Podcasts about boston children

Enid Martinez, MD is a Senior Associate in Critical Care at Boston Children's Hospital, and an Assistant Professor of Anaesthesia at Harvard Medical School. She is the Director of the Pediatric Critical Care Nutrition Program in the Division of Critical Care Medicine and Principal Investigator for a clinical-translational research program on gastrointestinal function and nutrition in pediatric critical illness.Learning Objectives:By the end of this podcast, listeners should be able to:Recognize the impact of nutritional status on outcomes of critically-ill children.Describe the key aspects of the metabolic stress response in critical illness.Discuss a clinical approach to accurately estimating and prescribing nutrition in critically-ill children.Reflect on an expert's approach to managing aspects of nutrition in critically-ill children where there may not be high-quality evidence. Selected references:Mehta et al. Guidelines for the Provision and Assessment of Nutrition Support Therapy in the Pediatric Critically Ill Patient: Society of Critical Care Medicine and American Society for Parenteral and Enteral Nutrition. JPEN J Parenter Enteral Nutr. 2017 Jul;41(5):706-742. doi: 10.1177/0148607117711387. Epub 2017 Jun 2. PMID: 28686844. Fivez et al. Early versus Late Parenteral Nutrition in Critically Ill Children. N Engl J Med. 2016 Mar 24;374(12):1111-22. doi: 10.1056/NEJMoa1514762. Epub 2016 Mar 15. PMID: 26975590.Questions, comments or feedback? Please send us a message at this link (leave email address if you would like us to relpy) Thanks! -Alice & ZacSupport the showHow to support PedsCrit:Please complete our Listener Feedback SurveyPlease rate and review on Spotify and Apple Podcasts!Donations are appreciated @PedsCrit on Venmo , you can also support us by becoming a patron on Patreon. 100% of funds go to supporting the show. Please remember that all content during this episode is intended for educational and entertainment purposes only. It should not be used as medical advice. The views expressed during this episode by hosts and our guests are their own and do not reflect the official position of their institutions. If you have any comments, suggestions, or feedback-you can email us at pedscritpodcast@gmail.com. You can also check out our website at http://www.pedscrit.com. Thank you for listening to this episode of PedsCrit!

Sonal N. Shah, MD, MPH, Division of Emergency Medicine, Boston Children's Hospital, Harvard Medical School, discusses the Rational Clinical Examination article "Has This Child Experienced Physical Abuse?" with JAMA Associate Editor David L. Simel, MD, MHS. Related Content: Has This Child Experienced Physical Abuse?

Enid Martinez, MD is a Senior Associate in Critical Care at Boston Children's Hospital, and an Assistant Professor of Anaesthesia at Harvard Medical School. She is the Director of the Pediatric Critical Care Nutrition Program in the Division of Critical Care Medicine and Principal Investigator for a clinical-translational research program on gastrointestinal function and nutrition in pediatric critical illness. Learning Objectives:By the end of this podcast, listeners should be able to:Recognize the impact of nutritional status on outcomes of critically-ill children.Describe the key aspects of the metabolic stress response in critical illness.Discuss a clinical approach to accurately estimating and prescribing nutrition in critically-ill children.Reflect on an expert's approach to managing aspects of nutrition in critically-ill children where there may not be high-quality evidence. Selected references:Mehta et al. Guidelines for the Provision and Assessment of Nutrition Support Therapy in the Pediatric Critically Ill Patient: Society of Critical Care Medicine and American Society for Parenteral and Enteral Nutrition. JPEN J Parenter Enteral Nutr. 2017 Jul;41(5):706-742. doi: 10.1177/0148607117711387. Epub 2017 Jun 2. PMID: 28686844. Fivez et al. Early versus Late Parenteral Nutrition in Critically Ill Children. N Engl J Med. 2016 Mar 24;374(12):1111-22. doi: 10.1056/NEJMoa1514762. Epub 2016 Mar 15. PMID: 26975590.Questions, comments or feedback? Please send us a message at this link (leave email address if you would like us to relpy) Thanks! -Alice & ZacSupport the showHow to support PedsCrit:Please complete our Listener Feedback SurveyPlease rate and review on Spotify and Apple Podcasts!Donations are appreciated @PedsCrit on Venmo , you can also support us by becoming a patron on Patreon. 100% of funds go to supporting the show. Thank you for listening to this episode of PedsCrit. Please remember that all content during this episode is intended for educational and entertainment purposes only. It should not be used as medical advice. The views expressed during this episode by hosts and our guests are their own and do not reflect the official position of their institutions. If you have any comments, suggestions, or feedback-you can email us at pedscritpodcast@gmail.com. Check out http://www.pedscrit.com for detailed show notes. And visit @critpeds on twitter and @pedscrit on instagram for real time show updates.

This week we go back in time to 2020 to delve into the topic of fellow wellness and review a work from the Boston Children's group on fellow fears and stressors when beginning their training. Are there patterns amongst the fellow concerns that can be identified and used to inform interventions to help allay these fears and reduce the stress? We speak with Dr. David Brown, Associate Professor of Pediatrics, Harvard Medical School and also Dr. Tony Pastor who was then the ACHD Fellow at Boston Children's Hospital/Brigham and Women's Hospital about their thoughts on fellow fears and stressors as well as fellow (and doctor) wellness. doi: 10.1007/s00246-019-02276-z.

Welcome to the NeurologyLive® Mind Moments® podcast. Tune in to hear leaders in neurology sound off on topics that impact your clinical practice. In this episode, "Understanding Variability in Infantile Spasms Care," Christina Briscoe, MD, epileptologist at Boston Children's Hospital, discusses new multi-center findings on current treatment practices for infantile epileptic spasms syndrome (IESS). Briscoe outlines why first- and second-line therapies remain largely standardized, yet significant variability emerges once hormonal therapy and vigabatrin fail. She details the evidence gaps driving inconsistent third-line and fourth-line decision-making, including limited clinical trial data, uneven access to ketogenic diet programs and epilepsy surgery, and historically low industry investment in infant-specific trials. Additional discussion focuses on ongoing research from the Pediatric Epilepsy Research Consortium, national and global comparisons in treatment pathways, barriers to study scalability in rare pediatric epilepsies, and the practical challenges of implementing timely diagnosis and standardized care across diverse healthcare settings. Briscoe also highlights under-recognized issues such as incorporation of ketogenic diet and early surgical evaluation into treatment pathways, and emphasizes the need for broader infrastructure, funding, and multi-center collaboration to improve outcomes for children with IESS. Looking for more Epilepsy discussion? Check out the NeurologyLive® Epilepsy clinical focus page. Episode Breakdown: 1:05 – Origins of the study, need to pursue more standardized care in IESS 4:40 – Reasons behind treatment variability after first and second-line options 8:00 – What research is needed to guide sequencing and standardize care 12:05 – Neurology News Minute 14:30 – What makes IESS studies difficult and how infrastructure can improve 18:50 – Lesser-discussed gaps, including ketogenic diet and surgical evaluation The stories featured in this week's Neurology News Minute, which will give you quick updates on the following developments in neurology, are further detailed here: Positive Phase 3 OCEANIC-STROKE Data Position Asundexian for Upcoming FDA Submission FDA Approves New Intrathecal Administration Route for Spinal Muscular Atrophy Gene Therapy GLP-1 Semaglutide Fails to Outperform Placebo in Phase 3 EVOKE Trial of Alzheimer Disease Thanks for listening to the NeurologyLive® Mind Moments® podcast. To support the show, be sure to rate, review, and subscribe wherever you listen to podcasts. For more neurology news and expert-driven content, visit neurologylive.com.

Dystrophinopathies are heritable muscle disorders caused by pathogenic variants in the DMD gene, leading to progressive muscle breakdown, proximal weakness, cardiomyopathy, and respiratory failure. Diagnosis and management are evolving areas of neuromuscular neurology. In this episode, Kait Nevel, MD, speaks with Divya Jayaraman, MD, PhD, an author of the article "Dystrophinopathies" in the Continuum® October 2025 Muscle and Neuromuscular Junction Disorders issue. Dr. Nevel is a Continuum® Audio interviewer and a neurologist and neuro-oncologist at Indiana University School of Medicine in Indianapolis, Indiana. Dr. Jayaraman is an assistant professor of neurology and pediatrics in the division of child neurology at the Columbia University Irving Medical Center in New York, New York. Additional Resources Read the article: Dystrophinopathies Subscribe to Continuum®: shop.lww.com/Continuum Earn CME (available only to AAN members): continpub.com/AudioCME Continuum® Aloud (verbatim audio-book style recordings of articles available only to Continuum® subscribers): continpub.com/Aloud More about the American Academy of Neurology: aan.com Social Media facebook.com/continuumcme @ContinuumAAN Host: @IUneurodocmom Full episode transcript available here Dr Jones: This is Dr Lyell Jones, Editor-in-Chief of Continuum. Thank you for listening to Continuum Audio. Be sure to visit the links in the episode notes for information about earning CME subscribing to the journal, and exclusive access to interviews not featured on the podcast. Dr Nevel: Hello, this is Dr Kate Nevel. Today I'm interviewing Dr Divya Jayaraman about her article on dystrophinopathies, which she wrote with Dr Partha Ghosh. This article appears in the October 2025 Continuum issue on muscle and neuromuscular junction disorders. Divya, welcome to the podcast, and please introduce yourself to the audience. Dr Jayaraman: Thank you so much, Dr Nevel. My name is Divya, and I am an assistant professor of Neurology and Pediatrics at Columbia University Irving Medical Center, and also an attending physician in the Pediatric Neuromuscular program there. In that capacity, I see patients with pediatric neuromuscular disorders and also some general pediatric neurology patients and also do research, primarily clinical research and clinical trials on pediatric neuromuscular disorders. Dr Nevel: Wonderful. Thank you for sharing that background with us. To set us on the same page for our discussion, before we get into some more details of the article, perhaps, could you start with some definitions? What comprises the dystrophinopathies? What are some of the core features? Dr Jayaraman: So, the dystrophinopathies, I like that term because it is a smaller subset from the muscular dystrophies. The dystrophinopathies are a spectrum of clinical phenotypes that are all associated with mutations in the DMD gene on chromosome X. So, that includes DMD---or, Duchenne muscular dystrophy---, Becker muscular dystrophy, intermediate muscular dystrophy (which falls in between the two), dilated cardiomyopathy, asymptomatic hyperCKemia, and manifesting female carriers. In terms of the core features of these conditions, so, there's some variability, weakness being prominent in Duchenne and also Becker. The asymptomatic hyperCKemia, on the other hand, may have minimal symptoms and might be found incidentally by just having a high CK on their labs. They all will have some degree of elevated CK. The dilated cardiomyopathy patients, and also the Becker patients to a lesser degree, will have cardiac involvement out of proportion to skeletal muscle involvement, and then the manifesting carriers likewise can have elevated CK and prominent cardiac involvement as well as some milder weakness. Dr Nevel: Now that we have some definitions, for the practicing neurologists out there, what do you think is the most important takeaway from your article about the dystrophinopathies? Dr Jayaraman: I like this question because it suggests that there's something that, really, any neurologist could do to help us pick up these patients sooner. And the big takeaway I want everyone to get from this is to check the CK, or creatine kinase, level. It's a simple, cheap, easy test that anyone can order, and it really helps us a lot in terms of setting the patient on the diagnostic odyssey. And in terms of whom you should be thinking about checking a CK in, obviously patients who present with some of the classic clinical features of Duchenne muscular dystrophy. This would include young boys who have toe walking, as they're presenting, sign; or motor delayed, delayed walking. They may have calf hypertrophy, which is what we say nowadays. You might have seen calf pseudohypertrophy in your neurology textbooks, but we just say calf hypertrophy now. Or patients can often have a Gowers sign or Gowers maneuver, which is named after a person called Gowers who described this phenomenon where the child will basically turn over and use their hands on the floor to stand up, usually with a wide-based gait, and then they'll sort of march their hands up their legs. That's the sort of classic Gowers maneuver. There are modified versions of that as well. So, if anyone presents with this classic presentation, for sure the best first step is to check a CK. But I would also think about checking a CK for some atypical cases. For example, any boy with any kind of motor or speech delay for whom you might not necessarily be thinking about a muscle disorder, it's always good practice to check a CK. Even a boy with autism for whom you may not get a good clinical exam. This patient might present to a general pediatric neurology clinic. I always check a CK in those patients, and you'll pick up a lot of cases that way. For the adult folks in particular, the adult neurologist, a female patient could show up in your clinic with asymptomatic hyperCKemia. And I think it's an important differential to think about for them because this could have implications not just for their own cardiac risks, but also for their family planning. Dr Nevel: So, tell us a little bit more about the timing of diagnosis. Biggest takeaway: check a CK if this is anywhere on your radar, even if somewhat of an atypical case. Why is it so important to get kiddos started on that diagnostic odyssey, as you called it, early? Dr Jayaraman: This is especially important for kids because if they especially get a Duchenne muscular dystrophy diagnosis, you might be making them eligible for treatments that we've had for some time, and also treatments that were not available earlier that hinge on making that diagnosis. So, for example, people may be skeptical about steroids, but there's population data to suggest that initiation and implementation of steroids could delay the onset of loss of ambulation as much as three years. So, you don't want to deprive patients of the chance to get that. And then all the newer emerging therapies---which we'll be talking about later, I'm sure---require a Duchenne muscular dystrophy diagnosis. So, that's why it's so important to check a CK, have this on your radar, and then get them to a good specialist. Dr Nevel: I know that you alluded already, or shared a few of the kind of exam paroles or findings among patients with dystrophinopathy. But could you share with us a little bit more how you approach these patients in the clinic who are presenting with muscle weakness, perhaps? And how do you approach this or think about this in terms of ways to potentially differentiate between a dystrophinopathy versus another cause of motor weakness or delay? Dr Jayaraman: It's helpful to think through the neuraxis and what kinds of disorders can present along that neuraxis. A major differential that I'm always thinking about when I'm seeing a child with proximal weakness is spinal muscular atrophy, which is a genetic anterior horn cell disorder that can also present in this age group. And some of the key differences there would be things like reflexes. So, you should have dropped reflexes in spinal muscular atrophy. In DMD, surprisingly, they might have preserved Achilles reflexes even if their patellar reflexes are lost. It may only be much later that they go on to lose their Achilles reflex. So, if you can get an Achilles reflex, that's quite reassuring, and if you cannot, then you need to be thinking about spinal muscular atrophy. They can both have low muscle tone and can present quite similarly, including with proximal weakness, and can even have neck flexion weakness. So, this is an important distinction to make. The reason for that is, obviously there are treatments for both conditions, but for spinal muscular atrophy, timing is very, very important. Time is motor neurons, so the sooner you make that diagnosis the better. Other considerations would be the congenital muscular dystrophies. So, for those that they tend to present a lot younger, like in infancy or very early on, and they can have much, much higher CKS in that age range than a comparable Duchenne or Becker muscular dystrophy patient. They can also have other involvement of the central nervous system that you wouldn't see in the dystrophinopathies, for example. My mnemonic for the congenital muscular dystrophies is muscle-eye-brain disease, which is one of the subtypes. So, you think about muscle involvement, eye involvement, and brain involvement. So, they need an ophthalmology valve. They can have brain malformations, which you typically don't see in the dystrophinopathies. I think those are some of the major considerations that I have. Obviously, it's always good to think about the rest of the neuraxis as well. Like, could this be a central nervous system process? Do they have upper motor neuron signs? But that's just using all of your exam tools as a neurologist. Dr Nevel: Yeah, absolutely. So, let's say you have a patient in clinic and you suspect they may have a dystrophinopathy. What is your next diagnostic step after your exam? Maybe you have an elevated CK and you've met with the patient. What comes next? Dr Jayaraman: Great question. So, after the CK, my next step is to go to genetics. And this is a bit of a change in practice over time. In the past we would go from the CK to the muscle biopsy before genetic testing was standard. And I think now, especially in kids, we want to try and spare them invasive procedures where possible. So, genetic testing would be the next step. There are a few no-charge, sponsored testing programs for the dystrophinopathies and also for some of the differential diagnosis that I mentioned. And I think we'll be including links to websites for all of these in the final version of the published article. So, those are a good starting point for a genetic workup. It's really important to know that, you know, deletions and duplications are a very common type of mutation in the DMD gene. And so, if you just do a very broad testing, like whole exome, you might miss some of those duplications and deletions. And it's important to include both checking for duplications and deletions, and also making sure that the DMD gene is sequenced. So always look at whatever genetic test you're ordering and making sure that it's actually going to do what you want it to do. After genetics, I think that the sort of natural question is, what if things are not clear after the genetics for some reason? We still use biopsy in this day and age, but we save it for those cases where it's not entirely clear or maybe the phenotype is a little bit discordant from the genotype. So, for mutations that disrupt the reading frame, those tend to cause Duchenne muscular dystrophy, whereas mutations that preserve the reading frame tend to cause Becker muscular dystrophy. There are some important exceptions to this, which is where muscle biopsy can be especially helpful in sorting it out. So, for example, there are some early mutations early in the DMD gene where, basically, they find an alternate start codon or an initiation codon to continue with transcription and translation. So, you end up forming a largely functional, somewhat truncated protein that gives you more of a milder Becker phenotype. On the other hand, you can have some non-frameshift or inframe mutations that preserve the reading frame, but because they disrupt a very key domain in the protein that's really crucial for its function, you can actually end up with a much more severe Duchennelike phenotype. So, for these sorts of cases, you might know a priori you're dealing with them, but might just be a child who is who you think has DMD has a mutation that's showed up on testing. There isn't enough in the literature to point you one way or another, but they look maybe a little milder than you would expect. That would be a good kid to do a biopsy in because there are treatment decisions that hinge on this. There are treatments that are only for Duchenne that someone with a milder phenotype would not be eligible for. Dr Nevel: So, that kind of stepwise approach, but maybe not all kids need a muscle biopsy is what I'm hearing from you. If it's a mutation that's been well-described in the literature to be fitting with Duchenne, for example. Dr Jayaraman: Absolutely. Dr Nevel: So, after you confirm the diagnosis through genetic testing---and let's say, you know, whether or not you do a muscle biopsy or not, after you know the diagnosis is a dystrophinopathy---how do you counsel the families and your patients? What are the most important points to relay to families, especially in that initial phase where the diagnosis is being made? Dr Jayaraman: This is a lot of what we do in pediatric neurology in general, right? So, I actually picked up this approach from the pediatric hematology oncology specialists at Boston Children's. They had this concept of a day-zero conversation, which is the day that you disclose the life-changing diagnosis or potentially, at some point, terminal diagnosis to a family. And some of the key components of that are a not beating around the bush, telling them what the diagnosis is, and then letting them have whatever emotional response they're going to have in the moment. And you may not get much further than that, but honestly, you want them to take away, this is what my child has. I did not do anything to cause this, nor could I have done anything to prevent this. Because often for these genetic conditions, there's a lot of guilt, a lot of parental guilt. So, you want to try and assuage that as much as possible. And then to know that they're not going to be alone on this journey; that, you know, they don't have to have it all figured out right then, but we can always come back and answer any questions they have. There's going to be a whole team of specialists. We're going to help the family and the kid manage this condition. Those are sort of my big takeaways that I want them to get. Dr Nevel: Right. And that segues into my next question, which is, who is part of that team? I know that these teams that help take care of people with dystrophinopathies and other muscle disorders can be very large teams that span multiple specialists. Can you talk a little bit more about that for this group of patients? Dr Jayaraman: Of course. So, the neuromuscular neurologist, really, our role is in coordinating the diagnosis, the initiation of any disease-specific treatments, and coordinating care with a whole group of specialists. So, we're sort of at the center of that, but everyone else is equally important. So, the other specialists include physical therapists; occupational therapists; rehab doctors or physiatrists; orthotists who help with all of the many braces and other devices that they might need, wheelchairs; pulmonology, of course, for managing the respiratory manifestations of this. It becomes increasingly important over time, and they are involved early on to help monitor for impending respiratory problems. Cardiac manifestations, this is huge and something that you should be thinking about even for your female carriers, the mother of the patient you're seeing in the clinic, or your patient who comes to adult clinic with asymptomatic hyperCKemia. if you end up making a diagnosis of DMD carrier for those patients, or if you make a Becker diagnosis, the cardiac surveillance is even more important because the cardiac involvement can be out of proportion to the skeletal muscle weakness. And of course, extremely important for the Duchenne patients as well. Endocrinologists are hugely important because in the course of treating patients with steroids, we end up giving them a lot of iatrogenic endocrinologic complications. Like they might have delayed puberty, they might have loss of growth, of height; and of course metabolic syndrome. So, endocrinology is hugely important. They're also important in managing things like fracture prevention, osteoporosis, prescribing bisphosphonates if necessary. Nutrition and GI are also important, not just later on when they might need assistance to take in nutrition, whether that's through tube feeds, but also earlier on when we're trying to manage the weight. Orthopedics, of course, for the various orthopedic complications that patients develop. And then finally, a word must be said for social work and behavioral and mental health specialists, because a lot of this patient population has a lot of mental health challenges as well. Dr Nevel: After you give the diagnosis, you've counseled the patient and families and you've had those kind of initial phase discussions, the day-zero discussion, when you start getting into discussions or thoughts about management, disease-specific medication. But what are the main categories of the treatment options, and maybe how do you kind of approach deciding between treatment options for your patients? Dr Jayaraman: So, there are two broad categories that I like to think about. So, one is the oral corticosteroids and oral histone deacetylase, or HDAC inhibitors, which share the common characteristic that they are non-mutation specific. And within corticosteroids, patients now have a choice between just Prednisone or Prednisolone, or Deflazacort or Vermilion. The oral HDAC inhibitors are newly FDA-approved as a nonsteroidal therapy in addition to corticosteroids in DMD patients above six years of age. I would say we're in the early phase of adoption of this in clinical practice. And then the other big category of treatment options would be the genetic therapies as a broad bucket, and this would include gene therapy or gene replacement therapy, of which the most famous is the microdystrophin gene therapy that was FDA-approved first on an accelerated approval basis for ages four to eight, and then a full approval in that age group as well as an accelerated approval for all comers, essentially, with DMD. This is obviously controversial. Different centers approach this a bit differently. I think our practice at our site has been to focus on the ambulatory population, just thinking about risk versus benefit, because the risks are not insignificant. So really this is something that should be done by experienced sites that have the bandwidth and the wherewithal to counsel patients through all of this and to manage complications as they arise with regular monitoring. And then another class that falls within this broader category would be the Exon-skipping therapies. So as the name suggests, they are oligonucleotides that cause an Exon to be skipped. The idea is, if there is a mutation in a particular Exon that causes a frame shift, and there's an adjacent Exon that you can force skipping of, then the resulting protein, when you splice the two ends together, will actually allow restoration of the reading frame. I think the picture I want to paint is that there's a wide range of options that we present to families, not all of which everyone will be eligible for. And they all have different risk profiles. And I really think the choice of a particular therapy has to be a risk-benefit decision and a shared decision-making process between the physician and the family. Dr Nevel: What is going on in research in this area? And what do you think will be the next big breakthrough? I know before we started the recording you had mentioned that there's a lot of things going on that are exciting. And so, I'm looking forward to hearing more. Dr Jayaraman: Of course. So, I'll be as quick as I can with this. But I mentioned that next-generation Exon skipping therapies, I think the hope is that they will be better at delivering the Exon skipping to the target tissue and cells and that they might be more efficacious. I'm also excited about next-generation gene therapies that might target muscle more specifically and hopefully reduce the off-target effects, or combination use of gene therapies with other immunosuppressive regimens to improve the safety profile and maybe someday allow redosing, which we cannot do currently. Or potentially targeting the satellite cells, which are the muscle stem cells, again, to improve the long term durability of these genetic therapies. Dr Nevel: That's great, thank you for sharing. Thank you so much for talking to me today about your article. I really enjoyed learning more about the dystrophinopathies. Today I've been interviewing Dr Divya Jayaraman about her article on the dystrophinopathies, which she wrote with Dr Partha Ghosh. This article appears in the October 2025 Continuum issue on muscle and neuromuscular junction disorders. Please be sure to check out the Continuum Audio episodes from this and other issues. Also, please read the Continuum articles for more details than what we were able to get to today during our discussion. Thank you, as always, so much to the listeners for joining us today, and thank you, Divya, for sharing all of your knowledge with us today. Dr Jayaraman: Thank you so much for having me on the podcast. Dr Monteith: This is Dr Teshamae Monteith, Associate Editor of Continuum Audio. If you've enjoyed this episode, you'll love the journal, which is full of in-depth and clinically relevant information important for neurology practitioners. Use the link in the episode notes to learn more and subscribe. AAN members, you can get CME for listening to this interview by completing the evaluation at continpub.com/audioCME. Thank you for listening to Continuum Audio.

In this World Shared Practice Forum Podcast, Dr. Vinay Nadkarni discusses emergent tracheal intubation in pediatric critical care. Drawing from the NEAR4KIDS registry and comparing with recent adult-focused evidence, Dr. Nadkarni discusses the challenges of airway management in children, emphasizing the importance of patient-specific physiology. He highlights how patient positioning and equipment choices can improve intubation outcomes. Additionally, the episode explores the benefits of video laryngoscopy and apneic oxygenation. This content is pertinent for healthcare professionals seeking to enhance their understanding of pediatric airway management, offering practical insights supported by recent research. LEARNING OBJECTIVES - Compare pediatric and adult emergency tracheal intubation evidence and practices - Explore the role of the NEAR4KIDS registry in improving pediatric intubation practices - Identify effective strategies to enhance first-attempt success in tracheal intubations - Assess the impact of patient positioning and equipment choices on intubation outcomes - Evaluate the benefits of video laryngoscopy and apneic oxygenation in pediatric settings AUTHORS Vinay Nadkarni, MD, MS Professor, Anesthesiology Critical Care and Pediatrics University of Pennsylvania Perelman School of Medicine Jeffrey Burns, MD, MPH Emeritus Chief Division of Critical Care Medicine Department of Anesthesiology, Critical Care and Pain Medicine Boston Children's Hospital Professor of Anesthesia Harvard Medical School DATE Initial publication date: November 25, 2025. ARTICLES REFERENCED - DeMasi SC, Casey JD, Semler MW. Evidence-based Emergency Tracheal Intubation. Am J Respir Crit Care Med. 2025;211(7):1156-1164. doi:10.1164/rccm.202411-2165CI - Garcia-Marcinkiewicz AG, Kovatsis PG, Hunyady AI, et al. First-attempt success rate of video laryngoscopy in small infants (VISI): a multicentre, randomised controlled trial. Lancet. 2020;396(10266):1905-1913. doi:10.1016/S0140-6736(20)32532-0 - Hagberg CA, Artime CA, Aziz MF, eds. Hagberg and Benumof's Airway Management. 5th ed. Philadelphia, PA: Elsevier; 2023. - Khanam D, Schoenfeld E, Ginsberg-Peltz J, et al. First-Pass Success of Intubations Using Video Versus Direct Laryngoscopy in Children With Limited Neck Mobility. Pediatr Emerg Care. 2024;40(6):454-458. doi:10.1097/PEC.0000000000003058 - Waheed S, Kapadia NN, Jawed DR, Raheem A, Khan MF. Randomized controlled trial to assess the effectiveness of apnoeic oxygenation in adults using a low-flow or high-flow nasal cannula with head side elevation during endotracheal intubation in the emergency department. BMC Res Notes. 2025 Jul 1;18(1):264. doi: 10.1186/s13104-025-07328-7. Erratum in: BMC Res Notes. 2025 Sep 8;18(1):384. doi: 10.1186/s13104-025-07412-y. PMID: 40598378; PMCID: PMC12219693. TRANSCRIPT https://cdn.bfldr.com/D6LGWP8S/as/mr2657n4ckgpz7g3tw37gbx/202511_WSP_Nadkarni_transcript Please visit: http://www.openpediatrics.org OPENPediatrics™ is an interactive digital learning platform for healthcare clinicians sponsored by Boston Children's Hospital and in collaboration with the World Federation of Pediatric Intensive and Critical Care Societies. It is designed to promote the exchange of knowledge between healthcare providers around the world caring for critically ill children in all resource settings. The content includes internationally recognized experts teaching the full range of topics on the care of critically ill children. All content is peer-reviewed and open-access thus at no expense to the user. For further information on how to enroll, please email: openpediatrics@childrens.harvard.edu CITATION Nadkarni V, Burns JP. Pediatric Intubation Practices: Insights from NEAR4KIDS. 11/2025. OPENPediatrics. Online Podcast. https://soundcloud.com/openpediatrics/pediatric-intubation-practices-insights-from-near4kids-by-v-nadkarni-openpediatrics.

Does cannabis use have any effect, good or bad, on Orthopaedic Surgery? It's a question we, as a Sports Medicine community, hear increasingly frequently from our patients but so far don't have great data to provide sound advice. We welcome Dr. Grant Hogue who has studied this extensively across several disciplines of Orthopaedic Surgery. He presents his work with his colleagues at Boston Children's Hospital looking specifically at adverse effects of marijuana use on ACL reconstruction recovery.

In this Nursing World Shared Practice Forum Podcast, Dr. Bernadette Melnyk, a globally renowned expert in evidence-based practice (EBP), discusses the critical importance of EBP in healthcare. This podcast covers the history of EBP, its impact on patient outcomes, and the return on investment for healthcare systems. Dr. Melnyk shares insights on building a culture that supports EBP, the role of EBP mentors, and the importance of clinician well-being. LEARNING OBJECTIVES - Identify strategies for creating and sustaining a culture that prioritizes EBP within healthcare organizations - Recognize the role of EBP mentors in facilitating the implementation of evidence-based changes - Explore the relationship between EBP, clinician well-being, and job satisfaction - Understand the organizational benefits of EBP initiatives as measured by return on investment (ROI) and value of investment (VOI) - Learn the difference between EBP and Implementation Science AUTHORS Bernadette Melnyk, PhD, APRN-CNP, EBP-C, FAANP, FNAP, FAAN CEO and Founder, COPE2Thrive, LLC President and Co-Founder, EBP Solutions, LLC Professor and Dean Emeriti Editor-in-Chief, Worldviews on Evidence-based Nursing Ethan Schuler, DNP, RN, CPNP-AC/PC, APN II Surgical Nurse Practitioner, Division of Critical Care Medicine Boston Children's Hospital DATE Initial publication date: November 18, 2025. ARTICLES REFERENCED 1) Melnyk BM, Strait LA, Beckett C, Hsieh AP, Messinger J, Masciola R. The state of mental health, burnout, mattering and perceived wellness culture in Doctorally prepared nursing faculty with implications for action. Worldviews Evid Based Nurs. 2023;20(2):142-152. doi:10.1111/wvn.12632 2) Melnyk BM, Hsieh AP, Tan A, et al. Associations Among Nurses' Mental/Physical Health, Lifestyle Behaviors, Shift Length, and Workplace Wellness Support During COVID-19: Important Implications for Health Care Systems. Nurs Adm Q. 2022;46(1):5-18. doi:10.1097/NAQ.0000000000000499 3) Melnyk BM, Davidson JE, Tucker S, et al. Burnout, Mental Health, and Workplace Characteristics: Contributors and Protective Factors Associated With Suicidal Ideation in High-Risk Nurses. Worldviews Evid Based Nurs. 2025;22(3):e70042. doi:10.1111/wvn.70042 4) Melnyk BM, Hsieh AP, Messinger J, Thomas B, Connor L, Gallagher-Ford L. Budgetary investment in evidence-based practice by chief nurses and stronger EBP cultures are associated with less turnover and better patient outcomes. Worldviews Evid Based Nurs. 2023;20(2):162-171. doi:10.1111/wvn.12645 TRANSCRIPT Please visit: http://www.openpediatrics.org OPENPediatrics™ is an interactive digital learning platform for healthcare clinicians sponsored by Boston Children's Hospital and in collaboration with the World Federation of Pediatric Intensive and Critical Care Societies. It is designed to promote the exchange of knowledge between healthcare providers around the world caring for critically ill children in all resource settings. The content includes internationally recognized experts teaching the full range of topics on the care of critically ill children. All content is peer-reviewed and open-access thus at no expense to the user. For further information on how to enroll, please email: openpediatrics@childrens.harvard.edu CITATION Melnyk BM, Schuler E, DeGrazia M. Transforming Healthcare with Evidence-Based Practice. 11/2025. OPENPediatrics. Online Podcast. https://soundcloud.com/openpediatrics/transforming-healthcare-with-evidence-based-practice-by-b-melnyk-openpediatrics.

Missed PCICS 2025? Join hosts Deanna Tzanetos MD (Norton Children's Hospital/U of Louisville), Kavipriya Komeswaran MD (U of Mississippi) and Maria Batsis MD (Lucile Packard Children's/Stanford University) as they interview two of the speakers from the PCICS 2025 session on the challenges of Shone's Complex- Michael DiMaria MD (Rocky Mountain Children's Hospital) and Jessica Barreto MD, MS (Boston Children's Hospital, Harvard University). Editor and Producer: Lillian Su, MD (Children's National Hospital).

S7 E3: Autism and Executive Functions w/Dr. Susan FajaIn this episode, Gerald and Alexis are joined by Dr. Susan Faja - clinical psychologist from Boston Children's Hospital - to discuss executive functions among individuals on the Autism spectrum. In this valuable discussion, you will learn how executive function challenges present in ASD, the individual differences among the ASD population, how to support executive function for those with ASD, and recent research findings about Autism.Dr. Susan Faja, who is a psychologist at Boston Children's Hospital specializing in the research of individuals with Autism, particularly children. The Faja Lab led by Dr. Faja seeks to understand changes in brain systems of executive control, social cognition and social perception resulting from targeted interventions that use electrophysiological as well as behavioral measurement tools. She leads the Faja Lab, where her approach allows for the exploration of the developmental processes that contribute to behavioral symptoms, clarifies how interventions work, and provides a platform for rigorously testing novelinterventions. Additionally, Dr. Faja seeks to understand why and how individuals with Autism can present so differently in their development, as a way to better understand causes and inform individualized treatments.

In this special Complex Care Journal Club podcast episode, host Dr. Kilby Mann interviews presenters of posters and oral abstracts relevant to the care of children with medical complexity at the American Academy for Cerebral Palsy and Developmental Medicine (AACPDM) 79th Annual Meeting, October 15-18, 2025, in New Orleans, Louisiana. Speakers describe their study findings and implications for practice. Dr. Francisco Valencia also discusses the role of the Complex Care Committee and the profound impact of mentorship in the field of complex care. SPEAKERS Laura Brunton, PT, PhD, Associate Professor, School of Physical Therapy, Western University, London, Ontario, Canada Caitlin Cassidy, MD, Associate Professor, Department of Physical Medicine and the Department of Rehabilitation and Pediatrics, Western University, London, Ontario, Canada Susan Gibb, MBBS, FRACP, Medical Lead, Complex Care Hub, Royal Children's Hospital, Melbourne, Australia Francisco Valencia, MD, Pediatric Orthopedic Surgeon, Children's Clinics For Rehabilitative Services, Tucson, Arizona Simran Prakash, BA, Medical Student, University of Miami Miller School of Medicine Karen Pratt, BA, MSc, PhD Candidate, Western University School of Health Sciences, London, Ontario, Canada Claire Wallace, PhD, Pediatric Psychologist, Ranken Jordan Pediatric Bridge Hospital, Maryland Heights, Missouri Esther Yap, BPharm, MD, Physician, Royal Children's Hospital, Melbourne, Australia HOST Kilby Mann, MD, Assistant Professor, Pediatric Rehabilitation Medicine, Children's Hospital Colorado DATE Initial publication date: November 11, 2025. RESOURCES REFERENCED - American Academy for Cerebral Palsy and Developmental Medicine (AACPDM) 29th Annual Meeting, October 15-18, 2025, New Orleans, LA. https://www.aacpdm.org/events/2025/program - American Academy for Cerebral Palsy and Developmental Medicine (AACPDM), www.aacpdm.org/ - AACPDM Complex Care Committee (www.aacpdm.org/about-us/committees/complex-care) TRANSCRIPT https://cdn.bfldr.com/D6LGWP8S/as/bgmft56r8ksk85qxbthvzs/CCJCP_AACPDM_Transcript_11-4-25‌ Clinicians across healthcare professions, advocates, researchers, and patients/families are all encouraged to engage and provide feedback! You can recommend an article for discussion using this form: https://forms.gle/Bdxb86Sw5qq1uFhW6. Please visit: http://www.openpediatrics.org OPENPediatrics™ is an interactive digital learning platform for healthcare clinicians sponsored by Boston Children's Hospital and in collaboration with the World Federation of Pediatric Intensive and Critical Care Societies. It is designed to promote the exchange of knowledge between healthcare providers around the world caring for critically ill children in all resource settings. The content includes internationally recognized experts teaching the full range of topics on the care of critically ill children. All content is peer-reviewed and open-access thus at no expense to the user. For further information on how to enroll, please email: openpediatrics@childrens.harvard.edu CITATION Valencia F, Brunton L, Cassidy C, Gibb S, Prakash S, Pratt K, Wallace C, Yap E, Mann K. Practice-Changing Research in Complex Care at the AACPDM Annual Meeting 2025. 11/2025. OPENPediatrics. Online Podcast.‌ https://soundcloud.com/openpediatrics/practice-changing-research-in-complex-care-at-the-aacpdm-annual-meeting-2025.

Send us a textJoin Dr. Grant Hogue as he talks with his office mate, Dr. John Emans, the 2025 Lifetime Achievement Award Winner! This prestigious honor recognizes an SRS member for distinguished service to the Society as well as significant contributions to spinal deformity care. Listen to hear about what lead him to where he is today and his amazing career at Boston Children's Hospital. *The Scoliosis Research Society (SRS) podcast is aimed at delivering the most current and trusted information to clinicians that care for patients with scoliosis and other spinal conditions. From news in the world of spinal conditions, to discussions with thought leaders in the field, we aim to provide up-to-date, quality information that will impact the daily practice of spinal conditions.

Milk has long been sold as the key to strong bones, but research challenges that claim: many people don't tolerate dairy, calcium needs are lower than advertised, and higher milk intake doesn't necessarily prevent fractures. Politics and industry marketing helped set “three glasses a day,” even though healthy bones depend more on overall diet and lifestyle—things like vitamin D, movement, and avoiding soda, excess sugar, and stress that drive calcium loss. Dairy may be helpful for some diets, but it can also trigger bloating, acne, congestion, or digestive issues. The good news is that strong bones and good nutrition are still very doable without cow's milk—think leafy greens, sardines, almonds, chia, and sunshine for vitamin D. In this episode, I discuss, along with Dr. David Ludwig and Dr. Elizabeth Boham why bone health depends more on diet, lifestyle, and nutrient balance than on dairy. David S. Ludwig, MD, PhD, is an endocrinologist and researcher at Boston Children's Hospital, Professor of Pediatrics at Harvard Medical School, and Professor of Nutrition at the Harvard T.H. Chan School of Public Health. He co-directs the New Balance Foundation Obesity Prevention Center and founded the Optimal Weight for Life (OWL) program, one of the nation's largest clinics for children with obesity. For over 25 years, Dr. Ludwig has studied how diet composition affects metabolism, body weight, and chronic disease risk, focusing on low glycemic index, low-carbohydrate, and ketogenic diets. Called an “obesity warrior” by Time Magazine, he has championed policy changes to improve the food environment. A Principal Investigator on numerous NIH and philanthropic grants, Dr. Ludwig has published over 200 scientific articles and three books for the public, including the #1 New York Times bestseller Always, Hungry? Dr. Elizabeth Boham is Board Certified in Family Medicine from Albany Medical School, and she is an Institute for Functional Medicine Certified Practitioner and the Medical Director of The UltraWellness Center. Dr. Boham lectures on a variety of topics, including Women's Health and Breast Cancer Prevention, insulin resistance, heart health, weight control and allergies. She is on the faculty for the Institute for Functional Medicine. This episode is brought to you by BIOptimizers. Head to bioptimizers.com/hyman and use code HYMAN to save 15%. Full-length episodes can be found here:Why Most Everything We Were Told About Dairy Is Wrong Is It Okay To Eat Cheese And What Types Of Dairy Should You Avoid? Is Lactose Intolerance Causing Your Gut Issues?

The Triple Threat to the Rare Disease Ecosystem — A Conversation with Dr. Wendy ChungSometimes you come across someone whose work changes the way you think about an entire field. That's exactly what happened when I read about Dr. Wendy Chung in Rare Revolution Magazine.Dr. Chung is one of those rare people who stands at the intersection of science, medicine, ethics, and humanity. She's a clinical and molecular geneticist, the Chief of Pediatrics at Boston Children's Hospital, and the Mary Ellen Avery Professor at Harvard Medical School. She leads NIH-funded research into the genetics of conditions like pulmonary hypertension, autism, birth defects, and a wide range of rare diseases. She's advanced newborn screening for life-threatening disorders like spinal muscular atrophy and Duchenne muscular dystrophy — work that means the difference between life and death for many families. She's been recognized with the Rare Impact Award from NORD, is a member of the National Academy of Medicine, and is a leading voice on the ethics of genomics.But titles and accolades only tell part of her story. What stands out most is her deep commitment to the people behind the science, the families living day in and day out with conditions that most of the world has never heard of.When we spoke, Dr. Chung described what she calls the “triple threat” to the rare disease ecosystem:Misinformation in health that spreads faster than facts and erodes trust in science.Lack of access to healthcare, leaving too many without the treatments they need, when they need them.Insufficient investment in research, slowing the pace of discovery and delaying life-saving therapies.Each of these challenges is daunting on its own, but together they create a fragile and often hostile environment for progress in rare disease research and care.She pointed out that while most genetic conditions are rare individually, collectively they are surprisingly common — affecting millions worldwide. That's a staggering thought, especially considering how little public awareness and funding rare diseases often receive.We also talked about autism, a condition she has studied extensively. She emphasized that autism is a spectrum, with multiple causes, the majority of which are genetic. Understanding that complexity is crucial, not only for advancing science but also for helping families cope and make informed decisions.One of the threads running through our conversation was the urgent need for better communication in science. In an age where misinformation spreads in seconds, the ability to convey facts clearly and accessibly isn't just a nice skill — it's a necessity. Miscommunication or confusion doesn't just impact public opinion; it influences policy decisions, research funding, and the direction of healthcare itself.Dr. Chung stressed that advocacy matters at every level — from the conversations parents have with their children's doctors to the policies shaped in Washington. Community engagement isn't just a feel-good idea; it's one of the most effective ways to accelerate progress. Patients, families, scientists, and policymakers all have a role to play, and collaboration among them is where breakthroughs happen.In the end, our conversation left me with two truths. First, that rare disease progress depends on persistence from so many people. The researchers who refuse to give up, from families who continue to fight for answers, and from advocates who push for change. Second, that truth itself is a kind of medicine. The more accurately, compassionately, and consistently we can communicate about rare diseases, the better chance we have at building a healthcare ecosystem that works for everyone.Dr. Wendy Chung is leading that charge, not just in the lab, but in the public square. And in this fight, both matter equally. Please like, subscribe, and comment on our podcasts!Please consider making a donation: https://thebonnellfoundation.org/donate/The Bonnell Foundation website:https://thebonnellfoundation.orgEmail us at: thebonnellfoundation@gmail.com Watch our podcasts on YouTube: https://www.youtube.com/@laurabonnell1136/featuredThanks to our sponsors:Vertex: https://www.vrtx.comViatris: https://www.viatris.com/en

In this episode, Amber Borucki, MD from Stanford Medicine, joins Host Sudheer Potru, DO, FASA, FASAM, and Co-Host Zafeer Baber, MD, to discuss acetaminophen use during pregnancy and childhood. They focus on a significant Swedish study that dispels myths about acetaminophen's links to autism, reinforcing its safety and effectiveness. Dr. Borucki highlights its role in pain management for expectant mothers and children, while the hosts discuss alternatives to opioids, like acetaminophen and ibuprofen, and stress the importance of consulting healthcare providers for proper dosing and guidance.About the GuestDr. Amber Borucki is an anesthesiologist and pain medicine specialist focused on chronic pain management in children and young adults, particularly after surgery or due to chronic conditions. She earned her medical degree from Rush Medical College and completed her residency at the University of Chicago. Dr. Borucki also underwent fellowships in pediatric anesthesiology and adult/pediatric pain medicine at Boston Children's Hospital, Brigham Women's Hospital, and Beth Israel Deaconess Medical Center. After a year of private practice in Reno, Nevada, she spent five years at UCSF as a pediatric anesthesiologist and the Director of the Pediatric Anesthesia Service at UCSF Benioff Children's Hospital.   

Dr. Yuri Maricich, Chief Medical Officer at CAMP4 Therapeutics, describes regulatory RNA, a new area of biology that recognizes the role of Reg RNA in the production of proteins from specific genes. This technology is well-suited for haploinsufficient diseases such as SYNGAP1-related disorders, in which there is a lack of healthy protein and both parents carry a copy of the mutated gene. The goal is to create disease-modifying treatments that correct the underlying genetic cause rather than treating the symptoms. Yuri explains, "What was really unique about CAMP4's scientific approach is that we're focused on a whole new and emerging area of biology called regulatory RNA. And these are control elements for the expression of genes. In other words, how much protein we get from a particular gene. And there's been a lot of work in the past on how to have less protein made, particularly if it's a protein that has a mutation that causes a problem. But in medicine, there have been very few opportunities to actually increase the amount of protein, but there are many diseases that need more healthy protein." "The backdrop of CAMP4 is that there was work done just over eight years ago at the Whitehead Institute at the Massachusetts Institute of Technology in a lab by Rick Young, and he was working with a colleague at Boston Children's Hospital, Lenson, and they noticed that there was this group of so-called regRNAs. These were non-coding regions that historically have been really ignored. And as they looked and explored their function further, what they discovered was that, in fact, these regRNA elements play a critical role in controlling how much protein is produced. And so the story of CAMP4 has been to continue to understand and map different cell lines so that we could take a particular target gene and, by using tools or established medicines, for example, like antisense oligonucleotides, we could actually increase the amount of a gene's protein back up to normal." #CAMP4 #CAMP4Therapeutics #SYNGAP1 #CuresSYNGAP1 #regRNA #RegulatoryRNA camp4tx.com Download the transcript here

Dr. Yuri Maricich, Chief Medical Officer at CAMP4 Therapeutics, describes regulatory RNA, a new area of biology that recognizes the role of Reg RNA in the production of proteins from specific genes. This technology is well-suited for haploinsufficient diseases such as SYNGAP1-related disorders, in which there is a lack of healthy protein and both parents carry a copy of the mutated gene. The goal is to create disease-modifying treatments that correct the underlying genetic cause rather than treating the symptoms. Yuri explains, "What was really unique about CAMP4's scientific approach is that we're focused on a whole new and emerging area of biology called regulatory RNA. And these are control elements for the expression of genes. In other words, how much protein we get from a particular gene. And there's been a lot of work in the past on how to have less protein made, particularly if it's a protein that has a mutation that causes a problem. But in medicine, there have been very few opportunities to actually increase the amount of protein, but there are many diseases that need more healthy protein." "The backdrop of CAMP4 is that there was work done just over eight years ago at the Whitehead Institute at the Massachusetts Institute of Technology in a lab by Rick Young, and he was working with a colleague at Boston Children's Hospital, Lenson, and they noticed that there was this group of so-called regRNAs. These were non-coding regions that historically have been really ignored. And as they looked and explored their function further, what they discovered was that, in fact, these regRNA elements play a critical role in controlling how much protein is produced. And so the story of CAMP4 has been to continue to understand and map different cell lines so that we could take a particular target gene and, by using tools or established medicines, for example, like antisense oligonucleotides, we could actually increase the amount of a gene's protein back up to normal." #CAMP4 #CAMP4Therapeutics #SYNGAP1 #CuresSYNGAP1 #regRNA #RegulatoryRNA camp4tx.com Listen to the podcast here

This week, I'm joined by Dr. Felice Chan, a Chinese medicine doctor who bridges Eastern and Western approaches to healing after years studying allopathic medicine including shadowing an oncology neurosurgeon and working at Boston Children's Hospital. We dive into the fascinating contrasts between healthcare in Hong Kong and the U.S., the 5,000-year misunderstanding around acupuncture, and how our gut health connects to anxiety, depression, and even our skin. Dr. Chan shares practical, science-backed tips to reduce bloating, support digestion, curb sugar cravings, and shift your mindset around food—plus her honest takes on popular health trends like intermittent fasting and cold plunging. We also get into cosmetic acupuncture, what not to do on your period, how emotions manifest physically, and how to “eat your skincare” by nourishing your blood and creating a vibrant, resilient body from the inside out.This episode is brought to you by:Get 20% off your order at Bakedbymelissa.com/BLONDE.Go to ProLonLife.com/BLONDE for 15% off plus a $40 bonus gift when you subscribe to their 5-day program.Visit Hungryroot.com/blonde and use code blonde for 40% off your first box.Go to fromourplace.com/BLONDE and use code BLONDE for 10% off sitewide.Get $10 off your first month's subscription and enjoy free shipping when you visit Nutrafol.com and use promo code BLONDE.Go to Quince.com/blonde for 365-day returns, plus free shipping on your order.Please note that this episode may contain paid endorsements and advertisements for products and services. Individuals on the show may have a direct or indirect financial interest in products or services referred to in this episode.Produced by Dear Media.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Dr. Juan Melero-Martin is an Associate Professor and the Endowed Chair in Cardiac Surgery at Boston Children's Hospital. His lab uses bioengineering principles to understand how vascular networks are formed and the mechanisms by which the vasculature modulates the engraftment and activity of various human stem cells.

In this World Shared Practice Forum podcast, Dr. Robinder Khemani, co-author of the PALICC-2 guidelines, discusses the real-world application of pediatric ARDS management strategies. Through a case-based conversation, Dr. Khemani shares nuanced insights on intubation timing, ventilator settings, neuromuscular blockade, and rescue therapies, including ECMO. He also introduces the REDvent trial, a novel approach to lung and diaphragm protective ventilation. This content is ideal for clinicians, respiratory therapists, and healthcare educators seeking to deepen their understanding of evidence-informed, physiology-driven care in pediatric acute respiratory distress syndrome. LEARNING OBJECTIVES - Analyze the clinical decision-making process for intubation in pediatric ARDS - Apply PEEP titration techniques to assess lung recruitability in patients with PARDS - Evaluate the role of neuromuscular blockade in maintaining lung protective ventilation - Identify appropriate advanced rescue therapies based on PARDS phenotypes - Explore the principles and outcomes of the REDvent trial in ventilator management AUTHORS Robinder "Roby" Khemani, MD, MsCI Professor of Pediatrics, Vice Chair of Research University of Southern California, Department of Anesthesiology and Critical Care Medicine Children's Hospital Los Angeles Jeffrey Burns, MD, MPH Emeritus Chief Division of Critical Care Medicine Department of Anesthesiology, Critical Care and Pain Medicine Boston Children's Hospital Professor of Anesthesia Harvard Medical School DATE Initial publication date: October 28, 2025. ARTICLE REFERENCED Khemani RG, Bhalla A, Hotz JC, et al. Randomized Trial of Lung and Diaphragm Protective Ventilation in Children. NEJM Evid. 2025;4(6):EVIDoa2400360. doi:10.1056/EVIDoa2400360 TRANSCRIPT https://cdn.bfldr.com/D6LGWP8S/at/47wbxnvxtcpvv54p48gc2v/202510_WSP_Khemani_Transcript.pdf Please visit: http://www.openpediatrics.org OPENPediatrics™ is an interactive digital learning platform for healthcare clinicians sponsored by Boston Children's Hospital and in collaboration with the World Federation of Pediatric Intensive and Critical Care Societies. It is designed to promote the exchange of knowledge between healthcare providers around the world caring for critically ill children in all resource settings. The content includes internationally recognized experts teaching the full range of topics on the care of critically ill children. All content is peer-reviewed and open-access thus at no expense to the user. For further information on how to enroll, please email: openpediatrics@childrens.harvard.edu CITATION Khemani RG, Burns JP. Practical Strategies for Management of Patients with Pediatric ARDS. 10/2025. OPENPediatrics. Online Podcast. https://soundcloud.com/openpediatrics/practical-strategies-for-management-of-patients-with-pediatric-ards-by-r-khemani-openpediatrics.

This week we take a closer look at Retinopathy of Prematurity (ROP) -  from screening and staging to treatment and long-term outcomes. Join us as we shine some light on this sight-saving topic with insights from Dr. Nimesh Patel - Assistant Professor of Ophthalmology at Harvard Medical School and the director of Pediatric Vitreoretinal Surgery at Boston Children's Hospital. You won't believe your eyes at how much there is to see in the world of ROP care!

In this episode, Press Ganey CEO Pat Ryan talks with Dr. Kevin B. Churchwell, President and CEO of Boston Children's Hospital, about building a culture of safety and trust and how transparency, a shared safety language, and daily huddles turn good intentions into measurable outcomes.This episode is sponsored by Press Ganey.

In this special Complex Care Journal Club podcast episode, co-hosts Kilby Mann, Kristie Malik, and Kathleen Huth interview presenters of posters relevant to the care of children with medical complexity at the American Academy of Pediatrics 2025 National Conference & Exhibition. Speakers describe their study findings and implications for practice. Dr. Rishi Agrawal discusses the role of the Council on Children with Disabilities in translating research into improved clinical care and advocacy for children with medical complexity. SPEAKERS Rishi Agrawal, MD, MPH Professor of Pediatrics, Northwestern University Feinberg School of Medicine, Attending Physician, Ann & Robert H. Lurie Children's Hospital of Chicago Elizabeth Avery ‌Hill, DO Assistant Professor, University of Utah‌ Michelle Melicosta, MD, MPH, MSC, Associate Chief Medical Officer, Kennedy Krieger Institute, Assistant Professor, Johns Hopkins University School of Medicine Patricia Notario, MD, Medical Director of the Pediatric Complex Care Program, Billings Clinic Prasiddha Parthasarathy, MD, Resident, University of Toronto HOSTS Kristina Malik, MD Assistant Professor of Pediatrics, University of Colorado School of Medicine Medical Director, KidStreet Pediatrician, Special Care Clinic, Children's Hospital Colorado Kilby Mann, MD Assistant Professor Pediatric Rehabilitation Medicine Children's Hospital Colorado Kathleen Huth, MD, MMSc Pediatrician, Complex Care Service, Division of General Pediatrics Boston Children's Hospital Assistant Professor of Pediatrics Harvard Medical School DATE Initial publication date: October 14, 2025. RESOURCES REFERENCED ‌Project ECHO/ECHO Model: https://projectecho.unm.edu/model/ ‌Council on Children with Disabilities (COCWD): https://www.aap.org/en/community/aap-councils/council-on-children-with-disabilities/ ‌AAP Experience National Conference Denver 2025 - Conference Schedule: https://aapexperience.org/schedule/ TRANSCRIPT https://cdn.bfldr.com/D6LGWP8S/at/m48sjfwmqfnrfwnxg8p7p88/CCJCP_2025_AAP_conference_10-13-25.pdf Clinicians across healthcare professions, advocates, researchers, and patients/families are all encouraged to engage and provide feedback! You can recommend an article for discussion using this form: https://forms.gle/Bdxb86Sw5qq1uFhW6. Please visit: http://www.openpediatrics.org OPENPediatrics™ is an interactive digital learning platform for healthcare clinicians sponsored by Boston Children's Hospital and in collaboration with the World Federation of Pediatric Intensive and Critical Care Societies. It is designed to promote the exchange of knowledge between healthcare providers around the world caring for critically ill children in all resource settings. The content includes internationally recognized experts teaching the full range of topics on the care of critically ill children. All content is peer-reviewed and open-access thus at no expense to the user. For further information on how to enroll, please email: openpediatrics@childrens.harvard.edu CITATION Mann K, Malik K, Agrawal R, Hill EA, Melicosta M, Notario P, Parthasarathy P, Huth K. Practice-Changing Research in Complex Care at the American Academy of Pediatrics Conference 2025. 10/2025. OPENPediatrics. Online Podcast. https://soundcloud.com/openpediatrics/practice-changing-research-in-complex-care-at-the-american-academy-of-pediatrics-conference-2025.

Show Notes: Scott Cole describes his initial struggles at Harvard, dropping out after freshman year, and returning multiple times before finally graduating in 2012. He  shares his first dropout experience, including a brief stint in California and a return to Harvard for sophomore year. He details his various jobs and adventures, including working at a car wash, landscaping, and a research assistant position at Harvard Forest. Working on a Ranch in Wyoming Scott thinks back to his days working at a ranch in Wyoming, where he learned cowboy skills and participated in cattle drives. He describes his move to Middlebury, Vermont, where he worked on an organic farm, a cross-country ski area, and a bakery. He also shares where he learned to cook. Back to School and on to a Law firm Scott discusses his return to Boston to finish college, working part-time at a law firm and attending school. He describes the challenges of balancing work, school, and financial aid, leading to another dropout. Scott talks about his relationship ending and moving back to California, where he worked at Sequoia National Park resort teaching cross country skiing. He quit this job to go to Guatemala with his dad's school group and spent some time there before moving to Oakhurst and working at a restaurant where he learned cooking skills. He worked there for two years until he paid off his student loans, and with his new found freedom, decided to hit the road and hike through the Sierra Mountains. He also talks about working in Fresno and in a job at the UC Cooperative Extension promoting school gardening as a way to teach nutrition education. From Alaska to Nevada Scott recounts his time working at a ranch in Alaska, teaching cross-country skiing, and working as a hiking guide and naturalist. He later moved to Boston to help a friend renovate a Victorian house and then worked with the Boston Children's Museum. After Boston, Scott describes his move to Michigan to be with a girlfriend in graduate school and working at the Maharishi Vedic University in their organic greenhouse. He also talks about his work with the Nevada Conservation Corps, cooking for a chainsaw crew, and his job at the White Mountain Research Station where he looked after a herd of sheep and cooked for the researchers. Scott finally decided to return to Harvard to finish his last six classes and talks about his experience completing his degree. Riding the Wave After completing his degree, Scott biked across the country with a friend. He reflects on his diverse experiences, including working with his hands, helping a friend who is a sculptor on building a sculpture for an exhibit. He talks about “The Table” tour working in Death Valley, and volunteering at various places, and biking in Canada from the Rockies to Bella Coola. He discusses the challenges of returning to school at an older age and the joy of completing his degree. Scott mentions his love for gardening, cooking, music, hiking, and outdoor activities, and how these hobbies filled his off-hours. Harvard Reflections An English major at Harvard, Scott mentions seeing Alan Ginsberg read at Harvard. He mentions taking a poetry class and a printing class. He also mentions Literature and Human Suffering with James Engell, Chicano Literature with visiting UCLA professor Héctor Calderón, Folklore and Mythology with Simon Bronner, a poetry class with Henri Cole, and Place, Space, and Region with Stephanie Burt.  Timestamps:  00:02: Scott Cole's Journey through Harvard and Beyond  06:36: Exploring Different Career Paths  09:41: Returning to School and Balancing Work and Education 40:07: Adventures in Alaska and Beyond  54:13: Reflecting on Life Experiences and Future Plans Links: Instagram: scootersride  Historical building preservation: Welcome to HistoriCorps - HistoriCorps Adobe restoration: cstones.orghttps://www.cstones.orgCornerstones Community  Adobe courses and home builder support:  Adobe in Actionhttps://www.adobeinaction.orgAdobe in Action Reuben Margolin art: Waves – Reuben Margolin – Kinetic Artist Science Research Station: White Mountain Research Center — Supporting scientific achievement for 75 years. Featured Non-profit: The featured non-profit of this week's episode is brought to you by Jared Eigerman who reports: “Hi. I'm Jay Eigerman, class of 1992. The featured nonprofit of this episode of The 92 Report is Street Lab. Street Lab is a nonprofit that works in neighborhoods throughout New York City to activate and improve spaces, including pedestrian streets, at no cost to the public. I've been a board member since 2011 when they first started in Boston. I especially like the street lab sales programming kits at reasonable cost so others around the world can deploy them on their own. Please take a look at streetlab.org. Now here is Will Bachman with this week's episode.” To learn more about their work, visit: streetlab.org.

In this podcast, JPEN Editor-in-Chief Dr. Kenneth Christopher, interviews Carly Milliren from the Biostatistics and Research Design Center at Boston Children's Hospital. Carly Milliren is a health services researcher primarily in pediatrics with a specific focus on eating disorders. Carly Milliren is first author of the research article “Identifying enteral nutrition using administrative data in pediatrics patients with eating disorders: A development and validation study”. Business Corporate by Alex Menco | alexmenco.net Music promoted by www.free-stock-music.com Creative Commons Attribution 3.0 Unported License creativecommons.org/licenses/by/3.0/deed.en_US October 2025

  AZ Bio Week & Life Sciences Innovation w/ Joan Koerber-Walker - AZ TRT S06 EP19 (281) 10-12-2025   Things We Learned This Week AZ Bio mission to improve life and bioscience, & make AZ a Top Ten Bioscience state AZ Bio Week 2025 - Oct. - 5 Days Talks, Events & Awards AZ Advances - nonprofit donation to biotech startups Aqualung Therapeutics is treating inflammation in the lungs, get people off ventilators & save lives Calviri is working on a Vaccine to PREVENT Cancer, currently largest animal clinical trial Anuncia Medical has a Re-Flow product to help drain fluid from the brain, treats Hydrocephalus     Guest: Joan Koerber-Walker President and CEO, AZBio - Arizona Bioindustry Association, Inc. Chairman, Opportunity Through Entrepreneurship Foundation   LKIN: https://www.linkedin.com/in/joankoerberwalker  www.azbio.org Bio: As President and CEO of AZBio, Joan Koerber-Walker works on behalf of the Arizona Bioscience and Medical Technology Industry to support the growth of the industry, its members and our community on the local and national level. Ms. Koerber-Walker is also a life science investor and has served on the boards of numerous for-profit and non-profit organizations. In the life science industry, Ms. Koerber-Walker serves as as Arizona's representative to the State Medical Technology Alliance (SMTA), a consortium of state and regional trade associations representing their local medical technology companies which she chaired in 2015 and  represents Arizona as a member of the Council of State Bioscience Associations (CSBA) and the Coalition of State Bioscience Institutes (CSBI). Active in the entrepreneurial and investment communities, she also serves as Chairman of the Board of the Opportunity Through Entrepreneurship Foundation which provides entrepreneurial education, mentoring and support to at-risk members of the community, on the Board of Advisors to CellTrust, Inc. which provides secure communication technology to the healthcare industry, and as Chairman of CorePurpose, Inc. which she founded in 2002. Ms. Koerber-Walker has been recognized as Executive of the Year by the Arizona Society of Association Executives, as a “Most Admired Leader” by the Phoenix Business Journal (2015),  in the pages of AZ Business Leaders (2013 thru 2020), Most Influential Women in Arizona Business (2014) and is a 2 time National Finalist for the Stevie Award which recognizes the work of women in business. Her past experience includes two years as the CEO of ASBA (the Arizona Small Business Association), service as a member of the Board of Trustees of the National Small Business Association in Washington D.C., President of the National Speakers Association/Arizona, Chair of the Board of Advisors to Parenting Arizona, the state's largest child abuse prevention organization, & much more.         AZBio:  Supporting Arizona's Life Science Industry for 19 Years (2003 – 2022) Learn more about Arizona's bioindustry: www.azbio.org | Facebook: AZBIO |Twitter: @AZBio @AZBioCEO We're part of a movement to create sustainable funding for life science innovation in Arizona. Learn more at www.AZAdvances.org  MOVING LIFE SCIENCE INNOVATIONS ALONG THE PATH FROM DISCOVERY TO DEVELOPMENT TO DELIVERY OUR VISION OF THE FUTURE: Arizona is a top-ten life science state. OUR MISSION: AZBio supports the needs of Arizona's growing life science ecosystem. The Arizona Bioindustry Association (AZBio) is a not-for-profit, 501(c)6 trade association supporting the growth of Arizona's life science sector. AZBio  Member Organizations in the fields of business, research and education, health care delivery, economic development, government, and other professions involved in the biosciences are the key drivers of the growth of Arizona's life science sector.  As the unified voice of our industry in Arizona, AZBio strives to make Arizona a place where bioscience organizations can grow and succeed.   AZBio works nationally and globally with the Advanced Medical Technology Association (AdvaMed), the Biotechnology Innovation Organization (BIO), the Medical Device Manufacturers Association (MDMA), the Pharmaceutical Research and Manufacturers of America (PhRMA), and leading patient advocacy organizations. Through these relationships, AZBio has access to information, contacts, resources, cost saving programs, and the global bioscience and medtech community.   Arizona's bioscience industry is growing rapidly and reached nearly 30,000 jobs spanning 2,160 business establishments in 2018. Industry employment has grown by 15 percent since 2016—twice the growth rate of the nation—with each of the five major subsectors adding jobs during the period. Arizona's universities conducted nearly $580 million in R&D activities in bioscience-related fields in 2018, fueled in part by steadily increasing NIH awards to Arizona institutions since 2016. Venture capital investments in Arizona bioscience companies increased in 2019, and during the 2016-19 period totaled $349 million. Arizona inventors have been awarded 2,178 bioscience-related patents since 2016, among the second quintile of states in patent activity.   Notes:   Seg 1   Biotech and life sciences industry in Arizona, has 3000 businesses and 36,000 employees. The economic impact in 2021 was $38.5 billion. AZ Bio would like to double, so by 2033, the impact would be $78 billion.   Examples of biotech companies in Arizona are Medtronic that makes medical devices, WL Gore, material sciences. Other companies in diagnostics, there are Sonoran Quest which does testing. This also Castle Bio Sciences, deals in cancer treatment. Some medicine companies are Bristol, Myers, and Calvari who deals in cancer drugs. Calvari is the bio science company of the year in 2024.   AZ Bio Science Week started in 2017. AZ Bio week starts Oct. 13 (2025) and has events daily from Monday to Friday.     Example of one of the many companies involved with AZ Bio week:   CND Life Sciences - CND's Syn-One Test® offers physicians and patients an accurate, convenient, evidence-based tool to help diagnose a synucleinopathy. And our mission has just begun.   NIH - National Institute of Health gives grants or funding to universities, hospitals and even companies for medical research.   Takes time to build a medical device type product, a few years to decades.   Government is an important partner, that provides financial support. Examples are Medicare research, workforce help, and tax breaks. Many organizations like this are publicly funded with government and university help.  $25 billion in funding over the last 20 years in Arizona in bio investment. Government funded $5 billion, that's from state and federal sales tax at a penny per. $112 million funding to universities in 2022. Combination of industry, government and philanthropy. Discovery phase - university helps develop the IP and research. Technology is spun out of the university to corporate development by companies. The AZ Board of Regents owns the patents. They license the patents to companies. Then you have regulatory.  Distribution of a product. Successful products are profitable. They have a royalty that pays to the company, the university and the government. Example of this was the University of Florida created Gatorade in the 1970s and still gets royalties today. Process takes 10 to 15 years, with hundreds of people involved. Clinical trials of any type of drug takes years.   Creation of the Covid vaccine was an outlier, as many people had Covid at the time so it was very easy to put together big study groups       Seg 2   Examples of newer companies in biotech field –   Neo clinical stage company dealing in heart health with aortic artery for the abdomen.   Another new company is prim dealing in MCT deficiency, compound growth and they are in clinical and testing stages.   Drugs get tested through computer models, and then on animals. Always have to worry about safety and ethics. FDA has very strict rules. You do not put people at risk, after monitor, during test and post monitoring. There's high-level quality control.       AZ Bio has members that are in the bioscience industry with current companies   AZ Advances is about bio startups in early stage companies It's a 501 C nonprofit charity that is funding, internships, and education   Patient is not only the client, but the purpose for why biotech companies exist     Neuralink Corp. is an American neurotechnology company that has developed as of 2024 implantable brain–computer interfaces. It was founded by Elon Musk and a team of eight scientists and engineers. Neuralink was launched in 2016 and first publicly reported in March 2017.   Neuralink's first human patient, Noland Arbaugh, is an Arizona native who received his implant in January 2024 at the Barrow Neurological Institute in Phoenix. He will appear at Arizona Bioscience Week 2025     https://www.azbio.org/azbw2025     Events Summary:   Monday - Women in Biotech Leading Women: Biotech & Beyond Join us for an evening of conversation and connections with our community's leading women as we kick off Arizona Bioscience Week in style!   Tuesday - Fundraising Fundraising Strategies for Life Science Startups  A compelling narrative is crucial when you are fundraising and communicating with life science investors.  This Life Science Nation (LSN) Global Fundraising Bootcamp covers topics related to executing a successful fundraise for your startup.      Wednesday – AZ Bio awards, philanthropy, entertainment, and AZ Advances The 21st Annual AZBio Awards & AZAdvances After Party Celebrate with the Educators, Researchers, and Organizations that are making life better for people in Arizona and around the world.  Join us at the Phoenix Convention Center as we honor the 2024 AZBio Award Winners. Hundreds of health innovators and business leaders will be celebrating at the 20th Annual AZBio Awards.   Thursday -  AZAdvances   AZ Advances Health Innovation Summit This exclusive event will bring together health innovation leaders to share how are moving Arizona forward as we make life better for the people we serve.   AZ Advances: Arizonans are advancing life changing and life saving innovations along the path from discovery to development to delivery. AZAdvances is developing the funding that will help advance health innovations in Arizona today and for generations to come.  Charitable donations to the AZAdvances fund at the Opportunity Through Entrepreneurship Foundation, an Arizona based 501c3 public charity, are a way to support the creation of tomorrow's medical innovations.    Friday - Voice of the Patient Patients are the reason we do what we do.  Join the conversation on life science innovation from the patient perspective.        Seg. 3 Best of AZ Bio clips:   AZ Bio & Life Sciences Innovation w/ Joan Koerber-Walker - BRT S04 EP10 (172) 3-5-2023   Guest: Joan Koerber-Walker President and CEO, AZBio - Arizona Bioindustry Association, Inc. Chairman, Opportunity Through Entrepreneurship Foundation   Full Show: HERE     Guest: Stan Miele President & CBO Aqualung Therapeutics Corp LKIN: HERE www.aqualungtherapeutics.com   Stan Miele Bio: A recognized global executive with success in sales, marketing and P&L leadership in the pharmaceutical/medical device and biotech industries. Mr. Miele was formally the Chief Commercial Officer at bioLytical Laboratories and Sucampo Pharmaceuticals Inc.  He was also President of Sucampo Pharma Americas for 6 years.   He was instrumental on some key licensing agreements for Sucampo, inclusive of the agreement with Abbott Japan, and also Takeda Pharmaceuticals (now Shire).  He is actively part of the team ensuring proper execution of clinical development, manufacturing, licensing, capital funding, alliances, and ensuring Aqualung meets all critical milestones.  He will be helping the company move toward accelerating the pipeline/platform technology and moving eNamptor™ toward commercialization.   Aqualung Therapeutics  Aqualung Therapeutics (ALT) is developing multi-pronged strategies to address the development of severe lung inflammation which is essential to the severity and outcomes of acute and chronic lung disorders such as acute lung injury, ventilator-induced lung injury (VILI), idiopathic pulmonary fibrosis, and pulmonary hypertension. Effective FDA-approved drugs are either currently unavailable or extraordinarily modest in their ability to modify disease progression. No drug is currently available that is preventive or curative. Aqualung's strategies, which include deployment of a human monoclonal antibody which targets a novel inflammatory mediator (nicotinamide phosphoribosyltransferase or NAMPT) will address the unmet need for novel, effective therapies for VILI, IPF, and pulmonary hypertension.   Full Show: HERE       Seg. 4 – Clips from:  Preventing Cancer with a Vaccine w/ Stephen Johnston of Calviri  - BRT S04 EP17 (179) 4-23-2023   Guest: Stephen Johnston Founding CEO, Calviri Inc.  LKIN: HERE https://calviri.com/   Bio: Chief Executive Officer & Chairman of the Board Stephen Albert Johnston is the inventor of the Calviri's central technologies. In addition to Calviri, he has been a founder of Eliance, Inc. (Macrogenics), Synbody Biotechnology and HealthTell, Inc. He is Director of the Arizona State University Biodesign Institute's Center for Innovations in Medicine and Professor in the School of Life Sciences. He has published almost 200 peer-reviewed papers and holds 45 patents. Prior to his appointment at ASU he was Professor and Director of the Center for Biomedical Inventions at UT-Southwestern Medical Center and Professor of Biology and Biomedical Engineering at Duke University. He is a member of the National Academy of Inventors. Dr. Johnston received his B.S. and Ph.D. degrees from the University of Wisconsin.     Calviri Inc.  We are determined to offer humanity a better life, free from cancer. While our goal is hugely ambitious, we are intensely driven to rid the planet of worry from cancer. Calviri's mission is to provide affordable products worldwide that will end deaths from cancer. We are a fully integrated healthcare company developing a broad spectrum of vaccines and companion diagnostics that prevent and treat cancer for those either at risk or diagnosed. We focus on using frameshift neoantigens derived from errors in RNA processing to provide pioneering products against cancer. The company is a spin out of the Biodesign Institute, Arizona State University, located in Phoenix, AZ. We have the largest dog vaccine trial in the world underway at three premier veterinary universities. The five-year trial will assess the performance of a preventative cancer vaccine.   Full Show: HERE       ReFlow to Help Treat Hydrocephalus w/ Elsa Abruzzo & Mark Geiger of Anuncia Medical - BRT S04 EP23 (186) 6-11-2023     Guest: Elsa Chi Abruzzo RAC, FRAPS – President Elsa Chi Abruzzo is a medical device executive, entrepreneur, and a founding member of Anuncia, Inc., Alcyone Therapeutics, Arthromeda, Inc. and Cygnus Regulatory. Elsa has a 30+ year successful product development, operations, regulatory, quality, and clinical track record in med tech Industries. Her experience includes leadership positions at Baxter, Cordis JNJ, CryoLife, Percutaneous Valve Technologies, AtriCure, InnerPulse, Merlin MD, Sapheon, and PTS Diagnostics. Elsa earned a BS in engineering from the University of Miami in Coral Gables, FL and is regulatory affairs certified and a Regulatory Affairs Professional Society Fellow, recognized for her leadership in Regulatory and Quality by MDDI.   https://anunciamedical.com/the-anuncia-story/#team https://www.linkedin.com/in/elsachiabruzzo/   https://anunciamedical.com/ About Anuncia Conceptualized in 2014 in collaboration with Boston Children's Hospital and spun out of Alcyone Therapeutics in 2018, Anuncia's patented portfolio of technologies are intended to provide peace-of-mind through innovation. Our core ReFlow™ technology uses a simple finger depression of a soft silicone dome located under the patient's scalp to produce a noninvasive, one-way flush of the patient's own CSF directed toward the ReFlow™ catheter to restore or increase CSF flow through a non-flowing shunt and potentially avoid emergency surgery.  Learn More     The name Anuncia comes from Panthera Uncia, the species name of the snow leopard. These animals live in mountainous regions of Asia and have been called by the World Wildlife Foundation “Guardians of the Headwaters” as they roam the headwater areas of the western basins. The origin of the word hydrocephalus comes from the Greek hudrokephalon, from hudro ‘water'+ kephalē ‘head'. The snow leopard, or Guardian of the Headwaters, is a symbol of Anuncia's dedication to improve daily quality of life for the millions of underserved patients with hydrocephalus and other CSF disorders, as well as their families, who suffer from the clinical, economic, and emotional burden of repeat revision brain surgery due to VP shunt occlusions.      Full Show: HERE           Best of Biotech from AZ Bio & Life Sciences to Jellatech: HERE   Biotech Shows: HERE   AZ Tech Council Shows:  https://brt-show.libsyn.com/size/5/?search=az+tech+council *Includes Best of AZ Tech Council show from 2/12/2023      ‘Best Of' Topic: https://brt-show.libsyn.com/category/Best+of+BRT      Thanks for Listening. Please Subscribe to the BRT Podcast.     AZ Tech Roundtable 2.0 with Matt Battaglia The show where Entrepreneurs, Top Executives, Founders, and Investors come to share insights about the future of business.  AZ TRT 2.0 looks at the new trends in business, & how classic industries are evolving.  Common Topics Discussed: Startups, Founders, Funds & Venture Capital, Business, Entrepreneurship, Biotech, Blockchain / Crypto, Executive Comp, Investing, Stocks, Real Estate + Alternative Investments, and more…    AZ TRT Podcast Home Page: http://aztrtshow.com/ ‘Best Of' AZ TRT Podcast: Click Here Podcast on Google: Click Here Podcast on Spotify: Click Here                    More Info: https://www.economicknight.com/azpodcast/ KFNX Info: https://1100kfnx.com/weekend-featured-shows/     Disclaimer: The views and opinions expressed in this program are those of the Hosts, Guests and Speakers, and do not necessarily reflect the views or positions of any entities they represent (or affiliates, members, managers, employees or partners), or any Station, Podcast Platform, Website or Social Media that this show may air on. All information provided is for educational and entertainment purposes. Nothing said on this program should be considered advice or recommendations in: business, legal, real estate, crypto, tax accounting, investment, etc. Always seek the advice of a professional in all business ventures, including but not limited to: investments, tax, loans, legal, accounting, real estate, crypto, contracts, sales, marketing, other business arrangements, etc.

Dr. Carole Keim welcomes neonatologist and chair of pediatrics at Tufts Medical Center, Dr. Geoff Binney, MD, MPH, to The Baby Manual for a conversation about what expectant parents should know regarding newborn care and the NICU, the Neonatal Intensive Care Unit. Drs. Keim and Binney discuss the age of viability for premature babies, advances in neonatology such as surfactant therapy for Respiratory Distress Syndrome, and the different levels of NICU care available depending on gestational age and medical needs.Dr. Binney and Dr. Keim talk about common newborn challenges, including breathing difficulties, infections, blood sugar monitoring for at-risk infants, and jaundice. Both doctors stress the importance of preventive care, such as antibiotics for Group B strep and vitamin K injections at birth. Dr. Binney shares that a neonatologist's role is to provide a supportive environment for premature or ill infants so they can continue developing safely. He reassures parents that most children born early grow up healthy and indistinguishable from their peers. This episode gives parents-to-be information about what to expect if their child is born preterm and offers them comfort in knowing how far medical care for newborn infants has come. Dr. Geoff Binney, MD, MPH:Dr. Geoffrey Binney is a neonatologist in Boston, Massachusetts and is affiliated with multiple hospitals in the area, including Boston Children's Hospital and Tufts Medical Center. He is the Chair and David And Leona F. Karp Professor of Pediatrics, and the Tufts University School of Medicine Pediatrician-in-Chief. He received his medical degree from the University of California, San Diego School of Medicine and has been in practice for more than 20 years.__ Resources discussed in this episode:The Holistic Mamas Handbook is available on AmazonThe Baby Manual is also available on Amazon__Contact Dr. Carole Keim, MDlinktree | tiktok | instagramContact Dr. Geoff Binney, MD, MPHBoston Children's Hospital | Tufts Medicine | linktree Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

part one:  Dua Hassan is a physician at Boston Children's Hospital and a former clinical instructor at Stanford University School of Medicine. I'm a Pediatrician. Here's What I Tell Parents When They Bring Me RFK Jr.'s Claims.Fact checking doesn't work.part two: Arthur “Art” Jipson is an Associate Professor of Sociology in the Department of Sociology, Anthropology, and Social Work at the University of Dayton. Right-wing extremist violence is more frequent and more deadly than left-wing violence − what the data shows 

Is the "best" hospital just about technology and surgical success? Ben Harder, the journalist who oversees the methodology and data for the U.S. News Best Children's Hospitals Rankings (2025), joins Katie to break down what truly defines quality in pediatric care. Ben shares his deeply personal family story—a tragedy 50 years in the past that drives his commitment to making data-driven information accessible today. This episode is a crucial guide for parents, explaining the three core pillars of the rankings: structure/resources, processes of care, and patient outcomes. We dive into why essential human-focused services like Child Life Specialists, chaplains, and family advisory boards are included in the scorecard and how they influence the rankings. Ben illuminates the challenge faced by these vital "cost centers" in a revenue-driven healthcare system, and offers a powerful message: parents are the strongest possible advocates for their children, and they should use every resource available—including the U.S. News data—to make informed, collaborative choices for their child's care team. Guest Links U.S. News Best Children's Hospitals Rankings: All data is freely available for families to research hospitals by region and specialty. Website: US News Press Release Episode Highlights & Key Takeaways The Personal Motivation: Ben shares the heartbreaking story of his cousin, whose permanent brain injury after a heart surgery complication 50 years ago lacked the complete care team needed to ensure a good outcome—a void the U.S. News data is designed to fill today. The Three Pillars of Ranking: US News analyzes over 1,000 data points grouped into: 1) Resources/Structure (nurses, expertise, technology, child life services), 2) Processes of Care (following best practices, infection control), and 3) Outcomes (survival, length of stay, quality of life). The Honor Roll: The 2025 Honor Roll features the top 10 hospitals recognized for high performance across multiple specialties, including: Boston Children's Hospital, The Children's Hospital of Philadelphia (CHOP), Cincinnati Children's, Texas Children's Hospital, and others. A Piece of the Puzzle: The rankings are one resource to use alongside insurance coverage, geographic location, and most importantly, consulting your child's doctors and trusting your parental intuition. The Value of Human Support: Services like Child Life Specialists, support groups, and family advisory boards are included in the structural data points, serving as a motivator for hospitals to invest in comprehensive, family-centered care. Advocacy is Essential: Ben gives parents permission to advocate relentlessly, reminding them they know their child best. Collaborating with—not simply questioning—the care team can be life-saving. Chapters: Timestamp Topic 0:00 Ben Harder's Personal Connection to Hospital Rankings 1:03 The Official Launch of the U.S. News Best Children's Hospitals 2025 3:20 US News Honor Roll: The Top 10 Children's Hospitals 4:26 FREE COURSE Ad: Shots, Blood Draws & Comfort Positioning 5:35 Meet Ben Harder: Journalist, Father, and Best Hospitals Lead 7:59 The 3 Pillars of US News Ranking Methodology (1000+ Data Points) 11:37 The Role of Expert Work Groups in Defining Data 13:58 The Future of Family Expertise in Shaping Rankings 16:59 How Families Should Use the U.S. News Rankings 21:09 Why Child Life Services and Support Resources Matter in Rankings 25:12 Why Support Services are Overlooked: Revenue vs. Cost Centers 27:54 Ben Harder's Personal Story: The Tragic Need for Comprehensive Care 31:00 The Efficacy and Impact of Child Life Specialists 34:36 What Families Should Expect and Ask For: Advocacy Permission 38:23 Where to Find the U.S. News Best Children's Hospitals Rankings 38:58 Disclaimer   Resources for You 1. Unlock Two FREE Courses (Value $250+) We want to equip you to better support your child during medical experiences! Get our popular courses "How to Prepare, Support, and Respond to Your Child During Shots, Blood Draws, and Vaccines" AND "How to Use Comfort Positioning in Pediatrics" completely free. How to Get It: Leave a written review for the Child Life On Call podcast on Apple Podcasts or Spotify. Take a quick screenshot of your submitted review. Email the screenshot to: podcast@childlifeoncall.com 2. Connect with Child Life On Call Website: ChildLifeOnCall.com Instagram: @ChildLifeOnCall Disclaimer: The content of this podcast is for informational purposes only. The host and guests are not licensed therapists or medical doctors. Always consult with your child's qualified medical professional for advice specific to your family's situation.  

This week we review a recent multicenter, randomized trial pitting 2 different immunosuppressive therapeutic approaches against each other. How did a novel approach of everolimus + low dose tacrolimus compare to more standard MMF + standard, higher dose tacrolimus in avoidance of major adverse transplant events or complications? How did this first ever prospective trial in the pediatric heart transplantation world start and how difficult was it to perform in the absence of corporate or NIH support? Why can these data help inform FDA labelling for this novel approach and why is this important? Dr. Kevin Daly of Boston Children's Hospital shares his deep insights into this work this week!DOI: 10.1001/jama.2025.14338

Osteosarcoma Webinar Series: Alanna Church, MD, Associate Director, Laboratory for Molecular Pediatric Pathology at Boston Children's Hospital, Assistant Professor of Pathology at Harvard Medical School, and Conference Cochair joins us on OsteoBites to discuss insights and higlights from the AACR Special Conference in Cancer Research: Discovery and Innovation in Pediatric Cancer—From Biology to Breakthrough Therapies, September 25-28 in Boston.Dr. Church is currently a Molecular and Pediatric Pathologist at Boston Children's Hospital, where she is a founder and associate medical director of the Laboratory for Molecular Pediatric Pathology (LaMPP). She is an Assistant Professor of Pathology at Harvard Medical School, the Program Director for the Harvard Molecular Genetic Pathology Fellowship, and the incoming Chair of Clinical Practice for the Association for Molecular Pathology. Her clinical and research work focuses on bringing molecular testing to the clinical care of children with cancer. Through institutional projects (the Profile study, GAIN consortium study), she has profiled thousands of children's tumors and has used these results to make real-time impacts on their diagnoses and treatments. She is involved in national initiatives to improve the quality and access to molecular testing for children with cancer, including the NCI-funded Count Me In Study (Dana Farber, Broad Institute), the National Comprehensive Cancer Network, the National Institutes of Health, and the Children's Oncology Group.

All about gymnastics! We interview Dr. Elspeth Hart from Boston Children's on her latest article on Gymnastics Medicine and what to look out for when treating gymnasts in the orthopedic setting. We also highlight recent articles on the urgency of stable SCFE, a lesser-known method for pinning supracondylar humerus fractures, and short versus long leg casting for distal tibia physeal fractures. Your hosts are Tyler McDonald (University of South Alabama), and Stephanie Logterman (Arnold Palmer Hospital for Children), Josh Holt (University of Iowa), and Carter Clement (Manning Family Children's in New Orleans). Music by A. A. Aalto. Gymnastics Upper Extremity Article mentioned: Hart E, Bauer AS, Bae DS. Common upper extremity gymnastics injuries and gymnastic specific return to play protocols. J Pediatr Soc North Am. 2024 Feb 28;6:100016. doi: 10.1016/j.jposna.2024.100016. PMID: 40433250; PMCID: PMC12088353. Link to the non profit Gymnastics Medicine: Education and Research: GymnasticsMedicine.org Link to learn more about the 7th annual Gymnastics Medicine Symposium (use code "Gym15" to save 15% if interested in signing up!): Symposium 2025 - Gymnastics Medicine   References: 1. Hart E, Bair K, Broz J, Griffith K, Herrera-Set A, Lattimore D, Melvin E, Sweeney E. Gymnastics Medicine: A New Subspecialty in Sports Medicine. Curr Sports Med Rep. 2025 May 1;24(5):126-134. doi: 10.1249/JSR.0000000000001249. PMID: 40323057. 2. White AB, Keil LG, Bardsley H, Selberg C, Mansour A, Brooks AC, Manickam R, Mayassi HA, Zhao L, Uchtman M, Whitlock P, Stone J. How Urgent Are Stable SCFEs? A Multisite Retrospective Study of Surgical Timing and Complications Among Patients With Stable Slipped Capital Femoral Epiphysis. J Pediatr Orthop. 2025 Sep 1;45(8):485-491. doi: 10.1097/BPO.0000000000002997. Epub 2025 May 1. PMID: 40314216. 3. Grewal RS, Kitchen BT, Bomar JD, Cidambi EO, Dexter MJ, Edmonds EW, Pring ME, Upasani VV, Wallace CD, Pennock A. Displaced Distal Tibia Physeal Fractures: Short Leg Versus Long Leg Casting-A Prospective Study. J Pediatr Orthop. 2025 Aug 1;45(7):e614-e617. doi: 10.1097/BPO.0000000000002961. Epub 2025 Apr 7. PMID: 40191914. 4. Muto S, Niwa S, Fujihara Y, Ota H, Kumagai H. Comparative Analysis of Postoperative Rotational Malalignment in Pediatric Supracondylar Humerus Fractures: Cross Pinning Versus Lateral Para-olecranon Pinning. J Pediatr Orthop. 2025 Sep 1;45(8):458-465. doi: 10.1097/BPO.0000000000003000. Epub 2025 May 5. PMID: 40323798.

In this episode, Dr. Robert Insoft, Neonatologist and Chief Operating Officer at Franciscan Children's Campus, Boston Children's Hospital System, shares his perspective on guiding teams through healthcare integrations, prioritizing staff engagement, and evolving as a leader to ensure high quality patient care.

In this episode, Dr. Robert Insoft, Neonatologist and Chief Operating Officer at Franciscan Children's Campus, Boston Children's Hospital System, shares his perspective on guiding teams through healthcare integrations, prioritizing staff engagement, and evolving as a leader to ensure high quality patient care.

On today's episode we're focusing on the management of borderline hip dysplasia with Dr. Travis Matheney, a pediatric orthopedic surgeon at Boston Children's Hospital. We have some great articles for you that contribute well to our conversation on the treatment options for borderline hip dysplasia. We'll start off our discussion today with an article titled “Periacetabular Osteotomy Improves Pain and Function in Patients With Lateral Center-edge Angle Between 18° and 25°, but Are These Hips Really Borderline Dysplastic?” Dr. Michael McClincy and team at Boston Children's Hospital concluded that patients with a lateral center edge angles of 18-25 frequently have other radiographic features of dysplasia suggestive of abnormal femoral head coverage by the acetabulum and that these hips may be inappropriately labeled as “borderline” or “mild” dysplasia.  The authors recommended a more thorough radiographic evaluation of the patient with suspected dysplasia, including measurement of the Tonnis angle, FEAR index, anterior and posterior wall index, and anterior center edge angle.We are joined today by Dr. Travis Matheney, an Assistant Professor of orthopedic surgery at Harvard Medical School and pediatric orthopedic surgeon at Boston Children's Hospital.  He has a particular interest in pediatric hip pathology and is part of the Child & Young Adult Hip Preservation program at Boston Children's. Dr. Matheney trained Ashley and I during our residency at Harvard, so we're very excited to have him join us today and share his wisdom on this controversial topic.

In this World Shared Practice Forum Podcast, Dr. Kathryn Maitland discusses the findings of the GASTROSAM trial, which investigates the safety and efficacy of intravenous rehydration for children with severe acute malnutrition and gastroenteritis. The trial explores the effectiveness of intravenous fluids as a safe alternative to current rehydration guidelines for malnourished children. Dr. Maitland reviews the trial's design, key outcomes, and implications for clinical practice, providing valuable insights for healthcare professionals involved in pediatric care in resource-limited settings. LEARNING OBJECTIVES - Understand the key findings of the GASTROSAM trial and their implications for rehydration practices in children with severe acute malnutrition. - Identify the challenges and limitations of current rehydration guidelines for malnourished children in resource-limited settings. - Discuss the safety concerns associated with intravenous rehydration and how the GASTROSAM trial addresses these issues. - Explore the importance of simplifying the rehydration guidelines for children in resource-limited settings AUTHORS Kathryn Maitland, FMedSc, OBE Professor of Tropical Paediatric Infectious Disease Department of Surgery & Cancer Faculty of Medicine Director of ICCARE Centre at the Institute for Global Health Innovation, Imperial College, London Jeffrey Burns, MD, MPH Emeritus Chief Division of Critical Care Medicine Department of Anesthesiology, Critical Care and Pain Medicine Boston Children's Hospital Professor of Anesthesia Harvard Medical School DATE Initial publication date: September 22, 2025. ARTICLES REFERENCED - Maitland K, Ouattara SM, Sainna H, et al. Intravenous Rehydration for Severe Acute Malnutrition with Gastroenteritis. N Engl J Med. Published online June 13, 2025. doi:10.1056/NEJMoa2505752 - Maitland K, Kiguli S, Opoka RO, et al. Mortality after fluid bolus in African children with severe infection. N Engl J Med. 2011;364(26):2483-2495. doi:10.1056/NEJMoa1101549 - Brent B, Obonyo N, Akech S, et al. Assessment of Myocardial Function in Kenyan Children With Severe, Acute Malnutrition: The Cardiac Physiology in Malnutrition (CAPMAL) Study. JAMA Netw Open. 2019;2(3):e191054. Published 2019 Mar 1. doi:10.1001/jamanetworkopen.2019.1054 TRANSCRIPT https://cdn.bfldr.com/D6LGWP8S/at/xvv7vchn4skmc6m6wv25xfw/UPDATED_202509_WSP_Maitland_Transcript.pdf Please visit: http://www.openpediatrics.org OPENPediatrics™ is an interactive digital learning platform for healthcare clinicians sponsored by Boston Children's Hospital and in collaboration with the World Federation of Pediatric Intensive and Critical Care Societies. It is designed to promote the exchange of knowledge between healthcare providers around the world caring for critically ill children in all resource settings. The content includes internationally recognized experts teaching the full range of topics on the care of critically ill children. All content is peer-reviewed and open-access thus at no expense to the user. For further information on how to enroll, please email: openpediatrics@childrens.harvard.edu CITATION Maitland K, Burns JP. GASTROSAM Key Insights: Safe Rehydration for Malnourished Children. 09/2025. OPENPediatrics. Online Podcast. https://soundcloud.com/openpediatrics/gastrosam-key-insights-safe-rehydration-for-malnourished-children-by-k-maitland-openpediatrics.

Our speaker is my good friend Ofer Levy who is a Professor of Pediatrics at Harvard Medical School and the Director of Precision Vaccines at Boston Children's Hospital. We will discuss the current controversy over vaccines that has escalated since COVID. I am also including excerpts from a previous podcast with Paul Mango who ran Operation Warp Speed for Trump in his first administration that successfully got a working vaccine for COVID in record time. Get full access to What Happens Next in 6 Minutes with Larry Bernstein at www.whathappensnextin6minutes.com/subscribe

This week we review a recent report from the Boston Children's team on their 39 year experience managing and caring for children with myocardial infarction following Kawasaki disease (KD). What were the clinical features of KD patients that were most associated with this rare complication? What signs or symptoms should be concerning for the caregiver of patients with KD? What are the more common approaches to the management of MI in this fragile and young patient population? Dr. Sunil Ghelani of Boston Children's Hospital offers the answers this week. DOI: 10.1016/j.jpeds.2025.114638

The race for mayor of Boston is down to Mayor Wu and Josh Kraft. Trumps homeland security chief is upping searches for illegal immigrants in Boston. In the south end of Boston, a construction worker is suffering serious injuries after a scaffolding fell off a building on Albany Street. A stop work order has been issued. A federal judge has determined that Boston Children's Hospital does not have to turn over transgender children's records or files. Cracker Barrel is going back to its original logo. Lady Gaga has added two shows to her tour in Boston. Dua Lipa has her second show in the TD Graden tonight. 

Are ultra-processed foods really the villain, or is the story more complicated? In this lively, no-nonsense conversation, endocrinologist Dr. David Ludwig (of Harvard and Boston Children's Hospital) and journalist Gary Taubes unpack why “UPF” is an enticing label but a blunt tool for science, policy, and everyday guidance.They cover:Why defining “ultra-processed” is messy, and how lumping diverse packaged foods into one bucket can mislead.How high-profile trials are interpreted (and misinterpreted), from short study durations to dropout bias and carryover effects.The role of bias and confirmation bias in nutrition research and media narratives.Where the debate should go next: moving beyond slogans toward mechanisms like how carbohydrate processing affects blood sugar and insulin.What to do in the meantime: clearer study design, healthier discourse, and pragmatic takeaways people can use now.In this conversation, you'll hear sharp disagreements, candid critiques, and concrete suggestions for doing better science. Plus a spirited back-and-forth on what “good evidence” should look like and how individuals, clinicians, and policymakers can each act on different standards of proof.What's at stake isn't academic nitpicking; it's policy decisions, headlines, and, ultimately, what lands on your plate.

In this Complex Care Journal Club podcast episode, Ms. Kathryn Knight and Dr. Brian K. Jordan discuss a national survey of families of children with medical complexity on access to home health nursing. They describe the impact of the nursing shortage on families, development of a nonprofit resource that facilitates connections between families and home nursing, and outline next steps from this work. Learn more about Hello Nurze: www.hellonurze.com Find additional details about the F.A.C.E.S. Project: www.hellonurze.com/p/faces-project SPEAKERS Kathryn Knight, BBA Co-Founder & Executive Director, Hello Nurze Brian K. Jordan, MD, PhD Associate Professor Oregon Health & Science University HOST Emily J. Goodwin, MD Clinical Associate Professor of Pediatrics University of Missouri Kansas City School of Medicine Pediatrician, General Academic Pediatrics Beacon Program Children's Mercy Kansas City DATE Initial publication date: September 8, 2025. JOURNAL CLUB ARTICLE Knight K, Knight G, Jordan BK. The Impact of the Lack of Access to Home Health Nursing on Families of Children with Medical Complexity in the United States. Home Healthc Now. 2025 Jul-Aug 01;43(4):213-220. doi: 10.1097/NHH.0000000000001356. Epub 2025 Jul 7. PMID: 40619624. OTHER ARTICLES REFERENCED Baker CD, Martin S, Thrasher J, Moore HM, Baker J, Abman SH, Gien J. A Standardized Discharge Process Decreases Length of Stay for Ventilator-Dependent Children. Pediatrics. 2016 Apr;137(4):e20150637. doi: 10.1542/peds.2015-0637. Epub 2016 Mar 10. PMID: 26966133; PMCID: PMC4811306. Hello Nurze. Connecting families and in-home nurses. Accessed August 27, 2025. https://www.hellonurze.com Moore PE, Boyer D, O'Connor MG, Baker CD, Rettig JS, Sterni L, Halbower A, Wilson KC, Thomson CC. Pediatric Chronic Home Invasive Ventilation. Ann Am Thorac Soc. 2016 Jul;13(7):1170-2. doi: 10.1513/AnnalsATS.201603-196CME. PMID: 27388405; PMCID: PMC5462000. TRANSCRIPT https://cdn.bfldr.com/D6LGWP8S/as/87x9cmw5xfnkkt74v5g5pv3/Jordan_and_Knight_Final_Transcript__9-5-25‌ Clinicians across healthcare professions, advocates, researchers, and patients/families are all encouraged to engage and provide feedback! You can recommend an article for discussion using this form: https://forms.gle/Bdxb86Sw5qq1uFhW6. Please visit: http://www.openpediatrics.org OPENPediatrics™ is an interactive digital learning platform for healthcare clinicians sponsored by Boston Children's Hospital and in collaboration with the World Federation of Pediatric Intensive and Critical Care Societies. It is designed to promote the exchange of knowledge between healthcare providers around the world caring for critically ill children in all resource settings. The content includes internationally recognized experts teaching the full range of topics on the care of critically ill children. All content is peer-reviewed and open-access thus at no expense to the user. For further information on how to enroll, please email: openpediatrics@childrens.harvard.edu CITATION Knight K, Jordan BK, Goodwin EJ. From Crisis to Connection: Matching Families with Home Nursing Support in Complex Care. 09/2025. OPENPediatrics. Online Podcast. https://soundcloud.com/openpediatrics/from-crisis-to-connection-matching-families-with-home-nursing-support-in-complex-care.

The Big Unlock · Michael Docktor, MD, Co-founder and CEO of Dock Health In this episode, Dr. Michael Docktor, Co-founder and CEO at Dock Health, shares his journey from being a pediatric gastroenterologist at Boston Children's Hospital to building a healthcare technology company. Inspired by his sister's medical experiences and his family's design background, Dr. Doctor combined medicine, design, and technology to address inefficiencies in operational workflows, particularly the administrative burdens that weigh heavily on providers and staff. Dr. Docktor explains how Dock Health was created to serve as a productivity platform for healthcare, filling the gap between electronic health records (EHRs) and the countless administrative tasks not supported by them. By digitizing and streamlining processes like referrals, patient intake, and care coordination—often still managed through faxes, emails, and spreadsheets—Dock Health aims to reduce redundancy, improve visibility, and enhance the overall user experience for healthcare organizations of all sizes. The conversation also focuses on the role of AI and automation in transforming healthcare operations. Dr. Docktor highlights Dock Health's “AI‑first” approach, incorporating generative AI and agentic models to automate routine tasks while keeping humans in the loop for oversight. He envisions a near future where administrative inefficiencies are largely eliminated, giving clinicians more time with patients. Dr. Docktor also describes AI as the “big unlock” that could massively reduce the trillions wasted annually in healthcare administration, making care more efficient, accessible, and patient‑centered. Take a listen.

NFL writer Dan Pizzuta joins the show to break down all angles of the Patriots' season opener Sunday against the Raiders. The guys discuss why this year's opener is so unpredictable and how the Pats can overcome Las Vegas on offense and defense. Later, Rhamondre Stevenson sits down for the first 4-minute drill interview of the season. ⏰EPISODE TIMELINE⏰ 0:00 Intro 0:48 Injury report 2:46 Live film reviews coming up! 3:33 Ticket auction for Boston Children's Hospital 4:51 Gametime 5:51 Dan joins the show 6:40 What is this game about? 11:52 Patriots offense vs Raiders defense 26:35 PrizePicks 27:43 Patriots defense vs Raiders offense 41:06 Predictions! 43:07 Belichick bans Patriots scouts from UNC 45:17 4-Minute Drill w/ Rhamondre Stevenson Pats Interference Podcast w/ Andrew Callahan on CLNS Media is Powered by:

Sarah Gardner is the founder of the non-profit Yoga Reaches Out, which has raised millions for Boston Children's Hospital.  She is a skilled yoga teacher who has inspired thousands with her knowledge and love for yoga.  In today's episode, we chat with her about her book “Daily JAM: 366 Meditations, Daily Enlightenment in Just a Minute.” The “Daily JAM” offers simple words of wisdom that will help you live every day with greater purpose,love, patience and awe in the magic of being human. Take it from me, it works!  Namaste…

A bonus episode in our series "Falling Behind: The Miseducation of America's Boys." Dr. Kevin Simon, attending pediatric psychiatrist at Boston Children's Hospital, shares his experience and expertise in a conversation recorded on stage at WBUR CitySpace.

Margaret Fry, MD, President and Chief Executive Officer of Boston Children's Pediatric Physicians' Organization, shares insights on the organization's current strategy and how they are leveraging technology to improve care delivery. She highlights the role of information technology, including AI scribes, and discusses approaches to addressing ongoing workforce challenges.

It's Monday, August 18th, A.D. 2025. This is The Worldview in 5 Minutes heard on 140 radio stations and at www.TheWorldview.com.  I'm Adam McManus. (Adam@TheWorldview.com) By Adam McManus Vietnamese Communists cut electricity to church mid-service As a Catholic priest quietly led a service in the home of one of 20 worshippers in the evening of August 11 in the Đại Từ district in northeast Vietnam, Communist authorities cut the home's electricity to stop the service, reports International Christian Concern. Then, they detained three church members. In John 15:18, Jesus said, “If the world hates you, keep in mind that it hated Me first.” Multiple worshippers livestreamed the arrests on Facebook. Within two hours, the video had been seen 60,000 times. After Putin-Trump meeting, Trump declared: “It's up to Zelenskyy” In a join press conference with U.S. President Donald Trump, Russian President Vladimir Putin summarized his perception of what needed to happen to end the Russo-Ukrainian War. He made the remarks following his 3-hour sit-down meeting with President Trump in Anchorage, Alaska last Friday.  Listen to the real-time translation by a female translator. PUTIN: “The situation in Ukraine has to do with fundamental threats to our security. Everything that's happening is a tragedy for us and terrible wound. Therefore, the country is sincerely interested in putting an end to it. “[At] the same time, we're convinced that in order to make the settlement lasting and long-term, we need to eliminate all the primary causes of that conflict. And we've said it multiple times, to consider all legitimate concerns of Russia and to reinstate a just balance of security in Europe and in the world on the whole. “Naturally, the security of Ukraine should be ensured as well. I would like to hope that the agreement that we've reached together will help us bring closer that goal and will pave the path towards peace in Ukraine.” Following the press conference, President Donald Trump talked to Sean Hannity on Fox News Channel. HANNITY: “If you had to grade it on a scale of one to 10?” TRUMP:  “I think the meeting was a ‘10' in the sense that we got along great. And it's good when, you know, two big powers get along, especially when they're nuclear powers. You know, we're number one, they're number two in the world.  That's a big deal. You never want to even mention that word, the word nuclear.” President Trump addressed how it went and what the next step is to bring the Russo-Ukrainian War to a close. TRUMP: “We were together almost three hours, and it was very extensive, and we agreed on a lot of points. I mean, a lot of points were agreed on, but there's not that much as you know, one or two pretty significant items, but I think they can be reached. Now, it's really up to [Ukrainian] President [Volodymyr] Zelenskyy to get it done.” Costco will not sell Abortion Kill Pill Costco Wholesale Corp. has announced it will not dispense the abortion kill pill mifepristone at its U.S. pharmacies, a decision hailed by pro-life advocates as a significant victory, reports LifeNews. The abortion kill pill has been responsible for killing millions of babies and killing and injuring countless women. The retail giant's decision comes amid pressure from Christian investors and pro-life groups urging major retailers to refrain from distributing the abortion drug. Costco has joined other major retailers like Walmart, Kroger, and Albertsons, which have also declined to sell the deadly pills. Send a 2-sentence thank you note to Ron Vachris, Costco President, 999 Lake Drive, Issaquah, Washington 98027. Massachusetts is Sanctuary state for transgender surgery on kids Massachusetts has become a “sanctuary state” for transgender procedures on children, report MassResistance. Shockingly, Massachusetts doctors who break other states' laws prohibiting transgender procedures will be protected from prosecution -- and their names hidden from the public.  While 25 states have banned such foolishness, the Massachusetts Legislature passed the so-called “shield law” on July 31, 2025. It is among the most aggressive and offensive anti-family laws anywhere in America. Days later, the state's radical lesbian Democratic Governor Maura Healy, who is in a sinful relationship with Joanna Lydgate, signed it into law. Dr. Elizabeth Boskey at Boston Children's Hospital revealed the hospital is willing to remove a 15-year-old girl's healthy breasts. BOSKEY: “The eligibility for getting gender-affirming surgeries at Boston Children's Hospital is basically the same as it would be for most other hospitals or surgeons in the United States. And that's the case because we all follow the World Professional Association for Transgender Health standards of care. “For top surgery, you are requested,  but not required, to have been on gender-affirming hormones for at least a year. If you're a ‘trans woman,' it's really encouraged that you be on estrogen for at least a year, because you want to maximize your natural breast growth. “Many surgical centers require you to be 18. At Boston Children's Hospital, for top surgeries, we'll see people as young as age 15, if they've been affirmed in their gender for a long period of time and don't really have any other life complications that make surgery inappropriate.” 41 Planned Parenthood abortion mills have closed this year Ready for some great news? So far this year, the Planned Parenthood abortion business has closed 41 centers. Despite what the abortion giant and the media would have Americans think, they all participated in abortions, reports Life News. William Carey, father of modern missions, said,  And finally, 264 years ago yesterday, a very special man was born in England. William Carey is his name and he is known as the "father of modern missions.” The eldest of five children, his parents were weavers.  Carey went to work for the local shoemaker, Thomas Old, during which time he taught himself Hebrew, Italian, Dutch, and French. He often read while working on the shoes. Carey married Old's sister-in-law, Dorothy Plackett, with whom he had seven children. Sadly, three of their kids died before the age of five. Inspired by Jonathan Edwards' An account of the life of the Rev. David Brainerd,  Carey spent 41 years in India as a missionary without a furlough.  He led 700 souls to Christ in a nation of millions.  Romans 10:15 says, “How beautiful are the feet of those who preach the good news!” He wrote a book entitled An Enquiry into the Obligations of Christians to Use Means for the Conversion of the Heathens which led to the founding of the Baptist Missionary Society. Carey was known for saying, “Expect great things from God; attempt great things for God."   He also said, "To know the will of God, we need an open Bible and an open map." He understood the importance of both Scripture and understanding the world around us. Finally, he prioritized meaningful work. He said, “I'm not afraid of failure; I'm afraid of succeeding at things that do not matter." Close And that's The Worldview on this Monday, August 18th, in the year of our Lord 2025. Follow us on X or subscribe for free by Spotify, Amazon Music, or by iTunes or email to our unique Christian newscast at www.TheWorldview.com.  I'm Adam McManus (Adam@TheWorldview.com). Seize the day for Jesus Christ.

Dozens of states are cracking down on student phone use — but is banning them completely the right call? Brinleigh Murphy-Reuter of the Digital Wellness Lab at Boston Children's Hospital joins us to explain what teens really think about phone rules in schools, how strict policies can sometimes backfire, and what parents can do to help their kids build healthy digital habits. Plus — the research on phones, mental health, and how tech companies should (or shouldn't) design for kids. Join us again for our 10-minute daily news roundups every Mon-Fri!  Learn more about our guests: https://www.theNewsWorthy.com/shownotes  Become an INSIDER for ad-free episodes: https://www.theNewsWorthy.com/insider Get The NewsWorthy MERCH here: https://www.theNewsWorthy.com/merch This episode is sponsored by  Give yourself the luxury you deserve with Quince. Go to Quince.com/newsworthy for FREE shipping on your order and 365-day returns! You can get an additional 15% off their 90-day subscription Starter Kit by going to fatty15.com/NEWSWORTHY and using code NEWSWORTHY at checkout. To advertise on our podcast, please reach out to ad-sales@libsyn.com

How did the shadowy general manager of the Oklahoma City Thunder, Sam Presti, become an urban legend? In a special NBA Finals edition of Share & Tell, Pablo unearths a treasure buried by its own elaborate design… then dances into The Jazz Rabbit Hole with Wyatt Cenac and a special mystery guest. • Make a gift to the Extraordinary Needs Fund at Boston Children's Hospital https://secure.childrenshospital.org/site/Donation2?df_id=5186&5186.donation=form1 • Listen to Branford Marsalis https://www.branfordmarsalis.com/discography/jazz Learn more about your ad choices. Visit podcastchoices.com/adchoices