Podcasts about Feasibility

Join our Patreon and get access to monthly bonus episodes and more nutriton content!Can fasting really slow aging? Does calorie restriction work for humans, or just for mice and yeast? And how much protein do you actually need to age well? This week on Your Diet Sucks, we break down the evidence behind the most talked-about interventions in the longevity space, what holds up under scrutiny, what doesn't, and why you might not need a supplement stack to live longer, and enjoy life. We dig into:The actual science on calorie restriction, fasting, and supplements—and where the evidence stopsWhat inflammation, oxidative stress, and telomeres have to do with how we ageThe best-researched dietary patterns for living longer (hint: it's not sexy, but it might include red wine)Why protein becomes more important as we ageThe difference between lifespan and healthspan, and why quality of life needs to be part of the conversation

What makes a clinical trial site successful when managing complex transplant studies? In this episode of “Moving Medicine Forward,” host Jeremy Schrand is joined by Shawna Bredek, a 20+ year veteran in clinical trial operations, to explore how feasibility assessments shape the future of life-saving research. Shawna shares how her team evaluates sites, navigates post-COVID challenges, tackles regulatory hurdles, and builds lasting relationships that help bring rare disease treatments and transplant innovations to life. Whether you're working in clinical research or simply curious about medical breakthroughs, this episode offers a compelling look at the strategy behind meaningful science.  Show Notes: 00:36 Meet Shawna Bredeck, VP Global Site Activation & Clinical Document Management at CTI 00:52 Feasibility in the context of a clinical trial 01:18 Why choosing the right site and Private Investigator is critical 02:12 Post-COVID challenges: site fatigue, turnover, and timelines 03:34 Sponsors' expectations vs. site realities 04:03 Asking tough feasibility questions upfront 05:17 Transplant-specific logistics: 24/7 coverage and site readiness 05:54 Navigating regulatory red tape across countries 07:28 How regulatory delays can stall important trials 08:12 Global differences: why it's easier to start in Brazil than the US 08:54 Engaging rare disease sites through relationships and reputation 09:56 Partnering with advocacy groups for trial success 10:58 Shawna's proudest career moment: a major transplant drug approval 12:21 The human side of transplant research 12:50 The shared mission of patients, sponsors, sites, and scientists 13:02 Final thoughts and how to connect with CTI 

Here's how I can help you: Courses https://www.dickersoninternational.com/coursesMentorshiphttps://www.dickersoninternational.com/mentorshipConnect with me here: Facebook: https://www.facebook.com/pg/thegregdickersonInstagram: https://www.instagram.com/thegregdickersonLinkedIn: https://www.linkedin.com/in/agregdickersonTwitter: https://twitter.com/agregdickersonYouTube: https://www.youtube.com/user/agregdickerson/?sub_confirmation=1Podcast: https://www.dickersoninternational.com/podcast#realestatedevelopment #realestateinvesting #realestate Greg is a serial entrepreneur, real estate developer, coach and mentor to high level investors around the world. He has bought, developed and sold over $250 million in real estate, built and renovated hundreds of custom homes and commercial buildings, developed residential and mixed-use subdivisions and started 12 different companies from the ground up. Greg currently mentors some of the top entrepreneurs, real estate investors and real estate developers in the country helping them grow and scale their business, raise more capital and do bigger deals. Greg's current clients have over $2 billion in AUM and deals in the process.Greg is an expert on the topics of entrepreneurship, leadership and real estate and is regularly interviewed on some of the top real estate investing and business podcasts today.Greg served in the United States Navy right out of high school and has always been a leader in the community as well as supporting, advising and serving on the boards of several churches, ministries and non-profit organizations. This channel is all about Entrepreneurship, Real Estate Investing and Real Estate Development*Nothing in this video or podcast is meant to be construed as legal or investment advice, it's for entertainment purposes only. The video is accurate as of the posting date but may not be accurate in the future.WATCH OUT FOR SCAMMERS IN THE COMMENTS I do not have a telegram, discord or any tother type of paid group. I will not contact you here or on other platforms. Scammers are using my name and picture. My real profile has a dark background around my name. I will not ask you to contact me, ask you for money or give you any contact info. Do not contact anyone in the comments. PLEASE HELP BY REPORTING AND DELETING ALL THESE SCAMMERS. Thank you!

The practicalities of birthright citizenship being restricted in some states but not others appeared to be a concern of key justices on the US Supreme Court. President Donald Trump has asked the justices to narrow lower court rulings that blocked his executive order limiting automatic citizenship to babies born with at least one parent who's a citizen or permanent resident. Cases and Controversies hosts Greg Stohr and Lydia Wheeler discuss Thursday's arguments and highlight the exchanges that seemed to show the justices are wary of letting Trump start enforcing his restrictions. Do you have feedback on this episode of Cases and Controversies? Give us a call and leave a voicemail at 703-341-3690.

In this episode of Good Morning Liberty, hosts Nate Thurston and Chuck Thompson discuss President Trump's recent speech in Saudi Arabia, highlighting his comments on the Middle East's modernization and peace through negotiation. They also delve into a new book by Jake Tapper and Alex Thompson that reveals concerns about Joe Biden's cognitive decline during his presidency, and discuss the implications of lifting sanctions on Syria. The episode also touches on the role of the media in shaping public perception and foreshadows an upcoming analysis on a new spending bill. (00:00) Introduction (01:25) Trump's Speech and Biden's Mental Decline (03:37) Discussion on Trump's Foreign Policy (07:29) Syria Sanctions and Middle East Diplomacy (18:05) Trump's Speech Highlights (29:28) Interactive Segment and Closing Remarks (30:20) Discussing the Feasibility of Continuing the Podcast (31:04) Introducing the Biden Book Controversy (33:05) Media's Role in Biden's Decline (36:07) Reactions to the Book's Revelations (39:00) Jake Tapper's Involvement and Media Critique (42:32) The White House's Deception and Media's Complicity (49:48) The Future of Media and Political Transparency   Links:   https://gml.bio.link/   YOUTUBE:   https://bit.ly/3UwsRiv   RUMBLE:   https://rumble.com/c/GML   Check out Martens Minute!   https://martensminute.podbean.com/   Follow Josh Martens on X:   https://twitter.com/joshmartens13   Join the private discord & chat during the show!   joingml.com   Bank on Yourself bankonyourself.com/gml   Get FACTOR Today! FACTORMEALS.com/factorpodcast     Good Morning Liberty is sponsored by BetterHelp! Rediscover your curiosity today by visiting Betterhelp.com/GML (Get 10% off your first month)     Protect your privacy and unlock the full potential of your streaming services with ExpressVPN. Get 3 more months absolutely FREE by using our link EXPRESSVPN.com/GML  

We're looking at the proposals for a new line connecting the North Wales Main Line and the Cambrian Coast Line between Bangor and Afon Wen... Are the plans any good? Should they go ahead even if the correct route for a north-south Welsh mainline is at the other side of the country? Way back in Episode 57 we analysed where any future north-south Welsh railway needed to be, and we fleshed those plans out into the Dragon Line/Llinell Y Ddraig in Episode 116. Let's see how this report aligns with that - or doesn't. Download the report here: https://www.gov.wales/sites/default/files/publications/2025-02/re-opening-the-bangor-to-afon-wen-rail-line-feasibility-study.pdf Enjoyed this? Please do consider supporting #Railnatter at https://patreon.com/garethdennis or throw loose change at me via https://paypal.me/garethdennis. Merch at https://garethdennis.co.uk/merch. Join in the discussion at https://garethdennis.co.uk/discord. You can also buy my book #HowTheRailwaysWillFixTheFuture: https://bit.ly/HowTheRailways

In this episode of the California Underground Podcast, hosts Phil and Camille discuss significant political developments in California, focusing on the controversial AB 379 bill aimed at protecting minors from sexual exploitation. They explore Trump's proposal to reopen Alcatraz, the historical context of the prison, as well as hypocritical Democratic politicians like Ted Lieu who claim to be Catholic, yet support ideals that go against Catholic teachings. Are you a Californian who feels isolated and alone in your political views in a deep blue state? Feel like you can't talk about insane taxes, an overbearing government, and radical social experiments without getting a side eye? Then join us on the California Underground Podcast, the most trusted podcast on all things California politics.Original air date  5.6.25*The California Underground Podcast is dedicated to discussing California politics from a place of sanity and rationality.*Chapters04:58 Discussion on Trump's AI Pope Image and Ted Lieu's Reaction11:00 Hypocrisy in Political Statements Regarding Catholicism19:06 Trump's Proposal to Reopen Alcatraz27:19 Exploring the Feasibility of Reopening Alcatraz31:30 In-Depth Analysis of AB 379 and Its Implications37:08 Debating the Age of Consent and Trafficking Laws44:01 Heated Assembly Floor Discussions50:55 The Impact of Public Pressure on Legislation01:01:59 Political Maneuvering and Accountability01:13:35 The Importance of Civic EngagementCheck out our full site for more information about the show at www.californiaunderground.liveCheck out our sponsor for this episode, StopBox, by going to www.stopbox.com/californiaunderground to get 10% off your orderFollow California Underground on Social Media  Instagram: www.instagram.com/californiaunderground X: https://twitter.com/CAUndergoundTik Tok: https://www.tiktok.com/@californiaunderground?_t=8o6HWHcJ1CM&_r=1YouTube: https://www.youtube.com/channel/UCj8SabIcF4AKqEVFsLmo1jA Read about our Privacy Policy: https://www.spotify.com/us/legal/privacy-policy/ 

Dr. Ezra Schwartz (@ezraschwartz10) interviews Dr. Firas Moussa and Mr. Jake Howitt to discuss the IMPROVE-AD Trial, a landmark, multi-institutional study investigating treatment strategies for uncomplicated Type B Aortic Dissection (uTBAD). The IMPROVE-AD Trial is a multicenter randomized trial funded by the NIH/NHLBI that compares thoracic endovascular aortic repair (TEVAR) plus optimal medical therapy (OMT) vs. OMT and surveillance with selective TEVAR in patients with uncomplicated TBAD. The trial aims to address critical gaps in evidence left by prior studies (INSTEAD-XL, ADSORB), with a unique focus on quality of life, cost-effectiveness, and genetic data. Dr. Firas Mussa is a professor and the Chief of Vascular and Endovascular Surgery at McGovern Medical School at UTHealth Houston. He previously served as the Director of the Vascular Surgery Residency and Fellowship programs at NYU Langone Health. Dr. Mussa earned his medical degree from the University of Baghdad, followed by general surgery training at Johns Hopkins University and a vascular surgery fellowship at Baylor College of Medicine. His research focuses on complex aortic pathology, and he serves as the principal investigator of the IMPROVE AD trial. Mr. Jake Howitt is the Community Engagement Co-Chair of the IMPROVE AD trial and a leading patient advocate within the PCORI-funded Aortic Dissection Collaborative. As a survivor of aortic dissection, he is passionate about improving patient-provider communication and raising awareness of hereditary aortic disease. His work emphasizes the importance of education, empathy, and community-building in clinical research and care delivery. Special thank you to Jacob Soucy (@JacobWSoucy). Resources: ·       Treatment of Uncomplicated Type B Aortic Dissection: Optimal Medical Therapy vs TEVAR + Optimal Medical Therapy- https://journals.sagepub.com/doi/10.1177/15385744231184671?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed  ·       INSTEAD Trial - https://pubmed.ncbi.nlm.nih.gov/19996018/ ·       INSTEAD-XL 5-Year Follow-Up - https://pubmed.ncbi.nlm.nih.gov/23922146/ ·       ADSORB Trial - https://pubmed.ncbi.nlm.nih.gov/24962744/ ·       Feasibility of a proposed randomized trial in patients with uncomplicated descending thoracic aortic dissection: Results of worldwide survey - https://pubmed.ncbi.nlm.nih.gov/27823685/ ·       Treatment of AD: Meta-Analysis - https://pubmed.ncbi.nlm.nih.gov/29066151/ ·       TEVAR vs Medical Therapy- https://pubmed.ncbi.nlm.nih.gov/36334259/ ·       IMPROVE AD Trial website - https://improvead.org ·       John Ritter Foundation for Aortic Health - https://johnritterfoundation.org ·       Think Aorta US - https://thinkaorta.us   Follow us @audiblebleeding Learn more about us at https://www.audiblebleeding.com/about-1/ and provide us with your feedback with our listener survey.  *Gore is a financial sponsor of this podcast, which has been independently developed by the presenters and does not constitute medical advice from Gore. Always consult the Instructions for Use (IFU) prior to using any medical device.      

US Gold Corp CEO George Bee talked with Proactive's Stephen Gunnion about the latest developments surrounding the CK Gold Project in southeast Wyoming. The company recently received the final component of its mine operating permit in November, marking a pivotal step forward. Bee explained that US Gold Corp is finalizing optimization work and evaluating flotation technology options, which will feed into a forthcoming feasibility study. This study will build on the previously released pre-feasibility study (PFS), which was based on a gold price of $2,100 per ounce and copper at $4.10 per pound. Bee noted, “The numbers look stellar,” particularly as current gold prices have exceeded $3,000. This price movement, coupled with economic uncertainty and infrastructure developments, supports a favorable outlook for both gold and copper. He also acknowledged that while initial capital costs may rise due to tariffs, the project remains robust even under less favorable scenarios. Bee highlighted the positive market response following the lifting of permitting uncertainty and transparency around the project's economics. After a successful annual shareholder meeting and a notable increase in both share price and market cap, Bee expressed optimism about the project's long-term potential. Visit Proactive's YouTube channel for more video updates. Don't forget to like this video, subscribe to the channel, and enable notifications for future content. #USGoldCorp #CKGoldProject #GoldMining #CopperMining #WyomingMining #MiningStocks #GeorgeBee #GoldPrice #FeasibilityStudy #JuniorMining #ProactiveInvestors

“Everyone's brain is extremely heterogenic, so it's different. You can put five of us in a room; we can all have the same diagnosis of a [glioblastoma multiforme], but all of ours can be different. They're highly aggressive biologically. It's a small area in a hard shell. So trying to get through the blood–brain barrier is different. There's a lot of areas of hypoxia in the brain. There's a lot of pressure there. The microbiology is very different—it's a cold environment versus a hot environment—and then the pathways are just different,” Lori Cappello, MSN, APN-C, CCRP, research advanced practice nurse at the John Theurer Cancer Center of Hackensack Meridian Health in New Jersey, told Jaime Weimer, MSN, RN, AGCNS-BS, AOCNS®, manager of oncology nursing practice at ONS, during a conversation about brain malignancies and caring for patients with them. Music Credit: “Fireflies and Stardust” by Kevin MacLeod Licensed under Creative Commons by Attribution 3.0  Earn 0.5 contact hours of nursing continuing professional development (NCPD) by listening to the full recording and completing an evaluation at courses.ons.org by April 25, 2027. The planners and faculty for this episode have no relevant financial relationships with ineligible companies to disclose. ONS is accredited as a provider of nursing continuing professional development by the American Nurses Credentialing Center's Commission on Accreditation. Learning outcome: Learners will report an increase in knowledge related to brain malignancies and their diagnosis and treatment. Episode Notes  Complete this evaluation for free NCPD.  ONS Podcast™ episodes: Episode 235: Self-Advocacy Skills for Patients Episode 166: Cognitive Behavioral Interventions Help Patients With a Spectrum of Cancer Symptoms ONS Voice articles: Glioblastoma Diagnosis, Treatment, Side Effect Management, and Survivorship Recommendations Blocking Fatty Acid Storage May Induce Glioblastoma Apoptosis Brain Tumor Navigator Role Bridges the Intersection of Cancer and Neuroscience Researchers Tie More Cancers, Mortality to NF1 Disorders Larotrectinib and Other Tumor-Agnostic Targeted Therapies Are Leading Cancer Care Into the Next Frontier McCain Announcement Sheds Light on Nurses' Role in Advance Care Planning ONS book: Manual for Radiation Oncology Nursing Practice and Education (fifth edition) Clinical Journal of Oncology Nursing articles: Implementing a Standardized Educational Tool for Patients With Brain Tumors Undergoing Concurrent Temozolomide and Radiation Therapy Exercise Intervention: A Pilot Study to Assess the Feasibility and Impact on Cancer-Related Fatigue and Quality of Life Among Patients With High-Grade Glioma Society for Neuro-Oncology Musella Foundation End Brain Cancer Initiative Brain Tumor Network American Brain Tumor Association Glioblastoma Research Organization Brain Tumor Funders' Collaborative Optune Gio® website Nurse.org article: Mysterious Brain Tumor Cluster Grows: Another Nurse Diagnosed at Newton-Wellesley Lori Cappello's contact information: lori.cappello@hmhn.org To discuss the information in this episode with other oncology nurses, visit the ONS Communities. To find resources for creating an ONS Podcast Club in your chapter or nursing community, visit the ONS Podcast Library. To provide feedback or otherwise reach ONS about the podcast, email pubONSVoice@ons.org. Highlights From This Episode “A glioblastoma actually is the most predominant brain tumor that we do see. It is the most diagnosed of the brain tumors. And then I would say that an anaplastic astrocytoma is probably the second diagnosed. Historically a GBM, they used to say was probably an elderly patient for these. But we are definitely seeing it diagnosed at a much younger age now, definitely much more prevalent for people under 60.” TS 3:17 “Nine times out of ten, either a patient out of nowhere has a seizure, or they present with what they think are stroke-like symptoms. They noticed that they were slurring, or they were becoming more forgetful, or a family member noticed it and said, ‘Hey, what is going on with you?' But usually they present to the [emergency department], and a [computed tomography] scan is always done first. And lo and behold, something is seen.” TS 4:50 “The only other U.S. Food and Drug Administration-approved treatment that has come along in the last 20 years is a device called Optune Gio, which is an alternating electric field that stops cell division at the mitosis stage.” TS 7:45 “They lose so much of their independence, especially if they don't have a caregiver or help. That is huge. Medication management at home, to making sure that they're taking the medication properly, that they are actually taking their medication. Transportation is another huge problem. Getting to and from appointments is a challenge. Those are big issues—real, day-to-day, simple issues that people don't think about.” TS 17:11 “I think that having a brain tumor is very unique in the fact that you really need a dedicated neuro-oncologist. And depending on where you live, there are not a lot in the area. I actually had a patient that was moving out west, and the closest dedicated neuro-oncologist was four hours from them. … if you're not seeing dedicated neuro oncologists, you might not be getting the best treatment for yourself. So I think that having the resources and helping patients find the best care or the best brain tumor society—and there's a bunch of really good brain tumor groups to help patients find the best resources out there. I think that's really, really important for patients to know or for families to know.” TS 19:17 “So trying to help patients, there are always going to be challenges, and there are always going to be ups and downs. But finding that one person that they can go to, that they trust, that they have a great relationship with, whether at the doctor's office or whatever, and being available to them makes such a difference in their journey. I think that that is the most important for anybody in the journey.” TS 22:08 “With brain, there are going to be expectations. They are going to lose functionality at some point—and preparing them for that thing or preparing them for things that can help themselves. Like sometimes I say, ‘Go to the dollar store, get coloring books,' if they have weakness in one hand. Little tricks of the trade that can help them. About treatment options, going through the side effects, preparing them for whatever they can be prepared for.” TS 22:39 “It is not one of the better cancers to have, but it doesn't immediately mean it's a death sentence, and we shouldn't treat them like they're dying. We shouldn't take away their ability to live just because they were diagnosed with it. We shouldn't take away hope.” TS 25:35 “I think there's not enough discussed about [brain malignancies] and the lack of resources for this. These patients need a lot more resources and are available. There's just not enough available for it.” TS 26:59

Yesterday Health Minister Mark Butler was forced to clarify that there will still be some patients who are charged a gap fee at the GP. Meanwhile at a state level, the LNP government are scrambling to redraw Queensland's hospital building plan after another scathing review. Australian Medical Association of Queensland President Dr Nick Yim told Luke Bradnam on 4BC Breakfast, "when the government did first make their announcement at the very start of the campaign... we've always said that it's quite unlikely that all GPs or 90 per cent of GPs will be bulk billing." "When we surveyed our members, they've told us that if they choose to universally bulk bill, that's actually going to be a loss of 20 to 30 per cent of their revenue." "I guess in this current climate, I'd ask any business owner, any workplace, it's very, very unlikely that medical practice could survive if they have a 20, 30 per cent reduction in revenue," Dr Yim said.See omnystudio.com/listener for privacy information.

Feasibility and acceptability of a six-month exercise and patient education intervention for patients with hip dysplasia: A mixed methods study Jacobsen JS, Thorborg K, Sørensen D, et al. Musculoskelet Sci Pract. 2022;61:102615. doi:10.1016/j.msksp.2022.102615 Due to copyright laws, unless the article is open source we cannot legally post the PDF on the website for the world to download at will. Brought to you by our sponsors at: CSMi – https://www.humacnorm.com/ptinquest Learn more about/Buy Erik/Jason/Chris's courses – The Science PT Support us on the Patreons! Music for PT Inquest: “The Science of Selling Yourself Short” by Less Than Jake Used by Permission Other Music by Kevin MacLeod – incompetech.com: MidRoll Promo – Mining by Moonlight Koal Challenge – Sam Roux

Thinking about buying a block to build on? Before you commit, this episode could save you thousands. Nathan chats with Ryan Giorgiutti, founder of EZ Feasy, about how feasibility reports help you make smarter property decisions. From duplexes to granny flats, Ryan breaks down the hidden factors that can make or break your project. They talk about zoning issues, drainage problems, bushfire risks, and all the things you won't see at an open home.Ryan also shares real examples of projects that went right—and wrong. Whether you're a developer, homeowner, or investor, this episode is packed with insight. Tune in to learn how to spot red flags early and plan with confidence.Topics: ✅ Smart Property Feasibility✅ Hidden Site Constraints✅ DA vs CDC Pathways✅ Pre-Purchase Planning Tips✅ Real Case Studies & Outcomes✅ Why Most People Get It WrongConnect with Ryan Giorgiutti:LinkedIn: https://www.linkedin.com/in/ryangiorgiutti/LinkedIn: https://www.linkedin.com/company/ezfeasy/Website: https://ezfeasy.com.au/ Hosted on Acast. See acast.com/privacy for more information.

In this episode, we sit down once again with Bill Willoughby, CEO of Century Lithium (TSXV: LCE.V, OTCQX: CYDVF), to discuss the latest developments at their Nevada-based lithium project, Angel Island. We cover the company's unique chlor-alkali processing method, recent optimization studies, and the impact of the U.S. government's executive order to accelerate domestic mineral production. Bill shares insights on Century's permitting progress, strategic partnerships, and the potential for significant CAPEX reductions. CHAPTERS

People with aphasia can have problems understanding or using numbers in everyday life - known as functional numeracy difficulties. However, testing this is hard because there are limited published assessments for functional numeracy difficulties for people with aphasia. This study aimed to explore, validate and pilot a wide-ranging, aphasia-friendly functional numeracy assessment to investigate how functional numeracy is impacted by aphasia severity and time pressure demands, and to explore predictors of PWA's functional numeracy.The paper is:Which blueberries are better value? The development and validation of the functional numeracy assessment for adults with aphasia' https://onlinelibrary.wiley.com/doi/full/10.1111/1460-6984.12867 Kerri Ichikowitz, Carolyn Bruce, Vanessa Meitanis, Kelly Cheung, Yekyung Kim, Esther Talbourdet, Caroline NewtonFirst published: 13 March 2023This paper was awarded the IJLCD student prize.Resources:If you would like access to the online version of the Functional Numeracy Assessment, please contact the study authors.The intervention study: Newton, C., Meitanis, V., Bruce, C., & Donlan, C. (2025). Evaluation of the SWAN game-based approach to re-building numeracy skills in aphasia: Feasibility and preliminary findings. https://doi.org/10.31234/osf.io/f7d39_v1 The survey of SLTs: Newton, C., Brancamp, D., & Brancamp, T. (2025). The rehabilitation of numerical processing and calculation in aphasia: An international survey of speech-language pathologists. https://doi.org/10.31234/osf.io/g63j9_v1 Please be aware that the views expressed are those of the guests and not the RCSLT.Please do take a few moments to respond to our podcast survey: uk.surveymonkey.com/r/LG5HC3R

Washington State University scientists working on developing robotic crop pollination technology received a nearly $1 million grant.

For the first time, in a long time, more breweries are closing than opening. One of the success factors for breweries that survive and thrive vs. those who do not, is a feasibility study. Jon Reynolds from Brew Plan Marketing specializes in feasibility studies, market research, and data gathering. In today's podcast, Jon shares trends, growth areas, and the details of how to build a feasibility study for brewery success.  Summary What a feasibility study is and why it's important7 benefits of market analysisResource run-down of brewery data to make informed decisionsResourcesConnect with Jon Reynolds from BrewPlan Marketing, brewplanmarketing@gmail.comGrab the FREE brewery financial planning newsletter

The Idaho Water Resource Board (IWRB) received a staff update on managed recharge operations to benefit Eastern Snake Plain Aquifer (ESPA).

Today I am talking to Professor Alan Brown, Professor of Digital Economy at the University of Exeter and Director of Artificial Intelligence (AI) for Digital Leaders. We talk about how small and medium sized companies can get the best from AI. We cover how AI can help in education. We also talk about the Feasibility, viability and desirability of new solutions. We will look at relationships with technology, how AI can improve education and how adoption of new technology can be affected by people's perceived vulnerability – ultimately the question is how can people learn to trust technology?

Struggling to sort through a mountain of ideas? In this episode of the Honeypot Podcast, Alexander Wennerberg and Fredrik Heghammar dive deep into the crucial step of prioritization in idea management. Learn how to effectively evaluate and rank your team's suggestions using powerful frameworks like the "Three Lenses of Innovation" (viability, feasibility, desirability) and the "Action Board" (impact vs. effort).We discuss practical strategies for involving the right stakeholders, avoiding common pitfalls, and ensuring that your organization focuses on the most impactful initiatives. Discover how to move beyond consensus and implement data-driven decision-making to turn your best ideas into reality.Chapters:00:00 Introduction01:07 Design Thinking and Prioritization02:03 The Four Pillars of Idea Management03:21 The Three Lenses of Innovation (Viability, Feasibility, Desirability)05:47 The Magic Number Three and Google's Criteria06:38 The Action Board: Impact vs. Effort07:40 Eisenhower Matrix and Simplification09:32 Overcoming Complex Processes11:38 The Importance of Data and Information13:17 Risk Minimization and Prioritization15:32 Involving the Right People in Prioritization17:50 Business Model Canvas and Stress Testing Ideas20:13 Scaling Ideas and Finding Solutions22:16 Using Hives for Tailored Workflows23:57 Comparing Management and Employee Perspectives26:46 The Importance of Daily Idea Evaluation27:06 Final Recommendations: Estimation and Simplicity#IdeaManagement #Innovation #Prioritization #DesignThinking #BusinessStrategy #ProductManagement #ProjectManagement #HivesCo #Entrepreneurship #StartupTips #EmployeeIdeas #EmployeeSuggestions #ContinuousImprovementCheck out more on idea management at Hives.co!

In this episode, we speak with Matteo Mirolo, Director of Strategy & External Relations at Contrails.org, a science-led nonprofit initiative aimed at transforming contrail research into practical climate action. Mirolo discusses:The substantial climate impact of contrails, which are responsible for 1-2% of human-caused global warming and have roughly the same warming effect as all aviation CO2 emissions since the jet age.The concentrated nature of the problem, with just 5% of flights causing about 80% of aviation's contrail warming effect, primarily over Europe, North America, and the North Atlantic.Contrails.org's three-pillar approach focusing on science (improving understanding of contrail impacts), technology (developing open-source tools and protocols), and adoption (raising awareness and fostering incentives).The cost-effectiveness of contrail mitigation compared to other decarbonisation options, with studies suggesting only 0.11% extra fuel burn across airline fleets.The vision for seamless integration into airline operations, where contrail avoidance becomes as routine as avoiding turbulence or adverse weather.Contrails.org seeks to be an open, collaborative space, with Mirolo likening it to “a tent under which people can put their furniture.” Its goal is to address the contrail issue through collective effort, recognising that effective management requires coordination across the aviation sector.If you LOVED this episode, you'll also love the conversation we had with Alejandra Martín Frías, Head of Sustainability Research at FLIGHTKEYS, who shared insights into the company's research on contrail avoidance. Check it out here. Learn more about the innovators who are navigating the industry's challenges to make sustainable aviation a reality, in our new book ‘Sustainability in the Air'. Click here to learn more.Feel free to reach out via email to podcast@simpliflying.com. For more content on sustainable aviation, visit our website green.simpliflying.com and join the movement. It's about time.Links & More:Contrails.orgHow airplane contrails are helping make the planet warmer - Yale e360 Feasibility of contrail avoidance in a commercial flight planning system: an operational analysis - IOPscience Understanding contrail management: opportunities, challenges, and insights - RMIThis episode is brought to you by 4AIR. 4AIR is leading the way with the industry's first framework to address aviation's climate impact—offering clear, verifiable pathways to reduce and counteract aircraft emissions. For more information, please visit: https://www.4air.aero/

Chapel Hill Mayor Jess Anderson spoke with 97.9 The Hill's Andrew Stuckey on Thursday, March 6, discussing town news and events. She recapped Wednesday night's Chapel Hill Town Council Meeting, which included an update on the town's public housing, an update on outside agencies that receive town funding. She also discussed the recently announced soccer friendly coming to Chapel Hill this summer, as the Mexican National Team will face the Turkish National Team. She previewed other upcoming town events, and more. The post Chapel Hill: Public Housing Update, Rail-Trail Feasibility, Summer Soccer appeared first on Chapelboro.com.

Notes from James: What if I told you that we could eliminate the IRS, get rid of personal income taxes completely, and still keep the government funded? Sounds impossible, right? Well, not only is it possible, but historical precedent shows it has been done before. I know what you're thinking—this sounds insane. But bear with me. The IRS collects $2.5 trillion in personal income taxes each year. But what if we could replace that with a national sales tax that adjusts based on what you buy? Under my plan: Necessities (food, rent, utilities) 5% tax Standard goods (clothes, furniture, tech) 15% tax Luxury goods (yachts, private jets, Rolls Royces) 50% tax And boom—we don't need personal income taxes anymore! You keep 100% of what you make, the economy booms, and the government still gets funded. This episode is a deep dive into how this could work, why it's better than a flat tax, and why no one in government will actually do this (but should). Let me know what you think—and if you agree, share this with a friend (or send it to Trump). Episode Description: What if you never had to pay personal income taxes again? In this mind-bending episode of The James Altucher Show, James tackles a radical idea buzzing from Trump, Elon Musk, and Howard Lutnick: eliminating the IRS. With $2.5 trillion in personal income taxes on the line, is it even possible? James says yes—and he's got a plan. Digging into history, economics, and a little-known concept called “money velocity,” James breaks down how the U.S. thrived in the 1800s without income taxes, relying on tariffs and “vice taxes” on liquor and tobacco. Fast forward to today: the government rakes in $4.9 trillion annually, but spends $6.7 trillion, leaving a gaping deficit. So how do you ditch the IRS without sinking the ship? James unveils his bold solution: a progressive national sales tax—5% on necessities like food, 15% on everyday goods like clothes, and a hefty 50% on luxury items like yachts and Rolls Royces. Seniors and those on Social Security? They'd pay nothing. The result? The government still nets $2.5 trillion, the economy grows by $3.7 trillion thanks to unleashed consumer spending, and you keep more of your hard-earned cash. No audits, no accountants, just taxes at the cash register. From debunking inflation fears to explaining why this could shrink the $36 trillion national debt, James makes a compelling case for a tax revolution. He even teases future episodes on tariffs and why a little debt might not be the enemy. Whether you're a skeptic or ready to tweet this to Trump, this episode will change how you see taxes—and the economy—forever. What You'll Learn: The history of taxes in America—and how the country thrived without an income tax in the 1800s Why the IRS exists and how it raises $2.5 trillion in personal income taxes every year How eliminating income taxes would boost the economy by $3.75 trillion annually My radical solution: a progressive national sales tax—and how it works Why this plan would actually put more money in your pocket Would prices skyrocket? No. Here's why. Timestamps: 00:00 Introduction: Trump's Plan to Eliminate the IRS 00:22 Podcast Introduction: The James Altucher Show 00:47 The Feasibility of Eliminating the IRS 01:27 Historical Context: How the US Raised Money in the 1800s 03:41 The Birth of Federal Income Tax 07:39 The Concept of Money Velocity 15:44 Proposing a Progressive Sales Tax 22:16 Conclusion: Benefits of...

Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Safety and Feasibility of 3D Intracardiac Echocardiography in Guiding Left Atrial Appendage Occlusion With WATCHMAN FLX

Jacob welcomes Tomas back onto the podcast in the wake of China's announcement that licences will now be required to export 20 tungsten, tellurium, bismuth, indium and molybdenum-related products to "safeguard national security interests.” Tomas and Jacob talk about how to align government priorities to secure access to materials and the complexities around building capacity in a deglobalizing world where demand for materials has literally never been more intense.--Timestamps:(00:00) – Intro (05:25) – Government priorities(11:12) – China and critical minerals(21:32) – Economics of mineral refining(31:27)– Social license to operate(38:19) – Feasibility of climate friendly goals(43:34) – Aluminum and REE case studies(52:35) – Food for thought--Jacob Shapiro Site: jacobshapiro.comJacob Twitter: x.com/JacobShapCI Site: cognitive.investmentsSubscribe to the Newsletter: bit.ly/weekly-sitrep--The Jacob Shapiro Show is produced and edited by Audiographies LLC. More information at audiographies.com --Jacob Shapiro is a speaker, consultant, author, and researcher covering global politics and affairs, economics, markets, technology, history, and culture. He speaks to audiences of all sizes around the world, helps global multinationals make strategic decisions about political risks and opportunities, and works directly with investors to grow and protect their assets in today's volatile global environment. His insights help audiences across industries like finance, agriculture, and energy make sense of the world.Cognitive Investments is an investment advisory firm, founded in 2019 that provides clients with a nuanced array of financial planning, investment advisory and wealth management services. We aim to grow both our clients' material wealth (i.e. their existing financial assets) and their human wealth (i.e. their ability to make good strategic decisions for their business, family, and career).--This podcast uses the following third-party services for analysis: Podtrac - https://analytics.podtrac.com/privacy-policy-gdrp

Testing a Mobile Mindful Eating Intervention Targeting Craving-Related Eating: Feasibility and Proof of ConceptIn this episode, Dr. Jud Brewer and colleagues discuss the results of a groundbreaking study testing a smartphone-based mindful eating intervention. Designed to target craving-related eating through mindfulness and operant conditioning principles, the intervention demonstrated significant reductions in food cravings, emotional eating, and overeating among overweight and obese women. Dr. Brewer explores how this scalable, low-burden approach leverages awareness to disrupt habitual eating patterns, reduce cravings, and support sustainable weight management. Tune in to learn how mobile mindfulness tools can reshape eating behaviors and promote healthier relationships with food.Full Reference:Mason, A. E., Jhaveri, K., Cohn, M., & Brewer, J. A. (2017). Testing a mobile mindful eating intervention targeting craving-related eating: Feasibility and proof of concept. Journal of Behavioral Medicine. https://doi.org/10.1007/s10865-017-9884-5Let's connect on Instagram

In this episode of NucleCast, Adam welcomes Chris Stone to discuss the recent executive order regarding the Iron Dome for America . They explore the implications of the order, the differences between the Israeli Iron Dome and the proposed American system, and the feasibility of developing a comprehensive missile defense system. The conversation also delves into budget considerations, the role of space in national defense, and innovative approaches to missile defense, emphasizing the urgency of addressing vulnerabilities in the face of emerging threats.Christopher Stone is a prominent figure in space policy, currently serving as a Senior Fellow for Space Deterrence at the National Institute for Deterrence Studies, where he focuses on research related to space warfare strategies and deterrence, particularly in the context of great power competition; he previously held a position as a Special Assistant to the Deputy Assistant Secretary of Defense for Space Policy at the Pentagon, giving him significant experience in the field of U.S. space policy development at a high level.Chapters00:00 Introduction to Iron Dome for America03:13 Understanding the Executive Order05:52 Comparing Iron Dome Systems: Israel vs. America09:08 Feasibility of Building a Comprehensive Defense System11:51 Budget Considerations and Strategic Implications15:01 The Role of Space in National Defense18:05 Innovative Approaches to Missile Defense20:55 The Future of Space-Based Interceptors23:55 Final Thoughts and Call to ActionSocials:Follow on Twitter at @NucleCastFollow on LinkedIn: https://linkedin.com/company/nuclecastpodcastSubscribe RSS Feed: https://rss.com/podcasts/nuclecast-podcast/Rate: https://podcasts.apple.com/us/podcast/nuclecast/id1644921278Email comments and topic/guest suggestions to NucleCast@anwadeter.org

ThunderClan deals with the aftermath of battle - and starts to consider what the sun going out could mean.Book: Warriors, Series 3: Power of Three #4: EclipseSupport us on Ko-fi!WCWITCast Ko-fiFollow us on BlueSky!WCWITCastFollow us on Instagram!WCWITCast What We Are Reading (Not Sponsored):Escape From St Hell: My Trans Life Levels Up by Lewis Hancox Cat Fact Sources:Researchers put little hats on cats to measure their brainwaves | Popular ScienceNon-invasive electroencephalography in awake cats: Feasibility and application to sensory processing in chronic pain - ScienceDirectYoutube - Narby Pompom Cat Hat - Catventurous CrochetCat scans: Canadian scientists found an adorable new way to study cat brain activityOsteoarthritis in Cats: More Common Than You Think | FDAOsteoarthritis in Cats - American College of Veterinary SurgeonsResearchers Use Tiny Crochet Hats to Investigate Chronic Pain in CatsMusic:The following music was used for this media project:Happy Boy Theme by Kevin MacLeod Link: https://incompetech.filmmusic.io/song/3855-happy-boy-themeLicense:http://creativecommons.org/licenses/by/4.0/

In this week's episode of the Coin Stories News Block, we cover these major headlines related to Bitcoin and global finance: Trump Signs Order to Create U.S. Sovereign Wealth Fund David Sacks: “Stablecoins Could Lower Long-term Rates” Czech Republic Ends Capital Gains Tax on Bitcoin FDIC to Update Crypto Banking Guidelines and more! ---- Join my mailing list and subscribe to our free newsletter: thenewsblock.substack.com  ---- Natalie's Promotional Links:  Coin Stories is powered by Genius Group (NYSE American $GNS). Genius is a Bitcoin-first business delivering AI powered, education and acceleration solutions for the future of work. Learn more at https://www.geniusgroup.ai/btc-newsletter. Secure your Bitcoin with collaborative custody and set up your inheritance plan with Casa: https://www.casa.io/natalie  For easy, low-cost, instant Bitcoin payments, I use Speed Lightning Wallet. Get 5000 sats when you download using this link and promo code COINSTORIES10: https://www.speed.app/sweepstakes-promocode/ River is where I DCA weekly and buy Bitcoin with the lowest fees in the industry: https://partner.river.com/natalie  Safely self-custody your Bitcoin with Coinkite and the ColdCard Wallet. Get 5% off: https://store.coinkite.com/promo/COINSTORIES Master your Bitcoin self-custody with 1-on-1 help and gain peace of mind with the help of The Bitcoin Way: https://www.thebitcoinway.com/natalie Bitcoin 2025 is heading to Las Vegas May 27-29th! Join me for my 4th Annual Women of Bitcoin Brunch! Get 10% off Early Bird passes using the code HODL: https://tickets.b.tc/affiliate/hodl/event/bitcoin-2025   Protect yourself from SIM Swaps that can hack your accounts and steal your Bitcoin. Join America's most secure mobile service, trusted by CEOs, VIPs and top corporations: https://www.efani.com/natalie  Connect with Bitcoiners and Bitcoin merchants wherever you live and travel on the Orange Pill App: https://signup.theorangepillapp.com/opa/natbrunell ---- References mentioned in the episode:  Trump Executive Order to Create Soveriegn Wealth Fund Trump Signs Order to Create Sovereign Wealth Fund  Howard Lutnick Personally Owns A Lot of Bitcoin  Cantor Fitzgerald Announces Bitcoin Financing Business David Sacks Studying the Feasibility of Bitcoin Reserve  Senator Bill Hagerty's New Stablecoin Bill  Senator Hagerty Announces New Stablecoin Bill  David Sacks' Comments on Stablecoin Legislation Tether's Q4 2024 Attestation Paolo Ardoino Says Tether Won't Hold Long-duration  Bessent Says Focus On Lowering 10-Year Treasury Yields Czech Republic Eliminates Taxes on Bitcoin  Breez Report on the State of Bitcoin Payments  FDIC Releases Correspondence on Operation Chokepoint FDIC Set to Revise Guidelines for Banks on Digital Assets Hester Peirce's Policy Statement on Cryptocurrencies  Tiger 21 CEO Says It Holds $6 Billion in Digital Assets  MicroStrategy Rebrands to Strategy  Trump's Media Company to Launch Bitcoin ETF ARK Invest's Big Ideas 2025 Report ---- This podcast is for educational purposes and should not be construed as official investment advice. ---- VALUE FOR VALUE — SUPPORT NATALIE'S SHOWS Strike ID https://strike.me/coinstoriesnat/ Cash App $CoinStories   #money #Bitcoin #investing

In the world of nonprofit fundraising, few topics carry as much weight—or as much uncertainty—as capital campaigns. In this riveting conversation, cohosts Julia Patrick and Wendy F. Adams sit down with the esteemed Steven Shattuck, Director of Engagement at Capital Campaign Pro, to pull back the curtain on the most pressing capital campaign insights, fears, and strategies that can make or break a nonprofit's fundraising success.Steven, a leading voice in nonprofit innovation and the author of ‘Robots Make Bad Fundraisers', takes the audience into the why and how of capital campaigns, exploring feasibility studies, consultant roles, donor engagement, and the key intersection between #AI and fundraising. As capital campaigns often mean a seismic financial undertaking, many nonprofit leaders hesitate, fearing failure, funding shortages, or strategic missteps. In his conversation with cohosts Julia Patrick and Wendy Adams, Steven debunks myths and presents data-driven best practices to demystify the process.A particularly eye-popping moment in the chat is the revelation that ‘96% of nonprofits conducting capital campaigns reported satisfaction with their results—even if they didn't reach their full goal'. Why? Because the ancillary benefits, from strengthening donor relationships to refining their internal fundraising systems, turned out to be just as critical as the dollars raised.A major takeaway? Feasibility studies are not just about testing fundraising goals—they are an opportunity to connect with major donors and lay the groundwork for campaign success. As Steven describes . . ."You're going to come out of the process having a better idea of what you can raise, because that's what you're doing—you're testing the goal, you're testing the case for support, and you're talking to major donors."From the role of campaign consultants to emerging technology's influence on fundraising success, this episode is a masterclass for any nonprofit leader looking to navigate the high-stakes of capital campaigns with confidence and more knowledge. #NonprofitFundraising #CapitalCampaigns #FeasibilityMattersFind us Live daily on YouTube!Find us Live daily on LinkedIn!Find us Live daily on X: @Nonprofit_ShowOur national co-hosts and amazing guests discuss management, money and missions of nonprofits! 12:30pm ET 11:30am CT 10:30am MT 9:30am PTSend us your ideas for Show Guests or Topics: HelpDesk@AmericanNonprofitAcademy.comVisit us on the web:The Nonprofit Show

Welcome to another episode of Supra Insider. This time, Marc and Ben sat down with Irene Yu, founder and CEO of Skiplevel, professional training designed to teach PMs how to become more technical without learning to code. In this conversation, they explored Irene's journey from Amazon engineer to entrepreneur, the communication challenges between PMs and engineers, and how Skiplevel is helping mitigate those challenges. They also discussed the rise of AI features in product development, exploring how PMs can handle edge cases, learn critical AI concepts, and avoid the dreaded "demo trap." Irene also revealed how she used AI to build a personalized therapist and life coach. This episode is packed with valuable takeaways for PMs, engineers, and product leaders looking to level up their collaboration and technical skills.All episodes of the podcast are also available on Spotify, Apple and YouTube.New to the pod? Subscribe below to get the next episode in your inbox

SA Soldiers in DRC: A Year of Warnings Ignored, 14 Lives Lost – Experts Question Feasibility of Mission by Radio Islam

o far everything is on track for a fall 2026 opening of the school if the congregation so decides in the voters meeting to move forward. Stay tuned for the announcement of that date. School Feasibility Committee: Glen Cork, Lonn Poage, Ana Hiel, Katie Luttinen, Pastor Mike and Pastor Scott School Feasibility Genesis Project Report: https://www.ascension-lcms.org/_files/ugd/f0f9a9_1c57897544494aecac4745b1a6ce677b.pdf

Interview with Daniel Major, CEO of GoviEx Uranium Inc.Our previous interview: https://www.cruxinvestor.com/posts/goviex-uranium-tsxvgxu-positioning-for-production-in-2028-5872Recording date: 29th January 2025Goviex Uranium (TSXV: GXU) presents a timely opportunity for investors to gain exposure to the next uranium bull market through its flagship Muntanga project in Zambia. With a recently completed bankable feasibility study (BFS) demonstrating robust project economics, Goviex is well-positioned to bring a significant new source of uranium production online just as the market is projected to swing into a widening supply deficit.The Muntanga BFS, released in January 2025, confirms the viability of a large-scale, low-cost, open-pit uranium mining operation. The study outlines a straightforward mining and processing plan, utilizing conventional open pit truck and shovel mining to feed an on-off heap leach circuit. Muntanga benefits from several key advantages that contribute to its strong economic profile:High-grade, near-surface mineralization hosted in soft, porous sandstones allows for low-strip-ratio mining and coarse crushing to a P80 of 25 millimeters. This reduces mining and processing costs compared to many other uranium projects.The on-off heap leach process achieves quick leach cycles and high recoveries exceeding 90%, further enhancing project economics. The leach circuit has been designed to handle Zambia's seasonal rainfall patterns, with multiple pads to optimize loading, leaching, rinsing, and unloading cycles.Ready access to key infrastructure, including roads, water, and hydroelectric power, streamlines project development and reduces initial capital costs. Goviex can focus its efforts and capital on the core mining and processing facilities.Mining permits have already been secured, significantly de-risking the project. The company expects to receive final environmental approvals within 6 months of submitting its environmental and social impact assessment, which is planned for the end of Q1 2023.Strong local community support provides Goviex with a social license to operate. The company is working closely with local stakeholders to implement a fair and equitable relocation plan for a small number of households, with the aim of maximizing employment and economic development opportunities for the wider community.With a robust BFS in hand, Goviex is now shifting its focus to securing project financing and long-term offtake agreements. The company is seeing strong interest from lenders, particularly South African banks that have recently returned to mining finance. Goviex is pursuing a mix of debt and equity financing, with the aim of minimizing dilution while maintaining a conservative capital structure.On the offtake front, Goviex is leveraging its relationships with global nuclear utilities to negotiate long-term contracts with pricing that reflects the emerging supply deficit in the uranium market. The company is taking a flexible approach to contracting, with a willingness to commit a portion of its production to market-related pricing mechanisms that provide exposure to rising spot prices.For investors, Goviex presents a compelling opportunity to gain leveraged exposure to the next leg up in the uranium market cycle. With a large, low-cost, advanced-stage project in a mining-friendly jurisdiction, Goviex is well-positioned to become a leading supplier of uranium as demand from nuclear energy grows. While risks remain, particularly around securing financing in a challenging market environment, the potential rewards for investors who position themselves ahead of the next uranium bull market are substantial.In conclusion, Goviex Uranium offers investors a unique opportunity to participate in the development of a world-class uranium deposit just as the market is poised for a significant upturn. With a strong project economics, an experienced management team, and a clear path to production, Goviex is a company to watch in the uranium space.—View GoviEx Uranium's company profile: https://www.cruxinvestor.com/companies/goviex-uraniumSign up for Crux Investor: https://cruxinvestor.com

In this episode of Wicked Problems, host Richard Delevan interviews Laurent Segalen, co-host of Redefining Energy, about his North Atlantic Transmission One - Link project. The discussion covers the project's ambitious goal of connecting the energy grids of North America and Europe via a 6 GW undersea cable to increase energy security and resilience, especially in a world increasingly dependent on renewables. Laurent shares his personal journey that led him to this project, including the influence of key historical events and past experiences in energy trading and investment. The conversation touches on the technical, financial, and geopolitical aspects of the project, as well as the challenges and feasibility studies conducted. The episode concludes with insights into the project's potential security implications and future developments.00:00 Introduction to Wicked Problems00:45 International Energy Connections01:57 The Future of Global Energy Trade03:58 Interview with Laurent Seguelin04:51 Laurent's Early Influences11:43 The Birth of Scope 216:46 The North Atlantic Transmission Project24:19 Feasibility and Future Prospects26:43 Starting the Project: Initial Challenges and Collaborations27:54 Wind Data Analysis: Newfoundland and Ireland28:51 Hydro and Wind Energy Developments30:55 Investor Discussions and Independent Reports34:34 Technical and Logistical Considerations40:53 Cost and Feasibility of the Project45:56 Security Concerns and Strategic Importance48:14 Final Thoughts and Future Outlook51:54 Conclusion and Closing Remarks Hosted on Acast. See acast.com/privacy for more information.

Welcome to a new episode of Business Lunch! In this episode, Roland Frasier and Ryan Deiss discuss Elon Musk's unique approach to problem-solving, where he reportedly solves his companies' biggest problems in a matter of weeks. They analyze the pros and cons of Musk's leadership style, including his willingness to make tough decisions and the potential impact on employees. The hosts also explore whether this approach can be replicated by other business leaders.Highlights:"He just came in there and went just ape, you know, and kind of gutted everybody who was essentially middle management.""The fundamental job, the single most important job that any CEO has, is determining what is the company's right next thing.""I do love the idea of saying, like, we are going to solve this problem in weeks, to say that every single thing that is our biggest problem can always be solved in a singular week.""If you're a leader, and if you decide that you're going to take on the role of solving a particular problem in your team, I don't think that's necessarily a bad thing, because, frankly, your people probably are above full capacity already."Timestamps:00:00 - Elon Musk's Approach to Problem-Solving01:20 - Musk's Ability to Solve Problems Quickly03:08 - Identifying the Real Problem07:03 - Feasibility of Musk's Approach09:01 -Downsides of Musk's "Demon Mode"12:38 - The CEO's Role in Determining the Right Next Thing13:40 - Shortening the Unit of Measurement15:00 - Empowering Middle Management20:00 - Communicating the Problem-Solving Approach26:35 - The Sustainability of Elon Musk's ApproachCONNECT • Ask Roland a question HERE.RESOURCES:• 7 Steps to Scalable workbook • Get my book, Zero Down, FREETo learn more about Roland Frasier

00:00: Outline 00:53: P1, P2, P3 03:14: Feasibility study 04:35: DJ Seo comments 06:20: Academic work 07:18: Bad reporting- Rachel Levy 10:15: Canada trial- international expansion 12:02: Elon talk at CNS 13:46: Please follow and subscribe! Jan 8, 2025: CES by Mark Penn, CEO of Stagwell: https://x.com/ElonClipsX/status/1877222791713337623 Jan 7, 2025: Elon Announces More International Expansion: https://x.com/NeuraPod/status/1876708688242589775 Nov 25, 2024: Neuralink's CONVOY Study Announcement: https://x.com/neuralink/status/1861107594645119006 Nov 22, 2024: Romina's Offer: https://x.com/RominaNejad/status/1859996818601652667 Nov 20, 2024: Neuralink's Canadian Trial Announcement: https://x.com/neuralink/status/1859321866944401727 Nov 20, 2024: University Health Network Announcement: https://x.com/UHN/status/1859324169072353488 Sep 29, 2024: Elon Talks at Congress of Neurosurgeons Meeting: https://youtu.be/huxf36QKbI0?si=oQeksONwxG24Iv9G&t=1710 April 2022: Neura Pod Episode: https://www.youtube.com/watch?v=3qUhEXwrL74&t=1003s&ab_channel=NeuraPod%E2%80%93Neuralink Apply for Neuralink's Patient Registry: https://neuralink.com/patient-registry/

This week, Aebhric O'Kelly talks with Dennis Jarema from the Prolonged Field Care Working Group. They discuss his journey from military service to nursing, emphasising the importance of prolonged field care in austere environments. They discuss the challenges faced in military medicine, the evolution of medical practices, and the establishment of the Prolonged Field Care Working Group. The conversation highlights the need for seamless integration of nursing care in emergencies and the importance of training and communication in improving patient outcomes. This conversation delves into the evolving nature of mnemonics in prolonged field care, the challenges faced in conducting research in austere environments, and the need for better communication and collaboration among practitioners and researchers. The discussion highlights the importance of mastering basic skills, avoiding training scars, and engaging volunteers to enhance the effectiveness of the Prolonged Field Care Working Group. The speakers emphasise the necessity of practical training and the development of a clearinghouse for sharing knowledge and resources in the field of austere medicine. Takeaways How Dennis' military background shaped his approach to medicine. The transition from Special Forces medic to nursing was driven by a desire for long-term patient care. Nursing provides essential skills for prolonged field care in austere environments. Understanding when to transition from emergency care to nursing care is crucial. The Prolonged Field Care Working Group was established to address gaps in military medical training. Training must include practical demonstrations of prolonged field care techniques. Communication and a common language are vital in multi-agency medical responses. The evolution of medical practices in the field reflects advancements in hospital medicine. There is a need for a combined paramedic-nurse training program in the U.S. Learning from international practices can enhance U.S. military medical training. Mnemonics in prolonged field care must evolve with practice. Research in prolonged field care faces significant challenges. There is a need for better communication between researchers and practitioners. Feasibility studies are crucial for understanding prolonged field care. Collaboration is essential for advancing research in austere medicine. The PFC Working Group plays a vital role in the community. Practical skills training is often lacking in current education. Engaging volunteers is key to the success of the PFC Working Group. Mastering the basics is fundamental for new practitioners. Experience is critical for recognising early signs of patient distress. Chapters 00:00 Introduction to Prolonged Field Care 00:45 Dennis' Military Journey 05:08 Transitioning to Nursing 10:52 The Importance of Nursing in Prolonged Care 17:11 Prolonged Field Care Working Group Origins 20:22 Challenges in Prolonged Field Care 26:35 Evolution of Medical Practices in the Field 29:58 Evolving Mnemonics in Prolonged Field Care 30:57 Challenges in Research for Prolonged Field Care 32:26 Bridging the Gap Between Research and Practice 34:52 The Need for Feasibility Studies 36:18 Collaboration in Prolonged Field Care Research 38:14 Establishing a Clearinghouse for Communication 40:36 Future Directions for the PFC Working Group 42:36 The Role of the PFC Working Group 44:03 Developing Practical Skills in Prolonged Field Care 45:32 Engaging Volunteers in the PFC Community 48:28 Mastering the Basics of Prolonged Field Care 50:55 Avoiding Training Scars in Medical Training 54:50 The Future of Prolonged Field Care Education 55:47 Advice for New Practitioners in Austere Medicine

1UNITED STATES BANKRUPTCY COURTSOUTHERN DISTRICT OF TEXASHOUSTON DIVISIONIn re:INTRUM AB, et al.,1Debtors.Chapter 11Case No. 24-90575 (CML)(Jointly Administered)NOTICE OF APPEALPursuant to 28 U.S.C. § 158(a) and Federal Rules of Bankruptcy Procedure 8002 and 8003,notice is hereby given that the Ad Hoc Committee of holders of 2025 notes issued by Intrum AB(the “AHC”) hereby appeals to the United States District Court for the Southern District of Texasfrom (i) the Order Denying Motion of the Ad Hoc Committee of Holders of Intrum AB Notes Due2025 to Dismiss Chapter 11 Cases Pursuant to 11 U.S.C. § 1112(b) and Federal Rule ofBankruptcy Procedure 1017(f)(1) (ECF No. 262) (the “Motion to Dismiss Order”) and (ii) theOrder (I) Approving Disclosure Statement and (II) Confirming Joint Prepackaged Chapter 11Plan of Intrum AB and Its Affiliated Debtor (Further Technical Modifications) (ECF No. 263) (the“Confirmation Order”). A copy of the Motion to Dismiss Order is attached as Exhibit A and acopy of the Confirmation Order is attached as Exhibit B. Additionally, the transcript of theBankruptcy Court's oral ruling accompanying the Motion to Dismiss Order and ConfirmationOrder (ECF No. 275) is attached as Exhibit C.Below are the names of all parties to this appeal and their respective counsel:1 The Debtors in these Chapter 11 Cases are Intrum AB and Intrum AB of Texas LLC. The Debtors'service address in these Chapter 11 Cases is 801 Travis Street, Ste 2101, #1312, Houston, TX 77002.Case 24-90575 Document 296 Filed in TXSB on 01/13/25 Page 1 of 62I. APPELLANTA. Name of Appellant:The members of the AHC include:Boundary Creek Master Fund LP; CF INT Holdings Designated Activity Company; CaiusCapital Master Fund; Diameter Master Fund LP; Diameter Dislocation Master Fund II LP; FirTree Credit Opportunity Master Fund, LP; MAP 204 Segregated Portfolio, a segregated portfolioof LMA SPC; Star V Partners LLC; and TQ Master Fund LP.Attorneys for the AHC:QUINN EMANUEL URQUHART & SULLIVAN, LLPChristopher D. Porter (SBN 24070437)Joanna D. Caytas (SBN 24127230)Melanie A. Guzman (SBN 24117175)Cameron M. Kelly (SBN 24120936)700 Louisiana Street, Suite 3900Houston, TX 77002Telephone: (713) 221-7000Facsimile: (713) 221-7100Email: chrisporter@quinnemanuel.comjoannacaytas@quinnemanuel.commelanieguzman@quinnemanuel.comcameronkelly@quinnemanuel.com-and-Benjamin I. Finestone (admitted pro hac vice)Sascha N. Rand (admitted pro hac vice)Katherine A. Scherling (admitted pro hac vice)295 5th AvenueNew York, New York 10016Telephone: (212) 849-7000Facsimile: (212) 849-7100Email: benjaminfinestone@quinnemanuel.comsascharand@quinnemanuel.comkatescherling@quinnemanuel.comB. Positions of appellant in the adversary proceeding or bankruptcy case that isthe subject of this appeal:CreditorsCase 24-90575 Document 296 Filed in TXSB on 01/13/25 Page 2 of 63II. THE SUBJECT OF THIS APPEALA. Judgment, order, or decree appealed from:The Order Denying Motion of the Ad Hoc Committee of Holders of Intrum AB Notes Due2025 to Dismiss Chapter 11 Cases Pursuant to 11 U.S.C. § 1112(b) and Federal Rule ofBankruptcy Procedure 1017(f)(1) (ECF No. 262); the Order (I) Approving Disclosure Statementand (II) Confirming Joint Prepackaged Chapter 11 Plan of Intrum AB and Its Affiliated Debtor(Further Technical Modifications) (ECF No. 263); and the December 31, 2024 Transcript of OralRuling Before the Honorable Christopher M. Lopez United States Bankruptcy Court Judge (ECFNo. 275).B. The date on which the judgment, order, or decree was entered:The Motion to Dismiss Order and the Confirmation Order were entered on December 31,2024. The Court issued its oral ruling accompanying the Motion to Dismiss Order and theConfirmation Order on December 31, 2024.III. OTHER PARTIES TO THIS APPEALIntrum AB and Intrum AB of Texas LLCMILBANK LLPDennis F. Dunne (admitted pro hac vice)Jaimie Fedell (admitted pro hac vice)55 Hudson YardsNew York, NY 10001Telephone: (212) 530-5000Facsimile: (212) 530-5219Email: ddunne@milbank.comjfedell@milbank.com–and–Andrew M. Leblanc (admitted pro hac vice)Melanie Westover Yanez (admitted pro hac vice)1850 K Street, NW, Suite 1100Washington, DC 20006Telephone: (202) 835-7500Facsimile: (202) 263-7586Email: aleblanc@milbank.commwyanez@milbank.com–and–PORTER HEDGES LLPJohn F. Higgins (SBN 09597500)Case 24-90575 Document 296 Filed in TXSB on 01/13/25 Page 3 of 64Eric D. Wade (SBN 00794802)M. Shane Johnson (SBN 24083263)1000 Main Street, 36th FloorHouston TX 77002Telephone: (713) 226-6000Facsimile: (713) 226-6248Email: jhiggins@porterhedges.comewade@porterhedges.comsjohnson@porterhedges.comIV. OTHER PARTIES THAT MAY HAVE AN INTEREST IN THIS APPEALThe following chart lists certain parties that are not parties to this appeal, but that may havean interest in the outcome of the case. These parties should be served with notice of this appealby the Debtors who are aware of their identities and best positioned to provide notice.All Other Creditors of the Debtors, Including, But Not Limited To:• Certain funds and accounts managed by BlackRock Investment Management (UK)Limited or its affiliates;• Capital Four;• Davidson Kempner European Partners, LLP;• Intermediate Capital Managers Limited;• Mandatum Asset Management Ltd;• H.I.G. Capital, LLC;• Spiltan Hograntefond; Spiltan Rantefond Sverige; and Spiltan Aktiefond Stabil;• The RCF SteerCo Group;• Swedbank AB (publ).Any Holder of Stock of the Debtors• Any holder of stock of the Debtors, including their successors and assigns.Case 24-90575 Document 296 Filed in TXSB on 01/13/25 Page 4 of 65Respectfully submitted this 13th day of January, 2025.QUINN EMANUEL URQUHART &SULLIVAN, LLP/s/ Christopher D. PorterChristopher D. Porter (SBN 24070437)Joanna D. Caytas (SBN 24127230)Melanie A. Guzman (SBN 24117175)Cameron M. Kelly (SBN 24120936)700 Louisiana Street, Suite 3900Houston, TX 77002Telephone: (713) 221-7000Facsimile: (713) 221-7100Email: chrisporter@quinnemanuel.comjoannacaytas@quinnemanuel.commelanieguzman@quinnemanuel.comcameronkelly@quinnemanuel.com-and-Benjamin I. Finestone (admitted pro hac vice)Sascha N. Rand (admitted pro hac vice)Katherine A. Scherling (admitted pro hac vice)295 5th AvenueNew York, New York 10016Telephone: (212) 849-7000Facsimile: (212) 849-7100Email: benjaminfinestone@quinnemanuel.comsascharand@quinnemanuel.comkatescherling@quinnemanuel.comCOUNSEL FOR THE AD HOC COMMITTEE OFINTRUM AB 2025 NOTEHOLDERSCase 24-90575 Document 296 Filed in TXSB on 01/13/25 Page 5 of 6CERTIFICATE OF SERVICEI, Christopher D. Porter, hereby certify that on the 13th day of January, 2025, a copy ofthe foregoing document has been served via the Electronic Case Filing System for the UnitedStates Bankruptcy Court for the Southern District of Texas./s/ Christopher D. PorterBy: Christopher D. PorterCase 24-90575 Document 296 Filed in TXSB on 01/13/25 Page 6 of 6EXHIBIT ACase 24-90575 Document 296-1 Filed in TXSB on 01/13/25 Page 1 of 31IN THE UNITED STATES BANKRUPTCY COURTFOR THE SOUTHERN DISTRICT OF TEXASHOUSTON DIVISION)In re: ) Chapter 11)Intrum AB, et al.,1 ) Case No. 24-90575 (CML)))Jointly AdministeredDebtors. ))ORDER DENYING MOTION OF THE AD HOCCOMMITTEE OF HOLDERS OF INTRUM AB NOTES DUE 2025TO DISMISS CHAPTER 11 CASES PURSUANT TO 11 U.S.C. § 1112(B) ANDFEDERAL RULE OF BANKRUPTCY PROCEDURE 1017(F)(1)(Related to Docket No. 27)This matter, having come before the Court upon the Motion of the Ad Hoc Committee ofHolders of Intrum AB Notes Due 2025 to Dismiss Chapter 11 Cases Pursuant to 11 U.S.C. §1112(b) and Federal Rule of Bankruptcy Procedure 1017(f)(1) [Docket No. 27] (the “Motion toDismiss”); and this Court having considered the Debtors' Objection to the Motion of the Ad HocCommittee of Holders of Intrum AB Notes Due 2025 to Dismiss Chapter 11 Cases Pursuant to 11U.S.C. § 1112(b) and Federal Rule of Bankruptcy Procedure 1017(f)(1) (the “Objection”) andany other responses or objections to the Motion to Dismiss; and this Court having jurisdiction overthis matter pursuant to 28 U.S.C. § 1334 and the Amended Standing Order; and this Court havingfound that this is a core proceeding pursuant to 28 U.S.C. § 157(b)(2); and this Court having foundthat it may enter a final order consistent with Article III of the United States Constitution; and thisCourt having found that the relief requested in the Objection is in the best interests of the Debtors'1 The Debtors in these Chapter 11 Cases are Intrum AB and Intrum AB of Texas LLC. The Debtors' serviceaddress in these Chapter 11 Cases is 801 Travis Street, STE 2101, #1312, Houston, TX 77002.United States Bankruptcy CourtSouthern District of TexasENTEREDDecember 31, 2024Nathan Ochsner, ClerkCCaassee 2 244-9-900557755 D Dooccuummeennt t2 29662-1 F Filieledd i nin T TXXSSBB o onn 1 021/3/113/2/245 P Paaggee 1 2 o of f2 32estates; and this Court having found that the Debtors' notice of the Objection and opportunity fora hearing on the Motion to Dismiss and Objection were appropriate and no other notice need beprovided; and this Court having reviewed the Motion to Dismiss and Objection and havingheard the statements in support of the relief requested therein at a hearing before this Court; andthis Court having determined that the legal and factual bases set forth in the Objectionestablish just cause for the relief granted herein; and upon all of the proceedings had beforethis Court; and after due deliberation and sufficient cause appearing therefor, it is HEREBYORDERED THAT:1. The Motion to Dismiss is Denied for the reasons stated at the December 31, 2024 hearing.2. This Court retains exclusive jurisdiction and exclusive venue with respect to allmatters arising from or related to the implementation, interpretation, and enforcement of this Order.DAeucegmubste 0r 23,1 2, 0210294CCaassee 2 244-9-900557755 D Dooccuummeennt t2 29662-1 F Filieledd i nin T TXXSSBB o onn 1 021/3/113/2/245 P Paaggee 2 3 o of f2 3EXHIBIT BCase 24-90575 Document 296-2 Filed in TXSB on 01/13/25 Page 1 of 135IN THE UNITED STATES BANKRUPTCY COURTFOR THE SOUTHERN DISTRICT OF TEXASHOUSTON DIVISION)In re: ) Chapter 11)Intrum AB et al.,1 ) Case No. 24-90575 (CML)))(Jointly Administered)Debtors. ))ORDER (I) APPROVINGDISCLOSURE STATEMENT AND(II) CONFIRMING JOINT PREPACKAGED CHAPTER 11PLAN OF INTRUM AB AND ITS AFFILIATEDDEBTOR (FURTHER TECHNICAL MODIFICATIONS)The above-captioned debtors and debtors in possession (collectively, the“Debtors”), having:a. entered into that certain Lock-Up Agreement, dated as of July 10, 2024 (asamended and restated on August 15, 2024, and as further modified,supplemented, or otherwise amended from time to time in accordance with itsterms, the “the Lock-Up Agreement”) and that certain Backstop Agreement,dated as of July 10, 2024, (as amended and restated on November 15, 2024 andas further modified, supplemented, or otherwise amended from time to time inaccordance with its terms), setting out the terms of the backstop commitmentsprovided by the Backstop Providers to backstop the entirety of the issuance ofNew Money Notes (as may be further amended, restated, amended and restated,modified or supplemented from time to time in accordance with the termsthereof, the “Backstop Agreement”) which set forth the terms of a consensualfinancial restructuring of the Debtors;b. commenced, on October 17, 2024, a prepetition solicitation (the “Solicitation”)of votes on the Joint Prepackaged Chapter 11 Plan of Reorganization of IntrumAB and its Debtor Affiliate Pursuant to Chapter 11 of the Bankruptcy Code (asthe same may be further amended, modified and supplemented from time totime, the “Plan”), by causing the transmittal, through their solicitation andballoting agent, Kroll Restructuring Administration LLC (“Kroll”), to theholders of Claims entitled to vote on the Plan of, among other things: (i) the1 The Debtors in these chapter 11 cases are Intrum AB and Intrum AB of Texas LLC. The Debtors' serviceaddress in these chapter 11 cases is 801 Travis Street, STE 2102, #1312, Houston, TX 77002.United States Bankruptcy CourtSouthern District of TexasENTEREDDecember 31, 2024Nathan Ochsner, ClerkCCaassee 2 244-9-900557755 D Dooccuummeennt t2 29663-2 F Filieledd i nin T TXXSSBB o onn 1 021/3/113/2/245 P Paaggee 1 2 o of f1 133452Plan, (ii) the Disclosure Statement for Joint Prepackaged Chapter 11 Plan ofReorganization of Intrum AB and its Debtor Affiliate (as the same may befurther amended, modified and supplemented from time to time, the“Disclosure Statement”), and (iii) the Ballots and Master Ballot to vote on thePlan (the “Ballots”), (iv) the Affidavit of Service of Solicitation Materials[Docket No. 7];c. commenced on November 15, 2024 (the “Petition Date”), these chapter 11 cases(these “Chapter 11 Cases”) by filing voluntary petitions in the United StatesBankruptcy Court for the Southern District of Texas (the “Bankruptcy Court”or the “Court”) for relief under chapter 11 of title 11 of the United States Code(the “Bankruptcy Code”);d. Filed on November 15, 2024, the Affidavit of Service of Solicitation Materials[Docket No. 7] (the “Solicitation Affidavit”);e. Filed, on November 16, 2024 the Joint Prepackaged Chapter 11 Plan ofReorganization of Intrum AB and its Debtor Affiliate Pursuant to Chapter 11of the Bankruptcy Code (Technical Modifications) [Docket No. 16] and theDisclosure Statement for Joint Prepackaged Chapter 11 Plan of Intrum AB andits Debtor Affiliate [Docket No. 17];f. Filed on November 16, 2024, the Declaration of Andrés Rubio in Support of ofthe Debtors' Chapter 11 Petitions and First Day Motions [Docket No. 14] (the“First Day Declaration”);g. Filed on November 17, 2024, the Declaration of Alex Orchowski of KrollRestructuring Administration LLC Regarding the Solicitation of Votes andTabulation of Ballots Case on the Joint Prepackaged Chapter 11 Plan ofReorganization of Intrum AB and its Debtor Affiliate Pursuant to Chapter 11of the Bankruptcy Code [Docket No. 18] (the “Voting Declaration,” andtogether with the Plan, the Disclosure Statement, the Ballots, and theSolicitation Affidavit, the “Solicitation Materials”);h. obtained, on November 19, 2024, the Order(I) Scheduling a Combined Hearingon (A) Adequacy of the Disclosure Statement and (B) Confirmation of the Plan,(II) Approving Solicitation Procedures and Form and Manner of Notice ofCommencement, Combined Hearing, and Objection Deadline, (III) FixingDeadline to Object to Disclosure Statement and Plan, (IV) Conditionally (A)Directing the United States Trustee Not to Convene Section 341 Meeting ofCreditors and (B) Waiving Requirement to File Statements of Financial Affairsand Schedules of Assets and Liabilities, and (V) Granting Related Relief[Docket No. 71] (the “Scheduling Order”), which, among other things: (i)approved the prepetition solicitation and voting procedures, including theConfirmation Schedule (as defined therein); (ii) conditionally approved theDisclosure Statement and its use in the Solicitation; and (iii) scheduled theCombined Hearing on December 16, 2024, at 1:00 p.m. (prevailing CentralCCaassee 2 244-9-900557755 D Dooccuummeennt t2 29663-2 F Filieledd i nin T TXXSSBB o onn 1 021/3/113/2/245 P Paaggee 2 3 o of f1 133453Time) to consider the final approval of the Disclosure Statement and theconfirmation of the Plan (the “Combined Hearing”);i. served, through Kroll, on November 20, 2025, on all known holders of Claimsand Interests, the U.S. Trustee and certain other parties in interest, the Noticeof: (I) Commencement of Chapter 11 Bankruptcy Cases; (II) Hearing on theDisclosure Statement and Confirmation of the Plan, and (III) Certain ObjectionDeadlines (the “Combined Hearing Notice”) as evidence by the Affidavit ofService [Docket No. 160];j. caused, on November 25 and 27, 2024, the Combined Hearing Notice to bepublished in the New York Times (national and international editions) and theFinancial Times (international edition), as evidenced by the Certificate ofPublication [Docket No. 148];k. Filed and served, on December 10, 2024, the Plan Supplement for the Debtors'Joint Prepackaged Chapter 11 Plan of Reorganization [Docket 165];l. Filed on December 10, 2024, the Declaration of Jeffrey Kopa in Support ofConfirmation of the Joint Prepackaged Plan of Reorganization of Intrum ABand its Debtor Affiliate Pursuant to Chapter 11 of the Bankruptcy Code [DocketNo. 155];m. Filed on December 14, 2024, the:i. Debtors' Memorandum of Law in Support of an Order: (I) Approving, on aFinal Basis, Adequacy of the Disclosure Statement; (II) Confirming theJoint Prepackaged Plan of Reorganization; and (III) Granting Related Relief[Docket No. 190] (the “Confirmation Brief”);ii. Declaration of Andrés Rubio in Support of Confirmation of the JointPrepackaged Plan of Reorganization of Intrum AB and its Debtor Affiliate.[Docket No. 189] (the “Confirmation Declaration”); andiii. Joint Prepackaged Chapter 11 Plan of Reorganization of Intrum AB and itsDebtor Affiliate Pursuant to Chapter 11 of the Bankruptcy Code (FurtherTechnical Modifications) [Docket No. 191];n. Filed on December 18, 2024, the Joint Prepackaged Chapter 11 Plan ofReorganization of Intrum AB and its Debtor Affiliate Pursuant to Chapter 11of the Bankruptcy Code (Further Technical Modifications) [Docket No. 223];CCaassee 2 244-9-900557755 D Dooccuummeennt t2 29663-2 F Filieledd i nin T TXXSSBB o onn 1 021/3/113/2/245 P Paaggee 3 4 o of f1 133454WHEREAS, the Court having, among other things:a. set December 12, 2024, at 4:00 p.m. (prevailing Central Time) as the deadlinefor Filing objection to the adequacy of the Disclosure Statement and/orConfirmation2 of the Plan (the “Objection Deadline”);b. held, on December 16, 2024 at 1:00 p.m. (prevailing Central Time) [andcontinuing through December 17, 2024], the Combined Hearing;c. heard the statements, arguments, and any objections made at the CombinedHearing;d. reviewed the Disclosure Statement, the Plan, the Ballots, the Plan Supplement,the Confirmation Brief, the Confirmation Declaration, the SolicitationAffidavit, and the Voting Declaration;e. overruled (i) any and all objections to approval of the Disclosure Statement, thePlan, and Confirmation, except as otherwise stated or indicated on the record,and (ii) all statements and reservations of rights not consensually resolved orwithdrawn, unless otherwise indicated; andf. reviewed and taken judicial notice of all the papers and pleadings Filed(including any objections, statement, joinders, reservations of rights and otherresponses), all orders entered, and all evidence proffered or adduced and allarguments made at the hearings held before the Court during the pendency ofthese cases;NOW, THEREFORE, it appearing to the Bankruptcy Court that notice of theCombined Hearing and the opportunity for any party in interest to object to the DisclosureStatement and the Plan having been adequate and appropriate as to all parties affected or to beaffected by the Plan and the transactions contemplated thereby, and the legal and factual bases setforth in the documents Filed in support of approval of the Disclosure Statement and Confirmationand other evidence presented at the Combined Hearing establish just cause for the relief grantedherein; and after due deliberation thereon and good cause appearing therefor, the BankruptcyCourt makes and issues the following findings of fact and conclusions of law, and orders for thereasons stated on the record at the December 31, 2024 ruling on plan confirmation;2 Capitalized terms used but not otherwise defined herein have meanings given to them in the Plan and/or theDisclosure Statement. The rules of interpretation set forth in Article I.B of the Plan apply to this CombinedOrder.CCaassee 2 244-9-900557755 D Dooccuummeennt t2 29663-2 F Filieledd i nin T TXXSSBB o onn 1 021/3/113/2/245 P Paaggee 4 5 o of f1 133455I. FINDINGS OF FACT AND CONCLUSIONS OF LAWIT IS HEREBY FOUND AND DETERMINED THAT:A. Findings of Fact and Conclusions of Law.1. The findings and conclusions set forth herein and in the record of theCombined Hearing constitute the Bankruptcy Court's findings of fact and conclusions of law underRule 52 of the Federal Rules of Civil Procedure, as made applicable herein by Bankruptcy Rules7052 and 9014. To the extent any of the following conclusions of law constitute findings of fact,or vice versa, they are adopted as such.B. Jurisdiction, Venue, Core Proceeding.2. This Court has jurisdiction over these Chapter 11 Cases pursuant to28 U.S.C. § 1334. Venue of these proceedings and the Chapter 11 Cases in this district is properpursuant to 28 U.S.C. §§ 1408 and 1409. This is a core proceeding pursuant to 28 U.S.C.§ 157(b)(2) and this Court may enter a final order hereon under Article III of the United StatesConstitution.C. Eligibility for Relief.3. The Debtors were and continue to be entities eligible for relief under section109 of the Bankruptcy Code and the Debtors were and continue to be proper proponents of thePlan under section 1121(a) of the Bankruptcy Code.D. Commencement and Joint Administration of the Chapter 11 Cases.4. On the Petition Date, the Debtors commenced the Chapter 11 Cases. OnNovember 18, 2024, the Court entered an order [Docket No. 51] authorizing the jointadministration of the Chapter 11 Case in accordance with Bankruptcy Rule 1015(b). The Debtorshave operated their businesses and managed their properties as debtors in possession pursuant toCCaassee 2 244-9-900557755 D Dooccuummeennt t2 29663-2 F Filieledd i nin T TXXSSBB o onn 1 021/3/113/2/245 P Paaggee 5 6 o of f1 133456sections 1107(a) and 1108 of the Bankruptcy Code. No trustee, examiner, or statutory committeehas been appointed in these Chapter 11 Cases.E. Adequacy of the Disclosure Statement.5. The Disclosure Statement and the exhibits contained therein (i) containssufficient information of a kind necessary to satisfy the disclosure requirements of applicablenonbankruptcy laws, rules and regulations, including the Securities Act; and (ii) contains“adequate information” as such term is defined in section 1125(a)(1) and used in section1126(b)(2) of the Bankruptcy Code, with respect to the Debtors, the Plan and the transactionscontemplated therein. The Filing of the Disclosure Statement satisfied Bankruptcy Rule 3016(b).The injunction, release, and exculpation provisions in the Plan and the Disclosure Statementdescribe, in bold font and with specific and conspicuous language, all acts to be enjoined andidentify the Entities that will be subject to the injunction, thereby satisfying Bankruptcy Rule3016(c).F. Solicitation.6. As described in and evidenced by the Voting Declaration, the Solicitationand the transmittal and service of the Solicitation Materials were: (i) timely, adequate, appropriate,and sufficient under the circumstances; and (ii) in compliance with sections 1125(g) and 1126(b)of the Bankruptcy Code, Bankruptcy Rules 3017 and 3018, the applicable Local Bankruptcy Rules,the Scheduling Order and all applicable nonbankruptcy rules, laws, and regulations applicable tothe Solicitation, including the registration requirements under the Securities Act. The SolicitationMaterials, including the Ballots and the Opt Out Form (as defined below), adequately informedthe holders of Claims entitled to vote on the Plan of the procedures and deadline for completingand submitting the Ballots.CCaassee 2 244-9-900557755 D Dooccuummeennt t2 29663-2 F Filieledd i nin T TXXSSBB o onn 1 021/3/113/2/245 P Paaggee 6 7 o of f1 1334577. The Debtors served the Combined Hearing Notice on the entire creditormatrix and served the Opt Out Form on all Non-Voting Classes. The Combined Hearing Noticeadequately informed Holders of Claims or Interests of critical information regarding voting on (ifapplicable) and objecting to the Plan, including deadlines and the inclusion of release, exculpation,and injunction provisions in the Plan, and adequately summarized the terms of the Third-PartyRelease. Further, because the form enabling stakeholders to opt out of the Third-Party Release (the“Opt Out Form”) was included in both the Ballots and the Opt Out Form, every known stakeholder,including unimpaired creditors was provided with the means by which the stakeholders could optout of the Third-Party Release. No further notice is required. The period for voting on the Planprovided a reasonable and sufficient period of time and the manner of such solicitation was anappropriate process allowing for such holders to make an informed decision.G. Tabulation.8. As described in and evidenced by the Voting Declaration, (i) the holders ofClaims in Class 3 (RCF Claims) and Class 5 (Notes Claims) are Impaired under the Plan(collectively, the “Voting Classes”) and have voted to accept the Plan in the numbers and amountsrequired by section 1126 of the Bankruptcy Code, and (ii) no Class that was entitled to vote on thePlan voted to reject the Plan. All procedures used to tabulate the votes on the Plan were in goodfaith, fair, reasonable, and conducted in accordance with the applicable provisions of theBankruptcy Code, the Bankruptcy Rules, the Local Rules, the Disclosure Statement, theScheduling Order, and all other applicable nonbankruptcy laws, rules, and regulations.H. Plan Supplement.9. On December 10, 2024, the Debtors Filed the Plan Supplement with theCourt. The Plan Supplement (including as subsequently modified, supplemented, or otherwiseCCaassee 2 244-9-900557755 D Dooccuummeennt t2 29663-2 F Filieledd i nin T TXXSSBB o onn 1 021/3/113/2/245 P Paaggee 7 8 o of f1 133458amended pursuant to a filing with the Court), complies with the terms of the Plan, and the Debtorsprovided good and proper notice of the filing in accordance with the Bankruptcy Code, theBankruptcy Rules, the Scheduling Order, and the facts and circumstances of the Chapter 11 Cases.All documents included in the Plan Supplement are integral to, part of, and incorporated byreference into the Plan. No other or further notice is or will be required with respect to the PlanSupplement. Subject to the terms of the Plan and the Lock-Up Agreement, and only consistenttherewith, the Debtors reserve the right to alter, amend, update, or modify the Plan Supplementand any of the documents contained therein or related thereto, in accordance with the Plan, on orbefore the Effective Date.I. Modifications to the Plan.10. Pursuant to section 1127 of the Bankruptcy Code, the modifications to thePlan described or set forth in this Combined Order constitute technical or clarifying changes,changes with respect to particular Claims by agreement with holders of such Claims, ormodifications that do not otherwise materially and adversely affect or change the treatment of anyother Claim or Interest under the Plan. These modifications are consistent with the disclosurespreviously made pursuant to the Disclosure Statement and Solicitation Materials, and notice ofthese modifications was adequate and appropriate under the facts and circumstances of the Chapter11 Cases. In accordance with Bankruptcy Rule 3019, these modifications do not require additionaldisclosure under section 1125 of the Bankruptcy Code or the resolicitation of votes under section1126 of the Bankruptcy Code, and they do not require that holders of Claims or Interests beafforded an opportunity to change previously cast acceptances or rejections of the Plan.Accordingly, the Plan is properly before this Court and all votes cast with respect to the Plan priorto such modification shall be binding and shall apply with respect to the Plan.CCaassee 2 244-9-900557755 D Dooccuummeennt t2 29663-2 F Filieledd i nin T TXXSSBB o onn 1 021/3/113/2/245 P Paaggee 8 9 o of f1 133459J. Objections Overruled.11. Any resolution or disposition of objections to Confirmation explained orotherwise ruled upon by the Court on the record at the Confirmation Hearing is herebyincorporated by reference. All unresolved objections, statements, joinders, informal objections,and reservations of rights are hereby overruled on the merits.K. Burden of Proof.12. The Debtors, as proponents of the Plan, have met their burden of provingthe elements of sections 1129(a) and 1129(b) of the Bankruptcy Code by a preponderance of theevidence, the applicable evidentiary standard for Confirmation. Further, the Debtors have proventhe elements of sections 1129(a) and 1129(b) by clear and convincing evidence. Each witness whotestified on behalf of the Debtors in connection with the Confirmation Hearing was credible,reliable, and qualified to testify as to the topics addressed in his testimony.L. Compliance with the Requirements of Section 1129 of the BankruptcyCode.13. The Plan complies with all applicable provisions of section 1129 of theBankruptcy Code as follows:a. Section 1129(a)(1) – Compliance of the Plan with Applicable Provisions of theBankruptcy Code.14. The Plan complies with all applicable provisions of the Bankruptcy Code,including sections 1122 and 1123, as required by section 1129(a)(1) of the Bankruptcy Code.i. Section 1122 and 1123(a)(1) – Proper Classification.15. The classification of Claims and Interests under the Plan is proper under theBankruptcy Code. In accordance with sections 1122(a) and 1123(a)(1) of the Bankruptcy Code,Article III of the Plan provides for the separate classification of Claims and Interests at each Debtorinto Classes, based on differences in the legal nature or priority of such Claims and Interests (otherCaCsaes e2 42-49-09507557 5 D oDcoucmumenetn 2t 9266-32 FFiilleedd iinn TTXXSSBB oonn 1021//3113//2245 PPaaggee 91 0o fo 1f 3143510than Administrative Claims, Professional Fee Claims, and Priority Tax Claims, which areaddressed in Article II of the Plan and Unimpaired, and are not required to be designated asseparate Classes in accordance with section 1123(a)(1) of the Bankruptcy Code). Valid business,factual, and legal reasons exist for the separate classification of the various Classes of Claims andInterests created under the Plan, the classifications were not implemented for any improperpurpose, and the creation of such Classes does not unfairly discriminate between or among holdersof Claims or Interests.16. In accordance with section 1122(a) of the Bankruptcy Code, each Class ofClaims or Interests contains only Claims or Interests substantially similar to the other Claims orInterests within that Class. Accordingly, the Plan satisfies the requirements of sections 1122(a),1122(b), and 1123(a)(1) of the Bankruptcy Codeii. Section 1123(a)(2) – Specifications of Unimpaired Classes.17. Article III of the Plan specifies that Claims and Interests in the classesdeemed to accept the Plan are Unimpaired under the Plan. Holders of Intercompany Claims andIntercompany Interests are either Unimpaired and conclusively presumed to have accepted thePlan, or are Impaired and deemed to reject (the “Deemed Rejecting Classes”) the Plan, and, ineither event, are not entitled to vote to accept or reject the Plan. In addition, Article II of the Planspecifies that Administrative Claims and Priority Tax Claims are Unimpaired, although the Plandoes not classify these Claims. Accordingly, the Plan satisfies the requirements of section1123(a)(2) of the Bankruptcy Code.CCaassee 2 244-9-900557755 D Dooccuummeennt t2 29663-2 F Fileiledd i nin T TXXSSBB o onn 1 021/3/113/2/245 P Paaggee 1 101 o of f1 1334511iii. Section 1123(a)(3) – Specification of Treatment of Voting Classes18. Article III.B of the Plan specifies the treatment of each Voting Class underthe Plan – namely, Class 3 and Class 5. Accordingly, the Plan satisfies the requirements of section1123(a)(3) of the Bankruptcy Code.iv. Section 1123(a)(4) – No Discrimination.19. Article III of the Plan provides the same treatment to each Claim or Interestin any particular Class, as the case may be, unless the holder of a particular Claim or Interest hasagreed to a less favorable treatment with respect to such Claim or Interest. Accordingly, the Plansatisfies the requirements of section 1123(a)(4) of the Bankruptcy Code.v. Section 1123(a)(5) – Adequate Means for Plan Implementation.20. The Plan and the various documents included in the Plan Supplementprovide adequate and proper means for the Plan's execution and implementation, including: (a)the general settlement of Claims and Interests; (b) the restructuring of the Debtors' balance sheetand other financial transactions provided for by the Plan; (c) the consummation of the transactionscontemplated by the Plan, the Lock-Up Agreement, the Restructuring Implementation Deed andthe Agreed Steps Plan and other documents Filed as part of the Plan Supplement; (d) the issuanceof Exchange Notes, the New Money Notes, and the Noteholder Ordinary Shares pursuant to thePlan; (e) the amendment of the Intercreditor Agreement; (f) the amendment of the FacilityAgreement; (g) the amendment of the Senior Secured Term Loan Agreement; (h) theconsummation of the Rights Offering in accordance with the Plan, Rights Offering Documentsand the Lock-Up Agreement; (i) the granting of all Liens and security interests granted orconfirmed (as applicable) pursuant to, or in connection with, the Facility Agreement, the ExchangeNotes Indenture, the New Money Notes Indenture, the amended Intercreditor Agreement and theCCaassee 2 244-9-900557755 D Dooccuummeennt t2 29663-2 F Fileiledd i nin T TXXSSBB o onn 1 021/3/113/2/245 P Paaggee 1 112 o of f1 1334512Senior Secured Term Loan Agreement pursuant to the New Security Documents (including anyLiens and security interests granted or confirmed (as applicable) on the Reorganized Debtors'assets); (j) the vesting of the assets of the Debtors' Estates in the Reorganized Debtors; (k) theconsummation of the corporate reorganization contemplated by the Plan, the Lock-Up Agreement,the Agreed Steps Plan and the Master Reorganization Agreement (as defined in the RestructuringImplementation Deed); and (l) the execution, delivery, filing, or recording of all contracts,instruments, releases, and other agreements or documents in furtherance of the Plan. Accordingly,the Plan satisfies the requirements of section 1123(a)(5) of the Bankruptcy Codevi. Section 1123(a)(6) – Non-Voting Equity Securities.21. The Company's organizational documents in accordance with the SwedishCompanies Act, Ch. 4, Sec 5 and the Plan prohibit the issuance of non-voting securities as of theEffective Date to the extent required to comply with section 1123(a)(6) of the Bankruptcy Code.Accordingly, the Plan satisfies the requirements of section 1123(a)(6) of the Bankruptcy Code.vii. Section 1123(a)(7) – Directors, Officers, and Trustees.22. The manner of selection of any officer, director, or trustee (or any successorto and such officer, director, or trustee) of the Reorganized Debtors will be determined inaccordance with the existing organizational documents, which is consistent with the interests ofcreditors and equity holders and with public policy. Accordingly, the Plan satisfies therequirements of section 1123(a)(7) of the Bankruptcy Code.b. Section 1123(b) – Discretionary Contents of the Plan23. The Plan contains various provisions that may be construed as discretionarybut not necessary for Confirmation under the Bankruptcy Code. Any such discretionary provisionCCaassee 2 244-9-900557755 D Dooccuummeennt t2 29663-2 F Fileiledd i nin T TXXSSBB o onn 1 021/3/113/2/245 P Paaggee 1 123 o of f1 1334513complies with section 1123(b) of the Bankruptcy Code and is not inconsistent with the applicableprovisions of the Bankruptcy Code. Thus, the Plan satisfies section 1123(b).i. Section 1123(b)(1) – Impairment/Unimpairment of Any Class of Claims orInterests24. Article III of the Plan impairs or leaves unimpaired, as the case may be,each Class of Claims or Interests, as contemplated by section 1123(b)(1) of the Bankruptcy Code.ii. Section 1123(b)(2) – Assumption and Rejection of Executory Contracts andUnexpired Leases25. Article V of the Plan provides for the assumption of the Debtors' ExecutoryContracts and Unexpired Leases as of the Effective Date unless such Executory Contract orUnexpired Lease: (a) is identified on the Rejected Executory Contract and Unexpired Lease List;(b) has been previously rejected by a Final Order; (c) is the subject of a motion to reject ExecutoryContracts or Unexpired Leases that is pending on the Confirmation Date; or (4) is subject to amotion to reject an Executory Contract or Unexpired Lease pursuant to which the requestedeffective date of such rejection is after the Effective Date. Thus, the Plan satisfies section1123(b)(2).iii. Compromise and Settlement26. In accordance with section 1123(b)(3)(A) of the Bankruptcy Code andBankruptcy Rule 9019, and in consideration for the distributions and other benefits provided underthe Plan, the provisions of the Plan constitute a good-faith compromise of all Claims, Interests,and controversies relating to the contractual, legal, and subordination rights that all holders ofClaims or Interests may have with respect to any Allowed Claim or Interest or any distribution tobe made on account of such Allowed Claim or Interest. Such compromise and settlement is theproduct of extensive arm's-length, good faith negotiations that, in addition to the Plan, resulted inCCaassee 2 244-9-900557755 D Dooccuummeennt t2 29663-2 F Fileiledd i nin T TXXSSBB o onn 1 021/3/113/2/245 P Paaggee 1 134 o of f1 1334514the execution of the Lock-Up Agreement, which represents a fair and reasonable compromise ofall Claims, Interests, and controversies and entry into which represented a sound exercise of theDebtors' business judgment. Such compromise and settlement is fair, equitable, and reasonableand in the best interests of the Debtors and their Estates.27. The releases of the Debtors' directors and officers are an integral componentof the settlements and compromises embodied in the Plan. The Debtors' directors and officers: (a)made a substantial and valuable contribution to the Debtors' restructuring, including extensive preandpost-Petition Date negotiations with stakeholder groups, and ensured the uninterruptedoperation of the Debtors' businesses during the Chapter 11 Cases; (b) invested significant timeand effort to make the restructuring a success and maximize the value of the Debtors' businessesin a challenging operating environment; (c) attended and, in certain instances, testified atdepositions and Court hearings; (d) attended and participated in numerous stakeholder meetings,management meetings, and board meetings related to the restructuring; (e) are entitled toindemnification from the Debtors under applicable non-bankruptcy law, organizationaldocuments, and agreements; (f) invested significant time and effort in the preparation of the Lock-Up Agreement, the Plan, Disclosure Statement, all supporting analyses, and the numerous otherpleadings Filed in the Chapter 11 Cases, thereby ensuring the smooth administration of the Chapter11 Cases; and (g) are entitled to all other benefits under any employment contracts existing as ofthe Petition Date. Litigation by the Debtors or other Releasing Parties against the Debtors'directors and officers would be a distraction to the Debtors' business and restructuring and woulddecrease rather than increase the value of the estates. The releases of the Debtors' directors andofficers contained in the Plan have the consent of the Debtors and the Releasing Parties and are inthe best interests of the estates.CCaassee 2 244-9-900557755 D Dooccuummeennt t2 29663-2 F Fileiledd i nin T TXXSSBB o onn 1 021/3/113/2/245 P Paaggee 1 145 o of f1 1334515iv. Debtor Release28. The releases of claims and Causes of Action by the Debtors, ReorganizedDebtors, and their Estates described in Article VIII.C of the Plan in accordance with section1123(b) of the Bankruptcy Code (the “Debtor Release”) represent a valid exercise of the Debtors'business judgment under Bankruptcy Rule 9019. The Debtors' or the Reorganized Debtors' pursuitof any such claims against the Released Parties is not in the best interests of the Estates' variousconstituencies because the costs involved would outweigh any potential benefit from pursuingsuch claims. The Debtor Release is fair and equitable and complies with the absolute priority rule.29. The Debtor Release is (a) an integral part of the Plan, and a component ofthe comprehensive settlement implemented under the Plan; (b) in exchange for the good andvaluable consideration provided by the Released Parties; (c) a good faith settlement andcompromise of the claims and Causes of Action released by the Debtor Release; (d) materiallybeneficial to, and in the best interests of, the Debtors, their Estates, and their stakeholders, and isimportant to the overall objectives of the Plan to finally resolve certain Claims among or againstcertain parties in interest in the Chapter 11 Cases; (e) fair, equitable, and reasonable; (f) given andmade after due notice and opportunity for hearing; and (g) a bar to any Debtor asserting any claimor Cause of Action released by the Debtor Release against any of the Released Parties. Theprobability of success in litigation with respect to the released claims and Causes of Action, whenweighed against the costs, supports the Debtor Release. With respect to each of these potentialCauses of Action, the parties could assert colorable defenses and the probability of success isuncertain. The Debtors' or the Reorganized Debtors' pursuit of any such claims or Causes ofAction against the Released Parties is not in the best interests of the Estates or the Debtors' variousCCaassee 2 244-9-900557755 D Dooccuummeennt t2 29663-2 F Fileiledd i nin T TXXSSBB o onn 1 021/3/113/2/245 P Paaggee 1 156 o of f1 1334516constituencies because the costs involved would likely outweigh any potential benefit frompursuing such claims or Causes of Action30. Holders of Claims and Interests entitled to vote have overwhelmingly votedin favor of the Plan, including the Debtor Release. The Plan, including the Debtor Release, wasnegotiated before and after the Petition Date by sophisticated parties represented by able counseland advisors, including the Consenting Creditors. The Debtor Release is therefore the result of ahard fought and arm's-length negotiation process conducted in good faith.31. The Debtor Release appropriately offers protection to parties thatparticipated in the Debtors' restructuring process, including the Consenting Creditors, whoseparticipation in the Chapter 11 Cases is critical to the Debtors' successful emergence frombankruptcy. Specifically, the Released Parties, including the Consenting Creditors, madesignificant concessions and contributions to the Chapter 11 Cases, including, entering into theLock-Up Agreement and related agreements, supporting the Plan and the Chapter 11 Cases, andwaiving or agreeing to impair substantial rights and Claims against the Debtors under the Plan (aspart of the compromises composing the settlement underlying the revised Plan) in order tofacilitate a consensual reorganization and the Debtors' emergence from chapter 11. The DebtorRelease for the Debtors' directors and officers is appropriate because the Debtors' directors andofficers share an identity of interest with the Debtors and, as previously stated, supported and madesubstantial contributions to the success of the Plan, the Chapter 11 Cases, and operation of theDebtors' business during the Chapter 11 Cases, actively participated in meetings, negotiations, andimplementation during the Chapter 11 Cases, and have provided other valuable consideration tothe Debtors to facilitate the Debtors' successful reorganization and continued operation.CCaassee 2 244-9-900557755 D Dooccuummeennt t2 29663-2 F Fileiledd i nin T TXXSSBB o onn 1 021/3/113/2/245 P Paaggee 1 167 o of f1 133451732. The scope of the Debtor Release is appropriately tailored under the factsand circumstances of the Chapter 11 Cases. In light of, among other things, the value provided bythe Released Parties to the Debtors' Estates and the critical nature of the Debtor Release to thePlan, the Debtor Release is appropriate.v. Release by Holders of Claims and Interests33. The release by the Releasing Parties (the “Third-Party Release”), set forthin Article VIII.D of the Plan, is an essential provision of the Plan. The Third-Party Release is: (a)consensual as to those Releasing Parties that did not specifically and timely object or properly optout from the Third-Party Release; (b) within the jurisdiction of the Bankruptcy Court pursuant to28 U.S.C. § 1334; (c) in exchange for the good and valuable consideration provided by theReleased Parties; (d) a good faith settlement and compromise of the claims and Causes of Actionreleased by the Third-Party Release; (e) materially beneficial to, and in the best interests of, theDebtors, their Estates, and their stakeholders, and is important to the overall objectives of the Planto finally resolve certain Claims among or against certain parties in interest in the Chapter 11Cases; (f) fair, equitable, and reasonable; (g) given and made after due notice and opportunity forhearing; (h) appropriately narrow in scope given that it expressly excludes, among other things,any Cause of Action that is judicially determined by a Final Order to have constituted actual fraud,willful misconduct, or gross negligence; (i) a bar to any of the Releasing Parties asserting anyclaim or Cause of Action released by the Third-Party Release against any of the Released Parties;and (j) consistent with sections 105, 524, 1123, 1129, and 1141 and other applicable provisions ofthe Bankruptcy Code.34. The Third-Party Release is an integral part of the agreement embodied inthe Plan among the relevant parties in interest. Like the Debtor Release, the Third-Party ReleaseCCaassee 2 244-9-900557755 D Dooccuummeennt t2 29663-2 F Fileiledd i nin T TXXSSBB o onn 1 021/3/113/2/245 P Paaggee 1 178 o of f1 1334518facilitated participation in both the Debtors' Plan and the chapter 11 process generally. The Third-Party Release is instrumental to the Plan and was critical in incentivizing parties to support thePlan and preventing significant and time-consuming litigation regarding the parties' respectiverights and interests. The Third-Party Release was a core negotiation point in connection with thePlan and instrumental in developing the Plan that maximized value for all of the Debtors'stakeholders and kept the Debtors intact as a going concern. As such, the Third-Party Releaseappropriately offers certain protections to parties who constructively participated in the Debtors'restructuring process—including the Consenting Creditors (as set forth above)—by, among otherthings, facilitating the negotiation and consummation of the Plan, supporting the Plan and, in thecase of the Backstop Providers, committing to provide new capital to facilitate the Debtors'emergence from chapter 11. Specifically, the Notes Ad Hoc Group proposed and negotiated thepari passu transaction that is the basis of the restructuring proposed under the Plan and provideda much-needed deleveraging to the Debtors' business while taking a discount on their Claims (inexchange for other consideration).35. Furthermore, the Third-Party Release is consensual as to all parties ininterest, including all Releasing Parties, and such parties in interest were provided notice of thechapter 11 proceedings, the Plan, the deadline to object to confirmation of the Plan, and theCombined Hearing and were properly informed that all holders of Claims against or Interests inthe Debtors that did not file an objection with the Court in the Chapter 11 Cases that included anexpress objection to the inclusion of such holder as a Releasing Party under the provisionscontained in Article VIII of the Plan would be deemed to have expressly, unconditionally,generally, individually, and collectively consented to the release and discharge of all claims andCauses of Action against the Debtors and the Released Parties. Additionally, the release provisionsCCaassee 2 244-9-900557755 D Dooccuummeennt t2 29663-2 F Fileiledd i nin T TXXSSBB o onn 1 021/3/113/2/245 P Paaggee 1 189 o of f1 1334519of the Plan were conspicuous, emphasized with boldface type in the Plan, the DisclosureStatement, the Ballots, and the applicable notices. Except as set forth in the Plan, all ReleasingParties were properly informed that unless they (a) checked the “opt out” box on the applicableBallot or opt-out form and returned the same in advance of the Voting Deadline, as applicable, or(b) timely Filed an objection to the releases contained in the Plan that was not resolved beforeentry of this Confirmation Order, they would be deemed to have expressly consented to the releaseof all Claims and Causes of Action against the Released Parties.36. The Ballots sent to all holders of Claims and Interests entitled to vote, aswell as the notice of the Combined Hearing sent to all known parties in interest (including thosenot entitled to vote on the Plan), unambiguously provided in bold letters that the Third-PartyRelease was contained in the Plan.37. The scope of the Third-Party Release is appropriately tailored under thefacts and circumstances of the Chapter 11 Cases, and parties in interest received due and adequatenotice of the Third-Party Release. Among other things, the Plan provides appropriate and specificdisclosure with respect to the claims and Causes of Action that are subject to the Third-PartyRelease, and no other disclosure is necessary. The Debtors, as evidenced by the VotingDeclaration and Certificate of Publication, including by providing actual notice to all knownparties in interest, including all known holders of Claims against, and Interests in, any Debtor andpublishing notice in international and national publications for the benefit of unknown parties ininterest, provided sufficient notice of the Third-Party Release, and no further or other notice isnecessary. The Third-Party Release is designed to provide finality for the Debtors, theReorganized Debtors and the Released Parties regarding the parties' respective obligations underthe Plan. For the avoidance of doubt, and notwithstanding anything to the contrary, anyparty who timely opted-out of the Third-Party Release is not bound by the Third-PartyRelease.CCaassee 2 244-9-900557755 D Dooccuummeennt t2 29663-2 F Fileiledd i nin T TXXSSBB o onn 1 021/3/113/2/245 P Paaggee 1 290 o of f1 133452038. The Third-Party Release is specific in language, integral to the Plan, andgiven for substantial consideration. The Releasing Parties were given due and adequate notice ofthe Third-Party Release, and thus the Third-Party Release is consensual under controllingprecedent as to those Releasing Parties that did not specifically and timely object. In light of,among other things, the value provided by the Released Parties to the Debtors' Estates and theconsensual and critical nature of the Third-Party Release to the Plan, the Third-Party Release isappropriatevi. Exculpation.39. The exculpation described in Article VIII.E of the Plan (the “Exculpation”)is appropriate under applicable law, including In re Highland Capital Mgmt., L.P., 48 F. 4th 419(5th Cir. 2022), because it was supported by proper evidence, proposed in good faith, wasformulated following extensive good-faith, arm's-length negotiations with key constituents, and isappropriately limited in scope.40. No Entity or Person may commence or continue any action, employ anyprocess, or take any other act to pursue, collect, recover or offset any Claim, Interest, debt,obligation, or Cause of Action relating or reasonably likely to relate to any act or commission inconnection with, relating to, or arising out of a Covered Matter (including one that alleges theactual fraud, gross negligence, or willful misconduct of a Covered Entity), unless expresslyauthorized by the Bankruptcy Court after (1) it determines, after a notice and a hearing, such Claim,Interest, debt, obligation, or Cause of Action is colorable and (2) it specifically authorizes suchEntity or Person to bring such Claim or Cause of Action. The Bankruptcy Court shall have soleand exclusive jurisdiction to determine whether any such Claim, Interest, debt, obligation or Causeof Action is colorable and, only to the extent legally permissible and as provided for in Article XI,CCaassee 2 244-9-900557755 D Dooccuummeennt t2 29663-2 F Fileiledd i nin T TXXSSBB o onn 1 021/3/113/2/245 P Paaggee 2 201 o of f1 1334521shall have jurisdiction to adjudicate such underlying colorable Claim, Interest, debt, obligation, orCause of Action.vii. Injunction.41. The injunction provisions set forth in Article VIII.F of the Plan are essentialto the Plan and are necessary to implement the Plan and to preserve and enforce the discharge,Debtor Release, the Third-Party Release, and the Exculpation provisions in Article VIII of thePlan. The injunction provisions are appropriately tailored to achieve those purposes.viii. Preservation of Claims and Causes of Action.42. Article IV.L of the Plan appropriately provides for the preservation by theDebtors of certain Causes of Action in accordance with section 1123(b) of the Bankruptcy Code.Causes of Action not released by the Debtors or exculpated under the Plan will be retained by theReorganized Debtors as provided by the Plan. The Plan is sufficiently specific with respect to theCauses of Action to be retained by the Debtors, and the Plan and Plan Supplement providemeaningful disclosure with respect to the potential Causes of Action that the Debtors may retain,and all parties in interest received adequate notice with respect to such retained Causes of Action.The provisions regarding Causes of Action in the Plan are appropriate and in the best interests ofthe Debtors, their respective Estates, and holders of Claims or Interests. For the avoidance of anydoubt, Causes of Action released or exculpated under the Plan will not be retained by theReorganized Debtors.c. Section 1123(d) – Cure of Defaults43. Article V.D of the Plan provides for the satisfaction of Cure Claimsassociated with each Executory Contract and Unexpired Lease to be assumed in accordance withsection 365(b)(1) of the Bankruptcy Code. Any monetary defaults under each assumed ExecutoryCCaassee 2 244-9-900557755 D Dooccuummeennt t2 29663-2 F Fileiledd i nin T TXXSSBB o onn 1 021/3/113/2/245 P Paaggee 2 212 o of f1 1334522Contract or Unexpired Lease shall be satisfied, pursuant to section 365(b)(1) of the BankruptcyCode, by payment of the default amount in Cash on the Effective Date, subject to the limitationsdescribed in Article V.D of the Plan, or on such other terms as the parties to such ExecutoryContracts or Unexpired Leases may otherwise agree. Any Disputed Cure Amounts will bedetermined in accordance with the procedures set forth in Article V.D of the Plan, and applicablebankruptcy and nonbankruptcy law. As such, the Plan provides that the Debtors will Cure, orprovide adequate assurance that the Debtors will promptly Cure, defaults with respect to assumedExecutory Contracts and Unexpired Leases in accordance with section 365(b)(1) of theBankruptcy Code. Thus, the Plan complies with section 1123(d) of the Bankruptcy Code.d. Section 1129(a)(2) – Compliance of the Debtors and Others with the ApplicableProvisions of the Bankruptcy Code.44. The Debtors, as proponents of the Plan, have complied with all applicableprovisions of the Bankruptcy Code as required by section 1129(a)(2) of the Bankruptcy Code,including sections 1122, 1123, 1124, 1125, 1126, and 1128, and Bankruptcy Rules 3017, 3018,and 3019.e. Section 1129(a)(3) – Proposal of Plan in Good Faith.45. The Debtors have proposed the Plan in good faith, in accordance with theBankruptcy Code requirements, and not by any means forbidden by law. In determining that thePlan has been proposed in good faith, the Court has examined the totality of the circumstancesfiling of the Chapter 11 Cases, including the formation of Intrum AB of Texas LLC (“IntrumTexas”), the Plan itself, and the process leading to its formulation. The Debtors' good faith isevident from the facts and record of the Chapter 11 Cases, the Disclosure Statement, and the recordof the Combined Hearing and other proceedings held in the Chapter 11 CasesCCaassee 2 244-9-900557755 D Dooccuummeennt t2 29663-2 F Fileiledd i nin T TXXSSBB o onn 1 021/3/113/2/245 P Paaggee 2 223 o of f1 133452346. The Plan (including the Plan Supplement and all other documents necessaryto effectuate the Plan) is the product of good faith, arm's-length negotiations by and among theDebtors, the Debtors' directors and officers and the Debtors' key stakeholders, including theConsenting Creditors and each of their respective professionals. The Plan itself and the processleading to its formulation provide independent evidence of the Debtors' and such other parties'good faith, serve the public interest, and assure fair treatment of holders of Claims or Interests.Consistent with the overriding purpose of chapter 11, the Debtors Filed the Chapter 11 Cases withthe belief that the Debtors were in need of reorganization and the Plan was negotiated and proposedwith the intention of accomplishing a successful reorganization and maximizing stakeholder value,and for no ulterior purpose. Accordingly, the requirements of section 1129(a)(3) of the BankruptcyCode are satisfied.f. Section 1129(a)(4) – Court Approval of Certain Payments as Reasonable.47. Any payment made or to be made by the Debtors, or by a person issuingsecurities or acquiring property under the Plan, for services or costs and expenses in connectionwith the Chapter 11 Cases, or in connection with the Plan and incident to the Chapter 11 Cases,has been approved by, or is subject to the approval of, the Court as reasonable. Accordingly, thePlan satisfies the requirements of section 1129(a)(4).g. Section 1129(a)(5)—Disclosure of Directors and Officers and Consistency with theInterests of Creditors and Public Policy.48. The identities of or process for appointment of the Reorganized Debtors'directors and officers proposed to serve after the Effective Date were disclosed in the PlanSupplement in advance of the Combined Hearing. Accordingly, the Debtors have satisfied therequirements of section 1129(a)(5) of the Bankruptcy Code.CCaassee 2 244-9-900557755 D Dooccuummeennt t2 29663-2 F Fileiledd i nin T TXXSSBB o onn 1 021/3/113/2/245 P Paaggee 2 234 o of f1 1334524h. Section 1129(a)(6)—Rate Changes.49. The Plan does not contain any rate changes subject to the jurisdiction of anygovernmental regulatory commission and therefore will not require governmental regulatoryapproval. Therefore, section 1129(a)(6) of the Bankruptcy Code does not apply to the Plan.i. Section 1129(a)(7)—Best Interests of Holders of Claims and Interests.50. The liquidation analysis attached as Exhibit D to the Disclosure Statementand the other evidence in support of the Plan that was proffered or adduced at the CombinedHearing, and the facts and circumstances of the Chapter 11 Cases are (a) reasonable, persuasive,credible, and accurate as of the dates such analysis or evidence was prepared, presented orproffered; (b) utilize reasonable and appropriate methodologies and assumptions; (c) have not beencontroverted by other evidence; and (d) establish that each holder of Allowed Claims or Interestsin each Class will recover as much or more value under the Plan on account of such Claim orInterest, as of the Effective Date, than the amount such holder would receive if the Debtors wereliquidated on the Effective Date under chapter 7 of the Bankruptcy Code or has accepted the Plan.As a result, the Debtors have demonstrated that the Plan is in the best interests of their creditorsand equity holders and the requirements of section 1129(a)(7) of the Bankruptcy Code are satisfied.j. Section 1129(a)(8)—Conclusive Presumption of Acceptance by UnimpairedClasses; Acceptance of the Plan by Certain Voting Classes.51. The classes deemed to accept the Plan are Unimpaired under the Plan andare deemed to have accepted the Plan pursuant to section 1126(f) of the Bankruptcy Code. EachVoting Class voted to accept the Plan. For the avoidance of doubt, however, even if section1129(a)(8) has not been satisfied with respect to all of the Debtors, the Plan is confirmable becausethe Plan does not discriminate unfairly and is fair and equitable with respect to the Voting Classesand thus satisfies section 1129(b) of the Bankruptcy Code with respect to such Classes as describedCCaassee 2 244-9-900557755 D Dooccuummeennt t2 29663-2 F Fileiledd i nin T TXXSSBB o onn 1 021/3/113/2/245 P Paaggee 2 245 o of f1 1334525further below. As a result, the requirements of section 1129(b) of the Bankruptcy Code are alsosatisfied.k. Section 1129(a)(9)—Treatment of Claims Entitled to Priority Pursuant to Section507(a) of the Bankruptcy Code.52. The treatment of Administrative Claims, Professional Fee Claims, andPriority Tax Claims under Article II of the Plan satisfies the requirements of, and complies in allrespects with, section 1129(a)(9) of the Bankruptcy Code.l. Section 1129(a)(10)—Acceptance by at Least One Voting Class.53. As set forth in the Voting Declaration, all Voting Classes overwhelminglyvoted to accept the Plan. As such, there is at least one Voting Class that has accepted the Plan,determined without including any acceptance of the Plan by any insider (as defined by theBankruptcy Code), for each Debtor. Accordingly, the requirements of section 1129(a)(10) of theBankruptcy Code are satisfied.m. Section 1129(a)(11)—Feasibility of the Plan.54. The Plan satisfies section 1129(a)(11) of the Bankruptcy Code. Thefinancial projections attached to the Disclosure Statement as Exhibit D and the other evidencesupporting the Plan proffered or adduced by the Debtors at or before the Combined Hearing: (a)is reasonable, persuasive, credible, and accurate as of the dates such evidence was prepared,presented, or proffered; (b) utilize reasonable and appropriate methodologies and assumptions; (c)has not been controverted by other persuasive evidence; (d) establishes that the Plan is feasibleand Confirmation of the Plan is not likely to be followed by liquidation or the need for furtherfinancial reorganization; (e) establishes that the Debtors will have sufficient funds available tomeet their obligations under the Plan and in the ordinary course of business—including sufficientamounts of Cash to reasonably ensure payment of Allowed Claims that will receive CashCCaassee 2 244-9-900557755 D Dooccuummeennt t2 29663-2 F Fileiledd i nin T TXXSSBB o onn 1 021/3/113/2/245 P Paaggee 2 256 o of f1 1334526distributions pursuant to the terms of the Plan and other Cash payments required under the Plan;and (f) establishes that the Debtors or the Reorganized Debtors, as applicable, will have thefinancial wherewithal to pay any Claims that accrue, become payable, or are allowed by FinalOrder following the Effective Date. Accordingly, the Plan satisfies the requirements of section1129(a)(11) of the Bankruptcy Code.n. Section 1129(a)(12)—Payment of Statutory Fees.55. Article XII.C of the Plan provides that all fees payable pursuant to section1930(a) of the Judicial Code, as determined by the Court at the Confirmation Hearing inaccordance with section 1128 of the Bankruptcy Code, will be paid by each of the applicableReorganized Debtors for each quarter (including any fraction of a quarter) until the Chapter 11Cases are converted, dismissed, or closed, whichever occurs first. Accordingly, the Plan satisfiesthe requirements of section 1129(a)(12) of the Bankruptcy Code.o. Section 1129(a)(13)—Retiree Benefits.56. Pursuant to section 1129(a)(13) of the Bankruptcy Code, and as provided inArticle IV.K of the Plan, the Reorganized Debtors will continue to pay all obligations on accountof retiree benefits (as such term is used in section 1114 of the Bankruptcy Code) on and after theEffective Date in accordance with applicable law. As a result, the requirements of section1129(a)(13) of the Bankruptcy Code are satisfied.p. Sections 1129(a)(14), (15), and (16)—Domestic Support Obligations, Individuals,and Nonprofit Corporations.57. The Debtors do not owe any domestic support obligations, are notindividuals, and are not nonprofit corporations. Therefore, sections 1129(a)(14), 1129(a)(15), and1129(a)(16) of the Bankruptcy Code do not apply to the Chapter 11 Cases.CCaassee 2 244-9-900557755 D Dooccuummeennt t2 29663-2 F Fileiledd i nin T TXXSSBB o onn 1 021/3/113/2/245 P Paaggee 2 267 o of f1 1334527q. Section 1129(b)—Confirmation of the Plan Over Nonacceptance of VotingClasses.58. No Classes rejected the Plan, and section 1129(b) is not applicable here,but even if it were, the Plan may be confirmed pursuant to section 1129(b)(1) of the BankruptcyCode because the Plan is fair and equitable with respect to the Deemed Rejecting Classes. ThePlan has been proposed in good faith, is reasonable, and meets the requirements and all VotingClasses have voted to accept the Plan. The treatment of Intercompany Claims and IntercompanyInterests under the Plan provides for administrative convenience does not constitute a distributionunder the Plan on account of suc

Send us a textFeasibility and safety of autologous cord blood derived cell administration in extremely preterm infants: a single-centre, open-label, single-arm, phase I trial (CORD-SaFe study).Zhou L, McDonald CA, Yawno T, Razak A, Connelly K, Novak I, Miller SL, Jenkin G, Malhotra A.EBioMedicine. 2024 Dec 13;111:105492. doi: 10.1016/j.ebiom.2024.105492. Online ahead of print.PMID: 39674685 Free article.As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

Effective clinical research is a true partnership with individuals, their families, and communities. Guest Jo-Ann Eastwood, PhD, RN , CNS, ACNP-BC, FAHA, FPCNA, FAAN, describes her research in reducing heart disease in premenopausal women in vulnerable populations. Learn how to apply strategies such as relationship-building and utilization of technology, as well as the importance of preceptorship in nursing education.Research Study: Kathuria-Prakash N, Moser DK, Alshurafa N. Watson K, Eastwood JA. Young African American women's participation in an m-Health study in cardiovascular risk reduction: Feasibility , benefits, and barriers. Eur J Cadiovasc Nurs. 2019 Oct;18(7):569-576. doi: 10.1177/1474515119850009. Epub 2019 May 15.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Take a sneak peek at this month's Fertility and Sterility! Articles discussed this month are:   04:20 LGBTQ+ family building: progress but lots more to do/Therapeutic donor insemination for LGBTQ+ families: a systematic review 09:52 Confirmation and pathogenicity of small copy number variations incidentally detected via a targeted next-generation sequencing-based preimplantation genetic testing for aneuploidy platform 23:40 Trends and outcomes of fresh and frozen donor oocyte cycles in the United States 34:11 A survey study evaluating donor gamete utilization rates, patient satisfaction, and fertility treatment outcomes according to desired race and ethnicity 39:29 Racial and ethnic disparities in wait times for donor oocytes 41:16 Return rates and pregnancy outcomes after oocyte preservation for planned fertility delay: a systematic review and meta-analysis 49:23 Longer duration to optimal endometrial thickness in women with premature ovarian insufficiency is associated with clinical pregnancy rate in donor egg cycles 56:30 Feasibility and efficacy of a subcutaneous catheter for controlled ovarian stimulation 01:00:23 International Committee for Monitoring Assisted Reproductive Technology world report: assisted reproductive technology, 2015 and 2016 View Fertility and Sterility October 2024, Volume 122, Issue 5:  https://www.fertstert.org/issue/S0015-0282(24)X0012-6 View Fertility and Sterility at https://www.fertstert.org/

High in fats and low in carbs, ketogenic diets were originally developed in the 1920s to treat children with epilepsy. Now, they've gained popularity for weight loss, and even improved cognitive function. But how much truth is there in the purported brain health benefits we see on social media? In this episode of ‘Your Brain On...', we separate the facts from the fads, and discuss: • What one might eat on a typical ketogenic diet • How ketogenic diets affect brain metabolism • The different ways your brain uses sources of energy — glucose vs. ketones • The latest data on ketogenic diet in Alzheimer's disease patients • What we know about how ketogenic diets and treatment of Alzheimer's • The outcome differences between ketogenic diets and ketone supplements in Alzheimer's • Other evidence-based nutritional approaches for brain health  For this episode, we welcome two world-renowned professionals in the field of nutrition and neuroscience: DR. MATTHEW TAYLOR, PhD, RD, Assistant Professor, Dietetics and Nutrition, Kansas University Medical Center DR. RUSSELL SWERDLOW, MD, Gene and Marge Sweeney Professor of Neurology; Director, Alzheimer's Disease Research Center, Kansas University Medical Center This is... Your Brain On Ketogenic Diets. ‘Your Brain On' is hosted by neurologists, scientists and public health advocates Ayesha and Dean Sherzai. ‘Your Brain On... Ketogenic Diets' • SEASON 4 • EPISODE 4   FOLLOW US Instagram: @thebraindocs Website: TheBrainDocs.com More info and episodes: TheBrainDocs.com/Podcast   REFERENCES 1. Wheless, James W. "History of the ketogenic diet." Epilepsia 49 (2008): 3-5. 2. Krolak-Salmon, Pierre, Russell H. Swerdlow, Thibault Mastain, Catherine Dive-Pouletty, Nick Pooley, and Masoumeh Kisomi. "Efficacy and Safety of Exogenous Ketones in People with Mild Neurocognitive Disorder and Alzheimer's Disease: A Systematic Literature Review." Nutrition Reviews (2024): nuae098. 3. Taylor, Matthew K., Debra K. Sullivan, Jonathan D. Mahnken, Jeffrey M. Burns, and Russell H. Swerdlow. "Feasibility and efficacy data from a ketogenic diet intervention in Alzheimer's disease." Alzheimer's & Dementia: Translational Research & Clinical Interventions 4 (2018): 28-36. 4. Taylor, Matthew K., Russell H. Swerdlow, and Debra K. Sullivan. "Dietary neuroketotherapeutics for Alzheimer's disease: an evidence update and the potential role for diet quality." Nutrients 11, no. 8 (2019): 1910. 5. Koppel, Scott J., and Russell H. Swerdlow. "Neuroketotherapeutics: a modern review of a century-old therapy." Neurochemistry international 117 (2018): 114-125. 6. O'Neill, Blair, and Paolo Raggi. "The ketogenic diet: Pros and cons." Atherosclerosis 292 (2020): 119-126. 7. Crosby, Lee, Brenda Davis, Shivam Joshi, Meghan Jardine, Jennifer Paul, Maggie Neola, and Neal D. Barnard. "Ketogenic diets and chronic disease: weighing the benefits against the risks." Frontiers in nutrition 8 (2021): 702802.

This is a link post. Science just released an article, with an accompanying technical report, about a neglected source of biological risk. From the abstract of the technical report: This report describes the technical feasibility of creating mirror bacteria and the potentially serious and wide-ranging risks that they could pose to humans, other animals, plants, and the environment... In a mirror bacterium, all of the chiral molecules of existing bacteria—proteins, nucleic acids, and metabolites—are replaced by their mirror images. Mirror bacteria could not evolve from existing life, but their creation will become increasingly feasible as science advances. Interactions between organisms often depend on chirality, and so interactions between natural organisms and mirror bacteria would be profoundly different from those between natural organisms. Most importantly, immune defenses and predation typically rely on interactions between chiral molecules that could often fail to detect or kill mirror bacteria due to their reversed [...] --- First published: December 12th, 2024 Source: https://forum.effectivealtruism.org/posts/9pkjXwe2nFun32hR2/technical-report-on-mirror-bacteria-feasibility-and-risks --- Narrated by TYPE III AUDIO.

View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter's Weekly Newsletter Dr. Saum Sutaria is the Chairman and CEO of Tenet Healthcare and a former leader in McKinsey & Company's Healthcare and Private Equity Practices, where he spent almost two decades shaping the field. In this episode, Saum unpacks the complexities of the U.S. healthcare system, providing a detailed overview of its structure, financial flows, and historical evolution. They delve into topics such as private insurance, Medicare, Medicaid, employer-sponsored coverage, drug pricing, PBMs and the administrative burdens impacting the system. Saum's insights help connect healthcare spending to broader economic issues while exploring potential reforms and the role of technology in improving efficiency. Saum highlights how choice and innovation distinguish the U.S. healthcare system, explores the reasons behind exorbitant drug prices, and examines the potential solutions, challenges, and trade-offs involved in lowering costs while striving to improve access, quality, and affordability. The opinions expressed by Saum in this episode are his own and do not represent the views of his employer. We discuss: The US healthcare system: financial scale, integration with economy, and unique challenges [5:00]; Overview of how the US healthcare system currently works and how we got here [9:45]; The huge growth and price impact due to the transition from out-of-pocket payments in the 1950s to the modern, third-party payer model [18:30]; The unique structure and challenges of the US healthcare system compared to other developed nations [22:00]; Overview of Medicare and Medicaid: who they cover, purpose, and impact on healthcare spending [27:45]; Why the US kept a employer-sponsored insurance system rather than pursue universal healthcare [32:00]; The evolution of healthcare insurance: from catastrophic coverage to chronic disease management [36:00]; The challenge of managing healthcare costs while expanding access and meeting increased demand for chronic illness care [44:15]; Balancing cost, choice, and access: how the US healthcare system compares to Canada [48:45]; The role of the US in pharmaceutical innovation, it's impact on drug pricing, and the potential effects of price controls on innovation and healthcare costs [56:15]; How misaligned incentives have driven up drug prices in the US [1:05:00]; The cost of innovation and choice, and the sustainability of the current healthcare cost expenditures in the US in the face of a shrinking workforce and aging population [1:11:30]; Health outcomes: why life expectancy is lower in the US despite excelling at extending lifespan beyond 70 [1:18:45]; Potential solutions and challenges to controlling drugs costs in the US while balancing choice and access and preserving innovation [1:26:15]; Balancing GLP-1 drug innovation with affordability and healthcare spending sustainability [1:40:00]; Reducing healthcare spending: complexities, trade offs, and implications of making needed cuts to healthcare expenditures [1:46:45]; The role of government regulation, opportunities for cost savings, and more [1:56:15]; Hospital billing: costs, charges, complexities, and paths to simplification [2:01:15]; How prioritizing access and choice increased expenditures: reviewing the impact of healthcare exchanges and the Affordable Care Act [2:08:00]; Feasibility of a universal Medicare program, and what a real path to sustainable healthcare looks like [2:15:45]; The challenge of long-term care and the potential of innovation, like device-based therapies and AI, to improve health [2:23:15]; and More. Connect With Peter on Twitter, Instagram, Facebook and YouTube

ethPandaOps publishes research on increasing Ethereum's blob count. Arbitrim introduces Trailblazer AI grants. The EF opens applications for the Next Billion Fellowship. And Starknet v0.13.3 goes live on mainnet. Read more: https://ethdaily.io/599

In this episode, we're joined by Julie Brown, CCM, CPA. We dive in Chapters Two, Three, and Four of the CMAA Capital Improvements Handbook, a comprehensive guide designed to help club decision-makers confidently manage capital improvement projects. This episode is the second in our series of podcasts bringing this content to life, diving into the financing options and feasibility aspects of capital projects. By adopting a strategic and collaborative approach, engaging stakeholders, ensuring robust financial planning, and adhering to regulatory requirements, clubs can successfully navigate the complexities of capital improvements. Access the Capital Improvements Handbook on CMAA Connect

Join Brad Bialy and Steve Gipson on this episode of InSights as they dissect a powerful shift in recruitment and sales strategy: the 25-touchpoint approach. Brad shares insights on why a standard 10-step process no longer cuts it and explains how integrating various marketing channels can significantly enhance a recruiter's reach and engagement. Steve challenges the industry to rethink its relationship with candidates, advocating for transparency and genuine connection to improve trust in recruiting. This episode is essential for anyone in staffing or sales who wants to break through industry limitations and build meaningful connections with clients and candidates alike.   Chapters & Timestamps: [00:00] – Opening Catch-Up: Weather Talk & Marathon Training [04:17] – Introducing the 25-Step Sales Strategy [06:43] – Why Traditional Sales Systems Fall Short [08:43] – Layers of Outreach: PPC, Email, Social Media & Direct Mail [12:08] – Feasibility of Multi-Touchpoint Strategies for Recruiters [17:12] – Building Trust: Combining Sales & Marketing for Greater Reach [20:24] – Viral LinkedIn Post: Candidates, Transparency & Burned Bridges [26:11] – The Industry's Loyalty Problem with Candidates [32:17] – Why Trust Is Essential in Recruitment Relationships [34:32] – Reputation Management: Navigating Negative Stereotypes   InSights is Hosted by Brad Bialy and Steve Gipson Brad Bialy is the host of Take the Stage and InSights, the staffing industry's leading podcasts with close to 175,000 downloads. He has a deep passion for helping staffing and recruiting firms achieve their business objectives through strategic marketing concepts. For over a decade, Brad has developed a proven track record of motivating and educating staffing industry professionals at over 150 industry-specific conferences and webinars. His keen eye for strategy and delivery has resulted in multiple industry award-winning social media campaigns, making him a sought-after speaker and expert. A recruiting industry veteran with over 15 years of experience, Steve Gipson is the Director of Sales and Operations at Recruiters Websites. After spending seven years as a recruiter with a boutique search firm, he joined Recruiters Websites, a digital marketing agency specializing in the recruitment industry. For the past decade, Recruiters Websites has helped over 800 firms of all sizes and specialties enhance their digital presence and make more placements through their expertise in digital marketing, website development, and SEO services.

Top experts debate the potential for open-source, community-driven AI to challenge tech giants and explore the unique advantages of decentralized approaches. Key topics include: ►Feasibility of competitive open-source AI models ►Advantages of decentralized training approaches ►Challenges in compute resources and talent acquisition ►The role of crypto incentives in AI development ►Balancing open-source principles with value capture ►Governance challenges for decentralized AI projects ►Potential risks and obstacles for decentralized AI This engaging debate bridges the gap between decentralized infrastructure, AI development, and crypto economic models. Gain insights from industry leaders on how projects like Nous, Gensyn, Ambient, and Prime Intellect are working to democratize AI and create more efficient, trustless systems. Watch more sessions from Crypto x AI Month here: https://delphidigital.io/crypto-ai --- Crypto x AI Month is the largest virtual event dedicated to the intersection of crypto and AI, featuring 40+ top builders, investors, and practitioners. Over the course of three weeks, this event brings together panels, debates, and discussions with the brightest minds in the space, presented by Delphi Digital. Crypto x AI Month is free and open to everyone thanks to the support from our sponsors: https://olas.network/ https://venice.ai/ https://near.org/ https://mira.foundation/ https://www.theoriq.ai/ --- Follow the Speakers: - Tommy Shaughnessy on Twitter/X ► https://x.com/shaughnessy119 - Travis Good on Twitter/X ► https://x.com/IridiumEagle - Dillon Rolnick on Twitter/X ► https://x.com/DillonRolnick - Johannes Hagemann on Twitter/X ► https://x.com/johannes_hage - Ben Fielding on Twitter/X ► https://x.com/fenbielding --- Chapters 00:00 Introduction to Decentralized vs Centralized AI Training 02:46 The Viability of Decentralized AI Models 05:57 Technical and Economic Challenges in AI Training 09:09 The Future of Specialized vs Generalist AI Models 12:01 The Role of Regulatory Environment in AI Development 14:56 The Importance of Model Maintenance and Updates 18:06 The Economics of Decentralized AI 20:56 Talent and Collaboration in Open Source AI 23:58 The Efficiency of Decentralized Systems 27:04 The Political Implications of AI Control 30:12 Recent Breakthroughs in Decentralized Training 33:04 The North Star of Open Source AI 35:53 The Intersection of Open Source AI and Crypto 38:59 The Future of Competition in AI Markets 46:22 Decentralization and Competition in the Market 49:34 The Evolution of User Interfaces and Trustlessness 52:31 The Convergence of AI and Crypto 56:30 The Role of Agents in the Economy 01:01:27 Open Source AI and Value Capture 01:06:23 Governance Challenges in Decentralized Systems 01:23:24 Skepticism and Future Risks in AI and Crypto Disclaimer All statements and/or opinions expressed in this interview are the personal opinions and responsibility of the respective guests, who may personally hold material positions in companies or assets mentioned or discussed. The content does not necessarily reflect the opinion of Delphi Citadel Partners, LLC or its affiliates (collectively, “Delphi Ventures”), which makes no representations or warranties of any kind in connection with the contained subject matter. Delphi Ventures may hold investments in assets or protocols mentioned or discussed in this interview. This content is provided for informational purposes only and should not be misconstrued for investment advice or as a recommendation to purchase or sell any token or to use any protocol.

This September, we're doing something a bit different. We're revisiting the basics with a refresher on the eight pillars of rocking retirement—four financial and four non-financial pillars that form the foundation for a great life. Too often, retirement planning gets bogged down with too many details and the pressure to get everything right. But in my experience, focusing on the most important things gets you 90% of the way there. This month, we'll air classic episodes to revisit these pillars, starting today with the first two financial pillars: Vision and Feasibility.The first financial pillar we are going to discuss is VISION. How do you start to figure out your vision in retirement? We would suggest reconnecting with who you actually are outside of your identity as an employee and identifying your core values. The second pillar in the financial realm is having a FEASIBLE plan. The objective is to establish a foundation of a safe path that is feasible given the resources and the choices that you are willing to make. OUTLINE OF THIS EPISODE OF THE RETIREMENT ANSWER MANPRACTICAL PLANNING SEGMENT- 00:28 September will focus on the eight pillars of rocking retirement- 08:00 First two pillars of rock retirement are vision and feasibility- 08:14 Vision: What do you want when you retire? - 13:28 What are some of the obstacles to creating a vision in retirement?- 17:44 The next pillar in the financial realm is having a feasible planLISTENER QUESTIONS- 24:10 Listener Scott has a tip about going from two to one- 26:13 Bill discusses piecake - 27:44 Our next question is from Steve related to asset allocation in retirement- 33:53 Another listener, Steve, wants to know if a stable value fund is a good investmentBRING IT ON - 38:33 Kevin Lyles talks passion in work and volunteering in retirement SMART SPRINT- 45:55 Think about your life as a clean slate✍️ Episode ReferencesSix Shot Saturdayhttps://sixshotsaturday.comThe Top Five Regrets of the Dying- Bronnie Ware https://bronnieware.com/regrets-of-the-dying/The Retirement Manifesto- Fritz Gilberthttps://www.theretirementmanifesto.com/Stocks for the Long Run- Jeremy Siegelhttps://www.amazon.com/Stocks-Long-Run-Definitive-Investment/dp/0071800514