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"FAN MAIL - How does this episode resonate with you?" “Dialogues” is a series from the Global Health Matters podcast where we bring you interviews featuring fresh perspectives on global health issues. The goal of each Dialogues episode is to break through the echo chambers that exist in global health through in-depth, thoughtful conversations. In this episode of Dialogues, host Garry Aslanyan speaks with Peter Hotez, an internationally-recognized physician-scientist in neglected tropical diseases and vaccine development. In 2022, Hotez and his colleague Maria Elena Bottazzi were nominated for the Nobel Peace Prize for “their work to develop and distribute a low-cost COVID-19 vaccine to people of the world without patent limitation.” He is also one of the leading defenders of vaccines in the United States and the author of several books, including "Preventing the Next Pandemic," "The Deadly Rise of Anti-Science" and “Vaccines did not cause Rachel's autism.”Related episode documents, transcripts and other information can be found on our website.Subscribe to the Global Health Matters podcast newsletter. Follow @TDRnews on Twitter, TDR on LinkedIn and @ghm_podcast on Instagram for updates. Disclaimer: The views, information, or opinions expressed during the Global Health Matters podcast series are solely those of the individuals involved and do not necessarily represent those of TDR or the World Health Organization. All content © 2024 Global Health Matters.
The last great "out of Arica" movement of our ancestors swept out of the northeast of the continent 74,000 years ago. Archaeologist John Kappelman of the University of Texas brings us an update to this complex tale in the form of animal carcasses. We take a trip to Oxford to meet some of postgraduate researcher Ally Morton-Hayward's archive of preserved brains. Not only is Ally shining a light on these underappreciated brains, she is also using them to unlock a rich treasure-trove of information about our ancestors and how they were preserved.How do you develop and promote a vaccine against a widespread but neglected parasite? Maria Elena Bottazzi from Baylor College of Medicine is in India promoting their latest development in creating a hookworm vaccine that works against these life-limiting childhood parasites. And, is the Chandra X-Ray Observatory at risk? In a decision that has shocked astronomers, the functioning telescope is on the chopping block because of NASA budget cuts. We hear from Belinda Wilkes of Bristol University about Chandra's impressive history and why it should keep going. Presenter/producer: Roland Pease Researcher: Katie Tomsett Production co-ordinator: Jana Bennett-Holesworth(Image: Sunset in savannah of Africa. Credit: Anton Petrus via Getty Images)
Recorded at ASM Microbe 2023, Cesar has a conversation with Dr. Maria Elena Bottazzi about the role of minority women in science and discovery, the journey of Hispanic women in science and the current challenges posed by society to deliver science and global health equity. Guest: Dr. Maria Elena Bottazzi - Sr. Associate Dean of the National School of Tropical Medicine at Baylor College of Medicine, Distinguished Professor of Biology at Baylor University, Waco This episode is brought to you by the Antimicrobial Agents and Chemotherapy journal available at aac.asm.org. If you plan to publish in AAC, ASM Members get up to 50% off publishing fees. Visit asm.org/membership to sign up. Visit journals.asm.org/journal/aac to browse issues and/or submit a manuscript.
Dr. Kelly Zúñiga the director of the Holocaust Museum of Houston, joins us to talk about the upcoming LBJ Moral Courage Award Dinner honoring Dr. Peter Hotez and Dr. Maria Elena Bottazzi 2022 Nobel Peace Prize Nominees for their efforts in helping develop an affordable, easy to produce COVID-19 vaccine. In this segment, Kelly talks about the museum's recent expansion, the trait the organization looks for in selecting honorees, and provides a sneak peak into this year's dinner. Additionally, Kelly reveals how her event so inspired a Broadway legend, who performed at the event, that she donated her fee back to the museum.
Which Houstonians delighted us this year? And which ones deserve coal in their stockings? Texas Monthly staff writer Michael Hardy and host Lisa Gray offer Santa their guidance. Naughty List: Mattress Mack, for his open letter to Lina Hidalgo. Isabel Longoria, for botching the 2022 primary. Vidal Martinez. for falsely accusing Alex Mealer's grandfather as a Castro supporter. Ted Cruz, because in April, he accused Supreme Court nominee Ketanji Brown Jackson of supporting critical race theory. Houston Texans, Worst team in the NFL. 1-12-1. Officially the worst Houston Texans team of all time. Nice List: The Houston Astros, for winning the world series emphatically! Peter Hotez and Maria Elena Bottazzi, for developing an affordable vaccine for the global south. Mo Amer, for his Netflix series that centred Houston as a principal character. Lizzo, For showing love to her hometown of Alief and having a phenomenal year. Dusty Baker, For getting done with the Astros and his infectious aura. Rich and Nancy Kinder, for donating millions to elevate Houston. Checkout our daily newsletter, Hey Houston for some banger end of the year content! Follow us on Instagram and Twitter to usher in the Holidays with us! Leave us a voicemail or text at +1 713-489-6972 to tell us your thoughts on 2022 for Houston! Learn more about your ad choices. Visit megaphone.fm/adchoices
How to stay healthy during the holidays with infectious disease expert, Peter Hotez, MD, PhD—who breaks down the "septo-demic" of: coronavirus, influenza, respiratory syncytial virus (RSV), metapneumovirus (HMPV), parainfluenza viruses (HPIVs), rhinovirus and numacocle pathogens. Dr. Hotez also shares details about fighting vaccine disinformation and his new book: “The Deadly Rise of Anti-Science: How Health Freedom Propaganda Endangers the World.” Dr. Hotez is dean of the National School of Tropical Medicine at Baylor College of Medicine and co-director of the Texas Children's Hospital Center for Vaccine Development in Houston. He and his science partner, Maria Elena Bottazzi, PhD, have been nominated for a Nobel Peace Prize. American Medical Association CXO Todd Unger hosts.
What is an open source vaccine? How are vaccine and beer production similar? Are D.I.Y. vaccine starters kits the best strategy to vaccinate the world? Dr. Maria Elena Bottazzi is an internationally recognized tropical and emerging disease vaccinologist, global health advocate and co-creator of a patent-free, open science COVID-19 vaccine technology that led to the development of Corbevax, a COVID-19 vaccine for the world. She pioneers and leads innovative partnerships for the advancement of a robust vaccine development portfolio tackling diseases that disproportionately affect the world's poorest populations, making significant contributions to catalyze policies and disseminate science information to reach a diverse set of audiences. In 2022, alongside vaccine researcher Peter Hotez, she was nominated by Congresswoman Lizzie Fletcher of Texas for the Nobel Peace Prize. Follow Maria Elena Bottazzi: Twitter | LinkedIn Episode website link: https://mailchi.mp/designlabpod/mariaelenabottazzi More episode sources & links Sign-up for Design Lab Podcast's Newsletter Newsletter Archive Follow @DesignLabPod on Twitter Instagram and LinkedIn Follow @BonKu on Twitter & Instagram Check out the Health Design Lab Production by Robert Pugliese Cover Design by Eden Lew Theme song by Emmanuel Houston
Dr. Peter J. Hotez, M.D., Ph.D. (https://peterhotez.org/), is Dean of the National School of Tropical Medicine and Professor of Pediatrics and Molecular Virology and Microbiology at Baylor College of Medicine where he is also Chief of the Section of Pediatric Tropical Medicine and the Texas Children's Hospital Endowed Chair of Tropical Pediatrics . Dr. Hotez is also Rice University's Baker Institute fellow in disease and poverty and Co-Director of Parasites Without Borders (https://parasiteswithoutborders.com/), a global nonprofit organization with a focus on those suffering from parasitic diseases in subtropical environments. Dr. Hotez is an internationally recognized physician-scientist with expertise in neglected tropical diseases and vaccine development. He leads the only product development partnership for developing new vaccines for hookworm, schistosomiasis and Chagas disease, and is just coming off a major win for emergency use approval of his team's Corbevax protein sub-unit COVID-19 vaccine, of which he, and previous guest to the show, Dr. Maria Elena Bottazzi, were recently nominated for a Nobel Prize. Dr. Hotez is the author of more than 400 original papers, as well as the books Forgotten People, Forgotten Diseases - The Neglected Tropical Diseases and Their Impact on Global Health and Development, Blue Marble Health - An Innovative Plan to Fight Diseases of the Poor amid Wealth, Vaccines Did Not Cause Rachel's Autism: My Journey as a Vaccine Scientist, Pediatrician, and Autism Dad, and Preventing the Next Pandemic: Vaccine Diplomacy in a Time of Anti-science. Dr. Hotez previously served as president of the American Society of Tropical Medicine and Hygiene, the Sabin Vaccine Institute and as founding editor-in-chief of PLoS Neglected Tropical Diseases. He is an elected member of the Institute of Medicine (IOM) of the National Academy of Sciences. In 2011, he was awarded the Abraham Horwitz Award for Excellence in Leadership in Inter-American Health by the Pan American Health Organization of the World Health Organization. In 2015, the White House and U.S. State Department selected Dr. Hotez as a United States science envoy. Dr. Hotez obtained his undergraduate degree in molecular biophysics from Yale University (Phi Beta Kappa), followed by a Ph.D. in biochemical parasitology from Rockefeller University, and an M.D. from Weill Cornell Medical College.
Today, in episode 492, our expert Infectious Disease Doctor and Community Health Specialist discuss what you need to know about Public Health. We begin by celebrating women in science by highlighting two women and their accomplishments in the field of public health: Nina Shah and Maria Elena Bottazzi. We also talk about the importance of addressing the public with empathy and compassion. As always, join us for all the Public Health information you need, explained clearly by our health experts. Website: NoiseFilter - Complex health topics explained simply (noisefiltershow.com) Animations: NoiseFilter - YouTube Instagram: NoiseFilter (@noisefiltershow) • Instagram photos and videos Facebook: NoiseFilter Show | Facebook TikTok: https://www.tiktok.com/@noisefiltershow --- Send in a voice message: https://anchor.fm/noisefilter/message
New Device Helps People With Paralysis Walk Again Spinal cord injuries are notoriously difficult to treat, especially for those who have been paralyzed for several years. Now, researchers have developed a new implant that is able to reverse paralysis in patients with complete spinal cord injuries. The device uses specially designed electrodes, which bring the brain back into communication with the patient's lower body. The findings were recently published in the academic journal Nature Medicine. Ira talks with the study's co-authors, Jocelyne Bloch, a neurosurgeon at Lausanne University Hospital, and Grégoire Courtine, professor of neuroscience at the Swiss Federal Institute of Technology, based in Lausanne, Switzerland. Could Protein-Based Vaccines Help Close The Global Vaccination Gap? A new generation of COVID-19 vaccines are being developed and distributed around the world. They're called recombinant-protein vaccines. But the tech is actually not at all new. In fact, It's been used to produce hepatitis C and pertussis vaccines for decades. These protein-based vaccines have an edge over mRNA vaccines in a few ways. They're just as effective, cheaper and simpler to manufacture, and easier to distribute. So why, two years into the pandemic, have they just started gaining traction? And can recombinant-protein vaccines help close the global coronavirus vaccination gap? Ira discusses these developments with Dr. Maria Elena Bottazzi, the co-creator of Corbevax, a patent-free protein-based vaccine, for which she was recently nominated for the Nobel Peace Prize. She's also the co-director of the Center for Vaccine Development at Texas Children's Hospital, and a professor at the Baylor College of Medicine, based in Houston, Texas. How Cuba Developed Five COVID-19 Vaccines Cuba was able to quickly produce five coronavirus vaccines, thanks to the island's robust biotech industry. For decades, Cuba has produced its own home-grown vaccines and distributed them to neighboring countries. But sanctions and political dynamics have complicated Cuba's ability to distribute their COVID-19 vaccines with the world. Ira talks with Helen Yaffe, senior lecturer of economic and social history at Glasgow University, and author of We Are Cuba! How a Revolutionary People Have Survived in a Post-Soviet World. Fish Make More Noise Than You Think One of the most famous films of undersea explorer Jacques Cousteau was titled The Silent World. But when you actually stop and listen to the fishes, the world beneath the waves is a surprisingly noisy place. In a recent study published in the journal Ichthyology & Herpetology, researchers report that as many of two-thirds of the ray-finned fish families either are known to make sounds, or at least have the physical capability to do so. Some fish use specialized muscles around their buoyancy-modulating swim bladders to make noise. Others might blow bubbles out their mouths, or, in the case of herring, out their rear ends, producing “fish farts.” Still other species use ridges on their bodies to make noises similar to the way crickets do, grind their teeth, or snap a tendon to sound off. The noises serve a variety of purposes, from calling for a mate to warning off an adversary. Aaron Rice, principal ecologist in the K. Lisa Yang Center for Conservation Bioacoustics at the Cornell Lab of Ornithology in Ithaca, walks Ira through some of the unusual sounds produced by known fish around the world—and some mystery noises that they know are produced by fish, but have yet to identify.
Leigh Nash is back on the show! She is best known to wider audience for being a lead singer of Sixpence None the Richer, and their 1990s hit 'Kiss Me' from the movie 'She's All That.' Leigh has reemerged after a few years' recording break with a new album called 'The Tide' which will come out in two parts. Vol.1 is already out and features a phenomenal song 'God Gave me Horses' that I've been listening on repeat. We talk about Leigh's upcoming US tour, where her mom will accompany her for the first time. She also shares who her favorite new artists are and her take on the Spotify-Joe Rogan-Neil Young-Joni Mitchell situation. We had a wonderful conversation and lots of laughs, so sit back and enjoy! Watch the episode at https://www.lonestarplate.show/episodes/leigh-nash-new-album “Connection with the audience feels like an extension of my body. If I don't have it, it's like something's slowly being drained out of me.” - Leigh Nash This episode is dedicated to Leigh's grandma Ruby Woolley that passed away this year at the age of 98. Time stamps: 0:00 - Introducing our guest Leigh Nash. 3:55 - Local Texas Movers and Shakers: Yolanda Nagy from Eatin' and Sippin' Locally 5:15 - Commenting on episode #200 with Dr. Maria Elena Bottazzi and Dr. Peter Hotez 9:50 - Leigh announcing the start of her 2022 tour. 14:15 - Why it makes Leigh's mom sad when she sees her daughter performing. 18:39 - Who the collaborators on The Tide Vol. 1 are and when Vol. 2 comes out. 20:50 - The story behind Leigh's new single “God Gave me Horses” 25:11 - The importance for Leigh to have her house in order in order to work creatively. 31:30 - Whether I'd want to get back into the food business. 34:30 - Leigh's take on the Spotify situation and musicians pulling their music off the platform. 45:19 - Where Leigh is going to tour in 2022. 50:13 - What music Leigh currently listens to. 57:50 - Recommending ‘Jackass: The Movie.' Resources: - Stream and buy Leigh's new album ‘The Tide' https://leighnash.ffm.to/thetidevol1 - Jackass Forever (2022) https://www.jackassmovie.com/ - Giving Voice to Farmers' Markets with Yolanda Nagy https://youtu.be/lm4QfFKa76M - Texas Real Food https://texasrealfood.com Connect with Leigh Nash: - Website https://www.leighnash.net/ - Instagram https://www.instagram.com/leighbirdnash/ - Facebook https://www.facebook.com/leigh.nash.music/ Connect with Patrick Scott Armstrong: - IG: @patrickscottarmstrong - https://www.facebook.com/patrickscottvideos/ - patrick@texasrealfood.com Follow The Lone Star Plate: - Follow us on Twitter: @lonestarplateTX - Follow us on Instagram: @lonestarplateTX - Like us on Facebook: https://www.facebook.com/LoneStarPlateTX - Follow us on TikTok: @lonestarplate - More From The Lone Star Plate: https://lonestarplate.show - Texas Real Food: https://www.texasrealfood.com
CORBEVAX is a patent-free, low-cost coronavirus vaccine created in Houston, which is being used across the world to vaccinate low income countries. I'm joined by Dr. Peter Hotez and Dr. Maria Elena Bottazzi who created the vaccine here in Texas and are working on getting it distributed. They've just been nominated for the Nobel Peace Prize and have come to talk to us about Corbevax vaccine, how it's changing the world, and the lives they're saving. Watch the full episode at https://lonestarplate.show/episodes/corbevax “If we hadn't come to Texas, I can promise you there'd be no Covid vaccine, and that's a side of Texas that people don't hear about.” - Dr. Peter Hotez Time Stamps:00:00 - Introducing our guests and their new vaccine Corbevax. 08:49 - What Corbevax is and how it's different from a mRNA vaccine. 12:39 - Why it's important to create a vaccine that can be developed anywhere in the world. 14:26 - How the starter kit for the Corbevax vaccine is distributed so that countries can develop the vaccine themselves. 20:15 - What it feels like to be nominated for the Nobel Peace Prize. 21:44 - Why making vaccines is different from making drugs and why the manufacturing of Corbevax is different from other Covid vaccines. 24:36 - The role that academics and universities have in vaccine development. 26:56 - Why Dr. Bottazzi and Dr. Hotez came to Texas to develop this vaccine. 30:20 - How long mRNA vaccines have been around and the advantages and disadvantages they have. 32:38 - The amount of fear some people have towards mRNA vaccines. 33:39 - Why there will always be multiple different technologies behind vaccines. 36:58 - The problem with Operation Warp Speed. 38:14 - What misinformation means. 39:33 - Why we need the booster shot of the Covid vaccine. 41:20 - Why you can still get Covid even if you're vaccinated. 43:16 - Why it's important to get the vaccine even if you are young and healthy. 44:40 - Why non-vaccinated people put vaccinated people at risk. 46:17 - The myth of doctors overprescribing Covid as the cause of death. 48:47 - The impact masks have and when we'll be able to stop wearing them. 52:13 - The issues with shaming non-vaccinated people. 55:50 - Our favorite restaurants in Houston. Resources: - CORBEVAX https://wikipedia.org/wiki/Corbevax - DCVMN http://www.dcvmn.org/ - Tito's Vodka https://www.titosvodka.com - The Kleberg Foundation https://www.klebergfoundation.org/ - The Anderson Foundation https://www.theandersonfoundation.org/ - TAMEST https://tamest.org/ - Operation Warp Speed https://en.wikipedia.org/wiki/Operation_Warp_Speed - Truth BBQ https://www.truthbbq.com/ - Hugo's https://www.hugosrestaurant.net/ - Cafe Brazil https://www.cafebrazil.com/menu/ Connect with Dr. Peter Hotez: - LinkedIn https://www.linkedin.com/in/peter-hotez-md-phd-14286572 - Website https://peterhotez.org/ Connect with Dr. Maria Elena Bottazzi: LinkedIn https://www.linkedin.com/in/maria-elena-bottazzi-58909831 - Twitter https://twitter.com/mebottazzi Connect with Patrick Scott Armstrong: - IG: @patrickscottarmstrong - https://www.facebook.com/patrickscottvideos/ - patrick@texasrealfood.com Follow The Lone Star Plate: - Follow us on Twitter: @lonestarplateTX - Follow us on Instagram: @lonestarplateTX - Like us on Facebook: https://www.facebook.com/LoneStarPlateTX - Follow us on TikTok: @lonestarplate - More From The Lone Star Plate: https://thelonestarplate.com - Texas Real Food: https://www.texasrealfood.com Love garlic? You'll get addicted to Mamo's Garlic Sauce! https://youtu.be/zi_-l6rjpRQ
Dr. Peter Hotez is co-director of the Center for Vaccine Development at Texas Children's Hospital and Dean of the National School of Tropical Medicine at Baylor College of Medicine. Dr. Peter J. Hotez, MD, PhD and his partner Dr. Maria Elena Bottazzi were recently nominated for a Nobel Peace Prize for their work to develop a low-cost COVID-19 vaccine. Dr. Hotez is involved in the development of CORBEVAX, which has been dubbed “the world's vaccine.” It uses traditional recombinant protein based technology that will enable its production at large scales, making it widely accessible to inoculate the global population. Find more from Dr. Hotez at: https://peterhotez.org https://twitter.com/peterhotez Read Dr. Peter Hotez's book “Preventing the Next Pandemic: Valid Diplomacy in a Time of Anti-science.” Ask Dr. Drew is produced by Kaleb Nation ( https://kalebnation.com) and Susan Pinsky (https://twitter.com/FirstLadyOfLove). SPONSORS • REFRAME – Since the beginning of the pandemic, nearly 1 in 5 Americans has reported consuming an unhealthy amount of alcohol, but only 10% of them are actually getting the help they need. Reframe is a neuroscience-based smartphone app that helps users cut back or quit drinking alcohol. Use the code DRDREW for 25% off your first month or annual subscription at https://drdrew.com/reframe • BLUE MICS – After more than 30 years in broadcasting, Dr. Drew's iconic voice has reached pristine clarity through Blue Microphones. But you don't need a fancy studio to sound great with Blue's lineup: ranging from high-quality USB mics like the Yeti, to studio-grade XLR mics like Dr. Drew's Blueberry. Find your best sound at https://drdrew.com/blue • HYDRALYTE – “In my opinion, the best oral rehydration product on the market.” Dr. Drew recommends Hydralyte's easy-to-use packets of fast-absorbing electrolytes. Learn more about Hydralyte and use DRDREW25 at checkout for a special discount at https://drdrew.com/hydralyte • ELGATO – Every week, Dr. Drew broadcasts live shows from his home studio under soft, clean lighting from Elgato's Key Lights. From the control room, the producers manage Dr. Drew's streams with a Stream Deck XL, and ingest HD video with a Camlink 4K. Add a professional touch to your streams or Zoom calls with Elgato. See how Elgato's lights transformed Dr. Drew's set: https://drdrew.com/sponsors/elgato/ THE SHOW: For over 30 years, Dr. Drew Pinsky has taken calls from all corners of the globe, answering thousands of questions from teens and young adults. To millions, he is a beacon of truth, integrity, fairness, and common sense. Now, after decades of hosting Loveline and multiple hit TV shows – including Celebrity Rehab, Teen Mom OG, Lifechangers, and more – Dr. Drew is opening his phone lines to the world by streaming LIVE from his home studio in California. On Ask Dr. Drew, no question is too extreme or embarrassing because the Dr. has heard it all. Don't hold in your deepest, darkest questions any longer. Ask Dr. Drew and get real answers today. This show is not a substitute for medical advice, diagnosis, or treatment. All information exchanged during participation in this program, including interactions with DrDrew.com and any affiliated websites, are intended for educational and/or entertainment purposes only.
Texas-based scientists Maria Elena Bottazzi and Peter Hotez won't make a cent off the vaccine they developed — and they don't want to. Dubbed "the world's COVID-19 vaccine," Corbevax is cheap and relatively easy to manufacture, and there's no patent on it. After multiple hurdles in the team's efforts to fund and develop the jab, Corbevax was recently approved for emergency use in India. Today, we're speaking to Bottazzi and Hotez about the story behind Corbevax, what the skeptics have to say, and why they believe their shot can be a powerful tool in the fight for vaccine equity.
Dr. Peter Hotez has become one of the faces of the pandemic. The bow-tied Texas scientist has been all over radio and television — and on this podcast, too — explaining viruses generally and COVID-19 specifically. Now Hotez and his partner, PhD scientist Maria Elena Bottazzi, have developed a vaccine that would be cheap and easy to produce.
President Biden is set to make a speech about voting rights in Atlanta Tuesday. James Woodall, former president of the NAACP in Georgia, explains why he signed a letter urging more action from the White House on voting rights. And, CORBEVAX is a low-cost, patent-free vaccine was developed by Dr. Peter Hotez and his colleague Maria Elena Bottazzi. Hotez discusses the importance of vaccinating the world.
Now being produced in India CORBEVAX is grown in yeast in a similar way to several other widely available vaccines. The technology used to make it is far simpler and much more readily available than that used to produce mRNA vaccines. In theory, CORBEVAX could be produced cheaply in large quantities and go a long way to addressing the problems of Covid19 vaccine availability globally. It was developed by a team from Baylor College of Medicine in Texas including Maria Elena Bottazzi. Antibiotic-resistant superbugs are thought to have emerged in repose to the use of antibiotics, however, the discovery of a superbug living on the skin of hedgehogs has challenged this view. The superbug is thought to have been living with hedgehogs long before antibiotics were discovered. Jesper and Anders Larsen at the Danish State Serum Institute in Copenhagen explain. Modifying viruses, using them to infect or kill pest organisms is an attractive proposition. However, there are concerns over what might happen when they are released, particularly over their ability to mutate and evolve says Filippa Lentzos from Kings College Department of Global Health and Social Medicine in London. And The Royal Botanical Gardens at Kew have released the names of over 200 new species of plants and fungi discovered last year. Mycologist Tuula Niskanen and botanist Martin Cheek tell us more. Also... “I'm bored!” We can all relate to the uncomfortable - and at times unbearable - feeling of boredom. But what is it? Why does it happen? And could this frustrating, thumb-twiddling experience actually serve some evolutionary purpose? CrowdScience listener Brian started wondering this over a particularly uninspiring bowl of washing up, and it's ended with Marnie Chesterton going on a blessedly un-boring tour through the science and psychology of tedium. She finds out why some people are more affected than others, why boredom is the key to discovery and innovation, and how we can all start improving our lives by embracing those mind-numbing moments. (Image: Getty Images)
Now being produced in India CORBEVAX is grown in yeast in a similar way to several other widely available vaccines. The technology used to make it is far simpler and much more readily available than that used to produce mRNA vaccines. In theory, CORBEVAX could be produced cheaply in large quantities and go a long way to addressing the problems of Covid19 vaccine availability globally. It was developed by a team from Baylor College of Medicine in Texas including Maria Elena Bottazzi. Antibiotic-resistant superbugs are thought to have emerged in repose to the use of antibiotics, however, the discovery of a superbug living on the skin of hedgehogs has challenged this view. The superbug is thought to have been living with hedgehogs long before antibiotics were discovered. Jesper and Anders Larsen at the Danish State Serum Institute in Copenhagen explain. Modifying viruses, using them to infect or kill pest organisms is an attractive proposition. However, there are concerns over what might happen when they are released, particularly over their ability to mutate and evolve says Filippa Lentzos from Kings College Department of Global Health and Social Medicine in London. And The Royal Botanical Gardens at Kew have released the names of over 200 new species of plants and fungi discovered last year. Mycologist Tuula Niskanen and botanist Martin Cheek tell us more. (Image: Getty Images) Presenter: Roland Pease Producer: Julian Siddle
India has approved the use of a patent-free Covid-19 vaccine, which was developed at Baylor College of Medicine in the US. We speak to Maria Elena Bottazzi, who tell us her team developed Corbevax with the aim of expanding access to essential healthcare for people in poorer countries. Plus, the United Nations says food prices increased by 28% in 2021. Abdolreza Abbassian from the UN's Food and Agriculture Organization tells us those struggling financially will be hit the hardest by the rise. With the authorities in the United States still attempting to track down everybody involved in the January 6th invasion of the US Capitol, Anjana Susarla of Michigan State University tells us why facial recognition technology is an increasingly important tool in the search. And at CES 2022, we catch up with Remane CEO Ariel Lee, who tells us about her company's “data-driven haircare solutions”.
Town Square with Ernie Manouse airs at 3 p.m. CT. Tune in on 88.7FM, listen online or subscribe to the podcast. Join the discussion at 888-486-9677, questions@townsquaretalk.org or @townsquaretalk. Today is another milestone in the COVID-19 pandemic, where the U.S. has passed 800,000 deaths due to the virus. However, it seems as though many have become numb to such numbers. Amidst reports of the fast-spreading omicron variant, Houston hospitals have been developing a new, easy-to-make vaccine that will cover the gaps in other counties that are working to inoculate against the virus. In this episode of Town Square, we talk with Dr. Maria Elena Bottazzi, Co-Director of the Texas Children's Hospital Center for Vaccine Development, about the vaccine she's working on with her Co-Director, Dr. Peter Jay Hotez. Along with the latest COVID headlines, we answer your questions about the effectiveness of vaccines against omicron and provide an update on the virus, vaccines, and variants. Guests: Dr. Maria Elena Bottazzi Associate Dean of the National School of Tropical Medicine at Baylor College of Medicine Co-Director of the Texas Children's Hospital Center for Vaccine Development Dr. Katelyn Jetelina Epidemiologist with UTHealth School of Public Health Author of the blog Your Local Epidemiologist Town Square with Ernie Manouse is a gathering space for the community to come together and discuss the day's most important and pressing issues. Audio from today's show will be available after 5 p.m. CT. We also offer a free podcast here, on iTunes, and other apps.
Nearly two years after Covid-19 was first detected in Wuhan, the world is still very much in a pandemic. The toughest phase may behind us, but we are still faced with the possibility of new variants of concern, waning immunity and vaccine evasion. As first-generation vaccines start to show their weaknesses, next-generation vaccines are becoming more and more important. While hundreds of vaccines are in the pipeline, there are a few frontrunners and other interesting candidates that might be meaningful additions to our Covid vaccine armamentarium. Experts discuss the current status of a number of protein-based vaccines including candidates from Novavax, Vaxine, Clover, GSK/Sanofi and others. DNA vaccines are also still an attraction with the first authorization for Zydus Cadila in India. Other mRNA vaccines might offer meaningful differentiation, while vaccines targeting the S and N protein might also have greater importance when it comes to tackling future variants. While nasal and oral vaccines seem appealing for the prevention of infection and transmission, they also have some inevitable hurdles to overcome and are still a long way off materializing. Experts discuss future manufacturing hurdles that will require greater global collaboration to achieve future vaccine production and distribution goals. Finally, experts discuss the current global status so far and forecasts for exiting the pandemic state and entering a livable endemic. Expert Guests: -- Reynald Castaneda is the Clinical Trials Editor of GlobalData Media in London, covering drug development for investors and the pharmaceutical industry. -- Dr Maria Elena Bottazzi is the Associate Dean, National School of Tropical Medicine and Professor of Pediatrics (Tropical Medicine) and Molecular Virology and Microbiology at Baylor College of Medicine, Texas, US. She is a leading expert in vaccine development and tropical diseaes. -- Dr Deborah Fuller is a Professor of Microbiology at The University of Washington School of Medicine. A veteran vaccinologist and researcher, she has been working on vaccine development for the last 30 years with specific research around DNA and RNA technologies. -- Dr Shabir Madhi is Dean of the Faculty of Health Sciences and Professor of Vaccinology at the University of the Witwatersrand, Johannesburg, South Africa. He is also the co-founder of the African Leadership Initiative for Vaccinology Expertise (ALIVE). -- Dr Nikolai Petrovsky is Professor of Medicine, Flinders University, Adelaide, Australia and vice-president and secretary-general of the International Immunomics Society. He is the founder of vaccine biotech, Vaxine, which has a protein based vaccine for Covid-19 in its pipeline. -- Dr Monica Gandhi is Professor of Medicine and Associate Division Chief (Clinical Operations/Education) of the Division of HIV, Infectious Diseases, and Global Medicine at University California San Francisco/San Francisco General Hospital. -- Dr Prashant Yadav is a Senior Fellow at the Center for Global Development and Affiliate Professor of Technology and Operations Management at INSEAD. Yadav has with governments and global organizations to improve medical product supply chains. Previous roles include Strategy Leader-Supply Chain at the Bill & Melinda Gates Foundation and Chair of the Market Dynamics Advisory Group of the Global Fund. -- Dr. Nadia Sam-Agudu is Associate Professor of Pediatrics (Immunology/Infectious Diseases) at the University of Maryland School of Medicine and Senior Technical Advisor at the Institute of Human Virology Nigeria. She conducts public health and implementation research in maternal and child health, with a focus on HIV and other major infectious diseases in African countries.
Vaccination in children has fueled a global expert debate specifically around the risk benefit consideration that some may find acceptable and others may find questionable. While children were largely protected from the virus early on in the pandemic, we've come to a point where children are getting sick, some of them severely ill and dying. Experts discuss the changing risks of Covid in kids and how the benefits of vaccination in kids measure up versus potential adverse events. We first look at inactivated vaccines, which are now the most used vaccines in children (as young as 2 years of age) and we take a special deep dive into Chile's rationale for its large scale vaccination drive to get kids back into school. mRNA vaccines are also starting to get rolled out with Pfizer just receiving a US authorization in kids aged 5-11, and experts discuss the risk benefits and greater unknowns of this new technology, particularly around the nuance of dosing, Experts discuss the overall rationale for vaccination when looking at efficacy, safety and potential mechanistic concerns. Vaccinating kids and its overall impact on this pandemic remains debated, although perhaps not in Africa, where children may be the most at need of vaccination to reach global herd immunity, yet stand to be at the end of the queue. Meanwhile, as the issue around pregnancy continues to generate vaccine hesitancy, experts discuss new available data that speaks to the the risk/benefit profile in pregnant women and women wanting to conceive. Expert Guests -- Dr Miguel O'Ryan is Professor of Microbiology and Mycology, Faculty of Medicine at the University of Chile, where he is also Director of International Affairs. His research focuses on molecular and clinical aspects of enteric disease, pediatric vaccines and infection of the immunocompromised host. -- Dr. Nadia Sam-Agudu is Associate Professor of Pediatrics (Immunology/Infectious Diseases) at the University of Maryland School of Medicine, and Senior Technical Advisor at the Institute of Human Virology Nigeria. She conducts public health and implementation research in maternal and child health, with a focus on HIV and other major infectious diseases in African countries. -- Dr Nikolai Petrovsky is Professor of Medicine, Flinders University, Adelaide, Australia and vice-president and secretary-general of the International Immunomics Society. He is the founder of vaccine biotech, Vaxine, which has a protein based vaccine for Covid-19 in its pipeline. -- Dr Maria Elena Bottazzi is the Associate Dean, National School of Tropical Medicine and Professor of Pediatrics (Tropical Medicine) and Molecular Virology and Microbiology at Baylor College of Medicine, Texas, US. She is a leading expert in the field of vaccine development and tropical diseases. -- Dr Deborah Fuller is a Professor of Microbiology at The University of Washington School of Medicine. A veteran vaccinologist and researcher, she has been working on vaccine development for the last 30 years with specific research around DNA and RNA technologies.
With around 7 billion doses administered, the vaccines have largely been proven safe, but there are still major concerns around rare serious side-effects and long term safety unknowns. Experts discuss how safety events have been picked up via public reporting systems -- which have been both a help and a hindrance for the safety discussion -- and how they are being further analyzed. Experts breakdown real world data and the occurrence of rare serious adverse events including VITT (with the adenoviral vector vaccines) and myocarditis (with the mRNA vaccines). While the newer modalities have led to a few surprise fatalities, the inactivated viral vaccines remain clear of fatal serious events and experts discuss what risk ratio is generally acceptable in a deadly pandemic. Experts also discuss extreme safety alarm being perpetuated by social media, particularly the claim that vaccines are killing more people than they are saving. They stress the need for better public communication and education, whilst it is important to vet public sources that may be overdramatizing certain risks by promoting flawed analyses. Expert Guests: -- Dr Jeffrey Morris is Professor of Biostatistics and Director, Biostatistics Division at the University of Pennsylvania, US. His research focuses on developing quantitative methods to extract knowledge from biomedical big data and he set up a blog dedicated to issues concerning the Covid-19 pandemic. -- Dr Nikolai Petrovsky is Professor of Medicine, Flinders University, Adelaide, Australia and vice-president and secretary-general of the International Immunomics Society. He is the founder of vaccine biotech, Vaxine, which has a protein based vaccine for Covid-19 in its pipeline. -- Dr Maria Elena Bottazzi is the Associate Dean, National School of Tropical Medicine and Professor of Pediatrics (Tropical Medicine) and Molecular Virology and Microbiology at Baylor College of Medicine, Texas, US. She is a leading expert in the field of vaccine development and tropical diseases. -- Dr Miguel O'Ryan is Professor of Microbiology and Mycology, Faculty of Medicine at the University of Chile, where is also Director of International Affairs. His research focuses on molecular and clinical aspects of enteric disease, pediatric vaccines and infection of the immunocompromised host.
Since the last episode in February, a lot has happened with the vaccination rollout -- so we're back for a few more episodes. But we've changed our name from The CoVax Files to The Vax Files, which was was done mainly to avoid any confusion with GAVI/WHO's COVAX facility and also to maintain our independence from any official organization. As we approach the end of 2021 and almost 7 billion administered vaccine doses, we now have a good chunk of real world effectiveness data available. During this episode, experts walk us through some important datasets that can speak to how the vaccines have been working, with particular nuances around the emergence of the highly transmissible Delta variant. Experts take a deep dive into real world evidence data in different countries to elucidate overall protection, antibody waning, protection against severe disease and death as well as the likelihood of transmission when vaccinated. Finally, experts discuss the dangers of misinterpreting headline or summary data, which has been a regular occurrence in the media and social media during this pandemic. Expert Guests: -- Dr Jeffrey Morris is Professor of Biostatistics and Director, Biostatistics Division at the University of Pennsylvania, US. His research focuses on developing quantitative methods to extract knowledge from biomedical big data and he set up a blog dedicated to issues concerning the Covid-19 pandemic. -- Dr Nikolai Petrovsky is Professor of Medicine, Flinders University, Adelaide, Australia and vice-president and secretary-general of the International Immunomics Society. He is the founder of vaccine biotech, Vaxine, which has a protein based vaccine for Covid-19 in its pipeline. -- Dr Maria Elena Bottazzi is the Associate Dean, National School of Tropical Medicine and Professor of Pediatrics (Tropical Medicine) and Molecular Virology and Microbiology at Baylor College of Medicine, Texas, US. She is a leading expert in the field of vaccine development and tropical diseases. -- Dr Andrew Read is Professor of Biology and Entomology at PennState University, US. His research specializes in the ecology and evolutionary genetics of infectious disease, which includes the impact of vaccination on virus evolution.
Dr. Maria Elena Bottazzi is Distinguished Professor of Biology, Associate Dean of the National School of Tropical Medicine, and Professor in the Departments of Pediatrics, Molecular Virology and Microbiology, Integrative Molecular and Biomedical Sciences, and Translational Biology and Molecular Medicine, at Baylor College of Medicine. Dr. Bottazzi is also Co-Director, Texas Children's Hospital Center for Vaccine Development, Adjunct Professor, Department of Bioengineering, Rice University, and Editor-in-Chief, Current Tropical Medicine Reports. Dr. Botazzi has a degree in microbiology from Universidad Nacional Autónoma de Honduras, a PhD from University Of Florida, did a Post-Doctoral Fellowship at University Of Pennsylvania and at University Of Miami Hospital And Clinics, and a Fellowship at American Association for the Advancement of Science Leshner Leadership Institute. Dr. Botazzi is involved in a range of activities related to the development of novel vaccines and adjuvants for neglected tropical diseases (Chagas Disease, Leishmaniasis, Human Hookworm Vaccine, Schistosomiasis Vaccine), as well as extensive work on Covid vaccines.
Many of us will take a vaccine without thinking twice about it. But how are they developed, how do they even work, and how are they tested for safety? Press play to learn: What happens when proteins and aluminum-containing adjuvants are combined in the development of vaccines Why most vaccines are injected rather than inhaled or consumed orally, and what the future of vaccine delivery might look like How vaccines are tested for safety and efficacy Maria Elena Bottazzi is associate dean at the National School of Tropical Medicine at Baylor College of Medicine in Texas, and vaccine scientist who specializes in tropical, infectious, and emerging diseases. She explains conventional versus new technologies for vaccine development, like RNA technology platforms, and where the vaccine for the current virus situation lands in this regard. She dives into the science behind vaccine engineering, giving listeners an inside look at this technical and extremely relevant area of research and development. Bottazzi also discusses the testing and evaluation methods for safety, quality, and efficaciousness of various vaccines, including what are called controlled human challenge studies. Tune in to learn more and visit https://www.bcm.edu/education/national-school-of-tropical-medicine and https://www.bcm.edu/departments/pediatrics/sections-divisions-centers/tropical-medicine. Episode also available on Apple Podcasts: apple.co/30PvU9C
On this episode of HAR On The Move, we were joined again by Dr. Maria Elena Bottazzi with Baylor College of Medicine and Texas Children's Hospital, who shared everything we need to know about the Covid-19 vaccine for children and adults. Get Social With HAR! Are you an HAR MLS Platinum Subscriber? Join our Facebook Group! Click to join. Follow us on Facebook, Twitter, Instagram, YouTube and LinkedIn Get Social with the Hosts! Cristina- Twitter and Instagram David- Twitter