Podcasts about Feasibility

Dr. Linda Chu reviews recent articles in the Generative AI Collection, covering clinical history extraction, case interpretation with vision language models, and report proofreading.   The articles covered in the podcast are: Leveraging Large Language Models to Generate Clinical Histories for Oncologic Imaging Requisitions | Radiology   Assessing Completeness of Clinical Histories Accompanying Imaging Orders Using Adapted Open-Source and Closed-Source Large Language Models | Radiology   Impact of Multimodal Prompt Elements on Diagnostic Performance of GPT-4V in Challenging Brain MRI Cases | Radiology   Generative Large Language Models Trained for Detecting Errors in Radiology Reports | Radiology   Large-Scale Validation of the Feasibility of GPT-4 as a Proofreading Tool for Head CT Reports | Radiology

AI for Site Feasibility: Streamlining Zoning, Codes, and Permits for ArchitectsIn this episode of the podcast, Gayathri (G3) Venkataraman, founder and CEO of Dota.ai, shares her inspiring journey from leading product teams at Microsoft and DocuSign to launching her own startup focused on transforming site feasibility and permitting in the construction industry. Frustrated by outdated, fragmented data systems, G3 created Dota.ai to consolidate information on land use, zoning, and building codes into one streamlined, accessible platform. She explains how AI can dramatically speed up the pre-development process, allowing architects and developers to make smarter, faster decisions.G3 dives into the unique challenges of integrating advanced technology into the traditionally conservative construction sector and discusses the future potential of AI to reshape urban planning and civic tech. She also reflects on her mission to empower real estate and design professionals, ultimately driving both operational efficiency and community impact. As a nonprofit board chair, G3 believes deeply in using technology for the greater good and shares insights on balancing innovation with societal responsibility.Throughout the conversation, she offers practical advice to small firm architects on embracing change and cultivating a mindset of continuous improvement in their practices.This week at EntreArchitect Podcast, AI for Site Feasibility: Streamlining Zoning, Codes, and Permits for Architects with Gayathri (G3) Venkataraman.Connect with G3 online at Dota.ai or find her on LinkedIn and Instagram.Please Visit Our Platform SponsorsArcatemy is Arcat's Continuing Education Program. Listen to Arcat's Detailed podcast and earn HSW credits. As a trusted provider, Arcat ensures you earn AIA CE credits while advancing your expertise and career in architecture. Learn more at Arcat.com/continuing-education.Visit our Platform Sponsors today and thank them for supporting YOU... The EntreArchitect Community of small firm architects.

Have you ever wondered what makes the difference between a successful property development and a cash-draining development nightmare? Welcome back for part 2 of our discussion with Adam Barry from Develop Capital. Today, Adam dives deeper into property development strategies, focusing on risk mitigation and the critical factors he considers when selecting development sites, such as market demand and location. Adam also shares his approach to balancing development and holding properties, highlighting how he ensures profitability through careful planning and risk management. Whether you’re renovating or building from the ground up, Adam’s insights will guide you in navigating market shifts and maximising returns. This episode is packed with valuable tips for anyone looking to level up their property development strategy. Tune in now—let’s go inside! Resource Links: Get your Strategic Portfolio Plan and our help with Buying Your Next Perth Property (https://www.investorsedge.com.au/invest-in-perth-property/) Get email updates about suburb intelligence reports and exclusive invites to our webinars, events, and workshops. Join (investorsedge.com.au/join) Join the Perth Property Investment Facebook Group (https://www.facebook.com/groups/perthpropertyinvestors) Join Jarrad Mahon’s Property Investor Update (https://www.investorsedge.com.au/join) For more info on our award-winning and highly rated Property Management services that give you guaranteed peace of mind (https://www.investorsedge.com.au/perth-property-management-specialists/) For more info on how our Property Sales services can ensure you get the best selling price while handling all the stress for you (https://www.investorsedge.com.au/selling-your-perth-property/) Episode Highlights: Intro [00:00] Feasibility and Non-Negotiables in Property Development [04:29] Non-Negotiables in Site Selection [06:25] Market Analysis and Risk Mitigation [18:54] Negotiation Strategies and Market Conditions [31:48] Mindset and Decision-Making in Development [32:54] Thank you for tuning in! If you liked this episode, please don’t forget to subscribe, tune in, and share this podcast. About the Guest: Adam Barry is a seasoned property developer and investor based in Perth, Australia, who began his career in 2008 by renovating and selling his first home for a solid profit. He specializes in value-adding projects such as renovations, subdivisions, and medium-scale developments, focusing on efficient upgrades that boost property value without major structural changes. Barry manages multiple projects simultaneously and emphasises education, market research, and networking to minimize risks and maximize returns. His approach targets properties with strong potential for cosmetic improvement, aiming for a 15% to 20% profit margin after costs. Connect with Adam: LinkedIn: https://www.linkedin.com/in/adam-barry-33aa74181/ Develop Capital https://www.developcapital.com.au/ Connect with Perth Property Insider: Subscribe on YouTube: https://www.youtube.com/@InvestorsedgeAu Like us on Facebook: https://www.facebook.com/investorsedge See omnystudio.com/listener for privacy information.

U.S. Gold Corp CEO George Bee joined Steve Darling from Proactive to announce a key advancement in the company's development strategy for its flagship CK Gold Project in southeast Wyoming. The company has contracted two industry leaders—Micon International and Halyard—to lead the next phase of engineering and feasibility work, with the goal of delivering a robust and executable development plan that brings the project into production on time and on budget. Following a competitive evaluation process, U.S. Gold selected Micon and Halyard for their deep expertise in concentrator design and process engineering, and their reputation for “right-sizing” projects to meet operational and economic goals. The firms have a combined track record of over 762 completed projects and more than 1,260 technical reports, making them trusted global authorities in mineral project development. The primary objective of this next phase is to develop a site-specific AACE Class 3 cost estimate—a highly detailed engineering and cost forecast level required for capital funding decisions—and a comprehensive project execution plan. These deliverables will form the backbone of the company's Definitive Feasibility Study (DFS), which is expected to be completed by late 2025. In addition to the Micon-Halyard partnership, U.S. Gold has also retained Ken Murray of Captrics Consulting to oversee the finalization of engineering studies and lead the development of the Project Execution Plan. Murray brings more than 25 years of capital project and innovation experience across a wide range of commodities, industries, and geographies. Renowned for his strategic insight and innovative thinking, Murray has held senior roles with Kemix, DRA Global, Accenture, Ausenco, SNC-Lavalin, and Inspire Resources, supporting projects for major mining companies such as BHP, AngloPlatinum, Assmang, Alamos, New Gold, and Goldcorp. The CK Gold Project is a cornerstone asset for U.S. Gold Corp, offering a compelling combination of scale, grade, and jurisdictional stability. As development accelerates with trusted technical partners and experienced leadership in place, the company is well-positioned to transform CK Gold into a strategic, U.S.-based source of gold and copper in a market increasingly focused on domestic resource security. #proactiveinvestors #usgoldcorp #nasdaq #usau #mining #USGoldCorp #CKGoldProject #GoldMining #CopperMining #WyomingMining #MiningStocks #GeorgeBee #GoldPrice #FeasibilityStudy #JuniorMining #ProactiveInvestors

Portable Device Feasibility Abstract Chris and Fred discuss how we assess product feasibility … at the concept stage! Great topic. Key Points Join Chris and Fred as they discuss product feasibility when it is nothing more than a concept. There is a lot to unpack here! This comes from a question raised by a Singaporean […] The post SOR 1083 Portable Device Feasibility appeared first on Accendo Reliability.

The NACE Journal Club with Dr. Neil Skolnik, provides review and analysis of recently published journal articles important to the practice of primary care medicine. In this episode Dr. Skolnik and guests review the following publications:1. Effects of Combining Coronary Calcium Score With Treatment on PlaqueProgression in Familial Coronary Artery Disease A Randomized Clinical Trial JAMA 2025. Discussion by:Guest: Michael J. Blaha, MD, MPHProfessor of Cardiology and Epidemiology and presently serves as theDirector of Clinical Research for the Johns Hopkins Ciccarone Center for thePrevention of Cardiovascular DiseaseDirector of the Cardiometabolic ClinicProgram Director for the Preventive Cardiology Fellowship.2. Creatine monohydrate pilot in Alzheimer's: Feasibility, brain creatine, and cognition. Alzheimer's Dement. 2025. Discussion by:Guest:Michael Devano, DO Attending Family Physician Christiana Care Health System3. Structured Exercise after Adjuvant Chemotherapy for Colon Cancer. The New England Journal of Medicine. Discussion by:Guest:Joseph Gonnella, MD Resident– Family MedicineResidency Program, Jefferson Health – AbingtonMedical Director and Host, Neil Skolnik, MD, is an academic family physician who sees patients and teaches residents and medical students as professor of Family and Community Medicine at the Sidney Kimmel Medical College, Thomas Jefferson University and Associate Director, Family Medicine Residency Program at Abington Jefferson Health in Pennsylvania. Dr. Skolnik graduated from Emory University School of Medicine in Atlanta, Georgia, and did his residency training at Thomas Jefferson University Hospital in Philadelphia, PA. This Podcast Episode does not offer CME/CE Credit. Please visit http://naceonline.com to engage in more live and on demand CME/CE content.

Canagold Resources CEO Catalin Kilofliski joined Steve Darling from Proactive to provide an update on the company's flagship New Polaris gold project, which is steadily advancing toward a feasibility study and production decision. Located in British Columbia, the project is drawing increasing attention for its exceptionally high-grade gold resource and new upside from a critical mineral byproduct—antimony. Kilofliski emphasized that New Polaris may host the highest-grade undeveloped gold deposit in the world, with an average grade of 13 grams per tonne (g/t) of gold. The current resource includes over one million ounces of gold, which is now being evaluated as part of ongoing feasibility-level work to define the project's development path. A major update in the project's evolution is the recent recognition of antimony as an economic byproduct. Kilofliski shared that Canagold has published a NI 43-101 compliant antimony resource of approximately 7,000 tons, which is now being incorporated into future mine planning. “Anything we would get paid eventually for antimony, it's on top, which is great,” he said, noting that the costs associated with mining the antimony are already absorbed by the gold production, making it a pure bonus in terms of economics. This development is particularly timely, as antimony has been designated a critical mineral by both Canada and the United States, due to its strategic importance in defense, energy storage, and semiconductors, and growing concerns over global supply chain vulnerabilities. As demand for antimony rises, Canagold is well-positioned to benefit from both rising prices and increasing geopolitical interest in secure domestic sources. The company continues to advance permitting efforts in British Columbia, with both regulatory work and technical feasibility studies actively underway. These efforts are laying the groundwork for a future construction decision while engaging with stakeholders and regulatory bodies to ensure a clear path to development. Kilofliski also highlighted Canagold's strong financial position, supported by its major shareholder, Sun Valley Investments, which owns approximately 50% of the company's outstanding shares. Sun Valley's involvement provides Canagold with stable, long-term financial backing, enabling the company to maintain momentum without reliance on near-term dilutive financing. With high-grade gold, newly defined critical minerals, supportive capital partners, and ongoing regulatory progress, Canagold Resources is shaping New Polaris into a uniquely attractive development-stage asset, offering both near-term advancement and long-term strategic value in a resource-constrained world. #proactiveinvestors #canagoldresources #tsx #ccm #otcqb #crcuf #mining #Antimony #CriticalMinerals #NewPolaris #MiningStocks #FeasibilityStudy #TSX

Any donation is greatly appreciated! 47e6GvjL4in5Zy5vVHMb9PQtGXQAcFvWSCQn2fuwDYZoZRk3oFjefr51WBNDGG9EjF1YDavg7pwGDFSAVWC5K42CBcLLv5U OR DONATE HERE: https://www.monerotalk.live/donate TODAY'S SHOW: In this episode of Monero Talk, Douglas Tuman speaks with cryptographic engineer Sean Coughlin about "Grease," his proposed layer 2 payment channel protocol for Monero. They delve into its technical design, how it compares to Bitcoin's Lightning Network, and its potential to streamline Monero transactions by enabling off-chain payments without routing complexities. Sean shares insights from MoneroKon, discusses Monero's resilience despite theoretical attack vectors, and explains how Grease aligns with upcoming upgrades like Full Chain Membership Proofs (FCMP++). He also touches on real-world use cases, wallet integration, and Grease's flexible, decentralized approach aimed at boosting Monero's usability and innovation. TIMESTAMPS: (00:03:40) Sean's background and involvement in Monero development (00:06:29) Privacy strength of Monero and resistance to chain analysis (00:10:21) Comparisons to other privacy coins (e.g., Zcash) (00:12:26) MoneroKon research papers and Eclipse attacks on nodes. (00:14:35) Discussion on Full Chain Membership Proofs (FCMP++) and its progress. (00:18:37) Clarifying Zero-Knowledge Proofs and Monero's cryptographic foundation. (00:22:11) History and capabilities of Turing-complete ZKPs in other projects. (00:26:16) Philosophy of "minimaxing" – Monero focuses only on privacy. (00:27:19) Debating if Monero needs to become Turing complete. (00:31:05) Introduction to "Grease" – Monero-compatible payment channel proposal. (00:31:42) Technical hurdles for payment channels in Monero (e.g., no transaction chaining). (00:35:01) Feasibility of Grease today vs. post-FCMP++. (00:36:38) Clarifying the benefits and use cases of Grease (instant payments, off-chain privacy). (00:39:39) Why Layer 2 doesn't conflict with Monero's scaling philosophy. (00:46:41) Grease vs. Bitcoin Lightning Network (00:56:05) Feedback from MoneroKon and Reddit – cautious optimism from developers. (01:05:39) Trade-offs: centralization vs. security in protocol design GUEST LINKS: https://x.com/seanrcoughlin Purchase Cafe & tip the farmers w/ XMR! https://gratuitas.org/ Purchase a plug & play Monero node at https://moneronodo.com SPONSORS: Cakewallet.com, the first open-source Monero wallet for iOS. You can even exchange between XMR, BTC, LTC & more in the app! Monero.com by Cake Wallet - ONLY Monero wallet (https://monero.com/) StealthEX, an instant exchange. Go to (https://stealthex.io) to instantly exchange between Monero and 450 plus assets, w/o having to create an account or register & with no limits. WEBSITE: https://www.monerotopia.com CONTACT: monerotalk@protonmail.com ODYSEE: https://odysee.com/@MoneroTalk:8 TWITTER: https://twitter.com/monerotalk FACEBOOK: https://www.facebook.com/MoneroTalk HOST: https://twitter.com/douglastuman INSTAGRAM: https://www.instagram.com/monerotalk TELEGRAM: https://t.me/monerotopia MATRIX: https://matrix.to/#/%23monerotopia%3Amonero.social MASTODON: @Monerotalk@mastodon.social MONERO.TOWN: https://monero.town/u/monerotalkAny donation is greatly appreciated!Any donation is greatly appreciated!

Featuring perspectives from Ms Ilene Galinsky, Dr Michael J Mauro, Dr Neil P Shah and Dr Sara M Tinsley-Vance, including the following topics: Introduction: Chronic Myeloid Leukemia (CML) as a Model for Targeted Treatment (0:00) Biology of CML; Role of First- and Second-Generation Tyrosine Kinase Inhibitors (TKIs) as Initial Treatment for Chronic-Phase (CP) CML (12:37) Role of Asciminib for Newly Diagnosed CP-CML (47:46) Feasibility of TKI Discontinuation for Patients with Sustained Response to Treatment (1:14:06) Management of CP-CML After Failure of Initial Therapy (1:23:04) NCPD information and select publications

First Phosphate Corp CEO John Passalacqua talked with Proactive's Stephen Gunnion about the company's recent metallurgical testing progress and next steps toward a feasibility study. The company has collected a 5,000-kilogram bulk sample to refine its phosphate separation process and further validate its earlier pilot results, which had already achieved nearly 90% phosphate recovery. Passalacqua emphasized the significance of this stage, saying, “Now it's a second stage as we advance towards our feasibility study… to get down to what will be our real live scale separation process.” The Northern and Mountain zones remain the focal points for the first decade of production, chosen for their high phosphate concentration and accessible terrain. He also shared findings of up to 45% apatite from surface stripping and noted that the project area spans 2.5km by 0.5km, with confirmed mineralization to depths of 300m and remaining open. The next steps include completing definition drilling and validating resource estimates to transition from inferred to measured classification. Passalacqua also highlighted investor-ready metrics from the PEA, including a C$2.1 billion NPV and a 37% IRR, along with strong logistics and existing offtake agreements. For more updates, visit Proactive's YouTube channel. Don't forget to like the video, subscribe, and turn on notifications. #FirstPhosphate #PhosphateMining #CriticalMinerals #BatteryMetals #MiningInvesting #FeasibilityStudy #ResourceDevelopment #CanadianMining #PhosphoricAcid #MetallurgicalTesting

Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Safety and Feasibility of On-the-Table Pharmacomechanical Lysis for Acute Intermediate-Risk Pulmonary Embolism: The RESCUE-II Study.

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In this episode Adam shares a new development in a prospective project, and introduces the idea of a Pre-Design and Feasibility study. 

Creatine for Alzheimer's — let's separate the hype from the hope. A new study has caused a stir in June 2025, but lead researcher Matthew K. Taylor told us: “ I don't think I can recommend it to a patient that this is going to ultimately have some sort of cognitive influence.” We speak to Dr. Taylor and Dr. Russell Swerdlow in this episode, discussing: • Role of creatine in your brain, and why it matters for energy metabolism • What the 2025 study found (and why it wasn't designed to prove effectiveness) • How scientific nuance gets lost in supplement hype • Why even promising early data must be handled with care • The vital difference between hype and hope Dr. Russell Swerdlow, MD is Director of the University of Kansas Alzheimer's Disease Research Center. Dr. Matthew Taylor, PhD, RD is Associate Professor of Dietetics & Nutrition at the University of Kansas Medical Center. This is... Your Brain On Creatine. SUPPORTED BY: NEURO World. Help your brain thrive, now and into the future: https://neuro.world/  ‘Your Brain On' is hosted by neurologists, scientists, and public health advocates Ayesha and Dean Sherzai.  ‘Your Brain On... Creatine' • SEASON 5 • EPISODE 8 LINKS  Dr. Taylor at the University of Kansas: https://www.kumc.edu/mtaylor3.html Dr. Swerdlow at the University of Kansas: https://www.kumc.edu/rswerdlow.html REFERENCES 1. Smith AN, Choi IY, Lee P, Sullivan DK, Burns JM, Swerdlow RH, Kelly E, Taylor MK. Creatine monohydrate pilot in Alzheimer's: Feasibility, brain creatine, and cognition. Alzheimer's & Dementia: Translational Research & Clinical Interventions. 2025 Apr;11(2):e70101. 2. Taylor MK, Burns JM, Choi IY, et al. Protocol for a single-arm, pilot trial of creatine monohydrate supplementation in patients with Alzheimer's disease. Pilot Feasibility Study. 2024;10(1):42.  3. Habeck C, Risacher S, Lee GJ, et al. Relationship between baseline brain metabolism measured using [18 F]FDG PET and memory and executive function in prodromal and early Alzheimer's disease. Brain Imaging Behav. 2012;6(4):568-83.  4. Kreider RB, Kalman DS, Antonio J, et al. International Society of Sports. Nutrition position stand: safety and efficacy of creatine supplementation in exercise, sport, and medicine. J Int Soc Sports Nutr. 2017;14:18.

Everyone has goals — some are monumental, others modest — but every goal matters. Join guest Szu-chi Huang, an expert in sustaining enthusiasm for individuals, customers, and employees across global corporations and organizations, as she delves into the science of motivation. Discover how the gap between where you are and where you want to be is bridged by a dynamic blend of psychology, sociology, behavioral economics, neuroscience, and the latest in AI. The secret to achieving your goals? Stay adaptable. If one approach falters, switch gears to keep your drive alive, Huang tells host Russ Altman on this episode of Stanford Engineering's The Future of Everything podcast.Have a question for Russ? Send it our way in writing or via voice memo, and it might be featured on an upcoming episode. Please introduce yourself, let us know where you're listening from, and share your question. You can send questions to thefutureofeverything@stanford.edu.Episode Reference Links:Stanford Profile: Szu-chi HuangConnect With Us:Episode Transcripts >>> The Future of Everything WebsiteConnect with Russ >>> Threads / Bluesky / MastodonConnect with School of Engineering >>> Twitter/X / Instagram / LinkedIn / FacebookChapters:(00:00:00) IntroductionRuss Altman introduces Szu-Chi Huang, professor of marketing at Stanford GSB.(00:03:31) Studying MotivationSzu-chi shares what led her to study motivational science(00:04:03) Defining MotivationMotivation as the drive to close the gap between current and ideal self.(00:04:57) The Science of MotivationStudying motivation through behavioral and neurological data.(00:05:48) Why It Matters in BusinessHow motivation science applies to leaders, teams, and customers.(00:06:39) Motivation FrameworkThe strategies needed in order to stay motivated over time.(00:07:42) The Mindset of MotivationThe different mindsets needed throughout the stages of motivation.(00:09:21) Motivating Kids to Choose HealthyA Collaboration with UNICEF to study what motivates children.(00:10:55) Gamified Coupons in PanamaA study using gamified coupons to influence children's food choices.(00:14:26) Loyalty Programs as MotivationHow customer reward programs act as structured goal journeys.(00:16:47) Progress Versus PurposeThe different incentives needed in each stage of loyalty programs.(00:18:29) Retirement Saving LessonsHow financial institutions apply motivational science to long-term goals.(00:21:12) Motivation in Social ContextThe role of social connections in goal pursuit and sustaining motivation.(00:26:10) Designing Apps for MotivationHow redesigning user interfaces can help users stay motivated.(00:27:20) AI as a Motivation CoachUsing AI to personalize feedback across all stages of goal pursuit.(00:30:09) Starting and Sustaining a GoalPractical strategies for launching and sustaining a goal.(00:31:57) Conclusion Connect With Us:Episode Transcripts >>> The Future of Everything WebsiteConnect with Russ >>> Threads / Bluesky / MastodonConnect with School of Engineering >>>Twitter/X / Instagram / LinkedIn / Facebook

This week on The Beat, CTSNet Editor-in-Chief Joel Dunning speaks with CTSNet JANS Editor Dr. Mateo Marin-Cuartas, a cardiac surgeon in the University Department of Cardiac Surgery at the Leipzig Heart Center, Germany, about surgical aortic valve replacement (SAVR) vs transcatheter aortic valve replacement (TAVR). Chapters 00:00 Intro 00:57 Dr. Marin-Cuartas Feature 02:28 SHURUI Robot Feasability 05:09 Touching as Diagnostic Test 09:06 Removal of Rib Stab Hardware 13:00 Resectable EGFR-Positive NSCLC 16:12 On-Pump Beating Heart MVR 17:56 Post-Infarction Myocardial Rupture 19:52 Head-First Graft Technique 22:18 SAVR vs TAVR, Dr. Marin-Cuartas 46:44 Upcoming Events 47:52 Closing They discuss SAVR and TAVR guidelines, the suitability of SAVR vs TAVR for patients aged 65-75, and mechanical heart valves. They also explore surgery after TAVR, TAVR after TAVR, and the future of addressing aortic valve stenosis.   Joel also highlights recent JANS articles on the safety and feasibility of novel single-port robotic-assisted lobectomy/segmentectomy for lung cancer, touching (proximity) as a companion diagnostic test, long-term outcomes after removal of rib stabilization hardware in patients with blunt chest trauma, and advancing the needle on the management of resectable EGFR-positive NSCLC.    In addition, Joel explores an on-pump beating heart mitral valve repair through right anterior minithoracotomy, post-infarction myocardial rupture treated with surgical repair and graded mechanical support, and a head-first graft technique in aortic arch replacement. Before closing, Joel highlights upcoming events in CT surgery.    JANS Items Mentioned  1.) Safety and Feasibility of Novel Single-Port Robotic-Assisted Lobectomy/Segmentectomy for Lung Cancer  2.) Touching (Proximity) as a Companion Diagnostic Test   3.)  Long-Term Outcomes After Removal of Rib Stabilization Hardware in Patients With Blunt Chest Trauma  4.) Advancing the Needle on the Management of Resectable EGFR-Positive NSCLC: Is Neoadjuvant Osimertinib the Answer?  CTSNET Content Mentioned  1.) On-Pump Beating Heart Mitral Valve Repair Through Right Anterior Mini Thoracotomy  2.) Drain, Patch, Unload: Post-Infarction Myocardial Rupture Treated With Surgical Repair and Graded Mechanical Support  3.) Head-First Graft Technique in Aortic Arch Replacement  Other Items Mentioned  1.) Career Center   2.) CTSNet Events Calendar  Disclaimer The information and views presented on CTSNet.org represent the views of the authors and contributors of the material and not of CTSNet. Please review our full disclaimer page here.

Dr. Robert Quartermain, Co-Chairman, Director and CEO of Dakota Gold (NYSE American: DC), joined me for an update on their Richmond Hill Project and Maitland Gold Project, both located in the historic Homestake District of South Dakota, near existing mining infrastructure.   The company is advancing its Richmond Hill project toward eventual surface heap leach gold operation as soon as 2029, and expanding the high-grade gold mineralization discovered at the Maitland Gold Project toward an initial resource estimate.   We start having Robert share his background in the industry, as he was previously the Executive Chairman of Pretium Resources Inc., which he founded in October 2010. Prior to Pretium, he was President and Chief Executive Officer of Silver Standard Resources Inc. (now SSR Mining Inc.) for 25 years from 1985-2010. Not only does he have a wealth of experience in developing and constructing producing mines, but he has assembled a solid management team and board filled with industry veterans that have worked in either the Homestake Mine, before it closed down, or the currently producing nearby Wharf Mine, operated by Coeur Mining.   Richmond Hill is one of the largest undeveloped oxide gold resources in the United States being advanced by a junior mining company, with over 6 million ounces of gold and over 60 million ounces of silver moving along the pathway of development into heap leach production as soon as 2029. Principle Projects on Private Land which equates to a positive attribute for efficient permitting with State and County organizations.   S-K 1300 Mineral Resource (Heap Leachable): 65 M oz M&I Gold, 2.61 M oz Inferred Gold 1 M oz M&I Silver, 22.8 M oz Inferred Silver   Dakota Gold has engaged the current consulting groups based on their capabilities to deliver an Initial Assessment with Cash Flow (IACF) in mid-2025 (similar to a PEA).  This economic study will be based on a 30,000 ton per day crushing circuit, and further the project towards ultimate production. The Company continues Feasibility planning with M3 as the overall Study Manager as well as the lead for processing, while RESPEC will manage the mining and environmental aspects   There are currently two drill rigs turning at Richmond Hill. In 2025, the Company expects to drill ~80,000 feet (24,384 meters) using a combination of Reverse Circulation and Core drilling. The primary focus of the program is to collect metallurgical samples for the Feasibility Study, infill, and expansion resource drilling in the northeast corner of the Project area. This area is expected to be mined at the beginning of the mine plan and is higher-grade than the overall deposit.   At the Maitland Gold Project the Company is currently assessing the exploration data collected to date from the JB Gold Zone and the Unionville Zone with the intent of outlining an initial inferred gold resource. The work is expected to be completed in the fall of 2025. To date the JB Gold Zone has encountered a number of high-grade intersections which average 10.76 g/t Au over 4.0 meters.   With the recent financing announced March 20, 2025, the Company currently has a cash balance of $47 million as noted in the filed 10Q as at March 31, 2025, and is fully financed through the IACF and the subsequent completion of its Feasibility Study on the Project.   If you have any questions for Bob Quartermain regarding Dakota Gold, then please email those in to me at Shad@kereport.com.   In full disclosure, Shad is a shareholder of Dakota Gold at the time of this recording, and may choose to buy or sell shares at any time.   Click here to follow the latest news from Dakota Gold

Surge Battery Metals CEO Greg Reimer joined Steve Darling from Proactive to announce the release of the 2025 Preliminary Economic Assessment for the company's flagship Nevada North Lithium Project —a major milestone that confirms the project's strong economic potential as a scalable, long-life, and low-cost lithium operation. The PEA outlines a compelling development scenario for a conventional open-pit mine paired with dry-stack tailings and on-site sulfuric acid leach processing to produce battery-grade lithium carbonate equivalent. The proposed operation leverages Nevada's mining-friendly jurisdiction and infrastructure, setting the stage for North American-based supply of critical battery materials. Reimer detailed that the project is structured around a 42-year mine life, with production split into two major phases. In Phase 1, the mine will process 2.58 million tonnes per annum (Mtpa) of ore. Phase 2, which kicks off in Year 4, will double processing throughput to 5.15 Mtpa, supporting significant increases in production volumes. The operational strategy prioritizes the shallowest and highest-grade lithium zones, ensuring early cash flow and optimal economics. As a result, production of battery-grade LCE peaks at 109,100 tonnes in Year 6, with an average of 86,300 tonnes/year over the life of mine. In total, the project is projected to deliver 3.63 million tonnes of LCE at a recovery rate of 82.8%. One of the most notable figures in the report is the net present value (NPV) of the project: US$9.21 billion, based on the latest assay results received in January. The project's internal rate of return (IRR) and capital efficiency metrics are expected to be detailed in subsequent reports, but the current valuation already positions NNLP among the most promising lithium development assets in North America. Looking ahead, Reimer emphasized that Surge Battery Metals is committed to rapidly advancing and de-risking the NNLP through upcoming Pre-Feasibility and Feasibility studies. The company will focus on refining process efficiencies, optimizing mine design, and engaging with potential strategic partners to support future development and financing. #proactiveinvestors #surgebatterymetals #tsxv #nili #otcqb #otcqx #nilif #Lithium #NevadaNorth #Mining #CriticalMinerals #BatteryMetals #LithiumInvesting #MiningNews #ProactiveInvestors #ResourceEstimates #MiningPEA #GregReimer #EVMetals #CleanEnergy

Dans cet épisode, Simon explique les bienfaits de la créatine et démystifie les méconceptions par rapport à ses effets et son utilisation. Références : Kreider, R. B., Kalman, D. S., Antonio, J., Ziegenfuss, T. N., Wildman, R., Collins, R., Candow, D. G., Kleiner, S. M., Almada, A. L., & Lopez, H. L. (2017). International Society of Sports Nutrition position stand: safety and efficacy of creatine supplementation in exercise, sport, and medicine. Journal of the International Society of Sports Nutrition, 14, 18. https://doi.org/10.1186/s12970-017-0173-zLanhers, C., Pereira, B., Naughton, G., Trousselard, M., Lesage, F. X., & Dutheil, F. (2015). Creatine Supplementation and Lower Limb Strength Performance: A Systematic Review and Meta-Analyses. Sports medicine (Auckland, N.Z.), 45(9), 1285–1294. https://doi.org/10.1007/s40279-015-0337-4Lanhers, C., Pereira, B., Naughton, G., Trousselard, M., Lesage, F. X., & Dutheil, F. (2017). Creatine Supplementation and Upper Limb Strength Performance: A Systematic Review and Meta-Analysis. Sports medicine (Auckland, N.Z.), 47(1), 163–173. https://doi.org/10.1007/s40279-016-0571-4Prokopidis, K., Giannos, P., Triantafyllidis, K. K., Kechagias, K. S., Forbes, S. C., & Candow, D. G. (2023). Effects of creatine supplementation on memory in healthy individuals: a systematic review and meta-analysis of randomized controlled trials. Nutrition reviews, 81(4), 416–427. https://doi.org/10.1093/nutrit/nuac064Smith, A. N., Choi, I. Y., Lee, P., Sullivan, D. K., Burns, J. M., Swerdlow, R. H., Kelly, E., & Taylor, M. K. (2025). Creatine monohydrate pilot in Alzheimer's: Feasibility, brain creatine, and cognition. Alzheimer's & dementia (New York, N. Y.), 11(2), e70101. https://doi.org/10.1002/trc2.70101Xu, C., Bi, S., Zhang, W., & Luo, L. (2024). The effects of creatine supplementation on cognitive function in adults: a systematic review and meta-analysis. Frontiers in nutrition, 11, 1424972. https://doi.org/10.3389/fnut.2024.1424972

Can AI and mass timber help solve the housing crisis? In this episode of Constructive, Seth sits down with Seyfihan Usarer — Co-Founder & COO of Algoma — to explore how their startup is transforming the slow, siloed preconstruction process into a fast, transparent decision engine for real estate developers.From feasibility studies powered by zoning-AI and comps to mass timber kits of parts, Seyf shares how Algoma is helping developers go from site to permit with clarity and speed — while keeping carbon footprint in check. They talk housing affordability, startup lessons from McKinsey and TikTok, and why the future of construction is an optimization game.

Send us a textConvergent's Jay Werth and Pam Reid discuss the importance of conducting a feasibility study before launching a capital or comprehensive campaign. Pam emphasizes that feasibility studies provide crucial intelligence for a case for investment development and informed decision-making. She also introduces the IMPACT acronym for case content: Introduction, Mission, Problem, Actual Impact, Call to Action, and Transparency. Pam advises that draft cases should be concise, visually appealing, and tailored to the audience. Curious why Comprehensive Campaigns are a game-changer for nonprofit fundraising? Sign up for updates!

POCUS Journal Podcast Episode 11:“Demonstrating Feasibility of Point of Care Ultrasound (POCUS)-Guided Inpatient Transthoracic Echo Triage Decision Pathway"Guests: Dr. Stephanie Connerand Dr. Mustafa HusainiGuest Editor: Dr. Ritu ThammanDOI: https://doi.org/10.24908/pocusj.v10i01.17776

This week on The Beat, CTSNet Editor-in-Chief Joel Dunning recaps the 33rd European Society of Thoracic Surgeons (ESTS) annual meeting in Budapest. Chapters 00:00 Intro 01:30 ESTS 2025 Conference 09:11 SHURUI Robot Study 10:04 Willard A. Fry 12:44 Transplant Recipient Pregnancy Outcomes 15:25 Low-Flow, Low-Gradient Aortic Stenosis 17:12 Warm Ischemic Intervals Effect 19:16 Extracorp Circulation vs Conventional 23:23 Femoral Cannulation for CPB Min Invasive 24:25 Valve Sparing Aortic Root Replacement 25:27 Valve Surgery Podcast w Michael Mack 27:21 Upcoming Events 27:54 Closing He discusses the key themes and takeaways from the event, the SHURUI single-port robotic system, the hands-on experience with the da Vinci Single-Port system led by Dr. Tom Routledge, and the extraordinary guest lecture from Ernő Rubik, the inventor of the Rubik's cube. Joel also highlights various presentations from the meeting, including “Does the Fissureless Technique Really Reduce Air Leak? Results of the Prospective Randomized Study Fissureless Versus Fissurefirst (3F Trial)” by Tom Routledge, “Tour D'Horizon About Potential Newcomings in the 10th Edition” by Valerie Rusch, and much more. Additionally, he pays tribute to Willard A. Fry and his significant accomplishments.   Joel also highlights recent JANS articles on pregnancy outcomes in 53 female lung transplant recipients, outcomes of surgical versus transcatheter aortic valve replacement in patients with low-flow, low-gradient aortic stenosis, the effect of warm ischemic intervals on primary graft dysfunction in normothermic regional perfusion for donation after circulatory death heart transplant, and minimal invasive extracorporeal circulation versus conventional cardiopulmonary bypass in cardiac surgery.  In addition, Joel explores femoral cannulation for CPB during minimally invasive cardiac surgery, a presentation from the Society for Cardiothoracic Surgery in Great Britain and Ireland annual meeting on “Valve Sparing Aortic Root Replacement—Tips and Tricks,” and the one-year anniversary episode of The Atrium podcast featuring host Dr. Alice Copperwheat speaking with cardiothoracic surgery pioneer Dr. Michael Mack on the future of valve surgery. Before closing, Joel highlights upcoming events in CT surgery.    JANS Items Mentioned  1.) Pregnancy Outcomes in 53 Female Lung Transplant Recipients  2.) Outcomes of Surgical Versus Transcatheter Aortic Valve Replacement in Patients With Low-Flow, Low-Gradient Aortic Stenosis  3.) The Effect of Warm Ischemic Intervals on Primary Graft Dysfunction in Normothermic Regional Perfusion for Donation After Circulatory Death Heart Transplant  4.) Minimal Invasive Extracorporeal Circulation Versus Conventional Cardiopulmonary Bypass in Cardiac Surgery: A Contemporary Systematic Review and Meta-Analysis  CTSNET Content Mentioned  1.) Femoral Cannulation for CPB During Minimally Invasive Cardiac Surgery  2.) SCTS 2025 | Valve Sparing Aortic Root Replacement—Tips and Tricks  3.) The Atrium: The Future of Valve Surgery  Other Items Mentioned  1.) Safety and Feasibility of Novel Single-Port Robotic-Assisted Lobectomy/Segmentectomy for Lung Cancer  2.) A Eulogy for Willard A. Fry  3.) 2025 SCTS Annual Meeting Videos   4.) The Atrium—All Episodes   5.) Career Center   6.) CTSNet Events Calendar  Disclaimer The information and views presented on CTSNet.org represent the views of the authors and contributors of the material and not of CTSNet. Please review our full disclaimer page here.

Summary In this episode of Develop This Podcast, Dennis Fraise interviews Brian Abernathy, General Manager of Convergent Nonprofit Solutions, discussing the importance of revenue benchmarking for Economic Development Organizations (EDOs). They explore how public-private partnerships have become best practices in funding, the methodology behind revenue benchmarking studies, and the significance of analyzing sector representation in funding sources. The conversation emphasizes the need for effective communication and long-term strategies in economic development. Takeaways Convergent specializes in fundraising planning and consulting for nonprofits. Revenue benchmarking helps EDOs understand their funding structure. Public-private partnerships enhance funding opportunities for EDOs. Data analysis reveals unique areas of opportunity for revenue. Diversity in funding sources is crucial for sustainability. Comparative analysis helps EDOs identify gaps in funding. The benchmarking process takes about four to six weeks. Effective communication builds trust with funders over time. Feasibility studies validate funding opportunities for EDOs. Long-term strategies are essential for successful economic development.

Interview with Walter Coles, Executive Chairman of Skeena Resources Ltd.Our previous interview: https://www.cruxinvestor.com/posts/skeena-resources-tsxske-fully-funded-high-grade-gold-poised-for-production-5657Recording date: 29th May 2025Skeena Gold & Silver is developing the Eskay Creek Mine in British Columbia, positioned to become one of the world's largest gold-silver mines when production begins in early 2027. This project represents a compelling investment opportunity with exceptional economics, significant upside potential, and multiple near-term catalysts that could drive substantial share price appreciation.The project's economics are truly remarkable. At $3,200/oz gold price, Eskay Creek boasts an after-tax NPV of $4.5 billion and an extraordinary 72% internal rate of return. This translates to a payback period of just over six months on the $700 million construction cost. Most impressively, Skeena's all-in sustainable cost per ounce is projected at less than $600 for the first six years of production, compared to approximately $1,700 for major producers like Barrick and Newmont. "We have a project that's super super low on the cost curve, enormously profitable per ounce of production.", explains Coles. This cost advantage creates exceptional profit margins even at much lower gold prices.Skeena has secured comprehensive financing through Orion Resource Partners, removing a major uncertainty that typically impacts junior developers. The $750 million package includes equity, a gold stream, and debt facilities. Since announcing this funding, Skeena's stock has nearly tripled from around $6 to $17 Canadian. The company is now exploring refinancing options to reduce its cost of capital as the project de-risks.Beyond the base case, Skeena is advancing several value-enhancement initiatives. The company plans to extend the mine life from 12 to 15-16 years by incorporating the high-grade Snip deposit and the Albino Lake waste facility. Additionally, Skeena has identified significant antimony, lead, and zinc content worth potentially 2.2 million tons of waste tailings that could be recovered with minimal additional costs.Investors can look forward to several near-term catalysts such as final permits expected in Q4 2025, refinancing of the Orion loan facility in Q1 2026, updated feasibility study in the first half of 2026, and production commencement in early 2027.Skeena's partnership with the Tahltan First Nation adds another layer of strength to the project. The company signed the first agreement in Canada giving a First Nation formal consent rights over a mining project, creating a true partnership that reduces social and political risk factors.For investors seeking exposure to precious metals with significant upside potential, Skeena offers a rare combination of exceptional grade, economics, and execution capability in a tier-one jurisdiction. As the company advances toward production and begins generating substantial cash flow, the valuation gap with producing peers is likely to close, potentially delivering substantial returns to investors who position themselves ahead of these developments.View Skeena Gold & Silver's company profile: https://www.cruxinvestor.com/companies/skeena-resourcesSign up for Crux Investor: https://cruxinvestor.com

Join our Patreon and get access to monthly bonus episodes and more nutriton content!Can fasting really slow aging? Does calorie restriction work for humans, or just for mice and yeast? And how much protein do you actually need to age well? This week on Your Diet Sucks, we break down the evidence behind the most talked-about interventions in the longevity space, what holds up under scrutiny, what doesn't, and why you might not need a supplement stack to live longer, and enjoy life. We dig into:The actual science on calorie restriction, fasting, and supplements—and where the evidence stopsWhat inflammation, oxidative stress, and telomeres have to do with how we ageThe best-researched dietary patterns for living longer (hint: it's not sexy, but it might include red wine)Why protein becomes more important as we ageThe difference between lifespan and healthspan, and why quality of life needs to be part of the conversation

The United States and China reached a 90-day truce in the trade war when their representatives met in Geneva in early May. Both sides agreed to temporarily roll back tariffs and non-tariff trade barriers. President Trump announced that a “total reset” in US-China relations had been achieved. Beyond the hyperbole, the two sides agreed to establish a mechanism on economics and trade and launch negotiations to address trade imbalances and other problems. Whether a deal is reached, what it might look like, and what it might include, remains to be seen. The future trajectory of US-China relations, overall, is still unclear.This episode highlights a Chinese perspective on the US-China bilateral relationship, including on the recent trade talks and the factors that will influence US-China relations going forward. Sun Chenghao, a fellow and head of the U.S.-Europe program at Tsinghua University's Center for International Security and Strategy (CISS), and council member of the Chinese Association of American Studies joins host Bonnie Glaser for this episode.  Timestamps[00:00] Start[01:39] What does Trump want from China? [04:29] What view does Dr. Sun hold?[05:00] Assessing the US-China Geneva Talks[09:21] Feasibility of a Broad US-China Trade Deal[13:23] Implications of Trump's “Unification” Comment[16:46] Importance of the Strategic Channel[20:47] Declining America, Rising China[23:27] Shift in US Policy Toward Alliances[27:49] The Future of US-China Relations

What makes a clinical trial site successful when managing complex transplant studies? In this episode of “Moving Medicine Forward,” host Jeremy Schrand is joined by Shawna Bredek, a 20+ year veteran in clinical trial operations, to explore how feasibility assessments shape the future of life-saving research. Shawna shares how her team evaluates sites, navigates post-COVID challenges, tackles regulatory hurdles, and builds lasting relationships that help bring rare disease treatments and transplant innovations to life. Whether you're working in clinical research or simply curious about medical breakthroughs, this episode offers a compelling look at the strategy behind meaningful science.  Show Notes: 00:36 Meet Shawna Bredeck, VP Global Site Activation & Clinical Document Management at CTI 00:52 Feasibility in the context of a clinical trial 01:18 Why choosing the right site and Private Investigator is critical 02:12 Post-COVID challenges: site fatigue, turnover, and timelines 03:34 Sponsors' expectations vs. site realities 04:03 Asking tough feasibility questions upfront 05:17 Transplant-specific logistics: 24/7 coverage and site readiness 05:54 Navigating regulatory red tape across countries 07:28 How regulatory delays can stall important trials 08:12 Global differences: why it's easier to start in Brazil than the US 08:54 Engaging rare disease sites through relationships and reputation 09:56 Partnering with advocacy groups for trial success 10:58 Shawna's proudest career moment: a major transplant drug approval 12:21 The human side of transplant research 12:50 The shared mission of patients, sponsors, sites, and scientists 13:02 Final thoughts and how to connect with CTI 

Here's how I can help you: Courses https://www.dickersoninternational.com/coursesMentorshiphttps://www.dickersoninternational.com/mentorshipConnect with me here: Facebook: https://www.facebook.com/pg/thegregdickersonInstagram: https://www.instagram.com/thegregdickersonLinkedIn: https://www.linkedin.com/in/agregdickersonTwitter: https://twitter.com/agregdickersonYouTube: https://www.youtube.com/user/agregdickerson/?sub_confirmation=1Podcast: https://www.dickersoninternational.com/podcast#realestatedevelopment #realestateinvesting #realestate Greg is a serial entrepreneur, real estate developer, coach and mentor to high level investors around the world. He has bought, developed and sold over $250 million in real estate, built and renovated hundreds of custom homes and commercial buildings, developed residential and mixed-use subdivisions and started 12 different companies from the ground up. Greg currently mentors some of the top entrepreneurs, real estate investors and real estate developers in the country helping them grow and scale their business, raise more capital and do bigger deals. Greg's current clients have over $2 billion in AUM and deals in the process.Greg is an expert on the topics of entrepreneurship, leadership and real estate and is regularly interviewed on some of the top real estate investing and business podcasts today.Greg served in the United States Navy right out of high school and has always been a leader in the community as well as supporting, advising and serving on the boards of several churches, ministries and non-profit organizations. This channel is all about Entrepreneurship, Real Estate Investing and Real Estate Development*Nothing in this video or podcast is meant to be construed as legal or investment advice, it's for entertainment purposes only. The video is accurate as of the posting date but may not be accurate in the future.WATCH OUT FOR SCAMMERS IN THE COMMENTS I do not have a telegram, discord or any tother type of paid group. I will not contact you here or on other platforms. Scammers are using my name and picture. My real profile has a dark background around my name. I will not ask you to contact me, ask you for money or give you any contact info. Do not contact anyone in the comments. PLEASE HELP BY REPORTING AND DELETING ALL THESE SCAMMERS. Thank you!

The practicalities of birthright citizenship being restricted in some states but not others appeared to be a concern of key justices on the US Supreme Court. President Donald Trump has asked the justices to narrow lower court rulings that blocked his executive order limiting automatic citizenship to babies born with at least one parent who's a citizen or permanent resident. Cases and Controversies hosts Greg Stohr and Lydia Wheeler discuss Thursday's arguments and highlight the exchanges that seemed to show the justices are wary of letting Trump start enforcing his restrictions. Do you have feedback on this episode of Cases and Controversies? Give us a call and leave a voicemail at 703-341-3690.

In this episode of Good Morning Liberty, hosts Nate Thurston and Chuck Thompson discuss President Trump's recent speech in Saudi Arabia, highlighting his comments on the Middle East's modernization and peace through negotiation. They also delve into a new book by Jake Tapper and Alex Thompson that reveals concerns about Joe Biden's cognitive decline during his presidency, and discuss the implications of lifting sanctions on Syria. The episode also touches on the role of the media in shaping public perception and foreshadows an upcoming analysis on a new spending bill. (00:00) Introduction (01:25) Trump's Speech and Biden's Mental Decline (03:37) Discussion on Trump's Foreign Policy (07:29) Syria Sanctions and Middle East Diplomacy (18:05) Trump's Speech Highlights (29:28) Interactive Segment and Closing Remarks (30:20) Discussing the Feasibility of Continuing the Podcast (31:04) Introducing the Biden Book Controversy (33:05) Media's Role in Biden's Decline (36:07) Reactions to the Book's Revelations (39:00) Jake Tapper's Involvement and Media Critique (42:32) The White House's Deception and Media's Complicity (49:48) The Future of Media and Political Transparency   Links:   https://gml.bio.link/   YOUTUBE:   https://bit.ly/3UwsRiv   RUMBLE:   https://rumble.com/c/GML   Check out Martens Minute!   https://martensminute.podbean.com/   Follow Josh Martens on X:   https://twitter.com/joshmartens13   Join the private discord & chat during the show!   joingml.com   Bank on Yourself bankonyourself.com/gml   Get FACTOR Today! FACTORMEALS.com/factorpodcast     Good Morning Liberty is sponsored by BetterHelp! Rediscover your curiosity today by visiting Betterhelp.com/GML (Get 10% off your first month)     Protect your privacy and unlock the full potential of your streaming services with ExpressVPN. Get 3 more months absolutely FREE by using our link EXPRESSVPN.com/GML  

We're looking at the proposals for a new line connecting the North Wales Main Line and the Cambrian Coast Line between Bangor and Afon Wen... Are the plans any good? Should they go ahead even if the correct route for a north-south Welsh mainline is at the other side of the country? Way back in Episode 57 we analysed where any future north-south Welsh railway needed to be, and we fleshed those plans out into the Dragon Line/Llinell Y Ddraig in Episode 116. Let's see how this report aligns with that - or doesn't. Download the report here: https://www.gov.wales/sites/default/files/publications/2025-02/re-opening-the-bangor-to-afon-wen-rail-line-feasibility-study.pdf Enjoyed this? Please do consider supporting #Railnatter at https://patreon.com/garethdennis or throw loose change at me via https://paypal.me/garethdennis. Merch at https://garethdennis.co.uk/merch. Join in the discussion at https://garethdennis.co.uk/discord. You can also buy my book #HowTheRailwaysWillFixTheFuture: https://bit.ly/HowTheRailways

In this episode of the California Underground Podcast, hosts Phil and Camille discuss significant political developments in California, focusing on the controversial AB 379 bill aimed at protecting minors from sexual exploitation. They explore Trump's proposal to reopen Alcatraz, the historical context of the prison, as well as hypocritical Democratic politicians like Ted Lieu who claim to be Catholic, yet support ideals that go against Catholic teachings. Are you a Californian who feels isolated and alone in your political views in a deep blue state? Feel like you can't talk about insane taxes, an overbearing government, and radical social experiments without getting a side eye? Then join us on the California Underground Podcast, the most trusted podcast on all things California politics.Original air date  5.6.25*The California Underground Podcast is dedicated to discussing California politics from a place of sanity and rationality.*Chapters04:58 Discussion on Trump's AI Pope Image and Ted Lieu's Reaction11:00 Hypocrisy in Political Statements Regarding Catholicism19:06 Trump's Proposal to Reopen Alcatraz27:19 Exploring the Feasibility of Reopening Alcatraz31:30 In-Depth Analysis of AB 379 and Its Implications37:08 Debating the Age of Consent and Trafficking Laws44:01 Heated Assembly Floor Discussions50:55 The Impact of Public Pressure on Legislation01:01:59 Political Maneuvering and Accountability01:13:35 The Importance of Civic EngagementCheck out our full site for more information about the show at www.californiaunderground.liveCheck out our sponsor for this episode, StopBox, by going to www.stopbox.com/californiaunderground to get 10% off your orderFollow California Underground on Social Media  Instagram: www.instagram.com/californiaunderground X: https://twitter.com/CAUndergoundTik Tok: https://www.tiktok.com/@californiaunderground?_t=8o6HWHcJ1CM&_r=1YouTube: https://www.youtube.com/channel/UCj8SabIcF4AKqEVFsLmo1jA Read about our Privacy Policy: https://www.spotify.com/us/legal/privacy-policy/ 

Dr. Ezra Schwartz (@ezraschwartz10) interviews Dr. Firas Moussa and Mr. Jake Howitt to discuss the IMPROVE-AD Trial, a landmark, multi-institutional study investigating treatment strategies for uncomplicated Type B Aortic Dissection (uTBAD). The IMPROVE-AD Trial is a multicenter randomized trial funded by the NIH/NHLBI that compares thoracic endovascular aortic repair (TEVAR) plus optimal medical therapy (OMT) vs. OMT and surveillance with selective TEVAR in patients with uncomplicated TBAD. The trial aims to address critical gaps in evidence left by prior studies (INSTEAD-XL, ADSORB), with a unique focus on quality of life, cost-effectiveness, and genetic data. Dr. Firas Mussa is a professor and the Chief of Vascular and Endovascular Surgery at McGovern Medical School at UTHealth Houston. He previously served as the Director of the Vascular Surgery Residency and Fellowship programs at NYU Langone Health. Dr. Mussa earned his medical degree from the University of Baghdad, followed by general surgery training at Johns Hopkins University and a vascular surgery fellowship at Baylor College of Medicine. His research focuses on complex aortic pathology, and he serves as the principal investigator of the IMPROVE AD trial. Mr. Jake Howitt is the Community Engagement Co-Chair of the IMPROVE AD trial and a leading patient advocate within the PCORI-funded Aortic Dissection Collaborative. As a survivor of aortic dissection, he is passionate about improving patient-provider communication and raising awareness of hereditary aortic disease. His work emphasizes the importance of education, empathy, and community-building in clinical research and care delivery. Special thank you to Jacob Soucy (@JacobWSoucy). Resources: ·       Treatment of Uncomplicated Type B Aortic Dissection: Optimal Medical Therapy vs TEVAR + Optimal Medical Therapy- https://journals.sagepub.com/doi/10.1177/15385744231184671?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed  ·       INSTEAD Trial - https://pubmed.ncbi.nlm.nih.gov/19996018/ ·       INSTEAD-XL 5-Year Follow-Up - https://pubmed.ncbi.nlm.nih.gov/23922146/ ·       ADSORB Trial - https://pubmed.ncbi.nlm.nih.gov/24962744/ ·       Feasibility of a proposed randomized trial in patients with uncomplicated descending thoracic aortic dissection: Results of worldwide survey - https://pubmed.ncbi.nlm.nih.gov/27823685/ ·       Treatment of AD: Meta-Analysis - https://pubmed.ncbi.nlm.nih.gov/29066151/ ·       TEVAR vs Medical Therapy- https://pubmed.ncbi.nlm.nih.gov/36334259/ ·       IMPROVE AD Trial website - https://improvead.org ·       John Ritter Foundation for Aortic Health - https://johnritterfoundation.org ·       Think Aorta US - https://thinkaorta.us   Follow us @audiblebleeding Learn more about us at https://www.audiblebleeding.com/about-1/ and provide us with your feedback with our listener survey.  *Gore is a financial sponsor of this podcast, which has been independently developed by the presenters and does not constitute medical advice from Gore. Always consult the Instructions for Use (IFU) prior to using any medical device.      

“Everyone's brain is extremely heterogenic, so it's different. You can put five of us in a room; we can all have the same diagnosis of a [glioblastoma multiforme], but all of ours can be different. They're highly aggressive biologically. It's a small area in a hard shell. So trying to get through the blood–brain barrier is different. There's a lot of areas of hypoxia in the brain. There's a lot of pressure there. The microbiology is very different—it's a cold environment versus a hot environment—and then the pathways are just different,” Lori Cappello, MSN, APN-C, CCRP, research advanced practice nurse at the John Theurer Cancer Center of Hackensack Meridian Health in New Jersey, told Jaime Weimer, MSN, RN, AGCNS-BS, AOCNS®, manager of oncology nursing practice at ONS, during a conversation about brain malignancies and caring for patients with them. Music Credit: “Fireflies and Stardust” by Kevin MacLeod Licensed under Creative Commons by Attribution 3.0  Earn 0.5 contact hours of nursing continuing professional development (NCPD) by listening to the full recording and completing an evaluation at courses.ons.org by April 25, 2027. The planners and faculty for this episode have no relevant financial relationships with ineligible companies to disclose. ONS is accredited as a provider of nursing continuing professional development by the American Nurses Credentialing Center's Commission on Accreditation. Learning outcome: Learners will report an increase in knowledge related to brain malignancies and their diagnosis and treatment. Episode Notes  Complete this evaluation for free NCPD.  ONS Podcast™ episodes: Episode 235: Self-Advocacy Skills for Patients Episode 166: Cognitive Behavioral Interventions Help Patients With a Spectrum of Cancer Symptoms ONS Voice articles: Glioblastoma Diagnosis, Treatment, Side Effect Management, and Survivorship Recommendations Blocking Fatty Acid Storage May Induce Glioblastoma Apoptosis Brain Tumor Navigator Role Bridges the Intersection of Cancer and Neuroscience Researchers Tie More Cancers, Mortality to NF1 Disorders Larotrectinib and Other Tumor-Agnostic Targeted Therapies Are Leading Cancer Care Into the Next Frontier McCain Announcement Sheds Light on Nurses' Role in Advance Care Planning ONS book: Manual for Radiation Oncology Nursing Practice and Education (fifth edition) Clinical Journal of Oncology Nursing articles: Implementing a Standardized Educational Tool for Patients With Brain Tumors Undergoing Concurrent Temozolomide and Radiation Therapy Exercise Intervention: A Pilot Study to Assess the Feasibility and Impact on Cancer-Related Fatigue and Quality of Life Among Patients With High-Grade Glioma Society for Neuro-Oncology Musella Foundation End Brain Cancer Initiative Brain Tumor Network American Brain Tumor Association Glioblastoma Research Organization Brain Tumor Funders' Collaborative Optune Gio® website Nurse.org article: Mysterious Brain Tumor Cluster Grows: Another Nurse Diagnosed at Newton-Wellesley Lori Cappello's contact information: lori.cappello@hmhn.org To discuss the information in this episode with other oncology nurses, visit the ONS Communities. To find resources for creating an ONS Podcast Club in your chapter or nursing community, visit the ONS Podcast Library. To provide feedback or otherwise reach ONS about the podcast, email pubONSVoice@ons.org. Highlights From This Episode “A glioblastoma actually is the most predominant brain tumor that we do see. It is the most diagnosed of the brain tumors. And then I would say that an anaplastic astrocytoma is probably the second diagnosed. Historically a GBM, they used to say was probably an elderly patient for these. But we are definitely seeing it diagnosed at a much younger age now, definitely much more prevalent for people under 60.” TS 3:17 “Nine times out of ten, either a patient out of nowhere has a seizure, or they present with what they think are stroke-like symptoms. They noticed that they were slurring, or they were becoming more forgetful, or a family member noticed it and said, ‘Hey, what is going on with you?' But usually they present to the [emergency department], and a [computed tomography] scan is always done first. And lo and behold, something is seen.” TS 4:50 “The only other U.S. Food and Drug Administration-approved treatment that has come along in the last 20 years is a device called Optune Gio, which is an alternating electric field that stops cell division at the mitosis stage.” TS 7:45 “They lose so much of their independence, especially if they don't have a caregiver or help. That is huge. Medication management at home, to making sure that they're taking the medication properly, that they are actually taking their medication. Transportation is another huge problem. Getting to and from appointments is a challenge. Those are big issues—real, day-to-day, simple issues that people don't think about.” TS 17:11 “I think that having a brain tumor is very unique in the fact that you really need a dedicated neuro-oncologist. And depending on where you live, there are not a lot in the area. I actually had a patient that was moving out west, and the closest dedicated neuro-oncologist was four hours from them. … if you're not seeing dedicated neuro oncologists, you might not be getting the best treatment for yourself. So I think that having the resources and helping patients find the best care or the best brain tumor society—and there's a bunch of really good brain tumor groups to help patients find the best resources out there. I think that's really, really important for patients to know or for families to know.” TS 19:17 “So trying to help patients, there are always going to be challenges, and there are always going to be ups and downs. But finding that one person that they can go to, that they trust, that they have a great relationship with, whether at the doctor's office or whatever, and being available to them makes such a difference in their journey. I think that that is the most important for anybody in the journey.” TS 22:08 “With brain, there are going to be expectations. They are going to lose functionality at some point—and preparing them for that thing or preparing them for things that can help themselves. Like sometimes I say, ‘Go to the dollar store, get coloring books,' if they have weakness in one hand. Little tricks of the trade that can help them. About treatment options, going through the side effects, preparing them for whatever they can be prepared for.” TS 22:39 “It is not one of the better cancers to have, but it doesn't immediately mean it's a death sentence, and we shouldn't treat them like they're dying. We shouldn't take away their ability to live just because they were diagnosed with it. We shouldn't take away hope.” TS 25:35 “I think there's not enough discussed about [brain malignancies] and the lack of resources for this. These patients need a lot more resources and are available. There's just not enough available for it.” TS 26:59

Feasibility and acceptability of a six-month exercise and patient education intervention for patients with hip dysplasia: A mixed methods study Jacobsen JS, Thorborg K, Sørensen D, et al. Musculoskelet Sci Pract. 2022;61:102615. doi:10.1016/j.msksp.2022.102615 Due to copyright laws, unless the article is open source we cannot legally post the PDF on the website for the world to download at will. Brought to you by our sponsors at: CSMi – https://www.humacnorm.com/ptinquest Learn more about/Buy Erik/Jason/Chris's courses – The Science PT Support us on the Patreons! Music for PT Inquest: “The Science of Selling Yourself Short” by Less Than Jake Used by Permission Other Music by Kevin MacLeod – incompetech.com: MidRoll Promo – Mining by Moonlight Koal Challenge – Sam Roux

In this episode, we sit down once again with Bill Willoughby, CEO of Century Lithium (TSXV: LCE.V, OTCQX: CYDVF), to discuss the latest developments at their Nevada-based lithium project, Angel Island. We cover the company's unique chlor-alkali processing method, recent optimization studies, and the impact of the U.S. government's executive order to accelerate domestic mineral production. Bill shares insights on Century's permitting progress, strategic partnerships, and the potential for significant CAPEX reductions. CHAPTERS

People with aphasia can have problems understanding or using numbers in everyday life - known as functional numeracy difficulties. However, testing this is hard because there are limited published assessments for functional numeracy difficulties for people with aphasia. This study aimed to explore, validate and pilot a wide-ranging, aphasia-friendly functional numeracy assessment to investigate how functional numeracy is impacted by aphasia severity and time pressure demands, and to explore predictors of PWA's functional numeracy.The paper is:Which blueberries are better value? The development and validation of the functional numeracy assessment for adults with aphasia' https://onlinelibrary.wiley.com/doi/full/10.1111/1460-6984.12867 Kerri Ichikowitz, Carolyn Bruce, Vanessa Meitanis, Kelly Cheung, Yekyung Kim, Esther Talbourdet, Caroline NewtonFirst published: 13 March 2023This paper was awarded the IJLCD student prize.Resources:If you would like access to the online version of the Functional Numeracy Assessment, please contact the study authors.The intervention study: Newton, C., Meitanis, V., Bruce, C., & Donlan, C. (2025). Evaluation of the SWAN game-based approach to re-building numeracy skills in aphasia: Feasibility and preliminary findings. https://doi.org/10.31234/osf.io/f7d39_v1 The survey of SLTs: Newton, C., Brancamp, D., & Brancamp, T. (2025). The rehabilitation of numerical processing and calculation in aphasia: An international survey of speech-language pathologists. https://doi.org/10.31234/osf.io/g63j9_v1 Please be aware that the views expressed are those of the guests and not the RCSLT.Please do take a few moments to respond to our podcast survey: uk.surveymonkey.com/r/LG5HC3R

For the first time, in a long time, more breweries are closing than opening. One of the success factors for breweries that survive and thrive vs. those who do not, is a feasibility study. Jon Reynolds from Brew Plan Marketing specializes in feasibility studies, market research, and data gathering. In today's podcast, Jon shares trends, growth areas, and the details of how to build a feasibility study for brewery success.  Summary What a feasibility study is and why it's important7 benefits of market analysisResource run-down of brewery data to make informed decisionsResourcesConnect with Jon Reynolds from BrewPlan Marketing, brewplanmarketing@gmail.comGrab the FREE brewery financial planning newsletter

In this episode, we speak with Matteo Mirolo, Director of Strategy & External Relations at Contrails.org, a science-led nonprofit initiative aimed at transforming contrail research into practical climate action. Mirolo discusses:The substantial climate impact of contrails, which are responsible for 1-2% of human-caused global warming and have roughly the same warming effect as all aviation CO2 emissions since the jet age.The concentrated nature of the problem, with just 5% of flights causing about 80% of aviation's contrail warming effect, primarily over Europe, North America, and the North Atlantic.Contrails.org's three-pillar approach focusing on science (improving understanding of contrail impacts), technology (developing open-source tools and protocols), and adoption (raising awareness and fostering incentives).The cost-effectiveness of contrail mitigation compared to other decarbonisation options, with studies suggesting only 0.11% extra fuel burn across airline fleets.The vision for seamless integration into airline operations, where contrail avoidance becomes as routine as avoiding turbulence or adverse weather.Contrails.org seeks to be an open, collaborative space, with Mirolo likening it to “a tent under which people can put their furniture.” Its goal is to address the contrail issue through collective effort, recognising that effective management requires coordination across the aviation sector.If you LOVED this episode, you'll also love the conversation we had with Alejandra Martín Frías, Head of Sustainability Research at FLIGHTKEYS, who shared insights into the company's research on contrail avoidance. Check it out here. Learn more about the innovators who are navigating the industry's challenges to make sustainable aviation a reality, in our new book ‘Sustainability in the Air'. Click here to learn more.Feel free to reach out via email to podcast@simpliflying.com. For more content on sustainable aviation, visit our website green.simpliflying.com and join the movement. It's about time.Links & More:Contrails.orgHow airplane contrails are helping make the planet warmer - Yale e360 Feasibility of contrail avoidance in a commercial flight planning system: an operational analysis - IOPscience Understanding contrail management: opportunities, challenges, and insights - RMIThis episode is brought to you by 4AIR. 4AIR is leading the way with the industry's first framework to address aviation's climate impact—offering clear, verifiable pathways to reduce and counteract aircraft emissions. For more information, please visit: https://www.4air.aero/

Notes from James: What if I told you that we could eliminate the IRS, get rid of personal income taxes completely, and still keep the government funded? Sounds impossible, right? Well, not only is it possible, but historical precedent shows it has been done before. I know what you're thinking—this sounds insane. But bear with me. The IRS collects $2.5 trillion in personal income taxes each year. But what if we could replace that with a national sales tax that adjusts based on what you buy? Under my plan: Necessities (food, rent, utilities) 5% tax Standard goods (clothes, furniture, tech) 15% tax Luxury goods (yachts, private jets, Rolls Royces) 50% tax And boom—we don't need personal income taxes anymore! You keep 100% of what you make, the economy booms, and the government still gets funded. This episode is a deep dive into how this could work, why it's better than a flat tax, and why no one in government will actually do this (but should). Let me know what you think—and if you agree, share this with a friend (or send it to Trump). Episode Description: What if you never had to pay personal income taxes again? In this mind-bending episode of The James Altucher Show, James tackles a radical idea buzzing from Trump, Elon Musk, and Howard Lutnick: eliminating the IRS. With $2.5 trillion in personal income taxes on the line, is it even possible? James says yes—and he's got a plan. Digging into history, economics, and a little-known concept called “money velocity,” James breaks down how the U.S. thrived in the 1800s without income taxes, relying on tariffs and “vice taxes” on liquor and tobacco. Fast forward to today: the government rakes in $4.9 trillion annually, but spends $6.7 trillion, leaving a gaping deficit. So how do you ditch the IRS without sinking the ship? James unveils his bold solution: a progressive national sales tax—5% on necessities like food, 15% on everyday goods like clothes, and a hefty 50% on luxury items like yachts and Rolls Royces. Seniors and those on Social Security? They'd pay nothing. The result? The government still nets $2.5 trillion, the economy grows by $3.7 trillion thanks to unleashed consumer spending, and you keep more of your hard-earned cash. No audits, no accountants, just taxes at the cash register. From debunking inflation fears to explaining why this could shrink the $36 trillion national debt, James makes a compelling case for a tax revolution. He even teases future episodes on tariffs and why a little debt might not be the enemy. Whether you're a skeptic or ready to tweet this to Trump, this episode will change how you see taxes—and the economy—forever. What You'll Learn: The history of taxes in America—and how the country thrived without an income tax in the 1800s Why the IRS exists and how it raises $2.5 trillion in personal income taxes every year How eliminating income taxes would boost the economy by $3.75 trillion annually My radical solution: a progressive national sales tax—and how it works Why this plan would actually put more money in your pocket Would prices skyrocket? No. Here's why. Timestamps: 00:00 Introduction: Trump's Plan to Eliminate the IRS 00:22 Podcast Introduction: The James Altucher Show 00:47 The Feasibility of Eliminating the IRS 01:27 Historical Context: How the US Raised Money in the 1800s 03:41 The Birth of Federal Income Tax 07:39 The Concept of Money Velocity 15:44 Proposing a Progressive Sales Tax 22:16 Conclusion: Benefits of...

Jacob welcomes Tomas back onto the podcast in the wake of China's announcement that licences will now be required to export 20 tungsten, tellurium, bismuth, indium and molybdenum-related products to "safeguard national security interests.” Tomas and Jacob talk about how to align government priorities to secure access to materials and the complexities around building capacity in a deglobalizing world where demand for materials has literally never been more intense.--Timestamps:(00:00) – Intro (05:25) – Government priorities(11:12) – China and critical minerals(21:32) – Economics of mineral refining(31:27)– Social license to operate(38:19) – Feasibility of climate friendly goals(43:34) – Aluminum and REE case studies(52:35) – Food for thought--Jacob Shapiro Site: jacobshapiro.comJacob Twitter: x.com/JacobShapCI Site: cognitive.investmentsSubscribe to the Newsletter: bit.ly/weekly-sitrep--The Jacob Shapiro Show is produced and edited by Audiographies LLC. More information at audiographies.com --Jacob Shapiro is a speaker, consultant, author, and researcher covering global politics and affairs, economics, markets, technology, history, and culture. He speaks to audiences of all sizes around the world, helps global multinationals make strategic decisions about political risks and opportunities, and works directly with investors to grow and protect their assets in today's volatile global environment. His insights help audiences across industries like finance, agriculture, and energy make sense of the world.Cognitive Investments is an investment advisory firm, founded in 2019 that provides clients with a nuanced array of financial planning, investment advisory and wealth management services. We aim to grow both our clients' material wealth (i.e. their existing financial assets) and their human wealth (i.e. their ability to make good strategic decisions for their business, family, and career).--This podcast uses the following third-party services for analysis: Podtrac - https://analytics.podtrac.com/privacy-policy-gdrp

Testing a Mobile Mindful Eating Intervention Targeting Craving-Related Eating: Feasibility and Proof of ConceptIn this episode, Dr. Jud Brewer and colleagues discuss the results of a groundbreaking study testing a smartphone-based mindful eating intervention. Designed to target craving-related eating through mindfulness and operant conditioning principles, the intervention demonstrated significant reductions in food cravings, emotional eating, and overeating among overweight and obese women. Dr. Brewer explores how this scalable, low-burden approach leverages awareness to disrupt habitual eating patterns, reduce cravings, and support sustainable weight management. Tune in to learn how mobile mindfulness tools can reshape eating behaviors and promote healthier relationships with food.Full Reference:Mason, A. E., Jhaveri, K., Cohn, M., & Brewer, J. A. (2017). Testing a mobile mindful eating intervention targeting craving-related eating: Feasibility and proof of concept. Journal of Behavioral Medicine. https://doi.org/10.1007/s10865-017-9884-5Let's connect on Instagram

In this episode of NucleCast, Adam welcomes Chris Stone to discuss the recent executive order regarding the Iron Dome for America . They explore the implications of the order, the differences between the Israeli Iron Dome and the proposed American system, and the feasibility of developing a comprehensive missile defense system. The conversation also delves into budget considerations, the role of space in national defense, and innovative approaches to missile defense, emphasizing the urgency of addressing vulnerabilities in the face of emerging threats.Christopher Stone is a prominent figure in space policy, currently serving as a Senior Fellow for Space Deterrence at the National Institute for Deterrence Studies, where he focuses on research related to space warfare strategies and deterrence, particularly in the context of great power competition; he previously held a position as a Special Assistant to the Deputy Assistant Secretary of Defense for Space Policy at the Pentagon, giving him significant experience in the field of U.S. space policy development at a high level.Chapters00:00 Introduction to Iron Dome for America03:13 Understanding the Executive Order05:52 Comparing Iron Dome Systems: Israel vs. America09:08 Feasibility of Building a Comprehensive Defense System11:51 Budget Considerations and Strategic Implications15:01 The Role of Space in National Defense18:05 Innovative Approaches to Missile Defense20:55 The Future of Space-Based Interceptors23:55 Final Thoughts and Call to ActionSocials:Follow on Twitter at @NucleCastFollow on LinkedIn: https://linkedin.com/company/nuclecastpodcastSubscribe RSS Feed: https://rss.com/podcasts/nuclecast-podcast/Rate: https://podcasts.apple.com/us/podcast/nuclecast/id1644921278Email comments and topic/guest suggestions to NucleCast@anwadeter.org

ThunderClan deals with the aftermath of battle - and starts to consider what the sun going out could mean.Book: Warriors, Series 3: Power of Three #4: EclipseSupport us on Ko-fi!WCWITCast Ko-fiFollow us on BlueSky!WCWITCastFollow us on Instagram!WCWITCast What We Are Reading (Not Sponsored):Escape From St Hell: My Trans Life Levels Up by Lewis Hancox Cat Fact Sources:Researchers put little hats on cats to measure their brainwaves | Popular ScienceNon-invasive electroencephalography in awake cats: Feasibility and application to sensory processing in chronic pain - ScienceDirectYoutube - Narby Pompom Cat Hat - Catventurous CrochetCat scans: Canadian scientists found an adorable new way to study cat brain activityOsteoarthritis in Cats: More Common Than You Think | FDAOsteoarthritis in Cats - American College of Veterinary SurgeonsResearchers Use Tiny Crochet Hats to Investigate Chronic Pain in CatsMusic:The following music was used for this media project:Happy Boy Theme by Kevin MacLeod Link: https://incompetech.filmmusic.io/song/3855-happy-boy-themeLicense:http://creativecommons.org/licenses/by/4.0/

In this week's episode of the Coin Stories News Block, we cover these major headlines related to Bitcoin and global finance: Trump Signs Order to Create U.S. Sovereign Wealth Fund David Sacks: “Stablecoins Could Lower Long-term Rates” Czech Republic Ends Capital Gains Tax on Bitcoin FDIC to Update Crypto Banking Guidelines and more! ---- Join my mailing list and subscribe to our free newsletter: thenewsblock.substack.com  ---- Natalie's Promotional Links:  Coin Stories is powered by Genius Group (NYSE American $GNS). Genius is a Bitcoin-first business delivering AI powered, education and acceleration solutions for the future of work. Learn more at https://www.geniusgroup.ai/btc-newsletter. Secure your Bitcoin with collaborative custody and set up your inheritance plan with Casa: https://www.casa.io/natalie  For easy, low-cost, instant Bitcoin payments, I use Speed Lightning Wallet. Get 5000 sats when you download using this link and promo code COINSTORIES10: https://www.speed.app/sweepstakes-promocode/ River is where I DCA weekly and buy Bitcoin with the lowest fees in the industry: https://partner.river.com/natalie  Safely self-custody your Bitcoin with Coinkite and the ColdCard Wallet. Get 5% off: https://store.coinkite.com/promo/COINSTORIES Master your Bitcoin self-custody with 1-on-1 help and gain peace of mind with the help of The Bitcoin Way: https://www.thebitcoinway.com/natalie Bitcoin 2025 is heading to Las Vegas May 27-29th! Join me for my 4th Annual Women of Bitcoin Brunch! Get 10% off Early Bird passes using the code HODL: https://tickets.b.tc/affiliate/hodl/event/bitcoin-2025   Protect yourself from SIM Swaps that can hack your accounts and steal your Bitcoin. Join America's most secure mobile service, trusted by CEOs, VIPs and top corporations: https://www.efani.com/natalie  Connect with Bitcoiners and Bitcoin merchants wherever you live and travel on the Orange Pill App: https://signup.theorangepillapp.com/opa/natbrunell ---- References mentioned in the episode:  Trump Executive Order to Create Soveriegn Wealth Fund Trump Signs Order to Create Sovereign Wealth Fund  Howard Lutnick Personally Owns A Lot of Bitcoin  Cantor Fitzgerald Announces Bitcoin Financing Business David Sacks Studying the Feasibility of Bitcoin Reserve  Senator Bill Hagerty's New Stablecoin Bill  Senator Hagerty Announces New Stablecoin Bill  David Sacks' Comments on Stablecoin Legislation Tether's Q4 2024 Attestation Paolo Ardoino Says Tether Won't Hold Long-duration  Bessent Says Focus On Lowering 10-Year Treasury Yields Czech Republic Eliminates Taxes on Bitcoin  Breez Report on the State of Bitcoin Payments  FDIC Releases Correspondence on Operation Chokepoint FDIC Set to Revise Guidelines for Banks on Digital Assets Hester Peirce's Policy Statement on Cryptocurrencies  Tiger 21 CEO Says It Holds $6 Billion in Digital Assets  MicroStrategy Rebrands to Strategy  Trump's Media Company to Launch Bitcoin ETF ARK Invest's Big Ideas 2025 Report ---- This podcast is for educational purposes and should not be construed as official investment advice. ---- VALUE FOR VALUE — SUPPORT NATALIE'S SHOWS Strike ID https://strike.me/coinstoriesnat/ Cash App $CoinStories   #money #Bitcoin #investing

Interview with Daniel Major, CEO of GoviEx Uranium Inc.Our previous interview: https://www.cruxinvestor.com/posts/goviex-uranium-tsxvgxu-positioning-for-production-in-2028-5872Recording date: 29th January 2025Goviex Uranium (TSXV: GXU) presents a timely opportunity for investors to gain exposure to the next uranium bull market through its flagship Muntanga project in Zambia. With a recently completed bankable feasibility study (BFS) demonstrating robust project economics, Goviex is well-positioned to bring a significant new source of uranium production online just as the market is projected to swing into a widening supply deficit.The Muntanga BFS, released in January 2025, confirms the viability of a large-scale, low-cost, open-pit uranium mining operation. The study outlines a straightforward mining and processing plan, utilizing conventional open pit truck and shovel mining to feed an on-off heap leach circuit. Muntanga benefits from several key advantages that contribute to its strong economic profile:High-grade, near-surface mineralization hosted in soft, porous sandstones allows for low-strip-ratio mining and coarse crushing to a P80 of 25 millimeters. This reduces mining and processing costs compared to many other uranium projects.The on-off heap leach process achieves quick leach cycles and high recoveries exceeding 90%, further enhancing project economics. The leach circuit has been designed to handle Zambia's seasonal rainfall patterns, with multiple pads to optimize loading, leaching, rinsing, and unloading cycles.Ready access to key infrastructure, including roads, water, and hydroelectric power, streamlines project development and reduces initial capital costs. Goviex can focus its efforts and capital on the core mining and processing facilities.Mining permits have already been secured, significantly de-risking the project. The company expects to receive final environmental approvals within 6 months of submitting its environmental and social impact assessment, which is planned for the end of Q1 2023.Strong local community support provides Goviex with a social license to operate. The company is working closely with local stakeholders to implement a fair and equitable relocation plan for a small number of households, with the aim of maximizing employment and economic development opportunities for the wider community.With a robust BFS in hand, Goviex is now shifting its focus to securing project financing and long-term offtake agreements. The company is seeing strong interest from lenders, particularly South African banks that have recently returned to mining finance. Goviex is pursuing a mix of debt and equity financing, with the aim of minimizing dilution while maintaining a conservative capital structure.On the offtake front, Goviex is leveraging its relationships with global nuclear utilities to negotiate long-term contracts with pricing that reflects the emerging supply deficit in the uranium market. The company is taking a flexible approach to contracting, with a willingness to commit a portion of its production to market-related pricing mechanisms that provide exposure to rising spot prices.For investors, Goviex presents a compelling opportunity to gain leveraged exposure to the next leg up in the uranium market cycle. With a large, low-cost, advanced-stage project in a mining-friendly jurisdiction, Goviex is well-positioned to become a leading supplier of uranium as demand from nuclear energy grows. While risks remain, particularly around securing financing in a challenging market environment, the potential rewards for investors who position themselves ahead of the next uranium bull market are substantial.In conclusion, Goviex Uranium offers investors a unique opportunity to participate in the development of a world-class uranium deposit just as the market is poised for a significant upturn. With a strong project economics, an experienced management team, and a clear path to production, Goviex is a company to watch in the uranium space.—View GoviEx Uranium's company profile: https://www.cruxinvestor.com/companies/goviex-uraniumSign up for Crux Investor: https://cruxinvestor.com

Welcome to a new episode of Business Lunch! In this episode, Roland Frasier and Ryan Deiss discuss Elon Musk's unique approach to problem-solving, where he reportedly solves his companies' biggest problems in a matter of weeks. They analyze the pros and cons of Musk's leadership style, including his willingness to make tough decisions and the potential impact on employees. The hosts also explore whether this approach can be replicated by other business leaders.Highlights:"He just came in there and went just ape, you know, and kind of gutted everybody who was essentially middle management.""The fundamental job, the single most important job that any CEO has, is determining what is the company's right next thing.""I do love the idea of saying, like, we are going to solve this problem in weeks, to say that every single thing that is our biggest problem can always be solved in a singular week.""If you're a leader, and if you decide that you're going to take on the role of solving a particular problem in your team, I don't think that's necessarily a bad thing, because, frankly, your people probably are above full capacity already."Timestamps:00:00 - Elon Musk's Approach to Problem-Solving01:20 - Musk's Ability to Solve Problems Quickly03:08 - Identifying the Real Problem07:03 - Feasibility of Musk's Approach09:01 -Downsides of Musk's "Demon Mode"12:38 - The CEO's Role in Determining the Right Next Thing13:40 - Shortening the Unit of Measurement15:00 - Empowering Middle Management20:00 - Communicating the Problem-Solving Approach26:35 - The Sustainability of Elon Musk's ApproachCONNECT • Ask Roland a question HERE.RESOURCES:• 7 Steps to Scalable workbook • Get my book, Zero Down, FREETo learn more about Roland Frasier

Send us a textFeasibility and safety of autologous cord blood derived cell administration in extremely preterm infants: a single-centre, open-label, single-arm, phase I trial (CORD-SaFe study).Zhou L, McDonald CA, Yawno T, Razak A, Connelly K, Novak I, Miller SL, Jenkin G, Malhotra A.EBioMedicine. 2024 Dec 13;111:105492. doi: 10.1016/j.ebiom.2024.105492. Online ahead of print.PMID: 39674685 Free article.As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter's Weekly Newsletter Dr. Saum Sutaria is the Chairman and CEO of Tenet Healthcare and a former leader in McKinsey & Company's Healthcare and Private Equity Practices, where he spent almost two decades shaping the field. In this episode, Saum unpacks the complexities of the U.S. healthcare system, providing a detailed overview of its structure, financial flows, and historical evolution. They delve into topics such as private insurance, Medicare, Medicaid, employer-sponsored coverage, drug pricing, PBMs and the administrative burdens impacting the system. Saum's insights help connect healthcare spending to broader economic issues while exploring potential reforms and the role of technology in improving efficiency. Saum highlights how choice and innovation distinguish the U.S. healthcare system, explores the reasons behind exorbitant drug prices, and examines the potential solutions, challenges, and trade-offs involved in lowering costs while striving to improve access, quality, and affordability. The opinions expressed by Saum in this episode are his own and do not represent the views of his employer. We discuss: The US healthcare system: financial scale, integration with economy, and unique challenges [5:00]; Overview of how the US healthcare system currently works and how we got here [9:45]; The huge growth and price impact due to the transition from out-of-pocket payments in the 1950s to the modern, third-party payer model [18:30]; The unique structure and challenges of the US healthcare system compared to other developed nations [22:00]; Overview of Medicare and Medicaid: who they cover, purpose, and impact on healthcare spending [27:45]; Why the US kept a employer-sponsored insurance system rather than pursue universal healthcare [32:00]; The evolution of healthcare insurance: from catastrophic coverage to chronic disease management [36:00]; The challenge of managing healthcare costs while expanding access and meeting increased demand for chronic illness care [44:15]; Balancing cost, choice, and access: how the US healthcare system compares to Canada [48:45]; The role of the US in pharmaceutical innovation, it's impact on drug pricing, and the potential effects of price controls on innovation and healthcare costs [56:15]; How misaligned incentives have driven up drug prices in the US [1:05:00]; The cost of innovation and choice, and the sustainability of the current healthcare cost expenditures in the US in the face of a shrinking workforce and aging population [1:11:30]; Health outcomes: why life expectancy is lower in the US despite excelling at extending lifespan beyond 70 [1:18:45]; Potential solutions and challenges to controlling drugs costs in the US while balancing choice and access and preserving innovation [1:26:15]; Balancing GLP-1 drug innovation with affordability and healthcare spending sustainability [1:40:00]; Reducing healthcare spending: complexities, trade offs, and implications of making needed cuts to healthcare expenditures [1:46:45]; The role of government regulation, opportunities for cost savings, and more [1:56:15]; Hospital billing: costs, charges, complexities, and paths to simplification [2:01:15]; How prioritizing access and choice increased expenditures: reviewing the impact of healthcare exchanges and the Affordable Care Act [2:08:00]; Feasibility of a universal Medicare program, and what a real path to sustainable healthcare looks like [2:15:45]; The challenge of long-term care and the potential of innovation, like device-based therapies and AI, to improve health [2:23:15]; and More. Connect With Peter on Twitter, Instagram, Facebook and YouTube