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Welcome to The Business of Aquaculture Podcast, where we dive deep into innovation, sustainability, and strategy in the blue economy. This episode features James Yip KW, General Manager at AR Biotech Pte Ltd and Director at DaFang AI — two companies at the intersection of aquaculture and automation.James has led the development of two Vibrio detection devices for inland shrimp ponds within just two years, helping farmers combat one of the industry's most persistent challenges. With a career that spans from software to robotics, and leadership roles at organizations like A*Star, he brings a cross-disciplinary lens to aquaculture innovation.We dive into:Why Airobot isn't just another gadget, but a tool solving urgent human problems in farming and constructionThe unique hurdles of scaling AI technologies in a tightly regulated hub like SingaporeA bold look at the future of indoor air quality and aquaculture diagnostics in a changing worldIf you're curious how AI and robotics are shaping the future of aquaculture — from pond to platform — this episode is for you.Support the show
If you're struggling, consider therapy with our sponsor. Visit https://betterhelp.com/almanac for a discount on your first month of therapy.If you have questions about the brand relating to how the therapists are credentialed, their privacy policy, or therapist compensation, here is an overview written by the YouTube creators behind the channel Cinema Therapy that goes into these topics: https://www.reddit.com/r/cinema_therapy/comments/1dpriql/addressing_the_betterhelp_concerns_headon_deep/ Hey there Poison Friends! And Happy Mother's Day to all of our awesome moms out there! We need to talk about what is in the water. Mainly pools, hot tubs, rivers, creeks, lakes, oceans...okay, so all of it. I am specifically bringing to your attention the many icky microbes that can infect you if you are not careful to prevent them while swimming and while on vacation. Many of these (campylobacter, E. coli, Giardia, etc) simply cause gastrointestinal illness...though these can be deadly in severe cases especially those younger than five years of age, the elderly, and those with compromised immunity. There are other's however that can cause deadly pneumonia in just the right circumstances and necrotizing fasciitis and sepsis. People have lost limbs thanks to such microbes as Vibrio and other horrid bacteria lurking in these aquatic environments. Lastly, I want to talk about one of my greatest fears but also one of my favorite topics to discuss: Naegleria fowleri...the brain eating amoeba. This nasty little amoebas, if allowed, can make their way up the nose, and all the way into the brain where they will quickly start eating away and destroying tissue. It is usually always fatal and only a handful of people around the world have survived. Like Vibrio, this is thankfully a rare occurrence. Still, I would avoid getting warmer fresh water up your nose...or using tap water for your Neti pots...it could literally come back to bite you...in the brain. That was lame, I know. Thank you to all of our listeners and supporters! Please feel free to leave a comment or send us a DM for any questions, suggestions, or just to say, "hi."Support us on Patreon:patreon.com/thepoisonersalmanacFollow us on socials:The Poisoner's Almanac on IG-https://www.instagram.com/poisoners_almanac?utm_source=ig_web_button_share_sheet&igsh=ZDNlZDc0MzIxNw==Adam-https://www.tiktok.com/@studiesshow?is_from_webapp=1&sender_device=pcBecca-https://www.tiktok.com/@yobec0?is_from_webapp=1&sender_device=pcAlso, look for us on TikTok @poisonersalmanacp
Episode Summary Afreenish Amir, Ph.D., Antimicrobial Resistance (AMR) Project Director at the National Institute of Health in Pakistan, highlights significant increases in extensively drug-resistant typhoid and cholera cases in Pakistan and discusses local factors driving AMR in Asia. She describes the development and implementation of a National Action Plan to combat AMR in a developing country, emphasizing the importance of rational antimicrobial use, surveillance and infection control practice. Ashley's Biggest Takeaways AMR is a global and One Health issue. Pakistan has a huge disease burden of AMR. Contributing factors include, but are not limited to, overcrowding, lack of infection control practices, poor waste management practices and over-the-counter prescription practices. Promoting the rational use of antimicrobials is imperative at all levels—from tertiary care to primary care practitioners. Typhoid and cholera are high-burden infections in Pakistan, with typhoid being a year-round issue and cholera being seasonal. A holistic approach, involving various sectors and disciplines, is necessary in order to address the global AMR threat. Amir highlights the need for better communication and collaboration to bridge gaps and build trust between different organizations. Featured Quotes: I've been working at the National Institutes of Health for the last 7 years now. So, I've been engaged in the development and the implementation of the national action plan on AMR, and that gave me the opportunity to explore the work in the field of antimicrobial resistance. Reality of AMR in Pakistan [Pakistan] is an LMIC, and we have a huge disease burden of antimicrobial resistance in the country right now. A few years back, there was a situational analysis conducted, and that has shown that there is presence of a large number of resistant pathogens within the country. And National Institutes of Health, they have started a very standardized surveillance program based upon the global antimicrobial use and surveillance system back in 2017. And [those datasets have] generated good evidence about the basic statistics of AMR within the country. So, for example, if I talk about the extensively drug-resistant typhoid, typhoid is very much prevalent in the country. Our data shows that in 2017 there were 18% MDR typhoid cases through the surveillance data. And in 2021 it was like 60%. So that has shown that how the resistance has increased a lot. A number of challenges are associated with this kind of a thing, overcrowded hospitals, poor infection prevention and control (IPC) measures. So, there is AMR within the country—there's a huge burden—and we are trying to look for the better solutions. Local Factors Driving AMR Bacteria, they do not know the borders. We have a close connection with the other Asian countries, and we have a long border connected with the 2 big countries, which are Afghanistan and India and Bangladesh and China. So, we see that it's not limited to 1 area. It's not regional. It's also a history of travel. When the people travel from one area to the other, they carry the pathogen as a colonizer or as a carrier, and they can infect [other] people. So, it's really connected, and it's really alarming as well. You never know how the disease is transmitted, and we have the biggest example of COVID—how things have spread from 1 country to the other, and how it has resulted in a massive pandemic. AMR is similar. We have seen that it's not limited to 1 region. We are part of this global community, and we are contributing somehow to the problem. First, I'll talk about the health care infrastructure. We do have the capacities in the hospitals, but still, there's a huge population. Pakistan is a thickly populated country. It's a population of around 241 million. And with the increasing population, we see that the infrastructure has not developed this much. So now the existing hospitals are overcrowded, and this has led to poor infection control practices within the hospitals. The staff is not there. In fact, ID consultants are not available in all the hospitals. Infection control nurses are not available in all the hospitals. So, this is one of the main areas that we see, that there is a big challenge. The other thing that can contribute is the poor waste management practices. Some of the hospitals—private and public sectors—they are following the waste management guidelines—even the laboratories. But many of the hospitals are not following the guidelines. And you know that AMR is under one health. So, whatever waste comes from the hospital eventually goes to the environment, and then from there to the animal sector and to the human sector. [Another big] problem that we are seeing is the over-the-counter prescription of antimicrobials. There is no regulation available in the country right now to control the over-the-counter prescription of antibiotics. They are easily available. People are taking the antibiotics without a prescription from the doctors, and the pharmacist is giving the patients any kind of medicine. And either it is effective/not effective, it's a falsified, low-quality antibiotic for how long in duration antibiotic should be taken. So, there are multiple of things or reasons that we see behind this issue of AMR. Rational Use of Antimicrobials It is a complex process how we manage this thing, but what we are closely looking at in the country right now is that we promote the rational use of antimicrobials at all levels—not only at the tertiary care levels, but also at the general practitioner level. They are the first point of contact for the patients, with the doctors, with the clinicians. So, at this point, I think the empirical treatment needs to be defined, and they need to understand the importance of this, their local antibiograms, what are the local trends? What are the patterns? And they need to prescribe according to those patterns. And very recently, the AWaRE classification of WHO, that is a big, big support in identifying the rational use of antimicrobials—Access, Watch and Reserve list—that should be propagated and that should be understood by all the general practitioners. And again, I must say that it's all connected with the regulations. There should be close monitoring of all the antibiotic prescriptions, and that can help to control the issue of AMR. National Action Plan on AMR So, when I joined NIH, the National Election plan had already been developed. It was back in 2017, and we have a good senior hierarchy who has been working on it very closely for a long period of time. So, the Global Action Plan on AMR, that has been our guiding document for the development of the national action plan on AMR, and we are following the 5 strategic objectives proposed in the global action plan. The five areas included: The promotion of advocacy and awareness in the community and health care professionals. To generate evidence through the data, through the surveillance systems. Generation of support toward infection prevention and control services IPC. Promoting the use of antimicrobials both in the human sector and the animal sector, but under the concept of stewardship, antimicrobial consumption and utilization. Invest in the research and vaccine and development. So, these are some of the guiding principles for us to develop the National Action Plan, and it has already been developed. And it's a very comprehensive approach, I must say. And our institute has started working on it, basically towards recreating awareness and advocacy. And we have been successful in creating advocacy and awareness at a mass level. Surveillance We have a network of Sentinel surveillance laboratories engaged with us, and they are sharing the data with NIH on a regular basis, and this is helping NIH to understand the basic trends on AMR and what is happening. And eventually we plan to go towards this case-based surveillance as well, but this is definitely going to take some time because to make people understand the importance of surveillance, this is the first thing. And very recently, the Institute and country has started working towards the hospital acquired infection surveillance as well. So, this is a much-needed approach, because the lab and the hospital go hand in hand, like whatever is happening in the lab, they eventually reach the patients who are in the hospitals. Wastewater surveillance is the key. You are very right. Our institute has done some of the work toward typhoid and cholera wastewater surveillance, and we were trying to identify the sources where we are getting these kinds of pathogens. These are all enteric pathogens. They are the key source for the infection. And for the wastewater surveillance mechanism, we can say that we have to engage multiple stakeholders in this development process. It's not only the laboratory people at NIH, but we need to have a good epidemiologist. We need to have all the water agencies, like the public health engineering departments, the PCRWR, the environmental protection agencies who are working with all these wastewater sites. So, we need to connect with them to make a good platform and to make this program in a more robust fashion. Pathogens and Disease Burdon For cholera and typhoid within Pakistan, I must say these are the high burden infections or diseases that we are seeing. For typhoid, the burden is quite high. We have seen a transition from the multidrug-resistant pathogens to the extensively drug-resistant pathogens, which now we are left with only azithromycin and the carbapenems. So, the burden is high. And when we talk about cholera, it is present in the country, but many of the times it is seasonal. It comes in during the time of the small zone rains and during the time of floods. So, every year, during this time, there are certain outbreaks that we have seen in different areas of the country. So, both diseases are there, but typhoid is like all year long—we see number of cases coming up—and for cholera, it's mainly seasonal. Capacity Building and ASM's Global Public Health Programs Capacity building is a key to everything, I must say, [whether] you talk about the training or development of materials. I've been engaged with ASM for quite some time. I worked to develop a [One Health] poster in the local language to create awareness about zoonotic diseases. So, we have targeted the 6 zoonotic diseases, including the anthrax, including the Crimean-Congo hemorrhagic fever and influenza. And we have generated a very user-friendly kind of layout in the local language, trying to teach people about the source of transmission. What are the routes of transmission, if we talk about the CCHF? And then how this can be prevented. So, this was one approach. And then I was engaged with the development of the Learnamr.com. This is online platform with 15 different e-modules within it, and we have covered different aspects—talking about the basic bacteriology toward the advanced, standardized methods, and we have talked about the national and global strategies [to combat] AMR, One Health aspects of AMR, vaccines. So, it's a huge platform, and I'm really thankful to ASM for supporting the program for development. And it's an online module. I have seen that there are around more than 500 subscribers to this program right now, and people are learning, and they are giving good feedback to the program as well. We keep on improving ourselves, but the good thing is that people are learning, and they are able to understand the basic concepts on AMR. Links for This Episode: Experts Discuss One Health in Pakistan: Biosafety Education Inside and Outside the Lab. Explore ASM's Global Public Health Programs. Download poster about zoonotic disease in English or Urdu. Progress on the national action plan of Pakistan on antimicrobial resistance (AMR): A narrative review and the implications. Global diversity and antimicrobial resistance of typhoid fever pathogens: insights from 13,000 Salmonella Typhi genomes. Wastewater based environmental surveillance of toxigenic Vibrio cholerae in Pakistan. Point Prevalence Survey of Antimicrobial Use in Selected Tertiary Care Hospitals of Pakistan Using WHO Methodology: Results and Inferences. Overcoming the challenges of antimicrobial resistance in developing countries. Take the MTM listener survey!
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Matters Microbial #78: An EXTREME Close Up of the Squid-Vibrio Symbiosis February 13, 2025 Today, Dr Ariane Briegel, Professor and head of the Integrative Structural Cell Biology research unit at the Institut Pasteur in Paris, France, joins the #QualityQuorum to discuss some of the exciting findings of her research group studying how bacteria and the ever-popular Hawaiian bobtail squid work together at a molecular level—using cutting-edge cryo-electron tomography! Host: Mark O. Martin Guest: Ariane Briegel Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode The (somewhat venerable) “The Eighth Day of Creation” discussed in this episode. A lovely article about the much missed Dr. Esther Lederberg. Here is another I much enjoyed. A website devoted to Dr. Esther Lederberg. A fun video reminder of the symbiosis between Vibrio fischeri and Euprymna scolopes. A review of cryo-electron tomography as applied to the study of bacterial structures. A book coauthored by Dr. Briegel on the use of this technology to study cell-microbe interactions. A video on the topic of cryo-electron tomography. Another video by Dr. Briegel on this topic. An earlier episode of #MattersMicrobial with Dr. Briegel. An article by the Moore Foundation that supports the work of Dr. Briegel. A article describing how cryo-EM can be applied to whole organisms, like roundworms. Research websites for collaborators on this project, Dr. Edward Ruby and Dr. Margaret McFall-Ngai. Dr. Briegel's laboratory website. Dr. Briegel's academic website. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com
Dr. Rita Colwell is a pioneering scientist and professor at the University of Maryland and Johns Hopkins who has made groundbreaking contributions to microbiology and public health. She joins AMSEcast to discuss her experiences being the first woman to lead the National Science Foundation as well as her advanced research on Vibrio bacteria and cholera while founding CosmosID to improve rapid pathogen detection. During the 2001 anthrax attacks, she led a cross-agency effort to identify the spores, revolutionizing DNA sequencing techniques. Overcoming sexism early in her career, Dr. Colwell's achievements are detailed in A Lab of One's Own. Guest Bio Rita Colwell is a Distinguished University Professor with an appointment in the University of Maryland Institute for Advanced Computer Studies. Colwell is one of the world's leading researchers of cholera—a waterborne disease estimated by the World Health Organization to strike three to five million people annually, many of them young children. Her efforts to track and predict cholera outbreaks are multi-faceted, combining bioinformatics with the pioneering use of satellite imaging. She was one of the first scientists to employ remote sensing for disease prediction, as well as recognize the impact of climate change on the waterborne microbial world. Show Notes (0:35) About Dr. Rita Colwell (1:52) Dr. Colwell's irritation at people saying we need to interest more women in science (2:49) How Rita dealt with overt sexism and still found the determination to keep moving forward (3:56) What lead Dr. Colwell to marine biology and focus on Vibrio (6:20) How she ended up at the University of Maryland (9:31) Rita's groundbreaking work on cholera and obstacles in getting her findings accepted (15:03) How long it took the professional world for her findings to be accepted (18:49) Dr. Colwell's work as the director of the National Science Foundation (21:39) The role she played in the response to the 2001 anthrax attacks (26:03) The prospects for women in the business world (28:58) The cost of persistent sexism (30:41) Rita's thoughts on how to advance women in the science and business worlds (33:40) What's next for Dr. Colwell Links Referenced A Lab of One's Own: One Woman's Personal Journey Through Sexism in Science: https://www.amazon.com/Lab-Ones-Own-Personal-Journey/dp/1501181270
They're back! Infectious Diseases Clinicians and show hosts Drs. Vivian Vega and Jackie Sherbuk reflect on the last few weeks since Episode 4. In the face of devastating storm surge from Hurricane Helene, and severe wind and flooding from Hurricane Milton, the Tampa Bay Area and its medical centers experienced a back to back punch, separated by only two weeks. This left some hospitals flooded, beaches seriously eroded, streets filled with debris, power outages lasting as much as 5-7 days, and countless people with immersed or damaged homes. Vivian and Jackie open the show by discussing how their lives were affected by evacuation orders, "hurricane call," and the stress of--in the words of a local weatherman--"stalking the turtle." That is, stressfully following daily hurricane forecasts without knowing if its slowly changing track would take it over the Tampa Bay Area. Now that the storms have passed, the recovery will likely take weeks to months. And diseases directly related to storm waters and flooding, such as Vibrio vulnificus and mosquito-borne illnesses, will likely be on the rise. Next, as Florida begins to experience cooler weather in the wake of the storms, the duo go on to discuss the coming respiratory virus season. First, acknowledging the renewed thread of COVID-19, Vivian reviews the "alphabet soup" of influenza virus strains, how to decipher the H's and N's of flu season, and what is meant by "antigenic shift" and "angenic drift." For some historical context, the Drs. Vega and Sherbuk review the 1918 outbreak of the "Spanish Flu" in Philadelphia related to a War Bonds parade. And they then move on to discuss the impact of RSV in both babies and adults during the fall respiratory virus season. Fortunately, an RSV vaccine is available. Also covered are non-pharmacologic interventions to avoid the spread of respiratory infections, such as mask wearing, handwashing, and isolating yourself if you are sick. Lastly, the show closes with some recent ID news about Pertussis (Whooping cough), continuing Listeria outbreaks from meat products, and the McDonalds Quarter Pounder outbreak related to slivered onions. Dr. Vega would like to give a special thank you to her good friend Mr Job Meiller for his musical contributions for our podcast. Thanks also to Dr. Ana Velez, our artistic contributor, for her painting used in our episode thumbnail.
On episode #66 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 10/8 – 10/23/24. Host: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Prevalence of Human Papillomavirus (HPV) and HPV Type Distribution in Penile Samples in Young Men in Denmark: Results 10 Years After Implementation of a Girls-Only HPV Vaccination Program (JID) Primary Care Guidance for Providers of Care for Persons With Human Immunodeficiency Virus: 2024 Update by the HIV Medicine Association of the Infectious Diseases Society of America (CID) Bacterial Adjunctive linezolid versus clindamycin for toxin inhibition in β-lactam-treated patients with invasive group A streptococcal infections in 195 US hospitals from 2016 to 2021: a retrospective cohort study with target trial emulation (LANCET: Infectious Diseases) Time to turn off the toxins: adjuvant suppression of group A streptococcus (LANCET: Infectious Diseases) Comparing rates of recurrent infection for first occurrence of Clostridioides difficile between tapered oral vancomycin and standard vancomycin: a retrospective, propensity matched cohort study(Infection Control and Hospital Epidemiology) Evaluation of primary oral vancomycin prophylaxis against C. difficile infection during autologous stem cell transplantation (OFID) Oral Vancomycin to Prevent C. difficile in Stem Cell Transplant Recipients: The last frontier in antimicrobial prophylaxis (OFID) First Report of a Fatal Septicemia Case Caused by Vibrio metoecus: A Comprehensive Functional and Genomic Study (JID) Fungal The Last of US Season 2 (YouTube) A global chromoblastomycosis strategy and development of the global chromoblastomycosis working group(PLoS Neglected Tropical Diseases) Epidemiological and clinical features of a large blastomycosis outbreak at a paper mill in Michigan (CID) Do morphogenetic switching and intraspecies variation enhance virulence of Candida auris? (PLoS Pathogens) Parasitic Beyond Human Babesiosis: Prevalence and Association of Babesia Coinfection with Mortality in the United States, 2015–2022: A Retrospective Cohort Study (OFID) New WHO guidelines for treating rhodesiense human African trypanosomiasis: expanded indications for fexinidazole and pentamidine (LANCET: Infectious Diseases) Miscellaneous Social and Environmental Benefitsof Pediatric Infectious Disease Telemedicine (Journal of the Pediatric Infectious Diseases Society) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.
Understanding Cholera Vaccine: Essential Information To Take Prevent Deadly Disease Cholera na acute diarrhea infection wen go affect person if dem eat food or water wen dey contaminated with Vibrio cholerae. To know say na em the person go get sudden a
Andrew and Lee talk with Christine and Cynney about the Haiti cholera outbreak Cynney Walters: https://www.linkedin.com/in/cynney-walters-763111190 Walters et al, "Genome sequences from a reemergence of Vibrio cholerae in Haiti, 2022 reveal relatedness to previously circulating strains" https://journals.asm.org/doi/abs/10.1128/jcm.00142-23
Dr. Don and Professor Ben talk about the risks from eating fish in the Olympic Village. Dr. Don - not risky
Dr. Don and Professor Ben talk about the risks from eating escovitch that has been held at room temperature for 12 hours. Dr. Don - risky ☣️ Professor Ben - not risky
Lietuvoje pirmą kartą surengta jūrinė stovykla nuo pajūrio nutolusių regionų moksleiviams, kurios tikslas – populiarinti jūrines profesijas bei didinti jų prestižą ir supažindinti moksleivius su jūrine bendruomene, jos gyvenimu.Šylantis klimatas sudaro tinkamas sąlygas pavojingoms bakterijoms Baltijos jūros pakrantėse plisti. Viena jų – Vibrio bakterija. Europoje atliekamo monitoringo duomenimis, užsikrėtimo rizika yra ir Baltijos jūros regione, o ypač - karštais vasaros mėnesiais, kai jūros vandens temperatūra yra apie dvidešimt laipsnių. Kokia tai liga bei kokių prevencinių priemonių reikėtų imtis atostogaujantiems prie Baltijos jūros poilsiautojams?Dažna ugdymo įstaiga, siekdama visuomenei pristatyti savo veiklą, turi susikūrusi paskyras socialiniuose tinkluose, o mokytojai – dar ir atskiras grupes, pokalbių kanalus, kur greitai ir patogiai komunikuoja su mokiniais ir jų tėvais. Neretai šitaip socialiniuose tinkluose atsiduria ir nuotraukos, kuriose užfiksuota, ką vaikai veikia grupėje ar klasėje, ką patyrė edukacijų, ekskursijų, įvairių švenčių metu. Ar toks vaikų nuotraukų publikavimas visuomet yra teisėtas?Vasarą dažnai galime išgirsti apie karščio bangų varginamus pietų ir vidurio Europos gyventojus. Karščio bangų pasitaiko ir Lietuvoje. Vien šią vasarą kaitrų metu oro temperatūra dažnai viršijo 30 laipsnių. Klaipėdos universiteto Jūros tyrimų instituto mokslininkė-okeanografė Toma Dabulevičienė sako, kad vienas iš klimato kaitos padarinių yra vis dažniau pasitaikančios karščio bangos ne tik sausumoje, bet ir vandens telkiniuose. Tarp jų ir Baltijos jūroje. O tokie reiškiniai sukelia daug neigiamų pasekmių.Ved. Paulius Selezniovas
Today, Dr. Margaret McFall-Ngai of the California Institute of Technology, joins the #QualityQuorum to discuss her philosophy of the future of biology. Dr. McFall-Ngai has been described as “…a recognized thought leader regarding the cornerstone role microbiology plays in the life sciences.” I could not agree more. Host: Mark O. Martin Guest: Margaret McFall-Ngai Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode For beginning #Micronauts, I suggest this overview of the amazing roles microbes play in the lives of animals and plants: “We are living in a bacterial world, and it's impacting us more than previously thought“. Here is the more advanced article coauthored by Dr.McFall-Ngai on this topic: “Animals in a Bacterial World.” A must read. A video on this topic by Dr. McFall-Ngai. Another video on this topic by Dr. McFall-Ngai. A wonderful review of the squid-Vibrio symbiosis (relevant to discussion) from the laboratory of Dr. Karen Visick. The TCT story: how the same signal creates a light organ in squid and disease in humans. PAMPs versus MAMPs as a paradigm shift. A wonderful profile on Dr. McFall-Ngai An essay about career building by Dr. McFall-Ngai. Margaret McFall-Ngai's faculty website. The McFall-Ngai laboratory website. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com
It sounds like the premise of a creepy movie, but this one is real. It is Vibrio vulnificus. It is found in warm salty water where people like to swim. It enters the skin through small cuts and can cause necrotizing fasciitis. Listen and learn about this growing threat.
In this episode Doug talks about the good job of the electrical workers who helped with restoring power after the hurricane Houston endoured. Doug talked about the types of baits used for catching redfish. What are the signs of and what is Vibria bacteria? Doug and some of the callers chime in on what can possibly help you are someone if they get this bacteria. Its coming up, that's right, Its the texas Trophy Hunters Extravaganza. Get all the information you need to enter and win. Golf updates, weather, and tons of tips, along with good o'l fashion fun in this episode with Doug Pike.
Today, Dr. Mark Mandel, Professor of Medical Microbiology & Immunology at University of Wisconsin-Madison, joins the #QualityQuorum to discuss the research his laboratory group does exploring how the luminous bacterium Vibrio fischeri finds its way into its symbiotic partner, the Hawai'ian Bobtail squid Euprymna scolopes. It will be an enlightening podcast! Host: Mark O. Martin Guest: Mark Mandel Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode A video for introductory #Micronauts about the squid-Vibrio symbiosis featuring science journalist Ed Yong and two founders of the field, Dr. Ned Ruby and Dr. Margaret McFall-Ngai. An engaging video about Euprymna scolopes, the larger partner in this symbiosis, described by Dr. McFall-Ngai. A more advanced overview to this field, authored by Dr. Ned Ruby, Dr. Eric Stabb, and Dr. Karen Visick. A very complete recent review of the field from Dr. Visick's lab. A video presentation by Dr. Mandel about this symbiosis. The first paper discussed by Dr. Mandel: “Hybrid Histidine Kinase BinK Represses Vibrio fischeri Biofilm Signaling at Multiple Developmental Stages.” The second paper discussed by Dr. Mandel: “High Levels of Cyclic Diguanylate Interfere with Beneficial Bacterial Colonization.” The third paper discussed by Dr. Mandel: “Mobile-CRISPRi as a powerful tool for modulating Vibrio gene expression.” Dr. Mandel's faculty website. Dr. Mandel's laboratory website Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com
Today, Dr. Nkrumah Grant, Assistant Professor of Microbiology at the University of Illinois at Urbana-Champaign, joins the Quality Quorum today to discuss aspects of his work in bacterial evolution, the challenges of setting up a new research laboratory, and his quite inspiring journey in academia. Host: Mark O. Martin Guest: Nkrumah Grant Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode The long term evolution LTEE program by Rich Lenski and his colleagues, studying bacterial evolution in E. coli. Rich Lenski's website. An enjoyable video about this program. A wonderful explainer of the LTEE program for beginning Micronauts. Cholera as a disease. Vibrio cholera the bacterium. Mechanisms of the cholera toxin. An article about Vibrio cholera, chitin, and natural transformation. Rita Colwell, and her research showing how filtering through sari cloth could reduce the incidence of cholera. Here is an overview for new Micronauts. Chris Waters' laboratory website at Michigan State University. An overview from the American Society for Microbiology, suggesting that many food items are in fact antimicrobial. A review article on the topic of antimicrobial components of food. A preprint of Dr. Grant's research that was discussed during the podcast. An inspirational video of Dr. Grant's path through science. Another video about Dr. Grant's life. An article about Dr. Grant's story. An article by Dr. Grant's institution, welcoming him to Urbana, Illinois. Dr. Grant's faculty page at the University of Illinois at Urbana-Champaign. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com
In our inaugural episode, show hosts Drs. Vivian Vega and Jackie Sherbuk discuss the upcoming Summer travel season and important infections spread by contact with water. Vibrio vulnificus is a potentially deadly illness spreading in the U.S. due to climate change that peaks in the hottest summer months. Vivian discusses risk factors for exposure and how vulnerable individuals can stay safe. Next, Jackie shares three limericks tied to specific waterborne infections, and Vivian has to guess the infectious agent tied to hot tubs, aerosolized water, and other recreational aquatic exposures. Next, the duo discuss Leptospirosis, an important zoonoses (human disease acquired from wild animals) associated with adventurous travel. To close the episode, two Infectious Diseases specialists and travel enthusiasts from the USF's Division of Infectious Diseases, Dr. Shylah Moore-Pardo and Dr. Shivan Shah, discuss how they stay safe during their travel adventures. Dr. Vega would like to give a special thank you to her good friend Dr. Rey Rivera and to Mr Job Meiller for their musical contributions for our podcast.
A different source of global warming, signs of a continentwide tradition of human sacrifice, and a virus that attacks the cholera bacteria First up on the show this week, clearer skies might be accelerating global warming. Staff Writer Paul Voosen joins host Sarah Crespi to discuss how as air pollution is cleaned up, climate models need to consider the decrease in the planet's reflectivity. Less reflectivity means Earth is absorbing more energy from the Sun and increased temps. Also from the news team this week, we hear about how bones from across Europe suggest recurring Stone Age ritual killings. Contributing Correspondent Andrew Curry talks about how a method of murder used by the Italian Mafia today may have been used in sacrifices by early farmers, from Poland to the Iberian Peninsula. Finally, Eric Nelson, an associate professor at the University of Florida's Emerging Pathogens Institute, joins Sarah to talk about an infectious bacteria that's fighting on two fronts. The bacterium that causes cholera—Vibrio cholerae—can be killed off with antibiotics but at the same time, it is hunted by a phage virus living inside the human gut. In a paper published in Science, Nelson and colleagues describe how we should think about phage as predator and bacteria as prey, in the savanna of our intestines. The ratio of predator to prey turns out to be important for the course of cholera infections. This week's episode was produced with help from Podigy. About the Science Podcast Authors: Sarah Crespi; Paul Voosen; Andrew Curry Episode page: https://www.science.org/doi/10.1126/science.zhgw74e Learn more about your ad choices. Visit megaphone.fm/adchoices
La signalisation récente de deux cas de choléra à La Réunion et à Mayotte rappelle que cette maladie infectieuse au potentiel épidémique notable reste présente dans différentes régions du globe. En Inde et aux Comores, notamment, mais aussi en Afrique, la bactérie Vibrio cholerae se transmet surtout par ingestion d'eau ou d'aliments contaminés. Le choléra affecte chaque année des millions de personnes, entrainant par la même des dizaines de milliers de décès.Le point sur les cas récentsC'est le 18 mars qu'un cas suspect de choléra a été détecté en provenance des Comores, à Mayotte. Deux jours plus tard, un autre cas était signalé à La Réunion. Les agences régionales de santé concernées ont réagi au plus vite, notamment en initiation des mesures de précaution et un contact tracing permettent de retrouver toutes les personnes susceptibles d'avoir été contaminées. L'objectif est clair : circonscrire la propagation de la maladie.Mayotte s'avère particulièrement sensible au choléra à cause de sa proximité avec les Comores, une région endémique où la maladie sévit régulièrement. Elle dispose d'un plan d'action spécifique pour gérer l'apparition de cas sur son territoire, plan qui s'est mis en œuvre et souligne l'importance d'une bonne préparation face à la maladie infectieuse.Explications sur le choléraQu'est-ce que le choléra, exactement ? Cette infection est causée par une bactérie qui se développe dans l'eau ou la nourriture. Vibrio cholerae entraine une diarrhée aqueuse sévère, qui conduit à la déshydratation fatale sans traitement approprié. Les lieux les plus vulnérables sont ceux manquant d'accès à l'eau potable et à des installations d'assainissement adéquates comme les pays les plus pauvres. Les voyages vers des zones endémiques augmentent le risque d'exposition au choléra.Symptômes et diagnosticLe choléra se manifeste par des symptômes parfois légers, car beaucoup de personnes infectées ne s'en rendent pas compte. Mais, dans les cas graves, la maladie cause une diarrhée profuse et aqueuse, avec des vomissements et des crampes musculaires. Les conséquences de cet état sont la déshydratation rapide et le déséquilibre électrolytique. Sans traitement, la maladie peut être fatale en seulement quelques heures.Pour diagnostiquer le choléra, les médecins identifient la bactérie dans les selles du patient. Cette étape est cruciale afin de mettre en place un traitement efficace et des mesures de contrôle pour éviter la propagation de la maladie.VaccinationPlusieurs vaccins protègent du choléra et sont indiqués dans les zones endémiques. Administrés par voie orale, ils stimulent le système immunitaire pour qu'il produise des anticorps contre le Vibrio cholerae. Mais la protection ne dure que 2 à 3 ans. Il faut donc pratiquer des rappels fréquents lorsque l'on vit ou voyage dans les régions où le choléra reste fréquent. Hébergé par Acast. Visitez acast.com/privacy pour plus d'informations.
A different source of global warming, signs of a continentwide tradition of human sacrifice, and a virus that attacks the cholera bacteria First up on the show this week, clearer skies might be accelerating global warming. Staff Writer Paul Voosen joins host Sarah Crespi to discuss how as air pollution is cleaned up, climate models need to consider the decrease in the planet's reflectivity. Less reflectivity means Earth is absorbing more energy from the Sun and increased temps. Also from the news team this week, we hear about how bones from across Europe suggest recurring Stone Age ritual killings. Contributing Correspondent Andrew Curry talks about how a method of murder used by the Italian Mafia today may have been used in sacrifices by early farmers, from Poland to the Iberian Peninsula. Finally, Eric Nelson, an associate professor at the University of Florida's Emerging Pathogens Institute, joins Sarah to talk about an infectious bacteria that's fighting on two fronts. The bacterium that causes cholera—Vibrio cholerae—can be killed off with antibiotics but at the same time, it is hunted by a phage virus living inside the human gut. In a paper published in Science, Nelson and colleagues describe how we should think about phage as predator and bacteria as prey, in the savanna of our intestines. The ratio of predator to prey turns out to be important for the course of cholera infections. This week's episode was produced with help from Podigy. About the Science Podcast Authors: Sarah Crespi; Paul Voosen; Andrew Curry Episode page: https://www.science.org/doi/10.1126/science.zhgw74e Learn more about your ad choices. Visit megaphone.fm/adchoices
Dr. Don and Professor Ben talk about the risks from eating ceviche. Dr. Don - not risky
Today, Associate Professor of Biology Dr. Julia van Kessel of Indiana University will chat with us about how groups of bacteria can sense one another and carry out behavior as a collective…including some kinds of disease! Host: Mark O. Martin Guest: Julia van Kessel Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode An introduction to the horrific disease leprosy, caused by the quite strange organism Mycobacterium leprae. An overview of the Hansen Institute in Ethiopia. A solid overview of quorum sensing. A very interesting review article about quorum sensing. A video that two of my Bio350 Micronauts (including a former guest of our podcast, Dr. Ruth Isenberg) put together some years ago to illustrate the idea of quorum sensing. A very clear overview of quorum sensing by the highly energetic and brilliant Dr. Bonnie Bassler, one of the giants of this field. A #LuxArt show I organized a few years ago at Carleton College, where I encouraged students to create art by “painting” with luminous bacteria on Petri dishes. It is a true merger of art and science. Using Chromobacterium to “look” for quorum sensing molecules. I made this imperfect video to illustrate the concept. My old friend Vibrio harveyi, which Dr. van Kessel uses in her laboratory. Vibrio coralliilyticus, which causes coral diseases. If you are interested in learning about how some bacteria have what seems to be a molecular switchblade knife—the Type 6 Secretory System— to use against other bacteria or other organisms, the link above is a fine place to start. In addition, a Bio350 student of mine made a lovely Claymation video of the process some years ago. Here is Dr. van Kessel's faculty website at Indiana University in Bloomington. Here is the laboratory website—with excellent graphics and videos—of Dr. van Kessel's group. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com
In this episode, we review the high-yield topic of Vibrio parahaemolyticus / vulnificus from the Microbiology section. Follow Medbullets on social media: Facebook: www.facebook.com/medbullets Instagram: www.instagram.com/medbulletsofficial Twitter: www.twitter.com/medbull --- Send in a voice message: https://podcasters.spotify.com/pod/show/medbulletsstep1/message
Dr. J. Glenn Morris, the director of the Emerging Pathogens Institute at the University of Florida, and Sarah Gregory discuss the origin and spread of cholera in Haiti.
Today Dr. Ruth Isenberg, postdoctoral scholar (and former #DocMartian!) in the Willett Lab at the University of Minnesota, will tell us about her first generation path in science, the squid-Vibrio symbiosis work she did for her PhD, and her current career path. Host: Mark O. Martin Guest: Ruth Isenberg Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode The Sikhote-Alin meteorite fall. An article on Kenyan Sand Boas. An article on African Fire Skinks. A video reminder about ice nucleation bacteria. An article relating snowflakes to ice nucleation bacteria A reminder of the nature of bacterial colonies. The laboratory website of Dr. Kat Milligan-McClellan. The laboratory website of Dr. Mark Mandel. The laboratory website of Dr. Julia Willett. A great place to begin thinking about the squid-Vibrio symbiosis, as well as the microbiome in general. An excellent review article on the squid-Vibrio symbiosis. A fun and accessible video from the famed science journalist Ed Yong about the squid-Vibrio symbiosis. An article written by Ruth about her work on this symbiosis Ruth's excellent claymation video made for my microbiology class about quorum sensing and the squid-Vibrio symbiosis. Student creativity matters! Another #Micronaut's claymation video about Type VI secretory systems. Student creativity matters! Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com
In this episode, it's Necrogamy and Flesh-Eating Bacteria! Join us as we explore two bizarre and unsettling topics that are both intriguing and horrifying. First, we venture into the obscure world of Necrogamy, a macabre practice that defies conventional norms. Discover the shocking details of the laws in France that permit unions between the living and the deceased. Is it love beyond the grave or just a morbid curiosity? Tune in as we unravel the haunting truths behind this peculiar phenomenon. Then, we'll explore the terrifying realm of Vibrio vulnificus, a deadly bacterium that thrives in the murky waters of our planet. Learn about the gruesome consequences of a Vibrio vulnificus infection, including the dreaded flesh-eating bacteria. The stories we share will send shivers down your spine, making you think twice about eating raw shellfish or taking that next swim in the ocean. The Box of Oddities, where we explore the darkest corners of human curiosity and nature's most horrifying surprises. Subscribe now and prepare for a rollercoaster of the bizarre and the unsettling!
In this episode, it's Necrogamy and Flesh-Eating Bacteria! Join us as we explore two bizarre and unsettling topics that are both intriguing and horrifying. First, we venture into the obscure world of Necrogamy, a macabre practice that defies conventional norms. Discover the shocking details of the laws in France that permit unions between the living and the deceased. Is it love beyond the grave or just a morbid curiosity? Tune in as we unravel the haunting truths behind this peculiar phenomenon. Then, we'll explore the terrifying realm of Vibrio vulnificus, a deadly bacterium that thrives in the murky waters of our planet. Learn about the gruesome consequences of a Vibrio vulnificus infection, including the dreaded flesh-eating bacteria. The stories we share will send shivers down your spine, making you think twice about eating raw shellfish or taking that next swim in the ocean. The Box of Oddities, where we explore the darkest corners of human curiosity and nature's most horrifying surprises. Subscribe now and prepare for a rollercoaster of the bizarre and the unsettling! Learn more about your ad choices. Visit megaphone.fm/adchoices
In this episode, we review the high-yield topic of Vibrio cholerae from the Microbiology section. Follow Medbullets on social media: Facebook: www.facebook.com/medbullets Instagram: www.instagram.com/medbulletsofficial Twitter: www.twitter.com/medbullets --- Send in a voice message: https://podcasters.spotify.com/pod/show/medbulletsstep1/message
The doctors discuss the passing of Jimmy Buffett and the details of his skin cancer Merkel cell carcinoma. Vibrio vulnificus and "flesh-eating bacteria" from the ocean, what this is, and who might be at risk. And the fall of the Biotech firm Amyris and what might happen to beloved brands like Biossance. 1:25 - Dr. Shah's trip to Japan. 3:54 - Jimmy Buffett and Merkel cell carcinoma 13:36 - Trending topic - Flesh Eating Bacteria 20:21 - The Biz of Beauty - Amyris files for bankruptcy Disclaimer: This podcast is not intended to provide diagnosis, treatment, or medical advice. Content provided in this podcast is for educational purposes only. Please consult with a physician regarding any health-related diagnosis or treatment.
The Vibrio vulnificus pathogen thrives in hot coastal waters, and beachgoers can contract it via a small cut or scrape. It can also kill them in two days. Read this story here. Learn more about your ad choices. Visit megaphone.fm/adchoices
COVID cases continue to rise in the U.S. due to the new EG.5, or Eris, variant. AMA's Vice President of Science, Medicine and Public Health, Andrea Garcia, JD, MPH, analyzes the increase in COVID hospitalizations and shares the latest news about the EG.5 and BA.2.86, or Pirola, variants. Plus, the CDC Health Advisory on fatal Vibrio vulnificus (or V. vulnificus) infections and what physicians and patients need to know about it. American Medical Association CXO Todd Unger hosts.
Tucker Carlson has claimed Barack Obama was smoking crack and having sex with men, but the media failed to report it ahead of the 2008 presidential election. Tensions are rising between President Biden and blue state Democrats trying to stem the tide of migrants flowing from Republican border states. The CDC is warning doctors to be on the lookout for deadly flesh-eating bacteria known as Vibrio vulnificus or V. vulnificus that may be in waters of the Gulf of Mexico and East Coast. Tuesday - 9/5/2023 - Hour 1See omnystudio.com/listener for privacy information.
Recent hurricanes on the West and East coast have threatened millions, and it's important for you to know what to do if one of these juggernauts is heading in your direction. Dr. Joe Alton tell you what you need to know. Last time, we talked about shark attacks, but many more people are injured by less scary critters like sting rays and jellyfish. Dr. Alton tells you what to do for these injuries, and also talks about the recent spate of cases of marine waters that harbor Vibrio vulnificus, the flesh eating bacteria that has killed several people this summer. Plus, heavy rains from Cyclone Hilary have cause flash floods and mudslides in the normally desert Southwest. Dr. Bones tells you all about them, and what to do before you build that dream retreat in the mountains, how to harden a home already built, and what to do if the river of mud is an imminent threat. All this and more on the Survival Medicine Podcast with Joe and Amy Alton, aka Dr. Bones and Nurse Amy! Wishing you the best of health in good times or bad, Joe and Amy Alton Hey, don't forget to check out our entire line of quality medical kits (including suture kits) at store.doomandbloom.net. Also, our Book Excellence Award-winning 700-page SURVIVAL MEDICINE HANDBOOK: THE ESSENTIAL GUIDE FOR WHEN HELP IS NOT ON THE WAY is now available in black and white on Amazon and in color and color spiral-bound versions at store.doomandbloom.net.
Dr. Evelyn Huang, a doctor in Emergency Medicine at Northwestern Memorial Hospital, joins Lisa Dent to explain what we should know about the rare flesh-eating bacteria that has been found in raw shellfish and what we should be on the lookout for. “Better knowledge means better health for you and your family. Turn to Northwestern Medicine at […]
There have now been two confirmed deaths in Connecticut and another in New York linked to Vibrio bacteria in the water. Vibrio has not been detected in Connecticut waters or from raw shellfish consumed by residents, but we're seeing an uptick in cases. Dr. Browne explains why the warmer waters play a huge role in that. We also talked about the incredibly rare brain-eating amoeba and West-Nile virus detected in CT mosquitoes. IMAGE CREDIT: iStock / Getty Images Plus
California's home insurance crisis gets worse amid rising climate threats The current risk assessment models in the insurance industry are no longer tenable in the face of the climate crisis. Two major insurers, State Farm and Allstate, have halted new homeowners' policies in California. And, you guessed it, it's because of prevailing climate change-related disasters like fires and mudslides that make payouts to policyholders unsustainable for these insurance companies. It's part of the trickle-down effect of increased climate-driven disasters. In California, regulatory measures that prevent insurers from raising rates have created a dilemma. While such constraints help maintain affordable costs for homeowners, they make it difficult for insurers to cover policy costs and handle increased payouts. The scenario has culminated in more considerable insurance market risks, which must accurately reflect the true extent of climate change-induced disasters. The implications for the insurance industry are far-reaching—it will have to raise rates, risk upsetting homeowners, or potentially go out of business if regulations prevent rate increases. Furthermore, the possibility of homes becoming uninsurable can affect potential homeowners' ability to get a mortgage. In short: Insurance companies must adapt their pricing and risk evaluation methods to account for climate change's increased and unpredictable risks. The ripple effects of the Great Atlantic Sargassum Belt Human activities have caused an unprecedented explosion of seaweed growth, notably Sargassum seaweed, in the Atlantic Ocean. It has created what's known as the Great Atlantic Sargassum Belt and poses unforeseen and potentially significant impacts. The Great Atlantic Sargassum Belt originates from nutrient-dense agricultural runoff and deforestation debris carried into the Atlantic by the Amazon River floods. It stretches from the west coast of Sierra Leone, across the Atlantic, through the Caribbean, and into the Gulf of Mexico. Sargassum emits hydrogen sulfide, which smells foul and can cause eye, throat, and skin irritation. That means the excessive Sargassum growth washing up on shires will continue to affect tourism. Caribbean and coastal Florida economies will need more time and money to remove seaweed from beaches. Worse yet, the Sargassum seaweed has become a plastic trap, making it more likely that wildlife will ingest more plastic. The plastic tangled in the seaweed also attracts a kind of bacteria called Vibrio, which can pose health risks to humans and marine life. The proliferation of Sargassum also poses an existential threat to coral reefs, physically smothering the reefs from light and oxygen. In extreme cases, large patches of Sargassum can choke desalinization plants, which happened in St. Croix and led to an 18-day state of emergency.
En este episodio hablaremos de lo mágico y sorprendente de la bioluminiscencia, el proceso por el cual algunos seres vivos producen su propia luz. Platicamos de químicamente qué pasa para que esto sea posible, y para qué les sirve a las especies. Habrá además una aparición sorpresa de Cristóbal Colón, y cómo unos gusanos bioluminiscentes tal vez le mostraron el camino hacia América. Además vamos a hablar sobre la relación simbiótica que existe entre unos calamares y la bacteria Vibrio fischeri, que hace que el calamar pueda tener su propia luz, pero sobre todo nos muestra cómo el desarrollo de órganos animales puede depender de las relaciones simbióticas que tengan. En el pilón para Patreons vamos a hablar de los beneficios que nos ha dado la bioluminiscencia a los seres humanos, donde el mundo de la medicina le ha dado diversos usos a esta reacción química. Learn more about your ad choices. Visit megaphone.fm/adchoices
Dr. Don and Professor Ben talk about the risks of Reusing Bamboo Chopsticks hand washed with soap and water for raw sushi. Dr. Don - not risky
Warming temperatures create ideal conditions for potentially fatal Vibrio vulnificus infections to spread.
Salty talks: Conversations on Sustainable Aquaculture in Maine
Atlantic Salmon and Maine's renewable wood pulp industry may sound like an unlikely duo at first, but Deborah Bouchard and Sarah Turner from the Aquaculture Research Institute (ARI) have recognized the potential this pairing could have for the future of environmental, economic, and social sustainability for the US aquaculture industry. Debbie and Sarah Bouchard are to researching a new generation of safer, more sustainable, and cheaper vaccines for finfish. Here is where Atlantic Salmon meets its unlikely match, wood pulp. This abundant polymer is biocompatible, biodegradable, quite versatile, and easily modified – making it a phenomenal candidate for drug delivery. Tune in to learn more and hear about their results so far! and Vibrio ordalii. This adjuvant, a component of vaccines to improve and prolong immuneresponse, showed no evidence of cellular damage and no effects on growth for the fish whileinducing a strong immune and antibody boosting response. With less side effects and cheaper tomanufacture than existing vaccines these preliminary results are exciting, highlighting the efficacyof nanocellulose adjuvants. ISAv and V. ordalii alone can cause farmers to lose 90% of their stocks, amounting to over $1billion annually. Development of this new, safe, and affordable vaccine using nanocellulose is notonly huge for Atlantic salmon farmers but other food production systems as well. This newgeneration of low cost, tunable vaccine formulation is paving a way toward more sustainableaquaculture, with potential applicability for other fish species and even terrestrial animals as well. Leveraging direct industry support from Cooke Aquaculture, Kennebec River Biosciences,Benchmark Animal Health LTD, this interdisciplinary team from UMaine's Aquaculture ResearchInstitute and the Chemical and Biomedical Engineering Department has immense experience andresources relating to fish health, immunobiology, and vaccine formulation. Results will be shareddirectly through ARI's web site, Cooperative Extension and Maine Sea Grant extensionprofessionals, national conferences, and peer-reviewed publications.
3.20 Vibrio Species Microbiology review for the USMLE Step 1 Exam Vibrio species are gram negative comma-shaped rods with a single flagellum, allowing them to move quickly Two main species that cause human infections: Vibrio cholerae and Vibrio vulnificus Vibrio cholerae causes foodborne disease called cholera through cholera toxin secretion, spread through the fecal-oral route in developing countries Cholera is characterized by watery, mucinous diarrhea, if left untreated can lead to hypovolemic shock and high mortality Treatment involves rapid rehydration and electrolyte replacement, antibiotics may be used for severe cases Vibrio vulnificus causes severe skin infections acquired through exposure of open wounds in marine environments Symptoms include cellulitis, swelling, blister formation, ulceration, and hemorrhagic bullae
3.04 Gram Negative Bacteria Microbiology review for the USMLE Step 1 Exam. Gram negative bacteria are characterized by a thin cell wall surrounded by a lipid outer membrane They do not retain the violet gram stain and appear pink after staining Gram negative bacteria can be classified by shape: cocci, coccobacilli, bacilli, and spirals Gram negative cocci include Neisseria species, which can be further categorized as maltose fermenters or non maltose fermenters Gram negative coccobacilli include: Bordetella pertussis, Haemophilus influenzae, Pasteurella, Francisella tularensis, Brucella, and Acinetobacter Gram negative bacilli can be divided into lactose fermenting and non lactose fermenting categories Lactose fermenting gram negative bacilli include: Escherichia coli, Klebsiella, Enterobacter, Citrobacter, and Serratia Non lactose fermenting gram negative bacilli can be further divided into oxidase positive and oxidase negative Oxidase positive non lactose fermenting gram negative bacilli include Pseudomonas Oxidase negative non lactose fermenting gram negative bacilli include Shigella, Yersinia, and Salmonella Gram negative spirals can be divided into oxidase positive and oxidase negative categories Oxidase positive gram negative spirals include Vibrio species, Helicobacter pylori, and Campylobacter jejuni Oxidase negative gram negative spirals include Borrelia burgdorferi (cause of lyme disease) and Treponema pallidum (cause of syphilis)
The Intuitive Customer - Improve Your Customer Experience To Gain Growth
A lot of the behavioral sciences can feel intimidating. However, it doesn't have to be. The Five Rules Podcast Series is our attempt at giving you an easy entry point into the complex and messy world of Behavioral Science. As if the world isn't crazy enough—with the war in Ukraine, the cost-of-living crisis, the looming threat of recession, and the ostensible beginnings of catastrophic climate change— we learned a flesh-eating bacterium (Vibrio vulnificus) is running rampant in Florida, infecting people as it thrives in the brackish floodwaters left in the wake of Hurricane Ian. It's bloody stressful these days. With so many things we can't control, feeling uncertain about the future economy is normal. However, uncertainty is a difficult environment in which to move forward with business. Colin thought maybe he was feeling so pessimistic about everything because he is getting old. So, he polled his followers on LinkedIn a few days ago to see what they thought. He asked them,"What are you expecting the business environment will be over the next year?" The results might surprise you. However, no matter how we all feel about the future, into it we go anyway. So, in an effort to help us all cope with the road ahead, we present the 5 Rules for Managing Uncertainty in this episode, which you can also watch on our YouTube Channel. Key Ideas to Improve your Customer Experience Uncertainty is a difficult environment for decision making. Often, we look for ways to mitigate these feelings using short-cuts in decision making to move forward. It's also why we like to say a decision was a no-brainer. If the best way forward was so obvious that we didn't have to think about it much, we have much more certainty about it. Certainty is definitely our preferred state when we decide things. Here are a few key moments in the discussion: 01:49 We start off by explaining the situation behind the poll and what Colin and Ryan think about the future. Spoiler alert: they don't agree. 05:35 We share some participant insights, first from René Bomholt and then from Andrew Safnauer, who tell us that it will be different in various parts of the world and that thinking about having a recession is the surest way to ensure there is one. 08:57 We share the first rule, to recognize that uncertainty will happen, and it will be uncomfortable. 15:07 We talk about the positives of uncertainty in rule number two, which is to remember that the upside of uncertainty is it provide opportunity, especially to disrupt things. 17:57 Colin shares why he likes to wear his Luton Town Football Club shirt—even though the team isn't as good as he wishes it was—and how an ex-manager was the inspiration for Rule #3, control the controllables. 22:27 We get into Rule #4, which is to be alert and prepared; because being flat footed and unprepared is never a winning response to uncertainty while having more information and a plan is. 24:25 We explain why the last rule, hoping for the best while planning for the worst, is an excellent way to cope with uncertainty, and why it can pay off for you no matter which way things go. Please tell us how we are doing! Complete this short survey. Customer Experience Information & Resources LinkedIn recognizes Colin Shaw as one of the 'World's Top 150 Business Influencers.' As a result, he has 290,000 followers of his work. Shaw is Founder and CEO of Beyond Philosophy LLC, which helps organizations unlock growth by discovering customers' hidden, unmet needs that drive value ($). The Financial Times selected Beyond Philosophy as one of the best management consultancies for the last four years in a row. Follow Colin on LinkedIn and Twitter. Click here to learn more about Professor Ryan Hamilton of Emory University. Why Customers Buy: As an official "Influencer" on LinkedIn, Colin writes a regular newsletter on all things Customer Experience. Click here to join the other 35,000 subscribers. How can we help? Click here to learn more about Beyond Philosophy's Suite of Services.
Vibrios are marine bacteria that live in aquatic environments with a lot of other microbes, and occasionally a particular strain will arise that can cause serious disease in humans and can spread through the population in pandemics. V. cholerae causes large pandemics of cholera, and V. vulnificus causes sporadic cases of necrotizing fasciitis. Genomic sequencing has allowed scientists to follow the evolution of pathogens as they pass through the human population, and highlighted specific genomic changes that are associated with disease. Dr. Salvador Almagro-Moreno is an assistant professor in the Burnett School of Biomedical Sciences at the University of Central Florida. Dr. Almagro-Moreno is studying how pathogens emerge from a background of relatively harmless environmental organisms. Dr. Almagro-Moreno discusses how Vibrios can arise that cause disease, how the environment can influence pathogenic traits that are advantageous inside of a host, how oysters may be a training ground for Vibrio vulnificus pathogenesis in humans, how growing up on an island in Spain sparked his interest in marine pathogens, how climate change has impacted Vibrio-related disease, and how playing flamenco guitar keeps him sane. The microCase for listeners to solve is about France Holiday, an anti-vax social media influencer who gets more than she bargained for while promoting an antibacterial drinking straw. Participants: Karl Klose, Ph.D. (UTSA) Salvador Almagro-Moreno, Ph.D. (University of Central Florida) Mylea Echazarreta (UTSA) Cameron Lloyd (UTSA)
Dr. John Mekalanos (Harvard Medical School) has devoted his career to the study of bacterial pathogens, with a special emphasis to understanding Vibrio cholerae, the bacterium that causes the deadly disease cholera. And what an amazingly productive research path he has followed, from the discovery and characterization of the regulon that controls V. cholerae virulence, to the identification of the pilus that allows the bacteria to colonize the intestine, to the discovery of the bacteriophage that encodes the cholera toxin. His (relatively) recent discovery of the Type VI Secretion System and characterization of its role in inter-bacterial competition and host modulation has had broad impact on all aspects of microbiology. Dr. Mekalanos received the 2022 ASM Lifetime Achievement Award for all of his tremendous contributions to our understanding of bacterial-host interactions. Dr. Mekalanos talks about the background of some of the seminal discoveries from his laboratory, how important his laboratory personnel (graduate students, postdoctoral fellows) have been to his success, his thoughts on the eradication of cholera through vaccination, and how his love of poker has contributed to his success as a scientist. Participants: Karl Klose, Ph.D. (UTSA) John Mekalanos, Ph.D. (Harvard Medical School) Karla Satchell, Ph.D. (Northwestern University)
Join our Emergency General Surgery team as they discuss Necrotizing Soft-Tissue Infections. Hosted by Drs. Jordan Nantais, Ashlie Nadler, Stephanie Mason and Graham Skelhorne-Gross. Necrotizing Soft-Tissue Infections: - Also known as “flesh eating disease”, gas gangrene, necrotizing fasciitis/myositis, Fournier's gangrene. - Early findings are non-specific - Rapidly fatal - diagnostic delay can lead to tremendous additional morbidity and mortality Classification: - Type 1 - polymicrobial category (most common) found in immunosuppressed or elderly - Type 2 - monomicrobial infection [Group A Streptococcus > Methicillin-resistant Staphylococcus aureus (MRSA)] - Type 3 - monomicrobial infection (Vibrio or Clostridium) - Type 4 - fungal (rare) in immunocompromised or after penetration or trauma from candida or Zygomycetes. Initial Workup - History: (comorbidities, immunosuppression, recent infections or trauma) - Exam: swelling, open lesions, drainage, erythema, crepitus, and pain out of proportion - Most common: swelling, pain, erythema - Bullae, skin necrosis, crepitus are less common - Labs: Hb, wbc, Na, Creat, glucose, and CRP - Imaging: CT, MRI *sensitive and specific but may not change management - Cut-down: bedside vs in OR - Gm stain Management - Initially: two large bore IVs, foley catheter, aggressive fluid resuscitation, broad spectrum antibiotics, vasopressors PRN - Abx choices: carbopenem or piperacllin-tazobactam or cefotaxime plus metronidazole. Clindamycin (antitoxin effect) and vancomycin (MRSA) should be considered. - OR: must debride all dead/infected tissue, involve other surgical specialties as needed - Mark edge of cellulitis and use as initial debridement - Healthy dermis – pearly and white - Healthy fat – pale, yellow, glistening - Healthy fascia – should bleed, doesn't easily separate from muscle - Healthy muscle – contract with cautery - Dressing: betadine-soaked gauze on the wound - Most patients will need at least 3 ORs (second OR generally 8-12 hours after the first) - No VAC or stoma at first OR References: 1. Pelletier J, Gottlieb M, Long B, Perkins JC Jr. Necrotizing Soft Tissue Infections (NSTI): Pearls and Pitfalls for the Emergency Clinician. J Emerg Med. 2022 Apr;62(4):480-491. doi: 10.1016/j.jemermed.2021.12.012. Epub 2022 Jan 31. 2. Sarani B, Strong M, Pascual J, Schwab CW. Necrotizing fasciitis: current concepts and review of the literature. J Am Coll Surg. 2009 Feb;208(2):279-88. 3. Edlich RF, Cross CL, Dahlstrom JJ, Long WB 3rd. Modern concepts of the diagnosis and treatment of necrotizing fasciitis. J Emerg Med. 2010 Aug;39(2):261-5 4. Hoesl V, Kempa S, Prantl L, Ochsenbauer K, Hoesl J, Kehrer A, Bosselmann T. The LRINEC Score-An Indicator for the Course and Prognosis of Necrotizing Fasciitis? J Clin Med. 2022 Jun 22;11(13):3583 5. Bulger EM, May A, Bernard A, Cohn S, Evans DC, Henry S, Quick J, Kobayashi L, Foster K, Duane TM, Sawyer RG, Kellum JA, Maung A, Maislin G, Smith DD, Segalovich I, Dankner W, Shirvan A. Impact and Progression of Organ Dysfunction in Patients with Necrotizing Soft Tissue Infections: A Multicenter Study. Surg Infect (Larchmt). 2015 Dec;16(6):694-701. 6. LRINEC Score from: https://www.mdcalc.com/calc/1734/lrinec-score-necrotizing-soft-tissue-infection#:~:text=Patients%20were%20classified%20into%20three,%25%20and%20NPV%20of%2096%25. Retrieved July 2022. If you liked this episode, check out our recent episode titled, "Journal Review in Colorectal Surgery: Timing of Biologics and Surgery in the Setting of Crohn's Disease" which can be found here. Please visit behindtheknife.org to access other high-yield surgical education podcasts, videos and more.
00:46 The very cool experiment looking for a proposed particlePhysics tells us that when matter is created, antimatter should be as well. But while the Universe is full of matter, there's surprisingly little antimatter to be found. To try and understand this imbalance, a team have built a detector kept just above absolute zero which they are using to look for a hypothesised, ultra-rare type of particle decay that could create matter without antimatter.Research article: The CUORE CollaborationNews and Views: Cryogenic mastery aids bid to spot matter creation09:43 Research HighlightsSubsidence of coastal cities makes them more vulnerable to sea-level rise, and tackling ‘crazy ants' with a parasitic fungus.Research Highlight: Global cities are sinking — and humans are partly to blameResearch Highlight: Marauding crazy ants come to grief when a fungus comes to call12:17 Solving the puzzle of the missing plasmidsBacteria are well known for their ability to share genes, which they often do using small circles of DNA called plasmids. But while plasmids are common in bacteria, a long-standing mystery has been why they are absent in a group of cholera-causing strains of Vibrio cholerae. Now, a team might have solved this mystery, by discovering two previously unknown DNA defence systems that eliminate plasmids, hidden in the bacteria's genomes.Research article: Jaskólska et al.News and Views: Bacterial defence systems degrade plasmid invaders18:41 Briefing ChatWe discuss some highlights from the Nature Briefing. This time, what smelling jars from an Egyptian tomb has revealed about ancient burial practices, and the latest report from the IPCC.Science: Ancient smells reveal secrets of Egyptian tombNature: IPCC's starkest message yet: extreme steps needed to avert climate disasterSubscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday. See acast.com/privacy for privacy and opt-out information.