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Discover why hormones are off and what's really driving the imbalance. In this episode, we break down five root causes — from gut dysfunction and disrupted sleep to chronic stress, appetite dysregulation, and omega-3 deficiency — and walk through what you can actually do to fix it. FEATURED PRODUCT Berberine is a powerful botanical compound that acts as a natural GLP-1 supporter — the same metabolic pathway targeted by medications like Ozempic — helping regulate blood sugar, reduce insulin resistance, and restore appetite signaling from the gut. Since metabolic hormones like insulin and leptin are the first to derail your entire hormone cascade, Berberine directly addresses one of the deepest root causes discussed in this episode. It also supports gut microbiome diversity, making it a foundational tool for anyone working to reclaim hormonal balance naturally.
Bài của Chị Julianne Holt-Lunstad, Giáo Sư Tâm Lý Học trường Brigham Young University, Utah, Hoa Kỳ Tất cả chúng ta có thể sẽ có những lúc cảm thấy cô đơn. Đôi khi cảm giác cô đơn có thể thực sự lành mạnh và hữu ích, khi nó là một tín hiệu sinh học cho […] The post Podcast số 575 – Liahona tháng 9, 2024 – Không Còn Cô Đơn Nữa: 7 Cách để Kết Nối – Julianne Holt-Lunstad appeared first on Thánh Hữu Việt Nam.
She had a baby. Then her cycle disappeared — and nobody told her what that actually meant, or when it might come back, or whether she could get pregnant again before it did. Rose McKenzie has spent over a decade helping women understand their hormones in the moments when they feel most invisible: irregular cycles, postpartum, perimenopause. And she'll tell you plainly — the postpartum body is not a mystery. It's a system coming back online. The problem is nobody's watching the data.Rose is the clinical manager at Mira and a natural family planning practitioner with more than 10 years of experience helping women use hormone tracking not just for fertility, but for whole-body health awareness. Today she joins Dr. Susan Fox for a conversation about what's actually happening to your hormones after birth — and why tracking them postpartum is one of the most informed things a new mother can do, whether she wants to conceive again, avoid conceiving, or simply understand her own body.You'll learn why your hormones don't flip back on like a light switch after birth — and what the slow train analogy actually tells us about your return to cycling, why ovulation can return as early as eight weeks postpartum even while breastfeeding — and why that matters more than whether your period has come back, what the Lactational Amenorrhea Method (LAM) actually requires — and why almost everyone gets "kicked out" of it sooner than they expect, why a positive LH surge is not confirmation of ovulation — and what progesterone has to do with it, what "cycle wonky" means and why your first one to four cycles back are not your baseline, what the teeter-totter between prolactin and the body's drive to ovulate looks like on a hormone chart, how intentionally disrupting your nursing pattern — carefully and with support — can help jump-start ovulation for those trying to conceive while still breastfeeding, why tracking postpartum hormones led to two PCOS diagnoses that conventional medicine would have missed entirely, what Mira actually measures and why an LH strip alone doesn't give you the full picture, and why Mira is data — not a diagnosis, not a treatment plan, and not a standalone method for avoiding pregnancy. This episode is for you if you've just had a baby and have no idea when your hormones will return or what "normal" even looks like right now, you're breastfeeding and want to understand whether pregnancy is actually possible for you right now, you want to conceive again and aren't sure if your body is hormonally ready, you've been assuming your period has to come back before ovulation does, you're curious about natural family planning and want to understand how hormone tracking fits into it, or you want to stop floating around postpartum and start actually knowing what your body is doing. Support your fertility journey with Preconception Plan at Health Youniversity. Learn more here: https://healthyouniversity.co/programs
VOV1 - Chiều nay (22/5), UBND tỉnh Quảng Trị và Tổng Công ty Đường sắt Việt Nam tổ chức hội nghị ký kết biên bản ghi nhớ hợp tác giai đoạn 2026 – 2030, thống nhất và thực hiện các hoạt động quảng bá, xúc tiến du lịch.Tham dự lễ ký kết, về phía lãnh đạo tỉnh Quảng Trị có ông Lê Hồng Vinh, Phó Bí thư Tỉnh ủy, Chủ tịch UBND tỉnh cùng lãnh đạo các sở, ngành, đơn vị, địa phương của tỉnh Quảng Trị.Về phía lãnh đạo Tổng Công ty Đường sắt Việt Nam có ông Đặng Sỹ Mạnh, Chủ tịch Hội đồng thành viên Tổng Công ty Đường sắt Việt Nam.Lãnh đạo bộ, ngành, cơ quan báo chí Trung ương và lãnh đạo tỉnh Quảng Trị chứng kiến lễ ký biên bản hợp tác
Low testosterone isn't just a “male aging” issue — and your thyroid may be playing a much bigger role than you realize. In this episode of Your Thyroid Health, we explore the surprising connection between hypothyroidism and testosterone levels in both men and women.Learn how low thyroid hormone can disrupt key hormones like testosterone, LH, FSH, and SHBG, leading to symptoms like fatigue, weight gain, low libido, depression, brain fog, muscle loss, and sexual dysfunction. We also break down why many symptoms of low testosterone overlap with hypothyroidism — and why so many people are misdiagnosed or overlooked.You'll discover:How hypothyroidism affects testosterone productionWhy thyroid dysfunction can disrupt hormone balanceThe warning signs of low testosteroneWhether treating hypothyroidism can restore testosterone naturallyWhen testosterone replacement therapy may — or may not — help
[깊이 있는 경제뉴스] 1) 땅 부족한 서울.. LH연구원 “한강 위에 집 짓자” 2) 주식 거래 폭증에.. 초과 세수 수혜 받는 농어촌 - 김치형 경제뉴스 큐레이터 - 라예진 이코노미스트 기자 [친절한 경제] 금리가 오르면 왜 주가 하락을 걱정하나요 - 청취자 김다미 씨
VOV1 - Một trung tâm thí điểm quốc gia về ứng dụng robot thông minh đã khánh thành hôm 16/5 tại Hàng Châu, thủ phủ tỉnh Chiết Giang, miền Đông Trung Quốc.Trung tâm thí điểm quốc gia về ứng dụng trí tuệ nhân tạo (AI) này hiện đào tạo hơn 130 robot hoạt động trong hơn 30 kịch bản nghề, từ phục vụ ăn uống, bán lẻ không người, biểu diễn sự kiện đến kiểm tra đường dây điện, thu lượm trái cây và vận hành giếng khoan. Đây hiện là cơ sở thí điểm quốc gia duy nhất về ứng dụng AI cho robot thông minh tại Trung Quốc.Ông Hoàng Địch, trưởng nhóm Đổi mới hiệp đồng trí tuệ hiện thân tại Công ty Cung cấp điện Hàng Châu thuộc Tập đoàn Lưới điện Quốc gia Trung Quốc, cho biết:“Nhiều robot có thể hoạt động rất tốt trong phòng thí nghiệm, nhưng khi đưa ra thực địa, chúng lại mất phương hướng. Để giải quyết các khó khăn của robot thông minh trong ứng dụng thực tế, chúng tôi theo dõi lực tác dụng và sự thay đổi trọng tâm của robot theo thời gian thực, buộc nó phải học cách chủ động điều hướng. Chúng tôi huấn luyện robot hiểu thiết bị bằng cách sử dụng dữ liệu video tại chỗ, hiệu chỉnh lực thao tác và độ chính xác bằng cách thu thập dữ liệu từ các khớp và động cơ”.Công nghệ robot và chuỗi công nghiệp trí tuệ hiện thân ở Trung Quốc hiện vẫn còn khá phân mảnh trong các lĩnh vực như sức mạnh tính toán, dữ liệu, mô hình và kịch bản. Cách doanh nghiệp làm việc đơn lẻ. Nhiều đổi mới về trí tuệ hiện thân vẫn đang trong giai đoạn nghiên cứu và phát triển, thiếu môi trường thử nghiệm quy mô lớn, gây khó khăn cho việc biến nguyên mẫu thành sản phẩm. Việc thành lập cơ sở này có thể thúc đẩy sự hợp tác và phối hợp trong lĩnh vực AI.Ông Lý Hưng Đằng, Phó Tổng giám đốc Công ty TNHH Công nghệ Trung tâm Thí điểm AI Hàng Châu, nhấn mạnh trung tâm này nhằm mục đích phát triển một nền tảng thúc đẩy sự hợp tác sâu rộng với các công ty robot trên cả nước, cũng như các doanh nghiệp thượng nguồn và hạ nguồn trong chuỗi công nghiệp, để chuyển đổi lợi thế riêng thành sức mạnh tổng hợp.Sự phát triển của robot hình người đại diện cho một bước chuyển mình quan trọng của AI từ thế giới ảo sang các ứng dụng thực tế. Ở Trung Quốc, công nghệ này đang nhanh chóng chuyển từ phòng thí nghiệm sang các sản phẩm công nghiệp và đã được xác định là một ngành công nghiệp tương lai đòi hỏi tầm nhìn chiến lược trong Quy hoạch 5 năm lần thứ 15 (2026-2030) của nước này.Theo các chuyên gia, việc kết hợp giữa những đột phá công nghệ liên tục và sự hoàn thiện không ngừng của hệ sinh thái công nghiệp sẽ mở ra nhiều tiềm năng đổi mới hơn cho lĩnh vực trí tuệ hiện thân và robot./.Bích Thuận/VOV-Bắc KinhCác robot làm việc trên mô hình thu nhỏ tỷ lệ 1:1 của dây chuyền sản xuất máy tính cá nhân tại Trung tâm thí điểm ứng dụng AI quốc gia ở Hàng Châu. Ảnh: Tân Hoa xã.
The Waiting Well - Infertility, Faith-based Encouragement, Trying to Conceive, Fertility
Try Inito — the fertility tool I've personally started using as Josh and I prepare to TTC baby #3 after navigating both infertility and now secondary infertility.
Kapelu Slza proslavily písně jako Lhůta záruční či Holomráz. Na české hudební scéně září už 12 let. Její frontman Petr Lexa ale původně inklinoval k herectví.
Kapelu Slza proslavily písně jako Lhůta záruční či Holomráz. Na české hudební scéně září už 12 let. Její frontman Petr Lexa ale původně inklinoval k herectví.
Kapelu Slza proslavily písně jako Lhůta záruční či Holomráz. Na české hudební scéně září už 12 let. Její frontman Petr Lexa ale původně inklinoval k herectví.
Kapelu Slza proslavily písně jako Lhůta záruční či Holomráz. Na české hudební scéně září už 12 let. Její frontman Petr Lexa ale původně inklinoval k herectví.
Kapelu Slza proslavily písně jako Lhůta záruční či Holomráz. Na české hudební scéně září už 12 let. Její frontman Petr Lexa ale původně inklinoval k herectví.
Kapelu Slza proslavily písně jako Lhůta záruční či Holomráz. Na české hudební scéně září už 12 let. Její frontman Petr Lexa ale původně inklinoval k herectví.
Kapelu Slza proslavily písně jako Lhůta záruční či Holomráz. Na české hudební scéně září už 12 let. Její frontman Petr Lexa ale původně inklinoval k herectví.
Kapelu Slza proslavily písně jako Lhůta záruční či Holomráz. Na české hudební scéně září už 12 let. Její frontman Petr Lexa ale původně inklinoval k herectví.
"Tout est normal." Combien de fois t'es-tu fait dire ça en tenant une feuille de résultats dans les mains, pendant que ton corps criait le contraire?Le problème, ce n'est pas toi. C'est quoi on mesure — et comment on interprète.Dans cet épisode, on parle du bilan annuel complet que toute femme devrait faire. Pas le bilan standard. Le vrai. Celui qui donne des réponses.On couvre : — Pourquoi "être dans les normes" ne veut pas dire "être en santé" (et c'est quoi la courbe de Gauss) — Les hormones sexuelles : estrogènes, progestérone, testostérone, DHEA, FSH, LH, prolactine — et pourquoi chacune compte — Le cortisol et les surrénales : l'hormone qu'on oublie presque toujours — La thyroïde complète : TSH, T3, T4, T3 inverse, anticorps — C'est de la science vulgarisée. C'est pratique. Et c'est exactement ce dont vous avez besoin pour arrêter de chercher des réponses sans jamais en trouver.On se fait la PART 2 semaine prochaine ! Alie xx Hébergé par Ausha. Visitez ausha.co/politique-de-confidentialite pour plus d'informations.
Kapelu Slza proslavily písně jako Lhůta záruční či Holomráz. Na české hudební scéně září už 12 let. Její frontman Petr Lexa ale původně inklinoval k herectví.
No episódio de hoje do Radar Médico, Juliane B. Braziliano, endocrinologista, apresenta os principais pontos do novo posicionamento brasileiro sobre o cuidado de pacientes com hipogonadismo masculino, publicado em conjunto pela SBEM, SBU e ABEMSS.O documento reforça que o diagnóstico do hipogonadismo deve combinar sinais e sintomas clínicos compatíveis com confirmação laboratorial inequívoca de deficiência de testosterona, além de destacar critérios diagnósticos padronizados, investigação etiológica e orientações atualizadas para terapia de reposição hormonal.Tópicos abordados:• Quando investigar deficiência de testosterona• Critérios laboratoriais e interpretação da testosterona total e livre• Diferença entre hipogonadismo primário, secundário e funcional• Papel do LH, FSH, SHBG e exames complementares• Indicações e contraindicações da terapia de reposição hormonal (TRT)• Formulações recomendadas e monitoramento clínico• Obesidade, MOSH e importância das mudanças de estilo de vida
This episode is a special one. Sara Jensen, co-founder and Co-CEO of Hugh & Grace invited me to join her for a live conversation in honor of National Infertility Awareness Week and the interview was so good, I knew I had to share it with all of you here on the Egg Whisperer Show. Sara has walked the deeply personal road of unexplained infertility for 14 years, ultimately building her family through the incredible gift of surrogacy. And, she and her husband Ben and channeled that journey (and what they learned) into a company dedicated to hormone-supportive, toxin-free wellness products. Together, Sara and I unpack some of the fertility trends we both are seeing in 2026. From understanding your fertility before you're trying to conceive, to the emotional marathon of IVF, to the role environmental toxins play in hormone health, and the topic of sperm maxing and egg maxing - we tackle many of the trending topics. And, we share what it really takes to prepare your body, protect your partnership, and make empowered choices on the path to parenthood. In this episode, we cover these fertility trends from 2026: Trimester Zero: what it means to truly prepare for pregnancy, why it matters for both partners, and how men can improve sperm quality through behavioral changes The TUSHY Method: my method for getting the foundational fertility workup done (tubes, uterus, sperm, hormones, and genetics) before surprises arise Egg maxing & sperm maxing: the supplements I actually recommend (CoQ10, NAD+), what to skip, and why "more is not better" when it comes to your supplement stack At-home fertility testing tools: how to use LH tests, the Proof Complete kit, and ovulation apps like Oura accurately, and the timing mistakes that cause couples to miss their window The emotional toll of fertility treatments: how to build your fertility support team early, manage IVF-related stress, and protect your relationship throughout the process Environmental toxins and hormone health: how everyday skincare and household products can impact your hormones, and what Sara learned firsthand after 6 rounds of IVF The fertility trends no one is talking about: why biology hasn't changed even as more women over 40 are having babies, and what declining birth rates mean for all of us Resources: Hugh & Grace (hormone-supportive, toxin-free wellness products) The Egg Whisperer Show (Dr. Aimee's podcast) on Spotify Yo Sperm Test (at-home semen analysis) Fellow sperm testing kit Legacy male fertility testing Proof Complete fertility hormone test The Hermosa Study (research on chemical exposure and teens): https://cerch.berkeley.edu/research-programs/hermosa-study Oura Ring (fertility & cycle tracking): ouraring.com
Era actualitat dera Val d'Aran en aran
We are long overdue for an updated conversation on low estrogen — and today I'm pulling it all apart. Estrogen has been villainized for far too long, and I want to change that. This isn't just about reproductive health or getting your period. Estrogen is a master communicator that touches your brain, heart, bones, gut, skin, mood, sleep, libido, and so much more. In this episode, I cover: Why low estrogen is one of the most missed and underdiagnosed issues for women between 35 and 65 The three types of estrogen (E1, E2, E3) and why estradiol matters so much beyond fertility Why estrogen often increases first in perimenopause before it eventually declines — and what that means for your symptoms The symptom clusters to pay attention to, organized by body system: Brain, mood & sleep — brain fog, anxiety, emotional flatness, rage responses, waking between 2–4am Body composition & metabolic health — belly fat shifts, muscle loss, fatigue, insulin resistance Skin, hair & connective tissue — collagen loss, hair texture changes, joint pain, frozen shoulder, ACL issues Vaginal & urinary health (GSM) — dryness, painful sex, recurring UTIs, urgency, bladder changes Cardiovascular & bone health — rising LDL, heart palpitations, hot flashes, bone density loss Gut & digestion — bloating, constipation, new food sensitivities, the estrobolome and estrogen recirculation The symptoms I personally would never ignore (waking 2–4am, joint pain without a clear cause, rapid body composition shifts, recurrent UTIs, brain fog affecting your work, heart palpitations) What to ask your doctor to test: FSH, LH, estradiol, progesterone, testosterone, full thyroid panel, fasting glucose and insulin, cholesterol, CBC, SHBG — and when functional testing like DUTCH or HTMA may be useful My thoughts on DIM, sulforaphane, calcium-d-glucarate, magnesium, adaptogens (ashwagandha, rhodiola, maca), omega-3s, creatine, collagen, and vitamin D Nutrition strategies — phytoestrogen-rich foods, cruciferous veggies, fiber, protein targets (30–40g per meal), healthy fats, and what to cut Movement priorities — why resistance training 3–4x/week is non-negotiable for bone, muscle, and metabolic health Hormone replacement therapy — what options exist, how to approach the conversation with your provider, and why your protocol will evolve over time Let's dive in! Thank you for joining us today. If you could rate, review & subscribe, it would mean the world to me! While you're at it, take a screenshot and tag me @jennpike to share on Instagram – I'll re-share that baby out to the community & once a month I'll be doing a draw from those re-shares and send the winner something special! Click here to listen: Apple Podcasts – CLICK HERESpotify – CLICK HERE This episode is sponsored by: withinUs | Use the code JENNPIKE20 at withinus.ca for a limited time to save 20% off your first order and 20% off your first subscription order St. Francis | Go to stfrancisherbfarm.com and save 15% off your all your orders with code JENNPIKE15 Eversio Wellness | Go to eversiowellness.com/discount/jennpike15 and save 15% off every order with code JENNPIKE15 /// not available for "subscribe & save" option Free Resources: Free Perimenopause Support Guide | jennpike.com/perimenopausesupport Free Blood Work Guide | jennpike.com/bloodworkguide The Simplicity Sessions Podcast | jennpike.com/podcast Get 20% on thewalkingpad.com using code "JENNPIKE20" Metabolic Guide | jennpike.com/metabolic-guide Get discounts at happybumco.com using code "JENNPIKE" *code doesn't apply with Black Friday sale* Programs: Ignite: Your 8-Week Body Transformation Program | https://jennpike.com/ignite The Peri & Menopause Project - Join the Waitlist | jennpike.com/theperimenopauseproject Synced Virtual Fitness Studio | jennpike.com/synced Services: Work With Jenn | https://jennpike.com/work-with-jenn/ Functional Testing | jennpike.com/testing-packages Business Mentorship | The Audacious Woman Mentorship: jennpike.com/theaudaciouswoman Connect with Jenn: Instagram | @jennpike Facebook | @thesimplicityproject YouTube | Simplicity TV Website | The Simplicity Project Inc. Have a question? Send it over to hello@jennpike.com and I'll do my best to share helpful insights, thoughts and advice.
VOV1 - Ngày 25/4, không khí Giỗ Tổ Hùng Vương lan tỏa tại nhiều điểm vui chơi ở TP.HCM, với chuỗi hoạt động văn hóa, tâm linh và giải trí phong phú. Từ nghi lễ dâng hương, rước lễ đến các chương trình nghệ thuật, tất cả góp phần kết nối cộng đồng, tôn vinh giá trị truyền thống. Dịp lễ này, tại Khu Du lịch Văn hóa Suối Tiên diễn ra Đại lễ Giỗ Tổ Hùng Vương với chuỗi hoạt động mang đậm dấu ấn văn hóa - tâm linh, thể hiện lòng thành kính tri ân công đức tổ tiên. Trong đó, lễ cúng tế và dâng hương các vị vua Hùng thể hiện đạo lý “Uống nước nhớ nguồn” của người Việt Nam, với ý nghĩa kết nối hàng ngàn trái tim của những người con phương Nam hướng về đất Tổ.Lễ rước sắc thần trong Lễ Kỳ Yên đình làng Nam Bộ (Ảnh: Lệ Hằng)
Here is LH's Final Mock Draft for 2026!! Complete with odds on every single pick that is sure to hit!! Listen to win thousands of dollars!! Thanks for tuning in!!Sponsored by www.texastelehealth.com
Here is LH's Final Mock Draft for 2026!! Complete with odds on every single pick that is sure to hit!! Listen to win thousands of dollars!! Thanks for tuning in!! Sponsored by www.texastelehealth.com
Did you know that when that little test strip gives 2 lines and says ovulation has occurred.... that's not exactly what it's telling you? LH surge doesn't equal ovulation and this episode gets into that and so much more! Timing your babydancing just right, what position to do it in and so many other listener questions are addressed in today's episode. As promised, Podcast Host Heather has provided her link to join her email subscriber list and grab her top tip to conceive now! Click here: Grab my tip! TRIGGER WARNING: This show may discuss sensitive topics that are difficult for some listeners to hear. Use your own discretion. Reminder: This podcast is not intended to treat, or advise, your medical journey in anyway. Always discuss all things medical with your own medical team. Heather is a Doctor, but she's not yours. Nothing in this podcast episode constitutes health, or medical (physical or mental) advice. This podcast is for informational and educational purposes only. See full website disclaimer at https://canyoucurecancer.com/disclaimer If you'd love to hear your company's advertisement read on this podcast by Heather for Season 4, or you'd like to hear your own pre-recorded ad run during the show, email Heather to see if Sponsor space is still available. If you have topics you want covered on this podcast, email Heather at the email below. Heather's email is heather@canyoucurecancer.com Thank you for all of the listens, shares, follows and downloads! If you haven't yet, don't forget to subscribe, so you never miss an episode! Letting just one friend know about an episode that inspired you will help me immensely, while passing on the inspiration to someone you love! My listeners are the absolute best, thank you for always supporting me. Keep returning and remember to subscribe in case additional weekly episodes are added, so that you never miss a show!
VOV1 - Bệnh viện Bạch Mai sẽ giúp đỡ, hỗ trợ chuyên môn để Bệnh viện đa khoa tỉnh Sơn La trở thành cơ sở y tế tuyến tuyến cuối của khu vực Tây Bắc, đầu tư khoảng 2000 tỷ đồng để mở rộng quy mô từ 500 giường lên 1000 giường.Đó là thông tin được đề cập tại Hội nghị “Tăng cường năng lực y tế tỉnh Sơn La và ký thỏa thuận hợp tác toàn diện về y tế giai đoạn 2026-2031” do Ủy ban nhân dân tỉnh Sơn La phối hợp với Bệnh viện Bạch Mai tổ chức ngày 18/04 tại Tòa nhà Hành chính của Ủy ban nhân dân tỉnh Sơn La. Hội nghị “Tăng cường năng lực y tế tỉnh Sơn La và ký thỏa thuận hợp tác toàn diện về y tế giai đoạn 2026-2031”- Ảnh Lê Hồng
This week LH improves the Browns and sends the Bears to the Super Bowl!!! Thanks for tuning in!!!Sponsored by www.texastelehealth.com
This week LH improves the Browns and sends the Bears to the Super Bowl!!! Thanks for tuning in!!! Sponsored by www.texastelehealth.com
Era actualitat dera Val d'Aran en aran
Send us Fan MailWhat if your timing was perfect every month — great cervical mucus, a clear LH surge, a healthy luteal phase — and still no positive test? For some women, the missing piece is not ovulation at all. It is the uterine lining that receives the embryo, and whether that environment is truly ready to support implantation.In this episode of Cycle Wisdom, Dr. Monica Minjeur unpacks endometrial receptivity — what a thin uterine lining actually means, how estrogen and progesterone work together to prepare it, and the stepwise, cycle-timed plan to improve thickness, blood flow, and function without jumping straight to procedures. Through the story of Aubrey, a 33-year-old who had been told she might need IVF after a thin lining was found on ultrasound, you will see how targeted evaluation and a few key changes transformed her results within three cycles.You will learn:What endometrial thickness numbers actually mean and what to look for on ultrasoundWhich underlying causes — insulin resistance, low iron, poor estradiol response — quietly thin the liningHow to improve uterine lining through cycle-timed lifestyle, nutrient, and hormone supportIf implantation has felt like the missing piece in your fertility journey, there may be more answers available than you have been given. Learn more or schedule a free discovery call at radiantclinic.com.
Era actualitat dera Val d'Aran en aran
This week FGH is back and LH improves the Raiders to 6 wins for next season and sends the Cowboys to the Super Bowl!!! Thanks for tuning in!! Sponsored by www.texastelehealth.com
This week FGH is back and LH improves the Raiders to 6 wins for next season and sends the Cowboys to the Super Bowl!!! Thanks for tuning in!! Sponsored by www.texastelehealth.com
FGH is back again and LH has taken on the challenge of fixing his beloved NY Jets and sending the LA Rams to the Super Bowl with this years draft!! Thanks for tuning in!!Sponsored by www.texastelehealth.com
FGH is back again and LH has taken on the challenge of fixing his beloved NY Jets and sending the LA Rams to the Super Bowl with this years draft!! Thanks for tuning in!! Sponsored by www.texastelehealth.com
durée : 00:36:54 - Le téléphone sonne - par : Fabienne Sintes - L'époque adore les désaccords, mais supporte de moins en moins la contradiction. Dans le couple, en famille, entre amis ou sur les grands sujets de société, la dispute semble partout. Alors, comment se disputer sans basculer dans le conflit ? - réalisation : Thomas Lenglain, Pierre Dessertenne, Amaury Bocher, Mathias Dubois, Philippe Lefébure - invités : Michel Eltchaninoff Rédacteur en chef de Philosophie Magazine, agrégé et docteur en philosophie, il est spécialisé en phénoménologie et en philosophie russe., Héloïse Lhérété Directrice de la rédaction du magazine Sciences Humaines Vous aimez ce podcast ? Pour écouter tous les épisodes sans limite, rendez-vous sur Radio France
We unpack the blunt claim “if you're not horny, you're not healthy” and turn it into a practical conversation about hormones, lifestyle, and what libido can and cannot tell you about your health. We share real-world examples from training, sleep, stress, alcohol, nutrition, and medications to help you spot red flags and make smart changes without panic. • libido as a subjective signal rather than a diagnostic test • why sex drive changes with age and what “normal” depends on • a simple breakdown of the HPG axis plus LH and FSH • processed food, excess body fat, and testosterone to estrogen conversion • why modern testosterone may be declining across decades • microplastics and endocrine disruptors plus big-rock mitigation steps • sleep quality, cortisol, and why chronic stress crushes recovery • alcohol, testosterone, and the reality behind “whiskey dick” • metabolic syndrome markers and why bloodwork matters • overtraining versus underrecovery and using libido as a personal cue • how aerobic volume and low calories can backfire even on HRT • blood pressure meds, low blood pressure, and a candid ED story • cheat meals as a weekly math problem and defining what “cheat” means • worst fitness advice we keep hearing and why it fails • the one exercise we'd keep forever and the bodyweight backup pick I'll be putting out IG things for you guys to ask questions, submit whatever questions.Follow us on Instagram here! https://www.instagram.com/doubleedgefitness/
In this episode, Scott Sheaffer explores the groundbreaking and often controversial topic of canine hormone replacement therapy (HRT) for neutered male dogs. For years, "fixing" our dogs was seen as the gold standard of care, but we are now discovering the long-term behavioral and physical costs of "hormonal bankruptcy." From irrational fears and noise phobias to muscle wasting and joint issues, the lack of testosterone in neutered males might be a hidden culprit behind many common behavioral struggles in some dogs.Learn about the science of "Spay-Neuter Syndrome" and how the Dogosterone™ protocol is helping thousands of dogs regain their confidence and mobility. Scott discusses the role of luteinizing hormone (LH) in anxiety, the physical-behavioral connection, and why your dog's "training issue" might actually be a metabolic one. Whether your dog is a senior slowing down or a young rescue struggling with reactivity, this episode provides new insights into your dog's behavior.You can visit USADogBehavior.com for lots of dog behavior resources—almost all of them are free—including videos, blog articles, and past podcast episodes to help you understand your dog.Scott Sheaffer provides customized behavioral seminars for shelters, rescues, and veterinary teams—available online or on-site—focused on real-world strategies, with discounted or complimentary options available. Learn more about Scott Sheaffer's behavioral seminars.Find us at USADogBehavior.com.Follow us on Facebook.DisclaimerThis podcast is for educational purposes only and is not a substitute for professional advice. If your dog is displaying aggression toward humans, consult an experienced and knowledgeable canine behavior professional who uses humane, non-aversive methods, and always take precautions to keep others safe.Scott Sheaffer and USA Dog Behavior, LLC, are not responsible for any outcomes resulting from the use or interpretation of the information shared in this podcast.
Send us Fan MailIn this episode, our stack of books is tied together with the common theme of being our favorite reads of 2026 to date. Our 5 Star So Far! And, we each have 5 books so, 5 is our lucky number today. Featured Books:The Sunflower Boys by Sam Wachman (LH)Trial of the Sun Queen by Nisha J Tuli (LH)Thistlemarsh by Moorea Corrigan (LH)I, Medusa by Ayana Gray (LH)Lady Tremaine by Rachel Hochhauser (LH and LP)The Winter of the Dollhouse by Laura Amy Schlitz (LP)One Big Open Sky by Lesa Cline-Ransome (LP)This Here is Love by Princess Joy L. Perry (LP)Can't We Talk About Something More Pleasant by Roz Chast (LP)Our Darkest Night by Jennifer Robson (LP)Books Mentioned in This Episode:Stone Blind by Natalie Haynes Medusa's Sisters by Lauren J.A. BearRule of Aurora King by Nisha J TuliAdditional Books That Go Along with Our Stack:Love By the Book by Jessica George Skylark by Paula McLain Ways to contact us:Join us on Patreon for extra content: https://www.patreon.com/c/BookBumblePodcastFollow us on Instagram - @thebookbumbleFacebook: Book BumbleOur website: https://thebookbumble.buzzsprout.comEmail: bookbumblepodcast@gmail.comSupport the showPlease rate and review us, subscribe, follow us on Insta, and join our Team Patreon! It won't be the same without you!
This week LH breaks down how to fix the Redskins and send the Bills to the Super Bowl through the 2026 Draft!!! This is Episode 1 of our build up to the 2026 NFL Draft....we look forward to seeing you all in Pittsburgh!! Thanks for tuning in!!Sponsored by www.texastelehealth.com
This week LH breaks down how to fix the Redskins and send the Bills to the Super Bowl through the 2026 Draft!!! This is Episode 1 of our build up to the 2026 NFL Draft....we look forward to seeing you all in Pittsburgh!! Thanks for tuning in!! Sponsored by www.texastelehealth.com
Liver Boost from MSW Nutrition is designed to support phase 1 and phase 2 detoxification pathways — the exact processes your liver uses to metabolize and clear estrogen. During perimenopause, when hormone levels fluctuate and detox pathways can become sluggish, supporting liver function is foundational. Liver Boost helps your body process hormones more efficiently, which can ease bloating, mood swings, skin changes, and stubborn weight fluctuations discussed throughout this episode.
Dr. Natalie Crawford, board-certified OB-GYN and REI, answers your fertility questions. I'm almost 35 and currently going through IVF. I have PCOS and insulin resistance and have had four early miscarriages despite normal testing and blood work. I've also had two laparoscopic surgeries for cysts, one showing mild endometriosis, and a uterine biopsy that showed no inflammation. Given this history, how successful might IVF be for us? What transfer protocol do you recommend after Lupron and letrozole suppression for positive ReceptivaDX results—modified natural or medicated—and what factors guide that decision? Can autoimmune conditions contribute to secondary infertility? I have a four-year-old but have since experienced five miscarriages and have diminished ovarian reserve. After four cycles I've only had one embryo tested and it was aneuploid, and my doctor says autoimmune testing may be the next step if endometriosis testing is negative. In a 28-day cycle, is it concerning if a positive LH surge happens around days 15–16? And when tracking cycles, do you count day one as the first day you see bleeding even if it starts midday, or the following day? I'm 35 and planning for pregnancy. What are the most important first steps I should take now to set myself up for success? Pre-order Dr. Crawford's debut book, The Fertility Formula, now! https://www.nataliecrawfordmd.com/book Want your questions answered on the next episode? Ask them here! https://www.nataliecrawfordmd.com/qa-submissions Learn more about your ad choices. Visit megaphone.fm/adchoices
Testosterone levels in 40-year-old men are 30 percent lower than their fathers, and most doctors still have no idea what to do about it. -Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Dr. Justin Houman, a nationally recognized urologist and Assistant Professor of Urology at Cedars-Sinai Medical Center. Fellowship-trained and specializing in men's health, male fertility, and sexual medicine, Dr. Houman combines cutting-edge medical advancements with holistic lifestyle strategies to help men optimize testosterone, sexual health, and reproductive performance at every age. Together, Dave and Dr. Houman tear through the myths, the bad science, and the outdated medical dogma around testosterone, erectile function, fertility, and male sexual health. They cover everything from why testosterone levels have collapsed in a single generation, to the real story behind the FDA black box warning, to practical protocols for men who want to optimize without sacrificing fertility. This is the masterclass on men's health that no one else is having on record. This is essential listening for anyone serious about biohacking, longevity, human performance, hormone optimization, brain optimization, anti-aging, functional medicine, mitochondria, and Smarter Not Harder approaches to male health. You'll Learn: Why testosterone levels in 40-year-old men are 30 percent lower than their fathers and what is driving the collapse How low testosterone connects to anxiety, depression, high cholesterol, blood sugar dysregulation, and all-cause mortality risk The truth about the original testosterone and heart attack study and why it still has not been retracted How to preserve fertility while on TRT using Clomid, enclomiphene, and HCG Why daily low-dose Cialis is one of the cheapest and most effective longevity drugs available What shockwave therapy, PRP, exosomes, and Botox injections actually do for erectile function How red light therapy at 660 and 850 nanometers supports testosterone production and nocturnal erections The supplement stack including ashwagandha, tongkat ali, fadogia agrestis, and creatine that supports healthy hormone levels Why porn-induced ED is epidemic in young men and how to reverse it How PT-141 and peptides fit into a complete male optimization protocol Thank you to our sponsors! Pre-order Arthur Brook's new book today at themeaningofyourlife.com. You can also see Arthur speak live at the 2026 Beyond Biohacking Conference fatty15 | Go to https://fatty15.com/dave and save an extra $15 when you subscribe with code DAVE.Establish a powerful foundation for sustained wellness with Pique. Unlock 20% off: piquelife.com/DAVE BrainTap | Go to http://braintap.com/dave to get $100 off the BrainTap Power Bundle. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: testosterone, low testosterone, TRT, testosterone replacement therapy, male fertility, erectile dysfunction, ED, men's health, sexual health, hormone optimization, Dave Asprey, biohacking, longevity, anti-aging, human performance, Dr. Justin Houman, Cedars-Sinai, urologist, shockwave therapy, PRP, exosomes, Botox penis, red light therapy, nitric oxide, Cialis, tadalafil, Viagra, sildenafil, PT-141, Melanotan, peptides, ashwagandha, tongkat ali, fadogia agrestis, creatine, Danger Coffee, Smarter Not Harder, Kyzatrex, clomid, enclomiphene, HCG, prolactin, cabergoline, porn-induced ED, refractory period, fertility, sperm health, spermatogenesis, FSH, LH, estrogen, aromatization, functional medicine, supplements, mitochondria, circadian rhythm, sleep optimization, cortisol, microplastics, inflammation, cardiovascular health, dementia, all-cause mortality, nocturnal erections, penile health, male optimization Resources: • Learn More About Dr. Houman's Work At: https://houmanmd.com/ • Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/ • Upgrade Labs: https://upgradelabs.com Timestamps: 00:00 – Introduction 01:15 – Low Testosterone Epidemic 04:23 – Ejaculation & Testosterone 07:30 – Refractory Period & Aging 09:58 – Porn-Induced ED 11:09 – Cabergoline & Prolactin Management 12:42 – Oral Testosterone 13:24 – Testosterone Target Levels 16:46 – Supplements for Testosterone 18:46 – Anxiety-Based ED 26:23 – Penis Enhancement Options 27:37 – Shockwave Therapy 28:57 – Cialis for Longevity 29:56 – Fat & Filler Injections 34:50 – Pre-Sex Optimization 40:13 – Red Light Therapy 42:18 – Heat & Cold for Testosterone 43:35 – Underwear & Microplastics 44:58 – Testosterone & Fertility 49:15 – HCG & Preserving Fertility 52:00 – Testosterone Dosing Timing 53:22 – Creatine & Mitochondrial Health 55:20 – Overtraining Effects 56:24 – Peptides (PT-141) 59:08 – Optimal Diet for Fertility See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
On today's episode of The Wholesome Fertility Podcast, I'm joined by Jay Campbell (@jaycampbell333), health optimization expert, author, and founder of BioLongevity Labs, to explore the powerful intersection of peptides, metabolic health, and fertility. Jay shares how therapeutic peptides like HCG, HMG, and GLP compounds can support male fertility, insulin resistance, and metabolic balance when used correctly. We discuss the rise of GLP-1 medications, why microdosing matters, and how inflammation and visceral fat are major contributors to declining fertility rates. Beyond the physical, we also dive into mindset, consciousness, and how belief systems impact healing and reproductive outcomes. This conversation bridges cutting-edge science with empowered awareness, and offers a new perspective on fertility optimization in the modern world. Key Takeaways: Therapeutic peptides such as HCG and HMG can help stimulate FSH and LH to support male fertility. Chronic inflammation and visceral fat are major drivers of insulin resistance and declining fertility. GLP-1 medications can be helpful tools when microdosed and combined with proper lifestyle habits. Insulin-controlled living and metabolic flexibility are foundational for hormonal balance. Sustainable fat loss requires resistance training, adequate protein intake, and hormonal optimization. Environmental toxins and endocrine disruptors contribute to the global fertility decline. Mindset and consciousness play a significant role in healing, longevity, and reproductive success. Guest Bio: Jay Campbell (@jaycampbell333) is a global authority in hormone optimization, peptides, and human longevity, a five-time international bestselling author, and the co-founder of BioLongevity Labs—often called "the Amazon for biohackers." For more than two decades, he has led the field of metabolic health and anti-aging science, helping millions enhance vitality, repair their biology, and take control of their health. Known for cutting through misinformation, Jay translates complex biomedical research into practical, real-world strategies with integrity and no-BS clarity, blending cutting-edge science with a consciousness-driven approach that elevates biology, mindset, identity, and purpose. He is also the author of the upcoming book Metabolic Awakening, which addresses the global misuse of GLP drugs and introduces the first responsible, science-aligned framework for microdosing GLP peptides to support long-term metabolic repair rather than temporary weight loss. Connect with Jay: Follow him on InstagramVisit his website Disclaimer: The information shared on this podcast is for educational and informational purposes only and is not intended as medical advice. Please consult with your healthcare provider before making any changes to your health or fertility care. Ready to discover what your body needs most on your fertility journey? Take the personalized quiz inside The Wholesome Fertility Journey and get tailored resources to meet you exactly where you are: https://www.michelleoravitz.com/the-wholesome-fertility-journey For more about my work and offerings, visit: www.michelleoravitz.com Curious about ancient wisdom for fertility? Grab my book The Way of Fertility: https://www.michelleoravitz.com/thewayoffertility Join the Wholesome Fertility Facebook Group for free resources & community support: https://www.facebook.com/groups/2149554308396504/ Connect with me on social: Instagram: @thewholesomelotusfertilityFacebook: The Wholesome Lotus
Amor Nas Redes é um quadro do canal Não Inviabilize. Aqui você ouve as suas histórias misturadas às minhas!Use a hashtag #Negativo e comente a história no nosso grupo do telegram: https://t.me/naoinviabilizePUBLICIDADE CLEARBLUECom o Clearblue Teste de Gravidez Digital, você tem mais de 99% de precisão¹ e também a informação de quantas semanas². Descubra seu ritmo com Clearblue.Aviso:¹Mais de 99% de precisão na detecção da gravidez a partir do dia esperado damenstruação. ²Semanas desde a concepção exibidas como 1-2, 2-3 ou 3+ [na tela]Declaração regulatória:Mais de 99% de precisão a partir do dia do início esperado da menstruação. Maisde 99% de precisão na detecção do aumento do LH.Sempre consulte seu médico e leia as instruções. Registro ANVISA No: 80686360214,80686360215, 80686360212, 80686360213 80686360275#Publicidade #ClearblueConfirma #ParceriaClearblueQUER OUVIR MAIS HISTÓRIAS? BAIXE NOSSO APLICATIVO EM SUA LOJA APPLE/GOOGLE, CONHEÇA NOSSOS QUADROS EXCLUSIVOS E RECEBA EPISÓDIOS INÉDITOS DE SEGUNDA A QUINTA-FEIRA: https://naoinviabilize.com.br/assineEnvie a sua história bem detalhada para naoinviabilize@gmail.com, seu anonimato será mantido, todos os nomes, profissões e locais são trocados para preservar a sua identidade.Site: https://naoinviabilize.com.brTranscrição dos episódios: https://naoinviabilize.com.br/episodiosYoutube: https://youtube.com/naoinviabilizeInstagram: https://www.instagram.com/naoinviabilizeTikTok: https://www.tiktok.com/@naoinviabilizeX: https://x.com/naoinviabilizeFacebook: https://facebook.com/naoinviabilizeEdição de áudios: Depois O Leo Corta MultimídiaVinhetas: Pipoca SoundVoz da vinheta: Priscila Armani
Dr. Deb Muth 0:00 Welcome back to Let’s Talk Wellness Now. I’m your host, Dr. Zab, and we are continuing our discussion this week on 0:08 peptides. And so, if you haven’t heard our first conversation about peptides, 0:13 please go back and look at that episode. We talk all about the manufacturing, the safety, the quality of peptides, and we 0:20 dove into GLP1s. And today we’re going to dive into peptides for sexual 0:26 wellness, immune function, growth hormone, and all the amazing fun things 0:32 we can do with peptides. So, as usual, grab your cup of coffee or tea, settle 0:37 in, and let’s talk wellness now. And we’re going to take a short pause from our sponsor. I know we’ve got to do 0:44 that, you guys. They’re who keep us on the air. So, I’m going to pause for just a minute and be right back after this 0:50 message from our sponsor. Ladies, it’s time to reignite your vitality. Primal 0:56 Queen supplements are clean, powerful formulas made for women like you who want balance, strength, and energy that 1:03 lasts. Get 25% off at primal queen.com. Serenity Health. That’s primalqueen.com. 1:10 Serenity Health. Because every queen deserves to feel in her prime. All 1:15 right, everybody. We are back. And are you ready? We are talking all things peptide and I am opening the show today 1:23 with sexual wellness. Yes, I’m going there, you guys. I am going there. You 1:29 know, this has really become a big issue for people um of all ages. It’s not just 1:3 4us older people. It’s younger people, too. And there’s a whole variety of reasons why we have sexual dysfunction. 1:42 And when we’re talking about sexual dysfunction, we’re not just talking about it doesn’t work, right? Or I can’t 1:48 reach orgasm. A lot of it is around desire and um the thought of it and 1:54 wanting to connect, wanting to be kinder to one another, wanting to be touching 2:00 one another. A lot of it resolves or revolves around that. And so there are some peptides that can help us and I’m 2:08 really excited to be able to talk about those today. So the first one is called PT-141. 2:14 This targets the brain not the periphery. Right? So for many women I 2:20 will always tell you sex starts between here. It is a brain thing for us. It is 2:26 not necessarily a physical thing. For guys that’s a little different. It’s very physical. For women it’s all in our 2:32 brain. So tip for you men that are listening. You have to prime your woman’s brain first if you want her to 2:38 have sex with you that night. You have to be nice to her. You have to bring her flowers. Do the dishes for her. Do 2:45 something kind. Bring her a cup of coffee or tea or a glass of wine. Take her to dinner. You have to woo her. And 2:51 I don’t care how long you’ve been married. That has to happen. And tip number two, don’t say anything stupid 2:57 that day. I’m just being honest. When you guys say things that make us upset, 3:03 that lingers with us for the rest of the day. And it’s it’s a turnoff for us. And 3:08 for a lot of women, we can’t get past that when it comes time to snuggle at night. And sex doesn’t always have to be 3:14 at night either. So, you can tell I really love talking about this conversation, but we’re going to get into the peptide part of it because this 3:21 is going to help people. So, um, PT-141 is marketed as I’m going to slaughter 3:28 this name, Vali, and it represents a fundamentally different approach to 3:34 sexual dysfunction than the PDE5s inhibitors like Slenden, Viagra, 3:40 Tedataphil, which is Seialis. And while the PDE5 inhibitors work specifically by 3:47 enhancing blood flow to the genital tissues, PT-141 works centrally in the brain by 3:54 modulating neural s neural circuits involved in the sexual desire and 4:00 arousal. Now PT-41 is a cyclic hpatipeptide. It’s seven amino acid 4:07 peptide arranged in a cyclic structure that acts as a melanoortin receptor 4:13 agonist and with particularly the infinity for MC3R and MC4R subtypes. 4:20 It’s actually a metabolite of the melanotan 2, a peptide originally 4:26 developed for tanning that was also found to enhance sexual desire in early 4:31 studies. Now the melanoortin system in the brain is involved in multiple functions including energy homeostasis 4:39 but it also is involved in sexual motivation and arousal behaviors. The FDA approved PT-141 in 2019 specifically 4:48 for the treatment of acquired generalized hypoactive sexual desire 4:54 HSDD in permenopausal women. So for the first time we have a medication that was 5:01 approved by the FDA to use for women for sexual dysfunction. We have had all of 5:07 these seialis tedataphil viagros for men but we had nothing for women. And so 5:12 this is amazing that this is available for women and approved by the FDA. It’s a big deal. This represents the first 5:19 and only FDA approved medication specifically targeting these circuits of sexual desire rather than the peripheral 5:27 arousal mechanisms. And this indication is quite specific, meaning it was developed at some point, not lifelong. 5:35 So I if you’ve had sexual dysfunction your entire life, this medication was 5:40 not approved for you. But if it’s something that you developed over time, like when you went through pmenopause or 5:46 menopause or some women have this experience happen after childirth, that’s what we’re talking about here. 5:53 Now, it’s also not just um supposed to be used if you dislike your partner, 5:59 right? If your relationship is bad and you dislike your partner, this probably isn’t going to fix a ton. It might help 6:05 a little bit, but that’s not what it’s meant for. So, you really have to know what you’re using it for and why. And 6:11 the other thing that I would say is this is something that we don’t go to if your hormones are not balanced properly. You 6:17 have to balance your hormones properly before using something like this because it still may not work. Now, the only 6:24 caveat to that is if you’re a woman that has a risk of breast cancer and can’t use hormones, then that’s a different 6:31 story and we would have that conversation about whether or not this medication would be appropriate for you. Now, the FDA label specifies PTA1 uh 6:39 PT-141 as it not being indicated for HSDD in causes where low sexual desire 6:46 is due to coexisting medical or psychiatric conditions, problems with relationships, like we had talked about, 6:53 side effects to medications or other substance use. This specifically reflects the importance of differential 6:59 diagnosis. Low sexual desire can have many root causes and PT-41 is only 7:05 appropriate when those causes have been ruled out. Now, I have I used PT41 in 7:10 people who have sexual dysfunction issues as a result of using 7:16 anti-depressants. Yes, I have. I’ve used Flynn in that effect as well. And it 7:21 does work sometimes, but it doesn’t work completely. But you need to know that that is not what the approval is for the 7:27 FDA. So that is done in something that we call off label use. So very important 7:33 to know. Now in these clinical trials leading to FDA approval, this was published by Kinsburg and colleagues in 7:40 obstetrics and gyne gynecology in 2019. PT-141 demonstrated statistically 7:46 significant improvements in sexual desire and decreases in distress related 7:51 to low desire compared to placebo. The effects manifest over 45 minutes to 7:56 several hours after the injection and the mechanisms involved modulation of dopamine and melanoorton pathways in the 8:04 hypothalamus and the brain regions that involved sexual motivation. Now cardiovascular effects of PT 141 require 8:12 careful attention. This drug causes transient increases in blood pressure about 3 to four points and transient 8:20 decreases in heart rate. And because of this, it is contraindicated in patients 8:25 with uncontrolled hypertension or known cardiovascular disease. And it has been studied in patients who’ve had recent 8:32 cardiovascular events or sorry hasn’t been studied hasn’t been studied in patients who’ve had recent 8:39 cardiovascular events. So patients need to have their blood pressures checked before starting therapy. Nausea is 8:45 extremely common. It is one of the biggest things I often will tell people to take an anti-nausea medicine if 8:52 they’re going to do this because the last thing you want to do is inject this medication and think it’s going to give 8:57 you this great time with your partner and you’re so nauseated that you can’t even perform, don’t want to kiss, don’t 9:05 want to do anything. It it can be pretty profound for some people. um it does affect about 40% of the patients in 9:12 clinical trials which is why many clinicians require or recommend an 9:17 anti-nausea medication like I had just said other common adverse effects include flushing injection site 9:24 reactions headache in about 13% of the population which I have seen worse if 9:30 people are prone to headaches and the headaches are pretty intense so I will also have them premedicate if they have 9:36 that um sensitivity ity with a Tylenol or Advil, Alie, whatever it is they 9:42 typically use for their headaches to help prevent that from occurring. Now, some patients also experience a 9:50 generalized hyperpigmentation of their skin, particularly in areas with chronic friction, and this may not be reversible 9:57 after discontinuation. So from an integrative perspective, PT-41 10:03 represents one tool in addressing female sexual dysfunction, but it should never be the first or only intervention. And 10:11 low sexual desire in women is complex. Multiffactorial involving hormonal imbalances, low testosterone, estrogen 10:18 deficiency, progesterone imbalances, thyroid dysfunction, adrenal dysfunction, and with elevated or 10:24 disregulated cortisol levels, sleep deprivation, relationship issues, unresolved trauma, including sexual 10:31 trauma, chronic pain, body image concerns, and medication side effects such as SSRIs are notorious for this. So 10:39 a comprehensive hormone panel including total and free testosterones, estradile, 10:45 progesterone, DHEA, thyroid function in cortisol assessment, ideally four-point 10:51 cortisol, salivary should precede any pharmacological intervention. And additionally, addressing the 10:57 psychological component and relationship dimensions through appropriate therapy is necessary. I have a lot of patients 11:03 that say, “This is just too much work for sex. I don’t want the side effects. I don’t want to deal with this.” and that’s totally fine. But for some 11:09 people, their sexual dysfunction is actually causing more problems on their 11:14 relationship and they want to do something to fix that. And just know that if you’re using a peptide like this 11:20 that comes with some of these side effects and you have to premedicate for it, it is not the end of the world. Um, 11:27 but it may be a possibility that you may need that. So, let’s dive into body composition and growth hormone access. 11:34 So Tesmarellin is the only FDA approved GH 11:40 analog. Tesarelin is marketed as Agrifta and Agria SV. It is a synthetic analog 11:48 of human growth hormone releasing hormone. So GH RH human growth hormone 11:53 releasing hormone. These things are such long names it’s confusing and it’s difficult to spit out, right? It 11:59 consists of 44 amino acids. The structure is identical to our own 12:05 body’s growth hormone GHR um with the addition of trans3 hexonol group which 12:14 stabilizes the molecule that extends its half-life compared to the native GHR. 12:19 The mechanism of tesmarellin is elegant in its preservation of physiological 12:24 growth hormone GH secretion patterns and rather than administering an exogenous 12:30 growth hormone directly, tesmarillin binds to the GH receptor in the anterior 12:36 pituitary gland stimulating the indogenous pulsatile release of GH. So 12:42 you know it it’s slower in that stimulation and it pulsates instead of a direct rise and fall. This pusile 12:49 pattern more closely mimics natural GH secretion which occurs in bursts 12:54 primarily during sleep. The GH then stimulates the liver to produce insulin-like growth factor IGF-1 which 13:01 exerts many of the downstream metabolic effects including lipolytic effects on 13:07 the atapost tissue. So fat atapose and how we break that down. The FDA approved 13:13 tesmarellin in 2010 for a very specific narrow indication, the reduction of 13:19 excess abdominal fat in HIV infected patients with lipodistrophe. This 13:25 condition characterized by abnormal fat redistribution with accumulation of visceral body fat and the loss of 13:32 subcutaneous fat in face and limbs developed as a complication of an 13:37 antiviral therapy particularly with older protease inhibitor reg uh 13:42 regimens. The visceral fat accumulation in patients is not just cosmetic. It’s associated with increased cardiovascular 13:49 risk, insulin resistance, and inflammatory markers. The pivotal trial that led to the FDA approval included 13:56 work by Stanley and colleagues published in the annuals of internal medicine in 2014. It demonstrated that tesmarillan 14:03 significantly reduced the visceral atapose measured by CT scan by approximately 15 to 20% which is a 14:10 significant difference to placebo over a short period of time only 26 weeks. Now, 14:16 interestingly, the total body uh weight typically remained stable or even 14:21 increased slightly as the reduction of visceral fat was sometimes offset by increases in lean body mass or 14:28 subcutaneous fat. This highlights an important point. Tesmearellin is not a weight loss drug in its conventional 14:34 sense. Its effects are specifically on body composition and fat redistribution. 14:40 Now the glucose metabolism effects of tesmarellin do require careful monitoring because GH and IGF1 can 14:47 induce insulin resistance. Tesmearellin can increase glucose levels and hemoglobin A1C and in these clinical 14:54 trials glucose tolerance and new onset diabetes occurred in some patients. So 14:59 this creates a therapeutic paradox while res reducing visceral fat we should theoretically improve metabolic health. 15:07 The GH mediated insulin resistance can worsen the glycemic control and patients 15:12 with diabetes require particularly close monitoring. The potential need for adjustment in diabetic medications can 15:19 occur. So I already know what you guys are thinking. Can I use Tesmarellin and 15:24 GLP1 at the same time? And the answer is yes. Especially in those people that we 15:30 know have an insulin resistance already or are prone to that, we can use lowd 15:36 dose micro doing GLP-1 along with tesmarellin to help prevent this from 15:42 occurring um or reduce the risk of it occurring. Now there are some other adverse related problems to growth 15:49 hormone access which include fluid retention which can uh manifest as uh 15:55 ankle swelling, joint pain, muscle pain, paristhesas, carpal tunnel syndrome is 16:01 common to see. Of course you can always see injection site reactions reported about 26 to 30% of the time in the trial 16:08 participants. And this also theoretically has a concern about IGF-1 elevation potentially promoting 16:14 malignancy through long-term data is limited. So we have to be cautious about 16:20 this but it is a growth hormone and anything that is a growth hormone can cause cells to grow and it cannot 16:26 necessarily differentiate between healthy cells and bad cells. So the drug is contraindicated is contraindicated in 16:33 patients with active cancer and in patients with the disruption of the HPA access from conditions like pituitary 16:40 tumors, pituitary surgery, head of radiation um and traumatic brain injury. 16:46 Now off label use of tesmarellin for general anti-aging or body composition 16:51 optimization in non-HIV population, it doesn’t have FDA approval. There is no 16:58 FDA studies. um that promote this, but practitioners do prescribe it for these 17:04 purposes under an experimental and not supported by FDA approved indications. 17:10 And um from an integrative medical standpoint, optimizing natural growth 17:15 hormone secretion through lifestyle interventions, high quality sleep is important. GH primarily is excreted 17:22 during sleep and deep sleep waves. So improving your deep sleep is important. Intermittent fasting can also increase 17:28 growth hormone by five-fold as demonstrated in a Hartman and colleagues uh study from the journal of clinical 17:35 endocrinology and metabolism in 1992. And highintensity interval training, adequate dietary protein, blood sugar 17:42 control, these all can help naturally increase your growth hormone. So, let’s 17:47 dive in now and talk about bone health. peptide hormones um such as oh I’m gonna 17:54 I’m gonna really slaughter this name. Terraparatide is a true bonebuilding 18:01 peptide. It’s marketed as forio. It’s a recumbent form of the first 34 amino 18:08 acids out of 85 of the human parathyroid hormone PTH. It represents a unique 18:13 approach to osteoporosis treatment because it’s one of the few truly anabolic anabolic bone therapies meaning 18:21 it actively binds new bone rather than simply preventing bone loss. The biology 18:26 of parathyroid is fascinating and seemly contraindicated or uh contradictory. 18:32 Continuously sustained elevations of PTH as occurs in hyperarathyroidism 18:37 is catabolic to bone. So people who have hyperarothyroidism typically have significant bone loss 18:44 especially before it’s diagnosed and it causes causes increased bone 18:49 reabsorption loss of bone density increased fracture risk and however 18:55 intermittent exposure to PTH as achieved with once daily uh injections of forio 19:01 has the opposite effect. This intermittent exposure preferentially stimulates osteoblasts bone building 19:08 cells over osteoclasts bone reabsorbing cells and it leads to 19:13 the net bone formation. So terraparatide binds to the PTH receptors on 19:20 osteoblasts and renal tubular cells in bone. It increases the number of 19:25 activity of osteoblasts stimulating the differentiation of osteoblast precursor cells and may 19:32 reduce osteoblast apoptosis basically programmed cell death allowing this bone 19:37 building cell to work longer. The result is increased bone formation, improved bone architecture and tbacular 19:45 connectivity and ultimately increased bone mineral density um particularly in the hip and the spine which is so 19:51 difficult to regain. The FDA approved this medication in 2002 based on pivotal 19:57 studies by Near and colleagues published in the New England Journal of Medicine in 2001 which demonstrated significant 20:05 reductions in vertebral and non-vebral fractures in post-menopausal women with 20:11 osteoporosis. specifically uh reduced new vertebral fractures by 20:17 65% and nonvettebral fragility fractures by 53% 20:23 compared to placebo over a median followup of 21 months. This is really 20:29 incredible because we have not seen this kind of um change uh in other 20:35 medications that we’ve used for osteoporosis. So current FDA approval 20:40 indicates uh this for post-menopausal women with osteoporosis at high risk for 20:46 fracture, men with primary or hypoconatal osteoporosis at high risk for fracture 20:53 and men and women with glucocord cord glucocordide 21:00 induced osteoporosis at high risk for fracture. The high risk qualifier is 21:05 important. uh terrapeptide is reserved for patients with severe osteoporosis, 21:11 multiple fractures, very low low bone density and those who have failed or are 21:16 intolerant of other therapies. The most significant concern for this medication 21:21 is highlighted in a boxed warning with rat toxicology studies where it caused 21:27 osteioaroma which is a bone cancer in a dose dependent and treatment duration dependent manner. The revolence of this 21:34 finding to humans is debated. Rats have fundamentally different bone biology than humans with continuous bone growth 21:41 throughout life and different PTH receptors. Now post marketing 21:46 surveillance in humans hasn’t shown a clear increase in osteocaroma risk but 21:51 theoretically concerns persist and because of this terapeptide is 21:57 contraindicated in patients at risk baseline risk for osteioaroma 22:02 including those with pageantss disease of the bone unexplained elevations of alkaline phosphate prior skeletal 22:10 radiations bone metastases or skeletal malignancies and pediatric patients or young adults 22:16 with open hyes. There’s also a lifetime treatment duration of only 2 years and 22:22 terrapeptide can cause transient hypercalcemia. So an elevated blood calcium and as PTH normally increases 22:31 calcium levels by enhancing bone reabsorption, increasing renal calcium 22:36 reabsorption and promoting activation of vitamin D which increases intestinal calcium absorption. Some patients 22:43 experience orthostatic hypotension within 4 hours of injecting requiring 22:48 caution in at risk populations for blood pressure. Common side effects include 22:53 muscle pain, joint pain, pain in the limbs, nausea, headache, and dizziness. So from an integrative bone health 23:00 perspective, terrapeptides should be part of a comprehensive strategy. Adequate calcium intake, 500 to a,000 23:08 milligrams of calcium a day from food and supplements combined. and vitamin D. 23:13 Getting vitamin D levels of at least 50 to 80 are essential for the drug to work 23:20 optimally. But beyond this, bone health requires vitamin K2, which directs calcium into the bones rather than soft 23:27 tissues, magnesium as a co-actor in bone metabolism, trace minerals like boron, 23:33 copper, silica, and of course, adequate protein intake, which many of us, especially as women, don’t do 0.8 8 to 1 23:42 gram of protein per kilogram of body weight, weightbearing exercise. Of 23:47 course, these all provide mechanical signals that complement the biochemical 23:52 symbol uh signals of terrapeptide. Sequential therapy is also critical. The 23:58 bone mass gains from terraparatide can be lost if patients don’t transition to 24:05 an anti-resorbbitive agent a bisphosphinate after completing this therapy and the anabolic effects to 24:12 build bone but maintaining the new bone requires preventing excess reabsorption. 24:18 So positive things about this but there are definitely some concerns as well. So 24:23 the next one we’re going to talk about is Lu Prolrooide. It is marketed under 24:29 the multiple brand names of Lupron, Depo, Eligard, and it’s a synthetic 24:34 nonapeptide analog of naturally occurring ginonadotropen releasing 24:39 hormone G&R, also called luteinizing hormone releasing hormone, LHR. 24:46 It’s a fascinating example of how manipulating natural hormonal feedback systems can create therapeutic effects. 24:53 So, G&RH is normally secreted in a pulsatile fashion by the hypothalamus 24:59 and travels to the anterior pituitary where it binds to G&R receptors and 25:05 stimulates the release of luteinizing hormone LH and follical stimulating hormone FSH. These ginatotropins signal 25:13 the ovaries or the testes to produce sex hormones, estrogen, progesterone in 25:18 women, testosterone in men. Uh, luoprololi lupron as a GNR agonist 25:26 initially mimics the action of natural G&R causing an acute flare response with 25:33 uh increased LHFSH secretion which temporarily increases sex hormone 25:38 production. However, the continuous administration which is in the depo 25:44 formulations, the GNR receptors in the pituitary become desensitized and 25:50 downregulated. And after about 2 to four weeks of continuous exposure, LH and FSH 25:56 secretion is profoundly suppressed, leading to what’s termed as chemical 26:01 castration. Testosterone levels in men drop to castrated levels less than 50 26:08 and estrogen production is marketkedly suppressed in women. This bifphasic 26:13 response creates both therapeutic applications and management challenges in prostate cancer where tumor growth is 26:20 typically androgen dependent and the ultimate goal is testosterone suppression. However, the initial 26:27 testosterone surge during the flare phase can temporarily worsen symptoms potentially causing increased bone pain, 26:34 urinary obstruction, or even spinal cord compression in patients with metastatic 26:40 disease. This is why uh luoprolide is often started with an anti-ad androgen 26:47 like bicladamide for the first two to four weeks to block the effects of the 26:52 testosterone surge. The FDA has approved lupalide for multiple indications across 26:59 formulations. In oncology, it’s used for palletive treatment of advanced prostate cancers. In gynecology, various 27:06 formulations are approved for endometriosis, for pain management and lesion reduction and for fibroids. 27:13 Typically for pre-operative uh hematological improvement in anemic patients. In pediatrics, it’s used for 27:20 central precocious p puberty basically to halt the premature sexual development of these young people. Now, there are 27:28 adex uh adverse effect profile that reflects profound hormonal suppression. 27:34 In men treated for prostate cancer, hot flashes affect about 59% of the patients. Other common effects include 27:41 general pain, swelling, bone pain. Um long-term use of these medications leads 27:47 to metabolic changes. It increases fat mass. It decreases lean mass. It worsens 27:53 insulin sensitivity, disrupts the cholesterol uh lipid panels, increases 27:59 diabetic risk, has some concerns over cardiovascular disease. And the metaanalysis have shown increased risks 28:06 of heart infarction, myocardial inffection, sudden cardiac death, and stroke in populations receiving 28:13 long-term androgen deprivation therapy. The bone effects are particularly dramatic. Without sex hormones, bone 28:20 density decreases significantly, typically 3 to 4% per year during the 28:26 first two to three years of therapy. And this bone loss may not fully be reversible after the the therapy 28:32 discontinues. The American Society of Clinical Oncology recommends bone density monitoring and consideration of 28:39 bisphosphinates uh in men receiving long-term androgen deprivation. In women treated for 28:46 endometriosis or fibroids, the estrogen suppression creates a hypoestrogenetic state similar 28:54 to menopause. Hot flashes affect 90% of patients with other common effects 29:00 including headaches, emotional irritability, decreased sex drive, vaginal dryness, bone density loss. And 29:08 because of these bone concerns and treatment duration with endometriosis, typically limited to six months, though 29:14 some formulations allow for longer use with adback hormonal therapy to 29:20 partially mitigate these side effects. The mood and cognitive effects can be s 29:25 significant. I’ve seen it over the years. the depression, the memory impairment, difficulty focusing and 29:31 concentrating. It can be very very traumatic and the quality of life that 29:37 happens for these uh women and men can be unbearing for many of them. Um, from 29:44 an integrative perspective, patients receiving this medication need comprehensive support care. Bone health 29:51 interventions using calcium, vitamin D, vitamin K2, weightbearing exercise, 29:58 cardiovascular risk management becomes critical, including blood pressure monitoring, lipid management, diabetes 30:05 screening. For hot flashes management, some patients respond to black coohos, 30:10 sage, or vitamin E. Though evidence is mixed and individual response varies, 30:16 omega-3s may help with the mood and the inflammation, resistance training becomes specifically important to 30:22 preserve lean muscle mass in the face of hormonal suppression. 30:27 Now there’s something called calcetonin salamon which is marketed as miaelin. 30:34 It is a nasal spray. It is now discontinued. And foral is the new 30:39 synthetic polyeptide hormone of 32 amino acids identical to calcetonin of salamon 30:47 origin. It represents an interesting case study in how initial promise gives 30:52 way to safety concerns that regulate a therapy to historical footnote status. 30:58 Calcetonin is naturally occurring hormone in humans. It’s secreted by the paraphalicular sea cells in the thyroid 31:04 gland. Its primary physiological role is to lower blood calcium levels by 31:10 directly inhibiting osteoclast activity, reducing bone reabsorption, increasing 31:16 renal calcium secretion or excretion, and possibly reducing the intestinal 31:21 calcium absorption. So, salamon calcetonin is used therapeutically because it’s more potent and longer 31:27 acting than human calcetonin. The FDA initially approved calceton and salmon 31:34 for several indications post-menopausal osteoporosis in women more than five 31:39 years post-menopausal when alternative treatments are not sustainable. Padet’s 31:44 disease for bone and hypercalcemium as emergency treatments. The nasal spray formulation is particularly popular for 31:53 osteoporosis because it offered a non-injectable alternative to bisphosphinates. 31:58 However, in 2012, the European Medicine’s Agency, EMA, conducted a 32:05 comprehensive safety safety review after a poolled analysis of 21 clinical trials 32:10 involving over 10,000 patients showed a statistically significant increase in 32:15 malignancy risk in patients treated with calceton salamon compared to compared to 32:21 placebo. The overall malignancy rate was 4.1% in calcetonin treated patients 32:28 versus 2.9% in placebo patients. The types of cancer 32:34 varied with no single cancer type predominating, making it difficult to establish a clear mechanistic link. 32:41 However, the signal was concerning enough that the EMA restricted the use of calcetonin containing medicines. In 32:48 the United States, the FDA issued communications about malignancy signal and conducted its own review. While they 32:56 didn’t fully withdraw the drug, the cons consensus shifted dramatically. The nasal spray formulations miaelson was 33:03 voluntarily discontinued by the manufacturer and current clinical practice guidelines now consider 33:10 calcetonin salamon as a second line or lower option for osteoporosis. While 33:15 behind bisphosphinates, dennism mob, uh, terrapeptide, the analesic effect of 33:21 calcetonin in bone pain, particularly in acute vitibbral, uh, compression 33:26 fractions from osteoporosis or pageantss disease may still provide a role for short-term use in these selected 33:32 patients. The mechanism of this pain relief is unclear, but may involve 33:38 effects of endorphin systems and/or direct actions on pathways. The history serves as an important reminder in 33:45 peptide medicine. Initial approval and early clinical use does not guarantee 33:50 long-term safety effects. Post marketing surveillance and poolled analysis of the clinical trial data can reveal adverse 33:58 effects that weren’t apparent in initial studies. It also underscores why newer 34:04 agents with better safety profiles um have largely replaced calcetonin in 34:10 clinical practice. So this is really an important thing. Not one thing stays the same forever. We have to change as we 34:18 identify new and better products as we identify problems and concerns. I will 34:24 always tell my patients if you are uncertain of taking a new drug which we 34:30 all should be wait five years. Within five years we are going to find the 34:36 problems that they didn’t find in the clinical studies. Remember, a lot of these clinical studies are small, small 34:43 groups, short periods of time. It’s expensive to do these trials. So, if you 34:49 wait for five years, in the first two to three years, you will see the problem start to emerge. And what are you going 34:55 to look for? You’re going to look for the the news um commercials from lawyers 35:02 suing a drug. And they will tell you what the problem is. and then you can decide, is this something that I want to 35:09 use or not. Don’t jump on bandwagon and be the first one to do this, especially 35:14 if you’re sensitive. You know, give it time so you can see exactly what’s going on. So, I’m going to end our show on 35:22 this and we are going to pick up on part three of peptide therapy in our next 35:28 segment where we’re going to talk about the investigational peptides and some 35:34 exciting things that are happening with that. So, I want to thank you for joining me today on Let’s Talk Wellness 35:39 Now. It’s always a pleasure having a conversation with you guys and I hope this brings value to you with what we’re 35:45 talking about. If you have ideas for topics that you want me to discuss, 35:51 please message us, you can share your comments on Facebook, you can email us, 35:58 um you can get a hold of us however you would like to share that. I do look at the comments below in the episodes as 36:04 well. So you can place your comments there. And once again, one of the best things you can do for me is like, 36:11 subscribe, and share so that we can spread the messages of what we’re doing. 36:16 I do this at no cost. I don’t make any money out of this. I do this as an 36:21 educational purpose for everybody else. I love doing it, but it really helps us 36:28 on the algorithms if you would be just willing to like, subscribe, and share. 36:33 So, thank you for spending your time with me. I know time is important.The post Episode 257 – Peptides for Sexual Wellness & Hormonal Health: PT-141, Growth Hormones, Bone Health & More! first appeared on Let's Talk Wellness Now.
Amor Nas Redes é um quadro do canal Não Inviabilize. Aqui você ouve as suas histórias misturadas às minhas!Use a hashtag #EsmolaDemais e comente a história no nosso grupo do telegram: https://t.me/naoinviabilizePUBLICIDADE CLEARBLUECom o Clearblue Teste de Gravidez Digital, você tem mais de 99% de precisão¹ e também a informação de quantas semanas². Descubra seu ritmo com Clearblue.Aviso:¹Mais de 99% de precisão na detecção da gravidez a partir do dia esperado damenstruação. ²Semanas desde a concepção exibidas como 1-2, 2-3 ou 3+ [na tela]Declaração regulatória:Mais de 99% de precisão a partir do dia do início esperado da menstruação. Maisde 99% de precisão na detecção do aumento do LH.Sempre consulte seu médico e leia as instruções. Registro ANVISA No: 80686360214,80686360215, 80686360212, 80686360213 80686360275#Publicidade #ClearblueConfirma #ParceriaClearblueQUER OUVIR MAIS HISTÓRIAS? BAIXE NOSSO APLICATIVO EM SUA LOJA APPLE/GOOGLE, CONHEÇA NOSSOS QUADROS EXCLUSIVOS E RECEBA EPISÓDIOS INÉDITOS DE SEGUNDA A QUINTA-FEIRA: https://naoinviabilize.com.br/assineEnvie a sua história bem detalhada para naoinviabilize@gmail.com, seu anonimato será mantido, todos os nomes, profissões e locais são trocados para preservar a sua identidade.Site: https://naoinviabilize.com.brTranscrição dos episódios: https://naoinviabilize.com.br/episodiosYoutube: https://youtube.com/naoinviabilizeInstagram: https://www.instagram.com/naoinviabilizeTikTok: https://www.tiktok.com/@naoinviabilizeX: https://x.com/naoinviabilizeFacebook: https://facebook.com/naoinviabilizeEdição de áudios: Depois O Leo Corta MultimídiaVinhetas: Pipoca SoundVoz da vinheta: Priscila Armani
In this episode, I sat down with Rose MacKenzie, Clinical Manager at Mira, to discuss hormone tracking and why it matters from puberty through menopause. Rose has over a decade of experience as a natural family planning instructor and has helped countless women understand their hormonal patterns. Key Topics: Why hormone tracking matters at every age If you have functioning ovaries, your hormones fluctuate and impact everything about you The limitations of period tracking apps Most apps use outdated calendar methods and only 4 out of 74 studied apps were actually accurate How the Mira fertility tracker works An at-home hormone monitoring system that tracks estrogen, LH, progesterone, and FSH through urine testing My personal experience At 46 and in perimenopause, I've been using Mira for two months and the data has been fascinating Understanding perimenopause Why this phase is so confusing and how tracking can give you back control Failed ovulation attempts What happens when your body tries to ovulate but doesn't succeed (common in perimenopause, PCOS, and postpartum) Timing progesterone supplementation Why taking it on a set day (like day 14) might not align with YOUR body's actual ovulation The importance of FSH Why this often-ignored hormone deserves more attention, especially 6+ years before menopause Who can benefit from tracking From teens to postmenopausal women, including those who've had hysterectomies or ablations Let's dive in! Thank you for joining us today. If you could rate, review & subscribe, it would mean the world to me! While you're at it, take a screenshot and tag me @jennpike to share on Instagram – I'll re-share that baby out to the community & once a month I'll be doing a draw from those re-shares and send the winner something special! Click here to listen: Apple Podcasts – CLICK HERESpotify – CLICK HERE Connect with Guest - Instagram | @mirafertility Facebook | @mirafertility Website | miracare.com | Use code "2JENNPIKE20" at checkout for 20% off your order This episode is sponsored by: withinUs | Use the code JENNPIKE20 at withinus.ca for a limited time to save 20% off your first order and 20% off your first subscription order St. Francis | Go to stfrancisherbfarm.com and save 15% off your all your orders with code JENNPIKE15 Eversio Wellness | Go to eversiowellness.com/discount/jennpike15 and save 15% off every order with code JENNPIKE15 /// not available for "subscribe & save" option Free Resources: Free Perimenopause Support Guide | jennpike.com/perimenopausesupport Free Blood Work Guide | jennpike.com/bloodworkguide The Simplicity Sessions Podcast | jennpike.com/podcast Get 20% on thewalkingpad.com using code "JENNPIKE20" Get discounts at happybumco.com using code "JENNPIKE" *code doesn't apply with Black Friday sale* Programs: Ignite: Your 8-Week Body Transformation Program | https://jennpike.com/ignite The Peri & Menopause Project - Join the Waitlist | jennpike.com/theperimenopauseproject Synced Virtual Fitness Studio | jennpike.com/synced Services: Work With Jenn | https://jennpike.com/work-with-jenn/ Functional Testing | jennpike.com/testing-packages Business Mentorship | The Audacious Woman Mentorship: jennpike.com/theaudaciouswoman Connect with Jenn: Instagram | @jennpike Facebook | @thesimplicityproject YouTube | Simplicity TV Website | The Simplicity Project Inc. Have a question? Send it over to hello@jennpike.com and I'll do my best to share helpful insights, thoughts and advice.
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