Podcasts about signaling

Twyla Tharp is a world-renowned dancer, choreographer and expert on the creative process. She explains how to achieve creative success by keeping a highly disciplined routine that ultimately allows you to bring your creative visions to life. She explains how to establish a central message for each project, how to think about your audience, navigate criticism and continually elevate your standards with daily actions. We discuss how one's view of hard work, competition and even your name can shape what you think you're capable of and ultimately achieve. This episode offers direct, practical advice from a world-class creator on how to access your inner vision, build a strong body and mind, and do your best work. Show notes: https://go.hubermanlab.com/Yx57rWq Thank you to our sponsors AG1: https://drinkag1.com/huberman Our Place: https://fromourplace.com/huberman Eight Sleep: https://eightsleep.com/huberman LMNT: https://drinklmnt.com/huberman Mateina: https://drinkmateina.com/huberman Timestamps (00:00:00) Twyla Tharp (00:03:28) Focus & Creative Work, Tool: "Spine" of Creative Work (00:06:22) Creator & Audience Dynamic; Intention, Finances (00:11:57) Early vs Late Works, Learning & Selectivity throughout Career (00:15:59) Sponsors: Our Place & Eight Sleep (00:19:09) "Cubby-Holing", Career Change & Reputation (00:21:48) Creator Community & Selectivity; Success & Useful Failure (00:27:42) Work Process, Schedule; Selecting Dancers, Supporting the Arts, Expectations (00:32:36) Successful Performance; Beauty, Arts Compensation (00:36:22) Mikhail Baryshnikov, Ballet & Invention; Philip Glass, Minimalism (00:43:18) Knowledge vs Instinct, Taste; Avant Garde; Classical Training (00:47:05) Kirov Ballet, Kids, Uniformity; Body Types (00:52:13) Sponsor: AG1 (00:53:36) Movement, Body Frequency, Power (01:00:18) Creative Process, Spine; Idea, Habit (01:04:15) Rituals, Gym, Discipline; Farming, Quaker & Community; Communication (01:12:16) Communication, Signaling & Distance; Feeling Emotion (01:18:11) Boxing, Strength Training (01:21:41) Sponsors: LMNT (01:23:01) Ballet Barre Work, Fundamentals (01:29:09) Body's Knowledge, Honoring the Body, Kids & Movement (01:35:42) High Standards & Childhood; Wordlessness & Movement, Twins (01:41:31) Translator, Objectivity; Critics, Creator Honesty (01:46:50) Sponsor: Mateina (01:47:50) Evolution & Learning; Amadeus Film & Research (01:53:53) Medicine, Keto Diet; Ballet Training & Performance, Desire (02:00:50) Young Dancers & Competition, Intrinsic vs Extrinsic Reward, Hard Work (02:08:47) Tool: "The Box"; Ritual, Practice vs Habit; Honorary Degrees (02:13:37) Tool: Idea "Scratching"; Movement & Longevity, Apprentice (02:19:46) Aging & Less Movement, Fearlessness; Taking Up Space, Names (02:25:42) Acknowledgements (02:27:18) Zero-Cost Support, YouTube, Spotify & Apple Follow, Reviews & Feedback, Sponsors, Protocols Book, Social Media, Neural Network Newsletter Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices

In this transformative conversation, Darin sits down with world-renowned regenerative medicine pioneer Dr. Christopher Rogers, a physician with over 25 years of experience, 80,000+ patients treated, and a global reputation for advancing non-surgical orthopedic healing. In this episode, Dr. Rogers breaks down the real science behind PRP, stem cells, cartilage regeneration, tendon repair, and why so many people are told to get unnecessary surgeries. This is a deep dive into the future of healing — and the intelligence already built into your own body.     What You'll Learn 00:00:00 Welcome to SuperLife: exploring sovereignty, healing & possibility 00:00:33 Sponsor: Energy Bits and Whole-Food Algae Nutrition as Dense as a Plate of Vegetables 00:01:51 Introducing Dr. Christopher Rogers: 25 Years, 80,000+ Patients, Regenerative Medicine Leader 00:03:28 Darin's Personal Stem Cell Treatment Experience & Early Results 00:04:17 Dr. Rogers' Journey from Sports Medicine to Regenerative Orthopedics 00:05:58 The Moment that Changed Everything: Discovering PRP as an Alternative to Surgery 00:06:45 The Dinner that Changed His Career: Meeting Dr. Arnold Kaplan, Discoverer of Mesenchymal Stem Cells 00:07:13 PRP: What it Actually Is, Why Dose Matters, and How to Use It Effectively 00:10:36 The Wild West of Stem Cell Therapy: Misinformation & The Need for Science 00:13:24 The Core Mechanism: Stem Cells Work by Signaling the Body to Heal 00:16:07 Exosomes, Nanotubes, and the Secret Communication of Stem Cells 00:17:45 Bone Marrow vs. Adipose vs. Culture Expansion: The Critical Dose Problem 00:22:28 Autologous vs. Donor Cells: Why Using Your Own is Safer and More Effective 00:24:51 Sponsor: Fatty15 and the Science of C15 for Mitochondrial & Cellular Health 00:28:32 The Path to Safety: FDA-Approved Trials and the Right to Try Law 00:35:44 The Next Step: Getting Regenerative Therapy Approved as Standard of Care 00:37:08 The Ultimate Excitement: Healing Rotator Cuffs and Alleviating Global Suffering 00:41:07 The Orthopedic Surgeon Who Treated Himself with Stem Cells 00:42:02 Four Rules to Avoid Falling Victim to Stem Cell Hype and Unproven Clinics 00:47:36 Sponsor: SuperLife Patreon 00:49:08 The Frustration of Unregulated Clinics Undercutting Real Science 00:51:36 The Future: What Stem Cell Therapy Will Look Like in 5-10 Years 00:56:25 Systemic Use: The Potential for IV Infusions to Modulate the Immune System 01:01:26 Stem Cells and Cancer: Is There an Increased Risk? (The Data Says No) 01:03:10 Unexpected Healing: A Full ACL Tear Healed with Regenerative Therapy 01:06:10 Chronic Pain and Lifestyle: Why Knees and Backs are the Biggest Challenges 01:09:32 Finding Quality Care: The Network of Trusted Regenerative Physicians 01:12:46 Closing Reflections: The Joy of Bringing Patients Back to an Active Life     Thank You to Our Sponsors: EnergyBits: Get 20% off your entire order by going to https://energybits.com/ and using code DARIN at checkout. Fatty15: Get an additional 15% off their 90-day subscription Starter Kit by going to fatty15.com/DARIN and using code DARIN at checkout.     Find More from Dr. Christopher Rogers Website: San Diego Orthobiologics Medical Group Instagram: @sandiegoorthobiologics     Find More from Darin Olien: Instagram: @darinolien Podcast: SuperLife Podcast Website: superlife.com Book: Fatal Conveniences     Key Takeaway "Your body was designed to heal — not just manage pain. When we stop suppressing symptoms and start supporting biology, we unlock the intelligence that's been there since the day we were born."  

Send us a text2025 was a year of massive shifts and powerful transitions. But how can we just reflect, digest, and process it all so we can turn it all into fuel to be our baddest bitch selves as we go into 2026? In this episode of CosmicRX Radio, we sit down with Zoey Greco, beloved spiritual coach and podcaster, to reflect on 2025: from numerology to astrology, from the collective challenges to the personal breakthroughs, and more.Zoey Greco, also known as "The Merhipsy", is an intuitive empath and spiritual coach, whose work connects individuals to the divine guidance and unconditional love that awaits them in every moment from Universal energy. Through her podcast, her Intuition Activation Mentorship, and through her twice sold out Mystic Rebel Oracle and Crystal decks, Zoey helps others experience healing, discover community, and feel far less alone in their spiritual and personal journeys. She teaches others that we all have the power of intuition and can develop it with the use of many spiritual tools and modalities to manifest a life of endless possibilities.

China and Germany Seal Substantive Agreements at 4th Finance Dialogue, signaling stronger cooperation by Capital FM

Register for The CIRS Summit 2025! It's free! https://cirs-summit-2025.heysummit.com/ For more information and support, join us at https://thecirsgroup.com Welcome to another episode of The CIRS Group podcast with Barbara and Jacie! In today's episode, we dive into the details of the upcoming CIRS Summit 2025 happening on December 13th and 14th. The summit will have a great mix of expert interviews on a wide range of topics related to CIRS. From environmental biotoxins and brain health, to legal advice and family dynamics, there is something for everyone. We'll also talk more about how to register for the event, access replays, and contribute to CIRS research. Check out the timestamps to see who's speaking, and register here: https://cirs-summit-2025.heysummit.com/  TIMESTAMPS 00:01 The CIRS Summit 2025 01:20 This year's Summit is new and improved! 02:57 Register for the CIRS Summit 03:39 Summary of all the scheduled talks! and Disclaimer 03:58 Dr Ritchie Shoemaker - Lessons for Tomorrow from Lessons in the Past 04:33 Dr. Jennifer Smith - Complex Family Systems in CIRS 05:26 Max McCord - Diagnosing the Root Cause of Environmental Biotoxins 06:19 Dr. Andrea Jordheim - How to Improve Your Brain's Cleaning and Repair System in CIRS 07:35 Mindy Mastruserio - Reclaiming Agency in CIRS: Healing the Self Beyond the Protocol 09:10 Dr. Christian Navarro Torres - How the Latest Nasal Swab Testing Can Help You Heal 10:00 Dr. Paula Kruppstadt - A Perspective on CIRS, Autism and PANS/PANDAS from a Functional Medicine Pediatrician 10:58 Dr. Lacey Venanzi - Are you Celiac or just gluten sensitive? 12:04 Julie Helm - From Reset to Regeneration: Bridging the Shoemaker Protocol to the Bredesen Protocol 13:00 Ian Siegel - How Giftedness Becomes a Curse in a Moldy School 13:55 Louise Carder - the Leptin Connection: Satiety, Signaling and Healing 15:00 Dr. Stacey McLure - Understanding the Skin Barrier: Structure, Function and Care 15:49 Ryan Schnack - How to Build A Strong Legal Case for CIRS 16:40 Dr. April Vukelic - Tips for Managing Back and Joint Pain with CIRS 19:20 Justin Carlson - New Tools for Living Safely with CIRS: Mold Map, Find a Mold Doctor and Aerlume 22:25 Final Thoughts and how to watch for free or get the replays For more information and support, join us at https://thecirsgroup.com Order Jacie's book! The 30 Day Carnivore Bootcamp: https://a.co/d/7MgHrRs The CIRS Group: Support Community: https://thecirsgroup.com Instagram: https://www.instagram.com/thecirsgroup/ Find Jacie for carnivore, lifestyle and limbic resources: Jacie's book on the Carnivore diet!  https://a.co/d/8ZKCqz0 Instagram: https://www.instagram.com/ladycarnivory YouTube: https://www.youtube.com/@LadyCarnivory Blog: https://www.ladycarnivory.com/ Find Barbara for business/finance tips and coaching: Website: https://www.actlikebarbara.com/ Instagram: https://www.instagram.com/actlikebarbara/ YouTube: https://www.youtube.com/@actlikebarbara Jacie is a Shoemaker certified Proficiency Partner, NASM certified nutrition coach, author, and carnivore recipe developer determined to share the life changing information of carnivore and CIRS to anyone who will listen. Barbara is a business and fitness coach, CIRS and ADHD advocate, writer, speaker, and a big fan of health and freedom. Together, they co-founded The CIRS Group, an online support community to help people that are struggling with their CIRS diagnosis and treatment.

Unlocking Optimal Health: The Role of Cell SignalingIn this episode of The Healthy CEO, host Jason Wright speaks with Dr. Gus Vickery about the critical role of cell signaling in health and wellness. They explore the foundational importance of cellular communication for longevity and overall well-being. Dr. Vickery breaks down the science behind cell signaling, highlighting how disruptions can impact everything from mental clarity to energy levels. The discussion also delves into practical ways to identify and enhance cell signaling, including the significance of maintaining healthy mitochondrial and cell membranes. The duo introduces their essential nutrients stack, specifically designed to support these cellular processes, and emphasize the importance of both adding necessary nutrients and eliminating harmful elements from one's lifestyle. Whether you're looking to boost your energy, improve mental focus, or simply understand the cellular mechanisms that underpin good health, this episode offers valuable insights and actionable advice.00:00 Introduction and Guest Introduction00:16 Understanding Cell Signaling01:16 Practical Importance of Cell Signaling02:41 Engagement and Social Media Call to Action03:50 Foundational Health Stack05:18 Deep Dive into Cell Signaling10:19 Mitochondrial Health and Dysfunction25:07 Genetics and Lifestyle Factors29:13 Primary Care vs. Integrative Health32:50 Introduction to Cell Membrane Test33:05 Understanding Red Blood Cell Membrane Composition33:39 Omega-3 and Omega-6 Fatty Acids34:33 Implications of Membrane Composition on Health36:19 Universal Recipe for Healthy Membranes37:13 Phospholipids and Mitochondrial Function42:11 Formulating F2 for Membrane Health51:30 Real-World Applications and Nutrient Optimization58:58 Conclusion and Final Thoughts

11-24 Adam and Jordana 9a hour

This week on The Data Minute, Peter sits down with Vivek Ladsariya, Managing Director at Pioneer Square Labs, for a deep dive into the Seattle startup ecosystem and the evolving world of venture studios.Vivek breaks down why Seattle has become the quiet giant of AI infrastructure, holding the second-highest concentration of AI talent in the US, and explains why the "locked up" talent at Amazon and Microsoft is finally breaking free. He also gives a candid assessment of the venture studio model, why many studios are "zombies," how AI is forcing them to pivot to a holding company structure, and why he actually encourages his Seattle founders to move to San Francisco.They also discuss the economics of small funds vs. mega funds, why signaling risk is real for follow-on rounds, and the "unscalable" things emerging managers must do to compete. Plus: a look at an investment fighting the loneliness epidemic and a rare story of a VC voluntarily taking dilution to save a cap table.Subscribe to Carta's weekly Data Minute newsletter: https://carta.com/subscribe/data-newsletter-sign-up/Explore interactive startup and VC data, with Carta's Data Desk: https://carta.com/data-desk/Chapters:00:00 – Intro: Seattle, Studios, and AI01:10 – Welcome Vivek Ladsariya02:22 – How mega funds warped the SF market05:08 – Inside Pioneer Square Labs06:40 – The "Bar Test": Speed of funding in SF vs. Seattle09:23 – Is Seattle talent trapped in Big Tech?11:46 – The "Cracked Kid" vs. The Seasoned Exec15:50 – Why Seattle is the #2 AI hub in the US17:02 – Why Vivek wants Seattle founders to move to SF20:10 – The case against remote work for startups21:53 – Why Seattle is the infrastructure capital of AI24:11 – The Venture Studio model: Why do VCs hate it?27:10 – How AI is disrupting the studio model29:00 – The HoldCo future: Hims & Hers and Liquid Death31:22 – Using a studio to compete with mega-fund platforms33:45 – Why PSL will never raise a mega fund36:16 – The psychology of follow-on reserves38:56 – Signaling risk: "Why didn't Andreessen invest?"41:30 – Secondaries vs. holding onto winners45:28 – Are LPs tired of mega funds?46:31 – Why you can't be a solo GP forever48:56 – Investing in the loneliness epidemic (Tin Can)50:43 – The most value-add thing a VC can do52:07 – OutroThis presentation contains general information only and eShares, Inc. dba Carta, Inc. (“Carta”) is not, by means of this publication, rendering accounting, business, financial, investment, legal, tax, or other professional advice or services, and is for informational purposes only.  This presentation is not a substitute for such professional advice or services nor should it be used as a basis for any decision or action that may affect your business or interests. © 2025 eShares, Inc., dba Carta, Inc. All rights reserved.

Gut motility may be the most important and least discussed aspect of health. One vital part of gut motility is the Migrating Motor Complex. The Migrating Motor Complex (MMC) is the gut’s “street sweeper,” clearing food and bacteria to maintain intestinal homeostasis between meals. In this episode, we review its physiology, regulatory mechanisms, and clinical relevance – from SIBO to functional GI disorders – highlighting why this cyclical motility pattern matters for patient care. Today you’ll meet the migrating motor complex: your gut’s built-in street sweeper that clocks in when you’re not eating. This behind-the-scenes cleaning cycle is essential to GI health! Today on The Lab Report: 3:20 Gut motility – peristalsis and segmentation 5:45 Migrating Motor Complex (MMC) 8:40 Motilin, serotonin, and the vagus nerve 11:15 Acidification of the small intestine and Motilin 13:25 Signaling the vagus nerve 16:20 MMC’s role in SIBO/IMO 17:50 Prokinetics and meal spacing 22:00 Question of the Day What is the relationship between PPI’s and MMC? Additional Resources: SIBO Breath Test GI Effects Stool Profile Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: podcast@gdx.net. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.See omnystudio.com/listener for privacy information.

Jon Buscemi joins the podcast to discuss his journey from trend forecasting at DC Shoes to founding his iconic luxury sneaker brand. He shares the inside story of selling his brand to private equity and how their strategy to create an attainable luxury diffusion line was the "kiss of death", violating the rules of luxury pricing. Buscemi argues that fashion's monoculture is dead, replaced by micro-communities, and that social media has killed the discovery aspect of fashion. He details how his new members-only golf brand Redan, is built on scarcity and community, predicting that this "members-only" model is the future trend for fashion.Chapters:00:00:00 - Introduction00:03:31 - The $1000 Sneaker00:18:00 - From DC Shoes to Tribal Fashion Trends00:33:17 - Selling to Private Equity00:45:14 - Networking, Signaling, & The "Members-Only" Brand00:59:11 - Can a Monoculture Brand Still Be Built Today?Powered By:Fulfil.io.https://bit.ly/3pAp2vuThe Only Cloud ERP Designed to Efficiently Scale 8 and 9-Figure Brands. Northbeam.https://www.northbeam.io/Postscript.https://postscript.io/Richpanel.https://www.richpanel.com/?utm_source=9O&utm_medium=podcast&utm_campaign=ytdescSaras.https://bit.ly/9OP-YtdescSubscribe to The Marketing Operators Podcast here:https://www.youtube.com/@MarketingOperatorsSubscribe to The Finance Operators here:https://www.youtube.com/@FinanceOperatorsFOPSSign up to the 9 Operators newsletter here: https://9operators.com/

What makes Monash a model for modern pharmacology? Dr. Michelle Halls reveals how collaboration, mentorship, and receptor organization shape today's GPCR breakthroughs — from femtomolar signaling to cancer biology. A look inside a lab culture built on precision, openness, and impact.

Silver just got officially crowned a critical U.S. mineral, and that's sending ripples through the entire precious metals world. From tightening global supply chains to central banks quietly stacking gold, the signs of a new bull run are flashing everywhere. We'll break down why $100 silver and $5,000 gold aren't as far-fetched as they sound — and what it all means for investors like you. Grab your coffee and catch this week's Bullion Market Update before the next big move hits.

Let's talk about Trump signaling Newsom and California....

November 6, 2025 ~ WJR Senior Sports Analyst Steve Courtney joins Chris and Jamie to discuss the Detroit Pistons strong start to the season, including a 114-103 win over the Utah Jazz Wednesday night. Hosted by Simplecast, an AdsWizz company. See https://pcm.adswizz.com for information about our collection and use of personal data for advertising.

In this episode of Future Fuzz, we dive deep into marketing attribution with Scott Desgrosseilliers, Founder and CEO of Wicked Reports. With over a decade of experience and billions in ad spend analyzed, Scott reveals how most marketers are relying on broken data, and what to do about it. He introduces the Five Forces Framework, explains why ad platforms over-credit themselves, and breaks down his practical “Scale, Chill, or Kill” methodology to guide data-driven decisions that fuel real growth.If you've ever felt uncertain about which channels are actually driving your ROI, this episode is a must-listen.Guest BioScott Desgrosseilliers is the Founder and CEO of Wicked Reports, a leading first-party marketing attribution platform built for high-growth e-commerce brands. With more than 10 years in the attribution space, Scott has helped marketers track real customer journeys across platforms and channels, enabling smarter decisions and stronger returns. He's known for making complex data actionable through frameworks like Scale, Chill, Kill and the Five Forces of Attribution. Scott is also a frequent speaker and advocate for measuring what matters, new customer growth.TakeawaysMost ad platforms over-inflate their contributions, especially at the bottom of the funnel.“Scale, Chill, Kill” helps marketers make fast, confident budget decisions.The Five Forces framework aligns strategy, intention, measurement, and optimization.Attribution is about people, not just clicks, track real customer journeys with first-party data.You can't improve what you can't measure accurately.Don't just trust ROAS dashboards, verify with neutral, consistent data.AI is helpful, but attribution still requires human intelligence and context.New customer acquisition must be measured differently than repeat sales.Chapters00:00 - Intro: Why Attribution Matters 01:46 - What Wicked Reports Actually Does 02:30 - The Problems with Ad Platform Reporting 03:15 - Measuring, Signaling, and Acting on Data 04:10 - “Scale, Chill, Kill” Simplified 05:30 - Attribution vs. Strategy: Why Most Marketers Miss It 07:00 - How Bad Attribution Hurts Real Growth 08:00 - The Patriots vs. Eagles Scoreboard Analogy 09:40 - The Five Forces Framework Overview 11:00 - Why Intention Must Come Before Measurement 12:30 - Setting Expectations with “Zones” 14:00 - Why the Chill Zone Saves Time and Sanity 15:20 - Pride vs. Results: Knowing When to Kill a Campaign 16:00 - From Outcome to Optimization 17:30 - Fishing in the Right Ad Sets 18:30 - Dealing with Platform Changes and AI Shifts 20:00 - First-Party Data is Your Lifeline 21:45 - Building Content and Long-Term Attribution Assets 23:00 - Where to Find Scott and Wicked ReportsLinkedIn⁠Follow Scott on LinkedIn ⁠Follow Vince on LinkedIn

In this episode, Dr. Brendan McCarthy, Chief Medical Officer of Protea Medical Center, dives deep into estrone, one of the three key estrogens, and explains why understanding it is crucial for women's health. Learn about: The differences between estradiol, estriol, and estrone How estrone levels shift during perimenopause and menopause Why oral estrogen can dramatically increase estrone The impact of lifestyle factors like diet, body fat, stress, alcohol, and sedentary behavior on estrogen balance Practical tips to support healthy estrogen metabolism naturally Dr. McCarthy breaks down complex biochemistry in a clear, actionable way so you can take charge of your hormonal health.   Citations: 1. Bulun, Serdar E., et al. “Aromatase and Estrogen Biosynthesis in Adipose Tissue.” Endocrine Reviews, vol. 23, no. 3, 2002, pp. 305–342. 2. Labrie, Fernand, et al. “Importance of the Intracrinology of Estrogen Synthesis in Peripheral Tissues in Postmenopausal Women.” Journal of Steroid Biochemistry and Molecular Biology, vol. 118, nos. 4–5, 2010, pp. 273–279. 3. Sasano, Hironobu, and Toshihiko Harada. “Differential Expression of Aromatase and 17β-Hydroxysteroid Dehydrogenase Isoenzymes in Human Tissues.” Journal of Steroid Biochemistry and Molecular Biology, vol. 86, no. 3–5, 2003, pp. 327–333. 4. Yager, James D., and Nancy E. Davidson. “Estrogen Carcinogenesis in Breast Cancer.” New England Journal of Medicine, vol. 354, no. 3, 2006, pp. 270–282. 5. Cavalieri, Ercole L., and Eleanor G. Rogan. “Depurinating Estrogen-DNA Adducts, Mechanisms of Formation, and Prevention.” Clinical Cancer Research, vol. 16, no. 3, 2010, pp. 596–602. 6. Suba, Zsuzsanna. “Circulating Estrogens and Estrogen Metabolism in Obese Women.” Journal of Clinical Endocrinology and Metabolism, vol. 98, no. 11, 2013, pp. 4336–4344. 7. Simpson, Evan R., and Konstanze C. Pike. “Aromatase Expression in Adipose Tissue: Relationship to Obesity and Insulin Resistance.” Endocrinology, vol. 156, no. 9, 2015, pp. 3422–3435. 8. Key, Timothy J., et al. “Circulating Sex Hormones and Breast Cancer Risk Factors in Postmenopausal Women: Reanalysis of 13 Studies.” British Journal of Cancer, vol. 105, no. 5, 2011, pp. 709–722. 9. Stanczyk, Frank Z., et al. “Oral, Transdermal and Injectable Hormone Therapy: Pharmacokinetics and Effects on Estrone/Estradiol Ratios.” Menopause, vol. 24, no. 9, 2017, pp. 1080–1090. 10. Santen, Richard J., et al. “Estrogen Bioidentical Hormone Therapy: Route of Administration and Risk.” Journal of Clinical Endocrinology and Metabolism, vol. 105, no. 7, 2020, pp. 2062–2074. 11. Zeleniuch-Jacquotte, Anne, et al. “Postmenopausal Levels of Estrone, Estradiol, and Estrone Sulfate and Breast Cancer Risk.” Cancer Epidemiology, Biomarkers & Prevention, vol. 23, no. 8, 2014, pp. 1531–1539. 12. Dall, Gabriella V., and Christine L. Clarke. “Local Estrogen Biosynthesis and Signaling in Breast Cancer Progression.” Steroids, vol. 78, no. 7, 2013, pp. 639–646. 13. Heald, Anthony H., et al. “Relationships Between Serum Estrone, Insulin Resistance, and Adiposity in Postmenopausal Women.” Clinical Endocrinology, vol. 67, no. 3, 2007, pp. 340–345. 14. Kuiper, George G. J. M., et al. “Estrogen Receptor β Selectivity of Estriol and Implications for Tissue-Specific Effects.” PNAS, vol. 94, no. 17, 1997, pp. 9105–9110. 15. Michnovicz, Joseph J., et al. “Dietary Indoles and Estrogen Metabolism: Effects of Cruciferous Vegetable Intake.” Journal of Nutrition, vol. 134, no. 12, 2004, pp. 3479S–   Dr. Brendan McCarthy is the founder and Chief Medical Officer of Protea Medical Center in Arizona. With over two decades of experience, he's helped thousands of patients navigate hormonal imbalances using bioidentical HRT, nutrition, and root-cause medicine. He's also taught and mentored other physicians on integrative approaches to hormone therapy, weight loss, fertility, and more. If you're ready to take your health seriously, this podcast is a great place to start.  

How have politics changed from the  Bill Clinton era to that of  Donald Trump? How have identity politics diverted attention from economic issues, and how have the educated elites derailed activism?Fredrik deBoer is the author of both fiction and nonfiction works, including The Mind Reels, The Cult of Smart: How Our Broken Education System Perpetuates Social Injustice, and How Elites Ate the Social Justice Movement.Greg and Fredrik discuss the American political left and why the left-right dichotomy fails to tell the complete story.  Fredrik provides a critical examination of the internal divisions within the political left, identity politics, and the impact of social media on political engagement. He argues that the left's preoccupation with symbolic issues often undermines its ability to build broad-based coalitions, and suggests a return to class-first politics as a more effective strategy. They also touch on the role of nonprofits, the evolution of meritocracy in education, and the challenges of achieving genuine economic and social justice.*unSILOed Podcast is produced by University FM.*Episode Quotes:How social media turned politics into identity performance45:28: What makes all of this particularly more pernicious in the 21st century is, it's not just now your immediate peer group of people you see face-to-face. You've got to answer to a couple thousand people on social media who know your name and who know where you work, and who will yell at you if you have the, quote-unquote, wrong position. Right? And this is a thing that has happened all over the world of the left, which is, cultural issues began to be foregrounded above economic issues to an extreme extent. There was a development of a very narrow sort of list of approved opinions that you could hold on cultural and social issues. They came to be seen as sort of outside of the realm of politics, and without anyone actually intending for it to happen, what the sort of default young Democrat in politics was shifted over time in an extreme identitarian direction.When politics becomes a team sport, everyone loses nuance29:18: I think we are just training generations of young people who do not understand politics as anything other than a sort of blood sport, organized around a very simplistic binary.The heart of politics is empathy, not ideology07:23: I have a very long list of disagreements with Bill Clinton, but he was a political genius, and everyone knows, his signature phrase is, I feel your pain. And to me, that's the heart of politics. It's saying, I understand that you need something, and I'm here for you. In that sense, the identity politics on the left in the last 15 years has been about telling large groups of people that they do not have real problems, right? So, if you go show up to a university campus and you start to talk about some of the problems that afflict, for example, the white working class, you'll be told quite directly, oh, to center the white working class, right, is to privilege racism and blah, blah, blah, blah, blah, blah, right? It's saying directly to these people, your problems are not real problems. And so, like, that's the perfect example of where you are sacrificing potential allies for a benefit that I just do not even understand.Show Links:Recommended Resources:SocialismMarxismProgressivismSingle-Payer HealthcareBill ClintonDonald TrumpAdolph L. Reed Jr.Paul IngrassiaOccupy Wall StreetIron Law of OligarchyRobert ReichBarack ObamaGuest Profile:FredrikdeBoer.comWikipedia ProfileFredrik deBoer SubstackGuest Work:Amazon Author PageThe Mind ReelsThe Cult of Smart: How Our Broken Education System Perpetuates Social InjusticeHow Elites Ate the Social Justice MovementRelated UnSILOed episodes:Michael Spence - A Deep Dive into Signaling and Market Dynamics Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

China's Military Purge Signals Deep Crisis of Confidence in Xi Jinping. Charles Burton and Gordon Chang discuss how China expelled eight senior generals, signaling a severe internal crisis and lack of confidence in Xi Jinping's leadership, potentially orchestrated by his adversaries. This turmoil suggests foreign governments should interact carefully with Xi. Economically, figures show industrial production outpacing consumption, and proposals for mandated municipal consumption goals reflect a state struggling to maintain prosperity, leading to pervasive gloom among the people. 1879

China's Military Purge Signals Deep Crisis of Confidence in Xi Jinping. Charles Burton and Gordon Chang discuss how China expelled eight senior generals, signaling a severe internal crisis and lack of confidence in Xi Jinping's leadership, potentially orchestrated by his adversaries. This turmoil suggests foreign governments should interact carefully with Xi. Economically, figures show industrial production outpacing consumption, and proposals for mandated municipal consumption goals reflect a state struggling to maintain prosperity, leading to pervasive gloom among the people. 1925

Judd Kessler discusses how to navigate the hidden markets that decide how scarce resources—like time and attention—get distributed.— YOU'LL LEARN — 1) Why some people seem to score more coveted resources2) The counterintuitive advantages of settling3) An easy way to become the more appealing candidateSubscribe or visit AwesomeAtYourJob.com/ep1102 for clickable versions of the links below. — ABOUT JUDD — Judd B. Kessler is the author of LUCKY BY DESIGN: The Hidden Economics You Need to Get More of What You Want and the inaugural Howard Marks Endowed Professor of Business Economics and Public Policy at the University of Pennsylvania's Wharton School. For his work on the hidden market of organ allocation, Kessler was named one of the “30 under 30” in Law and Policy by Forbes. He is an award-winning teacher as well as a sought-after speaker.• Book: Lucky by Design: The Hidden Economics You Need to Get More of What You Want• Book site: GetLuckyByDesign.com• LinkedIn: Judd Kessler• Website: JuddBKessler.com— RESOURCES MENTIONED IN THE SHOW — • Study: “Propose with a rose? Signaling in internet dating markets” by Soohyung Lee and Muriel Niederle• Book: Basic Economics by Thomas Sowell• Book: Who Gets What — and Why: The New Economics of Matchmaking and Market Design by Alvin Roth• Past episode: 015: David Allen, The World's Leading Authority on Productivity• Past episode: 482: David Allen Returns with the 10 Moves to Stress-Free Productivity• Past episode: 1090: How to Get Recruiters to Compete for You with Madeline Mann— THANK YOU SPONSORS! — • Strawberry.me. Claim your $50 credit and build momentum in your career with Strawberry.me/Awesome• Vanguard. Give your clients consistent results year in and year out with vanguard.com/AUDIO• Quince. Get free shipping and 365-day returns on your order with Quince.com/AwesomeSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

JACC Editor-in-Chief Harlan M. Krumholz, MD, SM, introduces the October 21, 2025 issue of JACC, which is devoted entirely to Dr. Milton Packer's adipokine hypothesis.  Dr. Krumholz explains the rationale behind dedicating the issue to this bold conceptual framework, which proposes that dysfunctional visceral fat and its secreted adipokines drive HFpEF. We're also thrilled to present readers with 10 accompanying expert commentaries that explore, challenge, and contextualize the hypothesis.

In this week's message, Pastor Kirt shared the story of the widow's mite — a reminder that true generosity flows not from abundance, but from the heart. While religious leaders of Jesus' time sought recognition and power, this humble widow quietly gave all she had, embodying sincere devotion. Jesus saw and honored her gift, showing that God values the spirit of giving more than the size of the offering. We are called to give out of gratitude, not obligation, recognizing that every act of love and service reflects God's own generosity. May our giving — in time, effort, and care — glorify Him who has given us everything.

HEADLINE: Commodities Rise and UK Flag Controversy: French Weather, Market Trends, and British Politics GUEST NAME: Simon Constable SUMMARY: John Batchelor speaks with Simon Constable about key commodities like copper up 16% and steel up 15% signaling strong economic demand. Coffee prices remain very high at 52% increase. The conversation addresses French political turmoil, though non-citizens cannot vote. In the UK, the St. George's flag has become highly controversial, viewed by some as associated with racism, unlike the Union Jack. This flag controversy reflects a desire among segments like the white working class to assert English identity. 1913 OXFORD AND THE COTSWOLDS

HEADLINE: Commodities Rise and UK Flag Controversy: French Weather, Market Trends, and British Politics GUEST NAME: Simon Constable SUMMARY: John Batchelor speaks with Simon Constable about key commodities like copper up 16% and steel up 15% signaling strong economic demand. Coffee prices remain very high at 52% increase. The conversation addresses French political turmoil, though non-citizens cannot vote. In the UK, the St. George's flag has become highly controversial, viewed by some as associated with racism, unlike the Union Jack. This flag controversy reflects a desire among segments like the white working class to assert English identity.

Are all of these moves signaling the Browns had a plan at quarterback?

Judy Dempsey notes that Russian drone activities are prompting several European nations to seek a collective "drone wall" and coordinate defense efforts independent of US leadership, signaling a shift in the transatlantic relationship. She highlights positive pro-European election results in Moldova and a temporary halt to the far-right AfD's momentum in German local elections. Europe remains hesitant about the Gaza plan but expects to contribute to reconstruction.

Judy Dempsey notes that Russian drone activities are prompting several European nations to seek a collective "drone wall" and coordinate defense efforts independent of US leadership, signaling a shift in the transatlantic relationship. She highlights positive pro-European election results in Moldova and a temporary halt to the far-right AfD's momentum in German local elections. Europe remains hesitant about the Gaza plan but expects to contribute to reconstruction. 1940 DANUBE

For decades, while the rest of the world's powers have distracted and tangled themselves with wars of choice and blunder, the People's Republic of China has been watching, learning, and building. To what end?Returning to Midrats to discuss this and more will be Dean Cheng.Dean is a Senior Advisor, United States Institute of Peace; Non-resident Senior Fellow, Potomac Institute for Policy Studies; Non-resident Fellow, George Washington University Space Policy Institute.He recently retired after 13 years with the Heritage Foundation, where he was a senior research fellow on Chinese political and security affairs, and wrote on various aspects of Chinese foreign and defense policy.Prior to joining the Heritage Foundation, he was a senior analyst with the China Studies Division (previously, Project Asia) at CNA from 2001-2009.Before joining CNA, he was a senior analyst with Science Applications International Corporation (SAIC) from 1996-2001. From 1993-1995, he was an analyst with the US Congress' Office of Technology Assessment in the International Security and Space Division, where he studied the Chinese defense industrial complex.He is the author of the book Cyber Dragon: Inside China's Information Warfare and Cyber Operations (NY: Praeger Publishing, 2016), as well as a number of papers and book chapters examining various aspects of Chinese security affairs.Show LinksXi Jinping hails ‘unstoppable' China at landmark military parade, Financial TimesMore than pageantry, China's military parade shows off new missiles, drones and other equipment, The IndependentYJ-15 missile, YJ-19, YJ-17, YJ-20 hypersonic missiles, Global TimesNASA Names Astronauts to Next Moon Mission, First Crew Under ArtemisSummaryIn this conversation, Dean Cheng and the hosts discuss the implications of China's recent military parade, the evolution of its nuclear capabilities, and the modernization of its conventional military forces. They focus on China's ambition to establish a new world order and the strategic importance of its space and cyber capabilities. The discussion also touches on the role of coercion and deterrence in China's military strategy, as well as the challenges posed by its growing influence on the global stage.TakeawaysChina's military parade reflects its growing power and ambition.The presence of foreign leaders at the parade indicates shifting alliances.China is expanding its nuclear capabilities significantly.The PLA is focusing on both conventional and nuclear modernization.China's approach to military strategy includes both coercion and deterrence.The Chinese space program aims for long-term presence on the moon.China's cyber capabilities are evolving rapidly and pose a threat.The PLA's indigenous production capabilities are improving.China's military strategy is influenced by its historical context.The geopolitical landscape is changing with China's rise.Chapters00:00: Introduction to the Discussion on China and Military Parades03:07: Analysis of the Recent Military Parade and Its Implications06:05: The Evolution of China's Nuclear Capabilities12:07: China's Conventional Military Strategy and Modernization16:04: China's Global Influence and New World Order20:06: The Role of Coercion and Deterrence in Chinese Strategy26:12: China's Space Program and Technological Advancements34:59: China's Cyber and Information Warfare Capabilities43:46: The Future of China's Military and Strategic Developments

PREVIEW: Russia's MiG-31 Violation Over Estonia Signals Hypersonic Missile Capability GUEST: General Blaine Holt SUMMARY: Russia used the old MiG-31K model (last made in 1994) to violate Estonia's airspace, signaling air force capability, specifically its ability to carry the nuclear-capable Kinzhal hypersonic missile. 1945 ZHUKOV

September 19th, 2025 - We welcome back Robert Nugent to talk Ireland's next president and Pope Leo XIV. Then we're joined again by Dr. Anthony Stine of Return to Tradition to discuss Pope Leo's interview with Crux. TheStationOfTheCross.com/ACT  

Geoff and Marie's Good Life: Part 15The Live Sex ShowGeoffrey performs in public.Based on posts by Only In My Mind, in 15 parts. Listen to the Podcast at Explicit Novels.We were sitting cuddling together on the sofa when Colin arrived, with Mia in tow. Angie had offered to cook that afternoon and we were trying to decide what we fancied. I suggested a chilli con carne with rice. Angie decided otherwise."Kids," she called. They wandered in from the kitchen with glasses of milk and a chocolate biscuit each."If I go shopping for ingredients, would you two help me cook tea tonight?" The two teens shared a look and agreed. "Right," she announced, standing up. "Go and sort out your homework with grandad; I'll go shopping."I stood and went to get my wallet. She glared at me. "Go on. Do it," she challenged me. "I bloody dare you to offer me money to get food for the people I care about."I carefully closed the drawer and apologized for my insensitivity. "I just don't want you to think that we take you for granted," I explained.Her expression softened. "And if I ever feel that way, I'll say something, but right now it's my turn to give. Please allow me that."I went and pulled her into a hug. "Sorry Angie. You know I wouldn't deliberately upset you. Am I forgiven?"She returned my hug. "You were never in trouble. I was just reminding you that we're family now and I want to contribute too."She gave me another squeeze, a brief kiss and she left. I turned to the kids, who had watched our exchange, fascinated. "What?" I asked.Colin shook his head. "Not sure about this whole adult relationship stuff," he griped. "They are all weird." Mia smiled at his comment, but didn't argue. To be fair, the lad had a point."Okay." I clapped my hands. "Homework?"It turned out that they were studying climate change. Their teacher had given the class three questions and they were free to choose which one to answer. I suggested that Colin and Mia avoided answering the same question so they weren't accused of copying, and sent them off to the study.Angie was back and in the kitchen laying out her ingredients when the teens finally reappeared. Colin, ever the gentleman, had allowed Mia to use our laptop for her slides, while he had used my tablet. That was fine; it wasn't as though we regularly used our devices to cruise porn sites. Besides, I had made sure that Marie knew to use private tabs if she was viewing adult content. The kids were old enough to start learning about relationships. Images of explicit sex were not on their agenda for some years to come.I sent them in to the kitchen and, with their permission, went to check over their homework. I was reassured. If I had seen job applications written that thoughtfully, they both definitely would have qualified for an interview.I joined the others in the kitchen, only to find that I was redundant. Colin was slicing an onion, Mia was chopping mushrooms and Angie was trimming what looked like a pork fillet. She looked up and shook he head, smiling. "The sous chefs are doing fine," she explained. "I want them to feel confident that they can work without being micro-managed."I watched Colin. He was doing well. Slow, perhaps, but careful. Mia was taking equal care to have all the slices of mushroom a similar thickness."Shall I set the table then?" I suggested. The consensus was that yes, I could perhaps make myself useful that way."Set for a starter, main and dessert, please," Angie advised me. "We have a full menu planned.""Wine?""A nice white, maybe an oaked chardonnay," suggested Colin. "I checked on my phone," he explained, in response to my surprised expression.I grunted and went to set about my assigned tasks, and that was how Marie found me when she returned from work. "That's my job when you're the cook," she observed."I have been supplanted by our wicked betrothed and her evil teen minions," I sulked."That's nice, dear," she said, absently, as she bustled about putting her coat away.We went into the kitchen together once I had finished. My wife walked up behind Angie and gave her a big hug. "Geoffrey is feeling emasculated," she told her friend. The minions looked on in amusement.Angie gave a derisive snort. "It's my turn to cook with the kids because I'm here today. Geoff can take his turn any day.""There you go, Geoff," my wife reassured me. "We still enjoy your cooking, it's just that Angie gets less opportunity." Seeing as how I was only pretending to be upset, it was easy to pretend that all was forgiven. I accepted the explanation with a kiss for both of my girls and went off in search of a bottle of wine.I sat and red, while Marie and Angie caught up in the kitchen. Marie joined me ten minutes later. "Angie's bursting to tell me about her day, but all she dare say in front of the kids is that you and she had a pleasant afternoon."I glanced at the door. "I don't think we should have this conversation here and now. If one of the youngsters walks in, the guilty silence will just be uncomfortable for everyone. So how was your day?"And so we sat and I listened to her accounts of generous donors, sweet natured old ladies and the occasional twat who tried to bargain down the price on the ticket. For Fuck's sake! It's a charity shop. And Marie was clear; the worst offenders were most obviously not short of change. They were just tight bastards. Not that my beloved ever capitulated. She would just smile sweetly and remind them where they were, pointing out that they were welcome to try the same approach in John Lewis with her full support.We made the occasional foray to the kitchen but our offers of help were politely, but firmly, rebuffed. To be fair, the atmosphere was relaxed. I asked about the menu and, after looking to the chef for approval, Mia ran through it. "We are starting with cubes of baked breaded brie on a bed of salad with a lingonberry relish. Then there is pork stroganoff with green vegetables and rice. For dessert we are having individual warm pear frangipane tartlets with chocolate sauce and vanilla ice cream." She paused. "Oh, yes," she continued. "If anyone is still hungry there's a selection of cheeses as well as olives, and some nice bread to go with dipping oils and vinegars."I did a quick calculation in my head. "At today's prices, I reckon that meal would come in at about £50 plus per head just in a country pub." Mia just grinned at me. I carried on. "Can I afford to get used to eating like this?"I looked around the kitchen brigade and saw three unreasonably happy cooks. Angie was obviously less demanding of the children and seemed thrilled to be able to pass on her knowledge. Colin just loved cooking and Mia seemed to be determined to learn so that she could help her mum.I turned to Angie. "This all smells wonderful. Wendy and Linda should both be here well before six. Is that okay, Chef?"Angie looked at her team. "Starters on the pass for six o'clock.""Yes Chef!" They shouted in unison. We shook our heads and left them to it.Wendy arrived first. Mia had sent her a text to say that they were eating at our place again. Wendy tried to apologize for intruding but we, particularly Marie, were having none of it. "We love having Mia with us. I know she's very mature but, as Colin is here anyway, it makes no sense for her to be at home, alone," my wife told her. "In addition, Angie is doing a cookery masterclass and she is way more tolerant of the kids than she is with me, so it's easier just to let them get on with it."Mia must have heard her mum's voice because she left the kitchen, briefly, to give her mum a hug before apologizing. "Sorry mum, but I need to turn the tarts so they brown evenly." And, with that, she dashed back to the kitchen. We led a bemused Wendy to the living room, sat her down and asked about her day. Her eyes filled as she explained just how grateful she was not to come home to have to start cooking a meal, even just for one night. She had a decent job in the Civil Service so money wasn't too much of a problem. She just struggled finding time to be the wage earner, housekeeper and mum. She felt guilty too that Mia seemed to feel obliged to sacrifice her spare time to help around the house rather than being a teenager.Marie glanced at me. We're not telepathic but I was certain we were thinking the same thing. Wendy was so caught up in being the perfect single parent, she had forgotten how to be Wendy.We never really got the chance, that evening anyway, to pursue that thought as we heard the front door open to herald our daughter's arrival. What followed, by then, seemed oddly familiar. Hearing his mother greeting us, Colin emerged from the kitchen, hugged his mum, and promptly departed, shouting over his shoulder, "Sorry mum. Got to dash. I can't let the rice overcook. Love you."Linda appeared as flummoxed as Wendy had. "I don't know what it is about this house, but there always seems to be something odd going on just lately." Wendy looked at her in surprise. "What?" my daughter retorted. "How many other throuple weddings have you been invited to? Even more particularly, how many with a Star Wars dress code?" She shook her head. "Christ, I hope it isn't genetic; otherwise I'm well and truly fucked!" She put her hand to her mouth guiltily and checked to see that neither of the youngsters had overheard. "Sorry all. That just slipped out," she apologized. "I've had a weird day at work too. Some half-wit manager wanted me to;” She did the 'air-quotes' with her fingers. "; Expedite a delivery to an important client in Nice.""Let's sit down and you can vent in comfort," I suggested. I led our daughter through and Marie followed with Wendy. "Now, go on. Story so far, idiot, big words, France. New readers start here."She explained that, in order to cover his ass for something that his team had screwed up, said half-wit tried to make it Linda's problem to solve. The vehicle in question was already in France and the driver had to observe French law. The only way to 'expedite' the delivery would be to exceed his permitted hours or fly another driver out to take over; neither was going to happen. Being Marie's daughter, of course she just picked up the phone and asked the operations manager for a cost code for the air fare from Gatwick to Lyon. Apparently the idiot had just assumed that Linda, being a woman could just, who knows? Make it go away?Ops manager had obviously queried the request and Linda, quite disingenuously, told him. It was not well received. She sighed. "On the upside, I got the problem back where it belongs. On the other hand, now I have to watch my back in case he tries to retaliate." She took a deep breath and sat back. "Thank you." We must have looked puzzled. "For just listening and not telling me what I should have done," she explained. She thought for a moment. "This place is still weird though."As she finished that thought, Colin appeared from the kitchen with a white napkin over his arm, to invite us take our places at the table. Linda looked at me. "See?" She mouthed. I could only grin in reply.We took our seats as directed and were joined by Angie and Mia. Colin disappeared to the kitchen and returned with the bottle of wine I had selected and placed in the fridge earlier. Handing it to me to open he returned to the kitchen. Angie cleared her throat. "Wendy, Linda; would you be prepared to let Mia and Colin have a small glass of wine with their meal? They have put their hearts into preparing it; it seems unfair that they miss out on that one component."Mia sat, apparently startled, and watched as her mother considered Angie's request. Wendy nodded slowly. "That seems fair. I'd rather she experienced alcohol in a civilized setting like this." She looked around the table. "Rather than getting hammered at her first student party at Uni."Linda nodded in agreement. "I'll get some glasses for them." Colin reappeared carrying three plates that he placed in front of Angie, Marie and Wendy. He made the journey again, this time serving Linda, Mia and me. He made the final trip for his own starter. As he sat, I reached across and poured a half measure of wine into his glass. He looked to his mum for reassurance. She smiled in acknowledgement. I poured a similar glass for Mia and then shared the remainder amongst the adults.I picked up my glass. "Ladies, Colin, a toast to the Chef and her crew." We four non-cooks raised our glasses in tribute; the cooks acknowledged our compliment and then joined in the toast. Then we attacked the food. The brie was delicious and matched beautifully with the sweet fruit jam. I watched surreptitiously as Colin finished a mouthful and self-consciously took a sip of wine. His brow furrowed as he reconciled the flavors of the wine and the food. He went back to his food looking thoughtful. We finished the starter and complimented the cooks on the flavor and the presentation. It had looked as good as it tasted.We moved onto the main course. Angie and Mia plated up in the kitchen, while Colin worked 'front of house'. Again, the meal was delicious. Angie's version was discs of pork in an onion and mushroom sauce made with crème fraiche, Dijon mustard and smoked paprika, finished with a hint of lemon juice. The plain white rice was perfect for soaking up the sauce.Colin sipped his wine again. "It tastes different with this course," he commented. "It still works but in a different way." He looked to Mia for opinion."Is it because the lingonberry was so sweet that the wine tasted sharper?" She asked me.I shrugged. "Probably. It might even be something to do with the lactic acid in the crème fraiche. What matters is whether you like it.""I do," she smiled and turned to Angie. "Thank you;” She hesitated. "I'm sorry. But I don't know what to call you.""Grangie," offered Colin."Or Angie," suggested our fiancée.Wendy seemed uncomfortable. "Isn't that a bit familiar? Wouldn't Mrs. and your surname be more appropriate?""Technically," interjected Linda. "If you were going to insist that we stand on ceremony, Mia should address Angie as Professor Weston." She frowned at the thought. "Nope. This place is weird enough already. Angie or Grangie. He's Geoff or grandad; that's Marie or grandma and I'm Linda. We want you and Mia to be comfortable here."Mia considered. "Thank you Angie for getting mum and Linda to let us have wine with the meal.""You both earned it dear," Angie assured her. "Now. Desserts, I think."Again, the two girls plated as Colin served. The tartlets looked amazing; a light short crust pastry filled with an almond flavored sponge topped with poached pear cubes. On each plate there was a swirl of chocolate sauce over a generous quenelle of vanilla ice-cream, starting to melt where it touched the still warm tart. I knew where Angie had gone shopping for the ingredients for the meal, and the small fragrant black specks confirmed that she had not economized on cheap ice-cream. This was made with actual vanilla pods. The aroma from the plate was amazing; it was all that I could do not to dive straight in. Still, manners required that I wait until everyone was served, so that's what I did.Once Colin was seated, we began. The taste was amazing. I glanced towards Angie in inquiry. "Star anise as well as cinnamon," she clarified. I nodded, impressed, and turned back to my dessert and savored the remainder. I watched as Colin took another sip of his wine and then Mia as she followed suit. Colin actually shuddered. Mia merely looked disappointed."Have a sip of water," I suggested. "And then wait a couple of minutes after you've finished eating."After the seven plates were all but polished clean, we thanked our catering team. It had been an absolutely lovely meal and the final course had been a triumph. Linda and Marie stood to clear the table, but returned immediately to sit with our guests and chat as we finished our wine."I've never eaten like that before," Wendy admitted."At home, you mean?" Asked Linda.Wendy shook her head. "Ever. My husband didn't like 'fancy foreign muck' so it was fish and chips, takeaways or just ready meals." Her voice cracked with emotion. "Even now, most of our meals are out of the freezer. I can boil potatoes and grill sausages and reheat tinned or frozen veg. My dad just liked the same old stuff too, so that's all my mum taught me. That's about my limit. At this moment," she admitted, sadly, "Mia's almost certainly a better cook than I am."Angie surprised me. She isn't always the most diplomatic of us. "Being untutored is not the same as being a failure." She reached for Wendy's hand. "Tell us how we can help, and between us, you have a group of capable cooks here who are happy to teach you whatever we can."Marie and I finished our drinks and Linda joined us in the kitchen. The brigade had washed and tidied as they went so there was only really the crockery to deal with. That went in the dishwasher. We cleaned the hob and worktops and sorted out the saucepans then returned to the living room. The teens had disappeared, leaving Angie and Wendy talking about food.When Wendy confessed that she would struggle to even shop for a meal such as we'd just had, Linda made a contribution. "A girl I work with wanted to branch out from the same old stuff she always cooks, so she orders from one of those on-line delivery companies. She swears by them now." She picked up her phone. "I can call her and if you decide to do it and say she recommended them to you, then you'll both get a discount."Wendy looked uncertain. The poor woman had no self-confidence at all. Linda left the room and returned two minutes later scrolling on her phone. "Here," she said, passing her phone to Wendy. "Jan told me how to install their app. Pick four meals for two people from this menu list and you'll get everything you need delivered next week, along with recipe cards. Jan said the instructions are dead simple and she's actually learning to cook from doing it."Wend called for Mia to come and choose with her and, together they picked four meals that they thought they might enjoy cooking together. While they did, Colin and I chatted about his first experience of wine with a meal. "It tasted nice, except with dessert," he told me. "Would a sweeter wine have been nicer?""Probably," I acknowledged. "There's a lot of snobbery and nonsense about wine, but some types do go with some foods better than others. I didn't find it clashed to the extent that you did, so personal preference and experience play a part too."At that point Mia called him over to see what she and her mum had chosen for the following week. He pointed to one selection. "Grandma makes that sometimes. It's ace."Wendy passed the phone back to Linda and the pair completed the sign up and the first order, making sure to claim the discount. Wendy seemed conflicted. "I'm a bit nervous about having to make something I've never done before," she confessed. "But I'm excited at the same time.""Think of this," my wife suggested. "As long as you have a loaf of bread, a tin of baked beans and some cheese in the house, even if it all goes horribly wrong, at least you won't starve."The conversations about food carried on until Wendy looked at her watch. "Oh goodness," she exclaimed. "Look at the time!" And after collecting Mia and thanking us for our hospitality, within ten minutes they were gone.Linda pulled me into the kitchen. "That poor girl's husband did a proper number on her: the bastard," she spat. "She copes okay at work because she knows her job. But as a person;” She paused, speechless."I know, sweetheart. We all do. And she's such a lovely woman too."She stared at me, suspiciously. "Are you three planning something?""No," I answered, sort of honestly. "But if an opportunity presents itself, we would probably try to help her see what a worthy person she is."

This week join Izzah Wahab for a discussion of her research on estrogren, specifically E1, and how it uses he GPCR signaling paradigm in relation to cancer progression. For upcoming interviews check out the Grad Chat webpage on Queen's University School of Graduate Studies & Postdoctoral Affairs website – https://www.queensu.ca/grad-postdoc/research/share/grad-chat

John Hardie Bill Roggio. Russia Intensifies Ukraine Barrage; Trump Faces Pressure for Stronger Sanctions. Russia launched a massive drone and missile attack on Ukraine, signaling Putin's refusal to negotiate. President Trumpfaces pressure to implement tougher sanctions on Russian oil revenue. Ukraine faces infantry shortages and porous lines but is improving air defenses. Russian advances are slow, struggling to exploit Ukrainian vulnerabilities on the battlefield. 1859 Odesa

CONTINUED  John HardIe. Bill Roggio.  Russia Intensifies Ukraine Barrage; Trump Faces Pressure for Stronger Sanctions. Russia launched a massive drone and missile attack on Ukraine, signaling Putin's refusal to negotiate. President Trumpfaces pressure to implement tougher sanctions on Russian oil revenue. Ukraine faces infantry shortages and porous lines but is improving air defenses. Russian advances are slow, struggling to exploit Ukrainian vulnerabilities on the battlefield. 1855 BRITISH CRIMEA

PREVIEW:  Malcolm Hoenlein: Iraq accuses Iran of disguising its crude as Iraqi exports to bypass sanctions, launching a high-level probe into the oil smuggling network, signaling a major relationship shift. MORE LATER. 1900 BAGHDAD 

Jeremy Au broke down how venture capital funds design LP decks, allocate capital, and differentiate themselves in competitive markets. The discussion covered portfolio construction math, capital call strategy, the role of opportunity funds, and how funds highlight unique value-adds like founder wellness programs. 02:12 Capital Calls and Timing Funds usually deploy half their capital in the first two years, with follow-ons between years two to five, balancing liquidity with legal cost efficiency. 04:15 Marking Winners and Power Laws Most of a fund's value, about 60 to 75 percent, often comes from one breakout company, driving the case for raising opportunity funds to double down. 07:27 Signaling with Follow-On Investors A strong follow-on rate signals quality to LPs. “If your companies are all Ds and shit, then nobody's gonna come in.” Watch, listen or read the full insight at  https://www.bravesea.com/blog/inside-lp-deck Get transcripts, startup resources & community discussions at www.bravesea.com WhatsApp: https://whatsapp.com/channel/0029VakR55X6BIElUEvkN02e TikTok: https://www.tiktok.com/@jeremyau Instagram: https://www.instagram.com/jeremyauz Twitter: https://twitter.com/jeremyau LinkedIn: https://www.linkedin.com/company/bravesea English: Spotify | YouTube | Apple Podcasts Bahasa Indonesia: Spotify | YouTube | Apple Podcasts Chinese: Spotify | YouTube | Apple Podcasts Vietnamese: Spotify | YouTube | Apple Podcasts

Drs. Zubair Ansari and Basil Williams join for a candid discussion regarding the state of the ophthalmology residency match, including a discussion of dropping match percentages and the introduction of preference signaling.

Jennifer Oliver is an experienced commercial litigator who has defended consumer class actions and multidistrict litigation, including those arising from data breaches and antitrust. She has worked in several high-profile jury trials, serving as lead counsel in complex mediations. She also counsels clients on matters related to privacy compliance and use of ad tech and similar technologies.Jennifer is a shareholder at Buchanan, Ingersoll & Rooney and has a long list of relevant affiliations and certifications including being an Executive Committee Member of the Privacy Section at the California Lawyers Association.With Jennifer we have dived deeper into AdTech or pixel-related litigation in California, both in court and through arbitration.References:* Jennifer Oliver on LinkedIn* Jennifer Oliver's profile at Buchanan* John Pavolotsky: How successful can US privacy laws be at regulating AI models and systems? (Masters of Privacy)* California SB 690 Passes California's Senate, Signaling a Major Step in Redefining Privacy Law and Limiting CIPA Litigation for Online Businesses This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.mastersofprivacy.com/subscribe

Stocks surge to new records following Fed Chair Jerome Powell's speech in Jackson Hole. Signaling he could be open to lowering rates at the September meeting. Cleveland Fed President Beth Hammack joins the show – with her first reaction to those remarks. Then Intuit a rare tech stock in the red after reporting results. CEO Sasan Goodarzi breaks down the quarter. Plus following Powell, what's the next catalyst for the market? Could it be Nvidia results next week? We break down some of the challenges facing the company.

This episode features an interview with Casey Hill, CMO at DoWhatWorks, a company that removes the guesswork from website optimization, tracking millions of websites daily to find winning A/B tests from major brands.Casey provides actionable advice on effective thought leadership, influencer marketing, and various ways to optimize your website. Key Takeaways:Promoting customer's posts about your company can be a great way to spread an outside vantage point, and customers are typically happy to have you pay to promote their pages. Test all your assumptions and learn what makes sense for your business. Try to test components of your website that you may not have initially thought to look into. Be cautious when it comes to social proof and unintended signalling with third party reviews. A lot of marketers do this poorly. Quote:   Most people do social proof really poorly. The way now, and this is across the board, so we talked about logos, but it also applies to G2 reviews or third party reviews. I think people don't pay attention enough to unintended signaling. Like someone puts 4.4 stars with 300 plus reviews and someone sees that, and that might actually might be a negative signal, right? And so like they look at that, they're like, 'oh, I thought you were much bigger. You only have 300 reviews.' Or in our world today is 4.4 good or bad, right? Like some people might see 4.4, like if I see it on a restaurant or I'm like, eh it's okay. Like it's kind of a neutral one to me, right? So I think you wanna be really careful about unintended signaling.Episode Timestamps: *(07:32) The Trust Tree: Create content that will be shared by other outlets*(20:30) The Playbook: Convert faster, talk about your capabilities instead of benefits*(49:53) Quick Hits: Casey's quick hitsSponsor:Pipeline Visionaries is brought to you by Qualified.com. Qualified helps you turn your website into a pipeline generation machine with PipelineAI. Engage and convert your most valuable website visitors with live chat, chatbots, meeting scheduling, intent data, and Piper, your AI SDR. Visit Qualified.com to learn more.Links:Connect with Ian on LinkedInConnect with Casey on LinkedIn Learn more about DoWhatWorksLearn more about Caspian Studios

 ClearBridge Investments' Jeff Schulze provide his insights on the US labor market—reviewing the latest job report and past payroll revision figures. And, he covers why his views about potential Fed rate cuts in 2025 have shifted.

Crypto News: SEC says certain liquid staking tokens are NOT securities, this bodes well for approval of staking in Ethereum ETFs this month. Coinbase BASE goes down, Brazil's lower house to hold hearing on creating national Bitcoin reserve.Show Sponsor -

Turn online alignment into an offline community — join us at TheWayFwrd.com to connect with like-minded people near you. It's the best way to support this podcast and the movement we're building together: https://thewayfwrd.com/join DPAK joins Alec for a conversation on coherence, creativity, and reclaiming sovereignty through sound. He shares how he stepped away from a path in conventional medicine to follow music as a tool for healing and alignment. They explore the relationship between frequency and wellbeing, the mindset behind mastering new skills, and how authentic expression becomes a signal of truth in a disoriented world. For more details, links, timestamps and resources mentioned in this episode, visit our website: https://thewayfwrd.com/content/ Resources and Links Website: www.dpakworld.comInstagram:https://www.instagram.com/dpak.world/ The Way Forward podcast is sponsored by: New Biology Clinic: Experience individually tailored terrain-based health services with virtual consults, practitioner livestreams, movement classes, and more. The New Biology Clinic's motivation is to make you healthy and keep you that way. Visit https://NewBiologyClinic.com and enter code TheWayForward for $50 off your activation fee. Members of The Way Forward get the full activation fee waived. Become a member of The Way Forward here: https://thewayfwrd.com/membership-sign-up/ ————————— RMDY Collective: Dedicated to making homeopathy accessible with high-quality remedies and hands-on training. Discover how this holistic approach supports natural healing and empowers you to take charge of your wellness.  Enroll in RMDY Academy at https://rmdyacademy.org/?bg_ref=MKho6KZowa Explore more at RMDY Collective at https://rmdycollective.org/?bg_ref=MKho6KZowa ————————— Medicamentum Authentica: Boost energy, mental clarity, and vitality with Authentica Shilajit™, a mineral-rich supplement trusted for holistic wellness. It supports stamina, focus, hormonal balance, and detoxification while promoting long-term health. Get 10% off with code WAYFORWARD at medauthentica.com/wayforward

Today on Moment of Zen, Erik Torenberg and Samo Burja explore how China's elite universities are creating a ruling class similar to America's, with student activism and credentialism reshaping both nations' power structures. Make sure to subscribe to Samo Burja's Bismarck Brief and the Live Players podcast to read analyses and briefs like this one: Bismarck Brief: ⁠https://brief.bismarckanalysis.com/⁠ Live Players: ⁠https://link.chtbl.com/liveplayers⁠ --

Send us a textIn this juicy new episode of Big Sexy Chat, Chrystal and Merf are back with updates, laughter, and deep dives into fat pleasure, power exchange, and the ways we signal our sexy truths to the world.

In our news wrap Wednesday, the U.S. Federal Reserve left interest rates unchanged for the fourth-straight time while officials indicated they expect to cut rates twice by the end of the year, the Supreme Court is reviving plans to store nuclear waste at sites in Texas and New Mexico and the FDA has approved the world's only twice-a-year injection for HIV prevention. PBS News is supported by - https://www.pbs.org/newshour/about/funders

The National Security Hour with Blanquita Cullum – “Operation Rising Lion” is trying to eliminate the nuclear sites/ threat posed by Iran. Fordow-Fordow Fuel Enrichment Plant — the largest site is mostly safe, as it is built deep within a mountain. Almost impenetrable, Fordow is enriched with 60% Uranium just below the level to make a nuclear bomb. Are bunker buster bombs on the horizon?

In this episode of The PDB Afternoon Bulletin:  First, it appears Iran may already be folding under the weight of Israel's heavy airstrikes, as reports emerge that the mullahs have quietly reached out to Oman and Qatar to mediate a ceasefire. Later in the show—after an intensive two day manhunt, authorities have apprehended 57-year-old Vance Boelter, the gunman accused of murdering a Minnesota state lawmaker and her husband, and seriously wounding two others. To listen to the show ad-free, become a premium member of The President's Daily Brief by visiting PDBPremium.com. Please remember to subscribe if you enjoyed this episode of The President's Daily Brief. YouTube: youtube.com/@presidentsdailybrief Birch Gold: Text PDB to 989898 and get your free info kit on gold Mando: Control Body Odor ANYWHERE with @shop.mando and get 20% off + free shipping with promo code PDB at shopmando.com! #mandopod Learn more about your ad choices. Visit megaphone.fm/adchoices

This week, we take a field trip to Google and report back about everything the company announced at its biggest show of the year, Google I/O. Then, we sit down with Google DeepMind's chief executive and co-founder, Demis Hassabis, to discuss what his A.I. lab is building, the future of education, and what life could look like in 2030.Guest:Demis Hassabis, co-founder and chief executive of Google DeepMindAdditional Reading:At Google I/O, everything is changing and normal and scary and chillGoogle Unveils A.I. Chatbot, Signaling a New Era for SearchGoogle DeepMind C.E.O. Demis Hassabis on the Path From Chatbots to A.G.I.We want to hear from you. Email us at hardfork@nytimes.com. Find “Hard Fork” on YouTube and TikTok. Unlock full access to New York Times podcasts and explore everything from politics to pop culture. Subscribe today at nytimes.com/podcasts or on Apple Podcasts and Spotify.