Podcasts about Fertility preservation

In this episode, Terri Coutee, Founder and Director of DiepCFoundation, sits down with Dr. Priya Jadeja, board‑certified breast surgeon with Premier Surgical Network in New Jersey. Dr. Jadeja brings a powerful blend of clinical expertise, advocacy, and compassion to her work in this episode of the DiepCJourney® podcast, and she shares why fertility preservation must be part of comprehensive cancer care for young patients. Episode Highlights Dr. Jadeja's path to breast surgery She reflects on what drew her to the field and how joining Premier Surgical Network has strengthened her ability to deliver high‑quality, patient‑centered care. Why fertility preservation matters With more young women facing breast cancer diagnoses, Dr. Jadeja explains how fertility considerations became a defining part of her practice and why this issue is gaining national attention. A patient story that sparked change Dr. Jadeja discusses the moment a 32‑year‑old patient declined chemotherapy because fertility preservation was financially out of reach and a turning point that ignited her advocacy. Partnering with Assemblywoman Brittnee Timberlake Hear the behind‑the‑scenes journey of the New Jersey Fertility Preservation Law, including traveling to Trenton with her patient to support the bill. Dr. Jadeja shares what this experience meant to her personally and professionally. Fertility preservation as essential cancer care As a female breast surgeon caring for young women with highly treatable disease, Dr. Jadeja outlines why fertility must be integrated into treatment planning; not treated as an optional conversation. Legislation shaping the future of patient‑centered care With New York becoming the first state to mandate private insurance coverage for scalp cooling systems, Dr. Jadeja discusses what this signals about the evolving landscape of supportive cancer care. Advice for advocates and clinicians Dr. Jadeja offers guidance for anyone - surgeons, patients, caregivers, or advocates, who want to create legislative change and amplify patient voices. Where to Find Dr. Jadeja Follow Dr. Priya Jadeja on Instagram for accessible, educational content on breast cancer surgery, fertility preservation, and patient advocacy. Listen & Watch You can listen to DiepCJourney® Podcast on Spotify and Apple Podcasts and watch full episodes on the DiepCFoundation YouTube Channel when published.  

New gene therapies have changed what may be possible for some sickle cell patients. But providers say the path to treatment remains long, expensive and difficult to access.

If you're struggling with fertility, you have options. This week's guest is here to provide them. Dr. Jaime Knopman is a double board-certified OB/GYN and reproductive endocrinologist who serves as the National Director of Fertility Preservation for CCRM Fertility of New York and the Medical Director of The Chick Mission, a nonprofit supporting young adult cancer patients facing fertility challenges. She's also the author of Own Your Fertility: From Egg Freezing to Surrogacy, How to Take Charge of Your Body and Your Future. Hear how egg freezing technology & surrogacy have advanced in recent years, the history of egg freezing, what the costs look like for egg freezing & surrogacy, whether we can extend the life of ovaries, and the age she recommends freezing eggs. Tune in to this episode to help more mothers navigate fertility and benefit from egg freezing & surrogacy.   Learn more: Dr. Jaime Knopman CCRM Fertility of New York The Chick Mission   Today's Hot Flash and other stats from: Johns Hopkins Bloomberg School of Public Health

As colorectal cancer rates rise among younger adults, surgeons are increasingly caring for patients with rectal cancer who are pregnant or hoping to preserve future fertility. With more individuals delaying childbearing, balancing effective cancer treatment with fertility preservation and maternal–fetal safety has become an important clinical challenge. This timely topic was recently highlighted by Dr. Sharon Suwanabol during a presentation at the American Society of Colon and Rectal Surgeons annual meeting 2026. In this episode, we explore the intersection of rectal cancer, fertility, and pregnancy through a multidisciplinary, case-based discussion. We review how surgery, chemotherapy, and pelvic radiation can affect fertility and sexual function in both men and women, and why early counseling and referral to reproductive endocrinology specialists are essential. The discussion also emphasizes that evaluation and treatment during pregnancy can often be performed safely, with care individualized based on tumor stage, gestational age, and the patient's goals and values. Hosts and discussants ·      Dr. Betelhem Yohannes, General surgery resident at the University of Washington ·      Dr. Griffen Allen, General surgery resident at the University of Washington  ·      Dr. Raga Siddharthan, Assistant Professor of Surgery in the Section of Colorectal Surgery at the University of Washington  ·      Dr. Stacey Cohen, Professor in the Division of Hematology and Oncology at the University of Washington and a gastrointestinal medical oncologist at Fred Hutch Cancer Center, specializing in colorectal and other GI cancers. Learning objectives ·      Describe the impact of rectal cancer surgery on fertility, sexual function, and future childbearing potential. ·      Review the effects of chemotherapy and pelvic radiation on reproductive health and fertility preservation. ·      Discuss available fertility preservation strategies and the importance of early pre-treatment counseling and referral. ·      Recognize the diagnostic challenges of rectal cancer during pregnancy, including overlapping gastrointestinal symptoms. ·      Review appropriate staging and workup considerations for suspected rectal cancer in pregnant patients. ·      Discuss multidisciplinary management strategies for rectal cancer during pregnancy, including individualized treatment sequencing. ·      Examine ethical and patient-centered considerations when balancing maternal cancer treatment and fetal outcomes. References  Siegel RL, Wagle NS, Star J, Kratzer TB, Smith RA, Jemal A. Colorectal cancer statistics, 2026. CA Cancer J Clin. 2026;76(2):e70067. doi:10.3322/caac.70067 [https://pubmed.ncbi.nlm.nih.gov/38240409/] Pregnancy at Age 35 Years or Older: ACOG Obstetric Care Consensus No. 11. Obstet Gynecol. 2022;140(2):348-366. doi:10.1097/AOG.0000000000004873 [https://pubmed.ncbi.nlm.nih.gov/35640237/] Stal J, YI SY, Cohen-Cutler S, et al. Fertility Preservation Discussions Between Young Adult Rectal Cancer Survivors and Their Providers: Sex-Specific Prevalence and Correlates. Oncologist. 2022;27(7):579-586. doi:10.1093/oncolo/oyac052 [https://pubmed.ncbi.nlm.nih.gov/35708892/] Druvefors E, Myrelid P, Andersson RE, Landerholm K. Female and Male Fertility after Colectomy and Reconstructive Surgery in Inflammatory Bowel Disease: A National Cohort Study from Sweden. J Crohns Colitis. 2023;17(10):1631-1638. doi:10.1093/ecco-jcc/jjad079 [https://pubmed.ncbi.nlm.nih.gov/37341355/] Ito M, Tsukada Y, Watanabe J, et al. Long-term survival and functional outcomes of laparoscopic surgery for clinical stage I ultra-low rectal cancers located within 5 cm of the anal verge: A prospective phase II trial (Ultimate trial). Ann Surg. Published online April 1, 2024. doi:10.1097/SLA.0000000000006290 [https://pubmed.ncbi.nlm.nih.gov/38629555/] Teh WT, Stern C, Chander S, Hickey M. The impact of uterine radiation on subsequent fertility and pregnancy outcomes. Biomed Res Int. 2014;2014:482968.  Johnson GGRJ, Park J, Helewa RM, Goldenberg BA, Nashed M, Hyun E. Total neoadjuvant therapy for rectal cancer: a guide for surgeons. Can J Surg. 2023 Apr 21;66(2):E196-E201. doi: 10.1503/cjs.005822. PMID: 37085291; PMCID: PMC10125160. [https://pubmed.ncbi.nlm.nih.gov/37085291/] Naren G, Guo J, Bai Q, Fan N, Nashun B. Reproductive and developmental toxicities of 5-fluorouracil in model organisms and humans. Expert Rev Mol Med. 2022 Jan 31;24:e9. doi: 10.1017/erm.2022.3. PMID: 35098910; PMCID: PMC9884763. [https://pubmed.ncbi.nlm.nih.gov/35098910/] National Comprehensive Cancer Network. (2026). NCCN Clinical Practice Guidelines in Oncology: Rectal Cancer (Version 2.2026). Retrieved from NCCN Guidelines for Rectal Cancer [https://www.nccn.org/guidelines/guidelines-detail?category=1&id=1449] Oktay, Kutluk M.D., Ph.D.. Expert Commentary on Fertility Preservation in Colorectal Cancers: Current State and Practical Tips for the Cancer Practitioner. Diseases of the Colon & Rectum 63(6):p 726-727, June 2020. | DOI: 10.1097/DCR.0000000000001688 [https://pubmed.ncbi.nlm.nih.gov/32479532/] Stal J, YI SY, Cohen-Cutler S, et al. Fertility Preservation Discussions Between Young Adult Rectal Cancer Survivors and Their Providers: Sex-Specific Prevalence and Correlates. Oncologist. 2022;27(7):579-586. doi:10.1093/oncolo/oyac052 [https://pubmed.ncbi.nlm.nih.gov/35708892/] Gentile G, Ciccarone M. Management of fertility preservation in young female patients with gastrointestinal cancer: A case series and systematic literature review. Curr Probl Cancer. 2025;57:101221. doi:10.1016/j.currproblcancer.2025.101221 [https://pubmed.ncbi.nlm.nih.gov/39598263/] Saif MW. Management of colorectal cancer in pregnancy: a multimodality approach. Clin Colorectal Cancer. 2005;5(4):247-256. doi:10.3816/ccc.2005.n.035 [https://pubmed.ncbi.nlm.nih.gov/16183863/] Rogers JE, Dasari A, Eng C. The Treatment of Colorectal Cancer During Pregnancy: Cytotoxic Chemotherapy and Targeted Therapy Challenges. Oncologist. 2016 May;21(5):563-70. doi: 10.1634/theoncologist.2015-0362. Epub 2016 Mar 21. PMID: 27000464; PMCID: PMC4861360. [https://pubmed.ncbi.nlm.nih.gov/27000464/] Jiang Q, Hua H. Fertility in young-onset colorectal patients with cancer: a review. Oncologist. 2024;29(10):e1237-e1245. doi:10.1093/oncolo/oyae141 [https://pubmed.ncbi.nlm.nih.gov/39292850/] Dolmans MM, Hollanders de Ouderaen S, Demylle D, Pirard C. Utilization rates and results of long-term embryo cryopreservation before gonadotoxic treatment. J Assist Reprod Genet. 2015;32(8):1233-1237. doi:10.1007/s10815-015-0533-z [https://pubmed.ncbi.nlm.nih.gov/26162569/ Moawad NS, Santamaria E, Rhoton-Vlasak A, Lightsey JL. Laparoscopic Ovarian Transposition Before Pelvic Cancer Treatment: Ovarian Function and Fertility Preservation. J Minim Invasive Gynecol. 2017;24(1):28-35. doi:10.1016/j.jmig.2016.08.831 [https://pubmed.ncbi.nlm.nih.gov/27599763/] Fish R. Ovarian transposition in rectal cancer: uncertain benefit at a high price. Colorectal Dis. 2022;24(6):706-707. doi:10.1111/codi.16086 [https://pubmed.ncbi.nlm.nih.gov/35191146/] Ribeiro R, Baiocchi G, Moretti-Marques R, Linhares JC, Costa CN, Pareja R. Uterine transposition for fertility and ovarian function preservation after radiotherapy. Int J Gynecol Cancer. 2023;33(12):1837-1842. Published 2023 Dec 4. doi:10.1136/ijgc-2023-004723 [https://pubmed.ncbi.nlm.nih.gov/38104863/] Haggar F, Pereira G, Preen D, et al. Maternal and neonatal outcomes in pregnancies following colorectal cancer. Surg Endosc. 2013;27(7):2327-2336. doi:10.1007/s00464-012-2774-6 [https://pubmed.ncbi.nlm.nih.gov/23645367/] Please visit https://behindtheknife.org to access other high-yield surgical education podcasts, videos and more.  If you liked this episode, check out our recent episodes here: https://behindtheknife.org/listenBehind the Knife Premium: https://behindtheknife.org/premiumOral Board Review: https://behindtheknife.org/oral-boardOral Board Simulator: https://behindtheknife.org/oral-board/simulatorGeneral Surgery Oral Board Review Course: https://behindtheknife.org/premium/general-surgery-oral-board-reviewTrauma Surgery Video Atlas: https://behindtheknife.org/premium/trauma-surgery-video-atlasDominate Surgery: A High-Yield Guide to Your Surgery Clerkship: https://behindtheknife.org/premium/dominate-surgery-a-high-yield-guide-to-your-surgery-clerkshipDominate Surgery for APPs: A High-Yield Guide to Your Surgery Rotation: https://behindtheknife.org/premium/dominate-surgery-for-apps-a-high-yield-guide-to-your-surgery-rotationVascular Surgery Oral Board Review Course: https://behindtheknife.org/premium/vascular-surgery-oral-board-reviewColorectal Surgery Oral Board Review Course: https://behindtheknife.org/premium/colorectal-surgery-oral-board-reviewSurgical Oncology Oral Board Review Course: https://behindtheknife.org/premium/surgical-oncology-oral-board-reviewCardiothoracic Oral Board Review Course: https://behindtheknife.org/premium/cardiothoracic-surgery-oral-board-reviewDownload our App:Apple App Store: https://apps.apple.com/us/app/behind-the-knife/id1672420049Android/Google Play: https://play.google.com/store/apps/details?id=com.btk.app&hl=en_US

Love the podcast? Send us a text!When you're diagnosed with breast cancer, your first thought is often survival.But what about everything that comes after?For many young adults diagnosed with breast cancer, questions about fertility, family planning, hormone health, identity, and future possibilities quickly become part of the conversation. Yet too many patients never learn about their options until after treatment has already begun.In this episode of Breast Cancer Conversations, Laura Carfang sits down with Kara Bendle, RN, MSN, CPN, CNL, Fertility Preservation and Adolescent & Young Adult (AYA) Program Manager at Cleveland Clinic, to discuss why fertility conversations matter from the very beginning of a cancer diagnosis.Together, they explore:• When fertility preservation conversations should happen• How breast cancer treatments can affect fertility and hormone health• The difference between fertility preservation and family building• Egg freezing, embryo preservation, and ovarian tissue preservation• The emotional impact of infertility and loss of choice• Dating, relationships, and family planning after cancer• Fertility considerations for hormone-positive breast cancer patients• Insurance barriers and access to care• Why patients deserve information—even when options are limited• The importance of keeping future possibilities openThis conversation goes far beyond fertility. It explores identity, grief, survivorship, and the power of informed decision-making after a breast cancer diagnosis.Whether you are newly diagnosed, in treatment, navigating survivorship, or supporting someone you love, this episode offers compassionate and practical guidance for understanding your options and advocating for your future.Love this episode? Send us a text through the link in the show notes. Messages are completely anonymous. If you'd like a response, include your email address so we can follow up directly.Support the showListener FeedbackIf this episode resonated with you, we invite you to leave a review on Apple Podcasts or Spotify.You can also click the link in the show notes that says "Love this episode? Send us a text" to share feedback.Messages are completely anonymous.If you would like us to follow up directly, please include your email address in your message so we can respond.Latest News: Join our Mailing List - New content drops every Monday! Discover FREE programs, support groups, and resources from SurvivingBReastCancer.org! Become a Breast Cancer Conversations+ Member! Sign Up Now. Enjoying our content? Please consider supporting our work. 

Ann & Robert H. Lurie Children's Hospital of Chicago is celebrating a multimillion-dollar donation that will help advance fertility and hormone preservation research. The $3 million gift to the hospital's Stanley Manne Children's Research Institute comes from the Mary and Ralph Gesualdo Family Foundation. $2 million will be used to directly support key research initiatives, and the remaining $1 million will establish the Gesualdo Family Research Scholar which will be an endowed position supporting the recruitment of a PhD scientist who is dedicated to advancing research in the field of fertility and hormone preservation and restoration.

Ann & Robert H. Lurie Children's Hospital of Chicago is celebrating a multimillion-dollar donation that will help advance fertility and hormone preservation research. The $3 million gift to the hospital's Stanley Manne Children's Research Institute comes from the Mary and Ralph Gesualdo Family Foundation. $2 million will be used to directly support key research initiatives, and the remaining $1 million will establish the Gesualdo Family Research Scholar which will be an endowed position supporting the recruitment of a PhD scientist who is dedicated to advancing research in the field of fertility and hormone preservation and restoration.

Ann & Robert H. Lurie Children's Hospital of Chicago is celebrating a multimillion-dollar donation that will help advance fertility and hormone preservation research. The $3 million gift to the hospital's Stanley Manne Children's Research Institute comes from the Mary and Ralph Gesualdo Family Foundation. $2 million will be used to directly support key research initiatives, and the remaining $1 million will establish the Gesualdo Family Research Scholar which will be an endowed position supporting the recruitment of a PhD scientist who is dedicated to advancing research in the field of fertility and hormone preservation and restoration.

Did you know that by age 32, women may have already lost up to 90% of their eggs? For decades, women have been told they can “have it all” — career success, love, family, and freedom. But few are told how fertility and biology truly fit into that equation.In this powerful and eye-opening episode of Women Road Warriors, Shelley Johnson and Kathy Tuccaro welcome leading reproductive endocrinologist Dr. Jaime Knopman, Director of Fertility Preservation at CCRM New York, and co-author of the new book Own Your Fertility: From Egg Freezing to Surrogacy, How to Take Charge of Your Body and Your Future.Dr. Knopman breaks down what every woman needs to understand about fertility, infertility, egg freezing, delayed motherhood, reproductive health, and the biological clock. She challenges the myths and misinformation surrounding women's fertility and explains why understanding your options earlier can empower women to make informed decisions without fear, shame, or regret.A nationally recognized fertility expert, cancer survivor, and mother of two, Dr. Knopman has been featured in Oprah Daily, Vogue, Women's Health, Wired, NBC News, and more.In this episode, learn: • Why fertility is not fair to women • What causes infertility • The myths surrounding infertility and egg freezing • What women should know before delaying motherhood • The reality of the biological clock • Fertility preservation and reproductive options• Workplace options that may pay for the freezing of eggs• The emotional and cultural pressure surrounding “having it all” • Why women deserve honest fertility education earlier in lifeIf you are thinking about motherhood now or in the future or simply want honest information about women's health and fertility, this conversation could change the way you think about your future.www.drjaimeknopman.comwww.womenroadwarriors.comwww.womenspowernetwork.net#Fertility #EggFreezing #Infertility #WomensHealth #BiologicalClock #ReproductiveHealth #DelayedMotherhood #FertilityAwareness #DrJaimeKnopman #ShelleyJohnson #KathyTuccaro #WomenRoadWarriors

WOMEN DOING AMAZING THINGS✨ In this episode, we welcome Dr. Jaime Knopman. Dr. Knopman is helping redefine how women approach their reproductive health, making fertility conversations more accessible, informed, and empowering. She brings clarity to decisions that can often feel overwhelming, while helping women feel confident in their choices.Today, Dr. Knopman is the Director of Fertility Preservation at CCRM Fertility of New York and is the co-author of Own Your Fertility, a modern guide giving women the tools to take control of their futures. Tune in to hear her insights and advice for the next generation of female leaders

In this episode of Better Edge, Robert Brannigan, MD, president of the American Society for Reproductive Medicine (ASRM), discusses key updates from ASRM's 2026 committee opinion on fertility preservation. Dr. Brannigan outlines what urologists should know about early identification, rapid referral, preservation options across adult and pediatric populations, documentation requirements and barriers to access. The conversation focuses on practical workflow considerations and how urologists can better support patients facing fertility threatening therapies.

Fertility preservation is changing how we think about family planning.  In this episode, Sonia Azad sits down with fertility specialist Dr. Katie Doody to explore the evolving world of reproductive health and the options available today. We break down egg freezing vs embryo freezing— what it means, how it works, and what to consider. You'll learn: • The difference between egg freezing and embryo freezing • How age impacts fertility and outcomes • What the process actually looks like (timeline, injections, retrieval) • Common myths about fertility preservation • How technology is changing success rates • What to consider when planning for your future family Subscribe for more conversations on health, wellness, and life transitions. Chapters: 00:00 Introduction 01:00 Meet Dr. Katie Doody 02:30 Fertility vs Infertility (Why language matters) 04:00 Who seeks fertility treatment today? 06:00 Age, health, and fertility factors 09:20 How fertility technology has evolved 11:50 Egg Freezing vs Embryo Freezing 14:20 What the egg freezing process is really like 17:30 How many eggs do you actually need? 20:00 Success rates explained 21:30 Choosing between eggs vs embryos 24:00 GLP-1s, weight, and fertility 28:00 Future of fertility technology 30:00 Common myths about egg freezing 32:00 Different paths to building a family 34:00 Final thoughts Key Takeaways: Fertility preservation is not a guarantee, but it increases options Egg freezing and embryo freezing follow the same initial process Age impacts egg quality more than quantity You don't need a partner to start planning your future family Technology is improving success rates, but expectations matter There are multiple paths to building a family 

Welcome to Fertility & Sterility Roundtable, hosted by Dr. Emily Barnard and Dr. Ben Peipert! Each week, we will host a discussion with the authors of "Views and Reviews" and "Fertile Battle" articles published in a recent issue of Fertility & Sterility.  Today, we will be discussing a challenge that all of us in the field of reproductive medicine face, ovarian aging. We will specifically be discussing the Views and Reviews article from the March 2026 edition of Fertility and Sterility entitled "Influencing ovarian aging in reproductive medicine: promise, evidence, and unresolved questions." We are joined by three of the esteemed authors of this publication to dive into this topic, learn about new research, and sort out what treatments are and are not yet ready for prime time use in clinical practice.  Dr. Kara Goldman is a reproductive endocrinologist and Associate Professor of Obstetrics and Gynecology at Northwestern University, where she serves as Director of Fertility Preservation. Dr. Goldman leads a high-volume clinical program in complex fertility preservation, and her translational research focuses on the role of mTOR signaling in ovarian aging and strategies to preserve ovarian function during cancer treatment and physiologic aging. Her work led to several landmark publications and Prize Paper Awards from the American Society for Reproductive Medicine; she also serves on the editorial board of Fertility and Sterility. Dr. Francesca Duncan is an Associate Professor of Obstetrics and Gynecology at the Feinberg School of Medicine at Northwestern University. She co-directs Northwestern's Center for Reproductive Science and leads a research program focused on the cellular mechanisms of reproductive aging, studying how aging affects reproductive potential at the level of the egg and ovary. Over her career, she has co-authored numerous, and her research has been widely featured in several major news outlets including National Geographic, the New York Times, and the Wall Street Journal.  Dr. Allison Eubanks is a REI fellow in the NIH–Walter Reed training program and currently serves as the Fertility and Sterility Editorial Board Fellow. She is an active-duty U.S. Navy physician. Her work spans research across all aspects of reproductive endocrinology and infertility from ART to menopause, along with education and policy initiatives aimed at improving women's health and reproductive care across the military health system.   Read the Fertile Battle from Volume 125, Issue 3 p387-398 in the March 2026 issue View Fertility and Sterility at https://www.fertstert.org/

Today's guests are Megan and Mike Scherer, co-founders of Worth the Wait, a nationwide oncofertility non-profit organization. After Mike's experience as a testicular cancer survivor and their own fertility issues, they wanted to offer hope and resources for others navigating the world of oncofertility. Worth the Wait's mission is to empower young adult cancer survivors on their path to parenthood. They provide financial support and educational resources for fertility treatments, adoption, and surrogacy while advocating for oncofertility within the healthcare system and beyond.Having both Mike and Megan as guests, we talk about cancer from both the patient and caregiver perspective, fertility issues from reproductive cancers, the families Worth the Wait has helped build, making their mission a family affair with their son Elliott, and so much more!!!This is a conversation that should happen so much more, especially in the young adult cancer space. Please share with those in your life that may be dealing with oncofertility concerns.Resources:Website: https://worththewaitcharity.com/Instagram: https://www.instagram.com/worththewaitcharity/Facebook: https://www.facebook.com/WorthTheWaitCharityLinkedIn: https://www.linkedin.com/company/79794452/Megan's LinkedIn: https://www.linkedin.com/in/meganscherer/Mike's LinkedIn: https://www.linkedin.com/in/mike-schererwtw/Follow:Follow me: https://www.instagram.com/melissagrosboll/My website: https://melissagrosboll.comEmail me: drmelissagrosboll@gmail.com

When to test, how to prevent, and what you need to know about hereditary gynecologic cancer syndromes. Two USC gynecologic oncologists, Dr. Mona Guo and Dr. Marcia Ciccone, go in-depth in this BackTable OBGYN x Tumor Board crossover episode. --- Get the BackTable app https://www.backtable.com/app --- Timestamps 00:00 - Introduction01:37 - Why Hereditary Cancer Matters04:51 - Family History Red Flags09:01 - Who Should Order Genetic Testing11:32 - Variants and Counseling Pitfalls13:30 - Access and Remote Testing Options19:27 - BRCA1 Positive Patient Walkthrough24:52 - Risk-Reducing Surgeries29:11 - Prevention and Screening Limits32:38 - Why Ovarian Cancer Is Hard34:04 - Combining Breast and Gyn Surgery35:41 - Preop Ultrasound and CA-12536:27 - BRCA Timing and HRT Nuance42:32 - Nonhormonal Menopause Options47:14 - Lynch Syndrome Screening Basics54:22 - Endometrial Biopsy Debate56:43 - Insurance and Coverage Pitfalls59:00 - Fertility Preservation and REI01:01:41 - Cascade Testing01:02:45 - Conclusion --- More about this episode Dr. Guo and Dr. Ciccone discuss how careful family history can identify patients who may benefit from genetic evaluation and highlight key red flags, including a family history of ovarian cancer, breast cancer at age 50 or younger, and metastatic prostate cancer. They explain the role of genetic counseling, including pre- and post-test discussions and how to approach variants of uncertain significance. They then cover BRCA counseling and risk-reduction strategies, including the timing of risk-reducing bilateral salpingo-oophorectomy, ongoing salpingectomy trials, and considerations for hysterectomy. Additionally, they touch on pathology protocols, breast cancer screening, and the potential protective effect of hormonal contraception. The doctors address the limitations of ovarian cancer screening and outline patterns suggestive of Lynch syndrome, such as endometrial cancer occurring alongside gastrointestinal or urinary tract cancers. They review the Lynch workup, including tumor mismatch repair immunohistochemistry and MLH1 hypermethylation testing. Finally, they discuss practical considerations like barriers to access, Medicare coverage challenges, fertility preservation referrals, menopause management, and cascade testing in families, including the timing of testing in children. --- Resources NCCN Guidelines: Detection, Prevention, and Risk Reductionhttps://www.nccn.org/guidelines/category_2

In this episode Yoetzet Halacha Lisa Septimus and Dr. Joshua Klein discuss the benefits and challenges of fertility preservation, for both single and married women.   Note: If you are considering or planning fertility preservation and have any halachic questions, don't hesitate to reach out to a Nishmat Yoetzet Halacha Fertility Counselor either at https://www.yoatzot.org/about-yoatzot-halacha/fertility-counselors/ or on WhatsApp at +972-2-640-4330.

What does it really mean to own your fertility? In this episode, we're joined by Dr. Jaime Knopman from CCRM Fertility of New York and author of Own Your Fertility, for a candid conversation about egg freezing, fertility preservation, and grief. Dr. Knopman shares what inspired her to write the book, who it's for, and why fertility preservation can be one of the first acts of agency in reproductive health. We unpack common misconceptions about egg freezing. The conversation also turns to a topic often left unspoken: fertility-related grief. Dr. Knopman reflects on how grief shows up when timelines shift and how patients can hold both hope and loss at the same time. This episode is for anyone navigating fertility decisions, questioning timing, or seeking clarity and compassion along the journey. Own Your Fertility is now available on Amazon! Guest: Dr. Jaime Knopman, Board-Certified Reproductive Endocrinologist and Director of Fertility Preservation for CCRM Fertility of New York Hosts:  Dr. Janet Choi, Chief Medical Officer, Progyny Lissa Kline, LCSW, SVP, Provider and Member Services, Progyny --- For more information, visit Progyny's Education page. This show does not constitute medical advice. Be sure to follow us on Instagram, @progynyinc, and subscribe to our YouTube channel for more resources.   Music: YH1DOJKVSNXFR8GG (00:00) - Intro (01:58) - Why egg freezing and grief? (02:26) - Fertility preservation and egg freezing (05:06) - What is a good age to freeze eggs? (07:04) - If I freeze my eggs am I losing eggs? (08:55) - Egg freezing and birth control (09:30) - Breast cancer and fertility preservation (10:00) - Grief and family building (13:28) - The role of partners and community in family building (15:06) - Dr Knopman's Book! (16:12) - Fertility benefits create better outcomes (18:22) - Resilience (00:00) - Chapter 13 (00:00) - Chapter 14

In this episode, Dr. Randi Goldman, Associate Professor at Hofstra/Northwell and Program Director for the Reproductive Endocrinology and Infertility Fellowship, discusses how Northwell Health is scaling fertility preservation and oncofertility pathways. She shares strategies for improving patient access, coordinating care across specialties, and using data to drive outcomes and innovation in reproductive health.

Join me and my guest Jamie Knopman, MD, a board certified reproductive endocrinologist and Director of Fertility Preservation for CCRM Fertility of New York. She is also Assistant Clinical Professor in Obstetrics and Gynecology at Mount Sinai Hospital. We explore the intersection of fertility, career-building, and personal agency and why equitable access to egg freezing is essential to gender equality in the workplace and beyond. Jamie brings not only deep clinical expertise, but also a culturally sharp, unapologetically feminist perspective on why women shouldn't have to choose between thriving professionally and preserving their future ability to have children. Nearly 70% of her patients today are freezing eggs before they face infertility. And companies such as Meta, Disney, and Amazon often cover the cost. She also highlights new pathways like egg-sharing programs that allow women to preserve their fertility at no cost, if they choose to donate a portion of their eggs. These trends reflect a cultural shift, and one she believes we urgently need to accelerate. SHOW NOTES  SPONSORED BY: Power of You! https://leader.blainebartlett.com/power-of-you Summary In this conversation, Blaine and Dr. Jamie Knopman discusses the evolving landscape of fertility, particularly focusing on egg freezing and embryo preservation. She highlights the importance of education and empowerment for women in making informed choices about their reproductive health. The discussion also touches on the emotional dynamics surrounding fertility, the role of companies in supporting women's choices, and future innovations in fertility medicine. Dr. Knopman emphasizes the need for a supportive work environment that recognizes the unique challenges women face in balancing career and family planning.   Takeaways The shift from infertility to fertility preservation is significant. Egg freezing allows women to maintain reproductive autonomy. Companies are increasingly offering fertility benefits to attract talent. Emotional dynamics play a crucial role in fertility decisions. Work-life balance requires planning and support systems. Education about fertility is essential for informed choices. Women are empowered to take charge of their reproductive health. Future innovations in fertility medicine are promising. The journey of life is fluid and not linear. Supportive work environments enhance women's contributions. Learn more about your ad choices. Visit megaphone.fm/adchoices

In today's episode of Health Youniversity, we're exploring one of the most empowering decisions women can make for their reproductive future: fertility preservation through egg freezing.Join Dr. Susan as she sits down with Dr. Jamie Knopman, board-certified reproductive endocrinologist and co-author of the upcoming book "Own Your Fertility: From Egg Freezing to Surrogacy, How to Take Charge of Your Body and Your Future." Dr. Knopman serves as Director of Fertility Preservation for CCRM Fertility of New York and is a leading advocate for women's reproductive health education.Dr. Knopman shares why egg freezing is "the new sunscreen"—a preventative measure that gives women control over their reproductive timeline. She explains the ideal age to freeze eggs (hint: it's younger than you think), debunks common myths about the birth control pill and fertility, and reveals how the vitrification process has revolutionized success rates since 2011.This conversation covers the complete egg freezing process from start to finish, the recovery timeline, how employee benefits are changing to support fertility preservation, and why reproductive health education should start as early as high school. Dr. Knopman also discusses fertility planning for LGBTQ+ couples, the importance of understanding your menstrual cycle, and how egg freezing fits into the broader picture of reproductive rights and body autonomy.This episode is for you if if you're in your 20s or early 30s planning your career and future family, considering egg freezing but unsure where to start, working in HR and evaluating fertility benefits for employees, part of the LGBTQ+ community exploring family-building options, a parent wanting to educate your daughters about reproductive health, or a healthcare professional seeking to better counsel patients on fertility preservation.Pre-order "Own Your Fertility: From Egg Freezing to Surrogacy, How to Take Charge of Your Body and Your Future" Available on Amazon: https://www.amazon.com/Own-Your-Fertility-Freezing-Surrogacy/dp/1324111488] Barnes & Noble: https://www.barnesandnoble.com/w/own-your-fertility-jaime-knopman/1147402776 Audible:

Hello 2026!  What is going on for the future of conception, pregnancy, & healing birth loss? Are you open to your instincts from conception into motherhood?  What is next for the future of your babies? What do spirit babies have to say about building their own existence, communication, and this earth realm? Join the Spirituality Is Motherhood - only $37 monthly membership - HERE  Join Monthly (JAN 22) - Natural Conception Circle - HERE Ebook /paperback version Notes From A Spirit Baby Medium BUY- AMAZON-https://tinyurl.com/spiritbabymedium Notes From A Spirit Baby Medium- Everything you need to know about spirit baby communication This book is a spiritual guide for parents-to-be, parents, birth professionals, midwives, doulas, therapists, counselors, healers, as well as fertility and pregnancy coaches. It is for those who want to bring a new evolved understanding to how we conceive through the physical, energetic, emotional, and spiritual self with spirit baby communication. Ebook /paperback version Notes From A Spirit Baby Medium BUY- AMAZON- https://tinyurl.com/spiritbabymedium IngramSparks - Global book distributor - BUY- HERE https://shop.ingramspark.com/b/084... https://www.newearthchildren.com/note.... The New Earth Children are asking you to show up and own your power, release weaknesses, and align with your co-creative energy into the true Frequency of Love. Let the mission find you and know it is your time of great expansion. You are the leader to your inner guidance. You are entering healing and parenting in a new and evolved way forward. Instagram: @spiritbabymediumFacebook: Spirit Baby Medium/Medical IntuitiveFacebook: SPIRIT BABIES: Conscious Conception, Intuitive Pregnancy, & MotherhoodFacebook: The After Life of Spirit Baby- Healing, Connections,& LoveTwitter: @SPIRITBABYRADIO YouTube:    / @spiritbabycommunication    

This episode marks a powerful full-circle moment on Motherhood Intended.Three years ago, Alison joined the podcast to share her decision to freeze her eggs in an episode titled “Egg Preservation: A Story of 10 Maybe Babies.” At the time, she was preserving her fertility and creating options for her future — without knowing exactly where the journey would lead.Today, Alison is back to share what happened next.In this Season 7 premiere, Jacqueline and Alison reflect on the path from egg freezing to single motherhood by choice, including:deciding to pursue motherhood on her ownchoosing a sperm donorpursuing IVFnavigating pregnancy after infertility decisionsand welcoming her now almost six-month-old sonThis honest conversation explores both the emotional and practical sides of fertility preservation — from the uncertainty of freezing eggs to the realities of IVF, pregnancy, and early motherhood. Alison shares what surprised her most, what she wishes she had known earlier, and how she defines success now, looking back on the journey.This episode is for anyone who:is considering freezing their eggsis navigating fertility timelines or delayed parentingis exploring single motherhood by choiceor is wondering how today's fertility decisions can shape tomorrow's possibilitiesIt's a story about options, agency, patience — and what can unfold when you give yourself time.Stay ConnectedJacqueline will be hosting both in-person and virtual meet-ups in the coming months and sharing updates about Your Fertility Village! To stay in the loop, join her email list here: https://motherhoodintended.kit.com/Support the show__________________________________________________________________________________

Fertility is often treated like a guarantee until it isn't.I wanted this conversation because I see so many women doing everything “right” in life, only to feel blindsided when fertility doesn't align with their timeline. We talk about why fertility is not one thing, how egg quality and quantity change over time, and why having regular cycles doesn't always mean fertility is intact. We also unpack what egg freezing actually offers, who it's for, and how modern fertility care has expanded options far beyond what most of us were taught. Episode Timeline: 00:00 – Episode Preview01:31 – Podcast Intro02:05 – Queen of Egg Freezing03:12 – Career vs Fertility Timing03:56 – Ideal Egg Freezing Age05:24 – Egg Quality Matters Most06:19 – Pregnancy After Menopause07:19 – Be Your Own Egg Donor08:44 – Why Egg Freezing Surged10:02 – Fertility at 40 Myth11:43 – Lifestyle Guilt Explained15:06 – IVF Lab Quality Matters18:40 – IVF Emotional Toll21:33 – Fertility Myths Unlearned23:04 – Fertility Is Inefficient24:59 – Own Your Fertility Book28:20 – Motherhood Looks Different32:16 – Where to Find Dr. JamieAbout Dr. Jaime Knopman: Is a double board-certified reproductive endocrinologist, Director of Fertility Preservation at CCRM Fertility New York, and author of the forthcoming book Own Your Fertility: From Egg Freezing to Surrogacy, How to Take Charge of Your Body and Your Future, (Countryman Press, Jan 13th, 2026). Known nationally as the “Queen of Egg Freezing,” Dr. Knopman's approach to reproductive care is both scientific and radically human; she's on a mission to help women understand the real biological and hormonal shifts that affect fertility, including the one almost no one talks about: perimenopause.Connect with Dr. Jaime Knopman: Instagram - https://www.instagram.com/drjaimeknopman/ Website - https://www.ccrmivf.com/fertility/ Get Dr. Jaime Knopman's book at - https://www.amazon.com/Own-Your-Fertility-Freezing-Surrogacy/dp/1324111488 Links:Book a Hormone Breakthrough Call - https://calendly.com/briatheperiodwhisperer/private-coaching?month=2025-12 Connect with Bria on Instagram: https://www.instagram.com/bria_period_whisperer/ Learn more about Bria's coaching program: https://www.briatheperiodwhisperer.com/Coaching Subscribe to The Period Whisperer Podcast - https://podcasts.apple.com/us/podcast/the-period-whisperer-podcast-perimenopause-menopause/id1617315546 Spotify - https://open.spotify.com/show/5w8w0KbRuDwOUoBMzeFOOO YouTube - https://www.youtube.com/@bria_period_whisperer

Who should consider fertility preservation, when is the right time, and what are the risks? In this episode of BackTable OBGYN, Dr. Amy Park interviews Dr. Mindy Christianson, the section head of Reproductive Endocrinology and Infertility at the Cleveland Clinic, who shares how fertility preservation is evolving for patients planning families and those facing fertility-impacting treatments. --- SYNPOSIS Dr. Christianson discusses her journey into the field of fertility preservation, inspired by an early encounter with a breast cancer patient. The conversation covers various aspects of fertility preservation, including the preservation of eggs, embryos, ovarian and testicular tissue, and planned fertility preservation. Dr. Christianson elaborates on the protocols, patient demographics, and the evolving collaboration between oncology and reproductive endocrinology. The discussion also highlights technologies like ovarian tissue transplantation and in vitro maturation, as well as practical tips for healthcare providers on improving patient access to fertility preservation services. --- TIMESTAMPS 00:00 - Introduction03:34 - Understanding Fertility Preservation07:56 - Consultation Process for Fertility Preservation17:36 - Advancements in Egg Freezing Technology25:55 - Egg Freezing Recommendations26:34 - Collaboration Between Oncology and REI26:52 - Pediatric Oncology and Fertility Preservation28:58 - Ovarian Tissue Transplantation33:17 - Uterine Transposition Surgery40:05 - Gene Editing and Fertility Preservation43:01 - Financial and Emotional Aspects of Fertility Preservation48:02 - Practical Advice for OBGYNs51:12 - Resources and Final Thoughts --- RESOURCES Livestrong Fertilityhttps://livestrong.org/how-we-help/livestrong-fertility/ Resolve: The National Infertility Associationhttps://resolve.org/ Society for Assisted Reproductive Technologyhttps://www.sart.org/ American Society for Reproductive Medicinehttps://www.asrm.org/

In this episode of the Heal Your Hormones podcast, Dr. Danielle is joined by fertility preservation specialist, Dr. Knopman, ND to discuss the important topic of egg freezing, exploring its significance in women's health, fertility planning, and preventative care. They delve into the ideal timing for egg freezing, the emotional aspects of the process, and the myths surrounding fertility. The conversation also touches on the impact of the pandemic on fertility preservation, considerations for the LGBTQ community, and future technologies in the field. Dr. Knopman emphasizes the importance of knowledge and data in empowering women to make informed decisions about their reproductive health.About Dr. Knopman, MD:Dr. Jaime M. Knopman is a board-certified reproductive endocrinologist with years of experience in PCOS, IUI, and IVS treatment as well as gestational surrogacy. She serves as the Director of Fertility Preservation for CCRM Fertility of New York and is the author of Own Your Fertility. To learn more about Dr. Knopman or buy her book, click the links below.InstagramConnect with her at CCRMOwn Your Fertility on Amazon Let's ConnectInterested in becoming a client? ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Schedule your strategy call here.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Join the newsletter here!⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Order Your Own Labs - LabShop⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Fullscript Supplement Dispensary⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

Perimenopause isn't just hot flashes and mood shifts — for many women, it can be a silent fertility disruptor. In today's episode of Living Life Naturally, Lynne Wadsworth sits down with Dr. Jaime Knopman, double board-certified reproductive endocrinologist and fertility expert, to talk about what's really happening with egg quality, ovulation, IVF outcomes, and why so many women feel dismissed or misdiagnosed in midlife. We also explore practical ways to advocate for better care — from tracking cycles and symptoms, to bringing a "plus one" to appointments, to understanding why hormones can be tricky to measure in a single blood draw. And if someone you love is navigating infertility, Dr. Knopman shares one of the most powerful reminders: presence matters more than perfect words. You'll learn: How perimenopause impacts fertility and IVF success Why cycles become irregular and timing gets harder What egg freezing can do (and when it's most effective) Why symptom + cycle tracking can be more helpful than "one lab test" How to advocate for yourself at the doctor — and what to bring to appointment How to support a loved one going through infertility (without saying the wrong thing) Guest: Dr. Jaime Knopman — Medical Director of Chick Mission; former Director of Fertility Preservation at CCRM NY; Castle Connolly Top Doctor; author of Own Your Fertility. In this episode, we cover: Perimenopause & fertility Why egg quantity and quality decline in perimenopause How irregular ovulation can make conception harder What it means for IVF outcomes and pregnancy viability Egg freezing & planning ahead Why freezing eggs earlier can change options later "Serving as your own egg donor" — what that really means Why women get missed or dismissed Menopause "having its moment" — and why that matters Why infertility deserves to be part of the menopause conversation too How to support someone in infertility The power of simply showing up What to say when you're afraid of saying the wrong thing Being present in someone else's discomfort Hormone testing + advocating for care Why hormones aren't a simple snapshot The value of tracking cycles + symptoms   Why progesterone can swing dramatically Questions to bring to your appointment + why a "plus one" helps HRT, bioidenticals & pellets Why symptom relief often matters more than chasing a number Different options work for different bodies (no one-size-fits-all) Mentioned in this episode: ·         Book: Own Your Fertility: From Egg Freezing to Surrogacy — How to Take Charge of Your Body and Your Future (also available at Amazon or Barnes & Noble) Connect with Dr. Jaime Knopman Website: https://drjaimeknopman.com/ Connect with Lynne Join the Facebook community: Energized Healthy Women's Club         Website:  https://holistic-healthandwellness.com Facebook: https://www.facebook.com/holistichealthandwellnessllc Instagram: https://www.instagram.com/lynnewadsworth LinkedIn:  https://www.linkedin.com/in/lynnewadsworth   

This week on Motherhood Intended, Jacqueline closes out Season 6 with a meaningful re-air of one of the earliest and most impactful episodes from Season 1: “Egg Preservation: A Story of 10 Maybe Babies.”This episode intentionally follows last week's solo conversation about freezing your eggs and fertility timelines — and serves as a bridge into what's coming next.In this episode, Jacqueline chats with Alison, who shares her personal experience choosing to freeze her eggs. Alison walks through what the egg freezing process actually looked like, what she felt emotionally along the way, and what it meant to preserve her fertility and create options for her future — not guarantees, but possibilities.This re-air also marks the end of a season that looked different. Jacqueline reflects on balancing motherhood, work, and growth; learning new systems; building Your Fertility Village; and embracing the idea that there is power in the pause.And this story doesn't end here.When Season 7 begins, Alison will return to share where her egg-freezing journey from three years ago ultimately led her — offering listeners a rare, full-circle update.Whether you're considering egg freezing, supporting someone who is, or simply trying to understand your fertility options, this episode offers an honest, real-life perspective that continues to resonate.What's Coming Up• Season 7 premieres on January 8, 2026• Your Fertility Village officially launches in the new year • Founding members can join now for $7/month, locked in for life • An in-person gathering is coming in January — follow along to stay updated!Support the show__________________________________________________________________________________

Family planning and fertility preservation can pose challenges for trainees and new surgical oncology attendings. The SSO Fellows and Young Attendings Committee tackles these topics within a three-part podcast. On this episode of SurgOnc Today, hosts Dr. Danielle Graham and Dr. Paige Aiello discuss fertility preservation techniques and other considerations with reproductive endocrinologist Dr. Nicole Budrys and surgeons Dr. Alisa Blumenthaler and Dr. Jordan Jackson.

As we head into 2026, more women than ever are asking themselves a deeply personal and surprisingly common question: “Should I freeze my eggs?” In today's solo episode, Jacqueline breaks down everything you need to know about egg freezing right now — including age-related success rates, how many eggs you actually need, what the process looks like, and what the emotional side of delayed motherhood really feels like.Whether you're considering freezing your eggs for peace of mind, navigating an uncertain timeline, or simply curious about what egg freezing in 2026 can offer, this episode is your warm, big-sister style guide to understanding your options.Jacqueline also shares why this topic matters now more than ever and sets up an upcoming two-part story you won't want to miss. Next week, she's re-airing a powerful conversation with a woman who froze her eggs a few years ago — and in early January, you'll hear her updated journey through donor sperm, IVF, and the arrival of her miracle baby boy.If fertility, family planning, or delaying motherhood is on your mind, this episode will give you clarity, compassion, and truly helpful information as you head into the new year.IN THIS EPISODE, WE COVER:Why egg freezing is trending as we enter 2026The biggest question: “Should I freeze my eggs?”How age impacts egg quality, quantity, and success ratesWhat egg freezing success looks like in 2026 (by age group)How many eggs you actually need for a future pregnancyWhat the egg freezing process involves — step-by-stepThe real costs women should expect in 2026Common myths about egg freezing (and what's actually true)The emotional side of delayed motherhoodHow this episode connects to next week's re-air and the Season 7 premiereJoin Your Fertility Village — A supportive membership community for women navigating infertility, fertility preservation, and motherhood → https://your-fertility-village.mn.co/landing  Follow along on Instagram → @motherhood_intendedConnect with other listeners → Motherhood Intended Podcast CommunitySupport the show__________________________________________________________________________________

Today's episode is one of the most eye-opening fertility conversations we've ever had — and honestly, it's the one we wish every woman could hear in her 20s. This is not fear-based, not medical-jargon-heavy, and not judgmental. It's a raw, honest, compassionate conversation about fertility preservation, egg freezing, AMH, ovarian reserve, and the real options women have — if they get the information early enough.We talk openly about what's happening biologically, socially, and clinically, and why so many women are blindsided by fertility challenges in their 30s… even the healthiest ones.You'll hear real patient stories (anonymized), real numbers, real frustrations, and real hope.Get ready for an incredible episode!

A New Podcast from Obstetrics & Gynecology, featuring members from the Editorial Team and contributing authors, each month as they highlight the latest research and practice updates in the field. This episode features an interview with Dr. Shant Apelian, author of “Uterine Transposition for Fertility Preservation and Ovarian Conservation in Patients Undergoing Pelvic Radiotherapy.”

Send us a textFreezing is one of the most powerful tools in modern fertility—but it's also one of the most misunderstood. In this episode of Taco Bout Fertility Tuesday, Dr. Mark Amols unpacks the science behind freezing sperm, eggs, and embryos. Why do eggs and embryos need vitrification while sperm are slow-frozen? Does freezing harm fertility? Why can't multiple sperm samples just be frozen and combined for IUI? And does the length of time embryos are frozen affect success?From the history of freezing to survival rates and real-life applications, this episode answers your biggest questions and clears up the myths.Thanks for tuning in to another episode of 'Taco Bout Fertility Tuesday' with Dr. Mark Amols. If you found this episode insightful, please share it with friends and family who might benefit from our discussion. Remember, your feedback is invaluable to us – leave us a review on Apple Podcasts, Spotify, or your preferred listening platform. Stay connected with us for updates and fertility tips – follow us on Facebook. For more resources and information, visit our website at www.NewDirectionFertility.com. Have a question or a topic you'd like us to cover? We'd love to hear from you! Reach out to us at TBFT@NewDirectionFertility.com. Join us next Tuesday for more discussions on fertility, where we blend medical expertise with a touch of humor to make complex topics accessible and engaging. Until then, keep the conversation going and remember: understanding your fertility is a journey we're on together.

In this episode, I sit down with Dr. Taraneh Nazem, a board-certified reproductive endocrinologist and infertility specialist at RMA of New York, to demystify the process of egg freezing and other fertility treatments. We unpack the science, the myths, and the realities behind egg and embryo freezing, IVF, recovery, risks, and financial considerations. Dr. Nazem's warm, compassionate approach shines through as she provides clarity, reassurance, and practical advice for anyone thinking about fertility preservation.Whether you're curious about egg freezing, actively planning, or just want to understand your options, this conversation will leave you more informed and empowered to make decisions about your reproductive future.In this episode, you'll hear:The differences between egg freezing, embryo freezing, and IVF — and how they fit together.What actually happens during a typical two-week egg freezing cycle, from hormone injections to retrieval and recovery.Common side effects, rare complications, and what to expect after the procedure.Costs, insurance coverage, and financing options to explore.Answering all your FAQs, and more!Follow Dr. NazemGet in touch with Dr. NazemFollow @mannatplease on TikTok and Instagram for more exclusive content and insights. Don't miss out

Guest: Teonna Woolford, CEO & Co-Founder, SC RED Host: Dan Bulger, Progyny      Teonna had always known she wanted to have a lot of kids. At the age of nineteen, she discovered something that would change the trajectory of her life: she might be infertile due to sickle cell disease.   Despite years of managing sickle cell, in and out of hospitals, doctor's offices, and attending sickle cell conventions, no one had ever talked to her about the link between sickle cell and infertility. Unfortunately, fertility preservation was too financially out of reach.  But Teonna's story didn't stop there. She endured a failed bone marrow transplant, chronic pain, and the emotional toll of navigating a healthcare system that often overlooks the reproductive needs of those living with this chronic illness. Out of that struggle came a new purpose. Teonna co-founded SC RED (Sickle Cell Reproductive Health Education Directive) to raise awareness, expand education, and fight for equitable access to fertility care for those with sickle cell disease.  In this episode, Teonna opens up about her journey and why she's determined to ensure no one else faces the same barriers alone. This Sickle Cell Awareness Month, she hopes that the future of living with sickle cell can be about thriving and not just surviving.   For more information, visit Progyny's Podcast page and Progyny's Education page for more resources. Be sure to follow us on Instagram, @ThisisInfertilityPodcast and use the #ThisisInfertility. Have a question, comment, or want to share your story? Email us at thisisinfertility@progyny.com.    Watch this episode on YouTube:  https://youtu.be/tJXUXwChtA8 

In this episode, Dr. Uchenna Kennedy (CH) talks about the growing importance of fertility preservation in pediatric patients, particularly those undergoing cancer treatment.Dr. Kennedy explains the reasons behind adding fertility preservation to clinical guidelines, and the increasing survival rates of children with cancer. She also explores the effects of chemotherapy on the ovarian reserve in girls and the role of a pediatric multidisciplinary team in managing fertility preservation.The episode covers various fertility preservation options, including ovarian tissue retrieval, oocyte retrieval, and ovarian transposition, as well as the outcomes and challenges associated with these procedures.Shifting to boys, Dr. Kennedy addresses cryopreservation techniques, including sperm cryopreservation for postpbertal boys and the experimental status of testicular tissue cryopreservation for prepubertal boys.Finally, she outlines the current state of these procedures and the ongoing advancements in the field.For more EAU podcasts, please go to your favourite podcast app and subscribe to our podcast channel for regular updates: Apple Podcasts, Spotify, EAU YouTube channel.

“She's triple negative and has a very, very aggressive tumor. Instead of going on spring break that year, she sat in our chemo room and got chemo. Her friends from college are good to try to keep her involved and try to surround her and encourage her, but they're right now in very, very different spots in their lives. She's fighting for her life; her friends are fighting for the grade they get in a class—and that's different,” ONS member Kristi Orbaugh, MSN, NP, AOCN®, AOCNP®, nurse practitioner at Community Hospital North Cancer Center in Indianapolis, IN, told Jaime Weimer, MSN, RN, AGCNS-BS, AOCNS®, manager of oncology nursing practice at ONS, during a conversation about metastatic breast cancer in adolescent and young adult patients. Music Credit: “Fireflies and Stardust” by Kevin MacLeod Licensed under Creative Commons by Attribution 3.0  This podcast is sponsored by Lilly and is not eligible for NCPD contact hours. ONS is solely responsible for the criteria, objectives, content, quality, and scientific integrity of its programs and publications. Episode Notes This episode is not eligible for NCPD. ONS Podcast™ episodes: Episode 368: Best Practices for Challenging Patient Conversations in Metastatic Breast Cancer Episode 354: Breast Cancer Survivorship Considerations for Nurses Episode 350: Breast Cancer Treatment Considerations for Nurses Episode 345: Breast Cancer Screening, Detection, and Disparities Episode 307: AYAs With Cancer: Financial Toxicity Episode 300: AYAs With Cancer: End-of-Life Care Planning ONS Voice articles: ‘Cancer Ghosting' May Add Another Layer of Emotional Burden for Patients Discoveries in Race-Related Breast Cancer Biomarkers May Improve Precision Treatments What Is HER-2-Low Breast Cancer? What Oncology Nurses Need to Know About Supporting AYAs With Cancer ONS books: Guide to Breast Cancer for Oncology Nurses Oncology Nursing Forum articles: An Integrative Review of the Role of Nurses in Fertility Preservation for Adolescents and Young Adults With Cancer Impact of Race and Area Deprivation on Triple-Negative Metastatic Breast Cancer Outcomes Relations of Mindfulness and Illness Acceptance With Psychosocial Functioning in Patients With Metastatic Breast Cancer and Caregivers ONS huddle cards: Altered Body Image Fertility Preservation Sexuality Other ONS resources: Breast Cancer Learning Library Fertility Preservation in Individuals With Cancer ONS Biomarker Database American Cancer Society's breast cancer resources American Society of Clinical Oncology continuing education resources Elephants and Tea Life, Interrupted Livestrong National Cancer Institute's breast cancer resources Stupid Cancer Young Survival Coalition To discuss the information in this episode with other oncology nurses, visit the ONS Communities.  To find resources for creating an ONS Podcast club in your chapter or nursing community, visit the ONS Podcast Library. To provide feedback or otherwise reach ONS about the podcast, email pubONSVoice@ons.org. Highlights From This Episode “When we use ‘adolescent and young adult,' we're really talking about age 19–35. Some groups will say 15–39, but right around that age. When we think about that age, think about what all could be going on during those ages. Late teenagers, they may be going off to college, they may be graduating high school, trying to set up their own life, trying to become independent from mom and dad. If you're talking about early to mid 30s, you could be talking about young parents, young career folks. So, just setting that into place makes you realize this can be a very tumultuous time for folks.” TS 2:06 “Unfortunately, this group tends to have more aggressive subtypes. We see more triple-negative in this group. We see more hormone-negative, HER2-positive in this group. Normal breast cancer cells should be stimulated by hormone. They are stimulated by hormones. So when you have a breast cancer cell that is not driven by hormones, it's much more difficult to treat. We tend to see more aggressiveness in these tumors. We also see a higher incidence in non-Caucasian folks in this age group compared to the older age groups.” TS 4:53 “I think we have gotten much better about understanding the importance of fertility preservation and getting reproductive endocrinologists in, sooner rather than later. If we have earlier-stage cancers and we have patients that want to try to preserve eggs, preserve fertility, sperm banking. … If you have that time to talk to them—maybe a 21-year-old—the primary thing on her mind is not how many children she wants to have one day. Maybe she's not even thought about having kids yet. It's still a question you need to [ask]. Do you want to try to preserve fertility? Do you want to try to harvest some eggs? That's a conversation that needs to be had and is very, very important for that age group.” TS 10:35 “One thing that helps is if you can get them [into] reputable support groups with people their own age that are going through what they're going through. Someone else that doesn't have hair, someone else that isn't going to make it to the big board meeting or isn't going to get the promotion this year because they've had to take a medical leave. Someone else that understands it differently.” TS 16:47 “In breast cancer, many of those biomarkers just get reflexed. And what I mean by reflexed is a breast cancer pathology comes through, or a breast cancer specimen comes through, and it just automatically gets tested for X, Y, Z. HER2 and of course ER/PR. Now we understand that we don't just need to know whether they're HER2 positive or HER2 negative. We need to know: What is the IHC score? And even if the IHC score is zero, is there any membrane staining? And then we need to know what's their ESR1, their PTEN, their AKT, their PIK3CA. Those are so important to know.” TS 18:11 “I think it's important to try to remember what our priorities were when we were in our 20s—what our priorities were when we were starting out as young mothers or starting out our career. Because that's where these folks are. … I can't imagine in the midst of college, when I'm trying to be independent, to suddenly have to be at home and rely on my mom to take me to my chemo appointment. … So I think one really important bias is to remember where they are in the developmental stages of life. They're not 40-something. They haven't lived X amount of life, and we need to take a step back and try to remember when we were their age, what was important to us? Where were our priorities at that point? And then hear them when they're telling us what's important to them.” TS 29:22 “From a female standpoint … we frequently throw these patients into menopause or have early menopausal symptoms, and I think we forget how devastating that can be. … They now are at higher risk for osteopenia or osteoporosis. … And then we tell people, ‘Be as normal as possible, get back and do those normal things.' Well, they're in a relationship, and they want to be intimate [but] suddenly having sexual intercourse is incredibly painful. Or if it's not painful, sometimes they've just lost pure interest in that. They don't feel confident about their body. All of those things need to be addressed because patients are trying to live each day as normally as possible.” TS 31:55 

The incidence of early onset colorectal cancer (EOCRC) has been rising prompting the change in change in screening guidelines to 45 years of age for average risk patients. Join us for an in-depth discussion with guest speakers Dr. Andrea Cercek and Dr. Nancy You, where we provide a comprehensive look at the growing challenge of EOCRC. Hosts: - Dr. Janet Alvarez - General Surgery Resident at New York Medical College/Metropolitan Hospital Center - Dr. Wini Zambare – General Surgery Resident at Weill Cornell Medical Center/New York Presbyterian - Dr. Phil Bauer, Graduating Colorectal Surgical Oncology Fellow at Memorial Sloan Kettering Cancer Center  - Dr. J. Joshua Smith MD, PhD, Chair, Department of Colon and Rectal Surgery at MD Anderson Cancer Center - Dr. Andrea Cercek - Gastrointestinal Medical Oncologist at Memorial Sloan Kettering Cancer Center - Dr. Y. Nancy You, MD MHSc - Professor, Department of Colon and Rectal Surgery at MD Anderson Cancer Center Learning objectives:  - Describe trends in incidence of colorectal cancer, with emphasis on the rise of EOCRC. - Identify age groups and demographics most affected by EOCRC. - Summarize USPSTF recommendations for colorectal cancer screening. - Distinguish between screening methods (e.g., colonoscopy, FIT-DNA) and their sensitivity. - Understand treatment approaches for colon and rectal cancer (CRC) - Understand the role of mismatch repair (MMR) status in guiding treatment. - Outline the importance of genetic counseling and testing in young patients. - Discuss racial, ethnic, and socioeconomic disparities in CRC incidence and outcomes. - Describe the impact of cancer treatment on fertility and sexual health. -  Review fertility preservation options. - Identify the value of integrated care teams for young CRC patients. References: 1.         Siegel, R. L. et al. Colorectal Cancer Incidence Patterns in the United States, 1974–2013. JNCI J. Natl. Cancer Inst. 109, djw322 (2017). https://pubmed.ncbi.nlm.nih.gov/28376186/ 2.         Abboud, Y. et al. Rising Incidence and Mortality of Early-Onset Colorectal Cancer in Young Cohorts Associated with Delayed Diagnosis. Cancers 17, 1500 (2025). https://pubmed.ncbi.nlm.nih.gov/40361427/ 3.         Phang, R. et al. Is the Incidence of Early-Onset Adenocarcinomas in Aotearoa New Zealand Increasing? Asia Pac. J. Clin. Oncol.https://pubmed.ncbi.nlm.nih.gov/40384533/ 4.         Vitaloni, M. et al. Clinical challenges and patient experiences in early-onset colorectal cancer: insights from seven European countries. BMC Gastroenterol. 25, 378 (2025). https://pubmed.ncbi.nlm.nih.gov/40375142/ 5.         Siegel, R. L. et al. Global patterns and trends in colorectal cancer incidence in young adults. (2019) doi:10.1136/gutjnl-2019-319511. https://pubmed.ncbi.nlm.nih.gov/31488504/ 6.         Cercek, A. et al. A Comprehensive Comparison of Early-Onset and Average-Onset Colorectal Cancers. J. Natl. Cancer Inst. 113, 1683–1692 (2021). https://pubmed.ncbi.nlm.nih.gov/34405229/ 7.         Zheng, X. et al. Comprehensive Assessment of Diet Quality and Risk of Precursors of Early-Onset Colorectal Cancer. JNCI J. Natl. Cancer Inst. 113, 543–552 (2021). https://pubmed.ncbi.nlm.nih.gov/33136160/ 8.         Standl, E. & Schnell, O. Increased Risk of Cancer—An Integral Component of the Cardio–Renal–Metabolic Disease Cluster and Its Management. Cells 14, 564 (2025). https://pubmed.ncbi.nlm.nih.gov/40277890/ 9.         Muller, C., Ihionkhan, E., Stoffel, E. M. & Kupfer, S. S. Disparities in Early-Onset Colorectal Cancer. Cells 10, 1018 (2021). https://pubmed.ncbi.nlm.nih.gov/33925893/ 10.       US Preventive Services Task Force. Screening for Colorectal Cancer: US Preventive Services Task Force Recommendation Statement. JAMA 325, 1965–1977 (2021). https://pubmed.ncbi.nlm.nih.gov/34003218/ 11.       Fwelo, P. et al. Differential Colorectal Cancer Mortality Across Racial and Ethnic Groups: Impact of Socioeconomic Status, Clinicopathology, and Treatment-Related Factors. Cancer Med. 14, e70612 (2025). https://pubmed.ncbi.nlm.nih.gov/40040375/ 12.       Lansdorp-Vogelaar, I. et al. Contribution of Screening and Survival Differences to Racial Disparities in Colorectal Cancer Rates. Cancer Epidemiol. Biomarkers Prev. 21, 728–736 (2012). https://pubmed.ncbi.nlm.nih.gov/22514249/ 13.       Ko, T. M. et al. Low neighborhood socioeconomic status is associated with poor outcomes in young adults with colorectal cancer. Surgery 176, 626–632 (2024). https://pubmed.ncbi.nlm.nih.gov/38972769/ 14.       Siegel, R. L., Wagle, N. S., Cercek, A., Smith, R. A. & Jemal, A. Colorectal cancer statistics, 2023. CA. Cancer J. Clin. 73, 233–254 (2023). https://pubmed.ncbi.nlm.nih.gov/36856579/ 15.       Jain, S., Maque, J., Galoosian, A., Osuna-Garcia, A. & May, F. P. Optimal Strategies for Colorectal Cancer Screening. Curr. Treat. Options Oncol. 23, 474–493 (2022). https://pubmed.ncbi.nlm.nih.gov/35316477/ 16.       Zauber, A. G. The Impact of Screening on Colorectal Cancer Mortality and Incidence: Has It Really Made a Difference? Dig. Dis. Sci. 60, 681–691 (2015). https://pubmed.ncbi.nlm.nih.gov/25740556/ 17.       Edwards, B. K. et al. Annual report to the nation on the status of cancer, 1975-2006, featuring colorectal cancer trends and impact of interventions (risk factors, screening, and treatment) to reduce future rates. Cancer 116, 544–573 (2010). https://pubmed.ncbi.nlm.nih.gov/19998273/ 18.       Cercek, A. et al. Nonoperative Management of Mismatch Repair–Deficient Tumors. New England Journal of Medicine 392, 2297–2308 (2025). https://pubmed.ncbi.nlm.nih.gov/40293177/ 19.       Monge, C., Waldrup, B., Carranza, F. G. & Velazquez-Villarreal, E. Molecular Heterogeneity in Early-Onset Colorectal Cancer: Pathway-Specific Insights in High-Risk Populations. Cancers 17, 1325 (2025). https://pubmed.ncbi.nlm.nih.gov/40282501/ 20.       Monge, C., Waldrup, B., Carranza, F. G. & Velazquez-Villarreal, E. Ethnicity-Specific Molecular Alterations in MAPK and JAK/STAT Pathways in Early-Onset Colorectal Cancer. Cancers 17, 1093 (2025). https://pubmed.ncbi.nlm.nih.gov/40227607/ 21.       Benson, A. B. et al. Colon Cancer, Version 2.2021, NCCN Clinical Practice Guidelines in Oncology. J. Natl. Compr. Cancer Netw. JNCCN 19, 329–359 (2021). https://pubmed.ncbi.nlm.nih.gov/33724754/ 22.       Christenson, E. S. et al. Nivolumab and Relatlimab for the treatment of patients with unresectable or metastatic mismatch repair proficient colorectal cancer. https://pubmed.ncbi.nlm.nih.gov/40388545/ 23.       Dasari, A. et al. Fruquintinib versus placebo in patients with refractory metastatic colorectal cancer (FRESCO-2): an international, multicentre, randomised, double-blind, phase 3 study. The Lancet 402, 41–53 (2023). https://pubmed.ncbi.nlm.nih.gov/37331369/ 24.       Strickler, J. H. et al. Tucatinib plus trastuzumab for chemotherapy-refractory, HER2-positive, RAS wild-type unresectable or metastatic colorectal cancer (MOUNTAINEER): a multicentre, open-label, phase 2 study. Lancet Oncol. 24, 496–508 (2023). https://pubmed.ncbi.nlm.nih.gov/37142372/ 25.       Sauer, R. et al. Preoperative versus Postoperative Chemoradiotherapy for Rectal Cancer. N. Engl. J. Med. 351, 1731–1740 (2004). https://pubmed.ncbi.nlm.nih.gov/15496622/ 26.       Cercek, A. et al. Adoption of Total Neoadjuvant Therapy for Locally Advanced Rectal Cancer. JAMA Oncol. 4, e180071 (2018). https://pubmed.ncbi.nlm.nih.gov/29566109/ 27.       Garcia-Aguilar, J. et al. Organ Preservation in Patients With Rectal Adenocarcinoma Treated With Total Neoadjuvant Therapy. J. Clin. Oncol. 40, 2546–2556 (2022). https://pubmed.ncbi.nlm.nih.gov/35483010/ 28.       Schrag, D. et al. Preoperative Treatment of Locally Advanced Rectal Cancer. N. Engl. J. Med. 389, 322–334 (2023). https://pubmed.ncbi.nlm.nih.gov/37272534/ 29.       Kunkler, I. H., Williams, L. J., Jack, W. J. L., Cameron, D. A. & Dixon, J. M. Breast-Conserving Surgery with or without Irradiation in Early Breast Cancer. N. Engl. J. Med. 388, 585–594 (2023). https://pubmed.ncbi.nlm.nih.gov/36791159/ 30.       Jacobsen, R. L., Macpherson, C. F., Pflugeisen, B. M. & Johnson, R. H. Care Experience, by Site of Care, for Adolescents and Young Adults With Cancer. JCO Oncol. Pract. (2021) doi:10.1200/OP.20.00840. https://pubmed.ncbi.nlm.nih.gov/33566700/ 31.       Ruddy, K. J. et al. Prospective Study of Fertility Concerns and Preservation Strategies in Young Women With Breast Cancer. J. Clin. Oncol. (2014) doi:10.1200/JCO.2013.52.8877. https://pubmed.ncbi.nlm.nih.gov/24567428/ 32.       Su, H. I. et al. Fertility Preservation in People With Cancer: ASCO Guideline Update. J. Clin. Oncol. 43, 1488–1515 (2025). https://pubmed.ncbi.nlm.nih.gov/40106739/ 33.       Smith, K. L., Gracia, C., Sokalska, A. & Moore, H. Advances in Fertility Preservation for Young Women With Cancer. Am. Soc. Clin. Oncol. Educ. Book 27–37 (2018) doi:10.1200/EDBK_208301. https://pubmed.ncbi.nlm.nih.gov/30231357/ 34.       Blumenfeld, Z. How to Preserve Fertility in Young Women Exposed to Chemotherapy? The Role of GnRH Agonist Cotreatment in Addition to Cryopreservation of Embrya, Oocytes, or Ovaries. The Oncologist 12, 1044–1054 (2007). 35.       Bhagavath, B. The current and future state of surgery in reproductive endocrinology. Curr. Opin. Obstet. Gynecol. 34, 164 (2022). 36.       Ribeiro, R. et al. Uterine transposition: technique and a case report. Fertil. Steril. 108, 320-324.e1 (2017). 37.       Yazdani, A., Sweterlitsch, K. M., Kim, H., Flyckt, R. L. & Christianson, M. S. Surgical Innovations to Protect Fertility from Oncologic Pelvic Radiation Therapy: Ovarian Transposition and Uterine Fixation. J. Clin. Med. 13, 5577 (2024). 38.       Holowatyj, A. N., Eng, C. & Lewis, M. A. Incorporating Reproductive Health in the Clinical Management of Early-Onset Colorectal Cancer. JCO Oncol. Pract. 18, 169–172 (2022). ***Behind the Knife Colorectal Surgery Oral Board Audio Review: https://app.behindtheknife.org/course-details/colorectal-surgery-oral-board-audio-review Please visit https://behindtheknife.org to access other high-yield surgical education podcasts, videos and more.   If you liked this episode, check out our recent episodes here: https://app.behindtheknife.org/listen

Antoni J. Duleba, M.D. outlines the broad scope of reproductive endocrinology and infertility, emphasizing care across a woman's lifespan—from adolescence through menopause. He explains common endocrine conditions like polycystic ovary syndrome (PCOS), endometriosis, and menstrual disorders, all of which can affect fertility and overall health. Duleba highlights advances in fertility preservation, especially for patients undergoing cancer treatment, and notes the rising need for such services as more women delay childbearing. He also addresses efforts to improve hormonal therapies, IVF outcomes, and treatments that target inflammation and the microbiome. In addition to medical innovation, he points to social and financial barriers that continue to limit access to reproductive care. Series: "Motherhood Channel" [Health and Medicine] [Show ID: 40672]

Antoni J. Duleba, M.D. outlines the broad scope of reproductive endocrinology and infertility, emphasizing care across a woman's lifespan—from adolescence through menopause. He explains common endocrine conditions like polycystic ovary syndrome (PCOS), endometriosis, and menstrual disorders, all of which can affect fertility and overall health. Duleba highlights advances in fertility preservation, especially for patients undergoing cancer treatment, and notes the rising need for such services as more women delay childbearing. He also addresses efforts to improve hormonal therapies, IVF outcomes, and treatments that target inflammation and the microbiome. In addition to medical innovation, he points to social and financial barriers that continue to limit access to reproductive care. Series: "Motherhood Channel" [Health and Medicine] [Show ID: 40672]

Antoni J. Duleba, M.D. outlines the broad scope of reproductive endocrinology and infertility, emphasizing care across a woman's lifespan—from adolescence through menopause. He explains common endocrine conditions like polycystic ovary syndrome (PCOS), endometriosis, and menstrual disorders, all of which can affect fertility and overall health. Duleba highlights advances in fertility preservation, especially for patients undergoing cancer treatment, and notes the rising need for such services as more women delay childbearing. He also addresses efforts to improve hormonal therapies, IVF outcomes, and treatments that target inflammation and the microbiome. In addition to medical innovation, he points to social and financial barriers that continue to limit access to reproductive care. Series: "Motherhood Channel" [Health and Medicine] [Show ID: 40672]

Today, Ali is talking to Dr. Nirali Jain, a Reproductive Endocrinologist at RMA, about the importance of fertility preservation for cancer patients. "I do feel like the system failed us a little bit, and I tell all my patients when they come in for their first visit, your entire life, you learned how to not get pregnant, and you never thought you'd be sitting in this office learning about timed intercourse and figuring out when you're ovulating," Dr. Jain says. Ali and Dr. Jain talk about how chemo can affect fertility, what your options are when you get a cancer diagnosis, and how to get a referral to a fertility specialist from your oncologist. If you or anyone you know has recently been diagnosed with cancer and you're interested in preserving your fertility, this is a must listen! Spread the word!  Follow Dr. Jain on IG: @eggspert_mdTOPICS COVERED IN THIS EPISODE: Cancer; chemotherapy; chemo agents; egg quality; egg freezing; embryo freezing; advocacy; trying to conceive; timed intercourse; ovulation EPISODE SPONSORS: BEAUTIFUL BIRD AND WORK OF ARTAli's Children's Book Series about IVF, IUI and Family Building Through Assisted Reproductive Technology https://www.infertileafgroup.com/booksThe latest book in the Work of ART series, “Beautiful Bird” tells the story of three parents, one incredible boy and a family built with love—and a little bit of science.Pre-orders are available now! The first 150 copies will be Personalized, Signed and Numbered! Don't miss out on this limited edition! Tap the link in bio and stories to order your copy today.When Helen decides to have a baby on her own, she welcomes Jack Bird into the world through IUI with the help of her friend, Aaron. But when Jack is born and needs extra care in the NICU, Aaron and his partner, Blake, fall in love with Jack, too. Together, the three join forces to raise Jack, proving that family isn't about how you start—it's about how you grow.Order yours now at https://www.infertileafgroup.com/booksFor bulk orders of 10 or more books at 20% off, go to https://www.infertileafgroup.com/bulk-order-requestFERTILITY RALLYIG: @fertilityrallywww.fertilityrally.comNo one should go through infertility alone. Join the Worst Club with the Best Members at fertilityrally.com. We offer 5 to 6 support groups per week, three private Facebook groups, tons of curated IRL and virtual events, and an entire community of more than 500 women available to support you, no matter where you are in your journey.Join today at link in bio on IG @fertilityrally or at www.fertilityrally.com/membershipGENERATIONS CRYOVAULTwww.gencryo.comIG: @generationscryovaultWhen you're navigating fertility treatments, every decision feels big—because it is big. But did you know that when it comes to storing your reproductive tissue—including eggs, sperm, and embryos—you DO have a choice? Most clinics automatically store your tissues—or hand you off to their partner. But guess what? It doesn't have to be that way. Enter Generations CryoVault, which believes in the motto, "Your tissues. Your choice." When you choose to work with Generations CryoVault, they help you transfer your tissues securely and easily to their headquarters – a place you can trust. Take control of this part of your journey by visiting gencryo.com. And make sure to mention Infertile AF to receive 1 free month of storage.Advertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacySupport this podcast at https://redcircle.com/infertile-af/donationsOur Sponsors:* Check out Happy Mammoth and use my code INFERTILEAF for a great deal: https://happymammoth.comSupport this podcast at — https://redcircle.com/infertile-af/donationsAdvertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

In this episode, Dr. Carrie Bedient (Fertility Center of Las Vegas), Dr. Susan Hudson (Texas Fertility Center), and Dr. Abby Eblen (Nashville Fertility Center) welcome Lauren Makler, co-founder and CEO of Cofertility, for a powerful conversation about redefining egg donation and fertility preservation.Lauren shares how Cofertility is changing the landscape by giving young women, typically ages 21 to 34, the opportunity to freeze their eggs at the ideal time in life, at no cost, by donating half to intended parents. This fully disclosed, mutual-match model brings transparency and connection to a process that has long existed in the shadows.The group explores how Cofertility empowers intended parents to feel confident and proud in their family-building journey, and how donors find meaning in helping others conceive. The emotional and financial benefits are real—for both sides.Whether fresh or frozen eggs are used, this new approach is providing families with more options, greater openness, and increased hope. Tune in to hear how Cofertility is making egg donation a shared journey worth celebrating.

On this episode of The Wholesome Fertility Podcast, I am joined by Dr. Nirali Jain (eggspert_md), a board-certified OB/GYN and reproductive endocrinologist at Reproductive Medical Associates (RMA). Dr. Jain shares her expert insights on fertility preservation for individuals undergoing cancer treatment, a crucial yet often overlooked aspect of reproductive care. We explore what options are available for fertility preservation, including egg and sperm freezing, and why it's so important to initiate these discussions before starting chemotherapy or radiation. Dr. Jain also explains the difference between Letrozole and Clomid, the impact of estrogen-sensitive cancers on IVF treatments, and innovative approaches like random-start cycles and DuoStim protocols. Whether you're facing a cancer diagnosis or simply thinking proactively about your reproductive future, this conversation is filled with knowledge and reassurance. Key Takeaways: Why it's essential to discuss fertility before starting cancer treatment. The role of Letrozole in estrogen-sensitive cancers and fertility preservation. Differences between Letrozole and Clomid, and why Letrozole is often preferred. How new protocols like DuoStim and random-start cycles are improving outcomes. Why fertility preservation is important even for those without a cancer diagnosis. Guest Bio: Dr. Nirali Jain (@eggspert_md) is a board-certified OB/GYN and fertility specialist at Reproductive Medicine Associates (RMA) in Basking Ridge, New Jersey. She earned both her undergraduate degree in neurobiology (with a minor in dance!) and her medical degree from Northwestern University, before completing her residency at Weill Cornell/NYP, where she served as co-Chief Resident, and her fellowship in reproductive endocrinology and infertility at NYU Langone. Deeply passionate about women's health and fertility preservation, Dr. Jain blends the latest research and cutting-edge treatments with compassionate, patient-centered care. Her interests include third-party reproduction and oncofertility, and she is especially passionate about supporting patients navigating fertility preservation through a cancer diagnosis. Outside of the clinic, Dr. Jain is a trained dancer, a dedicated global traveler, and an adventurer working toward hiking all seven continents with her husband. Her diverse experiences, from international medical rotations to personal connections with friends and family navigating infertility, have shaped her into a warm, resourceful, and determined advocate for her patients. Links and Resources: Visit RMA websiteFollow Dr. Nirali Jain on Instagram For more information about Michelle, visit www.michelleoravitz.com To learn more about ancient wisdom and fertility, you can get Michelle's book at: https://www.michelleoravitz.com/thewayoffertility The Wholesome Fertility facebook group is where you can find free resources and support: https://www.facebook.com/groups/2149554308396504/ Instagram: @thewholesomelotusfertility Facebook: https://www.facebook.com/thewholesomelotus/ Disclaimer: The information shared on this podcast is for educational and informational purposes only and is not intended as medical advice. Please consult with your healthcare provider before making any changes to your health or fertility care. --  Transcript:   # TWF-Jain-Nirali (Video) ​[00:00:00]  **Michelle Oravitz:** Welcome to the podcast Jain.  **Dr. Nirali Jain:** Thanks so much for having me **Michelle Oravitz:** Yeah, so. **Michelle Oravitz:** I'm very excited to talk about this topic, which, um, actually you don't really hear a lot of people talking about, which is how to preserve your fertility if you're going through a cancer diagnosis and if you have to go through treatments. 'cause obviously that can impact a lot on fertility. **Michelle Oravitz:** I have, um, seen actually like a colleague of mine go through. And she also preserved her fertility and, and now she has a baby boy. so it's really nice. **Michelle Oravitz:** to **riverside_nirali_jain_raw-video-cfr_michelle_oravitz's _0181:** so nice. **Michelle Oravitz:** So I'd love for you first to introduce yourself and kind Of give us a background on how you got into this work. **Dr. Nirali Jain:** Of course. Um, so I am Dr. Narly Jane. I am, um, an OB GYN by training, and then I did an additional, after completing four years of residency in OB GYN and getting board certified in that, I did an additional training in reproductive endocrinology and [00:01:00] infertility or otherwise known as REI. So now I'm a fertility specialist. **Dr. Nirali Jain:** Um, I trained at Northwestern in Chicago, so I went to undergrad and medical school there. And then, um, home has always been New Jersey for me, so I moved back out east to New Jersey. Um, I did all my training actually in New York City at Cornell for residency and NYU for fellowship. Um, and then moved to the suburbs. **Dr. Nirali Jain:** Um, and now I'm a fertility specialist in, in Basking Ridge at Reproductive Medical Associates.  **Michelle Oravitz:** Very impressive background. That's awesome.  **Dr. Nirali Jain:** Yeah. **Michelle Oravitz:** I'd love to hear just really. About what your process is. If a person has been diagnosed with cancer, like what is the process? What are some of the things that you address if they are trying to preserve fertility, and what are some of the concerns going  **Dr. Nirali Jain:** yeah, yeah. All great questions. So, you know, there's a lot of us, uh, the Reis. Are a very small, [00:02:00] there's a very small number of us. So in terms of specializing in fertility preservation, technically we all are certified to treat patients with cancer and kind of move them through fertility preservation before starting chemotherapy. **Michelle Oravitz:** Mm-hmm.  **Dr. Nirali Jain:** Um, luckily we've been working closely with oncologists in the past several years just to establish some type of streamlined system because having a diagnosis of cancer and hearing all that information. Especially when you're young is so hard. So I think that's, that's where my interest started in terms of being able to speak to and counsel cancer patients. **Dr. Nirali Jain:** I think it is a very specific niche that you really have to be comfortable with in our field. Um, I. So I'll kind of walk you through, you know, what it, what does it look like, right? Um, you go into your oncologist's office suspecting that you have this, this lump. I'll take breast cancer, for example. It could really be any kind of cancer. **Dr. Nirali Jain:** Um, but breast cancer in a reproductive age patient or someone that's in those years where you're starting [00:03:00] to think about building a family, planning a family, um, or if you have kids at home, that's usually the type of patient that we see come in with a breast cancer diagnosis. So. Kinda just taking that, for example, um, the minute that you're diagnosed, it's really your oncologist's responsibility to counsel you on what treatment options are going to be offered to you. **Dr. Nirali Jain:** And then based off of the treatment options, it's important to know how that affects your reproduction. So how does it affect your ovaries in the short term, in the long term, um, in any way possible. So. Once a patient is initially referred from their oncologist to myself or any other fertility specialist, they come into my office and we just have a 30 minute conversation really talking about family planning goals. **Dr. Nirali Jain:** Any kids that they've had in the past either naturally conceived or through um, IVF, and then we talk about where they're at in their relationship. Are they married, are they not? Are they with a partner, [00:04:00] a male partner, a female partner, whatever it might be. It's important to know the social standpoint, um, especially in this sensitive phase of life. **Dr. Nirali Jain:** So patient patients usually spend anywhere from 30 minutes to an hour. Um, just kind of talking through where they're at, how they're feeling, what their ultimate childbearing goals are. And then from there we do an ultrasound and that's when I'm really able to see, you know, the, the reproductive status. **Dr. Nirali Jain:** So what do the ovaries look like? What does the uterus look like? Is there something that I need to be concerned about from a baseline GYN standpoint? Um, and all of those conversations are happening in real time. So. I think one of the things is patients come in and they're like, I'm already so overwhelmed with all this information from my oncologist, and now my fertility specialist is throwing all this information at me. **Dr. Nirali Jain:** Luckily, the way I like to frame it is you come in and you just let go. Like you let us do the work because in the background we're the ones talking to your oncologist. We're the [00:05:00] ones giving that feedback and creating a timeline with your oncologist. Um, and really I think just getting in the door is the hardest part. **Dr. Nirali Jain:** So once patients are here to see us, we go through the whole workup. We do anything that we would do for a normal patient that came in for fertility preservation. And then based off of where they're at in their journey, we talk about what makes sense for them, whether that means freezing embryos, freezing eggs, they're very similar in terms of the, the few weeks leading up to the egg retrievals. **Dr. Nirali Jain:** So I have that whole conversation just at the initial visit. And then from there we talk about the timeline behind the scenes and make sure that it works with their lives before moving forward. **Michelle Oravitz:** So for people listening to this, why, and this might be an obvious question, but to some it might not be,  **Dr. Nirali Jain:** Mm-hmm. **Michelle Oravitz:** why would somebody want to preserve. eggs or sperm. 'cause I've had actually some couples  **Dr. Nirali Jain:** Yep. **Michelle Oravitz:** come to me where the husband preserved the sperm and they had to go through IVF just because he was going [00:06:00] through cancer treatments. So he had to preserve the sperm ahead of time.  **Dr. Nirali Jain:** Mm-hmm. **Michelle Oravitz:** people need to consider doing that before doing cancer treatments?  **Dr. Nirali Jain:** So there are certain cancer treatments that do affect the ovaries and the sperm health, and you know, for men and women, it affects your reproductive organs. In a similar way, um, depending on the type of chemotherapeutic agent, there are some that are more dangerous in terms of, um, being toxic to your ovaries or toxic to your sperm. **Dr. Nirali Jain:** And those are the instances where we are really thinking about what's the long-term impact because there's medications that oncologists do give patients, and our oncologists are amazing, the ones that we work with, Memorial Sloan Kettering from Reproductive Medical Associates through RMA, um, and. **Dr. Nirali Jain:** They're just so good at what they do and are so well-trained, so they know in the back of their mind, is this going to impact your ovaries or your sperm health or not? Um, and I [00:07:00] think that any chemotherapy, you know, your ovaries are these, these small organs that are constantly turning over follicles every month. **Dr. Nirali Jain:** So every month we're losing those eggs, and if they don't become. If an egg isn't ovulated, it doesn't become a baby, it's just gonna die off. So I counsel even patients that don't have cancer, I counsel them on fertility preservation as young as possible. You know, between the ages of 28 and 35, that's like the best time to preserve your fertility. **Dr. Nirali Jain:** So in cancer patients, there's an extra level added to that where even if they are a little bit younger, a little bit older. Your eggs are not gonna be the same quality. There's gonna be higher level of chromosomal errors, more DNA breakage, um, and, and bigger issues that lead to issues with conceiving naturally afterwards. **Dr. Nirali Jain:** So I think that it's important to consider how that chemotherapy is going to affect them or how surgery would affect them if it was, for example, a GYN cancer where [00:08:00] we're removing a whole ovary, you know, what, what do we have to do to preserve your fertility in that case? And those are important conversations to have. **Michelle Oravitz:** Yeah. for sure. I know that a lot of people are also concerned, you know, with going through the IVF process, you're taking in a lot of estrogen, a lot of hormones, and many cancers are actually estrogen sensitive. So I wanted to talk to you about that. 'cause I know that the data shows that it's. It's been fine, which some people might find surprising, but I wanted you to address that and just kind of **Dr. Nirali Jain:** Yeah. **Michelle Oravitz:** from your perspective.  **Dr. Nirali Jain:** That's so interesting that you asked that question because I actually, my whole I I graduated fellowship last year and my entire, like passion project in fellowship was looking at one of the drugs that we use to suppress the estrogen levels specifically in cancer patients. Um, and I had presented this at a few of our reproductive meetings. **Dr. Nirali Jain:** Um, A SRM is one of our annual meetings where all of the reiss get together. A lot of male fertility [00:09:00] specialists come and we kinda just talk about. Specific things and fertility preservation for cancer patients is, has been an ongoing topic of interest for all of us. Um, and it's important to know that there are different medications that we can offer. **Dr. Nirali Jain:** Letrozole is the one that I, um, have a particular love for and I, uh, you know, I use all the time for my patients, um, for different reasons, but it suppresses the exposure that your body has to estrogen. And there's mixed data, um, out there in terms of, you know, does Letrozole suppression actually impact, you know, does it help or. **Dr. Nirali Jain:** Or does it have no impact on your future risk of cancer after treatment? Um, and that honestly is still up for debate. But what we do know is that there's no increased risk of cancer recurrence in patients that have undergone fertility preservation with or without Letrozole. Um, Letrozole is one of those things that we can give, and the way it works is basically. **Dr. Nirali Jain:** It masks that [00:10:00] conversion. It, it doesn't allow for conversion from those androgens in the male hormones over to estrogen. Um, and so your body doesn't really see that estrogen exposure. It stays nice and low throughout your cycle, and it does help with actually ovarian maturation and getting mature eggs harvested and, um, helps a little bit with, with quality too. **Dr. Nirali Jain:** So I think that it's really nice in terms of having that available to us, but know that. It's not, it's not essential that you have it, really, the data showing plus minus. Um, but there are certain things that we can do to protect the ovaries, protect your exposure to estrogen. Um, and so that shouldn't be top of mind of concern when we're going through fertility preservation, even with an estrogen sensitive cancer. **Michelle Oravitz:** Actually, so, uh, on a different topic, kind of going back to that, so Letrozole versus Clomid, I, it's like a, the questions I personally feel just based on what I've heard and like my own research that Letrozole would be kind of like the more. [00:11:00] Um, the, it's, it's a little better, but I know that it really depends on the person as well.  **Dr. Nirali Jain:** Yeah, **Michelle Oravitz:** they might do better with Clom, but I'd love to hear your perspective and kind of pick your brain on this.  **Dr. Nirali Jain:** totally. You're choosing all the, all the right questions because these are all of my, my specific interests and niches. So  **Michelle Oravitz:** Oh,  **Dr. Nirali Jain:** Letrozole is basically, you know, we use Letrozole and Clomid in. Patients that don't have cancer and patients that come in for an intrauterine insemination, that's kind of the most common scenario where we're thinking about, you know, which medication is better? **Dr. Nirali Jain:** Letrozole or Clomid and Clomid used to be the, the most common medication that we use, we dose patients, you know, have 50 milligrams of Clomid, give them five days of the medication. It's an oral pill. Feels really easy and. The way it works is really, it recruits more than one follicle, so it really helps with the release of, um, more than one follicle growing more than one follicle in the ovary. **Dr. Nirali Jain:** Um, but it has a little bit [00:12:00] higher of a risk of twins because that's exactly what it's good at. Um, Clomid, not so much in the cancer. In the cancer front, it's not really used there because it's considered, from a scientific perspective, it's considered like a selective estrogen receptor modulator. So it doesn't necessarily suppress your estrogen levels in the same way that Letrozole does versus. **Dr. Nirali Jain:** Letrozole is an aromatase inhibitor, so it really blocks the chemical conversion of one drug or one hormone to the other hormone. Um, the reason we love Letrozole so much, and I don't mean to like gush over Letrozole, but um, it's a mono follicular agent, so it works really well at recruiting one follicle  **Michelle Oravitz:** Mm-hmm.  **Dr. Nirali Jain:** you know, every OB-GYN's nightmare in a way is having multiples when you didn't intend on having multiples at all. **Michelle Oravitz:** so  **Dr. Nirali Jain:** Um. **Michelle Oravitz:** were saying that, um, there's more of a chance of twins, it's Clomid, not letrozole.  **Dr. Nirali Jain:** Yes, there's a higher chance with Clomid versus Letrozole. And I mean, don't get me wrong, there's a chance of twins with [00:13:00] any type of assisted reproductive technology. Even when we're doing single embryo transfers, there's a chance that it's gonna split. So, um, the chance is always there just like it is in the natural world. **Dr. Nirali Jain:** But we know for a fact that. CLO is really good at recruiting many follicles. It's good for certain patients that don't respond well to Letrozole. Um, but Letrozole is kind of our, our go-to drug these days just because of all the benefits that we've seen.  **Michelle Oravitz:** Awesome.  **Dr. Nirali Jain:** Yeah, **Michelle Oravitz:** These are all fun things to ask because I, I love talking to our eis 'cause there's so much information that I'm always  **Dr. Nirali Jain:** totally. **Michelle Oravitz:** learn a lot from my patients in my own research, but it's really cool. Picking your guys' brains. So another question I have, and I have actually talked to Dr. Andrea Elli, he's been on,  **Dr. Nirali Jain:** Mm-hmm. **Michelle Oravitz:** and he does a lot of endometriosis and, and immune related work as well,  **Dr. Nirali Jain:** Yeah. **Michelle Oravitz:** so. I'd love to know just from your perspective. One thing that I do know from, based on what I've heard is that the, [00:14:00] guess like you were just saying, that breast cancer or estrogen sensitive breast cancer doesn't seem to be affected by IVF cycles, however, and endometriosis lesions do get affected.  **Dr. Nirali Jain:** Yeah. **Dr. Nirali Jain:** that's a great question. So, you know, every, there are so many complex G mind diagnoses that the, that our patients come in with. Um, and endometriosis is a big one because there is clear data that endometriosis is linked to infertility. So we think about, you know, when a patient comes in with endometriosis, we really do think about the different treatment options and what are the short-term and long-term impacts of the hormones that we're giving 'em. **Dr. Nirali Jain:** Um, these days, again, kind of going back to Letrozole, we, letrozole is something that I give all of my endometriosis patients because it helps suppress their estrogen because we know.  **Michelle Oravitz:** interesting.  **Dr. Nirali Jain:** is very responsive to estrogen and leads to this dysfunctional regulation of all the endometrial tissue that can really flare in a, [00:15:00] in a cycle, or shortly after a cycle. **Dr. Nirali Jain:** I. So we really, for endometriosis patients, the, the best treatment is being on birth control because we don't see that hormonal fluctuation. The up and down of the estrogen and the progesterone, that's what leads to those flares. Um, so I really, I watch patients closely after their cycles too, because you definitely can have an endometriosis flare and we say the best treatment for endometriosis is pregnancy, right? **Dr. Nirali Jain:** That's when you're suppressed, that's when you're at your lowest. Um, and patients, my endo patients feel so good in pregnancy because they have. Hormones that are nice in that baseline, they're not getting periods of course. Um, and that's truly, truly the best treatment.  **Michelle Oravitz:** That's interesting.  **Dr. Nirali Jain:** But it is important to consider when you're going through infertility treatments. **Dr. Nirali Jain:** How does my endometriosis affect the short and long-term effects of the fertility medications? And really not to, not to say that they're bad in any way. I think a lot of endometriosis patients go through IVF and have success and do really, really well, and that's kind of the push that they need. [00:16:00] Um, but it's important to be mindful of the bigger picture here. **Dr. Nirali Jain:** It's not just, you're not just a number of. A patient with endo coming in, getting the same protocol. It's really individualized to the extent of your lesions, what symptoms you're having, what grade of endometriosis, where your lesions are. So we're the RAs are thinking about everything before we actually start your protocol. **Michelle Oravitz:** It's crazy how in depth it is, and it's, it, there's just so, it's so multifaceted,  **Dr. Nirali Jain:** Yeah,  **Michelle Oravitz:** when it's females  **Dr. Nirali Jain:** totally. **Michelle Oravitz:** are a little, I mean, they can, you know, there, there's definitely a number of things, but it's not as complicated and interconnected  **Dr. Nirali Jain:** Exactly. Exactly. That's so true. **Michelle Oravitz:** And so one question I actually have, this is kind of really off topic, but something that I was curious about. **Michelle Oravitz:** 'cause I heard about a while  **Dr. Nirali Jain:** Yeah. **Michelle Oravitz:** a, a type of cancer treatment that was used. I'm not sure exactly what it was, but for some reason it actually caused follicles to grow, [00:17:00] or to multiply. And they were **Dr. Nirali Jain:** Interesting. **Michelle Oravitz:** this definitely. Puts, um, the whole idea of like a woman being born with all the follicles she'll ever have on its head, I thought that was really Interesting. **Michelle Oravitz:** Now I learned a little bit about it. I don't think it really went further than that,  **Dr. Nirali Jain:** Mm-hmm. **Michelle Oravitz:** one of those things that they're like, Hmm, this is interesting. I don't know, it was kind of a random side effect of this chemo drug. I dunno if it was a chemo drug or a cancer drug.  **Dr. Nirali Jain:** Yeah.  **Michelle Oravitz:** ever heard of that. **Michelle Oravitz:** So I was just **Dr. Nirali Jain:** I haven't, I mean, that's interesting. I feel like I'd have to look into that because that would be definitely a point of interest for a lot of Reis. But it kind of does go back to the point of, you know, women are really born with all the eggs we're ever gonna have. So it's about a million, and then it just goes down from there. **Dr. Nirali Jain:** And the, by the time you start having periods, I like to kind of show my patients a chart, but you have a couple hundred thousand eggs and you ovulate one egg a month. That's, you know. Able to [00:18:00] progress into a fertilized egg and then into a, an embryo into a baby, um, if that's your goal. But otherwise, patients that are having periods and not trying to actually get pregnant, we're losing hundreds of eggs a month. **Dr. Nirali Jain:** So.  **Michelle Oravitz:** Mm.  **Dr. Nirali Jain:** It's important to kind of think about that decline, and it's important to know that that rate can be faster in patients with cancer, patients with low ovarian reserve. And sometimes when you have the two compounded, that's when a fertility specialist is definitely, you know, in the queue to, to have a discussion with you in terms of what that means and how you can reach your family building goals despite being faced with that, with that challenge. **Michelle Oravitz:** Yeah. **Michelle Oravitz:** I mean, 'cause we know oxidative stress is one of the things that can cause, uh,  **Dr. Nirali Jain:** Yeah, **Michelle Oravitz:** quality eggs, but it's also can cause cancer. **Dr. Nirali Jain:** Yeah, **Michelle Oravitz:** um, similar, you know, like things that really deplete the body could definitely impact. Um, and then what are your thoughts? I know I'm asking you all kinds of random questions, **Dr. Nirali Jain:** I love it. **Michelle Oravitz:** are your thoughts about doing low simulation in certain [00:19:00] circumstances versus high stem? **Michelle Oravitz:** Sometimes people don't respond as well to higher stems.  **Dr. Nirali Jain:** Yeah, that's a great point. I think that it kind of all goes back to creating an individualized protocol. If. A patient's going to a practice and basically just getting a protocol saying, this is our standard. We start with our standard of, you know, I, I think about the standard, which is 300 of the FSH or that pen that you dial up, and then 150 units of that powder vial. **Dr. Nirali Jain:** And we have patients mixing powders all the time, and that's kind of our blanket protocol that we give patients. But that's not really what's happening behind the scenes. And if you're given a protocol that's, and being told, you know, this is kind of what we give to everyone, it's probably not the right fit for you. **Michelle Oravitz:** Yeah, I  **Dr. Nirali Jain:** Um, there are certain patients that respond to a much lower dose and do really, really well, and then some patients that need a much higher dose. Um, and I think it's, that's kind of like the fun part of being an REI of being able to individualize the [00:20:00] protocol to the patient. Um, and I know for a fact there are so many, luckily, you know, we have so many leaders in REI that have been. **Dr. Nirali Jain:** Have dedicated their entire careers to researching these different protocols and how they can help different patients. Um, patients with lower a MH, you know, might benefit from a duo stim protocol, for example. That's kind of the first one that comes to mind, but a protocol where we're using those follicles from the second half of a cycle. **Dr. Nirali Jain:** I would've never thought that those were the follicles that  **Michelle Oravitz:** Oh,  **Dr. Nirali Jain:** would be better than the first half of the cycle,  **Michelle Oravitz:** Wait,  **Dr. Nirali Jain:** but, **Michelle Oravitz:** that. Explain that. Um, because I think that that's kind of a unique  **Dr. Nirali Jain:** mm-hmm.  **Michelle Oravitz:** that I haven't heard of.  **Dr. Nirali Jain:** Yeah, so there's this new day. It's still kind of developing, but um, kind of going back to, you know, what's an individualized protocol? Duo STEM is one of the newer protocols that we've started using. I, I've used it once or twice in patients. Um, but it goes back to the research that shows that you might actually have two different periods of time in a menstrual cycle where you could potentially recruit [00:21:00] follicles. **Dr. Nirali Jain:** You could have a follicular phase where there's a certain cohort of follicles recruited, and then you have a follicle that forms creates a corpus glut.  **Michelle Oravitz:** um, protocols  **Dr. Nirali Jain:** Yep. And then you basically go through the follicular protocol and then a few days after a retrieval, instead of waiting for a new follicular cohort or follicular recruitment from the first half of your menstrual cycle, you actually use the luteal phase and you recruit those follicles that would've actually died off or have been prematurely recruited in a prior cycle. **Dr. Nirali Jain:** So **Michelle Oravitz:** that's So  **Dr. Nirali Jain:** yeah, **Michelle Oravitz:** you just do a similar, I guess, um, medicine,  **Dr. Nirali Jain:** go right back into it.  **Michelle Oravitz:** do the same exact thing, but right after ovulation.  **Dr. Nirali Jain:** Yeah.  **Michelle Oravitz:** Fascinating. That's really interesting.  **Dr. Nirali Jain:** Yeah,  **Michelle Oravitz:** has been your experience with that?  **Dr. Nirali Jain:** I think it's, honestly, it's mixed. Um, so far, you know, our data from fertility and sterility and A SRM, it, it shows support for these DUO STEM [00:22:00] protocols, saying that if patients don't have that great quality of eggs or if they have a very low number, maybe they'd benefit from starting the meds earlier and recruiting follicles. **Dr. Nirali Jain:** A little bit earlier. Um, so we've seen positive results so far. A lot of work to be done in terms of really understanding it. Um, and of course, as a new attending, I have a lot more experience to kind of build on. Um, but I, I have seen success from it. **Michelle Oravitz:** That's fascinating. Are there any other new technologies, like new add-ons, um, that you've seen, that you've found to be really cool or interesting?  **Dr. Nirali Jain:** I think the biggest thing, actually, kind of going back to our whole topic for today is fertility preservation cancer patients. One of the biggest things that I've learned recently is that we used to start fertility, um, patients. You know, only in the beginning of the cycle days, two or three is technically like when most. **Dr. Nirali Jain:** Most clinics, um, start patients, but for our cancer patients, sometimes you don't have that time. You don't wanna wait a full month to [00:23:00] restart, um, your, you know, your menstrual cycle and then do the fertility preservation and then delay chemotherapy a full month. So we started doing what we call random starts. **Dr. Nirali Jain:** So you basically start a patient whenever they come in. You know, it could be the day after your consultation, the day of your consultation. I've kind of seen all of the above. Um, and we've seen really good success with random starts, per se. Um, and we've been doing a lot more of that, where it's not as dependent on where you're at in your cycle. **Michelle Oravitz:** Mm-hmm.  **Dr. Nirali Jain:** Um, obviously there's a difference in outcomes. You might not be a great candidate for it, so definitely it's worth talking to your doctor about it. But it kind of gives relief to our cancer patients where if you have a new cancer diagnosis and you're like, oh, I just finished my period, like, I can't even start a cycle until next month. **Dr. Nirali Jain:** That's not always true. Um, so it's always worth it to go into see a fertility specialist and just get, you know, get the data that you need right away, and then you can make a decision later on. **Michelle Oravitz:** For sure. Um, Yeah. **Michelle Oravitz:** and I wanted to kind of cover a lot of different topics 'cause I know that [00:24:00] some people are gonna wanna hear what you have to say that don't necessarily, or, uh, have cancer. But it is important. I, I think that, you know, if you get to thirties and you haven't gotten married or you don't have a partner, I think it's really important to preserve your fertility in general.  **Dr. Nirali Jain:** Yeah, **Michelle Oravitz:** important thing. And then if you were going through a cancer diagnosis and you decided to preserve your fertility, um, guess more for women because they're eventually going to be thinking about transfers after they go through treatment. So what are some of the things that they would need to consider as far as that goes? **Michelle Oravitz:** Like after the  **Dr. Nirali Jain:** yeah, **Michelle Oravitz:** then they go through the cancer treatments. Um, and then what, how long should they  **Dr. Nirali Jain:** yeah. Like what does it look like? So I've had patients that come back, you know, in my fellowship training I did a, a couple research projects on patients that came back to pursue an embryo transfer, um, after chemotherapy agent. And basically compared them to how they did, um, [00:25:00] compared to patients that didn't have cancer and just froze their embryos or froze their eggs and then came back to pursue a transfer and. **Dr. Nirali Jain:** I think the, the most reassuring thing from the preliminary data that we have is saying that there's no difference in pregnancy rates and no difference in life birth,  **Michelle Oravitz:** Awesome.  **Dr. Nirali Jain:** of whether they had chemotherapy or not. After freezing those eggs and going through fertility preservation.  **Michelle Oravitz:** Amazing.  **Dr. Nirali Jain:** Um, in terms of where your body needs to be, I think the oncologist, we, we wait for their green light. **Dr. Nirali Jain:** We wait for their signal to say, you know, she's safe to carry a pregnancy.  **Michelle Oravitz:** Mm-hmm.  **Dr. Nirali Jain:** And then once we do that, we basically treat you like any other patient. So if you're coming in for a cycle, if you're having periods, then it's reasonable to try a natural cycle protocol, wait for your body to naturally ovulate an egg. **Dr. Nirali Jain:** And instead of obviously hoping that egg will fertilize, we, um, use a corpus luteum. We use the progesterone from the corpus luteum to really support this embryo being implanted into the uterus. Um. Yeah. [00:26:00] And then there's also another side. I mean, some patients don't get their periods back and they always ask like, what if I never get my period back? **Dr. Nirali Jain:** What if I'm just like in menopause because of the chemotherapy agents? And for that, we can start you on a synthetic protocol or basically an estrogen dependent protocol where you take an estrogen pill for a certain number of days. We monitor your lining, then we start progesterone, um, to support your hormones from that perspective instead of relying on your ovaries to release the progesterone that they need, um, and then doing the embryo transfer a few, few days after progesterone starts. **Dr. Nirali Jain:** So there's definitely different protocols depending on where your menstrual health is at after the chemotherapy or after the cancer treatment. Um, but it's important to kind of just know that. That there's options. It doesn't mean that it's the end of the road if you all of a sudden stop getting your period. **Michelle Oravitz:** Yeah, for sure. I mean, 'cause you, technically speaking, you can really control a lot of that. More so for transfers  **Dr. Nirali Jain:** Yep. **Michelle Oravitz:** Retrievals really is kind of like what [00:27:00] eggs you have, what the quality is. But people can be in complete menopause and you guys can still control their cycles for transfer, which is kind of. A huge difference  **Dr. Nirali Jain:** Yeah,  **Michelle Oravitz:** in the  **Dr. Nirali Jain:** exactly. That's exactly right. Yeah. **Michelle Oravitz:** interesting. Any other, um, new, new things that you're, you guys are excited about? I always like to hear about like the new and upcoming things  **Dr. Nirali Jain:** Of course.  **Michelle Oravitz:** actually before, which I thought was fascinating. Yeah.  **Dr. Nirali Jain:** I feel like there's always like updates and, and new data and things like that coming out, but just know, I think it's important for patients to know, like we're constantly, we're, the reason I chose to even pursue this field was because it's new. Right. There's something that we are discovering every day, every year, and that's what makes our, our conferences so important to attend, um, to really just stay up to date. **Dr. Nirali Jain:** Um, but we are, uh, constantly updating our embryology standards, the way we thaw our eggs, and the success rate associated with a thaw and [00:28:00] how we treat our embryos and the media that we use, right? Like, so we're really thinking about the basic science perspective every single day, and that's what makes this field so unique. **Michelle Oravitz:** It is really awesome. And so do you guys specialize specifically on, um. Egg freezing and, and I mean specific fertility preservation in patients that do that have cancer that are going through treatments, do you guys specialize specifically in that? I mean, I know you do range  **Dr. Nirali Jain:** Yeah. Yeah, because it's such a small community, we all have our own niches and we all kind of have our own interests and  **Michelle Oravitz:** Yeah.  **Dr. Nirali Jain:** no like specific training. There are a couple courses that you take that I took in in training as well, just to kind of understand what it sounds like to, I. Council of fertility preservation, patient with and without cancer. **Dr. Nirali Jain:** Um, and then, you know, you kind of just learn by experience and you form a niche for something that you're passionate about. 'cause that's what makes you, you know, really thorough in, in your treatment. [00:29:00] So that's one of my interests. Um, and, but I would say,  **Michelle Oravitz:** training for that. It's just like  **Dr. Nirali Jain:** yeah, **Michelle Oravitz:** just know how to treat that in  **Dr. Nirali Jain:** exactly.  **Michelle Oravitz:** especially if you're interested in doing that.  **Dr. Nirali Jain:** Exactly. That's exactly right. It's kind of, it just comes with the experience comes with your mentors and who you're surrounded by, and everyone kind of helps each other get to that point. But there are several specialists in our practice at RMA that specialize specifically in fertility preservation in cancer patients. **Dr. Nirali Jain:** So we have a close communication with our oncologist and they know who to refer to within the practice because everyone has their own little interests.  **Michelle Oravitz:** Amazing.  **Dr. Nirali Jain:** Yeah. **Michelle Oravitz:** Um, definitely. I, like I said, I really enjoy picking your brain because it's a lot of fun for me. I, I do  **Dr. Nirali Jain:** Totally.  **Michelle Oravitz:** acupuncture, so  **Dr. Nirali Jain:** Yeah, **Michelle Oravitz:** and I, I think that it's just so crazy that our fields don't work together. I mean, we kind of do, but I think, I just feel like it would be so great  **Dr. Nirali Jain:** exactly.[00:30:00]  **Michelle Oravitz:** the expertise because you guys have immense. Benefits like in, in, uh, technology and incredible innovations and, and then the natural aspect of really understanding the, the body. And I, I just think that it would work so amazing together if it was more of like a thing. 'cause it, I know in China they actually combine the two  **Dr. Nirali Jain:** Yeah.  **Michelle Oravitz:** eastern.  **Dr. Nirali Jain:** Yeah, I mean I think that that's so important and there is data that shows, you know, there's actually a recent study that came out just a few weeks ago on the benefits of acupuncture for fertility patients. And we know that, I mean, I recommend it to all of my patients, specifically the day of the embryo transfer. **Dr. Nirali Jain:** We, luckily, we offer it on site at RMA and we have acupuncturists that come in and, and do a session before and after the embryo transfer, and I think. A lot of that is targeted towards stress relief. But I also think that holistically it's important to feel at your best when we're doing something that's so crucial to your, to your health. **Dr. Nirali Jain:** So to really focus on the diet, focus on stress relief, [00:31:00] focus on meditation, yoga, whatever it takes to get to your best wellbeing when you're going through fertility treatments, um, is so important. So I appreciate  **Michelle Oravitz:** Mm-hmm.  **Dr. Nirali Jain:** like you that really specialize in the other side of. Of this, because I do consider it still part of the holistic medicine that we need to really maximize success for our patients. **Michelle Oravitz:** Awesome. Well,  **Dr. Nirali Jain:** Yeah, **Michelle Oravitz:** Jane, this is such a pleasure Of talking to you. You've given us some, so much great information and we've definitely dived into a, do a topic that I don't typically, I haven't yet spoken about. But, um, that being said, it's such an important topic to talk about. And thank you so much for coming on today. **Michelle Oravitz:** Oh,  **Dr. Nirali Jain:** course. **Michelle Oravitz:** I get off, how can people find you?  **Dr. Nirali Jain:** That's a great question. So I have, um, a social media page. I, it's called Expert nc. So like EGG,  **Michelle Oravitz:** I  **Dr. Nirali Jain:** um, expert nc. Try, tried to make it a little bit humorous. Um, but I'm all over social [00:32:00] media and would love to hear from anyone that is listening. I, you know, every, every day I get different, um, dms and I'm happy to respond. **Dr. Nirali Jain:** I love hearing about everyone else's. Stories and things like that. Um, so that is kind of my main, main social media platform. Um, and then through like RMA and Reproductive Medical Associates, we also have a YouTube channel. We have an Instagram page, um, of our office available, um, as well that is public. **Dr. Nirali Jain:** So you can find us pretty easily if you just kind of hit Google. But um, yeah, I'm kind of developing my social media platform as the expert and I hope it grows.  **Michelle Oravitz:** Love it. Great.  **Dr. Nirali Jain:** Yeah.  **Michelle Oravitz:** was such a pleasure talking to you. Thank you. so much **Dr. Nirali Jain:** Thank you. **Michelle Oravitz:** today.  **Dr. Nirali Jain:** Of course. Thank you so much for having me.  [00:33:00]   

Fertility & Sterility on Air brings you a panel discussion from Best of ASRM and ESHRE 2025. Join our host, Dr. Eve Feinberg and the following panelists:  Aleks Rajkovic - 01:04 Henriette Nielsen - 10:09 Thomas Ebner/Sangita Jindal - 20:20 Angela Lawson - 29:24 Antonio Capalbo/Catherine Racowsky - 46:24 Herman Tournaye - 01:02:00

Podcast Alert!

Show Notes: Alison Wakoff Loren went to St Louis to medical school at Washington University. She specialized in internal medicine and later completed a subspecialty fellowship in hematology oncology at the University of Pennsylvania. She met her husband in medical school and they have three children all in their early twenties. Alison  is now the chief of the Division of Hematology Oncology at the University of Pennsylvania, specializing in bone marrow transplantation, a curative therapy for blood cancer. Taking Care of Patients Alison finds the best part of her job to be taking care of patients, especially those who have just been diagnosed with leukemia. She gets to know people when they are in a vulnerable place and understand their lives, which is a privilege. She also does a lot of administrative work, mentoring trainees and faculty, helping them understand their passions and connecting them with opportunities. Alison is proud of her mentoring success stories. She encourages everyone to show gratitude and warmth, as the world is not always generous, and it is important to show that we can make a difference for each other by showing warmth and gratitude. She also shares a story of mentoring a talented MD and PhD candidate who was unhappy in her research role.  Helping Patients with Leukemia Alison discusses the fear and uncertainty people face when discovering they have leukemia. She shares her experiences in delivering sad news to a patient who had been a high school history teacher and had leukemia come back. She mentions that people have incredibly generous spirits and sometimes don't behave their best when they're scared. She also shares examples of people making decisions that matter to their loved ones, such as stopping treatment or continuing treatment when they don't want to. Alison also discusses the range of responses people have when they have to deliver sad news. She explains that most people know they're in for an uphill climb, and it's rare to be surprised. Alison specializes in bone marrow transplants, which are intensive but curative intent therapies, and she emphasizes the importance of laying groundwork ahead of time to make difficult conversations less shocking and offering hope while grounding the conversation. She also stresses the importance of being honest and respectful in her interactions with patients. Fertility Preservation in  Cancer Treatment The conversation turns to Alison's research and the importance of fertility preservation in cancer treatment, which can harm reproductive capacity and lead to infertility. Oncology teams often don't discuss this topic, partly because they are focused on cancer and not reproductive endocrinologists. However, there is a focus on making sure all patients are counseled about the reproductive impact of their treatments and reproductive options to engage in fertility preservation before starting cancer treatments. Alison explains what is recommended for women. She mentions that it is important to discuss these options before starting cancer treatment, as it reduces distress and decision regret for people after treatment. Alison is fortunate to be able to speak and advocate for fertility preservation for people with blood cancers, which represents a special population in oncology care. She has been fortunate to co-chair an effort to develop guidelines for fertility preservation from a large cancer organization. She explains that  colleagues in reproductive science are doing amazing research to extend options for reproductive care before and after cancer treatment, which is exciting to inform oncology clinicians and advocate for insurance coverage for these treatments. Family Life, Running, and Circadian Rhythms Alison shares her experiences with her children, including a daughter who works at the Amherst College Library, an older son considering medical school, and a younger son at Bates College in Maine. Her daughter has inspired her to think about women in the workplace, as she was criticized for not valuing women in her division and for hiring women because they are cheaper. Alison also shares her experience with running, which she enjoys but has to get up early to get in before work. She talks about the concept of morning and night people, stating that people have their own internal clocks. She also mentions that research into the biology of the circadian clock is still in its early stages.  Influential Harvard Courses and Professors Alison shares her experiences at Harvard, including taking courses with Stephen Jay Gould and Dick Lewontin, who were incredibly intelligent and insightful. She also took Act 10 as a senior, which was an unexpected experience that helped her learn different ways of thinking about the subject. Alison  volunteered at the Mission Hill after-school program, which allowed her to get to know the kids and families there. She tried out for various extracurriculars, such as singing and photography, but found it intimidating. She also mentions the training program for photographers. Timestamps: 01:51: Alison Wakoff Loren's Medical Journey  04:12: Motivations and Rewards in Patient Care  22:20: Mentoring Success Stories  22:36: Challenges and Insights in Patient Care  24:17: Balancing Professional and Personal Life  24:32: Research and Advocacy in Fertility Preservation  28:54: Influences and Reflections on Harvard Education  37:25: Extracurricular Activities and Personal Growth  Links: Penn Medicine Website: https://www.pennmedicine.org/providers/profile/alison-loren American Society of Clinical Oncology: https://www.asco.org/ Leukemia and Lymphoma Society: https://www.lls.org/ Featured Non-profit: The featured non-profit of this episode of The 92 Report is recommended by Ming Chen who reports: “ One nonprofit that I've been involved in is the Keswick Foundation, which funds pilot programs in Hong Kong and mainland China to help the community serve needs that are not being met by the government. So we work with family and vulnerable populations. We work with the elderly, and we work with things like helping promote social work in China, as well as clinical psychologists in different NGOs around the region. The other nonprofit that I am on the Advisory Council of is the Asian American foundation, TAF for short, T, A, A, F, F. The Asian American foundation, basically, is a platform that gets together different organizations around anti hate, changing the narrative education, helping to advocate for Asian American history taught in public schools, as well as narrative change representation in Hollywood and beyond. And again, it was founded around the 2020, around the growing disturbing rhetoric against Asians with the rise of COVID So yeah, those are two nonprofit organizations that I'm involved with. So again, one nonprofit that's been on the board for for many, many years is called the Keswick Foundation, and it funds pilot programs in Hong Kong as well as Mainland China. And then the Asian American foundation. If you want to learn more about the Asian American foundation, it's www dot T, A, A, f.org, check it out.” To learn more about their work, visit:  The Asian American Foundation: https://www.taaf.org/ The Keswick Foundation: https://www.keswickfoundation.org.hk/    

Are you wondering whether freezing eggs or embryos is the better choice for fertility preservation? How has freezing technology changed and advanced? What are the ethical, financial, and emotional factors behind this important decision? In this episode of Brave and Curious, host Dr. Lora Shahine takes a deep dive into the complex and personal decision of egg vs. embryo freezing. With a thoughtful look at the evolution of fertility preservation, she compares past practices with today's cutting-edge technologies, helping listeners understand how far the field has come and what options are now available. You'll gain a better understanding of the pros and cons of freezing eggs versus embryos, including important medical, ethical, and legal factors. Dr. Shahine also explores possible future challenges—like legal disputes over embryo use—and breaks down the financial costs and access issues involved. You may be surprised by some of the tips and will finish the episode better informed about your choices. In this episode you'll hear: [0:16] Eggs vs. Embryos [1:11] Advancements in freezing technology [4:33] Egg freezing: pros & cons [9:08] Embryo freezing: pros & cons [11:19] Final thoughts   Dr. Shahine's Weekly Newsletter on Fertility News and Recommendations Follow @drlorashahine Instagram | YouTube | Tiktok | Her Books

There is a California law requiring most health insurers to cover fertility preservation before medical treatments that can cause infertility. Unfortunately learning about coverage is not a guarantee. SB 600

In this episode,Abby Eblen MD from Nashville Fertility Center, Susan Hudson MD from Texas Fertility Center, and Carrie Bedient MD from the Fertility Center of Las Vegas talk with Lauren Roth, MD who is the Medical Director of the Shady Grove Rockville Fertility Center. During the podcast we discuss the benefits of egg freezing. We explore who might consider freezing their eggs, the ovarian stimulation process, and how frozen eggs can be used in the future. Our conversation covers ovarian reserve, the advantages of freezing eggs at a younger age versus after 35, and the monitoring process before egg retrieval, including AMH, antral follicle count, FSH, and estrogen levels. We also walk through what happens when a woman returns to use her frozen eggs to create embryos for conception. Tune in for an informative discussion on this important fertility option!This episode was brought to you from ReceptivaDx and Shady Grove Fertility.

Ashley Chukwu is a 30-year-old food and wine blogger in Atlanta, living her life without the prospect of building a family soon. So, when her mom suggested she consider freezing her eggs, Ashley decided to do some research. At the time, she knew little about the process or whether her insurance would cover it. That's when she discovered her employer, Peraton offered fertility preservation through Progyny.  In this episode, Ashley shares her journey—from researching the process and navigating her benefits to handling injections and undergoing the procedure. She discusses challenges along the way, the importance of representation, and reflects on the peace of mind she's gained from taking control of her fertility.  Tune in to hear Ashley's experience and learn how support from her company helped her make a decision that aligns with her goals and lifestyle.  Guest: Ashley Chukwu, MPH, Progyny Member at Peraton  Host: Dan Bulger, Progyny   For more information, visit Progyny's Podcast page and Progyny's Education page for more resources. Be sure to follow us on Instagram, @ThisisInfertilityPodcast and use the #ThisisInfertility. Have a question, comment, or want to share your story? Email us at thisisinfertility@progyny.com.