00-7:55): Should the local church be run the same way as a Walmart? Brian and Aubrey discussed this and commented on a tweet from Carey Nieuwhof, “Why is the local Walmart run better than the local church? That's a tragedy.” (7:55-26:36): Taylor Schumann, writer and activist, joined Brian and Aubrey to talk about her new book, “When Thoughts and Prayers Aren't Enough: A Shooting Survivor's Journey into the Realities of Gun Violence.” Learn more about Taylor at taylorschumann.com and connect with her on Twitter at @taylorsschumann (26:36-36:20): Brian and Aubrey talked about cancel culture, freedom of speech, and the controversy surrounding Dave Chappelle's Netflix special “The Closer.” (36:20-44:06): Brian and Aubrey shared their thoughts on Traci Rhoades tweet, “A willingness to see other viewpoints doesn't mean you don't have your own. Thinking it does misses the point.” (44:06-53:54): Brian and Aubrey chatted about the importance of words of affirmation and reacted to the following stories: “Iris Apfel shares her secret to living to 100” “This 2-year-old's morning mantra is the pep talk we needed today” See omnystudio.com/listener for privacy information.
Watch today's BONUS News Video: https://youtu.be/3PhLCA870k4 Go to http://getroman.com/Phil for $15 off your first ED treatment + free two-day shipping if prescribed! More PDS: https://youtu.be/2ZE6oBVa5fA TEXT ME! +1 (813) 213-4423 Get More Phil: https://linktr.ee/PhilipDeFranco -- 00:00 - Jordan Klepper & Channel 5 Videos for Self Care 03:21 - Hasan Piker Ignites Exploitation Debate 05:51 - Sponsor 06:34 - Group Holding American and Canadian Missionaries Captive in Haiti Seeks $17 Million Ransom 08:48 - SCOTUS Rules in Favor of Police in Two Qualified Immunity Cases 10:59 - Trump Sues Jan. 6 Committee Over Records Requests -- ✩ TODAY'S STORIES ✩ Jordan Klepper & Channel 5 Videos for Self Care: https://youtu.be/4oXZXT3D0UE https://youtu.be/B9v6q5YzbGA Hasan Piker Ignites Exploitation Debate: https://twitter.com/VICE/status/1450386281121333250 Group Holding American and Canadian Missionaries Captive in Haiti Seeks $17 Million Ransom: https://roguerocket.com/2021/10/19/gang-that-kidnapped-american-and-canadian-missionaries-in-haiti-seeks-17-million-ransom/ SCOTUS Rules in Favor of Police in Two Qualified Immunity Cases: https://roguerocket.com/2021/10/19/scotus-police-qualified-immunity/ Trump Sues Jan. 6 Committee Over Records Requests: https://www.nytimes.com/2021/10/18/us/politics/trump-lawsuit-capitol-riot.html ✩ STORIES NOT IN TODAY'S SHOW ✩ SEC Releases Long-Awaited Report on January Memestock Frenzy, Pokes Hole in “Short Squeeze” Narrative: https://roguerocket.com/2021/10/19/gme-sec/ —————————— Executive Producer: Amanda Morones Edited by: James Girardier, Julie Goldberg, Maxwell Enright Art Department: Brian Borst, William Crespo Writing/Research: Philip DeFranco, Cory Ray, Brian Espinoza, Maddie Crichton, Lili Stenn, Neena Pesqueda Production Team: Zack Taylor, Emma Leid ———————————— #DeFranco #HasanPiker #JordanKlepper ————————————
Jimmy Smith breaks down the controversy that occurred between rounds with corner advice Aspen Ladd was getting from her head coach and whether it crossed any sort of line (:30), and discusses the corner controversy, NBA opening Day, and Fedor's return the cage with Bellator Play-by-Play announcer/Voice of the Celtics Sean Grande (16:52).
Our video studio is finally ready, revealing his birthday present, going to a gay bar, deleting private messages, and the age old debate of standing vs sitting while you pee. This episode is fully loaded, sit back, relax, enjoy follow us on Instagram @lightweightspod // @ilyafeddy // @ughitsjoe --- Support this podcast: https://anchor.fm/lightweights/support
On Monday's episode of Futbol Americas, Herculez and Sebastian debate Zack Steffen's lack of minutes at Man City. How worried should Gregg Berhalter and USMNT be? The guys recap all the weekend action by USMNT and Mexican Nation Team players across Europe, including Dest and Lozano. Later, Herc and Sebi discuss the sanctions dealt by FIFA to Panama and El Salvador for their fan's behavior. Next, we recap the weekend action in Liga MX and MLS in the segments Praise or Shade? and The Good, Bad and Ugly. Finally, we take a look at the NWSL playoff picture to close out the show.
Controversy struck Serie A this past weekend (surprise surprise!) as Roma scored a goal that was disallowed for a penalty kick in their favour, which was subsequently missed and Juventus won. Nobody knew what was going on, especially when Jose Mourinho didn't rage about it.Then upon Simone Inzaghi's return to the Stadio Olimpico, Inter got mad over Lazio not kicking the ball out when their player was faking an injury. It all got a bit crazy. Then a red card came out after the match and who'd be a referee?!?!Elsewhere, an excellent comeback from 2 goals down saw the agony and the ecstasy of football: an impressive Milan victory secured with a heartbreaking own-goal in the Verona net, and emotional scenes after the match as the forgotten man of Milanello, Samuel Castillejo, produced a fine performance to help rescue his team and earn the adulation of San Siro, Silvio Pioli and his team mates.Victor Osimhen inspired Napoli to their 8th win in a row to keep up their winning record and stay on top of the Serie A table.And then Nicky and Mina review the "Footballgate" episode of the new Netflix documentary series "Bad Sport", in which Mina Rzouki is featured, detailing the calciopoli scandal that saw the biggest upheaval in the history of Italian football.01:00 Juventus v Roma21:10 Lazio v Inter32:30 Supporters shoutout36:00 Milan v Verona50:00 Napoli v Torino58:50 Bad Sport Netflix discussionDon't forget our ChroniclesQ&A mailbag show on Friday.Tweet us your questions to @serieAchronpod with the hashtag #ChroniclesQandAFor sponsorship opportunities with Serie A Chronicles podcast email email@example.com.Find Serie A Chronicles on social media (all the links here) and at our website serieachronicles.com.Please give us a rating and review on Apple Podcasts.You can also become a Chronicles Tifoso by supporting the podcast to help keep us running, at serieachronicles.com/supporter.Serie A Chronicles is a Media Chronicles production.Digital content and social media by Calido Media.Support this show http://supporter.acast.com/serie-a-chronicles. See acast.com/privacy for privacy and opt-out information.
Brendan comments on the Ariel Helwani situation, recaps Bellator 268 and UFC's Fight Night and talks Corey Anderson's finish of Ryan Bader, why ex-UFC fighters feel they have more to prove when joining other promotions, controversy surrounding Aspen Ladd's coach, Conor McGregor accused of attacking a popular Italian DJ in Rome, Jon Jones being asked by Mike Winklejohn to leave the gym, update on Chuck Liddell's arrest, this weekend's Paulo Costa vs Marvin Vettori and Fedor Emelianenko vs. Tim Johnson and much more. See omnystudio.com/listener for privacy information.
Recently, streaming platform Netflix came under a firestorm of criticism from the LGBTQ+ community both outside the company and internally, with transgender Netflix staff planning a walkout on 20th October. All this was caused by the launch of Dave Chapelle's final standup comedy special on their platform, which contained “transphobic” content, and the CEO's defense of the material in spite of the backlash. Why is everyone closely watching this controversy, and why would it matter to someone in Singapore? Elsewhere, the Hooters franchise unveiled a new uniform for their servers that ruffled feathers, so much so that they had to backtrack on the implementation of these uniforms. Find us here! Our YLB Subreddit for detailed show notes and mindblowing discussions! YLB's own TikTok featuring 2 boom-llenials attempting to connect with Gen Z uwu Our YLB YouTube channel to watch videos of all our guest interviews! Comedian Dave Chapelle's Netflix special ignites “transphobia” controversy Netflix Trans Employees Plan Walkout Over Dave Chappelle Special | Variety A timeline of Netflix's Dave Chapelle special fallout | sfgate Ted Sarandos' Defense of Dave Chappelle Special Misses the Point | Variety Dave Chappelle's ‘The Closer' Is Not a Simple Victim-Bully Story | The Atlantic Actually, Netflix, Content Like Dave Chappelle's Transphobic Comedy Special Does “Directly Translate To Real World Harm” | Yahoo Family of trans woman who Dave Chapelle in Netflix special said was hounded to death for defending his jokes in 2019 slam woke mob trying to cancel him: Sister says you can't 'demand everyone see it your way' | Daily Mail Netflix's support of Dave Chappelle is setting a dangerous precedent. Here's why. | USA Today Dave Chappelle Accomplished Exactly What He Wanted To | Slate Dave Chappelle vs. trans people vs. Netflix | Vox Hooters staff complain that their new uniforms are inappropriate Hooters amends uniform policy after employees condemn ‘disturbing' new shorts One Shiok Comment Comment from GoldGene3631 Comment from cutegirlgirl39 One Shiok Thing How do lava lamps help with Internet encryption? | Cloudflare #1718 - Dr Sanjay Gupta | The Joe Rogan Experience
Dr. Natalia Wiechowski helps people shine! She's a podcaster, Linkedin creator, author, course creator, and blogger! In order to teach those things so she believed she needed a solid opinion on each. Her parents taught her if it doesn't work out the first time, train and you'll do better the next time! She believes in finding what is aligned with your wishes and needs by doing your homework! Better Call Daddy: The Safe Space for Controversy. At 29, at the peak of Dr. Natalia's career and unhappiness, she quit her job and started from scratch. During a nine-month sabbatical, she committed to designing her dream life and founded Think Natalia. Her obsession is helping businesses to get more visibility, clients and become the voice of their niche through the art of social selling on LinkedIn. Dr. Natalia consults and speaks globally, she comes from Hanover (Germany) and lives in Dubai. She started as a Social Scientist, turned into a Dr. of Philosophy, Personal Branding Strategist, flawsome Edutainer, bilingual Keynote Speaker, 2x bestselling Author, Top 100 Leader in Education and LinkedIn Marketing Unicorn with 108,000+ followers. Performance, good food, and stuff that glitters make her happy. Natalias LinkedIn + Instagram profile: linkedin.com/in/nataliawiechowski instagram.com/thinknatalia?utm_medium=copy_link • LinkedIns perfect five guide: https://perfectfivesystem.com/course Me and my daddy would love to hear from you podchaser.com/bettercalldaddy or ratethispodcast.com/bettercalldaddy
Hour 2 of A&G features St. Bernard sized rodents. Teen girls are developing ticks from tiktok. The growing concern of politics and church, and Dr. Fauci on his controversy. See omnystudio.com/listener for privacy information.
Hour 2 of A&G features St. Bernard sized rodents. Teen girls are developing ticks from tiktok. The growing concern of politics and church, and Dr. Fauci on his controversy. See omnystudio.com/listener for privacy information.
Hour 2 of A&G features St. Bernard sized rodents. Teen girls are developing ticks from tiktok. The growing concern of politics and church, and Dr. Fauci on his controversy. Learn more about your ad-choices at https://www.iheartpodcastnetwork.com
Boys manage to record two podcasts back to back for a change and it starts off with a clever greeting by Kooly. This leads to a conversation about Auslan and also celebrity dancing reality tv shows. Controversy in the MLB see the Dodgers advance and the Giants knocked out of the post season. NFL season is in full swing, Tommy's Buffalo Bills are looking good and there's even been some games played in Jimmy's neck of the woods at Tottenham Hotspur Stadium.The Caulfield Cup and Everest have just been run. Melbourne is back to school in seat but not with some hiccups for Kooly. News reports advise of a liquor shortage due to all the glass being used for vaccine vials. Petrol prices are high, Tommy sees a family of deer literally on his doorstep and Kooly's FTA recalls his 2005 Contiki tour shenanigans. Note: this episode was recorded on October 16th 2021. Opening and Closing music by Jessica Lorraine (https://www.jessicalorrainemusic.com) Artwork/Logo thanks to Hannah Lorraine. Disclaimer: We are not legal, financial, political, medical or crytocurrency experts so please consult with trained professionals. www.noodlesinacupboard.com Facebook: @NoodlesInACupboard Twitter: @Noodlesinacupb1
Episode 191: On the evening of July 30, 2008, Tim McLean, a 22-year-old Canadian carnival barker was returning home to Winnipeg riding a Greyhound bus when he was viciously stabbed, beheaded, and cannibalized by another passenger about 18 km west of Portage la Prairie, Manitoba. After arriving on scene, RCMP watched for hours as the perpetrator, Vince Li, 40, desecrated Tim's body inside the bus after the driver and remaining passengers had fled, powerless to stop the man's frenzy. Less than a year later, Vince Li was found not criminally responsible (NCR) for Tim McLean's slaying, but held in a Manitoba psychiatric institution from which he was released just 6 years later. Sources: Cold Facts of the Case – Tim's Law YouTube — R.I.P Tim McLean - July 30, 2008 Greyhound Bus Tragedy YouTube — TIMOTHY MCLEAN KILLING (CAROL DE DELLEY INTERVIEW) AFTERMATH OF MURDER: SURVIVOR STORIES Justice served with the absolute discharge of Vince Li – The Manitoban BOOK: Shrunk — Crime and Disorders of the Mind by Lore Proceed with Extreme Caution: The Not Criminally Responsible Defence | CanLII Vincent Li found not criminally responsible for murder - Winnipeg Free Press DocumentCloud — Manitoba Criminal Code Review Board decision Timeline of decisions in the case of Vince Li - Winnipeg | Globalnews.ca Vince Li Archives - Dying Words YouTube — Vince Li — “Please, kill me.” YouTube — The Fifth Estate — Bus 1170 : Vince Li and the Greyhound Bus Murder (2011) Killing of Tim McLean - Wikipedia Vince Li | News, Videos & Articles | Globalnews.ca Looking back at the Greyhound bus beheading a decade down the road | Globalnews.ca Not Criminally Responsible Reform Act (backgrounder) — Canada News Centre Not Criminally Responsible Reform Act http://summit.sfu.ca/system/files/iritems1/16395/etd9553_TMiller.pdf Talk:Killing of Tim McLean - Wikipedia How to Be a Juggalo: 12 Steps (with Pictures) - wikiHow Fun A Conversation With Vince Li - Steinbachonline.com Vince Li, man who beheaded Greyhound bus passenger, seeks absolute discharge | CBC News R.I.P Tim McLean — Facebook Group MCLEAN TIMOTHY - Obituaries - Winnipeg Free Press Passages Timeline to the Greyhound bus killing | CBC News Vince Weiguang Li | Murderpedia, the encyclopedia of murderers Support the show: https://www.patreon.com/darkpoutine See omnystudio.com/listener for privacy information.
Despite a valiant effort from a shorthanded roster, the Avalanche fall for the first time this season with a 5-3 loss to the St. Louis Blues, but not without plenty of controversy. A late disallowed goal stopped an incredible Avalanche comeback dead in its tracks, and the leagues inconsistency rears its head once more, costing the Avs a point. Despite the controversy, what could the Avalanche have done differently without their stars to get a better result? Finally, the Avalanche were confirmed to have been in on the Jack Eichel sweepstakes at one point. What would a Jack Eichel trade have looked like for the Avalanche, and would it have been a good idea to begin with? Welcome to The Tell It Avs It Is Podcast, your home for everything Colorado Avalanche on The Hockey Podcast Network! Join hosts Griffin Youngs from Fansided.com and Christian Bolle from DenverNoseBleed.com every Monday and Thursday as they brings you up to date and intriguing analysis on all things Colorado Avalanche and NHL. Follow Griffin on Twitter: @GYoungsNHL Follow Christian Bolle on Twitter: @Christian_Bolle Follow the show on Twitter: @TellItAvsItIs The Hockey Podcast Network - @hockeypodnet
You've probably already heard about the controversy or even weighed in on Dave Chappelle's final comedy special for Netflix, The Closer, where the comedy legend spends most of the hour taking an irreverent and critical look at the collective struggle of LGBTQ folks.Despite being a comedy special everyone loves to hate, Chappelle does bring up some wonderful sex positive material like wondering what MLK Jr would have to say about glory holes. Unfortunately, Chapelle proclaims himself team TERF while perpetuating some harmful ideas about trans bodies and compares trans women's genitals to vegan burgers.The Closer is probably the longest set any comedian has ever spent talking on LGBTQ+ issues and is way more complicated than clickbait articles would have you believe.All controversy aside, we are puzzled that Dave Chappelle would align himself with the same regressive people he claimed were the reason why he abruptly walked away from a 50 million dollar paycheck when he quit his successful show on Comedy Central over 15 years ago.MATT BROWN: https://www.msbrowncomedy.com/GET YOUR FREE ONE YEAR DOT GAY DOMAIN: www.feastoffun.gayACCESS THOUSANDS OF LEGENDARY FEAST OF FUN SHOWS with NO ADS:https://feastoffun.com/plusToday comedian Matt Brown, Ms Brown if you're nasty, joins us to take a look at Dave Chappelle's comedy special “The Closer” and the surrounding controversy around his comments on LGBTQ plus folks and trans bodies.Plus-- Star Trek's William Shatner responds to his co-star's George Takei comments on him being unfit for spaceflight due to his age and weight. Oh my!
Today we do a retro review of Parasyte the anime, Lance has finally watched Black Widow and Daredevil show runner Steven DeKnight comes out against Marvel Editor in Chief, C.B. Cebulski and his time pretending to be a Japanese man. Stay Colorful --- This episode is sponsored by · Anchor: The easiest way to make a podcast. https://anchor.fm/app --- Send in a voice message: https://anchor.fm/cfa7/message Support this podcast: https://anchor.fm/cfa7/support
TRIGGER WARNING: This episode discusses pedophilia and incest. If any of these two subjects will retraumatize you, PLEASE DO NOT LISTEN!! We don't want to re-traumatize anyone. In this episode, the boys discuss how to get girls, the EDP controversy, illegal acts in the gaming community, How the Pandemic has changed them, and so much more! Sit back, grab a drink, and enjoy some funny conversations with Tony, William, and Trevor! [2:10] highs and lows [7:25] Hoe-ing [10:16] confidence + how to get girls [18:36] William got the strap!! [21:00] Trevor's date stories [22:08] William's final relationship advice [24:16] Condemning Pedophilia [34:00] Incest Is Not Okay [34:22] The EDP Controversy [36:58] Back to condemning pedophiles [39:58] illegal s*** In the gaming community [41:43] We Stand By What We Say [44:46] Pornstars we've grown up on [45:59] Would you let trump eat yo *** for 2 million dollars CUT HERE [49:21] The Among Us Craze [50:49] How are we enjoying the new year? [59:09] Our Thoughts On the Pandemic [1:12:43] What We Want To Do Now That The Pandemic Is “Over” [1:14:34] What We Want To Grow On [1:19:13] True Masculinity [1:20:55] Truly Being Yourself [1:26:01] Cancel Culture Don't forget to rate us and send your questions to firstname.lastname@example.org Social Media: @life_ofaballer @trevoruriarte @billiam.peck @rashawn432 --- This episode is sponsored by · Anchor: The easiest way to make a podcast. https://anchor.fm/app Support this podcast: https://anchor.fm/tony-house/support
On this episode of K100Talks...the crew discusses Netflix's response to the recent controversy over Dave Chappelle's new stand up special, when did attitudes and sensitivities begin to change in such a harsh manner, bad takes on social media. changes in parenting, how much does entertainment really influence, over-medication of children, teens, and adults and more!Get Interactive on Twitter @Konnan5150 @TheRealDisco @MaskedRepublic @JFFeeney3rd @TheCCNetwork1 @K100Konnan Check out our Patreon site at Konnan.me and Patreon.com/Konnan for extra audio, FULL AD FREE episodes, exclusive video, listener roundtable discussion shows, weekly watch-a-longs, call in shows with Konnan and DI, plus so much more!
Eduardo Perez joins to talk about the Dodgers win last night against the Giants, the controversy about the last call and about Game 1 of the ALCS tonight between Astros vs Red Sox. Dan Graziano also joins to talk talk about how much Tom Brady has changed the Bucs, Lamar Jackson evolving his game and his article about the timeline with Deshaun Watson.