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When we first dicsussed the Summer of Simulative AI in 2024 we knew it would be a brief summer, but it has recently come back with a vengeance with SimGym in April and now Simile AI's $2B Series B, backed by GreenOaks and Index Ventures with prominent backers like Fei-Fei Li and Andrej Karpathy, running tens of millions of simulations for Fortune 100 clients like CVS and 85–99% accuracy vs human focus groups. Time to catch up on why this Second Summer of simulation is working!From creating Smallville, the landmark 2023 paper on Generative Agents that showed AI characters could remember, plan, socialize, and develop emergent behaviors, to now building foundation models of human behavior, Joon Sung Park is trying to answer a much bigger question: what if we could simulate the world before making decisions in it? In this episode, the Simile co-founder and CEO joins us to unpack the path from generative agents to digital twins, why today's frontier models still fail to capture how humans actually behave, and what it would take to eventually simulate all 8 billion people on Earth.We go deep on Simile's approach to modeling human behavior: long-form interviews, observational and transaction data, randomized controlled trials, population-level and individual-level models, and post-training on the causal mechanisms behind why people make decisions. Joon explains how his research created digital twins that reproduced human behavior and attitudes 85% as accurately as people reproduced their own responses, why models optimized to be rational can be bad simulations of irrational humans, and why understanding “social physics” may require changing model weights rather than simply prompting frontier LLMs.We also explore the much larger ambition behind simulation: testing products and policies before deploying them, finding counterintuitive paths toward desired outcomes, modeling emergent behavior across entire societies, and potentially tackling problems like climate change, democratic instability, and UBI. Joon reflects on scaling laws for simulation, the economics of data-center-scale simulated worlds, the connection to Thomas Schelling and psychohistory, why simulation is surprisingly similar to painting, and whether we might already be living in one.We discuss:* How Smallville and Generative Agents led to Simile* Why Joon's team asked: “What if we can just recreate the world that we live in?”* Why useful personal agents require deep models of their users* Memory architectures, Markdown files, and the limits of prompting* “Social physics” and behavioral foundation models* Why web data captures what people say more than what they actually do* Interviews, transactions, observational data, and randomized controlled trials* Why predicting the future matters less than understanding how to shape it* How Simile creates representative simulated populations* Simulation versus prediction and the connection to Foundation's psychohistory* How to evaluate simulations instead of simply stacking LLM hallucinations* Creating digital twins of 1,000 real people and reaching 85% behavioral accuracy* Why frontier models can struggle to reproduce real human behavior* Why good simulations need to reproduce human biases and mistakes* Post-training models on randomized controlled trials* Population-level versus individual-level simulation* Scaling laws for human simulation* The long-term ambition to simulate all 8 billion people on Earth* Whether simulations could help solve climate change or detect collapsing democracy* Thomas Schelling and the history of agent-based modeling* Why future simulations could require an entire data center* Multi-agent simulations and what happens when simulated people interact* Replacing expensive human panels with synthetic populations* Why market research is only the starting point for simulation* Why Joon sees simulation as surprisingly similar to painting* Using simulation to study questions like UBI* Whether we are already living in a simulation* Why AGI and simulation may be the twin technologies of advanced civilizationsJoon Sung Park* LinkedIn: https://www.linkedin.com/in/joonspark* X: https://x.com/joon_s_pk* Website: https://www.joonsungpark.com* Simile: https://www.simile.comTimestamps00:00:00 Introduction and Joon's Path from Art to AI00:01:46 Smallville, Generative Agents, and the Origins of Simulation00:05:03 “Let's Just Create a World” and the Future of Personal Agents00:09:53 Social Physics and Behavioral Foundation Models00:14:08 Prediction vs. Simulation: How Do You Shape the Future?00:16:59 How Simile Models Real People and Populations00:25:35 Evaluating Simulations, Digital Twins, and 85% Accuracy00:30:23 Post-Training Models to Reproduce Human Behavior00:40:04 Scaling Laws and Simulating 8 Billion People00:43:10 From Schelling to Society-Scale Agent Simulations00:46:13 The Cost and Economics of Simulating the World00:52:05 Real-World Use Cases, Synthetic Populations, and the Market00:57:27 The Future of Simulation, Painting, and UBI01:04:23 Are We Already Living in a Simulation?01:06:08 Building Simile and HiringTranscriptIntroduction: Joon Sung Park, Simile, and the Story So FarVibhu [00:00:00]: Today, we have Joon in the podcast. Excited to kick this one off. Very exciting company. I wanna kick off and ask you the question, talk us through the story of your life. How have you gotten here?Joon [00:00:13]: Yeah, for sure. I'm really excited to be here. A story of my life. So I was born in Korea, and I lived there for a good 11 years or so of my life, and then my family moved to Boston. So we moved when I was 11, and my parents were doctors, so they were going through their postdoctoral studies. My dad was a surgeon, so he was doing his sabbatical years at the Boston Children's Hospital. So I grew up there, not too close to tech. I was very much a music and artsy, painting kind of guy.Vibhu [00:00:49]: Painting.Joon [00:00:49]: Exactly. I got into painting a little bit later, in high school, but that's what I used to do. And then I grew up mostly in the East Coast after Korea. So I lived a good number of years in New Hampshire, and then I went to college in Pennsylvania. And I got into more of this tech scene, in college. So I was originally trained to be an artist. I thought that would be my professional career. So it wasn't a hobby. It was like, “Hey, let's make a living out of this.” And then gradually, I got really interested in this idea of, hey, the greatest artist often creates their own medium, and the best medium that we had available today was in computation. So I decided to go deeper into that, and one thing led to another, and we can go deeper into this, but I decided that research was something that I gradually got interested in, and here I am.Smallville, Generative Agents, and the 2023 Breakout PaperSwyx [00:01:46]: So there's a lot that you packed into the research components. You had one of the best papers of 2023, which was the generative agents paper, commonly known as the Smallville paper.Swyx [00:01:58]: Feel free to call back to anything else that you mentioned, but most people would have heard of you from this. Do you have any statistics on how many people have, like, read it? arXiv gives you something, right? Some stats.Joon [00:02:10]: Yeah, it's a good question. How many people have read it, I'm not sure.Joon [00:02:14]: I know we do keep track of citations, and they are going up quite fast.Swyx [00:02:23]: Yeah, Google Scholar has 7,200 citations.Vibhu [00:02:25]: I feel like it made a bigger hit than that, and it was a pretty instrumental paper. It got cited so many times.Swyx [00:02:34]: It is frequently the answer when people ask, “What is the best paper you've read recently?” It's this one.Vibhu [00:02:39]: I thought the memory component was pretty underrated. It was a very good early memory system, and one of the biggest papers.Foundation Models and the Search for Killer ApplicationsJoon [00:02:47]: Yeah, so maybe I can talk a little bit about how this particular paper came together. So when I got into research, it was back in 2020 when I started my PhD program at Stanford, and that was the year, when we were about to get GPT-3 to be available. So we already had GPT-2, and you could sense that there was this new class of models that was just becoming available in the market, and the team got very intrigued. And the general consensus was, “Well, is this model going to be useful for anything?” “It's really strange that these models are not trained to do any particular task.” But we decided to take a bet. So a large group of scholars at Stanford, and it was led by one of my co-founders, Percy Liang, and we came togetherSwyx [00:03:35]: Who coined foundation models.Joon [00:03:36]: Who coined the term foundation models. We wrote this paper, where that term came from called Opportunities and Risks of Foundation Models. And during that process, really the thing that I started to think deeply about was, here is a model that is fundamentally new in our ecosystem. The reason why this was new was it wasn't, again, trained to do anything in particular, but its premise was it could do anything and everything. It was like a stem cell, if you were to take a biology analogy. And I got really interested in this idea that, well, if we were to really think about what are the killer applications that this particular technology would enable, what would that be? Many of my colleagues were using this for simple classification, simple generations. Interesting that these models can do that, but from an interaction perspective, not that interesting. We've known how to do that for many decades. And what we came down to was these models are trained on this very broad data from the web, right? So these are human behavioral data. It's social media, Wikipedia, all these data. So if you poke at the right angle, then you could see human behavior that would just pop out that's quite realistic, and we've never seen that before.The Time Machine Game and Recreating the WorldJoon [00:04:45]: So that got us really interested. The exercise that we decided to do, with this particular group of colleagues, Michael Bernstein, Percy Liang, and myself, who ended up becoming my co-founder at Simile, we sat down and we played this game that we call the time machine game.Joon [00:05:03]: Imagine we were to get on a time machine and fast-forward 10 years and look back. What would have been the single application that will have mattered that would be the most interesting and inspiring? And when we thought, “Well, what if we can just recreate the world that we live in?” it's really hard to get more ambitious than that. Like, let's just create a world.Joon [00:05:24]: And that's where we started. And initially, we had this paper that was a precursor to the generative agents paper called Social Simulacra.Swyx [00:05:32]: Before you go further, were there other candidates for the most ambitious thing in the time machine exercise? What was number two or number three?Personal Agents, User Models, and Why Simulation Came FirstJoon [00:05:44]: There is a close second that we were considering, which ended up becoming more of these automation tools, especially the vision around really personalized agents that would do things for you.Swyx [00:05:59]: That's also happening.Joon [00:06:00]: It's also happening. But it was interesting for us, right, in that the reason why, we decided to go with the idea of simulation, one, I was a huge science fiction nerd, and this idea of creating simulation, I was personally really just fascinated. I loved the idea. It's really cool to see, like, a game town like this and just see these agents live in it. But at the same time, my bet was if you were to create a really amazing personal assistant out of this technology, what you need first is an amazing model of your users. So I told a model, “Hey, can you go buy late dinner for me?” And it orders Hawaiian pizza, and I do not like pineapples on my pizza. Then it totally failed. The way for it to not make that mistake is only by having a deep understanding of who I am. And I gave a very simple and dumb example here, but you can imagine how this core understanding of people is instrumental. This is how, if we have our family and closest friends, they have a good mental model of who we are. That's the basis of our social connection. So our bet also was this technology around simulation, creating accurate representation of people ought to precede the more complex agents that would automate the world that we live in. So that was the bet. But that was a very close second, and I'm still very much fascinated by it. I think there's a lot of interesting work that's going around. My hot take here, though, is I don't think we've seen a true personal assistant that's useful, in ways that meet the ambition of that particular line of work. I think there are early applications that are interesting, and if you talk to even ChatGPT nowadays or Claude, they know a lot about us. So a lot of the generation it's doing, I do think it's much more tailored, but I think the ambition is quite large in that field, and I don't think we quite have all the right ingredients just yet.Swyx [00:08:01]: So OpenClaw and these personal agents, what do you want to see from them that they don't currently have?Memory, Markdown, and the Limits of PromptingJoon [00:08:09]: I do think it's slowly getting there, but I do generally want them to have much deeper understanding of the person. Right now, you look at the models. OpenClaw, what it's leveraging is a Markdown file, and I think it's quite clever, right? So if you look at the generative agents paper, this was the same intuition that we had, where initially when we were creating the memory architecture for the generative agents, and, like, this is, like, back in 2022, so we didn't really quite have the idea of even agentive architecture or the term agent. But the intuition that we shared with some of the work that's coming out today was we initially thought, “Well, do we want to make the memory into, let's say, knowledge graph? Do we want to train a bespoke model?” All of these things. And what we decided to do was, “No. Just forget about all this.” These language models are quite good at modeling text and understanding and reasoning about text. So just put everything in a Markdown file or a text file. You're done. I thought that was quite interesting that we could do that, and there's a lot of strength in doing that. But also, there are limitations. It's the way you retrieve and make sense of data that's extremely large, it takes a lot of work. So I think that technology is getting better. I also do, however, think, there are certain things you just cannot shape just by prompting the model. So to some degree, you do need to touch the parameters of the model itself. So there is this work that I do think does need to happen, and it is happening. The question is, how far can we take it? How do we source data, and how do you also create an ecosystem where people are continuously feeding data to this model so it's learning about you?Vibhu [00:09:50]: What's the intuition between why you need to do it in the model?Social Physics and Behavior Foundation ModelsJoon [00:09:53]: My intuition behind the actual when do you train or even post-train a model versus just prompt a model is if the model has to learn the underlying physics of the world that it's operating in. So it has to learn new social physics. The places where it doesn't have to train are the places where it already has the physics. We trust the physics. It already has the base statistics, but it's just trying to react to an environment. Then I think you can just prompt your way into getting the actions out of it. I don't think the models that are out in the open have yet learned the complete mapping of social physics of humanity. This is one of the core theses of Simile, right? And one of the core reasons why that is the case is if you look at the data that the model was trained on, these models were trained on the web data, like, whatever was available on the web. And these are really interesting data sets, but they are fundamentally the self-exposed attitudinal data with some behavior data that's sprinkled around here and there. And it has yet to learn the really deep behavioral nature of people, not just what people say they do online, but what they do in real life. And this is one of what I would consider to be the dark knowledge of humanity that we haven't quite captured. And it's these data that would also need to get factored into the model creation.Vibhu [00:11:21]: You call it behavior foundation model.Vibhu [00:11:23]: There's a good one-liner here, but outside of that, what type of data do you need? What are you changing on the model level? How do you go about modeling, doing a behavior foundation model?The Three Data Buckets: Interviews, Behavior, and CausalityJoon [00:11:35]: We think about data in three buckets. So one bucket is interview data. It's quite interesting. Rich qualitative data is interesting. It's not behavioral, but we would literally ask people, “Hey, tell me the story of your life.”Vibhu [00:11:53]: It's just what we're doing here exactly.Joon [00:11:54]: The question that you all asked at the beginning of this interview literally is the question we also ask. And we ask our participants to go a little bit deeper, than how far I went. Maybe I can give more of my life story in lieu of this. But the reason why that data is interesting is by learning about this very long-tail information about people, you get a lot of texture around this model, like, this person as a model. So even understanding their childhood memory or even their trauma, their first love, these things, quite informative in ways that's really hard to predict. So that's one. Then there are two tranches of what I would consider to be the behavioral data. One kind of behavioral data is observational. So these might be like transaction data, or these might be data that you can get by scraping the web, right? So you can imagine why these data sets would be interesting, right, because they give you the base statistics of people's behavior.Joon [00:12:55]: But then there is the last category of data, that I personally think is perhaps the most important, which is the data that describes the causal mechanism, the whys of people. Some of this is covered by the interview data, the qualitative, because people talk about why they made certain decisions. But really, where you get to see the most behavioral aspect of this is in randomized controlled trials, like RCTs. Imagine you have the same setup, but you have a few different variables that you are trying to tweak. Can you get realistic human behavior out of it in ways where, imagine you had this particular option. Imagine you're even trying to choose whether you're going to drink coffee or not. The day you drink coffee versus the day you didn't drink coffee, does your behavior change? That's a data set that describes a causal mechanism. This is quite important in modeling people. The reason why this is important is oftentimes when people come to us, or not just to us, but the reason why people are interested in simulation isn't because they want to predict the future. If you're trying to win against the stock market, predicting the future is interesting.Prediction vs. Simulation: Shaping the FutureJoon [00:14:08]: But most people, most decision-makers, what they want to know is, how can we shape the future? It doesn't really help you to hear that your sales are going to tank in two quarters. They're just gonna say, “Wow, that sucks.” What they want to know is, well, what do we need to do now to avoid that future? That's the causal mechanism. And this is also very hard data to come by, right, because the world is our ground truth, but it happens once. So in a very controlled setup where everything is equal except for one variable, this kind of data set rarely happens. So this is a reason why this data set is both hard to come by and quite important if you're trying to model human behavior.Swyx [00:14:50]: So behavior, I think, is the hardest data set to acquire. What is out there? What is even possible? You're not going to know a lot of details about my life. I don't even have data for myself on my own health or habits, and I just don't log everything. So how can you have that data?Joon [00:15:14]: So we run a lot of randomized controlled trials.Swyx [00:15:17]: But you put people in the lab, they watch them sleep, or what?Joon [00:15:20]: We do care a lot about the consent process. People know that we invite them to be a member of this community to both share data and have themselves represented in different forms. But we bring a lot of people to the lab, or virtual lab, where we design experiments that would pose them real behavioral decisions. And often in these experimental setups, what makes the difference between what is attitudinal versus behavioral is whether the stake in your decision is real. That's ultimately what makes it behavioral. So in these setups, we are inspired by our colleagues in social sciences, psychology, and so forth. So when they run studies, the techniques they utilize is imagine there's an online store that you're inviting people to come by. Then whatever they purchase in this experiment, they actually get that item delivered. Like, these are the things that make the stakes real. So we run a lot of these experiments, and we also do partner with firms. Right now, we also have customers who are quite excited to at least give us a glimpse of the behaviors that their users exhibit so that we can get a little bit deeper understanding of how people behave in these different platforms.How Customers Use Simile: Populations, Queries, and ExperimentsVibhu [00:16:39]: I think on the customer side, they have a lot of data about their users, who has bought. They have the action data.Vibhu [00:16:47]: Can you walk us through an example of what someone comes to you for? What questions would they want solved? Do you customize a model for them? Do you have something off the shelf? What does that look like?Joon [00:16:59]: Today, when people leverage our models, it's often to better understand the population of their interest. So usually, the start of the relationship, we come together and hear about what population they want us to model, right? So it might be that if you're a CPG company that's selling to all of the US, then maybe it's fairly straightforward. You want to model the gen pop of the US. But at the same time, if there is a vertical or if there's a market that they're trying to go into, imagine, they want to better understand, let's say, people in their 20s and 30s living in California. That's a much more specific population. So we hear about this population, and we go recruit these people, with consent, and with incentives, and we collect some of their data and create a model of these people. Then what our product allows you to do is query them. So it can take as input a filter that is a description of the population that you want to talk to, just like the one I just mentioned, and an environment. The environment can literally be survey questions, behavioral experiments, It can be A/B testing. Oftentimes, the core use cases are things like concept testing, to start with. But also, people sometimes want to do focus groups or one of the fun use cases that we also serve is even modeling things like earnings calls for public companies.Joon [00:18:21]: So these are the use cases that we often start with.Swyx [00:18:23]: Concept testing, is that an established term? I've never heard of concept testing.Concept Testing, Gallup, and PoliticsJoon [00:18:27]: Yeah. So it has to do with they have, let's say, different messaging, different products, different ideas.Swyx [00:18:32]: It's like a marketing exercise.Swyx [00:18:33]: Okay, got it. Got it. Politics?Joon [00:18:36]: We do, have a strategic partnership with Gallup, and of course, Gallup is deep into policy space and so forth. Right now, we have not worked deeply with politics, like that area just yet, however.Swyx [00:18:49]: I'm curious if there is demand or if they really would have different needs that somehow fundamentally don't mix with your existing, users or people.Joon [00:19:00]: I think there's certainly demand.Joon [00:19:02]: But we are very much mindful of how this technology gets adopted and the societal impact that we'll end up having with this technology. And I do see politics as an area where a company has to be particularly thoughtful about the way they operate and make impact. So this is where we also want to make sure that we form enough of guardrail and perspective on how to leverage this technology before we go on to serve markets like the politics.Swyx [00:19:29]: I'll give people an example. one of my favorite shows is The West Wing. I don't know if people have watched.Swyx [00:19:34]: One of the key storylines is, like, the president has, multiple sclerosis, but they haven't. they need to figure out how to disclose it. So they run a poll with a fake governor and ask people to respond on the poll,Counterfactuals, Polling, and When Simulation Is UsefulSwyx [00:19:47]: They try to make decisions based on the results of that poll on, like, how well they'll be received, like where, how should we play this?Swyx [00:19:54]: And I'm like, well, I think those counterfactual things, I would use a simulation for this if I could trust it.Joon [00:20:01]: For sure.Joon [00:20:02]: In that show, how'd it go?Swyx [00:20:04]: In that show, it was, like a foregone conclusion. They were like, “We know it's bad. We just don't know how bad.” And then the poll came back. It was like, “It's really bad.” And then they just did it anyway.Joon [00:20:14]: Part of it is to show, right? So you're, you're looking at the ideaSwyx [00:20:17]: Maximizing drama.Joon [00:20:18]: How bad could it be? Oh, it's horrible.Swyx [00:20:20]: And to some extent, I think that is part of the trick of the, or the challenge or with being a customer of yours, which is that if I know it's. if I roughly know and can intuitSwyx [00:20:35]: What the effect is going to be, do I need you? What sensitivity of it, of effect do I need in order to make a decision, right? So for example, if I, my approval rating is 50%Swyx [00:20:48]: And I, they have this negative piece, news item comes out, and it drops to 30.Swyx [00:20:52]: If it drops to 20, if it drops to 40, do I care? No. It, I know it drops. It's negative. So when do I care about simulations?Joon [00:21:01]: You do something that's clearly bad, that's not popular, and people don't like you, like, yeah, it's likeSwyx [00:21:05]: You don't need a simulation.Joon [00:21:07]: Yeah. Well, so there are a couple of things. one is, there are use cases where, like every day, developers, designers, policymakers, marketers, every single day, they create assets. They create new products. And turns out, it's many of the decisions in hindsight is obvious. Yes, of course this is bad, but we still run those studies because understanding the magnitude and understanding how acute something is quite difficult, even if, we feel like, of course, like this makes sense. this is the reason why we make so many mistakes. Like, every time somebody goes online and say something that has huge backlash, you look at that and like, “What an idiot.” However, it's tough. That's one. There's also another aspect here, which is, again, this is the reason why simulation is different from prediction. In simulation, in the ideal case scenario. So what simulation is trying to show is it's trying to show each step of the way or each step that we need to take to get to a certain outcome, right? So in the most advanced simulations, sometimes the next step that we're suggesting might be quite counterintuitive. The analogy that I sometimes give, and I ground it in a more realistic example, but, I, as I mentioned, I'm a huge fan of science fiction, and I don't know how, many of the audience members have read, like, things like the Foundation series by Asimov.Simulation as a Path, Not Just a PredictionSwyx [00:22:37]: Oh, yeah. We've mentioned psychohistory a number of times.Joon [00:22:39]: Okay, fantastic. So I might be, talking to the right crew. If you read Foundation series, literally the first act is there's a group of scientists who have found out that, “Oh, our galactic empire is going to collapse, and we're going to have 30,000 years of unrest.” And they run psychohistory, the simulator that tries to teach them, “Okay, how can we keep this unrest to a 1,000 years?” And they plan this out, and the first step of that plan is to get the scientists who say, “Okay, this is coming,” exiled into this random place in this, galax- galaxy.Swyx [00:23:18]: Terminus.Joon [00:23:19]: Exactly. And that's so counterintuitive. Like, what a strange move that you literally sent the group of scientists who was raising voice around this potential collapse of galactic empire into nowhere. How is that the right first move? Well, it turns out in this particular simulation, that was the move.Joon [00:23:40]: It's these things, right? And the reason why these reasoning is possible is because you're showing the step function or each step that results in a particular outcome. So really what simulation allows you to do in its highest form is you give it not a problem or question, like what would people answer to the survey? That's not what we do. What we tell it is, “Here is a goal that we have. In the context of foundation, we want to keep the unrest to a 1,000 years. What is the path that we need to take now to get to that particular future?” And that's what simulation allows you to do. Now, translating that into real market, imagine you're a automobile company and you're about to release a, EV, and you're trying to understand, well, how do we market EV, to make sure that our stock price goes up? But what if the answer comes down that, well, you can market your EV in XYZ way, but that might change people's perception around the cars that's not EV and make your overall sales to go down. Not very intuitive, especially all you're trying to optimize is EV salesss, and that's the only thing that you're tracking, then that might result in a completely wrong solution, or at least different solution than what you would have expected, whether it's right or wrong.Joon [00:24:57]: That's the power of simulation.Swyx [00:24:58]: For listeners, we covered a similar topic with Mikhail Parakhin from Shopify, where they are working on SimGym. I don't know if he ever talked to you about it. it's very similar.Joon [00:25:07]: ISwyx [00:25:07]: The goal is increased conversion, but then the journey is very unusual.Joon [00:25:12]: Journey is unusual.Swyx [00:25:12]: Yeah. The-- He's trying to look for interventions on a shopping trajectory, which is similar to what you're saying. Like, it's not about the attitudinal, is your word for it.Swyx [00:25:24]: It's about behavior.Joon [00:25:25]: It's about behavior.Swyx [00:25:25]: And that's exactly the difference, right? It's, like, not about the near-term direction about-- but it's more about, like, how do you affect multiple turns of interactions.Vibhu [00:25:35]: You had a good quote at the start about this as well. It's not about people wanting to know the outcome. It's about how they can change it, change the way to get there, something like that. But I wanna take it back to how do we know this is grounded? LikeGrounding and Evaluating Digital TwinsVibhu [00:25:47]: How do you run evals? How do you test that simulations come through? if I was to do the same thing that you described with, say, your favorite LLM, Opus, GPT-5.6, have some agent to map out these thingsVibhu [00:26:02]: How different are the answers we would get if I give it the same goal, the same objective, make a decent system? You're saying that you need to change the model weight. You have your own solution to this. But how far off are we, and how do you check if it's grounded? you have some interesting stuff on your site that points to how you run real evals, but if you could take us through that side. I think that's one of the big concerns that people have. They're like, “LLMs hallucinate.”Vibhu [00:26:27]: “You're just hallucinating layer after layer,” right?Joon [00:26:30]: The way we do this, and this is the paper that we worked on after the generative agents paper that really became the, at least for Simile and also the field of simulation and synthetic panels, really became the foundation. Yeah, this is the paper. the paper is called Generative Agent Simulations of 1000 People. Here's what we've done. For this paper, we brought 1,000 people that's representatively sampled from the US to a virtual lab. And what we have done was we spent two hours collecting fairly wide-ranging data. In this particular study, we focused a lot on this interview data, that was, whose script was taken from this project called American Voices Project. And then we would also pair that with a lot of behavior data and so forth, whatever we can collect within two hours. And then we would send these people away for a couple of weeks. And during that time, I would use this data to create their digital twins. And I would bring the humans, participants back after 2 weeks and have them complete a battery of surveys, experiments, behavior studies. So we have the list here, which included things like behavioral economics games. We would run literally, like, Big Five personality test, General Social Survey. We would also go ahead and run the randomized controlled trials that were published on PNAS. And we would have their digital twins predict how the source individuals would have acted in these studies and surveys. And this is where we could replicate people's behaviors and attitudes 85 percent as accurately as people would replicate their own. So that was the first really paper that gave this validated results that we can model individuals in an accurate way. And what we ended up finding now, of course, in AI space, so this paper came out at the end of 2024. AI space, a year and a half, 2 years, that's a lifetime.85% Accuracy and Why Frontier Models Miss Human BehaviorSwyx [00:28:24]: Yeah. Just, for listeners who are not seeing the YouTube, I just wanna say, like, the headline figure is 85 percent accuracy, like, which is a big improvement over all the otherSwyx [00:28:34]: Methods that you showed.Joon [00:28:36]: But the part that was particularly striking to us, especially as we improved this technology even further, was the generative AI models like ChatGPT, Claude that's coming out, it does give you the right foundation. However, what they do not consider is the true attitudinal and behavioral aspect of people, especially in the population that you care about. So what these models are really good at today is they're trying to become the super rational, objective machines, right? So you go get their data from places like Mercor, Scale. You talk to professional programmers, scientists to create model that's amazing at reasoning. That's what they do. Simile doesn't care about any of this. The models that we're talking about here, what we're trying to create are models that are as dumb as I am, right? So if I make some mistakes, the model has to make the same mistake.Swyx [00:29:34]: Oh, that's very hard.Joon [00:29:35]: That's very hard.Swyx [00:29:36]: You're solving Murphy's paradox.Joon [00:29:37]: That's exactly. And this is a completely different data and training objective. This is also where we see quite a bit of discrepancy in the performance in human behavior prediction between the frontier models, Simile's model, and the models being created in this space, where in some cases, the model performance of frontier models go all the way down to 20, 30 percent, especially if you go into that more niche population on topics that our customers would care about. On more gen pop, it might be around 50 to 60 percent. So it's not very robust. Like, you wouldn't want to make your decision off of these and these findings. If you can bring that up to 85 percent, that is ultimately what people end up getting very excited about.Swyx [00:30:20]: Yeah. Do we wanna keep going on the paper, routes?Joon [00:30:23]: Yeah, for sure. So the last one, was an interesting one. So this, paper was the follow-up paper that we had, to the 1000 agents paper, where the idea was now can we augment the models even further and post-train a model based on a lot of randomized controlled trials? So this was an interesting one. The data is always the most interesting part of modeling in many ways. The data that we got here was there's this, there's this platform called Open Science Framework. So some, the audience might be familiar with this. And there has been, especially in the social sciences over the past 5 years or so, there has been this concern around replicability of studies. And so it was a bit of a crisis, the scientists acknowledged, where we rerun the study and we don't see the same finding.Post-Training on RCTs and Replication StudiesVibhu [00:31:12]: Oof.Joon [00:31:12]: It's tough. And the reason why it's there-- that was often the case was there's this survival bias where the papers that get published often need to maintain what we call the value of less than 0.05 in the experiments that we ran. That suggests that only-- there's only 5% chance that the results that we saw is false positive. But the tricky part was all the papers that were not published, and there's still a 5% chance that whatever we publish is totally just randomly generated. Like, there's a 5% chance that, hey, this effect is not real, but it just happened to be real because of the sampling bias. So because of that, what scientists started to do was they started to register their studies. So before running an experiment, they would go to this platform and say, “Here is the data. Here is the population that we're collecting, and here's the hypotheses.” And they would just say, “Here is our hypothesis.” Like, “This is what we believe.” And you cannot retroactively change those hypotheses. This is what gives us more scientific statistical confidence that whatever effect that you ended up seeing is true. So that ended up creating this really interesting platform where there's one platform that has now contains tens of thousands of real-world experiments and hypotheses. And a lot of these are really high-quality, like, professionally designed behavior studies and random- randomized controlled trials. So we got the data and the studies from this platform and used that to make a point. And this particular, model is not, something that we're serving commercially because this was a part of the open science. But this particular data set, helped us make a point that by collecting a lot of these randomized controlled trials, that are really well-designed, we can make significant improvement in model's capability to predict human behaviors. So that's what this paper was about.Vibhu [00:33:10]: Is this stuff done on a individual level? Like, do I need to tune the model per individual, per company? Is there foundation model changes and then some slight post-training? Anything you can share there?Population-Level vs. Individual-Level ModelsJoon [00:33:21]: So this particular model was trained. the data we had at the level of individuals, but this particular model was trained. We experimented with both. And this is what we end up doing at Simile too. We always train 2, distinct model. One is what we call the population-level model. The other is what we call the individual-level model. And both take very similar input, which is the description of a subpopulation or individual and a stimuli. In this particular work, we've done the same. Here, the results that we are reporting are much more geared towards individuals because we do think that is a harder task in many ways, but that's what we have done.Vibhu [00:34:02]: You seen anything on the questions that humans can solve that models can't solve? So likeHuman Biases, Mundane Choices, and What Models MissVibhu [00:34:09]: Currently, it's, I live 5 minutes walk away from a car wash. It's a 10-minute drive. Should I walk or drive?Joon [00:34:16]: Huh.Vibhu [00:34:16]: The model will say, “Oh, walk to the car wash.” And, you don't have your car.Vibhu [00:34:20]: Is anything like this a problem in simulation? You would assume, like, very simple for human to think about, but if the model is saying you should walk to the car wash, anything here?Joon [00:34:32]: It's less, what can we solve, but I think it's more about what biases or mistakes do people make that models miss. Like, imagine that you are, like the. When I was still at Stanford, I lived in Palo Alto. So it's about, I would say, 40-minute walk from the campus. You ask the model, “Okay, let's go home. What can I, what can I do?” It would likely call an Uber or, give me, the bus time. But for the longest time, I really liked walking back. And the reason why I wanted to do that was not for efficiency. It really helped me think. And I like to walk for, half an hour or 40 minutes or so a day, where I just get to, just think about ideas, research, just get lost in my thoughts. That's very human activity. Unless the model has seen that and understands the importance of that activity, it would miss these kinds of features. So that I think, is fundamentally what we're trying to model. Like, what is fundamentally human might not be the most efficient thing to do, might not be the right thing to do, but things that make us who we are.Swyx [00:35:43]: I'm curious if, there are some data sets that you really want that would materially help you. One version of this may be interesting, which is more valuable to you to acquire as a data set, all of LinkedIn, all of Twitter, all of Facebook?What Data Matters: Social Media, Transactions, and FacebookJoon [00:35:57]: It's a little bit hard to rank, in part because, there's, there's this product saying where no feedback is wrong because it teaches you something about your users. Doesn't matter what feedback.Joon [00:36:11]: I think it's a little bit like that.Swyx [00:36:12]: So just whatever is bigger.Vibhu [00:36:13]: What about a different domain? Say it was. What about all of Amazon data?Joon [00:36:17]: Oh, yeah.Vibhu [00:36:18]: Shopping data, right?Joon [00:36:18]: Shopping data. So Amazon data is interesting in that it's very much behavioral, although, like, what people do on social media, you could squint and say that is also behavioral. But the transaction data is always interesting. It is also most commonly available, however.Joon [00:36:33]: If we were to look at purely social media, like if you really, if I were, if I had to really pick, Facebook likely is interesting because I do think it is most a default version of people. Because you go to LinkedIn, it's very much professional environment. So people put up their, they have their guards up, right? And that still is interesting because that is true human attitude and behavior, but it is not your base state. you go to Twitter- Twitter, people have their own crazy personas, or depending on who you are. Like, my Twitter profile and, persona is very much, initially was I was very much an academic. “Hey, I'm here to share my studies.” Now, I share, things that's related to Simile. But Facebook is one of those more private space where people just connect with their friends. In that way, I do think it shows you a little bit more about who that person is. So if I had to pick, I'd likely pick, Facebook.Swyx [00:37:30]: Yeah. And you're interested in, like, the whole person and their background and philosophy. I, is it too clinical or too machine learning-oriented to just say this is just ways to inject variance and biases? The broad question, is, like, is this any better than a randomized, like, combinatorial explosion version? So we have a link to the TencentBillion Personas, Synthetic Demographics, and Bespoke DataSwyx [00:37:54]: Billion persona paper, where they did not do any of the groundwork that you are doing.Swyx [00:37:59]: They just did like a cross matrix of here's all the professions in the world, here's all the people, possible backgrounds in the world, do a dot product across all of them, and that's it. That's your prompt for a billion people.Swyx [00:38:12]: This will do something. I don't know if it'll do what you do, but it gets you some way, some percent of the way there.Joon [00:38:18]: So this was an interesting paper. Like, what I admired about this paper when it came out was the scale. And you do gradually want to be able to simulate really large societies and interactions. So the scale is definitely admirable. it is relying heavily on the known statistics that went into training the model. So to the extent that you believe that statistics is correct, this is not a bad way to go about this. But the thesis here, and this is something that we also have seen in the market, like if this works, then we have solved simulation.Joon [00:38:54]: It,Swyx [00:38:55]: Because I survey, like, okay, 5% of the US population is in construction.Swyx [00:39:01]: The other 5% is in medicine, whatever, right? And then you just keep going down the list, and then you do the other side. 5% has, like, the big 5 personalitySwyx [00:39:08]: Of, like, neurotic or whatever. That's it.Joon [00:39:11]: That's it. So if you believe that the underlying data set and the platform that we're leveraging has all the right statistics, then this will have solved it. you're at that point merely retrieving the knowledge that is already embedded in the model, in the model parameters. That's not, unfortunately, what we see, where there is such detailed and also niche knowledge about people that if you just take one example, it might feel very mundane, but it's quite rich when you put together, that you do need to do a lot of bespoke data collection to better understand people. And this is also, I think what makes this particular, job fun, which you want to deeply understand people, and the process of deeply understanding them requires a lot of attention to the details. And you do need to pay attention to and pay respect to the daily lives that people lead.Scaling Simulation: From Thousands to SocietiesVibhu [00:40:04]: I wanna talk about scaling simulation.Vibhu [00:40:07]: So what can't we simulate, what can we simulate, and how does scaling affect this? So how big are the models? What if we go from, 8B, like, couple 100 billionVibhu [00:40:18]: Like billion000 parameters, billion000? Do we get scaling? Any interesting emergence? Like, at a certain scale, at a certain amount of training, you uncover anything unusual and any learnings from that?Joon [00:40:31]: What we are seeing is at Simile, so we do post-train our own model. The thing that we're seeing is the early glimpse of scaling law in simulations. The more data about humans and more compute you ingest, you start to get predictive and predictable gains of the model performance in simulating it, simulating people.Vibhu [00:40:51]: Ooh. We need a scaling law curve.Joon [00:40:52]: It's scaling law. Whenever you find it's a beautiful thing. And we're starting to see the glimpse of it, which is quite exciting. But if you talk about the ambition of simulation as a whole, it's not merely about building a model. It's about building a model, then creating the agents that become the individuals in a much larger ecosystem. So they're creating this multi-agent simulation. Down the line, you want these multi-agent simulation to also live in a very rich environment, right? What we are really trying to get to at that point is, hey, can we create. All right, let's do a time machine game again, and 5 years, 10 years into the future, can we create a simulation of 8 billion people living on Earth? I think that's quite interesting. And that really is the vision. And once you get to that state, the questions that you can help answer for the society also start to change from my perspective. The answers are fundamentally about emergence of the emergent behavior of society and large groups of people.Joon [00:41:53]: So the questions that I get excited by, and maybe this is a stodgy- a bit. I have my, academic side of me.Joon [00:42:01]: And for me, it's questions like, can we help solve climate change? If you look at climate change as a problem space, this is what we, like social scientists would often call it the wicked problems, problem where you have many actors with competing incentives for trying to make a very complex decision and coordinating that coordination decision. Very difficult to really solve in real life, which is also the reason why we couldn't solve it. Can simulation help us solve that? Another one is, can we understand the signals for collapsing democracy, or can we understand or can we uncover the origin story of the monetary system? These are societal questions that we never really had a good way of answering. If we can create simulations of our society, you have to believe that these are the problems that we can solve. So that's really the ambition of this field. And, I also think, yes, I think there's a Nobel Prize to be won there, which wouldn't be surprising. And I think there's some amazing societal impact that we can have to help people make better decisions.Climate Change, Democracy, and Societal SimulationSwyx [00:43:04]: Nobel Prize in economics?Joon [00:43:06]: In economics.Swyx [00:43:06]: Oh, I see. I see. Rooting for you to write that paper.Joon [00:43:10]: One of these days. But, one of the scholars that I was deeply inspired by, When I was coming into the space of simulation, is this scholar, named Thomas Schelling.Schelling, Agent-Based Models, and the Nobel PrizeSwyx [00:43:23]: Schelling point?Joon [00:43:24]: So the canonical example of the work that he's done was he was one of the creators of agent-based modeling. So this was, like, in the 1970s and 80s. It's very early days, but this was truly one of the first exemplars of simulations. And one of the canonical model from that time, and of course many of these simulations are trying to tackle the societal problems that's most relevant for their era, it was called the model of segregation. So racial segregation was a big topic, that, we cared about. And what they've done was they created this grid world where they had red dots and blue dots. And these dots were, back in the day, like, they were the agents, and they had a simple rule that governed their behavior. If certain percentage of your neighbors are of different color and if that goes above certain threshold, then you move to a new location at random.Joon [00:44:21]: One of the striking finding of this paper or this agent-based model was for the longest time, people thought the segregation within society was caused by explicit and overt racism.Joon [00:44:34]: But if you look at this model, people's preference towards living with people of the same color, that preference can be very minute.Joon [00:44:42]: But the very small difference causes the society to segregate completely over time. This was very counterintuitive for a lot of people. And this particular work ended up informing housing policies. Mixed income housing, got really inspired by this work. And Thomas Schelling ends up winning the Nobel Prize for having laid the groundwork for very early versions of simulations. The opportunity that I do see here in the more scientific terms, is agent-based models for the longest, had impact in the 1980s, 90s, to some extent, early 2000s, but it has now gotten forgotten by the community a little bit. Because as you can imagine, red dots and blue dots is not really a rich description of people.Joon [00:45:31]: But with the emergence of things like generative AI and, in particular, generative agents, we do have an opportunity to create these agent-based models that are high fidelity enough to help us make really complex decisions. And that's the opportunity that I see. If that truly works, then yes, that is the work that will result in a Nobel Prize.Swyx [00:45:53]: Yeah. For what it's worth, and I grew up in Singapore. 80% of Singapore is in public housing, and public housing has, enforced racial quotas for exactly that reason, which is very interesting. okay, so we talk about scaling, we talk about all these, the agent possible applications.Cost, Reuse, and the Economics of SimulationSwyx [00:46:13]: I'm scared about the cost. if you even-- let's just keep it to the US, about 8 billion people.Swyx [00:46:21]: But, how much does it cost to model so many hundreds of millions of people?Joon [00:46:26]: Oftentimes today, we don't start at that scale, this stage of the, of industry and simulation as technology. But we can get our users extremely rich and meaningful insights even by modeling thousands, tens of thousands of people. And today what we do is every week we are collecting data on the scale of tens of thousands people's data, and we have panel partnerships that gets us to tens of millions of people globally. So that's what we do today.Swyx [00:46:55]: And just as a side note once you've collected one person for one studySwyx [00:46:59]: Can you reuse that same person for all the subsequent studies?Joon [00:47:03]: That's exactly right.Swyx [00:47:03]: Okay.Joon [00:47:04]: The beauty of this model and these agents is the fact that they are domain-agnostic.Joon [00:47:08]: That what you're really trying to understand is what is the fundamental nature of these people? What's their social physics? And there are a lot of, a lot of, people that does change over time. Like, even, like, even things like, how many times have you gone have you been to, like, CVS the past week? that will change. But there's so many traits about people that are also known to never change. Like, your risk tolerance doesn't really change over time. It's very consistent. So it's these things that we're trying to learn. But the scale we are operating is right now hundreds or, tens of thousands to hundreds of thousands. And in many of the core use cases that we are deployed in, and this is more than enough population, to cover those. Really, at that point, what you care about is less the number of people, but more do you have the right subpopulation of interest covered? And this is also the reason why people want a larger sample. It's not because they want, stronger statistical guarantees. It's more that can they filter down to any population of their interest. However, you can also imagine in 10 years, if we truly believe that the compute is going to scale, that we'll have much more availability for compute, and our ambition for simulation is also going to scale accordingly, there's definitely a reason for us to create an entire data center worth of simulations.Joon [00:48:35]: Or in my hunch here is I do think in the next some number of years, we will start creating simulations that will cost as much as training a foundation model. But perhaps it's going to be so valuable to the society that it would be a no-brainer. Right now, even today, like, we are training bunch of new foundation model just so we can say we trained one and we spent tens of millions. But if we can create a simulation at the level of society that would solve climate change, I would run that today. I would raise the money right now just to run that.Multi-Agent Simulation and Social InfluenceSwyx [00:49:10]: Amazing. the follow-up question is, does it also compound if you let the simulations talk to each other?Swyx [00:49:18]: Or do they already do that today? They don't, right, as far as I understand?Joon [00:49:22]: It depends on what simulation you're trying to run.Joon [00:49:24]: In the multi-agent simulation setup, the agents do talk to each other.Swyx [00:49:28]: Right, which is exactly Smallville, right?Joon [00:49:29]: That's right.Swyx [00:49:30]: But a lot of times, for example, in commerce, you're just by yourself, so there's no point talking. which is way cheaper.Vibhu [00:49:37]: But they use all these levels, right? Like, you decide what you will buy based on what other people around you buy and talk about, right?Swyx [00:49:43]: It depends.Vibhu [00:49:44]: It depends.Swyx [00:49:45]: Again, I'm, I'm coming at this from a cost point of view. I'm like, “Oh my God.” LikeVibhu [00:49:48]: I thinkSwyx [00:49:49]: If there is, like, some combinatorial thing of, like, thousands of people talking to thousands of people, then that one million X's might cost.Vibhu [00:49:56]: I have a very different view as the cost point aside. Like, running these studies in reality is a lot more expensive, right? Running any study like this is you gotta have people do it, you gotta sign people up. It's very expensive and sometimes, like, not feasible to run the study.Vibhu [00:50:14]: But the outcome or the decisions you make are very expensive on them, right? So spend X million on something that, the overall process costs 100 million might as well, right? There's, there's a lot of value to be had there. It's a small cost, but I'm excited on the cost side.Joon [00:50:33]: To some extent, and when you deploy technology, you often want to deploy in a way where you can replace existing budget or you can make things more efficient, and that is the best way to deploy. However, the way you capture the long-term value of the technology is making the argument that, no, it's the upside, that by making this better decision using simulation, you have saved yourself or made yourself hundreds of millions or even billions of dollars, and that's a case to be made.Vibhu [00:51:06]: Random tangent question. So if you're doing a lot of inference, a lot of model multi-agent stuff, are you at the point where it makes sense to, train a model that' very sparse? You're expecting to do multi-million dollar runs. Are you thinking about this in model architecture standpoint or inference efficiency, or, you're still at the research phase of it works, we're not super there yet?Joon [00:51:34]: Efficiency, we do think quite a bit about. this is technology that is deployed now in some of the largest enterprise companies in the world, and we do process significant number of queries, that are trying to, simulate the populations in the world. So efficiency is a consistent thing. we don't want to over-optimize too early, so I wouldn't say, like, this is the higher bid Right now, but this is definitely something that we think pretty carefully about.Swyx [00:52:05]: Yeah. Are there other case studies? So we, you talked about CVS, talked about Gallup, Deloitte, Wealthfront.Efficiency, Enterprise Use, and Real-World Case StudiesJoon [00:52:12]: Wealthfront is an interesting one, because one of the things they were trying to do, they were one of the first customers that wanted to do product testing that goes beyond just asking people what they think about, let's say, behavior experiments and so forth. So there, really what we had to do was reason about multimodal input, so images, but also you can also imagine, like, these agents traversing through Figma mockups or websites. So some of the things that our agents can also do is it can be given a domain, like, or, like, a website URL and go use it for a while. It's these things. And Wealthfront was one of the first, customers, that was very excited about this possibility.Vibhu [00:52:53]: What have people been asking? Like, is there any demand that we have not covered? Like, UI testing, right?Vibhu [00:52:59]: I wanna try a new. I wanna ship a new feature, test the UI, simulate how people will do it. Any interesting things that you're seeing demand for?Product Testing, Websites, and Synthetic PanelsJoon [00:53:08]: Today, a lot of the demand does come from like, the places where people have historically used human panels, we can now replace with agents, and these synthetic populations. And this is not replacing human panel. in many ways, the simulation that Simile is building is grounded. So the way that I think about this is we are trying to represent humanity at scale. And in that way, the use cases are what we would expect, but it's the scale of deployment that surprises me.Joon [00:53:44]: Turns out there are so many decisions that people make every day in these organizations, groups, and we want to be able to say, “We listen to people. We have consulted our users.” But in reality, that is rarely the case because getting to people and asking them many questions, it's difficult. It's both costly, time-consuming, but most importantly, people are just not available. If I had to answer 1000 survey questions for this one particular, vendor, even if I wanted to do that, like, I would never do it. And that's very much the case. What simulation can do is ensure that the voices of people are always represented in rooms where the decisions for them is made, right? So all the stakeholders of this particular product launch, ideally they're consulted. That's what this technology really is trying to enable.Market Size, TAM, and Human Decision-MakingSwyx [00:54:39]: In my mind, that means it skews towards more consumer focus, right? Like, anything with a wide enough customer base where you do benefit from the diversity that you represent. What are some rough statistics, just for people who are not familiar with this market in general, what's the market size that. I'm sure you have some, like, rough numbers. market size is, like, a vague questionSwyx [00:55:01]: But, like, how much do people spend?Joon [00:55:03]: So market research is a $100 billion industry.Joon [00:55:06]: But the thing about simulation is not a tool for market research. Simulation is a tool for human decision-making. So the question around what is a TAM here is quite tricky, right? Because it's easy to say, “Well, market research TAM is roughly 100 million or 100 billion.” so is it a TAM? And not really, right? Because in many ways, you're trying to inform all human decision-making. You're trying to inform every decision that are made about humans for humans. What is a TAM for that? It's really unclear. And I'll be honest. Like, I have a scientific background, I have a research background, so I didn't come into the field calculating, oh, what is the TAM for human decision-making? But I just had to assume, well, if we can inform every decision that is made about human for human, that has to be big.Swyx [00:55:58]: Some- something valuable.Joon [00:55:59]: Exactly.Swyx [00:55:59]: To some extent, you are a unicorn founder now, and you have to care as a CEO. But, like, I do think, like, yeah, when you go into these boardrooms with people that you're quoting millions of dollars of contracts for, like, you have to say, “Well, here's what you spend on humans-”Swyx [00:56:15]: “. And here's what we save you, and it's 85% similar.”Joon [00:56:19]: And certainly, the value case, is something that we care deeply about. Like, what is the value that we provide to the users and the decision-makers? But this is also where, like, as a founder, I think valuation only tells one very superficial aspect of the story, and I try not to think too much about valuation, in general, because that's not what also motivates a team or certainly doesn't. I'm, I-- Again, the interesting thing about researchers is we are happy living in academia, getting paid next to. we get paid okay. we don't get paid that much, as a researcher here in academia, but it's the impact and it's the, it's the value that we can provide to the individuals and the society that really drives us. And in that way, ultimately what drives us is the impact. Does the simulation we provide have a real impact in people's decision-making in ways that progresses our society forward? If the answer is yes, then yes. that has to be great business, and we see that in numbers, and we do care deeply about that upside story, but that's the heart of it.Where Simulation Goes NextVibhu [00:57:27]: Do you have any timeline predictions? So we talked about scaling laws of simulations.Vibhu [00:57:33]: You brought up, okay, maybe one day we can simulate how to solve climate change.Vibhu [00:57:38]: Where are we now?Vibhu [00:57:40]: If that's not the end state, what is an end state, and what does progress look like?Joon [00:57:45]: So what I sometimes tell people is simulation as industry, it feels a lot like where GPT-3.5, GPT-4 was, for the AGI saga, which is we have now technology that is powerful enough to do real damage on the verticals that we are tackling. At the same time, there's a lot of progress that is yet to come. And that's, I think, where this is. So the way I see it, I do think there will continue to be breakthroughs both in data, in algorithms, and there will be much more aggressive scaling that will also happen over the next few years. But I think that's roughly where we are.Swyx [00:58:27]: I think that was about the ro

This week we speak with Dr. Ted O'Leary, Co-Director of Adult Congenital Heart Disease Electrophysiology at Boston Children's Hospital about a recent publication he authored on the use of pulsed field ablation (PFA) for the transcatheter ablation management of complex atrial arrhythmias in ACHD patients. How does PFA work and what are some of the potential advantages and disadvantages of this novel ablation energy technology? What are the advantages of a variable loop catheter in this setting? Is PFA going to supplant radiofrequency current for standard "SVT" ablations one day? These are amongst the questions reviewed with Dr. O'Leary this week. DOI: 10.1161/CIRCEP.125.014619

Deena Nathan's five year old son Hayden is autistic and non-speaking, and he's fluent on his AAC device. In this episode she walks through a day that starts with therapy at 8am, the win she's still not over, and the one thing she wants people to understand about a kid who doesn't talk. She's also honest about something most people won't say out loud. She has real support, good family, friends who get it, and it's still lonely. Both of those things are true at once, and that might be the most useful thing in this conversation. What you'll hear 00:00 Welcome 00:43 Meet Deena, Hayden, and the family 01:43 A day built around therapy, and being the chauffeur 04:42 The hardest part is time, and the guilt that comes with it 06:16 The win, the day he called out for Mom 08:02 Who Hayden is, hyperlexic, happy, and fluent on his AAC device 10:28 What she wishes people outside the community understood 12:00 Supported and still lonely 13:22 What she wishes autism families understood, no one's future is predicted 14:57 Feeling seen and heard inside the community 15:58 Why families at different levels end up disconnected 17:48 Deena's coaching work with special needs parents 18:21 Why Rob started sharing in the first place 21:33 Closing About the guest Deena Fierstein Nathan is a Certified Life Coach at DFN Connected Growth Coaching, where she works with parents of kids with unique needs. She lives in the North Shore suburbs of Chicago with her husband Kevin and their two kids. She stopped working when Hayden was diagnosed and went all in, including taking classes with his AAC device company so she could use it with him. Website: dfnconnectedgrowth.com Instagram: @connectedgrowthwithdeena Sponsors This episode is sponsored. Mightier is a biofeedback emotional regulation program for kids developed at Boston Children's Hospital. Use code theautismdad22 for 10% off at theautismdad.com/mightier-review. Best Part Kids is a sensory-friendly multivitamin for selective eaters created by dietitian Brittyn Coleman. Use code THEAUTISMDAD for 10% off at BestPartKids.com. About your host Rob Gorski is the founder of The Autism Dad. His book, So Your Child Was Just Diagnosed with Autism, is out December 29 2026. theautismdad.com/book

This video discusses the preoperative, operative, and postoperative considerations for patients undergoing tracheostomy including: anatomy and pathophysiology, anesthetic and operative approach, and postoperative care. LEARNING OBJECTIVES - Explain the anatomy and pathophysiology - Describe the anesthetic management plan, including intraoperative management - Review common operative approaches - Describe postoperative considerations AUTHORS Roger Nuss, MD Associate, Department of Otolaryngology and Communication Enhancement Assistant Professor of Otolaryngology, Harvard Medical School Jennifer Perez, MD Fellow, Division of Critical Care Medicine Boston Children's Hospital Jessica Laird-Gion, MD Department of Pediatrics, Division of Cardiology Stanford Medicine DATE Initial publication date: August 12, 2026. Please visit: www.openpediatrics.org OPENPediatrics™ is an interactive digital learning platform for healthcare clinicians sponsored by Boston Children's Hospital and in collaboration with the World Federation of Pediatric Intensive and Critical Care Societies. It is designed to promote the exchange of knowledge between healthcare providers around the world caring for critically ill children in all resource settings. The content includes internationally recognized experts teaching the full range of topics on the care of critically ill children. All content is peer-reviewed and open-access thus at no expense to the user. For further information on how to enroll, please email: openpediatrics@childrens.harvard.edu CITATION Laird-Gion J, Perez J, Nuss R, McFee AM, Marcley S, Wolbrink TA. Tracheostomy. 08/2026. Online Podcast. OPENPediatrics. https://soundcloud.com/openpediatrics/tracheostomy-by-r-nuss-j-perez/s-hIyYqiXKAId?si=25e19540480b43cbb133b57d067213f9&utm_source=clipboard&utm_medium=text&utm_campaign=social_sharing.

In this Complex Care Journal Club podcast episode, Ms. Emily Johnson and Dr. Florence Gagné discuss a scoping review of interventions to assess social needs for children with medical complexity. They describe the different approaches to screening and intervention in the five included studies, implications for practice, and opportunities to engage social workers in research. SPEAKERS Emily Johnson, MSW, LICSW Clinical Social Worker Boston Children's Hospital Florence Gagné, MD Pediatrician Montréal Children's Hospital HOST Kristina Malik, MD Assistant Professor of Pediatrics Medical Director Pediatrician, Special Care Clinic‌‌ ‌University of Colorado School of Medicine KidStreet Children's Hospital Colorado DATE Initial publication date: August 11, 2026. JOURNAL CLUB ARTICLE Johnson ER, Hadge SM, Wachter SM, Gagné F. Interventions to assess social needs for children with medical complexity and their families: A scoping review. Patient Educ Couns. 2026;148:109555. doi:10.1016/j.pec.2026.109555. OTHER ARTICLES REFERENCED Ming DY, Jones KA, Sainz E, Tkach H, Stewart A, Cram A, Morreale MC, Dizon S, deJong NA. Feasibility of implementing systematic social needs assessment for children with medical complexity. Implement Sci Commun. 2021 Nov 21;2(1):130. doi: 10.1186/s43058-021-00237-3. PMID: 34802465; PMCID: PMC8606226. TRANSCRIPT https://cdn.bfldr.com/D6LGWP8S/as/3sgvpf2qjsvt9zqxvf37xspz/Gagne_and_Johnson_Final_Transcript_8-3-26 Clinicians across healthcare professions, advocates, researchers, and patients/families are all encouraged to engage and provide feedback! You can recommend an article for discussion using this form: https://forms.gle/Bdxb86Sw5qq1uFhW6. Please visit: http://www.openpediatrics.org OPENPediatrics™ is an interactive digital learning platform for healthcare clinicians sponsored by Boston Children's Hospital and in collaboration with the World Federation of Pediatric Intensive and Critical Care Societies. It is designed to promote the exchange of knowledge between healthcare providers around the world caring for critically ill children in all resource settings. The content includes internationally recognized experts teaching the full range of topics on the care of critically ill children. All content is peer-reviewed and open-access thus at no expense to the user. For further information on how to enroll, please email: openpediatrics@childrens.harvard.edu CITATION Johnson ER, Gagné F, Malik K. Screen and Intervene: Meeting Social Needs for Children with Medical Complexity. 08/2026. OPENPediatrics. Online Podcast. https://soundcloud.com/openpediatrics/screen-and-intervene-meeting-social-needs-for-children-with-medical-complexity.

While prosecutors in the Lindsay Clancy murder trial argue she faked her injuries, a Duxbury police officer confirmed on the stand that a Code Blue was called for her hospital room at Brigham and Women's. The officer spent sixteen hours watching Clancy lie sedated and motionless. She never said a word.Day 4 of testimony at Plymouth Superior Court started with the jury touring the Duxbury house at 47 Summer Street. They went through in groups of six — the basement where Patrick Clancy found the children, the upstairs bedroom where blood was found on the floor, the bed, the walls, and the windowsill, and the second-story window prosecutors say Lindsay jumped from. The judge overruled the current homeowner's objection to the visit.A detective testified about meeting Clancy at South Shore Hospital, where she was unconscious with lacerations across her neck and wrists. Defense attorney Kevin Reddington showed photographs of blood throughout the bedroom and a knife on the nightstand. Then ER physicians described treating Dawson Clancy, three years old, for forty minutes before declaring him dead — and getting eight-month-old Callan's heart beating again only to find no brain activity. Callan died at Boston Children's Hospital.Clancy is charged with three counts of first-degree murder. Her defense argues postpartum psychosis made her unable to appreciate the wrongfulness of her actions. The trial continues Monday.Join Our SubStack For AD-FREE ADVANCE EPISODES & EXTRAS!: https://hiddenkillers.substack.com/ Want to comment and watch this podcast as a video? Check out our YouTube Channel. https://www.youtube.com/channel/UC8-vxmbhTxxG10sO1izODJg?sub_confirmation=1 Instagram https://www.instagram.com/hiddenkillerspod/ Facebook https://www.facebook.com/hiddenkillerspod/ Tik-Tok https://www.tiktok.com/@hiddenkillerspod X Twitter https://x.com/TrueCrimePodDisclaimer: This publication contains commentary and opinion based on publicly available information. All individuals are presumed innocent until proven guilty in a court of law. Nothing published here should be taken as a statement of fact, health or legal advice.#LindsayClancy #LindsayClancyTrial #HiddenKillers #PlymouthSuperiorCourt #CodeBlue #PostpartumPsychosis #TrueCrime #DuxburyMA #MurderTrial #JuryTrial

Officer Richard Lippard of the Duxbury Police Department testified that he spent sixteen hours in a hospital hallway watching Lindsay Clancy lie motionless. She was sedated and unconscious at South Shore Hospital, then MedFlighted to Brigham and Women's in Boston. She never spoke a word during his entire watch. Under cross-examination, Lippard confirmed that a Code Blue was called for her room overnight — meaning she was dead or dying.The testimony came on Day 4 of Clancy's murder trial after the jury walked through the family's former home at 47 Summer Street in Duxbury. Jurors inspected the basement, both floors, and the exterior — including the second-story window and the yard below it. A detective who met Clancy at the hospital described her as sedated and unconscious with deep lacerations across her neck and wrists. Photographs of the injuries and blood in the bedroom were shown to the jury.Two emergency room doctors then testified about treating three-year-old Dawson and eight-month-old Callan. Dawson was worked on for forty minutes before being declared dead. Callan's heart was restarted but he never regained brain function and died at Boston Children's Hospital days later. Clancy was visibly emotional as both doctors described the effort.Every witness Friday was a prosecution witness. And the prosecution's own officer confirmed their defendant was dead or dying the same night they allege she was performing.Join Our SubStack For AD-FREE ADVANCE EPISODES & EXTRAS!: https://hiddenkillers.substack.com/ Want to comment and watch this podcast as a video? Check out our YouTube Channel. https://www.youtube.com/channel/UC8-vxmbhTxxG10sO1izODJg?sub_confirmation=1 Instagram https://www.instagram.com/hiddenkillerspod/ Facebook https://www.facebook.com/hiddenkillerspod/ Tik-Tok https://www.tiktok.com/@hiddenkillerspod X Twitter https://x.com/TrueCrimePodDisclaimer: This publication contains commentary and opinion based on publicly available information. All individuals are presumed innocent until proven guilty in a court of law. Nothing published here should be taken as a statement of fact, health or legal advice.#LindsayClancy #LindsayClancyTrial #HiddenKillers #PlymouthSuperiorCourt #CodeBlue #PostpartumPsychosis #TrueCrime #DuxburyMA #MurderTrial #JuryTrial

While prosecutors in the Lindsay Clancy murder trial argue she faked her injuries, a Duxbury police officer confirmed on the stand that a Code Blue was called for her hospital room at Brigham and Women's. The officer spent sixteen hours watching Clancy lie sedated and motionless. She never said a word.Day 4 of testimony at Plymouth Superior Court started with the jury touring the Duxbury house at 47 Summer Street. They went through in groups of six — the basement where Patrick Clancy found the children, the upstairs bedroom where blood was found on the floor, the bed, the walls, and the windowsill, and the second-story window prosecutors say Lindsay jumped from. The judge overruled the current homeowner's objection to the visit.A detective testified about meeting Clancy at South Shore Hospital, where she was unconscious with lacerations across her neck and wrists. Defense attorney Kevin Reddington showed photographs of blood throughout the bedroom and a knife on the nightstand. Then ER physicians described treating Dawson Clancy, three years old, for forty minutes before declaring him dead — and getting eight-month-old Callan's heart beating again only to find no brain activity. Callan died at Boston Children's Hospital.Clancy is charged with three counts of first-degree murder. Her defense argues postpartum psychosis made her unable to appreciate the wrongfulness of her actions. The trial continues Monday.Join Our SubStack For AD-FREE ADVANCE EPISODES & EXTRAS!: https://hiddenkillers.substack.com/ Want to comment and watch this podcast as a video? Check out our YouTube Channel. https://www.youtube.com/channel/UC8-vxmbhTxxG10sO1izODJg?sub_confirmation=1 Instagram https://www.instagram.com/hiddenkillerspod/ Facebook https://www.facebook.com/hiddenkillerspod/ Tik-Tok https://www.tiktok.com/@hiddenkillerspod X Twitter https://x.com/TrueCrimePodDisclaimer: This publication contains commentary and opinion based on publicly available information. All individuals are presumed innocent until proven guilty in a court of law. Nothing published here should be taken as a statement of fact, health or legal advice.#LindsayClancy #LindsayClancyTrial #HiddenKillers #PlymouthSuperiorCourt #CodeBlue #PostpartumPsychosis #TrueCrime #DuxburyMA #MurderTrial #JuryTrial

The doctors who treated Lindsay Clancy's three children took the stand today in her murder trial. Clancy, 34, of Duxbury, Massachusetts, is accused of strangling 5-year-old Cora, 3-year-old Dawson, and 7-month-old Callan with exercise resistance bands inside the family's Summer Street home on January 24, 2023. She faces three counts of murder and three counts of strangulation, has pleaded not guilty, and is mounting an insanity defense — attorney Kevin Reddington argues she was in the grip of severe postpartum psychosis and psychiatric overmedication when it happened.Dr. Michael Snyder of Beth Israel Hospital, Dr. Andrew Capraro from the Boston Children's Hospital ER, and Dr. David Casavant from the Boston Children's ICU testified about how the children arrived and what treatment looked like once they got there. Central to their testimony: the brain injuries caused by lack of oxygen, injuries that hit hardest in Callan, the youngest and most vulnerable of the three. When doctors describe irreversible brain damage in a baby who hadn't even started crawling, there's no legal maneuvering that softens it. That's the part of this trial no defense strategy gets to touch.Prosecutors are expected to argue Clancy understood the nature of her actions despite the defense's mental-health claims. After the killings, Clancy allegedly attempted to take her own life by jumping from a second-story window, leaving her paralyzed from the waist down. Her husband, Patrick Clancy, was out of the home running errands at the time and has since relocated to Manhattan. The trial, underway in Plymouth Superior Court before Judge William F. Sullivan, is expected to last several weeks.LinksJoin Our SubStack For AD-FREE ADVANCE EPISODES & EXTRAS!: https://hiddenkillers.substack.com/Want to comment and watch this podcast as a video? Check out our YouTube Channel. https://www.youtube.com/channel/UC8-vxmbhTxxG10sO1izODJg?sub_confirmation=1Instagram https://www.instagram.com/hiddenkillerspod/Facebook https://www.facebook.com/hiddenkillerspod/Tik-Tok https://www.tiktok.com/@hiddenkillerspodX Twitter https://x.com/TrueCrimePodDisclaimerContent on this site is based on publicly available information and reflects commentary and opinion. All individuals are presumed innocent until proven guilty. Nothing published here constitutes legal, medical, or professional advice.Hashtags#LindsayClancy #DuxburyTragedy #PostpartumPsychosis #TrueCrime #PlymouthCounty #CoraDawsonCallan #InsanityDefense #KevinReddington #TrueCrimeToday #Breaking

Three physicians took the stand today in the murder trial of Lindsay Clancy, the Duxbury, Massachusetts mother accused of strangling her three children — 5-year-old Cora, 3-year-old Dawson, and 7-month-old Callan — with exercise resistance bands inside the family's Summer Street home on January 24, 2023. Clancy faces three counts of murder and three counts of strangulation. She has pleaded not guilty and is mounting an insanity defense, with attorney Kevin Reddington arguing she was in the grip of severe postpartum psychosis and psychiatric overmedication at the time of the killings.Dr. Michael Snyder of Beth Israel Hospital, Dr. Andrew Capraro of the ER at Boston Children's Hospital, and Dr. David Casavant of the ICU at Boston Children's Hospital walked jurors through the children's arrival and treatment — and the brain injuries caused by prolonged oxygen deprivation. The damage was most severe in Callan, the youngest of the three, whose seven-month-old brain had the least capacity to withstand it. These weren't abstract medical terms for the jury. They were a roadmap of exactly what strangulation does to a small child's body, delivered by the people who tried to reverse it and couldn't.Prosecutors are expected to argue Clancy understood the nature of her actions despite the defense's mental-health claims. After the killings, Clancy allegedly attempted to take her own life by jumping from a second-story window, leaving her paralyzed from the waist down. Her husband, Patrick Clancy, was out of the home running errands at the time and has since relocated to Manhattan. The trial, underway in Plymouth Superior Court before Judge William F. Sullivan, is expected to last several weeks.LinksJoin Our SubStack For AD-FREE ADVANCE EPISODES & EXTRAS!: https://hiddenkillers.substack.com/Want to comment and watch this podcast as a video? Check out our YouTube Channel. https://www.youtube.com/channel/UC8-vxmbhTxxG10sO1izODJg?sub_confirmation=1Instagram https://www.instagram.com/hiddenkillerspod/Facebook https://www.facebook.com/hiddenkillerspod/Tik-Tok https://www.tiktok.com/@hiddenkillerspodX Twitter https://x.com/TrueCrimePodDisclaimerContent on this site is based on publicly available information and reflects commentary and opinion. All individuals are presumed innocent until proven guilty. Nothing published here constitutes legal, medical, or professional advice.Hashtags#LindsayClancy #DuxburyTragedy #PostpartumPsychosis #TrueCrime #PlymouthCounty #CoraDawsonCallan #InsanityDefense #KevinReddington #HiddenKillers #Breaking

Officer Richard Lippard of the Duxbury Police Department testified that he spent sixteen hours in a hospital hallway watching Lindsay Clancy lie motionless. She was sedated and unconscious at South Shore Hospital, then MedFlighted to Brigham and Women's in Boston. She never spoke a word during his entire watch. Under cross-examination, Lippard confirmed that a Code Blue was called for her room overnight — meaning she was dead or dying.The testimony came on Day 4 of Clancy's murder trial after the jury walked through the family's former home at 47 Summer Street in Duxbury. Jurors inspected the basement, both floors, and the exterior — including the second-story window and the yard below it. A detective who met Clancy at the hospital described her as sedated and unconscious with deep lacerations across her neck and wrists. Photographs of the injuries and blood in the bedroom were shown to the jury.Two emergency room doctors then testified about treating three-year-old Dawson and eight-month-old Callan. Dawson was worked on for forty minutes before being declared dead. Callan's heart was restarted but he never regained brain function and died at Boston Children's Hospital days later. Clancy was visibly emotional as both doctors described the effort.Every witness Friday was a prosecution witness. And the prosecution's own officer confirmed their defendant was dead or dying the same night they allege she was performing.Join Our SubStack For AD-FREE ADVANCE EPISODES & EXTRAS!: https://hiddenkillers.substack.com/ Want to comment and watch this podcast as a video? Check out our YouTube Channel. https://www.youtube.com/channel/UC8-vxmbhTxxG10sO1izODJg?sub_confirmation=1 Instagram https://www.instagram.com/hiddenkillerspod/ Facebook https://www.facebook.com/hiddenkillerspod/ Tik-Tok https://www.tiktok.com/@hiddenkillerspod X Twitter https://x.com/TrueCrimePodDisclaimer: This publication contains commentary and opinion based on publicly available information. All individuals are presumed innocent until proven guilty in a court of law. Nothing published here should be taken as a statement of fact, health or legal advice.#LindsayClancy #LindsayClancyTrial #HiddenKillers #PlymouthSuperiorCourt #CodeBlue #PostpartumPsychosis #TrueCrime #DuxburyMA #MurderTrial #JuryTrial

New imaging and measurement approaches are revealing previously hidden aspects of microbial life, challenging long-held assumptions and creating opportunities to answer questions that were once out of reach. Marvin Whiteley, Heran Darwin and Jeffrey Moffitt talk about how technological innovation is transforming microbiology. Guests: Heran Darwin, Ph.D. - NYU Grossman School of Medicine Jeffrey Moffitt, Ph.D. - Boston Children's Research This episode of Editors in Conversation is brought to you by mBio® and hosted by mBio Editor in Chief, Marvin Whiteley, Ph.D.  Visit journals.asm.org/journal/mbio to read articles and/or submit a manuscript. Receive up to 50% off fees when you publish in mBio® or any of the ASM journals by becoming an ASM member. Sign up at asm.org/joinasm.

Charles Berde, MD, PhD, is the Sara Page Mayo Chair in Pediatric Pain Medicine and a Professor of Anaesthesia at Harvard Medical School. As a co-founder of the Pain Treatment Center at Boston Children's Hospital, he has spent decades at the forefront of pediatric analgesic pharmacology and the development of novel local anesthetics. His extensive translational research focuses on local anesthetic mechanisms and prolonged-duration formulations, making him a preeminent authority on the physiological impacts and safety profiles of these agents in neonates and children. A recipient of the Myron Yaster Lifetime Achievement Award from the Society for Pediatric Anesthesia, Dr. Berde brings unparalleled expertise to the discussion of managing and preventing local anesthetic systemic toxicity (LAST) within the high-stakes environments of the PICU and pediatric operating rooms.Guest Conflicts of Interest (COI)Algavita Bio: Collaborator/Developer of novel, prolonged-duration local anesthetics.Quiver Bioscience: Unpaid Scientific Advisor and co-PI on an NINDS-HEAL grant focused on rare disease pain treatments.Latigo Biotherapeutics: Scientific Advisor and recipient of past research support for novel analgesics development.Algos: Scientific Advisor for non-opioid analgesics development.Learning Objective: By the end of this podcast, listeners should be able to discuss an evidence-based and expert-guided approach to the management of local anesthetic systemic toxicity (LAST) in children.References:Patient and Doctor Reconcile for Greater GoodBerde CB. Toxicity of local anesthetics in infants and children. J Pediatr. 1993 May;122(5 Pt 2):S14-20. doi: 10.1016/s0022-3476(11)80004-1.McMahon K, Paster J, Baker KA. Local anesthetic systemic toxicity in the pediatric patient. Am J Emerg Med. 2022 Apr;54:325.e3-325.e6. doi: 10.1016/j.ajem.2021.10.021. Epub 2021 Oct 25. Lavonas et al. 2023 American Heart Association Focused Update on the Management of Patients With Cardiac Arrest or Life-Threatening Toxicity Due to Poisoning: An Update to the AHA Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care. Circulation. 2023 Oct 17;148(16):e149-e184. doi: 10.1161/CIR.0000000000001161. Epub 2023 Sep 18. Questions, comments or feedback? Please send us a message at this link (leave email address if you would like us to relpy) Thanks! -Alice & ZacSupport the showHow to support PedsCrit:Please complete our Listener Feedback SurveyPlease rate and review on Spotify and Apple Podcasts!Donations are appreciated @PedsCrit on Venmo , you can also support us by becoming a patron on Patreon. 100% of funds go to supporting the show.Please remember that all content during this episode is intended for educational and entertainment purposes only. It should not be used as medical advice. The views expressed during this episode by hosts and our guests are their own and do not reflect the official position of their institutions. If you have any comments, suggestions, or feedback-you can email us at pedscritpodcast@gmail.com.  You can also check out our website at http://www.pedscrit.com. Thank you for listening to this episode of PedsCrit!

Planet FM-in "Zaman Maşını" verilişində fəlsəfə doktoru, pediatr və dünyanın ən nüfuzlu tibb ocaqlarından olan Boston Children's Hospital-ın (Harvard) elmi işçisi Ülviyyə xanım Aslanova uşaq inkişafı və pediatriya məsələlərini təhlil edir.Autizm spektr pozuntusunun (ASD) artma səbəbləri, ata yaşının autizmə təsiri, Daun sindromu, uşaqlarda erkən inkişaf mərhələləri ("milestones"), peyvəndlər (vaccines) haqqında doğru bilinen yanlışlar və zərərli ekran müddəti (screen time) haqqında ən son elmi faktları bu podcastda dinləyə bilərsiniz.Podcastda cavab tapacağınız kritik suallar:Autizm hallarının dünyada və Azərbaycanda artmasının əsl elmi səbəbləri nələrdir?Ata yaşı və genetik faktorlar autizm riskini necə artırır?Uşaqda "gecikmiş nitq" nə vaxt təhlükə siqnalıdır (red flag)?Peyvəndlər (MMR, Covid və s.) autizmə səbəb olurmu?Körpələrə smartfon verilməsi (screen time) beyin inkişafını necə məhv edir?

What does it take to help children thrive during a hospital stay? In this episode of Inside the Children's Hospital Podcast, Katie Taylor sits down with Alyssa Sachs, CCLS, an inpatient Child Life Specialist at Boston Children's Hospital, to explore how Child Life Specialists help children and families experience joy, connection, and normalcy—even during long and complex hospital stays. Alyssa shares what it's like supporting children on the inpatient neuroscience floor, where patients range from newborns to young adults with epilepsy, neuro-oncology diagnoses, neurosurgical needs, and more. She offers an inside look at the innovative programs that make Boston Children's unique, including gaming and technology specialists, hospital clowns, music therapy, artists-in-residence, facility dogs, and therapeutic events that transform the hospital experience. Throughout the conversation, Alyssa reminds us that it's often the smallest moments, like a surprise snow cone, a movie night on the rooftop, or decorating a hospital room, that leave the biggest impact on children and caregivers alike. Whether you're a parent navigating a hospitalization, a healthcare professional, or simply curious about how Child Life Specialists support patients in pediatric hospitals, this episode is a heartfelt reminder that childhood doesn't have to stop because of illness. In This Episode, We Discuss: What an inpatient Child Life Specialist does Supporting children with neurological and neurosurgical conditions How Child Life Specialists normalize the hospital experience Gaming and technology specialists and therapeutic gaming Hospital clowns, music therapy, artists, and facility dogs Why playrooms matter for patients and siblings Creative ways families can bring "home" into the hospital Supporting caregivers through joyful moments Collaboration between Child Life and the medical team The importance of community partnerships and hospital donors Episode Timestamps 00:00 Meet Alyssa Sachs, CCLS at Boston Children's Hospital 01:04 Why Alyssa became a Child Life Specialist 01:49 Caring for patients on the neuroscience floor 03:55 Programs that make the hospital feel like childhood 07:14 Inside the Gaming & Technology Specialist program 09:33 Bringing the outside world into the hospital 11:21 Why joyful moments matter for caregivers too 12:55 Supporting families through difficult hospital experiences 15:56 Simple ways families can create normalcy in any hospital room 18:51 How Child Life collaborates with nurses and physicians 20:55 Joy carts, lemonade stands, and surprise snow cones 23:08 Why hospital playrooms are so important 25:09 The role of hospital clowns in pediatric care 27:06 Why normalization is essential to healing 27:56 Community partnerships that make it all possible   Resources Mentioned Boston Children's Hospital Child Life Services Hospital Playrooms Gaming & Technology Specialists Music Therapy Artists-in-Residence Hospital Clowns Facility Dog & Paw Prints Programs Connect with Us Instagram: @childlifeoncall + @insidethechildrenshospital Subscribe: Never miss an episode on Apple Podcasts or Spotify. Visit insidethechildrenshospital.com to search stories and episodes easily Leave a Review: It helps other families find us and access our resources  

Erin Lamb has been a speech language pathologist for 26 years. She runs a Baltimore nonprofit with its own school for autistic kids. She has a Ph.D. She still missed her own daughter's autism. Why does autism get missed in girls? Most of the foundational autism research was done on boys. As Erin puts it, everything she knew about autism she learned from boys in the 90s, because that's what the research was done on. That research shaped the training, and the training shaped what people picture when they hear the word autism. Girls who talk early, who mask well, or whose struggles get read as anxiety often reach their teens before anyone says it out loud. This is a Seen and Heard episode, so Erin gets the floor. She walks Rob through what a day actually looks like in a house with a kid in autistic burnout, with a PDA profile and ARFID, where separation anxiety is the most clinically significant thing in the room. She's honest about what it costs her. "People are like, what are you doing this weekend? And my answer is always caregiving. Because I do not know. I cannot plan." Then she tells us what changed. She calls it outsourcing the panic. If the school professional isn't panicking, why is she? She handed the worry to the people whose job it is to worry, and her daughter started coming back to her within weeks. She also gives the best description of an autistic kid this show has had. In the wrong environment it's like parenting all the kids from Willy Wonka at once. In the right one, with the right accommodations and supports, her kid is Charlie. WHAT YOU'LL HEAR Why a speech language pathologist with 26 years of practice missed autism in her own daughter What a day really looks like with a kid in autistic burnout, a PDA profile, and ARFID What outsourcing the panic means, and how she started doing it Who her daughter actually is: the Lorax, Willy Wonka, and Charlie What she wishes the outside world, and the autism community, understood TERMS FROM THIS EPISODE Autism in girls: autism is underdiagnosed in girls largely because the foundational research was conducted on boys, so the diagnostic picture most clinicians trained on describes boys. Girls who mask well or present as anxious are routinely missed. PDA, pathological demand avoidance: a profile in which an autistic person's nervous system treats demands as threats, even small or pleasant ones. Approaches that add pressure usually make it worse. ARFID, avoidant restrictive food intake disorder: more than picky eating. A child avoids whole categories of food by texture, smell, or fear, to the point that nutrition and growth are affected. Autistic burnout: exhaustion and loss of previously held skills following a long stretch of masking, sensory overload, and unmet needs. Recovery takes fewer demands and real rest, not more pushing. Outsourcing the panic: Erin's strategy of handing specific worries to the professionals whose job it is to hold them, instead of carrying every worry herself. ABOUT ERIN LAMB Erin Lamb is the President and CEO of Gateway Maryland, the Baltimore nonprofit formerly known as HASA, which has served Maryland families for nearly 100 years. She's a licensed speech language pathologist, holds a Ph.D. in public policy, and is the mom of two neurodivergent teenage daughters. SPONSOR This episode is sponsored by Mightier, a biofeedback emotional-regulation gaming program for kids, developed and tested at Boston Children's Hospital. Kids wear a heart-rate monitor and play games that get harder when they get dysregulated and easier as they calm down, so they practice regulating themselves in the moment. Read Rob's full review at theautismdad.com/mightier-review and use code theautismdad22 for 10% off. #ad RESOURCES Gateway Maryland: gatewaymaryland.org Rob's full Mightier review: theautismdad.com/mightier-review More Seen and Heard episodes: listen.theautismdad.com Find Rob at theautismdad.com, and on Facebook, Instagram, TikTok, and YouTube at The Autism Dad.

A stranger vanishes into a dead-end Savannah alley, leaving behind a lesson that will last a lifetime. A grieving listener receives possible signs from both her grandmother and beloved dog, while JG recalls the mysterious cab driver who appeared during his family's desperate trip to Boston Children's Hospital—and disappeared before he could be thanked. Also: Ghost the Great Dane and his “trotting farts,” an unexpectedly controversial use for A.1. Sauce, a nature trail shaped like an air freshener, and a listener suggestion involving the horrifying Byford Dolphin decompression accident. Plus, Kat and Jethro prepare for Halloween Quarter and invite the Freak Family to submit their own recorded stories for the annual Halloween special. It's another Inbox of Oddities filled with strange encounters, heartfelt connections, peculiar pets, and the lingering question of whether the signs we ask for may already be all around us. Learn more about your ad choices. Visit megaphone.fm/adchoices

At the International Anesthesia Research Society (IARS) and Society of Critical Care Anesthesiologists (SOCCA) meeting in Montreal, TopMedTalk hosts Mike Grocott and Desiree Chappell speak with Dr Faye Evans, Senior Associate in Perioperative Anesthesia at Boston Children's Hospital and Associate Professor of Anaesthesia at Harvard Medical School and Director of Partnerships on the Board of Directors for the World Federation of Societies of Anaesthesiologists (WFSA). The conversation covers efforts to improve access to safe surgery and anesthesia for children globally. Evans explains the WFSA as a society of over 150 member societies focused on advocacy, safety, quality, publications, short courses (including SAFE), and a fellowship program that has trained over 400 fellows from 62 countries. She highlights growing emphasis on leadership, teaching, and evaluation within fellowships and describes Pediatric Anesthesia Training in Africa (PATA), formed to expand fellowship training, which has developed a shared curriculum and launched four programs with support from ELMA Philanthropies and Smile Train. Evans outlines ways to get involved through teaching, virtual support, and donations via the WFSA website. If you would like to support the WFSA Scholars Program we mention this link in the show: https://wfsahq.org/get-involved/donate/ -- The 2026 International Practicum on Cardiopulmonary Exercise Testing will be held at the Balmer Lawn Hotel in Brockenhurst, UK, from September 16th to 18th this year. It is organised by iPOETTS , the international perioperative testing and training society. Come and join us at this premier educational event designed for clinicians, scientists, and healthcare professionals interested in sport, exercise, and perioperative medicine. This is an International Perioperative Testing and Training Society accredited event so when you attend you can get your iPOETTS accreditation, showing that you are a practitioner who has reached a high, standardized level of competence in performing and interpreting Cardiopulmonary Exercise Testing (CPET) for patients preparing for major surgery. Go now to http://www.ebpom.org

Olympic gold medalist Scott Hamilton joins Sage Steele for one of the most remarkable life stories in sports. Scott opens up about the childhood illness that baffled doctors from Toledo to Boston Children's, being adopted at six weeks old, and the discovery 35 years later that finally explained everything. He shares how getting fired by Ice Capades led him to create Stars on Ice, the disastrous first show that literally caught fire, why he threw his Olympic broadcast binder in the trash, and the moment Kristi Yamaguchi changed the tour forever. Scott also reveals the rule that got him through stage 3 testicular cancer and a brain tumor, the lesson his mother taught him during her own cancer battle, meeting his wife Tracy, adopting two children from Haiti, and the two kinds of criticism every person needs to learn to filter. From living in a friend's basement with a gold medal to selling out Madison Square Garden, this is Scott Hamilton unfiltered on faith, family, failure, and fighting for joy. New episodes of The Sage Steele Show every week. Sponsors: Visit https://GoodRanchers.com and use my code SAGE at checkout to get $50 off anything on their site. Your $17.76 3-week QuickStart is ready for you! Visit https://www.relieffactor.com/ or call 800-4-RELIEF. Provide one life-saving ultrasound for just $28 at https://preborn.com/sage. Use my link to sign up and receive a $100 funding bonus when you create and fund your account: https://www.itrustcapital.com/go/sagesteele BTS on Patreon: http://bit.ly/4nLmOSk The Sage Steele Show is a weekly podcast hosted by former ESPN anchor Sage Steele. Each week, Sage sits down with entertainers, athletes, business people, and politicians to have deep dive personal one on one discussions that enlighten, entertain, and engage. There's a whole big world out there that's not just sports, and Sage wants to talk about all of it. #sagesteelepodcast #sagesteele #podcast Subscribe to the Channel for more Podcasts like this! Listen to the Show on all Podcast Apps "The Sage Steele Show" https://podcasts.apple.com/us/podcast/the-sage-steele-show/id1737682826 Follow Sage: https://www.sagesteele.com https://x.com/sagesteele https://www.instagram.com/sagesteele https://www.tiktok.com/@officialsagesteele https://rumble.com/c/SageSteeleProductions

“Most people don't even tag her with autism, because she's smart, she's so articulate.” Lauren Murray Lauren Murray is a New Jersey mom of two, and her daughters are almost twenty years apart. Her oldest is about to turn 21, a UCF graduate thriving in Florida. Her youngest is four, level two autistic, with sensory processing disorder and a short list of safe foods. She is also, in Lauren's words, doing fantastic. In this Seen and Heard episode, Lauren gives Rob an honest look at a day that starts at six in the morning and does not end until nine at night. Her husband works long days, so most of the week she is her daughter's sole care provider. Lauren is a former teacher who kept a tight schedule at home, and school does it even better, down to the minute, and her daughter loves it. Then there is the part so many parents will feel in their chest. Lauren's daughter is bright and verbal, she speaks better than most of her peers, and that is exactly why people do not believe she is autistic. At the park, one mom packs up her kids and leaves every time she sees them coming, because Lauren's daughter does not understand personal space and just wants to play. In public, a meltdown gets read as a bratty toddler, when the truth is they have done everything from A to Z to get ahead of it. And the win. Flying home from a day trip to visit her oldest in Florida, their flight got canceled. They spent the night in the airport, then got emergency landed at an airport none of them had ever seen. Her four-year-old took the whole thing in stride, iPad, comfort snacks, a blanket Lauren packed just in case, a bench, and a kid who just went with the flow. Lauren also names something a lot of families hit. In New Jersey, the services show up the moment you are diagnosed, but if you do not use them inside six months, they close your file. Not because you will never need help, just because you did not need it that week. What you'll hear: “She took it better than I did.” Lauren Murray This episode is sponsored by Mightier, a biofeedback emotional-regulation gaming program for kids, developed and tested at Boston Children's Hospital. Kids play games that get harder when they get dysregulated and easier as they calm down, so they practice regulating themselves in the moment. Read Rob's full review at theautismdad.com/mightier-review and use code theautismdad22 for 10% off. #ad About Rob: Rob Gorski is the founder of The Autism Dad, a blog and podcast dedicated to supporting parents raising kids on the autism spectrum. As a dad of three autistic sons with over 25 years of experience, Rob brings lived experience, honesty, and heart to every conversation. Rob's book, So Your Child Was Just Diagnosed with Autism, lands December 29, 2026 from Fair Winds Press. Updates and preorder: theautismdad.com/book Where to find Rob: You can find me at theautismdad.com, on Facebook, Instagram, and TikTok at The Autism Dad, and on YouTube at The Autism Dad. New episodes drop every week at listen.theautismdad.com.

Dr. Cohen is a pediatric neurosurgeon with more than four decades of experience treating critically ill children at institutions including Boston Children's Hospital and Johns Hopkins. In his new memoir, Comfort Always: Healing in the Age of Technology he opens up about one of the least discussed realities in medicine: the emotional weight physicians carry when delivering life-and-death diagnoses to children and their families.Through deeply human stories from the operating room, Dr. Cohen explores what it means to guide families through fear, grief, uncertainty, and hope and how compassion and emotional presence often become just as important as medical expertise itself.You can find Dr Cohen here: dralanrcohen.comPlease grab a copy of his book here: https://www.amazon.com/dp/B0G2JVBTJG/ or support your local bookstore!Support me on Patreon! https://www.patreon.com/nikkithedeathdoula⁠Get merch and find any other info you need on the podcast here: www.nikkithedeathdoula.com/podcast

In this episode, Phil DeBruzzi, Principal at Forvis Mazars, and Dr. Ryan Nagy, President and System Chief Operating Officer at Boston Children's Hospital, discuss the forces reshaping pediatric healthcare, from workforce shortages and behavioral health demand to reimbursement pressures and shifting care models.

The Big Unlock · Naomi Fried, PhD, Founder and CEO, PharmStars In this episode, Naomi Fried, PhD, Founder and CEO of PharmStars, shares how stronger collaboration between startups and pharmaceutical companies is accelerating healthcare innovation. Drawing on leadership roles at Biogen, Kaiser Permanente, Boston Children's Hospital, consulting work with large pharma companies, and collaboration across the digital health ecosystem, she explains why the most successful innovations are built around customer needs rather than technology alone. Naomi discusses how PharmStars helps digital health startups, including those developing AI-powered solutions, understand the pharmaceutical industry, refine their value proposition, and build lasting partnerships with global pharma companies. She highlights AI as one of the most exciting areas of innovation, with the potential to improve patient care, support clinicians, and create new opportunities for life sciences organizations. However, Naomi emphasizes that technology alone is never enough. Successful innovators listen more than they pitch, understand customer pain points, and build trusted relationships. Naomi also talks about the importance of clinician workflows, internal champions, and continuous product evolution. Whether leveraging AI, software, or medical devices, her message is clear: lasting innovation comes from solving meaningful problems, adapting to customer needs, and building partnerships that create real-world impact. Take a listen.

This week's Touch Point is an encore. We are replaying TP470, "When AI Becomes the First Stop for Care." It aired in January, the same week OpenAI launched ChatGPT Health. Chris and Reed sat down with Brandon Scott of TenAdams and made a plain argument. For a growing number of patients, the health journey now starts inside an AI chat, before any health system enters the picture. Five months later the premise is no longer up for debate. By OpenAI's count, more than 230 million people ask health questions on ChatGPT every week, and roughly 40 million do it daily. The patient who shows up already holding an AI explanation of their lab results is now routine. What the original episode left open is the reason to replay it. TP470 asked how health systems would respond. The most visible answer so far is that they bought from the same company. OpenAI for Healthcare rolled out inside AdventHealth, Cedars-Sinai, HCA, Boston Children's, Stanford and other systems within a day of the consumer launch. In April, OpenAI put a free tool directly on clinicians' desks. The vendor that became the patient's first stop is now also the clinician's workspace and the enterprise platform. The front door, the exam room and the back office increasingly run through one synthesis layer. In this encore, Chris and Reed cover: Why AI became the first stop for care before most health systems had a strategy for it What ChatGPT Health actually does, and the line between "support" and "diagnosis" that OpenAI keeps drawing Where AI fills the gaps left by short appointments, fragmented records and limited access Why walled garden thinking is out of step with how patients now manage their health What changes when the tool patients trust and the tool clinicians use come from the same vendor If your digital strategy still treats the website as the first interaction, this episode was early to the problem and the problem only got bigger. Mentions from the Show: Original episode: TP470, When AI Becomes the First Stop for Care. https://touchpoint.health/podcast/tp470-when-ai-becomes-the-first-stop-for-care/ OpenAI, Introducing ChatGPT Health (Jan 7, 2026): https://openai.com/index/introducing-chatgpt-health/ OpenAI, Introducing OpenAI for Healthcare (Jan 8, 2026): https://openai.com/index/openai-for-healthcare/ Fierce Healthcare, OpenAI launches ChatGPT for Clinicians (Apr 30, 2026): https://www.fiercehealthcare.com/ai-and-machine-learning/openai-launches-chatgpt-clinicians-free-ai-tool-physicians-nps-and Advisory Board, Ty Aderhold on ChatGPT Health: https://www.advisory.com/daily-briefing/2026/01/12/chatgpt-health-ab-oi-ec TP476, Good Enough for People Is Not Good Enough for Machines: https://touchpoint.health/podcast/tp476-good-enough-for-people-is-not-good-enough-for-machines/ Brandon Scott on LinkedIn: https://www.linkedin.com/in/brandontascott/ TenAdams: http://tenadams.com Reed Smith on LinkedIn: https://www.linkedin.com/in/reedtsmith/ Chris Boyer on LinkedIn: https://www.linkedin.com/in/chrisboyer/ Chris Boyer website: http://www.christopherboyer.com/ Chris Boyer on BlueSky: https://bsky.app/profile/chrisboyer.bsky.social Reed Smith on BlueSky: https://bsky.app/profile/reedsmith.bsky.social Learn more about your ad choices. Visit megaphone.fm/adchoices

In this podcast, recorded at the Top Articles of 2025 Session at PEDICRITICON 2025, Dr. Traci Wolbrink interviews Drs. Ashish Agarwal and Ramesh Kumar Ramachandran about two randomized controlled trials. These studies comparing 0.9% normal saline with Ringer's lactate in diabetic ketoacidosis and the efficacy of high flow nasal cannula versus nasal prong bubble CPAP in bronchiolitis. The conversation reveals challenges in resource-limited settings, emphasizing the importance of protocol adherence, mentorship, and resource management. Valuable insights into fluid management, respiratory support, and research execution are offered for healthcare professionals keen on advancing clinical practice and research knowledge. Learning Objectives - Recognize the limitations of using normal saline in diabetic ketoacidosis - Understand the physiological benefits of balanced fluids like Ringer's Lactate - Identify the logistical challenges in conducting trials in resource-limited settings - Appreciate the role of teamwork and protocol adherence in research success AUTHORS Ashish Agarwal, MD Post Graduate Institute of Medical Education and Research, Chandigarh, Chandigarh, India Ramachandran Rameshkumar, MD, DM, FRCPCH Division of Pediatric Critical Care, Department of Pediatrics, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, India Pediatric Intensive Care Unit, Department of Pediatrics, Mediclinic City Hospital, Mohammed Bin Rashid University of Medicine and Health Sciences, Dubai, United Arab Emirates Traci Wolbrink, MD, MPH‌ Co-Director, OPENPediatrics Senior Associate in Critical Care Medicine Department of Anesthesiology, Critical Care and Pain Medicine Boston Children's Hospital Associate Professor of Anesthesia Harvard Medical School DATE Initial publication date: July 1, 2026. ARTICLES REFERENCED Agarwal A, Jayashree M, Nallasamy K, Dayal D, Attri SV. 0.9% Saline versus Ringer's lactate as initial fluid in children with diabetic ketoacidosis: a double-blind randomized controlled trial. BMJ Open Diabetes Res Care. 2025;13(2):e004623. https://pubmed.ncbi.nlm.nih.gov/40194836/ Maya M, Rameshkumar R, Selvan T, Delhikumar CG. High-Flow Nasal Cannula Versus Nasal Prong Bubble Continuous Positive Airway Pressure in Children With Moderate to Severe Acute Bronchiolitis: A Randomized Controlled Trial. Pediatr Crit Care Med. 2024;25(8):748-757. https://pubmed.ncbi.nlm.nih.gov/38639564/ TRANSCRIPT https://cdn.bfldr.com/D6LGWP8S/as/szcrpthcfg3w4398gkvf9ch/202606_Pedicriticon_Podcast_2025_Transcript Please visit: http://www.openpediatrics.org OPENPediatrics™ is an interactive digital learning platform for healthcare clinicians sponsored by Boston Children's Hospital and in collaboration with the World Federation of Pediatric Intensive and Critical Care Societies. It is designed to promote the exchange of knowledge between healthcare providers around the world caring for critically ill children in all resource settings. The content includes internationally recognized experts teaching the full range of topics on the care of critically ill children. All content is peer-reviewed and open-access thus at no expense to the user. For further information on how to enroll, please email: openpediatrics@childrens.harvard.edu CITATION Agarwal A, Rameshkumar R, Wolbrink TA. PEDICRITICON 2025: Top Articles in PICU Research. 07/2026. OPENPediatrics. Online Podcast. https://soundcloud.com/openpediatrics/pedicriticon-2025-top-articles-in-picu-research.

Ariel Fristoe: Theater as a Civic CommonsWhat happens when theater stops asking audiences simply to watch and starts inviting communities to listen, speak, and act?In this conversation, Bill Cleveland talks with Ariel Fristoe, founder and Artistic Director of Out of Hand Theater in Atlanta, about a lifetime spent reclaiming theater's oldest purpose—not entertainment alone, but civic life. Together they explore how storytelling, conversation, and community partnerships can become practical tools for reducing polarization, strengthening democratic participation, and helping neighbors encounter one another as fellow human beings rather than strangers.From foster parenting to community organizing, from performances in living rooms to citywide dinners on racial equity, Ariel describes a practice built on a deceptively simple recipe: Art to open hearts. Information to open minds. Conversation to inspire action.In this episode:Why theater originally existed as a civic commons—and why Ariel believes it should become one again.The story behind Decatur Dinners, where more than 1,200 strangers gathered in homes across one city for conversations about race.Ariel's vision for a modern “federal theatre project” that would put artists to work helping communities address their most pressing challenges.How community conversations created through theater can strengthen civic participation and democratic life.ART IS CHANGE Episode 184 Notable MentionsPeopleAriel Fristoe — Founder and Artistic Director of Out of Hand Theater, nationally recognized for developing theater-based civic engagement models that combine performance, dialogue, and community action.Bill Cleveland — Host of Art Is Change, artist, researcher, and founder of the Center for the Study of Art & Community.Dr. Martin Luther King Jr. — Civil rights leader whose vision of the “Beloved Community” profoundly influences Ariel's work and the mission of Out of Hand Theater.Bryan Stevenson — Civil rights attorney, founder of the Equal Justice Initiative, and author of Just Mercy. Ariel references his conviction that hope is the enemy of injustice.Malunga Casquelourd — Congolese cultural leader and teaching artist whose work at San Quentin Prison used traditional storytelling, music, and movement to create dialogue across prison factions.Nikki Young — Playwright whose work appears in the Decatur Dinners performance excerpt featured in this episode.Jesenia Ingram — Atlanta actor performing the excerpt from Nikki Young's play during the Decatur Dinners segment.Brian Goldstone — Journalist and anthropologist whose Pulitzer Prize-winning book There Is No Place for Us examines housing insecurity and the working poor in Atlanta.Organizations & InitiativesOut of Hand Theater — Atlanta-based theater company working at the intersection of art, civic engagement, and social justice through performances, community dialogue, and partnerships.Community Impact Lab — Out of Hand Theater's national training initiative helping artists, activists, and community leaders develop arts-based civic engagement projects.“Equitable Dinners” — Out of Hand's signature model combining a short play, shared meal, facilitated dialogue, and concrete civic action.“Shows in Homes” — Long-running initiative bringing professional theater into private homes to spark conversations around difficult community issues.“We Hold These Truths” — Out of Hand Theater's America250 initiative using four original plays and community dinners to encourage conversations across political, racial, and cultural differences.Center for the Study of Art & Community — Producer of Art Is Change.Charles F. Kettering Foundation — Partner through its Democracy and the Arts program.National Endowment for the Arts — Federal arts agency supporting public access to the arts, including Out of Hand's America250 initiative.The King Center — Atlanta institution dedicated to advancing Dr. King's philosophy of nonviolence.The Carter Center — International nonprofit advancing peace, democracy, and public health.National Center for Civil and Human Rights — Atlanta museum and educational center exploring links between the U.S. Civil Rights Movement and global human rights.United Way of Greater Atlanta — Regional nonprofit working to improve education, housing, and economic mobility.Atlanta Regional Commission — Metropolitan planning agency serving the Atlanta region.Mixed Blood Theatre — Minneapolis theater company licensing Out of Hand's community dinner model.RealTime Arts — Pittsburgh arts organization presenting Out of Hand's civic engagement model.Events & ProjectsAmerica250 — National commemoration of the 250th anniversary of the Declaration of Independence, inspiring Out of Hand's “We Hold These Truths” initiative.“Decatur Dinners” — Landmark civic arts initiative in which more than 1,200 participants gathered in homes across Decatur for performances and conversations about racial equity.Publications & ResearchThere Is No Place for Us: Working and Homeless in America — Brian Goldstone's Pulitzer Prize-winning investigation into working homelessness in Atlanta.International Journal of Arts Management — Peer-reviewed journal publishing Ariel Fristoe's research on Out of Hand Theater's community-centered business model.Journal of Arts Management, Law, and Society — Scholarly journal publishing research related to arts management and cultural policy.American Theatre — National publication covering nonprofit theater, including Out of Hand Theater's America250 initiative.“Out of Hand Theater: Monetizing Creativity”— Harvard Business School case study examining Out of Hand Theater's innovative business model.Places & InstitutionsMartin Luther King Jr. National Historical Park — Historic district where Ariel Fristoe lives and works.Hope-Hill Elementary School — Neighborhood school Ariel describes as transforming her understanding of segregation and systemic racism.San Quentin Rehabilitation Center — California correctional institution referenced in Bill Cleveland's story about arts-based conflict resolution.Boston Children's Theatre — Historic theater where

The Endocrine Society recently released a new Clinical Practice Guideline (CPG) on Central Precocious Puberty. Among its many recommendations, the CPG says some subgroups of children with precocious puberty—such as older girls with slowly progressing puberty—may not need the same level of testing or treatment.Central precocious puberty happens when a child's brain activates puberty-related hormones too early—before age 8 years in girls and before age 9 years in boys. This early hormone signaling triggers physical changes such as breast development in girls, testicular enlargement in boys, rapid growth, and, in some cases, early menstruation.Host Aaron Lohr talks with authors of the CPG on Central Precocious Puberty: Ana Latronico, MD, PhD, Professor of Endocrinology and Metabolism at Sao Paolo University and Stephanie Roberts, MD, pediatric endocrinologist and Assistant Professor of Pediatrics at Boston Children's Hospital.

In this World Shared Practice Forum Podcast, first authors Drs. Frances Balamuth and Chanu Rhee describe the objectives and methodology for their study “National Estimates of Pediatric Sepsis in US Hospitals Using Clinical Data” published in the March 2026 edition of JAMA. They discuss the process of modifying the Phoenix Sepsis Criteria to an electronic health record-based Pediatric Sepsis Event (PSE) definition and the methods for validating this definition. The authors share salient findings from their study, noting the limitations, and share their hopes for the future direction of sepsis surveillance research. LEARNING OBJECTIVES - Understand the derivation for the Pediatric Sepsis Event definition for electronic health record-based pediatric sepsis surveillance - Review the validation process for the Pediatric Sepsis Event definition - Compare the Pediatric Sepsis Event definition to the Phoenix Sepsis Criteria - Discuss the results and limitations of the electronic health record-based study design - Express the goals for the future direction of pediatric sepsis surveillance research AUTHORS Frances Balamuth, MD, PhD, MSCE Professor of Pediatrics, Chief of Pediatric Emergency Medicine University of Pennsylvania Perelman School of Medicine Children's Hospital of Philadelphia Chanu Rhee, MD, MPH Associate Professor of Population Medicine Harvard Medical School and Harvard Pilgrim Health Care Institute Traci Wolbrink, MD, MPH‌ Senior Associate in Critical Care Medicine; Department of Anesthesiology, Critical Care and Pain Medicine Boston Children's Hospital Associate Professor of Anesthesia Harvard Medical School DATE Initial publication date: June 23, 2026. ARTICLES REFERENCED Rhee C, Balamuth F, Dysart K, et al. National Estimates of Pediatric Sepsis in US Hospitals Using Clinical Data. JAMA. 2026;335(15):1321-1331. https://pubmed.ncbi.nlm.nih.gov/41865411/ TRANSCRIPT https://cdn.bfldr.com/D6LGWP8S/as/swj4kvkgg686b6p9whmbht/20260622_WSP_Rhee_and_Balamuth_Transcript Please visit: www.openpediatrics.org OPENPediatrics™ is an interactive digital learning platform for healthcare clinicians sponsored by Boston Children's Hospital and in collaboration with the World Federation of Pediatric Intensive and Critical Care Societies. It is designed to promote the exchange of knowledge between healthcare providers around the world caring for critically ill children in all resource settings. The content includes internationally recognized experts teaching the full range of topics on the care of critically ill children. All content is peer-reviewed and open-access, thus at no expense to the user. For further information on how to enroll, please email: openpediatrics@childrens.harvard.edu CITATION Balamuth F, Rhee C, O'Hara JE, Wolbrink TA. National Estimates of Pediatric Sepsis. 06/2026. OPENPediatrics. Online Podcast. https://soundcloud.com/openpediatrics/new-national-estimates-of.

Nick Fletcher discusses all things PAO and hip preservation with Dr. Mike Millis from Boston Children's Hospital. Dr. Millis reflects on the origins of the periacetabular osteotomy, his introduction of this procedure in Boston, defining long term success in hip preservation and the future of the specialty. 

One diagnosis flipped a scientist's entire life upside down, and led her to research that's giving parents real hope.Dr. Theresa Lyons, scientist and autism mom, joins Brigitte Cutshall on Real Things Living to break down what autism actually is — a wide spectrum that can look completely different from one child to the next. She explains why autism is rooted in the nervous system, not "bad behavior," how nutrition and gut health can drive emotional outbursts and hyperactivity, and shares groundbreaking research showing autism isn't always lifelong. This is a conversation full of compassion, science, and hope for parents navigating a new diagnosis.3 Takeaways:(1) Autism is a true spectrum — from nonverbal kids with intense daily-living needs to highly verbal kids whose challenges show up mainly in social communication.(2) Behaviors like anger, hyperactivity, or meltdowns often trace back to the nervous system — infections, nutrition deficiencies, and gut health all play a role.(3) New 2023 research from Boston Children's Hospital found 37% of kids lost their autism diagnosis over time — proof that early, holistic support can change a child's trajectory.If you're a parent navigating an autism diagnosis, visit Dr. Teresa's Navigating AWEtism platform (yes — spelled A-W-E-T-I-S-M) for science-backed support, lab testing, and health coaching. https://awetism.co/work-together

In this Complex Care Journal Club podcast episode, Patricia Basualto discusses a qualitative study of service provider perspectives on access to disability services for children with neurodevelopmental disabilities in British Columbia, Canada. She describes the importance of cross-sectoral collaboration, actionable policy and program recommendations, and next steps from this work.‌ SPEAKER Patricia Basualto, MHP, PhD Candidate Assistant Professor, Physiotherapist Pontificia Universidad Católica de Chile PhD Candidate in Kinesiology (Rehabilitation) University of Calgary HOST Kathleen Huth, MD, MMSc Pediatrician, Complex Care Service, Division of General Pediatrics Boston Children's Hospital Assistant Professor of Pediatrics Harvard Medical School DATE Initial publication date: June 8, 2026. JOURNAL CLUB ARTICLE Basualto P, Senevirathna AM, Seth A, Dimitropoulos G, Zwicker JD. Improving Equitable Access to Disability Services and Support for Children With Neurodevelopmental Disabilities: Service Provider and Decision-Maker Perspectives. Child Care Health Dev. 2026 Jan;52(1):e70213. doi: 10.1111/cch.70213. PMID: 41457809; PMCID: PMC12746062. TRANSCRIPT https://cdn.bfldr.com/D6LGWP8S/as/7wvf65c7rjcxkvvt4vjspx9v/Basualto_Final_Transcript_5-27‌ Clinicians across healthcare professions, advocates, researchers, and patients/families are all encouraged to engage and provide feedback! You can recommend an article for discussion using this form: https://forms.gle/Bdxb86Sw5qq1uFhW6. Please visit: http://www.openpediatrics.org OPENPediatrics™ is an interactive digital learning platform for healthcare clinicians sponsored by Boston Children's Hospital and in collaboration with the World Federation of Pediatric Intensive and Critical Care Societies. It is designed to promote the exchange of knowledge between healthcare providers around the world caring for critically ill children in all resource settings. The content includes internationally recognized experts teaching the full range of topics on the care of critically ill children. All content is peer-reviewed and open-access thus at no expense to the user. For further information on how to enroll, please email: openpediatrics@childrens.harvard.edu CITATION Basualto P, Huth K. Opening a Wider Door: Access to Services for Children with Neurodevelopmental Disabilities‌‌‌. 06/2026. OPENPediatrics. Online Podcast.

In this episode, we explore the staggering $65 billion raise by Anthropic, propelling them beyond OpenAI's valuation and transforming the AI landscape. We also discuss innovative moves by companies like Shift and Asana, tackling community-driven robot training and expanding their tech capabilities amidst an evolving market.Chapters00:00 Introduction00:30 Anthropic's Valuation Surge05:01 Shift's Robot Training Initiative09:28 AI in Healthcare at Boston Children's11:49 Grok's Funding and Independence14:00 Asana Acquires Stack AI Show LinksGet the top 80+ AI Models for $8.99 at AI Box: ⁠⁠https://aibox.aiHow I Grow and Scale My Business with AI: https://www.skool.com/aihustleGet the AI Chat Daily Newsletter: https://www.aichatdaily.com/newsletter

Our guest this week is Hubert Eugene 'Hubie' Jones, of Boston, MA. who has shaped and defined the civic and social landscape of Boston for more than forty-five years. He played a leadership role in the formation, building and rebuilding of at least thirty community organizations within Boston's Black community and across all neighborhoods in the city.Hubie and his wife, Kathy, have been married for 68 years and are the proud parents of eight accomplished and college educated children and grandparents to 10.We learn about a handful of organizations that Hubie helped start, shape or was involved in,  including: 1964 Roxbury Multiservice Center, Massachusetts Advocates for Children, City To City, Boston Children's Choir, City Year, and W.K. Kellogg Foundation Like Warren Buffet is to investments, Hubie is to community service and advocacy.  It's an uplifting story about faith and family as well as advcoacy and service to those marginalized in society, all on this episode of the Special Fathers Network Dad to Dad Podcast.Show Notes -Phone – (617) 332-8183 Email – hjones@cityyear.org Website - https://www.massadvocates.org/Order your copy of the new 21CD book: Dads Raising Chidlren With Special Needs & Disabilities: A Guide For 21st Century Dads on Amazon: https://amzn.to/4tdvjcvJoin 21CD on the SFN U.S. Tour, a 30 day, 50 state, 60+ stop tour taking place from May 21 to June 21, 2026: to strengthen and grow the Special Fathers Network and distribute 2,000 complimentary copies of our new book.  Special Fathers Network –SFN is a dad to dad mentoring program for fathers raising children with special needs. Many of the 800+ SFN Mentor Fathers, who are raising kids with special needs, have said: “I wish there was something like this when we first received our child's diagnosis. I felt so isolated.  There was no one within my family, at work, at church or within my friend group who understood or could relate to what I was going through.”SFN Mentor Fathers share their experiences with younger dads closer to the beginning of their journey raising a child with the same or similar special needs. The SFN Mentor Fathers do NOT offer legal or medical advice, that is what lawyers and doctors do. They simply share their experiences and how they have made the most of challenging situations.Join the SFN U.S. Tour in one of 60+ locations all across the U.S. from May 21st to June 21st.  Go to www.21stCenturyDads.org for additional informaiton. Please conisder hosting, co-hosting or simoly joining the tour near your home.  Check out the 21CD YouTube Channel with dozens of videos on topics relevant to dads raising children with special needs - https://www.youtube.com/channel/UCzDFCvQimWNEb158ll6Q4cA/videosPlease support the SFN. Click here to donate: https://21stcenturydads.org/donate/Special Fathers Network: https://21stcenturydads.org/  

In this episode, we explore the staggering $65 billion raise by Anthropic, propelling them beyond OpenAI's valuation and transforming the AI landscape. We also discuss innovative moves by companies like Shift and Asana, tackling community-driven robot training and expanding their tech capabilities amidst an evolving market.Chapters00:00 Introduction00:30 Anthropic's Valuation Surge05:01 Shift's Robot Training Initiative09:28 AI in Healthcare at Boston Children's11:49 Grok's Funding and Independence14:00 Asana Acquires Stack AI Show LinksGet the top 80+ AI Models for $8.99 at AI Box: ⁠⁠https://aibox.aiHow I Grow and Scale My Business with AI: https://www.skool.com/aihustleGet the AI Chat Daily Newsletter: https://www.aichatdaily.com/newsletter See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In this episode, we explore the staggering $65 billion raise by Anthropic, propelling them beyond OpenAI's valuation and transforming the AI landscape. We also discuss innovative moves by companies like Shift and Asana, tackling community-driven robot training and expanding their tech capabilities amidst an evolving market.Chapters00:00 Introduction00:30 Anthropic's Valuation Surge05:01 Shift's Robot Training Initiative09:28 AI in Healthcare at Boston Children's11:49 Grok's Funding and Independence14:00 Asana Acquires Stack AI Show LinksGet the top 80+ AI Models for $8.99 at AI Box: ⁠⁠https://aibox.aiHow I Grow and Scale My Business with AI: https://www.skool.com/aihustleGet the AI Chat Daily Newsletter: https://www.aichatdaily.com/newsletter See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

It's re-run time, as Lee is off getting ready for the launch of ArtPhilly's What Now: 2026 festival. To that end, we're kicking off summer by chatting about Cape Cod. Sharing his thoughts, feelings, and shark avoidance tips is Joe Fenti, standup comedian and corporate drone/content creator. Follow him on Instagram (@fentifriedchicken) and TikTok. For more on Boston Children's Choir and to register, head to bostonchildrenschorus.org or call 617-245-6036.  Have feedback on this episode or ideas for upcoming topics? DM me on Instagram, email me, or send me a voice memo. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

In this World Shared Practice Forum Podcast, Drs. Mark Peters and Scott Weiss provide their expert insight on the methodology and development of the 2026 International Surviving Sepsis Campaign guidelines. They discuss challenges encountered during the process and review notable changes to these guidelines compared to previous iterations. The authors share the recommendations that will most impact their personal practice for patients with sepsis, and reflect on how we can improve global research infrastructure to address salient knowledge gaps in pediatric critical care. LEARNING OBJECTIVES - Understand the design and methodology for the 2026 Surviving Sepsis Campaign guidelines - Review notable changes in the 2026 sepsis guidelines compared to the 2020 edition - Discuss the implications of the altered recommendations for clinical practice changes - Consider methods to improve global pediatric research infrastructure and data organization AUTHORS Mark Peters, MBChB, PhD, MRCP, FFICM, FRCPCH Professor of Paediatric Intensive Care NIHR Senior Investigator UCL Great Ormond St Institute of Child Health Hon. Consultant Paediatric Intensivist Paediatric Intensive Care Unit and Children's Acute Transport Service Great Ormond St Hospital Scott Weiss, MD, MSCE Professor of Pediatrics and Pathology & Genomic Medicine, Division Chief of Critical Care, Vice-Chair of Research for the Department of Pediatrics, Nemours Children's Hospital, Sidney Kimmel Medical College at Thomas Jefferson University Jeffrey Burns, MD, MPH Emeritus Chief Division of Critical Care Medicine Department of Anesthesiology, Critical Care and Pain Medicine Boston Children's Hospital Professor of Anesthesia Harvard Medical School DATE Initial publication date: May 26, 2026. ARTICLES REFERENCED & ADDITIONAL REFERENCES - Weiss SL, Peters MJ, Oczkowski SJW, et al. Surviving Sepsis Campaign International Guidelines for the Management of Sepsis and Septic Shock in Children 2026. Pediatr Crit Care Med. 2026;27(4):379-434. https://pubmed.ncbi.nlm.nih.gov/41869844/ - Balamuth F, Weiss SL, Long E, et al. Balanced Fluid or 0.9% Saline in Children Treated for Septic Shock. N Engl J Med. Published online April 24, 2026. https://pubmed.ncbi.nlm.nih.gov/42028918/ - Weiss SL, Balamuth F, Long E, et al. PRagMatic Pediatric Trial of Balanced vs nOrmaL Saline FlUid in Sepsis: study protocol for the PRoMPT BOLUS randomized interventional trial. Trials. 2021;22(1):776. Published 2021 Nov 6. https://pubmed.ncbi.nlm.nih.gov/34742327/ - Steven Pinker "Enlightenment Now” - https://stevenpinker.com/publications/enlightenment-now-case-reason-science-humanism-and-progress - Blood Poison: The Untold Story of Sepsis - https://amplifypublishinggroup.com/product/nonfiction/health-medicine-and-wellness/general-health-medicine-and-wellness/blood-poison/ TRANSCRIPT https://cdn.bfldr.com/D6LGWP8S/at/r9q8w9vhsbpg7wwzn35kbmz/202605_WSP_Peters_and_Weiss_Transcript.pdf Please visit: http://www.openpediatrics.org OPENPediatrics™ is an interactive digital learning platform for healthcare clinicians sponsored by Boston Children's Hospital and in collaboration with the World Federation of Pediatric Intensive and Critical Care Societies. It is designed to promote the exchange of knowledge among healthcare providers worldwide who care for critically ill children across all resource settings. The content includes internationally recognized experts teaching the full range of topics on the care of critically ill children. All content is peer-reviewed and open-access, thus at no expense to the user. For further information on how to enroll, please email: openpediatrics@childrens.harvard.edu CITATION Peters MJ, Weiss SL, O'Hara J, Burns JP. Pediatric Surviving Sepsis: Insights From the Leadership. 05/2026. OPENPediatrics. Online Podcast. https://soundcloud.com/openpediatrics/pediatric-surviving-sepsis-insights-from-the-leadership-by-m-peters-s-weiss-openpediatrics.

In this episode of Beyond the Torch, hosts Todd Herzog and Leslie Nease welcome the legendary Survivor: Panama player Terry Dietz, catching up with him from his current perch in the Bahamas. They open with a touching fan message from Brandon Jesse about how Survivor built community in his life, then dive into Terry's journey — from watching Tom Westman win and deciding to audition, to his memorable run against a tribe of D1 athletes, and the infamous one-inch, one-second mistake that cost him the immunity challenge (and the million dollars) against Aras. The conversation shifts to Terry's Second Chances season, where he was pulled from the game mid-episode when his son Danny was rushed to Boston Children's Hospital with a dangerously failing heart — an ejection fraction of just 8 — requiring open-heart surgery and ultimately a heart transplant on 9/11, 2016, after nearly 90 days in the hospital. Terry updates us on Danny today: now engaged, thriving in San Jose, and the true "second chance" of Terry's life. The episode also covers the current Survivor 50 season (heaping praise on Rick Devens and discussing Oscar's big gameplay mistake), a lively debate about whether Terry would ever play again, the news that Todd has been invited to the live finale in LA, Leslie sharing that her husband just had successful prostate cancer surgery, and warm reflections on the unique brotherhood that Survivor creates among players and fans alike.Special thanks to the best Whiskey on the Planet Watertown Whiskey! Check them out on instagram: https://www.instagram.com/watertownwhiskey/?hl=en Tell them Fairplay sent you! Please Drink Responsibly https://watertownwhiskey.com/Our new Website is live! Check it out at: www.realityaftershow.comJoin our Patreon at RealityPatron.comIf you would like a cameo from Jonny Fairplay order one now! cameo.com/jonnyfairplayCheck us out on Tiktok @fairplaytokBecome a supporter of this podcast: https://www.spreaker.com/podcast/reality-after-show--5448874/support.

In this special Complex Care Journal Club podcast episode, co-hosts Drs. Emily Goodwin, Kristie Malik, and Kathleen Huth interview presenters of posters and oral abstracts relevant to the care of children with medical complexity at the Pediatric Academic Societies (PAS) 2026 annual meeting, as well as at a pre-PAS event focused on home- and community-based care and training in complex care. Speakers describe their key findings, messages for care teams including patients and families, and opportunities to translate their findings into practice.‌ SPEAKERS Flor Arellano, MPH Clinical Research Coordinator, University of California, Los Angeles Jennifer Arnold, MD, MSc Medical Director, Skeletal Health, Boston Children's Hospital Ryan Brewster, MD Neonatal- Perinatal Medicine Fellow, Stanford University School of Medicine Meg Comeau, MHA Senior Project Director, Center for Innovation in Social Work & Health, Boston University School of Social Work John Greenwood, PT Executive Director for Physical Therapy, Occupational Therapy and Rehabilitation Services, Boston Children's Hospital Elaine Lin, MD Complex Care Pediatrician, Boston Children's Hospital Michelle Macy, MD, MS Professor of Pediatrics, Northwestern University Feinberg School of Medicine Scientific Director, Community, Population Health, and Outcomes, Research and Evaluation Center, Ann & Robert H. Lurie Children's Hospital of Chicago Ashley Nmoh, BA Medical Student, Duke University School of Medicine Jennifer Peralta, MD, MSHPN Assistant Clinical Professor, University of California, Los Angeles Nora Renthal, MD, PhD Assistant Professor of Pediatric Endocrinology, Boston Children's Hospital Erin Ward, MEd Patient Engagement Consultant, Complex Care Service, Boston Children's Hospital HOSTS Emily J. Goodwin, MD Clinical Associate Professor of Pediatrics, University of Missouri Kansas City School of Medicine Pediatrician, General Academic Pediatrics Beacon Program, Children's Mercy Kansas City Kristina Malik, MD Assistant Professor of Pediatrics, University of Colorado School of Medicine Medical Director, KidStreet Pediatrician, Special Care Clinic, Children's Hospital Colorado Kathleen Huth, MD, MMSc Pediatrician, Complex Care Service, Division of General Pediatrics, Boston Children's Hospital Assistant Professor of Pediatrics, Harvard Medical School DATE Initial publication date: May 11, 2026. ARTICLES REFERENCED - Brewster RC, Kats DJ, Elborki M, Chilukuri N, Ray M, Shaar N, Hron J, Khan A. Clinical Outcomes of Postedited Artificial Intelligence Translation for Discharge Instructions. Hosp Pediatr. 2026 Apr 10:e2025008986. doi: 10.1542/hpeds.2025-008986. Epub ahead of print. PMID: 41956490. - FamilyCIRCLE. University of Wisconsin–Madison, Department of Pediatrics. Accessed May 4, 2026. https://familycircle.pediatrics.wisc.edu/ - Pediatric Academic Societies. Online program guide. Accessed May 4, 2026. https://2026.pas-meeting.org/ - Pediatric Academic Societies. Who we are. Accessed May 4, 2026. https://www.pas-meeting.org/about/ - Pediatric Academic Societies. Academic Pediatric Association (APA) awards. Accessed May 4, 2026. https://www.pas-meeting.org/2026-awards-apa/‌ TRANSCRIPT https://cdn.bfldr.com/D6LGWP8S/as/k7qqm93qqpqgb5k3jw4f3w2t/PAS_2026_conference_transcript_5-8-26‌ Clinicians across healthcare professions, advocates, researchers, and patients/families are all encouraged to engage and provide feedback! You can recommend an article for discussion using this form: https://forms.gle/Bdxb86Sw5qq1uFhW6. CITATION Goodwin EJ, Malik K, Arellano F, Arnold J, Brewster R, Comeau M, Greenwood J, Lin E, Macy M, Nmoh A, Peralta J, Renthal N, Ward E, Huth K. Practice-Changing Research in Complex Care at the Pediatric Academic Societies 2026 Annual Meeting. 05/2026. OPENPediatrics. Online Podcast. https://soundcloud.com/openpediatrics/practice-changing-research-in-complex-care-pediatric-academic-societies-2026.

This episode of the World PICU Awareness Week 2026 podcast series explores the realities of working in pediatric intensive care across the Middle East, with a focus on the wellbeing of healthcare professionals. Through expert insights and real-life experiences, the discussion highlights the emotional impact of high-intensity PICU environments – moving beyond burnout to address deeper challenges such as moral distress and moral injury. Practical strategies are shared, from simple daily practices that strengthen team connection to structured organizational initiatives that support resilience and retention. The episode also examines the role of leadership in fostering psychologically safe environments, as well as the influence of culture, family dynamics, and faith in shaping care across the region. HOST Raghad Al Abdwani Head of Division of Pediatric Critical Care Sultan Qaboos. University Hospital, University Medical City, Muscat, Oman GUEST Marianne Majdalani Head of Division of Pediatric Critical Care American University of Beirut Medical Center Ashley Cowan Clinical Nurse Facilitator Sidra Hospital Caroline McIntire Manager of Child Life Services Sidra Medicine DATE Initial publication date: May 8, 2026 TRANSCRIPTS English - https://cdn.bfldr.com/D6LGWP8S/as/qjxhnqx8jt9zvn848svp2955/Middle_East_26_transcript Spanish - https://cdn.bfldr.com/D6LGWP8S/as/qjxhnqx8jt9zvn848svp2955/Middle_East_26_transcript?position=7 French - https://cdn.bfldr.com/D6LGWP8S/as/qjxhnqx8jt9zvn848svp2955/Middle_East_26_transcript?position=3 Portuguese - https://cdn.bfldr.com/D6LGWP8S/as/qjxhnqx8jt9zvn848svp2955/Middle_East_26_transcript?position=6 Italian - https://cdn.bfldr.com/D6LGWP8S/as/qjxhnqx8jt9zvn848svp2955/Middle_East_26_transcript?position=5 German - https://cdn.bfldr.com/D6LGWP8S/as/qjxhnqx8jt9zvn848svp2955/Middle_East_26_transcript?position=4 Arabic - https://cdn.bfldr.com/D6LGWP8S/as/qjxhnqx8jt9zvn848svp2955/Middle_East_26_transcript?position=2 Please visit: www.openpediatrics.org OPENPediatrics™ is an interactive digital learning platform for healthcare clinicians sponsored by Boston Children's Hospital and in collaboration with the World Federation of Pediatric Intensive and Critical Care Societies. It is designed to promote the exchange of knowledge between healthcare providers around the world caring for critically ill children in all resource settings. The content includes internationally recognized experts teaching the full range of topics on the care of critically ill children. All content is peer-reviewed and open-access, thus at no expense to the user. For further information on how to enroll, please email: openpediatrics@childrens.harvard.edu Please note: OPENPediatrics does not support or control any related videos in the sidebar; these are placed by YouTube. We apologize for any inconvenience this may cause.

In this North America episode of the World PICU Awareness Week 2026 podcast, leading experts explore how leadership directly influences caregiver wellbeing and burnout in pediatric intensive care. Through practical examples and evidence-based insights, the discussion highlights the importance of listening to teams, addressing system-level challenges, and fostering a culture where wellbeing is embedded into everyday practice. From leadership behaviors to institutional support, this episode emphasizes a clear message: sustainable PICU care starts with how we lead. HOST Leah Harris Professor and Chair, Department of Pediatrics Dell Medical School at the University of Texas at Austin - Dell Children's Hospital GUEST Asha N Shenoi Professor, Associate Dean University of Kentucky Will Border Chief Physician Wellness Officer, Director of Noninvasive Cardiac Imaging Children's Healthcare of Atlanta and Emory University School of Medicine Wendy Quiroz Nasser Pediatric Nurse Practitioner Baylor College of Medicine (BCM) | Texas Children's Hospital DATE Initial publication date: May 7, 2026 TRANSCRIPTS English - https://cdn.bfldr.com/D6LGWP8S/as/jcbg3x5x35f4sb3wct2kx89w/North_America_26_transcript Spanish - https://cdn.bfldr.com/D6LGWP8S/as/jcbg3x5x35f4sb3wct2kx89w/North_America_26_transcript?position=7 French - https://cdn.bfldr.com/D6LGWP8S/as/jcbg3x5x35f4sb3wct2kx89w/North_America_26_transcript?position=3 Portuguese - https://cdn.bfldr.com/D6LGWP8S/as/jcbg3x5x35f4sb3wct2kx89w/North_America_26_transcript?position=6 Italian - https://cdn.bfldr.com/D6LGWP8S/as/jcbg3x5x35f4sb3wct2kx89w/North_America_26_transcript?position=5 German - https://cdn.bfldr.com/D6LGWP8S/as/jcbg3x5x35f4sb3wct2kx89w/North_America_26_transcript?position=4 Arabic - https://cdn.bfldr.com/D6LGWP8S/as/jcbg3x5x35f4sb3wct2kx89w/North_America_26_transcript?position=2 Please visit: www.openpediatrics.org OPENPediatrics™ is an interactive digital learning platform for healthcare clinicians sponsored by Boston Children's Hospital and in collaboration with the World Federation of Pediatric Intensive and Critical Care Societies. It is designed to promote the exchange of knowledge between healthcare providers around the world caring for critically ill children in all resource settings. The content includes internationally recognized experts teaching the full range of topics on the care of critically ill children. All content is peer-reviewed and open-access, thus at no expense to the user. For further information on how to enroll, please email: openpediatrics@childrens.harvard.edu Please note: OPENPediatrics does not support or control any related videos in the sidebar; these are placed by YouTube. We apologize for any inconvenience this may cause.

This podcast reviews cyanotic congenital heart disease in newborns, including truncus arteriosus, transposition of the great arteries, tricuspid atresia, tetralogy of Fallot, and total anomalous pulmonary venous return. It summarizes their key pathophysiology, presentation, imaging findings, and initial management leading to neonatal cyanosis. LEARNING OBJECTIVES • Explain the pathophysiology for each of the diseases • Recognize the physical exam findings for these heart defects • Identify the different diseases based on imaging • Formulate an initial treatment plan AUTHORS Julia Pian, MD, MBA Pediatric Hospitalist Boston Medical Center Jaclyn McKinstry, MD Pediatric Critical Care Fellow Boston Children's Hospital DATE Initial publication date: May 5, 2026. Please visit: http://www.openpediatrics.org OPENPediatrics™ is an interactive digital learning platform for healthcare clinicians sponsored by Boston Children's Hospital and in collaboration with the World Federation of Pediatric Intensive and Critical Care Societies. It is designed to promote the exchange of knowledge between healthcare providers around the world caring for critically ill children in all resource settings. The content includes internationally recognized experts teaching the full range of topics on the care of critically ill children. All content is peer-reviewed and open-access thus at no expense to the user. For further information on how to enroll, please email: openpediatrics@childrens.harvard.edu CITATION Pian J, McKinstry J, Fantasia K, Marques B, Wills K, Wolbrink TA. Congenital Heart Disease. 05/2026. Online Podcast. OPENPediatrics. https://soundcloud.com/openpediatrics/congenital-heart-disease-by-j-pian-j-mckinstry-for-openpediatrics.

In this episode of the World PICU Awareness Week 2026 podcast series, we explore caregiver wellbeing through the perspective of PICU teams across Africa. Moderated by Dr. Charlyne Kilba, this discussion brings together multidisciplinary voices from across the continent, highlighting both the shared challenges and the strength of teams working in resource-limited, high-demand environments. The conversation provides an honest reflection on the realities of pediatric critical care in Africa – including staff shortages, high patient volumes, ethical dilemmas, and limited access to essential resources – and how these factors impact the wellbeing of healthcare professionals. At the same time, the episode showcases powerful and practical approaches to support caregivers, including team-based support systems, debriefing practices, spirituality, and community-driven initiatives. A strong emphasis is placed on resilience – not only at the individual level, but as a collective and system-supported effort. HOST Marie-Charlyne Kilba Paediatric Intensivist, Head of Department Child Health, Greater Accra Regional Hospital, Ghana GUEST Ireen Primrose Machira Nursing Officer PICU in the Mercy James Centre, Malawi Rohini Kalagouda Patil Lead Paediatric Intesivist Nairobi Hospital, Kenya Susan Zakariah Paediatric emergency and critical care specialist, Head of the PICU Korle Bu Teaching Hospital, Ghana Brenda Morrow Physiotherapist University of Cape Town, South Africa DATE Initial publication date: May 6, 2026 TRANSCRIPTS English - https://cdn.bfldr.com/D6LGWP8S/as/4rpjqpv6nxzcxf7w78z9h4z/Africa_26_transcript Spanish - https://cdn.bfldr.com/D6LGWP8S/as/4rpjqpv6nxzcxf7w78z9h4z/Africa_26_transcript?position=6 French - https://cdn.bfldr.com/D6LGWP8S/as/4rpjqpv6nxzcxf7w78z9h4z/Africa_26_transcript?position=7 Portuguese - https://cdn.bfldr.com/D6LGWP8S/as/4rpjqpv6nxzcxf7w78z9h4z/Africa_26_transcript?position=5 Italian - https://cdn.bfldr.com/D6LGWP8S/as/4rpjqpv6nxzcxf7w78z9h4z/Africa_26_transcript?position=4 German - https://cdn.bfldr.com/D6LGWP8S/as/4rpjqpv6nxzcxf7w78z9h4z/Africa_26_transcript?position=3 Arabic - https://cdn.bfldr.com/D6LGWP8S/as/4rpjqpv6nxzcxf7w78z9h4z/Africa_26_transcript?position=2 Please visit: www.openpediatrics.org OPENPediatrics™ is an interactive digital learning platform for healthcare clinicians sponsored by Boston Children's Hospital and in collaboration with the World Federation of Pediatric Intensive and Critical Care Societies. It is designed to promote the exchange of knowledge between healthcare providers around the world caring for critically ill children in all resource settings. The content includes internationally recognized experts teaching the full range of topics on the care of critically ill children. All content is peer-reviewed and open-access, thus at no expense to the user. For further information on how to enroll, please email: openpediatrics@childrens.harvard.edu Please note: OPENPediatrics does not support or control any related videos in the sidebar; these are placed by YouTube. We apologize for any inconvenience this may cause.

In this episode of the World PICU Awareness Week 2026 podcast series, we explore caregiver wellbeing through the lens of Latin America – a region characterized by resilience, diversity, and a strong commitment to delivering high-quality care in often resource-constrained environments. Moderated by Dr. Lorena Acevedo, this conversation brings together multidisciplinary perspectives from across the region, including physicians, nursing, and allied health professionals. The discussion highlights innovative and structured approaches to caregiver support, such as the CRECEP model, which integrates “caring for the caregiver” as a core pillar of care. It also explores how institutional programs, peer support, education, and simulation contribute to building safer and more supportive environments for healthcare professionals. HOST Lorena Acevedo Pediatric Intensivist Fundación CardioInfantil GUEST Teresa Stegman CICU Nurse Practitioner CHOP Luis Moya Pediatric Intensivist Hospital San Juan de Dios Daniel Sandoval Respiratory Therapist Fundación valle del Lili DATE Initial publication date: May 5, 2026 TRANSCRIPTS English - https://cdn.bfldr.com/D6LGWP8S/as/vz6... Spanish - https://cdn.bfldr.com/D6LGWP8S/as/vz6... French - https://cdn.bfldr.com/D6LGWP8S/as/vz6... Portuguese - https://cdn.bfldr.com/D6LGWP8S/as/vz6... Italian - https://cdn.bfldr.com/D6LGWP8S/as/vz6... German - https://cdn.bfldr.com/D6LGWP8S/as/vz6... Arabic - https://cdn.bfldr.com/D6LGWP8S/as/vz6... Please visit: www.openpediatrics.org OPENPediatrics™ is an interactive digital learning platform for healthcare clinicians sponsored by Boston Children's Hospital and in collaboration with the World Federation of Pediatric Intensive and Critical Care Societies. It is designed to promote the exchange of knowledge between healthcare providers around the world caring for critically ill children in all resource settings. The content includes internationally recognized experts teaching the full range of topics on the care of critically ill children. All content is peer-reviewed and open-access, thus at no expense to the user. For further information on how to enroll, please email: openpediatrics@childrens.harvard.edu Please note: OPENPediatrics does not support or control any related videos in the sidebar; these are placed by YouTube. We apologize for any inconvenience this may cause.

In this episode of the World PICU Awareness Week 2026 podcast series, we explore caregiver wellbeing through a Nordic perspective, with contributions from clinicians and researchers across Europe. Moderated by Prof. Janet Mattsson, this discussion brings together experienced PICU professionals from Sweden and Denmark to reflect on how wellbeing is supported in daily clinical practice. The conversation highlights the importance of structured approaches – from team check-ins and mentorship to ethical discussions and simulation-based learning – while also acknowledging the real challenges of implementing these practices in busy, high-demand PICU environments. HOST Janet Mattsonn Professor of Critical Care nursing Linnaeus University GUEST Johanne Meijers IC nurse Karolinska Universitetssjukhuset Solna Rikke Louise Stenkjaer Researcher Copenhagen University Hospital DATE Initial publication date: May 4, 2026 TRANSCRIPTS English - https://cdn.bfldr.com/D6LGWP8S/as/pbp7m6rprj24tc8b4hnthjcp/Europe_26_transcript Spanish - https://cdn.bfldr.com/D6LGWP8S/as/pbp7m6rprj24tc8b4hnthjcp/Europe_26_transcript?position=6 French - https://cdn.bfldr.com/D6LGWP8S/as/pbp7m6rprj24tc8b4hnthjcp/Europe_26_transcript?position=3 Portuguese - https://cdn.bfldr.com/D6LGWP8S/as/pbp7m6rprj24tc8b4hnthjcp/Europe_26_transcript?position=7 Italian - https://cdn.bfldr.com/D6LGWP8S/as/pbp7m6rprj24tc8b4hnthjcp/Europe_26_transcript?position=5 German - https://cdn.bfldr.com/D6LGWP8S/as/pbp7m6rprj24tc8b4hnthjcp/Europe_26_transcript?position=4 Arabic - https://cdn.bfldr.com/D6LGWP8S/as/pbp7m6rprj24tc8b4hnthjcp/Europe_26_transcript?position=2 Please visit: www.openpediatrics.org OPENPediatrics™ is an interactive digital learning platform for healthcare clinicians sponsored by Boston Children's Hospital and in collaboration with the World Federation of Pediatric Intensive and Critical Care Societies. It is designed to promote the exchange of knowledge between healthcare providers around the world caring for critically ill children in all resource settings. The content includes internationally recognized experts teaching the full range of topics on the care of critically ill children. All content is peer-reviewed and open-access, thus at no expense to the user. For further information on how to enroll, please email: openpediatrics@childrens.harvard.edu Please note: OPENPediatrics does not support or control any related videos in the sidebar; these are placed by YouTube. We apologize for any inconvenience this may cause.

366: Stop Writing for Your Organization. Write for Your Donor. (Tom Ahern)Episode SummaryMost nonprofit communications are, in Tom Ahern's blunt assessment, built to fail. Not because the work isn't worthy, but because organizations keep writing about themselves when they should be writing for the donor. In episode #366, Patton sits down with Tom Ahern, founder of Ahern Communications, Inc. and one of the most influential voices in fundraising copywriting, to unpack why so many appeals, newsletters, and annual reports fall flat. Drawing on decades of commercial copywriting experience before he “wandered into” the nonprofit sector, Tom walks listeners through the three questions every case for support must answer (Why us? Why now? Why you, the donor?) and explains why urgency without desperation, emotion over information, and a relentless focus on the reader are the difference between a gift and a pass. He shares a remarkable story of a Boys & Girls Club that owned a million-dollar crisis and came back stronger, makes the case that donors are already 99% of the way there, and offers a clear-eyed take on what AI can and cannot do for fundraising writers. Listeners will leave with a practical framework they can apply to their next appeal this week, a sharper understanding of donor psychology, and permission to stop trying to inform their way to a gift.About TomTom Ahern is the founder of Ahern Communications, Inc. and one of the leading voices in donor communications and fundraising copywriting. His clients have ranged from Save the Children US and Catholic Relief Services to the Animal Rescue League of Boston, Boston Children's Hospital, the Anchorage Museum, and universities including Princeton, Carleton, and the University of Saskatchewan. He came to the nonprofit sector after fifteen years as a commercial copywriter, led, as he puts it, by an angel: his wife Simone, a longtime development professional and consultant. Since then he has coached fundraisers on best practices in appeals, newsletters, and cases for support, led communications audits (he prefers to call them “autopsies”), and trained nonprofit teams on four continents. Tom is the author of eight how-to books on donor communications, each rated 4.5 stars or higher on Amazon, and a sought-after faculty member for masterclasses and webinars. These days he volunteers most of his coaching hours for small and mid-sized charities, and still keeps Jerry Weissman's book on his desk, the spine sun-bleached from daily use.ResourcesConnect with Tom on LinkedInLearn more at Ahern CommunicationsTom's case-for-support framework: Why us? Why now? Why you, the donor?Book recommendation: Presenting to Win: The Art of Telling Your Story by Jerry WeissmanTom's books on donor communications, including Keep Your Donors (co-authored with Simone Joyaux), available on AmazonFollow Your Path to Nonprofit Leadership, and please leave a review!Learn more about the leadership resources at Armstrong McGuire: ArmstrongMcGuire.com

A chance phone call between Amy Davis and a friend who was taking her daughter to get checked for allergies, led Amy to take her then 2 year and 10 month old daughter Phoebe to see her Pediatrician, where shortly thereafter she was diagnosed with Acute Lymphoblastic Leukemia in June of 2010. Phoebe was in Boston Children's Hospital for 8 weeks and completed her treatment as an outpatient for the next 26 months, until she was 5 years old. From that time on Phoebe has been cancer free with no long term side effects, and is feeling great as an 18 year old. It is always nice to talk about successful Pediatric Cancer journey's on this podcast. 

Send us Fan MailDr. Ofer Levy, director of the Precision Vaccines Program at Boston Children's Hospital and member of the FDA's Vaccines and Related Biologic Products Advisory Committee, makes the case that vaccines must be tailored to the immune system of the person receiving them — and that immune system changes dramatically from the moment of birth through old age. He explains why preterm infants, who represent 11% of births worldwide, carry an increased risk of infection-related hospitalization all the way through age 18, and why almost no investment has been made in understanding how to optimally immunize them. He also discusses the FDA Modernization Act 2.0, which is shifting vaccine development away from animal models toward human in vitro modeling and systems biology, and reflects on what precision vaccinology could mean for rebuilding public trust in a deeply polarized conversation — not by dismissing concerns, but by taking vaccine safety science more seriously than ever before.Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below.Enjoy!

Send us Fan MailDr. Sharon Levy, director of the Division of Addiction Medicine at Boston Children's Hospital, joins Daphna for a wide-ranging conversation on adolescent substance use. She shares data showing a sudden spike in nicotine exposure among teens in treatment for substance use disorders — likely driven by larger vape devices and cooling agents that eliminate the burn sensation — and introduces one of the most novel concepts in addiction medicine: a vaccine that would create antibodies against fentanyl, blocking its effect at the meningeal level before it reaches the brain. She also presents findings on why current surveillance questions fail to capture how teens actually talk about drug use, and why kids who need treatment most are paradoxically the ones most likely to answer screening questions honestly.Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below.Enjoy!

Explore evidence-based clinical signs, diagnostic accuracy, and practical assessment strategies to optimize care with an in-depth look at the latest information on pediatric concussion. JAMA Review author Sonal N. Shah, MD, MPH, of Boston Children's Hospital, discusses this and more with JAMA Associate Editor David Simel, MD, MHS. Related Content: Does This Child Have a Concussion? Even Mild Concussions Tied to Worse Cognition Later in Life Vestibular/Ocular Motor Screening (VOMS) in Suspected Concussion Balance and Gait Assessment Including Modified BESS Cervical Spine Examination in Suspected Concussion