Podcasts about oocyte

Take a sneak peek at this month's Fertility & Sterility! Articles discussed this month are:   04:20 Poor intracytoplasmic sperm injection outcome in infertile males with azoospermia factor c microdeletions 10:17 Patients with a body mass index of ≥45 kg/m2 can safely undergo oocyte retrievals and anticipate similar assisted reproductive technology outcomes 21:26 Increased endometrial thickness up to 12 mm is associated with increased odds of live birth among fresh and frozen-thawed autologous transfers with or without preimplantation genetic testing 34:21 The chorionic bump is a predictor of miscarriage: a retrospective analysis of 13,656 in vitro fertilization pregnancies 47:01 Prospective validation of anti-Müllerian hormone cutoff to determine polycystic ovarian morphology: HARMONIA study 58:21 Effect of glucagon-like peptide 1 agonist medications on weight loss in patients with and without polycystic ovary syndrome View Fertility and Sterility at https://www.fertstert.org/    

Take a sneak peek at this month's Fertility & Sterility! Articles discussed this month are:   08:57 Trends in Use of Preimplantation Genetic Testing for Aneuploidy Before Dobbs, After Dobbs Leak, and After Dobbs Final Ruling 20:12 The impact of PGT-A on time to live birth in IVF. 32:02 A Nationwide Analysis of the Trends in Permanent Contraception Utilization Before and After the Dobbs Ruling   37:28 Use of assisted reproductive technologies for male and female infertility and perinatal outcomes  50:50 Assisted hatching decreases pregnancy outcomes in vitrified donor oocytes 56:42 Use of medically assisted reproduction and the risk of multiple live birth across sexual orientation groups—results from a national longitudinal cohort   View the August 2025 issue, Vol 124: Issue 2 - https://www.fertstert.org/issue/S0015-0282(25)X0008-X View Fertility and Sterility at https://www.fertstert.org/  

Antoni J. Duleba, M.D. outlines the broad scope of reproductive endocrinology and infertility, emphasizing care across a woman's lifespan—from adolescence through menopause. He explains common endocrine conditions like polycystic ovary syndrome (PCOS), endometriosis, and menstrual disorders, all of which can affect fertility and overall health. Duleba highlights advances in fertility preservation, especially for patients undergoing cancer treatment, and notes the rising need for such services as more women delay childbearing. He also addresses efforts to improve hormonal therapies, IVF outcomes, and treatments that target inflammation and the microbiome. In addition to medical innovation, he points to social and financial barriers that continue to limit access to reproductive care. Series: "Motherhood Channel" [Health and Medicine] [Show ID: 40672]

Antoni J. Duleba, M.D. outlines the broad scope of reproductive endocrinology and infertility, emphasizing care across a woman's lifespan—from adolescence through menopause. He explains common endocrine conditions like polycystic ovary syndrome (PCOS), endometriosis, and menstrual disorders, all of which can affect fertility and overall health. Duleba highlights advances in fertility preservation, especially for patients undergoing cancer treatment, and notes the rising need for such services as more women delay childbearing. He also addresses efforts to improve hormonal therapies, IVF outcomes, and treatments that target inflammation and the microbiome. In addition to medical innovation, he points to social and financial barriers that continue to limit access to reproductive care. Series: "Motherhood Channel" [Health and Medicine] [Show ID: 40672]

Antoni J. Duleba, M.D. outlines the broad scope of reproductive endocrinology and infertility, emphasizing care across a woman's lifespan—from adolescence through menopause. He explains common endocrine conditions like polycystic ovary syndrome (PCOS), endometriosis, and menstrual disorders, all of which can affect fertility and overall health. Duleba highlights advances in fertility preservation, especially for patients undergoing cancer treatment, and notes the rising need for such services as more women delay childbearing. He also addresses efforts to improve hormonal therapies, IVF outcomes, and treatments that target inflammation and the microbiome. In addition to medical innovation, he points to social and financial barriers that continue to limit access to reproductive care. Series: "Motherhood Channel" [Health and Medicine] [Show ID: 40672]

Antoni J. Duleba, M.D. outlines the broad scope of reproductive endocrinology and infertility, emphasizing care across a woman's lifespan—from adolescence through menopause. He explains common endocrine conditions like polycystic ovary syndrome (PCOS), endometriosis, and menstrual disorders, all of which can affect fertility and overall health. Duleba highlights advances in fertility preservation, especially for patients undergoing cancer treatment, and notes the rising need for such services as more women delay childbearing. He also addresses efforts to improve hormonal therapies, IVF outcomes, and treatments that target inflammation and the microbiome. In addition to medical innovation, he points to social and financial barriers that continue to limit access to reproductive care. Series: "Motherhood Channel" [Health and Medicine] [Show ID: 40672]

Antoni J. Duleba, M.D. outlines the broad scope of reproductive endocrinology and infertility, emphasizing care across a woman's lifespan—from adolescence through menopause. He explains common endocrine conditions like polycystic ovary syndrome (PCOS), endometriosis, and menstrual disorders, all of which can affect fertility and overall health. Duleba highlights advances in fertility preservation, especially for patients undergoing cancer treatment, and notes the rising need for such services as more women delay childbearing. He also addresses efforts to improve hormonal therapies, IVF outcomes, and treatments that target inflammation and the microbiome. In addition to medical innovation, he points to social and financial barriers that continue to limit access to reproductive care. Series: "Motherhood Channel" [Health and Medicine] [Show ID: 40672]

Antoni J. Duleba, M.D. outlines the broad scope of reproductive endocrinology and infertility, emphasizing care across a woman's lifespan—from adolescence through menopause. He explains common endocrine conditions like polycystic ovary syndrome (PCOS), endometriosis, and menstrual disorders, all of which can affect fertility and overall health. Duleba highlights advances in fertility preservation, especially for patients undergoing cancer treatment, and notes the rising need for such services as more women delay childbearing. He also addresses efforts to improve hormonal therapies, IVF outcomes, and treatments that target inflammation and the microbiome. In addition to medical innovation, he points to social and financial barriers that continue to limit access to reproductive care. Series: "Motherhood Channel" [Health and Medicine] [Show ID: 40672]

Antoni J. Duleba, M.D. outlines the broad scope of reproductive endocrinology and infertility, emphasizing care across a woman's lifespan—from adolescence through menopause. He explains common endocrine conditions like polycystic ovary syndrome (PCOS), endometriosis, and menstrual disorders, all of which can affect fertility and overall health. Duleba highlights advances in fertility preservation, especially for patients undergoing cancer treatment, and notes the rising need for such services as more women delay childbearing. He also addresses efforts to improve hormonal therapies, IVF outcomes, and treatments that target inflammation and the microbiome. In addition to medical innovation, he points to social and financial barriers that continue to limit access to reproductive care. Series: "Motherhood Channel" [Health and Medicine] [Show ID: 40672]

Dr. Amparo Santamaria describes a #research paper she co-authored that was #published in Volume 17, Issue 6 of Aging (Aging-US), titled “Enhancing oocyte activation in women with ovarian failure: clinical outcomes of the Stem Cell Regenera study using G-CSF mobilization of peripheral blood stem cells and intraovarian injection of stem cell factor-enriched platelet rich plasma in real-world-practice.” DOI - https://doi.org/10.18632/aging.206274 Corresponding author -Amparo Santamaria - Amparo.santamaria@ivirma.com Video interview - https://www.youtube.com/watch?v=oRFJNwnXZWI Abstract The study assesses the effectiveness and safety of the Stem Cell Regenera Treatment for oocyte activation in women with ovarian failure, including conditions such as Poor Ovarian Response (POR), Diminished Ovarian Reserve (DOR), and Premature Ovarian Insufficiency (POI). This retrospective observational study was conducted from January 2023 to December 2024 at the IVIRMA Alicante Clinics in Spain. Women diagnosed with ovarian failure participated in the study, which involved mobilizing Hematopoietic Stem Cells from bone marrow into peripheral blood using granulocyte colony- stimulating factor (G-CSF). This was followed by an intraovarian injection of Stem Cell Factor- enriched Platelet Rich Plasma (SCFE-PRP). The primary outcome measures were the rate of oocyte activation, leukocytes and stem cell count, and pregnancy rates. Oocyte activation was defined as an increase in total Antral Follicle Count of three or more follicles after treatment and/or at least a 20% rise in Anti-Müllerian Hormone levels. Safety was assessed based on adverse effects. Pregnancy rates were evaluated for both spontaneous gestation and following in vitro fertilization (IVF) treatment. A total of 145 women participated: the overall activation rate was 68.28%, with 7.07% achieving spontaneous gestation and 14.14% achieving pregnancy following IVF. Mobilization of CD34+ cells was successful in all participants, with an average collection of 32.96 CD34+ cells/μl. No severe adverse effects were observed. The study concluded that the Stem Cell Regenera Treatment is effective and safe for oocyte activation in women with ovarian failure in real-world practice. Sign up for free Altmetric alerts about this article - https://aging.altmetric.com/details/email_updates?id=10.18632%2Faging.206274 Subscribe for free publication alerts from Aging - https://www.aging-us.com/subscribe-to-toc-alerts Keywords - aging, Stem Cell Regenera, oocyte activation, ovarian regeneration, G-CSF, SCFE-PRP, ovarian failure To learn more about the journal, please visit our website at https://www.Aging-US.com​​ and connect with us on social media at: Facebook - https://www.facebook.com/AgingUS/ X - https://twitter.com/AgingJrnl Instagram - https://www.instagram.com/agingjrnl/ YouTube - https://www.youtube.com/@AgingJournal LinkedIn - https://www.linkedin.com/company/aging/ Bluesky - https://bsky.app/profile/aging-us.bsky.social Pinterest - https://www.pinterest.com/AgingUS/ Spotify - https://open.spotify.com/show/1X4HQQgegjReaf6Mozn6Mc MEDIA@IMPACTJOURNALS.COM

Take a sneak peak at this month's Fertility & Sterility! Articles discussed this month are:   04:20 A Pilot Study to Investigate the Clinically Predictive Values of Copy Number Variations Detected by Next-Generation Sequencing of Cell-Free Deoxyribonucleic Acid in Spent Culture Media   17:16 The Impact of Microfluidics Sperm Processing on Blastocyst Euploidy Rates Compared with Density Gradient Centrifugation: A Sibling Oocyte Double-Blinded Prospective Randomized Trial   24:12 Prediction of Pregnancy-Related Complications in Women Undergoing Assisted Reproduction, Using Machine Learning Models   38:51 The Effect of Laser-Assisted Hatching on Vitrified/Warmed Blastocysts: The ALADDIN Randomized Controlled Trial   48:47 Assessment of Clinical Pregnancies in Up to Eight Ovarian Stimulation with Intrauterine Insemination Treatment Cycles in Those Unable to Proceed with In Vitro Fertilization   01:00:43 Intravaginal Exposure to Seminal Plasma After Ovum Pick-Up Does Not Increase Live Birth Rates after In Vitro Fertilization or Intracytoplasmic Sperm Injection Treatment:  A Double-Blind, Placebo-Controlled Randomized Trial   01:07:21 Predictive Models of Miscarriage on the Basis of Data from the Preconception Cohort Study   View this issue at https://www.fertstert.org/issue/S0015-0282(24)X0006-0 View Fertility and Sterility at https://www.fertstert.org/

Take a sneak peak at this month's Fertility & Sterility! Articles discussed this month are:   03:32 How Many Infants Have Been Born With the Help of Assisted Reproductive Technology? 11:33 Adding Short-Duration Gonadotropin-Releasing Hormone Antagonist and Gonadotropin to Natural Cycle Frozen Embryo Transfer Allowed Scheduling of Transfer Day Without Compromising Live Birth 24:42 Sublingual Progesterone Lozenges Are a Viable Alternative to Intramuscular Porgesterone-in-Oil for Programmed Frozen Embryo Transfer Cycles 33:08 Perinatal Outcomes of Progesterone in Natural Frozen-Thawed Embryo Transfer Pregnancies: Insights From 2 Randomized Controlled Trials 42:38 Cost Effectiveness Analysis of Uterus Transplantation vs. Gestational Carrier for Treatment of Absolute Uterine Factor Infertility in the United States AND Comparing Gestational Carrier with Uterine Transplantion in Uterine-Factor Infertility: A Cost-Effectiveness Analysis 01:03:28 Extended Intrauterine Balloon Stent Use to Prevent Adhesion Reformation After Hysteroscopic Adhesiolysis, A Randomized Trial View the July 2025 issue, Vol 124: 1-178 - https://www.fertstert.org/issue/S0015-0282(25)X0006-6 View Fertility and Sterility at https://www.fertstert.org/  

Join us for a deep dive into the IVF patient journey with special guest Kelly Gonda, a passionate pharmacist and Fertility Nurse Practitioner. In this episode, we explore how pharmacists can improve safety, outcomes, and access to fertility treatment by understanding the science of in vitro fertilization and the medications involved.

Join current F&S editors Drs. Micah Hill, Kurt Barnhart, and Allison Eubanks in an engaging discussion with past Editors-in-Chief, Drs. Alan DeCherney, Craig Niederberger, and Antonio Pellicer!  View Fertility and Sterility at https://www.fertstert.org/  

Take a sneak peek at this month's Fertility & Sterility! Articles discussed this month are:   02:17 Effects of preimplantation genetic testing for aneuploidy on embryo transfer outcomes in women of advanced reproductive age with no more than three retrieved oocytes 15:30 Using National IVF Registries to Validate Clinical Outcomes Following IVF Covered by Health Insurance  29:38 Impact of corpus luteum number on maternal pregnancy and birth outcomes: the Rotterdam Periconception Cohort 39:15 Systematic review and Meta-analysis of the impact of the re-freezing and re-biopsy embryos on reproductive outcomes in patients undergoing freeze-thaw embryo transfer   50:20 A blastocyst's implantation potential is linked to its originating oocyte cohort's blastulation rate: evidence for a cohort effect 01:02:56 Linzagolix rapidly reduces heavy menstrual bleeding in women with uterine fibroids: An analysis of the PRIMROSE 1 & 2 trials  View Fertility and Sterility at https://www.fertstert.org/

Take a sneak peak at this month's Fertility & Sterility! Articles discussed this month are:   4:08 Classification system of human ovarian follicle morphology: recommendations of the National Institute of Child Health and Human Development - sponsored ovarian nomenclature workshop  12:32 Impact of Prednisone on Vasectomy Reversal Outcomes (iPRED Study): Results from a Randomized, Controlled Clinical Trial 21:38 Triggering oocyte maturation in IVF treatment in normal responders: a systematic review and network meta-analysis 33:57 Parental Balanced Translocation Carriers do not have Decreased Usable Blastulation Rates or Live Birth Rates Compared to Infertile Controls  45:28 A re-look at the relevance of TSH and thyroid autoimmunity for pregnancy outcomes: Analyses of RCT data from PPCOS II and AMIGOS View Fertility and Sterility May 2025, Volume 123, Issue 5:  https://www.fertstert.org/issue/S0015-0282(25)X0004-2 View Fertility and Sterility at https://www.fertstert.org/

Take a sneak peek at this month's Fertility & Sterility! Articles discussed this month are:   01:47 Puberty progression in girls with Turner syndrome after ovarian tissue cryopreservation 14:55 Optimal Restoration of Spermatogenesis following Testosterone Therapy using hCG and FSH 27:58 Human embryos with segmental aneuploidies display delayed early development: a multi-centre morphokinetic analysis 39:56 Neurodevelopmental or behavioural disorders in children conceived after assisted reproductive technologies: A nationwide cohort study 45:23 Efficacy and safety of estetrol (E4) 15 mg/drospirenone (DRSP) 3 mg combination in a cyclic regimen for the treatment of primary and secondary dysmenorrhea: A multicenter, placebo-controlled, double-blind, randomized study 51:13 Ovulation trigger versus spontaneous LH surge on live birth rate following frozen embryo transfer in a natural cycle: a randomized controlled trial 60:29 A Cost Analysis of Clomiphene Citrate, Letrozole and Gonadotropin with Intrauterine Insemination using Outcome Data from the AMIGOS Trial   View Fertility and Sterility at https://www.fertstert.org/

Take a sneak peek at this month's Fertility & Sterility! Articles discussed this month are:   01:46 It is time to rethink coordination of fresh oocyte retrievals with microscopic testicular sperm extraction 02:55 Rescue intracytoplasmic sperm injection improved cumulative live birth rate for cycles with second polar body extrusion rate

Take a sneak peek at this month's Fertility & Sterility! Articles discussed this month are:   01:03 (Not) My body, my choice? - Should physicians be facilitating gestational carrier arrangements in the absence of medical indication? 05:22 Morphological changes of endometriomas during pregnancy and after delivery detected using ultrasound 12:17 Hormone-free vs. follicle-stimulating hormone–primed infertility treatment of women with polycystic ovary syndrome using biphasic in vitro maturation: a randomized controlled trial 24:37 Association of in vitro fertilization with severe maternal morbidity in low-risk patients without comorbidities 33:59 The association between primary ovarian insufficiency and increased multimorbidity in a large prospective cohort (Canadian Longitudinal Study on Aging) 41:28 Target trial emulation of preconception serum vitamin D status on fertility outcomes: a couples-based approach 52:59 Predicting a successful match among applicants to reproductive endocrinology and infertility fellowship View Fertility and Sterility February 2025, Volume 123, Issue 2:https://www.fertstert.org/issue/S0015-0282(24)X0015-1 View Fertility and Sterility at https://www.fertstert.org/

Take a sneak peek at this month's Fertility and Sterility! Articles discussed this month are:   02:59 Preimplantation genetic testing for aneuploidy is associated with reduced live birth rates in fresh but not frozen donor oocyte in vitro fertilization cycles: an analysis of 18,562 donor cycles reported to Society for Assisted Reproductive Technology Clinic Outcome Reporting System 19:37 Sperm concentration remains stable among fertile American men: a systematic review and meta-analysis 26:02 Preovulation body mass index and pregnancy after first frozen embryo transfer in patients with polycystic ovary syndrome and insulin resistance 36:54 A retrospective comparison of the impact of industry payments on assisted reproductive technology practice and outcomes 44:55 Preimplantation genetic testing for aneuploidy in unexplained recurrent pregnancy loss: a systematic review and meta-analysis 61:03 Initiation and outcomes of women pursuing planned fertility preservation 65:49 First successful ovarian cortex allotransplant to a Turner syndrome patient requiring immunosuppression: broad implications   View Fertility and Sterility October 2025, Volume 123, Issue 1: https://www.fertstert.org/issue/S0015-0282(24)X0014-X View Fertility and Sterility at https://www.fertstert.org/

Take a sneak peek at this month's Fertility and Sterility! Articles discussed this month are:   01:48 Trustworthiness criteria for meta-analyses of randomized controlled studies: OBGYN journal guidelines 06:24 Playing the long game for reproductive rights 08:04 Limiting the number of fresh donor oocytes inseminated with sperm as a strategy to minimize supernumerary embryos 15:38 Effectiveness of degradable polymer film in the management of severe or moderate intrauterine adhesions (PREG-2): a randomized, double-blind, multicenter, stratified, superiority trial 26:37 Aneuploidy rates and likelihood of obtaining a usable embryo for transfer among in vitro fertilization cycles using preimplantation genetic testing for monogenic disorders and aneuploidy compared with in vitro fertilization cycles using preimplantation genetic testing for aneuploidy alone 38:13 Antimüllerian hormone levels are associated with time to pregnancy in a cohort study of 3,150 women 47:50 Racial disparities in the outcomes of euploid single frozen-thawed embryo transfer cycles – analysis of the Clinical Outcome Reporting System of the Society for Assisted Reproductive Technology 2016–2018 data 57:14 No association between celiac disease and female infertility: evidence from Mendelian randomization analysis   View Fertility and Sterility October 2024, Volume 122, Issue 6:  https://www.fertstert.org/issue/S0015-0282(24)X0013-8 View Fertility and Sterility at https://www.fertstert.org/  

Take a sneak peek at this month's Fertility and Sterility! Articles discussed this month are:   04:20 LGBTQ+ family building: progress but lots more to do/Therapeutic donor insemination for LGBTQ+ families: a systematic review 09:52 Confirmation and pathogenicity of small copy number variations incidentally detected via a targeted next-generation sequencing-based preimplantation genetic testing for aneuploidy platform 23:40 Trends and outcomes of fresh and frozen donor oocyte cycles in the United States 34:11 A survey study evaluating donor gamete utilization rates, patient satisfaction, and fertility treatment outcomes according to desired race and ethnicity 39:29 Racial and ethnic disparities in wait times for donor oocytes 41:16 Return rates and pregnancy outcomes after oocyte preservation for planned fertility delay: a systematic review and meta-analysis 49:23 Longer duration to optimal endometrial thickness in women with premature ovarian insufficiency is associated with clinical pregnancy rate in donor egg cycles 56:30 Feasibility and efficacy of a subcutaneous catheter for controlled ovarian stimulation 01:00:23 International Committee for Monitoring Assisted Reproductive Technology world report: assisted reproductive technology, 2015 and 2016 View Fertility and Sterility October 2024, Volume 122, Issue 5:  https://www.fertstert.org/issue/S0015-0282(24)X0012-6 View Fertility and Sterility at https://www.fertstert.org/

Take a sneak peek at this month's Fertility & Sterility! Articles discussed this month are:   03:06 Embryos derived from single pronucleus are suitable for preimplantation genetic testing 09:59 Clinical factors impacting microdissection testicular sperm extraction success in hypogonadal men with nonobstructive azoospermia 24:46 Educational gradients in the prevalence of medically assisted reproduction births in a comparative perspective 32:14 Minimum number of mature oocytes needed to obtain at least one euploid blastocyst according to female age in in vitro fertilization treatment cycles 40:02 In vitro fertilization and perinatal outcomes of patients with advanced maternal age after single frozen euploid embryo transfer: a propensity score-matched analysis of autologous and donor cycles 46:57 Imprinting disorders in children conceived with assisted reproductive technology in Sweden View Fertility and Sterility October 2024, Volume 122, Issue 4:  https://www.fertstert.org/issue/S0015-0282(24)X0010-2 View Fertility and Sterility at https://www.fertstert.org/  

Fertility and Sterility On Air brings you the best of ASRM 2024! In Part 1, our hosts bring you: in vitro maturation with Christian Kramme (1:40), uterine transplant data updates with Leigh Ann Humphries (9:21), novel characterization of ploidy abnormalities with Ludovica Picchetta (21:50), maternal age and euploid transfer success with Philip Romanski (24:45), ultrasound assessment of ovarian stiffness to evaluate reproductive aging with Elnur Babayev (32:45), cost effectiveness of PGT-A in good prognosis patients with Ariel Dunn and Josh Combs (42:33), long-term follow up of oocyte donors with Jerrine Morris (51:16), and combining platforms to improve identifiation of mosaic embryos with Christopher Weier (58:28). View Fertility and Sterility at https://www.fertstert.org/  

Fertility and Sterility On Air brings you the best of ASRM 2024! In Part 2, our hosts bring you: home semen testing with Dan Greenberg (0:40), state insurance mandates for fertility coverage with Adeola Adeyeye (7:13), resource utilization difference between programmed and natural transfers with Ben Peipert (12:23), patient perspectives on embryo donation with Deb Roberts (21:37), corpus lutea and preeclampsia risk after embryo transfer with David Huang (35:02), exercise during stimulation with Maren Shapiro (40:57), combination of letrozole and clomiphene with Rachel Mejia and Jessica Kresowik (49:07), the impact of Alabama's personhood bill with David Monroe (54:06), and embryo quality and polygenic risk with Jordan O'Donnell (58:40). View Fertility and Sterility at https://www.fertstert.org/  

Take a sneak peek at this month's Fertility & Sterility! Articles discussed this month are:   02:17 In vitro fertilization practice in patients with absolute uterine factor undergoing uterus transplant in the United States 21:22 Classification and treatment of vaginal strictures at the donor-recipient anastomosis after uterus transplant 31:18 Impact of time interval from cesarean delivery to frozen embryo transfer on reproductive and neonatal outcomes 37:37 Multiplexed serum biomarkers to discriminate nonviable and ectopic pregnancy 50:20 Urinary benzophenone-3 concentrations and ovarian reserve in a cohort of subfertile women 53:38 Assessment of pregnancy outcomes in donor oocyte thaw cycles comparing fresh embryo transfer to cryopreserved-thawed embryo transfer: a sibling oocyte study View Fertility and Sterility September 2024, Volume 122, Issue 3:https://www.fertstert.org/issue/S0015-0282(24)X0009-6 View Fertility and Sterility at https://www.fertstert.org/  

Take a sneak peak at this month's Fertility & Sterility! Articles discussed this month are:   04:19 Assessment of obstetric characteristics and outcomes associated with pregnancy with Turner syndrome 13:55 Effect of postthaw change in embryo score on single euploid embryo transfer success rates 22:38 Effectiveness of preconception weight loss interventions on fertility in women: a systematic review and meta-analysis 37:17 Functional evidence for two distinct mechanisms of action of progesterone and selective progesterone receptor modulator on uterine leiomyomas 43:47 Predicting risk of endometrial failure: a biomarker signature that identifies a novel disruption independent of endometrial timing in patients undergoing hormonal replacement cycles 54:28 Analysis of factors affecting the prognosis of patients with intrauterine adhesions after transcervical resection of adhesions 01:05:29 Effects of a eucaloric high-fat diet on anterior pituitary hormones and adipocytokines in women with normal weight View Fertility and Sterility August 2024, Volume 122, Issue 2: https://www.fertstert.org/issue/S0015-0282(24)X0008-4 View Fertility and Sterility at https://www.fertstert.org/  

Fertility and Sterility On Air brings you the best of ESHRE 2024! In Part 1, hosts Micah Hill, Paul Pirtea, and Kate Devine bring you: embryo reexpansion and live birth with Ibrahim Elkhatib (01:30), a discussion with the RBMO editor, Nick Macklon, and F&S editor, Kurt Barnhardt, about “IVF add-ons” (11:21), rescue in vitro maturation with Danilo Cimadomo (24:43), discussion with F&S On Air listener Elizabeth Glanville (31:38), one side of the debate on dual/double triggers with Raoul Orvieto (35:27), and cross-border reproductive care for same-sex male intended parents with Brent Monseur (48:59).  View Fertility and Sterility at https://www.fertstert.org/  

Fertility and Sterility On Air brings you the best of ESHRE 2024! In Part 2, hosts Micah Hill, Paul Pirtea, and Kate Devine bring you: progesterone levels in a randomized controlled trial with long-acting FSH with Annalisa Racca (01:19), live birth of day 7 embryo transfers with Marcela Colonge and Nicolas Garrido (10:57), an ICSI vs conventional IVF randomized controlled trial with Sine Berntsen and Nina la Cour Freiesleben (17:17), limitations of reporting mosaicism in PGT-A with Dhruti Barbariya and Antonio Capalbo (27:15), interview with ASRM president Paula Amato and president-elect Elizabeth Ginsburg (32:41), and ovarian aging with Kutluk Oktay (45:17).   View Fertility and Sterility at https://www.fertstert.org/  

Take a sneak peek at this month's Fertility & Sterility! Articles discussed this month are:   4:56 A pilot study to investigate the clinically predictive values of copy number variations detected by next-generation sequencing of cell-free deoxyribonucleic acid in spent culture media 18:17 The impact of microfluidics sperm processing on blastocyst euploidy rates compared with density gradient centrifugation: a sibling oocyte double-blinded prospective randomized clinical trial 25:20 Prediction of pregnancy-related complications in women undergoing assisted reproduction, using machine learning methods 40:36 The effect of laser-assisted hatching on vitrified/warmed blastocysts: the ALADDIN randomized controlled trial 50:49 Assessment of clinical pregnancies in up to eight ovarian stimulation with intrauterine insemination treatment cycles in those unable to proceed with in vitro fertilization 1:02:56 Comparative analysis of pregnancy outcomes in preimplantation genetic testing for aneuploidy and conventional in vitro fertilization and embryo transfer: a stratified examination on the basis of the quantity of oocytes and blastocysts from a multicenter randomized controlled trial 1:09:45 Predictive models of miscarriage on the basis of data from a preconception cohort study   View Fertility and Sterility July 2024, Volume 122, Issue 1: https://www.fertstert.org/issue/S0015-0282(24)X0006-0 View Fertility and Sterility at https://www.fertstert.org/  

Take a sneak peak at this month's Fertility & Sterility! Articles discussed this month are:   4:33 A randomized controlled trial to compare the live birth rate of the first frozen embryo transfer following the progestin-primed ovarian stimulation protocol vs. the antagonist protocol in women with an anticipated high ovarian response 20:24 Improved fertilization, degeneration, and embryo quality rates with PIEZO–intracytoplasmic sperm injection compared with conventional intracytoplasmic sperm injection: a sibling oocyte split multicenter trial 31:15 A comparison of pregnancy outcomes and congenital malformations in offspring between patients undergoing intracytoplasmic sperm injection and conventional in vitro fertilization: a retrospective cohort study 37:05 A follicular volume of >0.56 cm3 at trigger is the cutoff to predict oocyte maturity: a starting point for novel volume-based triggering criteria 47:35 Midluteal serum estradiol levels are associated with live birth rates in hormone replacement therapy frozen embryo transfer cycles: a cohort study 57:10 First pregnancy and live birth from ex vivo-retrieved metaphase II oocytes from a woman with bilateral ovarian carcinoma: a case report 1:00:56 Associations between race and ethnicity and perioperative outcomes among women undergoing hysterectomy for adenomyosis   View Fertility and Sterility June 2024, Volume 121, Issue 6: https://www.fertstert.org/issue/S0015-0282(24)X0005-9   View Fertility and Sterility at https://www.fertstert.org/  

Take a sneak peek at this month's Fertility and Sterility! Articles discussed this month are:  6:24 Iatrogenic and demographic determinants of the national plural birth increase 18:10 Comparison of outcomes between intracytoplasmic sperm injection and in vitro fertilization inseminations with preimplantation genetic testing for aneuploidy, analysis of Society for Assisted Reproductive Technology Clinic Outcome Reporting System data 24:54 Retrospective cohort study comparing the success of medical management of early pregnancy loss in pregnancies conceived with and without medical assistance 33:31 Association of duration of embryo culture with risk of large for gestational age delivery in cryopreserved embryo transfer cycles 38:32 Endometriosis diagnosed by ultrasound is associated with lower live birth rates in women undergoing their first in vitro fertilization/intracytoplasmic sperm injection treatment 47:29 Quantitative ultrasound measurement of uterine contractility in adenomyotic vs. normal uteri: a multicenter prospective study 53:13 Unhealthy air quality secondary to wildfires is associated with lower blastocyst yield 1:03:22 The American Society for Reproductive Medicine's new and more inclusive definition of infertility may conflict with traditional and conservative religious-cultural values  View Fertility and Sterility May 2024, Volume 121, Issue 5: https://www.fertstert.org/issue/S0015-0282(24)X0004-7 View Fertility and Sterility at https://www.fertstert.org/  

Take a sneak peak at this month's Fertility & Sterility! Topics this month include the use of ICSI (4:51), fertility treatments among reproductive-aged women after cancer (7:43), oxygen tension during in vitro maturation (18:45), international gestational surrogacy in the United States (30:31), the menstrual cycle and weekly and lunar rhythms (39:42), AMH predicts ovulation in women with PCOS treated with clomid and metformin (46:29), laparoscopic Davydov vs laparoscopic Vecchietti neovaginoplasty in women with Mayer-Rokitansky-Kuster-Hauser syndrome (58:32), and vNOTES retroperitoneal transient uterine artery occlusion (1:04:47). View Fertility and Sterility Volume 121, issue 4: https://www.fertstert.org/issue/S0015-0282(24)X0003-5 View Fertility and Sterility at https://www.fertstert.org/

Listen to this interview featuring Dr. Jeremy Applebaum, who recently published "Impact of coronavirus disease 2019 vaccination on live birth rates after in vitro fertilization"  Read the article  https://www.fertstert.org/article/S0015-0282(23)02029-0/abstract View Fertility and Sterility at https://www.fertstert.org/

Take a sneak peak at this month's Fertility and Sterility! Topics this month include the impact of COVID-19 vaccination on live birth rates after IVF (4:17), the "freeze-all" strategy in women with adenomyosis (13:47), the impact of adenomyosis on donor egg IVF cycles (24:54), ART associated risk factors for retained products of conception (30:00), the POPI-plus tool (38:14), the association between job control and time to pregnancy in a preconception cohort (49:10), and sperm retrieval outcomes of contralateral testis in men with nonobstructive azoospermia and unsuccessful unilateral microdissection testicular sperm extraction (58:30).  View Fertility and Sterility Volume 121, issue 3: https://www.fertstert.org/issue/S0015-0282(24)X0002-3 View Fertility and Sterility at https://www.fertstert.org/  

Listen to this interview featuring Dr. Papri Sarkar and Dr. Phillip Romanski, who discuss their recent article "Optimal antimüllerian hormone levels in oocyte donors: a national database analysis."  Read the article  https://www.fertstert.org/article/S0015-0282(23)01992-1/abstract  View Fertility and Sterility at https://www.fertstert.org/  

Take a sneak peek at this month's Fertility and Sterility! Topics this month include the optimal AMH level in oocyte donors (5:23), the role of the mean number of DNA breakpoints (MDB) in sperm DNA integrity and IVF outcomes (12:29), declining FET outcomes with increasing female BMI (22:38), higher live birth rates in normal BMI PGT-A FET cycles (30:33), the association between oocyte donors' or recipients' BMI with clinical outcomes (40:49), isthomocele and IVF success (48:05), and quantifying the variability in the assessment of reproductive hormone levels (56:29). View Fertility and Sterility Volume 121, issue 2: https://www.fertstert.org/issue/S0015-0282(23)X0017-X View Fertility and Sterility at https://www.fertstert.org/

We are all the product of a reproductive process, yet reproductive biology, or the study of the processes and mechanisms involved in reproduction, is not well understood. Deepening our understanding of reproductive biology is crucial to advancing assistive reproductive technologies (ART) and advancing our collective comprehension of inheritance and evolution. Our guests for this episode are a couple, and we mean a literal married couple, of reproductive biology experts. Dr. Pavla Brachova and Dr. Nehemiah Alvarez, both working in the Eastern Virginia Medical School's Department of Physiological Sciences. In their collaborative work they aim to better understand and characterize the role of RNA and cellular events that impact ovarian function in women. We learn about their work with oocytes, which are single cells that grow and mature within the ovary and once fertilized provide the foundations of an embryo capable of maturing to a new individual. They outline how they use digital PCR (dPCR) and other methods to monitor RNA regulation in single cells and how progressing this work and lead to potential RNA-based therapies. In Cassie's career corner we hear childhood stories from each guest and learn about their respective career paths, which eventually collided and merged. They share insights on the importance of having mentors experienced in your field, the challenges of shared job searching, and the joys of collaborating as a couple with shared scientific interests.Visit the Absolute Gene-ius page to learn more about the guests, the hosts, and the Applied Biosystems QuantStudio Absolute Q Digital PCR System. 

Take a sneak peak at this month's Fertility & Sterility! Topics this month include the association between thick endometrium with hypertensive disorders of pregnancy (3:40), state insurance mandates and racial ethnic inequities in ART (12:45), azoospermia factor c microdeletions and outcomes of art (18:20), sperm production in men with azoospermia factor c Y-chromosome microdeletions (25:51), orthotopic and heterotopic ovarian tissue transplantation outcomes (31:25), endocrine profile of the kisspeptin receptor agonist MVT-602 in healthy premenopausal women (38:33), and risk of hysterectomy at time of myomectomy (47:30).  View Fertility and Sterility Volume 121, issue 1: https://www.fertstert.org/issue/S0015-0282(23)X0016-8  View Fertility and Sterility at https://www.fertstert.org/  

Take a sneak peak at this month's Fertility & Sterility! Topics this month include rebiopsy and analysis of noneuploid embryos with 2 distinct PGT platforms (6:01), mobile phone use and semen quality (25:22), steroid use and fertility outcomes (33:54), estradiol levels during programmed frozen embryo transfer cycles (43:25), gender differences in letters of recommendation for REI fellowship (50:38) and hysteroscopic morcellation vs curettage for retained products of conception (1:02:57)  View Fertility and Sterility Volume 120, issue 6: https://www.fertstert.org/issue/S0015-0282(23)X0015-6 View Fertility and Sterility at https://www.fertstert.org/  

Take a sneak peek at this month's Fertility & Sterility! Topics this month include scientific integrity (1:59),  chromosomal, gestational, and neonatal outcomes of mosaic embryos (6:26), risk of congenital malformations after ICSI (15:15), successful cryptozoospermia management with multiple semen specimen collection (28:58), and fertility preservation in girls with Turner syndrome (39:03)  View Fertility and Sterility Volume 120, issue 5:  https://www.fertstert.org/issue/S0015-0282(23)X0014-4  View Fertility and Sterility at https://www.fertstert.org/  

Take a sneak peak at this month's Fertility & Sterility! Topics this month include whether sperm quality affects reproductive outcomes (2:20), CRISPR for human embryonic editing (6:00), the appropriate length of REI training (12:28), meeting the US demand for fertility services (14:44), testosterone and LH as predictors of semen parameter improvement in men treated with anastrazole (25:35), reproductive inequity and IUI outcomes in patients with limited English proficiency (41:33), the developmental potential of mature oocytes derived from rescue IVM (50:28), and trends in infertility prevalence and treatment seeking in the US (59:19).  View Fertility and Sterility Volume 120, issue 4:  https://www.fertstert.org/issue/S0015-0282(23)X0013-2  View Fertility and Sterility at https://www.fertstert.org/    

Take a sneak peak at this month's Fertility & Sterility! Topics this month include the promise and peril of using ChatGPT as a fertility counseling tool (5:55), the impact of elevated serum progesterone levels before FET on reproductive outcomes (21:10), Bologna vs Poseidon criteria as predictors of the likelihood of obtaining at least 1 euploid embryo in poor ovarian response (28:44), the association of environmental exposure with decreased male fertility, and oral vinorelbine to treat ectopic pregnancy (45:18).  View Fertility and Sterility Volume 120, issue 3: https://www.fertstert.org/issue/S0015-0282(23)X0011-9   View Fertility and Sterility at https://www.fertstert.org/  

Take a sneak peak at this month's Fertility & Sterility! Topics this month include the effect of maternal age on ART success rates after euploid embryo transfer (8:42), attachment of trophoblastic spheroid onto endometrial epithelial cells (18:25), antagonist protocol vs flare in poor responders (26:39), the association between dietary patterns and risk of miscarriage (37:32), and the assessment of foliiculogenesis in ovarian tissue from young patients with Turner syndrome (43:37).  View Fertility and Sterility Volume 120, issue 2: https://www.fertstert.org/issue/S0015-0282(23)X0009-0   View Fertility and Sterility at https://www.fertstert.org/  

Take a sneak peak at this month's Fertility & Sterility! Topics this month include the impact of socioeconomic factors on semen parameters (01:42), modified natural versus programmed embryo transfer cycles (09:45); gynecologic malignancy after treating fibroids with interventional radiology procedures (20:41); state insurance mandates on disparities on donor oocytes (28:35); vasectomy incidence rates after the reversal of Roe v. Wade (38:19). View Fertility and Sterility Volume 120, issue 1: https://www.fertstert.org/issue/S0015-0282(23)X0007-7  View Fertility and Sterility at https://www.fertstert.org/  

Fertility & Sterility comes to you from ESHRE 2023 in Copenhagen, Denmark! Listen in as we discuss some of the best abstracts from the conference. Topics include the composition of commercially available human preimplantation embryo culture media (Miriam Zagers - 01:12); a trial of intraovarian injection of platelet rich plasma for women with poor ovarian response (Nola Herlihy - 09:49); the diagnostic yield of custom-designed gene panel for patients with premature ovarian insufficiency (Asma Sassi - 18:06); a trial treating IVF patients with abnormal vaginal microbiome (Thor Haahr - 28:03); peri- and postnatal outcomes three years of life after the transfer of mosaic embryos (Ruth Morales - 36:33); a teen survey on sex and reproductive health education in the UK (Rina Biswakarma - 42:10); a comparison of fetal ploidy status in pregnancy loss evaluated by cell-free fetal DNA in maternal blood versus direct sequencing of the pregnancy tissue (Tanja Schlaikjær Hartwi - 48:12) and clustering identifies to establish distinct subtypes of PCOS (Kim van der Ham - 57:02) View Fertility and Sterility at https://www.fertstert.org/

Take a sneak peak at this month's Fertility & Sterility! Topics this month include a trial on maternal spindle transfer for recurrent implantation failure (02:38), progesterone rescue during embryo transfer (15:07), contraceptive-specific AMH (21:58), soy and ovarian reserve (33:20), micronutrient supplementation on time-to-conception and clinical pregnancy rate (38:08), effects of large, non-distorting fibroids (44:41) and a look at Letters to the Editor (52:30). View Fertility and Sterility Volume 119, issue 6: https://www.fertstert.org/issue/S0015-0282(23)X0006-5  View Fertility and Sterility at https://www.fertstert.org/  

This week we're talking about "advanced maternal age" which is the medical term for women having babies over the age of 35. The real problem here comes down to oocyte aging, or aging eggs, which is related to poor ovarian reserve. We'll talk about why egg quality declines with time, what sort of testing your doctor will run, the difference between poor ovarian reserve and advanced maternal age, the options for women trying to get pregnant, lifestyle and supplements for oocyte aging and to increase egg quality, and also advanced paternal age, or old sperm. 00:00 - Intro 00:28 - Why egg (oocyte) quality declines with time 03:07 - Testing for oocyte quality 04:56 - Poor ovarian reserve vs. advanced maternal age 06:57 - Options for women with oocyte aging 08:36 - Lifestyle and supplements for oocyte aging 11:11 - Advanced paternal age 13:49 - Outro Here's the video version of Dr. Kate and Dr. Amy talking this one through. If you're working on your health by balancing gene SNPs and epigenetics, join Genetic Rockstars. If you'd like to take a course on MTHFR, click here. To learn more about Dr. Kate Naumes, visit naumesnd.com. For more about Dr. Amy Neuzil, visit tohealthwiththat.com --- Send in a voice message: https://podcasters.spotify.com/pod/show/tohealthwiththat/message

Take a sneak peak at this month's Fertility & Sterility! Topics this month include the impact of genetics lab on euploid and live birth rates (01:58), pregnancy & neonatal outcomes after long-term vitrification (09:44), risk of hypertensive disorders of pregnancy in donated-embryos pregnancies (18:08), diagnosing ectopic pregnancy using Bayes theorem (25:42), markers of ovarian reserve as predictors of future fertility (34:36) and letrozole-induced ovulation in women with PCOS and letrozole resistance (40:46). View the January 2023 issue of Fertility and Sterility: Volume 119, No 1 - https://www.fertstert.org/issue/S0015-0282(22)X0004-6  View Fertility and Sterility at https://www.fertstert.org/

Take a sneak peak at this month's Fertility & Sterility! Topics this month include outcomes after intrauterine insemination in low AMH versus normal AMH women (2:57), impact of low initial serum hCGs after IVF pregnancies on pregnancy complications and placental pathology (18:23), single embryo transfer of good quality embryo versus double embryo transfer with 2nd poor-quality embryo (29:00), cardiometabolic health outcomes in fresh vs frozen embryo transfers (41:15), pathways of mTOR in primary ovarian insufficiency (52:36) and a review of surgery for endometriomas (56:58) View the December 2022 issue of Fertility and Sterility: Volume 118, No 6 - https://www.fertstert.org/issue/S0015-0282(21)X0026-X View Fertility and Sterility at https://www.fertstert.org/