Podcasts about Feasibility

Twenty science stories from 2025 that you might have missed! The asteroid that's NOT going to hit earth. Exploring protein localization. Probing the sun. Pursuing nuclear fusion. ADHD and life expectancy. Sleeplessness and heart disease. Evolution of potatoes from tomatoes. New moons in our solar system. Exoplanet discoveries. The new human organelle. The Turing Test is passed. Feasibility of geoengineering. Influence of microbiome on infant brain development. Effect of COVID19 in male fathers on their offspring. A link between the common cold and COVID-19. Ocean acidification and environmental thresholds. Life on other planets. Pig organs successfully transplanted into people. Advances in synthesizing antimatter. Then hear about the planets, meteors, stars, nebulae, and constellations we can see in the night sky in January. ‘Bench Talk: The Week in Science' is a weekly program that airs on WFMP Louisville FORward Radio 106.5 FM (forwardradio.org) every Monday at 7:30 pm, Tuesday at 11:30 am, and Wednesday at 7:30 am. Visit our Facebook page for links to the articles discussed in this episode: https://www.facebook.com/BenchTalkRadio

In this conversation, Davidson, a Bitcoin developer, discusses his project Floresta, which aims to provide a lightweight Bitcoin node solution that balances privacy, security, and usability. He explains the technical aspects of Floresta, including its architecture, the use of compact block filters, and its relationship with Utreexo. Davidson emphasizes the importance of making Bitcoin more accessible to non-technical users while maintaining security and privacy. The discussion also touches on the challenges of running Bitcoin nodes, the potential integration of Floresta with existing applications, and the future of Bitcoin technology.Takeaways:

I speak with Mike Konnert, President & CEO of Vizsla Silver (NYSE/TSX: VZLA) about the company's upsized US$300M convertible note financing and how it strengthens Vizsla's ability to accelerate development of the high-grade Panuco Project, in Mexico. Mike also highlights the newly filed feasibility study, underground progress, and Vizsla's long-term goal of becoming a 50 Moz AgEq/year producer. Key Discussion Points Why Vizsla Chose the $300M Convertible Note Replacing a costlier, restrictive project finance facility with a flexible, upfront funding structure. Capped-Call = Minimal Dilution Protection up to US$10.50/share, with the company intending to settle in cash. Accelerating Build-Out & Exploration Immediate capital access enables faster construction, underground drilling, and district-wide exploration. Feasibility & Outlook Vizsla is now fully feasible and fully financed with exceptional project economics and multiple growth targets across Panuco. If you have any follow up questions for Mike please email me at Fleck@kereport.com.    Click here to visit the Vizsla website to learn more about the Company.   -------------- For more market commentary & interview summaries, subscribe to our Substacks: https://kereport.substack.com/ https://excelsiorprosperity.substack.com/ Investment disclaimer: This content is for informational and educational purposes only and does not constitute investment advice, an offer, or a solicitation to buy or sell any security. Investing in equities and commodities involves risk, including the possible loss of principal. Do your own research and consult a licensed financial advisor before making any investment decisions. Guests and hosts may own shares in companies mentioned.

In this episode of the Real Estate Pros podcast, host Michelle Kesil interviews Eugene Gershman, a development management expert. Eugene discusses how he helps property owners develop their land into profitable ventures, emphasizing the importance of understanding zoning laws, conducting feasibility studies, and managing risks. He shares insights on client engagement, the role of technology in streamlining processes, and the investment opportunities available in real estate development. Eugene also highlights the significance of building a qualified team and maintaining open communication with clients throughout the development process.   Professional Real Estate Investors - How we can help you: Investor Fuel Mastermind:  Learn more about the Investor Fuel Mastermind, including 100% deal financing, massive discounts from vendors and sponsors you're already using, our world class community of over 150 members, and SO much more here: http://www.investorfuel.com/apply   Investor Machine Marketing Partnership:  Are you looking for consistent, high quality lead generation? Investor Machine is America's #1 lead generation service professional investors. Investor Machine provides true 'white glove' support to help you build the perfect marketing plan, then we'll execute it for you…talking and working together on an ongoing basis to help you hit YOUR goals! Learn more here: http://www.investormachine.com   Coaching with Mike Hambright:  Interested in 1 on 1 coaching with Mike Hambright? Mike coaches entrepreneurs looking to level up, build coaching or service based businesses (Mike runs multiple 7 and 8 figure a year businesses), building a coaching program and more. Learn more here: https://investorfuel.com/coachingwithmike   Attend a Vacation/Mastermind Retreat with Mike Hambright: Interested in joining a "mini-mastermind" with Mike and his private clients on an upcoming "Retreat", either at locations like Cabo San Lucas, Napa, Park City ski trip, Yellowstone, or even at Mike's East Texas "Big H Ranch"? Learn more here: http://www.investorfuel.com/retreat   Property Insurance: Join the largest and most investor friendly property insurance provider in 2 minutes. Free to join, and insure all your flips and rentals within minutes! There is NO easier insurance provider on the planet (turn insurance on or off in 1 minute without talking to anyone!), and there's no 15-30% agent mark up through this platform!  Register here: https://myinvestorinsurance.com/   New Real Estate Investors - How we can work together: Investor Fuel Club (Coaching and Deal Partner Community): Looking to kickstart your real estate investing career? Join our one of a kind Coaching Community, Investor Fuel Club, where you'll get trained by some of the best real estate investors in America, and partner with them on deals! You don't need $ for deals…we'll partner with you and hold your hand along the way! Learn More here: http://www.investorfuel.com/club   —--------------------

Marty, Dave, Eric, and Daniel sort the rumor of a black AVP, tools for creating spatial video, and maybe Netflix on AVP.VisionOS 26.2 RChttps://developer.apple.com/documentation/visionos-release-notes/visionos-26_2-release-notes New Immersive VideoThe World of Red Bullhttps://tv.apple.com/us/show/world-of-red-bull/umc.cmc.h96ns9ovu03p34i6bnodn3h6 Legs of Steel Crew video on the shoothttps://www.facebook.com/watch/?v=845919234692119 Winners of App and Game of the yearExplore POVhttps://apps.apple.com/ca/app/explore-pov/id6479555991Porta Nubahttps://apps.apple.com/ca/app/porta-nubi-immersive-puzzles/id6503628155 Back in BlackMore All-Black Vision Pro Prototype Parts Surface Onlinehttps://forums.macrumors.com/threads/more-all-black-vision-pro-prototype-parts-surface-online.2474341/ New startup competitionEx Apple Engineer's New Startup Claims to Beat Vision Pro in Speedhttps://www.macobserver.com/news/ex-apple-engineers-new-startup-claims-to-beat-vision-pro-in-speed/ Lakers in 3D!!!!Apple Immersive to stream select Lakers games on Vision Prohttps://www.thesportingtribune.com/2025/12/04/apple-immersive-to-broadcast-select-lakers-gamesSteam FrameConfirmed: Steam Frame will lack this Apple Vision Pro and Meta Quest feature at launch — Valve says it's 'on our list'https://www.tomsguide.com/computing/vr-ar/confirmed-steam-frame-will-lack-this-apple-vision-pro-and-meta-quest-feature-at-launch-valve-says-its-on-our-list Bad Medicine Assessing the Feasibility of Using Apple Vision Pro While Performing Medical Precision Tasks: Controlled User Studyhttps://pubmed.ncbi.nlm.nih.gov/41340843/ Video creation trainingsApple Vision Pro Strategy For Immersive Video Production: Live Sports, Static Foveation, And Monetization Challengeshttps://www.cined.com/apple-vision-pro-strategy-for-immersive-video-production-live-sports-static-foveation-and-monetization-challenges/Create stories with immersive video and audio | Meet with Applehttps://www.youtube.com/watch?v=jK58gKCyyBgAn introduction to capturing Apple Immersive Video | Meet with Applehttps://www.youtube.com/watch?v=ghpBTIbTZlg Day 1 | Create immersive media experiences for visionOS | Meet with Applehttps://www.youtube.com/watch?v=leGqoF8HJxU Day 2 | Create immersive media experiences for visionOS | Meet with Applehttps://www.youtube.com/watch?v=4V_7-1bm4Rk Hidden workflow resourcesVision Pro Hidden Features and Workflows Many Users Haven't Discoveredhttps://applemagazine.com/vision-pro-hidden-features/Hyper-Specific Apple Vision Pro Use Cases Emerging Among Early Adoptershttps://applemagazine.com/vision-pro-hyper-specific-use-cases/ ReviewsI wish I waited for Galaxy XR instead of going broke on Vision Prohttps://www.androidauthority.com/i-wish-i-waited-samsung-galaxy-xr-3617651/Apple Vision Pro (M5) Review After 30 Days of Real Usehttps://www.geeky-gadgets.com/apple-vision-pro-m5-review-after-30-days-of-real-use/Drone for Spatial VideoThis 8K 360 Drone Is Not What I Expected - Antigravity A1 50-Min Reviewhttps://www.youtube.com/watch?v=MipoNX7X0mA House of CommonsApple Vision Pro appears in front of House of Commons Select Committeehttps://www.reddit.com/r/VisionPro/comments/1pckcsp/apple_vision_pro_appears_in_front_of_house_of/ Netflix and chillA guide: How to watch Netflix in 4K on Safari or Supercut, with Spatial Audiohttps://www.reddit.com/r/VisionPro/comments/1pc2zm6/a_guide_how_to_watch_netflix_in_4k_on_safari_or/ Netflix Apphttps://www.reddit.com/r/VisionPro/comments/1pevsr6/netflix_app/ APPS Santa's Village: Holiday Magichttps://apps.apple.com/us/app/santas-village-holiday-magic/id6755688257 Posters 2.0https://apps.apple.com/us/app/posters-discover-media-home/id6478062053Email: ThePodTalkNetwork@gmail.comWebsite: ThePodTalk.netYouTube.com/@VisionProFiles

Freelance copywriting with AI? Is that smart? Not so savvy? And, where does strategy data and analysis fit in? We (re)define what strategy really is and how you see yourself. We talk about: AI (and its role in data analysis) Storytelling What you can promise clients (and what you should never)!   Take Kirsty's assessment to pinpoint your communication style, and get personalized insight on where you excel, where you could improve, and some strategies to try this week.   Join Amy's newsletter and get weekly insights on how to build and grow a sustainable business that fills your coffers and feeds your soul.  Got a question? Click here to ask us!

Inato: https://go.inato.com/3VnSro6CRIO: http://www.clinicalresearch.ioMy PatientACE recruitment company: https://patientace.com/Join me at my conference! http://www.saveoursites.comText Me: (949) 415-6256Listen on Spotify: https://open.spotify.com/show/7JF6FNvoLnBpfIrLNCcg7aGET THE BOOK! https://www.amazon.com/Comprehensive-Guide-Clinical-Research-Practical/dp/1090349521/ref=sr_1_1?keywords=Dan+Sfera&qid=1691974540&s=audible&sr=1-1-catcorrText "guru" to 855-942-5288 to join VIP list!My blog: http://www.TheClinicalTrialsGuru.comMy CRO and Site Network: http://www.DSCScro.comMy CRA Academy: http://www.TheCRAacademy.comMy CRC Academy: http://www.TheCRCacademy.comLatinos In Clinical Research: http://www.LatinosinClinicalResearch.comThe University Of Clinical Research: https://www.theuniversityofclinicalresearch.com/My TikTok: DanSfera

In this episode, Jason and Makenzie dive into the real purpose of ESOP feasibility and why it's far more than just another spreadsheet. They break down what “feasibility” truly means in an ESOP transaction and walk through the key factors companies should evaluate, from existing debt to entity structure (S-corp vs. C-corp) to long-term sustainability. They also dig into how feasibility helps determine whether an ESOP will genuinely benefit the company, the owners, and the employees.

Comment on the Show by Sending Mark a Text Message.What happens when the biggest workplace experiment in modern history becomes admissible evidence? Five years after COVID reshaped how we work, we take a clear-eyed look at remote work's legacy—what it proved, who it protected, and why some employers are trying to forget the results. We trace the arc from lifeline to legal battleground, exposing how rigid return-to-office policies are pushing out the very people who kept companies alive: disabled workers, pregnant employees, caregivers, and older staff who thrived with reasonable flexibility.We dig into the details behind the headlines, from constructive discharge tactics and moving performance goalposts to the tech-driven surveillance that quietly captured mountains of unpaid labor. Along the way, we unpack real cases, including a federal jury award tied to remote feasibility and disability rights, and a new Manhattan complaint alleging revoked flexibility and weaponized metrics. The throughline is simple: when the work got done from home—consistently and measurably—that record matters. Blanket policies that ignore it aren't just shortsighted; they carry legal risk.Beyond the courtrooms, we talk about what ethical, effective design looks like now. Location should map to duties and outcomes, not vibes or nostalgia. Feasibility analyses, transparent criteria, and outcome-based metrics create clarity for teams while honoring the realities of health, parenting, and aging. Remote work is not a luxury for many; it is the difference between employment and exit, stability and crisis. If the experiment proved anything, it is that millions delivered under extraordinary strain—and that proof deserves respect.If this conversation resonates, follow the show, share it with a friend who needs the receipts, and leave a rating or review so more people can find it. Your stories shape where we take this next—what's your reality with remote, hybrid, or RTO? If you enjoyed this episode of the Employee Survival Guide please like us on Facebook, Twitter and LinkedIn. We would really appreciate if you could leave a review of this podcast on your favorite podcast player such as Apple Podcasts. Leaving a review will inform other listeners you found the content on this podcast is important in the area of employment law in the United States. For more information, please contact our employment attorneys at Carey & Associates, P.C. at 203-255-4150, www.capclaw.com.Disclaimer: For educational use only, not intended to be legal advice.

Caledonia mining CEO Mark Learmonth joined Steve Darling from Proactive to discuss the company's decision to formally proceed with the development of the Bilboes gold project in Zimbabwe, following the completion of a comprehensive feasibility study. The long-awaited study confirmed the project's compelling economics and positioned Bilboes as one of the most significant future gold developments in the region. Learmonth highlighted that the project delivers an NPV of more than $580 million at an 8% discount rate, based on a gold price assumption of $2,548 per ounce. The internal rate of return exceeds 32%, supported by a competitive all-in sustaining cost of $1,061 per ounce. “That clearly means that it's a very high-margin operation with a very quick payback period,” Learmonth told Proactive. The feasibility study recommends developing Bilboes as a single-phase, large-scale operation, with peak capital expenditure estimated at $484 million, plus roughly $100 million in financing-related costs. According to Learmonth, the single-phase plan generates superior returns compared to a phased development approach, benefiting from economies of scale and stronger overall project metrics. Caledonia expects to fund the build primarily through a combination of non-recourse senior debt and internal equity from Blanket Mine, which is set to support the financing through a newly arranged three-year gold hedge at a minimum strike price of $3,500 per ounce. This hedge is anticipated to generate approximately $200 million in cash flow to underpin project construction. Looking ahead, Learmonth outlined a timeline that sees construction beginning in the second half of 2026, with first gold production targeted for late 2028, contingent on finalising debt agreements. The company also plans to deliver further exploration updates from Blanket and Motapa in early 2026, adding additional potential growth catalysts. Beyond its economic strength, Bilboes represents a major milestone for Zimbabwe's mining sector. Learmonth described it as a “marquee project” with the potential to meaningfully boost national gold production, attract new investment, and reinforce the country's profile as a destination for world-class gold development. #proactiveinvestors #aim #cmcl #nyseamerican #cmcl #caledoniamining #GoldInvesting #MiningStocks #ZimbabweMining #BilboesProject #GoldProduction #FeasibilityStudy #MiningDevelopment #JuniorMining #MiningEconomics #GoldPrice #ResourceInvestment

Nathan dives into the most crucial skill for success in residential development: mastering feasibility. He stresses that running feasibility isn't about expense, but time investment, and that poorly run feasibility studies are the biggest pressure builder and cause of project failure.Learn why feasibility is both an art and a science and how it encompasses not just the financial numbers, but also buildability, compliance, and factoring in all project time frames (approvals, build, and sales). Nathan strongly advises aspiring developers to become laser-focused specialists in a small, proven area and to continually "flex that feasibility muscle" by testing both successful and unsuccessful sites. By doing the hard reps behind the scenes, you gain the insider knowledge to make calculated risks and secure the best deals.Topics: ✅ Feasibility: Art and Science ✅ Project Failure Point ✅ Avoid Emotional Investing ✅ Become a Laser Specialist ✅ The Feasibility Muscle ✅ Time Frames are KeyConnect with Nathan Battishall: LinkedIn: https://www.linkedin.com/in/nathanbattishall/Website: https://duplexbuildingdesign.com/ Hosted on Acast. See acast.com/privacy for more information.

Most people jump to what something looks like in practice (to assess viability and feasibility), but the first test to pass relates to desirability.Was this helpful? If so then you need to check out the 7 Fundamentals Of Self Improvement which features short summaries of the most popular and impactful episodes from the past 7 years.Takes only 5 minutes to read through them today but it'll help you avoid years of making things so much harder than they need to be. Plus, I bet you'll be surprised to learn what they are...

In deze derde aflevering van onze serie over de Novum innovatiemethode duiken Jeroen en Marijn in fase 3: Experimenteren. Deze fase wordt vaak beschouwd als de belangrijkste stap in het hele innovatieproces, omdat je hier voor het eerst echt ontdekt of je op de juiste weg zit. Leer hoe je ideeën niet alleen bedenkt en uitwerkt, maar vooral hoe je test of ze daadwerkelijk het probleem oplossen dat je eerder hebt geïdentificeerd.Marijn deelt praktische inzichten over het testen van drie kernvragen: Is je oplossing wenselijk voor de gebruiker? Is het technisch en organisatorisch mogelijk? En heeft het genoeg effect om de investering waard te zijn? Daarnaast bespreken we het gevaar van 'non-problemen' - situaties waarbij een gebruiker denkt een probleem te hebben, maar de oplossing uiteindelijk minimale waarde oplevert. Met concrete voorbeelden uit de praktijk, zoals een zoekmachine-experiment, leer je hoe je experimenten structureert en wanneer je moet kiezen tussen doorgang (persevere), herontwerp (pivot) of stoppen (kill).Key Takeaways:✓ Waarom experimenteren de cruciale fase is in innovatieprojecten✓ De drie kernvragen: wenselijk, mogelijk, en effectvol✓ Het verschil tussen echte problemen en non-problemen✓ Hoe je experimenten structureert met duidelijke aannames en succescriteria✓ Wanneer je moet stoppen met experimenteren en door moet naar implementatie✓ Praktisch voorbeeld: A/B testing van zoekmachines bij een overheidsorganisatie✓ Tools: Experiment Canvas en Interview-analyse templatesResources vermeld in deze aflevering:Novum Innovatiemethode documentatie (www.svb.nl/innovatie)Experiment Canvas templateInterview-analyse Excel template (verkrijgbaar via innovatie@svb.nl)Viability, Feasibility, Desirability framework

Vizsla Silver just released its Feasibility Study for the Panuco Project (Nov 12). Mike Konnert, President & CEO of Vizsla Silver (TSX:VZLA, NYSE:VZLA),  walks through the headline economics, funding, growth runway, and permitting path. Feasibility Results: After-tax NPV US$1.8B, IRR 111%, AISC ~US$10.61/oz, and payback in ~7 months. Driven by low upfront capital and strong margins. Capital & Funding: Capex US$238M (net ~US$173M). Fully funded with US$200M cash, US$220M Macquarie facility, and ~US$40M in equities. Mine Plan & Upside: Only 12.8Mt of the ~25Mt global resource used in reserves. Large potential for conversion and expansion near Napoleon, Copala, and La Luisa. District Growth: Ongoing drilling with four rigs targeting Animas, Santa Fe, and additional veins for long-term expansion. Sensitivity & Strength: Even at US$17 Ag and US$1,550 Au, NPV US$460M, IRR 42%. Permitting & Build: Fully engineered, test mining underway, and permits expected mid-2026. Ready to build once granted. Valuation & Outlook: Trading near 0.5× NAV with potential re-rating as it advances to production. Targeting 50Moz AgEq/yr within 10 years. If you have any follow up questions for Mike please email me at Fleck@kereport.com.   Vizsla Silver will be hosting a webcast to discuss the Panuco Project Feasibility Study at 10:00 am PT (1:00 pm ET) on November 24th.  To register, please click here   ---------- For more market commentary & interview summaries, subscribe to our Substacks: https://kereport.substack.com/ https://excelsiorprosperity.substack.com/ Investment disclaimer: This content is for informational and educational purposes only and does not constitute investment advice, an offer, or a solicitation to buy or sell any security. Investing in equities and commodities involves risk, including the possible loss of principal. Do your own research and consult a licensed financial advisor before making any investment decisions. Guests and hosts may own shares in companies mentioned.

Vizsla Silver announced a strong Feasibility Study for its 100%-owned Panuco silver-gold project in Sinaloa, Mexico. Arizona Sonoran Copper has secured a C$75 million bought-deal financing led by Canaccord Genuity to advance early development work at its Cactus Copper Project near Casa Grande, Arizona. Dryden Gold reported final 2025 drill results from its Elora Gold System, where the company has more than tripled the length of the main Elora Shear Zone to over 800 metres. NexGen Energy released outstanding assays from its Patterson Corridor East discovery, located 3.5 kilometers east of the company's flagship Arrow deposit in Saskatchewan's Athabasca Basin. Osisko Metals reported strong new drilling from its Gaspé Copper Project in eastern Québec, including long intercepts that both confirm and extend mineralization beyond the 2024 resource model. Brixton Metals released additional strong assays from the Trapper Gold Target at its Thorn Project in British Columbia's Golden Triangle. Borealis Mining reported its second gold and silver doré pour from ongoing heap-leach operations at its Borealis mine in Nevada.This episode of Mining Stock Daily is brought to you by… EQUINOX GOLDEquinox has recently completed the business combination with Calibre Mining to create an Americas-focused diversified gold producer with a portfolio of mines in five countries, anchored by two high-profile, long-life Canadian gold mines, Greenstone and Valentine. Learn more about the business and its operations at ⁠⁠⁠⁠⁠⁠equinoxgold.com⁠⁠⁠⁠⁠⁠

Karim Harbott: From Requirements Documents to Customer Obsession—Redefining the PO Role Read the full Show Notes and search through the world's largest audio library on Agile and Scrum directly on the Scrum Master Toolbox Podcast website: http://bit.ly/SMTP_ShowNotes. The Great Product Owner: Strategic, Customer-Obsessed, and Vision-Driven   "The PO role in the team is strategic. These POs focus on the customer, outcomes, and strategy. They're customer-obsessed and focus on the purpose and the why of the product." - Karim Harbott   Karim believes the industry fundamentally misunderstands what a Product Owner should be. The great Product Owners he's seen are strategic thinkers who are obsessed with the customer. They don't just manage a backlog—they paint a vision for the product and help the entire team become customer-obsessed alongside them.  These POs focus relentlessly on outcomes rather than outputs, asking "why are we building this?" before diving into "what should we build?" They understand the purpose of the product and communicate it compellingly.  Karim references Amazon's "working backwards" approach, where Product Owners start with the customer experience they want to create and work backwards to figure out what needs to be built. Great POs also embrace the framework of Desirability (what customers want), Viability (what makes business sense), Feasibility (what's technically possible), and Usability (what's easy to use). While the PO owns desirability and viability, they collaborate closely with designers on usability and technical teams on feasibility.  This is critical: software is a team sport, and great POs recognize that multiple roles share responsibility for delivery. Like David Marquet teaches, they empower the team to own decisions rather than dictating every detail. The result? Teams that understand the "why" and can innovate toward it autonomously.   Self-reflection Question: Does your Product Owner paint a compelling vision that inspires the team, or do they primarily manage a list of tasks? The Bad Product Owner: The User Story Writer "The user story writer PO thinks it's their job to write full, long requirements documents, put it in JIRA, and assign it to the team. This is far away from what the PO role should be." - Karim Harbott   The anti-pattern Karim sees most often is the "User Story Writer" Product Owner. These POs believe their job is to write detailed requirements documents, load them into JIRA, and assign them to the team. It's essentially waterfall disguised as Agile—treating user stories like mini-specifications rather than conversation starters. This approach completely misses the collaborative nature of product development.  Instead of engaging the team in understanding customer needs and co-creating solutions, these POs hand down fully-formed requirements and expect the team to execute without question. The problem is that this removes the team's ownership and creativity. When POs act as the sole source of product knowledge, they become bottlenecks.  The team can't make smart tradeoffs or innovate because they don't understand the underlying customer problems or business context. Using the Desirability-Viability-Feasibility-Usability framework, bad POs try to own all four dimensions themselves instead of recognizing that designers, developers, and other roles bring essential perspectives. The result is disengaged teams, slow delivery, and products that miss the mark because they were built to specifications rather than shaped by collaborative discovery. Software is a team sport—but the User Story Writer PO forgets to put the team on the field.   Self-reflection Question: Is your Product Owner engaging the team in collaborative discovery, or just handing down requirements to be implemented?   [The Scrum Master Toolbox Podcast Recommends]

Description Join host and HRS Digital Education Committee Chair Michael S. Lloyd, MD, FHRS and his guests Miguel A. Leal, MD, FHRS, and Jason T. Jacobson, MD, FHRS, live at HRX 2025. In this prospective series of 12 device-naïve patients (median LVEF ~30%), the authors attempted permanent implantation of a single-coil DF-4 ICD lead into the left bundle branch area (LBBA). They achieved successful implantation with adequate sensing and pacing in 75% of patients, and during short-term follow-up the lead and RV parameters remained stable; minor complications occurred in ~25% of patients (lead micro-dislodgment and septal perforations). The authors conclude that LBBA ICD lead implantation is feasible with current tools and acceptable short-term outcomes, but note the higher-than-expected minor complication rate and emphasize the need for dedicated toolkits, higher operator volume, and a procedural learning curve. Learning Objectives Describe the procedural feasibility, safety considerations, and short-term outcomes associated with left bundle branch area (LBBA) DF-4 defibrillator lead implantation. Identify key technical caveats and patient selection factors relevant to adopting this emerging pacing strategy in clinical practice. Article Information Permanent Left Budnle Branch Area DF-4 Debibrillator Lead Implantation Feasibility, Procedural Caveats, Safety, and Follow-Up Article Authors Anindya Ghosh, Chenni S. Sriram, Nibin Manu, Mullasari Ajit Sankaradas, Gaurav M. Upadhyay, Ulhas M. Pandurangi  Podcast Contributors Michael S. Lloyd, MD, FHRS  Jason T. Jacobson, MD, FHRS  Miguel A. Leal, MD, FHRS  All relevant financial relationships have been mitigated. Host Disclosure(s): M. Lloyd •Speaking/Teaching/Consulting: Medtronic, Arga Medtech, Circa Scientific   •Membership on Advisory Committees: Boston Scientific   ​Contributor Disclosure(s):    J. Jacobson •Stocks, Privately Held: Atlas 5D •Honoraria/Speaking/Teaching/Consulting: Zoll Medical Corporation, Vektor Medical, Inc. •Research: Abbott Medical, CardioFocus, Inc. M. Leal •Speaking/Teaching/Consulting: Medtronic   Staff Disclosure(s) (note: HRS staff are NOT in control of educational content. Disclosures are provided solely for full transparency to the learner): S. Sailor: No relevant financial relationships with ineligible companies to disclose.

Amanda and Ash interview Charlie Kao. Charlie shares how growing up as “free labor” on his dad's properties eventually led him back into commercial real estate, where he's now best known for self-storage. He explains why he's cautious on self-storage at a national level, how overbuilding and new alternatives are changing demand, and why he's leaning into highly localized markets where he has an unfair advantage. Charlie also walks through innovative ways he's turning basic storage into a true service business, from accepting and placing medical shipments to offering boat/RV add-ons, all while using feasibility studies and data-driven pricing to stay ahead of the competition. Charlie KaoCurrent role: Principal and Asset Manager, Twin Oaks CapitalBased in: Grand Rapids, Michigan Say hi to them at: https://www.twinoakscap.com/ | LinkedIn Alternative Fund IV is closing soon and SMK is giving Best Ever listeners exclusive access to their Founders' Shares, typically offered only to early investors. Visit smkcap.com/bec to learn more and download the full fund summary. Join the Best Ever Community  The Best Ever Community is live and growing - and we want serious commercial real estate investors like you inside. It's free to join, but you must apply and meet the criteria.  Connect with top operators, LPs, GPs, and more, get real insights, and be part of a curated network built to help you grow. Apply now at ⁠www.bestevercommunity.com⁠ Podcast production done by ⁠Outlier Audio⁠ Learn more about your ad choices. Visit megaphone.fm/adchoices

In this episode of the PRS Global Open Keynotes Podcast, Dr. Antonio Distefano discusses his review of deep plane facelift cases. The deep plane facelift has gained popularity in recent years, however it may not be optimal for some patients, leading to early recurrence of soft tissue ptosis.   This episode discusses the following PRS Global Open article: "Feasibility and Current Applications of the Symani Surgical System: A Systematic Review" by Giuseppe Colombo, Andrea Dotto and Antonio Distefano. Read it for free on PRSGlobalOpen.com: https://journals.lww.com/prsgo/fulltext/2025/06000/critical_review_of_a_series_of_78_surgical_facial.70.aspx Dr. Antionio Distefano is a plastic surgeon with practices at the Rigenera Clinic in Milan and Canary Islands in Spain. Your host, Dr. Damian Marucci, is a board-certified plastic surgeon and Associate Professor of Plastic Surgery at the University of Sydney in Australia. #PRSGlobalOpen; #KeynotesPodcast; #PlasticSurgery; Plastic and Reconstructive Surgery- Global Open The views expressed by hosts and guests are their own and do not necessarily reflect the official policies or positions of ASPS.

In today's episode, we're joined by Jeff Court, CEO of Tungsten West, the company redeveloping the Hemerdon tungsten project in Devon, UK Jeff's worked on mining projects all over the world, and we'll be talking about his journey into leadership, why tungsten is such a critical mineral, and what it takes to bring a historic mine back into production. We'll also cover the company's new feasibility study, financing challenges, and what the EU Critical Raw Materials Act means for Hemerdon. KEY TAKEAWAYS Tungsten is classified as a critical mineral due to its unique properties, such as high density and tensile strength, making it essential in various industries, including mining, construction, transportation, and defence. Tungsten West requires approximately $93 million to restart production at the Hemerdon project, with funding expected to come from a combination of debt and equity. The feasibility study indicates a strong economic outlook, with a potential internal rate of return (IRR) of around 48%. The project incorporates modern mining practices focused on sustainability, including noise reduction measures and community engagement to ensure compliance with environmental standards and to maintain good relations with local residents. The Hemerdon project has been designated as a strategic project under the EU Critical Raw Materials Act, which enhances its profile and may facilitate access to government-backed funding BEST MOMENTS "Tungsten's not gold, it's not iron ore, it's a very interesting specialty metal space that also has a lot of off-take supply requirements around it too."  "We have about a 12-month period before we start production."  "It raises profile, certainly... it solidifies our credentials."  "We want to be a good neighbour. We're going to be there a minimum of 40 years."  VALUABLE RESOURCES Mail:        ⁠rob@mining-international.org⁠ LinkedIn: ⁠https://www.linkedin.com/in/rob-tyson-3a26a68/⁠ X:              ⁠https://twitter.com/MiningRobTyson⁠  YouTube: ⁠https://www.youtube.com/c/DigDeepTheMiningPodcast⁠  Web:        ⁠http://www.mining-international.org⁠ GUEST SOCIALS  X - @TungstenWest https://x.com/TungstenWest LinkedIn - @ Tungsten West plc https://www.linkedin.com/company/tungsten-west-plc/ Facebook - Tungsten West plc https://www.facebook.com/tungstenwest/ Website: https://www.tungstenwest.com/  Contact: TungstenWest@blytheray.com CONTACT METHOD ⁠rob@mining-international.org⁠ ⁠https://www.linkedin.com/in/rob-tyson-3a26a68/⁠ Podcast Description Rob Tyson is an established recruiter in the mining and quarrying sector and decided to produce the “Dig Deep” The Mining Podcast to provide valuable and informative content around the mining industry. He has a passion and desire to promote the industry and the podcast aims to offer the mining community an insight into people's experiences and careers covering any mining discipline, giving the listeners helpful advice and guidance on industry topics.  This Podcast has been brought to you by Disruptive Media. https://disruptivemedia.co.uk/

Supported by:Accelerating Impact - an independent non-profit advancing impact finance by mobilizing capital toward sustainable development and running free accelerator programs for emerging fund managers (ICFA, ISFA). Join for expert coaching, training, financial support, and a strong peer community. Apply here.***

In this episode of the PRS Global Open Keynotes Podcast, A/Prof Sydney Ch'ng discusses the emerging role of robots in microsurgical reconstruction.  This episode discusses the following PRS Global Open article: “Feasibility and Current Applications of the Symani Surgical System: A Systematic Review” by Yu Jin Jeong, Amanda E. Yung, Daniel Steffens, Sophie Hogan, Jonathan R. Clark and Sydney Ch'ng. Read it for free on PRSGlobalOpen.com:  https://journals.lww.com/prsgo/fulltext/2025/07000/feasibility_and_current_applications_of_the_symani.28.aspx A/Prof Ch'ng is a plastic and reconstructive surgeon affiliated with Royal Prince Alfred Hospital, the University of Sydney and Chris O'Brien Lifehouse. Your host, Dr. Damian Marucci, is a board-certified plastic surgeon and Associate Professor of Plastic Surgery at the University of Sydney in Australia. #PRSGlobalOpen; #KeynotesPodcast; #PlasticSurgery; Plastic and Reconstructive Surgery- Global Open The views expressed by hosts and guests are their own and do not necessarily reflect the official policies or positions of ASPS.

Join Andrew and Rhen as they kick off an 4-part series that walks you through every stage of capital campaigns—from those critical first steps of the feasibility study to post-campaign transition back to your annual fund. Whether you're considering a campaign or just curious about the process, this series has everything you need to make informed decisions for your organization. Show Notes:Before you start asking for major gifts, there's one crucial step that can make or break your campaign: the feasibility study. Andrew and Rhen share the reasons why Petrus consistently recommends this research phase—and why skipping it could be a costly mistake. A feasibility study gives you concrete data to answer the big questions: Is now the right time? Can we realistically reach our goal? What do our donors think of our proposed project?  A feasibility study is an important investment in your campaign's success, and it helps organizations make smart, strategic capital campagin decisions from day one. If you'd like our free resource on feasilbity studies, please click HERE.  

Modern robotic picking is moving beyond neat rows and perfect lighting conditions. In this Automate 2025 conversation, Vlad and Dave sit down with Kevin Wu from Siemens to explore how Simatic Robot Pick AI Pro is tackling the messy reality of warehouses and factories. They discuss how the new edge architecture with the Simatic IPC BX 59 A and an NVIDIA GPU lifts pick rates to well over one thousand picks per hour, why multiple suction patterns matter for stability on large or flexible items, how camera agnostic support opens the door to new vision hardware, and why transparent objects are no longer a limitation in many applications.This episode also dives into digital thread and digital twin workflows using Siemens Process Simulate. These tools allow teams to test new products and layouts virtually before any hardware changes are made, helping reduce commissioning risk and shorten the path to production. The discussion highlights an on-booth demonstration that combines a robot with a secondary camera and a vision language model to identify products and read packaging details such as expiration dates. It is a clear example of how multimodal AI can complement traditional industrial vision systems.A major theme throughout this conversation is resilience. In real operations, products are rarely placed perfectly. Pallets shift, orientations vary, and lighting changes throughout the day. Traditional rules-based vision systems often struggle when small variances accumulate. Kevin explains how model-free 3D picking localizes unknown objects in clutter, selects stable suction patterns based on measured dimensions, and keeps production moving without forcing operators to maintain perfect alignment.For manufacturers in consumer packaged goods and medical devices, this is a meaningful advancement. It enables greater product variety and frequent SKU changes while maintaining engineering control. The difference is that the picking logic adapts to what the system sees rather than expecting the environment to remain static.We also talk about practical evaluation and proof of concept. Siemens runs application testing at its Berkeley, California lab where customers can send sample parts for quick feasibility checks. A short video of their parts being picked can provide the confidence needed to move forward with a pilot project while minimizing cost and risk. For quality inspection and defect detection, Siemens also offers an Inspector station capable of learning from as few as twenty samples to identify defects in real time.The discussion closes by looking at the future of digital manufacturing. Digital thread tools make it possible to simulate robots from multiple brands, test new configurations, and evaluate throughput virtually. Combined with edge AI and NVIDIA vision language technology, this creates faster experimentation cycles, improved reliability, and measurable gains in uptime and throughput.Kevin's key message is clear. Manufacturers do not need to replace existing automation to explore the benefits of AI. Start with one process, validate performance, and build from there.Timestamps 00:00 Welcome and why real-world picking matters 00:40 Introduction to Pick AI Pro and new throughput capabilities 01:30 Multi suction patterns for stable handling of large items 02:20 Camera agnostic approach and transparent object handling 03:30 Selecting components for high-temperature environments 04:15 Use cases in consumer packaged goods and medical applications 06:45 Digital twin and digital thread with Siemens Process Simulate 08:30 Feasibility testing and customer demos at the Siemens lab 10:30 Vision language model for product identification and labeling 12:10 Evaluating with real parts and rapid testing cycles 14:20 Siemens Inspector for defect detection and visual inspection 15:40 Key takeaways and future outlookReferences and Resources Mentioned Siemens Simatic Robot Pick AI Overview https://www.siemens.com/global/en/products/automation/topic-areas/tia/future-topics/simatic-robotics-ai.htmlSiemens Press Release on Simatic Robot Pick AI Pro https://press.siemens.com/global/en/pressrelease/siemens-presents-future-intralogistics-simatic-robot-pick-ai-pro-enables-machineSiemens Simatic IPC BX 59 A Industrial Edge Device with NVIDIA GPU https://www.automationworld.com/products/data/product/55287446/siemens-ag-siemens-simatic-ipc-bx-59a-industrial-edge-deviceSiemens IPC BX 59 A Operating Instructions https://support.industry.siemens.com/cs/attachments/109972660/ipcbx56a_and_ipcbx59a_operating_instructions_enUS_en-US.pdfUniversal Robots Example with Simatic Robot Pick AI https://support.industry.siemens.com/cs/document/109822788/simatic-robot-pick-ai-with-universal-robots-ur5Zivid Transparent Object Imaging Information https://www.zivid.com/zivid-omni-engine-transparency https://blog.zivid.com/zivid-omni-engineSiemens Digital Thread Overview and Tecnomatix Process Simulate https://www.sw.siemens.com/en-US/digital-thread/ https://plm.sw.siemens.com/en-US/tecnomatix/NVIDIA Vision Language Model Resources https://docs.nvidia.com/nim/vision-language-models/latest/introduction.html https://developer.nvidia.com/blog/vision-language-model-prompt-engineering-guide-for-image-and-video-understanding/Hosts Vlad Romanov is an electrical engineer and manufacturing consultant who leads Joltek and co-hosts the Manufacturing Hub Podcast. He focuses on practical strategies for SCADA, MES, and data-driven operations. Learn more at https://www.joltek.comYouTube Channel https://www.youtube.com/channel/UC6JpBeS_6JhUwfGF8RgLCIQDave Griffith is a manufacturing consultant and long-time co-host of Manufacturing Hub. He helps teams align operations, engineering, and leadership around the projects that move the needle in real production environments.Guest Kevin Wu from Siemens discusses Robot Pick AI Pro and related digital thread workflows across robotics and vision. Learn more about Siemens automation and software at https://www.siemens.com https://www.sw.siemens.com

In this KE Report Daily Editorial, we're joined by Brien Lundin, Editor of Gold Newsletter and host of the New Orleans Investment Conference (Nov. 2–5), to discuss the powerful rally across precious metals and the historic wave of financings sweeping through the junior mining sector. Key Discussion Highlights: Unprecedented capital inflows: Gold nearing $4,300/oz and silver topping $53/oz have triggered a flood of financings - many without warrants, rapidly upsized, and often the largest in company histories. Institutional money returns: Deep-pocketed generalist and hedge fund investors are pouring in, marking a seismic shift for the mining industry. What companies will do with the cash: With exploration budgets surging, Brien expects both inefficiency and discovery - some waste, but also new mines and mid-tier producers emerging. Valuation catch-up coming: Feasibility studies using $2,000–$2,500 gold are now badly outdated; developers could see massive re-ratings as markets recalibrate to current prices. Exploration strategy: How to approach pre-discovery and early-stage drill stories, and why management quality, technical depth, and early hints still matter most in a hot market. Stocks mentioned: Aftermath Silver (AAG.V / AAGFF), Blackrock Silver (BRC.V / BKRRF), Delta Resources (DLTA.V), Contango Ore (CTGO), Collective Mining (CNL.TO), Prospector Metals (PPP.V). Click here to learn more about the New Orleans Investment Conference on November 2-5.    ---------- For more market commentary & interview summaries, subscribe to our Substacks: https://kereport.substack.com/ https://excelsiorprosperity.substack.com/ Investment disclaimer: This content is for informational and educational purposes only and does not constitute investment advice, an offer, or a solicitation to buy or sell any security. Investing in equities and commodities involves risk, including the possible loss of principal. Do your own research and consult a licensed financial advisor before making any investment decisions. Guests and hosts may own shares in companies mentioned.

In this episode of All About Capital Campaigns, Amy Eisenstein and Andrea Kihlstedt, the co-founders of Capital Campaign Pro, invite listeners behind the scenes of a recent Campaign Conversations session: a live Q&A forum where nonprofit leaders ask their most pressing campaign questions.Four guests join to discuss real-life challenges many organizations face during their campaigns:Randy Whipple of the Working Ranch Cowboys Foundation shares his organization's plans to build a new headquarters and asks for advice on donor recognition ideas. Amy and Andrea explain why donor motivation comes from mission connection, not from names on plaques or bricks, and they describe how naming opportunities can be handled thoughtfully and effectively.Miranda Latchie from a church community seeks guidance on how to get started with a capital campaign. Amy and Andrea outline the first steps: defining a clear vision, estimating costs, assessing funding potential, and conducting a feasibility study. They also discuss the importance of planning early and engaging expert support before launching the campaign.Maria Harlow raises questions about using wealth screening tools to identify donor prospects. The conversation covers the benefits and limitations of data-driven insights, ethical considerations, and why curiosity and genuine donor relationships often reveal more than analytics alone. Amy and Andrea share how their team uses wealth screening as one part of a comprehensive strategy, not as a standalone solution.Amy McNeely, working in a busy development role at a homeless services organization, asks for advice on balancing campaign planning with day-to-day fundraising responsibilities. Andrea and Amy offer practical suggestions for prioritizing tasks, delegating effectively, and making the case for additional staffing or consulting support. They also stress the importance of campaign consultants in training staff, keeping leadership aligned, and preventing burnout.Throughout the episode, Amy and Andrea provide candid, experience-based guidance drawn from decades of supporting campaigns of every size. Their discussion emphasizes planning with intention, engaging key donors personally, and setting organizations up for long-term fundraising success.Whether you're preparing for your first campaign, refining your donor engagement strategies, or juggling multiple fundraising priorities, this episode offers insights that will help you move forward with clarity and confidence.Key Topics Covered:How to approach donor recognition meaningfullyEarly planning and feasibility assessment for campaignsUnderstanding the role and limits of wealth screeningManaging time, priorities, and staff resources during a campaignThe value of campaign consulting and leadership educationTo ensure your campaign ends in a celebration, download our free Capital Campaign Step-by-Step Guide & Checklist. This intuitive guide breaks down each step of your campaign, and the timeline allows you to visualize your whole campaign, from start to finish!

Feasibility of a Smartphone App with Mindfulness Training for Adolescent Smoking Cessation: Craving to Quit (C2Q)-TeenIn this episode, Dr. Jud highlights a groundbreaking pilot study that examines the feasibility of a mindfulness-based smoking cessation app tailored for teenagers. Based on the paper Feasibility of a Smartphone App with Mindfulness Training for Adolescent Smoking Cessation: Craving to Quit (C2Q)-Teen by Lori Pbert et al., the episode delves into how mindfulness helps teens recognize and manage cravings. Despite similar abstinence rates across the app, a non-mindfulness app, and written materials, the Craving to Quit app stood out for reducing cigarette consumption in adolescents who continued to smoke. Dr. Jud explores the implications of these findings and the potential of app-based mindfulness interventions to provide accessible and impactful smoking cessation tools for adolescents.Reference:Pbert, L., Druker, S., Crawford, S., Frisard, C., Trivedi, M., Osganian, S. K., & Brewer, J. Feasibility of a Smartphone App with Mindfulness Training for Adolescent Smoking Cessation: Craving to Quit (C2Q)-Teen. Mindfulness. 2019. DOI: 10.1007/s12671-019-01273-wLet's connect on Instagram

Could a simple supplement that bodybuilders use to build muscle actually help fight Alzheimer's disease? Dr. Matthew Taylor from the University of Kansas reveals surprising results from her groundbreaking clinical trial testing high-dose creatine in Alzheimer's patientsIn this episode, Dr. Matthew Taylor discusses his pioneering research on creatine supplementation for Alzheimer's disease, addressing a critical gap in brain energy metabolism that worsens with aging and becomes severely impaired in dementia. His 8-week clinical trial gave 20 Alzheimer's patients 20 grams of creatine daily - a bodybuilder's loading dose - and found remarkable improvements in memory, executive function, and even unexpected gains in reading comprehension. Using advanced MRI spectroscopy, his team confirmed that creatine actually reaches the brain, increasing levels by 11%. Beyond cognitive benefits, participants also showed significant improvements in hand grip strength and muscle mass. Dr. Taylor explains how brain energy metabolism creates a vicious cycle in Alzheimer's, explores whether creatine could prevent dementia in healthy aging, and reveals his plans for combining creatine with ketogenic diet approaches. This conversation offers hope for a simple, accessible intervention that could help millions facing cognitive decline.

Creatine is everywhere right now. While the supplement has been popular for years among gym rats, the benefits of taking creatine now far surpass gaining muscle strength—and especially for women. What are those benefits? How much creatine should you be taking? When should you take it? And will it make you gain weight? We answer all of these questions in today's episode.   Some of the studies mentioned in the episode: Single dose creatine improves cognitive performance and induces changes in cerebral high energy phosphates during sleep deprivation Creatine monohydrate pilot in Alzheimer's: Feasibility, brain creatine, and cognition Creatine Supplementation Combined with Exercise in the Prevention of Type 2 Diabetes: Effects on Insulin Resistance and Sarcopenia Creatine Supplementation in Women's Health: A Lifespan Perspective Thank you for listening to The Happy Eating Podcast. Tune in weekly on Thursdays for new episodes! For even more Happy Eating, head to our website!  https://www.happyeatingpodcast.com Learn More About Our Hosts:  Carolyn Williams PhD, RD: Instagram: https://www.instagram.com/realfoodreallife_rd/ Website: https://www.carolynwilliamsrd.com Facebook: https://www.facebook.com/RealFoodRealLifeRD/ Brierley Horton, MS, RD Instagram: https://www.instagram.com/brierleyhorton/ Got a question or comment for the pod? Please shoot us a message!  happyeatingpodcast@gmail.com Produced by Lester Nuby OE Productions

Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Ideal Navitor Implant Depth for Redo-TAVR Feasibility and Coronary Access: A CT Simulation Study.

Interview with Joseph Ovsenek, President & CEO of P2 Gold Inc.Our previous interview: https://www.cruxinvestor.com/posts/p2-gold-inc-tsxvpgld-35moz-project-advances-on-metallurgical-breakthrough-7826Recording date: 11th September 2025P2 Gold presents one of the most compelling value propositions in the current gold mining sector, offering investors exposure to a high-quality Nevada development project with exceptional economics and experienced management execution capabilities. The company's Gabbs project demonstrates robust financial metrics that appear significantly disconnected from its current market valuation, creating a substantial opportunity for value recognition and appreciation.The project's preliminary assessment reveals impressive economics with a 62% internal rate of return and $700 million net present value at a 10% discount rate when current metal prices are applied. These figures stand in stark contrast to P2 Gold's market capitalization of just $25 million, suggesting a potential 28-fold upside if the market recognizes the project's intrinsic value. The 3.5 million ounce gold equivalent resource base provides substantial scale, while the Nevada location offers regulatory advantages and established mining infrastructure that reduce development risks.Recent metallurgical breakthroughs represent a significant catalyst for enhanced project economics and accelerated development timelines. Phase 3 metallurgical results demonstrated remarkable improvements, with gold recovery rates increasing from 78% to 85% and copper recovery jumping from 54% to 67%. Perhaps more importantly, extraction kinetics improved dramatically, with 98% of gold now recoverable in 58 days compared to the previous 145-day timeline. This improvement could reduce capital expenditure requirements and project footprint size when advancing to feasibility study.Management credibility provides crucial execution confidence for investors evaluating development-stage mining opportunities. CEO Joseph Ovsenek and Chief Exploration Officer Ken McNaughton previously collaborated at Pretium Resources, successfully advancing the Bruce Jack project from discovery to production in under eight years. Their proven track record demonstrates capability in navigating complex development processes including resource expansion, permitting, financing, and construction management. The team's philosophy of setting aggressive targets and maintaining development momentum has translated into P2 Gold's ambitious 2028 production timeline.The company's strategic approach to development acceleration includes skipping pre-feasibility study and advancing directly to feasibility based on extensive historical data and the project's straightforward heap leach processing characteristics. This decision could compress typical development timelines while leveraging Nevada's established regulatory framework and heap leach infrastructure. The addition of SART plant technology for gold and copper oxide recovery represents the primary technical innovation required, with numerous similar facilities already operating successfully.Near-term catalysts provide multiple opportunities for market recognition and potential re-rating over the next 12 months. Expansion and infill drilling beginning in mid-to-late October should generate results over six months, potentially expanding the resource base and providing additional geological confidence. Key regulatory milestones including water permitting and mining plan of operation filing within four to five months will demonstrate tangible progress toward production.P2 Gold's current financing round targeting C$6 million with potential expansion based on strong investor interest demonstrates improving market sentiment and capital access. The relatively modest funding requirements reflect the project's efficient development pathway and extensive historical database, allowing the company to maintain aggressive advancement while preserving shareholder dilution.At current gold prices exceeding $3,600 per ounce, P2 Gold offers compelling leverage to continued metal price appreciation while providing downside protection through robust project economics and experienced management execution capabilities.Learn more: https://cruxinvestor.comSign up for Crux Investor: https://cruxinvestor.com

Ductal carcinoma in situ (DCIS) represents a clinical crossroads in breast surgery—balancing the risks of over-treatment with the need to prevent invasive cancer. With new data from active monitoring trials, the pressure is on for surgeons to personalize care. Tune in to this essential episode to stay ahead of the curve on DCIS management and to hear expert insights from two leading breast surgical oncologists. Hosts: - Rashmi Kumar, MD, PhD Resident, University of Michigan General Surgery Residency Program Twitter/X: @RashmiJKumar - Melissa Pilewskie, MD Attending Breast Surgical Oncologist, Co-Director of the Weiser Family Center for Breast Cancer, Michigan Medicine Twitter/X: @MPilewskie -  Stephanie Downs-Canner, MD Attending Breast Surgical Oncologist & Physician-Scientist, Memorial Sloan Kettering Cancer Center, Program Director of the Breast Surgical Oncology Fellowship Training Program Twitter/X: @SDownsCanner Learning Objectives: - Define DCIS and explain its significance as a precursor to invasive breast cancer. - Discuss challenges in diagnosing and risk-stratifying DCIS. - Review current standards for surgical and adjuvant management of DCIS. - Understand the implications of new research, including the COMET trial, for low-risk DCIS. - Evaluate patient-centered strategies for managing DCIS and preventing over-treatment. References: - Worni M, Akushevich I, Greenup R, et al. Trends in Treatment Patterns and Outcomes for Ductal Carcinoma In Situ. J Natl Cancer Inst. 2015;107(12):djv263. PubMed - Francis A, Thomas J, Fallowfield L, et al. Addressing overtreatment of screen detected DCIS; the LORIS trial. Eur J Cancer. 2015 Jan;51(16):2296-303. PubMed - Elshof LE, Tryfonidis K, Slaets L, et al. Feasibility of a non-surgical management strategy for low-grade DCIS: The LORD study. Eur J Cancer. 2015;51(12):1497–1510. PubMed - Toss MS, et al. Ductal carcinoma in situ (DCIS): current management and future directions. Cancer Treat Rev. 2020;90:102091. PubMed - Comparative Effectiveness of Surgery versus Active Monitoring for Low-Risk DCIS (COMET) Trial Results. Early COMET Results: King TA, et al. Surgical excision versus active monitoring for low-risk ductal carcinoma in situ (DCIS): 2-year results of the COMET randomized trial. J Clin Oncol. 2024; e2400110. PubMed Please visit https://behindtheknife.org to access other high-yield surgical education podcasts, videos and more.   If you liked this episode, check out our recent episodes here: https://behindtheknife.org/listen Behind the Knife Premium: General Surgery Oral Board Review Course: https://behindtheknife.org/premium/general-surgery-oral-board-review Trauma Surgery Video Atlas: https://behindtheknife.org/premium/trauma-surgery-video-atlas Dominate Surgery: A High-Yield Guide to Your Surgery Clerkship: https://behindtheknife.org/premium/dominate-surgery-a-high-yield-guide-to-your-surgery-clerkship Dominate Surgery for APPs: A High-Yield Guide to Your Surgery Rotation: https://behindtheknife.org/premium/dominate-surgery-for-apps-a-high-yield-guide-to-your-surgery-rotation Vascular Surgery Oral Board Review Course: https://behindtheknife.org/premium/vascular-surgery-oral-board-audio-review Colorectal Surgery Oral Board Review Course: https://behindtheknife.org/premium/colorectal-surgery-oral-board-audio-review Surgical Oncology Oral Board Review Course: https://behindtheknife.org/premium/surgical-oncology-oral-board-audio-review Cardiothoracic Oral Board Review Course: https://behindtheknife.org/premium/cardiothoracic-surgery-oral-board-audio-review Download our App: Apple App Store: https://apps.apple.com/us/app/behind-the-knife/id1672420049 Android/Google Play: https://play.google.com/store/apps/details?id=com.btk.app&hl=en_US

Today my guests are Dr Alexander Perez and Dr Michael Topf. What we discuss with Dr Perez and Dr Topf: The challenge of documenting surgical specimens with traditional text and photos How 3D scanning improves accuracy and communication in pathology Integration into the gross room workflow with minimal time impact Clinical applications: tumor boards, surgical navigation, and radiation therapy planning Educational value: training residents, 3D printing, and virtual/augmented reality Patient-facing benefits, including education and visualization Cost accessibility: high-quality scanners for around $2,000 Collaboration and sharing of protocols to encourage wider adoption Future outlook: from long-term digital storage to medicolegal uses and beyond Links for this episode: The Path to PathA Pathologists' Assistant Shadowing Network Health Podcast Network  LabVine Learning Dress A Med scrubs Digital Pathology Club   Ex vivo 3D scanning and specimen mapping in anatomic pathology Augmented-Reality Surgery to Guide Head and Neck Cancer Re-resection: A Feasibility and Accuracy Study Visual pathology reports for improved collaboration at multidisciplinary head and neck tumor board   People of Pathology Podcast: Twitter Instagram  

An economist has raised concerns over NZ First's proposed reform for KiwiSaver contributions - and claimed they're not feasible. NZ First recently promised to make it compulsory and increase contributions from employers and workers to 10 percent - offset by a tax cut. Simplicity chief economist Shamubeel Eaqub says he approves of the idea of a compulsory scheme, but warns we can't afford a tax-funded one. LISTEN ABOVESee omnystudio.com/listener for privacy information.

Summary The podcast discusses a recent pilot study on the effects of passive blood flow restriction (BFR) exercise on muscle atrophy following total knee replacement surgery. The conversation highlights the significant muscle mass loss that occurs post-surgery and the potential of BFR to mitigate this loss. The study design, methodology, and key findings are explored, emphasizing the importance of early intervention and the feasibility of implementing BFR in clinical settings. The hosts discuss the implications of the findings for rehabilitation practices and future research directions. Chapters 00:00 Introduction and Overview of the Study 03:15 Understanding Muscle Atrophy Post-Surgery 07:12 The Role of Blood Flow Restriction in Rehabilitation 12:53 Study Design and Methodology 15:35 Key Findings and Implications of the Study 20:54 Exploring Remote Ischemic Preconditioning 22:42 Functional Outcomes and Clinical Significance 25:11 Grip Strength Recovery and Clinical Changes 27:01 Safety and Feasibility of BFR 28:42 Implementing BFR in Clinical Practice 30:25 Prehabilitation and Postoperative Care 32:47 Expanding Applications of BFR in Acute Care Podcast Intro Attribution Song: Legendary Music by: CreatorMix.com Video: https://youtu.be/_oaZzkn0bW4 Podcast Outro Attribution Song: Smoke Rising Music by: CreatorMix.com Video: https://youtu.be/_oaZzkn0bW4

Summary In this episode of Develop This!, Dennis Fraise and Rick Kiernan with Convergent Nonprofit Solutions discuss the evolving landscape of funding for economic development organizations. They explore the shift from traditional funding methods to a focus on workforce development, housing, placemaking, and childcare. Rick shares insights from his extensive experience in fundraising and highlights the importance of feasibility studies in understanding community needs. The conversation emphasizes the necessity of having a well-structured plan to attract funding and support for various initiatives that enhance community appeal and address workforce challenges. Takeaways Economic development funding has evolved significantly over the years. Workforce development is now the primary focus for economic development organizations. Feasibility studies provide critical insights into community needs. Housing shortages are a major barrier to attracting talent. Placemaking is increasingly important for community attractiveness. Childcare availability directly impacts workforce participation. Community engagement is essential for successful fundraising campaigns. Economic development organizations must adapt to changing priorities. Collaboration with local stakeholders enhances fundraising efforts. A well-defined plan is crucial for securing funding and support.

Properties for Sale on the North Side?  We want to buy them. Email: StraightUpChicagoInvestor@gmail.com Have a vacancy? We can place your next tenant and give you back 30-40 hours of your time. Learn more: GCRealtyInc.com/tenant-placement Has Property Mgmt become an opportunity cost for you? Let us lower your risk and give you your time back to grow. Learn more: GCRealtyinc.com ============= Fernando Angelucci returns to the podcast to explain how he has rapidly grown his self storage business and the drivers behind increasing self storage demand! Fernando explains his marketing strategy to optimize deal flow despite the low inventory environment. He delves deep into the underwriting and feasibility studies performed on self storage investments to maximize returns. Fernando provides the 101 on various financing options and repositioning strategies for self storage investments. He closes with a motivating 5-year outlook including a detailed plan to reach financial independence! If you enjoy today's episode, please leave us a review and share with someone who may also find value in this content! ============= Connect with Mark and Tom: StraightUpChicagoInvestor.com Email the Show: StraightUpChicagoInvestor@gmail.com Guests: Fernando Angelucci, Self Storage Syndicated Equities Link: Fernando's Instagram Link: SUCI Ep 86 - Fernando Angelucci Link: Vagabonding (Book Recommendation) Link: SUCI Ep 392 - Cost Seg Kev Guest Questions 01:49 Housing Provider Tip - Be sure to perform maintenance on AC units after a long summer! 03:25 Intro to our guest, Fernando Angelucci! 06:41 Growing a portfolio in a low inventory market! 12:10 Feasibility studies on self storage projects. 16:44 Building a self storage investment team! 21:56 Financing self storage deals. 37:33 Repositioning a self storage investment. 47:57 Obtaining special use permits. 52:01 Ideal self storage projects! 55:23 Fernando's 5-year outlook. 60:26 What is your competitive advantage? 62:55 One piece of advice for new investors. 63:32 What do you do for fun? 64:14 Good book, podcast, or self development activity that you would recommend?  64:48 Local Network Recommendation?  65:53 How can the listeners learn more about you and provide value to you? ----------------- Production House: Flint Stone Media Copyright of Straight Up Chicago Investor 2025.

This webinar will look at stages of the RI/FS, from RMM through the FS.  Presentations will discuss how to create risk scenarios for evaluation using the Risk Management Methodology (RMM) and explain how that can influence the development of remedial alternatives by considering both contamination and land use.  The presentations will look at an example site and at a case study.  We will also discuss the use of "FS alternatives panels" to facilitate the development of remedial alternatives and attempt to get buy-in from various members of the project team. To view this archive online or download the slides associated with this seminar, please visit http://www.clu-in.org/conf/tio/m2s2fy24-1_082825/

This webinar will look at stages of the RI/FS, from RMM through the FS.  Presentations will discuss how to create risk scenarios for evaluation using the Risk Management Methodology (RMM) and explain how that can influence the development of remedial alternatives by considering both contamination and land use.  The presentations will look at an example site and at a case study.  We will also discuss the use of "FS alternatives panels" to facilitate the development of remedial alternatives and attempt to get buy-in from various members of the project team. To view this archive online or download the slides associated with this seminar, please visit http://www.clu-in.org/conf/tio/m2s2fy24-1_082825/

On Episode #178 of the PricePlow Podcast, Ben and guest co-host Joey Savage take listeners inside Veritacor Manufacturing in Luling, Texas, for an exclusive facility tour and in-depth conversation with founders Frank Santos and Derek Curtiss. This episode provides a rare behind-the-scenes look at what it takes to build and operate an NSF-certified, GMP-compliant supplement manufacturing facility from the ground up. From their humble beginnings with a single encapsulator to their current 32,500 square foot operation, Frank and Derek share the meticulous processes, quality control systems, and attention to detail that set Veritacor apart in the competitive contract manufacturing landscape. The discussion dives deep into the technical aspects of supplement production, from vendor qualification and raw material testing to the critical differences between ribbon and paddle blenders, while also exploring their ambitious growth plans to reach 200,000 square feet of manufacturing space. This discussion and forthcoming facility tour showcases not just Veritacor's impressive capabilities in powder blending, encapsulation, and fulfillment, but also their commitment to elevating industry standards through rigorous third-party auditing, comprehensive SOPs, and a culture of continuous improvement. Whether you're a brand owner looking for a manufacturing partner or simply interested in understanding how supplements are made at the highest quality levels, this episode delivers unprecedented insights into modern nutraceutical manufacturing. Subscribe to the PricePlow Podcast to hear more conversations with industry innovators and manufacturers shaping the future of supplements! https://blog.priceplow.com/podcast/veritacor-supplement-manufacturing-178 Video: Inside Veritacor Manufacturing Facility Tour https://www.youtube.com/watch?v=An7FhkG9bZE Detailed Show Notes: GMP Excellence and Manufacturing Innovation (0:00) – Introduction: A Dream Realized in Manufacturing (1:30) – Derek's Journey: From Indian Botanicals to COO (3:30) – Building from Scratch: The Veritacor Origin Story (6:00) – The Path to NSF Certification: Setting the Standard (8:15) – Customer Onboarding: From Formula to Feasibility (10:15) – Vendor Qualification: The Foundation of Quality (12:15) – The Critical Weighing and Blending Process (14:30) – Blending Technology Deep Dive: Ribbon vs. Paddle vs. Bin (17:15) – Quality Control: Multi-Point Testing and Validation (19:45) – Manufacturing Capabilities and Core Specializations (22:30) – Core Culture: Demonstrating Capabilities Through House Brands (25:00) – Facility Evolution: Creative Solutions and Strategic Growth (28:00) – NSF Audit Stories: Learning from Scrutiny (31:00) – Stability Testing and Shelf Life Determination (34:00) – Third-Party Logistics: Complete Supply Chain Solutions (36:30) – NetSuite Implementation: Digital Transformation (39:00) – Community Impact: Building Local Talent (42:00) – The Business of Manufacturing: Costs and Timelines (45:00) – Blender Selection Strategy: The Right Tool for Each Job (48:00) – Expansion Vision: The Path to 200,000 Square Feet (51:00) – Product Categories and Sp... Read more on the PricePlow Blog

With the Fed's latest decision to hold rates, one thing became clear- tariffs are already affecting the real estate market.This week on Not Your Average Insights, JWB Co-Founder Gregg Cohen and host Pablo Gonzalez break down the role tariffs play in the Fed's decision, and other headlines to consider.We'll talk about:•⁠  ⁠Why the Fed's pause on rate hikes is tied to tariffs•⁠  ⁠What Florida's governor is proposing that has everyone looking at Florida real estate•⁠  ⁠Where the “10 Slowest Housing Markets” were reported to be, and which ones we agree with•⁠  ⁠and more!Listen NOW!Chapters:00:00 Introduction to Not Your Average Insights01:24 Welcome Back to the Show04:13 Discussion on Fed's Interest Rate Decision06:05 Impact of Tariffs on Housing Market13:05 Jobs Report and Fed's Future Decisions19:34 Ron DeSantis' Proposal to Eliminate Property Taxes25:06 Debating Property Tax Elimination25:44 Governor's Perspective on Government Spending26:19 Impact of Sales Tax on Different Income Groups26:54 Feasibility of Sales Tax Increase28:57 Potential Property Tax Rebate29:14 Revisions to Government Job Numbers32:52 Interest Rates and Mortgage Market36:59 JWB Cares Fundraising Update38:25 Analyzing Housing Market Data42:54 Long-Term Investment Strategies49:40 Conclusion and Upcoming EventsStay connected to us! Join our real estate investor community LIVE: https://jwbrealestatecapital.com/nyai/Schedule a Turnkey strategy call: https://jwbrealestatecapital.com/turnkey/ *Get social with us:*Subscribe to our channel  @notyouraverageinvestor  Subscribe to  @JWBRealEstateCompanies  

Gene Marks sits down with Senior Benefits Manager at Paychex, Tami Tillery, to answer the top questions from a recent webinar on the evolving landscape of employee benefits. They discuss how businesses, particularly in rural and underserved areas, can creatively manage healthcare costs while providing robust employee benefits. A major focus is on leveraging technology and innovative solutions such as telehealth, mobile health units, and AI to enhance employee well-being in a cost-effective manner. Whether you're a small business or a large enterprise, understanding how to effectively manage benefits and costs is crucial. Watch the on-demand webinar, Sustainable Benefit Strategies for Every Business Stage, at: https://bit.ly/4mt98uO Have a question for upcoming episodes or a topic you want covered? Let us know: https://payx.me/thrivetopics Topics include: 00:00: Episode preview 00:41: Overview of the "Sustainable Benefit Strategies" webinar 01:28: Rising healthcare costs insights 02:27: Strategies for rural employers 05:19: Healthcare costs and age groups 07:10: How to pick insurance plan designs from different carriers 10:21: Feasibility and advice for small businesses to offer group insurance 14:33: Getting the right benefits support 20:25: Strategies for rural employers balancing costs and quality 23:50: Predictions on future benefits trends 30:17: Wrap up and thank you DISCLAIMER: The information presented in this podcast, and that is further provided by the presenter, should not be considered legal or accounting advice, and should not substitute for legal, accounting, or other professional advice in which the facts and circumstances may warrant. We encourage you to consult legal counsel as it pertains to your own unique situation(s) and/or with any specific legal questions you may have.

In this episode of THE MENTORS RADIO, Host Tom Loarie talks with Mai Nguyen, PhD, the remarkable 36-year-old neuroscientist who is the co-founder and CEO of OptoCeutics and the inventor of EVY LIGHT®, a breakthrough light-based therapy aimed at slowing the progression of Alzheimer's and other memory disorders. Her journey is anything but ordinary. Born in Vietnam, raised in California as the youngest of nine children in a struggling family, she spent her childhood at a local Flea Market and then went on to earn a PhD in neuroscience. But it was a "chance" conversation with a Danish professor that changed her life, and quite likely the lives of millions who will benefit from her decision. In this episode, you'll explore the science behind Dr. Mai Nguyen's light therapy innovation, her deeply personal and unlikely entrepreneurial journey and the powerful values that have guided her. This is a conversation about courage, healing and what it means to be a leader with heart and grit.  Listen to THE MENTORS RADIO podcast anywhere, any time, on any platform, including Spotify and Apple, just click here! Of course, we are always grateful for your 5-star review on Spotify and Apple podcasts, which helps us reach even more people!! SHOW NOTES: MAI NGUYEN, Ph.D.: BIO: https://optoceutics.com/about/about-mai-nguyen/ COMPANY: https://optoceutics.com/ ARTICLES: Mai Nguyen of OptoCeutics: Five Things I Wish Someone Told Me Before I Became a CEO Can flashing lights stall Alzheimer's? What the science shows Safety, Feasibility, and Potential Clinical Efficacy of 40 Hz Invisible Spectral Flicker versus Placebo in Patients with Mild-to-Moderate Alzheimer's Disease: A Randomized, Placebo-Controlled, Double-Blinded, Pilot Study

Political theorist Annabel Brett of Cambridge University explores how the concept of “moral possibility” shapes law, politics, and public obligation. She explains that laws must be realistic for people to follow—what is morally possible varies by individual, culture, time, and circumstance. Drawing on early modern Catholic legal theory, Brett discusses how extreme demands (like enduring war or plague) may justify higher expectations, but only temporarily. She examines how colonial Spanish officials misused this framework to justify forced labor in Peru, wrongly claiming it aligned with indigenous customs. Brett contrasts this with more democratic approaches to law, like Domingo de Soto's defense of beggars' rights, which take individuals' real conditions seriously. Ultimately, she shows how moral possibility is deeply tied to time, virtue, and justice. Commentary is provided by David Dyzenhaus of the University of Toronto. Series: "UC Berkeley Graduate Lectures" [Public Affairs] [Humanities] [Show ID: 40430]

Most people assume creatine is only for bodybuilders, but new research is challenging that belief. In this episode, Chalene dives into the surprising, science-backed benefits of creatine for women, particularly those in midlife. From brain health and bone density to hormonal support and cognitive function, this supplement might be one of the most underrated tools for aging powerfully. She also busts common myths like weight gain and bloating, and explains why some experts are calling it “the magnesium of 2025.” If you're curious about how to take it, which brands are trustworthy, and how to avoid getting scammed, this episode lays it all out. Watch this episode on YouTube this Sunday!!  https://www.youtube.com/@chalenejohnson/videos  

La Dra. Ana Valeria Aguirre, investigadora del Hospital Nacional de Rehabilitación MedStar, entrevista a la Dra. Carter Denny, Neuróloga Vascular e investigadora clínica de MedStar y la Universidad de Georgetown, sobre el artículo "Seguridad, viabilidad y eficacia de la estimulación transcutánea del nervio tibial en la vejiga neurogénica con lesión aguda de la médula espinal: un ensayo piloto aleatorizado de control". En este episodio las Doctoras analizaran este tipo de intervención, que consiste en la estimulación del nervio tibial, utilizada en otras poblaciones, y cómo se utiliza actualmente para mejorar la función vesical en personas con vejiga neurogénica. Para acceder a este artículo de la revista, haga clic aquí:  https://www.sciencedirect.com/science/article/abs/pii/S1094715921019917?via%3Dihub https://bladderbuzzpodcast.buzzsprout.com/1290071/episodes/10293954-journal-article-safety-feasibility-and-efficacy-of-transcaternity-tibial-nerve-stimulation-in-acute-spinal-cord-injury-neurogenic-bladder Safety, Feasibility, and Efficacy of Transcutaneous Tibial Nerve Stimulation in Acute Spinal Cord Injury Neurogenic Bladder: A Randomized Control Pilot Trial - ScienceDirect

Dr. Linda Chu reviews recent articles in the Generative AI Collection, covering clinical history extraction, case interpretation with vision language models, and report proofreading.   The articles covered in the podcast are: Leveraging Large Language Models to Generate Clinical Histories for Oncologic Imaging Requisitions | Radiology   Assessing Completeness of Clinical Histories Accompanying Imaging Orders Using Adapted Open-Source and Closed-Source Large Language Models | Radiology   Impact of Multimodal Prompt Elements on Diagnostic Performance of GPT-4V in Challenging Brain MRI Cases | Radiology   Generative Large Language Models Trained for Detecting Errors in Radiology Reports | Radiology   Large-Scale Validation of the Feasibility of GPT-4 as a Proofreading Tool for Head CT Reports | Radiology

AI for Site Feasibility: Streamlining Zoning, Codes, and Permits for ArchitectsIn this episode of the podcast, Gayathri (G3) Venkataraman, founder and CEO of Dota.ai, shares her inspiring journey from leading product teams at Microsoft and DocuSign to launching her own startup focused on transforming site feasibility and permitting in the construction industry. Frustrated by outdated, fragmented data systems, G3 created Dota.ai to consolidate information on land use, zoning, and building codes into one streamlined, accessible platform. She explains how AI can dramatically speed up the pre-development process, allowing architects and developers to make smarter, faster decisions.G3 dives into the unique challenges of integrating advanced technology into the traditionally conservative construction sector and discusses the future potential of AI to reshape urban planning and civic tech. She also reflects on her mission to empower real estate and design professionals, ultimately driving both operational efficiency and community impact. As a nonprofit board chair, G3 believes deeply in using technology for the greater good and shares insights on balancing innovation with societal responsibility.Throughout the conversation, she offers practical advice to small firm architects on embracing change and cultivating a mindset of continuous improvement in their practices.This week at EntreArchitect Podcast, AI for Site Feasibility: Streamlining Zoning, Codes, and Permits for Architects with Gayathri (G3) Venkataraman.Connect with G3 online at Dota.ai or find her on LinkedIn and Instagram.Please Visit Our Platform SponsorsArcatemy is Arcat's Continuing Education Program. Listen to Arcat's Detailed podcast and earn HSW credits. As a trusted provider, Arcat ensures you earn AIA CE credits while advancing your expertise and career in architecture. Learn more at Arcat.com/continuing-education.Visit our Platform Sponsors today and thank them for supporting YOU... The EntreArchitect Community of small firm architects.

Creatine for Alzheimer's — let's separate the hype from the hope. A new study has caused a stir in June 2025, but lead researcher Matthew K. Taylor told us: “ I don't think I can recommend it to a patient that this is going to ultimately have some sort of cognitive influence.” We speak to Dr. Taylor and Dr. Russell Swerdlow in this episode, discussing: • Role of creatine in your brain, and why it matters for energy metabolism • What the 2025 study found (and why it wasn't designed to prove effectiveness) • How scientific nuance gets lost in supplement hype • Why even promising early data must be handled with care • The vital difference between hype and hope Dr. Russell Swerdlow, MD is Director of the University of Kansas Alzheimer's Disease Research Center. Dr. Matthew Taylor, PhD, RD is Associate Professor of Dietetics & Nutrition at the University of Kansas Medical Center. This is... Your Brain On Creatine. SUPPORTED BY: NEURO World. Help your brain thrive, now and into the future: https://neuro.world/  ‘Your Brain On' is hosted by neurologists, scientists, and public health advocates Ayesha and Dean Sherzai.  ‘Your Brain On... Creatine' • SEASON 5 • EPISODE 8 LINKS  Dr. Taylor at the University of Kansas: https://www.kumc.edu/mtaylor3.html Dr. Swerdlow at the University of Kansas: https://www.kumc.edu/rswerdlow.html REFERENCES 1. Smith AN, Choi IY, Lee P, Sullivan DK, Burns JM, Swerdlow RH, Kelly E, Taylor MK. Creatine monohydrate pilot in Alzheimer's: Feasibility, brain creatine, and cognition. Alzheimer's & Dementia: Translational Research & Clinical Interventions. 2025 Apr;11(2):e70101. 2. Taylor MK, Burns JM, Choi IY, et al. Protocol for a single-arm, pilot trial of creatine monohydrate supplementation in patients with Alzheimer's disease. Pilot Feasibility Study. 2024;10(1):42.  3. Habeck C, Risacher S, Lee GJ, et al. Relationship between baseline brain metabolism measured using [18 F]FDG PET and memory and executive function in prodromal and early Alzheimer's disease. Brain Imaging Behav. 2012;6(4):568-83.  4. Kreider RB, Kalman DS, Antonio J, et al. International Society of Sports. Nutrition position stand: safety and efficacy of creatine supplementation in exercise, sport, and medicine. J Int Soc Sports Nutr. 2017;14:18.