American molecular biologist
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Bacteria have been around for billions of years. Could they have come up with complex behaviors that we just don't understand yet? Could they have their own language? Their own culture? Their own complex societies playing out right under, and in, our noses? Microbiologist Bonnie Bassler has been studying these questions for more than 30 years. She talks with Host Flora Lichtman about the wild world of bacterial communication, and how understanding microbes could help us understand ourselves.Guest: Dr. Bonnie Bassler, microbiologist at Princeton UniversityTranscript will be available after the show airs on sciencefriday.com. Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.
Today, Associate Professor of Biology Dr. Julia van Kessel of Indiana University will chat with us about how groups of bacteria can sense one another and carry out behavior as a collective…including some kinds of disease! Host: Mark O. Martin Guest: Julia van Kessel Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode An introduction to the horrific disease leprosy, caused by the quite strange organism Mycobacterium leprae. An overview of the Hansen Institute in Ethiopia. A solid overview of quorum sensing. A very interesting review article about quorum sensing. A video that two of my Bio350 Micronauts (including a former guest of our podcast, Dr. Ruth Isenberg) put together some years ago to illustrate the idea of quorum sensing. A very clear overview of quorum sensing by the highly energetic and brilliant Dr. Bonnie Bassler, one of the giants of this field. A #LuxArt show I organized a few years ago at Carleton College, where I encouraged students to create art by “painting” with luminous bacteria on Petri dishes. It is a true merger of art and science. Using Chromobacterium to “look” for quorum sensing molecules. I made this imperfect video to illustrate the concept. My old friend Vibrio harveyi, which Dr. van Kessel uses in her laboratory. Vibrio coralliilyticus, which causes coral diseases. If you are interested in learning about how some bacteria have what seems to be a molecular switchblade knife—the Type 6 Secretory System— to use against other bacteria or other organisms, the link above is a fine place to start. In addition, a Bio350 student of mine made a lovely Claymation video of the process some years ago. Here is Dr. van Kessel's faculty website at Indiana University in Bloomington. Here is the laboratory website—with excellent graphics and videos—of Dr. van Kessel's group. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com
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Bonnie Bassler is the Chair of the Molecular Biology Department at Princeton. In this episode, Bonnie talks about her passion for scientific inquiry, creativity, mentorship, and how the journey of discovery is about asking the right questions, distinguishing between what you can do and what you should do, and about embracing the unexpected. In our very lively and fun discussion, we explore the significance of asking "why" questions to fuel passion and curiosity – even if only the if/what/when/how questions lead to clear answers – and we explore the balance between chaos and control in the scientific process. And so while the pay might be bad and the hours long, the joy of doing science and living on the edge in a “nerdy kind of way” makes it all worthwhile.For more information on Night Science, visit https://www.biomedcentral.com/collections/night-science .
Siete millones de años después de separarnos de un ancestro común, humanos y chimpancés compartimos el 90-95% del ADN. Un ambicioso proyecto internacional ha desarrollado el mayor catálogo de ADN de primates (la secuencia de más de 800 individuos pertenecientes a 233 especies, casi la mitad de las que existen en el planeta). El estudio, publicado en un especial de la revista Science, revela características fundamentales de la evolución humana y aporta claves para identificar las mutaciones que causan enfermedades como el cáncer y también para la conservación de la biodiversidad. Hemos entrevistado Tomàs Marquès-Bonet, investigador ICREA en el Instituto de Biología Evolutiva (centro mixto del CSIC y la Universidad Pompeu Fabra), catedrático de Genética de esta Universidad, y líder de este estudio. Hemos informado del Premio Princesa de Asturias de Investigación Científica y Técnica a los estadounidenses Jeffrey Gordon, Peter Greenberg y Bonnie Bassler por sus logros en la búsqueda de nuevos tratamientos efectivos contra bacterias resistentes a antibióticos. Y de la concesión de los Premios Jaume I a Antonio Echevarren Pablos (Investigación Básica); Guillermina López Bendito (Investigación Médica); Carlota Escutia Dotti (protección del medioambiente); Daniel Maspoch Comamala (Nuevas Tecnologías); y Olympia Bover Hidiroglu (Nuevas Tecnologías). Isabel Fernández nos ha contado la incorporación de España a la infraestructura europea OPERAS, un proyecto para promover el conocimiento en abierto sobre Humanidades y Ciencias Sociales. Con testimonios de Elea Giménez, investigadora del Centro de Ciencias Humanas y Sociales del CSIC y presidenta del Comité Científico de OPERAS. Montse Villar nos ha hablado de las corrientes intergalácticas que alimentan de gas a lejanas galaxias. Con Jesús Zamora hemos reflexionado sobre los temores que provoca la inteligencia artificial. Y hemos reseñado los libros “La armonía de las células. Una exploración de la medicina y del nuevo ser humano”, de Siddhartha Mukherjee (Debate); y “Expanding universe. The Hubble Space Telecope” (Taschen). Escuchar audio
Esta semana se ha hecho público el Premio Princesa de Asturias de Ciencia y Tecnología, y este humilde servidor vuestro ha estado entre el jurado :) El premio ha reconocido los trabajos de Jeffrey Gordon, Peter Greenberg y Bonnie Bassler que han contribuido a entender el papel de las comunidades de microorganismos en nuestro planeta, y en particular las comunidades que habitan a los seres humanos: nuestra microbiota. Antes de estos trabajos se tendía a pensar en los microorganismos como seres esencialmente solitarios, o sin las herramientas necesarias para relacionarse entre ellos y con ningún otro ser vivo. Gracias a los esfuerzos de los premiados ahora sabemos que seres tan sencillos como las bacterias pueden realizar formas sencillas de "comunicación", que les sirven para coordinarse cuando forman una comunidad o para relacionarse con sus hospedadores, cuando viven dentro de otro ser vivo. Esto también significa que existe cierta cooperación entre esos microorganismos y los seres vivos que los rodean, así que ahora los vemos como grupos mucho más dinámicos capaces de llevar a cabo acciones colectivas. Para ayudarnos a contar todo esto contamos hoy en la sección con la ayuda de Ginés Morata, que también formó parte del jurado y es investigador en el Centro de Biología Molecular Severo Ochoa en Madrid, además de galardonado con el Premio Príncipe de Asturias en el año 2007. En este episodio también podéis escuchar la sección de Santi García Cremades, en la que nos propone un reto matemático relacionado con el crecimiento de una colonia de bacterias. Al final del episodio podéis encontrar la solución ;) Si queréis aprender más sobre las extraordinarias capacidades de los microorganismos podéis escuchar los episodios s03e10 y s04e06 de Aparici en Órbita, en los que tratamos el tema. También podéis encontrar episodios relacionados en nuestro pódcast hermano, La Brújula de la Ciencia: buscad los capítulos s08e33, s09e39, s05e24, s05e28, s07e36 y s11e29. En La Brújula os hemos contado también la historia de las orugas capaces de comer plástico que mencionamos en este episodio; la tenéis en los capítulos s06e37 y s09e24. Este programa se emitió originalmente el 8 de junio de 2023. Podéis escuchar el resto de audios de Más de Uno en la app de Onda Cero y en su web, ondacero.es
Siete millones de años después de separarnos de un ancestro común, humanos y chimpancés compartimos el 90-95% del ADN. Un ambicioso proyecto internacional ha desarrollado el mayor catálogo de ADN de primates (la secuencia de más de 800 individuos pertenecientes a 233 especies, casi la mitad de las que existen en el planeta). El estudio, publicado en un especial de la revista Science, revela características fundamentales de la evolución humana y aporta claves para identificar las mutaciones que causan enfermedades como el cáncer y también para la conservación de la biodiversidad. Hemos entrevistado Tomàs Marquès-Bonet, investigador ICREA en el Instituto de Biología Evolutiva (centro mixto del CSIC y la Universidad Pompeu Fabra), catedrático de Genética de esta Universidad, y líder de este estudio. Hemos informado del Premio Princesa de Asturias de Investigación Científica y Técnica a los estadounidenses Jeffrey Gordon, Peter Greenberg y Bonnie Bassler por sus logros en la búsqueda de nuevos tratamientos efectivos contra bacterias resistentes a antibióticos. Y de la concesión de los Premios Jaume I a Antonio Echevarren Pablos (Investigación Básica); Guillermina López Bendito (Investigación Médica); Carlota Escutia Dotti (protección del medioambiente); Daniel Maspoch Comamala (Nuevas Tecnologías); y Olympia Bover Hidiroglu (Nuevas Tecnologías). Isabel Fernández nos ha contado la incorporación de España a la infraestructura europea OPERAS, un proyecto para promover el conocimiento en abierto sobre Humanidades y Ciencias Sociales. Con testimonios de Elea Giménez, investigadora del Centro de Ciencias Humanas y Sociales del CSIC y presidenta del Comité Científico de OPERAS. Montse Villar nos ha hablado de las corrientes intergalácticas que alimentan de gas a lejanas galaxias. Con Jesús Zamora hemos reflexionado sobre los temores que provoca la inteligencia artificial. Y hemos reseñado los libros “La armonía de las células. Una exploración de la medicina y del nuevo ser humano”, de Siddhartha Mukherjee (Debate); y “Expanding universe. The Hubble Space Telecope” (Taschen). Escuchar audio
What role might the environment play on autoimmune diseases, like asthma? What could we learn about antibiotic use in pregnant women? Reproductive immunologist, and researcher, Dr. Melanie Conrad joins me to talk about these topics, and about the work she, and her team, are doing to uncover new information about how the immune system works! (0:00:45) Moving to Germany and accents. (0:02:42) Research and the study of asthma. (0:04:07) The journey to studying asthma. (0:06:22) Environmental causes of asthma and the role of traditional farms. (0:08:00) Generational studies and the Dutch Hunger Winter. (0:09:35) Why growing up on a farm can help your respiratory health. (0:11:35) The mouse model. (0:12:38) Mechanisms, contributing factors and the immune response. (0:14:08) The chronological study of the fetus, newborns and breast milk. (0:16:06) Moving from mouse to human: The ethics and physiology involved. (0:17:47) Fruit flies studies and why they are important. (0:19:02) Farm analysis and the chosen bacteria. (0:20:34) Urban environments and pollution: Getting back to nature. (0:22:36) The Protection Model and the Antibiotic Model. (0:24:30) Antibiotics: Not always the best solution. (0:25:31) Microbiome Analysis and the Antibiotic Model. (0:26:30) The importance of fetal development of microbiomes: Where they come from. (0:29:05) Pre and postnatal development of microbiomes and antibiotics. (0:30:55) Targeted antibiotics: Is it a possibility in the future? (0:32:00) Bonnie Bassler and Quorum sensing. (0:33:39) Antibiotics, Hives and Mites: A need for new research and advances. (0:35:09) Five more questions. (0:37:03) When does science become medicine? Research and medicine. (0:39:05) Open access and publishing. (0:40:17) Science and policy: The need for a middle person. (0:41:43) Science communication and Twitter. (0:43:31) What's next? Models, models models and metabolism. (0:45:35) PhD students. (0:46:15) Partner Acrobatics: A great hobby. (0:47:58) The cultural differences between Canada and Germany. (0:50:02) Being a scientist in Germany. (0:51:39) Berlin: Still loving it after over 10 years. Visit the Conrad Lab: https://www.conradlab.net/ Follow Melanie on Twitter: https://twitter.com/MLConradLab Visit Planet B612 on the web: http://planetb612.fm/ Follow Planet B612 on Twitter: https://twitter.com/PlanetB612fm
Networking should be purposeful. Otherwise, you're doing it wrong. This common networking mistake that people make is discussed by Scott Smith, a self-professed motivational speaker, and networking expert. Scott helps his clients get the most out of their networks through his 6-step science-based approach that relies on motivational listening and a part of the brain called the orbital cortex. You would not want to miss this episode because these are all important lessons that you can apply in the next networking event you're going to attend. Let's listen to Scott and easily build connections with new people! In this Episode: [00:01 - 07:28] Opening Segment Let's get to know Scott Smith His path to the networking space [07:29 - 18:27] Core of Networking What are you doing wrong in networking? Scott reveals Scott talks about the core of networking The difference between confidence and arrogance [18:28 - 28:00] Truth Behind Extroverts and Introverts Scott talks about clarifying questions and why you should ask them What to bring in a networking event according to Scott The truth behind extroverts and introverts [28:01 - 42:05] Traits of a Motivational Listener The unexpected question you'd want to ask in your next networking event Why you should know the history of other people How to become a motivational listener [42:06 - 46:35] Communicating Through Stories The conversation that left you with the most impact A high school conversation Communicating through stories What communication skill would you have wanted to learn sooner? writing The best communicators you know Dr. Bonnie Bassler [46:36 - 49:50] Closing Segment Connect with Scott! Links below Final words from me Tweetable Quotes: “Not everyone deserves a spot in your network.” - Scott Smith “That's part of what we're trying to do...differentiate between result and motivation.” - Scott Smith Resources Mentioned: FREE e-course to master body language and micro-expressions to boost your EQ by 10% and sales by 20%. Check it out https://bit.ly/3bGGN2Z (here). Scott's book: https://amzn.to/3r4907Q (Motivational Listener) TED Talk: https://bit.ly/2Qogjut (How bacteria “talk”) Email scott@dscottsmith.com to connect with Scott or follow him on https://bit.ly/3vM9J0T (LinkedIn), https://www.fb.com/dscott.magic (Facebook), https://twitter.com/d_scott (Twitter), and https://www.instagram.com/d.scottsmith/ (Instagram). Check out his https://www.dscottsmith.co/ (website) and learn more about his FREE e-course to “find the gold” on LinkedIn! You can connect with me on https://www.linkedin.com/in/gregricecxeffortgeek/ (LinkedIn), https://twitter.com/gregjrice (Twitter), https://www.instagram.com/gregjrice/ (Instagram), and https://www.facebook.com/gregory.rice.372/ (Facebook). Join https://www.facebook.com/groups/jointhecommunicationnation/ (The Communication Nation) and learn from others in the community. Feel free to email me at gregrice79@yahoo.com, I'd love to hear from you! Want more help with your digital marketing? Go to my website https://gregjrice.com/inflection/ (https://gregjrice.com/inflection/) and let's have a conversation. LEAVE A REVIEW + help someone who wants to expand their communication capacity by sharing this episode and listen to our previous episodes.
The molecular biologist Bonnie Bassler is deciphering the chemical languages that bacteria use to coordinate their assaults on a host. The post Bonnie Bassler on Talkative Bacteria and Eavesdropping Viruses first appeared on Quanta Magazine. The post Bonnie Bassler on Talkative Bacteria and Eavesdropping Viruses first appeared on Quanta Magazine
Hosted by Steven Strogatz, The Joy of x podcast is back with new episodes that explore the inner worlds of top-tier scientists and mathematicians like Frank Wilczek, Bonnie Bassler and Amie Wilkinson. The post Podcast Preview: The Joy of x, Season Two first appeared on Quanta Magazine. The post Podcast Preview: The Joy of x, Season Two first appeared on Quanta Magazine
This episode: Phages eavesdrop on bacterial communications to attack at the perfect moment! Thanks to Justin Silpe and Dr. Bonnie Bassler for their contributions! Download Episode (11.1 MB, 12.2 minutes) Show notes: Microbe of the episode: Artichoke Aegean ringspot virus News item Takeaways Even organisms as small as bacteria can, and often do, communicate with each other through a process called quorum sensing, in which each cell releases a small amount of a certain chemical into their surroundings. When the population is large enough that the concentration of this chemical builds up to a certain level, the cells in the population change their behavior. The specifics of this change depend on the species and the situation. But since this chemical signal is released into the environment, anything around that can sense it can listen in on the communications of a bacterial population. In this study, Justin Silpe and Dr. Bonnie Bassler find a type of virus that uses such a chemical communication as a signal to come out of stasis and hijack a whole population of bacteria at once! Journal Paper: Silpe JE, Bassler BL. 2019. A Host-Produced Quorum-Sensing Autoinducer Controls a Phage Lysis-Lysogeny Decision. Cell 176:268-280.E13. Other interesting stories: Bacteria around plant roots can affect when they flower (paper) Certain respiratory microbe communities seem to protect against flu New process for finding better electric bacteria Email questions or comments to bacteriofiles at gmail dot com. Thanks for listening! Subscribe: Apple Podcasts, RSS, Google Play. Support the show at Patreon, or check out the show at Twitter or Facebook
We pull back the curtain as former show hosts Merry Buckley and Carl Zimmer talk Meet the Scientist origins, favorite interviews and microbial topics. Julie’s Biggest Takeaways: Though the show started before podcasts were as popular as they are now, this didn’t pose a problem for Merry or Carl when soliciting guests - scientists were happy to have their work featured and to discuss their research. Inviting guests may involve bringing in a mix of experienced and early-career researchers, but both Merry and Carl agreed that the science is the major deciding factor when selecting guests. The ability to steer away from technical jargon and to use accessible, everyday analogies is one of the features shared by favorite guests. Carl uses the example of Bonnie Bassler, who explains bacterial quorum sensing as a communication mechanism. Delving into the personal motivations and experiences of guests can be tough, even when these experiences relate to science. Merry uses Abigail Salyers’ claim of the English teacher who supported her through her high-school pregnancy and Julie uses Ilaria Capua’s experience when falsely accused of trafficking viruses for money. Scientists can make themselves more visible to scientists and nonscientists by promoting their research on social media, particularly on Twitter. Links for this Episode: MTM Listener Survery Merry Buckley on twitter Carl Zimmer website Carl Zimmer on TWiV She has her Mother’s Laugh
Drugs that stop bacteria from talking might be new, powerful antibiotics – a much needed weapon in our never-ending struggle against bacterial infections. On the other hand, drugs that make bacteria chat more could boost the production of biofuels and other industrial goods that bacteria make for us. In 1990 a young Bonnie Bassler, mesmerized by glow-in-the-dark bacteria that could talk to their peers to coordinate light production, wondered whether other bacteria could talk too. The answer, she soon found out, was yes – including all the nasty bacteria that cause disease. Today, Bonnie Bassler is a professor in molecular biology at Princeton University and an authority in the field of bacterial communication. Her findings, that all bacteria can talk, revolutionized the way we think of bacteria and opened the doors to important medical and industrial applications. But the discovery of bacterial communication has given us much more than new drugs. It has shown us how bacteria live in the real world and forced us to reconsider our own human nature – if bacteria are talking, social beings too, how different are we from them after all? Prick your ears up and follow RadioScience on an exciting tour of the bacterial world and its chatty multilingual inhabitants - after which, we promise, you will never call bacteria boring again!
Läkemedel som hindrar bakterierna från att prata med varandra kan bli en ny sorts kraftfull antibiotika - ett vapen som vi verkligen skulle behöva i vår eviga kamp mot bakterieinfektioner. Å andra sidan skulle vi också ha nytta av att kunna få bakterier att prata mer med varandra. Till exempel för att boosta produktionen av biobränslen och annat som bakterier kan tillverka åt oss. 1990 började en ung Bonnie Bassler, som var helt uppslukad av att självlysande bakterier kunde prata med sina kompisar, och koordinera sitt lysande, undra om andra bakterier också kunde snacka med varandra. Svaret, som hon snart lyckades lista ut, var "ja". Det gällde även de otäcka bakterierna som orsakar sjukdomar. Idag är Bonnie Bassler professor i molekylärbiologi vid Universitetet i Princeton och en kändis inom forskningsfältet bakteriell kommunikation. Hennes upptäckter, att alla bakterier kan kommunicera med varandra, har revolutionerat synen på bakterier och öppnat dörrarna för nya viktiga medicinska och industriella tillämpningar. Utforskningen av bakteriernas prat har gett oss mer kunskaper om bakteriernas livsstil. Vi har blivit tvungna att ompröva vår egen natur - om bakterierna är sociala varelser som kommunicerar med varandra, hur mycket skiljer vi oss åt från dem? Följ med RadioScience på en spännande resa i bakteriernas värld och träffa de pratsamma flerspråkiga invånarna!
Eric Wieschaus, Squibb Professor in Molecular Biology at Princeton University, talks with Bonnie Bassler, his colleague at Princeton and the Editor of the Annual Review of Genetics, about his life and career. Dr. Wieschaus describes his beginnings as a young boy in Alabama, and recounts how his interest in science was sparked by a science camp in Kansas funded by the National Science Foundation when he was a teenager. After a bachelor's degree at Notre Dame, Dr. Wieschaus was admitted to graduate school at Yale University, where he studied under the direction of Swiss Developmental Biologist Walter Gehring. Dr. Gehring eventually returned to his home country, taking his student with him. In Basel, Dr. Wieschaus met Christiane Nüsslein-Volhard, or "Janni," as he calls her, and together they began the work that defined their careers. Their research resulted in the identification of 139 genes that determine the development of fruit fly embryos (Drosophila melanogaster), a finding that earned them the 1995 Nobel Prize in Physiology or Medicine jointly with Edward B. Lewis.
Bonnie Bassler is the world specialist in how bacteria communicate within the human body. She explains to A.C.Grayling and pupils at Haverstock School, that this process holds the key to solving the problem of failing antibiotics.
Dania Wright '14 explores quorum sensing, a method of bacterial communication, and its potential uses in healthcare. She focuses on research by Bonnie Bassler at Princeton which might offer a treatment for cholera.
No bacterium lives alone – it is constantly encountering members of its own species as well as other kinds of bacteria and diverse organisms like viruses, fungi, plants and animals. To navigate a complex world, microbes use chemical signals to sense and communicate with one another. Filmed live on January 28th, 2013, at ASM's headquarters, catch a glimpse into the fascinating language of bacteria with discussions by Bonnie Bassler, Princeton University, and Steven Lindow, University of California, Berkley. Dr. Bonnie Bassler, Princeton University Bonnie Bassler Ph.D. is a Howard Hughes Medical Institute Investigator and the Squibb Professor of Molecular Biology at Princeton University. The research in her laboratory focuses on the molecular mechanisms that bacteria use for intercellular communication. This process is called quorum sensing. Bassler's research is paving the way to the development of novel therapies for combating bacteria by disrupting quorum-sensing-mediated communication. Dr. Bassler was awarded a MacArthur Foundation Fellowship in 2002. She was elected to the American Academy of Microbiology in 2002 and made a fellow of the American Association for the Advancement of Science in 2004. Dr. Bassler was the President of the American Society for Microbiology in 2010-2011; she is currently the Chair of the American Academy of Microbiology Board of Governors. She is also a member of the National Science Board and was nominated to that position by President Barak Obama. The Board oversees the NSF and prioritizes the nation's research and educational priorities in science, math and engineering. Dr. Steven Lindow, University of California, Berkeley Steven Lindow Ph.D. is a Professor at the University of California, Berkley where his research focuses on various aspects of the interaction of bacteria with the surface and interior of plants. Dr. Lindow' s lab uses a variety of molecular and microscopy-based methods to study the ecology of bacterial epiphytes that live on the surface of plants as well as certain bacteria that are vascular pathogens of plants. They also study bacteria that live in and on plants that are fostered by consumption of the alkaloids produced by endophytic fungi. The longer-term goal of their research is to improve plants' productivity by achieving control of plant diseases through altering the microbial communities in and on plants. Dr. Lindow is a member of the National Academy of Sciences, and was elected to fellowship in both the American Academy of Microbiology and the American Association for the Advancement of Science in 1999.
No bacterium lives alone – it is constantly encountering members of its own species as well as other kinds of bacteria and diverse organisms like viruses, fungi, plants and animals. To navigate a complex world, microbes use chemical signals to sense and communicate with one another. Recorded live on January 28th, 2013, at ASM's headquarters, catch a glimpse into the fascinating language of bacteria with discussions by Bonnie Bassler, Princeton University, and Steven Lindow, University of California, Berkley.
No bacterium lives alone – it is constantly encountering members of its own species as well as other kinds of bacteria and diverse organisms like viruses, fungi, plants and animals. To navigate a complex world, microbes use chemical signals to sense and communicate with one another. Filmed live on January 28th, 2013, at ASM's headquarters, catch a glimpse into the fascinating language of bacteria with discussions by Bonnie Bassler, Princeton University, and Steven Lindow, University of California, Berkley. Dr. Bonnie Bassler, Princeton University Bonnie Bassler Ph.D. is a Howard Hughes Medical Institute Investigator and the Squibb Professor of Molecular Biology at Princeton University. The research in her laboratory focuses on the molecular mechanisms that bacteria use for intercellular communication. This process is called quorum sensing. Bassler’s research is paving the way to the development of novel therapies for combating bacteria by disrupting quorum-sensing-mediated communication. Dr. Bassler was awarded a MacArthur Foundation Fellowship in 2002. She was elected to the American Academy of Microbiology in 2002 and made a fellow of the American Association for the Advancement of Science in 2004. Dr. Bassler was the President of the American Society for Microbiology in 2010-2011; she is currently the Chair of the American Academy of Microbiology Board of Governors. She is also a member of the National Science Board and was nominated to that position by President Barak Obama. The Board oversees the NSF and prioritizes the nation’s research and educational priorities in science, math and engineering. Dr. Steven Lindow, University of California, Berkeley Steven Lindow Ph.D. is a Professor at the University of California, Berkley where his research focuses on various aspects of the interaction of bacteria with the surface and interior of plants. Dr. Lindow’ s lab uses a variety of molecular and microscopy-based methods to study the ecology of bacterial epiphytes that live on the surface of plants as well as certain bacteria that are vascular pathogens of plants. They also study bacteria that live in and on plants that are fostered by consumption of the alkaloids produced by endophytic fungi. The longer-term goal of their research is to improve plants’ productivity by achieving control of plant diseases through altering the microbial communities in and on plants. Dr. Lindow is a member of the National Academy of Sciences, and was elected to fellowship in both the American Academy of Microbiology and the American Association for the Advancement of Science in 1999.
In this podcast I talk to Bonnie Bassler, a professor at Princeton and the president-elect of the American Society for Microbiology. Bassler studies the conversations that bacteria have, using chemicals instead of words, Her research is not only helping to reveal how bacteria work together to make us sick, but also how we might interrupt their dialogue in order to cure infections. Related Projects: Measurement of the copy number of the master quorum-sensing regulator of a bacterial cell. Information processing and signal integration in bacterial quorum sensing.
Bacteria communicate with chemical languages that allow them to synchronize their behavior and thereby act as multi-cellular organisms. This process, called quorum sensing, enables bacteria to do things they canât do as a single cell, like successfully infect and cause disease in humans. Bonnie Bassler, Ph.D., the Squibb Professor of Molecular Biology at Princeton University and President-elect for the American Society for Microbiology, has been researching strategies that can interfere with quorum sensing and will hopefully yield novel antibiotics to prevent disease. In this episode of MicrobeWorld Video we present the full presentation Dr. Bassler gave at the Marian Koshland Science Museum in Washington, D.C. on June 18, 2009. Not only does Dr. Bassler explain the mechanisms of bacterial communication, but she also puts forth her theories on how we can disrupt this communication for human benefit.
Bacteria communicate with chemical languages that allow them to synchronize their behavior and thereby act as multi-cellular organisms. This process, called quorum sensing, enables bacteria to do things they canât do as a single cell, like successfully infect and cause disease in humans. Bonnie Bassler, Ph.D., the Squibb Professor of Molecular Biology at Princeton University and President-elect for the American Society for Microbiology, has been researching strategies that can interfere with quorum sensing and will hopefully yield novel antibiotics to prevent disease. In this episode of MicrobeWorld Video we present the full presentation Dr. Bassler gave at the Marian Koshland Science Museum in Washington, D.C. on June 18, 2009. Not only does Dr. Bassler explain the mechanisms of bacterial communication, but she also puts forth her theories on how we can disrupt this communication for human benefit.
Bacteria communicate with chemical languages that allow them to synchronize their behavior and thereby act as multi-cellular organisms. This process, called quorum sensing, enables bacteria to do things they canât do as a single cell, like successfully infect and cause disease in humans. Bonnie Bassler, Ph.D., the Squibb Professor of Molecular Biology at Princeton University and President-elect for the American Society for Microbiology, has been researching strategies that can interfere with quorum sensing and will hopefully yield novel antibiotics to prevent disease. In this episode of MicrobeWorld Video we present the full presentation Dr. Bassler gave at the Marian Koshland Science Museum in Washington, D.C. on June 18, 2009. Not only does Dr. Bassler explain the mechanisms of bacterial communication, but she also puts forth her theories on how we can disrupt this communication for human benefit.